EMLSAG00000000448, EMLSAG00000000448-683214 (gene) Lepeophtheirus salmonis
|
Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:psen2 "presenilin 2" species:7955 "Danio rerio" [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005634 "nucleus" evidence=IBA] [GO:0050435 "beta-amyloid metabolic process" evidence=IBA] [GO:0030018 "Z disc" evidence=IBA] [GO:0016324 "apical plasma membrane" evidence=IBA] [GO:0009986 "cell surface" evidence=IBA] [GO:0007220 "Notch receptor processing" evidence=IBA] [GO:0005938 "cell cortex" evidence=IBA] [GO:0004175 "endopeptidase activity" evidence=IBA] [GO:0030426 "growth cone" evidence=IBA] [GO:0006816 "calcium ion transport" evidence=IBA] [GO:0035253 "ciliary rootlet" evidence=IBA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IBA] [GO:0043025 "neuronal cell body" evidence=IBA] [GO:0030424 "axon" evidence=IBA] [GO:0043198 "dendritic shaft" evidence=IBA] [GO:0005743 "mitochondrial inner membrane" evidence=IBA] [GO:0005887 "integral component of plasma membrane" evidence=IBA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IBA] [GO:0005765 "lysosomal membrane" evidence=IBA] [GO:0045121 "membrane raft" evidence=IBA] [GO:0031594 "neuromuscular junction" evidence=IBA] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IBA] [GO:0030318 "melanocyte differentiation" evidence=IMP] [GO:0007219 "Notch signaling pathway" evidence=IEA;IMP] [GO:0061053 "somite development" evidence=IMP] [GO:0007420 "brain development" evidence=IMP] [GO:0022008 "neurogenesis" evidence=IMP] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0008233 "peptidase activity" evidence=IEA] [GO:0016787 "hydrolase activity" evidence=IEA] [GO:0006508 "proteolysis" evidence=IEA] [GO:0016020 "membrane" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] InterPro:IPR001108 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 SMART:SM00730 ZFIN:ZDB-GENE-000330-9 GO:GO:0005938 GO:GO:0005634 GO:GO:0048471 GO:GO:0030424 GO:GO:0009986 GO:GO:0007420 GO:GO:0000139 GO:GO:0005887 GO:GO:0030018 GO:GO:0022008 GO:GO:0045121 GO:GO:0005765 GO:GO:0005743 GO:GO:0005789 GO:GO:0016324 GO:GO:0043198 GO:GO:0043025 GO:GO:0004190 GO:GO:0035253 GO:GO:0031594 GO:GO:0007219 GO:GO:0042987 GO:GO:0030426 GO:GO:0004175 GO:GO:0006816 GO:GO:0050435 GO:GO:0006509 GO:GO:0007220 GO:GO:0030318 GeneTree:ENSGT00390000016593 PANTHER:PTHR10202 GO:GO:0061053 eggNOG:NOG237920 HOGENOM:HOG000240228 HOVERGEN:HBG011375 TreeFam:TF315040 OrthoDB:EOG7NGQBG MEROPS:A22.002 CTD:5664 KO:K04522 OMA:RSCQEGR EMBL:AJ271795 EMBL:AF178539 RefSeq:NP_571589.2 UniGene:Dr.81267 Ensembl:ENSDART00000006381 GeneID:58026 KEGG:dre:58026 InParanoid:Q90ZE4 NextBio:20892003 PRO:PR:Q90ZE4 Bgee:Q90ZE4 Uniprot:Q90ZE4) HSP 1 Score: 425.631 bits (1093), Expect = 9.969e-145 Identity = 223/380 (58.68%), Postives = 283/380 (74.47%), Query Frame = 0
Query: 12 DPRRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEE-EEDRGIKLGLGDFIFYSILVGKASSY-GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
D R + + EEEE + +GAK+VIMLF PVTLCM VV TI SV+ YTE+ G L+YTPF E ++ G N+ N ++++VI MT+IL++ YKY+C IHGWL LSS MLLF FS+++LGEV KTYN+ MDY TL I+WNFGVVGM+ IHWK PL LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ +++ ++GMADS++ RRR + + + P ++Q EE+ EEDRG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPISITFGL+FYF T ++ PFMD +++ Q YI
Sbjct: 63 DRERADTPDGEEEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTEKSGQRLIYTPFEEDPNSVGQRLLNSVLNTLVMISVIVFMTIILVLLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFKTYNVAMDYPTLLMIIWNFGVVGMICIHWKGPLRLQQAYLIVISALMALIFIKYLPEWSAWVILGAISIYDLIAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW-MVGMADSNNPDSAGERRRSGGGVRTQEGVESEHDAPQAGRRQYSAEEDLEEDRGVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTDNLVRPFMDSLAAHQYYI 441
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:PSEN2 "Presenilin-2" species:9606 "Homo sapiens" [GO:0000139 "Golgi membrane" evidence=IEA] [GO:0000776 "kinetochore" evidence=IDA] [GO:0001666 "response to hypoxia" evidence=IEA] [GO:0001708 "cell fate specification" evidence=IEA] [GO:0001756 "somitogenesis" evidence=IEA] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IEA] [GO:0002244 "hematopoietic progenitor cell differentiation" evidence=IEA] [GO:0002286 "T cell activation involved in immune response" evidence=IEA] [GO:0002573 "myeloid leukocyte differentiation" evidence=IEA] [GO:0004175 "endopeptidase activity" evidence=IBA] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005637 "nuclear inner membrane" evidence=IDA] [GO:0005743 "mitochondrial inner membrane" evidence=IBA] [GO:0005765 "lysosomal membrane" evidence=IBA] [GO:0005783 "endoplasmic reticulum" evidence=IDA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IDA] [GO:0005813 "centrosome" evidence=IDA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0005887 "integral component of plasma membrane" evidence=IDA] [GO:0005938 "cell cortex" evidence=IBA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IDA] [GO:0006816 "calcium ion transport" evidence=IBA] [GO:0007176 "regulation of epidermal growth factor-activated receptor activity" evidence=IEA] [GO:0007219 "Notch signaling pathway" evidence=TAS] [GO:0007220 "Notch receptor processing" evidence=IBA;TAS] [GO:0007613 "memory" evidence=IEA] [GO:0009986 "cell surface" evidence=IBA] [GO:0015031 "protein transport" evidence=IEA] [GO:0016324 "apical plasma membrane" evidence=IBA] [GO:0016485 "protein processing" evidence=IDA] [GO:0021904 "dorsal/ventral neural tube patterning" evidence=IEA] [GO:0030018 "Z disc" evidence=IBA] [GO:0030326 "embryonic limb morphogenesis" evidence=IEA] [GO:0030424 "axon" evidence=IBA] [GO:0030426 "growth cone" evidence=IBA] [GO:0030900 "forebrain development" evidence=IEA] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=TAS] [GO:0031333 "negative regulation of protein complex assembly" evidence=IEA] [GO:0031594 "neuromuscular junction" evidence=IBA] [GO:0032091 "negative regulation of protein binding" evidence=IEA] [GO:0032469 "endoplasmic reticulum calcium ion homeostasis" evidence=IEA] [GO:0035253 "ciliary rootlet" evidence=IBA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0040011 "locomotion" evidence=IEA] [GO:0042640 "anagen" evidence=IEA] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IBA;TAS] [GO:0043025 "neuronal cell body" evidence=IBA] [GO:0043065 "positive regulation of apoptotic process" evidence=TAS] [GO:0043085 "positive regulation of catalytic activity" evidence=IDA] [GO:0043198 "dendritic shaft" evidence=IBA] [GO:0043234 "protein complex" evidence=IDA] [GO:0045121 "membrane raft" evidence=IBA] [GO:0048011 "neurotrophin TRK receptor signaling pathway" evidence=TAS] [GO:0048167 "regulation of synaptic plasticity" evidence=IEA] [GO:0048286 "lung alveolus development" evidence=IEA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IBA] [GO:0048538 "thymus development" evidence=IEA] [GO:0048854 "brain morphogenesis" evidence=IEA] [GO:0050435 "beta-amyloid metabolic process" evidence=IBA] [GO:0050820 "positive regulation of coagulation" evidence=IEA] [GO:0050852 "T cell receptor signaling pathway" evidence=IEA] [GO:0060048 "cardiac muscle contraction" evidence=IEA] [GO:0097190 "apoptotic signaling pathway" evidence=TAS] [GO:1902042 "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] [GO:1902043 "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] Reactome:REACT_691 InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 GO:GO:0005783 GO:GO:0005829 GO:GO:0005938 GO:GO:0001708 GO:GO:0005794 GO:GO:0048471 GO:GO:0043085 Reactome:REACT_111102 Reactome:REACT_116125 GO:GO:0048011 GO:GO:0030424 GO:GO:0048167 GO:GO:0009986 GO:GO:0000139 GO:GO:0005887 GO:GO:0030018 GO:GO:0000776 GO:GO:0005813 GO:GO:0045121 GO:GO:0005765 GO:GO:0050852 GO:GO:0005743 GO:GO:0005789 GO:GO:0035556 GO:GO:0031333 GO:GO:0015031 GO:GO:0016324 GO:GO:0043198 GO:GO:0043025 GO:GO:0007613 GO:GO:0004190 GO:GO:0001666 GO:GO:0035253 GO:GO:0031594 GO:GO:0030900 GO:GO:0007176 GO:GO:0007219 Orphanet:1020 GO:GO:0097190 GO:GO:0043065 GO:GO:0048286 EMBL:CH471098 Orphanet:154 GO:GO:0042987 GO:GO:0030426 GO:GO:0001756 GO:GO:0030326 GO:GO:0004175 GO:GO:0040011 GO:GO:0006816 GO:GO:0050435 GO:GO:0060048 GO:GO:0006509 GO:GO:0007220 GO:GO:0031293 GO:GO:0032091 GO:GO:0048538 GO:GO:0042640 GO:GO:0016485 ChEMBL:CHEMBL2094135 GO:GO:1902043 GO:GO:1902042 GO:GO:0001933 GO:GO:0005637 GO:GO:0032469 GO:GO:0048854 GO:GO:0021904 GO:GO:0002286 GO:GO:0002244 GO:GO:0002573 PANTHER:PTHR10202 GO:GO:0050820 eggNOG:NOG237920 HOGENOM:HOG000240228 HOVERGEN:HBG011375 TreeFam:TF315040 MEROPS:A22.002 CTD:5664 KO:K04522 EMBL:L43964 EMBL:L44577 EMBL:U34349 EMBL:U50871 EMBL:BT006984 EMBL:AK292299 EMBL:AL391628 EMBL:BC006365 EMBL:AF416718 PIR:A56993 PIR:I39174 RefSeq:NP_000438.2 RefSeq:NP_036618.2 RefSeq:XP_005273255.1 RefSeq:XP_005273256.1 UniGene:Hs.25363 ProteinModelPortal:P49810 SMR:P49810 BioGrid:111643 IntAct:P49810 MINT:MINT-95242 STRING:9606.ENSP00000355747 BindingDB:P49810 TCDB:1.A.54.1.2 PhosphoSite:P49810 DMDM:1709858 PaxDb:P49810 PRIDE:P49810 DNASU:5664 Ensembl:ENST00000366783 Ensembl:ENST00000422240 GeneID:5664 KEGG:hsa:5664 UCSC:uc009xeo.1 UCSC:uc009xep.1 GeneCards:GC01P227058 HGNC:HGNC:9509 HPA:CAB013634 HPA:HPA038005 MIM:600759 MIM:606889 MIM:613697 neXtProt:NX_P49810 PharmGKB:PA33856 InParanoid:P49810 PhylomeDB:P49810 SignaLink:P49810 ChiTaRS:PSEN2 GeneWiki:PSEN2 GenomeRNAi:5664 NextBio:22010 PRO:PR:P49810 ArrayExpress:P49810 Bgee:P49810 CleanEx:HS_PSEN2 Genevestigator:P49810 Uniprot:P49810) HSP 1 Score: 406.371 bits (1043), Expect = 5.182e-137 Identity = 233/403 (57.82%), Postives = 286/403 (70.97%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S E EE DP R + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E+ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 SQENEEDGEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:PSEN2 "Presenilin-2 CTF subunit" species:9606 "Homo sapiens" [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 GO:GO:0016021 GO:GO:0008152 GO:GO:0035556 GO:GO:0004190 EMBL:CH471098 PANTHER:PTHR10202 OMA:RSCQEGR EMBL:AL391628 UniGene:Hs.25363 HGNC:HGNC:9509 ChiTaRS:PSEN2 EMBL:AL359732 ProteinModelPortal:B1AP22 SMR:B1AP22 PRIDE:B1AP22 Ensembl:ENST00000366782 Ensembl:ENST00000391872 NextBio:35466859 ArrayExpress:B1AP22 Uniprot:B1AP22) HSP 1 Score: 406.371 bits (1043), Expect = 1.415e-136 Identity = 233/403 (57.82%), Postives = 286/403 (70.97%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S E EE DP R + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E+ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 82 SQENEEDGEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 481
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:PSEN2 "Presenilin-2" species:9823 "Sus scrofa" [GO:0000139 "Golgi membrane" evidence=IEA] [GO:0000776 "kinetochore" evidence=IEA] [GO:0001708 "cell fate specification" evidence=IEA] [GO:0001756 "somitogenesis" evidence=IEA] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IEA] [GO:0002244 "hematopoietic progenitor cell differentiation" evidence=IEA] [GO:0002286 "T cell activation involved in immune response" evidence=IEA] [GO:0002573 "myeloid leukocyte differentiation" evidence=IEA] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005637 "nuclear inner membrane" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0005813 "centrosome" evidence=IEA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA] [GO:0006816 "calcium ion transport" evidence=IEA] [GO:0007176 "regulation of epidermal growth factor-activated receptor activity" evidence=IEA] [GO:0007219 "Notch signaling pathway" evidence=IEA] [GO:0007613 "memory" evidence=IEA] [GO:0015031 "protein transport" evidence=IEA] [GO:0021904 "dorsal/ventral neural tube patterning" evidence=IEA] [GO:0030018 "Z disc" evidence=IEA] [GO:0030326 "embryonic limb morphogenesis" evidence=IEA] [GO:0030900 "forebrain development" evidence=IEA] [GO:0031333 "negative regulation of protein complex assembly" evidence=IEA] [GO:0032091 "negative regulation of protein binding" evidence=IEA] [GO:0032469 "endoplasmic reticulum calcium ion homeostasis" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0040011 "locomotion" evidence=IEA] [GO:0042640 "anagen" evidence=IEA] [GO:0043025 "neuronal cell body" evidence=IEA] [GO:0043065 "positive regulation of apoptotic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] [GO:0044267 "cellular protein metabolic process" evidence=IEA] [GO:0048167 "regulation of synaptic plasticity" evidence=IEA] [GO:0048286 "lung alveolus development" evidence=IEA] [GO:0048538 "thymus development" evidence=IEA] [GO:0048854 "brain morphogenesis" evidence=IEA] [GO:0050435 "beta-amyloid metabolic process" evidence=IEA] [GO:0050820 "positive regulation of coagulation" evidence=IEA] [GO:0050852 "T cell receptor signaling pathway" evidence=IEA] [GO:0060048 "cardiac muscle contraction" evidence=IEA] [GO:1902042 "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] [GO:1902043 "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 GO:GO:0005829 GO:GO:0001708 GO:GO:0043085 GO:GO:0048167 GO:GO:0000139 GO:GO:0005887 GO:GO:0030018 GO:GO:0044267 GO:GO:0000776 GO:GO:0005813 GO:GO:0050852 GO:GO:0005789 GO:GO:0035556 GO:GO:0031333 GO:GO:0015031 GO:GO:0043025 GO:GO:0007613 GO:GO:0004190 GO:GO:0030900 GO:GO:0007176 GO:GO:0007219 GO:GO:0043065 GO:GO:0048286 GO:GO:0001756 GO:GO:0030326 GO:GO:0040011 GO:GO:0006816 GO:GO:0050435 GO:GO:0060048 GO:GO:0006509 GO:GO:0032091 GO:GO:0048538 GO:GO:0042640 GO:GO:0016485 GO:GO:1902043 GO:GO:1902042 GO:GO:0001933 GO:GO:0005637 GO:GO:0032469 GO:GO:0048854 GO:GO:0021904 GO:GO:0002286 GO:GO:0002244 GO:GO:0002573 GeneTree:ENSGT00390000016593 PANTHER:PTHR10202 GO:GO:0050820 eggNOG:NOG237920 HOGENOM:HOG000240228 HOVERGEN:HBG011375 TreeFam:TF315040 OrthoDB:EOG7NGQBG MEROPS:A22.002 CTD:5664 KO:K04522 OMA:RSCQEGR EMBL:DQ853415 EMBL:EU287432 RefSeq:NP_001072134.1 RefSeq:XP_005668005.1 RefSeq:XP_005668006.1 UniGene:Ssc.54979 STRING:9823.ENSSSCP00000011578 Ensembl:ENSSSCT00000011882 GeneID:780410 KEGG:ssc:780410 Uniprot:Q0MS45) HSP 1 Score: 404.06 bits (1037), Expect = 3.420e-136 Identity = 232/403 (57.57%), Postives = 285/403 (70.72%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S + EE DP R + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E+ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 SQDSEEDHEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLITSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:PSEN2 "Presenilin-2" species:9031 "Gallus gallus" [GO:0000776 "kinetochore" evidence=IEA] [GO:0001708 "cell fate specification" evidence=IEA] [GO:0001756 "somitogenesis" evidence=IEA] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IEA] [GO:0002244 "hematopoietic progenitor cell differentiation" evidence=IEA] [GO:0002286 "T cell activation involved in immune response" evidence=IEA] [GO:0002573 "myeloid leukocyte differentiation" evidence=IEA] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005637 "nuclear inner membrane" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005813 "centrosome" evidence=IEA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA] [GO:0006816 "calcium ion transport" evidence=IEA] [GO:0007176 "regulation of epidermal growth factor-activated receptor activity" evidence=IEA] [GO:0007219 "Notch signaling pathway" evidence=IEA] [GO:0007613 "memory" evidence=IEA] [GO:0015031 "protein transport" evidence=IEA] [GO:0021904 "dorsal/ventral neural tube patterning" evidence=IEA] [GO:0030018 "Z disc" evidence=IEA] [GO:0030326 "embryonic limb morphogenesis" evidence=IEA] [GO:0030900 "forebrain development" evidence=IEA] [GO:0031333 "negative regulation of protein complex assembly" evidence=IEA] [GO:0032091 "negative regulation of protein binding" evidence=IEA] [GO:0032469 "endoplasmic reticulum calcium ion homeostasis" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0040011 "locomotion" evidence=IEA] [GO:0042640 "anagen" evidence=IEA] [GO:0043025 "neuronal cell body" evidence=IEA] [GO:0043065 "positive regulation of apoptotic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] [GO:0044267 "cellular protein metabolic process" evidence=IEA] [GO:0048167 "regulation of synaptic plasticity" evidence=IEA] [GO:0048286 "lung alveolus development" evidence=IEA] [GO:0048538 "thymus development" evidence=IEA] [GO:0048854 "brain morphogenesis" evidence=IEA] [GO:0050435 "beta-amyloid metabolic process" evidence=IEA] [GO:0050820 "positive regulation of coagulation" evidence=IEA] [GO:0050852 "T cell receptor signaling pathway" evidence=IEA] [GO:0060048 "cardiac muscle contraction" evidence=IEA] [GO:1902042 "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] [GO:1902043 "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 GO:GO:0016021 GO:GO:0008152 GO:GO:0035556 GO:GO:0004190 GeneTree:ENSGT00390000016593 PANTHER:PTHR10202 OrthoDB:EOG7NGQBG EMBL:AADN03003618 Ensembl:ENSGALT00000014765 Uniprot:F1NGP7) HSP 1 Score: 402.519 bits (1033), Expect = 1.774e-135 Identity = 224/375 (59.73%), Postives = 278/375 (74.13%), Query Frame = 0
Query: 29 NHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRR------RDNQRMAAESQXQEL---SPPPLQQQQQPPVE---EEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMTV L++ YKY+C IHGWL LSSFMLLFLF+YI+LGEVLKTYN+ MDY T+ I+WNFG VGM+ IHWK PL LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA + K +++ R+N + S Q L SP P P+ EEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 88 KYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFSEDTPSVGQRLLNSVLNTIIMISVIVVMTVFLVVLYKYRCYKFIHGWLILSSFMLLFLFTYIYLGEVLKTYNVAMDYPTVILIIWNFGAVGMICIHWKGPLQLQQAYLIMISALMALVFIKYLPEWSAWVILGAISIYDLIAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMIWTV-GMAKPDTAAKGQSQQTWDADERENHSSTSHSDSQILDTRSPAPSH-----PITLEEMEEEERGVKLGLGDFIFYSVLVGKAAATPSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 455
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:PSEN2 "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0000776 "kinetochore" evidence=IEA] [GO:0001708 "cell fate specification" evidence=IEA] [GO:0001756 "somitogenesis" evidence=IEA] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IEA] [GO:0002244 "hematopoietic progenitor cell differentiation" evidence=IEA] [GO:0002286 "T cell activation involved in immune response" evidence=IEA] [GO:0002573 "myeloid leukocyte differentiation" evidence=IEA] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005637 "nuclear inner membrane" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005813 "centrosome" evidence=IEA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA] [GO:0006816 "calcium ion transport" evidence=IEA] [GO:0007176 "regulation of epidermal growth factor-activated receptor activity" evidence=IEA] [GO:0007219 "Notch signaling pathway" evidence=IEA] [GO:0007613 "memory" evidence=IEA] [GO:0015031 "protein transport" evidence=IEA] [GO:0021904 "dorsal/ventral neural tube patterning" evidence=IEA] [GO:0030018 "Z disc" evidence=IEA] [GO:0030326 "embryonic limb morphogenesis" evidence=IEA] [GO:0030900 "forebrain development" evidence=IEA] [GO:0031333 "negative regulation of protein complex assembly" evidence=IEA] [GO:0032091 "negative regulation of protein binding" evidence=IEA] [GO:0032469 "endoplasmic reticulum calcium ion homeostasis" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0040011 "locomotion" evidence=IEA] [GO:0042640 "anagen" evidence=IEA] [GO:0043025 "neuronal cell body" evidence=IEA] [GO:0043065 "positive regulation of apoptotic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] [GO:0044267 "cellular protein metabolic process" evidence=IEA] [GO:0048167 "regulation of synaptic plasticity" evidence=IEA] [GO:0048286 "lung alveolus development" evidence=IEA] [GO:0048538 "thymus development" evidence=IEA] [GO:0048854 "brain morphogenesis" evidence=IEA] [GO:0050435 "beta-amyloid metabolic process" evidence=IEA] [GO:0050820 "positive regulation of coagulation" evidence=IEA] [GO:0050852 "T cell receptor signaling pathway" evidence=IEA] [GO:0060048 "cardiac muscle contraction" evidence=IEA] [GO:1902042 "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] [GO:1902043 "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 GO:GO:0005783 GO:GO:0005829 GO:GO:0001708 GO:GO:0005794 GO:GO:0043085 GO:GO:0048167 GO:GO:0005887 GO:GO:0030018 GO:GO:0044267 GO:GO:0000776 GO:GO:0005813 GO:GO:0050852 GO:GO:0035556 GO:GO:0031333 GO:GO:0015031 GO:GO:0043025 GO:GO:0007613 GO:GO:0004190 GO:GO:0030900 GO:GO:0007176 GO:GO:0007219 GO:GO:0043065 GO:GO:0048286 GO:GO:0001756 GO:GO:0030326 GO:GO:0040011 GO:GO:0006816 GO:GO:0050435 GO:GO:0060048 GO:GO:0006509 GO:GO:0032091 GO:GO:0048538 GO:GO:0042640 GO:GO:0016485 GO:GO:1902043 GO:GO:1902042 GO:GO:0001933 GO:GO:0005637 GO:GO:0032469 GO:GO:0048854 GO:GO:0021904 GO:GO:0002286 GO:GO:0002244 GO:GO:0002573 GeneTree:ENSGT00390000016593 PANTHER:PTHR10202 GO:GO:0050820 TreeFam:TF315040 OrthoDB:EOG7NGQBG CTD:5664 KO:K04522 OMA:RSCQEGR EMBL:AAEX03005265 EMBL:AAEX03005266 RefSeq:XP_547503.3 UniGene:Cfa.9548 Ensembl:ENSCAFT00000025451 GeneID:490382 KEGG:cfa:490382 Uniprot:F1PWY2) HSP 1 Score: 400.979 bits (1029), Expect = 6.252e-135 Identity = 225/376 (59.84%), Postives = 277/376 (73.67%), Query Frame = 0
Query: 23 EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI MT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E+ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 76 EEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPGYPG-DELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:PSEN2 "Presenilin-2" species:9913 "Bos taurus" [GO:0000139 "Golgi membrane" evidence=IEA] [GO:0000776 "kinetochore" evidence=IEA] [GO:0001708 "cell fate specification" evidence=IEA] [GO:0001756 "somitogenesis" evidence=IEA] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IEA] [GO:0002244 "hematopoietic progenitor cell differentiation" evidence=IEA] [GO:0002286 "T cell activation involved in immune response" evidence=IEA] [GO:0002573 "myeloid leukocyte differentiation" evidence=IEA] [GO:0004175 "endopeptidase activity" evidence=IBA] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005634 "nucleus" evidence=IBA] [GO:0005637 "nuclear inner membrane" evidence=IEA] [GO:0005743 "mitochondrial inner membrane" evidence=IBA] [GO:0005765 "lysosomal membrane" evidence=IBA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0005813 "centrosome" evidence=IEA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IBA] [GO:0005938 "cell cortex" evidence=IBA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IBA] [GO:0006816 "calcium ion transport" evidence=IBA] [GO:0007176 "regulation of epidermal growth factor-activated receptor activity" evidence=IEA] [GO:0007219 "Notch signaling pathway" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=IBA] [GO:0007613 "memory" evidence=IEA] [GO:0009986 "cell surface" evidence=IBA] [GO:0015031 "protein transport" evidence=IEA] [GO:0016324 "apical plasma membrane" evidence=IBA] [GO:0021904 "dorsal/ventral neural tube patterning" evidence=IEA] [GO:0030018 "Z disc" evidence=IBA] [GO:0030326 "embryonic limb morphogenesis" evidence=IEA] [GO:0030424 "axon" evidence=IBA] [GO:0030426 "growth cone" evidence=IBA] [GO:0030900 "forebrain development" evidence=IEA] [GO:0031333 "negative regulation of protein complex assembly" evidence=IEA] [GO:0031594 "neuromuscular junction" evidence=IBA] [GO:0032091 "negative regulation of protein binding" evidence=IEA] [GO:0032469 "endoplasmic reticulum calcium ion homeostasis" evidence=IEA] [GO:0035253 "ciliary rootlet" evidence=IBA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0040011 "locomotion" evidence=IEA] [GO:0042640 "anagen" evidence=IEA] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IBA] [GO:0043025 "neuronal cell body" evidence=IBA] [GO:0043065 "positive regulation of apoptotic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] [GO:0043198 "dendritic shaft" evidence=IBA] [GO:0045121 "membrane raft" evidence=IBA] [GO:0048167 "regulation of synaptic plasticity" evidence=IEA] [GO:0048286 "lung alveolus development" evidence=IEA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IBA] [GO:0048538 "thymus development" evidence=IEA] [GO:0048854 "brain morphogenesis" evidence=IEA] [GO:0050435 "beta-amyloid metabolic process" evidence=IBA] [GO:0050820 "positive regulation of coagulation" evidence=IEA] [GO:0050852 "T cell receptor signaling pathway" evidence=IEA] [GO:0060048 "cardiac muscle contraction" evidence=IEA] [GO:1902042 "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] [GO:1902043 "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 GO:GO:0005829 GO:GO:0005938 GO:GO:0005634 GO:GO:0001708 GO:GO:0048471 GO:GO:0043085 GO:GO:0030424 GO:GO:0048167 GO:GO:0009986 GO:GO:0000139 GO:GO:0005887 GO:GO:0030018 GO:GO:0000776 GO:GO:0005813 GO:GO:0045121 GO:GO:0005765 GO:GO:0050852 GO:GO:0005743 GO:GO:0005789 GO:GO:0035556 GO:GO:0031333 GO:GO:0015031 GO:GO:0016324 GO:GO:0043198 GO:GO:0043025 GO:GO:0007613 GO:GO:0004190 GO:GO:0035253 GO:GO:0031594 GO:GO:0030900 GO:GO:0007176 GO:GO:0007219 GO:GO:0043065 GO:GO:0048286 GO:GO:0042987 GO:GO:0030426 GO:GO:0001756 GO:GO:0030326 GO:GO:0004175 GO:GO:0040011 GO:GO:0006816 GO:GO:0050435 GO:GO:0060048 GO:GO:0006509 GO:GO:0007220 GO:GO:0032091 GO:GO:0048538 GO:GO:0042640 GO:GO:0016485 GO:GO:1902043 GO:GO:1902042 GO:GO:0001933 GO:GO:0005637 GO:GO:0032469 GO:GO:0048854 GO:GO:0021904 GO:GO:0002286 GO:GO:0002244 GO:GO:0002573 GeneTree:ENSGT00390000016593 PANTHER:PTHR10202 GO:GO:0050820 eggNOG:NOG237920 HOGENOM:HOG000240228 HOVERGEN:HBG011375 TreeFam:TF315040 OrthoDB:EOG7NGQBG EMBL:AF038937 EMBL:BC112811 RefSeq:NP_776865.2 RefSeq:XP_005216851.1 UniGene:Bt.41904 MEROPS:A22.002 PRIDE:Q9XT96 Ensembl:ENSBTAT00000017565 GeneID:282010 KEGG:bta:282010 CTD:5664 InParanoid:Q9XT96 KO:K04522 OMA:RSCQEGR NextBio:20805877 Uniprot:Q9XT96) HSP 1 Score: 399.823 bits (1026), Expect = 1.588e-134 Identity = 224/376 (59.57%), Postives = 277/376 (73.67%), Query Frame = 0
Query: 23 EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI MT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E ++ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 77 EEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFSEDTPSVGQRLLNSVLNTLIMISVIVTMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPDVFEPPLPGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 449
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:Psen2 "presenilin 2" species:10090 "Mus musculus" [GO:0000122 "negative regulation of transcription from RNA polymerase II promoter" evidence=IMP] [GO:0000776 "kinetochore" evidence=ISO] [GO:0001708 "cell fate specification" evidence=IGI] [GO:0001756 "somitogenesis" evidence=IGI] [GO:0001921 "positive regulation of receptor recycling" evidence=IMP] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IGI] [GO:0001942 "hair follicle development" evidence=IGI] [GO:0002244 "hematopoietic progenitor cell differentiation" evidence=IGI] [GO:0002286 "T cell activation involved in immune response" evidence=IGI] [GO:0002573 "myeloid leukocyte differentiation" evidence=IGI] [GO:0004175 "endopeptidase activity" evidence=IGI;IMP] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005634 "nucleus" evidence=IBA] [GO:0005637 "nuclear inner membrane" evidence=ISO] [GO:0005743 "mitochondrial inner membrane" evidence=IBA] [GO:0005765 "lysosomal membrane" evidence=IBA] [GO:0005783 "endoplasmic reticulum" evidence=ISO;IGI;IDA] [GO:0005794 "Golgi apparatus" evidence=ISO] [GO:0005813 "centrosome" evidence=ISO] [GO:0005829 "cytosol" evidence=IDA] [GO:0005887 "integral component of plasma membrane" evidence=ISO;IBA] [GO:0005938 "cell cortex" evidence=IBA] [GO:0006508 "proteolysis" evidence=IGI] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=ISO;IBA] [GO:0006816 "calcium ion transport" evidence=IPI] [GO:0007175 "negative regulation of epidermal growth factor-activated receptor activity" evidence=IMP] [GO:0007176 "regulation of epidermal growth factor-activated receptor activity" evidence=IGI] [GO:0007219 "Notch signaling pathway" evidence=IGI] [GO:0007220 "Notch receptor processing" evidence=IBA] [GO:0007611 "learning or memory" evidence=IGI] [GO:0007613 "memory" evidence=IGI] [GO:0008233 "peptidase activity" evidence=IEA] [GO:0009790 "embryo development" evidence=IGI] [GO:0009986 "cell surface" evidence=IBA] [GO:0015031 "protein transport" evidence=IGI] [GO:0016020 "membrane" evidence=IDA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016324 "apical plasma membrane" evidence=IBA] [GO:0016485 "protein processing" evidence=ISO;IGI] [GO:0016787 "hydrolase activity" evidence=IEA] [GO:0021904 "dorsal/ventral neural tube patterning" evidence=IGI] [GO:0030018 "Z disc" evidence=IDA] [GO:0030326 "embryonic limb morphogenesis" evidence=IGI] [GO:0030424 "axon" evidence=IBA] [GO:0030426 "growth cone" evidence=IBA] [GO:0030900 "forebrain development" evidence=IGI] [GO:0031333 "negative regulation of protein complex assembly" evidence=IDA] [GO:0031594 "neuromuscular junction" evidence=IBA] [GO:0032091 "negative regulation of protein binding" evidence=IDA] [GO:0032436 "positive regulation of proteasomal ubiquitin-dependent protein catabolic process" evidence=IMP] [GO:0032469 "endoplasmic reticulum calcium ion homeostasis" evidence=IGI] [GO:0035253 "ciliary rootlet" evidence=IBA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0036064 "ciliary basal body" evidence=IDA] [GO:0040011 "locomotion" evidence=IGI] [GO:0042640 "anagen" evidence=IGI] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IBA] [GO:0043025 "neuronal cell body" evidence=IDA] [GO:0043065 "positive regulation of apoptotic process" evidence=IGI] [GO:0043066 "negative regulation of apoptotic process" evidence=IBA] [GO:0043085 "positive regulation of catalytic activity" evidence=ISO] [GO:0043198 "dendritic shaft" evidence=IBA] [GO:0043234 "protein complex" evidence=ISO] [GO:0043393 "regulation of protein binding" evidence=IGI] [GO:0043589 "skin morphogenesis" evidence=IMP] [GO:0044267 "cellular protein metabolic process" evidence=IGI] [GO:0045121 "membrane raft" evidence=IBA] [GO:0048167 "regulation of synaptic plasticity" evidence=IGI] [GO:0048286 "lung alveolus development" evidence=IMP] [GO:0048471 "perinuclear region of cytoplasm" evidence=IBA] [GO:0048538 "thymus development" evidence=IGI] [GO:0048854 "brain morphogenesis" evidence=IGI] [GO:0050435 "beta-amyloid metabolic process" evidence=IMP;IDA] [GO:0050820 "positive regulation of coagulation" evidence=IMP] [GO:0050852 "T cell receptor signaling pathway" evidence=IGI] [GO:0051444 "negative regulation of ubiquitin-protein ligase activity" evidence=IMP] [GO:0051604 "protein maturation" evidence=IGI] [GO:0060048 "cardiac muscle contraction" evidence=IMP] [GO:1902042 "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IDA] [GO:1902043 "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IDA] [GO:2000059 "negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process" evidence=IMP] [GO:2001234 "negative regulation of apoptotic signaling pathway" evidence=IGI] Reactome:REACT_99294 InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 MGI:MGI:109284 GO:GO:0005783 GO:GO:0005829 GO:GO:0005938 GO:GO:0005634 GO:GO:0001708 GO:GO:0005794 GO:GO:0048471 GO:GO:0043085 GO:GO:0030424 GO:GO:0048167 GO:GO:0043066 GO:GO:0009986 GO:GO:0000139 GO:GO:0005887 GO:GO:0030018 GO:GO:0045121 GO:GO:0005765 GO:GO:0050852 GO:GO:0005743 GO:GO:0005789 GO:GO:0035556 GO:GO:0031333 GO:GO:0015031 GO:GO:0016324 GO:GO:0043198 GO:GO:0043025 GO:GO:0007613 GO:GO:0004190 GO:GO:0035253 GO:GO:0031594 GO:GO:0030900 GO:GO:0007219 GO:GO:0043065 Reactome:REACT_188257 GO:GO:0048286 GO:GO:0042987 GO:GO:0000122 GO:GO:0030426 GO:GO:0001756 GO:GO:0030326 GO:GO:0004175 GO:GO:0040011 GO:GO:0006816 GO:GO:0050435 GO:GO:0060048 GO:GO:0006509 GO:GO:0007220 Reactome:REACT_189085 GO:GO:0032091 GO:GO:0048538 GO:GO:0001921 GO:GO:0036064 GO:GO:0042640 GO:GO:0032436 GO:GO:0016485 GO:GO:1902043 GO:GO:1902042 GO:GO:0051444 GO:GO:0032469 GO:GO:0048854 GO:GO:0021904 GO:GO:0007175 GO:GO:0002286 GO:GO:0043589 GO:GO:0002244 GO:GO:2000059 GO:GO:0002573 GeneTree:ENSGT00390000016593 PANTHER:PTHR10202 GO:GO:0050820 eggNOG:NOG237920 HOGENOM:HOG000240228 HOVERGEN:HBG011375 OrthoDB:EOG7NGQBG MEROPS:A22.002 CTD:5664 KO:K04522 ChiTaRS:PSEN2 EMBL:U57324 EMBL:U57325 EMBL:AF038935 EMBL:AK014706 EMBL:BC010403 EMBL:U49111 RefSeq:NP_001122077.1 RefSeq:NP_035313.2 RefSeq:XP_006496775.1 UniGene:Mm.330850 ProteinModelPortal:Q61144 SMR:Q61144 BioGrid:202415 IntAct:Q61144 BindingDB:Q61144 PhosphoSite:Q61144 PaxDb:Q61144 PRIDE:Q61144 Ensembl:ENSMUST00000111104 GeneID:19165 KEGG:mmu:19165 UCSC:uc007dwe.1 InParanoid:Q61144 NextBio:295826 PRO:PR:Q61144 ArrayExpress:Q61144 Bgee:Q61144 CleanEx:MM_PSEN2 Genevestigator:Q61144 Uniprot:Q61144) HSP 1 Score: 398.667 bits (1023), Expect = 4.448e-134 Identity = 230/403 (57.07%), Postives = 282/403 (69.98%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+ E EE DP R EEE + +GAK VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E PL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACF+AILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 TQESEEDCEEDPDRYACSGAPGRPSGLEEELTLKYGAKRVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPLPGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:Psen2 "Presenilin-2" species:10116 "Rattus norvegicus" [GO:0000139 "Golgi membrane" evidence=IEA] [GO:0000776 "kinetochore" evidence=IEA] [GO:0001708 "cell fate specification" evidence=IEA] [GO:0001756 "somitogenesis" evidence=IEA] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IEA] [GO:0002244 "hematopoietic progenitor cell differentiation" evidence=IEA] [GO:0002286 "T cell activation involved in immune response" evidence=IEA] [GO:0002573 "myeloid leukocyte differentiation" evidence=IEA] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005637 "nuclear inner membrane" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0005813 "centrosome" evidence=IEA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA] [GO:0006816 "calcium ion transport" evidence=IEA] [GO:0007176 "regulation of epidermal growth factor-activated receptor activity" evidence=IEA] [GO:0007219 "Notch signaling pathway" evidence=IEA] [GO:0007613 "memory" evidence=IEA] [GO:0015031 "protein transport" evidence=IEA] [GO:0021904 "dorsal/ventral neural tube patterning" evidence=IEA] [GO:0030018 "Z disc" evidence=IEA] [GO:0030326 "embryonic limb morphogenesis" evidence=IEA] [GO:0030900 "forebrain development" evidence=IEA] [GO:0031333 "negative regulation of protein complex assembly" evidence=IEA] [GO:0032091 "negative regulation of protein binding" evidence=IEA] [GO:0032469 "endoplasmic reticulum calcium ion homeostasis" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0040011 "locomotion" evidence=IEA] [GO:0042640 "anagen" evidence=IEA] [GO:0043025 "neuronal cell body" evidence=IEA] [GO:0043065 "positive regulation of apoptotic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] [GO:0044267 "cellular protein metabolic process" evidence=IEA] [GO:0048167 "regulation of synaptic plasticity" evidence=IEA] [GO:0048286 "lung alveolus development" evidence=IEA] [GO:0048538 "thymus development" evidence=IEA] [GO:0048854 "brain morphogenesis" evidence=IEA] [GO:0050435 "beta-amyloid metabolic process" evidence=IEA] [GO:0050820 "positive regulation of coagulation" evidence=IEA] [GO:0050852 "T cell receptor signaling pathway" evidence=IEA] [GO:0060048 "cardiac muscle contraction" evidence=IEA] [GO:1902042 "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] [GO:1902043 "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA] InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 RGD:621060 GO:GO:0005829 GO:GO:0001708 GO:GO:0043085 GO:GO:0048167 GO:GO:0000139 GO:GO:0005887 GO:GO:0030018 GO:GO:0044267 GO:GO:0000776 GO:GO:0005813 GO:GO:0050852 GO:GO:0005789 GO:GO:0035556 GO:GO:0031333 GO:GO:0015031 GO:GO:0043025 GO:GO:0007613 GO:GO:0004190 GO:GO:0001666 GO:GO:0030900 GO:GO:0007176 GO:GO:0007219 GO:GO:0043065 GO:GO:0048286 GO:GO:0001756 GO:GO:0030326 GO:GO:0040011 GO:GO:0006816 GO:GO:0050435 GO:GO:0060048 GO:GO:0006509 GO:GO:0032091 GO:GO:0048538 GO:GO:0042640 GO:GO:0016485 GO:GO:1902043 GO:GO:1902042 GO:GO:0001933 GO:GO:0005637 GO:GO:0032469 GO:GO:0048854 GO:GO:0021904 GO:GO:0002286 GO:GO:0002244 GO:GO:0002573 GeneTree:ENSGT00390000016593 PANTHER:PTHR10202 GO:GO:0050820 eggNOG:NOG237920 HOGENOM:HOG000240228 HOVERGEN:HBG011375 TreeFam:TF315040 OrthoDB:EOG7NGQBG MEROPS:A22.002 CTD:5664 KO:K04522 OMA:RSCQEGR EMBL:X99267 EMBL:D83700 EMBL:AB004454 EMBL:BC078805 RefSeq:NP_112349.2 RefSeq:XP_006250467.1 RefSeq:XP_006250468.1 RefSeq:XP_006250469.1 RefSeq:XP_006250470.1 RefSeq:XP_006250471.1 UniGene:Rn.11045 PhosphoSite:O88777 PaxDb:O88777 PRIDE:O88777 Ensembl:ENSRNOT00000040203 GeneID:81751 KEGG:rno:81751 NextBio:615506 Genevestigator:O88777 Uniprot:O88777) HSP 1 Score: 389.808 bits (1000), Expect = 1.323e-130 Identity = 227/403 (56.33%), Postives = 282/403 (69.98%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S E E+ DP + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEV KTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E P Q EEEE+RG+KLGLGDFIFYS+LVGKA++ GDW+TTLACF+AILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 SQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAP-QPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. GO
Match: - (symbol:Psen2 "presenilin 2" species:10116 "Rattus norvegicus" [GO:0000122 "negative regulation of transcription from RNA polymerase II promoter" evidence=ISO] [GO:0000139 "Golgi membrane" evidence=IEA] [GO:0000776 "kinetochore" evidence=IEA;ISO] [GO:0001666 "response to hypoxia" evidence=IEP] [GO:0001708 "cell fate specification" evidence=IEA;ISO] [GO:0001756 "somitogenesis" evidence=IEA;ISO] [GO:0001921 "positive regulation of receptor recycling" evidence=ISO] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IEA;ISO] [GO:0001942 "hair follicle development" evidence=ISO] [GO:0002244 "hematopoietic progenitor cell differentiation" evidence=IEA;ISO] [GO:0002286 "T cell activation involved in immune response" evidence=IEA;ISO] [GO:0002573 "myeloid leukocyte differentiation" evidence=IEA;ISO] [GO:0003674 "molecular_function" evidence=ND] [GO:0004175 "endopeptidase activity" evidence=ISO] [GO:0004190 "aspartic-type endopeptidase activity" evidence=IEA] [GO:0005575 "cellular_component" evidence=ND] [GO:0005637 "nuclear inner membrane" evidence=IEA;ISO] [GO:0005783 "endoplasmic reticulum" evidence=ISO] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=ISO] [GO:0005813 "centrosome" evidence=IEA;ISO] [GO:0005829 "cytosol" evidence=IEA;ISO] [GO:0005887 "integral component of plasma membrane" evidence=IEA;ISO] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA;ISO] [GO:0006816 "calcium ion transport" evidence=IEA;ISO] [GO:0007175 "negative regulation of epidermal growth factor-activated receptor activity" evidence=ISO] [GO:0007176 "regulation of epidermal growth factor-activated receptor activity" evidence=IEA;ISO] [GO:0007219 "Notch signaling pathway" evidence=IEA;ISO] [GO:0007611 "learning or memory" evidence=ISO] [GO:0007613 "memory" evidence=IEA;ISO] [GO:0009790 "embryo development" evidence=ISO] [GO:0015031 "protein transport" evidence=IEA;ISO] [GO:0016020 "membrane" evidence=ISO] [GO:0016485 "protein processing" evidence=ISO] [GO:0021904 "dorsal/ventral neural tube patterning" evidence=IEA;ISO] [GO:0030018 "Z disc" evidence=IEA;ISO] [GO:0030326 "embryonic limb morphogenesis" evidence=IEA;ISO] [GO:0030900 "forebrain development" evidence=IEA;ISO] [GO:0031333 "negative regulation of protein complex assembly" evidence=IEA;ISO] [GO:0032091 "negative regulation of protein binding" evidence=IEA;ISO] [GO:0032436 "positive regulation of proteasomal ubiquitin-dependent protein catabolic process" evidence=ISO] [GO:0032469 "endoplasmic reticulum calcium ion homeostasis" evidence=IEA;ISO] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0036064 "ciliary basal body" evidence=ISO] [GO:0040011 "locomotion" evidence=IEA;ISO] [GO:0042640 "anagen" evidence=IEA;ISO] [GO:0043025 "neuronal cell body" evidence=IEA;ISO] [GO:0043065 "positive regulation of apoptotic process" evidence=IEA;ISO] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA;ISO] [GO:0043234 "protein complex" evidence=ISO] [GO:0043393 "regulation of protein binding" evidence=ISO] [GO:0043589 "skin morphogenesis" evidence=ISO] [GO:0044267 "cellular protein metabolic process" evidence=IEA;ISO] [GO:0048167 "regulation of synaptic plasticity" evidence=IEA;ISO] [GO:0048286 "lung alveolus development" evidence=IEA;ISO] [GO:0048538 "thymus development" evidence=IEA;ISO] [GO:0048854 "brain morphogenesis" evidence=IEA;ISO] [GO:0050435 "beta-amyloid metabolic process" evidence=IEA;ISO] [GO:0050820 "positive regulation of coagulation" evidence=IEA;ISO] [GO:0050852 "T cell receptor signaling pathway" evidence=IEA;ISO] [GO:0051444 "negative regulation of ubiquitin-protein ligase activity" evidence=ISO] [GO:0051604 "protein maturation" evidence=ISO] [GO:0060048 "cardiac muscle contraction" evidence=IEA;ISO] [GO:1902042 "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA;ISO] [GO:1902043 "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" evidence=IEA;ISO] [GO:2000059 "negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process" evidence=ISO] [GO:2001234 "negative regulation of apoptotic signaling pathway" evidence=ISO] InterPro:IPR001108 InterPro:IPR001493 InterPro:IPR006639 Pfam:PF01080 PRINTS:PR01072 PRINTS:PR01074 SMART:SM00730 RGD:621060 GO:GO:0005829 GO:GO:0001708 GO:GO:0043085 GO:GO:0048167 GO:GO:0000139 GO:GO:0005887 GO:GO:0030018 GO:GO:0044267 GO:GO:0000776 GO:GO:0005813 GO:GO:0050852 GO:GO:0005789 GO:GO:0035556 GO:GO:0031333 GO:GO:0015031 GO:GO:0043025 GO:GO:0007613 GO:GO:0004190 GO:GO:0001666 GO:GO:0030900 GO:GO:0007176 GO:GO:0007219 GO:GO:0043065 GO:GO:0048286 GO:GO:0001756 GO:GO:0030326 GO:GO:0040011 GO:GO:0006816 GO:GO:0050435 GO:GO:0060048 GO:GO:0006509 GO:GO:0032091 GO:GO:0048538 GO:GO:0042640 GO:GO:0016485 GO:GO:1902043 GO:GO:1902042 GO:GO:0001933 GO:GO:0005637 GO:GO:0032469 GO:GO:0048854 GO:GO:0021904 GO:GO:0002286 GO:GO:0002244 GO:GO:0002573 GeneTree:ENSGT00390000016593 PANTHER:PTHR10202 GO:GO:0050820 eggNOG:NOG237920 HOGENOM:HOG000240228 HOVERGEN:HBG011375 TreeFam:TF315040 OrthoDB:EOG7NGQBG MEROPS:A22.002 CTD:5664 KO:K04522 OMA:RSCQEGR EMBL:X99267 EMBL:D83700 EMBL:AB004454 EMBL:BC078805 RefSeq:NP_112349.2 RefSeq:XP_006250467.1 RefSeq:XP_006250468.1 RefSeq:XP_006250469.1 RefSeq:XP_006250470.1 RefSeq:XP_006250471.1 UniGene:Rn.11045 PhosphoSite:O88777 PaxDb:O88777 PRIDE:O88777 Ensembl:ENSRNOT00000040203 GeneID:81751 KEGG:rno:81751 NextBio:615506 Genevestigator:O88777 Uniprot:O88777) HSP 1 Score: 389.808 bits (1000), Expect = 1.323e-130 Identity = 227/403 (56.33%), Postives = 282/403 (69.98%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S E E+ DP + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEV KTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E P Q EEEE+RG+KLGLGDFIFYS+LVGKA++ GDW+TTLACF+AILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 SQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAP-QPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940342|gb|GAXK01018211.1| (TSA: Calanus finmarchicus comp33636_c1_seq2 transcribed RNA sequence) HSP 1 Score: 442.58 bits (1137), Expect = 7.356e-151 Identity = 261/404 (64.60%), Postives = 311/404 (76.98%), Query Frame = 0
Query: 29 NHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWXXXXXXXXXXXXXXXXXGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYXXXXXXXXXXXXXKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSD----PKRPNR---------------------------------------RRDNQRMAAXXXXXXXXXXXXXXXXXXXXXXXXXDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+GA +VI LF+PVT+CMA VV TI S+T YTE+ G YLVYTPFHE +++ GT+AW A ANAGI+L VIAVMT +L+++YKY+C+ LIHGWLF+SS MLLFLFSY++L EVLK YNLPMDYITLA ++WNFG+VGM+SI+WKAPLLLQQ+YLIFISAL+AL FIKYLP++TTWAVLA ISLW LFAVLAPFGPLRILVETAQERNE IFPSLIYS+G++Y+++GMAD+ + P+R R R QR A + + P + VEEEEED+G+KLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTL+FLA+FR+ALPALPISITFGLIFYFLTKEI+TPF D +SS+QI+I
Sbjct: 17 KYGAHHVIKLFSPVTMCMAVVVATISSITYYTEK-GTYLVYTPFHEETEDVGTLAWQALANAGIMLGVIAVMTGLLVLAYKYRCTKLIHGWLFMSSLMLLFLFSYLYLAEVLKAYNLPMDYITLAIVIWNFGMVGMISIYWKAPLLLQQAYLIFISALMALIFIKYLPDWTTWAVLAVISLWDLFAVLAPFGPLRILVETAQERNEQIFPSLIYSSGMVYALVGMADTEGEAPVAPRRQGRTGSAGAEERAEGEVSAQTRPQGGEDARDGFSDTWVRENDERSRQRSA---RVSQTGAGPRSGVRTELVEEEEEDKGVKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLVFLALFRRALPALPISITFGLIFYFLTKEIVTPFCDALSSQQIFI 1216
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940343|gb|GAXK01018210.1| (TSA: Calanus finmarchicus comp33636_c1_seq1 transcribed RNA sequence) HSP 1 Score: 443.736 bits (1140), Expect = 7.438e-151 Identity = 261/404 (64.60%), Postives = 311/404 (76.98%), Query Frame = 0
Query: 29 NHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWXXXXXXXXXXXXXXXXXGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYXXXXXXXXXXXXXKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSD----PKRPNR---------------------------------------RRDNQRMAAXXXXXXXXXXXXXXXXXXXXXXXXXDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+GA +VI LF+PVT+CMA VV TI S+T YTE+ G YLVYTPFHE +++ GT+AW A ANAGI+L VIAVMT +L+++YKY+C+ LIHGWLF+SS MLLFLFSY++L EVLK YNLPMDYITLA ++WNFG+VGM+SI+WKAPLLLQQ+YLIFISAL+AL FIKYLP++TTWAVLA ISLW LFAVLAPFGPLRILVETAQERNE IFPSLIYS+G++Y+++GMAD+ + P+R R R QR A + + P + VEEEEED+G+KLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTL+FLA+FR+ALPALPISITFGLIFYFLTKEI+TPF D +SS+QI+I
Sbjct: 122 KYGAHHVIKLFSPVTMCMAVVVATISSITYYTEK-GTYLVYTPFHEETEDVGTLAWQALANAGIMLGVIAVMTGLLVLAYKYRCTKLIHGWLFMSSLMLLFLFSYLYLAEVLKAYNLPMDYITLAIVIWNFGMVGMISIYWKAPLLLQQAYLIFISALMALIFIKYLPDWTTWAVLAVISLWDLFAVLAPFGPLRILVETAQERNEQIFPSLIYSSGMVYALVGMADTEGEAPVAPRRQGRTGSAGAEERAEGEVSAQTRPQGGEDARDGFSDTWVRENDERSRQRSA---RVSQTGAGPRSGVRTELVEEEEEDKGVKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLVFLALFRRALPALPISITFGLIFYFLTKEIVTPFCDALSSQQIFI 1321
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940341|gb|GAXK01018212.1| (TSA: Calanus finmarchicus comp33636_c1_seq3 transcribed RNA sequence) HSP 1 Score: 388.652 bits (997), Expect = 1.911e-130 Identity = 233/361 (64.54%), Postives = 277/361 (76.73%), Query Frame = 0
Query: 72 FHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWXXXXXXXXXXXXXXXXXGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYXXXXXXXXXXXXXKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSD----PKRPNR---------------------------------------RRDNQRMAAXXXXXXXXXXXXXXXXXXXXXXXXXDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
FHE +++ GT+AW A ANAGI+L VIAVMT +L+++YKY+C+ LIHGWLF+SS MLLFLFSY++L EVLK YNLPMDYITLA ++WNFG+VGM+SI+WKAPLLLQQ+YLIFISAL+AL FIKYLP++TTWAVLA ISLW LFAVLAPFGPLRILVETAQERNE IFPSLIYS+G++Y+++GMAD+ + P+R R R QR A + + P + VEEEEED+G+KLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTL+FLA+FR+ALPALPISITFGLIFYFLTKEI+TPF D +SS+QI+I
Sbjct: 2 FHEETEDVGTLAWQALANAGIMLGVIAVMTGLLVLAYKYRCTKLIHGWLFMSSLMLLFLFSYLYLAEVLKAYNLPMDYITLAIVIWNFGMVGMISIYWKAPLLLQQAYLIFISALMALIFIKYLPDWTTWAVLAVISLWDLFAVLAPFGPLRILVETAQERNEQIFPSLIYSSGMVYALVGMADTEGEAPVAPRRQGRTGSAGAEERAEGEVSAQTRPQGGEDARDGFSDTWVRENDERSRQRSA---RVSQTGAGPRSGVRTELVEEEEEDKGVKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLVFLALFRRALPALPISITFGLIFYFLTKEIVTPFCDALSSQQIFI 1075
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940338|gb|GAXK01018215.1| (TSA: Calanus finmarchicus comp33636_c5_seq2 transcribed RNA sequence) HSP 1 Score: 253.832 bits (647), Expect = 5.272e-81 Identity = 149/200 (74.50%), Postives = 177/200 (88.50%), Query Frame = 0
Query: 29 NHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWXXXXXXXXXXXXXXXXXGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYXXXXXXXXXXXXXKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVET 228
+GA +VI LF+PVT+CMA VV TI S+T YTE+ G YLVYTPFHE +++ GT+AW A ANAGI+L VIAVMT +L+++YKY+C+ LIHGWLF+SS MLLFLFSY++L EVLK YNLPMDYITLA ++WNFG+VGM+SI+WKAPLLLQQSYLIFISAL+AL FIKYLP++TTWAVLA ISLW LFAVLAPFGPLRILVET
Sbjct: 1 KYGAHHVIKLFSPVTMCMAVVVATISSITYYTEK-GTYLVYTPFHEETEDVGTLAWQALANAGIMLGVIAVMTGLLVLAYKYRCTKLIHGWLFMSSLMLLFLFSYLYLAEVLKAYNLPMDYITLAIVIWNFGMVGMISIYWKAPLLLQQSYLIFISALMALIFIKYLPDWTTWAVLAVISLWDLFAVLAPFGPLRILVET 597
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940337|gb|GAXK01018216.1| (TSA: Calanus finmarchicus comp33636_c5_seq3 transcribed RNA sequence) HSP 1 Score: 246.514 bits (628), Expect = 2.886e-78 Identity = 145/196 (73.98%), Postives = 173/196 (88.27%), Query Frame = 0
Query: 29 NHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWXXXXXXXXXXXXXXXXXGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYXXXXXXXXXXXXXKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRI 224
+GA +VI LF+PVT+CMA VV TI S+T YTE+ G YLVYTPFHE +++ GT+AW A ANAGI+L VIAVMT +L+++YKY+C+ LIHGWLF+SS MLLFLFSY++L EVLK YNLPMDYITLA ++WNFG+VGM+SI+WKAPLLLQQSYLIFISAL+AL FIKYLP++TTWAVLA ISLW LFAVLAPFGPLRI
Sbjct: 1 KYGAHHVIKLFSPVTMCMAVVVATISSITYYTEK-GTYLVYTPFHEETEDVGTLAWQALANAGIMLGVIAVMTGLLVLAYKYRCTKLIHGWLFMSSLMLLFLFSYLYLAEVLKAYNLPMDYITLAIVIWNFGMVGMISIYWKAPLLLQQSYLIFISALMALIFIKYLPDWTTWAVLAVISLWDLFAVLAPFGPLRI 585
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940339|gb|GAXK01018214.1| (TSA: Calanus finmarchicus comp33636_c5_seq1 transcribed RNA sequence) HSP 1 Score: 197.978 bits (502), Expect = 1.241e-58 Identity = 112/203 (55.17%), Postives = 135/203 (66.50%), Query Frame = 0
Query: 227 ETAQERNEPIFPSLIYSAGIMYSVIGMADSSSD----PKRPN------------------------------------RRRDNQRMAAXXXXXXXXXXXXXXXXXXXXXXXXXDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
ETAQERNE IFPSLIYS+G++Y+++GMAD+ + P+R R D + ++ + P + VEEEEED+G+KLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTL+FLA+FR+ALPALPISITFGLIFYFLTKEI+TPF D +SS+QI+I
Sbjct: 313 ETAQERNEQIFPSLIYSSGMVYALVGMADTEGEAPVAPRRQGRTGSAGAEERAEGEVSAQTRPQGGEDARDGFSDTWVRENDERSRQRSARVSQTGAGPRSGVRTELVEEEEEDKGVKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLVFLALFRRALPALPISITFGLIFYFLTKEIVTPFCDALSSQQIFI 921
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940340|gb|GAXK01018213.1| (TSA: Calanus finmarchicus comp33636_c1_seq4 transcribed RNA sequence) HSP 1 Score: 170.629 bits (431), Expect = 1.099e-48 Identity = 79/90 (87.78%), Postives = 88/90 (97.78%), Query Frame = 0
Query: 300 DRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
D+G+KLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTL+FLA+FR+ALPALPISITFGLIFYFLTKEI+TPF D +SS+QI+I
Sbjct: 227 DKGVKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLVFLALFRRALPALPISITFGLIFYFLTKEIVTPFCDALSSQQIFI 496
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940336|gb|GAXK01018217.1| (TSA: Calanus finmarchicus comp33636_c5_seq4 transcribed RNA sequence) HSP 1 Score: 150.599 bits (379), Expect = 4.042e-42 Identity = 72/81 (88.89%), Postives = 79/81 (97.53%), Query Frame = 0
Query: 309 DFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
DFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTL+FLA+FR+ALPALPISITFGLIFYFLTKEI+TPF D +SS+QI+I
Sbjct: 313 DFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLVFLALFRRALPALPISITFGLIFYFLTKEIVTPFCDALSSQQIFI 555
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592940335|gb|GAXK01018218.1| (TSA: Calanus finmarchicus comp33636_c5_seq5 transcribed RNA sequence) HSP 1 Score: 127.872 bits (320), Expect = 2.957e-34 Identity = 58/91 (63.74%), Postives = 75/91 (82.42%), Query Frame = 0
Query: 29 NHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGW 119
+GA +VI LF+PVT+CMA VV TI S+T YTE+ G YLVYTPFHE +++ GT+AW A ANAGI+L VIAVMT +L+++YKY+C+ LIHGW
Sbjct: 18 KYGAHHVIKLFSPVTMCMAVVVATISSITYYTEK-GTYLVYTPFHEETEDVGTLAWQALANAGIMLGVIAVMTGLLVLAYKYRCTKLIHGW 287
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Match: gi|592840001|gb|GAXK01117543.1| (TSA: Calanus finmarchicus comp607688_c1_seq2 transcribed RNA sequence) HSP 1 Score: 40.0466 bits (92), Expect = 3.485e-3 Identity = 18/34 (52.94%), Postives = 26/34 (76.47%), Query Frame = 0
Query: 82 IAWNAFANAGILLAVIAVMTVILIISYKYKCSWL 115
IA A ANAGI+L VIAVM +++++YK +C+ L
Sbjct: 86 IALQALANAGIVLGVIAVMMGLVVLAYKCRCTKL 187
BLAST of EMLSAG00000000448 vs. L. salmonis peptides
Match: EMLSAP00000000448 (pep:novel supercontig:LSalAtl2s:LSalAtl2s106:189612:190849:-1 gene:EMLSAG00000000448 transcript:EMLSAT00000000448 description:"maker-LSalAtl2s106-augustus-gene-2.11") HSP 1 Score: 778.474 bits (2009), Expect = 0.000e+0 Identity = 389/389 (100.00%), Postives = 389/389 (100.00%), Query Frame = 0
Query: 1 MSSEGEEVRIRDPRRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
MSSEGEEVRIRDPRRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI
Sbjct: 1 MSSEGEEVRIRDPRRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|37082570|sp|Q90ZE4.2|PSN2_DANRE (RecName: Full=Presenilin-2; Short=PS-2; Short=Zf-PS2; AltName: Full=Pre2) HSP 1 Score: 425.631 bits (1093), Expect = 1.344e-146 Identity = 223/380 (58.68%), Postives = 283/380 (74.47%), Query Frame = 0
Query: 12 DPRRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEE-EEDRGIKLGLGDFIFYSILVGKASSY-GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
D R + + EEEE + +GAK+VIMLF PVTLCM VV TI SV+ YTE+ G L+YTPF E ++ G N+ N ++++VI MT+IL++ YKY+C IHGWL LSS MLLF FS+++LGEV KTYN+ MDY TL I+WNFGVVGM+ IHWK PL LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ +++ ++GMADS++ RRR + + + P ++Q EE+ EEDRG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPISITFGL+FYF T ++ PFMD +++ Q YI
Sbjct: 63 DRERADTPDGEEEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTEKSGQRLIYTPFEEDPNSVGQRLLNSVLNTLVMISVIVFMTIILVLLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFKTYNVAMDYPTLLMIIWNFGVVGMICIHWKGPLRLQQAYLIVISALMALIFIKYLPEWSAWVILGAISIYDLIAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW-MVGMADSNNPDSAGERRRSGGGVRTQEGVESEHDAPQAGRRQYSAEEDLEEDRGVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTDNLVRPFMDSLAAHQYYI 441
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|6093851|sp|O12977.1|PSN2_XENLA (RecName: Full=Presenilin-2; Short=PS-2; AltName: Full=Presenilin beta; Short=PS-beta) HSP 1 Score: 419.083 bits (1076), Expect = 7.949e-144 Identity = 219/367 (59.67%), Postives = 277/367 (75.48%), Query Frame = 0
Query: 29 NHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRR----RDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGK--ASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+GA++VIMLF PVTLCM VV TI SV+ YTE+DG L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL LSS MLLF+F+YI+L EV KTYN+ MDY TL ++WNFG VGM+ IHWK PL LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ +M++V GMADS++ R N++ N A S ++ + +Q Q E+ +E+RG+KLGLGDFIFYS+LVGK A++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T I+ PFMD ++S Q+YI
Sbjct: 85 KYGARHVIMLFVPVTLCMVVVVATIKSVSFYTEKDGQ-LIYTPFSEDTTSVGERLLNSVLNTLIMISVILVMTIFLVLLYKYRCYKFIHGWLILSSLMLLFMFTYIYLSEVFKTYNIAMDYPTLFMVIWNFGAVGMICIHWKGPLQLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLLAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMMWTV-GMADSATADGRMNQQVQHIDRNTPEGANSTVEDAAETRIQTQSNLSSEDPDEERGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNIVRPFMDTLASHQMYI 449
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|1709858|sp|P49810.1|PSN2_HUMAN (RecName: Full=Presenilin-2; Short=PS-2; AltName: Full=AD3LP; AltName: Full=AD5; AltName: Full=E5-1; AltName: Full=STM-2; Contains: RecName: Full=Presenilin-2 NTF subunit; Contains: RecName: Full=Presenilin-2 CTF subunit) HSP 1 Score: 406.371 bits (1043), Expect = 7.540e-139 Identity = 233/403 (57.82%), Postives = 286/403 (70.97%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S E EE DP R + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E+ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 SQENEEDGEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|122143204|sp|Q0MS45.1|PSN2_PIG (RecName: Full=Presenilin-2; Short=PS-2; Contains: RecName: Full=Presenilin-2 NTF subunit; Contains: RecName: Full=Presenilin-2 CTF subunit) HSP 1 Score: 404.06 bits (1037), Expect = 5.016e-138 Identity = 232/403 (57.57%), Postives = 285/403 (70.72%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S + EE DP R + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E+ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 SQDSEEDHEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLITSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|75042205|sp|Q5RCN9.1|PSN2_PONAB (RecName: Full=Presenilin-2; Short=PS-2; Contains: RecName: Full=Presenilin-2 NTF subunit; Contains: RecName: Full=Presenilin-2 CTF subunit) HSP 1 Score: 404.06 bits (1037), Expect = 5.473e-138 Identity = 232/403 (57.57%), Postives = 285/403 (70.72%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S E EE DP R + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI MT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E+ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 SQENEEDGEEDPDRYICSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|115502442|sp|Q9XT96.2|PSN2_BOVIN (RecName: Full=Presenilin-2; Short=PS-2; Contains: RecName: Full=Presenilin-2 NTF subunit; Contains: RecName: Full=Presenilin-2 CTF subunit) HSP 1 Score: 399.823 bits (1026), Expect = 2.369e-136 Identity = 224/376 (59.57%), Postives = 277/376 (73.67%), Query Frame = 0
Query: 23 EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI MT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E ++ PPL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 77 EEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFSEDTPSVGQRLLNSVLNTLIMISVIVTMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPDVFEPPLPGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 449
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|37154738|sp|Q61144.3|PSN2_MOUSE (RecName: Full=Presenilin-2; Short=PS-2; Contains: RecName: Full=Presenilin-2 NTF subunit; Contains: RecName: Full=Presenilin-2 CTF subunit) HSP 1 Score: 398.667 bits (1023), Expect = 6.663e-136 Identity = 230/403 (57.07%), Postives = 282/403 (69.98%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+ E EE DP R EEE + +GAK VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E PL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACF+AILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 TQESEEDCEEDPDRYACSGAPGRPSGLEEELTLKYGAKRVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPLPGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|6174932|sp|O88777.2|PSN2_RAT (RecName: Full=Presenilin-2; Short=PS-2; Contains: RecName: Full=Presenilin-2 NTF subunit; Contains: RecName: Full=Presenilin-2 CTF subunit) HSP 1 Score: 389.808 bits (1000), Expect = 2.053e-132 Identity = 227/403 (56.33%), Postives = 282/403 (69.98%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S E E+ DP + EEE + +GAK+VIMLF PVTLCM VV TI SV YTE++G L+YTPF E + + G N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEV KTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E P Q EEEE+RG+KLGLGDFIFYS+LVGKA++ GDW+TTLACF+AILIGLCLTL+ LA+F+KALPALPISITFGLIFYF T ++ PFMD ++S Q+YI
Sbjct: 49 SQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAP-QPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|6093850|sp|P79801.1|PSN2_MICMU (RecName: Full=Presenilin-2; Short=PS-2; Contains: RecName: Full=Presenilin-2 NTF subunit; Contains: RecName: Full=Presenilin-2 CTF subunit) HSP 1 Score: 387.497 bits (994), Expect = 1.588e-131 Identity = 224/398 (56.28%), Postives = 278/398 (69.85%), Query Frame = 0
Query: 4 EGEEVRIRDPRRREVQELE------EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA--DSSSD-----PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSY--GDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQ 386
+ EE DP R + EEE + +GAK+VIML PVTLCM VV TI SV YTE++G L+YTPF E + + N+ N I+++VI VMT+ L++ YKY+C IHGWL +SS MLLFLF+YI+LGEVLKTYN+ MDY TL +WNFG VGM+ IHWK PL+LQQ+YLI ISAL+AL FIKYLP ++ W +L IS++ L AVL P GPLR+LVETAQERNEPIFP+LIYS+ ++++V GMA D SS P P D+ E E+ PL EEEE+RG+KLGLGDFIFYS+LVGKA++ GDWNTTLACFVAILIGLCLTL+ LA+F+KALPALPISITFGL+FYF T ++ PFMD ++ Q
Sbjct: 51 DSEEDGEEDPDRYVSSGVPGRPPGPEEELTLKYGAKHVIMLSVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVSQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLVLTVWNFGAVGMVCIHWKGPLMLQQAYLIAISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTV-GMAKLDPSSQGALQLPYDPEMEEDSYDSLGEPSYPEVFEAPLPGYPG-EELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLVFYFSTDNLVRPFMDTLAYHQ 445
BLAST of EMLSAG00000000448 vs. SwissProt
Match: gi|21264494|sp|P52166.2|PSN_CAEEL (RecName: Full=Presenilin sel-12; AltName: Full=Suppressor/enhancer of lin-12 protein 12) HSP 1 Score: 384.415 bits (986), Expect = 2.117e-130 Identity = 208/413 (50.36%), Postives = 273/413 (66.10%), Query Frame = 0
Query: 15 RREVQELEE--EEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVI--------------------------GMADSSSD-PKRPNRRRDNQRMAAESQX-------------QELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSR 385
R QE E EE + +GA +VI LF PV+LCMA VV T+ ++T Y++ +G +L+YTPF +D+ + NA ++L V+ +MTV+LI+ YKYK LIHGWL +SSF+LLFLF+ I++ EVLK++++ + + F + N+GV+GMM IHWK PL LQQ YLI +SAL+AL FIKYLP +T W VL IS+W L AVL P GPLR LVETAQERNEPIFP+LIYS+G++Y + G A SS+ PKRP +R Q++ ES +EL+ Q EEE+RG+KLGLGDFIFYS+L+GKASSY DWNTT+AC+VAILIGLC TL+ LA+F++ALPALPISI GLIFYF T+ IITPF+ ++S +
Sbjct: 28 NRNSQEDENVVEEAELKYGASHVIHLFVPVSLCMALVVFTMNTITFYSQNNGRHLLYTPFVRETDSIVEKGLMSLGNALVMLCVVVLMTVLLIVFYKYKFYKLIHGWLIVSSFLLLFLFTTIYVQEVLKSFDVSPSALLVLFGLGNYGVLGMMCIHWKGPLRLQQFYLITMSALMALVFIKYLPEWTVWFVLFVISVWDLVAVLTPKGPLRYLVETAQERNEPIFPALIYSSGVIYPYVLVTAVENTTDPREPTSSDSNTSTAFPGEASCSSETPKRPKVKRIPQKVQIESNTTASTTQNSGVRVERELAAERPTVQDANFHRHEEEERGVKLGLGDFIFYSVLLGKASSYFDWNTTIACYVAILIGLCFTLVLLAVFKRALPALPISIFSGLIFYFCTRWIITPFVTQVSQK 440
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: gb|EFA07178.2| (Presenilin homolog-like Protein [Tribolium castaneum]) HSP 1 Score: 439.884 bits (1130), Expect = 3.414e-152 Identity = 237/395 (60.00%), Postives = 291/395 (73.67%), Query Frame = 0
Query: 13 PRRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSD--PKRPNRRR----------------DNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
P EV EL +EE + +GAK+VI LF PV+LCM VV TI +V Y+ +D YLVYTPFHE S + T WNA AN+ IL+AVI VMTV+LI+ YKY+C IHGWL LSS MLL +FSY++L E+L+ YN+PMDY T+ +MWNFGV+GM+ IHW+ PL+LQQ+YLIF++AL+AL FIKYLP +TTWAVLA IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ MY+ MA S+D P R R DN + E+ P + + + +EEE+RG+KLGLGDFIFYS+LVGKASSYGDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPISITFGLIFYF TKEI++PF D +++ Q++I
Sbjct: 71 PVDYEVAELRDEEEELKYGAKHVIKLFAPVSLCMVVVVATISAVNFYSVKD-MYLVYTPFHEESSDTSTKVWNAAANSLILMAVIVVMTVLLIVLYKYRCYKTIHGWLILSSLMLLTVFSYLYLEEILRAYNIPMDYPTIVLLMWNFGVMGMVCIHWQGPLVLQQAYLIFVAALMALVFIKYLPEWTTWAVLAVISVWDLVAVLMPKGPLRILVETAQERNEQIFPALIYSSTYMYAYTSMATPSNDENPPRGAAARSSADSTEEHGFTQDWVDNHSSRVAQRRLEVHDVP-RGAPRTQIHQEEEERGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATKEIVSPFADSLANEQVFI 463
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: EEB13397.1 (conserved hypothetical protein [Pediculus humanus corporis]) HSP 1 Score: 427.172 bits (1097), Expect = 5.414e-147 Identity = 240/398 (60.30%), Postives = 284/398 (71.36%), Query Frame = 0
Query: 23 EEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGM-ADSSSDP----KRPNRRRD------------------NQRMAAESQXQELSPPPLQQQQQP--------PVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+EE + +GAK+VI LF PV+LCM VV TI S+ YT D Y VYTPFHE NPGT AWNA AN+ IL+AVI VMT++LII YK +C IHGWL SS MLLFLFSY++L EVL+ YN+PMDY TL IMWNFGVVGM+ IHWK PLLLQQ+YLIFI+AL+AL FIKYLP +T W VLA IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ MY+ + M ++ + +P K N R+ +R E Q E+ P Q + V EEE+RG+KLGLGDFIFYS+LVGKASSYGDWNTT+ACFVAILIGLCLTL+ LA+FRKALPALPISITFGLIFYF TK+I+ PF D ++ QI+I
Sbjct: 81 QEELELKYGAKHVIKLFAPVSLCMLVVVATISSIKFYTTSDM-YFVYTPFHETDSNPGTKAWNAVANSLILIAVIVVMTIVLIILYKKRCYKTIHGWLIASSLMLLFLFSYLYLEEVLRAYNIPMDYFTLTIIMWNFGVVGMICIHWKGPLLLQQAYLIFIAALMALVFIKYLPEWTAWVVLAVISIWDLIAVLTPRGPLRILVETAQERNEQIFPALIYSSTFMYNYVNMTSEETKNPTSSLKESNSTRNFEEDPESGFVRGWMNPQRAKRRNEEIQQSEVRFHPQQSEGHSNPGPVGTNAVTVEEEERGVKLGLGDFIFYSVLVGKASSYGDWNTTVACFVAILIGLCLTLLLLAVFRKALPALPISITFGLIFYFTTKKIVKPFADNLAGEQIFI 477
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: EFX90351.1 (putative protease presenilin [Daphnia pulex]) HSP 1 Score: 422.165 bits (1084), Expect = 2.098e-145 Identity = 233/388 (60.05%), Postives = 288/388 (74.23%), Query Frame = 0
Query: 29 NHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMAD-------------SSSDPKRPN--------RRRDNQRMAAES---QXQELSPPPLQQQQQP---PVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+GA +VI LF PV+LCM VV TI SVT YT++ G YLVYTPFHE S + GT WNA ANA ILL VI VMTV LI+ YKY+C +IHGWL +SS MLLF+F+Y++LGEVL+TYN+P+DYI+L FIMWNFGVVGM++IHWKAPL LQQ+YLIF++AL+AL FIKYLP +TTW VL IS+W L AVL+P GPLRILVETAQ RNEP+FP+LIYS+ + Y + D +++ P+ P + QR A Q P Q QP ++++EE+RGIKLGLGDFIFYS+LVGKASSYGDWNTT+ACFVAILIGLCLTL+ LAIFRKALPALPISITFGL+FYF T +++ PF D ++++Q++I
Sbjct: 62 KYGAAHVIKLFVPVSLCMMVVVATISSVTYYTQK-GIYLVYTPFHEDSPDTGTKVWNAVANAAILLGVIVVMTVFLIMLYKYRCYKIIHGWLIMSSLMLLFIFAYLYLGEVLRTYNIPLDYISLLFIMWNFGVVGMIAIHWKAPLHLQQAYLIFVAALMALVFIKYLPEWTTWVVLGVISIWDLVAVLSPRGPLRILVETAQSRNEPLFPALIYSSTVAYMAVMATDQSSTSNSTSNNETAANGPRSPTDGGFTPAWNQEAEQRTEARRHRVQAAAAEAPRAAPQPQPVTEEIDDDEEERGIKLGLGDFIFYSVLVGKASSYGDWNTTIACFVAILIGLCLTLLLLAIFRKALPALPISITFGLVFYFATSKLVAPFADSLTAQQVFI 448
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: gb|EEC13172.1| (presenilin, putative, partial [Ixodes scapularis]) HSP 1 Score: 419.468 bits (1077), Expect = 1.472e-144 Identity = 230/424 (54.25%), Postives = 292/424 (68.87%), Query Frame = 0
Query: 2 SSEGEEVRIRDPRRREVQELEEE-----EFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMAD------------SSSDPKRPNRRRDNQRM---------------AAESQXQELSPPPLQQQQQPPVEE----EEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
S EG EV ++ + E E + +GAK+VI LF PV+LCM VV TI S++ Y + YLVYTPF + + + GT W +FANA IL+ VI VMT++LI+ YK++C +IH WL +SS +L+FLF+YI+LGEVL+ YN+PMDY+T+A +MWNFGVVGM+SIHWK PLLLQQ+YLI +SAL+AL FIKYLP++T W VL IS+W L AVL P GPLRILVETAQERNEPIFP+LIYS+ ++++V+ MAD S SD RR + + L+ Q P V++ EEE+RG+KLGLGDFIFYS+LVGKASSYGDWNTT+ACFVAILIGLCLTL+ LAIF+KALPALPISITFGLIFYF T ++ PF D ++ Q++I
Sbjct: 9 SREGTEVDLQPASGGGGRAWGESGTEEEEEELKYGAKHVIRLFVPVSLCMLVVVATISSISFYRHTN-TYLVYTPFTDQTVDTGTKVWQSFANAFILMGVIVVMTILLILLYKFRCYKVIHAWLIVSSLLLVFLFAYIYLGEVLRAYNVPMDYLTVALVMWNFGVVGMISIHWKGPLLLQQAYLILVSALMALVFIKYLPDWTAWVVLGVISVWDLIAVLCPKGPLRILVETAQERNEPIFPALIYSSAMVWNVVTMADRDPFYSSQNQHASQSDASSGTSRRPCSTFPRMRGSGRSRRRSQRGSMANSGTLAALGSSQGSAPEVDDLPRQEEEERGVKLGLGDFIFYSVLVGKASSYGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATSSLVQPFADSLAGEQVFI 431
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: gb|KFM74765.1| (hypothetical protein X975_10848, partial [Stegodyphus mimosarum]) HSP 1 Score: 418.698 bits (1075), Expect = 3.348e-143 Identity = 235/417 (56.35%), Postives = 289/417 (69.30%), Query Frame = 0
Query: 11 RDPRRREVQEL----EEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRRRDN--------QRMAAESQX---QELSPPPLQQQ-----------------------QQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
R PR L E+EE + +GAK+VI LF PV+LCM VV T S+T YT+ + YLVYTPF + + + T W +FANA IL+ VI MT++LI+ YK++ +IHGWL +SS MLLFLF+YI+LGEVL+ YN+PMDYIT++ IMWNFGVVGM+ IHW+ PLLLQQ+YLI +SAL+AL FIKYLPN+T W VL IS+W L AVL P GPLRILVETAQERNEPIFP+LIYS+ + + V M+D SD NRR + + AA ++ E P L+ Q V EE++RG+KLGLGDFIFYS+LVGKASSYGDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPISITFGLIFYF T ++ PF D ++S Q+YI
Sbjct: 99 RSPRVHSRPNLQSWDEDEEEELKYGAKHVIKLFIPVSLCMLVVVATTSSITFYTQTN-TYLVYTPFTDQTVDTPTKVWQSFANAFILMGVIVCMTILLILLYKFRWYKVIHGWLIVSSLMLLFLFAYIYLGEVLRAYNIPMDYITVSIIMWNFGVVGMICIHWRGPLLLQQAYLILVSALMALVFIKYLPNWTAWVVLGVISVWDLIAVLCPKGPLRILVETAQERNEPIFPALIYSSAMAWYVT-MSD--SDHTVRNRRHSDGDGNPNEPENTAASNEADIPNETGPHNLEGSNRSSERSRRATGWPSGSGSHPLPSQTEVHTEEDERGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFTTSSLVQPFADSLASEQVYI 511
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: AGB94803.1 (presenilin, isoform D [Drosophila melanogaster]) HSP 1 Score: 398.667 bits (1023), Expect = 3.548e-135 Identity = 226/443 (51.02%), Postives = 291/443 (65.69%), Query Frame = 0
Query: 18 VQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVI-----------------------------------------GMADSSSDPKRPNRRRDNQRMAAESQX----QELSPPPLQQQQQPPVE--------------------------EEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
E+EEE+ + +GA++VI LF PV+LCM VV TI S++ Y D YL+YTPFHE S P W+A AN+ IL++V+ VMT +LI+ YK +C +IHGWL LSSFMLLF+F+Y++L E+L+ YN+PMDY T IMWNFGVVGMMSIHW+ PL LQQ YLIF++AL+AL FIKYLP +T WAVLA IS+W L AVL+P GPLRILVETAQERNE IFP+LIYS+ ++Y+++ G +S P R N+R D +A E++ QE S ++ + +E + +E+RGIKLGLGDFIFYS+LVGKASSYGDW TT+ACFVAILIGLCLTL+ LAI+RKALPALPISITFGLIF F T ++ PFM+++S++Q++I
Sbjct: 88 TNEMEEEQGL-KYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTD-VYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHP-RQNQRDDGSVLATEAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI 527
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: AAN12132.1 (presenilin, isoform B [Drosophila melanogaster]) HSP 1 Score: 398.667 bits (1023), Expect = 3.548e-135 Identity = 226/443 (51.02%), Postives = 291/443 (65.69%), Query Frame = 0
Query: 18 VQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVI-----------------------------------------GMADSSSDPKRPNRRRDNQRMAAESQX----QELSPPPLQQQQQPPVE--------------------------EEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
E+EEE+ + +GA++VI LF PV+LCM VV TI S++ Y D YL+YTPFHE S P W+A AN+ IL++V+ VMT +LI+ YK +C +IHGWL LSSFMLLF+F+Y++L E+L+ YN+PMDY T IMWNFGVVGMMSIHW+ PL LQQ YLIF++AL+AL FIKYLP +T WAVLA IS+W L AVL+P GPLRILVETAQERNE IFP+LIYS+ ++Y+++ G +S P R N+R D +A E++ QE S ++ + +E + +E+RGIKLGLGDFIFYS+LVGKASSYGDW TT+ACFVAILIGLCLTL+ LAI+RKALPALPISITFGLIF F T ++ PFM+++S++Q++I
Sbjct: 88 TNEMEEEQGL-KYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTD-VYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHP-RQNQRDDGSVLATEAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI 527
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: XP_396620.4 (PREDICTED: presenilin-1 [Apis mellifera]) HSP 1 Score: 387.497 bits (994), Expect = 3.622e-131 Identity = 232/427 (54.33%), Postives = 280/427 (65.57%), Query Frame = 0
Query: 14 RRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMY---------------------------------------SVIGMA----------DSSSD--PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
R R ++ EEEE + +GA +VI LF PV+LCM VV TI S+ YT + G YLVYTPFHE S + T AW A AN+ IL++VI MTVILI+ YKYK +IHGWL +SS +LL +FS ++ +VLK YN+PMD TL ++WNFGVVGM+ IHW+ PL LQQ+YLIFISAL+AL FIKYLP +T W VL IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ IMY S G A D+ D +R R+N E Q+ Q QQ P+ EEE RG+KLGLGDFIFYS+LVGKASSYGDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPIS+TFGL FYF T+ I+ PF D+++S Q++I
Sbjct: 79 RSRNYRDEEEEE--LKYGAAHVIKLFVPVSLCMLVVVATISSINFYTTK-GMYLVYTPFHEDSADTSTKAWQAVANSLILMSVIVFMTVILIVLYKYKFYKVIHGWLIISSLLLLSMFSMLYCEQVLKAYNIPMDLYTLGLVLWNFGVVGMICIHWQGPLQLQQAYLIFISALMALVFIKYLPEWTAWVVLGVISIWDLIAVLTPKGPLRILVETAQERNESIFPALIYSSTIMYTATMTYAGYVQTATMTTNDTTASDNTTYTMNNQANNQNNSTSGDAEEGGFTPEWIDTHGDRGARRAQEVRENTLSLTERSRQDNRVARESQGQQVPITEEE--RGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISVTFGLTFYFATRVIVAPFADKLASEQVFI 500
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: XP_016767700.1 (PREDICTED: presenilin-1 [Apis mellifera]) HSP 1 Score: 387.497 bits (994), Expect = 3.622e-131 Identity = 232/427 (54.33%), Postives = 280/427 (65.57%), Query Frame = 0
Query: 14 RRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMY---------------------------------------SVIGMA----------DSSSD--PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
R R ++ EEEE + +GA +VI LF PV+LCM VV TI S+ YT + G YLVYTPFHE S + T AW A AN+ IL++VI MTVILI+ YKYK +IHGWL +SS +LL +FS ++ +VLK YN+PMD TL ++WNFGVVGM+ IHW+ PL LQQ+YLIFISAL+AL FIKYLP +T W VL IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ IMY S G A D+ D +R R+N E Q+ Q QQ P+ EEE RG+KLGLGDFIFYS+LVGKASSYGDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPIS+TFGL FYF T+ I+ PF D+++S Q++I
Sbjct: 79 RSRNYRDEEEEE--LKYGAAHVIKLFVPVSLCMLVVVATISSINFYTTK-GMYLVYTPFHEDSADTSTKAWQAVANSLILMSVIVFMTVILIVLYKYKFYKVIHGWLIISSLLLLSMFSMLYCEQVLKAYNIPMDLYTLGLVLWNFGVVGMICIHWQGPLQLQQAYLIFISALMALVFIKYLPEWTAWVVLGVISIWDLIAVLTPKGPLRILVETAQERNESIFPALIYSSTIMYTATMTYAGYVQTATMTTNDTTASDNTTYTMNNQANNQNNSTSGDAEEGGFTPEWIDTHGDRGARRAQEVRENTLSLTERSRQDNRVARESQGQQVPITEEE--RGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISVTFGLTFYFATRVIVAPFADKLASEQVFI 500
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Match: XP_016767699.1 (PREDICTED: presenilin-1 [Apis mellifera]) HSP 1 Score: 387.497 bits (994), Expect = 3.622e-131 Identity = 232/427 (54.33%), Postives = 280/427 (65.57%), Query Frame = 0
Query: 14 RRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMY---------------------------------------SVIGMA----------DSSSD--PKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
R R ++ EEEE + +GA +VI LF PV+LCM VV TI S+ YT + G YLVYTPFHE S + T AW A AN+ IL++VI MTVILI+ YKYK +IHGWL +SS +LL +FS ++ +VLK YN+PMD TL ++WNFGVVGM+ IHW+ PL LQQ+YLIFISAL+AL FIKYLP +T W VL IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ IMY S G A D+ D +R R+N E Q+ Q QQ P+ EEE RG+KLGLGDFIFYS+LVGKASSYGDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPIS+TFGL FYF T+ I+ PF D+++S Q++I
Sbjct: 79 RSRNYRDEEEEE--LKYGAAHVIKLFVPVSLCMLVVVATISSINFYTTK-GMYLVYTPFHEDSADTSTKAWQAVANSLILMSVIVFMTVILIVLYKYKFYKVIHGWLIISSLLLLSMFSMLYCEQVLKAYNIPMDLYTLGLVLWNFGVVGMICIHWQGPLQLQQAYLIFISALMALVFIKYLPEWTAWVVLGVISIWDLIAVLTPKGPLRILVETAQERNESIFPALIYSSTIMYTATMTYAGYVQTATMTTNDTTASDNTTYTMNNQANNQNNSTSGDAEEGGFTPEWIDTHGDRGARRAQEVRENTLSLTERSRQDNRVARESQGQQVPITEEE--RGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISVTFGLTFYFATRVIVAPFADKLASEQVFI 500
BLAST of EMLSAG00000000448 vs. nr
Match: gi|676433820|ref|XP_009047025.1| (hypothetical protein LOTGIDRAFT_138705 [Lottia gigantea] >gi|556113665|gb|ESP02317.1| hypothetical protein LOTGIDRAFT_138705 [Lottia gigantea]) HSP 1 Score: 458.759 bits (1179), Expect = 1.121e-157 Identity = 223/370 (60.27%), Postives = 277/370 (74.86%), Query Frame = 0
Query: 30 HGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRRRDNQRMAAESQXQELSPP--------PLQQQ--QQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+GA +VIMLF PVTLCMA VV TI SVT YTE+ YL+YTPFH+ +D+ GT W +FANA ILL VI V+T+ L++ YK++C +IHGWL +SS MLLFLFSYI+LGEVL+ YN+PMDY+T+ +MWNFGVVGM+ IHWK PLLLQQ+YLI ISAL+AL FIKYLP++TTW VL + +W L AVL P GPLR+LVETAQERNEPIFP+LIYS +S++ R R Q + + Q ++ P P Q+ P ++EE+RG+KLGLGDFIFY +LVGKASSYGDWNTTLACFVAILIGLC TL+ LAIF+KALPALPISITFGL+F F T ++ PFMD +++ Q+Y+
Sbjct: 49 YGANSVIMLFVPVTLCMAVVVATISSVTFYTEKTDGYLIYTPFHDKTDDTGTKLWQSFANAFILLGVICVLTIFLLLLYKFRCYKVIHGWLIVSSLMLLFLFSYIYLGEVLRAYNVPMDYVTVIILMWNFGVVGMVCIHWKGPLLLQQAYLIMISALMALIFIKYLPDWTTWVVLGVMVVWDLVAVLCPKGPLRVLVETAQERNEPIFPALIYSCKCNTRYSSPMTASTESTRA--RNAVQALNTTNNYQTIADPDRPPGTATPNQRSSTNSQPQTQDEEERGVKLGLGDFIFYGVLVGKASSYGDWNTTLACFVAILIGLCFTLLLLAIFKKALPALPISITFGLVFNFATSSLVQPFMDSLAAEQVYL 416
BLAST of EMLSAG00000000448 vs. nr
Match: gi|961128754|ref|XP_014785183.1| (PREDICTED: presenilin-1-like isoform X4 [Octopus bimaculoides]) HSP 1 Score: 460.685 bits (1184), Expect = 3.382e-157 Identity = 228/379 (60.16%), Postives = 281/379 (74.14%), Query Frame = 0
Query: 32 AKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNRRRDNQ-----------RMAAESQXQELSPPPLQQQQQPPVEEEEED----------RGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
AK+VIMLF PVTLCM VV TI SVT YT+ G YL+YTPFHE +D+ GT W +FANA ILL VIAVMTV+L++ YKY+C +IHGWL +SS +LLF+FSY++LGEVLK YN PMDYIT+A +MWNFGV+GM+ IHWK PLLLQQ+YL+ ISAL+AL FIKYLP++TTW+VL + W L AVL P GPLR+LVETAQ RNE IFP+LIYS+ +++ ++ MAD S PKR + R A ++ + + P + +PP + + RG+KLGLGDFIFY +LVGKASSYGDWNTTLACFVAILIGLC TL+ LAIFRKALPALPISITFGLIF F T+ ++ PFMD ++S Q+YI
Sbjct: 119 AKHVIMLFVPVTLCMIVVVATISSVTYYTQP-GGYLIYTPFHEETDDSGTKVWQSFANAFILLGVIAVMTVVLLLLYKYRCYKVIHGWLIVSSLLLLFMFSYMYLGEVLKAYNAPMDYITVAILMWNFGVIGMICIHWKGPLLLQQAYLLMISALMALIFIKYLPDWTTWSVLGIMVFWDLVAVLCPKGPLRVLVETAQHRNEDIFPALIYSSTMVWQIVTMADES--PKRDSGANSTSTLATDVHSSPARRAIDALGEMENDPNSEANNRPPADRNQRSQGSGEEEEEERGVKLGLGDFIFYGVLVGKASSYGDWNTTLACFVAILIGLCFTLLLLAIFRKALPALPISITFGLIFNFATRGLVRPFMDNLASEQMYI 494
BLAST of EMLSAG00000000448 vs. nr
Match: gi|961128751|ref|XP_014785182.1| (PREDICTED: presenilin-1-like isoform X3 [Octopus bimaculoides] >gi|918293130|gb|KOF70540.1| hypothetical protein OCBIM_22002682mg [Octopus bimaculoides]) HSP 1 Score: 450.669 bits (1158), Expect = 4.011e-153 Identity = 230/411 (55.96%), Postives = 283/411 (68.86%), Query Frame = 0
Query: 32 AKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNR------------------------------RRD-------------NQRMAAESQXQELSPPPLQQQQQPPVEEEEED----------RGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
AK+VIMLF PVTLCM VV TI SVT YT+ G YL+YTPFHE +D+ GT W +FANA ILL VIAVMTV+L++ YKY+C +IHGWL +SS +LLF+FSY++LGEVLK YN PMDYIT+A +MWNFGV+GM+ IHWK PLLLQQ+YL+ ISAL+AL FIKYLP++TTW+VL + W L AVL P GPLR+LVETAQ RNE IFP+LIYS+ +++ ++ MAD S PKR + R D R A ++ + + P + +PP + + RG+KLGLGDFIFY +LVGKASSYGDWNTTLACFVAILIGLC TL+ LAIFRKALPALPISITFGLIF F T+ ++ PFMD ++S Q+YI
Sbjct: 100 AKHVIMLFVPVTLCMIVVVATISSVTYYTQP-GGYLIYTPFHEETDDSGTKVWQSFANAFILLGVIAVMTVVLLLLYKYRCYKVIHGWLIVSSLLLLFMFSYMYLGEVLKAYNAPMDYITVAILMWNFGVIGMICIHWKGPLLLQQAYLLMISALMALIFIKYLPDWTTWSVLGIMVFWDLVAVLCPKGPLRVLVETAQHRNEDIFPALIYSSTMVWQIVTMADES--PKRDSGANSTSTLATDVHSSPATNATSNPEAGTNIYRNDVDAHNLTNSIDSQTARRAIDALGEMENDPNSEANNRPPADRNQRSQGSGEEEEEERGVKLGLGDFIFYGVLVGKASSYGDWNTTLACFVAILIGLCFTLLLLAIFRKALPALPISITFGLIFNFATRGLVRPFMDNLASEQMYI 507
BLAST of EMLSAG00000000448 vs. nr
Match: gi|961128748|ref|XP_014785181.1| (PREDICTED: presenilin-1-like isoform X2 [Octopus bimaculoides] >gi|918293129|gb|KOF70539.1| hypothetical protein OCBIM_22002682mg [Octopus bimaculoides]) HSP 1 Score: 451.055 bits (1159), Expect = 5.057e-153 Identity = 230/411 (55.96%), Postives = 283/411 (68.86%), Query Frame = 0
Query: 32 AKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNR------------------------------RRD-------------NQRMAAESQXQELSPPPLQQQQQPPVEEEEED----------RGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
AK+VIMLF PVTLCM VV TI SVT YT+ G YL+YTPFHE +D+ GT W +FANA ILL VIAVMTV+L++ YKY+C +IHGWL +SS +LLF+FSY++LGEVLK YN PMDYIT+A +MWNFGV+GM+ IHWK PLLLQQ+YL+ ISAL+AL FIKYLP++TTW+VL + W L AVL P GPLR+LVETAQ RNE IFP+LIYS+ +++ ++ MAD S PKR + R D R A ++ + + P + +PP + + RG+KLGLGDFIFY +LVGKASSYGDWNTTLACFVAILIGLC TL+ LAIFRKALPALPISITFGLIF F T+ ++ PFMD ++S Q+YI
Sbjct: 112 AKHVIMLFVPVTLCMIVVVATISSVTYYTQP-GGYLIYTPFHEETDDSGTKVWQSFANAFILLGVIAVMTVVLLLLYKYRCYKVIHGWLIVSSLLLLFMFSYMYLGEVLKAYNAPMDYITVAILMWNFGVIGMICIHWKGPLLLQQAYLLMISALMALIFIKYLPDWTTWSVLGIMVFWDLVAVLCPKGPLRVLVETAQHRNEDIFPALIYSSTMVWQIVTMADES--PKRDSGANSTSTLATDVHSSPATNATSNPEAGTNIYRNDVDAHNLTNSIDSQTARRAIDALGEMENDPNSEANNRPPADRNQRSQGSGEEEEEERGVKLGLGDFIFYGVLVGKASSYGDWNTTLACFVAILIGLCFTLLLLAIFRKALPALPISITFGLIFNFATRGLVRPFMDNLASEQMYI 519
BLAST of EMLSAG00000000448 vs. nr
Match: gi|961128745|ref|XP_014785180.1| (PREDICTED: presenilin-1-like isoform X1 [Octopus bimaculoides] >gi|918293128|gb|KOF70538.1| hypothetical protein OCBIM_22002682mg [Octopus bimaculoides]) HSP 1 Score: 450.284 bits (1157), Expect = 9.834e-153 Identity = 230/411 (55.96%), Postives = 283/411 (68.86%), Query Frame = 0
Query: 32 AKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPKRPNR------------------------------RRD-------------NQRMAAESQXQELSPPPLQQQQQPPVEEEEED----------RGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
AK+VIMLF PVTLCM VV TI SVT YT+ G YL+YTPFHE +D+ GT W +FANA ILL VIAVMTV+L++ YKY+C +IHGWL +SS +LLF+FSY++LGEVLK YN PMDYIT+A +MWNFGV+GM+ IHWK PLLLQQ+YL+ ISAL+AL FIKYLP++TTW+VL + W L AVL P GPLR+LVETAQ RNE IFP+LIYS+ +++ ++ MAD S PKR + R D R A ++ + + P + +PP + + RG+KLGLGDFIFY +LVGKASSYGDWNTTLACFVAILIGLC TL+ LAIFRKALPALPISITFGLIF F T+ ++ PFMD ++S Q+YI
Sbjct: 119 AKHVIMLFVPVTLCMIVVVATISSVTYYTQP-GGYLIYTPFHEETDDSGTKVWQSFANAFILLGVIAVMTVVLLLLYKYRCYKVIHGWLIVSSLLLLFMFSYMYLGEVLKAYNAPMDYITVAILMWNFGVIGMICIHWKGPLLLQQAYLLMISALMALIFIKYLPDWTTWSVLGIMVFWDLVAVLCPKGPLRVLVETAQHRNEDIFPALIYSSTMVWQIVTMADES--PKRDSGANSTSTLATDVHSSPATNATSNPEAGTNIYRNDVDAHNLTNSIDSQTARRAIDALGEMENDPNSEANNRPPADRNQRSQGSGEEEEEERGVKLGLGDFIFYGVLVGKASSYGDWNTTLACFVAILIGLCFTLLLLAIFRKALPALPISITFGLIFNFATRGLVRPFMDNLASEQMYI 526
BLAST of EMLSAG00000000448 vs. nr
Match: gi|762116485|ref|XP_011441079.1| (PREDICTED: presenilin-1-like [Crassostrea gigas] >gi|405958341|gb|EKC24477.1| Presenilin-2 [Crassostrea gigas]) HSP 1 Score: 444.121 bits (1141), Expect = 1.009e-150 Identity = 233/406 (57.39%), Postives = 284/406 (69.95%), Query Frame = 0
Query: 30 HGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHE---LSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSD--------------------------------PKRPNRRRDNQ-----------RMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
+GAK+VIMLF PV+LCMA VV TI SVT YTE+ G YLVYTPFH+ + GT W + ANA ILL VI VMT++L++ YK++C +IHGWL SS MLLFLFSYI+LG VL+ YN+ MDYIT+A +MWNFGVVGM+ IHWK PL LQQ+YLI ISAL+AL FIKYLP++TTW VL + +W L AVL P GPLRILVETAQERNEPIFP+LIYS+ +++SV+GMAD SD +RP R+ R+ +++ + + P ++ EEEEE+RG+KLGLGDFIFY +LVGKASS GDWNTTLACFVAILIGLC TL+ LAIFRKALPALPISITFGLIF F T ++ PF D +S+ Q+YI
Sbjct: 85 YGAKHVIMLFVPVSLCMAVVVATISSVTFYTEK-GGYLVYTPFHDGDKADADTGTKVWQSVANALILLGVICVMTIVLLLLYKFRCYKVIHGWLIASSLMLLFLFSYIYLGVVLQAYNVAMDYITVALLMWNFGVVGMICIHWKGPLFLQQAYLIVISALMALVFIKYLPDWTTWVVLGVMVIWDLVAVLCPKGPLRILVETAQERNEPIFPALIYSSTMIWSVVGMADDGSDKKKKKKKKSKKKPEAATAEPDQVEAELDGGFLEERPTRQLSQSTEETARAVRAARVLGDTENGQRTNSPRNPTREEEEEEEEEERGVKLGLGDFIFYGVLVGKASSNGDWNTTLACFVAILIGLCFTLLLLAIFRKALPALPISITFGLIFNFTTSLLVQPFADRLSASQVYI 489
BLAST of EMLSAG00000000448 vs. nr
Match: gi|189239692|ref|XP_967139.2| (PREDICTED: presenilin homolog [Tribolium castaneum] >gi|1004398157|gb|EFA07178.2| Presenilin homolog-like Protein [Tribolium castaneum]) HSP 1 Score: 439.884 bits (1130), Expect = 1.670e-149 Identity = 237/395 (60.00%), Postives = 291/395 (73.67%), Query Frame = 0
Query: 13 PRRREVQELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSD--PKRPNRRR----------------DNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
P EV EL +EE + +GAK+VI LF PV+LCM VV TI +V Y+ +D YLVYTPFHE S + T WNA AN+ IL+AVI VMTV+LI+ YKY+C IHGWL LSS MLL +FSY++L E+L+ YN+PMDY T+ +MWNFGV+GM+ IHW+ PL+LQQ+YLIF++AL+AL FIKYLP +TTWAVLA IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ MY+ MA S+D P R R DN + E+ P + + + +EEE+RG+KLGLGDFIFYS+LVGKASSYGDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPISITFGLIFYF TKEI++PF D +++ Q++I
Sbjct: 71 PVDYEVAELRDEEEELKYGAKHVIKLFAPVSLCMVVVVATISAVNFYSVKD-MYLVYTPFHEESSDTSTKVWNAAANSLILMAVIVVMTVLLIVLYKYRCYKTIHGWLILSSLMLLTVFSYLYLEEILRAYNIPMDYPTIVLLMWNFGVMGMVCIHWQGPLVLQQAYLIFVAALMALVFIKYLPEWTTWAVLAVISVWDLVAVLMPKGPLRILVETAQERNEQIFPALIYSSTYMYAYTSMATPSNDENPPRGAAARSSADSTEEHGFTQDWVDNHSSRVAQRRLEVHDVP-RGAPRTQIHQEEEERGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATKEIVSPFADSLANEQVFI 463
BLAST of EMLSAG00000000448 vs. nr
Match: gi|1133416830|ref|XP_019881318.1| (PREDICTED: LOW QUALITY PROTEIN: presenilin homolog [Aethina tumida]) HSP 1 Score: 434.876 bits (1117), Expect = 9.204e-148 Identity = 233/382 (60.99%), Postives = 281/382 (73.56%), Query Frame = 0
Query: 19 QELEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSS-----------DPKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
QE EEEE + +GAK+VI LF PV+LCM VV TI SV Y+ +D Y +YTPFHE S T WNA AN+ IL+AVI MTV+LI+ YKY+C +IHGWL +SS MLL +FSY++L E LK YN+PMDYITL FIMWNFGV+GM+ IHW+ PLLLQQ+YLIF++AL+AL FIKYLP +TTW VL IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ MY+ MA D +N + E+ P Q + +++EE+RG+KLGLGDFIFYS+LVGKASSYGDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPISITFGLIFYF TKEI++PF D ++S Q++I
Sbjct: 69 QETEEEE--LKYGAKHVIKLFAPVSLCMVVVVATISSVNFYSRKD-VYFIYTPFHEESPETSTKVWNAIANSFILIAVIITMTVLLIVLYKYRCYKIIHGWLIVSSLMLLSIFSYLYLEETLKAYNIPMDYITLLFIMWNFGVMGMLCIHWQGPLLLQQAYLIFVAALMALVFIKYLPEWTTWGVLGVISIWDLVAVLTPKGPLRILVETAQERNEQIFPALIYSSTYMYAYTAMATGDDSSTITTSRSSSDHGFTQDWIENHANRVAQRQLEVHDVPSGQPRTQIHQQDEEERGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATKEIVSPFADSLASEQVFI 447
BLAST of EMLSAG00000000448 vs. nr
Match: gi|755890129|ref|XP_011294721.1| (PREDICTED: presenilin homolog isoform X2 [Musca domestica]) HSP 1 Score: 436.802 bits (1122), Expect = 1.405e-147 Identity = 230/456 (50.44%), Postives = 298/456 (65.35%), Query Frame = 0
Query: 5 GEEVRIRDPRRREVQE-----------------LEEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMA-------------------------------------------------DSSSDPKRPNRRRDNQRMAAESQXQELSPPPLQQQQQPP-----VEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
G E+R R R+ +E +EEEE V+ +GA++VI +F PV+LCM VV TI S+T YT D YL+YTPFHE SD+ GT WNA AN+ ILL+V+ VMT++LI+ YK +C +IHGWL LSSFMLLF+FSY++L E+L+ YN+ MDY T I+WNFGV+GM++IHW++PL LQQ+YLIF+SAL+AL FIKYLP +T WAVLA IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ I+Y+ +G S+ D + R+ + Q ++S + + + Q+ P + E +E+RGIKLGLGDFIFYS+LVGKASSYGDW TT+ACFVAIL+GLCLTL+ LAI+RKALPALPISI FGL F +T I+ PFM+E+S +Q++I
Sbjct: 57 GVEIRSRGGGHRDGEENPNDGEPGPSSQTQPPTVEEEEQVLKYGAQHVIKIFAPVSLCMLVVVATINSITFYTYTD-TYLLYTPFHEQSDDKGTKLWNALANSLILLSVVVVMTIVLIVLYKKRCYRIIHGWLILSSFMLLFIFSYLYLEELLRAYNVAMDYPTTLLILWNFGVMGMIAIHWQSPLKLQQAYLIFVSALMALVFIKYLPEWTAWAVLAAISIWDLIAVLTPKGPLRILVETAQERNEQIFPALIYSSTILYTFMGTTGGPQRNNNSSGSNSPNSPHTSQTSSTSVSRQTGNTATNAEEAAGFTEEWSSNLDERVARRQIEVQASTSDSANRSTNYRTVTAQEDRPHLGSNMTEAQEERGIKLGLGDFIFYSVLVGKASSYGDWATTIACFVAILVGLCLTLVLLAIWRKALPALPISIFFGLFFCLITSVIVKPFMEELSDQQVFI 511
BLAST of EMLSAG00000000448 vs. nr
Match: gi|1080043845|ref|XP_018563049.1| (PREDICTED: presenilin homolog [Anoplophora glabripennis]) HSP 1 Score: 434.106 bits (1115), Expect = 3.372e-147 Identity = 235/380 (61.84%), Postives = 285/380 (75.00%), Query Frame = 0
Query: 22 EEEEFVVNHGAKNVIMLFTPVTLCMAXVVXTIXSVTXYTEEDGNYLVYTPFHELSDNPGTIAWNAFANAGILLAVIAVMTVILIISYKYKCSWLIHGWLFLSSFMLLFLFSYIFLGEVLKTYNLPMDYITLAFIMWNFGVVGMMSIHWKAPLLLQQSYLIFISALLALFFIKYLPNYTTWAVLAXISLWXLFAVLAPFGPLRILVETAQERNEPIFPSLIYSAGIMYSVIGMADSSSDPK-RPNRRRDNQRMA-----------AESQXQELSPPPLQQQQQPPVEEEEEDRGIKLGLGDFIFYSILVGKASSYGDWNTTLACFVAILIGLCLTLMFLAIFRKALPALPISITFGLIFYFLTKEIITPFMDEMSSRQIYI 389
EEEE + +GAK+VI LF PV+LCM VV TI SV+ Y+ +D YLVYTPFHE S T AW A AN+ IL+AVI +MTV+LI+ YKY+C IHGWL +SS MLL +FSY++L E+L+ +N+PMDY TL FIMWNFGV+GM+ IHW+ PLLLQQ+YLIF++AL+AL FIKYLP +TTWAVLA IS+W L AVL P GPLRILVETAQERNE IFP+LIYS+ MY+ MA P R +R + A+ Q + P + + Q EEE+RG+KLGLGDFIFYS+LVGKASSYGDWNTTLACFVAILIGLCLTL+ LAIF+KALPALPISITFGLIFYF TKEI++PF D ++S Q++I
Sbjct: 85 EEEE--LKYGAKHVIKLFAPVSLCMVVVVATISSVSFYSMKD-MYLVYTPFHEESPESSTKAWMAAANSLILMAVIVLMTVLLIVLYKYRCYKTIHGWLIISSLMLLSIFSYLYLEEILRAFNIPMDYPTLLFIMWNFGVMGMIVIHWQGPLLLQQAYLIFVAALMALVFIKYLPEWTTWAVLAVISIWDLIAVLMPKGPLRILVETAQERNEQIFPALIYSSTYMYAYTSMASGDEVPNVRTSRSSADHGFTQEWVENHADRFAQRQIEVHDVPSGRPRVQVVAASEEEERGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATKEIVSPFADSLASEQVFI 461 The following BLAST results are available for this feature:
BLAST of EMLSAG00000000448 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
Pagesback to top
BLAST of EMLSAG00000000448 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 11
Pagesback to top
BLAST of EMLSAG00000000448 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 1
BLAST of EMLSAG00000000448 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 25
Pagesback to top
BLAST of EMLSAG00000000448 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 22
Pagesback to top
BLAST of EMLSAG00000000448 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
Pagesback to top
BLAST of EMLSAG00000000448 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 0
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s106:189612..190849- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000000448-683214 ID=EMLSAG00000000448-683214|Name=EMLSAG00000000448|organism=Lepeophtheirus salmonis|type=gene|length=1238bp|location=Sequence derived from alignment at LSalAtl2s106:189612..190849- (Lepeophtheirus salmonis)back to top Add to Basket
|