EMLSAG00000000293, EMLSAG00000000293-683059 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0000228 "nuclear chromosome" evidence=IEA] [GO:0000932 "cytoplasmic mRNA processing body" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003682 "chromatin binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005654 "nucleoplasm" evidence=IEA] [GO:0005730 "nucleolus" evidence=IEA] [GO:0006260 "DNA replication" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0040016 "embryonic cleavage" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0043204 "perikaryon" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005694 GO:GO:0003677 GO:GO:0006200 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 EMBL:AADN03007800 EMBL:AADN03007851 Ensembl:ENSGALT00000042945 Uniprot:R4GM79) HSP 1 Score: 630.172 bits (1624), Expect = 0.000e+0 Identity = 327/553 (59.13%), Postives = 399/553 (72.15%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDE-DQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS++ EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE+ IT+LSKCDF ++ Y+K +E RK SKEEK+ KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT+ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT DDN+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A ++LK AK K K ++ KKKA++R EQL KLE QA D+EENK IAL TSKLNYLDPRISVAW KK+ +PIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 196 EGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSTKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTSEEKSTITSLSKCDFTHMSQYFKAQTEARKQMSKEEKQKIKEENERLLKEYGYCVMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDSKVPPPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTNPDDNIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRELKSAKADAKVRRDEKSKKAVESKKKAVQRIEEQLMKLEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMAEEDYEF 748
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005694 GO:GO:0003677 GO:GO:0006200 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 EMBL:AADN03007800 EMBL:AADN03007851 Ensembl:ENSGALT00000005832 OMA:XEMTNDE ArrayExpress:F1NPT1 Uniprot:F1NPT1) HSP 1 Score: 630.172 bits (1624), Expect = 0.000e+0 Identity = 327/553 (59.13%), Postives = 399/553 (72.15%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDE-DQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS++ EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE+ IT+LSKCDF ++ Y+K +E RK SKEEK+ KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT+ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT DDN+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A ++LK AK K K ++ KKKA++R EQL KLE QA D+EENK IAL TSKLNYLDPRISVAW KK+ +PIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 195 EGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSTKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTSEEKSTITSLSKCDFTHMSQYFKAQTEARKQMSKEEKQKIKEENERLLKEYGYCVMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDSKVPPPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTNPDDNIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRELKSAKADAKVRRDEKSKKAVESKKKAVQRIEEQLMKLEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMAEEDYEF 747
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:top1l "topoisomerase (DNA) I, like" species:7955 "Danio rerio" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA;IBA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA;IBA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0031298 "replication fork protection complex" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0005730 "nucleolus" evidence=IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0016853 "isomerase activity" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 ZFIN:ZDB-GENE-060616-217 GO:GO:0007059 GO:GO:0005730 GO:GO:0003677 GO:GO:0006260 GO:GO:0006200 GO:GO:0006338 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 HOGENOM:HOG000105469 HOVERGEN:HBG007988 KO:K03163 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 OMA:DHAKNPT EMBL:CR548630 EMBL:BC117588 RefSeq:NP_001037789.1 UniGene:Dr.67676 Ensembl:ENSDART00000065949 GeneID:553496 KEGG:dre:553496 CTD:553496 InParanoid:Q1ED17 NextBio:20880241 PRO:PR:Q1ED17 Uniprot:Q1ED17) HSP 1 Score: 622.083 bits (1603), Expect = 0.000e+0 Identity = 326/553 (58.95%), Postives = 398/553 (71.97%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY---------------------SKSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DG KWKFL+H+GP+FAP Y+ LP V FYY+ K MKLS EEVA F+++ ++HEYT K++F +NFFKDWRK MT EE+ IT+L+KCDF ++ Y+K SE RK +KEEK KE+N I E+G C++DNH E+I NFRIEPPGLFRGR +G + R+ +K ++RH +K + +IK K + YE AR LK +++IR Y D+KSKEM++RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEH+TLH DG+++ VEFDFLGKDSIRY+N VPVEKRVFKN+QLFME+K EDDLFDRLNT+ILN++L LM GLTAKVFRT+NAS TLQ QL ELT ++DNVPAK+LSYNRANR VAILCNHQRA PKT +KSMQNLQ KI AK+E +A+++LK AK K K ++ KKKAL+R EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KKF +PIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 206 DGVKWKFLEHKGPVFAPPYEPLPSNVKFYYDGKHMKLSPNAEEVATFFSKMLDHEYTTKDIFRKNFFKDWRKEMTSEEKSKITDLNKCDFSNMSEYFKAQSEARKAMTKEEKLKIKEENERILQEYGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPTPPPGTKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDRIRSQYRDDWKSKEMKIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHLTLHPEMDGQEFVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMEDKEPEDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLNELTNSEDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKEQLVEAKRELKGAKADAKVRKDEKFKKAVEAKKKALQRVEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKDYEF 758
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:zgc:173742 "zgc:173742" species:7955 "Danio rerio" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 ZFIN:ZDB-GENE-030131-6489 GO:GO:0005694 GO:GO:0003677 GO:GO:0006200 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 EMBL:CU424459 EMBL:CU459124 RefSeq:XP_002665372.2 RefSeq:XP_005170014.1 UniGene:Dr.82450 Ensembl:ENSDART00000006628 GeneID:334557 KEGG:dre:334557 OMA:GYCLLDH NextBio:20810455 Bgee:E7FGU8 Uniprot:E7FGU8) HSP 1 Score: 615.92 bits (1587), Expect = 0.000e+0 Identity = 318/563 (56.48%), Postives = 392/563 (69.63%), Query Frame = 0
Query: 352 WKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY---------------------SKSNQIRH------VKSFLKIKRGKGYY------------------EKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDE-DQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
W+WWEEEK ++G KWKFL+H+GP F P Y LP V FYYN + +KLS EEVA ++A+ ++HEYT KEVF NFFKDWRK MT EER +I +L KCDF E++ +K+ E RKN SKEEK KE N I DE+G CV+D+H E+IGNF+IEPPGLFRGR G + ++ K ++RH + S+ + +G Y E AR+LK+ ++ IR Y D KSK+M RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHITLH D + VEFDFLGKD IRY+N VPV KRVFKN++LFMENK+G DDLFDRLNT LN++L+SLM GLTAKVFRT+NAS TLQ QL+EL+ DNVP K+LSYNRANR VA+LCNHQRA PK+ D+SM NLQ KI +++E + A+K+LKQAKK K VV++KKKKA++R EQL K+E QA D+EENK IAL TSKLNYLDPRISVAW K +VP++K+YNKT RDKF WA++M D+VF
Sbjct: 173 WRWWEEEKYENGIKWKFLEHKGPYFPPAYQPLPDDVKFYYNGEPVKLSLPAEEVALYFAQMLDHEYTTKEVFRNNFFKDWRKEMTLEERQLIMDLKKCDFGELHAMHKEKVEARKNLSKEEKLVNKEANQKIVDEYGFCVLDHHRERIGNFKIEPPGLFRGRGDHPKQGMLKKRIRPEDVIINCSKESRIPEAPAGHKWKEVRHDKTVTWLASWTENVQGSCKYVMLNANSKLKGEKDWEKYEVARKLKTCVDAIRTQYQEDLKSKQMGTRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLHDALDDQKCVVEFDFLGKDCIRYYNKVPVTKRVFKNLKLFMENKQGGDDLFDRLNTASLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELSNMKDNVPEKLLSYNRANRAVAVLCNHQRAPPKSFDQSMANLQAKIDSRKEQLDLAKKELKQAKKEAKGSSDNKLLVVVEKKKKAVQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIYNKTLRDKFAWAVDMTELDFVF 735
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "Uncharacterized protein" species:9823 "Sus scrofa" [GO:0000228 "nuclear chromosome" evidence=IEA] [GO:0000932 "cytoplasmic mRNA processing body" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003682 "chromatin binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005654 "nucleoplasm" evidence=IEA] [GO:0005730 "nucleolus" evidence=IEA] [GO:0006260 "DNA replication" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0040016 "embryonic cleavage" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0043204 "perikaryon" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005654 GO:GO:0005730 GO:GO:0042493 GO:GO:0003677 GO:GO:0006260 GO:GO:0043204 GO:GO:0006200 GO:GO:0003682 GO:GO:0040016 GO:GO:0000932 GO:GO:0000228 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 OMA:EFDFPGK EMBL:CU062531 Ensembl:ENSSSCT00000029351 Uniprot:I3LHM3) HSP 1 Score: 618.231 bits (1593), Expect = 0.000e+0 Identity = 321/538 (59.67%), Postives = 390/538 (72.49%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRD 850
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G C++DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+
Sbjct: 283 EGIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVLKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQRE 820
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:top1mt "mitochondrial topoisomerase I" species:7955 "Danio rerio" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0016853 "isomerase activity" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 ZFIN:ZDB-GENE-040624-2 GO:GO:0005694 GO:GO:0003677 GO:GO:0006200 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 CTD:116447 HOVERGEN:HBG007988 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 eggNOG:NOG317235 EMBL:BC096851 EMBL:AY429655 RefSeq:NP_001001838.1 UniGene:Dr.79693 STRING:7955.ENSDARP00000026456 GeneID:415098 KEGG:dre:415098 NextBio:20818783 Uniprot:Q6T721) HSP 1 Score: 603.979 bits (1556), Expect = 0.000e+0 Identity = 307/559 (54.92%), Postives = 389/559 (69.59%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR------------------------------YLVGFMDRKYSKSNQIRHVKSFL----------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WEE K D KW L+H+GP FAPDY+ LP + FYY+ +++KLS TEE+A FYA+ ++HEYT KEVF +NFFKDWRK MT+EER +IT LSKCDF I+ Y+ + +EE+KN +KEEK+ K++ A + +EFG C++D H EKIGNF++EPPGLFRGR G ++ N + + S+L K+K K + YE AR LK ++ IR Y D+KS+EM+ RQR VA+YFIDKLALRAGNEKD++ ADTVGCCSLRVEHI LH DG D+ VEFDFLGKDSIRY+N VPVEK+VFKN++LF+++K EDDLFDR++T LN+ L M GLTAKVFRTFNAS TLQDQL +LT D V K+LSYNRANR VAILCNHQRAAPKT +KSMQ LQ+KI+ K+E E+A K+LK+AK+ K+ S +++KK+KA++R +QL KL+ Q D+EENK IALGTSKLNYLDPRI+VAW KK VPIEK++NKT R+KF WAI+M + F
Sbjct: 42 WEEGKSCDAVKWSSLEHKGPYFAPDYEPLPANICFYYDGQQVKLSPLTEEIATFYAKMLDHEYTTKEVFQKNFFKDWRKEMTKEERKLITTLSKCDFTHIHKYFVEKAEEKKNMTKEEKQVLKDEAARLMEEFGYCLLDGHREKIGNFKLEPPGLFRGRGEHPKMGRLKKRIQPEDVAINCSKDSKIPEPPAGHKWKRVQHDNTVTWLASWLENIPKRPKYIMLNPSSKLKGEKDWQKYETARRLKECVKSIRKRYMQDWKSREMKSRQRGVAIYFIDKLALRAGNEKDDESADTVGCCSLRVEHIRLHKHLDGLDHVVEFDFLGKDSIRYYNKVPVEKQVFKNLKLFIKHKDPEDDLFDRISTVNLNKALTESMSGLTAKVFRTFNASTTLQDQLNKLTSDDCTVEEKILSYNRANRAVAILCNHQRAAPKTFEKSMQLLQEKIQKKKEQIEEARKELKEAKQVDKDTPSDKSSKLVEKKQKAVQRLCDQLKKLQLQETDREENKVIALGTSKLNYLDPRITVAWCKKHQVPIEKIFNKTHREKFAWAIDMTDESFQF 600
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1MT "DNA topoisomerase I, mitochondrial" species:9606 "Homo sapiens" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IBA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005634 "nucleus" evidence=IDA] [GO:0005739 "mitochondrion" evidence=IDA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0006265 "DNA topological change" evidence=IBA] [GO:0042645 "mitochondrial nucleoid" evidence=IDA] [GO:0005730 "nucleolus" evidence=IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0031298 "replication fork protection complex" evidence=IBA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005524 GO:GO:0005694 GO:GO:0003677 GO:GO:0006260 GO:GO:0006200 DrugBank:DB01030 GO:GO:0042645 DrugBank:DB00762 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 EMBL:AF349031 EMBL:AF349018 EMBL:AF349019 EMBL:AF349020 EMBL:AF349021 EMBL:AF349022 EMBL:AF349023 EMBL:AF349024 EMBL:AF349025 EMBL:AF349026 EMBL:AF349027 EMBL:AF349028 EMBL:AF349029 EMBL:AF349030 EMBL:AF349017 EMBL:AK316380 EMBL:AC087793 EMBL:BC044646 EMBL:BC052285 EMBL:BC071914 RefSeq:NP_001245375.1 RefSeq:NP_001245376.1 RefSeq:NP_443195.1 UniGene:Hs.528574 ProteinModelPortal:Q969P6 SMR:Q969P6 BioGrid:125510 STRING:9606.ENSP00000328835 ChEMBL:CHEMBL2362989 PhosphoSite:Q969P6 DMDM:20140694 PaxDb:Q969P6 PRIDE:Q969P6 Ensembl:ENST00000329245 Ensembl:ENST00000519148 Ensembl:ENST00000521193 Ensembl:ENST00000523676 GeneID:116447 KEGG:hsa:116447 UCSC:uc003yxz.4 CTD:116447 GeneCards:GC08M144391 HGNC:HGNC:29787 HPA:HPA001915 HPA:HPA021542 MIM:606387 neXtProt:NX_Q969P6 PharmGKB:PA134922772 eggNOG:COG3569 HOGENOM:HOG000105469 HOVERGEN:HBG007988 InParanoid:Q969P6 KO:K03163 OMA:VINCSRD OrthoDB:EOG7CVPX5 PhylomeDB:Q969P6 TreeFam:TF105281 GenomeRNAi:116447 NextBio:79927 PRO:PR:Q969P6 ArrayExpress:Q969P6 Bgee:Q969P6 CleanEx:HS_TOP1MT Genevestigator:Q969P6 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 Uniprot:Q969P6) HSP 1 Score: 598.201 bits (1541), Expect = 0.000e+0 Identity = 303/560 (54.11%), Postives = 385/560 (68.75%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHVK----SFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEK-DEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WE+EK +DG KW+ L+H+GP FAP Y+ LP GV F+Y + ++LS EEVA FY R ++HEYT KEVF +NFF DWRK M EER++I +L KCDF EI+ Y+ + RK S+EEK+ KE+ +Q EFG C++D H EKIGNF+IEPPGLFRGR +G + R+ S N I+++ S LK + +E AR L+ +++IR Y D+KS+EM+ RQR+VALYFIDKLALRAGNEK D + ADTVGCCSLRVEH+ LH DG + VEFDFLGKD IRY+N VPVEK V+KN+QLFMENK DDLFDRL TT LN++L LM GLTAKVFRT+NAS TLQ+QL LT A+D++ AK+LSYNRANR VAILCNHQRA P T +KSMQNLQ KI+AK+E +A +L++A+ +K G + V++KK++ LE+ EQL +L QA DKEENK +ALGTSKLNYLDPRIS+AW K+F VP+EK+Y+KTQR++F WA+ MAG D+ F
Sbjct: 42 WEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:top1beta "Topoisomerase I beta" species:31033 "Takifugu rubripes" [GO:0003917 "DNA topoisomerase type I activity" evidence=IBA] [GO:0005730 "nucleolus" evidence=IBA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0006265 "DNA topological change" evidence=IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0031298 "replication fork protection complex" evidence=IBA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0007059 GO:GO:0005730 GO:GO:0003677 GO:GO:0006260 GO:GO:0006200 GO:GO:0006338 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 HOGENOM:HOG000105469 KO:K03163 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 EMBL:AL035358 RefSeq:XP_003973717.1 ProteinModelPortal:Q90WS1 SMR:Q90WS1 STRING:31033.ENSTRUP00000031263 GeneID:101069232 KEGG:tru:101069232 CTD:101069232 InParanoid:Q90WS1 Uniprot:Q90WS1) HSP 1 Score: 603.594 bits (1555), Expect = 0.000e+0 Identity = 321/553 (58.05%), Postives = 396/553 (71.61%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKY------SKSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DG KWKFL+H+GP+FAP Y+ LP V FYY+ K L + EEVA F+A+ ++HEYT K+VF +NFFKDWRK MT EE+ IT+L KCDF E++ Y+K SE RK +KEEK KE+N + ++G C++DNH E+I NFRIEPPGLFRGR +G + D KY +K ++RH +K + +IK K + YE AR LK +++IR+ Y D+KSKEMR+RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI L+ DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK +DDLFDRLNT+ILN++L LM GLTAKVFRT+NAS TLQ QL+ELT A++N+PAK+LSYNRANR VAILCNHQRA PKT +KSMQNLQ KI AK+ A+++LK AK K K ++ KKKA++R +QL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK+ +P+EK+YNKTQR+KF WAI+MA DY F
Sbjct: 201 DGVKWKFLEHKGPVFAPPYEPLPSNVKFYYDGKAFMLRAGAEEVATFFAKMLDHEYTTKDVFRKNFFKDWRKEMTSEEKAKITDLKKCDFSEMHQYFKAQSEARKAMTKEEKLKIKEENERLLQQYGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPQDIIINCSKDSKYPEPPPGTKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQAQLKELTSAEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKAQLSAAKRELKSAKADAKVRRDEKSKKAVEAKKKAVQRIDDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPVEKIYNKTQREKFAWAIDMAEDDYEF 753
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1MT "DNA topoisomerase I, mitochondrial" species:9598 "Pan troglodytes" [GO:0003917 "DNA topoisomerase type I activity" evidence=IBA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0006265 "DNA topological change" evidence=IBA] [GO:0042645 "mitochondrial nucleoid" evidence=IBA] [GO:0005730 "nucleolus" evidence=IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0031298 "replication fork protection complex" evidence=IBA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005524 GO:GO:0005694 GO:GO:0003677 GO:GO:0006260 GO:GO:0006200 GO:GO:0042645 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 CTD:116447 eggNOG:COG3569 HOGENOM:HOG000105469 KO:K03163 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 EMBL:EF421830 RefSeq:NP_001106268.1 UniGene:Ptr.6282 ProteinModelPortal:A9Q1D5 SMR:A9Q1D5 STRING:9598.ENSPTRP00000035312 GeneID:472883 KEGG:ptr:472883 InParanoid:A9Q1D5 NextBio:20849513 Uniprot:A9Q1D5) HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0 Identity = 302/560 (53.93%), Postives = 384/560 (68.57%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHVK----SFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEK-DEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WE+EK +DG KW+ L+H+GP FAP Y+ LP GV F+Y K ++LS EEVA FY R + HEYT KEVF +NFF DWRK M EER++I +L KCDF EI+ Y+ + RK S+EEK+ KE+ +Q EFG C++D H EKIGNF+IEPPGLFRGR +G + R+ S N I+++ S LK + +E AR L+ +++IR Y D+KS+EM+ RQR+VALYFIDKLALRAGNEK D + ADTVGCCSLRVEH+ LH DG + VEFDFLGKD IRY+N VPVEK V+KN+QLFME+K D+LFDRL TT LN++L LM GLTAKVFRT+NAS TLQ+QL LT A+D++ AK+LSYNRANR VAILCNHQRA P T +KSMQNLQ KI+AK+E +A +L++A+ +K G + V++KK++ LE+ EQL +L QA DKEENK +ALGTSKLNYLDPRIS+AW K+F VP+EK+Y+KTQR++F WA+ MAG D+ F
Sbjct: 42 WEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGKPVRLSVAAEEVATFYGRMLGHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQREFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRIMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMESKGPRDNLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:Top1 "Topoisomerase 1" species:7227 "Drosophila melanogaster" [GO:0006265 "DNA topological change" evidence=IDA] [GO:0005634 "nucleus" evidence=IDA] [GO:0003917 "DNA topoisomerase type I activity" evidence=ISS;NAS;IDA] [GO:0005703 "polytene chromosome puff" evidence=IDA] [GO:0005730 "nucleolus" evidence=IDA] [GO:0005719 "nuclear euchromatin" evidence=IDA] [GO:0007275 "multicellular organismal development" evidence=IMP] [GO:0003916 "DNA topoisomerase activity" evidence=IDA] [GO:0005665 "DNA-directed RNA polymerase II, core complex" evidence=IDA] [GO:0030261 "chromosome condensation" evidence=IMP] [GO:0002168 "instar larval development" evidence=IMP] [GO:0048477 "oogenesis" evidence=IMP] [GO:0007059 "chromosome segregation" evidence=IMP] [GO:0005737 "cytoplasm" evidence=IDA] [GO:0009790 "embryo development" evidence=IMP] [GO:0008283 "cell proliferation" evidence=IMP] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005875 "microtubule associated complex" evidence=IDA] [GO:0006468 "protein phosphorylation" evidence=IMP] [GO:0005700 "polytene chromosome" evidence=IDA] [GO:0004672 "protein kinase activity" evidence=IDA] [GO:0031298 "replication fork protection complex" evidence=IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0006260 "DNA replication" evidence=IBA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005524 GO:GO:0005737 GO:GO:0005875 GO:GO:0007059 GO:GO:0005730 GO:GO:0003677 GO:GO:0008283 GO:GO:0006260 EMBL:AE014298 GO:GO:0006200 GO:GO:0048477 GO:GO:0004672 GO:GO:0006338 GO:GO:0009790 GO:GO:0005719 GO:GO:0030261 GO:GO:0002168 GO:GO:0005703 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 KO:K03163 OrthoDB:EOG7CVPX5 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 CTD:7150 EMBL:M74557 EMBL:U80064 PIR:S35521 RefSeq:NP_001014742.1 RefSeq:NP_511161.2 UniGene:Dm.2912 ProteinModelPortal:P30189 SMR:P30189 BioGrid:58813 IntAct:P30189 MINT:MINT-748832 PaxDb:P30189 PRIDE:P30189 GeneID:32458 KEGG:dme:Dmel_CG6146 FlyBase:FBgn0004924 InParanoid:P30189 ChiTaRS:TOP1 GenomeRNAi:32458 NextBio:778562 PRO:PR:P30189 Bgee:P30189 Uniprot:P30189) HSP 1 Score: 595.504 bits (1534), Expect = 0.000e+0 Identity = 311/552 (56.34%), Postives = 383/552 (69.38%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH------VKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DG KW L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y KEVFN NFFKD+RK MT ER+II + KC+F+E+ Y++ SE+RK SKEEK +K +N A+ EFG C+ID H EKIGNFR+EPPGLFRGR +G + R+ S+ ++RH + S+++ +G KG YE AR L I+KIR Y ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH +GK+ V FDF GKDSIRY+N V VEKRVFKN++LFME+K+ DDLFDRLNT +LNE+L LM+GLTAKVFRT+NAS TLQ QL+ LT+ VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E + +KK K LER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA +Y F
Sbjct: 436 DGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 972
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592776306|gb|GAXK01178262.1| (TSA: Calanus finmarchicus comp15061_c1_seq1 transcribed RNA sequence) HSP 1 Score: 619.002 bits (1595), Expect = 0.000e+0 Identity = 359/548 (65.51%), Postives = 414/548 (75.55%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYXXXXXXXXXXXXXXXXXXXXXXXAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---------------------------YLVGFMDRKYSK-----------------SNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDXXXXXXXXXXXXXXXXXXXXXXYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGAD 862
G KWKFLQH GP FAPDYD LP+ V F+Y K ++L+ ETEE A FY R ++H+YT KEVFN+NFFKDWRKVMT +E+DII +LSKCDF EIN ++KKVSEERKNRSKEEKKAEKE N AI +FG C +D H EKIGNFR EPP LFRGR V RK+ K QI+++ S LK ++ YEKAR+LK +I KIRDDY D KSKEMRVRQR+VALYFID+LALRAGNEKDEDQADTVGCCSLRVEHI LH DGK++ VEFDFLGKDSIRYHN VEK+V+KNV+LFMENK+ DDLFDRLNT++LN+YLNSLM GLTAKVFRT+NASFTLQ+QL+E+T+ +DNV AKMLSYNRANR VA+LCNHQRA PKTH+KSM NL KI+AK++A ++AEK LK AKKAYKN GS +EK +KKKK LER +EQL+KLE Q DK+ENKTIALGTSKLNYLDPRISVAW KK DVPIEKVYNKTQR+KFRWAI+M D
Sbjct: 1523 GVKWKFLQHLGPQFAPDYDPLPEHVRFWYEGKTLRLTEETEECATFYGRMLDHDYTTKEVFNKNFFKDWRKVMTEKEKDIIRDLSKCDFSEINEHFKKVSEERKNRSKEEKKAEKEVNEAIIADFGFCTMDGHQEKIGNFRTEPPSLFRGRGEHPKQGMIKRRIMPEDVIINCSKDSEIPVPPKGRKWKKVQHDNTVTWLASWTENIQGQIKYIMLNPSSRLKGEKDWQKYEKARKLKVEIHKIRDDYMEDMKSKEMRVRQRAVALYFIDRLALRAGNEKDEDQADTVGCCSLRVEHIELHEQLDGKEFVVEFDFLGKDSIRYHNTTSVEKKVYKNVKLFMENKKDGDDLFDRLNTSVLNQYLNSLMDGLTAKVFRTYNASFTLQEQLDEMTDPNDNVSAKMLSYNRANRAVAVLCNHQRAVPKTHEKSMDNLYGKIEAKQDAIKEAEKGLKHAKKAYKNNGSVAEKANAEKKKKTLERLLEQLEKLEIQKTDKDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKVYNKTQREKFRWAIDMITND 3166
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592810838|gb|GAXK01143730.1| (TSA: Calanus finmarchicus comp3642341_c0_seq1 transcribed RNA sequence) HSP 1 Score: 35.8094 bits (81), Expect = 5.175e-1 Identity = 23/51 (45.10%), Postives = 37/51 (72.55%), Query Frame = 0
Query: 778 TSEKVVMDKKKKALERTVEQL-DKLETQAVDKEENKTIALGTSKLNYLDPR 827
++EK +M++K K LE E L +KLET+ ++KEE+K+++ +LN LDPR
Sbjct: 560 SNEKEIMEEKLKDLETENEILREKLETKEIEKEESKSLS---EELNILDPR 703
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938100|gb|GAXK01020453.1| (TSA: Calanus finmarchicus comp12086_c0_seq4 transcribed RNA sequence) HSP 1 Score: 35.039 bits (79), Expect = 1.346e+0 Identity = 24/87 (27.59%), Postives = 44/87 (50.57%), Query Frame = 0
Query: 780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKTQRDKFRWAIEMAGADY 863
E+ +++++ L + E+ +LETQ + N A G+S ++PRI + W + V ++ ++QR R EMAG D+
Sbjct: 2196 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSR-SVTGPGMFERSQRSMDR---EMAGGDF 2444
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938102|gb|GAXK01020451.1| (TSA: Calanus finmarchicus comp12086_c0_seq2 transcribed RNA sequence) HSP 1 Score: 35.039 bits (79), Expect = 1.361e+0 Identity = 24/87 (27.59%), Postives = 44/87 (50.57%), Query Frame = 0
Query: 780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKTQRDKFRWAIEMAGADY 863
E+ +++++ L + E+ +LETQ + N A G+S ++PRI + W + V ++ ++QR R EMAG D+
Sbjct: 2615 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSR-SVTGPGMFERSQRSMDR---EMAGGDF 2863
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938101|gb|GAXK01020452.1| (TSA: Calanus finmarchicus comp12086_c0_seq3 transcribed RNA sequence) HSP 1 Score: 33.113 bits (74), Expect = 5.935e+0 Identity = 23/92 (25.00%), Postives = 43/92 (46.74%), Query Frame = 0
Query: 780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKT-----QRDKFRWAIEMAGADY 863
E+ +++++ L + E+ +LETQ + N A G+S ++PRI + W + V++ T +R + EMAG D+
Sbjct: 2196 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSRRATSSTNVHSVTGPGMFERSQRSMDREMAGGDF 2471
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938103|gb|GAXK01020450.1| (TSA: Calanus finmarchicus comp12086_c0_seq1 transcribed RNA sequence) HSP 1 Score: 33.113 bits (74), Expect = 5.996e+0 Identity = 23/92 (25.00%), Postives = 43/92 (46.74%), Query Frame = 0
Query: 780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKT-----QRDKFRWAIEMAGADY 863
E+ +++++ L + E+ +LETQ + N A G+S ++PRI + W + V++ T +R + EMAG D+
Sbjct: 2615 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSRRATSSTNVHSVTGPGMFERSQRSMDREMAGGDF 2890
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592912910|gb|GAXK01045465.1| (TSA: Calanus finmarchicus comp416754_c0_seq1 transcribed RNA sequence) HSP 1 Score: 31.9574 bits (71), Expect = 7.930e+0 Identity = 15/45 (33.33%), Postives = 25/45 (55.56%), Query Frame = 0
Query: 773 KNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALG 817
K G +E ++MDK KKA+E+T + +KL + + + LG
Sbjct: 617 KTAGERNEALMMDKAKKAMEKTTDPGEKLRCYCLSRGATGILGLG 751
BLAST of EMLSAG00000000293 vs. L. salmonis peptides
Match: EMLSAP00000000293 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1044:15439:19815:-1 gene:EMLSAG00000000293 transcript:EMLSAT00000000293 description:"maker-LSalAtl2s1044-snap-gene-0.46") HSP 1 Score: 1739.93 bits (4505), Expect = 0.000e+0 Identity = 865/865 (100.00%), Postives = 865/865 (100.00%), Query Frame = 0
Query: 1 MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF
Sbjct: 1 MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|12644118|sp|P11387.2|TOP1_HUMAN (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 330/553 (59.67%), Postives = 401/553 (72.51%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K +E RK SKEEK KE+N + E+G C++DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 213 EGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|38503303|sp|Q7YR26.1|TOP1_CHLAE (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 638.262 bits (1645), Expect = 0.000e+0 Identity = 330/552 (59.78%), Postives = 399/552 (72.28%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K +E RK SKEEK KE+N + E+G C++DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPDSVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|51316560|sp|Q9WUL0.1|TOP1_RAT (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0 Identity = 330/552 (59.78%), Postives = 398/552 (72.10%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A KDLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|586107|sp|Q07050.1|TOP1_CRIGR (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 632.484 bits (1630), Expect = 0.000e+0 Identity = 328/552 (59.42%), Postives = 398/552 (72.10%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E+++ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTV CCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNVITNLSKCDFTQMSQYFKDQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|158518540|sp|Q04750.2|TOP1_MOUSE (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 631.713 bits (1628), Expect = 0.000e+0 Identity = 328/552 (59.42%), Postives = 397/552 (71.92%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|1174739|sp|P41512.1|TOP1_XENLA (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 609.372 bits (1570), Expect = 0.000e+0 Identity = 312/537 (58.10%), Postives = 385/537 (71.69%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRG------------RYLVGFMDRKYSKSNQI------------RH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQR 849
DG KWKFL+H+GP+FAP Y+ +P V FYY+ +KLS + EEVA F+A+ ++HEYT K++F +NFFKDW+K MT +ER++ITNLSKCDF ++ Y+K+ SE RKN +KEEK K +N + E+G C++DNH E+I NFRIEPPGLFRG R + + SK ++I RH +K + +IK K + YE AR LK +EKIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI L DG+++ VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ +DDLFDRLNT+ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT +DDNVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A ++ K AK K K +++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK+ VPIEK+YNKTQR
Sbjct: 269 DGIKWKFLEHKGPVFAPPYEPVPDNVKFYYDGNLVKLSPKAEEVATFFAKMLDHEYTTKDIFRKNFFKDWKKEMTTDERNLITNLSKCDFNAMSLYFKEQSEARKNMTKEEKLKIKAENERLLQEYGYCIMDNHKERIANFRIEPPGLFRGRGDHPKMGKLKKRIMPEDIIINCSKDSKIPVAPAGHKWKEVRHDGKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKMCVEKIRNTYKEDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLDELTNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLADARREFKSAKADAKVRRDEKTKKLVESKKKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQR 805
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|20140694|sp|Q969P6.1|TOP1M_HUMAN (RecName: Full=DNA topoisomerase I, mitochondrial; Short=TOP1mt; Flags: Precursor) HSP 1 Score: 598.201 bits (1541), Expect = 0.000e+0 Identity = 303/560 (54.11%), Postives = 385/560 (68.75%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHVK----SFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEK-DEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WE+EK +DG KW+ L+H+GP FAP Y+ LP GV F+Y + ++LS EEVA FY R ++HEYT KEVF +NFF DWRK M EER++I +L KCDF EI+ Y+ + RK S+EEK+ KE+ +Q EFG C++D H EKIGNF+IEPPGLFRGR +G + R+ S N I+++ S LK + +E AR L+ +++IR Y D+KS+EM+ RQR+VALYFIDKLALRAGNEK D + ADTVGCCSLRVEH+ LH DG + VEFDFLGKD IRY+N VPVEK V+KN+QLFMENK DDLFDRL TT LN++L LM GLTAKVFRT+NAS TLQ+QL LT A+D++ AK+LSYNRANR VAILCNHQRA P T +KSMQNLQ KI+AK+E +A +L++A+ +K G + V++KK++ LE+ EQL +L QA DKEENK +ALGTSKLNYLDPRIS+AW K+F VP+EK+Y+KTQR++F WA+ MAG D+ F
Sbjct: 42 WEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|267147|sp|P30189.1|TOP1_DROME (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 595.504 bits (1534), Expect = 0.000e+0 Identity = 311/552 (56.34%), Postives = 383/552 (69.38%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH------VKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DG KW L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y KEVFN NFFKD+RK MT ER+II + KC+F+E+ Y++ SE+RK SKEEK +K +N A+ EFG C+ID H EKIGNFR+EPPGLFRGR +G + R+ S+ ++RH + S+++ +G KG YE AR L I+KIR Y ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH +GK+ V FDF GKDSIRY+N V VEKRVFKN++LFME+K+ DDLFDRLNT +LNE+L LM+GLTAKVFRT+NAS TLQ QL+ LT+ VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E + +KK K LER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA +Y F
Sbjct: 436 DGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 972
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|259533973|sp|A9Q1D5.1|TOP1M_PANTR (RecName: Full=DNA topoisomerase I, mitochondrial; Short=TOP1mt; Flags: Precursor) HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0 Identity = 302/560 (53.93%), Postives = 384/560 (68.57%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHVK----SFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEK-DEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WE+EK +DG KW+ L+H+GP FAP Y+ LP GV F+Y K ++LS EEVA FY R + HEYT KEVF +NFF DWRK M EER++I +L KCDF EI+ Y+ + RK S+EEK+ KE+ +Q EFG C++D H EKIGNF+IEPPGLFRGR +G + R+ S N I+++ S LK + +E AR L+ +++IR Y D+KS+EM+ RQR+VALYFIDKLALRAGNEK D + ADTVGCCSLRVEH+ LH DG + VEFDFLGKD IRY+N VPVEK V+KN+QLFME+K D+LFDRL TT LN++L LM GLTAKVFRT+NAS TLQ+QL LT A+D++ AK+LSYNRANR VAILCNHQRA P T +KSMQNLQ KI+AK+E +A +L++A+ +K G + V++KK++ LE+ EQL +L QA DKEENK +ALGTSKLNYLDPRIS+AW K+F VP+EK+Y+KTQR++F WA+ MAG D+ F
Sbjct: 42 WEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGKPVRLSVAAEEVATFYGRMLGHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQREFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRIMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMESKGPRDNLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|74957937|sp|O17966.1|TOP1_CAEEL (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I; Short=topoI) HSP 1 Score: 547.74 bits (1410), Expect = 0.000e+0 Identity = 313/575 (54.43%), Postives = 381/575 (66.26%), Query Frame = 0
Query: 350 EVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYL---VGFMDRKYS---------------------KSNQIRH----------VKSFL------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQA-DTVGCCSLRVEHITLHTV-------KDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGA---DYVF 865
++W+WW+EEK G KW LQH GPLFAP Y LP VHF Y +KMKL+ ETEE+A FYA ++HEY+ KE FN+NF KDWRKVMT EER+ I +L KCDFR I+ Y K+ E RK +KEEK KE+ A +GI +ID H +K+ NFRIEPPG+FRGR +G + ++ K ++RH +S L KIK K + YE AR LK KI IR+ YT DFKSKEMRVRQR+ ALYFIDKLALRAGNEKD D+A DTVGCCSLRVEHI L K K++ VEFDFLGKDSIRY N V VEKRV+KN+++FME K DDLFDRL+T LN++L SLM GLT KVFRT+NAS TLQ+QL +LT DNV AK+LSYNRANR+VAILCNHQRA K D+SMQ L+ KIK K++ ++AE LK A+ A K +K +K +R EQL KL+ DK+ENK IALGTSKLNY+DPRI+VAW KKF+VP+EKV+ KT R+KFRWAI+M + +YVF
Sbjct: 243 DIWEWWKEEKKPAGVKWNSLQHCGPLFAPPYIPLPSHVHFKYGGEKMKLTLETEEIAQFYAGVLDHEYSTKEAFNKNFMKDWRKVMTVEERERIHDLKKCDFRAIDAYQKEQREIRKAMTKEEKLKIKEEKEAEVKIYGIAIIDGHRQKVANFRIEPPGVFRGRGGHPKMGLIKKRIMPEDVIINCGKDTEIPKPPPGHKWKEVRHDNTVTWLCSWTESVLGQNKYIMLNPSSKIKGEKDFEKYETARRLKKKIGGIRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFDFLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAALKSARGAEK-----------EKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAIDMTNSSDEEYVF 806
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: gb|EFA03005.1| (DNA topoisomerase 1-like Protein [Tribolium castaneum]) HSP 1 Score: 715.301 bits (1845), Expect = 0.000e+0 Identity = 382/672 (56.85%), Postives = 481/672 (71.58%), Query Frame = 0
Query: 260 ENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDE-DSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNH-----------------KVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
E+ +VK ++DS++D+PL+ + ++ K + E D EDD+PL+ RKKPK +K E+ E KK +S + + +K E SP K G +KK+E+ EVWKWWEEEK DDG KWKFL+H+GP+FAP Y+ LP V FYY+ K+MKL+ E EEVA FY++ ++H+YT KEVFN NFFKDWRKVM+ ER +I +L KC+F+ ++ YY ++E+ +NR+KEEK+A KEKN A+ E+G C ID H EKIGNF+IEPPGLFRGR +G + R+ + NQ++++ S LK ++ YE AR L I+KIR++Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI+LH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFME+K DDLFDRLNT I+N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT ADD+V K+L+YNRANR VAILCNHQR+ PK H+KSM+ L++KI AK+EA + AE+ +K A K K+ GS EK V DKKKK L+R EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK+ VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 273 EDSTADVKQEEDSDEDLPLSARMEHTSVKRKIESDDEDDMPLNARKKPKKEKKEKSEKKKKKRSVEDDEEEWDRPVKKEKIKKEKDSIKTENESPKKGGRKKKEEEPQEVWKWWEEEKKDDGKKWKFLEHKGPVFAPPYEPLPDHVKFYYDGKEMKLTPEAEEVASFYSKMLDHDYTTKEVFNNNFFKDWRKVMSESERKVIKDLKKCNFKSMHAYYMDLAEKNRNRTKEEKQALKEKNEALIKEYGFCNIDGHKEKIGNFKIEPPGLFRGRGEHPKMGMLKRRVEAEDIIINCSQDSKIPEPPPGHKWKEVRHDDNVTWLASWTENVQNQVKYIMLNPSSKLKGEKDWQKYETARRLHKCIDKIREEYKDDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHISLHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMEHKSPGDDLFDRLNTAIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNADDSVAEKILAYNRANRAVAILCNHQRSVPKGHEKSMEKLKEKIDAKKEAIKDAERQVKDAAKDAKH-GSVKEKTVYDKKKKMLQRLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQRDKFRWAIDMAGPDYVF 943
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: XP_396203.4 (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Apis mellifera]) HSP 1 Score: 711.064 bits (1834), Expect = 0.000e+0 Identity = 383/661 (57.94%), Postives = 470/661 (71.10%), Query Frame = 0
Query: 266 VKVQDDSEDDIPLAKKS--KNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGR-----------KKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLVGFM-DRKYSKSN------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+K +++S++D+PL+ +S ++S D + E+DVPLS RKK K + + +K + + +++ + P K G R KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP V+FYYN K+MKLS +TEEVA FYAR ++H+YT K FN NFF DWR+VMT ER I +LSKC+F+EI+ Y+ + SEERK +KEEK+ KEKN IQ E+G C+ID H EKIGNF+IEPPGLFRGR L+ D K +IRH VK + K+K K + YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT DD K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A AE +K AK+ K+ GS EKV +KKKKAL+R EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 370 IKTEEESDEDVPLSARSMAPTSIKRSLDSEEEEDVPLSARKKSKKSDTKTKKKKRKYEDDEDEDEIEQK---PKKKGARTSKGENSSPRKKKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVNFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERTKIVDLSKCNFKEIHAYFIQKSEERKAMTKEEKQKIKEKNEEIQKEYGYCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSNIPKPPPGHKWKEIRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYEIARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAINDAELAVKDAKRDAKH-GSVKEKVTYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1026
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EEB15907.1 (DNA topoisomerase, putative [Pediculus humanus corporis]) HSP 1 Score: 694.886 bits (1792), Expect = 0.000e+0 Identity = 376/646 (58.20%), Postives = 461/646 (71.36%), Query Frame = 0
Query: 269 QDDSEDDIPLAKKSKNKKRKSR-DEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKS------NQIRH------VKSFLKIKRGKGYY------------------EKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
Q+DS+DD KK+K KKRKS+ D DSEDD KP KK + + K+ K K SP K KK+E++ +VWKWWEEEK +DG KWKFL+H+GPLFAP Y+RLPK V F+Y+ K++ LS E EEVA FYA+ + H+YT KE FN NFF DWRKVMT +ER +IT+LSKC+F+ + Y+++ SEERK SKEEKK K++N AIQ E+G C ID H EKIGNFRIEPPGLFRGR +G + D K K +++H + S+ + +G Y E AR+L KI+KIR+ Y D+KSKEM++RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ L+ +GK+ V FDFLGKDSIRY+N VPVEKRVFKN+ LF ENK+ +DDLFDRLNTT+LN++LN LM+GLTAKVFRT+NAS+TLQ+QL+ELT DD V K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL+ KI+AKRE + +K++K AK +NG S +E KKKK L+R EQL KLE Q DKEENKTIALGTSKLNYLDPRISVAW KK++VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 340 QEDSDDDFKPGKKTKGKKRKSKGDSDSEDDF------KPAAKKPSKTVIKKEVK--------KETTTSPKKV---KKEEEQQDVWKWWEEEKREDGKKWKFLEHKGPLFAPLYERLPKSVKFFYDGKEISLSEEAEEVATFYAKMLTHDYTTKEKFNTNFFNDWRKVMTDKERKVITDLSKCNFKPMALYFQEKSEERKAMSKEEKKVIKDQNDAIQKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKKRVLPEDVIINCSKDSKIPKPPDGHKWKKVQHDPSVTWLASWTENVQGNVKYVMLNPSSKLKGEKDMVKYETARKLAKKIDKIREQYQADWKSKEMKIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVELYPELNGKENVVVFDFLGKDSIRYYNEVPVEKRVFKNLLLFKENKQPQDDLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASWTLQEQLKELTNPDDTVAEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKAKIEAKREQINEIKKEVKNAK---RNGDSGTEA----KKKKQLDRLKEQLLKLEVQETDKEENKTIALGTSKLNYLDPRISVAWCKKYNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 961
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: XP_016770482.1 (PREDICTED: DNA topoisomerase 1 isoform X2 [Apis mellifera]) HSP 1 Score: 666.381 bits (1718), Expect = 0.000e+0 Identity = 350/559 (62.61%), Postives = 416/559 (74.42%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLF--RGRYL-VGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WEEEK +DGTKW FL+H+GP+FAP Y+ LP V+FYYN K+MKLS +TEEVA FYAR ++H+YT K FN NFF DWR+VMT ER I +LSKC+F+EI+ Y+ + SEERK +KEEK+ KEKN IQ E+G C+ID H EKIGNF+IEPPGLF RG + +G + ++ K +IRH VK + K+K K + YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT DD K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A AE +K AK+ K+ GS EKV +KKKKAL+R EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 17 WEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVNFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERTKIVDLSKCNFKEIHAYFIQKSEERKAMTKEEKQKIKEKNEEIQKEYGYCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSNIPKPPPGHKWKEIRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYEIARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAINDAELAVKDAKRDAKH-GSVKEKVTYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 574
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EGK96321.1 (AGAP004078-PB [Anopheles gambiae str. PEST]) HSP 1 Score: 652.899 bits (1683), Expect = 0.000e+0 Identity = 332/559 (59.39%), Postives = 402/559 (71.91%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WEEEK DDG KWK+L+H+GP+FAP YD LP V F Y+ K+MKLS + EEVAGFYAR +EH+YT K+ FN NFFKDWRK MT ER+ IT+L KC+FR + Y+ +++E+ +NRSKEEK A K N + E+GICVID H EKIGNF+IEPPGLFRGR +G + R+ + ++RH VK + K+K K + YE AR L I+KIRD Y ++KSKEMR+RQR+VA+YFIDKLALRAGNEKD+DQADTVGCCSLR EHI LH +GK+ V FDFLGKDSIRY+N V VEKRVFKN++LF ENK+ DDLFDRLNT+++NEYL LM GLTAKVFRTFNAS+TLQ QLEELT+ + +VP K+L+YNRANR VAILCNHQRA PKTH+KSM NL++KI+ KRE E+ +K+ K KK+ + + DKK K LER EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KKF VPIEK++NKTQRDKFRWAI+MA +YVF
Sbjct: 28 WEEEKRDDGVKWKYLEHKGPVFAPPYDPLPSHVKFMYDGKEMKLSQDAEEVAGFYARMLEHDYTSKQAFNDNFFKDWRKTMTPHERERITDLEKCNFRPMAAYFAEIAEQNRNRSKEEKAALKAANEQLTKEYGICVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGLVKRRVMPEDVIINCSQDSKIPSPPPGRRWKEVRHDNTVSWLASWVENVQGQVKYIMLNPSSKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVAMYFIDKLALRAGNEKDDDQADTVGCCSLRYEHIALHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMGNLKEKIRVKREQVEQCQKEFKDLKKS-----NVRDPSAFDKKSKQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAIDMADENYVF 581
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EAA05377.5 (AGAP004078-PA [Anopheles gambiae str. PEST]) HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0 Identity = 327/553 (59.13%), Postives = 397/553 (71.79%), Query Frame = 0
Query: 361 DDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DDG KWK+L+H+GP+FAP YD LP V F Y+ K+MKLS + EEVAGFYAR +EH+YT K+ FN NFFKDWRK MT ER+ IT+L KC+FR + Y+ +++E+ +NRSKEEK A K N + E+GICVID H EKIGNF+IEPPGLFRGR +G + R+ + ++RH VK + K+K K + YE AR L I+KIRD Y ++KSKEMR+RQR+VA+YFIDKLALRAGNEKD+DQADTVGCCSLR EHI LH +GK+ V FDFLGKDSIRY+N V VEKRVFKN++LF ENK+ DDLFDRLNT+++NEYL LM GLTAKVFRTFNAS+TLQ QLEELT+ + +VP K+L+YNRANR VAILCNHQRA PKTH+KSM NL++KI+ KRE E+ +K+ K KK+ + + DKK K LER EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KKF VPIEK++NKTQRDKFRWAI+MA +YVF
Sbjct: 541 DDGVKWKYLEHKGPVFAPPYDPLPSHVKFMYDGKEMKLSQDAEEVAGFYARMLEHDYTSKQAFNDNFFKDWRKTMTPHERERITDLEKCNFRPMAAYFAEIAEQNRNRSKEEKAALKAANEQLTKEYGICVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGLVKRRVMPEDVIINCSQDSKIPSPPPGRRWKEVRHDNTVSWLASWVENVQGQVKYIMLNPSSKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVAMYFIDKLALRAGNEKDDDQADTVGCCSLRYEHIALHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMGNLKEKIRVKREQVEQCQKEFKDLKKS-----NVRDPSAFDKKSKQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAIDMADENYVF 1088
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EFX74248.1 (hypothetical protein DAPPUDRAFT_109061 [Daphnia pulex]) HSP 1 Score: 635.565 bits (1638), Expect = 0.000e+0 Identity = 325/522 (62.26%), Postives = 394/522 (75.48%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSNQIRHVKSFLKIKRGKGY-YEKARE------LKSKIEKIRD-DYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WEEEK +DG KWK L+H+GP+FA Y+ LP V F YN ++MKLS+ EEV FYA ++H+Y K+VFN+NFFKDWRK MT E++IIT+L KCDF + TY+K SEERKNR+KEEK K +N + E+G C+ID H ++IGNF+IEPPGLFRGR +G + R+ + I + K G+ +++ R L S E ++ Y D+KSKEM++RQRSVALYFIDKLALRAGNEKDEDQADTVG CSLRVEHI+LH K+GK V FDFLGKDSIRY+N VPVEKRVFKN+Q+FMENK+ DDLFDRLNTTI+N++LN LM+GLTAKVFRTFNAS TLQ+QL+ELT+ +V K+L+YNRANR VAILCNHQRA PKT KSM+NLQ KI AKREA E AEK K KK K GS + K+ KK+K +E+ EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK DVPIEK+YNKTQR+KF+WAI+MAG ++VF
Sbjct: 22 WEEEKHEDGVKWKSLEHKGPVFATQYEPLPGNVKFKYNGQEMKLSTAAEEVGSFYAAMLDHDYVTKDVFNKNFFKDWRKFMTHSEKEIITDLKKCDFTYMLTYFKAKSEERKNRTKEEKLQLKTENEEMVKEYGWCIIDGHKQRIGNFKIEPPGLFRGRGDHPKMGMVKRRVMPEDVIINCTKGTAPKPPPGHKWKEVRSDNTVTWLASWTENVQGQTYKEDWKSKEMKIRQRSVALYFIDKLALRAGNEKDEDQADTVGACSLRVEHISLHEQKEGKQCVVVFDFLGKDSIRYYNEVPVEKRVFKNLQIFMENKKPGDDLFDRLNTTIMNKHLNDLMEGLTAKVFRTFNASNTLQEQLDELTDPKSSVTEKILAYNRANRAVAILCNHQRAVPKTFAKSMENLQVKITAKREAIEDAEKSFKDLKKEAKKTGSAAAKIAAGKKEKQVEKLKEQLMKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKNDVPIEKIYNKTQREKFQWAIDMAGPEFVF 543
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: gb|KPM06386.1| (DNA topoisomerase 1-like protein [Sarcoptes scabiei]) HSP 1 Score: 619.772 bits (1597), Expect = 0.000e+0 Identity = 327/564 (57.98%), Postives = 396/564 (70.21%), Query Frame = 0
Query: 351 VWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLVGFMDRKYS-------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+WKWWEEE+ +G KWK L+H GP+F PDY+ LPK V FYYN K M+LS EEVA FYA+ ++H+YT K+VFN+NFFKDWRK MT +E++IIT+LS C+F+++N Y+K +E+RK +KEEK K+KN ++G C++D H +KIGNFRIEPPGLFRGR ++ D+ + K +IRH VK + K+K K + YEKARELK + KIR DY DFKS EM RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHITL+ K+G Y V+FDFLGKDSIRY N V VEKRVFKN++ F+++K+ DDLFDRL T+ LN+YLNSLM GLTAKVFRT+NAS TLQ QL ELT+AD N+P KML+YNRANR VA+LCNHQRA PKT DK M+NL KI+ K+ +K+ KK YK S + DK KK L+ EQL KLE Q VDKEENK IALGTSKLNYLDPRISVAW KK+ VPI+K+YNKTQRDKFRWAIEM G DY F
Sbjct: 218 IWKWWEEERPGEGIKWKTLEHNGPVFPPDYEPLPKNVKFYYNGKHMELSPGAEEVASFYAKMLDHDYTSKDVFNKNFFKDWRKTMTDKEKEIITDLSLCNFKKMNEYFKDQTEKRKQMTKEEKLEIKKKNEEAVLKYGYCIVDGHKQKIGNFRIEPPGLFRGRGEHPKMGKLKKRVQPEDIIINIGDKAKAPIPPAGHKWKEIRHDNTVTWLASWTENIMGNVKYIMLNPSSKLKSIKDWQKYEKARELKKYVAKIRADYRTDFKSHEMMKRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLNEEKNGNQYVVDFDFLGKDSIRYINSVSVEKRVFKNLKHFIQHKQPGDDLFDRLTTSSLNKYLNSLMDGLTAKVFRTYNASNTLQQQLNELTKADMNLPEKMLAYNRANRSVALLCNHQRAVPKTFDKQMENLSVKIQDKKSQ-------IKEQKKIYKE--SKGDSAARDKHKKKLKTLEEQLKKLEVQKVDKEENKQIALGTSKLNYLDPRISVAWCKKWQVPIDKIYNKTQRDKFRWAIEMVGPDYQF 772
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: AHN59737.1 (topoisomerase 1, isoform E [Drosophila melanogaster]) HSP 1 Score: 606.29 bits (1562), Expect = 0.000e+0 Identity = 316/561 (56.33%), Postives = 387/561 (68.98%), Query Frame = 0
Query: 353 KWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKS---------------------------NQIRHVKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+WWEEEK DG KW L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y KEVFN NFFKD+RK MT ER+II + KC+F+E+ Y++ SE+RK SKEEK +K +N A+ EFG C+ID H EKIGNFR+EPPGLFRGR +G + R+ S N + + S+++ +G KG YE AR L I+KIR Y ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH +GK+ V FDF GKDSIRY+N V VEKRVFKN++LFME+K+ DDLFDRLNT +LNE+L LM+GLTAKVFRT+NAS TLQ QL+ LT+ VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E + +KK K LER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA +Y F
Sbjct: 48 RWWEEEKRADGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 593
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: AFH07393.1 (topoisomerase 1, isoform D [Drosophila melanogaster]) HSP 1 Score: 595.504 bits (1534), Expect = 0.000e+0 Identity = 311/552 (56.34%), Postives = 383/552 (69.38%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH------VKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DG KW L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y KEVFN NFFKD+RK MT ER+II + KC+F+E+ Y++ SE+RK SKEEK +K +N A+ EFG C+ID H EKIGNFR+EPPGLFRGR +G + R+ S+ ++RH + S+++ +G KG YE AR L I+KIR Y ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH +GK+ V FDF GKDSIRY+N V VEKRVFKN++LFME+K+ DDLFDRLNT +LNE+L LM+GLTAKVFRT+NAS TLQ QL+ LT+ VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E + +KK K LER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA +Y F
Sbjct: 434 DGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 970
BLAST of EMLSAG00000000293 vs. nr
Match: gi|343175107|gb|AEM00018.1| (topoisomerase 1B [Spodoptera exigua]) HSP 1 Score: 724.546 bits (1869), Expect = 0.000e+0 Identity = 380/663 (57.32%), Postives = 469/663 (70.74%), Query Frame = 0
Query: 265 EVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKK--------PKVKKVERVEVSKKSKSSKKNHKVKHEVV------SPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKS------------NQIRHVKSFLKIKRGKGYY------------------EKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
E+ +++S++D P +++ NK+R +SE+D+PL +RKK P E K K K KVK V P+ + +KK+ED+ EVWKWWEEEK DDGTKWKFL+H+GP+FAPDY+ LP+ V FYY+ K+M+LS + EEVAGFYAR ++HEYT K FN NFF DWRKVMT EE II +LSKC+F+E++ Y++ VSE+ +NR+KEEK A K KN IQ E+G C+ID H EKIGNFRIEPPGLFRGR +G + D K K N + + S+ + +G+ Y E AR+L I+ IR++Y D+K+KEMRVRQR+VALYFIDKLALRAGNEKD+DQADTVGCCSLRVEHI LH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN++LFMENK+ DDLFDRLNT LNE+L LM GLTAKVFRT+NAS TLQ QL+ELT+A ++P K+L+YNRANR VA+LCNHQRA PK H KSM+ L++KI+AKR+ ++AE+DL++A KA K GS EK+ DKKKKALER EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK VPIEK+YNKTQRDKFRWAI+MAG +Y+F
Sbjct: 271 ELPPEEESDEDSPSSERIGNKRRAP--SESEEDIPLLQRKKSKKKIKKEPTYDDDMDDEEEKPKKKKSKPVKVKQTQVKSEPNDGPSPTKRKKKQEDEPEVWKWWEEEKKDDGTKWKFLEHKGPVFAPDYEPLPENVKFYYDGKEMRLSQDAEEVAGFYARMLDHEYTTKSTFNNNFFNDWRKVMTHEETKIIKDLSKCNFKEMHAYFQSVSEKNRNRTKEEKAALKAKNEEIQKEYGFCIIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKRRVMPEDVLINCSKDSKIPKPPPGHKWKEVKHDNTVTWLASWTENVQGQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDVIRENYKNDWKAKEMRVRQRAVALYFIDKLALRAGNEKDDDQADTVGCCSLRVEHIALHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKDLMPGLTAKVFRTYNASITLQRQLDELTDASASIPEKILAYNRANRAVAVLCNHQRAVPKGHSKSMEALKEKIQAKRDQVDEAEEDLREAAKAAKR-GSVKEKLACDKKKKALERLREQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIYNKTQRDKFRWAIDMAGPEYIF 930
BLAST of EMLSAG00000000293 vs. nr
Match: gi|939676204|ref|XP_014284042.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Halyomorpha halys]) HSP 1 Score: 723.391 bits (1866), Expect = 0.000e+0 Identity = 426/843 (50.53%), Postives = 558/843 (66.19%), Query Frame = 0
Query: 86 KEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNN--AKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKH-------------EVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
KEK R + ++RH R+ +RD+ K+K++ + + + KE+ + ++R R+ R+ +++ +++ +++H S + + +KDKER+++ KR E ++ + + S + +E + ++ + +K+EP + L E+Q+ YNN K+E E E Q+DSEDD PL ++ N KR+ + ED E+D+PLS RKK K +K + + + + K E T +KK+E++ EVWKWWEEEK DG KW FL+H+GP+FAP Y+ LP V F+Y+ K+MKLS E EEVA FY R I+HEYT KE FN+NFFKDWRKVMT++E+D+IT+L KC+FR+INTY+ + SEERK SKEEKK KEKN + E+G C+ID H EKIGNF+IEPP LFRGR +G + R+ K ++RH VK + K+K K + YE AR+L I+KIR DY D+KSKEMR+RQR+VA+YFID LALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VP+EKRVFKN+QLFME K+G DDLFDRLNT+ILN++LN LM+GLTAKVFRT+NAS+TLQ QL+ELT+ + VP +L+YNRANR VAILCNHQR+ PKTH SM+ L++KI AK++ E+AEK K AKK KN GS E++V DKKKKAL+R EQL KLE Q D+EENKTIAL TSKLNYLDPRISVAW KK++VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 110 KEKHREKDKDRH-RDEKRDKEHRSSSSHKDKDKHSSTNSSSSKDKDKSHSSSKDKDKEKNSSKDKDRSDRDKHRDREKDKDRSKHNGDRKHSSSSSSSREKEKKDKERSKEAKPKRDE--FEEADDFQPSKVSEEEPVVVKSEPVDIKEEPIDDSYLSEDQNSC----YNNLTIKEEEDEAEEPQQEDSEDDAPLLSRTSNIKREIKSEDEEEDIPLSARKKVKKEKTGKRKKESDDEEEDDDFKPVKKKSSTVKKTKVKTEAPEETSPKKKKKQEEEQEVWKWWEEEKRPDGVKWTFLEHKGPVFAPPYEPLPPDVKFFYDGKEMKLSEEAEEVATFYGRMIDHEYTTKEAFNKNFFKDWRKVMTQKEKDVITDLKKCNFRQINTYFLRKSEERKAMSKEEKKVIKEKNEELVKEYGFCIIDGHKEKIGNFKIEPPSLFRGRGEHPKMGMLKRRVQPEDVLINCSKDSKIPKPPEGHKWKEVRHDNTVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAHSIDKIRKDYREDWKSKEMRIRQRAVAMYFIDILALRAGNEKDEDQADTVGCCSLRVEHITLHNEKDGKEYVVVFDFLGKDSIRYYNEVPIEKRVFKNLQLFMEGKKGSDDLFDRLNTSILNKHLNELMEGLTAKVFRTYNASWTLQQQLKELTDPNYTVPEMVLAYNRANRAVAILCNHQRSVPKTHQNSMEKLKEKIAAKKDQIEEAEKQYKYAKKDAKN-GSAKERIVADKKKKALDRLREQLTKLEVQETDREENKTIALSTSKLNYLDPRISVAWCKKYNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 944
BLAST of EMLSAG00000000293 vs. nr
Match: gi|939255986|ref|XP_014247767.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Cimex lectularius]) HSP 1 Score: 721.85 bits (1862), Expect = 0.000e+0 Identity = 394/695 (56.69%), Postives = 482/695 (69.35%), Query Frame = 0
Query: 238 YEEELHEEQDEFEEDRYNNAKQENME-VEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSK----------------KSKSSKKNHKVKHEVVSPTKSGGRKKK--EDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN-----------------------------------------QIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
Y+E +E+D+ +D YN + ME K ++DSE+DIPL+ + + S D +DDVPL+ RKK K +K + + K K+K+ KK+ KVK E + RKK+ E++ EVWKWWEEEK DG KW FL+H+GP+FAP Y+ LP V FYY+ K+++LS E EEVA FY R IEH+YT+KEVFN NFFKDW+K MT +ER++IT+LSKC+FR IN Y++K SEERK +KEEK K+KN E+G C+ID H EKIGNF+IEPP LFRGR +G + ++ + Q+++V S LK ++ YE AR+L S+I+KIR DY D+KSKEM++RQR+VA+YFIDKLALRAGNEKDEDQADTVGCCSLRVEHI L KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLF+E K+G DDLFDRLNTT+LN++L LM GLTAKVFRT+NAS+TLQ QL ELT+ D +P L+YNRANR VAILCNHQR+ PK+H KSM+NL++KI KRE E+AEK K AKK KN GS EK+V DKKKKALER EQL KLE Q D+EENKTIALGTSKLNYLDPRISVAW KK +VPIEKVYNKTQRDKFRWAI+MAG DYVF
Sbjct: 288 YDENDFKEEDD--DDSYNLHIETTMEESTFKEEEDSEEDIPLSSR-----KHSMQSDEDDDVPLTSRKKLKTEKQKSSKKRKKSFDSEEEEEDDFKPVKTKAQKKSSKVKQEQNTSATQSPRKKRKLEEEQEVWKWWEEEKKPDGVKWNFLEHKGPVFAPPYEPLPHDVKFYYDGKEVRLSEEAEEVATFYGRMIEHDYTQKEVFNNNFFKDWKKTMTPKERELITDLSKCNFRHINAYFQKKSEERKAMTKEEKAELKKKNEEQVQEYGFCIIDGHKEKIGNFKIEPPSLFRGRGEHPKMGMLKKRVMPEDVSINCSKDSKIPVPPPGHKWKEVKHDNTVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLASQIDKIRRDYREDWKSKEMKIRQRAVAMYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIQLFPEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFIEGKKGSDDLFDRLNTTVLNKHLTELMDGLTAKVFRTYNASWTLQQQLNELTKDDYTLPEMCLAYNRANRAVAILCNHQRSVPKSHQKSMENLKEKISNKREQIEEAEKQYKYAKKDAKN-GSAKEKIVADKKKKALERLKEQLRKLEVQETDREENKTIALGTSKLNYLDPRISVAWCKKHNVPIEKVYNKTQRDKFRWAIDMAGPDYVF 974
BLAST of EMLSAG00000000293 vs. nr
Match: gi|307182085|gb|EFN69463.1| (DNA topoisomerase 1 [Camponotus floridanus]) HSP 1 Score: 721.85 bits (1862), Expect = 0.000e+0 Identity = 424/855 (49.59%), Postives = 548/855 (64.09%), Query Frame = 0
Query: 107 EEERKVRKEKERKEREERHKREGRRDE---TEDERRLRKERERKEREERHK-REGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEF--------EEDRYNNAKQENMEVE----------------VKVQDDSEDDIPLAKKSKNKKRKSR--DEDSEDDVPLSKRKKPKVKKV---------------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------------------------------------YLVGFMDRKYSKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+++R + K+KER+ + +H G RD+ + KE+ R +++ K RE +++ + K+K++ K + + ++DK++ E + ++ +M +H+ E FH ++ E+K E +K+EP + EL E+ D EED A +E ++ +K ++DSE+D PL+ +SK R + D E+DVPLS RKKPK + EV + KS KK + K E SP K +K+E++ EVWKWWEEEK DGTKW FL+H+GP+FAP Y+ LP V FYYN K+ KLS + EEVA FYAR ++H+YT K+ FN NFF DWR+VMT ER IT+LSKC+F+E++ Y+ + SEERK +KEEK+ KEKN IQ E+G CVID H EKIGNF+IEPPGLFRGR +L + + + Q+++V S LK ++ YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI LH +DGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT+ +D K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI AK+EA + E +K AK+ K+ GS EKV +KKKK LER EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 203 DKDRNLSKDKERENK--KHSSSGERDKDRHSTSHSSGDKEKHRSSEKDKDKHRESSSSSKDKQHRHEKDKDRHRHDKSKHRDEKEKRDKDKEEIKIKEETDMKLNHATNER--FH-YNLEVKPE-----IKEEPMTQLELDEDDDSGGERPLYIKEEDDDEEAVKEEASMDSTDGNDTRLSDLHNTTLKTEEDSEEDKPLSSRSKVSPSVKRKIESDEEEDVPLSARKKPKRATSSKTKKKKRKHDGENDDDSEVESEEKSKKKV-RAKGEGASPRK----RKQEEEQEVWKWWEEEKKSDGTKWHFLEHKGPVFAPPYEPLPPNVKFYYNGKETKLSQDAEEVATFYARMLDHDYTTKDAFNNNFFHDWREVMTESERAKITDLSKCNFKEMHAYFLQKSEERKAMTKEEKQKIKEKNDEIQKEYGFCVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVLPEDVLINCSKDSNIPKPPAGHKWKEVRHDPNVTWLASWTE---NIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIKLHEQRDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTDPNDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIDAKKEAIAECELQVKDAKRDAKH-GSVKEKVTYEKKKKQLERLKEQLTKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1038
BLAST of EMLSAG00000000293 vs. nr
Match: gi|350404638|ref|XP_003487171.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Bombus impatiens]) HSP 1 Score: 721.079 bits (1860), Expect = 0.000e+0 Identity = 388/701 (55.35%), Postives = 492/701 (70.19%), Query Frame = 0
Query: 227 QQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENME-VEVKVQDDSEDDIPLAKKS--KNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGR-----------KKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY---------------------SKSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+Q +K++ EE ++EE+ + N+ + ++ +K +++S++D+PL+ +S ++S D + EDDVPLS RKK K + + +K + + +++ + P K GGR KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP V FYY K+MKLS + EEVA FYAR ++H+YT K FN NFF DWR+VMT ER I +LSKC+F+E+++Y+ + SEERK +KEEK+ KE N IQ E+G C+ID H EKIGNF+IEPPGLFRGR +G + R+ K ++RH VK + K+K K + YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT DD K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A +AE +K+AK+ K+ GS EKVV +KKKKAL+R EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 332 EQPLYIKEDDDDEEAMNEEEGSMDSTDGNDTRLSDLHNTTIKTEEESDEDMPLSARSMAPTSVKRSLDSEEEDDVPLSARKKSKKNDTKAKKKKRKHEDDEDEDEIEQK---PKKKGGRASKGENSSPRKKKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVKFYYCGKEMKLSQDAEEVATFYARMLDHDYTTKSAFNNNFFHDWREVMTESERAKINDLSKCNFKEMHSYFVQKSEERKAMTKEEKQKIKETNEQIQKEYGFCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKRRVMPEDILINCSKDSNIPKPPPGHKWKEVRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAISEAEHAVKEAKRDAKH-GSVKEKVVYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1028
BLAST of EMLSAG00000000293 vs. nr
Match: gi|987905862|ref|XP_015440538.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Dufourea novaeangliae] >gi|1016159729|gb|KZC06891.1| DNA topoisomerase 1 [Dufourea novaeangliae]) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 390/664 (58.73%), Postives = 476/664 (71.69%), Query Frame = 0
Query: 266 VKVQDDSEDDIPLAKKSK---NKKRKSRDEDSEDDVPLSKRKKPK-------VKKV------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLV-----GFMDRKYS--KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+K +++S++D+PL+ +SK KR+ +D E+DVPL RKK K +KK E+VE K K S+ + K + SP K KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP V FYYN K+MKLS +TEEVA FYAR ++H+YT K FN NFF DWR+VMT ER I++L+KC+F+E++TY+ + SEERK +K+EK+ KE+N IQ E+G C ID H EKIGNF+IEPPGLFRGR L+ + + S K +IRH VK + K+K K + YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT DD + K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK+EA AE +K AK+ K+ GS EKVV +KKKK L+R EQL KLE QA DKEENK IALGTSKLNYLDPRISVAW KK DVPI+K+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 374 IKTEEESDEDMPLSTRSKPNTTSKRRIYSDDEEEDVPLVVRKKSKKTETKAQIKKPKYEDEEEQVEQKPKKKRSRTS---KGDNTSPRK----KKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPSYEPLPPNVKFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERSKISDLNKCNFKEMHTYFLQKSEERKAMTKDEKQKIKEQNEEIQKEYGFCTIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSCIPKPPSGHKWKEIRHDPNVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTIAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKEAITDAELAVKDAKREAKH-GSVKEKVVYEKKKKTLDRLREQLTKLEVQATDKEENKEIALGTSKLNYLDPRISVAWCKKNDVPIDKIYNKTQRDKFRWAIDMAGPDYVF 1029
BLAST of EMLSAG00000000293 vs. nr
Match: gi|1134627525|ref|XP_019882816.1| (PREDICTED: DNA topoisomerase I, mitochondrial, partial [Camponotus floridanus]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 424/855 (49.59%), Postives = 548/855 (64.09%), Query Frame = 0
Query: 107 EEERKVRKEKERKEREERHKREGRRDE---TEDERRLRKERERKEREERHK-REGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEF--------EEDRYNNAKQENMEVE----------------VKVQDDSEDDIPLAKKSKNKKRKSR--DEDSEDDVPLSKRKKPKVKKV---------------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------------------------------------YLVGFMDRKYSKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+++R + K+KER+ + +H G RD+ + KE+ R +++ K RE +++ + K+K++ K + + ++DK++ E + ++ +M +H+ E FH ++ E+K E +K+EP + EL E+ D EED A +E ++ +K ++DSE+D PL+ +SK R + D E+DVPLS RKKPK + EV + KS KK + K E SP K +K+E++ EVWKWWEEEK DGTKW FL+H+GP+FAP Y+ LP V FYYN K+ KLS + EEVA FYAR ++H+YT K+ FN NFF DWR+VMT ER IT+LSKC+F+E++ Y+ + SEERK +KEEK+ KEKN IQ E+G CVID H EKIGNF+IEPPGLFRGR +L + + + Q+++V S LK ++ YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI LH +DGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT+ +D K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI AK+EA + E +K AK+ K+ GS EKV +KKKK LER EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 164 DKDRNLSKDKERENK--KHSSSGERDKDRHSTSHSSGDKEKHRSSEKDKDKHRESSSSSKDKQHRHEKDKDRHRHDKSKHRDEKEKRDKDKEEIKIKEETDMKLNHATNER--FH-YNLEVKPE-----IKEEPMTQLELDEDDDSGGERPLYIKEEDDDEEAVKEEASMDSTDGNDTRLSDLHNTTLKTEEDSEEDKPLSSRSKVSPSVKRKIESDEEEDVPLSARKKPKRATSSKTKKKKRKHDGENDDDSEVESEEKSKKKV-RAKGEGASPRK----RKQEEEQEVWKWWEEEKKSDGTKWHFLEHKGPVFAPPYEPLPPNVKFYYNGKETKLSQDAEEVATFYARMLDHDYTTKDAFNNNFFHDWREVMTESERAKITDLSKCNFKEMHAYFLQKSEERKAMTKEEKQKIKEKNDEIQKEYGFCVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVLPEDVLINCSKDSNIPKPPAGHKWKEVRHDPNVTWLASWTE---NIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIKLHEQRDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTDPNDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIDAKKEAIAECELQVKDAKRDAKH-GSVKEKVTYEKKKKQLERLKEQLTKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 999
BLAST of EMLSAG00000000293 vs. nr
Match: gi|913304894|ref|XP_013182884.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X3 [Amyelois transitella]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 403/720 (55.97%), Postives = 493/720 (68.47%), Query Frame = 0
Query: 222 EMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEV--------------EVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEV-----------SKKSKSSKKNHKVKHE---VVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH----------------------VKSFLKIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
E ++Q QV DEP + E+ EE ED Y M E+ ++DSE+DIPL ++ +KKR + +SE+D+PL +RKK K KKV++ + KK +K +K E VVSPTK +KK+E++ EVWKWWEEEK DDGTKW FL+H+GPLFAP Y+ LP V F Y+ K+++LS + EEVAGFYAR ++H+YT K+ FN NFF DWRKVMT+EE +ITNLSKCDF+E+ Y+ VSE+ KNR+KEEK A K KN IQ E+G C ID H EKIGNFRIEPPGLFRGR +G + R+ K ++RH + K+K K + YE AR+L I+KIRD Y D+K+KEMRVRQR+VALYFID+LALRAGNEKD+DQADTVGCCSLRVEHI LH KDG+++ V FDFLGKDSIRY+N V VEKRVFKN++LFMENK+ DDLFDRLNT LNE+L LM GLTAKVFRT+NAS TLQ QL+ELT+A ++P K+L+YNRANR VA+LCNHQRA PK H KSM+ L++KI+AKR+ E+AE+DLK A KA K GS EK++ DKKKKALER EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK VPIEK+YNKTQRDKFRWAI+MAG +YVF
Sbjct: 238 ESSVKQDPIQV-DEPVVKNEIKEEP----EDGYGGFNNTTMSSCDYNLSQFKDEPLSELPQEEDSEEDIPLLERMASKKRPA--SESEEDIPLLQRKKLKKKKVKKEPIYDDEEDEEIKPKKKKIKPEKRKSIKQEPDEVVSPTKK--KKKQEEEQEVWKWWEEEKKDDGTKWTFLEHKGPLFAPPYEPLPSNVKFRYDGKEVRLSQDAEEVAGFYARMLDHDYTTKDTFNNNFFADWRKVMTKEETKLITNLSKCDFKEMQAYFLSVSEKNKNRTKEEKAALKAKNEEIQKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKRRVMPEDVLINCSKDSKIPKPPAGHKWKEVRHDNTVTWLASWTENVQGQSKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRDTYRNDWKAKEMRVRQRAVALYFIDRLALRAGNEKDDDQADTVGCCSLRVEHIELHKEKDGQEHVVVFDFLGKDSIRYYNEVAVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKELMPGLTAKVFRTYNASITLQRQLDELTDAKASIPEKILAYNRANRAVAVLCNHQRAVPKGHSKSMEALKEKIQAKRDQVEEAERDLKDATKAAKR-GSEKEKIICDKKKKALERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIYNKTQRDKFRWAIDMAGPEYVF 947
BLAST of EMLSAG00000000293 vs. nr
Match: gi|646723372|gb|KDR24006.1| (DNA topoisomerase 1 [Zootermopsis nevadensis]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 400/706 (56.66%), Postives = 487/706 (68.98%), Query Frame = 0
Query: 227 QQEQQVKDEP-QYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPL------------AKKSKNKKRKSRDEDSEDD-VPLSKRKKPKVKKVERVEVS-----KKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKSN------QIRHVKSFL----------------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
Q +K+EP + E L +E + N K E ++KV++D EDDIPL A +S + K R EDS+DD VPL RKK K + ++ E S K K K VK E+ + +KK+E++ EVWKWWEEEK DDGTKWKFL+H+GP+FAP YDRLP + F+Y+ K+M LS TEEVA FYAR ++H+YT KE FN+NFFKDWRKVMT +E++ IT+LSKC+F++++ Y+ +EERK SKEEKK K++N I E+G CVID H E+IGNF+IEPPGLFRGR +G + D K K +IRH K+ K+K K + YE AR+L IEKIR +Y DFKSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI+LH+ KDGKDY V FDF GKDSIRY+N V VEKRVFKN+QLFM+NK DDLFDRLNTT+LN++LN LM+GLTAKVFRT+NASFTLQ+QL++LT+ D V K+L+YNRANR VAILCNHQRA PKTH KSM+NL+ KI AK+E + AE+ K K +K GS K+ M+K+KKALE+ EQL KLE QA DKEENK IAL TSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 256 QPMAWIKEEPVNHNERLVHSVNESGDQSSVNFKSETA-TKIKVEEDIEDDIPLWRSEDRAHRSGLASRSVVGEVKRRLEDSDDDDVPLMARKKIKKESKKQKEESDEEEFKPVKKKSKKGNVKEEITPQSSPRKKKKEEEQQEVWKWWEEEKKDDGTKWKFLEHKGPVFAPLYDRLPPDIKFFYDGKEMTLSEPTEEVASFYARMLDHDYTTKEAFNKNFFKDWRKVMTDKEKERITDLSKCNFKQMHKYFLAKAEERKAMSKEEKKKLKDQNEEIVKEYGFCVIDGHTERIGNFKIEPPGLFRGRGEHPKMGMLKKRVIPEDVIINCSKDSKIPKPPDGHKWREIRHDKNVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAKCIEKIRQEYQDDFKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHISLHSQKDGKDYVVVFDFPGKDSIRYYNEVSVEKRVFKNLQLFMQNKSTGDDLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASFTLQEQLDKLTDPDYTVQEKILAYNRANRAVAILCNHQRAVPKTHAKSMENLKGKIDAKKEMVQDAERQYKDVKHEHKRNGSAKNKIDMEKRKKALEKLREQLAKLELQATDKEENKEIALSTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 960
BLAST of EMLSAG00000000293 vs. nr
Match: gi|768417486|ref|XP_011549382.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Plutella xylostella]) HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0 Identity = 385/655 (58.78%), Postives = 470/655 (71.76%), Query Frame = 0
Query: 271 DSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERV-----EVS------KKSKSSKKNHKVKHE-VVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDR---------------------KYSKSNQIRH----------------------VKSFLKIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DSE+D PL ++ K+R + E SEDD PL+ RKKPK KK+++ E+S KK +K KVK E SPTK +KK++D+ EVWKWWEEEK DDGTKWKFL+H+GPLFAP Y+ +P+ V F Y+ K ++LS + EEVAGFYAR ++H+YT K VFN NFF DWRKVMT +E +I +L KCDF+E+ Y++ VSE+ KNR+KEEK K N IQ E+G C+ID H EKIGNFRIEPPGLFRGR +G + + K K ++RH + K+K K + YE AR+L I+KIRD Y D+K+KEMRVRQR+VALYFID+LALRAGNEKD+DQADTVGCCSLRVEHI LH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN++LFMENK+ DDLFDRLNT LNE+L LM GLTAKVFRT+NAS TLQ QL+ELT+ D ++P K+L+YNRANR VA+LCNHQRA PK HDKSM+ L++KI+AKR+ ++AE+D++Q+ KA K GS EK+ DKK KALER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK+YNKTQRDKFRWAI+MAG +YVF
Sbjct: 293 DSEEDTPLLERMAPKRRAVKSE-SEDDTPLTMRKKPKKKKIKKESGYDEEMSDDEPKAKKPTKTKPAAKVKTEDGPSPTKR--KKKQDDEPEVWKWWEEEKKDDGTKWKFLEHKGPLFAPPYEPIPENVKFRYDGKVVRLSQDAEEVAGFYARMLDHDYTTKSVFNNNFFADWRKVMTHDEAKLIKDLKKCDFKEMQAYFQSVSEKNKNRTKEEKAQLKATNEEIQKEYGFCIIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKKRVMPEDVLINCSKDSNVPKPPKGHKWKEVRHDNTVTWLASWTENVQGQTKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRDTYRSDWKAKEMRVRQRAVALYFIDRLALRAGNEKDDDQADTVGCCSLRVEHIALHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKELMPGLTAKVFRTYNASITLQRQLDELTDGDASIPEKILAYNRANRAVAVLCNHQRAVPKGHDKSMEALKEKIQAKRDQIDEAEEDVRQSAKAAKR-GSVKEKMNHDKKTKALERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIYNKTQRDKFRWAIDMAGPEYVF 943
BLAST of EMLSAG00000000293 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold462_size163801-snap-gene-0.41 (protein:Tk04567 transcript:maker-scaffold462_size163801-snap-gene-0.41-mRNA-1 annotation:"topoisomerase 1b") HSP 1 Score: 806.594 bits (2082), Expect = 0.000e+0 Identity = 424/691 (61.36%), Postives = 501/691 (72.50%), Query Frame = 0
Query: 247 DEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKK------RKSRDEDSEDDVPLSKRKKPK----------------VKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEE--EKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSK-----------------------------------------SNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
D+ +D + K+E M+ E DSE+D PLA+ SK +K D+D ++DVP++KRK+ K VK + + +K K + +P + G + KKE+ EVWKWWEE K DDGTKW+FL+H+GPLFAPDY+ LP VHFYY K+M+LS +TEEVA FY R ++H+YT KEVFNRN+ KDWRKVM +E++II ++SKCDF+EI ++KKVSEERK RSK+++KAEKE+N AIQ E+G C ID H EKIGNFRIEPP LFRGR G + ++ S NQI++V S LK ++ YEKARELK I KIRDDYT DFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDG++Y VEFDFLGKDSIRY+N VPVEKRVFKNVQLFMENK+ DDLFDRLNT+ILNEYLN+LM GLTAKVFRT+NAS TLQ+QL +LTE DDNVPAKMLSYNRANR VA+LCNHQRA PKTH+KSM NLQ KI+ K++A KAEK+ K AKK++KNGGS + K+ MDKKKKALER +EQL+KLETQAVDKEENK+IALGTSKLNYLDPRISVAW KKFDVPIEKVYNKTQR+KFRWAIEMAG +Y F
Sbjct: 236 DDDSQDSQASMKEEPMDGE-----DSEEDKPLARNSKKRKVNDDEDEFQPDDDDDEDVPIAKRKRVKKEEPRYKEEDDDYQEDVKPAKSKKKAKPEKKTPSKPASSSASSNP-RGGKKVKKEENQEVWKWWEETTHKKDDGTKWQFLEHKGPLFAPDYEPLPSHVHFYYEGKRMRLSQDTEEVATFYGRMLDHDYTTKEVFNRNYMKDWRKVMNEKEKEIIRDISKCDFKEIGVHFKKVSEERKGRSKDDRKAEKERNEAIQKEYGFCTIDGHVEKIGNFRIEPPSLFRGRGEHPKQGMLKKRVSPEDVIINCSKNSDIPKPPEGRKWKKVQHDNTVTWLACWTENIQNQIKYVMLNPSSKLKGEKDMAKYEKARELKKLIHKIRDDYTADFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHPEKDGQEYVVEFDFLGKDSIRYNNCVPVEKRVFKNVQLFMENKKAGDDLFDRLNTSILNEYLNTLMPGLTAKVFRTYNASITLQEQLNQLTEEDDNVPAKMLSYNRANRAVAVLCNHQRAVPKTHEKSMTNLQTKIEGKKDAVNKAEKEFKAAKKSHKNGGSATSKINMDKKKKALERLMEQLNKLETQAVDKEENKSIALGTSKLNYLDPRISVAWCKKFDVPIEKVYNKTQREKFRWAIEMAGPEYQF 920 The following BLAST results are available for this feature:
BLAST of EMLSAG00000000293 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000000293 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 7
BLAST of EMLSAG00000000293 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 1
BLAST of EMLSAG00000000293 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 22
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BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 24
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BLAST of EMLSAG00000000293 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000000293 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 1
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s1044:15439..19815- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000000293-683059 ID=EMLSAG00000000293-683059|Name=EMLSAG00000000293|organism=Lepeophtheirus salmonis|type=gene|length=4377bp|location=Sequence derived from alignment at LSalAtl2s1044:15439..19815- (Lepeophtheirus salmonis)back to top Add to Basket
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