EMLSAG00000000440, EMLSAG00000000440-683206 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Homology
BLAST of EMLSAG00000000440 vs. GO
Match: - (symbol:Adam17 "ADAM metallopeptidase domain 17" species:10116 "Rattus norvegicus" [GO:0001666 "response to hypoxia" evidence=IEA;ISO] [GO:0001934 "positive regulation of protein phosphorylation" evidence=ISO] [GO:0002467 "germinal center formation" evidence=IEA;ISO] [GO:0004222 "metalloendopeptidase activity" evidence=IEA;ISO;IMP] [GO:0005112 "Notch binding" evidence=IEA;ISO;ISS] [GO:0005138 "interleukin-6 receptor binding" evidence=IEA;ISO] [GO:0005178 "integrin binding" evidence=IEA;ISO] [GO:0005737 "cytoplasm" evidence=IEA;ISO] [GO:0005886 "plasma membrane" evidence=IDA] [GO:0005887 "integral component of plasma membrane" evidence=IEA;ISO] [GO:0005911 "cell-cell junction" evidence=IEA;ISO] [GO:0005925 "focal adhesion" evidence=IEA;ISO] [GO:0006508 "proteolysis" evidence=TAS] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IC;ISO;IMP;TAS] [GO:0007155 "cell adhesion" evidence=ISO] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=IEA;ISO] [GO:0007219 "Notch signaling pathway" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=IEA;ISO;ISS] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA] [GO:0008237 "metallopeptidase activity" evidence=ISO;IMP] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0008284 "positive regulation of cell proliferation" evidence=IEA;ISO] [GO:0009986 "cell surface" evidence=IEA;ISO;IDA] [GO:0010820 "positive regulation of T cell chemotaxis" evidence=IEA;ISO] [GO:0015629 "actin cytoskeleton" evidence=IEA;ISO] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016324 "apical plasma membrane" evidence=IEA;ISO] [GO:0017124 "SH3 domain binding" evidence=IEA] [GO:0030165 "PDZ domain binding" evidence=IEA;ISO] [GO:0030183 "B cell differentiation" evidence=IEA;ISO] [GO:0030307 "positive regulation of cell growth" evidence=IEA;ISO] [GO:0030335 "positive regulation of cell migration" evidence=ISO] [GO:0030511 "positive regulation of transforming growth factor beta receptor signaling pathway" evidence=IEA;ISO] [GO:0031659 "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle" evidence=IEA;ISO] [GO:0032496 "response to lipopolysaccharide" evidence=IEA;ISO] [GO:0032587 "ruffle membrane" evidence=IEA;ISO] [GO:0032717 "negative regulation of interleukin-8 production" evidence=IEA;ISO] [GO:0032722 "positive regulation of chemokine production" evidence=IEA;ISO] [GO:0033025 "regulation of mast cell apoptotic process" evidence=IEA;ISO] [GO:0033077 "T cell differentiation in thymus" evidence=IEA;ISO] [GO:0033627 "cell adhesion mediated by integrin" evidence=IEA;ISO] [GO:0035313 "wound healing, spreading of epidermal cells" evidence=IEA;ISO] [GO:0035625 "epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway" evidence=IEA;ISO] [GO:0042493 "response to drug" evidence=IEA;ISO] [GO:0043066 "negative regulation of apoptotic process" evidence=IDA] [GO:0045121 "membrane raft" evidence=IEA;ISO] [GO:0045741 "positive regulation of epidermal growth factor-activated receptor activity" evidence=ISO] [GO:0048536 "spleen development" evidence=IEA;ISO] [GO:0048870 "cell motility" evidence=ISO] [GO:0051088 "PMA-inducible membrane protein ectodomain proteolysis" evidence=IEA;ISO] [GO:0051272 "positive regulation of cellular component movement" evidence=ISO] [GO:0055099 "response to high density lipoprotein particle" evidence=IEA;ISO] InterPro:IPR001590 InterPro:IPR002870 InterPro:IPR024079 Pfam:PF01562 PROSITE:PS00142 PROSITE:PS50215 RGD:620404 GO:GO:0016021 GO:GO:0005886 GO:GO:0043066 GO:GO:0009986 GO:GO:0008270 GO:GO:0007219 GO:GO:0005112 GO:GO:0004222 Gene3D:3.40.390.10 Gene3D:4.10.70.10 InterPro:IPR001762 Pfam:PF00200 SMART:SM00050 SUPFAM:SSF57552 PROSITE:PS50214 GO:GO:0006509 GO:GO:0007220 MEROPS:M12.217 eggNOG:NOG269976 KO:K06059 CTD:6868 HOGENOM:HOG000033797 HOVERGEN:HBG050457 BRENDA:3.4.24.86 EMBL:AJ012603 RefSeq:NP_064702.1 UniGene:Rn.144585 ProteinModelPortal:Q9Z1K9 SMR:Q9Z1K9 IntAct:Q9Z1K9 STRING:10116.ENSRNOP00000010648 BindingDB:Q9Z1K9 ChEMBL:CHEMBL2523 PhosphoSite:Q9Z1K9 PaxDb:Q9Z1K9 GeneID:57027 KEGG:rno:57027 InParanoid:Q9Z1K9 NextBio:611284 PRO:PR:Q9Z1K9 Genevestigator:Q9Z1K9 Uniprot:Q9Z1K9) HSP 1 Score: 63.929 bits (154), Expect = 1.525e-9 Identity = 91/351 (25.93%), Postives = 143/351 (40.74%), Query Frame = 0
Query: 92 RDMKEGHAYG-----VLNEKGFFRGTFEVNDD--KYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIEN---------------ELNDEFKMDXPPSEXSTRFGDQFIENGPY---CVLNIEVDKSLYYSFDRNIQDIK-QFVFMTVMGTNKIYREA--DLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSN-----EKSSVEPKIFIEDFSFAPAPH-TDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQI-----IDGDRNYNVGFITTGGFRTQYQT---ELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEI 392
+D GH G VL G T +N D +Y IE R++++ KD +YKS D+ + EL + +D PSE R + E P C L + D Y R + ++ + + IYR D G+ +Q R+ + +PQ G R + + EK + + K+ +E FS A + CL+++F+ Q+F TLG+A VG G P+ + + N G +T + T +L HE GH+ G+ HD G P + G +M PIA + +N++ FS CSK+ I
Sbjct: 112 QDFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNIEPLWRFVNDT-KDKRMLVYKSEDIKDFSRLQSPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRI-LKSPQEVKP-GERHFNMAKSFPNEEKDAWDVKMLLEQFSLDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPGVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNE-DQGGKYVMYPIAVSGDHENNKMFSNCSKQSI 458
BLAST of EMLSAG00000000440 vs. GO
Match: - (symbol:Adam17 "A disintegrin and metalloproteinase domain 17 (Tumor necrosis factor, alpha, converting enzyme), isoform CRA_a" species:10116 "Rattus norvegicus" [GO:0001666 "response to hypoxia" evidence=IEA] [GO:0002467 "germinal center formation" evidence=IEA] [GO:0004222 "metalloendopeptidase activity" evidence=IEA] [GO:0005138 "interleukin-6 receptor binding" evidence=IEA] [GO:0005178 "integrin binding" evidence=IEA] [GO:0005737 "cytoplasm" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0005911 "cell-cell junction" evidence=IEA] [GO:0005925 "focal adhesion" evidence=IEA] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=IEA] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0008284 "positive regulation of cell proliferation" evidence=IEA] [GO:0009986 "cell surface" evidence=IEA] [GO:0010820 "positive regulation of T cell chemotaxis" evidence=IEA] [GO:0015629 "actin cytoskeleton" evidence=IEA] [GO:0016324 "apical plasma membrane" evidence=IEA] [GO:0030165 "PDZ domain binding" evidence=IEA] [GO:0030183 "B cell differentiation" evidence=IEA] [GO:0030307 "positive regulation of cell growth" evidence=IEA] [GO:0030511 "positive regulation of transforming growth factor beta receptor signaling pathway" evidence=IEA] [GO:0031659 "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle" evidence=IEA] [GO:0032496 "response to lipopolysaccharide" evidence=IEA] [GO:0032587 "ruffle membrane" evidence=IEA] [GO:0032717 "negative regulation of interleukin-8 production" evidence=IEA] [GO:0032722 "positive regulation of chemokine production" evidence=IEA] [GO:0033025 "regulation of mast cell apoptotic process" evidence=IEA] [GO:0033077 "T cell differentiation in thymus" evidence=IEA] [GO:0033627 "cell adhesion mediated by integrin" evidence=IEA] [GO:0035313 "wound healing, spreading of epidermal cells" evidence=IEA] [GO:0035625 "epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0045121 "membrane raft" evidence=IEA] [GO:0048536 "spleen development" evidence=IEA] [GO:0051088 "PMA-inducible membrane protein ectodomain proteolysis" evidence=IEA] [GO:0055099 "response to high density lipoprotein particle" evidence=IEA] InterPro:IPR001590 InterPro:IPR002870 InterPro:IPR024079 Pfam:PF01562 PROSITE:PS50215 RGD:620404 GO:GO:0005737 GO:GO:0007173 GO:GO:0030307 GO:GO:0009986 GO:GO:0005887 GO:GO:0045121 GO:GO:0042493 GO:GO:0015629 GO:GO:0016324 GO:GO:0008284 GO:GO:0008270 GO:GO:0032496 GO:GO:0001666 GO:GO:0032722 GO:GO:0005911 GO:GO:0005925 GO:GO:0055099 GO:GO:0004222 GO:GO:0035313 TreeFam:TF314733 Gene3D:3.40.390.10 Gene3D:4.10.70.10 InterPro:IPR001762 Pfam:PF00200 SMART:SM00050 SUPFAM:SSF57552 PROSITE:PS50214 GeneTree:ENSGT00670000097974 GO:GO:0051088 GO:GO:0010820 GO:GO:0007229 MEROPS:M12.217 OMA:KVCCRDE OrthoDB:EOG7S4X58 GO:GO:0030183 GO:GO:0033627 GO:GO:0035625 GO:GO:0002467 GO:GO:0032717 GO:GO:0031659 GO:GO:0030511 GO:GO:0033025 GO:GO:0048536 GO:GO:0033077 GO:GO:0032587 UniGene:Rn.144585 EMBL:CH473947 EMBL:AABR06043295 Ensembl:ENSRNOT00000010648 NextBio:35583839 PRO:PR:G3V711 Uniprot:G3V711) HSP 1 Score: 63.929 bits (154), Expect = 1.784e-9 Identity = 94/364 (25.82%), Postives = 148/364 (40.66%), Query Frame = 0
Query: 79 EMDYYVGFVVTRNRDMKEGHAYG-----VLNEKGFFRGTFEVNDD--KYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIEN---------------ELNDEFKMDXPPSEXSTRFGDQFIENGPY---CVLNIEVDKSLYYSFDRNIQDIK-QFVFMTVMGTNKIYREA--DLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSN-----EKSSVEPKIFIEDFSFAPAPH-TDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQI-----IDGDRNYNVGFITTGGFRTQYQT---ELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEI 392
E +Y V + +D GH G VL G T +N D +Y IE R++++ KD +YKS D+ + EL + +D PSE R + E P C L + D Y R + ++ + + IYR D G+ +Q R+ + +PQ G R + + EK + + K+ +E FS A + CL+++F+ Q+F TLG+A VG G P+ + + N G +T + T +L HE GH+ G+ HD G P + G +M PIA + +N++ FS CSK+ I
Sbjct: 104 ESEYSVKW-----QDFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNIEPLWRFVNDT-KDKRMLVYKSEDIKDFSRLQSPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRI-LKSPQEVKP-GERHFNMAKSFPNEEKDAWDVKMLLEQFSLDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPGVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNE-DQGGKYVMYPIAVSGDHENNKMFSNCSKQSI 458
BLAST of EMLSAG00000000440 vs. GO
Match: - (symbol:ADAM17 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0001666 "response to hypoxia" evidence=IEA] [GO:0002467 "germinal center formation" evidence=IEA] [GO:0004222 "metalloendopeptidase activity" evidence=IEA] [GO:0005112 "Notch binding" evidence=IEA] [GO:0005138 "interleukin-6 receptor binding" evidence=IEA] [GO:0005178 "integrin binding" evidence=IEA] [GO:0005737 "cytoplasm" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0005911 "cell-cell junction" evidence=IEA] [GO:0005925 "focal adhesion" evidence=IEA] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0008284 "positive regulation of cell proliferation" evidence=IEA] [GO:0009986 "cell surface" evidence=IEA] [GO:0010820 "positive regulation of T cell chemotaxis" evidence=IEA] [GO:0015629 "actin cytoskeleton" evidence=IEA] [GO:0016324 "apical plasma membrane" evidence=IEA] [GO:0030165 "PDZ domain binding" evidence=IEA] [GO:0030183 "B cell differentiation" evidence=IEA] [GO:0030307 "positive regulation of cell growth" evidence=IEA] [GO:0030511 "positive regulation of transforming growth factor beta receptor signaling pathway" evidence=IEA] [GO:0031659 "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle" evidence=IEA] [GO:0032496 "response to lipopolysaccharide" evidence=IEA] [GO:0032587 "ruffle membrane" evidence=IEA] [GO:0032717 "negative regulation of interleukin-8 production" evidence=IEA] [GO:0032722 "positive regulation of chemokine production" evidence=IEA] [GO:0033025 "regulation of mast cell apoptotic process" evidence=IEA] [GO:0033077 "T cell differentiation in thymus" evidence=IEA] [GO:0033627 "cell adhesion mediated by integrin" evidence=IEA] [GO:0035313 "wound healing, spreading of epidermal cells" evidence=IEA] [GO:0035625 "epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0045121 "membrane raft" evidence=IEA] [GO:0048536 "spleen development" evidence=IEA] [GO:0051088 "PMA-inducible membrane protein ectodomain proteolysis" evidence=IEA] [GO:0055099 "response to high density lipoprotein particle" evidence=IEA] InterPro:IPR001590 InterPro:IPR002870 InterPro:IPR024079 Pfam:PF01562 PROSITE:PS50215 GO:GO:0005737 GO:GO:0007173 GO:GO:0030307 GO:GO:0009986 GO:GO:0005887 GO:GO:0045121 GO:GO:0042493 GO:GO:0015629 GO:GO:0016324 GO:GO:0008284 GO:GO:0008270 GO:GO:0032496 GO:GO:0001666 GO:GO:0032722 GO:GO:0005911 GO:GO:0005925 GO:GO:0055099 GO:GO:0004222 GO:GO:0035313 TreeFam:TF314733 Gene3D:3.40.390.10 Gene3D:4.10.70.10 InterPro:IPR001762 Pfam:PF00200 SMART:SM00050 SUPFAM:SSF57552 PROSITE:PS50214 GeneTree:ENSGT00670000097974 GO:GO:0051088 GO:GO:0010820 OMA:KVCCRDE OrthoDB:EOG7S4X58 GO:GO:0030183 GO:GO:0033627 GO:GO:0035625 GO:GO:0002467 GO:GO:0032717 GO:GO:0031659 GO:GO:0030511 GO:GO:0033025 GO:GO:0048536 GO:GO:0033077 GO:GO:0032587 EMBL:DAAA02031941 Ensembl:ENSBTAT00000065783 Uniprot:G3MZB3) HSP 1 Score: 62.7734 bits (151), Expect = 3.614e-9 Identity = 88/326 (26.99%), Postives = 136/326 (41.72%), Query Frame = 0
Query: 112 TFEVNDD--KYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIEN----------ELNDEFKM------DXPPSEXSTRFGDQFIEN--GPYCVLNIEVDKSLYYSFDRNIQDIK-QFVFMTVMGTNKIYREA--DLVTIDGHPIQFVVGRLQVNTPQSCNSTGR-----RSYRCSNEKSSVEPKIFIEDFSFAPAPH-TDYCLSYVFSAQNFG-ATLGIAXVG--------GVXEPQIID--GDRN--YNVGFITTGGFRTQYQT---ELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEI 392
T +N D +Y IE R +++ KD +YKS D+ N+ + N+E + PP E R + N C L + D Y R + ++ + + IYR D G+ IQ R+ + +PQ R +SY + EK + + K+ +E FSF A + CL+++F+ Q+F TLG+A VG GV G +N N G +T + T +L HE GH+ G+ HD G P + G +M PIA + +N++ FS CSK+ I
Sbjct: 138 TIRINTDGAEYNIEPLWRLINDT-KDKRMLVYKSEDIKNVSRLQSPKVCGYIKANNEELLPKGLVDSEPPDELVHRVKRRADPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRI-LKSPQVVKPGERHFNMAKSYP-NEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNE-DQGGKYVMYPIAVSGDHENNKMFSNCSKQSI 459
BLAST of EMLSAG00000000440 vs. GO
Match: - (symbol:ADAM17 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0004222 "metalloendopeptidase activity" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] InterPro:IPR001590 InterPro:IPR002870 InterPro:IPR024079 Pfam:PF01562 PROSITE:PS50215 GO:GO:0006508 GO:GO:0008270 GO:GO:0004222 Gene3D:3.40.390.10 Gene3D:4.10.70.10 InterPro:IPR001762 Pfam:PF00200 SMART:SM00050 SUPFAM:SSF57552 PROSITE:PS50214 GeneTree:ENSGT00670000097974 EMBL:DAAA02031941 Ensembl:ENSBTAT00000001519 Uniprot:E1B867) HSP 1 Score: 62.3882 bits (150), Expect = 5.203e-9 Identity = 88/326 (26.99%), Postives = 136/326 (41.72%), Query Frame = 0
Query: 112 TFEVNDD--KYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIEN----------ELNDEFKM------DXPPSEXSTRFGDQFIEN--GPYCVLNIEVDKSLYYSFDRNIQDIK-QFVFMTVMGTNKIYREA--DLVTIDGHPIQFVVGRLQVNTPQSCNSTGR-----RSYRCSNEKSSVEPKIFIEDFSFAPAPH-TDYCLSYVFSAQNFG-ATLGIAXVG--------GVXEPQIID--GDRN--YNVGFITTGGFRTQYQT---ELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEI 392
T +N D +Y IE R +++ KD +YKS D+ N+ + N+E + PP E R + N C L + D Y R + ++ + + IYR D G+ IQ R+ + +PQ R +SY + EK + + K+ +E FSF A + CL+++F+ Q+F TLG+A VG GV G +N N G +T + T +L HE GH+ G+ HD G P + G +M PIA + +N++ FS CSK+ I
Sbjct: 135 TIRINTDGAEYNIEPLWRLINDT-KDKRMLVYKSEDIKNVSRLQSPKVCGYIKANNEELLPKGLVDSEPPDELVHRVKRRADPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRI-LKSPQVVKPGERHFNMAKSYP-NEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNE-DQGGKYVMYPIAVSGDHENNKMFSNCSKQSI 456
BLAST of EMLSAG00000000440 vs. GO
Match: - (symbol:ADAM17 "Disintegrin and metalloproteinase domain-containing protein 17" species:9606 "Homo sapiens" [GO:0001666 "response to hypoxia" evidence=IDA] [GO:0001934 "positive regulation of protein phosphorylation" evidence=IMP] [GO:0002446 "neutrophil mediated immunity" evidence=IC] [GO:0002467 "germinal center formation" evidence=ISS] [GO:0002690 "positive regulation of leukocyte chemotaxis" evidence=IC] [GO:0004222 "metalloendopeptidase activity" evidence=IMP;IDA;TAS] [GO:0005112 "Notch binding" evidence=IDA] [GO:0005138 "interleukin-6 receptor binding" evidence=IPI] [GO:0005178 "integrin binding" evidence=IPI] [GO:0005515 "protein binding" evidence=IPI] [GO:0005737 "cytoplasm" evidence=IDA] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0005887 "integral component of plasma membrane" evidence=IDA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IDA;IMP] [GO:0006915 "apoptotic process" evidence=TAS] [GO:0007155 "cell adhesion" evidence=IDA] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=IDA;TAS] [GO:0007219 "Notch signaling pathway" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=IDA] [GO:0008237 "metallopeptidase activity" evidence=IDA;IMP;TAS] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0008284 "positive regulation of cell proliferation" evidence=IMP] [GO:0009986 "cell surface" evidence=IDA] [GO:0010820 "positive regulation of T cell chemotaxis" evidence=IMP] [GO:0015629 "actin cytoskeleton" evidence=IDA] [GO:0016324 "apical plasma membrane" evidence=IDA] [GO:0017124 "SH3 domain binding" evidence=IEA] [GO:0022617 "extracellular matrix disassembly" evidence=TAS] [GO:0030165 "PDZ domain binding" evidence=IPI] [GO:0030183 "B cell differentiation" evidence=ISS] [GO:0030198 "extracellular matrix organization" evidence=TAS] [GO:0030307 "positive regulation of cell growth" evidence=IMP] [GO:0030335 "positive regulation of cell migration" evidence=IMP] [GO:0030511 "positive regulation of transforming growth factor beta receptor signaling pathway" evidence=ISS] [GO:0030574 "collagen catabolic process" evidence=TAS] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=TAS] [GO:0031659 "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle" evidence=IDA] [GO:0032496 "response to lipopolysaccharide" evidence=IDA] [GO:0032717 "negative regulation of interleukin-8 production" evidence=IMP] [GO:0032722 "positive regulation of chemokine production" evidence=IMP] [GO:0033025 "regulation of mast cell apoptotic process" evidence=ISS] [GO:0033077 "T cell differentiation in thymus" evidence=ISS] [GO:0033627 "cell adhesion mediated by integrin" evidence=IDA] [GO:0035313 "wound healing, spreading of epidermal cells" evidence=IEP] [GO:0035625 "epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway" evidence=IMP] [GO:0042493 "response to drug" evidence=ISS] [GO:0045121 "membrane raft" evidence=IDA] [GO:0045741 "positive regulation of epidermal growth factor-activated receptor activity" evidence=IDA;IMP] [GO:0048011 "neurotrophin TRK receptor signaling pathway" evidence=TAS] [GO:0048536 "spleen development" evidence=ISS] [GO:0048870 "cell motility" evidence=ISS] [GO:0051088 "PMA-inducible membrane protein ectodomain proteolysis" evidence=IMP;IDA] [GO:0051272 "positive regulation of cellular component movement" evidence=ISS] [GO:0055099 "response to high density lipoprotein particle" evidence=IDA] [GO:0060397 "JAK-STAT cascade involved in growth hormone signaling pathway" evidence=TAS] [GO:0097190 "apoptotic signaling pathway" evidence=TAS] [GO:0005911 "cell-cell junction" evidence=IDA] [GO:0005925 "focal adhesion" evidence=IDA] [GO:0032587 "ruffle membrane" evidence=IDA] Reactome:REACT_578 Reactome:REACT_2001 InterPro:IPR001590 InterPro:IPR002870 InterPro:IPR024079 Pfam:PF01562 PROSITE:PS00142 PROSITE:PS50215 Reactome:REACT_118779 GO:GO:0005737 Reactome:REACT_111102 Reactome:REACT_116125 Reactome:REACT_6900 GO:GO:0007173 GO:GO:0048011 GO:GO:0030307 GO:GO:0009986 GO:GO:0005887 GO:GO:0045121 GO:GO:0042493 GO:GO:0015629 GO:GO:0016324 GO:GO:0008284 GO:GO:0008270 GO:GO:0032496 GO:GO:0001666 GO:GO:0007219 GO:GO:0097190 GO:GO:0032722 GO:GO:0005112 GO:GO:0055099 GO:GO:0004222 GO:GO:0002446 GO:GO:0035313 TreeFam:TF314733 Gene3D:3.40.390.10 Gene3D:4.10.70.10 InterPro:IPR001762 Pfam:PF00200 SMART:SM00050 SUPFAM:SSF57552 PROSITE:PS50214 GO:GO:0051088 GO:GO:0010820 GO:GO:0030574 GO:GO:0022617 GO:GO:0007220 MEROPS:M12.217 eggNOG:NOG269976 KO:K06059 OMA:KVCCRDE OrthoDB:EOG7S4X58 EMBL:U86755 EMBL:U69611 EMBL:U69612 EMBL:U92649 RefSeq:NP_003174.3 UniGene:Hs.404914 PDB:1BKC PDB:1ZXC PDB:2A8H PDB:2DDF PDB:2FV5 PDB:2FV9 PDB:2I47 PDB:2M2F PDB:2OI0 PDB:3B92 PDB:3CKI PDB:3E8R PDB:3EDZ PDB:3EWJ PDB:3G42 PDB:3KMC PDB:3KME PDB:3L0T PDB:3L0V PDB:3LE9 PDB:3LEA PDB:3LGP PDB:3O64 PDBsum:1BKC PDBsum:1ZXC PDBsum:2A8H PDBsum:2DDF PDBsum:2FV5 PDBsum:2FV9 PDBsum:2I47 PDBsum:2M2F PDBsum:2OI0 PDBsum:3B92 PDBsum:3CKI PDBsum:3E8R PDBsum:3EDZ PDBsum:3EWJ PDBsum:3G42 PDBsum:3KMC PDBsum:3KME PDBsum:3L0T PDBsum:3L0V PDBsum:3LE9 PDBsum:3LEA PDBsum:3LGP PDBsum:3O64 ProteinModelPortal:P78536 SMR:P78536 BioGrid:112731 IntAct:P78536 MINT:MINT-108290 STRING:9606.ENSP00000309968 BindingDB:P78536 ChEMBL:CHEMBL3706 GuidetoPHARMACOLOGY:1662 PhosphoSite:P78536 DMDM:14423632 PaxDb:P78536 PRIDE:P78536 DNASU:6868 Ensembl:ENST00000310823 GeneID:6868 KEGG:hsa:6868 UCSC:uc002qzu.3 CTD:6868 GeneCards:GC02M009580 HGNC:HGNC:195 HPA:CAB025906 HPA:HPA010738 HPA:HPA051575 MIM:603639 MIM:614328 neXtProt:NX_P78536 Orphanet:294023 PharmGKB:PA24512 HOGENOM:HOG000033797 HOVERGEN:HBG050457 InParanoid:P78536 PhylomeDB:P78536 BRENDA:3.4.24.86 SignaLink:P78536 ChiTaRS:ADAM17 EvolutionaryTrace:P78536 GeneWiki:ADAM17 GenomeRNAi:6868 NextBio:26807 PRO:PR:P78536 ArrayExpress:P78536 Bgee:P78536 CleanEx:HS_ADAM17 Genevestigator:P78536 GO:GO:0030183 GO:GO:0033627 GO:GO:0035625 GO:GO:0002467 GO:GO:0060397 GO:GO:0031293 GO:GO:0032717 GO:GO:0031659 GO:GO:0030511 GO:GO:0033025 GO:GO:0048536 GO:GO:0033077 Uniprot:P78536) HSP 1 Score: 62.003 bits (149), Expect = 7.115e-9 Identity = 83/317 (26.18%), Postives = 131/317 (41.32%), Query Frame = 0
Query: 119 KYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIEN---------------ELNDEFKMDXPPSEXSTRFGDQFIENGPY---CVLNIEVDKSLYYSFDRNIQDIK-QFVFMTVMGTNKIYREA--DLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSN-----EKSSVEPKIFIEDFSFAPAPH-TDYCLSYVFSAQNFG-ATLGIAXVG--------GVXEPQIID--GDRN--YNVGFITTGGFRTQYQT---ELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEI 392
+Y IE R++++ KD +YKS D+ N+ EL + +D P E + + P C L + D Y R + ++ + + IYR D G+ IQ R+ + +PQ G + Y + EK + + K+ +E FSF A + CL+++F+ Q+F TLG+A VG GV G +N N G +T + T +L HE GH+ G+ HD G P + G +M PIA + +N++ FS CSK+ I
Sbjct: 146 EYNIEPLWRFVNDT-KDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRI-LKSPQEVKP-GEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNE-DQGGKYVMYPIAVSGDHENNKMFSNCSKQSI 458
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592771850|gb|GAXK01182718.1| (TSA: Calanus finmarchicus comp848534_c0_seq1 transcribed RNA sequence) HSP 1 Score: 126.716 bits (317), Expect = 2.916e-30 Identity = 121/425 (28.47%), Postives = 192/425 (45.18%), Query Frame = 0
Query: 12 IILFLTLYSTTIQALQ-KIEQFNKYIVLTSAQHVIVSQSDSXXXXXXXXXXDNYYELRLHKEENSFNFEMDYYVGFVVTRNRDMKEGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDV-HNIENE---LNDEFKMDXPPSEXSTRFGDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNFGATLGIAXVGGVX---EPQIIDGDR----NYNVGFITTGGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKE-----PAPLITSI 419
I L L S I A K E F+ ++ ++ +S+ D Y+L L KE++ F + FV++ + A+G + + FF G F + +YI+ + + VGK LY + DV ++ E LN F P S + G C + I VDK L +F + ++ V M N+IY+ ++ I G P QF V ++ + C + R S C S E F+E+ A H+D CL+++F++ +FG+TLG+A +G V P II + + N GFIT G + LT AHE GH++GS+HD G P GY LM+ AP + ++RFS CSK I++ + ++ R C+V++ P P + +
Sbjct: 1222 ISLILVFSSNIIDAENIKHEDFDNTVLQAGDDFILAGRSE---------VYDMDYKLILVKEDDPLIFSEEDEDIFVISHSSST--NRAFGSIKDGRFF-GQFRAGNTAFYID----HPEKVGKTGQAILYSAEDVLDDVTKEGKFLNATFNRRVPQPLIS-----RVKTKGNICRMRIIVDKYLLETFGNDKGRVRAMVKEHEMSLNEIYQ---VIEISGKPFQFKVVDIEFHDDAFC-ARNRNSVGC-KRWSQGEDDKFLEEH--AKRDHSDVCLTFLFTSHDFGSTLGVAYIGTVCSSYRPTIISNGQTAKLSANTGFITFDGKTFVPTSHLTFAHEVGHNMGSSHDGVGPTRNCPAK----GY-LMASFAPSRPTEENKRFSSCSKDSINKAVKKLLKDPLRQCMVEQDHLVKPKPTVRPV 2397
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592918193|gb|GAXK01040182.1| (TSA: Calanus finmarchicus comp147019_c0_seq2 transcribed RNA sequence) HSP 1 Score: 77.7962 bits (190), Expect = 3.304e-14 Identity = 76/240 (31.67%), Postives = 114/240 (47.50%), Query Frame = 0
Query: 171 GDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP--IQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAX------VGGVXEP--QIIDGDRNYNVGFITT---GGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVL 396
GD F + C+L ++ D Y ++ + + + V N IYR D +DG P I F++ R++V+T + SYR VE F+E FS + +CL+Y+F+ ++F G TLG+A GGV E ++ N G IT G + +T+AHE GH+ GS HD D P + G +M A +K N++RFSPCS K I++VL
Sbjct: 3299 GDYFDKRKTTCMLYLQADHLFYQKMGQSEEACIEVMTRHVQRVNSIYRAVDF-DMDGKPDNISFMIKRIKVHTQDALEDP---SYRFPG-NYGVEK--FLEIFS--EEDYDAFCLAYMFTYRDFEGGTLGLAWTGDLKNAGGVCEKNGHYRGSFKSLNTGIITLMNYGKHVPPAVSHVTMAHEMGHNFGSPHDPEADKDCVPGGED--GNYIMFARATSGDKYNNKRFSPCSLKSINKVL 3985
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592918194|gb|GAXK01040181.1| (TSA: Calanus finmarchicus comp147019_c0_seq1 transcribed RNA sequence) HSP 1 Score: 77.7962 bits (190), Expect = 3.313e-14 Identity = 76/240 (31.67%), Postives = 114/240 (47.50%), Query Frame = 0
Query: 171 GDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP--IQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAX------VGGVXEP--QIIDGDRNYNVGFITT---GGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVL 396
GD F + C+L ++ D Y ++ + + + V N IYR D +DG P I F++ R++V+T + SYR VE F+E FS + +CL+Y+F+ ++F G TLG+A GGV E ++ N G IT G + +T+AHE GH+ GS HD D P + G +M A +K N++RFSPCS K I++VL
Sbjct: 3299 GDYFDKRKTTCMLYLQADHLFYQKMGQSEEACIEVMTRHVQRVNSIYRAVDF-DMDGKPDNISFMIKRIKVHTQDALEDP---SYRFPG-NYGVEK--FLEIFS--EEDYDAFCLAYMFTYRDFEGGTLGLAWTGDLKNAGGVCEKNGHYRGSFKSLNTGIITLMNYGKHVPPAVSHVTMAHEMGHNFGSPHDPEADKDCVPGGED--GNYIMFARATSGDKYNNKRFSPCSLKSINKVL 3985
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592886356|gb|GAXK01072019.1| (TSA: Calanus finmarchicus comp551125_c0_seq1 transcribed RNA sequence) HSP 1 Score: 68.5514 bits (166), Expect = 1.798e-11 Identity = 61/235 (25.96%), Postives = 106/235 (45.11%), Query Frame = 0
Query: 177 NGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXVGGVXEPQIIDGDRNYNVG---FITTGGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQY-MEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRN 406
+G YC +++ ++ L+ ++R+ + K V + N+IY + +QF ++ + CS +S+ K + FS T+YCL Y+F+ ++F G +G+A G V + ++YN G F+ G +T LAHE GH+ G+ HD + C Y M G +L++ + + SR FS CS++ I Q L + +S N
Sbjct: 801 SGYYCNIHVVIEDGLFEMWNRDREIAKSSVTTIISNLNRIYTD---TVFQEMGLQFQAAKITIGPDV-----------CSGPITSIHSKQCLIQFS-KMTNSTEYCLHYLFTYRDFSGGHVGLAWPGVVCKDSAFT--QSYNTGLVSFLNAGWNQTLTMVSENLAHEIGHNFGAIHDEITEHCNARGYIMGESGTSLLAQTSLE-----SRSFSSCSERCIKQDLEAILNSREGN 1439
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592886355|gb|GAXK01072020.1| (TSA: Calanus finmarchicus comp551125_c0_seq2 transcribed RNA sequence) HSP 1 Score: 68.1662 bits (165), Expect = 2.179e-11 Identity = 62/235 (26.38%), Postives = 108/235 (45.96%), Query Frame = 0
Query: 177 NGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXVGGVXEPQIIDGDRNYNVG---FITTGGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQY-MEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRN 406
+G YC +++ ++ L+ ++R+ + K V + N+IY + + +QF ++ + P C S +S+ K + FS T+YCL Y+F+ ++F G +G+A G V + ++YN G F+ G +T LAHE GH+ G+ HD + C Y M G +L++ + + SR FS CS++ I Q L + +S N
Sbjct: 397 SGYYCNIHVVIEDGLFEMWNRDREIAKSSVTTIISNLNRIYTDTVFQEMG---LQFQAAKITIG-PDVC----------SGPITSIHSKQCLIQFS-KMTNSTEYCLHYLFTYRDFSGGHVGLAWPGVVCKDSAFT--QSYNTGLVSFLNAGWNQTLTMVSENLAHEIGHNFGAIHDEITEHCNARGYIMGESGTSLLAQTSLE-----SRSFSSCSERCIKQDLEAILNSREGN 1035
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592950324|gb|GAXK01008229.1| (TSA: Calanus finmarchicus comp136904_c0_seq1 transcribed RNA sequence) HSP 1 Score: 67.781 bits (164), Expect = 2.275e-11 Identity = 75/245 (30.61%), Postives = 106/245 (43.27%), Query Frame = 0
Query: 181 CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIE-DFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXVGGVXEPQIIDGDRNYNVGFIT---TGGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVK-EPAPLITSI 419
C + +D+ LY FD NI + N IY E + T D I F + R+QV SC S Y E S +IF + DFS D+CL+Y+F+ +F T G+A +G + + N GFIT G R + +TLAHE GHSLG+ HD + E G N + +A + FS CS + + L + NCLV + +PL S+
Sbjct: 422 CKVFAGIDEPLYKHFDSNISYFTDLIQTHFEAVNDIYNEK-VFTGDLSDIHFKLSRIQV-MFGSCASF---KYENCTENRSKYLEIFDQYDFS-------DFCLAYMFTYLDFHNGTAGLASIGTMCRHR-------QNSGFITLLNNGLDRPVNDSIITLAHELGHSLGAQHD-------EDVKDEDCGQNYI--MAATMNDSLVEEFSGCSARTMQDKLNMVLEDTNLNCLVTDDESPLEVSL 1072
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592860066|gb|GAXK01097496.1| (TSA: Calanus finmarchicus comp38758_c0_seq2 transcribed RNA sequence) HSP 1 Score: 67.0106 bits (162), Expect = 6.681e-11 Identity = 70/264 (26.52%), Postives = 112/264 (42.42%), Query Frame = 0
Query: 181 CVLNIEVDKSLY-------YSFDRNIQDIKQFVFMTVMGTNKIYREADLVTID----GHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFS--FAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP-----QIIDG-----DRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN--LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCL 408
C L I+ D L+ + + ++I + V N+IY + + GH F V R+++ CN + + SN I + +F + H +CL+YV + ++F G TLG+A V GG+ E + ++G R+ N G IT + + ++LTLAHE GH+ GS HD P+ G +M A ++ N+ +FSPCS K I VL + + NC
Sbjct: 890 CSLFIQTDPLLWRHVKEQELTDSKTQEEILSMIAQHVKAVNRIYGDTEFAAGKYRHTGH--TFQVNRIKILNDSDCNVKPKNPFCLSN--------IDVSNFLNLHSKTDHEHFCLAYVLTYRDFTGGTLGLAWVASASGASGGICEKYKTYTENVNGIHHTAQRSLNTGIITFVNYNARVPPKVSQLTLAHEIGHNFGSPHD------YPPECRPGGGSGNYIMFASATSGDRDNNNKFSPCSVKNISAVLDAVVDERKHNCF 1633
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592860067|gb|GAXK01097495.1| (TSA: Calanus finmarchicus comp38758_c0_seq1 transcribed RNA sequence) HSP 1 Score: 67.0106 bits (162), Expect = 6.688e-11 Identity = 70/264 (26.52%), Postives = 112/264 (42.42%), Query Frame = 0
Query: 181 CVLNIEVDKSLY-------YSFDRNIQDIKQFVFMTVMGTNKIYREADLVTID----GHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFS--FAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP-----QIIDG-----DRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN--LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCL 408
C L I+ D L+ + + ++I + V N+IY + + GH F V R+++ CN + + SN I + +F + H +CL+YV + ++F G TLG+A V GG+ E + ++G R+ N G IT + + ++LTLAHE GH+ GS HD P+ G +M A ++ N+ +FSPCS K I VL + + NC
Sbjct: 890 CSLFIQTDPLLWRHVKEQELTDSKTQEEILSMIAQHVKAVNRIYGDTEFAAGKYRHTGH--TFQVNRIKILNDSDCNVKPKNPFCLSN--------IDVSNFLNLHSKTDHEHFCLAYVLTYRDFTGGTLGLAWVASASGASGGICEKYKTYTENVNGIHHTAQRSLNTGIITFVNYNARVPPKVSQLTLAHEIGHNFGSPHD------YPPECRPGGGSGNYIMFASATSGDRDNNNKFSPCSVKNISAVLDAVVDERKHNCF 1633
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592950640|gb|GAXK01007913.1| (TSA: Calanus finmarchicus comp541507_c0_seq1 transcribed RNA sequence) HSP 1 Score: 53.9138 bits (128), Expect = 1.970e-7 Identity = 48/157 (30.57%), Postives = 75/157 (47.77%), Query Frame = 0
Query: 259 KSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIA--------XVGGVXEPQIIDGDRNYNVGFITTG--GFRTQY-------QTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLM 397
+SS + + +E FS H D+CL+++F+ F G LG+A VGG+ P+ +N ++ +G R Y + +L AHEFGH+ GS HD C P + Y LM + N+++FSPCS + I +VL+
Sbjct: 211 RSSWDVRNLLEVFS-REYTHKDFCLAHLFTDIKFEGGILGLAYVGSPRRNSVGGICTPEYF---KNGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPEC-SPSASQGGSY-LMYTYSVSGYDVNNKKFSPCSLRFIRKVLL 663
BLAST of EMLSAG00000000440 vs. C. finmarchicus
Match: gi|592873614|gb|GAXK01083948.1| (TSA: Calanus finmarchicus comp177527_c0_seq4 transcribed RNA sequence) HSP 1 Score: 55.8398 bits (133), Expect = 2.012e-7 Identity = 88/384 (22.92%), Postives = 155/384 (40.36%), Query Frame = 0
Query: 63 NYYELRLHKEENSFNFEMD---YYVGFVVTRNRDMKEGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDV-----HNIENEL-----------NDEFKMDXPPSEXSTRFGDQFIEN-------GPYCVLNIEVDKSLYYSFD-RNIQDIKQFVFMTVMGTNKIYREA---DLVTIDGHP-IQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIA--------XVGGVXEPQIIDGDRNYNVGFITTG--GFRTQY-------QTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLM 397
++ + + +EN +D +Y G V + + H E G + + DD Y++E A R+L ++ + YK SD+ EN+ N ++D + + +F N C L + D Y N + ++ + +KIY + D + G + F++ ++ V+ + G Y + +SS + + +E FS H D+CL+++F+ F G LG+A VGG+ P+ +N ++ +G R Y + +L AHEFGH+ GS HD C P + Y LM + N+++FSPCS + I +VL+
Sbjct: 492 SFKAVEIDDDENIVRVPVDRDSFYDGRVFGETKSRAQVHM-----EDGVITASIQTPDDIYHVEPAWRHLPETDEETM-IAYKESDIKLSWTQPDENQFIPPHACDFVKENGTVEVDEKEEQKRVKRSSEFNFNPGEGSLRQTRCPLLLVADYRFYKEMGGSNSKTTVNYLISLIDRVHKIYEDTVWRDTMDSGGFSGMGFIIKKIVVHRKPTTVREGEVHY--NMFRSSWDVRNLLEVFS-REYTHKDFCLAHLFTDIKFEGGILGLAYVGSPRRNSVGGICTPEYF---KNGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPEC-SPSASQGGSY-LMYTYSVSGYDVNNKKFSPCSLRFIRKVLL 1601
BLAST of EMLSAG00000000440 vs. L. salmonis peptides
Match: EMLSAP00000000440 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1068:461577:463122:-1 gene:EMLSAG00000000440 transcript:EMLSAT00000000440 description:"maker-LSalAtl2s1068-augustus-gene-3.20") HSP 1 Score: 930.243 bits (2403), Expect = 0.000e+0 Identity = 454/454 (100.00%), Postives = 454/454 (100.00%), Query Frame = 0
Query: 1 MSYTLITFGHIIILFLTLYSTTIQALQKIEQFNKYIVLTSAQHVIVSQSDSNLILNITTTNDNYYELRLHKEENSFNFEMDYYVGFVVTRNRDMKEGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIENELNDEFKMDXPPSEXSTRFGDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNFGATLGIAXVGGVXEPQIIDGDRNYNVGFITTGGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLITSIEEQKEERGGAAGPSXSVILSIFMCGILLTSCSVIY 454
MSYTLITFGHIIILFLTLYSTTIQALQKIEQFNKYIVLTSAQHVIVSQSDSNLILNITTTNDNYYELRLHKEENSFNFEMDYYVGFVVTRNRDMKEGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIENELNDEFKMDXPPSEXSTRFGDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNFGATLGIAXVGGVXEPQIIDGDRNYNVGFITTGGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLITSIEEQKEERGGAAGPSXSVILSIFMCGILLTSCSVIY
Sbjct: 1 MSYTLITFGHIIILFLTLYSTTIQALQKIEQFNKYIVLTSAQHVIVSQSDSNLILNITTTNDNYYELRLHKEENSFNFEMDYYVGFVVTRNRDMKEGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIENELNDEFKMDXPPSEXSTRFGDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNFGATLGIAXVGGVXEPQIIDGDRNYNVGFITTGGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLITSIEEQKEERGGAAGPSXSVILSIFMCGILLTSCSVIY 454
BLAST of EMLSAG00000000440 vs. L. salmonis peptides
Match: EMLSAP00000010449 (pep:novel supercontig:LSalAtl2s:LSalAtl2s691:35352:36533:-1 gene:EMLSAG00000010449 transcript:EMLSAT00000010449 description:"maker-LSalAtl2s691-augustus-gene-0.13") HSP 1 Score: 75.0998 bits (183), Expect = 6.300e-15 Identity = 73/247 (29.55%), Postives = 113/247 (45.75%), Query Frame = 0
Query: 181 CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXVGGVXEPQIIDGDRNYNVGFITT---GGFRTQYQTELTLAHEFGHSLGSAHDSFGDG--CLDPQYMEYPGYNL-MSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLITSIE 420
C L I VD+ + +N+ I++ V N+I+ + L I+F + RLQV SC+S C+ ++ + DF ++CL+Y+FS ++F G T G A VG V N N GFIT+ G R+ + +T AHE GH+ G+ HDS D C+ Y+ Y+ + P KV+ K +FS CS + + L E+ S R N K + + +E
Sbjct: 24 CNLMIGVDEPFWARHGKNMSQIEELAQEHVKVLNEIFTKQVLNESPYDDIEFRLQRLQV-MFGSCDSFENTVTNCTAQRDNFLKAFDRHDFK-------EFCLAYMFSHRDFSGGTAGYASVGTVCA-------HNSNSGFITSLNYGVDRSLEDSTITFAHEVGHNFGAKHDSDYDDSECIKRDYIMNEVYDATLHPEGEKVDYKT--QFSDCSITSMKKKLNEL--STRDNLCFKPESEVSEVVE 251
BLAST of EMLSAG00000000440 vs. L. salmonis peptides
Match: EMLSAP00000012406 (pep:novel supercontig:LSalAtl2s:LSalAtl2s909:14786:25420:-1 gene:EMLSAG00000012406 transcript:EMLSAT00000012406 description:"maker-LSalAtl2s909-augustus-gene-0.24") HSP 1 Score: 66.6254 bits (161), Expect = 6.019e-12 Identity = 97/399 (24.31%), Postives = 156/399 (39.10%), Query Frame = 0
Query: 96 EGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLD----NVGKDVVGFLYKSS--------------------------DVHNIENEL--NDEFKMDXPPSE------------------XSTRFGDQFIEN---GPYCVLNIEVDKSLYYSFDRNIQD-------IKQFVFMTVMGTNKIYREADLVTIDGHP-IQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDF--SFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP-----QIIDG-----DRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVK 410
+ + +G + E G F G D YY+E ++YL N K++ +Y S + NI+N DEF P SE +TR + I+N C L I+ D + +D I + V N IY + H QF V R++++ NS + + P I + +F + + H ++CL+YVF+ ++F G TLG+A V GG+ E + ++G R+ N G IT + ++ ++LTLAHE GH+ GS HD + + C + G +M A + N+ +FS CSK I +VL + + NC +
Sbjct: 115 KSYCFGAIRE-GIFDGQIRTKDGIYYVERIEKYLKDLPTNDTKNIHSVIYHESFMKDPLHHSRKASAMGSSCATEANRRWMENIQNSAVDKDEFVQARPNSESVEKIIMESDPRFKYTAEANTRRKKRSIDNPNNKKSCSLYIQTDPLFWNHIKEQEKDDQKTEEEILSLIAQHVKAVNLIYSDTRFNGKYKHKGYQFEVQRIKIHD----NSRCKVGVFTQDYNKFCVPNIDVSNFLNMHSKSNHEEFCLAYVFTYRDFTGGTLGLAWVASASGASGGICETYKRYTENVNGVHQMAKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD-YPEEC---RPGGQKGNFIMFASATSGDLLNNNQFSNCSKANISEVLDAISDGRKPNCFTE 504
BLAST of EMLSAG00000000440 vs. L. salmonis peptides
Match: EMLSAP00000009819 (pep:novel supercontig:LSalAtl2s:LSalAtl2s639:49543:124914:-1 gene:EMLSAG00000009819 transcript:EMLSAT00000009819 description:"maker-LSalAtl2s639-augustus-gene-1.23") HSP 1 Score: 60.077 bits (144), Expect = 8.657e-10 Identity = 49/145 (33.79%), Postives = 71/145 (48.97%), Query Frame = 0
Query: 281 YCLSYVFSAQNF-GATLGIAXVGGVXEPQIIDGDRN---------YNVGFITT---GGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEP 412
+CL+Y+F+ ++F G TLG+A G + + +RN N G IT G + +T+AHE GH+ GS HD D P + G +M A +KKN+R FSPCS K + VL + K + C +EP
Sbjct: 242 FCLAYMFTYRDFEGGTLGLAWTGDLKNAGGV-CERNGHYRGSLKSLNTGIITLLNYGKHVPPAVSHVTMAHEMGHNFGSPHDPEDDKQCVPGGED--GNYIMFARATSGDKKNNRAFSPCSLKIVKNVL-KTKAQTEKGCF-REP 381
BLAST of EMLSAG00000000440 vs. L. salmonis peptides
Match: EMLSAP00000009451 (pep:novel supercontig:LSalAtl2s:LSalAtl2s607:176320:181083:1 gene:EMLSAG00000009451 transcript:EMLSAT00000009451 description:"augustus_masked-LSalAtl2s607-processed-gene-1.1") HSP 1 Score: 58.151 bits (139), Expect = 2.470e-9 Identity = 49/158 (31.01%), Postives = 77/158 (48.73%), Query Frame = 0
Query: 258 EKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIA--------XVGGVXEPQIIDGDRNYNVGFITTG--GFRTQY-------QTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLM 397
EKSS + + +E FS + H +CL+++F+ F G LG+A VGG+ P+ +N + ++ +G R Y + +L AHEFGH+ GS HD C P + Y LM + N+++FSPCS + I +VL+
Sbjct: 149 EKSSWDVRNLLEVFSRDDS-HKHFCLAHLFTDIKFEGGILGLAYVGSPRRNSVGGICTPEYF---KNSHTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDSSEC-SPSASQGGSY-LMYTYSVSGYDINNKKFSPCSLRFIRKVLL 300
BLAST of EMLSAG00000000440 vs. SwissProt
Match: gi|341940186|sp|O35598.2|ADA10_MOUSE (RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; AltName: Full=Kuzbanian protein homolog; AltName: Full=Mammalian disintegrin-metalloprotease; AltName: CD_antigen=CD156c; Flags: Precursor) HSP 1 Score: 78.1814 bits (191), Expect = 3.770e-14 Identity = 110/448 (24.55%), Postives = 176/448 (39.29%), Query Frame = 0
Query: 46 VSQSDSNLILNITTTNDNYYELRLHKEENSFNFE---------MDYYVGFVVTRNRDMKEGHAYGVLNE-------KGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDV--------------HNIENELND------EFKMDXPPSEXSTRFGDQFIENGPY-------CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQY----MEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI-TSIEEQKEE 425
VS D L+L+ + + LR+ ++ + F+ E +DY + T GH YG G F G + +YIE A+RY+ + +Y D+ H++ + E P + + G + + C L I+ D L++ + + + + V + IY+ D I I F+V R+++NT S+EK P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G C + + G +M A +K N+ +FS CS + I QVL + R NC V+ P+ + EQ EE
Sbjct: 53 VSHEDQFLLLDFHA-HGRQFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYT-------GHIYGEEGSFSHGSVIDGRFEGFIKTRGGTFYIEPAERYIKDRILPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEGARAHPEKHAASSGPELLRKKRTTLAERNTCQLYIQTDH-LFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRN--ISFMVKRIRINTT-------------SDEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS-GTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKK----RNNCFVESGQPICGNGMVEQGEE 471
BLAST of EMLSAG00000000440 vs. SwissProt
Match: gi|29839751|sp|Q10741.1|ADA10_BOVIN (RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; AltName: Full=Kuzbanian protein homolog; AltName: Full=Mammalian disintegrin-metalloprotease; AltName: Full=Myelin-associated metalloproteinase; AltName: CD_antigen=CD156c; Flags: Precursor) HSP 1 Score: 78.1814 bits (191), Expect = 4.115e-14 Identity = 108/447 (24.16%), Postives = 179/447 (40.04%), Query Frame = 0
Query: 46 VSQSDSNLILNITTTNDNYYELRLHKEENSFNFE---------MDYYVGFVVTRNRDMKEGHAYGVLNE-------KGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDV--------------HNI-----ENELNDEFKMDXPPSEXSTRFGDQFIENGPY-------CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQY----MEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI-TSIEEQKEE 425
VS D L L+ + ++ LR+ ++ + F+ E +DY + T GH YG G F G + + +Y+E A+RY+ + +Y D+ H++ + ++ ++ P E G + + C L I+ D L++ + + + + V + IY+ D I I F+V R+++NT ++EK P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G C + + G +M A +K N+ +FS CS + I QVL + R NC V+ P+ + EQ EE
Sbjct: 53 VSHEDQFLRLDFHA-HGRHFNLRMKRDTSLFSEEFRVETSNAVLDYDTSHIYT-------GHIYGEEGSFSHGSVIDGRFEGFIQTHGGTFYVEPAERYIKDRTLPFHSVIYHEDDIKYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQTPQEKHAINGPELLRKKRTTVAEKNTCQLYIQTDH-LFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRN--ISFMVKRIRINTT-------------ADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS-GTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKK----RNNCFVESGQPICGNGMVEQGEE 470
BLAST of EMLSAG00000000440 vs. SwissProt
Match: gi|29337031|sp|O14672.1|ADA10_HUMAN (RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; AltName: Full=CDw156; AltName: Full=Kuzbanian protein homolog; AltName: Full=Mammalian disintegrin-metalloprotease; AltName: CD_antigen=CD156c; Flags: Precursor) HSP 1 Score: 78.1814 bits (191), Expect = 4.457e-14 Identity = 110/449 (24.50%), Postives = 180/449 (40.09%), Query Frame = 0
Query: 46 VSQSDSNLILNITTTNDNYYELRLHKEENSFNFE---------MDYYVGFVVTRNRDMKEGHAYGVLNE-------KGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDV--------------HNIENELNDEFKMDXPPSEXSTRFGDQFIENGP--------------YCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQY----MEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI-TSIEEQKEE 425
VS D L L+ + ++ LR+ ++ + F+ E +DY + T GH YG G F G + +Y+E A+RY+ + +Y D+ H++ + +++M E + ++ NGP C L I+ D L++ + + + + V + IY+ D I I F+V R+++NT ++EK P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G C + + G +M A +K N+ +FS CS + I QVL + R NC V+ P+ + EQ EE
Sbjct: 53 VSHEDQFLRLDFHA-HGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYT-------GHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMR-KYQM-TGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDH-LFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRN--ISFMVKRIRINTT-------------ADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS-GTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKK----RNNCFVESGQPICGNGMVEQGEE 470
BLAST of EMLSAG00000000440 vs. SwissProt
Match: gi|37096570|sp|Q10743.1|ADA10_RAT (RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; AltName: Full=Kuzbanian protein homolog; AltName: Full=Mammalian disintegrin-metalloprotease; AltName: CD_antigen=CD156c; Flags: Precursor) HSP 1 Score: 76.2554 bits (186), Expect = 1.119e-13 Identity = 81/270 (30.00%), Postives = 119/270 (44.07%), Query Frame = 0
Query: 181 CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQY----MEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI-TSIEEQKEE 425
C L I+ D + S+ I Q + V + IY+ D I I F+V R+++NT S+EK P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G C + + G +M A +K N+ +FS CS + I QVL + R NC V+ P+ + EQ EE
Sbjct: 18 CQLYIQTDHLFFKSYGTREAVIAQ-ISSHVKAIDAIYQTTDFSGIRN--ISFMVKRIRINTT-------------SDEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS-GTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKK----RNNCFVESGQPICGNGMVEQGEE 266
BLAST of EMLSAG00000000440 vs. SwissProt
Match: gi|29839752|sp|Q8JIY1.1|ADA10_XENLA (RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; AltName: Full=Kuzbanian protein homolog; Short=xKuz; Flags: Precursor) HSP 1 Score: 71.633 bits (174), Expect = 5.230e-12 Identity = 73/261 (27.97%), Postives = 114/261 (43.68%), Query Frame = 0
Query: 181 CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN-----LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI 416
C L I+ D Y + + + + V + IY+ D I I F+V R+++N S+EK P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G+ C P + G+ +M +K N+ +FS CS + I QVL + ++S C V+ P+
Sbjct: 222 CQLFIQTDHLFYKRYGETREAVIAQISSHVKAIDTIYQSTDFSGIRN--ISFMVKRIRINVT-------------SDEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICERNKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS-GNECT-PGEAKNLGFKENGNFIMYARTTSGDKLNNNKFSICSVRNISQVLDKKENS----CFVESGQPIC 461
BLAST of EMLSAG00000000440 vs. SwissProt
Match: gi|47117671|sp|Q9VAC5.2|ADA17_DROME (RecName: Full=ADAM 17-like protease; Flags: Precursor) HSP 1 Score: 64.6994 bits (156), Expect = 6.907e-10 Identity = 113/456 (24.78%), Postives = 181/456 (39.69%), Query Frame = 0
Query: 11 IIILFLTLYSTTIQALQKI----EQFNK-----YIVLTSAQHVIVSQSDSNLILNIT-TTNDNYYELRLHKEENSFNFEMDYYV------GFVVTRNRD-MKEGHAYGVLN-------EKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIENE----------------LNDEFKMDXPPSEXSTRFGDQ-----FIENGPYCVLNIEVDKSLYYSFDR-NIQDIKQFVFMTVMGTNKIYREA---DLVTIDG-HPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP--KIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIA--------XVGGVXEPQIIDGDRNYNVGFITTG--GFRTQY-------QTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVL 396
I + F L+ ALQK E F+K +V A+H S + N I + TT + L LH + + + Y VV + D G +G L E G + + ++ Y+IE + R+L KD + YK+SDV +NE L D+ D +E TR Q + C L + D + N + ++ + +KIY + D +G + FV+ ++ V++ + G Y EK V ++F ++S H D+CL+++F+ F G LG+A VGG+ P+ +N ++ +G R Y + +L AHEFGH+ GS HD C P + G LM + N+++FSPCS + I +VL
Sbjct: 14 ISVFFACLFVENCAALQKTLRHYEIFHKDDVVHRVVKRGAKH---STNPFNTIKEVEFTTLGKNFRLILHPHRDVLHSKFRAYAVDADGNETVVHMDHDSFYSGRVFGELESSVRAHIEDGTMTMSIHLPEETYHIEPSWRHLPEAKKDTM-VAYKASDVKVHKNEAGATPKTCGYIKEGLELEDKEHGDTLDNELHTREKRQSDQYEYTPTKTRCPLLLVADYRFFQEMGGGNTKTTINYLISLIDRVHKIYNDTVWQDRSDQEGFKGMGFVIKKIVVHSEPTRLRGGEAHYNMIREKWDVRNLLEVFSREYS-----HKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYF---KNGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPEC-SPSASQ-GGSFLMYTYSVSGYDVNNKKFSPCSLRSIRKVL 455
BLAST of EMLSAG00000000440 vs. SwissProt
Match: gi|14423630|sp|Q9Z1K9.1|ADA17_RAT (RecName: Full=Disintegrin and metalloproteinase domain-containing protein 17; Short=ADAM 17; AltName: Full=TNF-alpha convertase; AltName: Full=TNF-alpha-converting enzyme; AltName: CD_antigen=CD156b; Flags: Precursor) HSP 1 Score: 63.929 bits (154), Expect = 1.189e-9 Identity = 91/351 (25.93%), Postives = 143/351 (40.74%), Query Frame = 0
Query: 92 RDMKEGHAYG-----VLNEKGFFRGTFEVNDD--KYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIEN---------------ELNDEFKMDXPPSEXSTRFGDQFIENGPY---CVLNIEVDKSLYYSFDRNIQDIK-QFVFMTVMGTNKIYREA--DLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSN-----EKSSVEPKIFIEDFSFAPAPH-TDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQI-----IDGDRNYNVGFITTGGFRTQYQT---ELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEI 392
+D GH G VL G T +N D +Y IE R++++ KD +YKS D+ + EL + +D PSE R + E P C L + D Y R + ++ + + IYR D G+ +Q R+ + +PQ G R + + EK + + K+ +E FS A + CL+++F+ Q+F TLG+A VG G P+ + + N G +T + T +L HE GH+ G+ HD G P + G +M PIA + +N++ FS CSK+ I
Sbjct: 112 QDFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNIEPLWRFVNDT-KDKRMLVYKSEDIKDFSRLQSPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRI-LKSPQEVKP-GERHFNMAKSFPNEEKDAWDVKMLLEQFSLDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPGVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNE-DQGGKYVMYPIAVSGDHENNKMFSNCSKQSI 458
BLAST of EMLSAG00000000440 vs. SwissProt
Match: gi|14423632|sp|P78536.1|ADA17_HUMAN (RecName: Full=Disintegrin and metalloproteinase domain-containing protein 17; Short=ADAM 17; AltName: Full=Snake venom-like protease; AltName: Full=TNF-alpha convertase; AltName: Full=TNF-alpha-converting enzyme; AltName: CD_antigen=CD156b; Flags: Precursor) HSP 1 Score: 62.003 bits (149), Expect = 5.560e-9 Identity = 83/317 (26.18%), Postives = 131/317 (41.32%), Query Frame = 0
Query: 119 KYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIEN---------------ELNDEFKMDXPPSEXSTRFGDQFIENGPY---CVLNIEVDKSLYYSFDRNIQDIK-QFVFMTVMGTNKIYREA--DLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSN-----EKSSVEPKIFIEDFSFAPAPH-TDYCLSYVFSAQNFG-ATLGIAXVG--------GVXEPQIID--GDRN--YNVGFITTGGFRTQYQT---ELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEI 392
+Y IE R++++ KD +YKS D+ N+ EL + +D P E + + P C L + D Y R + ++ + + IYR D G+ IQ R+ + +PQ G + Y + EK + + K+ +E FSF A + CL+++F+ Q+F TLG+A VG GV G +N N G +T + T +L HE GH+ G+ HD G P + G +M PIA + +N++ FS CSK+ I
Sbjct: 146 EYNIEPLWRFVNDT-KDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRI-LKSPQEVKP-GEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNE-DQGGKYVMYPIAVSGDHENNKMFSNCSKQSI 458
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: AAX52664.1 (kuzbanian, isoform C [Drosophila melanogaster]) HSP 1 Score: 78.5666 bits (192), Expect = 1.537e-14 Identity = 78/267 (29.21%), Postives = 119/267 (44.57%), Query Frame = 0
Query: 188 DKSLYYSFD-RNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP-IQFVVGRLQVNTPQSCNST--GRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP----------QIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN---LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCL-VKEPAPLITSIEEQKEE 425
D+ Y D + ++I + V N IYR H I+F V R++++ +C ++ G + C NE V + + H+D+CL+YVF+ ++F G TLG+A V GG+ E Q R+ N G IT + ++ ++LTLAHE GH+ GS HD PQ G N +M A ++ N+ +FSPCS + I VL + + +R+C E A I E EE
Sbjct: 434 DRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFC-NEHMDVSNFLNLHSLE----DHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDY-------PQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEE 688
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: gb|KFM77108.1| (Disintegrin and metalloproteinase domain-containing protein 10, partial [Stegodyphus mimosarum]) HSP 1 Score: 77.7962 bits (190), Expect = 1.953e-14 Identity = 77/262 (29.39%), Postives = 121/262 (46.18%), Query Frame = 0
Query: 181 CVLNIEVDKSLY-----YSF-DRNI-QDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAP--HTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP----------QIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEM-KHSVRRNCLVKE 411
C L I+ D L+ Y D NI ++I V + N IY D G I+FVV R+++N + C+S +R+ P I + +F + H D+CL+Y+F+ ++F G TLG+A V GG+ E + + R+ N G IT + ++ +ELTLAHE GH+ GS HD + C P + G +M A ++ ++ +FS CS I VL + + + NC K+
Sbjct: 109 CSLYIQTDTFLWDHIRNYELSDTNIREEITSLVSQHIKAVNHIYENTDFDGFRG--IKFVVQRIKINDSRVCDSRMKRA------NPFCSPNIDVSNFLNLNSQFNHDDFCLAYIFTYRDFSGGTLGLAWVASASGASGGICEKYKSYTENIAGRQVQTKRSLNTGVITFVNYNSRVPPKVSELTLAHEIGHNFGSPHD-YPKECR-PGGAK--GNYIMYASATSGDRPHNNKFSECSIHNISAVLRAVFSNEGKENCFEKD 358
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: EFX89096.1 (hypothetical protein DAPPUDRAFT_310789 [Daphnia pulex]) HSP 1 Score: 78.1814 bits (191), Expect = 2.090e-14 Identity = 81/294 (27.55%), Postives = 125/294 (42.52%), Query Frame = 0
Query: 158 KMDXPPSEXSTRFGDQFIENG---PYCVLNIEVDKSLYYSF--------DRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPI-QFVVGRLQVNTPQSC--NSTGRRSYRCSNEKSSVEPKIFIEDFS--FAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXE------------PQIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN---LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLV 409
+ D PS+ R ++N C L I+ D L+ F D ++I + V N IY E H + +F V R++++ ++C N G + C P I + +F + H D+CL+YVF+ ++F G TLG+A V GG+ E P+ R+ N G IT + ++ ++LTLAHE GH+ GS HD P + G N +M A E+ N+ RFS CS I VL ++ ++NC
Sbjct: 265 RPDANPSDGGRRDRRSTVKNNVSRTTCSLFIQTDPLLWRHFYEAEKRNADNTRKEITSLIAQHVKAVNAIYMETKFDGKFPHRMTRFEVQRIKIDDDEACQPNYNGEENKFCL-------PNIDVSNFLNLHSQGNHEDFCLAYVFTYRDFTGGTLGLAWVASPSGASGGICERYKVYTENMSGYPRTTR--RSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDY-------PSHCRPGGQNGNYIMFASATSGERPNNSRFSNCSVGNISSVLDAIEEGKKKNCFT 542
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: ABV53679.2 (kuzbanian, isoform G [Drosophila melanogaster]) HSP 1 Score: 78.1814 bits (191), Expect = 2.157e-14 Identity = 78/267 (29.21%), Postives = 119/267 (44.57%), Query Frame = 0
Query: 188 DKSLYYSFD-RNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP-IQFVVGRLQVNTPQSCNST--GRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP----------QIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN---LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCL-VKEPAPLITSIEEQKEE 425
D+ Y D + ++I + V N IYR H I+F V R++++ +C ++ G + C NE V + + H+D+CL+YVF+ ++F G TLG+A V GG+ E Q R+ N G IT + ++ ++LTLAHE GH+ GS HD PQ G N +M A ++ N+ +FSPCS + I VL + + +R+C E A I E EE
Sbjct: 434 DRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFC-NEHMDVSNFLNLHSLE----DHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDY-------PQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEE 688
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: ABV53680.2 (kuzbanian, isoform F [Drosophila melanogaster]) HSP 1 Score: 77.7962 bits (190), Expect = 2.853e-14 Identity = 78/267 (29.21%), Postives = 119/267 (44.57%), Query Frame = 0
Query: 188 DKSLYYSFD-RNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP-IQFVVGRLQVNTPQSCNST--GRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP----------QIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN---LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCL-VKEPAPLITSIEEQKEE 425
D+ Y D + ++I + V N IYR H I+F V R++++ +C ++ G + C NE V + + H+D+CL+YVF+ ++F G TLG+A V GG+ E Q R+ N G IT + ++ ++LTLAHE GH+ GS HD PQ G N +M A ++ N+ +FSPCS + I VL + + +R+C E A I E EE
Sbjct: 434 DRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFC-NEHMDVSNFLNLHSLE----DHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDY-------PQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEE 688
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: AAN10838.1 (kuzbanian, isoform B [Drosophila melanogaster]) HSP 1 Score: 77.7962 bits (190), Expect = 3.021e-14 Identity = 78/267 (29.21%), Postives = 119/267 (44.57%), Query Frame = 0
Query: 188 DKSLYYSFD-RNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP-IQFVVGRLQVNTPQSCNST--GRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP----------QIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN---LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCL-VKEPAPLITSIEEQKEE 425
D+ Y D + ++I + V N IYR H I+F V R++++ +C ++ G + C NE V + + H+D+CL+YVF+ ++F G TLG+A V GG+ E Q R+ N G IT + ++ ++LTLAHE GH+ GS HD PQ G N +M A ++ N+ +FSPCS + I VL + + +R+C E A I E EE
Sbjct: 434 DRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFC-NEHMDVSNFLNLHSLE----DHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDY-------PQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEE 688
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: AAF53318.1 (kuzbanian, isoform A [Drosophila melanogaster]) HSP 1 Score: 77.7962 bits (190), Expect = 3.021e-14 Identity = 78/267 (29.21%), Postives = 119/267 (44.57%), Query Frame = 0
Query: 188 DKSLYYSFD-RNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP-IQFVVGRLQVNTPQSCNST--GRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP----------QIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYN---LMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCL-VKEPAPLITSIEEQKEE 425
D+ Y D + ++I + V N IYR H I+F V R++++ +C ++ G + C NE V + + H+D+CL+YVF+ ++F G TLG+A V GG+ E Q R+ N G IT + ++ ++LTLAHE GH+ GS HD PQ G N +M A ++ N+ +FSPCS + I VL + + +R+C E A I E EE
Sbjct: 434 DRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFC-NEHMDVSNFLNLHSLE----DHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDY-------PQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEE 688
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: XP_016772221.1 (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 isoform X5 [Apis mellifera]) HSP 1 Score: 73.559 bits (179), Expect = 5.681e-13 Identity = 72/260 (27.69%), Postives = 124/260 (47.69%), Query Frame = 0
Query: 174 FIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADL-VTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNE--KSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXE-----PQIIDG-----DRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLV 409
FI+ P ++ + + L++ ++ ++I + V N IYR+ I I+F V R++++ +C T +++Y N +++ F+ S H D+CL+YVF+ ++F G TLG+A V GG+ E + + G R+ N G IT + ++ ++LTLAHE GH+ GS HD F C P + G +M A ++ N+ +FS CS I VL ++ ++NC
Sbjct: 246 FIQTDP--LIWRHISEQLHHDAEKTREEILSLIAHHVTAVNYIYRDTRFDGRIKHRNIKFEVQRIKIDDDTAC--TPQQTYGEPNPFCMENIDVSNFLNLHSLGN--HEDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICERYKTYTETVGGMYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD-FPPECR-PGGLH--GNYIMFASATSGDRPNNSKFSKCSIGNISNVLDAIEDKKKKNCFT 495
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: XP_006563677.1 (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 isoform X3 [Apis mellifera]) HSP 1 Score: 73.559 bits (179), Expect = 6.094e-13 Identity = 72/260 (27.69%), Postives = 124/260 (47.69%), Query Frame = 0
Query: 174 FIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADL-VTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNE--KSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXE-----PQIIDG-----DRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLV 409
FI+ P ++ + + L++ ++ ++I + V N IYR+ I I+F V R++++ +C T +++Y N +++ F+ S H D+CL+YVF+ ++F G TLG+A V GG+ E + + G R+ N G IT + ++ ++LTLAHE GH+ GS HD F C P + G +M A ++ N+ +FS CS I VL ++ ++NC
Sbjct: 264 FIQTDP--LIWRHISEQLHHDAEKTREEILSLIAHHVTAVNYIYRDTRFDGRIKHRNIKFEVQRIKIDDDTAC--TPQQTYGEPNPFCMENIDVSNFLNLHSLGN--HEDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICERYKTYTETVGGMYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD-FPPECR-PGGLH--GNYIMFASATSGDRPNNSKFSKCSIGNISNVLDAIEDKKKKNCFT 513
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Match: XP_006563676.1 (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 isoform X1 [Apis mellifera]) HSP 1 Score: 73.559 bits (179), Expect = 6.260e-13 Identity = 72/260 (27.69%), Postives = 124/260 (47.69%), Query Frame = 0
Query: 174 FIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADL-VTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNE--KSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXE-----PQIIDG-----DRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLV 409
FI+ P ++ + + L++ ++ ++I + V N IYR+ I I+F V R++++ +C T +++Y N +++ F+ S H D+CL+YVF+ ++F G TLG+A V GG+ E + + G R+ N G IT + ++ ++LTLAHE GH+ GS HD F C P + G +M A ++ N+ +FS CS I VL ++ ++NC
Sbjct: 265 FIQTDP--LIWRHISEQLHHDAEKTREEILSLIAHHVTAVNYIYRDTRFDGRIKHRNIKFEVQRIKIDDDTAC--TPQQTYGEPNPFCMENIDVSNFLNLHSLGN--HEDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICERYKTYTETVGGMYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD-FPPECR-PGGLH--GNYIMFASATSGDRPNNSKFSKCSIGNISNVLDAIEDKKKKNCFT 514
BLAST of EMLSAG00000000440 vs. nr
Match: gi|1005483968|ref|XP_015778638.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10-like [Acropora digitifera]) HSP 1 Score: 103.605 bits (257), Expect = 3.990e-20 Identity = 124/484 (25.62%), Postives = 196/484 (40.50%), Query Frame = 0
Query: 11 IIILFLTLYSTTIQALQKIEQF-NKYIVLTSAQHVIVSQSDSNLILNITTTNDNYYELRLHKEENSFNFEM----------------DYYVGFVVTRN-RDMKEGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDVH------------NIENELNDEFKMDX---------------PPSEXSTRFGDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMT--VMGTNKIYREADLVTIDGHP---IQFVVGRLQVNTPQSCNSTGRRS---YRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXVG-------GVXEPQII--DGDR-NYNVG---FITTGGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLITS---IEEQKE 424
++ F L+++ + + + + N+Y L + Q N + + +D EL+L E+ FN + ++ G VVT + + +G +++ G F G V DD+Y++E AK++L ++ D +Y+S DVH + DE K P R +N C L + D L+ F + + M V N IY+ D V G+ IQF + R+ NT +S RS YR SN VE + + + H D CL+Y+F+ ++F G LG+A VG G+ E DG + N N G FI G +Q +++T AHE GH+ GS HDS + Y +M A +K+N+R FSPCS+ ++ V+ R C A I +EE +E
Sbjct: 10 LLTSFALLWNSALSYRRPLGDYINQYETLNYDTASLRQQH--NRVRRSSPNSDQRIELKLKTEKREFNIRLQRDTELFTHDFVAENGEFDPGKVVTGDVKGFDNSLVHGFISDDGVFEGKIHVGDDEYFVESAKQHLKDIPHDFHSVIYESRDVHYPHAYGAGCGVNDATKRWMDEVKRSAVKGKVIEMPHHSQFEPFHYRYRRATGSVDDNKLSCTLKMRADH-LFTEFMAGSNKERAMLIMANHVKAANAIYK--DTVFGPGNKAEGIQFQIQRMSANT----SSDAERSDNPYRDSN--IGVEKLLELN----SEENHDDVCLAYIFTYRDFTGGVLGLAWVGEAGNAAGGICEKGTTFRDGKKKNLNTGVVTFINYGKQVSQKVSQITFAHETGHNFGSPHDSSAECAPGGSSGNY----IMFAKATSGDKRNNRLFSPCSRTSMNNVMDVKGRCTDRKCCFVAAAEAICGNMVVEEGEE 474
BLAST of EMLSAG00000000440 vs. nr
Match: gi|974102209|ref|XP_015249892.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10-like [Cyprinodon variegatus]) HSP 1 Score: 94.7449 bits (234), Expect = 3.558e-17 Identity = 93/321 (28.97%), Postives = 141/321 (43.93%), Query Frame = 0
Query: 106 KGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDV--------------HNIENELNDEFKMDXPPSEXSTRFGDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFS----FAPAPHTDYCLSYVFSAQNFGATLGIAXVGGVXEPQII----DGDRN-----YNVGFITT---GGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVL 396
+G F GT + Y+IE RY +++ D +Y+ D+ N N L ++F + P S R E+ C+L++ D LYY ++++ + V + + N IY + D I I F + L+V T Q N+K + ++FI S ++ +YCLSY+ + +++ LG+A G I G RN N G IT G F+ Q +LTLAHE GHSLGS HD G C + G LM P A ++N+ +FSPCS K I ++L
Sbjct: 122 QGQFEGTIHTTNGTYHIEPLHRYTNSIA-DHHSIIYQEEDLVLPHMMSRTDGFCGSNHLNALTEKFSQEAPVS----RTRRTVDESKTSCLLHLHADY-LYYKKFKSVEAVVAQVALYMRAVNDIYDKTDFNGIK--LINFKIKTLRVMTTQ-------------NKKDPLN-RLFIGPESLLSLYSENNWGNYCLSYLLTNRDYSGVLGLAWEGKAGNWGGICSQYTGLRNGRMSTLNTGLITIQNYGQFQPPRQVQLTLAHELGHSLGSPHDE-GSKCGNLGSSGGKGRYLMFPHATDEVRENNDKFSPCSIKHISKIL 419
BLAST of EMLSAG00000000440 vs. nr
Match: gi|1020425740|ref|XP_016131609.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10-like [Sinocyclocheilus grahami]) HSP 1 Score: 94.3597 bits (233), Expect = 5.131e-17 Identity = 89/316 (28.16%), Postives = 140/316 (44.30%), Query Frame = 0
Query: 92 RDMKEGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDVHNIENELNDEFKMDXPPSEXSTRFGDQFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNFGATLGIAX------VGGVXEPQIIDGDRN--YNVGFITT---GGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVL 396
+D KE G + E G F G+ + +Y+E RY + D +Y DV + P S R DQ + C+L++ D Y F +++ + V + N IY +AD I+ + F V L V T + +S +++ + P+ + FS ++YCLSY+ + ++F LG+A GG+ I+ G RN +N G IT G + + LT AHE GHSLG+ HD G C + + G LM P A ++NS +FSPCS +++ +L
Sbjct: 111 KDEKESSCQGSVLE-GQFEGSITTANGTFYVEPTDRYTTS-NTDHHSIIYHEDDVVKSSPSCDPH----QIPVSRSKRKVDQ---SKTSCLLHLHADHRFYKRFG-SVEAVVAQVASYMKAVNDIYDKADFEGIE--LVNFKVKFLTVITEEDPSSPLGKTH--------IGPEKLLSLFS--EMNWSNYCLSYLLTNRDFSGVLGLAWEGKTDNWGGICSEMILKGGRNSSHNTGLITLQNYGYYLSPKHVHLTFAHELGHSLGAPHDE-GSDCGGLEITDGKGRFLMFPQASYKIEENSDKFSPCSLRQMSHIL 403
BLAST of EMLSAG00000000440 vs. nr
Match: gi|1005953714|ref|XP_015785243.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10-like [Tetranychus urticae]) HSP 1 Score: 93.2041 bits (230), Expect = 1.812e-16 Identity = 75/259 (28.96%), Postives = 121/259 (46.72%), Query Frame = 0
Query: 181 CVLNIEVDKSLYYSFDRNI-------QDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAP--HTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP----------QIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSV-RRNCL 408
C L I+ D L+ +++ ++I V + N IY A+ I G ++F+V RL++N +C+ +R ++ P I + +F + H D+CL+Y+F+ ++F G TLG+A V GG+ E + + R+ N G IT + ++ +ELTLAHE GH+ GS HD F C + G +M A E+ N+ +FSPCS + I VL + H + NC
Sbjct: 313 CSLYIQTDTYLWDHIRKDVSSDIKAREEIASLVAQHIKAVNHIYESANFQGIRG--LKFIVQRLKINESSACDDQVKR-----DQNPFCSPNIDVSNFLNLNSQFNHNDFCLAYIFTYRDFSGGTLGLAWVASTSGASGGICEKYKSYTENIHGRQVQTKRSLNTGIITFVNYNSRVPPKVSELTLAHEIGHNFGSPHD-FPPACRPGGAL---GNYIMYSSATSGERANNNKFSPCSVRNISAVLNAVFHQEGKENCF 560
BLAST of EMLSAG00000000440 vs. nr
Match: gi|1110953626|ref|XP_019217247.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 isoform X2 [Oreochromis niloticus]) HSP 1 Score: 92.8189 bits (229), Expect = 1.987e-16 Identity = 95/357 (26.61%), Postives = 151/357 (42.30%), Query Frame = 0
Query: 107 GFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDVH----------NIENELNDEFK------MDXPPSEXSTRFGDQFIENGPY-------CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCL----DPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI 416
G F G + YY+E A+RYL++ +Y D+H ++ + + K ++ PP E T Q + C L I+ D L+Y + ++ + + + V + IY+ D + I I F+V R+++NT S+E+ P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G C Q + G +M A +K N+ +FS CS + I QVL + R NC V+ P+
Sbjct: 126 GKFEGFIQSYHGTYYVEPAERYLEDKDVPFHSVIYHEDDIHYPHKYGPEGGCADSSVFERMKKYQASAVEQPPKEVHTELDTQLLRKKRMAQAEKNTCQLFIQTDH-LFYKYYKSREAVIAQISSHVKAIDAIYQGTDFMGIRN--ISFMVKRIRINTT-------------SDERDKSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS-GSECTPGESKSQDKKEKGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKK----RNNCFVESGQPIC 461
BLAST of EMLSAG00000000440 vs. nr
Match: gi|657570897|ref|XP_008288993.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10-like [Stegastes partitus]) HSP 1 Score: 91.2781 bits (225), Expect = 6.337e-16 Identity = 100/362 (27.62%), Postives = 152/362 (41.99%), Query Frame = 0
Query: 107 GFFRGTFEVNDDKYYIEDAKRYLDNVGKDVV--GFLYKSSDVH----------NIENELNDEFK------MDXPPSEXSTRFGDQFI----------ENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCL----DPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI 416
G F G + YY+E A+RYL+ GKDV +Y D+H ++ + + K M PP E T G + C L I+ D L+Y + + + + + V + IY+ D + I I F+V R+++NT S+E+ P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G C Q + G +M A +K N+ +FS CS + I QVL + R NC V+ P+
Sbjct: 126 GKFEGFIQSYHGNYYVEPAERYLE--GKDVPFHSVIYHEDDIHYPHKYGPEGGCADSSVFERMKRYQASAMQEPPKELHTEAGSNDLVLLRKKRMAQAEKNTCQLFIQTDH-LFYKYYKTREAVIAQISSHVKAIDAIYQGTDFMGIRN--ISFMVKRIRINTT-------------SDERDRSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS-GSECTPGESKSQDKKEKGNYIMYARATSGDKLNNNKFSICSVRNISQVLEKK----RSNCFVESGQPIC 464
BLAST of EMLSAG00000000440 vs. nr
Match: gi|583987986|ref|XP_006789219.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10-like [Neolamprologus brichardi]) HSP 1 Score: 90.8929 bits (224), Expect = 8.272e-16 Identity = 94/357 (26.33%), Postives = 152/357 (42.58%), Query Frame = 0
Query: 107 GFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDVH----------NIENELNDEFK------MDXPPSEXSTRFGDQFIENGPY-------CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCL----DPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI 416
G F G + YY+E A+RYL++ +Y D+H ++ + ++ K ++ PP E T Q + C L I+ D L++ + ++ + + + V + IY+ D + I I F+V R+++NT S+E+ P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G C Q + G +M A +K N+ +FS CS + I QVL + R NC V+ P+
Sbjct: 126 GKFEGFIQSYHGTYYVEPAERYLEDKDVPFHSVIYHEDDIHYPHKYGPEGGCADSSVFEKMKKYQTSVVEQPPKEVHTDLDTQLLRKKRMAQAEKNTCQLFIQTDH-LFFKYYKSREAVIAQISSHVKAIDAIYQGTDFMGIRN--ISFMVKRIRINTT-------------SDERDKSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS-GSECTPGESKSQDKKEKGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKK----RNNCFVESGQPIC 461
BLAST of EMLSAG00000000440 vs. nr
Match: gi|734632546|ref|XP_010744715.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 [Larimichthys crocea] >gi|808870991|gb|KKF20761.1| Disintegrin and metalloproteinase domain-containing protein 10 [Larimichthys crocea]) HSP 1 Score: 90.5077 bits (223), Expect = 1.060e-15 Identity = 101/364 (27.75%), Postives = 157/364 (43.13%), Query Frame = 0
Query: 107 GFFRGTFEVNDDKYYIEDAKRYLDNVGKDVV--GFLYKSSDVH----------NIENELNDEFK------MDXPPSEXSTRFGD------------QFIENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEP----KIFIEDFS--FAPAPHTDYCLSYVFSAQNFG-ATLGIAXVG-------GVXEPQIIDGD---RNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCL----DPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAPLI 416
G F G + YY+E A+RYL+ GKDV +Y D+H ++ + ++ K ++ PP E +T G Q +N C L I+ D L+Y + + + + + V + IY+ D + I I F+V R+++NT S+E+ P I +E F + H DYCL+YVF+ ++F LG+A VG G+ E + D ++ N G IT + + + +T AHE GH+ GS HDS G C Q + G +M A +K N+ +FS CS + I QVL + R NC V+ P+
Sbjct: 126 GKFEGFIQSYHGTYYVEPAERYLE--GKDVPFHSVIYHEDDIHYPHKYGPEGGCADSTVFEKMKKYQATAIEKPPKELNTEAGSNDPVLLRKKRMTQVEKN--TCQLFIQTDH-LFYKYYKTREAVIAQISSHVKAIDAIYQGTDFMGIRN--ISFMVKRIRINTT-------------SDERDKSNPFRFSNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS-GSECTPGESKSQDKKEKGNYIMYARATSGDKLNNNKFSICSVRNISQVLEKK----RSNCFVESGQPIC 464
BLAST of EMLSAG00000000440 vs. nr
Match: gi|926614186|ref|XP_013772127.1| (PREDICTED: disintegrin and metalloproteinase domain-containing protein 10-like [Limulus polyphemus]) HSP 1 Score: 90.1225 bits (222), Expect = 1.647e-15 Identity = 85/311 (27.33%), Postives = 140/311 (45.02%), Query Frame = 0
Query: 147 HNIENELNDEFKMDXPPSEXSTRFGDQFIENGPYCVLNIEVDKSLYYSFDRN-------IQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSF--APAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP----------QIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEM-KHSVRRNCLVKEPAPLI-TSIEEQKEE 425
+N N E + PP TR D+ C L I+ D L+ R+ ++I V + N+IY + + G I+FVV R+++N +C++ +R P I + +F + H ++CL+YVF+ ++F G TLG+A V GG+ E + + R+ N G IT + ++ +ELTLAHE GH+ GS HD + + C G +M A ++ N+ +FSPCS + I VL + ++ + NC +++ P I E+ EE
Sbjct: 223 NNYHNLYTREIQWRAPPRSQPTRTPDRRA-----CSLYIQTDSFLWEHVKRHESTDTKVKEEIISLVAQHINAVNRIYEDTNFNGYTG--IKFVVQRVKINDSSACDTPIKRG-----SNPYCIPNIDVSNFLNLNSQTNHDEFCLAYVFTYRDFSGGTLGLAWVASDSGASGGICEKYKSYTENIGGRQVQNKRSLNTGVITFVNYNSRVPPKVSELTLAHEIGHNFGSPHD-YPEECRPGGSR---GNYIMYASATSGDRFNNNKFSPCSVRNISAVLQAVYTNNGKENCFLEDGGPFCGNKIVEEGEE 517
BLAST of EMLSAG00000000440 vs. nr
Match: gi|195997335|ref|XP_002108536.1| (hypothetical protein TRIADDRAFT_51548 [Trichoplax adhaerens] >gi|190589312|gb|EDV29334.1| hypothetical protein TRIADDRAFT_51548 [Trichoplax adhaerens]) HSP 1 Score: 89.7373 bits (221), Expect = 1.687e-15 Identity = 103/375 (27.47%), Postives = 149/375 (39.73%), Query Frame = 0
Query: 84 VGFVVTRNRDMKEGHAYGVLNEKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDV-------------------HNIENELNDEFKMDXPPSEXSTRFGDQFIEN-----------GPY-CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADL-VTIDGHPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIA----XVGGVXEPQIIDGDRNYNVGF---ITTGGFRTQY----QTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEPAP 414
GFV D + YG L+ G F+G N Y+IE A+ Y NV D +Y +DV +I N N F + P + +F D+FI++ P C + I VD + Y R ++ V + + G N++YR D G + + GRL++NT T R Y +N S + + +TDYCL + SA+NF G LGIA G + +GF I + FR + L AHE GHS G+ HD + P+ G LM+ + ++ N+ FS CSK +I L+ K SV C P P
Sbjct: 108 TGFVA----DNVMSNVYGYLHVNGAFQGHIRYNRTHYFIEPAELYFSNVSTDQF-IIYALNDVISLKNLTSKNDEETTGRSSRSISNNANKYFDILRPNPDNRLQFDDEFIDHERIKRTANAASAPMACDILIHVDHT-YTELHRTPSNVAISVSILLQGINQLYRPIDFDGNGRGDGVNVLFGRLKINT------TSDR-YASNNPYSGTIGSSVDYILAASAENNTDYCLFFALSARNFSGGALGIAFQSPTPGDAGVCSYFGTFFHLRLGFNTGIVSNLFRRHIMPYARILLVWAHEIGHSYGADHDPADNTTCSPKKQ---GLYLMTAKSESIDLPNNDEFSICSKSQIAPHLVRGKSSV--GCFKHHPVP 464
BLAST of EMLSAG00000000440 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold38_size502422-snap-gene-4.24 (protein:Tk05881 transcript:maker-scaffold38_size502422-snap-gene-4.24-mRNA-1 annotation:"disintegrin and metalloproteinase domain-containing protein 10 isoform x3") HSP 1 Score: 75.485 bits (184), Expect = 1.165e-14 Identity = 71/264 (26.89%), Postives = 121/264 (45.83%), Query Frame = 0
Query: 181 CVLNIEVDKSLYYSF-------DRNIQDIKQFVFMTVMGTNKIYREADLVTIDG----HPIQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFS--FAPAPHTDYCLSYVFSAQNF-GATLGIAXV-------GGVXEP-----QIIDG-----DRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVK 410
C L I+ D + D+ ++I + V N+IY + DG + QF V R++++ C S+G+ + +++ P + + +F + + H ++CL+YVF+ ++F G TLG+A V GG+ E + I+G R+ N G IT + ++ ++LTLAHE GH+ GS HD + Q Y +M A ++ N+ +FS CSK I VL + + NC +
Sbjct: 303 CSLYIQTDPLFWRHVREQEGDDDKTQEEILSLIAQHVKAVNRIYSD---TPFDGKYKHNGYQFEVQRIKIHNDSQCKSSGKVT---ADQNQFCIPNVDVSNFLNLHSKSNHEEFCLAYVFTYRDFTGGTLGLAWVASASGASGGICETYKRYTENINGVHHTAKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDYPQECRPGGQAGNY----IMFASATSGDRDNNNKFSHCSKSNISAVLDAITDGRKPNCFTE 556
BLAST of EMLSAG00000000440 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold818_size92908-snap-gene-0.16 (protein:Tk10596 transcript:maker-scaffold818_size92908-snap-gene-0.16-mRNA-1 annotation:"disintegrin and metalloproteinase domain-containing protein 10") HSP 1 Score: 70.0922 bits (170), Expect = 7.005e-13 Identity = 76/244 (31.15%), Postives = 111/244 (45.49%), Query Frame = 0
Query: 181 CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP--IQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAX------VGGVXEP--QIIDGDRNYNVGFITT---GGFRTQYQTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVK 410
C+L ++ D Y I + V N IY+E D DG P I F++ R++V+T ++ YR VE F+E FS + +CL+Y+F+ ++F G TLG+A GGV E ++ N G IT G + +TLAHE GH+ GS HD + P + G +M A +KKN+R+FSPCS K + VL +K R C +
Sbjct: 708 CMLYLQADHLFYEKMGSEEATI-DVMTRHVQRVNSIYKEIDF-DQDGKPDNISFMIKRIKVHTGEALKDP---KYRFPGN-YGVE--KFLEIFS--EENYDAFCLAYMFTYRDFEGGTLGLAWTGDLKNAGGVCERNGHYRGSLKSLNTGIITLLNYGKHVPPAVSHVTLAHEMGHNFGSPHDPENNKVCVPGGED--GNYIMFARATSGDKKNNRQFSPCSLKSVKNVLT-IKARGRAGCFAE 938
BLAST of EMLSAG00000000440 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold268_size230776-snap-gene-1.28 (protein:Tk11094 transcript:maker-scaffold268_size230776-snap-gene-1.28-mRNA-1 annotation:"GD15481") HSP 1 Score: 62.003 bits (149), Expect = 1.163e-10 Identity = 63/241 (26.14%), Postives = 107/241 (44.40%), Query Frame = 0
Query: 181 CVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHP-IQFVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIAXVGGVXEPQIIDGDRNYNVGFITT---GGFRTQYQTELTLAHEFGHSLGSAHDSFGDG---CLDPQYMEYPGYNLMSPIAPKVE--KKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKE 411
C L + +D+ L+ DR+++ + V V N+++ + L G P + F + R+Q+ SC + + C++ + + F + + F D+CL+YVF+ +F T G+A VG ++ N+GF+T G RT + T HE H+ G+ HD+ + C + Y+ + VE +KNS FSPCS + L E+ R C E
Sbjct: 72 CDLLVGIDERLWEEHDRDLEALVGLVQNHVSYANQVFAQQVLTAETGFPDVYFRLARVQI-IHGSCQNF--QDQNCTSHRDEY-LRTFGDSYFF-----HDFCLAYVFTYLDFHNGTAGLAYVGTACYHHSAANIKSQNIGFVTLLNYGQNRTLEDSRRTFVHELAHNFGAKHDNEEENDKECQNQGYIMDESDLVEGENGTFVEGPEKNSEIFSPCSIAAMKAKLNEIHED--RQCYKDE 301
BLAST of EMLSAG00000000440 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold472_size162276-snap-gene-0.28 (protein:Tk12248 transcript:maker-scaffold472_size162276-snap-gene-0.28-mRNA-1 annotation:"disintegrin and metalloproteinase domain-containing protein 10") HSP 1 Score: 61.6178 bits (148), Expect = 1.945e-10 Identity = 60/243 (24.69%), Postives = 105/243 (43.21%), Query Frame = 0
Query: 176 ENGPYCVLNIEVDKSLYYSFDRNIQDIKQFVFMTVMGTNKIYREADLVTIDGHPIQFVVGRLQV--NTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNFGATL-GIAXVGGVXEPQIIDGDRNYNVGFITTGGFRTQYQ---TELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLMEMKHSVRRNCLVKEP 412
E C L + +D+ LY + R++ ++ V V N+IY ++ L+ + F + +++ + CN T +++ +FS +D+CL++V + ++F + G+A G + +N GF T Q + +TLAHE GH+ GS+HD C M G + + R FS CS++ I + L + + RRNCLV+ P
Sbjct: 61 ERDQACELLMAIDEPLYNHYQRDMANVTDLVQNLVQQLNEIY-QSTLLKDKFTSVYFRIKEIRILFDFCTECNQTQH---------------VYLREFS--KMDFSDFCLAHVLTYRDFPEGIQGLAWRGTICH-------NTWNTGFTTLLNHGLQANIPDSGVTLAHEVGHNFGSSHDE-DMHCTSDYIMSESGSSHL-----------KRDFSDCSREAIYKELAKTLGNPRRNCLVQIP 266
BLAST of EMLSAG00000000440 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold698_size109766-snap-gene-0.16 (protein:Tk05780 transcript:maker-scaffold698_size109766-snap-gene-0.16-mRNA-1 annotation:"AGAP002381-PA") HSP 1 Score: 56.9954 bits (136), Expect = 6.639e-9 Identity = 92/384 (23.96%), Postives = 155/384 (40.36%), Query Frame = 0
Query: 96 EGHAYGVLN-------EKGFFRGTFEVNDDKYYIEDAKRYLDNVGKDVVGFLYKSSDV-HNIENELNDEFKMDXPPSEXSTRFGDQFIENGPYCVLNIEVDKSL--------------YYSFDRNIQ---------DIKQ----------FVFMTVMG-----------------TNKIYREADLVTIDGHPIQ------FVVGRLQVNTPQSCNSTGRRSYRCSNEKSSVEPKIFIEDFSFAPAPHTDYCLSYVFSAQNF-GATLGIA--------XVGGVXEPQIIDGDRNYNVGFITTG--GFRTQY-------QTELTLAHEFGHSLGSAHDSFGDGCLDPQYMEYPGYNLMSPIAPKVEKKNSRRFSPCSKKEIDQVLM 397
EG +G L E G G E ++ Y+IE + R++ + D + +YK SD+ ++ ++ D FK D + D ENG ++ VDK+ Y + ++ D++Q + F + MG +KIY D V D Q F++ ++ V+ + G Y + +++S + + +E FS H D+CL+++F+ F G LG+A VGG+ P+ +N ++ +G R Y + +L AHEFGH+ GS HD C P + Y LM + N+++FSPCS + I +VL+
Sbjct: 136 EGRVFGQLKSSATVHLEDGILTGRIETPEEIYHIEPSWRHIPDDDPDAM-IVYKESDILYSWDHPNKDNFKPD--------KVCDYVHENGTAEEHHLPVDKNALSDEHGHIIESADQYDEYGHRVKRQATGELYMDLRQTRCPLLLVADYRFFSEMGGGSSKTTVNYLISLIDRVHKIYE--DTVWKDSAGGQGFSGMGFIIKKIVVHRKPTPVREGEVHY--NMDRTSWDVRNLLEVFS-REFTHKDFCLAHLFTDIKFEGGILGLAYVGSPRRNSVGGICTPEYF---KNGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDSSEC-SPSASQGGSY-LMYTYSVSGYDVNNKKFSPCSLRFIRKVLL 500 The following BLAST results are available for this feature:
BLAST of EMLSAG00000000440 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000000440 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
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BLAST of EMLSAG00000000440 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 5
BLAST of EMLSAG00000000440 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 8
BLAST of EMLSAG00000000440 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 25
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BLAST of EMLSAG00000000440 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000000440 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 5
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s1068:461577..463122- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000000440-683206 ID=EMLSAG00000000440-683206|Name=EMLSAG00000000440|organism=Lepeophtheirus salmonis|type=gene|length=1546bp|location=Sequence derived from alignment at LSalAtl2s1068:461577..463122- (Lepeophtheirus salmonis)back to top Add to Basket
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