RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Titlesort ascending Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Posted Publication
1 Z F220 EMLSAT00000004214, EMLSAT00000004214-700061 (mRNA) Lepeophtheirus salmonis
TOR
PreAdult2 female reproduction, shorter eggstrings 30/17 Lepeophtheirus salmonis F>50.00% 3 September, 2015 - 08:53
Molecular characterization and functional analysis of...
2 Z F219 CMi2471 (negative control), CMi2471 (PCR_product) Gadus morhua
CMi2471
PreAdult2 no visible phenotype 30/19 Lepeophtheirus salmonis 3 September, 2015 - 08:46
3 Z F218 CTH210 (negative control), CTH210 (PCR_product) Gadus morhua
CTH210
PreAdult2, Adult no visible phenotype 30/17 Lepeophtheirus salmonis 3 September, 2015 - 08:44
4 Z F215 EMLSAG00000000440, EMLSAG00000000440-683206 (gene) Lepeophtheirus salmonis
440
PreAdult2, Adult no visible phenotype 30/16 Lepeophtheirus salmonis 3 September, 2015 - 09:23
5 Z F214 EMLSAG00000000426, EMLSAG00000000426-683192 (gene) Lepeophtheirus salmonis
426
PreAdult2, Adult Many bad and short eggstrings.
female reproduction, shorter eggstrings
30/19 Lepeophtheirus salmonis 3 September, 2015 - 09:21
6 Z F205 EMLSAG00000000367, EMLSAG00000000367-683133 (gene) Lepeophtheirus salmonis
367
PreAdult2, Adult no visible phenotype 30/19 Lepeophtheirus salmonis 3 September, 2015 - 09:15
7 Z F204 EMLSAG00000000106, EMLSAG00000000106-682872 (gene) Lepeophtheirus salmonis
106
PreAdult2, Adult Slightly wavy ES-check hatching
female reproduction, egg string deformation
30/20 Lepeophtheirus salmonis 3 September, 2015 - 09:12
8 Z F198 EMLSAG00000000527, EMLSAG00000000527-683293 (gene) Lepeophtheirus salmonis
527
PreAdult2, Adult slightly wavy ES-check hatching
female reproduction, egg string deformation
30/20 Lepeophtheirus salmonis 3 September, 2015 - 09:31
9 Z F197 EMLSAT00000000563, EMLSAT00000000563-696410 (mRNA) Lepeophtheirus salmonis
563
PreAdult2, Adult no visible phenotype 30/26 Lepeophtheirus salmonis 3 September, 2015 - 09:28
10 Z F0 CPY185 (negative control), CPY185 (PCR_product) Gadus morhua
CPY185
PreAdult2, Adult Control 30/18 Lepeophtheirus salmonis 3 September, 2015 - 08:41

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