BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000009482 (supercontig:LSalAtl2s:LSalAtl2s611:16796:20138:-1 gene:EMLSAG00000009482 transcript:EMLSAT00000009482 description:"maker-LSalAtl2s611-augustus-gene-0.6")

HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0
Identity = 308/706 (43.63%), Postives = 442/706 (62.61%), Query Frame = 0

Query:   62 CLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENS--FSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITGPSISRD--ETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGD----------------GNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            C+S  CIT A ++ +NMD   DPC DF++F+CG FI  T+IP +++  + F+ +S+ + A+ R +LE      +   F+ AK +Y  CM+++++E LG +P+K +L  LGGWP +   SW      + W+ +  ++   G     ++   VA D KNSS+R++ LDQP   + REYLIKGF D DVQ YY FM+  A   G  E +   ++K+ L  E++LAN S PRE RR+ TKLYN   + ++  L      W+D+IN+I+T   I  +  E IIV  P Y+++ + +I +T+ RV ANYL WRVV    ++LN+ A+ + L+++K LTG   +TPRW+ C +      T+        G+MY  ++F  E++     ++  +R  F  IL  IDWMD KT+  A++K + I ++I YP E+LD +K++ LY  LQ+G  H + N LN+T++  ++    LRE V++ DW+  G  A+VNAFY+P +N I FPAGILQG FF    P Y+N+GAIG VIGHEITHGFDD+GRQFD +                GNL DWW   TK+Q+++K KCII+QYG Y   ++++ LNG+ TQGENIADNGG+KEAY  Y  W  D  + E  LPGL +S KQLFW+S   VWCAK+R +ALK ++ TG HSP+ FR+ GP SN  EFA+DF C  G+ MNP K+C VW
Sbjct:   97 CMSKGCITTASEILRNMDESVDPCEDFYRFSCGGFIDKTIIPDDRTRMSSFSVLSDELLAQVRYLLESESLANEPRPFRMAKDVYNACMNKEQIEVLGQDPIKNILDRLGGWPVIIGDSWNNGGKPYVWYKQVYMLRRIGYSVDYLVDFSVAIDLKNSSRRILDLDQPRFVLDREYLIKGFNDEDVQAYYEFMMDVARFFGANENRAAKDMKEVLELEMKLANFSLPRENRRNATKLYNPMTIKDLTKLDPF-TPWLDYINNILTKEIIQVNDKEVIIVNVPSYIKNFSLLINNTSDRVKANYLLWRVVSASIKYLNDDAKKISLQFSKKLTGKTEETPRWRTCVDGAKRSLTN------AVGAMYIRKYFKEESRKSACEMVKDIRIEFDKILNQIDWMDAKTKAMAKKKANSIVDHIGYPPELLDDNKLEELYDGLQLGNLHYLENALNMTVFVANYAFSLLREKVNKTDWVRHGKPAIVNAFYSPLENSIQFPAGILQGIFFSSDRPRYMNYGAIGWVIGHEITHGFDDQGRQFDLEGIFIFFKNIDNIPFFLGNLVDWWHPTTKEQYLKKAKCIIEQYGNYFLPELNITLNGINTQGENIADNGGIKEAYRAYVNW-VDRNEEEKLLPGLNYSQKQLFWVSAANVWCAKFRPKALKLRVLTGVHSPDMFRVRGPFSNMPEFARDFNCPKGSHMNPAKRCEVW 794          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000007047 (supercontig:LSalAtl2s:LSalAtl2s3:1196101:1219563:1 gene:EMLSAG00000007047 transcript:EMLSAT00000007047 description:"maker-LSalAtl2s3-snap-gene-12.11")

HSP 1 Score: 504.212 bits (1297), Expect = 7.423e-170
Identity = 274/683 (40.12%), Postives = 379/683 (55.49%), Query Frame = 0

Query:   62 CLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEH-LVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKC 743
            C +  CI +AH L QNM+ +                  + I  +K+  + F+ + + +  + R+ILE   +  D   F + +S+Y+ CM+ED LE LG+ P+   L  L                                                  V+  DQ +LG++REYL++GFE  +V  YY +M + AVLLG +  +  T+LK+SLLFE++LAN S P+EERR+ +KLYN             P   ID ++ ++ G +     T  V  PK              R +ANYL WR+       LN+AAR++ L Y K +TG     PRWK C    G   T +       G +Y  ++F  +AK  ++ ++ Y++K F+ IL  I WMDE+TR  A  KL  I E IAYPEE++    ++ LYK L++  +    N  +L+LW   +  ++LRE + + DW      AVVNAFY+  +N I FPAGILQG FF+   P Y+N+G+IG VIGHEITHGFDDRGRQ D +GNL DWW  +TK +F+EK +CII QYG Y ++ +++ LNGV TQGENIADNGGLKEAY  Y  W+S HGQ E+ LPGL F+ +QLFW+S    WC+K+R + LK +I TG HSP  FR+ G  SN  EF+QDFKC  GT MNP  KC
Sbjct:   88 CTTPDCIASAHSLLQNMNPE------------------SRIADDKTYKSQFSIIGDELDEQIRDILESNGTENDSLVFNQVRSIYQACMNEDSLEGLGLEPMLKELKSL--------------------------------------------------VMGFDQASLGLSREYLVQGFESENVNYYYSYMQKVAVLLGASPEEAATQLKESLLFEMKLANASLPKEERRNASKLYN-------------PMKLID-VDDLMPGVNF----TDYVNEPK--------------RNVANYLLWRIASQGLFVLNKAAREISLEYRKNVTGTPADAPRWKKCVGAAGSLGTVV-------GHLYVSKYFKEDAKHNMMEMVKYIKKEFKKILQEITWMDEQTRTRAINKLAAIKEYIAYPEEIMKVENLEELYKGLKINNNTYFENEKSLSLWSYSYLWKKLREKIDKTDWKRHAEPAVVNAFYSSIENSIQFPAGILQGVFFNKNRPHYMNYGSIGWVIGHEITHGFDDRGRQSDSNGNLNDWWEMETKKKFLEKAQCIIWQYGNYTSKAVNVSLNGVNTQGENIADNGGLKEAYRAYVSWESVHGQ-ENSLPGLNFNSRQLFWLSAANNWCSKFRPKVLKNRILTGYHSPGAFRVRGTFSNLKEFSQDFKCPLGTNMNPINKC 662          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000006703 (supercontig:LSalAtl2s:LSalAtl2s372:146954:340151:1 gene:EMLSAG00000006703 transcript:EMLSAT00000006703 description:"maker-LSalAtl2s372-augustus-gene-3.13")

HSP 1 Score: 451.055 bits (1159), Expect = 9.328e-149
Identity = 237/691 (34.30%), Postives = 391/691 (56.58%), Query Frame = 0

Query:   58 KDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPE-SWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHV 745
            ++ +CL+  C+  +  L   MD  ADPC  F Q+ACG++ +  +IP ++S+ + F  +++ +    + +LEE  +  D +   K K+ YK+CM+  ++E +   PL   +  LGGWP + D  W  ++++   R I +  K       +  +V  D +NSS  +I +DQ   G+ +R+Y +    D D++ Y+ +M     LLG  +     + ++ + FE  +ANIS P  +R +   +Y K  L +++T    PE +W D+ ++++    I  +E I+  +  Y + +  ++  T+ ++I NY+ WR V  +   L       +  + + L GV     RW  C +          +  +  G+++   +F+ ++K   +++I  +R+AF D+L   +WMDE+TR  A++K + ++E I YPE + ++++++  Y+NL +   + + N+ N+  ++   +  +LR AV +  W  +   AVVNAFYNP +N I FPAGILQ  F+    P  LN+G IG VIGHEITHGFDD+GRQFD  GNL+ WW   T  +F    +CII QY  Y    I + +NG  TQGENIADNGGLK+A+  Y KW   +G+ E  LPGL  + KQLF++++ Q+WC   R E  K +I+   HSP   R++GPLSN  +FA+ + C  G++MNP++KC V
Sbjct:   66 ENKICLTQECVQTSAYLLGAMDTTADPCTXFFQYACGAWNRKHVIPEDRSSISTFEVMADQLQIILKGLLEEDHNEFDCEATLKVKNFYKSCMNISQIERISDTPLVQAINGLGGWPVV-DPYWTSHNWTIE-RVIGILKKNFTLGIFIEEWVGPDDRNSSAHIIQIDQMTFGLPSRDYFLLEESDRDLKAYHIYMTEVGALLGANKTYAYEQFQNVIRFEKSIANISVPEHDRINTGAIYTKISLKDLKTEV--PEINWNDYFDTVMGIGYIGDNEQIVSYSMPYFKLLGKLLKQTDKKIIHNYMIWRTVLELMPHLPPQYESTRAEFRRVLLGVLTGRIRWHKCVDWAN------KKMGMAVGALFIRDNFNYDSKEIALSMIHDIREAFNDLLEENEWMDEETRLVAKDKANSMNERIGYPEYITNKARLNQEYENLSITPVNFLDNLFNILRFEASNNQRKLRLAVDKDKW--QTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKFGNLKQWWNNRTIAEFHNAAQCIIDQYSTYMISDIQLNINGRMTQGENIADNGGLKQAFRAYNKWVRINGE-EDLLPGLNLTHKQLFFLNYAQIWCGSMRPEDAKTKIRAAVHSPGPIRVLGPLSNSVDFAEAYSCPKGSRMNPEQKCSV 743          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000000064 (supercontig:LSalAtl2s:LSalAtl2s100:449072:453177:1 gene:EMLSAG00000000064 transcript:EMLSAT00000000064 description:"maker-LSalAtl2s100-snap-gene-4.23")

HSP 1 Score: 418.698 bits (1075), Expect = 3.685e-137
Identity = 219/688 (31.83%), Postives = 363/688 (52.76%), Query Frame = 0

Query:   62 CLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPAL---TDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEHLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            C++ +C   A  +  NM+   DPC DF+QFACG F+  T+    +S    F+ +   +  + + +LE   +  D   F   ++ Y+ C++E  +E +G+ PL+  +L LGGW      +D S     ++W +   ++   G   + I+  ++  D  N SKR++ +D P  G+ R++L+KG  D +V+ Y+ +M  AAV LG     V+  L+  L FEI++AN++   +ER + T+LYN+  +  +  L      WI +INS +    + +++ IIV  P Y+  +  ++  T+ +V+ +Y+ WR +++    LN+AA+++   +N  L+G   +  R   C  +V       ++ E   G+MY    F   +K  + +++  +R+ F  IL N +W+ E+T++ A EK   + E+IAYP E L+ +K++ LY+ L        N+ NLT                                   F+NL   PAG+LQG FF    P YLN G +G +IGHEITHGFD  GRQ+  DG L +WW   T   F+ +++C ++QYG Y  + ++   NG  T  ENIADNGG++ AY  + +W++++ +    LPGL F+  QLFW+S   +WC+K   +  +  + T  HS    R+    SN + FA DF C   + MNP ++C VW
Sbjct:   27 CVTEACNDTAKTILFNMNKSVDPCDDFYQFACGGFVNKTVFRPGESRLNTFSEIRNLLKNQLKTLLEMNPTSNDIKPFVMVRNFYQACINETAMEMVGLKPLQETILSLGGWLDTEDKSDVSTKGTKYNWTSDLKILREYGYSTNFIMEFHIFQDLNNHSKRILLIDTPGFGIYRDFLVKGRGDFEVEAYFKYMKDAAVFLGHNLTDVQENLQSILNFEIQMANLTKSIDERINITELYNRMQIKNLTQLNPCI-PWIQYINSFLKITQVQKEDEIIVYEPAYISGLYRLMNKTSLKVVKDYVRWRFIESSLPELNKAAQNISNAFNDELSGTNGQKERDITCIEIVS------DKLEHAVGAMYVRTFFKESSKENIKDMVESVRQVFYKILNNTNWVGEETKRTALEKAHAMFEHIAYPSEYLNDTKLEELYQEL--------NLENLTY----------------------------------FKNLQILPAGVLQGLFFSADRPNYLNLGTMGWIIGHEITHGFDSNGRQYTKDGVLENWWDNQTVTNFLNRSQCFVEQYGNYSIKNVNQTNNGKRTLHENIADNGGIRAAYQAFIEWKNNNTKSIELLPGLNFTSNQLFWLSGANMWCSKNLKKVEESLVLTDEHSLATARVDLSFSNHEGFALDFSCPNDSPMNPPERCRVW 665          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000009818 (supercontig:LSalAtl2s:LSalAtl2s639:492787:496659:1 gene:EMLSAG00000009818 transcript:EMLSAT00000009818 description:"maker-LSalAtl2s639-augustus-gene-5.12")

HSP 1 Score: 386.341 bits (991), Expect = 2.410e-124
Identity = 228/694 (32.85%), Postives = 361/694 (52.02%), Query Frame = 0

Query:   59 DGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAE--NSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITGPSI--SRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE---HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHV 745
            + VC S  C   A  + +NMD   +PC DF+ F+CG FI  T++P  +      T   + +     +++ E ++ ++   FK  K+ YKTC+DE+K+EELG+ P+K +L ++GGWP +   SW++   ++ W+  T+ +   G      L+  V TD KN +KR+I LDQP +G ++ +L++ F +  + EY  +MV  A LLG TE + + E+     F+  L NIS       D+ +L   K L +++        W  +IN +I+  SI   ++E ++V    Y++ +  +I  T  RV ANY+ WRVV++   +LN+ A+D+   +   + G   +T R K C  +V           I   SMY  R+ +   K   V L TYL+  +   L+ + WMD++T+K AE K+ K+   I YP E+L   ++   Y+ LQ  E   H   N+L+L  + +  D   LR  V++  W + G +A+ N  Y    N     AGI++G  + +  P Y+NF  +  + GHEITH FD  GR  +  G   +WW+  T   F +K +C+I QY  YE    D  LNG       I ++               DH   E  LPGL ++ +QL+WIS   +WC+ +  E +  +I    HSPN++R+IGPLSN  EF++ F C   T MN  +KC +
Sbjct:   31 NKVCNSIGCQQTAKTILENMDSTVNPCDDFYAFSCGGFINKTIVPNGEEKVNVLTKTKDGLIRDINDLMNEELNSSELQIFKDLKTFYKTCIDENKIEELGVTPMKDILKQMGGWPVIECDSWSKPRQTYRWYNETLKLRKLGFSAKYFLNFLVETDIKNPNKRIIMLDQPYVGFSK-FLLQ-FGNDGIIEYIQYMVNMAXLLGATEEKARKEMLQVFEFQKSLMNISIKDPNLTDQYELMKVKDLRKLDGCI----DWQSYINGMISNSSIFVEKEEEVVVYGRSYIEKLKNLILKTPIRVQANYMLWRVVEDSLLYLNKEAQDIANNFVTPVFGYAPETDRTKVCYKIVE------ESIGIGMSSMYIRRYLAKIPKDLSVMLDTYLKNEYLKSLSEVSWMDDETKKRAEVKMRKMKILIGYPPELLSDVEMKKYYQGLQSLEKDKHFT-NMLSLMHYSKTKDYSLLRVPVTKNHWTKSGTIAIGNGAYRSLVNAYEIYAGIIRGIIYAEDRPKYINFALLAFIAGHEITHAFDVHGRTINEKGEEENWWSNATLTMFEDKKQCLINQYNNYEHSD-DTPLNGEFLLISAIKND---------------DHD--EDLLPGLNYTQEQLYWISSANLWCSVYNPEHIFNEI-FDDHSPNKYRVIGPLSNRPEFSKAFHCAANTPMNRTEKCQM 692          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000001658 (supercontig:LSalAtl2s:LSalAtl2s128:1881693:1892323:1 gene:EMLSAG00000001658 transcript:EMLSAT00000001658 description:"maker-LSalAtl2s128-snap-gene-19.19")

HSP 1 Score: 357.836 bits (917), Expect = 2.609e-117
Identity = 178/400 (44.50%), Postives = 247/400 (61.75%), Query Frame = 0

Query:  348 VIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEH-LVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            +I  T  RV AN+L W V+ +   +LNE AR +Q +Y + LTG K  + RWK C         + +R  I  GSMY  ++F  +AK+   ++++Y++K F  +L    W DE+T+  A +K+  + ENI YP E+L+ + +D LY+ L +GE     N+ +L  W   +   ++   +   DW +     VVNAFYNP  N I  PAGILQG+FF    P YLNFGAIG  IGHEITHGFDD GRQF+ +G+L DWW   TK +F+ KTKCII++YG +   +++  +NGV T GENIADNGGLK AY  Y  W +     E  LPGL F+ KQLFWIS   +WC K R + L+++I+   H+P  FR++G  SN  +FA+DF+C  G+ MNP+ KC VW
Sbjct:    2 LIRKTPIRVQANFLIWSVISSSMSYLNEEARHIQFKYIQKLTGAKTMSERWKTCV------GETKSRLGIHIGSMYVRQYFPEKAKTAAQSIVSYIKKEFEKLLRQNKWSDEETKAKALKKVKAMHENIGYPNEILNNTVIDILYEGLDLGESTYFENVHSLFKWTMDYVFLKIENEIKSYDWTDLVTPTVVNAFYNPLTNSINIPAGILQGNFFSLHRPNYLNFGAIGMAIGHEITHGFDDTGRQFNFEGDLFDWWNPSTKLKFINKTKCIIEEYGDFAYPKLNTTVNGVNTLGENIADNGGLKVAYRAYASWLNQTSFPEPLLPGLNFTEKQLFWISNANLWCTKIRGKTLEQKIRRDVHTPAMFRVLGAFSNMVKFAEDFQCPIGSPMNPKIKCEVW 395          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000006546 (supercontig:LSalAtl2s:LSalAtl2s358:80738:83514:1 gene:EMLSAG00000006546 transcript:EMLSAT00000006546 description:"maker-LSalAtl2s358-snap-gene-0.19")

HSP 1 Score: 362.073 bits (928), Expect = 6.772e-114
Identity = 236/773 (30.53%), Postives = 381/773 (49.29%), Query Frame = 0

Query:    1 MWAKVKIGVIAALVVIVVALAIALGISSGSSSPSRYYDDPDFVPVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDED-KLEELGMNPLKTLLL-ELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPD--VQEYYHFMVRAAVLL-----------GGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIIT--GPSISRDETIIVKNPKYLQDMAGVI-----YSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEHLVGNILNLTLWKRHF----DNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            M  KV +G +  LV++VV   +    S  + S                            VCL+  CI  +  +  +MD   DPC DF++FACG +  +  IP  KS+++ F  + E      +NIL E  +       +KA+  + +C DE  K+EE+   PL+ ++  ++ GW  + D S+  ++F +  +  L+  K        S  +  D  NSS+ VI LDQ  L +  +++ +K  E     ++     M R   LL              E  +K  + D   FE R+ANI+    +R+    LYN+  LG++  +  +  +W  ++N   +    +I  DE ++V  PKY + +  +I            + NY+ W+ +++M   L+++ RD  L   KA+ G +    RW+ C      D+ ++  + +  G+M+  + F  ++K+    +I  +++AF   L    WMD  T+  A +K   I + I YP+ +L+++ ++  YK L + E    +    TL    F      ++L + V+   W        VNA+Y P +N I FP+G+LQ  FF    P  LNFGA+G V+GHE++H FDD GR++D +GN+ DWW   T   F  K  C+ QQY  Y     +  ++G  T GENIADNGGLK +Y  Y KW  ++   E +LPG+  + +QLF+     VWC+    E    Q+    HSP +FR++GPLSNF EFA  F C P +KMNP+++C +W
Sbjct:   72 MGNKVFVGGVCTLVILVVIYFLTTKCSRSNKS----------------------------VCLTPDCIQISASILSSMDQDVDPCEDFYKFACGKWELSNPIPDGKSSWSPFEKLHEANQLVLKNILFEKNNTQISGAEEKARRYFYSCFDEGGKIEEVKGEPLRKIINNDMEGWIVM-DPSYNISNFDFQRKMYLLQNK-YHFGGFFSWSIVEDESNSSQHVIQLDQGGLSLPTQDFYVKDTEGNKRVIKALEIMMTRLFRLLLQEEYPNDPITKEGEDNIKQTVLDITNFEKRIANITISTSQRKQENNLYNRMTLGQL-NVNYNFMNWSIYVNEAFSQINKTIPEDEAVVVNAPKYFKALTDLINEHKATDNGKMTLNNYMIWQAIRDMKNTLSKSYRDTDLILQKAMFGKEGHEERWRSCIT----DTDAVIGYAL--GAMFVRKVFQGQSKTVAEGMINRIKEAFIANLNEAAWMDATTKARAVDKAHSITDMIGYPDYILNKNDLNKKYKGLNVSE---SDYFRNTLAHSQFVFVESLKKLFKKVNLTQW--SMTPPTVNAYYTPVKNQIVFPSGLLQNPFFALDYPKSLNFGAMGVVMGHELSHAFDDEGRKYDKNGNMVDWWLNSTTLNFKNKLTCMTQQYSHYTLH--NESVDGNITVGENIADNGGLKASYRAYTKWLEENTIPEVRLPGIKLNSRQLFF-----VWCSSSTKETDHFQLMEDHHSPGKFRVLGPLSNFKEFANVFLCSPYSKMNPKERCEIW 795          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000004915 (supercontig:LSalAtl2s:LSalAtl2s2594:1939:5295:-1 gene:EMLSAG00000004915 transcript:EMLSAT00000004915 description:"maker-LSalAtl2s2594-snap-gene-0.3")

HSP 1 Score: 333.954 bits (855), Expect = 4.539e-105
Identity = 213/701 (30.39%), Postives = 346/701 (49.36%), Query Frame = 0

Query:   78 MDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEHLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCII------------QQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDH-GQVE-------------------SQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            M+  ADPC DF+QFACG F+  T++ +++     F+ +S+ +    ++  +   +  D   F   ++LY+ C++E  +E  G+ PL+ ++ +LGGW    D          H     M  KG K                     Y    +L + RE         +++ Y+ +M  AAVLLG    +V+ +L++ L FEI++AN++  ++E++D + LYNK  +  + TL    + W+D+INS +    +  ++ +IV  P Y++++ G+++ ++  V+ +Y  WRV+++    LN AA+++   ++  L G   K      C  LV       N+ +   G+MY    F   +K  + ++I  +R     ILAN  W+ E+T+K+A +K   I  ++AYP E LD +K++ LYK L +                        +AV++ DW+  G   +VNAFY+   N +  PA ILQG  F    P YLN GAIG +IGHEITH  D   R+      L D          + K+K II            + +  Y  + ++  ++G  T GENIADNGG++EAY  Y +W++++ G +E                     LPGL F+  QLFW+S   +WC K R ++ +  IKT  HS    R+    SN ++F +DF     +KMNP KKC VW
Sbjct:    1 MNNSADPCDDFYQFACGGFLNKTVVKSDEIKVNTFSEISDRV--TLKHYWKXXSTTEDTKPFVLVRNLYRACINETAIETAGLEPLQKMISKLGGWLDTKDI---------HD----MLRKGKK---------------------YNWTTDLKLLRENXYSTNILLELKAYFQYMKDAAVLLGHNLTEVEGKLQNILDFEIKMANLTKSKDEKKDISVLYNKMQIKNLTTLNPCID-WLDYINSFLKTTQVQNEDNVIVSEPSYVKNLYGLMFDSSLEVVKDYARWRVIESSIPNLNAAAQNISEAFSNNLYGTSSKQSIEITCIQLVS------NKLKHAVGAMYVRDFFKESSKKNIKDMIHSIRLELYKILANATWLGEETKKNALDKAHAIFVHVAYPSEYLDDTKLEELYKGLDL------------------------DAVNKTDWVNNGKGVIVNAFYSGLNNALVLPAAILQGLVFSADRPNYLNLGAIGWIIGHEITH--DQLTRKIKCIFLLWD----RVNLSAISKSKTIIVFVFFHIYMLFKRHFFCY--KSVNKTIDGELTLGENIADNGGIREAYQAYLEWKNNNTGSIEILPGLNFTIEWKNNNTGSIEILPGLNFTSNQLFWLSGANMWCTKIRTKSEEMLIKTNPHSFPIARLDFSFSNNEDFVRDFNRPVDSKMNPSKKCRVW 626          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000000565 (supercontig:LSalAtl2s:LSalAtl2s1093:286030:293067:1 gene:EMLSAG00000000565 transcript:EMLSAT00000000565 description:"maker-LSalAtl2s1093-snap-gene-1.20")

HSP 1 Score: 323.939 bits (829), Expect = 4.124e-100
Identity = 205/715 (28.67%), Postives = 355/715 (49.65%), Query Frame = 0

Query:   62 CLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDT---FKKAKSLYKTCMDEDKLEELGMNPLKTLLLE---LGGWPAL-TDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQ---------------VKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGE-METLTGHPESWIDFINSIITGP-SISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQ--MGEHLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQI--DMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGL-GFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNP-QKKCHVW 746
            C +  C T+A  +   MD    PC DF++F CG ++K+   P  +S  + F  +S  I      ILE      D D     KKA+S YK+C++   + + G    KT+      LGG+P L + ++  E S       +L +     +  ++  YV  D +N+++ ++Y+DQ +LG+ R   +         E Y  +++A   L  + A+               +  +L+    FE  +A I  P ++RR+ T +YN   L + M++ T     W  + N ++ G  +I  ++ IIV  P Y + +  ++  T+ ++I NY+ WR++        +  R+    + K   G+K +  R   CA  V      +          Y  + F  ++K++V  ++  L+ +F++++A   WMD++T+  A+EK+D + +++ YP+ +  +S+++  YK L     + L+ NI       + ++N                               +TFPAGILQ  FF+ + P+      IG VIGHEITHGFDD+G Q+D +GNL  WW+  + + F ++ +CII+QY  +   +I  +  +NGV TQGEN  D GGL+E++  Y+KW + +   E +LP L  ++ +Q+F+I++ Q WC      +L+ QI +  HSP +FR  GP+SN   F++ F C+P   MN  +  C +W
Sbjct:   81 CTTEVCKTSAKSIISKMDVNVSPCEDFYEFTCGKYVKDNTNPDGQSDXSIFADLSNDIMTTTLEILEA----NDDDVPEVVKKARSYYKSCINMSSINDEGKKQYKTIFGSKGALGGYPILNSQWNLEEKSKELALGRVLYD---YNEGILIQSYVYLDAQNTAQHILYMDQASLGLLRINFVDS-------EKYKEIIKAYRTLQSSTAETLFKYLDINKPDDDKLNEDLESMFQFEKAIAGIMVPEDQRRNSTAMYNPMSLAKIMKSYTQI--KWKIYFNELLKGDNAIEENDKIIVAEPYYFEKLNELLNETDDKIIYNYIHWRILLQTLPNGPDEMREHYKTFLKDAMGIKKEVLRDNICAKRVAAPFDGMGGLGFAVAYEYIQKKFDDDSKNEVKKMVGGLKSSFKELVAESSWMDKETQNKAKEKVDSMVQSLGYPDWLKTESEIEKKYKELDELKPKTLLENI-------KKYNNAA----------------------------AVTFPAGILQYPFFESSNPI------IGVVIGHEITHGFDDQGSQYDNNGNLVKWWSNSSLEAFQKEKECIIEQYSAFNVPEISEETYVNGVLTQGENXXDXGGLRESFRAYKKWVNSNND-EPKLPELEKYTSEQMFFIAYSQTWCQVKTKASLQNQILSDPHSPGKFRSWGPVSNSKSFSKAFNCKPSDPMNNGENSCVLW 737          

BLAST of PREDICTED: neprilysin-2 vs. L. salmonis genes
Match: EMLSAG00000002013 (supercontig:LSalAtl2s:LSalAtl2s135:683680:686597:-1 gene:EMLSAG00000002013 transcript:EMLSAT00000002013 description:"maker-LSalAtl2s135-snap-gene-6.23")

HSP 1 Score: 276.944 bits (707), Expect = 1.217e-83
Identity = 154/463 (33.26%), Postives = 243/463 (52.48%), Query Frame = 0

Query:  289 ERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITGP--SISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQ-LPGL-GFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            E++    LYNK  +  +  L      W+D+IN  +T     ++  + IIV  P Y++++  V+ +T+ +V+ N++ W++V+N   +LN+ A  ++ +Y   + G      R   C         +    +   G+MY    F   +K  V  +I   R+ F  ++   DWM   T+  A EK   +  ++ YP E LD   +   Y  L++      GN   +  +   F  + L + V++  WI  G  AVVNA+Y+  +N + FPAG+LQG FF    P YLN G IG +IGHEI+HGFD+ G Q D DGNL +WW   T   + EK KC+  QYG Y    +++ ++G  T  ENIADN G++ AY  + KW++   +   + LPG   ++  Q FW+S    +C K   +  K++ +T  ++P  +RIIG  SN  EF+ DF C  G+KMN  +KC +W
Sbjct:  161 EQKSIADLYNKMSIKNLSNLNPCV-PWLDYINIFLTKELIQVNGSDEIIVTEPYYVRNLYNVMKNTSLKVVNNFVRWKIVQNSIPYLNKEASIIREKYISKIYGTSGPIDRSLICV------EEANKNLQNAVGAMYVRSFFKNGSKEDVEEMIGNTREVFYQMIIESDWMTNGTKASALEKALAMFNHVGYPAEYLDNDTLTERYNGLELNSLDYFGNKHRIWTFDLDFSIKSLNKRVNKTSWIYNGESAVVNAYYSTDENSLIFPAGMLQGMFFSVDRPTYLNLGGIGWIIGHEISHGFDNVGSQIDKDGNLFNWWDNVTAQIYEEKIKCLKYQYGNYTVESVNVTVDGEYTLEENIADNMGIRNAYLTFLKWKTSQTERNIEYLPGFDNYTINQAFWLSAANDYCIKMTSKTEKQRAETLPYAPEIYRIIGSFSNQPEFSSDFNCLAGSKMNRTEKCKLW 616          

HSP 2 Score: 88.1965 bits (217), Expect = 2.653e-18
Identity = 54/193 (27.98%), Postives = 96/193 (49.74%), Query Frame = 0

Query:   62 CLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKR---VIYLDQPNLGMAREYL-IKGFEDPDVQEYYH 250
            C + +C   A +L  N++   +PC DF+Q+ACG F+  T+IP  +      + ++  +  + + +LE   S  +   F  A++ YK+C++E ++E  G+ PLK +L +LGGW   T      +   +  R    N   L++  I   Y     KN S     V +LD  N+ + +E + + G ++  V E Y+
Sbjct:   26 CTTQACNDTAKKLLLNINPSINPCEDFYQYACGGFVNRTVIPPGRKGIDIASELTRKLNKQLKTVLEANSSSNEPGAFITARNFYKSCVNESQIEVQGLQPLKDILSKLGGWLNSTHNESNISGIKYDWR----NDANLEQKSIADLYNKMSIKNLSNLNPCVPWLDYINIFLTKELIQVNGSDEIIVTEPYY 214          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|1270743871|sp|A0A0B4K692.1|NEP2_DROME (RecName: Full=Neprilysin-2; Contains: RecName: Full=Neprilysin-2, soluble form)

HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0
Identity = 302/761 (39.68%), Postives = 460/761 (60.45%), Query Frame = 0

Query:    4 KVKIGVIAALVVIVVALAIALGISSG----SSSPSR------YYDDPDFVPVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSW-AENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIIT-GPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLV--GFDSTSLNRFE---IPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMG-EHLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            K++  ++ +L ++ V LA   G+  G    +S PS       + D      V  G  +  +  +   VCL+  CI  A  + + M  + +PC +F++FACG++++   IP +K + + F+ +S+ +  + ++I+      T+   F+    LYK CM++  +E LG  P+  +   LGGWP +   SW A++S++W  +       G     I+   +  D +NS+KR+I LDQ +L ++REYL+KGF +  V  YY +MV  AVL G      KTEL  SL FE+ LANIS P E+RR+ ++LYN +   +++    + + W+D++N+++  G +++ DE I +  P + +D+  ++  T  RVIANY+ WR+      FL+E  R  QL+Y  AL+G + +  RWK C ++     D    + F+   I  GS+Y  +HF  ++K+  + ++  +R  F DIL  ++WMD KT+K A+ KL  +  +I YP+EMLD  K+   Y  L +  +    + L + ++   +   +LR  V++ DW+     A+VNAFY+  +N I FPAGILQGHFF+   P Y+NFGAIG VIGHEITHGFDD+GRQFD  GNLRDWW  DT+  ++ K KCII+QYG Y  R   + LNG+ TQGENIADNGG+KE+Y  Y +W   HG  E++LPGL ++P+Q+FW++ GQ WCAK+R E+LK +I TG HSP+EFR++G LSN  +FA+DF C  G+ MNP +KC VW
Sbjct:   16 KLEKSLLVSLGIMFVVLATGFGLWIGKVLRTSPPSNPQATALHGDSTTINQVPTGTASKGKSGDSGDVCLTQECIHTASTVLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQ-WVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAKCIIEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAYRRWAEKHGP-EAKLPGLDYTPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEVW 774          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|74949025|sp|Q9W436.2|NEP_DROME (RecName: Full=Neprilysin-1)

HSP 1 Score: 507.679 bits (1306), Expect = 7.549e-168
Identity = 261/696 (37.50%), Postives = 409/696 (58.76%), Query Frame = 0

Query:   58 KDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQ--ILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPE-SWIDFINSIITGPSI--SRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQM-GEHLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            +D +C++  C+  A  L   MD  +DPC DF Q+ACG++ K   IP ++S+ + F  +S+      R +LEEPI   D     KAK+ +K+CMD  ++ ++G   LK +L  LGGWP + + +W+  +     R  LM    L  S+  ++  YV  D KNSS  ++ +DQ    + +R+Y +K     D + Y+ +M + A+LLG   A    EL+  +LFE +L N+S P  +R D + +Y K LL E++ L   PE  W +++ + + GP I    DE ++     YL +M  ++  T+ RV+ NY+ WR+V ++   + +  +  ++ + K L G++ +  RW  C            +  +  G+++   +F+ E+K   + +I  +R AF ++LA  DWMD++TR  A+EK D ++E I YPE + + ++++  Y NL +  ++ + N+L++  W+       LR+ V +  W      AVVNAFYNP +N I FPAGILQ  F+    P  LN+G IG VIGHEITHGFDD+GRQFD +GN+  WW   T + F E+T+C+I QY  Y+  ++DM ++G  TQGENIADNGGLK+A+  Y+KW++ HG+ E QLPGL  +  QLF++++ Q+WC   R E    +I++  HSP   R++GPLSN  +FA  +KC  G+ MNP +KC VW
Sbjct:  169 QDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVI-ERNWSPPADLSVER--LMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRAYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELV--PEVQWQEYLQAAL-GPGIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTN------KKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEP--AVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGR-EQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|74930356|sp|Q8IS64.1|ECE_LOCMI (RecName: Full=Endothelin-converting enzyme homolog; Short=ECE)

HSP 1 Score: 478.404 bits (1230), Expect = 4.403e-158
Identity = 265/707 (37.48%), Postives = 410/707 (57.99%), Query Frame = 0

Query:   56 YEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMD-EDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTI--LMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMARE--YLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPE--SWIDFINSIITGPS--ISRDETIIVKNPKYLQDMAGVIY----STNPRVIAN-YLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVA-VVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            + ++  C+S SC+TAA  +   MD  ADPC DF+Q+ACG +++   IP  KS +  F  + +      +N+LE+P+S    +  +KAK  Y +C+D  D +E LG  P+  LL+++GGW    +FS    S      T+    N  GL      +  V  D ++S K +I +DQ  L +     YL +  +D  +  Y  +M +  VLLGG E  V+T++K  + FE  LA I +P+E+RRD  KLYN     E++ + G P   +W  F ++ +   +  IS+ E ++V  P+YL+ +  +I     +T+ ++I N YL W+ V++M  +L++A RD      KAL G +     W++C      D+ ++  F I  G+M+    F   +K    N+I  +R AF+  L N+ WMD +TR+ AE+K D I + I +P+ +L+  ++D  YK+L++ E     N L +  +    + E+L + V++  W   G+    VNA+Y P +N I FPAGILQ  F+D   P  +N+GA+G V+GHE+TH FDD+GR++D +GNL  WW   T + F ++T+C++ QY  Y     +  +NG  T GENIADNGGLK AY+ Y +W+  + + E  LPGL FS KQLF++S+ QVWC+   DEA+K Q++   H+P +FR+IGPLSN  EF+ +F+C  G+KMNP  KC VW
Sbjct:   41 HAEEAYCVSMSCVTAAASVLSLMDATADPCSDFYQYACGGWVRANPIPDTKSMWGTFVKLEQQNQLVIKNVLEQPMSEFKSEAERKAKLYYMSCLDVNDTIETLGPKPMLDLLVKIGGWNITGNFSIKNWSLQKSLETLQNRYNMGGL-----FTWAVGEDDRDSKKHIIQIDQGGLTLPTRDNYLNETMDDKVLSAYLEYMTKIGVLLGGEEKNVRTQMKAVIEFETELAKIMSPQEDRRDEEKLYNNM---ELDKVQGRPPFINWHAFFSNAMENITRKISKKEKVVVYAPEYLEKLNDIIRNYTNTTDGKIILNNYLVWQTVRSMTSYLSKAFRDAYKGLRKALVGSEGGEKPWRYCVT----DTNNVIGFAI--GAMFVREAFHGNSKPAAENMINQIRTAFKSNLKNLKWMDAETRRAAEKKADAISDMIGFPDYILNPEELDKKYKDLEIKEDEYFENNLRVNKYNLKSNLEKLDQPVNKTRW---GMTPPTVNAYYTPTKNQIVFPAGILQAPFYDIGHPKSMNYGAMGVVMGHELTHAFDDQGREYDQNGNLHKWWNNQTIEAFKKRTQCVVDQYSNYTVD--NKHVNGKQTLGENIADNGGLKAAYHAYLEWEQRNPR-ELPLPGLNFSHKQLFFLSFAQVWCSASTDEAIKLQLEKDPHAPPKFRVIGPLSNLQEFSTEFRCPLGSKMNPVHKCEVW 727          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|114150028|sp|Q495T6.2|MMEL1_HUMAN (RecName: Full=Membrane metallo-endopeptidase-like 1; AltName: Full=Membrane metallo-endopeptidase-like 2; AltName: Full=NEP2(m); AltName: Full=Neprilysin II; Short=NEPII; AltName: Full=Neprilysin-2; Short=NEP2; Short=NL2; Contains: RecName: Full=Membrane metallo-endopeptidase-like 1, soluble form; AltName: Full=Neprilysin-2 secreted; Short=NEP2(s))

HSP 1 Score: 477.248 bits (1227), Expect = 5.987e-157
Identity = 271/709 (38.22%), Postives = 406/709 (57.26%), Query Frame = 0

Query:   57 EKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAEN-SFSWHA--RTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPDVQE-YYHFMVRAAVLL------GGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPE-SWIDFINSIITGPSISR--DETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQ--SKVDGLYKNLQMGEHLV--GNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQID-MRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            E   VC +  C+ AA ++ QNMD   +PC DF+QFACG +++  +IP   S Y+ F  + + +    + +LE   +  D    +KA++LY++CM++  +E+ G  PL  +L  +GGWP   D  W E     W    +  LMN++   +  ++  ++  D +NSS+ +IY+DQP LGM +REY   G  +  V+E Y  FMV  A LL            V+ ++   L  E +LA  + P+EER D   LY++  L E+++  G    +W  FI ++++   I    DE ++V    YLQ++  +I + + R I NYL WR+V +    L++  +D ++ Y KAL G  V+  RW+ C   VG+ ++++   E   GS+Y    F  ++KS V  LI  +R  F + L  + WMDE+++K A+EK   I E I +P+ +L++   ++D  Y NL   E L    ++ NL +  +     +LRE V    WI     AVVNAFY+P +N I FPAGILQ  FF    P  LNFG IG VIGHEITHGFDD GR FD +GN+ DWW+  +   F E+++C+I QYG Y     D   +NG  T GENIADNGG+++AY  Y KW ++ G+ + QLPGL  + +QLF+I++ QVWC  +R E   + IKT  HSP ++R++G L N   FA  F C  GT M+P+++C VW
Sbjct:   84 EVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTA-KDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMD-RWNETVGLEWELERQLALMNSQ-FNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWREC---VGYVNSNM---ENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR-SLRKLREKVDPNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGK-DQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|128062|sp|P08473.2|NEP_HUMAN (RecName: Full=Neprilysin; AltName: Full=Atriopeptidase; AltName: Full=Common acute lymphocytic leukemia antigen; Short=CALLA; AltName: Full=Enkephalinase; AltName: Full=Neutral endopeptidase 24.11; Short=NEP; Short=Neutral endopeptidase; AltName: Full=Skin fibroblast elastase; Short=SFE; AltName: CD_antigen=CD10)

HSP 1 Score: 470.315 bits (1209), Expect = 1.414e-154
Identity = 266/708 (37.57%), Postives = 396/708 (55.93%), Query Frame = 0

Query:   59 DGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTIL--MNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYL-IKGFEDPDVQEYYHFMVRAAVL------LGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMET-----LTGHPESWIDFINSIIT--GPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEML-DQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYE-ARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            DG+C SS CI +A +L QNMD   +PC DF ++ACG ++K  +IP   S Y  F  + + +    +++L+EP +  D    +KAK+LY++C++E  ++  G  PL  LL ++ GWP  T+    +   SW A   +  +N+K  KK  +++ +V TD KNS   VI++DQP LG+ +R+Y    G        Y  FM+  A L      L   E Q+  E+   +  E  +AN +A  E+R D   LYNK  L +++      + G P SW++F N I++    SI+ +E ++V  P+YL  +  ++   + R + N + WR + ++   L+   ++ +  + KAL G   +T  W+ CAN V          E   G +Y    F+ E+K  V +LI  +R+ F   L ++ WMD +T+K AEEK   I E I YP++++ + +K++  Y  L   E     NI+    + +    ++LRE V + +WI     AVVNAFY+  +N I FPAGILQ  FF       LN+G IG VIGHEITHGFDD GR F+ DG+L DWW Q +   F E+++C++ QYG +         LNG+ T GENIADNGGL +AY  Y+ +   +G+ E  LPGL  + KQLF++++ QVWC  +R E     IKT  HSP  FRIIG L N  EF++ F C   + MNP+KKC VW
Sbjct:   54 DGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKT-EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKV-LINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVN------GNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGE-EKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|1706563|sp|P42892.2|ECE1_HUMAN (RecName: Full=Endothelin-converting enzyme 1; Short=ECE-1)

HSP 1 Score: 469.544 bits (1207), Expect = 4.573e-154
Identity = 258/705 (36.60%), Postives = 397/705 (56.31%), Query Frame = 0

Query:   47 AGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPDV-QEYYHFMVRAAVLLGG-TEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKT-PRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEHL-VGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            A LG   Q      VCLS +C++    +  +MD   DPCHDF  +ACG +IK   +P   S +  F+ + E   A  +++LE   +    +  +KA+  Y+ CM+E ++EEL   PL  L+  LGGW       WA+++F     T+ +     + S   S YV+ D KNS+  VI +DQ  LG+ +R+Y +   E+  V   Y ++MV+   LLGG  E  ++ +++  L FE  LANI+ P+E+RRD   +Y+K    E++TL     +W+ F+N+I     I+  E I+V + +YL+ ++ +I +T+  ++ NY+ W +V+    FL++  +D   ++ + + G K    PRWKFC       S + N      G M+    F+ ++KS    +I  ++KAF + L+ + WMDE+TRK A+EK D I   I YP  ++D  ++D ++ +      L   N +    +      ++LR+A +R  W       +VNA+Y+P +N I FPAGILQ  F+  + P  LNFG IG V+GHE+TH FDD+GR++D DGNLR WW   + + F  +T+C+++QY  Y        +NG  T GENIADNGGLK AY  Y+ W   +G  E  LP LG +  QLF++ + QVWC+    E+  + + T  HSP+ FR+IG LSN  EF++ F+C PG+ MNP  KC VW
Sbjct:   85 AALGIQYQT-RSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASVS-EAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PWAKDNFQ---DTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTL-APAINWLPFLNTIFYPVEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCV------SDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQW--SMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNG-AEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|182702115|sp|Q5RE69.2|NEP_PONAB (RecName: Full=Neprilysin; AltName: Full=Atriopeptidase; AltName: Full=Enkephalinase; AltName: Full=Neutral endopeptidase 24.11; Short=NEP; Short=Neutral endopeptidase; AltName: Full=Skin fibroblast elastase; Short=SFE; AltName: CD_antigen=CD10)

HSP 1 Score: 468.774 bits (1205), Expect = 4.757e-154
Identity = 266/708 (37.57%), Postives = 396/708 (55.93%), Query Frame = 0

Query:   59 DGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTIL--MNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYL-IKGFEDPDVQEYYHFMVRAAVL------LGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMET-----LTGHPESWIDFINSIIT--GPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEML-DQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYE-ARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            DG+C SS CI +A +L QNMD  A+PC DF ++ACG ++K  +IP   S Y  F  + + +    +++L+EP +  D    +KAK+LY++C++E  ++  G  PL  LL ++ GWP  T+    +   SW A   +  +N+K  KK  +++ +V TD KNS   VI++DQP LG+ +R+Y    G        Y  FM+  A L      L   E Q+  E+   +  E  +AN +A  E+R D   LY K  L +++      + G P SW++F N I++    SI+ +E ++V  P+YL  +  ++   + R + N + WR + ++   L+   ++ +  + KAL G   +T  W+ CAN V          E   G +Y    F+ E+K  V +LI  +R+ F   L ++ WMD +T+K AEEK   I E I YP++++ + +K++  Y  L   E     NI+    + +    ++LRE V + +WI     AVVNAFY+  +N I FPAGILQ  FF       LN+G IG VIGHEITHGFDD GR F+ DG+L DWW Q +   F E+++C++ QYG +         LNG+ T GENIADNGGL +AY  Y+ +   +G+ E  LPGL  + KQLF++++ QVWC  +R E     IKT  HSP  FRIIG L N  EF++ F C   + MNP+KKC VW
Sbjct:   54 DGICKSSDCIKSAARLIQNMDATAEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKT-EDIVAVQKAKTLYRSCINESAIDSRGGEPLLKLLPDVYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKV-LINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYKKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVN------GNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGE-EKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|128065|sp|P07861.2|NEP_RAT (RecName: Full=Neprilysin; AltName: Full=Atriopeptidase; AltName: Full=Enkephalinase; AltName: Full=Neutral endopeptidase 24.11; Short=NEP; Short=Neutral endopeptidase; AltName: Full=Skin fibroblast elastase; Short=SFE; AltName: CD_antigen=CD10)

HSP 1 Score: 468.389 bits (1204), Expect = 7.153e-154
Identity = 264/709 (37.24%), Postives = 401/709 (56.56%), Query Frame = 0

Query:   59 DGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAEN-SFSWHARTIL--MNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYL-IKGFEDPDVQEYYHFMVRAAVL------LGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMET-----LTGHPESWIDFINSIITGPSIS--RDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEML-DQSKVDGLYKNLQMGEH-LVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYE-ARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            DG+C SS CI +A +L QNMD  A+PC DF ++ACG ++K  +IP   S Y+ F  + + +    +++L+EP +  D    +KAK+LY++C++E  ++  G  PL TLL ++ GWP  +  +W +    SW A   +  +N+K  KK  +++ +V TD KNS++ +I+ DQP LG+ +R+Y    G        Y  FM+  A L      L   E Q+  E+   +  E  +AN +   E+R D   LYNK  L +++      + G P SW +F N I++  +I+   +E ++V  P+YL  +  ++   +PR + N + WR + ++   L+   ++ +  + KAL G   +T  W+ CAN V          E   G +Y    F+ E+K  V +LI  +R+ F   L ++ WMD +T+K AEEK   I E I YP++++ +++K++  Y  L   E     NI+    + +    ++LRE V + +WI     AVVNAFY+  +N I FPAGILQ  FF       LN+G IG VIGHEITHGFDD GR F+ DG+L DWW Q + + F ++++C++ QYG +         LNG+ T GENIADNGG+ +AY  Y+ +   +G+ E  LPGL  + KQLF++++ QVWC  +R E     IKT  HSP  FRIIG L N  EFA  F C   + MNP++KC VW
Sbjct:   54 DGICKSSDCIKSAARLIQNMDASAEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEPKT-EDIVAVQKAKTLYRSCINESAIDSRGGQPLLTLLPDIYGWPVASQ-NWEQTYGTSWTAEKSIAQLNSKYGKKV-LINFFVGTDDKNSTQHIIHFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEQRLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEINGKPFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVN------GNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYKEEEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSARQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFTWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGE-EKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW 750          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|81918086|sp|Q4PZA2.1|ECE1_MOUSE (RecName: Full=Endothelin-converting enzyme 1; Short=ECE-1)

HSP 1 Score: 467.233 bits (1201), Expect = 3.676e-153
Identity = 266/750 (35.47%), Postives = 411/750 (54.80%), Query Frame = 0

Query:    2 WAKVKIGVIAALVVIVVALAIALGISSGSSSPSRYYDDPDFVPVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPDV-QEYYHFMVRAAVLLGG-TEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVK-VKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEHL-VGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            WA  +  V   LVV+V  LA  L                  V   A LG   Q      VCL+ +C++    +  +MD   DPC DF  +ACG +IK   +P   S +  F+ + E   A  +++LE   +    +  +KA+  Y+ CM+E ++EEL   PL  L+ +LGGW       WA+++F     T+ +     + S   S YV+ D KNS+  VI +DQ  LG+ +R+Y +   E+  V   Y ++MV+   LLGG  E  ++ +++  L FE  LANI+ P+E+RRD   +Y+K    E++TL     +W+ F+N+I     I+  E I+V + +YL+ ++ +I +T+  ++ NY+ W +V+    FL++  +D   ++ + + G K    PRWKFC       S + N      G M+    F+ ++K+    +I  ++KAF + L+ + WMDE+TR+ A+EK D I   I YP  ++D  ++D ++ +      L   N +    +      ++LR+A +R  W       +VNA+Y+P +N I FPAGILQ  F+  + P  LNFG IG V+GHE+TH FDD+GR++D DGNLR WW   + + F ++T+C++QQY  Y        +NG  T GENIADNGGLK AY  Y+ W   +G  E  LP LG +  QLF++ + QVWC+    E+  + + T  HSP+ FR+IG LSN  EF++ F+C PG+ MNP  KC VW
Sbjct:   58 WA-ARTSVEKRLVVLVTLLAAGL------------------VACLAALGIQYQT-RTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAVIKHLLENATASVS-EAERKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITG--PWAKDNFQ---DTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEDAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTL-APAINWLPFLNTIFYPVEINESEPIVVYDKEYLRQVSTLINNTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCIPRWKFCV------SDTENNLGFALGPMFVKATFAEDSKNIASEIIMEIKKAFEESLSTLKWMDEETRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQW--SMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNG-AEQTLPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPHHKCEVW 769          

BLAST of PREDICTED: neprilysin-2 vs. SwissProt
Match: gi|81906778|sp|Q9JLI3.1|MMEL1_MOUSE (RecName: Full=Membrane metallo-endopeptidase-like 1; AltName: Full=NEP2(m); AltName: Full=Neprilysin II; Short=NEPII; AltName: Full=Neprilysin-2; Short=NEP2; Short=NL2; AltName: Full=Neprilysin-like 1; Short=NL-1; AltName: Full=Neprilysin-like peptidase; Short=NEPLP; AltName: Full=Soluble secreted endopeptidase; Contains: RecName: Full=Membrane metallo-endopeptidase-like 1, soluble form; AltName: Full=Neprilysin-2 secreted; Short=NEP2(s))

HSP 1 Score: 467.233 bits (1201), Expect = 3.684e-153
Identity = 260/706 (36.83%), Postives = 402/706 (56.94%), Query Frame = 0

Query:   58 KDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAEN-SFSWH-ARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPDVQE-YYHFMVRAAVLL------GGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPE-SWIDFINSIITGPSISR--DETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSK--VDGLYKNLQMGEHL-VGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQID-MRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            K  +C + SC+ AA ++ +NMD   +PC +F+Q+ACG ++++ +IP   S Y+ F  + + +    + +LE+  S       +KAK+LY++CM++  +E+    PL ++L  +GGWP   D  W E     W   R + +      +  ++  ++  D +NSS+ VIY+DQP LGM +REY  +   +  V++ Y  FM   A +L          A V+ E+ + L  E  LAN + P+E+R D T LY++  L E++   G    +W  FI ++++   +    DE ++V    YL+++  +I S + R + NYL WR+V +    L++  ++ ++ Y KAL G  V+  RW+ C + V       +  E   GS+Y  R FS ++KS V  LI  +R  F D L  ++WMDE+++K A+EK   I E I YP+ +L+ +   +D  Y +L   E L   N L           ++LRE V +  WI     AVVNAFY+P +N I FPAGILQ  FF    P  LNFG IG VIGHEITHGFDD GR FD +GN+ DWW+  +   F ++++C+I QYG +     D   +NG +T GENIADNGG+++AY  Y +W +D G+ + +LPGL  +  QLF+I++ QVWC  +R E   + IKT  HSP ++R++G L N   F++ F C  G+ M+P K+C +W
Sbjct:   71 KSDICTTPSCVIAAARILENMDQSRNPCENFYQYACGGWLRHHVIPETNSRYSVFDILRDELEVILKGVLEDSTSQHR-PAVEKAKTLYRSCMNQSVIEKRDSEPLLSVLKMVGGWPVAMD-KWNETMGLKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQPTLGMPSREYYFQEDNNHKVRKAYLEFMTSVATMLRKDQNLSKESAMVREEMAEVLELETHLANATVPQEKRHDVTALYHRMDLMELQERFGLKGFNWTLFIQNVLSSVEVELFPDEEVVVYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKEARVDYRKALYGTTVEEVRWRECVSYVN------SNMESAVGSLYIKRAFSKDSKSTVRELIEKIRSVFVDNLDELNWMDEESKKKAQEKAMNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLKKLREKVDQNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSKDQPQSLNFGGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHFQQQSQCMIYQYGNFSWELADNQNVNGFSTLGENIADNGGVRQAYKAYLRWLADGGK-DQRLPGLNLTYAQLFFINYAQVWCGSYRPEFAVQSIKTDVHSPLKYRVLGSLQNLPGFSEAFHCPRGSPMHPMKRCRIW 765          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|1067094767|ref|XP_018009279.1| (PREDICTED: neprilysin-like isoform X2 [Hyalella azteca])

HSP 1 Score: 675.241 bits (1741), Expect = 0.000e+0
Identity = 330/743 (44.41%), Postives = 479/743 (64.47%), Query Frame = 0

Query:    7 IGVIAALVVIVVALAIALGISSGSSSPSRYYDDPDFVPVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITG-PSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            + ++A  + +++A+ +A+      SSP+  +         AG     Q     G+CL+  C+T+A +L +NMD Q DPC DF ++ACG+++K   IP EKS+ + F+ VS+ +  + R ++E   S  D  +    K LYK+CM+ +++ E G+ PLK +L E+GGWPA+  F+W  N F W     +    G     +    + T+ KNSS R+I +DQP+LGM +REYL++G  D DV+ Y  + V  A LLG      + EL +SLLFEI+LAN S P+E+RR+ TKLYNK  + E++    +   W+ +IN+I++   +++  E +IV  P Y++++  ++  T+ RVIANY+ WR+      +L+E ARD+QL Y+K +TG   + PRWK C   +G  S SL+      G +YA + F  +AK+    +++Y+R  F  IL  +DWMD++TR  A  K   I  +IAYPEE+LD++K+  LYK+LQ+ +  L+ N+ NLT++   +  +RLRE V + DW + G  AVVNAFY+P +N I FPAGILQG FF+   P YLN+GAIG VIGHEITHGFDD GRQFD  G+L++WW  +T+ +F++K+KCII QYG Y   ++ ++LNGV TQGENIADNGG+KEAYY Y ++ SDHG+ E+ LP LG + KQLFW+S   VWC K+R E LK +I TGAHSP  FR+ GPLSN  EF++D+ C+  +KMNP  KC VW
Sbjct:   43 LAMVAVSLFLLIAVCLAMAAVIAGSSPNSLF---------AG-----QTASASGICLTKGCVTSASELIENMDPQMDPCEDFFEYACGNYLKTKNIPDEKSSISQFSDVSDVLQEKLRTLVESEDSSEDTPSSLMVKQLYKSCMNTERIAEQGLQPLKDILREMGGWPAVEGFAWDRNRFDWVQNVYINRRLGYSVDLLFDFSITTNIKNSSWRIIDIDQPSLGMPSREYLLRGLNDSDVRAYLDYQVSLAALLGANRTAAELELTESLLFEIQLANFSLPKEQRRNATKLYNKMTVAELQGRVPNI-PWLSYINTILSPFTTVTEREEVIVNVPSYIENLGKLLLRTDKRVIANYMMWRLSAASISYLSEDARDLQLVYSKKITGTGKRKPRWKEC---MGAVSGSLS---YAVGKLYAEKFFKKDAKAAADEMVSYIRAEFDKILRTVDWMDDETRIRAINKSLAITPHIAYPEELLDETKLTELYKDLQISDGELLSNMRNLTIFGTDYSFKRLREKVDKNDWKKHGAAAVVNAFYSPLENSIQFPAGILQGTFFNADRPKYLNYGAIGFVIGHEITHGFDDMGRQFDYKGDLKEWWKPETRAKFIDKSKCIIYQYGNYTEPEVGLKLNGVNTQGENIADNGGIKEAYYAYNQYVSDHGE-ENPLPALGLTAKQLFWLSAANVWCGKYRPETLKLRILTGAHSPARFRVNGPLSNLPEFSRDWNCKSSSKMNPSHKCSVW 763          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|1067094765|ref|XP_018009278.1| (PREDICTED: neprilysin-like isoform X1 [Hyalella azteca])

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 322/696 (46.26%), Postives = 459/696 (65.95%), Query Frame = 0

Query:   54 QEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGM-AREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITG-PSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            Q     G+CL+  C+T+A +L +NMD Q DPC DF ++ACG+++K   IP EKS+ + F+ VS+ +  + R ++E   S  D  +    K LYK+CM+ +++ E G+ PLK +L E+GGWPA+  F+W  N F W     +    G     +    + T+ KNSS R+I +DQP+LGM +REYL++G  D DV+ Y  + V  A LLG      + EL +SLLFEI+LAN S P+E+RR+ TKLYNK  + E++    +   W+ +IN+I++   +++  E +IV  P Y++++  ++  T+ RVIANY+ WR+      +L+E ARD+QL Y+K +TG   + PRWK C   +G  S SL+      G +YA + F  +AK+    +++Y+R  F  IL  +DWMD++TR  A  K   I  +IAYPEE+LD++K+  LYK+LQ+ +  L+ N+ NLT++   +  +RLRE V + DW + G  AVVNAFY+P +N I FPAGILQG FF+   P YLN+GAIG VIGHEITHGFDD GRQFD  G+L++WW  +T+ +F++K+KCII QYG Y   ++ ++LNGV TQGENIADNGG+KEAYY Y ++ SDHG+ E+ LP LG + KQLFW+S   VWC K+R E LK +I TGAHSP  FR+ GPLSN  EF++D+ C+  +KMNP  KC VW
Sbjct:  311 QTASASGICLTKGCVTSASELIENMDPQMDPCEDFFEYACGNYLKTKNIPDEKSSISQFSDVSDVLQEKLRTLVESEDSSEDTPSSLMVKQLYKSCMNTERIAEQGLQPLKDILREMGGWPAVEGFAWDRNRFDWVQNVYINRRLGYSVDLLFDFSITTNIKNSSWRIIDIDQPSLGMPSREYLLRGLNDSDVRAYLDYQVSLAALLGANRTAAELELTESLLFEIQLANFSLPKEQRRNATKLYNKMTVAELQGRVPNI-PWLSYINTILSPFTTVTEREEVIVNVPSYIENLGKLLLRTDKRVIANYMMWRLSAASISYLSEDARDLQLVYSKKITGTGKRKPRWKEC---MGAVSGSLS---YAVGKLYAEKFFKKDAKAAADEMVSYIRAEFDKILRTVDWMDDETRIRAINKSLAITPHIAYPEELLDETKLTELYKDLQISDGELLSNMRNLTIFGTDYSFKRLREKVDKNDWKKHGAAAVVNAFYSPLENSIQFPAGILQGTFFNADRPKYLNYGAIGFVIGHEITHGFDDMGRQFDYKGDLKEWWKPETRAKFIDKSKCIIYQYGNYTEPEVGLKLNGVNTQGENIADNGGIKEAYYAYNQYVSDHGE-ENPLPALGLTAKQLFWLSAANVWCGKYRPETLKLRILTGAHSPARFRVNGPLSNLPEFSRDWNCKSSSKMNPSHKCSVW 998          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|193693010|ref|XP_001950596.1| (PREDICTED: neprilysin-11 [Acyrthosiphon pisum] >gi|641671283|ref|XP_008185529.1| PREDICTED: neprilysin-11 [Acyrthosiphon pisum])

HSP 1 Score: 672.159 bits (1733), Expect = 0.000e+0
Identity = 319/696 (45.83%), Postives = 453/696 (65.09%), Query Frame = 0

Query:   54 QEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEM-ETLTGHPESWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEH-LVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGL-GFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            +EYEKD +CL++ C+ AA  +  NMD   DPC DF+QFACG+FIK T+I  +K++ T F+ +S+++  + R I+ EPI   +   FK AK LYK+CMD++K+E+ G+ P+K +L  LGGWP L    W +  F+W          G      +   ++TD KN++ R I LDQ +LG++REYL+KG ++  V  YY +MV  AVL G    +   EL++SL FEI LA IS P EERRD  KLYN   + ++ +     P  W +++N +++  +I +D+ IIV +PKYL D+  ++ +T  R+ ANY+ WR       +L E  R  QL Y+  L+G   + PRWK C ++      S   F +  GS+Y  R+F   AK   + ++  +R+    IL +IDWMDE+TRK+A +K   +  +IAYP+E+LD SK++  Y+NL++ ++    +ILNLT +   +   +LR+ V++ DWI     A+VNAFY+  +N I FPAGILQG FF    P Y+N+GAIG VIGHEITHGFDD+GRQFD +GNL DWWA++TK +++EK  CII+QYG Y A ++ ++LNG+ TQGENIADNGG+KEAYY Y  W   HG VE +LPGL  ++P+Q+FW+S   VWC+K+R E LK +I TG HSP  FRIIGP SN ++F+ DF+C  G+ MNP KKC VW
Sbjct:   80 REYEKDNICLTTGCVKAAASVINNMDPTVDPCDDFYQFACGNFIKETIIDDDKTSQTTFSAISDSLLNKLRMIVTEPIQPNEQKPFKMAKLLYKSCMDKEKIEKEGLGPIKEMLKSLGGWPVLEADKWNDAEFTWKDSVYKFRVAGYSVDYFIDFSISTDLKNTTTRAIDLDQASLGLSREYLVKGTDEKIVAAYYRYMVDIAVLFGADRQRATKELRESLDFEIALAKISLPLEERRDAAKLYNPMKIADLQQKFPSIP--WQEYLNKLLSPLNIRQDDIIIVNSPKYLSDLEALLSNTPKRIQANYVIWRAAAASVSYLTEEMRKRQLDYSTELSGRTEREPRWKECVDI------SSGSFSLAIGSLYVRRYFDENAKKNALEMVNGIREEMYKILGSIDWMDEETRKNAIDKAKSMTSHIAYPDELLDDSKLNAFYENLEVNDNDYYTSILNLTKFGTDYSFSKLRQPVNKSDWITHSKTAIVNAFYSAIENSIQFPAGILQGAFFSSDRPRYMNYGAIGFVIGHEITHGFDDQGRQFDKEGNLVDWWAEETKKRYLEKASCIIRQYGNYTAHEVGLKLNGINTQGENIADNGGVKEAYYAYNVWTKRHG-VEPRLPGLQDYTPQQMFWVSAANVWCSKYRPETLKNRITTGFHSPGRFRIIGPFSNLEDFSNDFRCPLGSNMNPVKKCQVW 766          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|1229890582|ref|XP_022165694.1| (endothelin-converting enzyme homolog [Myzus persicae])

HSP 1 Score: 670.618 bits (1729), Expect = 0.000e+0
Identity = 318/696 (45.69%), Postives = 452/696 (64.94%), Query Frame = 0

Query:   54 QEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEM-ETLTGHPESWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEH-LVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGL-GFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            +EYEKD +CL++ C+ AA  +  NMD   DPC DF+QFACG+FIK T+I  +K++ T F+ +S+++  + R I+ EPI   +   FK AK LYK+CMD++K+E+ G+ P+K +L  LGGWP L    W +  F+W          G      +   ++TD KN++ R I LDQ +LG++REYL+KG +D  V  YY +MV  AVL G  + +   EL++SL FEI LA IS P EERRD  KLYN   + ++ +     P  W +++N ++   +I +D+ IIV +PKYL D+  ++ +T  R+ ANY+ WR       +L E  R  QL Y+  L+G   + PRWK C ++      S   F +  GS+Y  R F   AK   + ++  +R+    IL++IDWMD++TRK+A +K   +  +IAYP+E+LD SK++  Y+NL++ ++    ++LNLT +   +   +LR+ V++ DWI     A+VNAFY+  +N I FPAGILQG FF    P Y+N+GAIG VIGHEITHGFDD+GRQFD  GNL DWWA++TK +++EK  CII+QYG Y A ++ ++LNG+ TQGENIADNGG+KEAYY Y  W   HG VE +LPGL  ++P+Q+FW+S   VWC+K+R E LK +I TG HSP  FRIIGP SN ++F+ DF+C  G+ MNP KKC VW
Sbjct:   80 REYEKDNICLTTGCVKAAASVINNMDPSVDPCDDFYQFACGNFIKETIIDDDKTSQTTFSAISDSLLNKLRMIVTEPIQQDEQKPFKMAKLLYKSCMDKEKIEKEGLGPIKEMLKSLGGWPVLEADKWNDADFTWKDSVYRFRKAGYSVDYFIDFSISTDLKNTTMRAIDLDQASLGLSREYLVKGTDDKIVAAYYRYMVDIAVLFGADKQRATKELRESLDFEIGLAKISLPLEERRDAAKLYNPMKIADLQQKFPSIP--WQEYLNKLLNPLTIRQDDIIIVNSPKYLSDLEAILSNTPKRIQANYVIWRAAAASVSYLTEEMRKRQLEYSTELSGRTEREPRWKECVDI------SSGSFSLAIGSLYVRRFFDENAKKNALEMVNGIREEMYKILSSIDWMDDETRKNAIDKAKSMTSHIAYPDELLDDSKLNAFYENLEVNDNDYYTSVLNLTKFGTDYSFSKLRQPVNKSDWITHSKTAIVNAFYSAIENSIQFPAGILQGAFFSSDRPRYMNYGAIGFVIGHEITHGFDDQGRQFDKQGNLVDWWAEETKKRYLEKASCIIRQYGNYTAHEVGLKLNGINTQGENIADNGGVKEAYYAYNVWTKRHG-VEPRLPGLQDYTPQQMFWVSAANVWCSKYRPETLKNRITTGFHSPGRFRIIGPFSNLEDFSNDFRCPLGSNMNPVKKCQVW 766          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|345492449|ref|XP_001600059.2| (PREDICTED: neprilysin-11-like isoform X4 [Nasonia vitripennis])

HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0
Identity = 324/748 (43.32%), Postives = 482/748 (64.44%), Query Frame = 0

Query:    7 IGVIAALVVIV-VALAIALGISSGSSSP--SRYYDDPDFV--PVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSII-TGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQM--GEHLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            + +IA   V+V +ALAI LG+ + ++ P  S        +  P+   +    ++  +  +CLS  CI  A  + +NMD   +PC DF++FACGSF+KNT+IP +K++   F+ +S+ +  + R+ +EE     D   F+  K+LYKTCM++  +EE G+NPL  +L ELGGWP L    W++  F+W         KG      +   +  D KNS+KRVI LDQ +LG++REYL KG +D  V  YY++MV  A +LG    Q K ELK+SL FEI+LANIS P E+RR+ T LYN   + ++ T       W+++ ++++ +  +++ DE +IV  P ++ D+  ++  T  R+ ANY+ WR       +LN+  R  QL Y+  ++G   + PRWK C ++V         F I  G++Y  ++F+ +AK   V +++ +R  F+ IL  +DWMD++TRK A +K D +  +IAYP+E+LD +K++  Y+ L++  G +L  +ILNLTL+   +  E+LR+ V++ DW+  G  A+VNAFY+  +N I FPAGILQG FF +  P Y+N+GAIG V+GHEITHGFDD+GRQFD +GNL +WWA +TK++++++ +CII QYG Y A ++ + LNG+ TQGENIADNGG+KEAY  Y +W   +G  E +LPGL +S +Q+FWIS    WC+K+R E LK +I TG HSP EFR++GPLSN DEFA+DFKC  G++MNP+KKC VW
Sbjct:   26 LTIIAVCSVLVAIALAIGLGVLARNAEPCESSLMSAEALIGAPLAKKVPQVVEKSPEGDICLSPGCIHTASSILENMDQNVEPCDDFYRFACGSFLKNTIIPDDKTSVNTFSIISDKLQKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKILKELGGWPVLVGDKWSDGDFNWKESVYKFGKKGYSVDYFIDFSIGVDLKNSTKRVIDLDQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQAKIELKESLEFEIKLANISLPSEKRRNATALYNPMTVRQL-TQKFPTIPWLEYFSTLLPSSITVTEDEMVIVNVPSFITDLEKLLEQTPKRIQANYVMWRAAATSVSYLNDEIRKRQLAYSTVISGRTEREPRWKECVDIVS------GSFSISVGALYVRKYFNEDAKKNAVEMVSNIRGEFKKILDQVDWMDDETRKAALDKADSMSTHIAYPDELLDDTKLEQFYEKLEITPGNYL-ESILNLTLFGTQYSFEKLRKPVNKSDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSNDRPKYMNYGAIGFVMGHEITHGFDDQGRQFDKNGNLVEWWAAETKEKYLKRAQCIINQYGNYTAPEVSLNLNGINTQGENIADNGGIKEAYLAYNEWVRRNG-AEPRLPGLDYSGQQMFWISAANTWCSKYRPETLKLRITTGVHSPGEFRVLGPLSNMDEFAKDFKCPVGSRMNPEKKCAVW 764          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|972184594|ref|XP_015173767.1| (PREDICTED: membrane metallo-endopeptidase-like 1 isoform X3 [Polistes dominula])

HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0
Identity = 318/737 (43.15%), Postives = 475/737 (64.45%), Query Frame = 0

Query:   14 VVIVVALAIALGISSGSSSPSRYYDDPDFVPVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEM-ETLTGHPESWIDFINSIITGPSISRD--ETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            V++ +ALA+ALG+ + +++  +   + + + V  G   + Q  EK  +C+S  C+  A ++ +NMD   +PC DF+QFACG F+K+T+IP +K++   F+ +S+ +  + R  +EE     +   F  AK  YKTCM++  +EE G+ PL  +L  LGGWP L   +W E  F+W         KG      +   +  D KNS+ R+I LDQ +LG++REYL KGF+D  VQ YY +MV  AV+LG  + + KTELK+SL FE++LANIS P E+RR+ T LYN   + E+ +     P  W ++ N+I+  P++  D  E +IV  P Y+  +  ++  T  R+ ANY+ WR       +L E  R  QL+Y+ AL+G   +  RWK C ++V   S SL+   I  G+MY  ++F  +AK   + +++ +R+ F+ IL  +DWMDE T++ A +K + +  +IAYP+E+LD  K++  YK L++ +   + +ILNLTL+   +   +LR+ V++ DW+  G  A+VNAFY+  +N I FPAGILQG FF++  P Y+N+GAIG VIGHEITHGFDD+GRQFD +GNL DWWA +TK+ ++E+ +CI+ QYG Y   ++ + LNG+ TQGENIADNGG+KEAY+ Y++W       E +LPGL ++P+Q+FWIS    WC+K+R EA+K +I TG HSP EFR++GP SN +EF++DF C  G+KMNP+KKC VW
Sbjct:   34 VLLCIALAVALGVLAANTASCKQSSNAEALQVIKGTTINRQSTEKQNICVSPGCVHTASKILENMDSDVEPCDDFYQFACGGFLKSTIIPDDKTSVNTFSIISDNLQQQLRTSIEEKSPPNEPKPFTLAKIFYKTCMNKTAIEERGLEPLHNILKTLGGWPVLEGDNWKEEDFNWIDSVYKFRTKGYSVDYFIDFSIGVDLKNSTMRIIDLDQASLGLSREYLSKGFDDKIVQAYYDYMVDIAVILGADKNRAKTELKESLEFEMKLANISLPNEKRRNATLLYNPMTITELNKNFPSIP--WKEYFNTIL-APTVQVDENEVVIVSVPSYITSLEELLSKTPKRIQANYVMWRAAAGSVSYLTENIRRRQLQYSTALSGKTEREARWKECVDIV---SGSLS---ISVGAMYVRKYFKEDAKKNAIEMVSDIREEFKKILKKVDWMDENTKESALDKAESMSSHIAYPDELLDDKKLEEFYKKLELTDGSYLESILNLTLFGTEYSFSKLRKPVNKSDWVTHGRPAIVNAFYSSIENSIQFPAGILQGTFFNNDRPRYMNYGAIGFVIGHEITHGFDDQGRQFDKEGNLVDWWAPETKENYLERAECIVHQYGNYTVEEVGLNLNGINTQGENIADNGGIKEAYFAYKEW-VKRNHPEPKLPGLSYTPEQMFWISAANTWCSKYRPEAMKLRITTGFHSPGEFRVLGPFSNMNEFSKDFNCPLGSKMNPEKKCAVW 760          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|644996757|ref|XP_008208160.1| (PREDICTED: membrane metallo-endopeptidase-like 1 isoform X2 [Nasonia vitripennis])

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 324/748 (43.32%), Postives = 482/748 (64.44%), Query Frame = 0

Query:    7 IGVIAALVVIV-VALAIALGISSGSSSP--SRYYDDPDFV--PVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSII-TGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQM--GEHLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            + +IA   V+V +ALAI LG+ + ++ P  S        +  P+   +    ++  +  +CLS  CI  A  + +NMD   +PC DF++FACGSF+KNT+IP +K++   F+ +S+ +  + R+ +EE     D   F+  K+LYKTCM++  +EE G+NPL  +L ELGGWP L    W++  F+W         KG      +   +  D KNS+KRVI LDQ +LG++REYL KG +D  V  YY++MV  A +LG    Q K ELK+SL FEI+LANIS P E+RR+ T LYN   + ++ T       W+++ ++++ +  +++ DE +IV  P ++ D+  ++  T  R+ ANY+ WR       +LN+  R  QL Y+  ++G   + PRWK C ++V         F I  G++Y  ++F+ +AK   V +++ +R  F+ IL  +DWMD++TRK A +K D +  +IAYP+E+LD +K++  Y+ L++  G +L  +ILNLTL+   +  E+LR+ V++ DW+  G  A+VNAFY+  +N I FPAGILQG FF +  P Y+N+GAIG V+GHEITHGFDD+GRQFD +GNL +WWA +TK++++++ +CII QYG Y A ++ + LNG+ TQGENIADNGG+KEAY  Y +W   +G  E +LPGL +S +Q+FWIS    WC+K+R E LK +I TG HSP EFR++GPLSN DEFA+DFKC  G++MNP+KKC VW
Sbjct:   81 LTIIAVCSVLVAIALAIGLGVLARNAEPCESSLMSAEALIGAPLAKKVPQVVEKSPEGDICLSPGCIHTASSILENMDQNVEPCDDFYRFACGSFLKNTIIPDDKTSVNTFSIISDKLQKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKILKELGGWPVLVGDKWSDGDFNWKESVYKFGKKGYSVDYFIDFSIGVDLKNSTKRVIDLDQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQAKIELKESLEFEIKLANISLPSEKRRNATALYNPMTVRQL-TQKFPTIPWLEYFSTLLPSSITVTEDEMVIVNVPSFITDLEKLLEQTPKRIQANYVMWRAAATSVSYLNDEIRKRQLAYSTVISGRTEREPRWKECVDIVS------GSFSISVGALYVRKYFNEDAKKNAVEMVSNIRGEFKKILDQVDWMDDETRKAALDKADSMSTHIAYPDELLDDTKLEQFYEKLEITPGNYL-ESILNLTLFGTQYSFEKLRKPVNKSDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSNDRPKYMNYGAIGFVMGHEITHGFDDQGRQFDKNGNLVEWWAAETKEKYLKRAQCIINQYGNYTAPEVSLNLNGINTQGENIADNGGIKEAYLAYNEWVRRNG-AEPRLPGLDYSGQQMFWISAANTWCSKYRPETLKLRITTGVHSPGEFRVLGPLSNMDEFAKDFKCPVGSRMNPEKKCAVW 819          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|985418566|ref|XP_015374746.1| (PREDICTED: neprilysin-11 [Diuraphis noxia])

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 318/696 (45.69%), Postives = 451/696 (64.80%), Query Frame = 0

Query:   54 QEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEM-ETLTGHPESWIDFINSIITGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGEH-LVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGL-GFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            +EYEKD +CL++ C+ AA  +  NMD   DPC DF+QFACG+FIK T+I  +K++ T F+ +S+++  + R I+ EPI   +   FK AK LYK+CMD++K+E+ G+ P+K +L  LGGWP L    W +  F+W          G      +   ++TD KN++ R I LDQ +LG++REYL+KG +D  V  YY +MV  AVL G    +   EL++SL FEI LA IS P EERRD  KLYN   + ++ +     P  W +++N ++   +I +D+ IIV +PKYL D+  ++ +T  R+ ANY+ WR       +L E  R  QL Y+  L+G   + PRWK C ++      S   F +  GS+Y  R F   AK   + ++  +R+    IL +IDWMD++TRK+A +K   +  +IAYP+E+LD SK++  Y+NL++ ++    ++LNLT +   +   +LR+ V++ DWI     A+VNAFY+  +N I FPAGILQG FF    P Y+N+GAIG VIGHEITHGFDD+GRQFD  GNL DWWA++TK +++EK  CII+QYG Y A+++ ++LNG+ TQGENIADNGG+KEAYY Y  W   +G VE +LPGL  ++P+Q+FWIS   VWC+K+R E LK +I TG HSP  FRIIGP SN ++F+ DF+C  G+ MNP KKC VW
Sbjct:   80 REYEKDNICLTTGCVKAAASVINNMDSSVDPCDDFYQFACGNFIKETIIDDDKTSQTTFSSISDSLLNKLRMIITEPIQPNEQKPFKMAKLLYKSCMDKEKIEKQGLGPIKEMLKSLGGWPVLEADKWNDADFTWKDSVYKFRLAGYSVDYFIDFSISTDLKNTTMRAIDLDQASLGLSREYLVKGTDDKIVAAYYRYMVDIAVLFGAERQRATKELRESLDFEIGLAKISLPLEERRDAAKLYNPMKIADLQQKFPSIP--WQEYLNKLLNPLTIRQDDIIIVNSPKYLSDLEALLSNTPKRIQANYVIWRAAAASVSYLTEEMRKRQLEYSTELSGRTEREPRWKECVDI------SSGSFSLAIGSLYVRRFFDENAKKNALEMVNGIREEMYKILTSIDWMDDETRKNAIDKAKSMTSHIAYPDELLDDSKLNAFYENLEVNDNDYYTSVLNLTKFGTDYSFSKLRQPVNKSDWITHSKTAIVNAFYSAIENSIQFPAGILQGAFFSSDRPRYMNYGAIGFVIGHEITHGFDDQGRQFDKQGNLVDWWAEETKKRYLEKALCIIKQYGNYTAQEVGLKLNGINTQGENIADNGGVKEAYYAYNVWTKRNG-VEPRLPGLQDYTPQQMFWISAANVWCSKYRPETLKNRITTGFHSPGRFRIIGPFSNLEDFSHDFRCPLGSNMNPVKKCQVW 766          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|1067094761|ref|XP_018009276.1| (PREDICTED: neprilysin-like [Hyalella azteca])

HSP 1 Score: 666.766 bits (1719), Expect = 0.000e+0
Identity = 324/710 (45.63%), Postives = 458/710 (64.51%), Query Frame = 0

Query:   39 DPDFVPVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSIITG-PSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQMGE-HLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            DP  + V +   +  Q       CL+ SCIT+A +L  NMD Q DPC DF ++ACG++IK+  IP EKS+ T F+ VS+ +  + R ++E   S  D  +    K LYK+CM+ +++ E G+ PLK +L E+GGWPA+   +W  N F W     +    G     +L   V T+ KNS+ R+I +DQP+ GM+REYL++G  D DV+ Y  + V  A LLG      + EL +SLLFEI+LAN S P E+RR+ ++LYNK  + E++    +   W+ +IN+++    +I+ DE +IV  P YL+++  ++  T  RVIAN+L WR       +L+E ARD+QL Y+K +TG   + PRWK C   +G  S SL+        +YA + F  +AK+    +++Y+R+ F  IL  +DWMD++TR  A  K   I  +IAYP+E+LD+SK+  +YK+LQ+ +  L+ N+ NLT++   +  +RLRE + + DW   G  AVVNA+Y+   N I FPAGILQG FF+   P YLNFG+IG VIGHEITHGFDD GRQFD  G+L++WW  +TK +F+EK+KCII QYG Y A ++ ++LNGV TQGENIADNGG+KEAYY Y ++ SDHG+ E+ LP LG + KQLFW+S   VWC K+R E+LK  I TGAHSP  FR+ G LSN  EF++D+ C+  +KMNP +KC VW
Sbjct:  306 DPSELSVVSCKASGGQTSSTSEFCLTKSCITSASELIANMDSQVDPCEDFFEYACGNYIKSRNIPDEKSSITQFSDVSDVLQEKLRMLIESEDSSEDTPSGLMVKQLYKSCMNTERIAEQGLQPLKDILREMGGWPAVEGAAWGHNRFDWVQNVYINRRLGYSVDYLLDFSVTTNIKNSTWRIIDIDQPSFGMSREYLMRGLNDSDVRAYLDYQVSLAALLGANRTAAQLELTESLLFEIQLANFSLPNEKRRNASELYNKMTVAELQARVPNI-PWLSYINTLLAPFTNITEDEEVIVNVPSYLENLDKLLLKTPKRVIANFLMWRASAASISYLSEDARDLQLEYSKKITGTGKRNPRWKEC---IGAVSGSLS---YAVSKLYAEKFFKKDAKAAADEMVSYVRREFDKILRAVDWMDDETRLRAINKSQAITSHIAYPDELLDESKIAEVYKDLQISDGELLSNMRNLTIYSADYSFKRLREVIDKNDWKRHGTAAVVNAYYSRVDNSINFPAGILQGTFFNAERPKYLNFGSIGFVIGHEITHGFDDVGRQFDYKGDLKEWWEPETKAKFIEKSKCIIHQYGNYTAPEVGLKLNGVNTQGENIADNGGIKEAYYAYNQYVSDHGE-ENPLPALGLTAKQLFWLSAANVWCGKYRPESLKFLILTGAHSPVRFRVNGELSNSPEFSRDWNCKLNSKMNPSQKCSVW 1007          

BLAST of PREDICTED: neprilysin-2 vs. nr
Match: gi|644996760|ref|XP_008208161.1| (PREDICTED: neprilysin-11-like isoform X3 [Nasonia vitripennis])

HSP 1 Score: 666.766 bits (1719), Expect = 0.000e+0
Identity = 327/759 (43.08%), Postives = 483/759 (63.64%), Query Frame = 0

Query:    7 IGVIAALVVIV-VALAIALGI---------SSGSSSPSRYYDDPDFV------PVHAGLGTDTQEYEKDGVCLSSSCITAAHQLFQNMDFQADPCHDFHQFACGSFIKNTMIPAEKSTYTGFTPVSETIYARARNILEEPISYTDWDTFKKAKSLYKTCMDEDKLEELGMNPLKTLLLELGGWPALTDFSWAENSFSWHARTILMNAKGLKKSQILSCYVATDYKNSSKRVIYLDQPNLGMAREYLIKGFEDPDVQEYYHFMVRAAVLLGGTEAQVKTELKDSLLFEIRLANISAPREERRDRTKLYNKKLLGEMETLTGHPESWIDFINSII-TGPSISRDETIIVKNPKYLQDMAGVIYSTNPRVIANYLGWRVVKNMFQFLNEAARDVQLRYNKALTGVKVKTPRWKFCANLVGFDSTSLNRFEIPAGSMYAMRHFSPEAKSKVVNLITYLRKAFRDILANIDWMDEKTRKHAEEKLDKIDENIAYPEEMLDQSKVDGLYKNLQM--GEHLVGNILNLTLWKRHFDNERLREAVSRRDWIERGIVAVVNAFYNPFQNLITFPAGILQGHFFDDTVPMYLNFGAIGAVIGHEITHGFDDRGRQFDGDGNLRDWWAQDTKDQFVEKTKCIIQQYGGYEARQIDMRLNGVTTQGENIADNGGLKEAYYGYEKWQSDHGQVESQLPGLGFSPKQLFWISWGQVWCAKWRDEALKKQIKTGAHSPNEFRIIGPLSNFDEFAQDFKCEPGTKMNPQKKCHVW 746
            + +IA   V+V +ALAI LG+         SS  S+P+     P         P+   +    ++  +  +CLS  CI  A  + +NMD   +PC DF++FACGSF+KNT+IP +K++   F+ +S+ +  + R+ +EE     D   F+  K+LYKTCM++  +EE G+NPL  +L ELGGWP L    W++  F+W         KG      +   +  D KNS+KRVI LDQ +LG++REYL KG +D  V  YY++MV  A +LG    Q K ELK+SL FEI+LANIS P E+RR+ T LYN   + ++ T       W+++ ++++ +  +++ DE +IV  P ++ D+  ++  T  R+ ANY+ WR       +LN+  R  QL Y+  ++G   + PRWK C ++V         F I  G++Y  ++F+ +AK   V +++ +R  F+ IL  +DWMD++TRK A +K D +  +IAYP+E+LD +K++  Y+ L++  G +L  +ILNLTL+   +  E+LR+ V++ DW+  G  A+VNAFY+  +N I FPAGILQG FF +  P Y+N+GAIG V+GHEITHGFDD+GRQFD +GNL +WWA +TK++++++ +CII QYG Y A ++ + LNG+ TQGENIADNGG+KEAY  Y +W   +G  E +LPGL +S +Q+FWIS    WC+K+R E LK +I TG HSP EFR++GPLSN DEFA+DFKC  G++MNP+KKC VW
Sbjct:   26 LTIIAVCSVLVAIALAIGLGVLARNAEPCESSLMSAPANAEMLPSTAEALIGAPLAKKVPQVVEKSPEGDICLSPGCIHTASSILENMDQNVEPCDDFYRFACGSFLKNTIIPDDKTSVNTFSIISDKLQKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKILKELGGWPVLVGDKWSDGDFNWKESVYKFGKKGYSVDYFIDFSIGVDLKNSTKRVIDLDQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQAKIELKESLEFEIKLANISLPSEKRRNATALYNPMTVRQL-TQKFPTIPWLEYFSTLLPSSITVTEDEMVIVNVPSFITDLEKLLEQTPKRIQANYVMWRAAATSVSYLNDEIRKRQLAYSTVISGRTEREPRWKECVDIVS------GSFSISVGALYVRKYFNEDAKKNAVEMVSNIRGEFKKILDQVDWMDDETRKAALDKADSMSTHIAYPDELLDDTKLEQFYEKLEITPGNYL-ESILNLTLFGTQYSFEKLRKPVNKSDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSNDRPKYMNYGAIGFVMGHEITHGFDDQGRQFDKNGNLVEWWAAETKEKYLKRAQCIINQYGNYTAPEVSLNLNGINTQGENIADNGGIKEAYLAYNEWVRRNG-AEPRLPGLDYSGQQMFWISAANTWCSKYRPETLKLRITTGVHSPGEFRVLGPLSNMDEFAKDFKCPVGSRMNPEKKCAVW 775