multidrug resistance-associated protein 4, snap_masked-scaffold438_size171652-processed-gene-0.1 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000000752 (supercontig:LSalAtl2s:LSalAtl2s111:55855:93761:1 gene:EMLSAG00000000752 transcript:EMLSAT00000000752 description:"maker-LSalAtl2s111-augustus-gene-1.10") HSP 1 Score: 1043.88 bits (2698), Expect = 0.000e+0 Identity = 581/1349 (43.07%), Postives = 818/1349 (60.64%), Query Frame = 0
Query: 21 SIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWD---SQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGE-RDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKK-GSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQ----------MYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIAR 1354
+I F W P +R G K++ +++DL++ LR D S LN++L++ W S+V+ + PS +A I+TF + G F FEEC +RIAQP + + YF+ G + E Y + +V ++ Y++ ++ GM++RI SA+IYRKAL LS AS+G+S++GQMVNLL+NDV+RFD++ +F+ YLW P+Q I V+ +T G +AG ++I + Q+++G++FS+LRL TA KTD+RI+IM+EI++GIKVIKMYAWE PF ++V + R + +LL + + VL INA+K+FL L++ ++L +T F P I+ SEALVS+KRI++FLL+ E RD S H P P++V + ++ W + E TLKN+ + G++ AI+GPVG GK++I+Q+LLGE P GEINI+GR+SYA+QE W+FSGSVR NIL G+ ++K+Y + + V ALEHD+ +W GD T VGE+G++LSGGQK+R++LAR +Y ADIY+LDDPLSAVD VG+ L++ CIQ L K VILVTHQ+Q+LK+A+ I++L G IE GTY +L+S + F ++ +EE+D + D+ L+D+ + + + R + +R R S SL++ + G S ++ P+E G + E+ GSVSL Y YF +G L V L+L T LF D WL +WTN +++ E Q T +A + I S +LII + L + L F+ C SS LH MF+K+ SRFFD+NP GR+LNRFSKD+GS DELLPP L LS GI +I P++ ++ ++ + +RKYYL++SRA+KR EGI +SP+FSQLASSL GLT+IR+ K E +LI EFD +QDIHTS++YSFL R+F D ++ L+ V F+F ++ + GDVG+ LT + L GM+QWG+RQ+AE+EN MTS ERV EYG + E LK D D SWP +GVIE NV L+Y +VLKG LTEP G+I +DGVNI + L ++R +ISIIPQDPL+F G++RKNLDPF+EY + IW AL++A L A+ + G+ETE+SEGG+N S GQRQL CLARAILR NK+LI+DEATANVDP TD IQE IR F DCTV TIAHRL+TVMDSDRILVMSDG + E +P DLL D ++ ++V+ +G S L++IA+
Sbjct: 343 AIIFIKWTIPFIRKGQKEDFDVHDLYKTLREDYSRELNDRLEKEWQKELSKVKTFSGNYHPSFAKAAIRTFRLQTLLSGXFVLFEECVLRIAQPFAIFKIIGYFSSGGTXMSEXELYFWSGILVGAGVIFVLFDQRYWYLSLKTGMQLRIAASAIIYRKALTLSKASLGRSSIGQMVNLLSNDVNRFDNSTVFLQYLWVAPIQFICVMLITSYFAGIEAVAGGALLIFFIFFQTYMGKMFSKLRLMTASKTDIRIQIMNEILDGIKVIKMYAWETPFVQLVTNAR------------------------NRFVLLPVFLLMVLFGVEINAQKIFLIFGLFDAIKLPLTHFFPSAISASSEALVSMKRIEEFLLLNELRDVQSKIN--HVILPGRYEPLTVEVTKISGKW-LDSSNEFTLKNISFSVEIGELCAIIGPVGCGKSTIIQSLLGEFPVSYGEINIKGRISYASQEAWIFSGSVRQNILMGKPLIDKRYREVIRVCALEHDVREWPDGDYTFVGEKGISLSGGQKSRINLARCVYASADIYILDDPLSAVDPHVGQQLFDTCIQKFLSDKTVILVTHQLQFLKNANNIILLNSDGEIEASGTYEKLMSQ-SGFVTYLEATSEEEDSDLLSDV--LSDVKSDGEYM---RSQKKKLKKGVRSRRSST------SLLVPVPYIGGSTER--DTFPEEKG-SQEWKMGSKETIIEGSVSLSLYHKYFVAGGGFFKFLCVYFLSLITHTLFVVSDWWLRLWTNAADARKLGPLPPTFYFSEYQDMTLQITADFQVDFFNFIYCSIYLSLIIILLFSAQLSVRQL------FMSCMRSSQTLHDRMFEKVAFTNSRFFDLNPNGRILNRFSKDIGSXDELLPPAL-------LSGSGIFILISMTNPLIVVGIVVLLLILLTIRKYYLNASRAVKRLEGITRSPVFSQLASSLDGLTTIRSMKIEEMLIEEFDYLQDIHTSSYYSFLVVNRFFAFCGDLMLSLFTASMVSMFLF----------YNRDATGGDVGLSLTLSLALCGMIQWGLRQSAEVENFMTSVERVAEYGDLPKEKGLKGDIKLD----PSWPDKGVIEFSNVNLKYDGTTPYVLKG------------------------------LTEPEGKIFIDGVNICRLSLQDVRKKISIIPQDPLLFKGTIRKNLDPFDEYGELAIWHALEQAKLSVAVSELEGGLETEVSEGGNNFSVGQRQLFCLARAILRKNKVLIMDEATANVDPMTDSLIQEAIRTEFKDCTVFTIAHRLYTVMDSDRILVMSDGEIKELGAPLDLLSDPSNIFYQMVNQLGPSAAERLKKIAQ 1592 HSP 2 Score: 310.842 bits (795), Expect = 1.241e-86 Identity = 155/301 (51.50%), Postives = 206/301 (68.44%), Query Frame = 0
Query: 1053 MLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIA 1353
M+QWG+RQ+AE+EN MTS ERV+EYG++ E L+ D D SWP +GV+E NV ++Y + + +VLKG++F T S EKIGI+GRTGAGKSS+I ALFRL EP GEI +DG++I ++GL ++R +ISIIPQDP++F+GS+RKNLDPFNE+ D QIW AL++A L + + G+++ + E GSN S GQRQL CLA AILR NK+LI+DEATANVDP TD IQE IRK F DCT EF +P DLL+D +++LS +V+ +T LR +A
Sbjct: 1 MIQWGLRQSAEVENFMTSVERVVEYGELPKEKGLESDIKLD----PSWPDKGVVEFSNVSMRYSQHQPNVLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEPEGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCT--------------------------EFGTPKDLLKDPNNLLSRMVAQSEPNTAHTLRHLA 271 HSP 3 Score: 64.3142 bits (155), Expect = 2.260e-10 Identity = 54/213 (25.35%), Postives = 99/213 (46.48%), Query Frame = 0
Query: 373 AMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALL------GEIPTDQ------GEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVD 573
A V + S++R+ ++ + + S ++ D S P + + S + + + LK L + + + + I+G G+GK+SI+ AL GEI D G ++I+ ++S Q+P +F+GS+R N+ F + + LE + L + G ++V E G S GQ+ LA AI R + ++D+ + VD
Sbjct: 10 AEVENFMTSVERVVEYGELPKEKGLESDIKL-DPSWPDKGVVEFS----NVSMRYSQHQPNVLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEPEGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVD 217
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000000741 (supercontig:LSalAtl2s:LSalAtl2s111:116041:261433:1 gene:EMLSAG00000000741 transcript:EMLSAT00000000741 description:"maker-LSalAtl2s111-snap-gene-2.14") HSP 1 Score: 795.808 bits (2054), Expect = 0.000e+0 Identity = 421/939 (44.83%), Postives = 594/939 (63.26%), Query Frame = 0
Query: 1 MDADDVIIQRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVE-----DETRKSE--PSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLK-KGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPT-CIMAVLFVMLR 930
MD ++ + ++N R NA+ LS FF W+ PLLR G K ++ DL L D S L++ L+R W ++E D T K PSLLRA+I+TFG G G F+F EEC R+ QPL +S V YF+ + + + Y++ +++ LY F+HH YFFGV++VGMR+RI SAL+Y+K+L+LS AS+GKS+VGQMVNLL+NDV+R+D LFIHYLW PLQ ILV +TW VG S++ G I++ +PLQ+WIG+ FSRLR+ A KTD RIR+M+EII G+KVIKMYAWE PF +VV +TR E+ I++T ++ FN FFFTS++V+LL I ++ N+VI+++ +FL L+NTVRLS+TLF P I+M SEALVS RIQ+FLL+ E S + E P E + + +K ++ W + + L+N+ Q ++ AI+GPVGSGK++ILQALLGE P G+I+I G++SYA+QEPW+FSG++R NIL G + K+YLK L+V +LEHD+ W D T VGE+GVALSGGQKAR++LAR++Y +AD+YLLDDPLSAVD+ VG++LYE+CI+ +L K VILVTHQIQYL DA I++L KG IE +GT +LL S DF+ F+ EE D + D L + + S ++ + +R R SV S + + + + E+++ P E + + TES GS+S+ Y YF +G + V LN+ +Q LF D WL WTN +A+ N +++S E +I+ N I+ + AL+I S + F ++C SS NLH +MF+K+I FFD+NPVGR+LNRFSKD+GS+D LLP L+D IFL+ +G+ G+I+ +P V P I +F +LR
Sbjct: 1 MDIEEKVNLKDNKRSNANILSKIFFIWVLPLLRDGQNKAFDIPDLPSALTEDKSRYLSDNLEREWKKELEKGLRYDNTSKKRYSPSLLRALIRTFGSSLGVYGAFSFIEECVFRLLQPLAISQIVLYFSNSNHGISPTQLYIWSAVLIMSGVLYVFSHHWYFFGVVQVGMRIRIACSALLYKKSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFIHYLWVAPLQFILVSIITWYMVGISSMCGGAILLVFIPLQTWIGKQFSRLRILIAGKTDKRIRVMNEIIEGMKVIKMYAWEYPFMEVVNETRRDEIQTIKKTYEYKAFNLGFFFTSSRVVLLLIFFLMIIGNEVISSKNIFLIFGLFNTVRLSLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRP-EVSLRIEMKNVSGKWTSNEKDDD-LRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECIKNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLLMSERDFTSFLVAQEEETDS------------IFDEDELALTPKKSLNIENYMRRRQSSVSS------IGSRATIDTNAMEYNDI-PNEGRRTQT-----TESKVKGSISVALYKKYFYAGGGKWIFFFVYGLNILSQLLFVSTDWWLKQWTNAA-----DARTNNYANASSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISIRKFLILCLKSSKNLHLEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGSLDXLLPLALSDTSLIFLNAVGMFGLIISTEPKVLIPLGLIQRWVFPLLR 908 HSP 2 Score: 580.096 bits (1494), Expect = 5.261e-179 Identity = 327/791 (41.34%), Postives = 484/791 (61.19%), Query Frame = 0
Query: 362 LSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLK-KGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTN-----------QEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQY-GEGEKHVLKGVDFVTKSKEKIGIV 1139
+S+TLF P I+M SEALVS RIQ+FLL+ E S + E P E+ + + +K ++ W + + L+N+ Q ++ AI+GPVGSGK++ILQALLGE P G+I+I G++SYA+QEPW+FSG++R NIL G K+YLK L+V +L+HD+ W D T VGE+GVALSGGQKAR++LAR++Y + D+YLLDDPLSAVD+ VG+YLYE+CI+ +L K VILVTHQIQYL++A+ I++L KG E +GT +LL S DF F+ EE D H N+L PR+ S ++ + +R R SV S + + + ++ E+++ P E + + TES GS+S+ Y YF + + V LN+++Q +F D W WTN + + + + ANT+ S E +I+ N I+ + AL+I S + F +C SS NLH +MF+K+I FFD+NPVGR+LNRFSKD+G++D+LLP L+D IFL+ +G+ G+I+ +P + P + ++ + LRKYYL++SR++KR EGI KSP+ SQL+++L G+++IRA K E+ SEF +QDIHT+A++SF + TR+FG W+D +V + + V F+F F+V + GD+G+ L+ +++ +QWG+RQ+AE+EN MTS ERV EYG + SE L D D SWP +GVI+ NV+L+Y +G ++LKG+ F S EKI ++
Sbjct: 1148 ISLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEES-LRIEMKNVSGKWTSNEKDDD-LRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECIKKYLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLLMSERDFKPFLVAQEEETDSIF-----HKNELA------LTPRK-SLNIENYMRRRQSSVSS------IGSRATIDTNVMEYNDI-PNEGRRTQT-----TESKVKGSISVALYKKYFYADGGKWMFFFVYGLNISSQLIFVMTDWWXKQWTNAADARKKFGDIRNQKHFFSSYANTS----SFEILPGFQIDLFNSIYYGIYFALVGALIICSQISVRKFIFLCLKSSRNLHSEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGALDDLLPIALSDTNLIFLNAVGMSGLIISTEPKILIPLLAILIILLALRKYYLNASRSVKRLEGITKSPVISQLSTTLNGISTIRASKLENNFASEFHYLQDIHTAAFFSFQSVTRFFGFWVDGIVSINVXATVVIFVF----------FNV--KGGDIGISLSLSVLMARXIQWGLRQSAEVENYMTSVERVAEYGDLPSEKRLTSDKKID----PSWPNKGVIKFHNVKLKYDDQGGPYILKGLTFTINSFEKITLI 1892 HSP 3 Score: 226.483 bits (576), Expect = 5.901e-60 Identity = 116/265 (43.77%), Postives = 160/265 (60.38%), Query Frame = 0
Query: 27 WLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVE-----DETRKSE--PSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKV 284
W+ PLLR G K + DL PL D S L++ L+R W ++E D T K PSLLRA+I+TFG G G F F E C RI QP+ +S V YF+ + + + Y++ +++ LY F+HH +FFG++ ++L+LS AS+GKS+VGQMVNLL+NDV+R+D LF+HYLW PLQ ILV + W VG S++ G I++ +PLQ WIG+ SRLR+ A KTD RIR+M+EII GI +
Sbjct: 902 WVFPLLRDGQNKEFDTPDLQSPLSEDKSRYLSDSLEREWKKELEKGLIYDNTSKKRYSPSLLRALIRTFGSSLGVYGPFVFMENCVFRILQPIAISQIVLYFSNSNHGISPTQLYIWSAVLIMSGVLYVFSHHWHFFGMV----------------QSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFLHYLWVAPLQFILVSMIAWYMVGISSMCGGAILLVFIPLQIWIGKQLSRLRILIAGKTDKRIRVMNEIIEGISL 1150 HSP 4 Score: 95.1301 bits (235), Expect = 9.452e-20 Identity = 110/460 (23.91%), Postives = 204/460 (44.35%), Query Frame = 0
Query: 888 PPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPI---------FSQLASSLGGLTSIRAYKAE----------SILISEFDRIQDIHTSAWYSFLATTRWFGL-WLDWLVVLYLGFCVGTF--------IFMGDGSSHEAMFSVGSQSGDVGVV--LTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADL--KVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHV-LKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWI-QETIRKRFADCTVLTIAHRLHTVMDSDRILVMS 1313
P +L +I F S LG+ G VF + VF +A+ ++L Y+ +S+ I ++ S + FS G + S++ KA ++L ++ +R Y ++A ++ + + W +V C G I++G S + G + V+ + I LT + T+E + ST+R+ + +E D+ + H P++ +PE R IE +NV ++ EK L+ V F +E I+G G+GKS+++ AL GE V +I G +IS Q+P +F G++R+N+ + + LK LD + S P T + E G LS GQ+ + LAR++ + +LD+ + VD ++ +E I+K + TV+ + H++ + +++ I++++
Sbjct: 960 PSLLRALIRTFGSSLGVYGPFVFMENCVFRILQPIAISQIVL--YFSNSNHGISPTQLYIWSAVLIMSGVLYVFSHHWHFFGMVQSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFLHYLWVAPLQFILVSMIAWYMVGISSMCGGAILLVFIPLQIWIGKQLSRLRILIAGKTDKRIRVMNEIIEGISLTLFFPNTISMTSEA---LVSTDRIQNFLLLEEIGDICSSMKHEPEV-RPEESLR---IEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALL------GEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECIKKYLSRKTVILVTHQIQYLREANNIILLN 1398 HSP 5 Score: 88.9669 bits (219), Expect = 7.495e-18 Identity = 75/277 (27.08%), Postives = 132/277 (47.65%), Query Frame = 0
Query: 1068 MTSTERVLEYGKIESEADL--KVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHV-LKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWI-QETIRKRFADCTVLTIAHRLHTVMD-SDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVS 1339
+ ST+R+ + +E D+ + H P++ +PE R IE +NV ++ EK L+ V F +E I+G G+GKS+++ AL GE V +I G +IS Q+P +F G++R+N+ + + LK L+ + S P T + E G LS GQ+ + LAR++ + +LD+ + VD + +E I+ + TV+ + H++ + D S+ IL+ + G + + + LL S LV+
Sbjct: 386 LVSTDRIQNFLLLEEIGDICSSMKHEPEV-RPEVSLR---IEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALL------GEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECIKNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLLMSERDFTSFLVA 646
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000002221 (supercontig:LSalAtl2s:LSalAtl2s1420:21426:31801:1 gene:EMLSAG00000002221 transcript:EMLSAT00000002221 description:"maker-LSalAtl2s1420-augustus-gene-0.12") HSP 1 Score: 757.288 bits (1954), Expect = 0.000e+0 Identity = 472/1389 (33.98%), Postives = 759/1389 (54.64%), Query Frame = 0
Query: 4 DDVIIQRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEV--------LNNKLQR-----------HWDSQVEDETR---KSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVIL-LAILIPFVLSN--QVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH---LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEH-----TEEDDDAIAGDLEH---LNDLMAP-SDTLCVPRRFSAS------VTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANS-VPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINAS----NKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKV-DHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEP-TGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVG 1342
+D+ P +SF S F WL+ LL G+K+NL +DL+ + S L++ L+R D VE +T+ K + S+L A+ +TFG + + + PL L + F+ Q + + LY + + S + + +F+ + VGM+++ +L + IYRKALR+ +++ + G++VNL++ D + +I+ +W+ P Q+ + + L W+ +G S LAG ++I +P +I L+ K+ D RI++++E++ GIK++K+YAWE F ++ + R KE+ ++ Y + N SF +T ++ L F+LS+ V+++EK F+ L L+N +R +++ +P I + A VSIKRI F+ E D + + ++ + +++++ W+ + ++ L ++ L + G +VA+VG VGSGK+S+L A+LGE+ G I ++G ++Y AQ+ WV + S+++NILF +++ KY + +E AL+ D+ GD T +GE+G+ LSGGQK RVSLARA+Y +DIYLLDDPLSAVD+ VGK++Y+ I + LK K ++VTH + YL D I+V+K G + GTY ELL F+EFI + E ++ I D+E N+L+ + + R S S VTS +++ + S S SL S E ++D K+ S + E GSV Y Y ++ + LV+ A + Q L T +V L W+ +A + + ++ T++EIN L I+GG L I+ ++ + +L C +++ LH M + I+++P FFD P GR+LNR KD+ +D ++P VL IS FL +L + V++ P+ P ++ + + +++ Y+++SR +KR E ++SPI S + ++ G +IRAY S ISE + D + A + + RW + L+ +V + F +G S G VG+ ++ + +T L W +R +E+E + + ER+ EY K E EA + D PD E WPR+G I +N +Y EG +VLK V + EKIGIVGRTGAGKSS +++FR+ EP TG I++DGV+I ++GLH+LR +I+IIPQDP++F GSLR+NLDP +EY + I +A+ +HL I S+ G+E +SEGG NLS GQRQL+CLARA+LR ++LILDEATA VD TD IQ+TIR F D TV+TIAHRL+T+MD +ILV+ +G E+ + +LL D+ S + S+ G
Sbjct: 209 NDIKSNNPCPLITSSFPSQISFSWLDSLLWTGFKRNLSFDDLWDLVPSLSSRTVVPIFLQRLDSALRRVKTNENGITYAKGDDNVEVKTKHEKKPQLSILPALARTFGPSILSAAVIKIVSD-SLNFVPPLILKRIIK-FSTNQEELWK--GILYAVILFASSTVGSLVLSKFFYKMYVVGMKIKTSLISTIYRKALRVPTSTKKNISTGEIVNLMSVDAQKIVDLMPYINTVWSAPFQITIAIYLLWQTLGPSVLAGVLVMILLIPFNGFIASRTKTLQTNQMKEKDERIKLLNEVVQGIKIVKLYAWEQSFLDIISNVRSKEVKILTHIGYLQAGN-SFIWTCAPFLVSLVTFATFILSSPENVLDSEKAFVCLTLFNILRFPLSM-LPMIIGSMVLAGVSIKRINKFMNSEEIDEEA----VEKKTAYPDDKFAINLEKACLKWESD-EDKNILSDVSLDIEVGSLVAVVGTVGSGKSSLLSAILGEMDKVSGLITVRGSIAYGAQQAWVLNTSLKNNILFNKSYDGDKYTRIVEACALKSDLDMLPGGDETEIGEKGINLSGGQKQRVSLARAVYSGSDIYLLDDPLSAVDSHVGKHIYDNVISSSSGILKDKTRVMVTHGVTYLPFTDKIIVMKDGRVSEIGTYKELLRQKGAFAEFIVQFLSEANENEVNENIKHDIEESFGKNELLEQITKAKQIVRERSVSLNSGDLVTSLVKNNPTNSASGSTTSL------KENSGDESTDNDTKQTRPTTSQTQQYQDEKVETGSVKWNIYMHYVKNMSIILVV-ACSSCFVIYQALNTLSNVLLAWWS--------DAVMKIEVRTGLNDNRTLDEINQDIMDXQVYYLSIYGGYCLGQGIVVVMGFVFMYLACMEAAQRLHNQMLESILKSPMSFFDTTPQGRILNRLGKDLDVLDSVMPMVLRGWISCFLGVLSSLIVVMVTTPVFIIPASLIIICYFFIQRIYVATSRQLKRLESSSRSPIXSFFSETVSGAATIRAYGQSSTFISESESKVDDNQKANFPATVSNRWLAVRLE-VVGNLIVFTAALLAVLGRDSL---------SPGLVGLSVSYALAVTASLNWLVRMASEVETNIVAVERIQEYTKAEKEAPWIIEDTKPD----EDWPRKGEISFKNYSTRYREGLDYVLKNVSLDIEGGEKIGIVGRTGAGKSSFTLSMFRIIEPVTGNIIIDGVDITKLGLHQLRSRITIIPQDPVLFSGSLRRNLDPLDEYNETNIMEAISHSHLKPFIDSLKDGLEYHVSEGGENLSLGQRQLICLARALLRRTRVLILDEATAAVDLETDNLIQKTIRSEFKDSTVITIAHRLNTIMDYSKILVLKNGERVEYGTVAELLADKKSQFYSMCSDAG 1557
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000011700 (supercontig:LSalAtl2s:LSalAtl2s812:79332:86643:-1 gene:EMLSAG00000011700 transcript:EMLSAT00000011700 description:"maker-LSalAtl2s812-augustus-gene-0.6") HSP 1 Score: 711.449 bits (1835), Expect = 0.000e+0 Identity = 442/1352 (32.69%), Postives = 725/1352 (53.62%), Query Frame = 0
Query: 12 NPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWD-----SQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLM--SALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLS---NQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGE-RDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIP-TDQG--EINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH--LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQS----GDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTE-PTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVG 1342
+P + S FF W++ L+ G+K+ ++ DL+ + + ++N +HW+ ++ + PS+ A+++++ G F + I P+ L + + + +G+ A L V+L L TF YFF ++ VGM+++ ++++LIYRKALR+ S + +T G++VNL++ DV + ++ +W+GPLQ+I + L +G+S LAG ++ +P+ +I +++ KK D R++ M+EI+ GIK+IK+YAWE F+K++ R +E+ +++ ++ + GF ++T I L I +V+S N ++++EK+F++++L+N +R + + + I ++ A VS+KRI FL E + HD P S + ES K++ + G ++AI+GPVGSGK+S++ ALLGE+ T +G + I G ++Y Q W+ + SV+ NILFG F + Y + L+ +LE D+ + GD T +GE+G+ LSGGQK R+SLARA+Y +DIY LDDPL+ VD+ V K+L+E+ I ++ L+ K ILVTH + +L D I LK G I +GTY EL+ DFSE I H N + SD+ V + + T + ++ + +DE E+ G V + YW YF S L + + +Q L T VWL +W+ +A+ NT + +L I+ G+ ++ + +S T+ L D+S LH +F+ II+ P FFD P+GR+LNRF +D+ +D + + ++ + + V +I PI PT + V++ ++ LSSSR +KR +A SPI+S +L G+ ++RAY E SEF+R D + + + RW G+ ++ +G FI A+FSV S+ G +G+ ++S + +T +L W +R +++EN + + ER+ EY ESEA +++ D+ SWP +G I +N+ L+Y + VL+ ++ +KIGIVGRTG+GKS+L +ALFRL E +G+I +DGV+I+++GLH LR +++IIPQDP +F G+LR NLDPF ++D ++ ++LK A+L ++ G++ ++E G N+S GQRQL+CLARA+LR NK+LI+DEATA VD TD IQ+ I+ F D TVLTIAHRL TV+D +I+V+ G + E+ SP +LL D S ++ N G
Sbjct: 745 SPDTQCGYPSYIFFSWMSSLMWKGFKRPIKQKDLWDFIPSVNTALVNPHFLKHWNKIYTQTKFSNYPTSKSPSIFPALLRSYW-PLLLKGAFAKLLHDLLLICSPMLLQYLILFSYSPDIPLGQGIA----LSVILFGNKILGTFFIARYFFYMVTVGMKLKTSITSLIYRKALRIHS-TRDDTTSGEIVNLMSVDVQKIVDLMPLLNTIWSGPLQIIAAIYLLINTLGYSALAGVLVMFLLIPINGFIAVRMKNAQMKQMKKKDERVKKMNEILQGIKIIKLYAWESSFSKLISSIRFEEIKLLKLSSKYFGFMMLTISSTTFFISLFTFIVYVVSDPENHILDSEKIFVSISLFNILRFPLNMLT-HVIGGIASASVSLKRINKFLASEELEEGILVRSNSHDHQAICIHPSSSFSW--------KGSSESLFKDISMDVNRGNLIAIIGPVGSGKSSLISALLGEMLFTSKGTNPVEIHGSVAYTPQNAWMQNVSVKDNILFGRKFNKNWYDEVLKACSLESDMEXFPSGDSTEIGEKGINLSGGQKQRISLARAVYSQSDIYFLDDPLAXVDSHVAKHLFEEVIGSNGLLRGKTRILVTHNLSFLHLVDEIYFLKDGEITEKGTYKELMEKNCDFSELISNHAN-------------NKITNQSDSEKVMEKINEEGTKQPIETNFKI---------------------YDE-----------------ETLHTGQVGIRVYW-YFLSKIGMLAGILAFSFFIISQILATGSSVWLSVWS--------DAKNNTDIY-----------------YHLGIYAGLGVSNIFISTAGTLILSLSLLDASRILHGTLFQCIIKTPMSFFDTTPLGRILNRFGQDIEVLDTKMSFCIFGSMTGTFAYIATVTIISINVPIFIIPTLAIFVVYFVILIVSLSSSRQLKRLSSVATSPIYSHFGETLSGINTVRAYSLEKAFYSEFERRLDEYQKRNFPVIMADRWLGIRIN---------LIGNFIIFA-----SALFSVLSRDTITPGQLGLNVSSSLAITSILSWVIRMYSDLENNIVAVERIKEYSNKESEAPWELEE--DLKLNSSWPLKGEITIKNLSLKYRKDLDWVLRDINVHISPGDKIGIVGRTGSGKSTLALALFRLLEVNSGQITIDGVDIKKMGLHTLRSKLTIIPQDPTLFSGTLRLNLDPFGLFKDMELIESLKHAYLQDFLKE--DGLDKVIAENGENISLGQRQLICLARALLRKNKVLIMDEATAAVDSETDKLIQKAIKDNFRDSTVLTIAHRLQTVLDYSKIIVIDSGCIIEYDSPKNLLSDSSSTFYKMCLNSG 1986
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000008248 (supercontig:LSalAtl2s:LSalAtl2s498:229862:245360:1 gene:EMLSAG00000008248 transcript:EMLSAT00000008248 description:"maker-LSalAtl2s498-snap-gene-2.25") HSP 1 Score: 701.819 bits (1810), Expect = 0.000e+0 Identity = 444/1360 (32.65%), Postives = 734/1360 (53.97%), Query Frame = 0
Query: 17 ASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETR----KSEP-SLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTK-VILLAILIPFVLSNQ--VINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEAL---VSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH---LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSS-GTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLC-----VPRRF-------SASVTSEIRHRSY--SVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRN--LIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQS----GDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSN 1340
ASF S F W +P + +KK + +DL+ E + + WD ++E E R K++P ++L ++++F FF + P + +++ + + + + YL+ + + ++ Y+ + G+++R +L++ I+ KA+ L S+S + +VG+ NL+A D R CL+I +W+ PL++I+ + L W+ +G ++LAG ++I +P+ +G+ + + D RI++M +I+NGIKV+K+YAWE F V + R +E+ ++++A SF +TS ++ LA +VL ++ ++ F++L T+ + L + M+ +A+ VS+ RI FL + D + I ES + +V + ++ +W+ +G +TL+++ L + G +VAIVG VGSGK+S+L +LGE+ +G IN+ G+ YA Q+PW+ + ++R+NILFG+ F +K Y + ++ AL D+ GD T +GERG+ LSGGQKARVSLAR + DIY+LDDPLSAVD VG++L+E I + LK K I VTH +L D I+V+K G I GTY +L+ +F++F+ + ++ + I + + L ++ ++ + +R S ++T I+ Y S+ S+ ED + DE +L + I E G + L Y +YF+ +L + QG ++WL W+ + IN+++ RN L I+ + I +++ ++ + ++S+ +H + + ++RAP FFD NP+GR+LNRFSKD+ LP + +I+ ++LG + +I P F + + +++K+Y+S +R +KR E I++SPI+S A +L G+ +IRA+ I E D + ++ + ++RW + L+ LG + F+ A+FS+ S+ G VG+ L+ + +T +L + + ++E M S ER+ EY I EA + P+ P +WP GVI+ N + +Y +G VLKG++ + EKIGIVGRTGAGKSSL +ALFR+ EP+ G I +DG NI+ +GL +LR +I+IIPQDP++F GSLR NLDPF + D IW AL+ +HL + ++ G+ + EGG NLS GQRQL+CLARAILR +IL+LDEATA +D TD IQ TIR F D TVLTIAHR++T+MDS+RI+V+ G +AEF P +LL + S+ LV++
Sbjct: 226 ASFTSKLTFSWFDPFIYKAWKKXVTDDDLYEI----NDEFKSCGVLPSWDREMEKEIRRKHLKNKPINILWPLVRSFKSTLLASSALQFFYSV-FQFGAPQLVDLIINFVSDPKEPIWKGYLYLFAICSITFINTLIYSQSNYYSYI--TGLKIRTSLTSSIFNKAVNLKSSSKKQMSVGETTNLMAIDSQRLMDFCLYIDMIWSSPLKIIIAMYLLWQVLGPASLAGLAVMILLIPINIVVGKKVKKFTAIQMQNKDKRIKLMDDILNGIKVLKLYAWEPSFIDAVTNFRVQEIGALKKSALINAVT-SFMWTSAPFLVALASFTTYVLIDEKNILTPSTAFVSL----TLFNLLRLPLNLLPMMIMKAIQSKVSLDRINLFLNKEDLDLLA----ISHES---QGSHAVKMCNVSLSWETD-EGLNTLEDIDLDIEKGSLVAIVGQVGSGKSSLLSGILGEMEIVRGSINVDGQTIYAPQQPWLQNETLRNNILFGKRFNKKLYRRVIDACALSPDLDMLPAGDLTEIGERGINLSGGQKARVSLARCTXNNGDIYILDDPLSAVDVHVGRHLFENVISSQTGLLKNKTRIFVTHGAIFLPQTDKIIVMKNGVISESGTYRDLIEKENGEFAQFLINYLVDEKENILKNDQDLKTIIKDLESTVGGSEELEKRLEAAQSDKSTALTDLIQGTKYLDENTSDQCSSIASRKGED-----DLDEVVSNDLNER----LIEEEKIESGGIKLNIYLNYFKRTGLLASFFGILFY-FSYQGFSLGANLWLSKWSTDRAA-----------------------INSTSIRNHYLEIYAILGFFQSIFTMLGSVTIAIGTLNASMKIHGKLLENVLRAPLSFFDTNPLGRILNRFSKDIDVAXTTLPFNIRMMIAQSFNVLGTIVIICIALPWFFVIILPAVICYALIQKFYISCARQVKRIESISRSPIYSHFAETLTGIPTIRAFGMVHHFIDENVNKIDFNAKCYFPTVISSRWLAVRLE-----TLGNILVIFV---------ALFSITSRGTTDPGMVGLSLSYALSVTTILNMLITVSTDVETNMVSVERIKEYENIPQEAPYDL---PNSDPPPNWPEHGVIKFDNYKTRYRKGLDLVLKGINCTIQKGEKIGIVGRTGAGKSSLTLALFRIIEPSEGSIYIDGENIRFLGLGKLRSRITIIPQDPILFSGSLRMNLDPFEAFADRDIWIALEYSHLKSFVWNLGDGLNFSVLEGGRNLSVGQRQLICLARAILRKTQILVLDEATAAIDLETDDLIQSTIRSEFKDSTVLTIAHRINTIMDSNRIMVLDAGTIAEFDDPQNLLANPDSMFYSLVND 1515
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000003611 (supercontig:LSalAtl2s:LSalAtl2s197:49356:53594:-1 gene:EMLSAG00000003611 transcript:EMLSAT00000003611 description:"augustus_masked-LSalAtl2s197-processed-gene-0.4") HSP 1 Score: 395.586 bits (1015), Expect = 9.361e-116 Identity = 233/625 (37.28%), Postives = 344/625 (55.04%), Query Frame = 0
Query: 726 IHTESAALGSVSLGTYWSYFRSGAHSLVLLA--VLILNLATQGLFTF-IDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQS----GDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEP-TGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVG 1342
I E G VS WS ++ S+ L ++I N LF F +WL WT ++ N T+ D L ++G + + + + ++ + +S +H + +I+RAP FFD P GR+LNRFSKD+ D +L + + LGIV +IV P+ +++F++++ Y++SSR +KR + + +SPI+S + SL GL+SIRAY A+S I E D + Y + RW + L+ +G G A+ ++ + G VG+V++ ++LT L W RQT+E+E + + ER+ EY ++ E + ++ H D +WP +G +E +N L+Y VLK ++F E++GIVGRTGAGKSSL VALFR+ E G+IL+DG +I +GLH+LR +++IPQ+PL+F G+LR NLDP N + D IW L HL + IR + G+ +SEGG NLS+GQRQL+CLARA+LR+ KILILDEATA VD TD IQETIR F CT+LTIAHRL T++D D+ILV+ G V EF SP +L + SV +++ G
Sbjct: 814 IQKEGLETGRVS----WSVYKYYIQSIGFLGAFLIIFNQMLNQLFGFGSSIWLEAWTQED-------YGNATIPKYRD-------------LYLGVYGALGIGQAVTIFLLSLSVAMFTLKASKVIHNQTYDRIMRAPISFFDSTPQGRILNRFSKDISICDNILGSNIRQWLXCLFXFLGIVILIVSVLPLFLLFALPTSLVFILIQNIYVASSRQLKRLQSVTRSPIYSHFSESLNGLSSIRAYGAQSKFILESINKIDTNQRCNYPSIIANRWLAMRLE---------TIGNLCIFG-----XAILTMTNPELVGPGKVGLVISYALILTQNLNWLXRQTSEIETNIVAVERLKEYAGLDIEKEWRL--HKD--TSYNWPSQGKVEFKNYSLRYKANSDLVLKKINFTIFGGERVGIVGRTGAGKSSLSVALFRIVEAANGQILIDGKDISTLGLHDLRESLTVIPQEPLLFSGTLRSNLDPENAFSDHDIWNTLGSVHLKEYIRDLKDGLNHSISEGGLNLSSGQRQLMCLARALLRSCKILILDEATAAVDWETDEKIQETIRCYFPSCTILTIAHRLKTIIDYDKILVLDKGTVIEFGSPNELYMNSDSVFHSMINAAG 1396 HSP 2 Score: 367.466 bits (942), Expect = 5.896e-106 Identity = 212/632 (33.54%), Postives = 359/632 (56.80%), Query Frame = 0
Query: 9 QRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDET--RKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSY----FAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVIL-LAILIPFVLSN--QVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH---LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELL 628
+ENP+++ASF S+ F+ W+ PLL G+KK + +DL+ LN L S+ D+ + + ++K FG EF FF + + + P + +++ F + S + YLY ++++S L + YF V V MR+R +L++L+YRK L+LS++S +VG++VN+++ DVSR F+ LW+ P Q+++ V + E+GW+ + G GI++ ++P+ + + + +++ K D R +I++E++ GI+++K+YAWE + ++ R E+ ++++ A+ F F ++ST I+ LA FV+ + ++ AEK F+T + N +++ M F P+ I A VS+KRI L E + + ++ ++ I+ W + E+TL N+ L+ K G + AIVG VGSGK+S++ A+LGE+ G++ I+G+++Y QE W+ + S+++NILFG+ + E+ Y + LE L +D+ GD T +GERG+ LSGGQ+ R+SLARAIY DAD+Y+ D+PLSA+D+QVGK ++ + + +K K +LVTH I YL I V+ KG I GTY ELL
Sbjct: 152 NKENPKKDASFFSLLFYEWITPLLWKGFKKPITEDDLWN---------LNKDLTCGETSRRLDQYYFKSGNKKIGIPLMKAFGFEFVIGSTIKFFSDI-LSMVLPQIMKLMINHADSEFEMKERSW---KGYLYPSMLIIVSFLQSVLLAKYFEIVFLVSMRIRASLTSLVYRKCLKLSNSSRKNKSVGEIVNIMSVDVSRIADLMPFLTLLWSSPFQIVVSVIFMYNELGWAIIGGTGILLITIPVNAILSYFGKKFQMKQMKAKDNRTKILNEVLGGIRILKLYAWEPSYINKIEGIRGVEIGILKKAAWLTSF-MGFIWSSTPFIVALASFATFVMVDDRNILTAEKAFVTQSYINKMKMPMAXF-PFVIVXAISATVSLKRINQLLTSDELQKDAVERVPMKINQKIDQGDAIVIRDGNFKWSTE-DSENTLSNINLRIKHGSLTAIVGTVGSGKSSLISAILGEMVKKSGKVRIKGQIAYVPQESWMQNTSLKNNILFGKPYDEEWYNQVLEYCCLTYDLSLLPAGDETEIGERGINLSGGQRQRISLARAIYSDADVYIFDNPLSALDSQVGKSVFNNVLNNNTGIIKDKTRLLVTHGISYLPHVHHIAVMLKGEIIHEGTYQELL 767 HSP 3 Score: 92.4337 bits (228), Expect = 6.976e-19 Identity = 66/226 (29.20%), Postives = 112/226 (49.56%), Query Frame = 0
Query: 427 HQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGR-------------LSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTEL-LSSGTDFSEFI 638
++A + LK + G+ V IVG G+GK+S+ AL + G+I I G+ L+ QEP +FSG++R N+ F + TL L+ I + G + E G+ LS GQ+ + LARA+ R I +LD+ +AVD + + + E I+ + ++ + H+++ + D D I+VL KG++ G+ EL ++S + F I
Sbjct: 1168 YKANSDLVLKKINFTIFGGERVGIVGRTGAGKSSLSVALFRIVEAANGQILIDGKDISTLGLHDLRESLTVIPQEPLLFSGTLRSNLDPENAFSDHDIWNTLGSVHLKEYIRDLKDGLNHSISEGGLNLSSGQRQLMCLARALLRSCKILILDEATAAVDWETDEKIQE-TIRCYFPSCTILTIAHRLKTIIDYDKILVLDKGTVIEFGSPNELYMNSDSVFHSMI 1392 HSP 4 Score: 83.9593 bits (206), Expect = 2.667e-16 Identity = 117/534 (21.91%), Postives = 220/534 (41.20%), Query Frame = 0
Query: 826 LVIMSLVRTI----HF---FLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLP--------PVLTDVISIFL------SILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFG-LWLDWLVVLYLGFCVGTFIFMGDGS--SHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYG-EGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKR----FADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDR 1330
L+I+S ++++ +F FL+ +L +++K ++ + VG ++N S D+ I +L+P P V IF+ +I+G G+++ P+ A+L +K+ + +A I L LGG+ ++ Y E I++ + I+ + T + G +W ++ L TF+ + D + + E F S + + + + + L+TS E L+ +E +K++ D + I R+ ++ E ++ L ++ K IVG G+GKSSLI A+ GE+ +++ G ++ QI+ +PQ+ + + SL+ N+ Y + Q L+ L + +P G ETE+ E G NLS GQRQ + LARAI + + I D + +D + + + D T L + H + + I VM G + + +LL+ +
Sbjct: 276 LIIVSFLQSVLLAKYFEIVFLVSMRIRASLTSLVYRKCLKLSNSSRKNKSVGEIVNIMSVDVSRIADLMPFLTLLWSSPFQIVVSVIFMYNELGWAIIGGTGILLITIPV-------NAILSYFGKKFQMKQMKAKDNRTKI--------LNEVLGGIRILKLYAWEPSYINKIEGIRGVEIGILKKAAWLTSFMGFIWSSTPFIVALA-SFATFVMVDDRNILTAEKAFVTQSYINKMKMPMAXFPFVIVXAISATVSLKRINQLLTSDE--LQKDAVE-RVPMKINQKID--------QGDAIVIRDGNFKWSTEDSENTLSNINLRIKHGSLTAIVGTVGSGKSSLISAIL------GEM------VKKSGKVRIKGQIAYVPQESWMQNTSLKNNILFGKPYDEEWYNQVLEYCCLTYDLSLLPAGDETEIGERGINLSGGQRQRISLARAIYSDADVYIFDNPLSALDSQVGKSVFNNVLNNNTGIIKDKTRLLVTHGISYLPHVHHIAVMLKGEIIHEGTYQELLEKK 770
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000001655 (supercontig:LSalAtl2s:LSalAtl2s128:1836948:1854487:1 gene:EMLSAG00000001655 transcript:EMLSAT00000001655 description:"augustus_masked-LSalAtl2s128-processed-gene-18.4") HSP 1 Score: 328.176 bits (840), Expect = 1.585e-92 Identity = 200/625 (32.00%), Postives = 336/625 (53.76%), Query Frame = 0
Query: 721 NSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSV----GSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEY-GKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSM-PQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELV 1338
+SV + E+ + YW + +L+++ ++ +A+ D+WL W + + Q N T + + ++ G+ + I++L+R F ++ +H + ++RA FFD P GR+LNRFS D +ID+ LP +L +S + G V V V+ P + + + + ++ Y SR +KR ++ SPI+ ++ GL IRA KA + E + + + + A Y+ + + W + L +G+ + A+ SV +G VG+ ++ + +T L + E E + + ER +Y +I E+ V + P +WP +GV+E +++RL+Y + +VL V+F TK KEKIGIVGRTGAGKSSLI ALFRL+ + GEI+VDG+ I+ + L + R Q ++IPQDP +F G++R+NLDP+ ++ D ++W ++K ++L I S G++T + +GG +LS GQ+QL+CLARAI+ + K++ +DEATA+VD TD I+ ++ F D TV+TIAHR+ TV++SDRI VMS+G++ E P DL++ +S +L+
Sbjct: 872 DSVEEEMQETGVVAYRIYKKYWQAIGTYLAPTILISIFLMQVASNT----TDLWLSHWVSTDNFQ------NNTEDT---------------DHYIYVYSGLAVFHTILTLIRAFLFAYGGIHAAKIIHDLLLGVLLRAKIYFFDSTPAGRILNRFSSDTYAIDDSLPFILNIFLSQIFGVFGRVLVCVYAVPWILIVLLPLGLFYYEIQCKYRPGSRDLKRISSVSLSPIYEHFNETVHGLKIIRASKASQRFLLENEELVECNQKARYAAFSASLWLEIRLQ---------LIGSIVVFSI-----ALISVINFESVDAGLVGLAVSYALGMTXRLAEVVVSFTETEKELVAVERAYDYIDRIYEESYSGV-----LNMPYNWPNQGVVEFKDIRLRYKDHLPYVLNKVNFKTKPKEKIGIVGRTGAGKSSLIAALFRLSSFSHGEIMVDGIRIRLLPLIDFRRQFAVIPQDPFIFSGTIRQNLDPYAQHSDQELWDSIKLSYLYNIIYSFGSSGLDTLIGDGGKSLSIGQKQLLCLARAIITSAKVVFIDEATASVDKETDRLIRNVLKTAFNDKTVITIAHRIETVLNSDRIFVMSNGQIIEEGKPEDLIKSPNSEFRKLI 1452 HSP 2 Score: 300.442 bits (768), Expect = 1.659e-83 Identity = 196/633 (30.96%), Postives = 320/633 (50.55%), Query Frame = 0
Query: 14 RENASFLSIAFFWWLNPLLRLGYKKNLELN-DLFR-PLRVDGSEVLNNKLQRHWDSQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDE----SPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLS---YAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGT--DFS 635
+E+ S + FF W +PL+ G L + D+F P + V + D + +S +A+ F EF +GM F + PL L+ V + + + Y Y + + + L + + F + +G++VR ++ +Y++ L +S A++ K + G+++N ++ DV R + H W+ P Q+++ + L ++VG S+ G G I +P+ I L D R++I++EII GI+VIK Y WE FT R E+ ++ Y + ++ +I ++ + + A KVF ++AL+ + F P+ I + EA VSIKR+ FL + + DE S +ET I I+ + A++ + TL+N+ + K + V ++GPVGSGKT+ L A+LGE+ G+I+++ LS Y Q PW+ + S+R NILFGE ++ KY K ++ L+HD GD T+ GE+G ALSGGQKAR++LARAIY+D DIYL+DD S++D VG +Y + + LK K IL TH QY+ DA++++ +K G E T L+ + T DFS
Sbjct: 236 QEDTSIMDXXFFKWXSPLIDKGRMGKLNSSQDVFDLPHNIHTGIV-------YEDFEFHKSRVRSLQWFRKALSSKFLKEFLCIGMIKFVADVSGFFC-PLLLNRLVKFMEDPKADLRW--GYFYAFSLFVSTFLVAICNTQFNFKMNELGLKVRASVIQSLYKQTLSVSEANLNKYSRGEIINFMSIDVDRVVNFAPSFHAFWSLPFQMVVTLYLLHQQVGVSSFVGVGFAILMIPINKVIATKIGSLSGHMMSAKDDRVKIIAEIIEGIRVIKYYCWESFFTDKTNSHRNNEIYYLKWRKYLDAVCVYLWASTPVIISVSTFATYSALGNPLTAAKVFTSMALFAMLSGPFNAF-PFVINGLIEANVSIKRLARFLSLPSINRIKYFTEYKDENTKASKEIETKIP-DIQIMEASFGF-TKDCFTLRNIDVSIKRQEFVGVLGPVGSGKTTFLNAILGELEKQSGKISVRDPLSGIAYVQQVPWIQNKSIRDNILFGEMYIHGKYTKVIKACCLDHDFKHLHRGDHTIAGEKGAALSGGQKARIALARAIYQDKDIYLIDDVFSSLDVNVGYKVYTEVMLNLLKRKTRILCTHNPQYINDANIVIKIKDGEFESVKQSTHLVPTSTSPDFS 855 HSP 3 Score: 93.5893 bits (231), Expect = 2.557e-19 Identity = 97/392 (24.74%), Postives = 182/392 (46.43%), Query Frame = 0
Query: 275 MSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAM---VSEALVSIKRIQDFLLMGERDATSSHGRIHDESPP--METPISVSIKGLTATWD----HQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQG-----------RLSYAA--QEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDR---TMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSS-GTDFSEFIPE 640
+E ++G+K+I+ F +E+ + A + F+ S + ++ +I++ + VIN E V L + L V Y + M ++E +VS + L+ ER A RI++ES + P + +G+ D ++ L + + K + + IVG G+GK+S++ AL GEI + G R +A Q+P++FSG++R N+ +++ ++++S L + I + FG T++G+ G +LS GQK + LARAI A + +D+ ++VD + + L ++T K VI + H+I+ + ++D I V+ G I G +L+ S ++F + I +
Sbjct: 1081 FNETVHGLKIIRASKASQRFL-----LENEELVECNQKARYAAFSASLWLEIRLQLIGSIVVFSIALISVINFESVDAGL---------VGLAVSYALGMTXRLAEVVVSFTETEKELVAVER-AYDYIDRIYEESYSGVLNMPYNWPNQGVVEFKDIRLRYKDHLPYVLNKVNFKTKPKEKIGIVGRTGAGKSSLIAALFRLSSFSHGEIMVDGIRIRLLPLIDFRRQFAVIPQDPFIFSGTIRQNLDPYAQHSDQELWDSIKLSYLYNII--YSFGSSGLDTLIGDGGKSLSIGQKQLLCLARAIITSAKVVFIDEATASVDKETDR-LIRNVLKTAFNDKTVITIAHRIETVLNSDRIFVMSNGQIIEEGKPEDLIKSPNSEFRKLIEQ 1454 HSP 4 Score: 65.4698 bits (158), Expect = 9.364e-11 Identity = 49/202 (24.26%), Postives = 96/202 (47.52%), Query Frame = 0
Query: 1123 LKGVDFVTKSKEKIGIVGRTGAGKSSLIVALF-RLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWI-QETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSS 1322
L+ +D K +E +G++G G+GK++ + A+ L + +G+I V + I+ + Q P + + S+R N+ Y + + +K LD + + +G T E G+ LS GQ+ + LARAI ++ I ++D+ +++D + E + T + H + D++ ++ + DG EF S
Sbjct: 650 LRNIDVSIKRQEFVGVLGPVGSGKTTFLNAILGELEKQSGKISV----------RDPLSGIAYVQQVPWIQNKSIRDNILFGEMYIHGKYTKVIKACCLDHDFKHLHRGDHTIAGEKGAALSGGQKARIALARAIYQDKDIYLIDDVFSSLDVNVGYKVYTEVMLNLLKRKTRILCTHNPQYINDANIVIKIKDG---EFES 838
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000002016 (supercontig:LSalAtl2s:LSalAtl2s1361:43077:48755:-1 gene:EMLSAG00000002016 transcript:EMLSAT00000002016 description:"augustus_masked-LSalAtl2s1361-processed-gene-0.2") HSP 1 Score: 279.641 bits (714), Expect = 1.780e-76 Identity = 179/653 (27.41%), Postives = 321/653 (49.16%), Query Frame = 0
Query: 729 ESAALGSVSLGTYWSYFRSGAHSLVLLA--VLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWL--VVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESE----ADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKE-----------------------------------KIGIVGRTGAGKSSLIVALFRLTEP-TGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSEL 1337
E+ GS+ +G YF++G + LA +IL+ Q + ++D L W+ M E ++ ++ S +G +++ ++++S V + L+ + LH DM + I+ P F+ P+GR++NR S D+ +D+ +PP + +I + + + P+ M ++ L +Y SSR ++R + I ++P+ S + +L GL ++RA+ ++ I+E D +TSA+ + RW G++LD + ++L V F F G + S +G+ + +++ L W ++ A +EN M + ERVLEY SE ++ + H M S R ++ R ++ E E+ V DF+ E K+GI GR+G+GKS+L++ + RL+ G I ++G+NI I L LR + IPQD ++F G++R NLDP N++ D IW L +A + +R+ P G++T ++E G N S GQRQ + + +A+LR +++ILDE+T+ +DP + + T+ + F D T++++AHRL +++ +R+LVM +GR+ E +P +LL+ S L
Sbjct: 1271 ENREYGSIDIGVLTVYFKAGG---IFLAGFFVILSFVLQSVKVYMDFLLRDWS------MEEKNSDKLIAYFS------------------FYGSLSVIVILISCVANLIGQLIGARARTKLHNDMIQNIMYCPLELFEAFPIGRIINRISHDIFIVDQKIPPCIQRLIMLSFVCIAALAXNSIQSPVFLIFALPMISIYWWLXHFYRRSSRELQRLDSITRAPVLSHFSDTLSGLITVRAFGEQTRFINELCEKVDTNTSAFLILQSGCRWLGVYLDAAGAIFVFLSILVNLF-FPRKGRE-------VTSSASIGLSVNYSLLVPIYLAWVVKFAANIENYMNAVERVLEYTHFPSEEEDFSEFQAVHASSM---NSSRRSFLLRGRG---KHDEIEEDVRVSGDFLQNDSEGLIIRFNSVCLAPSFEYRRLPGIQQGFSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFEDSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGFFSAL 1882 HSP 2 Score: 187.963 bits (476), Expect = 4.531e-48 Identity = 177/715 (24.76%), Postives = 320/715 (44.76%), Query Frame = 0
Query: 17 ASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKSEPSLLRAVIKTFGGEFGFLG-MFTFFEE-----CGIRIA-----------------------QPL-----FLSWFVS--YFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRV-GMRVRITLSALIYRKALRLSSAS----------------------MGKST-------------VGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSV-PLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVL-SNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPME--------------------------TPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEI--NIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHL--KPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTEL 627
AS S FWWLNP+L GY+ LE++DL + + + ++ KL+ + + S+L I T F LG +F F + C + I PL + S+FVS +F P RV + + L + AL ++H ++ V G+R + L L+Y K+L+L S MG S +G + NL + D+ +HY+WA PL++++++ L + ++G S ++GA + C + PLQ G++ S D R+ +E + +K +K+ E K ++ R KE+ +RR ++ F ST ++ L FVL + A +F ++AL + + + +++ VP + + + VS +R+ +FL E + +++ + +++ T W + L+++ L+ K G + ++GP GSGKT+++ +L+ E+ G + N+ ++ Q PW+ + +++ NIL G F EK+Y K + L+ DI GD T +GERGV LSGGQ+ R+++AR +Y + +D P S++D+++ +++E+ + L + + V L T ++ +L AD IV LK G I+ +GT ++
Sbjct: 250 ASSFSRLTFWWLNPILTQGYRAPLEIDDLHKLPKEERTKKYFQKLKTLLS--------RDKSSILWECI-TMNWSFVILGGLFRLFADILGYACALSINIIVNSIAAENENASLHLISNVTINPLKDTRYYDSFFVSELFFDP------RVVSIVIFLAALGQGALSQTSNH-----LLTVSGIRAKNALHVLLYEKSLKLPVGSSNPMQIHRKINLKPLNDEGKGCMGGSCSLDEDYSNEGNIDIGFITNLASEDIINIRELIWNVHYIWALPLKILVLLFLLYDQLGISGVSGAILGTCVILPLQVLTGKLMSENNKLILCSQDNRLFKSTETLASMKTVKLATMEEWALKRIRCARTKELIFLRRDSFLWSFMAFLASISTTLVTTLTLGLFVLLEDHNFTAADLFTSMALLSQLTVCLSV-VPVTVPIFIKGKVSTQRLAEFLNRAEVSIYKQNNKLNKHCTYFDDRKDDDEEEEEEEEESEIFIQRAKRLPETCFTVENGTFAWPKCET--NVLQSINLEIKTGSLTIVIGPSGSGKTALISSLIEEMDRITGSVKWNVPDTVALLGQRPWLLNTTIKDNILLGRPFKEKRYKKVIAACDLQTDIDLLPHGDDTEIGERGVLLSGGQRQRLAIARCLYSKSYCTFMDAPFSSLDSKITSHVFEEGVLKILLKRRRTVFLTTERLDFLHRADHIVALKDGMIKAQGTIQDV 941 HSP 3 Score: 65.0846 bits (157), Expect = 1.393e-10 Identity = 63/286 (22.03%), Postives = 131/286 (45.80%), Query Frame = 0
Query: 1103 EGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFR-LTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRT------DGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQNKPFMEDEEYAEAEEMNLQVT 1381
E N + + E +VL+ ++ K+ ++G +G+GK++LI +L + TG + N+ + ++++ Q P + + +++ N+ +++ + + + L I +P G +TE+ E G LS GQRQ + +AR + + +D +++D + +G ++ +++R TV RL + +D I+ + DG + + +QD + EL+ ST+L R++R S NK +E + E ++ VT
Sbjct: 725 ETCFTVENGTFAWPKCETNVLQSINLEIKTGSLTIVIGPSGSGKTALISSLIEEMDRITGSV---KWNVPD--------TVALLGQRPWLLNTTIKDNILLGRPFKEKRYKKVIAACDLQTDIDLLPHGDDTEIGERGVLLSGGQRQRLAIARCLYSKSYCTFMDAPFSSLDSKITSHVFEEGVLKILLKRRR---TVFLTTERLDFLHRADHIVALKDGMIKAQGT----IQDVTRLCPELL-----STKLSKNRLSRIS--DDNKGLVEGKTAQERWKLLRNVT 985 HSP 4 Score: 62.7734 bits (151), Expect = 6.515e-10 Identity = 53/212 (25.00%), Postives = 95/212 (44.81%), Query Frame = 0
Query: 436 KNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQG---------RLS----YAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDF 634
+ L+ Q V I G GSGK+++L ++ QG I I G RL Q+ +FSG++R N+ F ++ TL+ + + + G T V E G S GQ+ +++ +A+ R + +LD+ SA+D L+ ++ + +I V H++ + + + ++V+ +G I G ELL F
Sbjct: 1668 QGFSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEA-FEDSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGF 1878
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000000090 (supercontig:LSalAtl2s:LSalAtl2s1014:9799:23913:-1 gene:EMLSAG00000000090 transcript:EMLSAT00000000090 description:"maker-LSalAtl2s1014-snap-gene-0.6") HSP 1 Score: 200.29 bits (508), Expect = 7.160e-53 Identity = 164/624 (26.28%), Postives = 277/624 (44.39%), Query Frame = 0
Query: 742 WSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNL--IIFGGMTLALVIMSLVRTIHFFL-------MCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILG--IVGVIVFYQPIV-FFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLA-SSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMF-----QPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTE-PTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQ 1346
+ Y+ ++ + L+ L +Q +WL WTN +SS + I + RN+ +++G I+ +++ +FL +S + H + +K+ AP FF P G ++NRFSKDM D LP L + + ILG I+ +I F PI FF C + ++F+ + K YL +SR +KR+ + + S++ G T+IR Y ES I E + D H S + + L L + ++G +F S + VL + T R A +E M S ER+ E + + D P + +P++ I+ + +Y + +K + EK+G+VGRTG+GKSSLI+AL L E G+I +DGV++ +R + D +F GS+R NLDP + + D IW L EA + + +P G++ + E GSN+S L + ++I+DEA + + ++ I T RF+ T+ IAHR+ ++ D+ILV+ +G +AEF +P L++ + S+ ++ S +
Sbjct: 309 YKYYVLNLGTVPFIIALVGYLISQCFDVCSKLWLSRWTN--------------LSSTNINDTNYRHIYNEDTRNMYIVVYG-------ILGWCQSLAYFLSVLLINSRSLKASSHFHDVILRKVFGAPLNFFWSTPKGTIINRFSKDMDEADMFLPNTLKNFAYQAVKILGTLIIALIAF--PITAFFIVCPLGLIFIEVVKSYLMASRFLKRTSATKLAMVLKHFGDSAVHGGTTIRCYGVESDYIDEHMSLIDEHQSVSLMEIISEAXLFLRLQLIAGTFIGILATALVFFP--SEGNSSSLSALSLTSSLTVLQDIFLFT-------RYAAFIEKAMVSIERIKECEDLIPQ-DPSSGLLPSIITNGSKRPKNHQSRYYIQFEDFSGKYSSLKNASIKNFTLNVRLGEKVGVVGRTGSGKSSLILALSGLLEVEKGKIFIDGVDMSSGTARNIRKKD---ITDAALFKGSIRYNLDPDDRFTDEYIWSVLDEAQMKEFFVQLPGGLDFSLKENGSNIS-------------LAGSNLIIMDEAXSAMTLESEERILNTYFSRFSSSTIFVIAHRIQPLLACDKILVLENGTIAEFGNPESLIKSQKSIFKSMLRRTNGSVE 883 HSP 2 Score: 154.451 bits (389), Expect = 3.102e-38 Identity = 89/266 (33.46%), Postives = 144/266 (54.14%), Query Frame = 0
Query: 367 FVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPT-DQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCI--QTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLS 629
+P I+ +S+ +VSIKRI +L E D+ S+ +SP E S+ ++ + D LKN+ + G++ A+VG VGSGK+ +L AL GE+ +G I L Y Q W+ S ++R NI FG+ + +Y K + + L D GD T + G LSGGQ+ R+ ARAIY++A +YL+DDPLSA D+ + ++ I + L+ K +L+T+Q + D I+V++ G++E + + E+ S
Sbjct: 7 LLPSCISALSQGIVSIKRIDSYLNREEVDSVKSND--FSKSPRPEDGYSIQVQDCNYSIDKL----KLLKNINFSTRVGELTAVVGKVGSGKSCLLAALCGELNQRGKGSSLINKDLVYVTQNIWLKSATIRDNITFGQPYNSSQYQKVVSLCQLGQDFKDMYRGDLTYLASNGSTLSGGQRQRIGFARAIYQNAQVYLMDDPLSACDSNLKAQIFHNTIGPKGFLQKKTRLLITNQSSLIPLMDRIIVIQNGTVEEKDSAEEVKS 266 HSP 3 Score: 79.337 bits (194), Expect = 5.041e-15 Identity = 66/255 (25.88%), Postives = 114/255 (44.71%), Query Frame = 0
Query: 1068 MTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWI-QETIRKR--FADCTVLTIAHRLHTVMDSDRILVMSDGRVAE 1319
+ S +R+ Y E +K + +PE V +C Y + +LK ++F T+ E +VG+ G+GKS L+ AL GE+ N + G + + + Q+ + ++R N+ Y +Q + + L Q + M +G T ++ GS LS GQRQ + ARAI +N ++ ++D+ + D I TI + T L I ++ + DRI+V+ +G V E
Sbjct: 19 IVSIKRIDSYLNREEVDSVKSNDFSKSPRPEDGYSIQVQDC-----NYSIDKLKLLKNINFSTRVGELTAVVGKVGSGKSCLLAAL------CGEL-----NQRGKGSSLINKDLVYVTQNIWLKSATIRDNITFGQPYNSSQYQKVVSLCQLGQDFKDMYRGDLTYLASNGSTLSGGQRQRIGFARAIYQNAQVYLMDDPLSACDSNLKAQIFHNTIGPKGFLQKKTRLLITNQSSLIPLMDRIIVIQNGTVEE 257 HSP 4 Score: 61.2326 bits (147), Expect = 1.944e-9 Identity = 71/288 (24.65%), Postives = 130/288 (45.14%), Query Frame = 0
Query: 366 LFVPYGIAMVSEALVSIKRIQDFLLMGERDATSS--HGRIHDESP-PMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQG-RLSYAA---------QEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGG-------QKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH---LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSS 630
LF Y A + +A+VSI+RI++ + +D +S I + S P I+ + + + +++KN L + G+ V +VG GSGK+S++ AL G + ++G+I I G +S + +F GS+R+N+ + F + +Y+ W D + E V L GG + +SLA +++ ++D+ SA+ + E+ + T+ + ++ H+IQ L D I+VL+ G+I G L+ S
Sbjct: 604 LFTRYA-AFIEKAMVSIERIKECEDLIPQDPSSGLLPSIITNGSKRPKNHQSRYYIQFEDFSGKYSSLKNASIKNFTLNVRLGEKVGVVGRTGSGKSSLILALSGLLEVEKGKIFIDGVDMSSGTARNIRKKDITDAALFKGSIRYNLDPDDRFTD-EYI--------------WSVLDEAQMKEFFVQLPGGLDFSLKENGSNISLA-----GSNLIIMDEAXSAMTLESE----ERILNTYFSRFSSSTIFVIAHRIQPLLACDKILVLENGTIAEFGNPESLIKS 866
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Match: EMLSAG00000003104 (supercontig:LSalAtl2s:LSalAtl2s174:364234:370462:-1 gene:EMLSAG00000003104 transcript:EMLSAT00000003104 description:"maker-LSalAtl2s174-augustus-gene-3.18") HSP 1 Score: 159.073 bits (401), Expect = 1.473e-39 Identity = 84/212 (39.62%), Postives = 134/212 (63.21%), Query Frame = 0
Query: 1119 EKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFN-EYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQ 1328
+K++ G+ F +S + I IVG +G+GKS+L+ L+R EP G I + NI E+ L LR QISI+PQD ++F+ ++ N+ N D +++ K A +D AIRS PQG T++ E G LS G++Q V +ARA L+++ I+I DEAT+++D T+ I + +++ + T + IAHRL TV+ +D I V+S+G+V E + +LL
Sbjct: 376 DKNIANGLSFSVESGKTIAIVGESGSGKSTLVRLLYRFYEPQLGSIKIGNYNINEVTLDSLRRQISIVPQDCVLFNDTIFHNIKYGNLNCSDEDVYKVAKLAEIDNAIRSWPQGYLTQVGERGLKLSGGEKQRVAIARAALKDSPIIIFDEATSSLDSITETMIMKALKRVTSGKTAIIIAHRLSTVVHADEIFVLSNGKVIERGTHEELLN 587 HSP 2 Score: 106.301 bits (264), Expect = 3.181e-23 Identity = 70/227 (30.84%), Postives = 124/227 (54.63%), Query Frame = 0
Query: 424 TWDHQAQGESTLKN----LGLQAKAGQMVAIVGPVGSGKTSILQAL-------LGEIPTDQGEIN------IQGRLSYAAQEPWVFSGSVRHNILFGE-TFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGT 632
T+D G + KN L ++G+ +AIVG GSGK+++++ L LG I IN ++ ++S Q+ +F+ ++ HNI +G ++ K +++ +++ I W G T VGERG+ LSGG+K RV++ARA +D+ I + D+ S++D+ + + + K ++ K I++ H++ + AD I VL G + RGT+ ELL++ T
Sbjct: 365 TFDDVKFGYNIDKNIANGLSFSVESGKTIAIVGESGSGKSTLVRLLYRFYEPQLGSIKIGNYNINEVTLDSLRRQISIVPQDCVLFNDTIFHNIKYGNLNCSDEDVYKVAKLAEIDNAIRSWPQGYLTQVGERGLKLSGGEKQRVAIARAALKDSPIIIFDEATSSLDS-ITETMIMKALKRVTSGKTAIIIAHRLSTVVHADEIFVLSNGKVIERGTHEELLNTLT 590
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|206729914|sp|O15439.3|MRP4_HUMAN (RecName: Full=Multidrug resistance-associated protein 4; AltName: Full=ATP-binding cassette sub-family C member 4; AltName: Full=MRP/cMOAT-related ABC transporter; AltName: Full=Multi-specific organic anion transporter B; Short=MOAT-B) HSP 1 Score: 1140.95 bits (2950), Expect = 0.000e+0 Identity = 600/1373 (43.70%), Postives = 864/1373 (62.93%), Query Frame = 0
Query: 10 RENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQV-EDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFA--PGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQNKPFMEDEEYAEAEEMNLQ 1379
+ NP ++A+ S FFWWLNPL ++G+K+ LE +D++ L D S+ L +LQ WD +V E +PSL RA+IK + + LG+FT EE ++ QP+FL ++YF +SV AY Y + + + HH YF+ V GMR+R+ + +IYRKALRLS+ +MGK+T GQ+VNLL+NDV++FD +F+H+LWAGPLQ I V L W E+G S LAG ++I +PLQS G++FS LR +TA TD RIR M+E+I GI++IKMYAWE F+ ++ + R+KE+ I R++ RG N + FF+++K+I+ +VL VI A +VF+ + LY VRL++TLF P I VSEA+VSI+RIQ FLL+ D S R P + V ++ TA WD +A TL+ L + G+++A+VGPVG+GK+S+L A+LGE+ G +++ GR++Y +Q+PWVFSG++R NILFG+ + +++Y K ++ AL+ D+ E GD T++G+RG LSGGQKARV+LARA+Y+DADIYLLDDPLSAVDA+V ++L+E CI L K+ ILVTHQ+QYLK A I++LK G + +GTYTE L SG DF + + EE S+ VP T +R+R++S S +DG ++ E+ P L + N + G V Y +YFR+GAH +V + +++LN A Q + D WL W N++ + N T++ + T ++ +N L I+ G+T+A V+ + R++ F + +SS LH MF+ I++AP FFD NP+GR+LNRFSKD+G +D+LLP D I L ++G+V V V P + P + ++F+ LR+Y+L +SR +KR E +SP+FS L+SSL GL +IRAYKAE FD QD+H+ AW+ FL T+RWF + LD C I + GS + + +G VG+ L+ + L GM QW +RQ+AE+EN+M S ERV+EY +E EA + P P +WP EGVI NV Y G VLK + + KS+EK+GIVGRTGAGKSSLI ALFRL+EP G+I +D + EIGLH+LR ++SIIPQ+P++F G++RKNLDPFNE+ D ++W AL+E L + I +P ++TE++E GSN S GQRQLVCLARAILR N+ILI+DEATANVDPRTD IQ+ IR++FA CTVLTIAHRL+T++DSD+I+V+ GR+ E+ PY LLQ++ S+ ++V +G++ L A++ + ++N P + ++ N Q
Sbjct: 9 KPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESA-KVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLL---DEISQRNR----QLPSDGKKMVHVQDFTAFWD-KASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEE------------------SEQPPVPG------TPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENR---------SEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQ------SMLNVTVNGGGNVTEKLD-LNWY----LGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLD-------AICAMFVIIVAFGS---LILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRP----PPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQ 1314
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|1018447391|sp|P91660.4|L259_DROME (RecName: Full=Probable multidrug resistance-associated protein lethal(2)03659; AltName: Full=Wunen region A protein) HSP 1 Score: 1035.79 bits (2677), Expect = 0.000e+0 Identity = 550/1366 (40.26%), Postives = 830/1366 (60.76%), Query Frame = 0
Query: 11 ENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFA--PGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDAT-SSHGRIHDE---SPPMET------PISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSG--TDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKV--DHHPDMFQPESWPREGVIECRNVRLQYGEGEK--HVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHS-VLSELVSNVGRSTQLELRRIARESF 1357
ENPR ++F+S FW+ P+ R GY+K L+ DL+RPL S++L N+L W+ +++++ R PSL+RA+++ FG + GF G+ F E G+R QP+FL +SYF+ P + G + Y + +++SAL P FG+ V ++R+ + ++I+RKALRL+ ++G +T G +VNL++ND+ R DSA +HYLW GPLQ++++ L ++E+G S + G ++ +P+Q ++G S ++L+ A++TD RIR+++EII+ I+V+KMYAWE PF ++V REKEM+ IR+ Y RGF+F+ ++V + L+ +V+ +V E F+ A YN + +M+++VP I ++ L SI+R++ F+ E ++ S G D +PP ++SI+ L A WD + + TL + L+ K G +VA++G GSGK+S++QA+LGE+ + G++ + G LSY +QE W+FSG+VR NILFG+ ++Y + ++ ALE D D T+VGERG LSGGQKAR+SLAR++YR A IYLLDDPLSAVDA V ++L+++C++ HL+ V+LVTHQ Q+L D IV+L G I+ G Y LL +G T + D A + E LN L +P ++ + E+ + +G ++S K H E G +SL Y YF++G + L +L ++ Q T D +L W +E + + S + D K LII + VIM+L + F + K +S+ LH +F ++ RA FF IN G +LNRF+KDM +DE+LP VL DV+ I L + GI+ VI P++ PT +++V+F LR YL +SR +KR E I +SP++S LA+SL GLT+IRA A+ +L EFD QD H+SA++ +++T++ FG ++ + V+Y+ +F G+ DVG+V+T + L M+QWG+RQTAE+EN MT+ ERV+EY IE E L+ D P P++WP +G I + + L+Y K +VLK + FV + +EK+GIVGRTGAGKSSLI ALFRL+ G +L+D + +++GLH+LR QISIIPQ+P++F G++R NLDPF+EY D ++W L+E L + + +P G+ +++SEGG+N S GQRQLVCLARAILR N+IL++DEATANVDP+TDG IQ TIR +F DCTVLTIAHRLHT++DSD+++VM GRV EF SPY+L+ S V LV+ GR++ L +IA+E+F
Sbjct: 88 ENPRARSNFISSLCFWYTIPIFRKGYRKTLDSTDLYRPLEEQKSDILGNRLCASWERELKNDGRS--PSLVRALLRVFGWQLGFPGLAIFVVELGLRTLQPIFLVKLISYFSGEPDAANAG----FYYAVAQIVISALTVMILTPTTFGIHHVCFKMRVAMGSMIFRKALRLTKGALGDTTSGHVVNLISNDIPRLDSAPYTVHYLWVGPLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRTSAIQLKAAERTDNRIRMVNEIISAIQVLKMYAWEQPFEQMVTHAREKEMNTIRQGQYIRGFDFARRIVLSRVAIFLSLVGYVILGKVFTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRRVEQFMQSEELGSSDKSEGPSKDTVPGNPPSNNNEADLLKSAISIRDLKAKWDPNSP-DYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNGSLSYTSQESWLFSGTVRQNILFGQPMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGDYESLLKTGLITGLGSL-----SKTDKAKTEEQEPLN-LNSP--------------------------------------DNKNEVTPIKENSEQTVGGSSS-GKEHVERQESGGISLALYRKYFQAGGGLVAFLVMLSSSVLAQVAVTGGDYFLTYWVKKESTAAGHGEMEDMESKSMD----------VYKYTLII-----ILSVIMNLSSSFLLFNIAKKASIRLHNTIFNRVTRADMHFFSINKHGSILNRFTKDMSQVDEVLPVVLVDVMQIALWLAGIIIVIANVNPLLLVPTLMLSVIFYHLRNLYLKTSRDLKRVEAINRSPVYSHLAASLNGLTTIRALDAQRVLEKEFDSYQDAHSSAFFMYISTSQAFGYCMNCICVIYISIITLSFFAFPPGNG-----------ADVGLVITQAMGLIDMVQWGVRQTAELENTMTAVERVVEYESIEPEGMLEAPDDKKP----PKTWPEQGEIIFKELNLRYTPNAKAENVLKSLSFVIQPREKVGIVGRTGAGKSSLINALFRLSYTDGSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTMRYNLDPFDEYSDEKLWGCLEEVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQATIRSKFRDCTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYELMTKSDSKVFHNLVNQSGRASYEGLLKIAQETF 1371 HSP 2 Score: 83.1889 bits (204), Expect = 1.360e-14 Identity = 75/333 (22.52%), Postives = 156/333 (46.85%), Query Frame = 0
Query: 1040 VGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYG-EGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALF-RLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQ-ALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWI-QETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQNKPFMEDE 1368
+ + + S I+ T +R+ +E M S E + K E + V +P E+ + I R+++ ++ + L G++ K + ++G TG+GKSSLI A+ L +G++ V+G +S Q+ +F G++R+N+ F + D+Q ++ +K+ L++ +P T + E G+ LS GQ+ + LAR++ R I +LD+ + VD + + +R TV+ + H+ + D+I+++++G++ LL+ + L++ +G ++ + + + L N P ++E
Sbjct: 437 MSIYVPSAIIQTAQFLTSIRR---VEQFMQS-EELGSSDKSEGPSKDTVPGNPPSNNNEADLLKSAISIRDLKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNG-------------SLSYTSQESWLFSGTVRQNI-LFGQPMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGDYESLLK------TGLITGLGSLSKTDKAKTEEQEPLNLNSPDNKNE 745
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|52783101|sp|O35379.1|MRP1_MOUSE (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 792.727 bits (2046), Expect = 0.000e+0 Identity = 477/1372 (34.77%), Postives = 744/1372 (54.23%), Query Frame = 0
Query: 13 PRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKS---------------------------------------EPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQ--VINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGES-TLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH--LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEI-RHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTL----ALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQ----SGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDR 1330
P +ASFLS FWW+ ++ GY++ LE +DL+ + D SE + L +W + D++RK EPSL + + KTFG F ++ + + A P L +++ + Y Y + + + L T H YF GMR++ + +YRKAL +++A+ STVG++VNL++ D RF +I+ +W+ PLQ+IL + W +G S LAG ++I VPL + + ++ K D RI++M+EI+NGIKV+K+YAWEL F V R++E+ V++++AY + + ++ L+ FV ++ +++A+K F++LAL+N +R + + +P I+ + +A VS+KR++ FL E + S I S S+++K T TW A+GE TL + G +VA+VG VG GK+S+L ALL E+ +G + ++G ++Y Q+ W+ + S+R NILFG E Y +E AL D+ GDRT +GE+GV LSGGQK RVSLARA+Y ++DIYL DDPLSAVDA VGK+++EK + LK K ILVTH I YL D+I+V+ G I G+Y ELL F+EF+ + + D + D D ++ S P VT + +H + + S S S+ S+AE ++ KE + + + A G V L YW+Y ++ + L++ + L + WL +WT D+ P + A+ L ++G + + A+ S+ +I +S LH D+ ++R+P FF+ P G ++NRFSK++ ++D ++P V+ + S++G V +I+ PI + +++ ++++Y++SSR +KR E +++SP++S +L G++ IRA++ + I + D D + A+Y + RW + L+ CVG I + A+F+V S+ +G VG+ ++ + +T L W +R ++EME + + ER+ EY + E EA ++ + P +WP G +E R+ L+Y E VLK ++ + EK+GIVGRTGAGKSSL + LFR+ E GEI++DGVNI +IGLH LR +I+IIPQDP++F GSLR NLDPF++Y D ++W AL+ AHL + ++P + E +EGG NLS GQRQLVCLARA+LR KIL+LDEATA VD TD IQ TIR +F DCTVLTIAHRL+T+MD R++V+ G V E +P +LLQ R
Sbjct: 209 PESSASFLSRITFWWITGMMVHGYRQPLESSDLWSLNKEDTSEEVVPVLVNNWKKEC-DKSRKQPVRIVYAPPKDPSKPKGSSQLDVNEEVEALIVKSPHKDREPSLFKVLYKTFGPYFLMSFLYKALHDL-MMFAGPKILELIINFV--NDREAPDWQGYFYTALLFVSACLQTLALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNI-LPMVISSIVQASVSLKRLRIFLSHEELEPDS----IERRSIKSGEGNSITVKNATFTW---ARGEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFLRTYANAEQDLASED-----DSVSGSGKESKPVENGMLVTDTVGKHLQRHLSNSSSHS--GDTSQQHSSIAELQKAGAKE----ETWKLMEADKAQTGQVQLSVYWNYMKAIGLFITFLSIFLF-LCNHVSALASNYWLSLWT--------------------DDPPVVNGTQANRNFRLSVYGALGILQGAAIFGYSMAVSIGGIF----ASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLE---------CVGNCIVL-----FAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ---ETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQR 1515
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|82231164|sp|Q5F364.1|MRP1_CHICK (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 785.408 bits (2027), Expect = 0.000e+0 Identity = 461/1366 (33.75%), Postives = 739/1366 (54.10%), Query Frame = 0
Query: 13 PRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQ------------------------------------VEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVL--SNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH--LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASV---TSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQS----GDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDR 1330
P +ASFLS FWW+ L+ G+++ LE DL+ + D SE + L ++W + ++ R SE SL + + KTFG F +F + + P L +++ S + Y Y + + + L T H YF GMR++ + +IYRKAL +++++ STVG++VNL++ D RF +I+ +W+ PLQ+IL + L WR +G S LAG ++I VP+ + + ++ K D RI++M+EI+NGIKV+K+YAWEL F + V + R+KE+ V++++AY + + ++ L+ +V N +++A+K F++LAL+N +R + + +P I+ + EA VS+KR++ FL E D S P S+ +K T +W +L ++ G ++A+VG VG GK+S+L ALLGE+ +G + ++G ++Y Q+ W+ + ++ NI+FG E +Y + +E AL D+ GDRT +GE+GV LSGGQK RVSLARA+Y +AD YL DDPLSAVDA VGK+++EK I LK K +LVTH + YL D I+V+ G I G+Y ELL F+EF+ + + + D +PS P V T ++ HR S + S S S+ S AE K L + NS ++A G V YW Y ++ + L+V + + + WL +WT+ P + L ++G + ++ I ++ + +S +LH D+ ++R+P FF+ P G +++RFSK++ +ID +PP++ + +++G +I+ PI + +++++++++Y+++SR +KR E +++SP++S +L G++ IRA++ + I + D D + A+Y + RW + L+ ++G C+ F A+F+V +++ G +G+ ++ + +T L W +R T+++E + + ERV EY ++E EA+ ++ + +WP+EG +E R L+Y E VLK ++ EK+GIVGRTGAGKSSL + LFR+ E GEI++DG+NI +IGLH+LR +I+IIPQDP++F GSLR NLDPF+++ D IW++L+ AHL + S+P + E SEGG NLS GQRQLVCLARA+LR +KIL+LDEATA VD TD IQ TI+ +F +CTVLTIAHRL+T+MD R+LV+ G V E SP +LLQ +
Sbjct: 209 PEFSASFLSRITFWWITGLMIQGHRRPLEAKDLWSLNKEDTSEEIVPGLAKNWAKEWAKTKRQPLNMLYSSKKQQKSSDSNGEVMEEAEALIIKPSQRSSEASLSKVLYKTFGPYFLMSFLFKAAHDL-LMFTGPEILKLLINFV--NNKSAPNWQGYFYTGLLFVCACLQTLILHQYFHICFVTGMRLKTAIVGVIYRKALVITNSARKTSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPSVLAGVAVMILLVPINAVMAMKTKTYQVAQMKSKDNRIKLMNEILNGIKVLKLYAWELAFREKVLEIRQKELKVLKKSAYLAAMGTFTWVCAPFLVALSTFAVYVKVNKNNILDAQKAFVSLALFNILRFPLNI-LPMVISSIVEASVSLKRLRVFLSHEELDPDSII-----RGPITNAEGSIVVKNATFSWSKT--DPPSLNSINFTVPEGSLIAVVGQVGCGKSSLLSALLGEMDKKEGYVVVKGSIAYVPQQAWIQNATLEDNIIFGREMNESRYKRVIEACALLPDLEILPMGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADTYLFDDPLSAVDAHVGKHIFEKVIGPKGILKNKTRVLVTHAVNYLPQMDTILVMTDGEISEMGSYQELLKQDGAFAEFLRTYANAEQSMESSDAS------SPSGKEGKPVENGVLVNDATGKLMHRQLS--NSSTYSRETGKSQHQSSTAELQ----KPLAEKNSWKLTEADTAKTGRVKATVYWEYMKAIGLYISFLSVFLF-MCNHIASLASNYWLSLWTDD---------------------PVVNGTQQYTNVRLGVYGALGISQGIAVFGYSMAVSIGGIFASRHLHLDLLHNVLRSPMSFFERTPSGNLVSRFSKEIDTIDSTIPPIIKMFMGSTFNVIGACIIILLATPIAAVVIPPLGLVYLLVQRFYVATSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQKRFIKQNDMKVDENQKAYYPSIVANRWLAVRLE-----FVGNCIVLF---------AALFAVIARNKLSPGLIGLSVSYSLQITAYLNWLVRMTSDLETNIVAVERVKEYAEMEKEAEWSIE---ETAPASTWPQEGKVEFRGFGLRYREDLDLVLKNINITINGGEKVGIVGRTGAGKSSLTLGLFRINEAAEGEIIIDGINIAKIGLHDLRFKITIIPQDPILFSGSLRMNLDPFDQHSDEDIWRSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDNLIQSTIKSQFEECTVLTIAHRLNTIMDYTRVLVLDRGEVVECDSPDNLLQAK 1512
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|218526606|sp|B2RX12.1|MRP3_MOUSE (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 784.637 bits (2025), Expect = 0.000e+0 Identity = 477/1372 (34.77%), Postives = 756/1372 (55.10%), Query Frame = 0
Query: 13 PRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQ-----------------------VEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIP---FVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH--LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFI----PEHTEEDDDAIAGDLEHLND-LMAPSDTLCVPRRFSASVTS--EIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPK-------------IHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDI----HTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSV-GSQS---GDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLL 1327
P +A F S FWW L LGY++ LE DL+ D S + +L W Q ++ + +PS LRA+++TF F + + P LS + + + + +L + L S + T H Y+ + + +R+R + +IYRKAL ++++ +STVG+MVNL++ D RF FI+ LW+ PLQ+IL + W+ +G S LAG +++ +PL + +++ K D RI++MSEI+NGIKV+K+YAWE F + V+ R+ E+ ++R+ AY + + +F + T ++ I + +V + V++AEK F++L+L+N +++ + + +P I+ +++A VS+KRIQDFL E D E + +++I T TW TL +L +Q G +VA+VGPVG GK+S++ ALLGE+ +G ++++G ++Y Q+ W+ + +++ N+LFG+ K+Y + LE AL D+ GD+T +GE+G+ LSGGQ+ RVSLARA+Y DA+I+LLDDPLSAVD+ V K+++++ I L K +LVTH I +L D I+VL G + G Y+ LL F+ F+ P+ +ED +A L++ N+ ++ DTL + + + E+R + M M ++S +G+ + + PK+ NS+ K I E A G+V L YW Y +S L ++ +L +VWL W+N E Q N T + L I G+ + L ++V + ++ LH + IR+P FFD P GR+LNRFSKD+ IDE+L P + +++ F + + + VIV P+ +AVL+ ++++Y+++SR +KR E I++SPIFS + ++ G + IRAY I +F + D + + Y ++A+ RW G+ ++ ++G CV F A+F+V G S G VG+ ++ + +T L W +R +++E+ + + ERV EY K ++EA V+ + PE WP G++E RN ++Y G + VLK V + EK+GIVGRTGAGKSS+ + LFR+ E GEI++DG+N+ IGLH+LR Q++IIPQDP++F G+LR NLDPF Y + IW+AL+ +HL+ + S P G++ + +EGG NLS GQRQLVCLARA+LR +++L+LDEATA +D TD IQ TIR +F DCTVLTIAHRL+T+MD +R+LV+ G VAEF SP +L+
Sbjct: 208 PEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASGSQTATAEPKIPGEDAVLLKPRPKSKQPSFLRALVRTFTSSLLMSACFNLIQNL-LGFVNPQLLSILIRFIS--DPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAIS-TFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNM-LPQLISGLTQASVSLKRIQDFLNQNELDPQCV------ERKTISPGYAITIHNGTFTWAQDL--PPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEA---ALQNANEEVLLLEDTLSTHTDLTDNEPAIYEVRKQ--------FMREMSSLSSEGEVQ---NRTMPKK--HTNSLEKEALVTKTKETGALIKEEIAETGNVKLSVYWDYAKSMGLCTTL-SICLLYGGQSAAAIGANVWLSAWSNDAEEH---GQQNKT------------SVRLGVYAALGILQGLLVMLSAFTMV------VGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGR----IQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVE-----FVGNCVVLF---------AALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTEAPWVVESNR---APEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLI 1507 HSP 2 Score: 77.411 bits (189), Expect = 7.458e-13 Identity = 60/201 (29.85%), Postives = 97/201 (48.26%), Query Frame = 0
Query: 1136 IGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNL---DPFN--EYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETI---RKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQ 1328
+ +VG G GKSSL+ AL E G+ ++ ++ +PQ + + +L++N+ P N YQ QAL+ L + +P G +TE+ E G NLS GQRQ V LARA+ + I +LD+ + VD I + + A T + + H + + +D I+V++ G+V+E LLQ
Sbjct: 656 VAVVGPVGCGKSSLVSALLGEMEKLE------------GVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQ-----QALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQ 839
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|6016599|sp|O88563.1|MRP3_RAT (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=MRP-like protein 2; Short=MLP-2; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 782.711 bits (2020), Expect = 0.000e+0 Identity = 481/1365 (35.24%), Postives = 747/1365 (54.73%), Query Frame = 0
Query: 13 PRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQV-----------------EDET------RKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVL--SNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDA------TSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH--LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHT-EEDDDAIAGDLEHLND-LMAPSDTLCVPRRFSASVTS--EIRHRSYSVGSESIMSLMMAMSEDGKS-----LAEFDESDPKELGQANSVPK---IHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSV-GSQS---GDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLL 1327
P +A F S FWW L LGY++ LE +DL+ D S + +L W Q EDE + +PS LRA+++TF F ++ S + G G + A L + + S + T H ++ + + +R+R + +IYRKAL ++++ + TVG+MVNL++ D RF FI+ LW+ PLQ+IL + W+ +G S LAG +++ +PL + +++ K D RI++MSEI+NGIKV+K+YAWE F + V+ R+ E+ ++R+ AY + + + + ++ L L +V N V++AEK F++L+L+N +++ + L +P I+ +++ VS+KRIQDFL E D T S GR +++I T +W TL ++ +Q G +VA+VGPVG GK+S++ ALLGE+ +G ++++G ++Y Q+ W+ + +++ N+LFG+ K+Y + LE AL D+ GD+T +GE+G+ LSGGQ+ RVSLARA+Y DA+I+LLDDPLSAVD+ V K+++++ I L K +LVTH I +L D I+VL G I G Y+ELL F+ F+ + +E+ +A G L+H N+ ++ DTL + + + E+R + M M ++S +G+ L + S KE+ + I E A G+V L YW Y +S L + +L + +VWL WTN E + Q NT++ T L I G+ + L ++V + ++ LH + IRAP FFD P GR+LNRFSKD+ I E+L P + + + F + + + VIV P+ +AV + ++++Y+++SR +KR E +++SPIFS + ++ G + IRAY D D + Y ++A+ RW G+ ++ ++G CV F A+F+V G S G VG+ ++ + +T L W +R +++E+ + + ERV EY K E+EA ++ + PE WPR GV+E RN ++Y G + VLK + + EK+GIVGRTGAGKSS+ + LFR+ E GEI +DG+N+ IGLH+LR Q++IIPQDP++F G+LR NLDPF Y D IW+ L+ +HL + S P G++ + SEGG NLS GQRQLVCLARA+LR +++L+LDEATA +D TD IQ TIR +F DCTVLTIAHRL+T+MD +R+LV+ G VAEF SP +L+
Sbjct: 208 PEASAGFFSRLSFWWFTKLAILGYRRPLEDSDLWSLSEEDCSHKVVQRLLEAWQKQQTQASGPQTAALEPKIAGEDEVLLKARPKTKKPSFLRALVRTFTSSLLMGACFKLIQDLSPSSTHSCSASSSGLFRPHGPYWWGFLLAGL----MFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNL-LPQLISGMTQTSVSLKRIQDFLNQDELDPQCVERKTISPGR------------AITIHNGTFSWSKDL--PPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTEPAIYEVRKQ--------FMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKSVGLCTTLF-ICLLYAGQNAVAIGANVWLSAWTNDVEE--HGQQNNTSVRLGVYAT-------------LGILQGLLVMLSAFTMV------VGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVE-----FVGNCVVLF---------SALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSKTETEAPWVLESNR---APEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLI 1506 HSP 2 Score: 80.8777 bits (198), Expect = 6.325e-14 Identity = 67/250 (26.80%), Postives = 113/250 (45.20%), Query Frame = 0
Query: 1093 DMFQPESWPREGVIECRNVRLQYG-----EGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALF-RLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNL---DPFN--EYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETI---RKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQ 1328
D P+ R+ + R + + G + L ++ + +VG G GKSSL+ AL + + G + V G ++ +PQ + + +L++N+ P N YQ QAL+ L + +P G +TE+ E G NLS GQRQ V LARA+ + I +LD+ + VD I + + A T + + H + + +D I+V++DG++ E +LLQ
Sbjct: 607 DELDPQCVERKTISPGRAITIHNGTFSWSKDLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKG-------------SVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQ-----QALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQ 838
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|75017603|sp|Q8ST87.1|ABCCA_DICDI (RecName: Full=ABC transporter C family member 10; AltName: Full=ABC transporter ABCC.10) HSP 1 Score: 782.326 bits (2019), Expect = 0.000e+0 Identity = 465/1380 (33.70%), Postives = 767/1380 (55.58%), Query Frame = 0
Query: 10 RENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAP---GQNSVGRVEAYLYGL---GVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRF-DSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKA--ESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRI--ARESFLRQNKPFMEDEEYAEAEEMN 1377
+++P EN++FLS F W + + ++ L+L+ L+ D SE L K+ + W E E +K +PS LRA + FG + L +F + GI+ P L V++ G ++ Y Y L G ++ + T+ + F R G R+R + +Y+KA++LS+++ ++ GQ+VNL++ND R + +F + A P Q+I+ + L ++++GW T G G+++ ++P + + R +D R++ +EI+ IK+IK+YAWE F K V + R E+ ++ + +R + ++ + + ++A ++F L+ N +RL + F+P IA+ + ++ KR+ DFLL+ E ++P + P V +K T TW+ + LKN+ +A + +VG VGSGK++++QA+LGE+ GEI I+G ++Y Q+ W+ + +++ NI+FG+ E++Y K LEV AL+ DI + GD +GERG+ LSGGQK RVS+ARA+Y DAD+Y+LDDPLSAVD+ VGK+L+ KC + L K VILV +Q+ YL AD VVLK G I RGTY EL++S +FS + E D++ I+ + ++I + + +++D KS PK I E + G+V+ YW Y +G L L++++ L T G TF D WL W + +M S E PT ++ +NL I+ G+ +A V +S+ + ++ +S +H+++F +++ P FFD P+GR++NRF++D+ ID L+ ++ +++ L+++ + ++ P + P ++++F L+ +Y +SR ++R E I +SPIF+ + +L G+ SIRAYK E+ILI++ R+ D + + + + A RW GL LD+L L + F FI + + A +VG+ L + LTG L + Q A+ E M S ER+ +Y + EA +D D WP G I+ N+ ++Y EG VLKG+ K+KEKIGIVGRTGAGKSS+++ALFRL E + G I +DG NI + GL +LR ++IIPQDP++F G+LR+NLDPFNE + ++ +++ + ++S+ G++++++E G N S GQRQL+ LARA+LR KIL+LDEATA+VD ++D IQ TIR +F++CT+LTIAHRL+T+MDSDRI+V+ G+++EF P+ LLQ+++ +L+ LV G + LR++ A+++ + N+ D E + +N
Sbjct: 27 KKSPEENSNFLSNLTFSWADGFVIHCFRNVLQLSHLWDLASYDKSEYLAKKIAKSW----EIEIQKPKPSYLRAGFRAFG-KLQLLSIFLYAISVGIQFVGPEILGRMVTFVVESKLGTSTEDPNMGYYYALIMFGTAMIGSFCTYHANRISF---RTGDRLRSIIVLDVYKKAIKLSNSARSDTSPGQIVNLMSNDAQRMVEVFGMFNNGALALP-QIIICLALLYKKIGWPTFVGLGLMLAAIPFNGMAAKKLTETRKYLVSLSDSRVKATNEILQAIKIIKLYAWEDSFAKKVIEHRNNEIKLLFSYSRYRTILIVIISALPTAAAILVISSYYGHEKSLDASRIFSALSYLNLLRLPLG-FLPIIIALGIQMQIAGKRVTDFLLLPEMKDIQ-----QIDNPSL--PNGVYMKNSTTTWNKLKEDSFGLKNINFEATGTSLTMVVGSVGSGKSTLVQAMLGELEIIDGEIGIKGSIAYVPQQAWIINATLKENIIFGKELDEERYQKVLEVCALKRDIELFPQGDSVEIGERGINLSGGQKQRVSIARAVYSDADVYILDDPLSAVDSHVGKHLFHKCFKGILSSKTVILVANQLNYLPFADNTVVLKSGEIVERGTYYELINSKLEFSSIL-EKYGVDENVIS--------------------------KKDDIDEDEDEDQDTIEKVEIDLNKDEKS-------QPKSKSSNTDGTLISEEESEQGAVAGKVYWKYVTAGGGLLFLVSMIFFLLET-GSKTFSDWWLSHWQTESSERM--------ESILLGEEPT----GLTDDQNLGIYIGLGMAAVFISVCKNFIYYEYSVYASRAIHHELFNALLKKPMYFFDQTPIGRIINRFTRDLDGIDNLIATSISTFLTLMLTVIATIILVSIIVPFLLIPLAPISIIFFFLQYFYRYTSRGLQRIEAITRSPIFNHFSETLNGVVSIRAYKKQQENILINQ-KRLDD-NNNCYLTLQAMNRWLGLRLDFLANL-ITFFACIFITIDKDTISPA---------NVGLALGYALSLTGNLNYAALQAADTETKMNSVERISQYIRGAVEAPQIID---DCRPSPDWPINGSIKFDNLVMRYREGLDPVLKGITCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASEGSISIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENLDPFNERSEEDLFSTIEDIQMSAVVKSLEGGLDSKVTENGENFSVGQRQLIVLARALLRKPKILVLDEATASVDGQSDSLIQATIRNKFSNCTILTIAHRLNTIMDSDRIMVLDAGKISEFDEPWTLLQNQNGLLTWLVDETGPQNAIYLRKLAEAKKNGIDINEIMPIDNETTPKDNIN 1327
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|75071939|sp|Q6UR05.1|MRP1_CANFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 781.941 bits (2018), Expect = 0.000e+0 Identity = 465/1364 (34.09%), Postives = 735/1364 (53.89%), Query Frame = 0
Query: 13 PRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKS-------------------------------------EPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVL--SNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCI--QTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQ----SGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDR 1330
P +ASFLS FWW+ L+ GY++ LE DL+ + D SE + L ++W + R+ EPSL + + KTFG F +F + + A P L +++ + YLY + + + L T H YF GMR++ + +YRKAL +++++ STVG++VNL++ D RF +I+ +W+ PLQ+IL + L W +G S LAG ++I VPL + + ++ K D RI++M+EI+NGIKV+K+YAWEL F V R++E+ V++++AY + + ++ L+ +V N +++A+K F++LAL+N +R + + +P I+ + +A VS+KR++ FL E + S R + S+++K T TW TL + G +VA+VG VG GK+S+L ALL E+ +G + I+G ++Y Q+ W+ + S+R NILFG E+ Y +E AL D+ GDRT +GE+GV LSGGQK RVSLARA+Y D+DIYL DDPLSAVDA VGK+++E I + LK K +LVTH I YL D+I+V+ G I G+Y ELL+ F+EF+ + D + D + L + +P V + + + +++ + + S +S S AE ++ PK ++ + + A G V L YW Y ++ + L++ + L + WL +WT+ P + K L ++G + ++ I ++ + +S LH D+ + ++R+P FF+ P G ++NRFSK++ ++D ++P V+ + +++G +I+ PI + +++ ++++Y++SSR +KR E +++SP++S +L G++ IRA++ + I + D D + A+Y + RW + L+ CVG I + A+FSV S+ +G VG+ ++ + +T L W +R ++EME + + ER+ EY + E EA ++ +M P +WP+ G +E R+ L+Y E VLK ++ EK+GIVGRTGAGKSSL + LFR+ E GEI++D +NI +IGLH+LR +I+IIPQDP++F GSLR NLDPF++Y D ++W +L+ AHL + +P + E +EGG NLS GQRQLVCLARA+LR KIL+LDEATA VD TD IQ TIR +F DCTVLTIAHRL+T+MD R++V+ G + E P DLLQ R
Sbjct: 209 PESSASFLSRVTFWWITGLMVRGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQRKITYSSKDPAKPKGGSQVDVNEEAEVLIVKTPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDL-MMFAGPEILKLLINFV--NDKKAPDWQGYLYTALLFICACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNI-LPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGAN---SITVKNATFTWARS--DPPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRLLVTHSISYLPQVDVIIVMTGGKISEMGSYQELLARDGAFAEFLRTYASGDQEQAEQD-DGLTGVSSPGKE--VKQMENGMLVTDVAGKQLQRQLSNSSSYSGDVSRHHTSTAELQKAGPK---NEDAWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLF-LCNHVASLVSNYWLSLWTDD---------------------PIVNGTQEHTKIRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHVDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIASIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLE---------CVGNCIVL-----FAALFSVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ---EMAPPSTWPQVGRVEFRDYGLRYRENLDLVLKHINITINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRVKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGQPSDLLQQR 1518
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|6920069|sp|O15438.3|MRP3_HUMAN (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multi-specific organic anion transporter D; Short=MOAT-D; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 771.541 bits (1991), Expect = 0.000e+0 Identity = 472/1380 (34.20%), Postives = 735/1380 (53.26%), Query Frame = 0
Query: 13 PRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQV------------------EDET------RKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFN-FSFFFTSTKVILLAILI-PFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH--LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGD----LEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIH--------------------TESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSA----WYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQS----GDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVD-HHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDR 1330
P +A FLS FFWW + GY+ LE DL+ D S+++ +L W Q EDE R +PS L+A++ TFG F F ++ + P LS + + + +L + L S + + Y+ + G++ R + +IYRKAL ++++ STVG++VNL++ D RF F++ LW+ PLQ+IL + W+ +G S LAG ++ +PL + +++ K D RI++MSEI+NGIKV+K+YAWE F K V+ R+ E+ ++R AY F++ + V L+ + + +V N V++AEK F++++L+N +RL + + +P I+ +++A VS+KRIQ FL E D S E + +++I T TW TL +L +Q G +VA+VGPVG GK+S++ ALLGE+ +G+++++G ++Y Q+ W+ + +++ N+LFG+ K+Y +TLE AL D+ GD+T +GE+G+ LSGGQ+ RVSLARA+Y DADI+LLDDPLSAVD+ V K++++ I L K +LVTH I +L D I+VL G + G Y LL F+ F+ + ++D D LE D + L + S V + M + A+S DG+ GQ VP+ H E AA+G+V L +W Y ++ LA+ +L + +VWL WTN ++ Q NT++ L ++ + + + ++ + ++ LH + IR+P FFD P GR+LN FSKD+ +DE+L PV+ +++ F + + + VI+ P+ +AVL+ +++++Y ++SR +KR E +++SPI+S + ++ G + IRAY +F+ I D A Y ++ + RW + ++ ++G CV F A+F+V +S G VG+ ++ + +T L W +R +++E+ + + ERV EY K E+EA V+ P PE WP G +E RN ++Y G VL+ + EK+GIVGRTGAGKSS+ + LFR+ E GEI +DG+N+ +IGLH+LR Q++IIPQDP++F G+LR NLDPF Y + IW AL+ +HL + S P G++ + SEGG NLS GQRQLVCLARA+LR ++IL+LDEATA +D TD IQ TIR +F CTVLTIAHRL+T+MD R+LV+ G VAEF SP +L+ R
Sbjct: 208 PETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDL-LSFINPQLLSILIRFIS--NPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNM-LPQLISNLTQASVSLKRIQQFLSQEELDPQSV------ERKTISPGYAITIHSGTFTWAQDL--PPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYAPDEDQGHLEDSWTALEGAED----KEALLIEDTLSNHTDLTDNDPVTYVVQKQFMRQLSALSSDGE-------------GQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWDYAKA-VGLCTTLAICLLYVGQSAAAIGANVWLSAWTN--DAMADSRQNNTSL-------------------RLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSR----DFEIISDTKVDANQRSCYPYIISNRWLSIGVE-----FVGNCVVLF---------AALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRP----PEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIAAR 1514
BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Match: gi|85701143|sp|Q8CG09.2|MRP1_RAT (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 770.385 bits (1988), Expect = 0.000e+0 Identity = 466/1378 (33.82%), Postives = 746/1378 (54.14%), Query Frame = 0
Query: 13 PRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQ--------------------------------------VEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQ--VINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGES-TLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTH--LKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEH--TEED----DDAIAG------DLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQ----SGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPT-GEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDR 1330
P +ASFLS FWW+ ++ GY++ L+ +DL+ + D SE + L +W + V+ + +PSL + + KTFG F ++ + + A P L +++ + YLY + + + L T H YF GMR++ + +YRKAL +++++ STVG++VNL++ D RF +I+ +W+ PLQ+ L + W +G S LAG ++I VP + + ++ K D RI++M+EI+NGIKV+K+YAWEL F V + R++E+ V++++AY + + ++ L+ FV ++ +++A+K F++LAL+N +R + + +P I+ + +A VS+KR++ FL E + S + M S+++K T TW A+ E TL + G +VA+VG VG GK+S+L ALL E+ +G + ++G ++Y Q+ W+ + S+R NILFG E Y +E AL D+ GD T +GE+GV LSGGQK RVSLARA+Y ++DIYLLDDPLSAVDA VGK+++EK + LK K ILVTH I YL D+I+V+ G I G+Y ELL F+EF+ + TE+D DD+ G + + + + + +D + P + RH S S S S+++ ++ S AE +S KE + + + A G V L YW+Y ++ + L++ + L + WL +WT D+ P + + L ++G + + + ++ + +S LH D+ + ++R+P FF+ P G ++NRFSK++ ++D ++P V+ + S++G V +I+ PI + +++ ++++Y++SSR +KR E +++SP++S +L G++ IRA++ + I + D D + A+Y + RW + L+ CVG I + A+F+V S+ +G VG+ ++ + +T L W +R ++EME + + ER+ EY + E EA ++ + P +WP G +E R+ L+Y E VLK ++ + EK+GIVGRTGAGKSSL + LFR+ E GEI++DG+NI +IGLH LR +I+IIPQDP++F GSLR NLDPF++Y D ++W AL+ AHL + ++P + E +EGG NLS GQRQLVCLARA+LR KIL+LDEATA VD TD IQ TIR +F D TVLTIAHRL+T+MD R++V+ G + E +P +LLQ R
Sbjct: 209 PESSASFLSRITFWWITGMMVQGYRQPLKSSDLWSLNKEDTSEEVVPVLVNNWKKECVKSRKQPVRIVYAPPKDPTKPKGSSQLDVNEEVEALIVKSSHKDRDPSLFKVLYKTFGPYFLMSFLYKALHDL-MMFAGPEILELIINFV--NDREAPDWQGYLYTALLFVSACLQTLALHQYFHICFVTGMRIKTAVVGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNI-LPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMN---SITVKNATFTW---ARDEPPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFVRTYANTEQDLASEDDSKNGVSGLGKESKPVENGILVTDAVGKPLQ---------RHLSNS-SSHSVVT-----NQQHSSTAELQKSGVKE----ETWKLMEADKAQTGQVKLSVYWNYMKAIGLCISFLSIFLF-LCNHVSALASNYWLSLWT--------------------DDRPAVNGTQENRNFRLSVYGALGILQGVAVFGYSMAVSIGGIFASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLE---------CVGNCIVL-----FAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEASWQIQ---ETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQR 1519
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|586962528|gb|AHK05652.1| (ATP-binding cassette transporter sub-family C member 4 [Tigriopus japonicus]) HSP 1 Score: 1992.62 bits (5161), Expect = 0.000e+0 Identity = 982/1403 (69.99%), Postives = 1163/1403 (82.89%), Query Frame = 0
Query: 1 MDADDVIIQRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETR---KSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELG-QANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQNKPFMEDEEYAE-------AEEMNLQVTVEDDEKFITKL 1392
MDA++ Q+ NPRENA+ LSIAFFWWLNPL+ LGYKKNLE+ DL+R L++D S LN+++++HW +++ + + K +PSL RAVI+TF GEF FLG+FTFFEEC IRIAQP+FLSWFV+YF PGQ ++ R EAY+YG VVLMSALYTFTHHPYFFGVM+VGMRVRITLSAL+YRKAL+LSSA++G+STVGQMVNLLANDV+RFD ACLFIHYLWAGPLQL++VV LTW E+G ST+AGAGI++ SVPLQSWIGR+FS+LRLETAKKTD RIRIM+EIINGIKVIKMYAWE F K+++ RE EMDVIRRTAYFRGFNFSFFF ++KVILLAILIP+VL+ Q+INAEKVFLTL+LYNTVRLSMTLFVP+ I+M SE LVSI RIQ FL+M ERD T +H+ES E PIS+ I GLTA+W A + TL N+ A+AG++VAIVG VGSGKTS+LQA+LGEIP+ +G+INI+GR+SYAAQEPWVFSGSVRHNILFGE + EK+Y+KTLEV ALEHD+ QWEFGD+T+VGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDA VGKYL+E CIQ+HLK KLVILVTHQIQ+LKDAD+I+VLKKGSI+GRGTY EL S GTDF+EFI E E+ ++ + L D PS R S + R R YS+G +SIMS++ +SED + E+D+ +E + PK+ ES LG+VSL YWSYFR+GA LVL+ VL LN+ Q +FT DVWLGIWTNQEE +M ++ + S+ + + TME+I+ SN NL IFG MTL+LV+ SL+RTI F L+CK++S LH+ MFK+IIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPV DVI+IFL++ GIV VIV+YQPIVF PTCIMAVLF LRK+YLSSSRAIKR+EG+AKSPIFSQLAS+LGGLTSIRAY+AE IL+ EFDRIQD+HTSAWYSFLATTRWFGLWLDWLVV+YL CV +F+FM +GSS QSGDVGVVL+SCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKI+SEA+LK DH P + E+WP GV+EC +V LQYGEGEK VLKGV+F+TK +EK+GIVGRTGAGKSSLI ALFRLTEPTG+I++DGVNIQ++GLH LR +ISIIPQDPLVF GSLRKNLDPF++YQD QIWQAL++ HLDQA++ M G+ETEMSEGGSNLSAGQRQL+CLARAIL++NKIL+LDEATANVDPRTD IQETIR RFADCTVLTIAHRLHTVMDSDRILVMSDG+VAEF++PY+LLQD SVLSELV+NV ++QL+LRRIARE+F+RQ + + + E +Q+ VEDDEK +TKL
Sbjct: 1 MDAEEAFQQKPNPRENANILSIAFFWWLNPLMWLGYKKNLEIQDLYRALKIDQSADLNSRIEKHWQRELDKQAQSNNKHKPSLFRAVIRTFYGEFCFLGLFTFFEECLIRIAQPVFLSWFVAYFTPGQTAISRTEAYIYGFAVVLMSALYTFTHHPYFFGVMKVGMRVRITLSALVYRKALKLSSAALGQSTVGQMVNLLANDVNRFDGACLFIHYLWAGPLQLLIVVYLTWNEMGVSTMAGAGIILISVPLQSWIGRMFSKLRLETAKKTDTRIRIMNEIINGIKVIKMYAWEFSFMKLIESARESEMDVIRRTAYFRGFNFSFFFVASKVILLAILIPYVLTGQIINAEKVFLTLSLYNTVRLSMTLFVPFAISMGSEGLVSIGRIQKFLMMEERDKTC-LACVHEESSSKEKPISLDICGLTASWT-DATADPTLNNVSFSARAGEIVAIVGTVGSGKTSMLQAVLGEIPSKEGKINIRGRVSYAAQEPWVFSGSVRHNILFGENYDEKRYMKTLEVCALEHDLEQWEFGDKTLVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAHVGKYLFENCIQSHLKSKLVILVTHQIQFLKDADMILVLKKGSIQGRGTYAELESLGTDFTEFISETKEDQENEEEEEDATLIDGEIPSPK--EHRSLSIRSCLQRRSRGYSLGGDSIMSMISGVSED---ILEYDQVMAEENNTEEKKKPKVEAESVVLGAVSLAAYWSYFRAGAGVLVLICVLSLNIGVQVIFTGADVWLGIWTNQEEQEMQQSSISANNSTNTTKIFTMEDISQSNTNNLYIFGAMTLSLVVASLIRTIQFLLVCKNASTQLHHSMFKRIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVFLDVITIFLTMAGIVSVIVWYQPIVFLPTCIMAVLFTFLRKFYLSSSRAIKRAEGVAKSPIFSQLASTLGGLTSIRAYRAEHILVKEFDRIQDVHTSAWYSFLATTRWFGLWLDWLVVVYLACCVCSFLFM-NGSS---------QSGDVGVVLSSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIQSEAELKTDHPPPGYDEEAWPGTGVLECNDVCLQYGEGEKMVLKGVNFLTKPREKVGIVGRTGAGKSSLIGALFRLTEPTGQIILDGVNIQQLGLHALRKKISIIPQDPLVFTGSLRKNLDPFDDYQDHQIWQALEQVHLDQAVKHMSHGLETEMSEGGSNLSAGQRQLICLARAILKHNKILVLDEATANVDPRTDMLIQETIRTRFADCTVLTIAHRLHTVMDSDRILVMSDGKVAEFNTPYELLQDPRSVLSELVANVSLASQLKLRRIAREAFVRQKNLDLAEPKITNNIRNNSFVENSKVQIMVEDDEKIVTKL 1386
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|1325299980|ref|XP_023331773.1| (multidrug resistance-associated protein 4-like [Eurytemora affinis]) HSP 1 Score: 1427.92 bits (3695), Expect = 0.000e+0 Identity = 718/1435 (50.03%), Postives = 978/1435 (68.15%), Query Frame = 0
Query: 2 DADDVIIQRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKSE------PSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIP-----------------------------EHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQ---------ANTTM-----SSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKV-DHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQNKPFMEDEEYAEAEEMNLQVTVEDDE 1386
D + V+ Q +NPRE A+ S+AFFWWLNPLL LGYKK+L++ D+F L+ DGS+ L +LQR WD +++ K E PSLL+A+++ FG + FLG+FTF EEC +RI QPLF+ W + YF+PG N + EAY YG GV+ MS LYTFTHHPYFFGVM GMR+RI L+YRKAL+LS++++GK+TVGQMVNLL+NDV+RFD+A L+ HYLWAGPLQL+++ L W+ VG S+LAG +++ VP+Q+W+G+ F++ R+ TA TD R+R+M+EI+NG+KVIKMY WE PFTK+ ++ R+ E+DVIR T+Y+R FNFSFF+T+++ ILL+ + + + +++ +EK F+ L+LYNTVRLSMTL+ P I+ + EA VS+ RI+DFLLM ER + IH + + +SV I G++ W+ + + E+TL + L+ + GQ+VA++GPVGSGK+S+LQA+LGE+P G I+I G +S++ QEPWVFSGSV NILFG+ + + +YL ++ ALEHD+ QW GD+T+VGE+GVALSGGQKARV+LARA+YR AD YLLDDPLSAVDA VGK+L++KCIQ +L+ VILVTHQ+QYLKDADLIVVLK+G ++ GT+ L +G DFS + H + D HL +P+ S R R+ SVGS+ M +S K + S P E + G+V G Y SYF+SG + ++ +L++NL QGL++ D+W+ WT+ EE +++ Q +NTT+ S +E + S+ NL I+ + ALVI S++RT+HFF++C +SV LH MF ++++A RFFD+NPVGR+LNRFSKD+GS+DE LPP D +IFL+ILGI+ VI +P V PT ++ ++F++LR++Y+ S+R IKR EGIA+SP+FS L++SL GLTSIR + AE +L EFDR+QDIHTSAW++F++ TRWFG+WLDW+V++YL V +F+ + GDVG+ ++SCI LTGMLQWG+RQ+AE+ENLMTS ERV+EY ++E EA + + P P+SWP GVIE ++V+L+Y E E VLKG+DF T + EKIGIVGRTGAGKSS+I ALFR+ EPTG I +DGV++ +IGL +LR ISIIPQDPL+F GSLR+NLDPFNE+ D IW+ LKE ++ + + + GIETEMSEGG+N S GQRQLVCLARA LR+N+IL+LDEATANVDPRTD IQE IR RF +CTVLTIAHRL+T+MDSDRILV+ DG+V EF +PY+LL+ VL EL G +L+ IA S ++ ED NL V E
Sbjct: 8 DTEQVLKQPKNPREKANIFSVAFFWWLNPLLGLGYKKDLDIEDIFENLKSDGSDELGERLQREWDKELKKADYKKEKGEEYTPSLLKALLRQFGPFYAFLGIFTFIEECLLRIFQPLFMGWMMQYFSPGSN-MSLEEAYFYGAGVIAMSVLYTFTHHPYFFGVMHTGMRIRIAACCLVYRKALKLSNSALGKTTVGQMVNLLSNDVNRFDTAVLYSHYLWAGPLQLLIITVLLWQRVGVSSLAGTLLLLLFVPVQTWVGKKFAQFRVMTAACTDKRVRLMNEIVNGMKVIKMYTWEQPFTKMAEEARKAEIDVIRHTSYYRAFNFSFFYTASRFILLSTFLVYGFTGEILTSEKAFICLSLYNTVRLSMTLYFPSSISSLGEAKVSVSRIRDFLLMEERGTEETSRAIH----ALNSKVSVEISGVSGKWN-KDETENTLSKVYLKIRPGQLVAVIGPVGSGKSSLLQAILGELPITCGGIDIHGEISFSPQEPWVFSGSVEDNILFGKPYNKSRYLSVIKACALEHDLTQWSHGDKTLVGEKGVALSGGQKARVTLARAVYRVADCYLLDDPLSAVDAHVGKHLFQKCIQGYLRDSAVILVTHQLQYLKDADLIVVLKEGKVQETGTFEHLAKNGLDFSSLLTLEEEEEKEEEEDIFSEEDIILMKGRDPGWNHLNKSDQFTKDSRIHLEHEKPDFKNFDMPKTLS-------RARTLSVGSD-----MSKISNQRKEI---------------SSPVASKEEKSAGAVKGGLYISYFKSGGNCCTVIFILLVNLLCQGLYSGSDIWISYWTSIEEKELFIEQIEELPAPILSNTTLPRINISMNYEEAWSNPNNYNSHYLNLGIYAALVGALVIASMIRTVHFFVVCMRASVYLHNSMFLRVVQAQCRFFDVNPVGRILNRFSKDVGSMDESLPPAFIDAFTIFLNILGIMAVIFSVRPWVILPTLLLVIIFILLRRFYMRSARDIKRIEGIARSPVFSHLSTSLNGLTSIRVFNAEDMLRKEFDRLQDIHTSAWFAFISGTRWFGVWLDWIVIIYLASVVFSFL----------ILGGDLVGGDVGLAISSCITLTGMLQWGVRQSAEVENLMTSVERVMEYSRLEQEAPATIMETKP----PKSWPSRGVIEFKDVKLRYAETEPLVLKGLDFKTHNAEKIGIVGRTGAGKSSIITALFRMAEPTGSIYIDGVDVLKIGLKDLRSTISIIPQDPLLFTGSLRRNLDPFNEFSDDMIWKVLKEVNMSEPVSELKNGIETEMSEGGTNFSLGQRQLVCLARASLRHNRILVLDEATANVDPRTDKLIQEQIRTRFRECTVLTIAHRLNTIMDSDRILVLGDGKVVEFDTPYNLLRKEGGVLVELAEQTGEENLRKLKEIAAISNMKDYSDIGEDNVTEVDHNTNLDEDVSSPE 1395
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|675382726|gb|KFM75623.1| (hypothetical protein X975_25121, partial [Stegodyphus mimosarum]) HSP 1 Score: 1249.96 bits (3233), Expect = 0.000e+0 Identity = 629/1392 (45.19%), Postives = 907/1392 (65.16%), Query Frame = 0
Query: 9 QRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQ-VINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESP--PMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVG-SESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQ--MYEAQANT-------------------------TMSSASDET-----PTMEEINASNKR-----NLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLR 1359
+ NP A+F S FFWWL PL G K NL+L+D++ VD SE + K+QR W+ ++ +PSL++A I++FG + G FT EEC I + QP+ L + + +FA V + + Y Y V L++A++ FTHH YFFG R+GMR+RI L+YRKAL+LS A++ ++TVGQMVNLL+NDV+RFD + +++ YL AGP+Q +++ + W +G+++LAG +++ +P Q +G++FS+LRL+TA TD RIR+M+EII+G++VIKMY WE+PF +V +R KE+ IRRTA RG N + FF S+KVILL + FVL + + EKVF+ ++L+N +R++MTLF PY IA +E+++S+KRIQ FLL+ E+ T+ + D S P + ++ + A+W+ GESTLKN+ L K G+++A+VGPVG GKTS+L ++LGE+P GE+ ++G+++YA+QEPWVF GSV+ N++FG TF E +Y L V AL+ DI Q+ +GD+T VGERGV+LSGGQKARV+LARA+Y DADI+LLDDPLSAVD+ V K+L+EKCI +LK K+ IL THQIQ+LK A I+VLK+G GTY +L+ +G D + ++ +E +A + S SV E+ + + ES +S+ ++ ED +DE + +++ + PK E + GSV Y Y +SGA L +LI +ATQ LF D WL WTNQE+ + + + AN T+++ SD+ +E++ + ++ NL ++ G+ L + ++SLVRT FF MC +S+ LH MF+ ++R+P FFD NPVG +LNR S+D+G ID++LPP +D I IF ++ GI+ V+ +P + PT I++ +FV LR++YL ++R +KR EGI +SP+FS L++SL GLT+IRA+K + FD QD HT+ W+ F++ TRWFG+ LDWL VLY+ + + + + S+ + G+ + S + L+G QWG+RQ+AE+E+ MTS ERV+EY + SEA L + D P+ WP +G + NV L+Y E VLK ++F +EKIGIVGRTGAGKSS+I LFR+TEP GE+ +DG+ ++IGLH+LR +ISIIPQDP++F G +R+NLDPF E+ D ++WQAL+EA+L +AI MP G++TE+SEGG N S GQRQL+CLARAILR N+IL+LDEATANVDP TD IQETIR RFA CTVLTIAHRLHT+MDSDR+LV+ G V EF PY+LLQ+R+S+ S +V G +LR +AR + L+
Sbjct: 8 ENPNPWTKANFFSRIFFWWLTPLFLKGKKGNLKLSDIYDCPTVDSSEKIGEKMQREWEKELRKLKDGKQPSLVKATIRSFGLYYCLNGFFTLIEECFIHVMQPILLGYLIEHFAR-MKVVTKQDLYFYTACVCLLAAMFVFTHHRYFFGAQRIGMRLRIACCTLVYRKALKLSQAALSRTTVGQMVNLLSNDVNRFDQSVVYLPYLVAGPIQTAIIIGVLWYHIGYASLAGISVLLLYIPFQGLMGKLFSKLRLKTAVLTDERIRLMNEIISGMRVIKMYGWEIPFANLVDLSRRKEVKKIRRTAILRGVNLAMFFISSKVILLISFVVFVLGVKGDLTPEKVFVCMSLFNNLRVAMTLFFPYAIAQGAESIISLKRIQKFLLLEEQQETA----LLDVSNLRPKLNQCGIWMQKVVASWNKD--GESTLKNVTLTVKPGELLAVVGPVGCGKTSLLMSILGELPIVSGEVKVRGKVAYASQEPWVFGGSVKQNVVFGSTFDENRYKTVLNVCALDKDIEQFPYGDQTAVGERGVSLSGGQKARVNLARAMYFDADIFLLDDPLSAVDSSVSKHLFEKCINGYLKDKVRILATHQIQFLKGASQILVLKEGRCLALGTYDQLIEAGVDLGSLMEDYEQERRQRLASMTSTTS---------------SISVVDELTDGTTPIPMYESTLSISSSVGED------YDEIEGEKM--KDKAPKATEEIKSTGSVKFKVYKEYVKSGAGLFHRLLLLISYIATQALFNGSDFWLTAWTNQEQRKYNIKDCWANANKTFLNETGYYNDTYGVLDRDLFRLTIANVSDDCFELTQNYLEDLKEATEKVDMHKNLYVYAGLVLTVFLLSLVRTTSFFQMCMKASITLHNKMFRSVLRSPVSFFDSNPVGNILNRASRDLGLIDDVLPPTASDFIEIFCNLFGIICVVAIVEPWLLLPTFIISTMFVFLRRFYLPTARDVKRYEGITRSPVFSHLSTSLYGLTTIRAFKVQQSFEVSFDHYQDRHTATWFMFISVTRWFGIVLDWLCVLYITSVTVSMVVLSEDPSY---------ASKAGLAIASALQLSGSFQWGVRQSAEVESQMTSVERVIEYSNLGSEAAL--ESEKDKKPPKDWPSKGYVVYHNVNLKYSPNEPPVLKNLNFEIYPEEKIGIVGRTGAGKSSMIATLFRMTEPEGEVKIDGICTKDIGLHDLRKKISIIPQDPVLFTGPVRRNLDPFGEHTDDELWQALEEAYLKEAIEEMPGGLDTEVSEGGGNFSVGQRQLICLARAILRRNRILVLDEATANVDPNTDSLIQETIRDRFAHCTVLTIAHRLHTIMDSDRVLVLDAGEVKEFDEPYNLLQNRNSLFSHMVQMTGPGMAQQLREVARVAHLK 1358
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|1316172635|ref|XP_023231775.1| (multidrug resistance-associated protein 4-like [Centruroides sculpturatus]) HSP 1 Score: 1238.79 bits (3204), Expect = 0.000e+0 Identity = 627/1370 (45.77%), Postives = 902/1370 (65.84%), Query Frame = 0
Query: 8 IQRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDA---TSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDET-PTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYL-GFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFL---RQNKPFMEDEE 1369
+ + NP E+AS + F+ WL PL GYK LE+NDL+R + D SE L ++LQ+ WD E +K PSLL+AVI+TFG + EEC IR+ QP L V Y+A +N +++YL G+ L++ + FTHH YFFG R+GMR+RI ++IYRKAL+LS S+GK+TVGQMVNLL+NDV+RFD +++ +L AGPLQ +++ + WR +G++T AG +++ +P Q +G++FS+LR +TAK TD RIR+M+EI+ G++VIKMY WE F ++V R KE+ IR+T+ RG N + FF S+K+IL + ++L + A VF++++L+N +RL MTLF PYGI+ +EAL+S+KR+Q FLL+ E++ T S+ R P + + +TA+W+ GE+TL+ + L + G+++A++GPVGSGKTS+L ++LGE+P+ GEI ++GR++YA+QE WVF GSV+ NILFG F E+KY L VSALE DI + +GDRT+VGERGV+LSGGQKARV+LARA+Y DADI++LDDPLSAVDA V K+++EKCI +LK K+ IL THQIQ+LK A I+VLK+G GTY EL+++G D + E+ E R + T V + M+ S +++EF E +P +G S PK E+ G+V + Y SY ++G+ + + +L+ +ATQ LF D WL WT++E+ + E Q + ++ T TM I N+ ++ G+ L ++SLVRTI FF MC +S+ LH +MF IIRAP FFD NPVG VLNRFS+DMG ID++L D+ISIF ++ GI+ ++ + PT ++A++F+ +R+++++++R IKR EGI +SP+FS L +SL GL +IRA++ + FD+ QD HTSAW+ FLA TRWFG+ LDWL VLY+ VG + G S+G G++G+ ++S + L+G QWG+RQ+AE+E+ MTS ERVLEY ++ SEA L+ PD P WP +G+I +V LQY E + VLK +++ K +EK+GIVGRTGAGKSS+I LFR+TEPTG + +D + EIGLHELR++ISIIPQDP++F G +R+N+DPF+E+ D +W+ L++ HL A++ + G++ E+SEGGSN S GQRQL+CLARAILR NKIL+LDEATANVDP+TD IQETIR++FA CTVLTIAHRLHT+MDSDR+LV+ GR+ EF PY+LL+++ + +V G + +L IA++++ R+NK + D+E
Sbjct: 6 LPKVNPYESASVFARMFYCWLYPLFLKGYKTELEVNDLYRNPKTDCSEKLGDRLQKQWDK----ELKKKHPSLLKAVIRTFGCLYFLHASLILVEECIIRVCQPYLLGVIVDYYA-NKNKEKELDSYLSAGGICLLAVCFVFTHHVYFFGAQRIGMRIRIACCSIIYRKALKLSHTSLGKTTVGQMVNLLSNDVNRFDYCIIYLPHLIAGPLQTAIMLLVLWRYLGYATFAGLSVLLLYIPFQGGMGKLFSKLRSKTAKLTDERIRLMNEIVAGMRVIKMYTWEFAFAELVDKARRKEIKKIRQTSILRGINIALFFVSSKLILFLSFLTYILLGGQLTARTVFVSISLFNNLRLCMTLFFPYGISQGAEALISLKRLQRFLLLEEQEENEMTVSNLR------PKLNQCGIWMNKVTASWNKD--GEATLQRITLNVQPGELLAVIGPVGSGKTSLLMSMLGELPSSSGEIKVKGRIAYASQEAWVFGGSVKQNILFGNVFDEEKYNNVLHVSALEKDINLFPYGDRTLVGERGVSLSGGQKARVNLARALYLDADIFILDDPLSAVDAAVAKHIFEKCIMQYLKNKVRILATHQIQFLKKATKIIVLKEGKCLALGTYEELVTAGIDVGSLVEENEET--------------------------RSRKNTTGSFSSADEDVIISNPQPAMLYESNSSLAMSEF-EGEPVRVGDDKS-PKQQQETKTAGAVGVAVYKSYIKAGSGPFLQILLLLSYIATQTLFNGSDYWLSKWTDEEQLYIKEKQIFDNHTKYNNNTNDTMNIILPPRNFNMYVYSGLIWGLFLLSLVRTIAFFTMCMKASIKLHNNMFNCIIRAPIAFFDNNPVGEVLNRFSRDMGFIDDVLDITADDMISIFCNMFGILVLVAIINYYLIAPTIVLAIMFIFIRRFFIATARDIKRLEGITRSPVFSHLTTSLYGLATIRAFRCQRTFEIAFDKYQDRHTSAWFLFLAVTRWFGIHLDWLCVLYIVTVTVGLILAPG--------LSLG---GEIGLAISSALALSGSFQWGVRQSAEVESQMTSVERVLEYSRLPSEAALR--SSPDKRPPPDWPNKGMITFDDVSLQYLENDPPVLKNLNWHVKPQEKVGIVGRTGAGKSSMIATLFRMTEPTGTVYIDNIATSEIGLHELRNKISIIPQDPVLFTGPVRRNIDPFSEHIDETLWKVLEDVHLKDAVQELQGGLDAELSEGGSNFSVGQRQLICLARAILRQNKILVLDEATANVDPKTDSLIQETIREKFASCTVLTIAHRLHTIMDSDRVLVLDAGRIQEFDEPYELLKNKSGLFYNMVQMTGAAMSRQLYEIAKQAYYFHKRRNK--ISDKE 1319
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|1215273652|gb|OXA59962.1| (Multidrug resistance-associated protein 4 [Folsomia candida]) HSP 1 Score: 1191.41 bits (3081), Expect = 0.000e+0 Identity = 610/1355 (45.02%), Postives = 874/1355 (64.50%), Query Frame = 0
Query: 12 NPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQV---EDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFI--PEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLM-MAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQ 1360
+P A+ +S FFWWLN G KK L+L DL++ L D S+ L +++++ W +V E+ + +PSL R +IK FG + +GM F EEC IRIAQP+ L + F+P + S + E +L GVVL SA+YTFTHHPYFFGV VGM++RI +LIYRKALRLS A++GKST+G+M NL++NDVSRFD + +F+HYLW GP+Q +V + W G + LAG I++ VP Q ++G+ FS LR TA KTD RIR+M+EI+ G++ IKMYAWE PF+ +V ++R+ E+ VI++T R N S F+TS+K+I+ LI +VL+ + A KVF+T ALYN VRL MTLF P G++ + E LVSI+RI++FLLM ER +S + ++ A W + ++TL N+ L ++ AIVG VGSGKTS+LQ++LGE+P G+I G L Y +QEPWVFSGSVR NILFG + +++Y + +E AL D+ D ++VGE+G +LSGGQKAR++LARA+Y +ADIYLLDDPLSAVDA+VG++++++CI LK K ILVTHQ+ L+ + IV+L+ G I +G Y ++ S T S + P +A + + + +A S + F + +YS+ E + +D K+ + D P + +S+PK++ E +A G V+LG Y YF+SG++ L ++ N+ATQ L+ D WL WT +E + ++ +S P + I + I+ G+ L SL+RT+ FF +C +SVNLH MF ++RAP +FF+ NP+GR+L+R SKD+G ID++LPP + D + IFL+++GI+ ++ + P ++ V+F LRK+YL ++R++KR EGI +SP+FS L++SL GL++IRA+K ES I +FD QD+HTS+WY FLA +RWFG+WLDW+ V ++ F +F+F D + ++G+ ++S + LTGM QWG+RQ+AE+EN M S ERV+EY ++E EA L+ P WP G I +V+L+YG E+ VLK + V K EKIGIVGRTGAGKSSLI ALFR+ EPTG IL+DG++I +GL LR ISIIPQDP++F G+LR NLDPFN ++D+++W L++ HL ++ + G++ E+SEGG+N S GQRQLVCLARAIL+NNKIL+LDEAT+N+D TD IQ TIR +FA+CTVL++AHRLHTVMD D+ILV+ G + EF PY LLQ+ S L L G +L I++E+ L++
Sbjct: 12 SPYLKANIISKLFFWWLNAFFGKGNKKALDLGDLYQALPNDRSKFLGDRIEQLWKEEVKRCEEGKKPRKPSLRRVIIKQFGAYYMMVGMLAFLEECFIRIAQPICLGLLLHSFSP-EYSASKTEKWLSAAGVVLGSAMYTFTHHPYFFGVQYVGMKIRIACCSLIYRKALRLSQAALGKSTIGEMTNLISNDVSRFDQSTIFLHYLWIGPIQTAIVTGILWHFYGVACLAGLSILVLFVPFQGYMGKRFSTLRESTAIKTDRRIRVMNEIVGGMRAIKMYAWEKPFSILVGESRKDEIKVIKKTNTLRAVNMSVFYTSSKIIIFLTLITYVLTENSLTAVKVFVTFALYNNVRLIMTLFFPNGVSQLGEGLVSIRRIENFLLMEER--ITSSKSTLSSHSSIGATGTIKFTNFCANWTPE---QATLNNINLNVGNKELFAIVGHVGSGKTSLLQSILGELPATSGKIRASGTLGYTSQEPWVFSGSVRENILFGRVYDDERYNQVVEACALSRDLDLLPNRDNSLVGEKGSSLSGGQKARITLARAVYANADIYLLDDPLSAVDAEVGRHIFDQCICGILKEKTRILVTHQLHLLQSVNQIVLLEDGFIRAQGNYEKISSFNTTESVLLKNPIRNRTTSEASSSSIPY----VARSGS------FGIGMNEMGVGSTYSINVEEFDDYLDTGCGDDLKTRS--DGVSPSDTLLKSSIPKLNEEISATGRVNLGLYVKYFKSGSNICTLTLLIFGNIATQVLYAGADWWLSFWTKSQEGKSKTNESQPIVS------PLPKSIYHDRDVQIEIYSGLICGLFFASLLRTMVFFNICMTASVNLHESMFLGVLRAPMKFFETNPIGRILSRISKDIGCIDDILPPTMFDTMEIFLNVVGILVLVTIVNYYLLVPAFVIVVVFYFLRKFYLRTARSVKRIEGITRSPVFSHLSTSLSGLSTIRAFKVESNFIKQFDDYQDMHTSSWYIFLAVSRWFGIWLDWISVSWIAFVTFSFMFFNDSGA------------NIGLAVSSAMTLTGMCQWGVRQSAEVENQMVSVERVMEYTQLEPEASLETPKGKTP-PPNDWPSSGEIIFEHVQLKYGN-EEPVLKDITCVIKPSEKIGIVGRTGAGKSSLISALFRIAEPTGSILIDGLDILNLGLQVLRSHISIIPQDPVLFTGTLRVNLDPFNSFRDSELWDVLEQVHLAHDVKQLASGLDMEISEGGANFSLGQRQLVCLARAILKNNKILVLDEATSNIDNDTDTLIQGTIRTKFANCTVLSVAHRLHTVMDCDKILVLDAGSILEFDEPYTLLQNNKSSLYGLAEQSG--ALADLINISKEAALQR 1326
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|1228368133|ref|XP_021945056.1| (multidrug resistance-associated protein 4-like, partial [Folsomia candida]) HSP 1 Score: 1190.64 bits (3079), Expect = 0.000e+0 Identity = 610/1355 (45.02%), Postives = 874/1355 (64.50%), Query Frame = 0
Query: 12 NPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQV---EDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFI--PEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLM-MAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQ 1360
+P A+ +S FFWWLN G KK L+L DL++ L D S+ L +++++ W +V E+ + +PSL R +IK FG + +GM F EEC IRIAQP+ L + F+P + S + E +L GVVL SA+YTFTHHPYFFGV VGM++RI +LIYRKALRLS A++GKST+G+M NL++NDVSRFD + +F+HYLW GP+Q +V + W G + LAG I++ VP Q ++G+ FS LR TA KTD RIR+M+EI+ G++ IKMYAWE PF+ +V ++R+ E+ VI++T R N S F+TS+K+I+ LI +VL+ + A KVF+T ALYN VRL MTLF P G++ + E LVSI+RI++FLLM ER +S + ++ A W + ++TL N+ L ++ AIVG VGSGKTS+LQ++LGE+P G+I G L Y +QEPWVFSGSVR NILFG + +++Y + +E AL D+ D ++VGE+G +LSGGQKAR++LARA+Y +ADIYLLDDPLSAVDA+VG++++++CI LK K ILVTHQ+ L+ + IV+L+ G I +G Y ++ S T S + P +A + + + +A S + F + +YS+ E + +D K+ + D P + +S+PK++ E +A G V+LG Y YF+SG++ L ++ N+ATQ L+ D WL WT +E + ++ +S P + I + I+ G+ L SL+RT+ FF +C +SVNLH MF ++RAP +FF+ NP+GR+L+R SKD+G ID++LPP + D + IFL+++GI+ ++ + P ++ V+F LRK+YL ++R++KR EGI +SP+FS L++SL GL++IRA+K ES I +FD QD+HTS+WY FLA +RWFG+WLDW+ V ++ F +F+F D + ++G+ ++S + LTGM QWG+RQ+AE+EN M S ERV+EY ++E EA L+ P WP G I +V+L+YG E+ VLK + V K EKIGIVGRTGAGKSSLI ALFR+ EPTG IL+DG++I +GL LR ISIIPQDP++F G+LR NLDPFN ++D+++W L++ HL ++ + G++ E+SEGG+N S GQRQLVCLARAIL+NNKIL+LDEAT+N+D TD IQ TIR +FA+CTVL++AHRLHTVMD D+ILV+ G + EF PY LLQ+ S L L G +L I++E+ L++
Sbjct: 2 SPYLKANIISKLFFWWLNAFFGKGNKKALDLGDLYQALPNDRSKFLGDRIEQLWKEEVKRCEEGKKPRKPSLRRVIIKQFGAYYMMVGMLAFLEECFIRIAQPICLGLLLHSFSP-EYSASKTEKWLSAAGVVLGSAMYTFTHHPYFFGVQYVGMKIRIACCSLIYRKALRLSQAALGKSTIGEMTNLISNDVSRFDQSTIFLHYLWIGPIQTAIVTGILWHFYGVACLAGLSILVLFVPFQGYMGKRFSTLRESTAIKTDRRIRVMNEIVGGMRAIKMYAWEKPFSILVGESRKDEIKVIKKTNTLRAVNMSVFYTSSKIIIFLTLITYVLTENSLTAVKVFVTFALYNNVRLIMTLFFPNGVSQLGEGLVSIRRIENFLLMEER--ITSSKSTLSSHSSIGATGTIKFTNFCANWTPE---QATLNNINLNVGNKELFAIVGHVGSGKTSLLQSILGELPATSGKIRASGTLGYTSQEPWVFSGSVRENILFGRVYDDERYNQVVEACALSRDLDLLPNRDNSLVGEKGSSLSGGQKARITLARAVYANADIYLLDDPLSAVDAEVGRHIFDQCICGILKEKTRILVTHQLHLLQSVNQIVLLEDGFIRAQGNYEKISSFNTTESVLLKNPIRNRTTSEASSSSIPY----VARSGS------FGIGMNEMGVGSTYSINVEEFDDYLDTGCGDDLKTRS--DGVSPSDTLLKSSIPKLNEEISATGRVNLGLYVKYFKSGSNICTLTLLIFGNIATQVLYAGADWWLSFWTKSQEGKSKTNESQPIVS------PLPKSIYHDRDVQIEIYSGLICGLFFASLLRTMVFFNICMTASVNLHESMFLGVLRAPMKFFETNPIGRILSRISKDIGCIDDILPPTMFDTMEIFLNVVGILVLVTIVNYYLLVPAFVIVVVFYFLRKFYLRTARSVKRIEGITRSPVFSHLSTSLSGLSTIRAFKVESNFIKQFDDYQDMHTSSWYIFLAVSRWFGIWLDWISVSWIAFVTFSFMFFNDSGA------------NIGLAVSSAMTLTGMCQWGVRQSAEVENQMVSVERVMEYTQLEPEASLETPKGKTP-PPNDWPSSGEIIFEHVQLKYGN-EEPVLKDITCVIKPSEKIGIVGRTGAGKSSLISALFRIAEPTGSILIDGLDILNLGLQVLRSHISIIPQDPVLFTGTLRVNLDPFNSFRDSELWDVLEQVHLAHDVKQLASGLDMEISEGGANFSLGQRQLVCLARAILKNNKILVLDEATSNIDNDTDTLIQGTIRTKFANCTVLSVAHRLHTVMDCDKILVLDAGSILEFDEPYTLLQNNKSSLYGLAEQSG--ALADLINISKEAALQR 1316
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|1325294948|ref|XP_023330581.1| (multidrug resistance-associated protein 4-like [Eurytemora affinis]) HSP 1 Score: 1189.48 bits (3076), Expect = 0.000e+0 Identity = 618/1352 (45.71%), Postives = 885/1352 (65.46%), Query Frame = 0
Query: 8 IQRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETR------KSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRR-----FSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEA----QANTTMS--SASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVG 1342
IQ +NPRENA+ SI FWWL PLL GYKK+LE+ D++ L+ DGSE L +L R W+ ++E + R + SL +A+++ FG + LG+ EEC IR+ QP+ + W ++YF+PG N + EA +Y G+V+ S LYT HHPY+ VM VGMR RI + + I+RK L+LSS + ++T+GQM+NL++NDV+RFD LF HYLW PLQLI+V L W+++G S L GA +++ +PLQ W+G+ ++LR++TA KTD RIR+M EIINGIKVIKM+ WE FT+ V++ R++E+ +IR+T+YFR FNFSFFFT+++ ILL F ++ +++ EK FL L+LYNTVR+SMTLF P I+++ VSI RIQ FLL+ E + + T + V + T W+ E TL +L L K GQ+VA+VGPVG+GKTS+LQ++LGE+P G++N+ G ++Y QEPW+F+GS+R NILFG+++ ++KY + ALE D+ QW D+T VGE+GV LSGGQK+R++LARAIYR A YLLDDPLSAVD+QVGK+++ +CI+ LK VILVTHQ+Q+LK AD IVVLK+G ++ GTY L++ G D S ++ T+ + I +E L+ SD V + F+ S SE S+ + + S + + K+L E ++ +L N +I E ++GSV+ + YF+ G + +++LIL + Q +++ D W+ WT EE E Q N T SDE + + I+ + +L+++S++RTIHFF C SSV LH MF ++ A +FFD NP GR+LNR SKD G +DELLP D +S+ +++GI+ VI+F P PT ++A +F+ LRK+Y+ S+R IKR EGI+++P+ SQ+++S+ GL SIRA+ A+ ++ +EFDR+QDIH+S WY+F++ TRWFGLWLDW+V++YL + +F F+ E + GDVG+ +TSCI +TGMLQWG+RQ+AE ENLMTS ER+LEY + E K P+ + WP +GVIE +NV L+Y E E +L + F T+ EKIGIVGR+GAGKSS+I AL RL EPTG I +DG NI ++ L +LR ISIIPQ L+F G+LR+NLDP DA IW+ L+E L +A++++ +G+E+ +S ++ S GQRQL+CLARA+ N+IL+LDEAT+N+D TD IQ IR RF +CTVLTIAHRL T+MDSDR++V+ G++ EF+SP L ++ V S L +G
Sbjct: 5 IQPQNPRENANIFSIGLFWWLFPLLGKGYKKDLEIEDIYENLKADGSEKLGTELLREWNKELEKQRRLESLGQNYQASLTKALVRQFGPFYALLGIIMCIEECCIRVFQPVLMGWMLNYFSPGSN-MQINEALMYAGGLVVCSLLYTIIHHPYYLEVMHVGMRARIAVCSAIFRKVLKLSSKGLEQTTLGQMINLISNDVNRFDQFVLFFHYLWISPLQLIVVTFLLWQKIGISALVGAILLLLFIPLQIWVGKKLTQLRMQTAGKTDNRIRLMDEIINGIKVIKMFTWENLFTEKVEEARKEEIKIIRKTSYFRSFNFSFFFTASRFILLCTFFLFYITGEILTPEKAFLCLSLYNTVRVSMTLFFPSAISLLGVTKVSISRIQTFLLLEEFSVENDRRYLKS-----TTEVCVEMINFTGKWNK----EYTLNDLTLSVKPGQLVAVVGPVGAGKTSLLQSILGELPLFSGQLNVSGYIAYCPQEPWIFAGSIRDNILFGKSYCKEKYENVIYACALEQDMLQWPHADQTHVGEKGVGLSGGQKSRITLARAIYRSATCYLLDDPLSAVDSQVGKHIFNECIKGFLKQSAVILVTHQLQHLKAADKIVVLKEGRVQEIGTYDNLVNFGVDLSAYL-SLTKNIETPIDDKIE----LLTLSDEKTVLNQILQDGFNKSSPSEDLDYEKSLLQKELKSESVLL----KNLQEPALAETHKLISENIKQEIPKELKSVGSVNKDVFLKYFQIGDNWFSTISMLILLILCQVIYSGSDFWISYWTRIEEINQREILMKHQTNGTHFRLEESDEAESFFYVG--------IYSALIGSLIVISMMRTIHFFQTCIKSSVKLHNQMFLSLMGATCQFFDTNPAGRILNRCSKDTGLMDELLPETFFDALSVLFTLIGIMSVIIFLIPWTLLPTLVLATIFLYLRKFYMRSARDIKRIEGISRAPVISQMSTSISGLVSIRAFSAQQLISAEFDRLQDIHSSTWYTFISGTRWFGLWLDWIVLVYLICVILSFFFL----QGEVI------GGDVGLAITSCIQMTGMLQWGVRQSAEAENLMTSVERILEYSNLPQE---KNKPSPEELPIKLWPVQGVIEFKNVCLRYVENEPSILSSISFKTEPCEKIGIVGRSGAGKSSIITALLRLAEPTGNIYIDGQNIMKMRLTDLRSSISIIPQTSLIFSGTLRENLDPLKRKSDADIWRVLEEFQLVEAVKNLGKGLESPISNSDASFSVGQRQLICLARAVFEENRILVLDEATSNIDRTTDKLIQNMIRTRFFNCTVLTIAHRLETIMDSDRVMVIQQGKIVEFASPDILRKNNGGVFSHLAREIG 1316
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|632947293|ref|XP_007888977.1| (PREDICTED: multidrug resistance-associated protein 4 [Callorhinchus milii]) HSP 1 Score: 1169.84 bits (3025), Expect = 0.000e+0 Identity = 627/1390 (45.11%), Postives = 888/1390 (63.88%), Query Frame = 0
Query: 9 QRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVE-DETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQ--NSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDATSSHGRIHDESPPMETP-ISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQA--NSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQNKPFMEDEEYAEAEEMNLQVTVEDDEKFITKL 1392
++ NP E A+ S FF WLNPL ++GY++ LE D+++ L DGSE+L +LQRHWD +V+ E P L +A++K F + LG FTF EE IR+AQP+ L + YF + V R A+ Y GV L + HH YFF V R GM++R+ + +IYRKALRL++ ++GK+T GQ+VNLL+NDV++FD A +F+H+LW GPLQ I V+ L W+E+G S LAG I++ +P+Q+ G++FS LR +TA TD RIR M+E+I+ +++IKMYAWE PF ++ R+KE+ I +++Y RG N + FF ++K+IL +VL I A +VF+T++LYN VRL++TLF P I VSE L+SIKRI+ FL++ E + H+E+ +E SV ++ LT WD + S L+N+ K G+++A++GPVG+GKTSIL A+LGE+ D G INI+G+++Y AQ+PWVF G+VR NI+FG+ F + KY K + V AL+ D+ + GD T +G+RGV LSGGQKARV+LARA+Y+DADIYLLDDPLSAVDA+VG++L+E+CI L+ K ILVTHQ+QYL A I+++K+G + +GT+TELL SG DF+ + +H EED+ + LE + R+R+ S S ++++ G S E + +G+ ++ P+ ES + GSV Y YF +GA + VL +L+L+L Q + D WL W +E Q N T ++ T+ E++ L + G+TLA+++ +VR++ F + +SS LH MF IIRAP FFD NP+GR+LNRFSKD+G +D+LLP D FL ILG+V V V P + C + ++F LR+Y+L +SR IKR E +SP FS L+SSL G+ +IRA K E ++FD QD+H+ AW+ FL T+RWF + LD L ++ V T F GS + + SG VG+ L+ I L GM QWG+RQ+AE+ENLMTS ERVLEY +++SEA + P P+ WP +G + V Y VLK ++ +SKEK+G+VGRTGAGKSSLI ALFRL EP G+I++DG+ E+GLHELR +SIIPQDP++F GS+RKNLDPFNE+ D +W+AL+E L + + +P +E +++E GSN S GQRQLVCLARAILR +KILI+DEATANVDPRTD IQ+TIR+RF CTVLTIAHRL+T++DSDRILV+ GRV E+ PY LL++ + S++V ++G++ L IA++ +LR K E +Y+E + + D+ F T L
Sbjct: 8 EKRNPMETANLFSHIFFCWLNPLFQIGYRRRLEEEDMYKVLPEDGSEMLGEELQRHWDQEVQVAEKEARNPHLGKAILKCFWKSYIVLGAFTFVEET-IRVAQPILLGKIILYFENNDPDDVVKRGVAFSYAGGVSLCTLALAILHHLYFFHVQRAGMKLRVAMCHMIYRKALRLNNVALGKTTTGQIVNLLSNDVNKFDQATIFLHFLWVGPLQAIAVIALLWQEIGPSCLAGVVILLILMPVQTICGKLFSVLRGKTAVLTDNRIRTMNEVISAMRIIKMYAWEKPFANLIDQIRKKEISQILKSSYLRGLNMASFFIASKMILFFTFTVYVLLGNPITASRVFVTVSLYNAVRLTVTLFFPSAIQTVSEGLISIKRIKRFLILEEIK------KPHEEAHNIEKKDRSVDVQDLTCYWDKTIETPS-LQNIRFTVKPGELLAVIGPVGAGKTSILGAILGELSKDSGIINIKGKIAYCAQKPWVFPGTVRSNIIFGKEFQKAKYEKVITVCALKKDMQMLQDGDLTQIGDRGVTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFEQCITGILQNKPRILVTHQLQYLSAATHILIIKEGKVVQKGTFTELLKSGVDFASLL-KHEEEDE---STGLEPM--------------------LKSTRNRTLSQTS------ILSLGSLGSSAQSIQECILEPVGEPVLSATPE---ESRSEGSVGFQIYKKYFSAGASTFVLFFLLVLSLLAQASYVLQDWWLSYWAANQE------QLNIT--ELLNQNQTVMELDLG--FYLGTYAGLTLAVILFGIVRSLMIFEVLVNSSQELHNRMFNSIIRAPVLFFDQNPIGRILNRFSKDIGHLDDLLPYTCLDFSQTFLQILGVVAVAVSIIPWILISVCPLFIVFFYLRRYFLQTSRDIKRMESTTRSPAFSHLSSSLEGIWTIRATKTEPQFQAKFDDHQDLHSEAWFLFLTTSRWFAVRLDVLCAIF----VTTVAF---GS---ILIANQINSGQVGLALSYAITLMGMFQWGVRQSAEVENLMTSVERVLEYTELQSEAAWESSKPP----PKDWPNKGTVVFDGVNFSYSVNADPVLKNLNLTIRSKEKVGLVGRTGAGKSSLIAALFRLAEPEGKIMIDGILTSELGLHELRQNMSIIPQDPVLFTGSMRKNLDPFNEHDDEALWRALEEVQLKEVVEELPHKMEMQLAESGSNFSVGQRQLVCLARAILRKSKILIIDEATANVDPRTDELIQKTIRERFEQCTVLTIAHRLNTIIDSDRILVLDAGRVTEYDEPYLLLKNNNGQFSKMVQHLGKAEMASLFEIAKKVYLR--KTTSERTQYSETQVNGSAIVSSDNILFETAL 1330
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|913327128|ref|XP_013195006.1| (PREDICTED: probable multidrug resistance-associated protein lethal(2)03659 [Amyelois transitella] >gi|913327130|ref|XP_013195007.1| PREDICTED: probable multidrug resistance-associated protein lethal(2)03659 [Amyelois transitella] >gi|913327132|ref|XP_013195008.1| PREDICTED: probable multidrug resistance-associated protein lethal(2)03659 [Amyelois transitella]) HSP 1 Score: 1167.91 bits (3020), Expect = 0.000e+0 Identity = 617/1448 (42.61%), Postives = 875/1448 (60.43%), Query Frame = 0
Query: 1 MDADDVIIQRENPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMGERDA---------TSSHGRIHDESP-----------------PMETP------ISVSIKGL-------------------------------------TATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMS--EDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETP-----TMEEINASN----------KRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADLKVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESFLRQNK 1362
M+++ + +PR +A+ LS F W P+ G KK +E +DL+ PL S L +K R W+ +V K PSLLR +++ + G F EC IRIAQP+FL V Y++PGQ SV R EAY+Y VVL SAL F HPY ++ +GM+ R+ +LIYRK+LRLS ++G++TVGQ+VNLL+NDV+RFD A +F+HYLW GPL +++ W E+ W+ + G G ++ +PLQ+++G+ S LRL+TA +TD R+R+M+EI++GI+VIKMY WE PF +V R+ E+ IR T+Y RG SF T++ L +I +VL + I A++VF+ + YN +R +MT+F P GIA V+EA +SIKR+Q F+L + TS ++ +E P E+P V ++GL TA W ++ E+TL +L L K G+++A++GPVG+GK+S+L LL E+P G +++ G +SYA+QEPW+F+GSVR NILFG+ +Y + AL+ D + GD+T+VGERGV+LSGGQ+AR+SLAR++Y+ ADIYLLDDPLSAVDA VG++L+E C+ +L+ ILVTHQ+Q+L+D D IV+LK G+I G + L +SG DF+ + + EE A P D +A + R R S+ S S M + A + ED ++ AE + G+VS Y +Y R+ H L++ + + + +Q L + D W G W N EE A TM ++ P + EE SN + I+ GM +ALV++SL+R+ FF M +S LH +MF+ I RAP RFF +NP GR+LNRFSKDMG++DE+LP L DV+ I LS++GIV V+ + PT ++ V+F +LR +YLSSSR+IKR EG+ +SP+FS L ++L G+T+IRA+ A+ LI EFD QD+H+SAWY F+A++R FG WLD + V+Y+G +F+ MG+ G+VG+ +T + LTGM QWGMRQ+ E+EN MTS ER+ EY IESE L+ P+ P SWP G +E R+V L Y GE VLK + V + KEK+GIVGRTGAGKSSLI ALFRL GEI++DG +GLHELR ++SIIPQ+P++F G++R NLDPF+EY D +W+AL+E L +A+ +P G+ + ++EGG N S GQRQLVCLARAI+R N++L+LDEATANVDP+TD IQ TIR +FA+CTVLTIAHRLHTVMDSD++LVM G++ EF P+ LLQ VL +V GR+ L +AR+ + ++++
Sbjct: 1 MESNKKKSRPSHPRASANPLSSLTFAWTLPIFWGGLKKEMEEHDLYEPLDEHSSGPLGDKFARLWEEEVARAGSKRTPSLLRVILRAYAARCMLYGFVLLFMECCIRIAQPVFLGKLVEYYSPGQISVAREEAYVYAALVVLCSALNVFIVHPYMMAILHMGMKFRVACCSLIYRKSLRLSKTALGETTVGQVVNLLSNDVNRFDVAIIFLHYLWIGPLATVIITYFMWLEISWAAVVGVGFMLLFIPLQAYLGKRTSVLRLKTALRTDERVRLMNEILSGIQVIKMYTWEKPFADLVAKARKHEIKQIRATSYIRGVLTSFIMFMTRICLYCSIIVYVLVHNNITAKQVFVITSFYNILRQTMTVFFPQGIAQVAEATISIKRLQSFMLYEDTSKPVPGLADIQTSGKTKVENEDSKDDIVKDKQSLEVPQDVPQESPRVSAADTKVDVEGLKGNGNVNLAPLELGEEDEQELLSRVEQDARGVRLKHATAKWI-ESHPENTLTDLSLTIKPGKLIAVIGPVGAGKSSLLHVLLRELPLQSGSLHVGGTVSYASQEPWLFAGSVRQNILFGQAMDRPRYNAVVRRCALDRDFQMFPHGDKTVVGERGVSLSGGQRARISLARSVYKRADIYLLDDPLSAVDAHVGRHLFESCVVGYLRNTTRILVTHQLQFLRDVDQIVILKNGAIAAAGDFETLSASGLDFASLLARNQEEQVKPAAEQ---------PIDA---EESAAAVLQGSFRKRQMSIHSVSSMDNLTATAPPEDARTEAELRSA---------------------GAVSGAVYGAYLRASGHPLLVAFMTFVAVVSQVLGSGFDWWTGFWVNLEEENPSAVLA--TMEKSNQTGPIEFATSYEEKLVSNVYYSSFDLSRYDCIYIYTGMVVALVVISLLRSFMFFSMAMRASTRLHNNMFQAITRAPMRFFHVNPSGRILNRFSKDMGAVDEVLPAALLDVLQIGLSLIGIVVVVAVVNYWLLVPTMVIGVVFYLLRIFYLSSSRSIKRLEGVTRSPVFSHLNATLQGITTIRAFGAQEALIREFDNHQDLHSSAWYLFIASSRAFGFWLDLVCVVYIGVVTLSFLVMGE----------DEYGGNVGLAITQAMALTGMFQWGMRQSTELENQMTSVERIQEYSNIESEPPLQ--SAPEKKPPPSWPESGRLEFRHVHLYYAPGEPPVLKDLTLVIQPKEKVGIVGRTGAGKSSLINALFRLATIEGEIIIDGRETSTLGLHELRSRVSIIPQEPVLFSGTMRHNLDPFDEYPDQVLWKALEEVELKEAVMELPAGLSSRIAEGGGNFSVGQRQLVCLARAIVRRNRLLVLDEATANVDPQTDALIQTTIRNKFAECTVLTIAHRLHTVMDSDKVLVMDAGQMVEFDHPHVLLQREDGVLRAMVRQTGRAMAGSLGAVARQGYDKKHQ 1400
BLAST of multidrug resistance-associated protein 4 vs. nr
Match: gi|1207971701|ref|XP_021376607.1| (multidrug resistance-associated protein 4-like isoform X1 [Mizuhopecten yessoensis]) HSP 1 Score: 1167.14 bits (3018), Expect = 0.000e+0 Identity = 595/1352 (44.01%), Postives = 870/1352 (64.35%), Query Frame = 0
Query: 12 NPRENASFLSIAFFWWLNPLLRLGYKKNLELNDLFRPLRVDGSEVLNNKLQRHWDSQVEDETRKSEPSLLRAVIKTFGGEFGFLGMFTFFEECGIRIAQPLFLSWFVSYFAPGQNSVGRVEAYLYGLGVVLMSALYTFTHHPYFFGVMRVGMRVRITLSALIYRKALRLSSASMGKSTVGQMVNLLANDVSRFDSACLFIHYLWAGPLQLILVVCLTWREVGWSTLAGAGIVICSVPLQSWIGRVFSRLRLETAKKTDLRIRIMSEIINGIKVIKMYAWELPFTKVVQDTREKEMDVIRRTAYFRGFNFSFFFTSTKVILLAILIPFVLSNQVINAEKVFLTLALYNTVRLSMTLFVPYGIAMVSEALVSIKRIQDFLLMG----ERDATSSHGRIHDESPPMETPISVSIKGLTATWDHQAQGESTLKNLGLQAKAGQMVAIVGPVGSGKTSILQALLGEIPTDQGEINIQGRLSYAAQEPWVFSGSVRHNILFGETFVEKKYLKTLEVSALEHDIGQWEFGDRTMVGERGVALSGGQKARVSLARAIYRDADIYLLDDPLSAVDAQVGKYLYEKCIQTHLKPKLVILVTHQIQYLKDADLIVVLKKGSIEGRGTYTELLSSGTDFSEFIPEHTEEDDDAIAGDLEHLNDLMAPSDTLCVPRRFSASVTSEIRHRSYSVGSESIMSLMMAMSEDGKSLAEFDESDPKELGQANSVPKIHTESAALGSVSLGTYWSYFRSGAHSLVLLAVLILNLATQGLFTFIDVWLGIWTNQEESQMYEAQANTTMSSASDETPTMEEINASNKRNLIIFGGMTLALVIMSLVRTIHFFLMCKDSSVNLHYDMFKKIIRAPSRFFDINPVGRVLNRFSKDMGSIDELLPPVLTDVISIFLSILGIVGVIVFYQPIVFFPTCIMAVLFVMLRKYYLSSSRAIKRSEGIAKSPIFSQLASSLGGLTSIRAYKAESILISEFDRIQDIHTSAWYSFLATTRWFGLWLDWLVVLYLGFCVGTFIFMGDGSSHEAMFSVGSQSGDVGVVLTSCIMLTGMLQWGMRQTAEMENLMTSTERVLEYGKIESEADL--KVDHHPDMFQPESWPREGVIECRNVRLQYGEGEKHVLKGVDFVTKSKEKIGIVGRTGAGKSSLIVALFRLTEPTGEILVDGVNIQEIGLHELRHQISIIPQDPLVFHGSLRKNLDPFNEYQDAQIWQALKEAHLDQAIRSMPQGIETEMSEGGSNLSAGQRQLVCLARAILRNNKILILDEATANVDPRTDGWIQETIRKRFADCTVLTIAHRLHTVMDSDRILVMSDGRVAEFSSPYDLLQDRHSVLSELVSNVGRSTQLELRRIARESF 1357
NP A+ +S FFWWLNP GYK+ LE++DLF ++ D SE L N+L++ W+ +++ + + SLL+A+++ FG ++ LG+ F EE G ++ QPL L + YF P ++V +AYLY +GV L + + HHPYFFGV R+GM++R+ +L+YRK+LRLS+ ++G++T GQ+VNL++NDV+RFD+A +F+HYLW GP Q I V+ + W+E+G STLAG +++ VP+QSW+G++FS+LR +TA TD R+++M+EII G++VIKMY WE PF ++V R++E+ ++ ++Y RGF FF S K+I+ + +VL+ + EKVF+T++LY VRLS TLF+P+ + +E V+ R+Q FLL+ ER T +I D V I +TA WD + + + TLKN+ ++ G+++A++GPVG+GK+S+L ++L EIP +G++ ++GR++Y +Q+ WVFS S+R NI+FG F KKY + L+ AL D+ GD T++G+RGV+LSGGQ+ARVSLARA+Y DAD+YLLDDPLSAVDA V ++L+E IQ LK K VILVTHQ+Q+L +AD +++LK G G+GT+ E+ SSG DFS + TE+DD+ + +H + +R + ++S S G I S +++ G EF + +P +L + E G++ Y+ YF++G+ +++LNL Q + D WL IW+NQEE + Y Q + + + +N+ IF G+ +A+ + ++R + FF + D+S+NLH MF +++R P FFD NPVGR+LNRFSKD G +D++LP D + FL ILGI+ V+ P VF P + ++F + R Y++ +SR IKR EG +SP+FS L++SL GL SIRA+ + + EFD QD+H+ AW+ FL+T+RW + LDW+ +++ + M S +G VG+ LT + L GM QW +RQ+AE+EN M S ERVL+Y ++E+E DL K H P P WP G I+ NV L+Y + VLK + F K +EK+GIVGRTGAGKSSLI +FRLTE G +L+DGVNIQEIGLH+LR QISIIPQDP++F G LRKNLDPF + D +W AL+E + A+ +P G+E E+SEGG N S GQRQL+CLARAILR N++L++DEATANVDPRTD IQ+TIR +F CTVLTIAHRL+T+MDSDR+LV+ +G + EF PY LLQ+ +V G++ L +AR+ +
Sbjct: 11 NPLLTANPISKVFFWWLNPTFSTGYKRRLEVDDLFNVVKCDSSEELGNRLEKEWEKELKKQESGGKASLLKALVRMFGFQYMLLGIIVFIEE-GTKVVQPLLLGQLIRYFTP-DSTVSERDAYLYAMGVSLCAIVLAVAHHPYFFGVQRIGMQMRVACCSLLYRKSLRLSNTALGQTTTGQIVNLMSNDVNRFDTAAIFLHYLWVGPCQAIPVLIILWQELGPSTLAGFVVLLLLVPVQSWMGKLFSKLRHKTAIHTDERVKVMNEIITGMRVIKMYCWEKPFGELVSKLRKREIHRVKESSYTRGFIVGPFFVSAKLIVFLTFLSYVLNGGTMTPEKVFVTISLYQAVRLSTTLFIPFAVQFSAETRVTSSRLQKFLLLDELKVERPITGIRPQIRD--------CMVKIDNITANWDEKIE-QPTLKNISVEVGHGKLLAVIGPVGAGKSSLLMSVLKEIPLSEGKVTVKGRIAYVSQQAWVFSASLRQNIVFGGVFDNKKYNRVLKACALHKDMDMMPQGDSTLIGDRGVSLSGGQRARVSLARALYMDADVYLLDDPLSAVDAAVSRHLFENVIQGVLKSKPVILVTHQLQFLAEADELIILKDGECVGQGTFEEMASSGVDFSSLL--KTEKDDEEDNEEEQH------------ILQRLDSHISSR------SPGPSDIGS-TFSLTSIG---TEF-QPEPVQLPEE--------EERKGGTIGWKVYFEYFKAGSGVFSFTILVLLNLLAQVSYVMSDWWLSIWSNQEEHRHYMIQQDQALRDLGHNITNITIPYVDTHQNIYIFTGIIVAVFLFGILRALMFFKVAVDASMNLHNGMFNRLLRVPIAFFDTNPVGRILNRFSKDTGHMDDMLPITFFDFVQCFLLILGIILVVCVVNPWVFIPLVPLCIVFYVTRTYHIKTSRHIKRLEGTTRSPVFSHLSASLQGLHSIRAFSIQDKFMEEFDNHQDLHSEAWFMFLSTSRWLAVRLDWICAMFVTVVALLSVLM----------SKDMDAGKVGLSLTYAMTLMGMFQWAVRQSAEVENQMISVERVLDYSRLETEGDLESKKGHKP----PPEWPPNGEIKGTNVTLKYSKTGPLVLKHLSFYIKGREKVGIVGRTGAGKSSLIAMMFRLTEHGGNVLLDGVNIQEIGLHDLRKQISIIPQDPVLFTGPLRKNLDPFCNHDDNHLWNALEEVQMKVAVEDLPGGLEAEVSEGGINFSVGQRQLICLARAILRKNRVLMIDEATANVDPRTDELIQKTIRDKFRQCTVLTIAHRLNTIMDSDRVLVLDEGNIVEFDQPYLLLQNEEGNFYRMVQQTGKTEADHLLEVARDCY 1304 The following BLAST results are available for this feature:
BLAST of multidrug resistance-associated protein 4 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 17
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BLAST of multidrug resistance-associated protein 4 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of multidrug resistance-associated protein 4 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold438_size171652:8935..16057+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>snap_masked-scaffold438_size171652-processed-gene-0.1 ID=snap_masked-scaffold438_size171652-processed-gene-0.1|Name=multidrug resistance-associated protein 4|organism=Tigriopus kingsejongensis|type=gene|length=7123bp|location=Sequence derived from alignment at scaffold438_size171652:8935..16057+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'multidrug resistance-associated protein 4' has the following synonyms
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