RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Titlesort descending Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Posted Publication
311 Q F123 placeholder for unknown sequence, geneofdeath (protein_coding_gene) Lepeophtheirus salmonis
UN31_g7083
PreAdult2, Adult Reduced survival
survival, reduced
40/13 Lepeophtheirus salmonis F>10.00% 11 June, 2014 - 14:36
312 Q F149 EMLSAG00000010881, EMLSAG00000010881-693647 (gene) Lepeophtheirus salmonis PreAdult2, Adult 120 Lepeophtheirus salmonis 11 June, 2014 - 13:57
313 Q F173 EMLSAG00000000441, EMLSAG00000000441-683207 (gene) Lepeophtheirus salmonis
PGES
PreAdult2 39 Lepeophtheirus salmonis 10 June, 2014 - 15:33
314 R F124 EMLSAG00000012828, EMLSAG00000012828-695594 (gene) Lepeophtheirus salmonis
UN32_g22197
PreAdult2 Normal
no visible phenotype
39/24 Lepeophtheirus salmonis 7 October, 2014 - 10:26
315 R F125 placeholder for unknown sequence, geneofdeath (protein_coding_gene) Lepeophtheirus salmonis
UN33_g12918
PreAdult2 no visible phenotype 39/18 Lepeophtheirus salmonis 16 December, 2014 - 08:38
316 R F158 EMLSAT00000009936, EMLSAT00000009936-705783 (mRNA) Lepeophtheirus salmonis PreAdult2 Normal
no visible phenotype
39/20 Lepeophtheirus salmonis F>95.00% 20 October, 2014 - 15:32
317 R F161 EMLSAG00000000580, EMLSAG00000000580-683346 (gene) Lepeophtheirus salmonis
UN38_580
PreAdult2, Adult Abnormal eggstrings in some individuals
female reproduction, abnormal egg strings
37/20 Lepeophtheirus salmonis F>99.00% 7 October, 2014 - 10:17
318 R F170 (DcytB) EMLSAG00000005522, EMLSAG00000005522-688288 (gene) Lepeophtheirus salmonis
DcytB
PreAdult2, Adult no visible phenotype 39/19 Lepeophtheirus salmonis 27 July, 2015 - 11:29
319 R F171 (Fepo) EMLSAG00000007383, EMLSAG00000007383-690149 (gene) Lepeophtheirus salmonis
Fepo (Ferroportin)
PreAdult2, Adult no visible phenotype 39/22 Lepeophtheirus salmonis 27 July, 2015 - 12:52
320 Rhabdovirus - No9+127 prod of virus free strain LsRhabNo9.nucleoprotein.g, KJ958535.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No 9, LsRhabNo127.nucleoprotein.g, KJ958536.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No127
N protein LsRV-No9, N protein LsRV-No127
Nauplius I, Adult 480 Lepeophtheirus salmonis F>66.00% 20 April, 2018 - 09:55
RNAi-mediated treatment of two vertically transmitted...

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