Query:   79 DGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIEEIFP-------------ILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSVNDK------FTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHG-LTFVEATIMEVQRCSSVAPGGLEHKAL--EDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFI 360
             G+ I++ Q F+    +++       + N       EL++   K+ ++A + +  P             +++Y+  +++G++ +E +   N  +         ++ +   + +DFI+  L EM  N+          E +    + FF AG  T   +L   +  LA +P+IQ+Q  +E+ +         ED+G    ++  A I E  R   + P    H  +   DT +EG  +K GT++   I++      ++ +PE F+PERF  E+ S +   + F PFG G R+C+    A  EL I
Sbjct:  160 SGKSIKIKQKFHGLTLDVINSCAYGIKTNSSQDSDHELLKHAKKLLEDAVVTKNLPTSMFILLLNLFPGMIKYI--DIFGNAYEELIKIANSII--------ANRETENIKKKDFINV-LVEMRKNNNECPNELLNNEIITAQAVIFFVAGYVTTSHSLCCLIYVLATNPEIQDQLYQEILSS--------EDQGFDEHSYTSAVIKEALR---LYPPATMHTRVCTHDTEVEGIFIKNGTIIEMPIYASHYYPEFFPNPEEFKPERFFKENNSEIIP-DTFRPFGDGNRICIAYRFAMMELQI 440          

Query:  125 KNAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSVNDK---FTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQR--CSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAK-------AELFIFTIMILQHLRIKLSPN--HSKPDPNAYEAGI 389
             N  + + FP        L+   V++ L    K +   V  E+K  L+ K   +DF++ Y   +  N +   F  EDL+G        G   V + +   L+++  H DI+++ ++E++    +           +  + A   E  R  CS + P    H++  DT I  Y VK  T+++ N H      S W +P N+ P+RF+D     L     F PF  G+R C+G  L +       A +     + ++++ I L P    +KP P  + + I
Sbjct:  196 NNGRLMDFFP-----WTSLFAGFVQQPLNSHCKFIRSFV--ENKILLNQKFD-DDFLNTY-QRIEKNKELILFALEDLIG--------GHSAVTNVILRILVHILEHGDIKKELQKEIQPFQALTF----KETRNMVLLNACFYETVRLTCSPIIP----HRSKRDTSIGNYCVKNDTVIFINNHFLNYSPSLWYEPLNYNPKRFIDTETGFLSIPAHFQPFSIGRRSCVGYKLTQLICTFSVAHILKTLDLSIKNMEISLPPGMLATKPGPVVFCSKI 449          

Query:  140 GKELYGHSVKEKLTRTNKAVFEAVIKEHKDKL---------SSKEQPEDFIDA-YLTEMSVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTII--EGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGS---GLKKYER----FIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKL 373
             + +YG      +  T    F +++K HKD L          +  Q +DF D   +    V+     +D+    +D+  AG +T+G+T+ + LL LA +P+ Q++ + E++  LG      ++    + +++  + E  R    A      + L++ II   G+ +  G+++  +       +  +   + F PER+L+       G   Y       +PFGFGKR+C G+ LA+ E++I T  ++++  ++L
Sbjct:  269 NESMYGXPWWXYVPETFSGXFTSLVK-HKDYLFGTFGAMIDENLVQNKDFCDEESIIHQLVSGNVDIKDVKASVVDYITAGVDTIGNTVIFALLLLAKYPEKQKKLQAEIERVLGSENYITKENIQEMKYLKGCVNESFRLYPTA--SQIARILDEEIITSNGHSLPPGSVVLCHQRIASLQEQNFTRAKEFIPERWLEXEAVTEFGTTNYAHNKSLVMPFGFGKRICPGKKLAEQEIYIMTAKLMKNFNLRL 518          

Query:  196 KEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKA-LEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHL--RIKLSPNH 377
            K+D + + +   +    T   TL      LA HP+IQE+  +E+       V + +      ++  A I E  R     P  L  +A ++DT +EG  +K GT++   I++   +  ++  P  F+PERF  E+   +     + PFG G R C+    A  EL     +IL+ L  + ++ P H
Sbjct:  256 KKDFLNVLVQMRKKSYSTTSMTLCCLTYILATHPEIQEKLYKEI-------VSSQDKDFSEHSYTSAVIKETLRM--YPPVTLHLRACVKDTEVEGILIKNGTIVEMPIYASHYNPEFFPTPNEFKPERFFQENNLEIIP-NTYRPFGDGNRSCIAYRFAMMEL----QLILEKLVKKFEILPTH 426          

Query:  125 KNAYIEEIFPILQYV--GKELYGHSVKEKLTRTNKAVFEAVIKEHK---DKLSSKEQPEDFIDAYLTEMSVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLD-ESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIK 372
            ++A ++   PI QY+   K LY    + +  R   +  E  +K+ K   +  S +E+  +F+  +L  +      +  +++ L +     G  T    L + L  LA +P  QE+  EE++  +             + F   T  EV R +             D I+ GY V KGT +  N       + ++ DP   +PER+L  +  S +  Y+ ++PF  G R+C+G  LA+ ++ +  + +L+  R +
Sbjct:  320 ESAMLKLSLPIYQYLWTPKSLYLRKKEVEFIRLAYSFVETALKDLKYMTENNSVREK--EFL--FLRFLLGKSDLSLANVITLIISLLTDGLSTTVPVLLFNLYSLAKNPSSQEKLYEEIQRVVKNDSDITTAHLKEILFPSGT--EVSRVTD-----------HDLILSGYEVPKGTRVDLNHGPINKSEEFYEDPLIHKPERWLRGKFPSNIHPYQ-YLPFSHGTRMCIGRRLAEQDMNVVMVTLLRQFRFE 555          

Query:  185 LTEMSVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRI 371
            L+ + ++   + ED+  + MDF  A  +T   +  W L  ++    IQ + R     +L                +   + E  R   V+P  +     +D +IEG  ++ G L+ ++I++   + +Y+  PE+F P+R+ D + S        IPFGF  R C+G+ LA+  +      ++Q  +I
Sbjct:  254 LSGVLISQGVSYEDVERIAMDFVIAAVDTTSISTLWILHLISQDTYIQNEIRISFDNQL----------------LRNCMREASRLYPVSPF-ITRVLDKDILIEGSKLRTGQLILFSIYTMSRNPNYFTKPEHFLPQRW-DITPSSFAS----IPFGFRARSCIGKKLAELSMETLIKGLIQRYKI 418          

Query:  191 NDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHG-LTFVEATIMEVQRCSSVAPGGLEHKAL-EDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAE 357
            N     E +    + FF AG  T  +TL      LA HP+IQE+  +E+ +         ED+     ++  A I E  R     P  L  +   +DT +EG  +KKGT++   I++   +  ++ +P  F+PERF  E+   +     + PFG G R C+    A  E
Sbjct:  292 NTLLNDEIITAQAIIFFIAGYSTTSTTLCCLTYMLATHPEIQEKLYKEIVSS--------EDKDFSEHSYTSAVIKETLRM--YPPVALHLRVCAKDTEVEGIPIKKGTIIEMPIYASHYNPEFFPNPNEFKPERFFQENNLEIIP-NTYRPFGNGNRSCIAYRFAMME 449          

Query:   63 ISEEAGLLMTSLKDKFDG--QDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFK----NAYIEEIFPILQYVGKELYGHSVKEKLTRTNKA--VFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSV-----NDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGV-RVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQL 400
            I EEA  L+ SL  + +G    I +   F+I V N LW ++A  R++ DD  +++L+ ++ K F+    +  +    P L+++     G++    +T  N+        I +H+   ++     D ID +L EM       N  F    LV LC+D F AG ET  +TL + +LY+  +P +Q + ++E+   +G  R PTL+DR   L ++EA +ME+QR +++AP G+ HKAL++T++ G+ + KGT +  ++ S   D  +WGDPE FRPERF+  +G+ +K+ + F+PFG GKR C+GE+LAKA LF+F   +L +  I  S     P    Y+ G+T SP PF  +L
Sbjct:  144 IEEEARDLVASLHRRSNGGLTAIPMHDVFDICVLNSLWAMLAGHRFDLDDQRLVDLLDIVHKCFRMIDPSGGLLNQMPPLRFIAPRHSGYT--NLMTHLNRIWNFLRETIDDHRKSFNADNM-RDLIDLFLREMETSKCQNNSSFEDLQLVSLCLDLFMAGSETTSNTLGFAVLYMLLYPQVQRRVQDELDRCVGTDRQPTLQDR-RSLRYLEAVLMEIQRHATIAPSGIPHKALKNTVLMGHTIPKGTTVLVSMWSLHRDVQHWGDPEVFRPERFISGNGN-IKQDDWFMPFGIGKRRCIGETLAKASLFLFFSTLLHNFSILPSSESPLPSLEGYD-GVTLSPKPFSAKL 489          

Query:    2 NHKFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGYGRPTGGIWN-----------------------------IISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIE----EIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEM--SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGV-RVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLE 401
            + K+  ++G  LG  + VV++   EL ++++  + + GR  G + T MR +G+  G +++                             I  E   L+   L D   G+ I V+Q F+I++ NILWR+VA KRY+ +D  + EL  ++ ++FK   +        P L++    L G +  +++          +IKEH++ L     P+D IDA+L +M  S +DK T +DL  +C+D  EAG ETV +T  + LL++  + D+Q +  +E+   +G  R P L+DR   + + EA I+E  R S+VA  G+ H AL D  +  Y + KGT +  +++   +   +W DPE FRPERFL + G+ L+  E  IPFG GKR C+GE LA++ELF+F   ILQ   +++  N   P     + G++ S   F +  E
Sbjct:   59 SQKYGNLLGLRLGS-INVVVVTGIELIREVSNREVFEGRPDGFFYT-MRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGDECEALVQLRLADA--GEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKELCSLVMRLFKLVDMSGGFLNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQENLQLG-APKDVIDAFLIDMLESQDDKPTLDDLQVVCLDLLEAGMETVTNTAVFMLLHVVRNEDVQRKLHQEIDDIIGRDRNPLLDDRIR-MVYTEAVILETLRISTVASMGIPHMALNDAKLGNYIIPKGTFILLSLYE-LHHGPHWKDPETFRPERFLTKEGNILQD-EWLIPFGIGKRRCIGEGLARSELFMFLTHILQKFHLRIPKNEPLPSTEPID-GLSLSAKQFRIIFE 485          

Query:   92 SVFNILWRIVANKRYNPDDPEILELMQVLAK-----VFKNAYIEEIFPILQYVG----KELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEM------SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGV-RVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQL 400
            +V NI+  +   +R++  + E  +++  +++     +     +  I P L Y+     KEL       ++ +   +  + +IK+H++ L  +E P+DFID YL  M      + N  F +E L  +  D F AG +T  ++L W LLY++ +PD+QE+  EE++  +G  R P+L D+   + + EATIMEVQR + V P  + H   E+T+++GY + KGTL+  N+ S   D + W  PE+F P RFLD+ G  +KK E FIPFG GKRVCMGE LAK ELF+  + ++Q     L  +  KP       G+T +P PF + +
Sbjct:  227 AVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPFGPFKEL------RQIEKDITSFLKKIIKDHQESLD-RENPQDFIDMYLLHMEEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQ-MPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKK-ETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPLLTG-RFGLTLAPHPFNITI 541          

Query:   46 TTTMRGYGRPTGGIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIEEIFPILQYVGKELYGHSVKEKLTRTNK---AVFEAVIKEHKDKLSSKEQPEDFIDAYLTEM-----SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLG-VRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAG-ITRSPAPF 396
             +++R +G     +   ++EEA  L  +  +   GQ        N +V N++  ++  +R++ DDP +L L++ L +  +     +I  +L  +   L    V  K+    +   A+ + ++ EH    +  + P D  DA+LTEM     +    F  E+L  L  D F AG  T   TLSW LL +  HPD+Q   +EE+   +G VR P + D+ H + F  A I EVQR + + P G+ H    DT ++G+ + KGT+L+ N+ S   D++ W  P +F P  FLD  G  +K+ E F+PF  G R+C+GE LA+ ELF+F   +LQ  R   S    +P P+   A  +   P+P+
Sbjct:  139 VSSLRNFGLGKKSLEQWVTEEAACLCAAFTNH-AGQPFCPKALLNKAVCNVISSLIYARRFDYDDPMVLRLLEFLEETLRENSSLKI-QVLNSIPLLLRIPCVAAKVLSAQRSFIALNDKLLAEHNTGWAPDQPPRDLTDAFLTEMHKAQGNSESSFNDENLRLLVSDLFGAGMVTTSVTLSWALLLMILHPDVQRHVQEEIDEVIGQVRCPEMADQAH-MPFTNAVIHEVQRFADIVPMGVPHMTSRDTEVQGFLIPKGTMLFTNLSSVLKDETVWEKPLHFHPGHFLDAEGRFVKR-EAFMPFSAGPRICLGEPLARMELFLFFTSLLQ--RFSFSVPEGQPRPSDRGAPYLVVLPSPY 493          

Query:   90 NISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIEEIF--PILQYVGKELYGHSVKEKLTRTNKAVF-EAVIKEHKDKLSSKEQPEDFIDAYLTEM------SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGV-RVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYV 398
            N +V NI+  +   +R++  + E  +++  +++  +     ++    I  ++    +G   + +    +  +F + +IK+H++ L   E P+DFID YL  +      + N  F ++ L  +  D F AG +T  ++L W LLY++ HP+IQE+  EE+   +G  R P+L D+   + + EATIMEVQR S+V P  + H   E T+++G+ + KGT++  N+ S   D + W  P +F P+RFLD+ G  +KK E FIPFG GKRVCMGE LAK ELF+  + ++Q     L P  SKP     + G+T +P PF +
Sbjct:  225 NNAVSNIICSLCFGRRFDYTNSEFKQMLNFMSRALEVCLNTQLLLVNICSWLYYLPFGPFKELRQIEKDLTLFLKKIIKDHRESLDV-ENPQDFIDMYLLHVEEEKKNNSNSGFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLHPNIQEKIHEEIARVIGADRAPSLTDKAQ-MPYTEATIMEVQRLSTVVPLSIPHMTSEKTVLQGFTIPKGTIILPNLWSVHRDPAIWEKPNDFYPDRFLDDQGQLIKK-ETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFVL-PKDSKPILTG-KYGLTLAPHPFNI 538          

Query:   92 SVFNILWRIVANKRYNPDDPEILELMQVLAK-----VFKNAYIEEIFPILQYVG----KELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEM------SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGV-RVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQL 400
            +V NI+  +   +R++  + E  +++  +++     +    ++  I P   Y+     KEL       ++ R      + +I+EH++ L +   P+DFID YL  M      S    F ++ L  +  D F AG +T  ++L W LLY++ +PD+Q++  EE++  +G  R P+L D+   + + EATIMEVQR S V P  + H   E T+++G+ + KGT++  N+ S   D + W  P++F P RFLD+ G  LK+ E FIPFG GKRVCMGE LAK ELF+  + ++Q     L     KP       G+T +P PF V +
Sbjct:  213 AVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINICPWFYYLPFGPFKEL------RQIERDISCFLKNIIREHQESLDAS-NPQDFIDMYLLHMEEEQGASRRSSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQKKVHEEIERVIGCDRAPSLTDKAQ-MPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGFTIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLKR-ETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQTFTFALPEGSEKPVMTG-RFGLTLAPHPFNVTI 527          

Query:   46 TTTMRGYGRPTGGIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFK--NAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVF---EAVIKEHKDKLSSKEQPEDFIDAYLTEM-----SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLG-VRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPF 396
             +T+R  G     +   ++EEA  L  +  +   G+  R +   + +V N++  +   +R+  DDP  L L+ +  +  K  + ++ E+   L  V   L+  ++  K+ R  KA     + ++ EH+      + P D  +A+L EM     +    F  E+L  +  D F AG  T  +TL+W LL +  HPD+Q + ++E+   +G VR P + D+ H + +  A I EVQR   + P G+ H    D  ++G+ + KGT L  N+ S   D++ W  P  F PE FLD  G  +K  E F+PF  G+R C+GE LA+ ELF+F   +LQH    +     +P  +   A +  SP+P+
Sbjct:  136 VSTLRNLGLGKKSLEQWVTEEAACLCAAFANH-SGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREV---LNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAH-MPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKP-EAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLV-SPSPY 490          

Query:   31 IAYSDTYSGRLIGMYT-TTMRGYGRPTGGIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNIS--VFNILWRIVANKRYNPDDPEILELMQVLAKV--FKNAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSS--KEQPEDFIDAYLTEMS----VNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGV-RVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITR 391
            +A+S+    + +  ++  T+R +G    G+   I EEAG L+  L+         +D T  +S    N++  IV   R+N +D E L L+Q++ +V  F  +   +++ +   V K L G   ++++ + +  + + +I++ K   S+     P DFID++L  M     VN +F  ++LV   ++ F AG ETV STL +  L L  HPD++ +  EE+   +G  R P  ED    + + +A I E+QR S+ AP G+  +  +DT   G+ + KGT ++  + S   D  ++  P++F P+ FLD+ G  LKK   F+PF  GKR C+G+SLAK ELF+F   ILQ+ R K        + +    G TR
Sbjct:  115 VAFSNGERAKQLRRFSIATLRDFGMGKRGVEERIQEEAGCLIKMLQGTCGAP---IDPTIYLSKTASNVISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMKYLPGP--QQQIIKDSHKLEDFMIQKVKQNQSTLDPNSPRDFIDSFLIHMQKEKYVNSEFHMKNLVMTSLNLFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDH-MKMPYTQAVINEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLDDKGQ-LKKIPAFLPFSTGKRFCLGDSLAKMELFLFFTTILQNFRFKFPRKLEDINESPTPEGFTR 480          

Query:   47 TTMRGYGRPTGGIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFK--NAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAV---IKEHKDKLSSKEQPEDFIDAYLTEM-----SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGV-RVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSP 393
             TM+ +G     +   I EEA  L+  LK K+ G  +     F     NI+  IV  +R++  D + L L+ ++ K+F   +++  ++F +  + G   Y   V  ++ +  + + + +   +++HK  L     P D+ID YL  M     + N +F  ++L+   +  F AG ET  +TL + +L +  +P + E+ ++E+   +G  R+PTL+DR   + + +A I E+QR S + P GL HK ++DT+  GY + K T +Y  + S  +D  Y+  P+ F PE FLD +G+ LKK E F+PF  GKR+C+GES+A+ ELFIF   ILQ+  +         D    E+GI + P
Sbjct:  130 ATMKEFGMGKRSVEERIKEEAQCLVEELK-KYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFEL--FSGFLKYFPGVHRQIVKKQQELLDYIAHSVEKHKATLDPSA-PRDYIDTYLLRMEKEKSNHNTEFHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRT-KMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFLDANGA-LKKCEAFLPFSTGKRICLGESIARNELFIFFTTILQNFSVASPVAPKDIDLTPKESGIGKIP 481          

Query:   44 MYTTTMRGYGRPTGGIWNIISEEAGLLMTSLKDKFD-----GQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQ----VLAKVFKNAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDF-------IDAYLTEMSVNDK-FTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGV-RVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGL-KKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLE 401
            +  + +  +G  + GI  +I +EA    TS+   F+       D+  D T   +V N++  +  N  Y  +DPE   + +    ++  V K++ I+ IFP LQ+   E   H++K+ +  T  ++ +   ++HK   SS    + F       ++A     SV++   T + +V    D F AG ET  +  +W ++YL +HP++Q++ +EE+ + +G  R P + D+G+ + F+ ATI E+ R   V+P  + H AL D+ I  Y + KGT +  N+ +  +D+  W +P+ F P RFLDE G  +    E ++PFG G RVC+GE LA+ ELF+FT  ILQ   +++ P +  PD    + GI   P  F VQL+
Sbjct:  132 LVLSALHLFGDGSAGIEKMICQEA----TSMCSTFERLNNAAHDMMPDVTR--AVTNVICLLCFNSTYEKEDPEFQTMRKYSQGIVNTVAKDSLID-IFPWLQFFPNENL-HTLKQCIA-TRDSILQKKFEDHKANYSSDSANDLFNILLKAKMNAENNNSSVHEAGLTDDHMVMTVADIFGAGVETSSTAFAWMIIYLIHHPEVQKKIQEEIDSNIGFERTPKMSDKGN-MNFLNATIHEILRIQPVSPLLIPHVALADSSIGDYTIPKGTRVIINLWAIHHDEKEWKNPDAFDPGRFLDEDGKYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQVPPGYPPPDKEG-KFGIVLQPLKFKVQLK 497          

Query:    1 MNHKFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGYGRPTG----------------------------GIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLEAL 403
            MNHKFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGYGRPTG                            GIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLEAL
Sbjct:   55 MNHKFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGYGRPTGVICTEGHNWRTNRRFALSTLKEFGFGNKGIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLEAL 485          

Query:    4 KFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGYGRPTG----------------------------GIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIEEIFPILQYV--GKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLEAL 403
            ++ KM+G+F G  MRVVII+DF+LAKK+A+SDT+SGRLIGMYT TMRGY R  G                            G+W+II+EEA +++T LK K+DGQD  V+QTFNISV NILW+IV+ KRY+PDDPE+ ELM+VLA VFK+AYIEE+FPILQY    +E YGHS K+ LT+T K++FE VI+EH+ KL +KE P DFID YL     ND FTKEDL+G+CMDFFEAGGETVGSTLSW LLY+A HP++Q++CR+E+   LGVR PT+ DRG  + + EATIME+QRCSSVAP GLEHKALEDT ++GY +KK TLL+YNI+SFF D+ YWGDPENFRPERFL++ GS   KYERFIPFGFGKRVCMGESLAKAELFIFTIMILQ+LRIK+S NH+KPDP  YEAGITRSP PF+V LEA+
Sbjct:   58 QYPKMVGFFAG-RMRVVIINDFDLAKKVAFSDTFSGRLIGMYTETMRGYNRNIGVISTQGQIWRHNRRFSLSTLKEFGFGNKGMWSIIAEEAAIIVTDLKTKWDGQDFVVNQTFNISVLNILWKIVSGKRYHPDDPEMKELMRVLALVFKSAYIEEVFPILQYTKFTQEWYGHSQKQLLTQTFKSMFEQVIREHEQKLHTKESPRDFIDVYLEAKKGNDLFTKEDLIGICMDFFEAGGETVGSTLSWVLLYMALHPEVQKKCRQEIFNCLGVREPTMNDRG-TVPYTEATIMEIQRCSSVAPSGLEHKALEDTELDGYTIKKDTLLFYNINSFFLDRDYWGDPENFRPERFLNDDGSKTLKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQNLRIKISANHAKPDPGQYEAGITRSPLPFHVTLEAI 485          

Query:    3 HKFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGYGRPTGGIWN----IISEEAGLLMTSLKDKFDGQ-----------DIRVDQ---------TFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIE-EIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSVNDK----FTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLG-VRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQL 400
            +K+  MM +F+G     VII+DF+LAK +   D +SGRL   +   +RG      GI N    + +E+    +  L+D   G+           D+ +DQ         TFN  + N+LW+IVA+KR++P +P   +LM +L   FK+       FP+L   GK L  +++ + L    K +   +I EH   +   + P DFID YL E+  N K    F  E L+ +C+DFF+AG ET  +TL W ++ +A +P +Q++C++E+   LG  R+PT++D    L +V AT+ME+QR S VAPG L H  ++D  +  Y  KKGT+   N+  F ND   + +PE F  ERFL++    LKKYE F+PFG GKR+CMGESLAK ELFIF +  LQ L  K++    KP+P  Y AGITR P P+YV +
Sbjct:   56 YKYGPMMSFFVGSSTVFVIINDFQLAKDLFLRDEFSGRLKTWWHQNVRGNQGRNLGIINTDGTVWTEQRRFALKQLRDLGFGRKSLDSIMIEEVDVLIDQLDGLTSMDSTFNTPIINVLWQIVASKRFDPQEPRTKKLMGLLNMQFKHGLNRLAFFPLL---GKILPYNAIDKSLFEL-KQMMRQLIHEHMHSIDL-DNPRDFIDVYLKEIQSNPKPSHNFDIEQLIVICLDFFQAGAETTSTTLLWAVMLMALYPKVQQKCQKEIDEILGGSRLPTIDDMPK-LVYVMATLMEIQRFSKVAPGSLPHMLIQDVQVMQYKFKKGTIFISNLTKFLNDPIIFPNPEEFIVERFLED--GKLKKYEEFVPFGIGKRICMGESLAKNELFIFFVRTLQRLNFKVAEG-LKPNPQKYTAGITRIPDPYYVHI 474          

Query:    4 KFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGYG-------RPTGGIW----------------------NIISEEAGLLMTSL-KDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYI-EEIFPIL-QYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSV-----NDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLE 401
            K+ K+    LG  +R  +I+DF  AK +   D  S R +      ++G+          +G  W                      ++I EEA LL+ SL ++ +   DI +  TFN  V N+LW++VA+ R++P+  +  ++M+ L + FK        FP L +Y+    +   + +      KA+    +  H+        P DF+D Y++E+S      +  F +E LV +C DFF+AG ET  +TL+W +LY+A +P++Q +C  E++  +G   PTL+D    L +  AT+MEVQR S  APG L H   ED  +EG+ + K +++  N  SF  D+  W +PE F P+RF+  +G  + K E+F+PFG G R+CMGESLAK+E+FIF +M+LQHL+I  S  +  P+P     GIT  P PF+V +E
Sbjct:   59 KYGKIARVDLG-RLRFFVINDFGTAKDLFNRDITSNRPVSWLHKYLKGFNGKICGIIHASGATWREQRRFALKNLRDFGFGRKSLDHVIHEEAQLLIKSLLEEHWTHGDILIGTTFNAPVVNVLWQVVASTRFDPNAQKTKDMMEKLTERFKAGLTWSSAFPFLNRYLPLSKFNQDLLD-----FKAMIRKEVIAHEQDHDPDLPPRDFMDVYISEISSQTHPESSNFHREQLVTICTDFFQAGSETSSTTLAWCVLYMALNPEVQSRCSSEIQDTIGATNPTLDDINR-LVYTRATVMEVQRISVTAPGSLLHITSEDIHMEGFVIPKKSIMIANQKSFLMDECVWPNPEAFMPDRFIGANGK-IVKPEQFVPFGIGPRICMGESLAKSEIFIFFVMLLQHLQISSSKTYGPPNPKNLTTGITTIPDPFHVHIE 485          

Query:   17 MRVVIIHDFELAKKIAYSDT---------------YSGRLIGMYTTT--------------MRGYGRPTGGIWNIISEEAGLLMTSL--KDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFK-NAYIEEIFPILQ-YVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEM-----SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQL 400
            +R  +I+DF +AK +   DT               Y G+++G+  T+              +R +G    G+ ++I +EA  L+ SL  + +    ++ +  TFN  + N+LW+IVA+ R+ P +   +E+M+ L++ FK    + +  P L+ Y+       SV E      K +    ++ H+          DFID YLTE+     S +  F KE LV +C+DFF+AG ET  +TL+W ++++A +PD+QE+C +E+K  +G   P L D    L +V AT++EVQR S+ AP  L H   ED  ++ + + K +LL  N+  F ND+  + +PE F P RFLD SG  + K E F+PFG G+R+CMG+SLAK+E+FIF +MILQ ++I +S     PDP+ Y  GIT  P PF+V +
Sbjct:   68 LRFHVINDFSVAKDLFNRDTTAHRPVNWYLKEVKGYRGQVLGIIGTSGPLWTEQRRFALKNLRDFGFGRKGLDHVIQDEASQLVQSLLSESRNFSHEVLISNTFNAPIINVLWQIVASNRFEPGEKSTIEMMEKLSEQFKARMKVIDFIPFLRPYLPLPKTSRSVLE-----FKDMIRKEVENHEVDHDPNIPARDFIDVYLTEIKRSKESGDANFHKEQLVTVCLDFFQAGAETSSTTLTWFVMFMALNPDVQERCFQEIKQIIGNAPPRL-DHMKELNYVHATMLEVQRMSATAPTSLIHATTEDIKVDDFIIPKKSLLMANLKLFLNDQKAFPNPELFNPSRFLD-SGGLITKPEEFVPFGLGRRICMGDSLAKSEIFIFMVMILQKIKISVSKQDGPPDPSKYTIGITSIPDPFHVAM 482          

Query:    1 MNHKFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGR---LIGMYTT------------------------TMRGYGRPTGGIWNIISEEA---GLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAYIEEIF--PILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLEA 402
            +N    K++G +LG +  +V I+DFE+AK+I   D  +GR   ++  + T                        T+R +G     + +++ EEA   G    S KD    +   V   FN+ + N+LW IVA KRY   DP+   +++++ +  +   +  +F  P ++Y+  +  G + ++K+    + +   ++ EHK    + +   DF+D YL EM    +F +E L+   MD F AG ET  +TLSW +LY+  +PD+Q +  +E+   LG R PTLEDR   L + +A IME+QR  S+AP  + H+AL+D  ++GY + K TL++  ++    D  YW DP  F+PERFL   GS + K ERFIPFG GKR C+GESLAKAELFI    +LQ      +P H  P       G   +P PF+   +A
Sbjct:   56 INRYHSKIVGLYLGRF-PIVAIYDFEVAKEIFSRDDLTGRPDNVLYRFRTNGKNQGLMFADGNSWKSHRRFSLKTLRDFGFGKSSLESVLIEEADRMGEFFLSQKD----EPFLVQTLFNLVILNVLWTIVAGKRYELSDPKAQGIVRLITESVQVENLRFLFNMPWVRYLFPQASGWNTQKKIIGDLRDLVGGLVDEHKSNFDTSDM-RDFMDVYLREMDGRTEFNEEALIVTAMDLFAAGSETTATTLSWAVLYMILYPDVQAKVYKEISEVLGDREPTLEDRS-SLPYTDACIMEIQRLGSIAPMAVPHRALKDVEVKGYRIPKDTLVFSVLYHILRDPDYWPDPNAFKPERFLTPDGSQVIKEERFIPFGVGKRYCLGESLAKAELFIILTRLLQKFSFHSAPGHPVPSDQPV-FGFIYAPKPFHAVTKA 481          

Query:   17 MRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGY-------GRPTGGIWN----------------------IISEEAGLLMTSL-KDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAY-IEEIFPILQ-YVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEM-----SVNDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLGVRVPTLEDRGH--GLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQLE 401
            +R+ +I+ FE+AK +   D  S R    Y   ++G+          +G  W                       II EEA +L+ SL K+  + +++ +  TFN  + N LW+IVA+ R++P+D    ++M+ LA  FK+   I +  P+++ Y+       ++ E      K +    I  H+        P DFID YLTE+     S +  F +E LV +C+DFF AG ET  +TL+W+++ +A +P+IQE C EE++  +G + PT    GH   LT+  AT++EVQR S+  P  L HK  ED  ++GY + K +L+  N+  F +D+  + +P+ F P RFLD++G  + K ++F+PF  G+RVCMGESLAK+ELFIF    LQ  +I  + +    +   +  G+T  P PFYV +E
Sbjct:   68 LRLYVINGFEVAKDLFNKDNTSHRPTTWYQKEIKGFHGQVLGINEASGQTWIEQRRFALKNLRDFGFGRKSMDLIIQEEADMLIQSLLKENREKKEVLIVNTFNAPIVNALWQIVASNRFDPEDEATKDIMEKLALHFKSRMEIIDFVPVIRPYLPVSKSSQAILEL-----KEIIRKEILAHEQDFDPNAPPRDFIDVYLTEIKRAEGSSDSNFHREQLVTVCLDFFLAGAETTSTTLTWSVMLMALYPEIQENCYEEIQKLIGSQPPT---TGHMKDLTYCHATMLEVQRISATVPASLPHKTTEDIQMDGYVIPKDSLMIANLRLFLHDEKVFPNPKEFNPSRFLDDNGM-ITKPDQFVPFSLGRRVCMGESLAKSELFIFFASFLQKSKITANKSREPLNLENHTVGMTCIPDPFYVIVE 482          

Query:   51 GYGRPTGGIWNIISEEAGLLMTSLKDKFDGQDIRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFKNAY----IEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSV-----NDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLG-VRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQ 399
            G+G+ +     +I EE   LM  +K+    + ++V   FNI   N+LW ++A  RY  DD +   L+  L   F++      +  IFP+L+ +  EL GH  K +        F   I EHK  L  +  P DF+D YL +M       N  FT+E L+ LC+D F AG E++ + LS+ LLY+  HP +QE  ++EV   +G  R P+LEDR   L +VEATI E+ R + +AP  L H +L DT + GY +K+ T +  NI S  +D+ +W DPE FRPERFLD  G  +K  ER IPFG GKRVC+GE LAK  LF+    ++Q    +       P  +A    IT +PAPF VQ
Sbjct:  133 GFGKKSAEA--VILEETEQLMIEMKEM---KVVQVSGLFNIPSVNVLWSMIAGTRYAHDDADFKLLLHKLNSFFRSGSPAGNLATIFPVLKKIAPELCGHKKKMEALNELTNFFRKTIHEHKLMLE-ENNPRDFMDVYLQQMEAEKADDNSTFTEEGLIVLCLDLFSAGAESLSNALSFCLLYMVLHPRVQEAVQKEVDTVIGRSRRPSLEDRTR-LPYVEATISEISRINPIAPITLPHTSLRDTELCGYTIKENTTILVNIWSVLHDREHWSDPEVFRPERFLDADGKFVKD-ERLIPFGVGKRVCLGEILAKDMLFLMFTNLMQEFTFRTPEEDPYPTTDALPGFIT-APAPFRVQ 482          

Query:    1 MNHKFKKMMGYFLGPYMRVVIIHDFELAKKIAYSDTYSGRLIGMYTTTMRGYGR------PTGGIW----------------------NIISEEAGLLMTSLKDKFDGQD--IRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFK----NAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSV-----NDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLG-VRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQL 400
            ++ KF  ++G  LG   RVV++  ++ A+ I  SD + GR  G +   +R +G+        G +W                        I+ EAG L+T L+DK +G    +++   F++ V N LW ++A +R+  DD  ++EL+ ++   F+       +    P L+++     G++    +           I EH+  LS      DFID+YL EM V     +  F    LV LC+D F AG ET  STL + +LY+ +HP++Q +  +E+   +G    PTL+ R   L +VE+ IMEVQR +++AP G+ H+AL+DT + G+ V +G  +  +I S   D+ +WGDPE FRPERFLD  G G+     F+PFGFGKR C+GE L K+ LF+F   +L +  I + P H  P     + G+  SP PFY  L
Sbjct:   58 LHAKFGPVVGARLG-RTRVVVVSGYKAARHILLSDEFEGRPDGFFFR-LRTFGKQLGVVFAEGHLWYEQRRFCLQHLRKLGMGKHSMQAQIAAEAGDLVTRLRDKSNGGSTPLKLHDAFDVCVLNSLWAMLAGERFALDDRRMMELIDIVHVSFRVIDTCGGLLNQMPFLRFIAPGWSGYTRLLSVLNRLWGFLRETIDEHRKTLSPGCT-RDFIDSYLEEMEVRKNETDSTFNDMQLVSLCLDLFMAGSETTSSTLGFAVLYMLHHPEVQRRVHDELDGVVGRSNQPTLQHRPR-LCYVESVIMEVQRHANIAPLGIAHRALKDTRVMGHFVPEGATVIVSIWSVHMDRKHWGDPEVFRPERFLDGKG-GIVHDNWFMPFGFGKRRCLGEILGKSGLFLFFSTLLHNFSISVPPGHRLPSLEGSD-GLALSPRPFYASL 491          

Query:   63 ISEEAGLLMTSLKDKFDGQD--IRVDQTFNISVFNILWRIVANKRYNPDDPEILELMQVLAKVFK----NAYIEEIFPILQYVGKELYGHSVKEKLTRTNKAVFEAVIKEHKDKLSSKEQPEDFIDAYLTEMSV-----NDKFTKEDLVGLCMDFFEAGGETVGSTLSWTLLYLANHPDIQEQCREEVKARLG-VRVPTLEDRGHGLTFVEATIMEVQRCSSVAPGGLEHKALEDTIIEGYHVKKGTLLYYNIHSFFNDKSYWGDPENFRPERFLDESGSGLKKYERFIPFGFGKRVCMGESLAKAELFIFTIMILQHLRIKLSPNHSKPDPNAYEAGITRSPAPFYVQL 400
            I+ EAG L+T L+DK +G    +++   F++ V N LW ++A +R+  DD  ++EL+ ++   F+       +    P L+++     G++    +           I EH+  LS      DFID+YL EM V     +  F    LV LC+D F AG ET  STL + +LY+ +HP++Q +  +E+   +G    PTL+ R   L +VE+ IMEVQR +++AP G+ H+AL+DT + G+ V +G  +  +I S   D+ +WGDPE FRPERFLD  G G+     F+PFGFGKR C+GE L K+ LF+F   +L +  I + P H  P     + G+  SP PFY  L
Sbjct:   10 IAAEAGDLVTRLRDKSNGGSTPLKLHDAFDVCVLNSLWAMLAGERFALDDRRMMELIDIVHVSFRVIDTCGGLLNQMPFLRFIAPGWSGYTRLLSVLNRLWGFLRETIDEHRKTLSPGCT-RDFIDSYLEEMEVRKNETDSTFNDMQLVSLCLDLFMAGSETTSSTLGFAVLYMLHHPEVQRRVHDELDGVVGRSNQPTLQHRPR-LCYVESVIMEVQRHANIAPLGIAHRALKDTRVMGHFVPEGATVIVSIWSVHMDRKHWGDPEVFRPERFLDGKG-GIVHDNWFMPFGFGKRRCLGEILGKSGLFLFFSTLLHNFSISVPPGHRLPSLEGSD-GLALSPRPFYASL 355