The Phe362Tyr mutation conveying resistance to organophosphates occurs in high frequencies in salmon lice collected from wild salmon and trout

Overview
TitleThe Phe362Tyr mutation conveying resistance to organophosphates occurs in high frequencies in salmon lice collected from wild salmon and trout
AuthorsFjørtoft HB, Besnier F, Stene A, Nilsen F, Bjørn PA, Tveten AK, Finstad B, Aspehaug V, Glover KA
TypeJournal Article
Journal NameScientific reports
Volume7
Issue1
Year2017
Page(s)14258
CitationFjørtoft HB, Besnier F, Stene A, Nilsen F, Bjørn PA, Tveten AK, Finstad B, Aspehaug V, Glover KA. The Phe362Tyr mutation conveying resistance to organophosphates occurs in high frequencies in salmon lice collected from wild salmon and trout. Scientific reports. 2017 Oct 27; 7(1):14258.

Abstract

The parasitic salmon louse, and its resistance to chemical delousing agents, represents one of the largest challenges to the salmon aquaculture industry. We genotyped lice sampled from wild salmon and sea trout throughout Norway with the recently identified Phe362Tyr mutation that conveys resistance to organophosphates. These results were compared to data from lice sampled on farmed salmon in the same regions. The resistant (R) allele was observed in salmon lice from wild salmon and sea trout throughout Norway, although its frequency was highest in farming-intense regions. In most regions, the frequency of the R allele was higher in lice collected from wild sea trout than wild Atlantic salmon, and in all regions, the frequency of the R allele was similar in lice collected from wild sea trout and farmed Atlantic salmon. The R allele is only selected for in fish-farms where organophosphates are used for delousing. Therefore, our results suggest extensive exchange of lice between farmed and wild hosts, and indicate that in farming-dense regions in Norway, aquaculture represents a major driver of salmon louse population structure. Finally, these data suggest that the wild hosts within the regions studied will not delay the spread of resistance when organophosphates are used.

Properties
Additional details for this publication include:
Property NameValue
Publication ModelElectronic
ISSN2045-2322
eISSN2045-2322
Publication Date2017 Oct 27
Journal AbbreviationSci Rep
DOI10.1038/s41598-017-14681-6
Elocation10.1038/s41598-017-14681-6
LanguageEnglish
Language Abbreng
Publication TypeJournal Article
Journal CountryEngland
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PMID: PMID:29079820