RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Titlesort descending Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Posted Publication
161 F235 EMLSAT00000003009, EMLSAT00000003009-698856 (mRNA) Lepeophtheirus salmonis
EMLSAG00000003009
Adult, Adult 30/24 Lepeophtheirus salmonis 12 April, 2016 - 11:07
162 F367 EMLSAT00000005299 nauplia EMLSAT00000005299, EMLSAT00000005299-701146 (mRNA) Lepeophtheirus salmonis
EMLSAT00000005299
Nauplius1 200 Lepeophtheirus salmonis 29 May, 2018 - 15:16
163 F F41 EMLSAG00000000807, EMLSAG00000000807-683573 (gene) Lepeophtheirus salmonis
g19454_iCAT
PreAdult2 No visible phenotype 10 Lepeophtheirus salmonis 26 March, 2018 - 12:15
164 Functional characterization of a heme Peroxidase (female) F159 EMLSAT00000001069, EMLSAT00000001069-696916 (mRNA) Lepeophtheirus salmonis
HPX1
PreAdult1, PreAdult2/Adult Fall off the fish
survival, reduced
42 Lepeophtheirus salmonis F>78.00% 16 February, 2017 - 17:49
Molecular characterization and functional analysis of a...
165 Functional characterization of a heme Peroxidase (male) F159 EMLSAT00000001069, EMLSAT00000001069-696916 (mRNA) Lepeophtheirus salmonis
HPX1
padII/ad, Adult Fall off the fish
survival, reduced
42/1 Lepeophtheirus salmonis F>98.00% 21 February, 2017 - 09:56
Molecular characterization and functional analysis of a...
166 Functional characterization of a heme Peroxidase (Nauplia) F159 EMLSAT00000001069, EMLSAT00000001069-696916 (mRNA) Lepeophtheirus salmonis
HPX1
Nauplius1, Copepodid Decreased swimming activity
Motility, reduced
400/400 Lepeophtheirus salmonis F>89.00% 21 February, 2017 - 10:04
Molecular characterization and functional analysis of a...
167 G F25 EMLSAT00000002032, EMLSAT00000002032-697879 (mRNA) Lepeophtheirus salmonis
g6339_Cathepsin
PreAdult2 No visible phenotype 35/8 Lepeophtheirus salmonis 26 March, 2018 - 11:06
168 G F30 EMLSAG00000004159, EMLSAG00000004159-686925 (gene) Lepeophtheirus salmonis
g3796_Proton
PreAdult2 No visible phenotype 36/9 Lepeophtheirus salmonis 26 March, 2018 - 11:11
169 G F38 EMLSAT00000007039, EMLSAT00000007039-702886 (mRNA) Lepeophtheirus salmonis
g12979_PEP3
PreAdult2 No visible phenotype 38/10 Lepeophtheirus salmonis 26 March, 2018 - 11:17
170 G F47 EMLSAT00000006459, EMLSAT00000006459-702306 (mRNA) Lepeophtheirus salmonis
g1573
PreAdult2, Adult No visible phenotype 36/12 Lepeophtheirus salmonis 26 March, 2018 - 12:22

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