RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Titlesort descending Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Posted
131 EMLSAT00000001458 cop + infection EMLSAT00000001458, EMLSAT00000001458-697305 (mRNA) Lepeophtheirus salmonis
RAB1A
Nauplius1, Copepodid no lice survived to the end of experiment, where c
survival, reduced
60 Lepeophtheirus salmonis 14 June, 2018 - 11:36
132 EMLSAT00000001458 cop + infection_b EMLSAT00000001458, EMLSAT00000001458-697305 (mRNA) Lepeophtheirus salmonis
RAB1A
Nauplius1, Copepodid no lice survived to the end of experiment, where c
survival, reduced
100 Lepeophtheirus salmonis 6 August, 2018 - 16:19
133 EMLSAT00000002095_copepodites EMLSAT00000002095, EMLSAT00000002095-697942 (mRNA) Lepeophtheirus salmonis
Astacin
Copepodid, Copepodid host related phenotype, modulation of immune response 420/50 Lepeophtheirus salmonis F>94.00% 14 June, 2018 - 13:12
134 EMLSAT00000003179 cop + infection EMLSAT00000003179, EMLSAT00000003179-699026 (mRNA) Lepeophtheirus salmonis
Csdc2
Nauplius1, Copepodid no proper visible phenotype but maybe quicker deve
no visible phenotype
180/45 Lepeophtheirus salmonis 14 June, 2018 - 13:09
135 EMLSAT00000004874_Var2Frag1 EMLSAT00000004874, EMLSAT00000004874-700721 (mRNA) Lepeophtheirus salmonis
Heme peroxidase
Copepodid, PreAdult no visible phenotype 60 Lepeophtheirus salmonis F>20.00% 14 June, 2018 - 12:49
136 EMLSAT00000004874_Var2Frag1 EMLSAT00000004874, EMLSAT00000004874-700721 (mRNA) Lepeophtheirus salmonis
Heme peroxidase
Nauplius1, Copepodid no visible phenotype Lepeophtheirus salmonis F>77.00% 14 June, 2018 - 13:19
137 EMLSAT00000004874_Var2Frag2 EMLSAT00000004874, EMLSAT00000004874-700721 (mRNA) Lepeophtheirus salmonis
Heme peroxidase
Copepodid, PreAdult no visible phenotype 60 Lepeophtheirus salmonis F>15.00% 14 June, 2018 - 12:53
138 EMLSAT00000004874_Var2Frag2 EMLSAT00000004874, EMLSAT00000004874-700721 (mRNA) Lepeophtheirus salmonis
Heme peroxidase
Nauplius1, Copepodid no visible phenotype 60 Lepeophtheirus salmonis F>61.00% 14 June, 2018 - 13:23
139 EMLSAT00000005299 cop + infection EMLSAT00000005299, EMLSAT00000005299-701146 (mRNA) Lepeophtheirus salmonis
Emc3
Nauplius1, chalimus and preadult no proper visible phenotype but maybe quicker deve
no visible phenotype
180/52 Lepeophtheirus salmonis 14 June, 2018 - 14:05
140 EMLSAT00000006642_copepodites EMLSAT00000006642, EMLSAT00000006642-702489 (mRNA) Lepeophtheirus salmonis Copepodid 420/66 Lepeophtheirus salmonis F>86.00% 4 December, 2017 - 10:28

Pages