RNAi

Search or browse a total of 353 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Titlesort descending Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Posted Publication
81 AX F262 EMLSAG00000006928, EMLSAG00000006928-689694 (gene) Lepeophtheirus salmonis
T19_6928
PreAdult2 normal 30/14 Lepeophtheirus salmonis 5 August, 2019 - 13:39
82 beta FTZ-F1 EMLSAT00000008900, EMLSAT00000008900-704747 (mRNA) Lepeophtheirus salmonis, EMLSAT00000008902, EMLSAT00000008902-704749 (mRNA) Lepeophtheirus salmonis
beta FTZ-F1
Nauplius, Copepodid Developmental arrest
developmental defect, Molting, no molting
0 Lepeophtheirus salmonis F>50.00% 14 June, 2018 - 13:50
83 B F18 EMLSAG00000005090, EMLSAG00000005090-687856 (gene) Lepeophtheirus salmonis
EcR
PreAdult2 No eggstrings 39/14 Lepeophtheirus salmonis F>0.00% 12 December, 2014 - 10:39
Molecular characterisation of the salmon louse,...
84 B F2+F3 (IRP1+IRP2) EMLSAT00000007801, EMLSAT00000007801-703648 (mRNA) Lepeophtheirus salmonis, EMLSAT00000000118, EMLSAT00000000118-695965 (mRNA) Lepeophtheirus salmonis
LsIRP1B, LsIRP1A
PreAdult2, Adult female reproduction, shorter eggstrings 39/23 Lepeophtheirus salmonis F>44.00% 29 April, 2015 - 16:21
Characterisation of iron regulatory protein 1A and 1B in the...
85 C F22 EMLSAT00000003030, EMLSAT00000003030-698877 (mRNA) Lepeophtheirus salmonis
g1751_Tryp1
PreAdult2 39/5 Lepeophtheirus salmonis F>94.00% 4 February, 2015 - 13:04
86 C F23 placeholder for unknown sequence, geneofdeath (protein_coding_gene) Lepeophtheirus salmonis
g3359_Tryp2
PreAdult2 40/10 Lepeophtheirus salmonis F>0.10% 4 February, 2015 - 13:14
87 C F40 EMLSAG00000000441, EMLSAG00000000441-683207 (gene) Lepeophtheirus salmonis
PGES2
PreAdult2 no visible phenotype
no visible phenotype
30/9 Lepeophtheirus salmonis F>0.00% 15 October, 2013 - 12:53
Molecular characterization and knock-down of salmon louse (...
88 C F4 (CopB2) EMLSAT00000000903, EMLSAT00000000903-696750 (mRNA) Lepeophtheirus salmonis
LsCopB2
PreAdult2, Adult feeding, reduced nutrient uptake, no blood uptake, female reproduction, no eggstrings, survival, reduced 39 Lepeophtheirus salmonis F>82.00% 24 July, 2015 - 16:11
RNA interference mediated knockdown of the KDEL receptor and...
89 D F26 placeholder for unknown sequence, geneofdeath (protein_coding_gene) Lepeophtheirus salmonis
g10296_cath
PreAdult2 No visible phenotype 40/7 Lepeophtheirus salmonis F>80.00% 4 February, 2015 - 13:21
90 D F28 EMLSAT00000006302, EMLSAT00000006302-702149 (mRNA) Lepeophtheirus salmonis
g158_glycin_trans
PreAdult2 40/12 Lepeophtheirus salmonis F>42.00% 4 February, 2015 - 13:29

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