RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Titlesort ascending Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Posted Publication
91 Rhabdovirus - No9 prod of virus free strains LsRhabNo9.nucleoprotein.g, KJ958535.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No 9
N protein LsRV-No9
Nauplius I, Adult 480 Lepeophtheirus salmonis F>41.00% 20 April, 2018 - 09:35
RNAi-mediated treatment of two vertically transmitted...
92 Rhabdovirus - No9 prod of virus free strains LsRhabNo9.nucleoprotein.g, KJ958535.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No 9
N protein LsRV-No9
Nauplius I, Adult 480 Lepeophtheirus salmonis F>97.00% 20 April, 2018 - 09:38
RNAi-mediated treatment of two vertically transmitted...
93 Rhabdovirus - No9+127 Specificity LsRhabNo9.nucleoprotein.g, KJ958535.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No 9, LsRhabNo127.nucleoprotein.g, KJ958536.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No127
N protein LsRV-No9, N protein LsRV-No127
Nauplius I, Copepodid 540/540 Lepeophtheirus salmonis F>94.00% 19 April, 2018 - 15:00
RNAi-mediated treatment of two vertically transmitted...
94 Rhabdovirus - No9+127 prod of virus free strain LsRhabNo9.nucleoprotein.g, KJ958535.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No 9, LsRhabNo127.nucleoprotein.g, KJ958536.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No127
N protein LsRV-No9, N protein LsRV-No127
Nauplius I, Adult 480 Lepeophtheirus salmonis F>66.00% 20 April, 2018 - 09:55
RNAi-mediated treatment of two vertically transmitted...
95 Rhabdovirus - No9+127 prod of virus free strain LsRhabNo9.nucleoprotein.g, KJ958535.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No 9, LsRhabNo127.nucleoprotein.g, KJ958536.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No127
N protein LsRV-No9, N protein LsRV-No127
Nauplius I, Adult no visible phenotype 480 Lepeophtheirus salmonis F>100.00% 20 April, 2018 - 10:01
RNAi-mediated treatment of two vertically transmitted...
96 Rhabdovirus - No9+127 prod of virus free strain LsRhabNo9.nucleoprotein.g, KJ958535.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No 9, LsRhabNo127.nucleoprotein.g, KJ958536.nucleoprotein.g (gene) Lepeophtheirus salmonis rhabdovirus No127
N protein LsRV-No9, N protein LsRV-No127
Nauplius I, Adult no visible phenotype 480 Lepeophtheirus salmonis F>98.00% 20 April, 2018 - 10:02
RNAi-mediated treatment of two vertically transmitted...
97 R F171 (Fepo) EMLSAG00000007383, EMLSAG00000007383-690149 (gene) Lepeophtheirus salmonis
Fepo (Ferroportin)
PreAdult2, Adult no visible phenotype 39/22 Lepeophtheirus salmonis 27 July, 2015 - 12:52
98 R F170 (DcytB) EMLSAG00000005522, EMLSAG00000005522-688288 (gene) Lepeophtheirus salmonis
DcytB
PreAdult2, Adult no visible phenotype 39/19 Lepeophtheirus salmonis 27 July, 2015 - 11:29
99 R F161 EMLSAG00000000580, EMLSAG00000000580-683346 (gene) Lepeophtheirus salmonis
UN38_580
PreAdult2, Adult Abnormal eggstrings in some individuals
female reproduction, abnormal egg strings
37/20 Lepeophtheirus salmonis F>99.00% 7 October, 2014 - 10:17
100 R F158 EMLSAT00000009936, EMLSAT00000009936-705783 (mRNA) Lepeophtheirus salmonis PreAdult2 Normal
no visible phenotype
39/20 Lepeophtheirus salmonis F>95.00% 20 October, 2014 - 15:32

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