RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Title Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Postedsort descending Publication
121 D F33 EMLSAT00000002599, EMLSAT00000002599-698446 (mRNA) Lepeophtheirus salmonis
g18363_TSC2
PreAdult2 female reproduction, shorter eggstrings 40/11 Lepeophtheirus salmonis F>72.00% 4 February, 2015 - 13:53
Molecular characterization and functional analysis of...
122 E F35 EMLSAT00000011088, EMLSAT00000011088-706935 (mRNA) Lepeophtheirus salmonis
g18363_LsRictor
PreAdult2 no visible phenotype 40/23 Lepeophtheirus salmonis F>35.00% 4 February, 2015 - 14:37
Molecular characterization and functional analysis of...
123 E F49a EMLSAT00000002641, EMLSAT00000002641-698488 (mRNA) Lepeophtheirus salmonis
ILR frag2
PreAdult2 35/22 Lepeophtheirus salmonis F>0.10% 4 February, 2015 - 14:57
124 E F49b EMLSAT00000002641, EMLSAT00000002641-698488 (mRNA) Lepeophtheirus salmonis
ILR frag2 halv dose
PreAdult2 40/25 Lepeophtheirus salmonis F>0.10% 4 February, 2015 - 14:59
125 H F24 EMLSAT00000002836, EMLSAT00000002836-698683 (mRNA) Lepeophtheirus salmonis
g3536_Tryp3
PreAdult2 40 Lepeophtheirus salmonis F>89.00% 4 February, 2015 - 15:12
126 D F32/F33 EMLSAT00000002599, EMLSAT00000002599-698446 (mRNA) Lepeophtheirus salmonis, EMLSAT00000003443, EMLSAT00000003443-699290 (mRNA) Lepeophtheirus salmonis
g18363_TSC2, NLG3408_TSC1
PreAdult2 female reproduction, shorter eggstrings 40/14 Lepeophtheirus salmonis F>30.00% 5 February, 2015 - 08:46
Molecular characterization and functional analysis of...
127 S F179 EMLSAG00000011173, EMLSAG00000011173-693939 (gene) Lepeophtheirus salmonis PreAdult2 No visible phenotype 30/18 Lepeophtheirus salmonis 26 February, 2015 - 14:28
128 S F180 EMLSAT00000009473, EMLSAT00000009473-705320 (mRNA) Lepeophtheirus salmonis PreAdult2 No visible phenotype but significant reduction in 30/24 Lepeophtheirus salmonis 26 February, 2015 - 14:41
129 S F183 EMLSAT00000011090, EMLSAT00000011090-706937 (mRNA) Lepeophtheirus salmonis PreAdult2 Normal egg strings 30/18 Lepeophtheirus salmonis 26 February, 2015 - 15:15
130 T F182 EMLSAG00000012145, EMLSAG00000012145-694911 (gene) Lepeophtheirus salmonis PreAdult2 some animals with Zig Zag egg strings + 40% reduct 30/12 Lepeophtheirus salmonis 26 February, 2015 - 15:39

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