Query:  375 VMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSD------YQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHI-------FDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPRE 584
            V A+ V ++  G +T   T+ +A   LAK P+ QKKLQ+EI+R    +  +E+++    +Q M YL   + E+ RL+     I+R    +      + +P   +V+   +   +   +F     F PE  +       F    + HN+       L +PFG G R C G + A  E       L ++F L +   +   +    + +L  S D + ++A  R+
Sbjct:  337 VKASVVDYITAGVDTIGNTVIFALLLLAKYPEKQKKLQAEIER----VLGSENYITKENIQEMKYLKGCVNESFRLYPTASQIARILDEEIITSNGHSLPPGSVVLCHQRIASLQEQNFTRAKEFIPERWLEXEAVTEFGTTNYAHNKS------LVMPFGFGKRICPGKKLAEQEIYIMTAKLMKNFNLRLHDASDFDVEF--RFLLMPSLDNLQIQATSRD 547          

Query:  367 QSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRK-MKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSR-HQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLD 552
            +S L  + V+   +  L  G  TT   L +  Y LAK P +Q+KL  EI R  +     T +HL+     S T + +V    L             +S Y++P       +G  V +     + +  F+ +P I  PER+   +  S  H Y +LPF  G R C+G R A  +    +V+L R F  +
Sbjct:  387 KSDLSLANVITLIISLLTDGLSTTVPVLLFNLYSLAKNPSSQEKLYEEIQRVVKNDSDITTAHLKEILFPSGTEVSRVTDHDL------------ILSGYEVP-------KGTRVDLNHGPINKSEEFYEDPLIHKPERWLRGKFPSNIHPYQYLPFSHGTRMCIGRRLAEQDMNVVMVTLLRQFRFE 555          

Query:  338 NDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDRE-HRKMKYTESHLEYSTLQSMTYLDQVIQEALRL-HTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDV 553
            ND +D+ L  M                N  ST  +  + +  +     G ETT TTL +A   ++     Q+K   EI+     +M   E       ++++ Y    + E  RL +T    +    + D +I   D V+ +G      +  FH +P  F  P  F+P+R+ H +   +    F+PFG G R C+G+  A  E     V L + F + V
Sbjct:  162 NDFMDVYLIEMK--------------KNVDSTFSKKQLASLCIDLFLAGAETTNTTLVWALLYMSLYEGVQEKCAEEINSVLGSRMPQEED------MKNLPYTIATLNEIQRLCNTAPASLPHKNLKDIKI--GDYVVPKGTLFLANLIGFHHDPNIFENPQQFNPDRWLHYKSCPQQ---FVPFGFGKRICMGVSLAKKELYYFFVMLIKMFIIRV 354          

Query:  439 YLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERF 505
            Y   VI+EALR++ P  +  R C  D ++  D + IK+G  + +P+   H  P  FP P    PERF
Sbjct:   15 YTSSVIKEALRIYPPATLHLRICAKDTEV--DGIPIKKGTAIELPIYVSHYIPELFPSPEELKPERF 79          

Query:  388 ETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHL-EYSTLQSMTYLDQVIQEALRLHT--PLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTL 551
            ETT T+L +A   +   P+   K++ E++         E +L + S +  + Y    + E +R  +  P+G       +D ++  +  V+ +   V   + + HMNP  +  P  F PERF + +        F+PFGVG R CLG R A  E      SL   F L
Sbjct:  312 ETTRTSLLWAIVFMLHNPKILSKVRDELNS-----VVGEDNLPQLSDMIKLPYTRATLYEIMRRSSVVPMGTTH---ATDREVQFEGFVLPQNSHVIPLIHAVHMNPKNWENPEEFRPERFINKEGVLFKPEHFMPFGVGQRKCLGDRLAEQEFFLFFTSLVHVFDL 470          

Query:  192 GDQWKDLRTTFTPIFTS--GKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAH-KILMRNPGQFWRLIL---VRIPGMKALMRSL--GISVFKGHELVLLHEIVVQTLKYRKETHI-HRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEID---REHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVS-DYQIPGDDLVIKRGQEVHIPVASFHMNPAF-----FPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLG 530
            G++WK LR   +  F S  G    +    D    ++VA +   +    P+ I ++   F +  +    + V  + ++ G P    Q  + K+L+  P      I+   + IP ++ +   +   ++ F+    +LL +IV +    RK+     +   +D+ L+A                 +N    +E L+M     FL  G ET++ TL      +   P  Q+   SEI    ++  ++K  + HL       + Y D V+ E  R  TP  +    C + D ++ G D         ++PV   ++N        +  P IF+P RF + +        F+PFG G R C+G
Sbjct:  134 GERWKFLRRFSSSAFKSLSGGASGLNQNFDLEVSEIVAXLRGKAKSPDPI-IRNVNIYFDIPILNIIWWLVAGRRYKYGDPAIQKQFDYLKVLLEEPFIAPLTIIPFALYIPPLRKIYNRIRNAMNSFR----ILLSKIVEER---RKDNFTDEKRGFIDLFLKAQLDD------------KDNPYLSNEDLIMCCQDFFL-AGAETSSKTLCTFILYMVLYPNIQENAASEIRDAIQKDTQIKSKDRHL-------LPYTDAVLMEVRRYATPFPITPFRCSNKDIRVNGFD------XPANVPV-QVNLNGVLRSKYCWKAPDIFNPSRFLNEKGAVEIPNAFMPFGFGRRRCIG 455          

Query:  408 QKKLQSEI-DREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERF-NHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDV 553
            QKK + EI D+     K T+       +  + Y    + E  RL + +G +S    +   I  +   I  G E++    +FH +P FFPEP  F PERF   +  + +    FLPFG+G R C+G   A  +     + + ++  + V
Sbjct:  273 QKKCKEEIKDKLQGDEKPTQD-----CISELPYTHATLMEVQRLAS-VGPMSLPRYTTKDIDVNGYSIPEGTEIYSNFMAFHRDPDFFPEPLEFKPERFLTEDGSRVKKDEHFLPFGLGRRICMGESLARHQLIIFFIMILQNLNISV 414          

Query:  382 FLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEY--STLQSMTYLDQV--IQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAI---LGNSQDPIYLRAVPR 583
            F   G ETT+TTL +    +      Q K   EI +        E  ++    TL +++ + +   I  A  +H  L  I  G    Y IP       +G  V      FHM+P  FP PH F+P RF    +  +    F+P+G G R C+G   A  +     V + +++ + V    P   R +PK     + +  DP Y+    R
Sbjct:  288 FFLAGSETTSTTLLWIILLMCLHNDIQLKCYQEISQNIGNNFPREEDMKMLPFTLATISEVQRYANIAPASLVHKVLQTIRVG---KYLIP-------KGTSVIANYHKFHMDPKVFPHPHEFNPYRFYKVPKPEQ----FVPYGFGKRICMGKSLAKKQLFYFFVMIVQNYIIRVPKDNP---RPDPKKCTMGITSVPDPFYVNIQKR 479          

Query:  103 LHGHCMHSKVNQV--DFVRKQADAF--TGCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITK---ISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKIL--MRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQST---LDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPG-DDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRA 580
            L+G+ +  + N+V  DF     + +  +G  + G +    P   + D  L ++IL++DF +F DR        F++G    D   T+ +  L G +WKD+R   TP FTSGKMK M P +  V ++ V  IT+    + +G  ++I +L  +F+ D +  CAFG+E  + ++   + F  +  K+   MR+ G+   + +   P + + +R + +     H+  +   +V  T+  R+  +  RND +++++E         +K  GR   +N      +D   + A   VF   G+ET+++T+SY  YELA+    Q +L++EI      ++  E  L Y ++++MTYL+QVI E LRL+T +  + R  ++DY +PG + LVI++G +V IP  ++H +   +P P  FDPERF+  +  +R    +LPFG GPR+C+GMRF  ++A+  L  +   F + VC  T   L+ +P +I+  +   IYLR 
Sbjct:   39 LYGNMVGFRKNRVMHDFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQ------FHNG---RDDPLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSD-FRTMGQKVFTDMRH-GKLLTMFVFSFPKLASRLR-MRMMPEDVHQFFM--RLVNDTIALRERENFKRNDFMNLLIE---------LKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEI---QTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRV 503          

Query:  129 KYYGTFAFGDPVLVVTDPCLVQDILVRD-FDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYR--KETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPRE 584
            K +G +    PVL +TDP +++ +LV++ +  F +R         N G      +  K I++   ++WK +R   +P FTSGK+K M P+I+     +V  + + S  G+P  + D+F  +SMD +   +FGV   S  + Q + F++   K+L  +      L +   P +  L  +L +S+F   +++   +  V+ +K    KE    R D + +M+ + ++           K  ++   L +  ++A +V+F+F GYETT++ LS+  Y LA  P  QKKLQ EID         ++H  Y TL  M YLD V+ E LRL+   G + R C +D +I G  + I +G  V IP  + H +P ++PEP  F PERF+   + + + Y++LPFG GPR+C+GMRFAL+  K AL  + ++F+   C  T   L+L+ + +L   + P+ L+ V R+
Sbjct:   70 KLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRR--------NFGPV---GILKKAISISEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVITATSFGVNVDSLNNPQ-DPFVEKVKKLLKFDIFDPLFLSVTLFPFLTPLFEALNVSMFP-RDVIDFFKTSVERMKENRMKEKEKQRMDFLQLMINSQNS-----------KVKDSHKALSDVEIVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALP----NKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEING--VFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSFQPCKETQIPLKLSKQGLL-QPEKPLLLKVVSRD 497          

Query:  127 GCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQM-------------VAEITKISYHGQ--PVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAM--STPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGD-DLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAI 568
            G KY G F F +PVLV+ DP L++ + V+DF++F+D             + +++ ++ K +  LRG +WK++R+T +P FTS KMK M  L+    +Q+               E  KI   G    V++ DL+ +++ D +A  AFG+   S ++ + N F Q+   +   N G   + I +       LM+ L +             +V  T+  RK   I R D++ ++++A   +   E+  + +G+  S  +   D+  + A AV+F F G++T +T L +  + LA  P  Q +LQ EID+    ++  +  L Y  + SM YLD V+ E+LRL+ P     R CV +Y++P +    ++ G  V IP+ + H +P ++P P  FDPERF+   + +   + +LPFG GPR+C+G RFAL+E+K ALV L   F L V S TP  +++  K  
Sbjct:   72 GYKYGGMFEFMNPVLVLRDPELIKMVTVKDFEYFLDHRAPI--------SEEAEPMFGKNLFNLRGHRWKEMRSTLSPAFTSSKMKNMFVLVSECGKQLGEFLMECSRDKNKKTEGCKIEREGDLLTVELKDLYTRYTNDVIATSAFGIGCDSLKNPK-NEFFQMGKDV--TNFGGIRQFIFLGYLFSPRLMKYLNLKFLSSKATEFFRFLVHNTMDTRKTKGIIRPDMIHLLMQAKEGTLKSEENGETNGKIAS--KPKWDDDDLTAQAVLFFFAGFDTASTLLCFMSHLLATNPDVQNRLQDEIDQS---LEENDGKLTYEAIHSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPMEPSYTLEPGDAVWIPIYAIHHDPKYYPNPEKFDPERFSDENKDNIKPFTYLPFGSGPRNCIGNRFALMESKIALVHLLCRFNLKVVSKTPIPIKITKKGF 515          

Query:  129 KYYGTFAFGDPVLVVTDPCLVQDILVRD-FDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYR-KETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPR 583
            K +G +    P+L +TDP +++ +LV++ +  F +R       +  +            I+L   +QWK +RT  +P FTSGK+K M P+I      +V  + K +  G PV++ D+F  +SMD +   AFGV   S  +   + F++ +  +L   P   + L ++  P +  +   L I++F    +    + V +  + R  +  ++R DL+ +M+ + ++           K  +N   L +  ++A + +F+FGGYETT++TLS+  YEL   P  Q+KLQ EID         ++   Y  L  M YLD V+ E LR+    G + R C  D +I G  + I +G  V +P+   H NP  +PEP  F PERF+ N + S + Y++LPFG GPR+CLGMRFA++  K ALV + ++F+   C  T   L+L  +  L   + P+ L+ VPR
Sbjct:   70 KMWGFYEGRQPMLAITDPDIIKTVLVKECYSVFTNRRIFGPMGIMKYA-----------ISLAWDEQWKRIRTLLSPAFTSGKLKEMFPIIGQYGDMLVRNLRKEAEKGNPVNMKDMFGAYSMDVITGTAFGVNIDSLNNPH-DPFVEHSKNLLRFRPFDPFILSIILFPFLNPVFEILNITLFPKSTVDFFTKSVKKIKESRLTDKQMNRVDLLQLMINSQNS-----------KEIDNHKALSDIELVAQSTIFIFGGYETTSSTLSFIIYELTTHPHVQQKLQEEIDATFP----NKAPPTYDALVQMEYLDMVVNETLRMFPIAGRLERVCKKDVEIHG--VTIPKGTTVLVPLFVLHNNPELWPEPEEFRPERFSKNNKDSINPYVYLPFGTGPRNCLGMRFAIMNIKLALVRILQNFSFKPCKETQIPLKLYTQG-LTQPEQPVILKVVPR 496          

Query:  130 YYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNY-FLQLAHKIL-MRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAM---STPPEDGIKPSGRKYSNNQSTLDE---SLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKA 567
            + G + F  P +++ DP +++ +LV+DF+ F DR+             +SD+L ++ +  L G  WK LR   +P FTSG+MK M PL++  C + + +  K + + + +++ +   K++ D ++ CAFG+E+ S +   PN  F +   KI        F  + L   PG   L++ L  + F       L ++   T+ +R+   I R+D +D++++     +   EDG         +  S L E     +++   +F   G+ET ATTLS+  YEL+  P  Q +L+SEI      MK +     Y  +  M YL  V+ E LR + PL ++ R C+ DY++PG DL+I+R   V I +   H +P ++P P  +DPERF+   ++ R  Y +LPFG GP +C+G+RF  +  K ALV +   F +  C  TP  L L+ ++
Sbjct:   76 FVGFYIFARPAILIKDPNIIKHVLVKDFNAFSDRHA---------SAAESDTLGSQNLFTLNGAPWKYLRVKLSPTFTSGRMKKMYPLVES-CAKQLQDYLKENCNTKAIEVKETTAKYATDVISTCAFGIESNSLK--DPNAEFREFGRKIFEFTRYRTFEVMALFFSPG---LVKFLNGNFFTKETTEFLRKVFWDTINFRESNKISRDDFMDLLIQLKNKGTIDNEDGEVTEKVDKIDKDSHLFEFTGDNLVSQPALFFTAGFETNATTLSFTLYELSLQPDLQNRLRSEI---AGVMKTSNGKPTYEDVFGMPYLHMVVSETLRKYPPLPLLDRVCLQDYKVPGTDLIIERDTPVFIALLGLHRDPQYYPNPERYDPERFSEENKRQRKAYTYLPFGEGPHNCIGLRFGYMAVKTALVHMLAEFEVKPCKDTPIPLELSTRS 503          

Query:  129 KYYGTFAFGDPVLVVTDPCLVQDILVRD-FDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYR-KETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGV-ISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPRE 584
            K +G +    PVL +TDP +++ +LV++ +  F +R                       I++ + D+WK +R+  +P FTSGK+K M+P+I    + +V  + + +  G+P+++ D+F  +SMD +   +FGV   S  + Q + F++   K+L  +    + L +   P +  ++ +L IS+F       L + + +  + R K+TH HR D + +M+++ ++           K + +   L +  ++A +++F+F GYETT++TLS+  YELA  P  Q+KLQ EID     +   ++   Y T+  M YLD V+ E LRL  PL + + R C  D +I G  + I +G  V IP  + H +P ++ EP  F PERF+ N + +   Y++ PFG GPR+C+GMRFAL+  K AL+ + ++F+   C  T   L+L    +L  ++ PI L+  PR+
Sbjct:   70 KMWGIYDGRQPVLAITDPNIIKTVLVKECYSVFTNRRPFGPVGFMKSA-----------ISIAQDDEWKRIRSLLSPTFTSGKLKEMVPIIAQYGEVLVRNLRREAEKGKPINMKDIFGAYSMDVITGTSFGVNIDSLNNPQ-DPFVESTKKLLRFDFLDPFFLSITIFPFLTPILEALNISMFPRDSTSFLRKSIKRIKESRLKDTHKHRVDFLQLMIDSQNS-----------KETESDKALSDLELVAQSIIFIFAGYETTSSTLSFIMYELATHPDVQQKLQEEID----AVLPNKAPATYDTVLQMEYLDMVVNETLRLF-PLAMRLERVCKKDVEING--VFIPKGVVVMIPSYALHYDPKYWTEPEKFLPERFSKNNKDNIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLRLGGLL-QTEKPIVLKVEPRD 497          

Query:  129 KYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLR 579
            +Y G F F    L + D  L++DI++RDF  F DR       LF++   + D L T  +  L G +W+ LR   T +FTSGKMK M P +  V +++             ++  DL  +F+ D +  CAFG+E  S Q  +   F ++   +          L+   +     L R L   +F+        + V QTL YR+  +IHRNDL+ +++E      E+G+K            L    + A A+VF   G++T++TT+S+  YELA  P  Q++L+ E+      +K     L Y ++Q M YLDQV+ E LR +  L  + R    +YQIP  +L+++ G ++ IPV S H +P  +P+P  FDP RF   + ++RH + +LPFG GPR+C+G RF  L+ K  LV L R F       T   L+ + +  L ++Q+ ++LR
Sbjct:   68 RYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADR------GLFHN--VRDDPL-TGNLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQ---ACRLQVGEIEAKDLCARFTTDVIGSCAFGLECNSLQDPESQ-FRRMGRSVTQEPLHSV--LVQAFMFAQPELARKLRFRLFRPEVSEFFLDTVRQTLDYRRRENIHRNDLIQLLMEL----GEEGVK----------DALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEV---LAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQEGVHLR 486          

Query:  130 YYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKIL-MRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDR--EHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPK 566
            Y G FAF  P L+V D  +V++ILV+D  +F+DR  +   SL          L    I  LRG +WK +RT+ TP FT+GKMK M  L+D   QQ+V  I K +    PV + D  E+F+MD  A CAFG+E  S Q  +   F  L H+I  +        L     P ++   R   + +        + +IV + +  R++T   RNDL+D ++E  ++                 S LD    +A A  FL  G+ T++ TL++A YEL+     Q   ++EI    EH K K T     Y +++ M YLD V+ E LR +  +  + R C  DY +   DL++  G  V+IPV + H +  +FP P  FDPERF+   +Q+   + ++PFG GPR+C+GMRF  ++ KAAL+ +  +F +  C  T   L ++PK
Sbjct:   76 YVGIFAFDQPALLVNDLEIVKNILVKDSRNFIDRMVKVDESL--------SPLNANAIFALRGQKWKHVRTSLTPTFTTGKMKNMFYLVDKCGQQLVLFIEKFAKAENPVAVKDAVERFTMDVTAMCAFGIECNSLQDPKAE-FSNLLHRIFQLSFTSAVANLATFFAPWVQNFFR---LKLMDSEIEDRIRDIVWRAVHLREKTGEKRNDLLDYLMELRTS---------------ETSKLDGDDFVAQAFGFLVAGFHTSSMTLTFALYELSVHQDIQTTARTEIKDVLEHHKKKVT-----YYSIKDMKYLDMVVNETLRKYPAIPFLDRRCQEDYPL-TQDLMLPAGTGVYIPVYALHHDSKYFPSPAKFDPERFSEKNKQNIPHFAYMPFGEGPRNCIGMRFGSMQVKAALIHILSNFEVSPCKETRIPLIIDPK 482          

Query:  132 GTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQ----PVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRA 580
            G + F     ++TD   ++ ++++DF +F DR            T   D   T  +  L G++W+ +R   TP+FTSGK+K M  +I  V  ++   + K     +     V+I DL  +F+ D +  CAFG+E  S Q      F Q   +I  R   +   L+   I     L R L I V            V  T+ YR +  I RND ++ M+E  +   E   K  G   S+   TL++  + A A VF   G+ET+++T+S   YELA  P  Q++L+ EI+     +   E  L Y  L  MTYLDQV+ E LR H  L  + R    DYQIP  D+V+ +G    IPV + H +P  +PEP  FDP RF+  + ++RH   +LPFG GPR+C+G+RF  ++AK  LVSL R F   V + T   L  + K+ L  + D IYL+ 
Sbjct:   71 GMYTFFKRTALITDLDFIKQVMIKDFSYFQDRGA---------FTNPRDDPLTGHLFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCARFTTDVIGSCAFGLECNSLQDPSAE-FRQKGREIFTRR--RHSTLVQSFIFTNARLARKLRIKVLPDDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGL-TLEQ--MAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGE--LNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYLKV 506          

Query:  129 KYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYR-KETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGV-ISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPRE 584
            K +G F    P+LV+TDP +++ +LV+          E  +   N        +    +++   +QWK +RT  +P FTSGK+K M P+I      +V  + K +  G+ V++ D+F  +SMD +   +FGV   S  + Q + F++ A K+L  N    + L +V  P +  +   L I++F    +  L + V +  + R K+    R D + +M+ + ++           K ++N   L +  +MA +V+F+F GYETT+ TLS+  Y LA  P  Q+KLQ EID         ++   Y  L  M YLD V+ E LR+  P+ V + R C  D +I G  + I +G  V +P+   H +P  +PEP  F PERF+   + S + Y++LPFG GPR+C+GMRFA++  K A+V + ++F+   C  T   L++N + ++   + PI+L+ V R+
Sbjct:   70 KMWGVFEGKQPLLVITDPDVIKTVLVK----------ECYSVFTNRRVFGPMGIMKNAVSVAEDEQWKRIRTLLSPTFTSGKLKDMFPIIGKYGDVLVRNLRKEAEKGKSVNMKDIFGAYSMDVITSTSFGVNIDSLGNPQ-DPFVENAKKLLRFNILDPFLLSVVLFPFLVPIFEVLNITMFPKSAVDFLTKSVKRIKESRLKDNQKPRVDFLQLMINSQNS-----------KETDNHKALSDQELMAQSVIFIFAGYETTSNTLSFLLYILATHPDVQQKLQEEIDATFP----NKAPPTYDVLAQMEYLDMVVNETLRMF-PIAVRLDRLCKKDVEIHG--VSIPKGTAVTVPIFVLHRDPQLWPEPEEFRPERFSKKNKDSINPYVYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFSFKPCKETQIPLKINSQGLI-RPEKPIFLKVVLRD 497          

Query:   11 IVLVLLFFAIYLKLTRNNEYWRNRGIPYVPNQFPTGSSPFTDKSVLTGKMQCDNSCCLRPGRPRSDVGGEENLAEGVPRAIRPILTVEGSPRLHGHCMHSKVNQVDFVRKQADAFTGCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQS--DSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLIL-VRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKPS----GRKYSNNQS---------TLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPRE 584
            I +V +F   Y+K     +YW +  +P+V   FP GSSP       T   Q  N   L   + R           G P                                        K YGT+ F +P++ + DP L + I+V+DFDHFVDR GE +A    H TT    D LW +Q+T LRGDQWK  R  FTPIFT GK+K M+  I  V   +V  I + +  G P ++ + F +FSMDT+A CAFGV+A SFQ  +  + +  A  +   +P    + +L V +P  +AL+  LG+ + K    + L++I+ QT+ +R  T   RNDLVD+M++AM   P+    P       ++  +            +DE  ++A A+V L  GY+TTA TL+ A + LA+ P  Q+KL  EI      M+  + + +Y+ +QS+ YLD V+ E LR++  LG+ISR C  DY IPG ++ +K GQ+ HI V++ HMNP  +P+P  FDPERF    + +RH Y FL FG GP++C+GMRFALLEAK AL  + R +    C  T  +  L+P +IL   ++P+ ++   R+
Sbjct:    7 IGVVCIFVYYYVKFHHTWKYWEHHNVPFVKPSFPFGSSPTISWETFTSP-QNFNQTALNEAKKR-----------GFP----------------------------------------KVYGTYFFHNPIISICDPELAKHIMVKDFDHFVDRQGEFLAE---HATTSHLVDQLWGRQMTALRGDQWKATRNAFTPIFTGGKLKGMIHFIHEVTHDLVTSIGQEADRGTPFELKEKFGRFSMDTIASCAFGVKANSFQEDKSTFAMN-AGAMFRNSPMDLMKFVLLVAVPRGRALLECLGVPLQKKAPTMFLYDIITQTVDHRLRTKTRRNDLVDLMIDAMKADPQSSNHPEEPVEDSQFDKDAKLNAPDFQPLNVDEMTLVATAMVILVAGYDTTAQTLAIASFHLARNPDIQEKLHQEIMDAVATMEDDKPYPDYNLIQSLPYLDMVLHETLRINPALGLISRTCTKDYIIPGTNIPLKCGQDAHIYVSAIHMNPDIYPDPKKFDPERFTKESKANRHPYSFLGFGQGPKNCIGMRFALLEAKLALFGVLRSYKFVTCPETIDTYTLDPSSILATPKEPLLVKVEKRK 540          

Query:   92 RPILTVEGSPRLHGHCMHSKVNQVDFVRKQADAFTGCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPP--EDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPR 583
            +P      SP    +    K N  +  + QA A    K+YG + FG P L+V DP + + ILV+DFDHFVDR GET   L   G    D LW  Q+T LRGD+WK  R TFTPIFT+GK+K M+  I  V   +V  + + +  G+P ++ + F KFSMDT+A CAFGV A+SF+  + + F + A  +   +  +  + I+  IPG K +++ L I + K +  +  + ++  T+ +R ET   RNDL+D+M++AM      +D  + S   +       DE  ++A A+V L  GY+TT+ T++   Y +A+ P  Q+KL  EI     +MK  + H +Y+ +QS+ YLD V+ E LR +  LG+I R C  +Y IP  ++V+ +G EVHI   + H NP  +P P  +DPERF    + +RH Y FL FG GPR+C+GMRFALLEAK  L ++ R +       T   L L+PKA L   ++P+ ++AV R
Sbjct:   36 QPEFPFGSSPMFGWNSFTQKYNMNELAKNQAIALGFPKFYGNYIFGTPNLIVCDPEMAKHILVKDFDHFVDRQGETFTKLLEGGHF-VDQLWINQMTALRGDKWKSTRATFTPIFTAGKLKGMIKFIHEVTNDLVKSVGEEAKTGKPFELKEKFGKFSMDTIATCAFGVNAKSFED-ESSIFAKNAKAMFRSSGEEILKFIIAMIPGGKVVLKLLDIPINKKYITLFFYNVIRNTIMHRMETKTRRNDLIDLMIDAMKAENCNKDDTEDSELDHDLRFKQTDEVTMVATALVILVAGYDTTSQTMAITSYFMARNPDIQEKLYQEIMECVGEMKDEKGHPDYNQIQSLPYLDMVLHETLRFNPLLGLIGRACTKNYNIPDTNIVLMKGNEVHINAMAIHHNPDIYPNPEEYDPERFTKEAKANRHPYAFLGFGQGPRNCIGMRFALLEAKLGLFAVLRKYKFVSTPETEEKLTLDPKAFLSVPKEPLIVKAVER 527          

Query:   92 RPILTVEGSPRLHGHCMHSKVNQVDFVRKQADAFTGCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGI----KPSGRKYSNNQS--------TLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPRE 584
            +P+     SP L  + +  K N     R QA A    K+YG + FG P ++V DP + + I+V+DFDHFVDR GE    + + G    D +W  Q+T L GD+WK+ R TFTP+FT+GK+K M+  I  V   +V  + + +  G+  ++ + F KFSMDT+A CAFGV A+SF+  +  + +  A  +   +     R +   IPG K ++  L I V K    +  ++I+  T+++R +T   RNDLVD+M++AM +   DG     K    +Y  +           +DE  ++A A+V L  GY+TTA T++   Y LAK P  Q++L  EI    R +K    H +Y+ +QS++YLD V+ E LR++  LG+I+R C  DY IP  ++ +K+G EVHI   + H NP  +P+P  +DPERF    + SRH Y FL FG GPR+C+GMRFALLEAK  L ++ R +  +  S T     L+P+A L   ++P+ ++ V RE
Sbjct:   36 QPVFPFGSSPMLGWNSLRQKTNLNADARNQAIALGFPKFYGNYVFGTPNMIVCDPEMAKQIMVKDFDHFVDRQGEDFVKMLSGGHF-VDKVWANQMTALPGDKWKNTRATFTPVFTAGKLKGMIRFIYEVTNDLVKSVGEEAKRGEVFELKEKFGKFSMDTIATCAFGVNAKSFEDDKSTFAMN-ARAVFRNSKSDALRFLTAIIPGGKTILNMLDIPVNKKDITIFFYDIIKGTIEHRIKTKTRRNDLVDLMIDAMKS---DGTVEQDKEQESQYDEDAKLNHKVVPKQIDEITMVATALVILVAGYDTTAQTMAITSYFLAKNPDIQERLYQEIMECVRDLKDENDHPDYNQIQSLSYLDMVLHETLRINPVLGLITRACTKDYVIPDTNITLKKGCEVHINAMAIHANPDIYPDPEKYDPERFTKEAKASRHPYAFLGFGQGPRNCIGMRFALLEAKLGLFAVLRKYKFEATSETVEKFTLDPEAFLSAPKEPLLVKVVERE 535          

Query:    1 MILETLCISLIVLVLLFFAIYLKLTRNNEYWRNRGIPYVPNQFPTGSSPFTDKSVLTGKMQCDNSCCLRPGRPRSDVGGEENLAEGVPRAIRPILTVEGSPRLHGHCMHSKVNQVDFVRKQADAFTGCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQ-FWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPR 583
            M+ E L +   + VL +F +  K T     W  +G+P++P  FP GS+   +  V+ G+                                                     NQ+    +QA +    K +G + FG P+LVV DP + + ++V+DFDHFV+R G+ +A L   G T+ D  W KQIT LRG++WK  R TFTPIFT GK+K M+  I  V  +++  +       QPV++ D F   SMD ++ CAFG+ A SF     N   +   + + RN G+ F++L    +PG   LM  + I V KG E     +I+  T+ +R  T   RNDLVD+M++AM+     G +        +Q + DE  + A A+V L  GY+TTA T++   Y LAK P  Q+KL  EI     +M   + H +Y+ +Q + YLD V+ E LR+   LGVI+RGC  DY  PG D VI +G E+HI V   HMNP  +P+P  FDPERF+   +  RH Y FL FG GPRSC+GMRFALLEAK AL +  R + L  C  T  +  L+P AIL N ++ + ++   R
Sbjct:    1 MLFELLLLIGTLTVLYYFHLKRKWT----LWEKKGVPFIPGTFPFGSTAVFNWDVVLGR--------------------------------------------------KNFNQMAL--EQASSLGFPKVFGVYDFGTPLLVVNDPEIAKQVMVKDFDHFVNRQGDALAFLL-EGKTEVDQAWGKQITSLRGEEWKHSRMTFTPIFTGGKLKGMIHFIHQVTDELIKSLDACVAKDQPVNLKDKFGNMSMDAISSCAFGLNANSFND--KNSTNKRHARRIFRNSGKDFFKLFCAMMPGGVKLMELMNIPVMKGPETEFFLKIIRDTIAHRLLTKTRRNDLVDLMIDAMNENRTKGAR-------EDQDS-DELSIGATALVILVAGYDTTAQTMALTSYYLAKNPDCQEKLYQEIMDAVSEMD--DEHPDYNLVQGLPYLDMVVHETLRIMPALGVITRGCSKDYPFPGIDYVIPKGTELHIYVGGIHMNPDIYPDPEKFDPERFSKEAKAERHPYAFLGFGQGPRSCIGMRFALLEAKLALFATLRKYKLKTCPETVEAFTLDPSAILSNPKEDLLIKLEAR 515          

Query:   11 IVLVLLFFAIYLKLTRNNEYWRNRGIPYVPNQFPTGSSPFTDKSVLTGKMQCDNSCCLRPGRPRSDVGGEENLAEGVPRAIRPILTVEGSPRLHGHCMHSKVNQVDFVRKQADAFTGCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQS--DSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLIL-VRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKPS----GRKYSNNQS---------TLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLR 579
            I +V +F   Y+K  R  +YW +  +P+V   FP GSSP       T   Q  N   L   + R           G P                                        K YGT+ F +P++ + DP L + I+V+DFDHFVDR GE +A    H TT    D LW +Q+T LRGDQWK  R  FTPIFT GK+K M+  I  V   +V  I + +  G P ++ + F +FSMDT+A CAFGV+A SFQ  +  + +  A  +   +P    + +L V +P  +AL+  LG+ + K    + L++I+ QT+ +R  T   RNDLVD+M++AM   P+    P       ++  +            +DE  ++A A+V L  GY+TTA TL+ A + LA+ P  Q+KL  EI      M+  + + +Y+ +QS+ YLD V+ E LR++  LG+ISR C  DY IPG ++ +K GQ+ HI V++ HM P     P  FDPERF    + +RH Y FL FG GPR+C+GMRFALLEAK AL  + R +    C  T  +  L+P +IL   ++P+ ++
Sbjct:    2 IGVVCIFVYYYVKFHRTWKYWEHHNVPFVKPSFPFGSSPTISWETFTSP-QNFNQTALNEAKKR-----------GFP----------------------------------------KVYGTYFFHNPIISICDPELAKHIMVKDFDHFVDRQGEFLAE---HATTSHLVDQLWGRQMTALRGDQWKATRNAFTPIFTGGKLKGMIHFIHEVTHDLVTSIGQEADRGTPFELKEKFGRFSMDTIASCAFGVKANSFQEDKSTFAMN-AGAMFRNSPMDLMKFVLLVAVPRGRALLECLGVPLQKKAPTMFLYDIITQTVDHRLRTKTRRNDLVDLMIDAMKADPQSSNHPEEPVEDSQFDKDAKLNAPDFQPLNVDEMTLVATAMVILVAGYDTTAQTLAIASFHLARNPDIQEKLHQEIMDAVATMEDDKPYPDYNLIQSLPYLDMVLHETLRINPALGLISRTCTKDYIIPGTNIPLKCGQDAHIYVSAIHMEPGHLSGPKKFDPERFTKESKANRHPYSFLGFGQGPRNCIGMRFALLEAKLALFGVLRSYKFVTCPETIDTYTLDPSSILATPKEPLLVK 530          

Query:  104 HGHCMHSKVNQVDFVRKQADAFTGCKYYGTFA-FGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMST----------PPEDGIK---PSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPR 583
            H   +  + N    ++ Q + F    ++G F  FG P +V+ DP L++ IL +DFDHFVDR G+      N+  T +D++W KQ+  LRG+ WKD+R+TF+PIFTSGKMK+M+  +  +  ++  EI K +    P+D+ ++F KFSMDT+A CAFGV++ SF + + + F++ A  +  R     ++L    IPG+  + ++L +S FK  E +  +  +  T+++R+ET   +NDL+D+M++A+            PPED  +    S  ++      +DE +V+A A++ L  GY+ TA T++Y  Y+LAK    Q +L +EID     ++  +   +Y+T+  M+YLD V+QE LR+HTPL V+ R CV +Y+IPG ++VI +G  V +PV + H +  ++P P  F+P+ F       R  Y FL FG GPRSC+GMRFALLEAK  L+++   F    C  TP   +      LGN  + ++++   R
Sbjct:   49 HKKVLLRQKNVAYIIQDQYNQFKNHPFFGVFGPFGSPCIVINDPVLIRAILSKDFDHFVDRFGDLNPFNNNNAETFTDAIWQKQLIFLRGELWKDVRSTFSPIFTSGKMKLMMHFMKAISLKLTDEIRKSADEKVPIDLKEIFGKFSMDTIATCAFGVDSGSFMAKEESDFVKNAKAVFTRTAKDQFKLFCSLIPGLNFICKALKMSFFKPDEAMFFYATISSTIQHRRETKTRKNDLIDMMIDAIEANKKSVGRCEKPPEDTDEFDLDSRLQHKVKNGAIDELVVVATALIILVAGYDATAMTITYCAYQLAKNQDVQDELLAEIDEVMSNLEADQDFPDYTTVMGMSYLDAVLQETLRMHTPLPVLRRVCVKEYKIPGHNVVIPKGSNVTVPVHAIHSDERYYPNPEKFNPKHFAPEAVSQRPPYTFLSFGQGPRSCIGMRFALLEAKVGLIAVLSKFRFQTCPQTPERPQRAKNMFLGNPNETLWVQMAAR 542          

Query:   91 IRPILTVEGSPRLH-GHCMHSKVNQVDFVRKQADAFTGCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRI-PGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPR 583
            ++P+     SP ++    ++   N      +QA A    K++G + F +PV+ + DP + + I+V+DFDHFVDR G+  A  F   +   D LW +Q+  L+G++WK  R TFTPIFT+GK+K M+  I  V + +V  I +     QP D+   + KFSMDT+A CAFGV A+SF+      F + A +     P   W++++  I PG K +M  L I + K  + +  +EIV +T+ +R +T   RNDLVD+M++AM    E    P+ + + N + +LDE  ++A A+V L  GY+TTA TL+   + LA+ P  Q KL  EI     ++   +S+ +Y+ +QS+ Y+D V+ E LR++  LG+I+R C  DY +PG  + +KRG +VHI V++ H N   +P+P  +DPERF+   + +RH Y FL FG GPR+C+GMRFALLEAK AL  + R +    C+ T  S  L P A+L   ++P+ ++   R
Sbjct:   35 VKPVFPFGSSPVMNWSMVLNPTTNFNQGAYEQAKALGFPKFFGLYIFANPVMAICDPEMAKQIMVKDFDHFVDRQGDA-AVEFLRTSHFVDKLWLQQLPSLQGEEWKKSRNTFTPIFTAGKLKGMMQFIHEVTKNLVKSIGQEVALDQPFDLKVKYSKFSMDTIASCAFGVNAKSFEDKNSK-FAKNAREFFRNTPKDMWKVLIAAIVPGGKFVMEKLSIPIQKYEQTMFFYEIVKETVNHRMQTKFRRNDLVDLMIDAMKEDSESDTNPN-QIHDNARKSLDEITLVATALVILIAGYDTTAQTLAITSFYLARNPDIQDKLYQEIVDVSGELD-VDSYPDYNLIQSLPYMDMVLHETLRINPALGLITRACTKDYIVPGTSIPLKRGDDVHIYVSAIHKNREIYPDPDQYDPERFSAQAKANRHPYAFLGFGHGPRACIGMRFALLEAKLALFGVLRSYKFVTCADTVESFTLEPSAMLAAPKEPLLVKVEAR 525          

Query:   92 RPILTVEGSPRLHGHCMHSKVNQVDFVRKQADAFTGCKYYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAM--STPPEDGIKPSGR-------KYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPRE 584
            +P      +P    +    + +  D  + QA A    K+YG + FG P L++ DP + + I+V+DFDHFV+R  E    L   G    D +W  Q+T L+GD+WK+ R TFTPIFT+GK+K M+  +  V   +V  + + +  G+  D+ + F KFSMDT+A CAFGV A+SF+  +  + +  A  +   +     R+I+  +PG K  +   G  + K H  +  ++I+  T+++R +T   RNDLVD+M++AM   TPPE+     G+        +      +DE  ++A A+V L  GY+TTA T++   Y LA+ P  Q+KL  EI     ++K  + H +Y+ +QS+ YLD V+ E LR++  LG+I+R C  DY IPG D+++K+G EVHI   + H NP  +P+P  +DPERF    + +RH Y FL FG GPR+C+GMRFALLEAK  L ++   +     + T     L+P + L   ++ ++++   R+
Sbjct:   36 QPEFPFGSTPMFGWNSFKQEASMNDLAKTQAMALGFPKFYGNYIFGAPNLMICDPEMAKQIMVKDFDHFVNRQAEDFIKLLEGGHF-VDQVWANQMTALQGDKWKNTRATFTPIFTAGKLKGMIKFMHEVTNDLVKSVDQEAKTGKAFDLKEKFGKFSMDTIATCAFGVNAKSFEDDKSTFAMN-ARAVFRNSRWDVLRIIMALLPGGKEFLNFFGSPINKKHVTLFFYDIIRGTIEHRMKTKTRRNDLVDLMIDAMKADTPPEEDKDTEGQFDQDAKLNHKVVSKQMDEITMVATALVILVAGYDTTAQTMAITSYFLARNPDIQEKLYQEIMECVGEIKNEKGHPDYNQIQSLPYLDMVLHETLRINPALGIITRVCSKDYLIPGTDVLLKKGNEVHINAMAIHNNPNIYPDPEKYDPERFTKEAKANRHPYAFLGFGQGPRNCIGMRFALLEAKLGLFAVLWKYKFVATTETVEEFTLDPSSFLSAPKEALFVKVEERQ 535          

Query:  130 YYGTFAFGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGI---------KPSGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPR 583
            YYG +  G   L++ D  L ++ILV+DFD+FVDRNG+    L      ++D +WTKQ+T+  G+ WK+LR+TF+PIFTSGKMK M+  I     +++  I       +  ++ ++  K+SMDT+A CAFGV+A+SF S + + F+Q A  I      +  R +++ +P  K+L+  L + +FK  E    ++ VV +L +R+ET   RNDL+D+ML+A+    +            K +   +   +   DE +++A A+V +  GY+TT TTL+YAC++L+K P  Q++L++EID        ++  ++Y  +Q MTYLDQVI E LR   P+G++ R    DY++PG DLVI++G +V I   S H NP ++P PH F+P+ F    +  R+   FLPFG GPR CLGMRFALLEAK AL ++ R + L     T     L+P A +   +  +Y++A  R
Sbjct:   70 YYGIYFIGGATLIINDADLAKNILVKDFDYFVDRNGDATNKLL-QTKHKTDIIWTKQMTMSTGEYWKNLRSTFSPIFTSGKMKAMMVFIQETSDKLMQAIDAKVTANEDFELKEMLGKYSMDTIASCAFGVDAESF-SNKDSKFVQYASNIFKNTTMEAVRFLIILLPLGKSLLNFLNVPMFKVTETEFFYDAVVASLNHRRETKTRRNDLIDLMLDAIKGEVDVDEHKDDDDQFEKDAKLDHVPRKGEFDELVIVATAIVLMVAGYDTTGTTLAYACHQLSKHPDIQERLRAEIDEVTGD---SDKPIDYDKIQGMTYLDQVISETLRFTCPIGILQRNTTKDYKVPGHDLVIEKGHDVWINAMSIHFNPEYYPNPHEFNPDNFTKEAKGQRNSCAFLPFGQGPRGCLGMRFALLEAKMALANIIRTYNLLPSEKTIEPQELDPYAGIAYVKHGLYVKAEKR 527          

Query:  118 VRKQADAFTGCKYYGTFA-FGDPVLVVTDPCLVQDILVRDFDHFVDRNGETIASLFNHGTTQSDSLWTKQITLLRGDQWKDLRTTFTPIFTSGKMKIMLPLIDHVCQQMVAEITKISYHGQPVDIGDLFEKFSMDTVACCAFGVEAQSFQSGQPNYFLQLAHKILMRNPGQFWRLILVRIPGMKALMRSLGISVFKGHELVLLHEIVVQTLKYRKETHIHRNDLVDIMLEAMSTPPEDGIKP----------SGRKYSNNQSTLDESLVMAAAVVFLFGGYETTATTLSYACYELAKCPQAQKKLQSEIDREHRKMKYTESHLEYSTLQSMTYLDQVIQEALRLHTPLGVISRGCVSDYQIPGDDLVIKRGQEVHIPVASFHMNPAFFPEPHIFDPERFNHNQRQSRHQYLFLPFGVGPRSCLGMRFALLEAKAALVSLFRHFTLDVCSMTPTSLRLNPKAILGNSQDPIYLRAVPR 583
            +  Q   F    YYG +  FG P LV+ DP L++ ILV+D  HF+DR G+ +          +D +W KQ+  L+GD WKD+R+TF+PIF+S K+K M+  +  +  ++  EI K     QP+D  D+F KFSMDT+A CAFGV+A SF+      FLQ A KI + +     +++    PG+  L++SL +  FK  E + ++ ++  T+K+R E+   +NDL+D+M++A++    + I+           S  ++   +  LDE ++++ A++ +  GY+TT+ TL+Y  YELA+ P+ Q+K+  EID     ++  +   +Y+ LQ M YLD VI E LR HTP+ V  R C+ DY  PG DL I++G  + +P+ + H +  ++P+P  F+P+ F    ++SR  Y FL FG GPRSC+GMRFAL+EAK  L S+   +    C  TP ++   P ++LG   + ++L    R
Sbjct:   61 IEDQYSQFKHLSYYGVYGPFGAPTLVINDPNLLKLILVKDSRHFLDRFGD-LNPYGGDSDVFTDKIWQKQLLFLQGDLWKDVRSTFSPIFSSSKIKFMMHFMKAIGIRLKGEIQKAVDSQQPIDTKDVFSKFSMDTIATCAFGVDAGSFEEDNSE-FLQHARKIFINSALDNLKMVASFTPGLNFLLKSLRMKFFKPKETLFMYNVITATIKHRIESQTRKNDLIDLMIDAINETNPENIEDIHSQEQYEIDSNLEHKAQKDKLDELIIVSTALIIMAAGYDTTSMTLTYCAYELAQHPEVQEKVLQEIDEVMVNLEDGQDFPDYNILQGMRYLDAVIHETLRFHTPVPVARRICLQDYTPPGYDLTIEKGTYISVPIYAIHRDAQYYPDPEEFNPDNFTAEGKKSRSPYSFLAFGQGPRSCIGMRFALMEAKVGLFSVLMRYRFSACPQTPKAIIRAPDSVLGIPAETLWLAVQER 535