multidrug resistance-associated protein 1 isoform x3, snap_masked-scaffold3214_size9680-processed-gene-0.0 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000002221 (supercontig:LSalAtl2s:LSalAtl2s1420:21426:31801:1 gene:EMLSAG00000002221 transcript:EMLSAT00000002221 description:"maker-LSalAtl2s1420-augustus-gene-0.12") HSP 1 Score: 1147.88 bits (2968), Expect = 0.000e+0 Identity = 654/1559 (41.95%), Postives = 927/1559 (59.46%), Query Frame = 0
Query: 176 FC--RDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSP--IWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLALED----------KASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQVK--------------DKLVDFTTT--IRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTL---DDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTS-------------------------DPMSSDKDPDEPKV-------MLPDVIAETPDQQESTLVVEL------EKTSNGTK--------ADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWAD-------------------YNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
FC RDPF+D + WNT DPN T C R T+LV IPC F P I+ +Y + A+ T+ K + F L L+ FV+L W + E L+ I + L VF++L V+ ISP L F+L L I+ +M T + F +F ++V F+ +V+ RP + A+ D +S S + FSW+D LLW GF+R L++ L S++ F+ + + ++ D V+ T +P +S+ P L + G +L + VI I L FV P ILK +I ++E W+G Y IL ASSTV ++ + + V +++++SL+ +YRK+L++ +K + GE+ NLMSVDAQ+IVD P + ++ ++P I IA+Y L+ LG + L+G+ V +LIP N F + + LQ Q++ KD+R+KLLNEV+ G+K++KLYAWE F+ IS++R E+K++ L A +F ++ P LV++V F ++ P +VL +EK F L+LFN++R PL M P + V VS KRINKF+N+ EID + V DD K AI L A L W+ D K +L ++L I GSL A+VGTVG+GKSSLL++ LGEM+K+SG + VRGSIAY QQAW+ N +LK+NILF++ Y +Y ++V C L+SDL +L D TEIGE GIN SGGQKQRVSLARAVYS +DIYLLDDPLSAVD+HVGK I+ V+ S+ G LKDKTRV+VTH + +L D IIV+K+G+V+E G+Y++LL AF+EF++Q+ S + ++ K + ++ ++ P S L E T N TK ++E G VKW +YM+YV+++ +L V + + + +++ L+ W+D NQD D YYL IY G L I+ ++ ++ C +A+Q +H ++L+ I++SPMSFFDT P GRI+NR D+D +D +P L + CF ++ ++++ +TP F + I Y+ IQR ++ TSRQ+KRLES S+SPI + FSETV+G A+IRAY Q F+ ES+++V F +NRWL R+EV+GNL+VF AA+ AVL R+SLSPG+ GLS++Y+L + +LNW++RM E+ETN VA+ERI EYT EA W + D K WP +G +SF++Y+TRYR+GLD VLK + +++ EKIGI GRTGAGKSS TLS+FRIIE V G I+IDG DI++LGLH LRSRITIIPQDPVLF+G+LR NLDP + Y++ I A+ H+HLK I LK GL++ ++EGGEN S+GQRQLICLARALLR+T++L+LDEATAAVDL TD+LIQ TIR EF+ TVITIAHRLNTI+D +I V +G+ E+G+ AELLAD S +M +DAG
Sbjct: 20 FCSDRDPFWDPDYAWNTNDPNFTSCFRKTILVWIPCLFFWAFLPFHIYKLYHSKARKVPLKTLGRVKALSCFIL----ILIAFVDL--GYWGSKEFYP--KDLINPIIRAITFLAVFILLF-----VERARGYRISPLLTSFFLIYFATNTIDLYGHIRWVMMSGTTXLADITFFLHFFCIIVSFLCHFFVEPRPL-YEDTAVNDIKSNNPCPLITSSFPSQISFSWLDSLLWTGFKRNLSFDDLWDLVPSLSSRTVVPIFLQRLDSALRRVKTNENGITYAKGDDNVEVKTKHEKKPQLSILPALARTFGPSILSAAVIKIVSDSLNFVPPLILKRIIKFSTNQEELWKGILYAVILFASSTVGSLVLSKFFYKMYVVGMKIKTSLISTIYRKALRVPTSTKKNISTGEIVNLMSVDAQKIVDLMPYINTVWSAPFQITIAIYLLWQTLGPSVLAGVLVMILLIPFNGFIASRTKTLQTNQMKEKDERIKLLNEVVQGIKIVKLYAWEQSFLDIISNVRSKEVKILTHIGYLQAGNSFIWTCAPFLVSLVTFATFILSSPENVLDSEKAFVCLTLFNILRFPLSMLPMIIGSMVLAGVSIKRINKFMNSEEIDEEAVEKKTAYPDD--KFAINLEKACLKWESDEDKNILSDVSLDIEVGSLVAVVGTVGSGKSSLLSAILGEMDKVSGLITVRGSIAYGAQQAWVLNTSLKNNILFNKSYDGDKYTRIVEACALKSDLDMLPGGDETEIGEKGINLSGGQKQRVSLARAVYSGSDIYLLDDPLSAVDSHVGKHIYDNVISSSSGILKDKTRVMVTHGVTYLPFTDKIIVMKDGRVSEIGTYKELLRQKGAFAEFIVQFLSEANENEVNENIKHDIEESFGKNELLEQITKAKQIVRERSVSLNSGDLVTSLVKNNPTNSASGSTTSLKENSGDESTDNDTKQTRPTTSQTQQYQDEKVETGSVKWNIYMHYVKNMSIILVVACSSCFVIYQALNTLSNVLLAWWSDAVMKIEVRTGLNDNRTLDEINQDIMDXQV----YYLSIYGGYCLGQGIVVVMGFVFMYLACMEAAQRLHNQMLESILKSPMSFFDTTPQGRILNRLGKDLDVLDSVMPMVLRGWISCFLGVLSSLIVVMVTTPVFIIPASLIIICYFFIQRIYVATSRQLKRLESSSRSPIXSFFSETVSGAATIRAYGQSSTFISESESKVDDNQKANFPATVSNRWLAVRLEVVGNLIVFTAALLAVLGRDSLSPGLVGLSVSYALAVTASLNWLVRMASEVETNIVAVERIQEYTKAEKEAPWIIE-DTKPDEDWPRKGEISFKNYSTRYREGLDYVLKNVSLDIEGGEKIGIVGRTGAGKSSFTLSMFRIIEPVTGNIIIDGVDITKLGLHQLRSRITIIPQDPVLFSGSLRRNLDPLDEYNETNIMEAISHSHLKPFIDSLKDGLEYHVSEGGENLSLGQRQLICLARALLRRTRVLILDEATAAVDLETDNLIQKTIRSEFKDSTVITIAHRLNTIMDYSKILVLKNGERVEYGTVAELLADKKSQFYSMCSDAG 1557
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000008248 (supercontig:LSalAtl2s:LSalAtl2s498:229862:245360:1 gene:EMLSAG00000008248 transcript:EMLSAT00000008248 description:"maker-LSalAtl2s498-snap-gene-2.25") HSP 1 Score: 1050.43 bits (2715), Expect = 0.000e+0 Identity = 619/1544 (40.09%), Postives = 914/1544 (59.20%), Query Frame = 0
Query: 159 EIRWEEYLLRMSTSEDPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSP--IWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISP-PLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEWVLFLT---YFPIVLVLFITQCWVD------------IRPSSAKHLALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQVKDKLVDFTTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHV-NSKEPTWQGFFYTGILLASSTVSTITFHVYQQL---LSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLL-ADGKAFSEFLIQYTSDPMSSD-KDPDEPKVMLPDVIA------------ETPDQQESTLVVEL----------------------------EKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDL-ATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVP-EAEWDLP-LDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDA 1635
E+ E ++ ST FC DP ++ N TW T DP T C T+LV +P + +P IW + N +N + T F I + +I ++L+ ++ S +V I+ + L VF++ L +K +S PLF+FWL + + + +++ V T + V T +P+V++L W D + PSS + AS S L FSW D ++ +++ +T L + +N + + W +++ ++ +P LWP LV++ LL S + F+ + F PQ++ L+IN V + KEP W+G+ Y L A +++ I +Y Q ++ +++R+SL +++ K++ L + ++KQ +VGE TNLM++D+QR++D + + +SP I+IA+Y L+ LG A L+GLAV +LIP+N+ K ++ Q++ KDKR+KL++++LNG+KVLKLYAWE F+ +++ R EI ++ A + A+ +F ++S P LV + F YV ID ++LT F SL+LFNL+R+PL + P +++ ++ VS RIN FLN ++D ++H + +A+++ N +L+W+ D G L+ I+L I +GSL AIVG VG+GKSSLL+ LGEME + G + V G Y PQQ W+QN TL++NILF + ++ Y +V+ C L DL +L D TEIGE GIN SGGQK RVSLAR ++ DIY+LDDPLSAVD HVG+ +F V+ S G LK+KTR+ VTH FL + D IIV+KNG ++ESG+Y+ L+ + F++FLI Y D + K+ + K ++ D+ + E +ST + +L E SN LIEEE G +K +Y+NY + G L F + Y G A+ LS W+ D + +T+ +YL IYA +G I ++ + AS IH KLL+ ++R+P+SFFDTNP+GRI+NRFS DID +PF + + F+ + IVIIC + P F +I P I Y +IQ+F+I+ +RQ+KR+ES+S+SPI++HF+ET+TG+ +IRA+ F+ E+ ++ A C F V ++RWL R+E LGN++V F A+F++ SR + PGM GLS++Y+L++ LN +I + ++ETN V++ERI EY N+P EA +DLP DP WP G + F++Y TRYR GLDLVLKGI+ ++ EKIGI GRTGAGKSSLTL+LFRIIE +G I IDG++I LGL LRSRITIIPQDP+LF+G+LR NLDP E ++D +IW ALE++HLK + L GL+ + EGG N SVGQRQLICLARA+LRKT+ILVLDEATAA+DL TDDLIQ+TIR EF+ TV+TIAHR+NTI+D +RI V G IAEF P LLA+P S ++VND+
Sbjct: 13 ELNLESTVMGTST----FCSDPLWNSNLTWYTEDPYFTDCFISTVLVYVPSGILFLLTPYEIWTCF-NLGENSSRISRTWLN----FSRTILVGFLILLSLVEFIFELLREDNVLSNIVAPGIYFLTFLNVFILQIL------GRIKGRVSSGPLFVFWLLEVFAAGFSFR-NWRNIHRVPNT--DLVTLSTIVIQYPVVVILLFMGFWADGNNNYNKIGDNDLNPSSLRM------ASFTSKLTFSWFDPFIYKAWKKXVTDDDLYE----INDEFKSCGVLPSWDREMEKEIRRKHLKNKPINILWP-LVRSFKSTLLASSALQFFYSVFQFGAPQLVDLIINFVSDPKEPIWKGYLY---LFAICSITFINTLIYSQSNYYSYITGLKIRTSLTSSIFNKAVNLKSSSKKQMSVGETTNLMAIDSQRLMDFCLYIDMIWSSPLKIIIAMYLLWQVLGPASLAGLAVMILLIPINIVVGKKVKKFTAIQMQNKDKRIKLMDDILNGIKVLKLYAWEPSFIDAVTNFRVQEIGALKKSALINAVTSFMWTSAPFLVALASFTTYVLIDEKNILTPSTAFVSLTLFNLLRLPLNLLPMMIMKAIQSKVSLDRINLFLNKEDLDLLAISH--ESQGSHAVKMCNVSLSWETDEGLNTLEDIDLDIEKGSLVAIVGQVGSGKSSLLSGILGEMEIVRGSINVDGQTIYAPQQPWLQNETLRNNILFGKRFNKKLYRRVIDACALSPDLDMLPAGDLTEIGERGINLSGGQKARVSLARCTXNNGDIYILDDPLSAVDVHVGRHLFENVISSQTGLLKNKTRIFVTHGAIFLPQTDKIIVMKNGVISESGTYRDLIEKENGEFAQFLINYLVDEKENILKNDQDLKTIIKDLESTVGGSEELEKRLEAAQSDKSTALTDLIQGTKYLDENTSDQCSSIASRKGEDDLDEVVSNDLNERLIEEEKIESGGIKLNIYLNYFKRTGLLASFFGILFYFSYQGFSLGANLWLSKWS---TDRAAINSTSIRNHYLEIYAILGFFQSIFTMLGSVTIAIGTLNASMKIHGKLLENVLRAPLSFFDTNPLGRILNRFSKDIDVAXTTLPFNIRMMIAQSFNVLGTIVIICIALPWFFVIILPAVICYALIQKFYISCARQVKRIESISRSPIYSHFAETLTGIPTIRAFGMVHHFIDENVNKIDFNAKCYFPTVISSRWLAVRLETLGNILVIFVALFSITSRGTTDPGMVGLSLSYALSVTTILNMLITVSTDVETNMVSVERIKEY-ENIPQEAPYDLPNSDPPPN--WPEHGVIKFDNYKTRYRKGLDLVLKGINCTIQKGEKIGIVGRTGAGKSSLTLALFRIIEPSEGSIYIDGENIRFLGLGKLRSRITIIPQDPILFSGSLRMNLDPFEAFADRDIWIALEYSHLKSFVWNLGDGLNFSVLEGGRNLSVGQRQLICLARAILRKTQILVLDEATAAIDLETDDLIQSTIRSEFKDSTVLTIAHRINTIMDSNRIMVLDAGTIAEFDDPQNLLANPDSMFYSLVNDS 1516
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000003611 (supercontig:LSalAtl2s:LSalAtl2s197:49356:53594:-1 gene:EMLSAG00000003611 transcript:EMLSAT00000003611 description:"augustus_masked-LSalAtl2s197-processed-gene-0.4") HSP 1 Score: 1006.51 bits (2601), Expect = 0.000e+0 Identity = 541/1280 (42.27%), Postives = 792/1280 (61.88%), Query Frame = 0
Query: 375 EDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQVKDKLVDFTTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNS----KEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEID-------PKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWAD-YNQDHPDLATAST--TYYLGIYAGIGLVGMIINLIREFLHFVNCA----KASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+ AS SLL + W+ LLW GF++P+T L + + + T+ ++Q+ + +K + L+K G+ +I I F +L V PQI+KL+INH +S KE +W+G+ Y +L+ S + ++ Y +++ + ++++R+SL VYRK LKLSN +RK +VGE+ N+MSVD RI D P + L +SP IV+++ F+Y ELG A + G + I IPVN S + ++ Q+ Q++AKD R K+LNEVL G+++LKLYAWE ++ +I IR EI +++ A L + M F +SSTP +V + F +V +D ++LTAEK F + S N M++P+ FPF +V + VS KRIN+ L ++E+ P +N +D +AI + + W + + L INL I GSLTAIVGTVG+GKSSL+++ LGEM K SG+V+++G IAYVPQ++W+QN +LK+NILF + Y Y++V+ C L DL++L D TEIGE GIN SGGQ+QR+SLARA+YSDAD+Y+ D+PLSA+D+ VGK++F VL++ G +KDKTR+LVTH I++L + +I V+ G++ G+YQ+LL + + D + + P ++T+ +N KA +I++E G+V W VY Y+QSIG L I+ L + + S W + + Q+ AT YLG+Y +G +G + + FL ++ A KAS+VIH + +IMR+P+SFFD+ P GRI+NRFS DI D + + L C F + I+++I S P F P ++++ +IQ ++ +SRQ+KRL+S+++SPI++HFSE++ GL+SIRAY Q +F+ ES ++ C + ++ ANRWL R+E +GNL +F AI + + E + PG GL I+Y+L + LNW+ R E+ETN VA+ER+ EY E EW L D + WP++G V F++Y+ RY+ DLVLK I+ + E++GI GRTGAGKSSL+++LFRI+EA G+ILIDG+DIS LGLH LR +T+IPQ+P+LF+G LR NLDP +SD +IW+ L HLK +I LK GL+H I+EGG N S GQRQL+CLARALLR KIL+LDEATAAVD TD+ IQ TIR F CT++TIAHRL TI+D D+I V G + EFGSP EL + S +M+N AG
Sbjct: 157 KKDASFFSLLFYEWITPLLWKGFKKPITEDDLWNLNKDLTCGE-TSRRLDQYYFKSGNKKIGIP------------LMKAFGFEFVIGSTIKFFSDILSMVLPQIMKLMINHADSEFEMKERSWKGYLYPSMLIIVSFLQSVLLAKYFEIVFLVSMRIRASLTSLVYRKCLKLSNSSRKNKSVGEIVNIMSVDVSRIADLMPFLTLLWSSPFQIVVSVIFMYNELGWAIIGGTGILLITIPVNAILSYFGKKFQMKQMKAKDNRTKILNEVLGGIRILKLYAWEPSYINKIEGIRGVEIGILKKAAWLTSFMGFIWSSTPFIVALASFATFVMVDDRNILTAEKAFVTQSYINKMKMPMAXFPFVIVXAISATVSLKRINQLLTSDELQKDAVERVPMKINQKIDQG--DAIVIRDGNFKWSTEDSENTLSNINLRIKHGSLTAIVGTVGSGKSSLISAILGEMVKKSGKVRIKGQIAYVPQESWMQNTSLKNNILFGKPYDEEWYNQVLEYCCLTYDLSLLPAGDETEIGERGINLSGGQRQRISLARAIYSDADVYIFDNPLSALDSQVGKSVFNNVLNNNTGIIKDKTRLLVTHGISYLPHVHHIAVMLKGEIIHEGTYQELLEKKIIQTIEEEEEQE--------KDGVQENNINNYNNIPKTFDATV-------NNLEKAAIIQKEGLETGRVSWSVYKYYIQSIGFLGAFLIIFNQML----NQLFGFGSSIWLEAWTQEDYGNATIPKYRDLYLGVYGALG-IGQAVTI---FLLSLSVAMFTLKASKVIHNQTYDRIMRAPISFFDSTPQGRILNRFSKDISICDNILGSNIRQWLXCLFXFLGIVILIVSVLPLFLLFALPTSLVFILIQNIYVASSRQLKRLQSVTRSPIYSHFSESLNGLSSIRAYGAQSKFILESINKIDTNQRCNYPSIIANRWLAMRLETIGNLCIFGXAILTMTNPELVGPGKVGLVISYALILTQNLNWLXRQTSEIETNIVAVERLKEYAGLDIEKEWRLHKD--TSYNWPSQGKVEFKNYSLRYKANSDLVLKKINFTIFGGERVGIVGRTGAGKSSLSVALFRIVEAANGQILIDGKDISTLGLHDLRESLTVIPQEPLLFSGTLRSNLDPENAFSDHDIWNTLGSVHLKEYIRDLKDGLNHSISEGGLNLSSGQRQLMCLARALLRSCKILILDEATAAVDWETDEKIQETIRCYFPSCTILTIAHRLKTIIDYDKILVLDKGTVIEFGSPNELYMNSDSVFHSMINAAG 1396
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000011700 (supercontig:LSalAtl2s:LSalAtl2s812:79332:86643:-1 gene:EMLSAG00000011700 transcript:EMLSAT00000011700 description:"maker-LSalAtl2s812-augustus-gene-0.6") HSP 1 Score: 943.34 bits (2437), Expect = 0.000e+0 Identity = 517/1317 (39.26%), Postives = 808/1317 (61.35%), Query Frame = 0
Query: 340 EEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLALEDKASC-----------LSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQW-RTQVKDKLVDFTTTIRPFVSLWPILVKNHGWRLLISVVIA-IFHHLLPFVNPQILKLLINHVNSKE-PTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDP-SHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEM---EKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTI--LYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
EE + + + ++L+ + W + P ++++ L C S + FSWM L+W GF+RP+ L F S+N F+ W + + K ++ T+ P S++P L++++ W LL+ A + H LL +P +L+ LI S + P QG + IL + + T Y + +++++S+ +YRK+L++ + R T GE+ NLMSVD Q+IVD P + ++ + P I+ A+Y L LG + L+G+ V +LIP+N F + + Q+ Q++ KD+R+K +NE+L G+K++KLYAWE+ F + IS IRF EIK+++L ++ + M T SST +++ F VYV DP +H+L +EKIF S+SLFN++R PL M + VS KRINKFL + E++ + + + AI + ++ + + + L I++ + RG+L AI+G VG+GKSSL+++ LGEM K + V++ GS+AY PQ AW+QN+++KDNILF ++++ + YD+V++ C LESD+ D TEIGE GIN SGGQKQR+SLARAVYS +DIY LDDPL+ VD+HV K +F +V+ S G L+ KTR+LVTHN++FL +D I LK+G++ E G+Y++L+ FSE + + ++ +++ D + KVM E +++ + +E T + +EET G+V VY ++ IG L + + + + + LS W+D + Y+LGIYAG+G+ + I+ + ++ AS+++H L + I+++PMSFFDT P+GRI+NRF DI+ +D K+ F + ++ F + + II + P F +IP L I +Y++I +++SRQ+KRL S++ SPI++HF ET++G+ ++RAY + F E + R+ + F + A+RWLG R+ ++GN ++F +A+F+VLSR++++PG GL+++ SL I L+W+IRM +LE N VA+ERI EY++ EA W+L D K+ WP +G ++ ++ + +YR LD VL+ I++ + +KIGI GRTG+GKS+L L+LFR++E G+I IDG DI ++GLHTLRS++TIIPQDP LF+G LR NLDP ++ D E+ +L+HA+L+ + + GLD I E GEN S+GQRQLICLARALLRK K+L++DEATAAVD TD LIQ I+ F TV+TIAHRL T+LD +I V G I E+ SP LL+D SS M ++G
Sbjct: 701 EELMSSIIHVTLLLLNVLAHFWPEPPPRYSEYVRLVGVEGCHNPSPDTQCGYPSYIFFSWMSSLMWKGFKRPIKQKDLWDFIPSVNTALVNPHFLKHWNKIYTQTKFSNYPTSKSP--SIFPALLRSY-WPLLLKGAFAKLLHDLLLICSPMLLQYLILFSYSPDIPLGQGIALSVILFGNKILGTFFIARYFFYMVTVGMKLKTSITSLIYRKALRI-HSTRDDTTSGEIVNLMSVDVQKIVDLMPLLNTIWSGPLQIIAAIYLLINTLGYSALAGVLVMFLLIPINGFIAVRMKNAQMKQMKKKDERVKKMNEILQGIKIIKLYAWESSFSKLISSIRFEEIKLLKLSSKYFGFMMLTISSTTFFISLFTFIVYVVSDPENHILDSEKIFVSISLFNILRFPLNMLTHVIGGIASASVSLKRINKFLASEELEEGILVRS-NSHDHQAICIHPSSSFSWKGSSESLFKDISMDVNRGNLIAIIGPVGSGKSSLISALLGEMLFTSKGTNPVEIHGSVAYTPQNAWMQNVSVKDNILFGRKFNKNWYDEVLKACSLESDMEXFPSGDSTEIGEKGINLSGGQKQRISLARAVYSQSDIYFLDDPLAXVDSHVAKHLFEEVIGSN-GLLRGKTRILVTHNLSFLHLVDEIYFLKDGEITEKGTYKELMEKNCDFSELISNHANNKITNQSDSE--KVM------EKINEEGTKQPIE-------TNFKIYDEETLHTGQVGIRVYWYFLSKIGMLAGILAFSFFIISQILATGSSVWLSVWSDAKNN------TDIYYHLGIYAGLGVSNIFISTAGTLILSLSLLDASRILHGTLFQCIIKTPMSFFDTTPLGRILNRFGQDIEVLDTKMSFCIFGSMTGTFAYIATVTIISINVPIF--IIPTLAIFVVYFVILIVSLSSSRQLKRLSSVATSPIYSHFGETLSGINTVRAYSLEKAFYSEFERRLDEYQKRNFPVIMADRWLGIRINLIGNFIIFASALFSVLSRDTITPGQLGLNVSSSLAITSILSWVIRMYSDLENNIVAVERIKEYSNKESEAPWELEEDLKLNSSWPLKGEITIKNLSLKYRKDLDWVLRDINVHISPGDKIGIVGRTGSGKSTLALALFRLLEVNSGQITIDGVDIKKMGLHTLRSKLTIIPQDPTLFSGTLRLNLDPFGLFKDMELIESLKHAYLQDFLK--EDGLDKVIAENGENISLGQRQLICLARALLRKNKVLIMDEATAAVDSETDKLIQKAIKDNFRDSTVLTIAHRLQTVLDYSKIIVIDSGCIIEYDSPKNLLSDSSSTFYKMCLNSG 1986
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000001655 (supercontig:LSalAtl2s:LSalAtl2s128:1836948:1854487:1 gene:EMLSAG00000001655 transcript:EMLSAT00000001655 description:"augustus_masked-LSalAtl2s128-processed-gene-18.4") HSP 1 Score: 683.33 bits (1762), Expect = 0.000e+0 Identity = 402/1174 (34.24%), Postives = 655/1174 (55.79%), Query Frame = 0
Query: 474 FVNPQILKLLINHVNSKEPTWQ-GFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDP-KNVNHTLDDAAKNA---------IELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVR---GSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGL-KGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMV 1632
F P +L L+ + + + G+FY L S+ + I + ++ +++R+S++ ++Y+++L +S +Y+ GE+ N MS+D R+V+ +P+ + + P +V+ LY L+ ++G++ G+ ++IP+N + L + AKD R+K++ E++ G++V+K Y WE+ F + + R EI ++ L A+ + ++STP+++++ F Y A+ + LTA K+F S++LF ++ P FPF + ++ VS KR+ +FL+ I+ K D+ K + I++ A+ + +D L I++SI R ++G VG+GK++ L + LGE+EK SG++ VR IAYV Q WIQN +++DNILF + Y +Y KV++ C L+ D L DHT GE G SGGQK R++LARA+Y D DIYL+DD S++D +VG ++T+V+ LK KTR+L THN +++ + +I +K+G+ L+ P S+ +PD T + + + SN D +EEE G V + +Y Y Q+IG+ L I+ L LSHW + D+ T T +Y+ +Y+G+ + I+ LIR FL A+++IH+ LL ++R+ + FFD+ P GRI+NRFSSD AID +PF L+ L F +++ + P V+ PL + YY IQ + SR +KR+ S+S SPI+ HF+ETV GL IRA + RFL E++ V+ + SA+ WL R++++G++VVF A+ +V++ ES+ G+ GL+++Y+L + L ++ E E VA+ER +Y + E + L+ + + WP +G V F+ RY+D L VL ++ + + EKIGI GRTGAGKSSL +LFR+ G I++DG I L L R + +IPQDP +F+G +R NLDP +SD E+W +++ ++L I GLD I +GG++ S+GQ+QL+CLARA++ K++ +DEATA+VD TD LI+ ++ F TVITIAHR+ T+L+ DRI V S+GQI E G P +L+ P+S + ++
Sbjct: 324 FFCPLLLNRLVKFMEDPKADLRWGYFYAFSLFVSTFLVAICNTQFNFKMNELGLKVRASVIQSLYKQTLSVSEANLNKYSRGEIINFMSIDVDRVVNFAPSFHAFWSLPFQMVVTLYLLHQQVGVSSFVGVGFAILMIPINKVIATKIGSLSGHMMSAKDDRVKIIAEIIEGIRVIKYYCWESFFTDKTNSHRNNEIYYLKWRKYLDAVCVYLWASTPVIISVSTFATYSAL--GNPLTAAKVFTSMALFAMLSGPFNAFPFVINGLIEANVSIKRLARFLSLPSINRIKYFTEYKDENTKASKEIETKIPDIQIMEASFGFTKDCFT--LRNIDVSIKRQEFVGVLGPVGSGKTTFLNAILGELEKQSGKISVRDPLSGIAYVQQVPWIQNKSIRDNILFGEMYIHGKYTKVIKACCLDHDFKHLHRGDHTIAGEKGAALSGGQKARIALARAIYQDKDIYLIDDVFSSLDVNVGYKVYTEVM---LNLLKRKTRILCTHNPQYINDANIVIKIKDGEFESVKQSTHLV----------------PTST-----------------SPDFSYDTSMFDFKDNSN-VIDDSVEEEMQETGVVAYRIYKKYWQAIGTYLAPTILISIFLMQVASNTTDLWLSHWV--STDNFQNNTEDTDHYIYVYSGLAVFHTILTLIRAFLFAYGGIHAAKIIHDLLLGVLLRAKIYFFDSTPAGRILNRFSSDTYAIDDSLPFILNIFLSQIFGVFGRVLVCVYAVPWILIVLLPLGLFYYEIQCKYRPGSRDLKRISSVSLSPIYEHFNETVHGLKIIRASKASQRFLLENEELVECNQKARYAAFSASLWLEIRLQLIGSIVVFSIALISVINFESVDAGLVGLAVSYALGMTXRLAEVVVSFTETEKELVAVERAYDYIDRIYEESYSGVLN--MPYNWPNQGVVEFKDIRLRYKDHLPYVLNKVNFKTKPKEKIGIVGRTGAGKSSLIAALFRLSSFSHGEIMVDGIRIRLLPLIDFRRQFAVIPQDPFIFSGTIRQNLDPYAQHSDQELWDSIKLSYLYNIIYSFGSSGLDTLIGDGGKSLSIGQKQLLCLARAIITSAKVVFIDEATASVDKETDRLIRNVLKTAFNDKTVITIAHRIETVLNSDRIFVMSNGQIIEEGKPEDLIKSPNSEFRKLI 1452
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000752 (supercontig:LSalAtl2s:LSalAtl2s111:55855:93761:1 gene:EMLSAG00000000752 transcript:EMLSAT00000000752 description:"maker-LSalAtl2s111-augustus-gene-1.10") HSP 1 Score: 582.022 bits (1499), Expect = 9.119e-180 Identity = 387/1215 (31.85%), Postives = 630/1215 (51.85%), Query Frame = 0
Query: 497 FFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSP----CTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLV-MFPFTLVECVKVVVSFKRINKFLNANEID--PKNVNHTLDDAAKN--AIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQE-------------------STLVVELEKTSNGTKADLIEE------------ETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTE-AIAHYSLSHWADYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFV-------------------------NCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQ--ARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVL---SRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEA---EWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+F++GIL+ + + + Y L + +Q+R + +YRK+L LS + + ++G+M NL+S D R + + + L +P C ++I YF G+ ++G A+ I + K +L++ D R++++NE+L+G+KV+K+YAWETPF++ +++ R F P+ + +V+F V + A+KIF LF+ +++PL FP + + +VS KRI +FL NE+ +NH + +E+T + W + + + L I+ S+ G L AI+G VG GKS+++ S LGE G++ ++G I+Y Q+AWI + +++ NIL + +Y +V+R C LE D+ D+T +GE GI+ SGGQK R++LAR VY+ ADIY+LDDPLSAVD HVG+ +F + + L DKT +LVTH + FL +NII+L +G++ SG+Y+KL++ F +L + TS+ SD +L DV+++ E ++L+V + T+ D E ET + G V +Y Y + G V +L T ++ + L W + D L T+Y Y + L + + +F +F+ +C ++SQ +H+++ +++ + FFD NP GRI+NRFS DI + D+ +P L I ++I + P I L ++ I+++++ SR +KRLE +++SP+F+ + ++ GL +IR+ + ++ + E + + +FL V NR+ +++ L +F A++ ++ +R++ + G GLS+T SL + + W +R E+E ++ER+ EY ++P+ + D+ LDP WP +G + F + +Y VLKG + +G+I IDG +I +L L +R +I+IIPQDP+LF G +R NLDP + Y + IW ALE A L + L+GGL+ E++EGG NFSVGQRQL CLARA+LRK K+L++DEATA VD +TD LIQ IR EF+ CTV TIAHRL T++D DRI V S G+I E G+P +LL+DPS+ MVN G
Sbjct: 459 YFWSGILVGAGVIFVLFDQRYWYLSLKTGMQLRIAASAIIYRKALTLSKASLGRSSIGQMVNLLSNDVNRFDNSTVFLQYLWVAPIQFICVMLITSYFA----GIEAVAGGALLIFFIFFQTYMGKMFSKLRLMTASKTDIRIQIMNEILDGIKVIKMYAWETPFVQLVTNARNR------------------FVLLPVFLLMVLFGVEI--------NAQKIFLIFGLFDAIKLPLTHFFPSAISASSEALVSMKRIEEFLLLNELRDVQSKINHVILPGRYEPLTVEVTKISGKWLDSSNEFTLKNISFSVEIGELCAIIGPVGCGKSTIIQSLLGEFPVSYGEINIKGRISYASQEAWIFSGSVRQNILMGKPLIDKRYREVIRVCALEHDVREWPDGDYTFVGEKGISLSGGQKSRINLARCVYASADIYILDDPLSAVDPHVGQQLFDTCI---QKFLSDKTVILVTHQLQFLKNANNIILLNSDGEIEASGTYEKLMSQ-SGFVTYL-EATSEEEDSD--------LLSDVLSDVKSDGEYMRSQKKKLKKGVRSRRSSTSLLVPVPYIGGSTERDTFPEEKGSQEWKMGSKETIIEGSVSLSLYHKYFVAGGGFFKFLCVYFLSLITHTLFVVSDWWLRLWTNA-ADARKLGPLPPTFYFSEYQDMTL-QITADFQVDFFNFIYCSIYLSLIIILLFSAQLSVRQLFMSCMRSSQTLHDRMFEKVAFTNSRFFDLNPNGRILNRFSKDIGSXDELLPPAL-------LSGSGIFILISMTNPLIVVGIVVLLLILLTIRKYYLNASRAVKRLEGITRSPVFSQLASSLDGLTTIRSMKIEEMLIEEFDYLQDIHTSSYYSFLVV--NRFFAFCGDLM--LSLFTASMVSMFLFYNRDA-TGGDVGLSLTLSLALCGMIQWGLRQSAEVENFMTSVERVAEY-GDLPKEKGLKGDIKLDPS----WPDKGVIEFSNVNLKYDGTTPYVLKG-------------------------------LTEPEGKIFIDGVNICRLSLQDVRKKISIIPQDPLLFKGTIRKNLDPFDEYGELAIWHALEQAKLSVAVSELEGGLETEVSEGGNNFSVGQRQLFCLARAILRKNKVLIMDEATANVDPMTDSLIQEAIRTEFKDCTVFTIAHRLYTVMDSDRILVMSDGEIKELGAPLDLLSDPSNIFYQMVNQLG 1580 HSP 2 Score: 236.498 bits (602), Expect = 6.500e-63 Identity = 129/286 (45.10%), Postives = 172/286 (60.14%), Query Frame = 0
Query: 1349 LNWMIRMLCELETNSVALERILEYTHNVPEA--EWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMV 1632
+ W +R E+E ++ER++EY E E D+ LDP WP +G V F + + RY VLKG++ + S EKIGI GRTGAGKSS+ +LFR+ E +G I IDG DI ++GL +R +I+IIPQDP+LF G++R NLDP ++D +IW+ALE A L + L GLD + E G NFSVGQRQL CLA A+LR+ K+L++DEATA VD TD LIQ IR+EF+ CT EFG+P +LL DP++ L MV
Sbjct: 2 IQWGLRQSAEVENFMTSVERVVEYGELPKEKGLESDIKLDPS----WPDKGVVEFSNVSMRYSQHQPNVLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEP-EGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCT--------------------------EFGTPKDLLKDPNNLLSRMV 256 HSP 3 Score: 57.7658 bits (138), Expect = 2.983e-8 Identity = 54/214 (25.23%), Postives = 96/214 (44.86%), Query Frame = 0
Query: 772 KNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASF--LGEMEK----------LSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAV----DAHVGKAIFTQVLDSTE-GCLKDKTRVLVTHNINFLDKM 968
K +E +N ++ + + +L +N I+G GAGKSS++++ L E E G + +R I+ +PQ + N +++ N+ E++ Q + +L + L H + + E G NFS GQ+Q LA A+ + ++D+ + V D+ + +AI + D TE G KD L+ N L +M
Sbjct: 47 KGVVEFSNVSMRYSQHQPN-VLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEPEGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCTEFGTPKD----LLKDPNNLLSRM 255
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000090 (supercontig:LSalAtl2s:LSalAtl2s1014:9799:23913:-1 gene:EMLSAG00000000090 transcript:EMLSAT00000000090 description:"maker-LSalAtl2s1014-snap-gene-0.6") HSP 1 Score: 397.512 bits (1020), Expect = 1.667e-119 Identity = 280/940 (29.79%), Postives = 470/940 (50.00%), Query Frame = 0
Query: 725 MRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKN-------AIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEM-EKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWAD--------------YNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAY-VIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSET-VTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVL-GNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPE--AEWDLPLDPKVGHVWPAEGA----VSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSR-ITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMV 1632
MRIP + P + + +VS KRI+ +LN E+D N D +K+ +I++ + + D+ LL IN S G LTA+VG VG+GKS LLA+ GE+ ++ G + + YV Q W+++ T++DNI F Q Y+SSQY KVV CQL D + D T + NG SGGQ+QR+ ARA+Y +A +YL+DDPLSA D+++ IF + +G L+ KTR+L+T+ + + MD IIV++NG V E S +++ K+F + + ++ S +P + + P + D+IE K+ + +Y YV ++G++ F+ + Y + + + LS W + YN+D ++ Y+ +Y +G + + L KAS H+ +L+++ +P++FF + P G IINRFS D+D D +P L + + + ++I + P A+ ++ PL +++ + + ++ SR +KR + + + HF ++ V G +IR Y + ++ E + + + + + + + + L R++++ G + A E S ++ LS+T SL ++ + R +E V++ERI E +P+ + LP G P + FE ++ +Y + +K + VR EK+G+ GRTG+GKSSL L+L ++E KG+I IDG D+S +R + IT D LF G++R+NLDP++ ++D IWS L+ A +K L GGLD + E G N S+ LI ++DEA +A+ L +++ I T F T+ IAHR+ +L CD+I V +G IAEFG+P L+ S K+M+
Sbjct: 1 MRIPFRLLPSCISALSQGIVSIKRIDSYLNREEVDSVKSN----DFSKSPRPEDGYSIQVQDCNYSIDK---LKLLKNINFSTRVGELTAVVGKVGSGKSCLLAALCGELNQRGKGSSLINKDLVYVTQNIWLKSATIRDNITFGQPYNSSQYQKVVSLCQLGQDFKDMYRGDLTYLASNGSTLSGGQRQRIGFARAIYQNAQVYLMDDPLSACDSNLKAQIFHNTI-GPKGFLQKKTRLLITNQSSLIPLMDRIIVIQNGTVEEKDSAEEV----KSFE--IAKKSTKKQGSFHEPPKDNYLHPAL----------------------DNYDIIERR-----KIPFSLYKYYVLNLGTVPFIIALVGYLISQCFDVCSKLWLSRWTNLSSTNINDTNYRHIYNEDTRNM-------YIVVYGILGWCQSLAYFLSVLLINSRSLKASSHFHDVILRKVFGAPLNFFWSTPKGTIINRFSKDMDEADMFLPNTLKNFAYQAVKILGTLIIALIAFPITAFFIVCPLGLIFIEVVKSYLMASRFLKRTSATKLAMVLKHFGDSAVHGGTTIRCYGVESDYIDEHMSLIDEHQSVSLMEIISEAXLFLRLQLIAGTFIGILATALVFFPSEGNSSSLSALSLTSSLTVLQDIFLFTRYAAFIEKAMVSIERIKECEDLIPQDPSSGLLPSIITNGSKRPKNHQSRYYIQFEDFSGKYSSLKNASIKNFTLNVRLGEKVGVVGRTGSGKSSLILALSGLLEVEKGKIFIDGVDMSSGTARNIRKKDIT----DAALFKGSIRYNLDPDDRFTDEYIWSVLDEAQMKEFFVQLPGGLDFSLKENGSNISLAGSNLI-------------IMDEAXSAMTLESEERILNTYFSRFSSSTIFVIAHRIQPLLACDKILVLENGTIAEFGNPESLIKSQKSIFKSML 875
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000741 (supercontig:LSalAtl2s:LSalAtl2s111:116041:261433:1 gene:EMLSAG00000000741 transcript:EMLSAT00000000741 description:"maker-LSalAtl2s111-snap-gene-2.14") HSP 1 Score: 365.54 bits (937), Expect = 4.595e-103 Identity = 275/905 (30.39%), Postives = 462/905 (51.05%), Query Frame = 0
Query: 378 ASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQF---PRSMNVTDNTATFMNQWRTQVKDKLV-DFTTTIRPFVSLWPILVKNHGWRLLISVVIA-----IFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWAL-MNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMF-PFTLVECVKVVVSFKRINKFLNANEIDP--KNVNHTLDDAAKNA--IELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKD----KTRVLVTHNINFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDE----PKVMLPDVIAETPDQQESTLVVELEKTSNGTKA----DLIEE-------ETALVGKVKWEVYMNYV-QSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWAD-YNQDHPDLATASTTYYL---------GIYAGI--GLVGMIINL----IREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTIL 1230
A+ LS + F W+ LL DG + LP +S ++DN +W+ +++ L D T+ R SL L++ G L + + +F L P QI+ N + PT Q + ++ +L+ S + + H Y + +++R + +Y+KSLKLS + + +VG+M NL+S D R + L +P ++ + +G++ + G A+ + IP+ + K L++ DKR++++NE++ GMKV+K+YAWE PFM +++ R EI+ I+ A + F F+S+ +++ ++ F + + + V++++ IF LFN +R+ L +F P T+ + +VS RI FL EI ++ H + + + IE+ N + W + L ++ + + LTAI+G VG+GKS++L + LGE SG + + G I+Y Q+ WI + T++ NIL + +Y KV++ C LE DL +DHT +GE G+ SGGQK R++LAR+VYS+AD+YLLDDPLSAVD+HVG+ ++ E C+K+ KT +LVTH I +L NII+L G++ + G+ KLL + F+ FL+ + S D DE PK L I +++S++ + + T A D+ E E+ + G + +Y Y G +F F+ + L + L W + + + A AS+ L IY GI LVG +I IR+FL + C K+S+ +H ++ ++++ + +FFD NP+GRI+NRFS DI ++D +P LSDT F + V + +I S+ P V+ PL ++
Sbjct: 17 ANILSKIFFIWVLPLLRDGQNKAFDIPDLPSALTEDKSRYLSDN---LEREWKKELEKGLRYDNTSKKRYSPSLLRALIRTFGSSLGVYGAFSFIEECVFRLLQPLAISQIVLYFSNSNHGISPT-QLYIWSAVLIMSGVLYVFSHHWYFFGVVQVGMRIRIACSALLYKKSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFIHYLWVAPLQFILVSIITWYMVGISSMCGGAILLVFIPLQTWIGKQFSRLRILIAGKTDKRIRVMNEIIEGMKVIKMYAWEYPFMEVVNETRRDEIQTIKKTYEYKAFNLGFFFTSSRVVLLLIFFLMIIG---NEVISSKNIFLIFGLFNTVRLSLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEVSLRIEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLY-------EECIKNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLLMSERDFTSFLVA-QEEETDSIFDEDELALTPKKSLN--IENYMRRRQSSVSSIGSRATIDTNAMEYNDIPNEGRRTQTTESKVKGSISVALYKKYFYAGGGKWIFFFVYGLNILSQLLFVSTDWWLKQWTNAADARTNNYANASSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISIRKFL--ILCLKSSKNLHLEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGSLDXLLPLALSDTSLIFLNAVGMFGLIISTEPK---VLIPLGLI 899 HSP 2 Score: 314.309 bits (804), Expect = 6.535e-87 Identity = 230/765 (30.07%), Postives = 387/765 (50.59%), Query Frame = 0
Query: 730 VMFPFTLVECVKVVVSFKRINKFLNANEIDP--KNVNHTLDDAAKNA--IELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKD----KTRVLVTHNINFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQ---ESTLVVELEKTSN-GTKA----------DLIEE-------ETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHW--------AD--------YNQDHPDLATASTTYYL-----------GIYAGI--GLVGMIINL----IREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNV-SANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRD-GLDLVLKGIDMEVRSNEKI 1429
+ FP T+ + +VS RI FL EI ++ H + + + IE+ N + W + L ++ + + LTAI+G VG+GKS++L + LGE SG + + G I+Y Q+ WI + T++ NIL + +Y KV++ C L+ DL +DHT +GE G+ SGGQK R++LAR+VYS+ D+YLLDDPLSAVD+HVG+ ++ E C+K KT +LVTH I +L + +NII+L G+ G+ KLL + F FL+ ++ + + + +A TP + E+ + S+ G++A D+ E E+ + G + +Y Y + G F V Y L ++ I + ++ W AD NQ H + A+T+ + IY GI LVG +I +R+F+ C K+S+ +H ++ ++++ + +FFD NP+GRI+NRFS DI A+D +P LSDT F + V + +I S+ P + + I+ ++++++ SR +KRLE ++KSP+ + S T+ G+++IRA + ++ F E +Q F + S R+ G V+ G + + A + ++ G G+S++ S+ + + W +R E+E ++ER+ EY ++P +E L D K+ WP +G + F + +Y D G +LKG+ + S EKI
Sbjct: 1152 LFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEESLRIEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLY-------EECIKKYLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLLMSERDFKPFLVA---------QEEETDSIFHKNELALTPRKSLNIENYMRRRQSSVSSIGSRATIDTNVMEYNDIPNEGRRTQTTESKVKGSISVALYKKYFYADGGKWMFFFV--YGLNISSQLI--FVMTDWWXKQWTNAADARKKFGDIRNQKHFFSSYANTSSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISVRKFIFL--CLKSSRNLHSEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGALDDLLPIALSDTNLIFLNAVGMSGLIISTEPKILIPLLAILIILLALRKYYLNASRSVKRLEGITKSPVISQLSTTLNGISTIRASKLENNFASEFHY-LQDIHTAAFFSFQSVTRFFGFWVD--GIVSINVXATVVIFVFFNVKGGDIGISLSLSVLMARXIQWGLRQSAEVENYMTSVERVAEYG-DLP-SEKRLTSDKKIDPSWPNKGVIKFHNVKLKYDDQGGPYILKGLTFTINSFEKI 1889 HSP 3 Score: 60.077 bits (144), Expect = 5.449e-9 Identity = 55/209 (26.32%), Postives = 96/209 (45.93%), Query Frame = 0
Query: 1416 LKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHE-INEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDL-VTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVF-SHGQIAEFGSPAELL 1621
L+ + +V E I G G+GKS+ I++A+ G + DIS G +I+ Q+P +F+G +R N+ + L+ L+ + DH + E G S GQ+ I LAR++ + + +LD+ +AVD V L + I+ TVI + H++ + D I + + G+I + G+ +LL
Sbjct: 440 LRNVSFQVHKRELTAIIGPVGSGKST-------ILQALLGEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPD-RDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECIKNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLL 634 HSP 4 Score: 55.4546 bits (132), Expect = 1.442e-7 Identity = 56/220 (25.45%), Postives = 101/220 (45.91%), Query Frame = 0
Query: 1416 LKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLK-GGLDHE-----------INEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDL-VTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVF-SHGQIAEFGSPAELL 1621
L+ + +V E I G G+GKS+ I++A+ G + DIS G +I+ Q+P +F+G +R N+ + + + H K ++ LK LDH+ + E G S GQ+ I LAR++ + + +LD+ +AVD V L + I++ TVI + H++ + + + I + + G+ G+ +LL
Sbjct: 1219 LRNVSFQVHKRELTAIIGPVGSGKST-------ILQALLGEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNI---------LLGAPMNH---KRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECIKKYLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLL 1413
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000002016 (supercontig:LSalAtl2s:LSalAtl2s1361:43077:48755:-1 gene:EMLSAG00000002016 transcript:EMLSAT00000002016 description:"augustus_masked-LSalAtl2s1361-processed-gene-0.2") HSP 1 Score: 313.923 bits (803), Expect = 8.146e-87 Identity = 191/621 (30.76%), Postives = 319/621 (51.37%), Query Frame = 0
Query: 1059 GKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAI----FAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYR-------------------DGLDLVLK--------------------GIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
G + V Y ++ G L F V + + + + L W+ + + D A ++Y + + L+ + NLI + + A+A +H +++ IM P+ F+ PIGRIINR S DI +DQKIP + + F + + +P F P+ +Y+ + F+ +SR+++RL+S++++P+ +HFS+T++GL ++RA+ +Q RF++E +V + + S RWLG ++ G + VF + + F RE S GLS+ YSL + L W+++ +E A+ER+LEYTH P E D + V + S S+ R R D L+++ G +E+ +K+GICGR+G+GKS+L + + R+ ++G I I+G +I+ + L LR + IPQD VLF+G +R NLDP +SD IWS L+ A + GLD + E G+NFS+GQRQ + + +ALLR+ ++++LDE+T+A+D + + T+ FE T+I++AHRL+ I++ +R+ V G+I E G+P ELL P A+ AG
Sbjct: 1276 GSIDIGVLTVYFKAGGIFLAGFFVILSFVLQSVKVYMDFLLRDWS-MEEKNSDKLIAYFSFYGSLSVIVILISCVANLIGQLIG----ARARTKLHNDMIQNIMYCPLELFEAFPIGRIINRISHDIFIVDQKIPPCIQRLIMLSFVCIAALAXNSIQSPVFLIFALPMISIYWWLXHFYRRSSRELQRLDSITRAPVLSHFSDTLSGLITVRAFGEQTRFINELCEKVDTNTSAFLILQSGCRWLGVYLDAAGAIFVFLSILVNLFFPRKGREVTSSASIGLSVNYSLLVPIYLAWVVKFAANIENYMNAVERVLEYTH-FPSEEEDFS---EFQAVHASSMNSSRRSFLLRGRGKHDEIEEDVRVSGDFLQNDSEGLIIRFNSVCLAPSFEYRRLPGIQQGFSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFEDSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGFFSALWRAAG 1887 HSP 2 Score: 219.164 bits (557), Expect = 1.735e-57 Identity = 198/723 (27.39%), Postives = 338/723 (46.75%), Query Frame = 0
Query: 371 HLALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQV-KDKLVDFTTTIRPFVSLWPILVKNHGWRLLI-SVVIAIFHHLLPFVNPQILKLLINHVNSKEPT-------------------WQGFFYTGILLASSTVSTITF----------HVYQQLLSVSAIQMRSSLLGAVYRKSLKL----SNKA---RK----------------------------QYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAV-FAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTL-------DDA--------------------AKNAIE----LTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQ--VRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLK-----DKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKL 988
H+ L ++AS S L F W++ +L G+R PL L + P+ + T + + +T + +DK ++I LW + N W +I + +F +L + + +++N + ++ + FF + + VS + F LL+VS I+ +++L +Y KSLKL SN RK +G +TNL S D I + N+ + P I++ L+ LY +LG++G+SG + +++P+ V K E L ++D RL E L MK +KL E ++RI R E+ ++ + LW+ M F S + LVT + ++V ++ H TA +F S++L + + + L + P T+ +K VS +R+ +FLN E+ N+ L DD AK E + N T W + +L INL I GSLT ++G G+GK++L++S + EM++++G V+ V ++A + Q+ W+ N T+KDNIL + + +Y KV+ C L++D+ +L H D TEIGE G+ SGGQ+QR+++AR +YS + +D P S++D+ + +F EG LK +T L T ++FL + D+I+ LK+G + G+ Q +
Sbjct: 243 HVYLYNEASSFSRLTFWWLNPILTQGYRAPLEIDDLHKLPKE----ERTKKYFQKLKTLLSRDK-----SSI-----LWECITMN--WSFVILGGLFRLFADILGYACALSINIIVNSIAAENENASLHLISNVTINPLKDTRYYDSFFVSELFFDPRVVSIVIFLAALGQGALSQTSNHLLTVSGIRAKNALHVLLYEKSLKLPVGSSNPMQIHRKINLKPLNDEGKGCMGGSCSLDEDYSNEGNIDIGFITNLASEDIINIRELIWNVHYIWALPLKILVLLFLLYDQLGISGVSGAILGTCVILPLQVLTGKLMSENNKLILCSQDNRLFKSTETLASMKTVKLATMEEWALKRIRCARTKELIFLRRDSFLWSFMAFLASISTTLVTTLTLGLFVLLE-DHNFTAADLFTSMALLSQLTVCLSVVPVTVPIFIKGKVSTQRLAEFLNRAEVSIYKQNNKLNKHCTYFDDRKDDDEEEEEEEEESEIFIQRAKRLPETCFTVENGTFAWPK-CETNVLQSINLEIKTGSLTIVIGPSGSGKTALISSLIEEMDRITGSVKWNVPDTVALLGQRPWLLNTTIKDNILLGRPFKEKRYKKVIAACDLQTDIDLLPHGDDTEIGERGVLLSGGQRQRLAIARCLYSKSYCTFMDAPFSSLDSKITSHVF------EEGVLKILLKRRRTVFLTTERLDFLHRADHIVALKDGMIKAQGTIQDV 941 HSP 3 Score: 72.4034 bits (176), Expect = 9.451e-13 Identity = 55/216 (25.46%), Postives = 102/216 (47.22%), Query Frame = 0
Query: 797 NLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGS-------------IAYVPQQAWIQNMTLKDNILFDQEYSS----SQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAF 995
+L IP I G G+GKS+LL + L G + + G + +PQ A + + T++ N+ + ++S S DK DC + T + ENG NFS GQ+Q +++ +A+ + +LD+ SA+D + A+ +L++ E D T + V H ++ + + + ++V+ G++ E G+ ++LL F
Sbjct: 1671 SLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKA--DCG--KTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFE----DSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGF 1878 HSP 4 Score: 55.4546 bits (132), Expect = 1.595e-7 Identity = 47/208 (22.60%), Postives = 90/208 (43.27%), Query Frame = 0
Query: 1415 VLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVD------LVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGS 1616
VL+ I++E+++ + G +G+GK++L SL ++ + G + + D + ++ Q P L ++ N+ + + + L+ I L G D EI E G S GQRQ + +AR L K+ +D +++D + + +++ ++R TV RL+ + D I G I G+
Sbjct: 744 VLQSINLEIKTGSLTIVIGPSGSGKTALISSLIEEMDRITGSVKWNVPDT-----------VALLGQRPWLLNTTIKDNILLGRPFKEKRYKKVIAACDLQTDIDLLPHGDDTEIGERGVLLSGGQRQRLAIARCLYSKSYCTFMDAPFSSLDSKITSHVFEEGVLKILLKRRR---TVFLTTERLDFLHRADHIVALKDGMIKAQGT 937
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000007660 (supercontig:LSalAtl2s:LSalAtl2s445:12562:17493:1 gene:EMLSAG00000007660 transcript:EMLSAT00000007660 description:"maker-LSalAtl2s445-augustus-gene-0.18") HSP 1 Score: 128.257 bits (321), Expect = 2.459e-30 Identity = 130/494 (26.32%), Postives = 218/494 (44.13%), Query Frame = 0
Query: 1153 IHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQK----IPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAV---------LSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVW-PAE---GAVSFE----SYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRIL-IDGQDISQLGLHTLR-SRITIIPQDPVLFTGNLRFNLD---PNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAEL 1620
+ + L I+ ++FFD + G I++R S+D+ I GL + V++ +I T ++P + + I + S++ + ++K+ E ++ + ++R + +D + V K + N LG + V FF + +S ++L+PG + I ++ + + L + RI EY VP L P G V P G V F+ SY TR VLK + + ++ + + G +G GK+++ L R + G L IDG +I L LR S I I Q+PVLF ++ N+ PN +D E++ A + AH+ + G + E G S GQ+Q I +ARALL+ IL+LDEAT+A+D ++ ++Q + + + T + IAHRL+TI + D IAV G +AE G+ A L
Sbjct: 188 LRKDLFNSIICQDIAFFDEHKTGEIVSRLSADVQEFKSSFKLVISQGLRSSAQASGCIVSMYMISPQMTSAMGVIVPTVILGGTYIGSYLRVLSKKAQ--AQVAKATAVGE--ECISNIRTVRGFAMEDAEMELYSREVDKTRDF-------NEALGLGIGVFQGASNFFLNSIVLGTITYGGYLMSDDNLNPGQLMSFLVSVQTIQRSITQVSLLFGHLVKGMASGSRIFEYIEKVP-------LIPISGGVKIPYHSFFGDVEFKNITFSYPTRPEQA---VLKDFSLRIPPSKTVALVGTSGGGKTTIAALLERFYDINGGGSLEIDGINIRDLDPSWLRGSAIGYINQEPVLFATSVIENIRYGRPNA--TDNEVYEAAKAAHVDDFVRTFPDGYSTILGERGVTVSGGQKQRIAIARALLKNPPILILDEATSALDAESERIVQEALDKLSKGRTSLVIAHRLSTIKNADVIAVIDKGVMAEIGTHAAL 658 HSP 2 Score: 85.1149 bits (209), Expect = 8.022e-17 Identity = 63/243 (25.93%), Postives = 120/243 (49.38%), Query Frame = 0
Query: 775 IELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLA--------SFLGEMEKLSGQVQ------VRGS-IAYVPQQAWIQNMTLKDNILFDQEYSS-SQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQ 1001
+E N T ++ + +L +L IP A+VGT G GK+++ A + G +E ++ +RGS I Y+ Q+ + ++ +NI + + ++ ++ + + ++ + T +GE G+ SGGQKQR+++ARA+ + I +LD+ SA+DA + I + LD K +T +++ H ++ + D I V+ G +AE G++ L G +S + Q
Sbjct: 433 VEFKNITFSYPTRPEQAVLKDFSLRIPPSKTVALVGTSGGGKTTIAALLERFYDINGGGSLEIDGINIRDLDPSWLRGSAIGYINQEPVLFATSVIENIRYGRPNATDNEVYEAAKAAHVDDFVRTFPDGYSTILGERGVTVSGGQKQRIAIARALLKNPPILILDEATSALDAE-SERIVQEALDKLS---KGRTSLVIAHRLSTIKNADVIAVIDKGVMAEIGTHAALKRKGGIYSRLIEQ 671
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|82231164|sp|Q5F364.1|MRP1_CHICK (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1152.12 bits (2979), Expect = 0.000e+0 Identity = 638/1535 (41.56%), Postives = 921/1535 (60.00%), Query Frame = 0
Query: 179 DPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFV----NLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTRE----EWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLALEDKASC-------LSLLLFSWMDGLLWDGFRRPLT---------------------------WTRLPQFPRSM---NVTDNTATFMNQWRTQVKDKLVDFTTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKE-PTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYT-----------SDPMSSDKDPDEPKVMLPDVIA---------------ETPDQQESTLVVELEKT-SNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDLATASTTYY----LGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+PF+D N TW+T +P+ T C ++T+LV +PC + P + +Y R H + L K L L++++ +L W S+++ P + + LG+ ++LA + + S + +FWL LLC + I ++A++ E +V F TYF ++LV I C+ + P ++ A+ D C LS + F W+ GL+ G RRPL W + + P +M + ++ N + + L+ + SL +L K G L+S + H LL F P+ILKLLIN VN+K P WQG+FYTG+L + + T+ H Y + V+ ++++++++G +YRK+L ++N ARK TVGE+ NLMSVDAQR +D + + + ++P +++ALY L+ LG + L+G+AV +L+P+N + + QV Q+++KD R+KL+NE+LNG+KVLKLYAWE F ++ +IR E+KV++ A L A+ FT+ P LV + F VYV ++ +++L A+K F SL+LFN++R PL + P + V+ VS KR+ FL+ E+DP ++ A+ +I + NAT +W + T P L+ IN ++P GSL A+VG VG GKSSLL++ LGEM+K G V V+GSIAYVPQQAWIQN TL+DNI+F +E + S+Y +V+ C L DL IL D TEIGE G+N SGGQKQRVSLARAVY +AD YL DDPLSAVDAHVGK IF +V+ +G LK+KTRVLVTH +N+L +MD I+V+ +G+++E GSYQ+LL AF+EFL Y S P + P E V++ D ET Q + EL+K + L E +TA G+VK VY Y+++IG + V ++ ++Y LS W D D T Y LG+Y +G+ I + AS+ +H LL ++RSPMSFF+ P G +++RFS +ID ID IP + + F+ + +II +TP A VIPPL ++Y ++QRF++ TSRQ+KRLES+S+SP+++HF+ET+ G++ IRA+++Q RF+ ++ +V + + ++ ANRWL R+E +GN +V FAA+FAV++R LSPG+ GLS++YSL I LNW++RM +LETN VA+ER+ EY EAEW + + WP EG V F + RYR+ LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI EA +G I+IDG +I+++GLH LR +ITIIPQDP+LF+G+LR NLDP + +SD +IW +LE AHLK + L L+HE +EGGEN SVGQRQL+CLARALLRK+KILVLDEATAAVDL TD+LIQ+TI+ +FE CTV+TIAHRLNTI+D R+ V G++ E SP LL +M D+G
Sbjct: 13 EPFWDWNLTWHTENPDFTQCFQNTVLVWVPCIYLWVCFPAYFLY------LRSHDRGYIQMSILNKAKTALGLILWIVCWADLFYSFWERSQNIFR----APFFLISPTVLGITMLLATFLIQHERLKGVQSSGVMMIFWLISLLCATVIFRSKI--MLALNTDTEVDAFRYVTFCTYFILLLVQLILSCFPEKPPLFSE--AVNDPKPCPEFSASFLSRITFWWITGLMIQGHRRPLEAKDLWSLNKEDTSEEIVPGLAKNWAKEWAKTKRQPLNMLYSSKKQQKSSDSNGEVMEEAEALIIKPSQRSSEASLSKVLYKTFGPYFLMSFLFKAAHDLLMFTGPEILKLLINFVNNKSAPNWQGYFYTGLLFVCACLQTLILHQYFHICFVTGMRLKTAIVGVIYRKALVITNSARKTSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPSVLAGVAVMILLVPINAVMAMKTKTYQVAQMKSKDNRIKLMNEILNGIKVLKLYAWELAFREKVLEIRQKELKVLKKSAYLAAMGTFTWVCAPFLVALSTFAVYVKVNKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVEASVSLKRLRVFLSHEELDPDSIIRGPITNAEGSIVVKNATFSWSK-TDPPSLNSINFTVPEGSLIAVVGQVGCGKSSLLSALLGEMDKKEGYVVVKGSIAYVPQQAWIQNATLEDNIIFGREMNESRYKRVIEACALLPDLEILPMGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADTYLFDDPLSAVDAHVGKHIFEKVI-GPKGILKNKTRVLVTHAVNYLPQMDTILVMTDGEISEMGSYQELLKQDGAFAEFLRTYANAEQSMESSDASSPSGKEGKPVENGVLVNDATGKLMHRQLSNSSTYSRETGKSQHQSSTAELQKPLAEKNSWKLTEADTAKTGRVKATVYWEYMKAIGLYISFLSVFLFMCNHIASLASNYWLSLWTD------DPVVNGTQQYTNVRLGVYGALGISQGIAVFGYSMAVSIGGIFASRHLHLDLLHNVLRSPMSFFERTPSGNLVSRFSKEIDTIDSTIPPIIKMFMGSTFNVIGACIIILLATPIAAVVIPPLGLVYLLVQRFYVATSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQKRFIKQNDMKVDENQKAYYPSIVANRWLAVRLEFVGNCIVLFAALFAVIARNKLSPGLIGLSVSYSLQITAYLNWLVRMTSDLETNIVAVERVKEYAEMEKEAEWSIE-ETAPASTWPQEGKVEFRGFGLRYREDLDLVLKNINITINGGEKVGIVGRTGAGKSSLTLGLFRINEAAEGEIIIDGINIAKIGLHDLRFKITIIPQDPILFSGSLRMNLDPFDQHSDEDIWRSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDNLIQSTIKSQFEECTVLTIAHRLNTIMDYTRVLVLDRGEVVECDSPDNLL-QAKGLFYSMAKDSG 1523
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|52783101|sp|O35379.1|MRP1_MOUSE (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1147.5 bits (2967), Expect = 0.000e+0 Identity = 630/1536 (41.02%), Postives = 925/1536 (60.22%), Query Frame = 0
Query: 176 FCR----DPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEW--VLFLTYFPIVLVLFITQCWVDIRP-----SSAKHLALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQV---------------KD-------KLVDFTTTIRPFV----------SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKE-PTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNH-TLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTS--DPMSSDKD----------PDEPKVMLPDVIAE-------------TPDQQESTLVVELEKTSNGTKAD---LIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHP--DLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
FC DP +D N TW+T++P+ T C ++T+L +PC P++ Y +++ R + L L ++ + +L W S+ V P + + LG+ ++LA + ++ S + FWL LLC + L+ I S + + + F YF +VLV + C+ D P ++ E AS LS + F W+ G++ G+R+PL + L + + +N W+ + KD +D + + SL+ +L K G L+S + H L+ F P+IL+L+IN VN +E P WQG+FYT +L S+ + T+ H Y + VS ++++++++GAVYRK+L ++N ARK TVGE+ NLMSVDAQR +D + + + ++P +++ALYFL++ LG + L+G+AV +++P+N + + QV +++KD R+KL+NE+LNG+KVLKLYAWE F ++ IR E+KV++ A L A+ FT+ TP LV + F V+V +D ++L A+K F SL+LFN++R PL + P + V+ VS KR+ FL+ E++P ++ ++ N+I + NAT TW P L+ I SIP G+L A+VG VG GKSSLL++ L EM+K+ G V ++GS+AYVPQQAWIQN +L++NILF + Y V+ C L DL IL D TEIGE G+N SGGQKQRVSLARAVYS++DIYL DDPLSAVDAHVGK IF +V+ G LK+KTR+LVTH I++L ++D IIV+ GK++E GSYQ+LL AF+EFL Y + ++S+ D P E +++ D + + Q+ + + EL+K G K + L+E + A G+V+ VY NY+++IG + + ++ + ++Y LS W D D P + A+ + L +Y +G++ + AS+ +H LL ++RSPMSFF+ P G ++NRFS ++D +D IP + + F + ++II +TP A +IPPL ++Y+ +QRF++ +SRQ+KRLES+S+SP+++HF+ET+ G++ IRA+++Q+RF+H+S +V + + ++ ANRWL R+E +GN +V FAA+FAV+SR SLS G+ GLS++YSL I LNW++RM E+ETN VA+ER+ EY+ EA W + + WP G V F Y RYR+ LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+IDG +I+++GLH LR +ITIIPQDPVLF+G+LR NLDP YSD E+W ALE AHLKG + L L+HE EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TD+LIQ+TIR +FE CTV+TIAHRLNTI+D R+ V G++ E G+P+ELL +M DAG
Sbjct: 6 FCSADGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFFY--LSRHDRGYIQMTHLNKTKTALGFFLWIICWADLFYSFWERSQGV----LRAPVLLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAHVDVFRDSTFYLYFTLVLVQLVLSCFSDCSPLFSETVHDRNPCPESSASFLSRITFWWITGMMVHGYRQPLESSDLWSLNKEDTSEEVVPVLVNNWKKECDKSRKQPVRIVYAPPKDPSKPKGSSQLDVNEEVEALIVKSPHKDREPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPKILELIINFVNDREAPDWQGYFYTALLFVSACLQTLALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVKNATFTWARGE-PPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPM-GLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFLRTYANAEQDLASEDDSVSGSGKESKPVENGMLVTDTVGKHLQRHLSNSSSHSGDTSQQHSSIAELQKA--GAKEETWKLMEADKAQTGQVQLSVYWNYMKAIGLFITFLSIFLFLCNHVSALASNYWLSLWTD---DPPVVNGTQANRNFRLSVYGALGILQGAAIFGYSMAVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ-ETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQ-RGIFYSMAKDAG 1526
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|75072869|sp|Q864R9.1|MRP1_MACFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1145.95 bits (2963), Expect = 0.000e+0 Identity = 643/1550 (41.48%), Postives = 927/1550 (59.81%), Query Frame = 0
Query: 176 FCR----DPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPH---TVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMA----VSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHL-----ALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWR--------------------TQVKDK-LVDFTTTIRPFV----------SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVN-SKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNH--TLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVV------------------------------ELEKTSNGTKAD----LIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWAD-----YNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
FC DP +D N TW T++P+ T C ++T+LV +PC P + +Y +++ R + T+ K AL +L L +V + +L W S + L P + + LG+ ++LA + ++ S + FWL LLC + L+ I + + V R+ + F YF +VL+ + C+ D P ++ + E AS LS + F W+ GL+ G+R+PL + L + + W+ Q KD VD + + SL+ +L K G L+S H L+ F P+ILKLLIN VN +K P WQG+FYT +L ++ + T+ H Y + VS ++++++++GAVYRK+L ++N ARK TVGE+ NLMSVDAQR +D + + + ++P +++ALY L+ LG L+G+AV +++PVN + + QV +++KD R+KL+NE+LNG+KVLKLYAWE F ++ IR E+KV++ A L A+ FT+ TP LV + F VYV ID ++VL A+K F SL+LFN++R PL + P + V+ VS KR+ FL+ E++P ++ D N+I + NAT TW + P L+ I SIP G+L A+VG VG GKSSLL++ L EM+K+ G V ++GS+AYVPQQAWIQN +L++NILF + Y V++ C L DL IL D TEIGE G+N SGGQKQRVSLARAVY +ADIYL DDPLSAVDAHVGK IF V+ +G LK+KTR+LVTH++++L ++D IIV+ GK++E GSYQ+LLA AF+EFL Y S ++DP++ V + Q E+ ++V EL+K +G K + L+E + A G+VK VY +Y+++IG + + ++ ++Y LS W D Q+H T L +Y +G+ I + AS+ +H LL I+RSPMSFF+ P G ++NRFS ++D +D IP + + F+ + ++I +TP A +IPPL ++Y+ +QRF++ +SRQ+KRLES+S+SP+++HF+ET+ G++ IRA+++Q+RF+H+S +V + + ++ ANRWL R+E +GN +V FAA+FAV+SR SLS G+ GLS++YSL + LNW++RM E+ETN VA+ER+ EY+ EA W + + WP G V F +Y RYR+ LD VL+ I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+IDG +I+++GLH LR +ITIIPQDPVLF+G+LR NLDP YSD E+W++LE AHLKG + L LDHE EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQ+TIR +FE CTV+TIAHRLNTI+D R+ V G+I E+G+P++LL M DAG
Sbjct: 6 FCSADGSDPLWDWNVTWYTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLY--LSRHDRGYIQMTLLNKTKTALGFL---LWIVCWADLFYSFWERSRGIF----LAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEDVQVDLFRD--MTFYVYFSLVLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKDSSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPEILKLLINFVNDTKAPDWQGYFYTALLFVAACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPPILAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALCTFAVYVTIDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGDTNSITVRNATFTWAR-SDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVALKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVI-GPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYAS--AEQEQDPEDNGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDVSRQHNSTAELQK--DGAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFICNHVAALASNYWLSLWTDDPIVNGTQEH-------TKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSN-WPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQ-RGLFYNMARDAG 1529
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|85701143|sp|Q8CG09.2|MRP1_RAT (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1142.1 bits (2953), Expect = 0.000e+0 Identity = 630/1541 (40.88%), Postives = 927/1541 (60.16%), Query Frame = 0
Query: 176 FCR----DPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEW--VLFLTYFPIVLVLFITQCWVDIRPSSAKHL-----ALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQ-VKDK---------------------LVDFTTTIRPFV----------SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKE-PTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNH--TLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQY--TSDPMSSDKD-------------PDEPKVMLPDVIAE--------------TPDQQESTLVVELEKTSNGTKAD---LIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDL--ATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
FC DP +D N TW+T++P+ T C ++T+L +PC P++ +Y +++ R + A L L ++ + +L W S+ + L P + + LG+ ++LA + + S + FWL LLC + L+ I S + + + F YF +V + + C+ D P ++ + E AS LS + F W+ G++ G+R+PL + L + + +N W+ + VK + +D + + SL+ +L K G L+S + H L+ F P+IL+L+IN VN +E P WQG+ YT +L S+ + T+ H Y + V+ ++++++++GAVYRK+L ++N ARK TVGE+ NLMSVDAQR +D + + + ++P + +ALYFL++ LG + L+G+AV +++P N + + QV +++KD R+KL+NE+LNG+KVLKLYAWE F ++ +IR E+KV++ A L A+ FT+ TP LV + F V+V +D ++L A+K F SL+LFN++R PL + P + V+ VS KR+ FL+ E++P ++ D N+I + NAT TW D P L+ I +IP G+L A+VG VG GKSSLL++ L EM+K+ G V ++GS+AYVPQQAWIQN +L++NILF + Y V+ C L DL IL D TEIGE G+N SGGQKQRVSLARAVY ++DIYLLDDPLSAVDAHVGK IF +V+ G LK+KTR+LVTH I++L ++D IIV+ GK++E GSYQ+LL AF+EF+ Y T ++S+ D P E +++ D + + +QQ S+ EL+K+ G K + L+E + A G+VK VY NY+++IG + + ++ + ++Y LS W D D P + + + L +Y +G++ + + AS+ +H LL+ ++RSPMSFF+ P G ++NRFS ++D +D IP + + F + ++II +TP A +IPPL ++Y+ +QRF++ +SRQ+KRLES+S+SP+++HF+ET+ G++ IRA+++Q+RF+ +S +V + + ++ ANRWL R+E +GN +V FAA+FAV+SR SLS G+ GLS++YSL I LNW++RM E+ETN VA+ER+ EY+ EA W + + WP G V F Y RYR+ LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+IDG +I+++GLH LR +ITIIPQDPVLF+G+LR NLDP YSD E+W ALE AHLKG + L L+HE EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQ+TIR +FE TV+TIAHRLNTI+D R+ V G+I E G+P+ELL +M DAG
Sbjct: 6 FCSSDGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFLY--LSRHDRGYIQMTHLNKAKTALGFFLWIICWADLFYSFWERSQGM----LLAPVLLVSPTLLGITMLLATFLIQFERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAQVDMFRDSAFYLYFTLVFIQLVLSCFSDSSPLFSETVRDPNPCPESSASFLSRITFWWITGMMVQGYRQPLKSSDLWSLNKEDTSEEVVPVLVNNWKKECVKSRKQPVRIVYAPPKDPTKPKGSSQLDVNEEVEALIVKSSHKDRDPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPEILELIINFVNDREAPDWQGYLYTALLFVSACLQTLALHQYFHICFVTGMRIKTAVVGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMNSITVKNATFTWARDE-PPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPM-GLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFVRTYANTEQDLASEDDSKNGVSGLGKESKPVENGILVTDAVGKPLQRHLSNSSSHSVVTNQQHSS-TAELQKS--GVKEETWKLMEADKAQTGQVKLSVYWNYMKAIGLCISFLSIFLFLCNHVSALASNYWLSLWTD---DRPAVNGTQENRNFRLSVYGALGILQGVAVFGYSMAVSIGGIFASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEASWQIQ-ETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQ-RGVFYSMAKDAG 1530
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|75072999|sp|Q8HXQ5.1|MRP1_BOVIN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1136.32 bits (2938), Expect = 0.000e+0 Identity = 640/1542 (41.50%), Postives = 924/1542 (59.92%), Query Frame = 0
Query: 176 FCR----DPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEW--VLFLTYFPIVLVLFITQCWVDIRPSSAKHL-----ALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQV--------------KDKL-------VDFTTTIRPFV----------SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKE-PTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHT--LDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPD---------------EPKVMLPDVIAETPDQ-------------QESTLVVELEKTSNGTKA-DLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWAD-----YNQDHPDLATASTTYYLGIYAGIGLVG--MIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
FC D F++ N TWNT++P+ T C ++T+LV +PC+ + P + +Y + + R + A L L +V + +L W E G L P + + LG+ ++LA + ++ S + FWL LLC + L+ I + + + + V F YF +VL+ + C+ D P ++ + E AS LS + F W+ G++ G+R+PL T L + + W+ + KD VD + SL+ +L K G L+S + H L+ F P+ILKLLIN VN K+ P WQG+FYT +L S+ + T+ H Y + VS ++++++++GAVYRK+L ++N ARK TVGE+ NLMSVDAQR +D + + + ++P +++ALY L++ LG + L+G+AV +++P+N + + QV +++KD R+KL+NE+LNG+KVLKLYAWE F ++ IR E+KV++ A L A+ FT+ TP LV + F VYV +D +++L A+K F SL+LFN++R PL + P + V+ VS KR+ FL+ ++DP ++ D A N+I + NAT TW + P L I S+P GSL A+VG VG GKSSLL++ L EM+K+ G V V+GS+AYVPQQAWIQN++L++NILF ++ Y VV C L DL IL D TEIGE G+N SGGQKQRVSLARAVY D+D+YLLDDPLSAVDAHVGK IF V+ +G LK+KTR+LVTH I++L +MD IIV+ GK++E GSYQ+LLA AF+EFL Y S + D E +++ D + + Q T EL K + L+E + A G+VK VY +Y+++IG + + ++ +++Y LS W D Q+H + S LGI GI + G M +++ F AS+ +H LL ++RSP+SFF+ P G ++NRFS ++D +D IP + + F+ + +II +TP A +IPPL ++Y+ +QRF++ +SRQ+KRLES+S+SP+++HF+ET+ G++ IRA+++Q+RF+ +S +V + + ++ ANRWL R+E +GN +V FA++FAV+SR SLS G+ GLS++YSL + LNW++RM E+ETN VA+ER+ EY+ EA W + D WP G V F Y RYR+ LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+ID +I+++GLH LR +ITIIPQDPVLF+G+LR NLDP YSD E+W++LE AHLKG + L L+HE EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQ+TIR +F+ CTV+TIAHRLNTI+D R+ V G+I E+GSP++LL +M D+G
Sbjct: 6 FCSVDGSDLFWEWNVTWNTSNPDFTKCFQNTVLVWVPCSYLWVCFPFYFLY--LSHHDRGYIQMTHLNKAKTALGFLLWIVCWADLFYSFW---ERSMG-KLLAPVFLVSPTLLGITMLLATFLIQIERRRGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDARVDVFRDVTFYIYFSLVLIQLVLSCFSDRSPLFSETINDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSRKQPVKIVYSSKDPAKPKGSSKVDVNEEAEALIVKCPQKERDPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKDAGATNSITVKNATFTWARND-PPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVI-GPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQGQPEDGLAGVGGPGKEVKQMENGMLVTDTAGKQMQRQLSSSSSYSRDVSQHHTSTAELRKPGPTEETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQV-RLSVYGALGISQGITVFGYSMAVSIGGIF--------ASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ-DMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQ-RGLFYSMAKDSG 1528
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|296439301|sp|P33527.3|MRP1_HUMAN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1134.4 bits (2933), Expect = 0.000e+0 Identity = 636/1545 (41.17%), Postives = 926/1545 (59.94%), Query Frame = 0
Query: 176 FCR----DPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTP--KKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEW--VLFLTYFPIVLVLFITQCWVDIRPSSAKHL-----ALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQV---------------------KDKLVDFTTTIRPFV----------SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVN-SKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNH--TLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVV--------------------ELEKTSNGT----KADLIEEET--------ALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWAD-----YNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
FC DP +D N TWNT++P+ T C ++T+LV +PC P + +Y + +R +TP K AL +L L +V + +L W S + L P + + LG+ ++LA + ++ S + FWL L+C + L+ I + + + + + F YF ++L+ + C+ D P ++ + E AS LS + F W+ GL+ G+R+PL + L + + W+ + + VD + + SL+ +L K G L+S H L+ F PQILKLLI VN +K P WQG+FYT +L ++ + T+ H Y + VS ++++++++GAVYRK+L ++N ARK TVGE+ NLMSVDAQR +D + + + ++P +++ALY L++ LG + L+G+AV +++PVN + + QV +++KD R+KL+NE+LNG+KVLKLYAWE F ++ IR E+KV++ A L A+ FT+ TP LV + F VYV ID +++L A+ F SL+LFN++R PL + P + V+ VS KR+ FL+ E++P ++ D N+I + NAT TW + P L+ I SIP G+L A+VG VG GKSSLL++ L EM+K+ G V ++GS+AYVPQQAWIQN +L++NILF + Y V++ C L DL IL D TEIGE G+N SGGQKQRVSLARAVYS+ADIYL DDPLSAVDAHVGK IF V+ +G LK+KTR+LVTH++++L ++D IIV+ GK++E GSYQ+LLA AF+EFL Y S ++D +E V + Q E+ ++V ++ + N T KA+ +EET A G+VK VY +Y+++IG + + ++ + ++Y LS W D Q+H T L +Y +G+ I + AS+ +H LL I+RSPMSFF+ P G ++NRFS ++D +D IP + + F+ + ++I +TP A +IPPL ++Y+ +QRF++ +SRQ+KRLES+S+SP+++HF+ET+ G++ IRA+++Q+RF+H+S +V + + ++ ANRWL R+E +GN +V FAA+FAV+SR SLS G+ GLS++YSL + LNW++RM E+ETN VA+ER+ EY+ EA W + + WP G V F +Y RYR+ LD VL+ I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+IDG +I+++GLH LR +ITIIPQDPVLF+G+LR NLDP YSD E+W++LE AHLK + L LDHE EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQ+TIR +FE CTV+TIAHRLNTI+D R+ V G+I E+G+P++LL +M DAG
Sbjct: 6 FCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLS-RHDRGYIQMTPLNKTKTALGFL---LWIVCWADLFYSFWERSRGIF----LAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWAR-SDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVI-GPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYAS--TEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEH-------TKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ-ETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQ-RGLFYSMAKDAG 1529
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|218526606|sp|B2RX12.1|MRP3_MOUSE (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1133.63 bits (2931), Expect = 0.000e+0 Identity = 646/1534 (42.11%), Postives = 908/1534 (59.19%), Query Frame = 0
Query: 181 FFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLV-----------PSEIFHYSCL--GVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTRE--EWVLFLTYFPIVLVLFITQCWVDIRPS-SAKHL----ALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQVKDKLVDFTTTIRPFV-----------------SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHV-NSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSD-----KDPDEPKVMLPDVIAETPD----------------QQESTLVVE---------------LEKTSNGTKAD----LIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
F+D N + T P++TPC +++LL +PC + P ++ Y R H + L LK L ++ LWC S W L P+ +F + L G+ ++LA L + + S L +FWL ++C I + I S +A + + F YF +V I C+ + P S ++L E A S L F W L G+RRPL L + W+ Q T T P + S LV+ LL+S + +LL FVNPQ+L +LI + + PTW GF G++ SST+ T+ H Y + V A+++R++++G +YRK+L ++N +++ TVGEM NLMSVDAQR +D SP + L ++P +++A+YFL+ LG + L+G+AV +LIP+N S + QV Q++ KD R+KL++E+LNG+KVLKLYAWE F+ ++ IR +E+++++ A L A+ F + TP LVT++ VYV +D S+VL AEK F SLSLFN+++IPL M P + + VS KRI FLN NE+DP+ V AI + N T TW +D P L +N+ IP+G+L A+VG VG GKSSL+++ LGEMEKL G V V+GS+AYVPQQAWIQN TL++N+LF Q + +Y + + C L +DL +L D TEIGE GIN SGGQ+QRVSLARAVYSDA+I+LLDDPLSAVD+HV K IF QV+ EG L KTRVLVTH I+FL + D IIVL G+V+E G Y LL +F+ FL Y D D ++ +E ++L D ++ D ++ S+L E LEK + TK LI+EE A G VK VY +Y +S+G + I +Y + A+ LS W++ ++H T+ LG+YA +G++ ++ ++ F V +A++++HE LL +RSP SFFDT P GRI+NRFS DI ID+ + + L FF +++ I++I +STP F V+ PL +LY +QRF++ TSRQ+KRLES+S+SPIF+HFSETVTG + IRAY + F S +V ++ +++NRWLG VE +GN VV FAA+FAV+ R SL+PG+ GLS++Y+L + LNWMIRM+ +LE+N +A+ER+ EY+ EA W + + + WP G V F +Y+ RYR GL+LVLK + + V+ EK+GI GRTGAGKSS+TL LFRI+EA +G I+IDG +++ +GLH LRS++TIIPQDP+LF+G LR NLDP YS+ +IW ALE +HL + GLD + EGG+N SVGQRQL+CLARALLRK+++LVLDEATAA+DL TDDLIQ TIR +FE CTV+TIAHRLNTI+D +R+ V G +AEF SP L+A M DAG
Sbjct: 14 FWDSNLSIYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFY------LRHHQLGYIVLSWLSRLKTALGVL--------LWCVS-----WVDLFYSFHGLIHGSSPAPVFFVTPLVVGITMLLATLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSALAEGKILDPFRFTTFYIYFALVFCALILSCFKEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASGSQTATAEPKIPGEDAVLLKPRPKSKQPSFLRALVRTFTSSLLMSACFNLIQNLLGFVNPQLLSILIRFISDPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISPGY-AITIHNGTFTWAQDL-PPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVI-GPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLEDTLSTHTDLTDNEPAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTKETGALIKEEIAETGNVKLSVYWDYAKSMGLCTTLSICLLYGGQSAAAIGANVWLSAWSNDAEEHGQ--QNKTSVRLGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTEAPWVVESN-RAPEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAKDAG 1521
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|75071939|sp|Q6UR05.1|MRP1_CANFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1127.46 bits (2915), Expect = 0.000e+0 Identity = 637/1545 (41.23%), Postives = 923/1545 (59.74%), Query Frame = 0
Query: 176 FCR----DPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSK-LVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEW--VLFLTYFPIVLVLFITQCWVDIRPSSAKHL-----ALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQV--------------KD-------KLVDFTTTIRPFV----------SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKE-PTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNH--TLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPD---------------EPKVMLPDVIAETPDQQES-------------TLVVELEKTS--NGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWAD-----YNQDHPDLATASTTYYLGIYAGIGLVG--MIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDL-PLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
FC DPF++ + +WNT++P+ T C ++T+LV +PC + P + +Y +++ R + L L +V + +L W S W K L P + + LG+ ++LA + ++ S + FWL LLC + L+ I + + + + V F YF +VL+ + C+ D P ++ + E AS LS + F W+ GL+ G+R+PL T L + + W+ + KD VD + SL+ +L K G L+S + H L+ F P+ILKLLIN VN K+ P WQG+ YT +L + + T+ H Y + VS ++++++++GAVYRK+L ++N ARK TVGE+ NLMSVDAQR +D + + + ++P +++ALY L++ LG + L+G+AV +++P+N + + QV +++KD R+KL+NE+LNG+KVLKLYAWE F ++ IR E+KV++ A L A+ FT+ TP LV + F VYV +D +++L A+K F SL+LFN++R PL + P + V+ VS KR+ FL+ E++P ++ D N+I + NAT TW + P L I SIP GSL A+VG VG GKSSLL++ L EM+K+ G V ++GS+AYVPQQAWIQN +L++NILF ++ Y V+ C L DL IL D TEIGE G+N SGGQKQRVSLARAVY D+DIYL DDPLSAVDAHVGK IF V+ +G LK+KTR+LVTH+I++L ++D IIV+ GK++E GSYQ+LLA AF+EFL Y S + D E +++ DV + +Q S T EL+K N L+E + A G+VK VY +Y+++IG + + ++ +++Y LS W D Q+H + S LGI GI + G M +++ F AS+ +H LL+ ++RSPMSFF+ P G ++NRFS ++D +D IP + + F+ + +II +TP + +IPPL ++Y+ +QRF++ +SRQ+KRLES+S+SP+++HF+ET+ G++ IRA+++Q+RF+ +S +V + + ++ ANRWL R+E +GN +V FAA+F+V+SR SLS G+ GLS++YSL + LNW++RM E+ETN VA+ER+ EY+ EA W + + P WP G V F Y RYR+ LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+ID +I+++GLH LR +ITIIPQDPVLF+G+LR NLDP YSD E+W++LE AHLK + GL L+ E EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQ+TIR +F+ CTV+TIAHRLNTI+D R+ V G+I E G P++LL +M DAG
Sbjct: 6 FCSADGSDPFWEWDVSWNTSNPDFTKCFQNTVLVWVPCCYLWLCFPFYFLY--LSRHDRGYIQMTYLNKTKTALGFVLWIVCWADLFYSFWERS-----WGKILAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDAEIDVFRDVTFYIYFSLVLIQLVLSCFSDRPPLFSETIHDLNPCPESSASFLSRVTFWWITGLMVRGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQRKITYSSKDPAKPKGGSQVDVNEEAEVLIVKTPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDKKAPDWQGYLYTALLFICACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGANSITVKNATFTWAR-SDPPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVI-GPKGMLKNKTRLLVTHSISYLPQVDVIIVMTGGKISEMGSYQELLARDGAFAEFLRTYASGDQEQAEQDDGLTGVSSPGKEVKQMENGMLVTDVAGKQLQRQLSNSSSYSGDVSRHHTSTAELQKAGPKNEDAWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTKIRL-SVYGALGISQGITVFGYSMAVSIGGIF--------ASRRLHVDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIASIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFSVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQEMAPP--STWPQVGRVEFRDYGLRYRENLDLVLKHINITINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRVKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGQPSDLLQQ-RGLFYSMAKDAG 1529
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|6016599|sp|O88563.1|MRP3_RAT (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=MRP-like protein 2; Short=MLP-2; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1104.74 bits (2856), Expect = 0.000e+0 Identity = 626/1533 (40.83%), Postives = 887/1533 (57.86%), Query Frame = 0
Query: 181 FFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLV-----------PSEIFHYSCL--GVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTRE--EWVLFLTYFPIVLVLFITQCWVDIRPS-SAKHL----ALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQVKDKLVDFTTTIRPFV-----------------SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKD-----PDEPKVMLPDVIAETPDQQE-----------------------------------STLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
F+D N T T P++TPC +++LL +PC + P ++ Y R H + L LK L ++ LWC S W L P+ +F + L G+ ++LA L + + S L +FWL ++C I + I +A + + F YF +VL FI C+ + P S ++L E A S L F W L G+RRPL + L + W+ Q T + P + S LV+ LL+ + L P P W GF G++ SST+ T+ H + + V A+++R++++G +YRK+L ++N +++YTVGEM NLMSVDAQR +D SP + L ++P +++A+YFL+ LG + L+G+AV +LIP+N S + QV Q++ KD R+KL++E+LNG+KVLKLYAWE F+ ++ IR E+++++ A L A+ F + TP +VT++ VYV +D ++VL AEK F SLSLFN+++IPL + P + + VS KRI FLN +E+DP+ V + AI + N T +W +D P L IN+ IP+G+L A+VG VG GKSSL+++ LGEMEKL G V V+GS+AYVPQQAWIQN TL++N+LF Q + +Y + + C L +DL +L D TEIGE GIN SGGQ+QRVSLARAVYSDA+I+LLDDPLSAVD+HV K IF QV+ EG L KTRVLVTH I+FL + D IIVL +G++ E G Y +LL +F+ FL Y D + +E ++L D ++ D + S+L E+ T LI+EE A G VK VY +Y +S+G +FI +YA A+ LS W + ++H +T+ LG+YA +G++ ++ ++ F V +A++++H LL +R+P SFFDT P GRI+NRFS DI I + + + F+ +++ IV+I +STP F V+ PL + Y +QRF++ TSRQ+KRLES+S+SPIF+HFSETVTG + IRAY + F S A+V T+ +++NRWLG VE +GN VV F+A+FAV+ R SL+PG+ GLS++Y+L + +LNWMIR L +LE+N +A+ER+ EY+ EA W L + + WP G V F +Y+ RYR GL+LVLK + + V+ EK+GI GRTGAGKSS+TL LFRI+EA +G I IDG +++ +GLH LRS++TIIPQDP+LF+G LR NLDP YSD +IW LE +HL + GLD + +EGG+N SVGQRQL+CLARALLRK+++LVLDEATAA+DL TDDLIQ TIR +FE CTV+TIAHRLNTI+D +R+ V G +AEF SP L+A M DAG
Sbjct: 14 FWDSNLTVYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFY------LRHHRLGYIVLSCLSRLKTALGVL--------LWCIS-----WVDLFYSFHGLVHGSSPAPVFFITPLLVGITMLLATLLIQYERLRGVRSSGVLIIFWLLCVICAIIPFRSKILLALAEGKILDPFRFTTFYIYFALVLCAFILSCFQEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTKLAILGYRRPLEDSDLWSLSEEDCSHKVVQRLLEAWQKQQTQASGPQTAALEPKIAGEDEVLLKARPKTKKPSFLRALVRTFTSSLLMGACFKLIQDLSPSSTHSCSASSSGLFRPHGPYWWGFLLAGLMFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDELDPQCVERKTISPGR-AITIHNGTFSWSKDL-PPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVI-GPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTEPAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKSVGLCTTLFICLLYAGQNAVAIGANVWLSAWTNDVEEHGQ--QNNTSVRLGVYATLGILQGLLVMLSAFTMVVGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNCVVLFSALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSKTETEAPWVLESN-RAPEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAKDAG 1520
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|6920069|sp|O15438.3|MRP3_HUMAN (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multi-specific organic anion transporter D; Short=MOAT-D; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1085.48 bits (2806), Expect = 0.000e+0 Identity = 631/1544 (40.87%), Postives = 902/1544 (58.42%), Query Frame = 0
Query: 181 FFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKL-----------VPSEIFHYSCL--GVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEWVLFLTY---FPIVLVLFITQCWVDIRPS-SAKHLAL----EDKASCLSLLLFSWMDGLLWDGFRRPLT----WTRLPQFPRSMNVTDNTATFMNQWRTQVK-----------------DKLVDFTTTIRPFV-SLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHV-NSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDP---------MSSDKDPDEPKVMLPDVIA---ETPDQQESTLVVELE-------KTSNG----------------------TKAD--LIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLD-PKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
F+D N + +T +P++TPC +++LL +PC ++ P +++Y R H C L L + + +L LWC S W+ L P+ +F + L GV ++LA L + + S L +FW ++C I + I L G + F T+ F +VL I C+ + P SAK++ E A LS L F W + G+R PL W+ L + RS V + WR Q K + V RP S L+ G LIS + LL F+NPQ+L +LI + N P+W GF G++ S + ++ Y + V+ ++ R+ ++G +YRK+L ++N ++ TVGE+ NLMSVDAQR +D +P + L ++P I++A+YFL+ LG + L+G+A +LIP+N + QV Q++ KD R+KL++E+LNG+KVLKLYAWE F++++ IR E+++++ A L FT+ +P LVT++ VYV +DP++VL AEK F S+SLFN++R+PL M P + + VS KRI +FL+ E+DP++V AI + + T TW +D P L +++ +P+G+L A+VG VG GKSSL+++ LGEMEKL G+V ++GS+AYVPQQAWIQN TL++N+LF + + +Y + + C L +DL +L D TEIGE GIN SGGQ+QRVSLARAVYSDADI+LLDDPLSAVD+HV K IF V+ EG L KTRVLVTH I+FL + D IIVL +G+V+E G Y LL +F+ FL Y D + + D+ +++ D ++ + D T VV+ + +S+G KAD L +EE A +G V+ V+ +Y +++G + I +Y + A+ LS W N D +T+ LG+YA +G++ + ++ +A++V+H+ LL +RSP SFFDT P GRI+N FS DI +D+ + + L FF+ ++ +V+I +STP F VI PL +LY ++QRF+ TSRQ+KRLES+S+SPI++HFSETVTG + IRAY + F S +V + + +NRWL VE +GN VV FAA+FAV+ R SL+PG+ GLS++YSL + LNWMIRM+ +LE+N VA+ER+ EY+ EA W + P G WP G V F +Y+ RYR GLDLVL+ + + V EK+GI GRTGAGKSS+TL LFRI+EA KG I IDG +++ +GLH LRS++TIIPQDP+LF+G LR NLDP YS+ +IW ALE +HL + GLD + +EGGEN SVGQRQL+CLARALLRK++ILVLDEATAA+DL TD+LIQ TIR +F+ CTV+TIAHRLNTI+D R+ V G +AEF SPA L+A M DAG
Sbjct: 14 FWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLY------LRHH------CRGYIILSHLSKLKMVLGVL--LWCVS-----WADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKIL-LAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWS-LKEEDRSQMVVQQ---LLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGY-AITIHSGTFTWAQDL-PPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVI-GPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYAPDEDQGHLEDSWTALEGAEDKEALLIEDTLSNHTDLTDNDPVTYVVQKQFMRQLSALSSDGEGQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWT--NDAMADSRQNNTSLRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRPPEG--WPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIA-ARGIFYGMARDAG 1525
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|586962516|gb|AHK05646.1| (ATP-binding cassette transporter sub-family C member 1 isoform X6 [Tigriopus japonicus]) HSP 1 Score: 1906.34 bits (4937), Expect = 0.000e+0 Identity = 922/1465 (62.94%), Postives = 1145/1465 (78.16%), Query Frame = 0
Query: 174 DPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQSLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLALEDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQVKDKLVDFTT-TIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPK-VGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+ FCRDPFFD+N WNTTDPN+T C++DTLL+G+PC LI+S IW +YQ + R ++ + GALF+ K+ L L++ VN +GQLW + GGW +LVPSEI HY+CL + +A +Q+ +D +L +H SPPLFLFWL L+ CE+ KLKIDIQ+++ T E WVL L+YFP++ V + C DI ++A ++ ED+AS LSLL FSW DGL+W G R+ LT LP+ PRS+NV N F+N WR +V+ V+F + RPF+ +W I ++ R+ + ++AI H +LPFVNPQILKLLINHV+S E W+G+FYT +LL S+TVSTITFHVYQQ LS+SAIQMRS+++GA+YRKSLKLSN AR+Q+TVGE+TN MSVDAQR+VD P M+LI +P TI++A+YFL++E+G++ L+GLA+ ILIP+N G KWAE LQV QL+AKDKRLKL+NEVL GM+VLKLYAWE PFM RI IR +E+K+++LCARLWA MNFTF+ PILVTI VF +YV IDPSHVLTA+KIF SLSLFNL+RIPLVMFPFTLVE +K++VS KRIN +LNANEI+ NV+H +D +A+EL + TLTWDE P L I++ IP+GSL A+VG VG+GKSSLL++ LGEME +SG GSIAYVPQQAWIQNM+LKDNILFD+ + ++YD+VVR CQLESDLAILK+ D TEIGENGIN SGGQKQRVSLARAVYSDAD+YLLDDPLSAVDAHVGK+IFTQV D+ +G KDKTR+LVTHNI+ L K+DNIIV+K G+V E GSYQKLLADG AFSEFL Y + + D+ + + +Q+ + +++ ++ DLI++E A+VG+VKW VY +YV S F +V ++A+G+ A ++Y LS WAD NQ+ PD A Y+LGIY G+V +I+ RE ++F+ CA ASQ++HEKLL + RSPMSFFDTNP GRIINRFSSD+D +DQ+IP GLSDT+W FD+++I+V+IC STP+F YVI PL +LYY IQR FI+TSRQ+KRLES+SKSPI+A+FSET+TG ASIRAY +Q RF ES+ RVQKCA CTFL SANRWLGTRVE+LGNL+VFFAAIFA+L+R++LSPG+AGLSITY+LNIMD LNW+IRMLCELETNSVALERI+EYTHN EA+W+ P D K + WP G V F+S A RYR GLDLVLKGI ME++ EKIGICGRTGAGKSS TL+LFRI+EA G I IDGQDIS++GLH LRSRITIIPQDPVLFTG+LRFNLDP ++SD +WSALEHAHLK HI K GLDHEINEGGENFSVGQRQLICLARALLRKTKIL++DEATAAVDL TDDLIQ TIRREF+ CTVITIAHRLNTI+DCDRIAVF+ G++AE+ P +LL+ +SAL M DAG
Sbjct: 14 ETFCRDPFFDVNTVWNTTDPNLTQCMQDTLLIGLPCCVLLITSVIWNLYQYVIEFRHVTSLEERSFGALFFAKLVLNLILIVNAVGQLWNLANLNGGWDQLVPSEIVHYACLLGILFVANVQVIIDKWLLSHTSPPLFLFWLVLIFCEVAKLKIDIQTIVEGHSTWEHWVLLLSYFPVIFVQLVLSCISDIDKTTALFVSPEDRASFLSLLTFSWFDGLIWKGARQILTQDILPKSPRSINVGHNVQDFLNLWRQKVEFLGVNFASFQERPFIGIWSIFIRTQWVRVTFAFLVAIIHLVLPFVNPQILKLLINHVDSDEEAWKGYFYTVVLLISATVSTITFHVYQQHLSISAIQMRSAIIGAIYRKSLKLSNHARRQFTVGEITNYMSVDAQRVVDTFPYTMALIMAPLTIIVAMYFLFLEVGISSLAGLAILLILIPINGIGGKWAERLQVNQLKAKDKRLKLMNEVLMGMRVLKLYAWENPFMDRIKKIRDSEVKILRLCARLWAFMNFTFTGAPILVTIAVFALYVLIDPSHVLTADKIFVSLSLFNLIRIPLVMFPFTLVETIKLIVSLKRINTYLNANEINSANVSHNMD-CESDAVELKDLTLTWDEPES-PSLMNISIQIPKGSLVAVVGEVGSGKSSLLSAILGEMEVVSGSAHAVGSIAYVPQQAWIQNMSLKDNILFDKAFVRTKYDEVVRCCQLESDLAILKNADSTEIGENGINLSGGQKQRVSLARAVYSDADLYLLDDPLSAVDAHVGKSIFTQVFDNQQGLFKDKTRILVTHNISVLSKVDNIIVMKGGRVVEIGSYQKLLADGAAFSEFLNIYAQEATEKHEPVDDVNQFENSHVEQISEQK----INQIQDSTLAESGDLIKDERAMVGRVKWSVYWHYVNSSRISRFFLVVCLHAIGSALLASSNYWLSIWADANQNDPDEANTQIAYFLGIYGAFGVVQLILEFSRELMYFLGCATASQIMHEKLLYHVFRSPMSFFDTNPTGRIINRFSSDVDVVDQRIPQGLSDTMWSIFDSLSIVVVICVSTPSFGYVILPLVLLYYFIQRMFISTSRQVKRLESLSKSPIYANFSETITGTASIRAYGEQIRFNQESENRVQKCAQCTFLIASANRWLGTRVEILGNLIVFFAAIFAILARDTLSPGVAGLSITYALNIMDNLNWLIRMLCELETNSVALERIIEYTHNDQEADWESPNDSKELSQTWPNRGKVEFDSLAIRYRKGLDLVLKGISMEIQGQEKIGICGRTGAGKSSFTLALFRILEADSGEIRIDGQDISKIGLHALRSRITIIPQDPVLFTGDLRFNLDPTGLHSDSSLWSALEHAHLKSHISSFKDGLDHEINEGGENFSVGQRQLICLARALLRKTKILIMDEATAAVDLATDDLIQATIRREFKDCTVITIAHRLNTIMDCDRIAVFNQGEVAEYAPPRDLLSIDNSALSLMAKDAG 1472
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|642933793|ref|XP_008197317.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X4 [Tribolium castaneum]) HSP 1 Score: 1265.37 bits (3273), Expect = 0.000e+0 Identity = 697/1541 (45.23%), Postives = 963/1541 (62.49%), Query Frame = 0
Query: 170 STSEDPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAH-------ISPPLFLFWLHLLLCEIPKLKIDIQ-SLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLAL-----EDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWR--------------TQVKDKL----VDF-TTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQY--------------------TSDPMSSDKDPDEPKVMLPDVIAETPDQQES-------------------TLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWA--DYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSR-ESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+++ D FC F++ TW+T DP++T C T+LV +PCA S + + Y ++ R P L K+ T V+FV ++ V + SE Y ++ LL G+ L + S FLFWL L +C + + +++ S + +R ++ +L Y+P+VLV+ C+ D P +++ L E+ +S LS LLFSW D L W GFRRPL + L + ++ TF W+ T+ KL VD ++ + S+ P LVK G + ++ + LL FV+P IL LLI V + E W+GF Y G L ++T+ TI Y + V +++R++L+ A+Y+K+L++SNKARK+ TVGE+ NLMSVDAQ+ +D + + + ++P I++ALYFL+ LG A L+GLAV ILIPVN + + + LQ+ Q++ KD+R+KL+NEVL+G+KVLKLYAWE F ++I IR EI+V++ A + A +F +S P LV++V F YV +D ++L A K F S+SLFN++R PL M P + V+ +VS +RINKF+NA E+DP +V H +++A IE N WDE+ +L IN+ I + SL A+VG+VG+GKSSLL++FLGEM+K SG+V G+IAYV QQAWIQN TL+DNILF + + S YDKVV C L D A+L D TEIGE GIN SGGQKQRVSLARAVY+++DIY LDDPLSAVD+HVGK IF +V+ EG L+ KTRVLVTH I +L + D IIVLK+G+V+E G+YQ+LL AFSEFL+Q+ T+ +K + + + ++ET Q S + VE K G K LIE E A G VKW VY +Y++SIG L V + + L G ++ L WA D T +YLGIY +G+ I++L + + C AS +H+ +L+ ++R+PM FFDT P+GRI+ RFS D++ +D +P+G++D ++C F+ + +V+I STP F VI P+ ILYY IQRF++ TSRQ+KRLES+S+SPI++HF ET+TG+ +IRA+++QDRF+ ES+ RV C + ++ +NRWL R+E++GNL++FFAA+F+VL R ES + G+ GLS+TYSL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G V F YA RYR GLDLVLKG++ + EK+GI GRTGAGKSSLTL+LFRIIEA +G ILIDG +I+ LGLHTLRSR+TIIPQD VLF+G LR NLDP + +SD E+W ALEHAHLK + GL GL HE+ EGGEN SVGQRQLICL+RALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V +G+I EF SP+ LL S +M DAG
Sbjct: 3 ASTMDKFCGSEFWNSTLTWHTNDPDLTKCFERTVLVWVPCAFLWTFSSLEVYYILHSKRRD----IP--WNWLNVSKLLGTAVLFV------LTVTDLVTAVNSASSSESDVYKVDIYTPVIKLLSFGLSAVLLVYNRKYGLCTSGLQFLFWLSLAICGAFQYRTELRGSQEEIPESRYSYISYLIYYPVVLVMLFLNCFADRSPRRSEYPKLKNPCPEENSSFLSRLLFSWFDPLAWRGFRRPLVDSDLWDMKPEDSASEVVPTFEKHWKRILQKCESNSPTRQTRASYKLDSARVDIVNSSTKKQASILPALVKAFGPTFIFGALLKLIQDLLTFVSPHILNLLIQFVKNNEEQWKGFLYAGALFVTATIQTIVLSQYFNRMFVVGMRIRTALVSAIYKKALRVSNKARKESTVGEIVNLMSVDAQKFIDLTAYINMIWSAPLQIILALYFLWNILGPAVLAGLAVMIILIPVNGYIANKVKVLQIKQMKNKDERVKLMNEVLSGIKVLKLYAWEPSFEKQILKIRTKEIQVLKEAAYMNAGTSFIWSCAPFLVSLVSFGTYVMVDEHNILDASKAFVSVSLFNILRFPLSMLPMMISNLVQAMVSIQRINKFMNAEELDPTSVTHDSNESAPLVIE--NGCFNWDEEQ---VLKNINIRIEKKSLCAVVGSVGSGKSSLLSAFLGEMDKTSGRVNTVGTIAYVSQQAWIQNATLRDNILFGKSFDKSLYDKVVEACALNPDFAMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYANSDIYFLDDPLSAVDSHVGKHIFDKVI-GPEGLLRHKTRVLVTHGITYLPQTDKIIVLKDGEVSEGGTYQELLDKKGAFSEFLLQHINEVEEDEEELDVLKSQLSGTAVSEEINKKLSRHRSRVSESVSETGSDQTSLSLQRQKSVESADKSLRHRSSSVEEAKKVKGEK--LIEVEKAETGSVKWIVYKHYLKSIGVFLTVATILLNMLFQGFSIGSNVWLGVWADDDTVVVDNVTDTGKRDFYLGIYGALGIGQAIMSLFADLAPQLGCCYASIALHQVMLRGVLRAPMLFFDTTPLGRILGRFSRDVETMDSSLPWGMTDGVYCLFEVLGTLVVISVSTPIFIAVIVPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETITGVQAIRAFREQDRFIKESEHRVDVNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFSVLGRDESQNAGLVGLSVTYSLQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKAPSPQWPENGTVQFNKYAVRYRPGLDLVLKGVNFSINGGEKVGIVGRTGAGKSSLTLALFRIIEAAEGEILIDGVNIADLGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWKALEHAHLKSFVKGLTAGLHHEVTEGGENLSVGQRQLICLSRALLRKTKVLILDEATAAVDLETDDLIQKTIRSEFKNCTVLTIAHRLNTIMDSDRVVVLDNGRIVEFDSPSNLLKQQQSIFYSMCKDAG 1522
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|642933797|ref|XP_008197328.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X6 [Tribolium castaneum]) HSP 1 Score: 1256.89 bits (3251), Expect = 0.000e+0 Identity = 693/1523 (45.50%), Postives = 949/1523 (62.31%), Query Frame = 0
Query: 170 STSEDPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAH-------ISPPLFLFWLHLLLCEIPKLKIDIQ-SLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLAL-----EDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWRTQVKDKLVDFTTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQY--------------------TSDPMSSDKDPDEPKVMLPDVIAETPDQQES-------------------TLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWA--DYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSP-MSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSR-ESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+++ D FC F++ TW+T DP++T C T+LV +PCA S + + Y ++ R P L K+ T V+FV ++ V + SE Y ++ LL G+ L + S FLFWL L +C + + +++ S + +R ++ +L Y+P+VLV+ C+ D P +++ L E+ +S LS LLFSW D L W GFRRPL + L + ++ TF W K L ++ + S+ P LVK G + ++ + LL FV+P IL LLI V + E W+GF Y G L ++T+ TI Y + V +++R++L+ A+Y+K+L++SNKARK+ TVGE+ NLMSVDAQ+ +D + + + ++P I++ALYFL+ LG A L+GLAV ILIPVN + + + LQ+ Q++ KD+R+KL+NEVL+G+KVLKLYAWE F ++I IR EI+V++ A + A +F +S P LV++V F YV +D ++L A K F S+SLFN++R PL M P + V+ +VS +RINKF+NA E+DP +V H +++A IE N WDE+ +L IN+ I + SL A+VG+VG+GKSSLL++FLGEM+K SG+V G+IAYV QQAWIQN TL+DNILF + + S YDKVV C L D A+L D TEIGE GIN SGGQKQRVSLARAVY+++DIY LDDPLSAVD+HVGK IF +V+ EG L+ KTRVLVTH I +L + D IIVLK+G+V+E G+YQ+LL AFSEFL+Q+ T+ +K + + + ++ET Q S + VE K G K LIE E A G VKW VY +Y++SIG L V + + L G ++ L WA D T +YLGIY +G+ + L+ ++ +Q++H LL I+R P +FFD P+GRI+NRFS D+D +D +P L + CFF + +V+I STP F VI P+ ILYY IQRF++ TSRQ+KRLES+S+SPI++HF ET+TG+ +IRA+++QDRF+ ES+ RV C + ++ +NRWL R+E++GNL++FFAA+F+VL R ES + G+ GLS+TYSL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G V F YA RYR GLDLVLKG++ + EK+GI GRTGAGKSSLTL+LFRIIEA +G ILIDG +I+ LGLHTLRSR+TIIPQD VLF+G LR NLDP + +SD E+W ALEHAHLK + GL GL HE+ EGGEN SVGQRQLICL+RALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V +G+I EF SP+ LL S +M DAG
Sbjct: 3 ASTMDKFCGSEFWNSTLTWHTNDPDLTKCFERTVLVWVPCAFLWTFSSLEVYYILHSKRRD----IP--WNWLNVSKLLGTAVLFV------LTVTDLVTAVNSASSSESDVYKVDIYTPVIKLLSFGLSAVLLVYNRKYGLCTSGLQFLFWLSLAICGAFQYRTELRGSQEEIPESRYSYISYLIYYPVVLVMLFLNCFADRSPRRSEYPKLKNPCPEENSSFLSRLLFSWFDPLAWRGFRRPLVDSDLWDMKPEDSASEVVPTFEKHW----KRILQKCESSTKKQASILPALVKAFGPTFIFGALLKLIQDLLTFVSPHILNLLIQFVKNNEEQWKGFLYAGALFVTATIQTIVLSQYFNRMFVVGMRIRTALVSAIYKKALRVSNKARKESTVGEIVNLMSVDAQKFIDLTAYINMIWSAPLQIILALYFLWNILGPAVLAGLAVMIILIPVNGYIANKVKVLQIKQMKNKDERVKLMNEVLSGIKVLKLYAWEPSFEKQILKIRTKEIQVLKEAAYMNAGTSFIWSCAPFLVSLVSFGTYVMVDEHNILDASKAFVSVSLFNILRFPLSMLPMMISNLVQAMVSIQRINKFMNAEELDPTSVTHDSNESAPLVIE--NGCFNWDEEQ---VLKNINIRIEKKSLCAVVGSVGSGKSSLLSAFLGEMDKTSGRVNTVGTIAYVSQQAWIQNATLRDNILFGKSFDKSLYDKVVEACALNPDFAMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYANSDIYFLDDPLSAVDSHVGKHIFDKVI-GPEGLLRHKTRVLVTHGITYLPQTDKIIVLKDGEVSEGGTYQELLDKKGAFSEFLLQHINEVEEDEEELDVLKSQLSGTAVSEEINKKLSRHRSRVSESVSETGSDQTSLSLQRQKSVESADKSLRHRSSSVEEAKKVKGEK--LIEVEKAETGSVKWIVYKHYLKSIGVFLTVATILLNMLFQGFSIGSNVWLGVWADDDTVVVDNVTDTGKRDFYLGIYGALGIGQAVATLLSALSLYIGAVNGAQLLHHLLLSNILRVPCTTFFDVTPVGRILNRFSKDVDTLDNILPMTLRGWITCFFSVLGTLVVISVSTPIFIAVIVPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETITGVQAIRAFREQDRFIKESEHRVDVNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFSVLGRDESQNAGLVGLSVTYSLQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKAPSPQWPENGTVQFNKYAVRYRPGLDLVLKGVNFSINGGEKVGIVGRTGAGKSSLTLALFRIIEAAEGEILIDGVNIADLGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWKALEHAHLKSFVKGLTAGLHHEVTEGGENLSVGQRQLICLSRALLRKTKVLILDEATAAVDLETDDLIQKTIRSEFKNCTVLTIAHRLNTIMDSDRVVVLDNGRIVEFDSPSNLLKQQQSIFYSMCKDAG 1500
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|642933791|ref|XP_008197311.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X2 [Tribolium castaneum]) HSP 1 Score: 1255.74 bits (3248), Expect = 0.000e+0 Identity = 695/1542 (45.07%), Postives = 959/1542 (62.19%), Query Frame = 0
Query: 170 STSEDPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAH-------ISPPLFLFWLHLLLCEIPKLKIDIQ-SLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLAL-----EDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWR--------------TQVKDKL----VDF-TTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQY--------------------TSDPMSSDKDPDEPKVMLPDVIAETPDQQES-------------------TLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWA--DYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSP-MSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSR-ESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+++ D FC F++ TW+T DP++T C T+LV +PCA S + + Y ++ R P L K+ T V+FV ++ V + SE Y ++ LL G+ L + S FLFWL L +C + + +++ S + +R ++ +L Y+P+VLV+ C+ D P +++ L E+ +S LS LLFSW D L W GFRRPL + L + ++ TF W+ T+ KL VD ++ + S+ P LVK G + ++ + LL FV+P IL LLI V + E W+GF Y G L ++T+ TI Y + V +++R++L+ A+Y+K+L++SNKARK+ TVGE+ NLMSVDAQ+ +D + + + ++P I++ALYFL+ LG A L+GLAV ILIPVN + + + LQ+ Q++ KD+R+KL+NEVL+G+KVLKLYAWE F ++I IR EI+V++ A + A +F +S P LV+++ F V+V ID +++LT E +F S++LF +MR+P+ + P +V CV+ +VS +RINKF+NA E+DP +V H +++A IE N WDE+ +L IN+ I + SL A+VG+VG+GKSSLL++FLGEM+K SG+V G+IAYV QQAWIQN TL+DNILF + + S YDKVV C L D A+L D TEIGE GIN SGGQKQRVSLARAVY+++DIY LDDPLSAVD+HVGK IF +V+ EG L+ KTRVLVTH I +L + D IIVLK+G+V+E G+YQ+LL AFSEFL+Q+ T+ +K + + + ++ET Q S + VE K G K LIE E A G VKW VY +Y++SIG L V + + L G ++ L WA D T +YLGIY +G+ + L+ ++ +Q++H LL I+R P +FFD P+GRI+NRFS D+D +D +P L + CFF + +V+I STP F VI P+ ILYY IQRF++ TSRQ+KRLES+S+SPI++HF ET+TG+ +IRA+++QDRF+ ES+ RV C + ++ +NRWL R+E++GNL++FFAA+F+VL R ES + G+ GLS+TYSL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G V F YA RYR GLDLVLKG++ + EK+GI GRTGAGKSSLTL+LFRIIEA +G ILIDG +I+ LGLHTLRSR+TIIPQD VLF+G LR NLDP + +SD E+W ALEHAHLK + GL GL HE+ EGGEN SVGQRQLICL+RALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V +G+I EF SP+ LL S +M DAG
Sbjct: 3 ASTMDKFCGSEFWNSTLTWHTNDPDLTKCFERTVLVWVPCAFLWTFSSLEVYYILHSKRRD----IP--WNWLNVSKLLGTAVLFV------LTVTDLVTAVNSASSSESDVYKVDIYTPVIKLLSFGLSAVLLVYNRKYGLCTSGLQFLFWLSLAICGAFQYRTELRGSQEEIPESRYSYISYLIYYPVVLVMLFLNCFADRSPRRSEYPKLKNPCPEENSSFLSRLLFSWFDPLAWRGFRRPLVDSDLWDMKPEDSASEVVPTFEKHWKRILQKCESNSPTRQTRASYKLDSARVDIVNSSTKKQASILPALVKAFGPTFIFGALLKLIQDLLTFVSPHILNLLIQFVKNNEEQWKGFLYAGALFVTATIQTIVLSQYFNRMFVVGMRIRTALVSAIYKKALRVSNKARKESTVGEIVNLMSVDAQKFIDLTAYINMIWSAPLQIILALYFLWNILGPAVLAGLAVMIILIPVNGYIANKVKVLQIKQMKNKDERVKLMNEVLSGIKVLKLYAWEPSFEKQILKIRTKEIQVLKEAAYMNAGTSFIWSCAPFLVSLITFAVFVYIDSNNILTHEVVFVSITLFGIMRLPMSLLPMLIVYCVEAMVSIQRINKFMNAEELDPTSVTHDSNESAPLVIE--NGCFNWDEEQ---VLKNINIRIEKKSLCAVVGSVGSGKSSLLSAFLGEMDKTSGRVNTVGTIAYVSQQAWIQNATLRDNILFGKSFDKSLYDKVVEACALNPDFAMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYANSDIYFLDDPLSAVDSHVGKHIFDKVI-GPEGLLRHKTRVLVTHGITYLPQTDKIIVLKDGEVSEGGTYQELLDKKGAFSEFLLQHINEVEEDEEELDVLKSQLSGTAVSEEINKKLSRHRSRVSESVSETGSDQTSLSLQRQKSVESADKSLRHRSSSVEEAKKVKGEK--LIEVEKAETGSVKWIVYKHYLKSIGVFLTVATILLNMLFQGFSIGSNVWLGVWADDDTVVVDNVTDTGKRDFYLGIYGALGIGQAVATLLSALSLYIGAVNGAQLLHHLLLSNILRVPCTTFFDVTPVGRILNRFSKDVDTLDNILPMTLRGWITCFFSVLGTLVVISVSTPIFIAVIVPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETITGVQAIRAFREQDRFIKESEHRVDVNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFSVLGRDESQNAGLVGLSVTYSLQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKAPSPQWPENGTVQFNKYAVRYRPGLDLVLKGVNFSINGGEKVGIVGRTGAGKSSLTLALFRIIEAAEGEILIDGVNIADLGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWKALEHAHLKSFVKGLTAGLHHEVTEGGENLSVGQRQLICLSRALLRKTKVLILDEATAAVDLETDDLIQKTIRSEFKNCTVLTIAHRLNTIMDSDRVVVLDNGRIVEFDSPSNLLKQQQSIFYSMCKDAG 1523
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1133439956|ref|XP_019876351.1| (PREDICTED: LOW QUALITY PROTEIN: multidrug resistance-associated protein 1-like [Aethina tumida]) HSP 1 Score: 1253.04 bits (3241), Expect = 0.000e+0 Identity = 684/1522 (44.94%), Postives = 966/1522 (63.47%), Query Frame = 0
Query: 174 DPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIF--VNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDI-QSLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLALE-----DKASCLSLLLFSWMDGLLWDGFRRPLT----WTRLPQ---------FPRSMNVT--DNTATFMNQWRTQV--KDKLVDF-TTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKD------PDEPKV---MLPDVIAETPDQQESTLVVELEKT-----------------SNGTKAD---LIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWADYNQD--HPDLATASTTYYLGIYAGIGLVGMIINLI--REFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
D FC F+D N +WNTTDP++T C T+LV PCA FL + I IY + N + + P L L +T+ L + V+L+ + G K+ +I+ + +L+ + L + S FLFWL L LC + + +I Q+ + V ++V ++ Y+P+VL + + C D P ++ LE + AS LS L FSW D L W GF++PL W PQ F + N+T ++F R VDF + + S+ P L+ + G L V+ + L+ FV+P IL LLI V K+ W+G+ Y +LLA++TV TI Y + + +++R++L+ +Y+K+LK+SN RK TVGE+ NLM+VDAQ+ V+ + + ++ ++P I ++LYFL+ ELG + +GL +IP+N + + + LQ+ Q++ KD R+KL+NE+L+G+KVLKLYAWE F +++ +IR EIKV++ A + A +F +S P LV++V F YV +D +VL A K + S+SLFN++R PL M P T+ + V+ VS KRINKFLN+ E++P NV H D + I N +W ++ P+L IN+ +P+GSL+A+VGTVG GKSSL+A+ LGEME++SG+V V GSIAYV QQAWIQN TL+DNILF +++ YDKVV+ C L+ D +L D TEIGE GIN SGGQKQRVSLARAVY+D+DIYLLDDPLSAVD+HVGK IF V+ +G L KTRVLVTH I +L + D I+V+KNG+++ESG+YQ+LL +F+EFL+Q+ S+ + D D PDE K + ++E+ +++ ++ +K+ +G+K + LIE E + +G V WEVY Y++S+G L V + + + G ++ L WAD ++D + T YLG+YA +G + ++ F A++ +H LL +MR PM+FFDT P GRI++RFS D+D +D +P + +L+ F+ + +V+I +TP F VI P+ ++YY IQRF++ TSRQ+KRLES+S+SPI++HF E +TG +IRA++Q+ RF+ ES+ +V + C + ++ ++RWL R+E++GNL++FFAA+FAVL +++L PG+ GLS+TY+L I TLNW++RM E+ETN VA+ERI EY EA W++P +WP GAV F++YA RYR GLDLVLKG++ V EKIGI GRTGAGKSSLTL+LFRIIEA +G I IDG IS+LGLHTLRSR+TIIPQDPVLF+G+LR NLDP E YSD E+W +LEHAHLK + GL GL HE+ EGGEN SVGQRQLICLARALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CT++TIAHRLNTI+D DR+ V GQI EF SPA LL + S +M DAG
Sbjct: 7 DVFCGSDFWDYNLSWNTTDPDLTKCFERTVLVWFPCA-FLWTFSILEIY--YIANSKKRDI-PWNWLNLSKLVVTVALCVLSAVDLVTSIKNAKNENGSMPKV---DIYTPVIKIISFLLSAVLLVFNKKHGLQTSGLQFLFWLLLALCGAVQFRTEIRQAQVQVPEPYYDYVSYMIYYPLVLAMLLLNCLADKSPKHTQYAKLEKPCPEEGASFLSKLFFSWFDSLAWLGFKKPLEAEDLWDMNPQDSAKEVVQLFEKHWNMTLQKCESSFSQHTRASFTQNSASVDFVNSNKKKQASIVPALIASFGPTFLFGAVLNVIQDLMTFVSPMILGLLITFVKEKQEDWKGYTYAVLLLATATVQTIIMSQYFNRMFIVGMRIRTALIATIYKKALKISNATRKGTTVGEIVNLMAVDAQKFVELTIYLNTIWSAPIQISLSLYFLWYELGPSIFAGLVTMISMIPLNGYIANKMKVLQIKQMKNKDHRVKLMNEILSGIKVLKLYAWEPSFEKQVLEIRSKEIKVLKELAYMNAGTSFIWSCAPFLVSLVTFATYVLVDERNVLDANKAYVSISLFNILRYPLSMLPMTITQMVQSWVSVKRINKFLNSEELNPNNVTH--DQKEVDTIVFGNGNFSWGDE---PVLKNINIRLPKGSLSAVVGTVGCGKSSLIAAALGEMERISGRVNVVGSIAYVSQQAWIQNATLRDNILFGKKFDKKIYDKVVKACALKPDFDMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYADSDIYLLDDPLSAVDSHVGKHIFDHVI-GPKGLLGKKTRVLVTHGITYLSQTDKILVMKNGEISESGTYQELLDKKGSFAEFLLQHMSEDPTEDLDEIESLVPDEIKTEFKRMRSQVSESEGSEKANGSLKRQKSVDSSGKEIQPLISNEDLKSGSKKEGERLIEVEKSEIGSVSWEVYKYYLKSVGFFLAVATIILNVVFQGFGIGSNMWLGRWAD-DEDLVNGTQNTQRRDMYLGVYAALGFGKAVTYVLWSCSFPIMRTSIIAAKKLHAFLLSGVMRLPMTFFDTTPSGRILSRFSKDVDVLDSILPPNIFYSLYLLFEVIGTLVVISYTTPLFVIVILPIGVVYYFIQRFYVATSRQLKRLESVSRSPIYSHFGEMITGAQAIRAFEQEQRFIDESERKVDQNQVCYYPSIISDRWLAVRLEMIGNLIIFFAALFAVLGKDTL-PGLVGLSVTYALQITHTLNWLVRMSSEVETNIVAVERIKEYGEATQEAPWEVP-SKNPPSLWPEVGAVEFKNYAFRYRPGLDLVLKGVNFSVNGGEKIGIVGRTGAGKSSLTLALFRIIEAAQGEIYIDGVKISELGLHTLRSRLTIIPQDPVLFSGSLRINLDPFEKYSDDEVWRSLEHAHLKNFVKGLPSGLQHEVTEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQRTIRTEFKNCTILTIAHRLNTIMDSDRVLVLDKGQIVEFDSPATLLLNSKSIFYSMCKDAG 1512
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|642933785|ref|XP_008197283.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X1 [Tribolium castaneum] >gi|642933787|ref|XP_008197292.1| PREDICTED: multidrug resistance-associated protein 1 isoform X1 [Tribolium castaneum]) HSP 1 Score: 1251.88 bits (3238), Expect = 0.000e+0 Identity = 696/1542 (45.14%), Postives = 954/1542 (61.87%), Query Frame = 0
Query: 170 STSEDPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAH-------ISPPLFLFWLHLLLCEIPKLKIDIQ-SLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLAL-----EDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWR--------------TQVKDKL----VDF-TTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQY--------------------TSDPMSSDKDPDEPKVMLPDVIAETPDQQES-------------------TLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWA--DYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSP-MSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSR-ESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+++ D FC F++ TW+T DP++T C T+LV +PCA S + + Y ++ R P L K+ T V+FV ++ V + SE Y ++ LL G+ L + S FLFWL L +C + + +++ S + +R ++ +L Y+P+VLV+ C+ D P +++ L E+ +S LS LLFSW D L W GFRRPL + L + ++ TF W+ T+ KL VD ++ + S+ P LVK G + ++ + LL FV+P IL LLI V + E W+GF Y G L ++T+ TI Y + V +++R++L+ A+Y+K+L++SNKARK+ TVGE+ NLMSVDAQ+ +D + + + ++P I++ALYFL+ LG A L+GLAV ILIPVN + + + LQ+ Q++ KD+R+KL+NEVL+G+KVLKLYAWE F ++I IR EI+V++ A + A +F +S P LV++V F YV +D ++L A K F S+SLFN++R PL M P + V+ +VS +RINKF+NA E+DP +V H +++A IE N WDE+ +L IN+ I + SL A+VG+VG+GKSSLL++FLGEM+K SG+V G+IAYV QQAWIQN TL+DNILF + + S YDKVV C L D A+L D TEIGE GIN SGGQKQRVSLARAVY+++DIY LDDPLSAVD+HVGK IF +V+ EG L+ KTRVLVTH I +L + D IIVLK+G+V+E G+YQ+LL AFSEFL+Q+ T+ +K + + + ++ET Q S + VE K G K LIE E A G VKW VY +Y++SIG L V + + L G ++ L WA D T +YLGIY +G+ + L+ ++ +Q++H LL I+R P +FFD P+GRI+NRFS D+D +D +P L + CFF + +V+I STP F VI P+ ILYY IQRF++ TSRQ+KRLES+S+SPI++HF ET+TG+ +IRA+++QDRF+ ES+ RV C + ++ +NRWL R+E++GNL++FFAA+F+VL R ES + G+ GLS+TYSL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G V F YA RYR GLDLVLKG++ + EK+GI GRTGAGKSSLTL+LFRIIEA +G ILIDG +I+ LGLHTLRSR+TIIPQD VLF+G LR NLDP + +SD E+W ALEHAHLK + GL GL HE+ EGGEN SVGQRQLICL+RALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V +G+I EF SP+ LL S +M DAG
Sbjct: 3 ASTMDKFCGSEFWNSTLTWHTNDPDLTKCFERTVLVWVPCAFLWTFSSLEVYYILHSKRRD----IP--WNWLNVSKLLGTAVLFV------LTVTDLVTAVNSASSSESDVYKVDIYTPVIKLLSFGLSAVLLVYNRKYGLCTSGLQFLFWLSLAICGAFQYRTELRGSQEEIPESRYSYISYLIYYPVVLVMLFLNCFADRSPRRSEYPKLKNPCPEENSSFLSRLLFSWFDPLAWRGFRRPLVDSDLWDMKPEDSASEVVPTFEKHWKRILQKCESNSPTRQTRASYKLDSARVDIVNSSTKKQASILPALVKAFGPTFIFGALLKLIQDLLTFVSPHILNLLIQFVKNNEEQWKGFLYAGALFVTATIQTIVLSQYFNRMFVVGMRIRTALVSAIYKKALRVSNKARKESTVGEIVNLMSVDAQKFIDLTAYINMIWSAPLQIILALYFLWNILGPAVLAGLAVMIILIPVNGYIANKVKVLQIKQMKNKDERVKLMNEVLSGIKVLKLYAWEPSFEKQILKIRTKEIQVLKEAAYMNAGTSFIWSCAPFLVSLVSFGTYVMVDEHNILDASKAFVSVSLFNILRFPLSMLPMMISNLVQAMVSIQRINKFMNAEELDPTSVTHDSNESAPLVIE--NGCFNWDEEQ---VLKNINIRIEKKSLCAVVGSVGSGKSSLLSAFLGEMDKTSGRVNTVGTIAYVSQQAWIQNATLRDNILFGKSFDKSLYDKVVEACALNPDFAMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYANSDIYFLDDPLSAVDSHVGKHIFDKVI-GPEGLLRHKTRVLVTHGITYLPQTDKIIVLKDGEVSEGGTYQELLDKKGAFSEFLLQHINEVEEDEEELDVLKSQLSGTAVSEEINKKLSRHRSRVSESVSETGSDQTSLSLQRQKSVESADKSLRHRSSSVEEAKKVKGEK--LIEVEKAETGSVKWIVYKHYLKSIGVFLTVATILLNMLFQGFSIGSNVWLGVWADDDTVVVDNVTDTGKRDFYLGIYGALGIGQAVATLLSALSLYIGAVNGAQLLHHLLLSNILRVPCTTFFDVTPVGRILNRFSKDVDTLDNILPMTLRGWITCFFSVLGTLVVISVSTPIFIAVIVPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETITGVQAIRAFREQDRFIKESEHRVDVNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFSVLGRDESQNAGLVGLSVTYSLQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKAPSPQWPENGTVQFNKYAVRYRPGLDLVLKGVNFSINGGEKVGIVGRTGAGKSSLTLALFRIIEAAEGEILIDGVNIADLGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWKALEHAHLKSFVKGLTAGLHHEVTEGGENLSVGQRQLICLSRALLRKTKVLILDEATAAVDLETDDLIQKTIRSEFKNCTVLTIAHRLNTIMDSDRVVVLDNGRIVEFDSPSNLLKQQQSIFYSMCKDAG 1523
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1004396439|gb|KYB25508.1| (putative multidrug resistance-associated protein lethal(2)03659-like Protein [Tribolium castaneum]) HSP 1 Score: 1251.11 bits (3236), Expect = 0.000e+0 Identity = 696/1538 (45.25%), Postives = 951/1538 (61.83%), Query Frame = 0
Query: 174 DPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAH-------ISPPLFLFWLHLLLCEIPKLKIDIQ-SLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLAL-----EDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWR--------------TQVKDKL----VDF-TTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQY--------------------TSDPMSSDKDPDEPKVMLPDVIAETPDQQES-------------------TLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWA--DYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSP-MSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSR-ESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
D FC F++ TW+T DP++T C T+LV +PCA S + + Y ++ R P L K+ T V+FV ++ V + SE Y ++ LL G+ L + S FLFWL L +C + + +++ S + +R ++ +L Y+P+VLV+ C+ D P +++ L E+ +S LS LLFSW D L W GFRRPL + L + ++ TF W+ T+ KL VD ++ + S+ P LVK G + ++ + LL FV+P IL LLI V + E W+GF Y G L ++T+ TI Y + V +++R++L+ A+Y+K+L++SNKARK+ TVGE+ NLMSVDAQ+ +D + + + ++P I++ALYFL+ LG A L+GLAV ILIPVN + + + LQ+ Q++ KD+R+KL+NEVL+G+KVLKLYAWE F ++I IR EI+V++ A + A +F +S P LV++V F YV +D ++L A K F S+SLFN++R PL M P + V+ +VS +RINKF+NA E+DP +V H +++A IE N WDE+ +L IN+ I + SL A+VG+VG+GKSSLL++FLGEM+K SG+V G+IAYV QQAWIQN TL+DNILF + + S YDKVV C L D A+L D TEIGE GIN SGGQKQRVSLARAVY+++DIY LDDPLSAVD+HVGK IF +V+ EG L+ KTRVLVTH I +L + D IIVLK+G+V+E G+YQ+LL AFSEFL+Q+ T+ +K + + + ++ET Q S + VE K G K LIE E A G VKW VY +Y++SIG L V + + L G ++ L WA D T +YLGIY +G+ + L+ ++ +Q++H LL I+R P +FFD P+GRI+NRFS D+D +D +P L + CFF + +V+I STP F VI P+ ILYY IQRF++ TSRQ+KRLES+S+SPI++HF ET+TG+ +IRA+++QDRF+ ES+ RV C + ++ +NRWL R+E++GNL++FFAA+F+VL R ES + G+ GLS+TYSL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G V F YA RYR GLDLVLKG++ + EK+GI GRTGAGKSSLTL+LFRIIEA +G ILIDG +I+ LGLHTLRSR+TIIPQD VLF+G LR NLDP + +SD E+W ALEHAHLK + GL GL HE+ EGGEN SVGQRQLICL+RALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V +G+I EF SP+ LL S +M DAG
Sbjct: 2 DKFCGSEFWNSTLTWHTNDPDLTKCFERTVLVWVPCAFLWTFSSLEVYYILHSKRRD----IP--WNWLNVSKLLGTAVLFV------LTVTDLVTAVNSASSSESDVYKVDIYTPVIKLLSFGLSAVLLVYNRKYGLCTSGLQFLFWLSLAICGAFQYRTELRGSQEEIPESRYSYISYLIYYPVVLVMLFLNCFADRSPRRSEYPKLKNPCPEENSSFLSRLLFSWFDPLAWRGFRRPLVDSDLWDMKPEDSASEVVPTFEKHWKRILQKCESNSPTRQTRASYKLDSARVDIVNSSTKKQASILPALVKAFGPTFIFGALLKLIQDLLTFVSPHILNLLIQFVKNNEEQWKGFLYAGALFVTATIQTIVLSQYFNRMFVVGMRIRTALVSAIYKKALRVSNKARKESTVGEIVNLMSVDAQKFIDLTAYINMIWSAPLQIILALYFLWNILGPAVLAGLAVMIILIPVNGYIANKVKVLQIKQMKNKDERVKLMNEVLSGIKVLKLYAWEPSFEKQILKIRTKEIQVLKEAAYMNAGTSFIWSCAPFLVSLVSFGTYVMVDEHNILDASKAFVSVSLFNILRFPLSMLPMMISNLVQAMVSIQRINKFMNAEELDPTSVTHDSNESAPLVIE--NGCFNWDEEQ---VLKNINIRIEKKSLCAVVGSVGSGKSSLLSAFLGEMDKTSGRVNTVGTIAYVSQQAWIQNATLRDNILFGKSFDKSLYDKVVEACALNPDFAMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYANSDIYFLDDPLSAVDSHVGKHIFDKVI-GPEGLLRHKTRVLVTHGITYLPQTDKIIVLKDGEVSEGGTYQELLDKKGAFSEFLLQHINEVEEDEEELDVLKSQLSGTAVSEEINKKLSRHRSRVSESVSETGSDQTSLSLQRQKSVESADKSLRHRSSSVEEAKKVKGEK--LIEVEKAETGSVKWIVYKHYLKSIGVFLTVATILLNMLFQGFSIGSNVWLGVWADDDTVVVDNVTDTGKRDFYLGIYGALGIGQAVATLLSALSLYIGAVNGAQLLHHLLLSNILRVPCTTFFDVTPVGRILNRFSKDVDTLDNILPMTLRGWITCFFSVLGTLVVISVSTPIFIAVIVPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETITGVQAIRAFREQDRFIKESEHRVDVNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFSVLGRDESQNAGLVGLSVTYSLQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKAPSPQWPENGTVQFNKYAVRYRPGLDLVLKGVNFSINGGEKVGIVGRTGAGKSSLTLALFRIIEAAEGEILIDGVNIADLGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWKALEHAHLKSFVKGLTAGLHHEVTEGGENLSVGQRQLICLSRALLRKTKVLILDEATAAVDLETDDLIQKTIRSEFKNCTVLTIAHRLNTIMDSDRVVVLDNGRIVEFDSPSNLLKQQQSIFYSMCKDAG 1518
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|328706529|ref|XP_003243122.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X1 [Acyrthosiphon pisum]) HSP 1 Score: 1240.33 bits (3208), Expect = 0.000e+0 Identity = 676/1522 (44.42%), Postives = 952/1522 (62.55%), Query Frame = 0
Query: 174 DPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRR-P-HTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQ-SLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLALED-----KASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNT----ATFMNQW-RTQVKDKLVDFT--------------------------TTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHV-NSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLI-------QYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVVELEKTSNGTK----------ADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWA--DYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
D FC PF+D N +WNTTDP+VT C T LV PC + P+ + Y ++ R P + + K G L L+ ++L + S + +S + + G ++L + + S +FLFWL L C + + + +I+ + V + +++ ++ Y+P+VL+ FI + D P + + +E KAS S +LF+W D L W G+ RPL L +MN D++ F W R+ +K KL+D T + S+ P L K+ G + + I L FV+PQ+LK LI V NS EP W+G+FY +++ ++T+ T+ Y + + +++R++L A+YRK+L++SN ARK +TVGE+ NLM+VDA R VD + + + ++P I +A+YFL+ LG + L+GL V +LIP+N + A LQ+ Q++ KD+R+KL+NE+L+G+KVLKLYAWE F +++ DIR EIKV++ A L A +F ++ P LV++V F VYV D SHVL A+ F SLSLFN++R PL M P + V+ VS KRINKF+N+ E+DP +V H D+ K+ + + N T TW E T P L INL + G L A+VGTVG+GKSSL+++FLGEMEK+SG+ +GSIAYVPQQAWIQN +LKDNILF Q S Y+KV+ C L +D +L D TEIGE GIN SGGQKQRVSLARAVY ++DIY LDDPLSAVD+HVGK IF V+ T G L+ KTR+LVTH+I +L ++D I+V+K+G+V+ESG+Y++LL F++FLI +Y D + DK ++ L + + S ++ +++ + K A LIE E A G VKWEVY++Y++SIG L + V + + G ++ LS W+ D + H + YL +Y +G ++ + + A++ ++E + +I ++P+S FDT PIGRI+NR S DID ID +PF L T+ F V +V+I STP F VI P+ ILYY IQRF++ TSRQ+KRLES+S+SPI++HFSETVTG +SIRAY + +F+ +S+ +V C + + ANRWL R+E +GN ++FF+++F+VL R++LSPG+ GLS++Y+L I TLNW++RM E+ETN VA+ERI EY EA WD+P + WP G V F++ RYR+GLDL LKG+D+ V +K+GI GRTGAGKSSLTLSLFRI+EA +G IL+DG DIS +GLHTLRSR+TIIPQDPVLF+G LR NLDP +D ++W+AL+ AHLK H+ GL GGLD+E++EGG+N SVGQRQL+CLARALLRKTK+LVLDEATAA+DL TDDLIQTTIR EF+ CTV+TIAHRLNTI+D D++ V +G + E+ SPA LL + SS M DAG
Sbjct: 7 DGFCGSPFWDWNTSWNTTDPDVTLCFEKTALVWSPCLFLWLFCPLEVYYLVHSRYRDIPWNWLNLAKLGG----AAILCLLSIIDLAYAIIQYSSGMPIYSVDFYTPLVKLITFGFIMVL----ISANRARGLRSSGLIFLFWLSLAFCGMIQYRTEIRLAFSDVPLQKYQFISYMVYYPLVLIQFILNFFADADPRLSDYPPVEKPCPEMKASYPSRILFTWFDTLAWTGYNRPLETKDL----WNMNYDDSSREVVPIFDKHWERSLIKAKLLDDAKASYIKHKSDGSIEVSPTEYTRITRGTKSQNEASILPALCKSFGRTFMFGTFLKIIEDCLVFVSPQVLKYLIAFVGNSNEPLWRGYFYVFLMMLTATLQTLILSQYFHRMYLVGMRVRTALTSAIYRKALRISNTARKTFTVGEIVNLMAVDAHRFVDLTTYLNMIWSAPFQIALAIYFLWQSLGPSVLAGLFVMIVLIPINGVVAAKARNLQIKQMKNKDQRVKLMNEILSGIKVLKLYAWEPSFEQKVLDIRGKEIKVLRTAAYLNAATSFIWACAPFLVSLVTFAVYVLSDDSHVLDAQTAFVSLSLFNILRFPLSMLPMFVSNVVQSSVSVKRINKFMNSEELDPDSVTHDSDE--KDPLVIENGTFTWGEPTDAPTLSNINLRVSSGQLVAVVGTVGSGKSSLVSAFLGEMEKVSGRANTKGSIAYVPQQAWIQNTSLKDNILFGQTLSDRAYNKVIDACALRADFQMLPAGDDTEIGEKGINLSGGQKQRVSLARAVYKESDIYFLDDPLSAVDSHVGKHIFEHVIGPT-GLLRKKTRILVTHSITYLREVDLIVVMKDGQVSESGTYKELLDKKGDFADFLILHMQEQNEYKVDEIEIDKLLEDAPADLKEKYVRQRSESNSNSSMQRQRSIDSEKNIPLPIIEQQAKLIEVEKAETGSVKWEVYVHYLKSIGPFLCISTVVLSIIFQGFSISSNIWLSVWSNDDTSHVHGTENISKRNLYLTVYGLLGFGQVVSTVTAAIALSLGTVVAAEKLYELINARIFKNPLSLFDTTPIGRILNRVSKDIDTIDNVLPFILRSTIQTVFSVVGTLVVISYSTPVFTAVIIPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFSETVTGASSIRAYGAESKFIIQSEQKVDFNQTCYYPSTVANRWLAVRLETIGNFIIFFSSVFSVLGRDTLSPGIVGLSVSYALQITQTLNWLVRMTSEVETNIVAVERIKEYGETPQEAPWDVPSNLPAKD-WPTSGEVQFKNLKVRYREGLDLALKGLDILVEGGQKVGIVGRTGAGKSSLTLSLFRIVEAAEGSILVDGVDISNIGLHTLRSRLTIIPQDPVLFSGTLRMNLDPTNSNTDEQLWNALKLAHLKAHVKGLIGGLDYEVSEGGDNLSVGQRQLVCLARALLRKTKLLVLDEATAAIDLETDDLIQTTIRSEFKDCTVLTIAHRLNTIMDSDKVIVLDNGFMVEYDSPANLLQEKSSVFYLMAKDAG 1512
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1008451091|ref|XP_015838719.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X5 [Tribolium castaneum]) HSP 1 Score: 1239.17 bits (3205), Expect = 0.000e+0 Identity = 695/1542 (45.07%), Postives = 954/1542 (61.87%), Query Frame = 0
Query: 170 STSEDPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQNWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAH-------ISPPLFLFWLHLLLCEIPKLKIDIQ-SLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLAL-----EDKASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNTATFMNQWR--------------TQVKDKL----VDF-TTTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHVNSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQY--------------------TSDPMSSDKDPDEPKVMLPDVIAETPDQQES-------------------TLVVELEKTSNGTKADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWA--DYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHF-VNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSR-ESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLPLDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
+++ D FC F++ TW+T DP++T C T+LV +PCA S + + Y ++ R P L K+ T V+FV ++ V + SE Y ++ LL G+ L + S FLFWL L +C + + +++ S + +R ++ +L Y+P+VLV+ C+ D P +++ L E+ +S LS LLFSW D L W GFRRPL + L + ++ TF W+ T+ KL VD ++ + S+ P LVK G + ++ + LL FV+P IL LLI V + E W+GF Y G L ++T+ TI Y + V +++R++L+ A+Y+K+L++SNKARK+ TVGE+ NLMSVDAQ+ +D + + + ++P I++ALYFL+ LG A L+GLAV ILIPVN + + + LQ+ Q++ KD+R+KL+NEVL+G+KVLKLYAWE F ++I IR EI+V++ A + A +F +S P LV++V F YV +D ++L A K F S+SLFN++R PL M P + V+ +VS +RINKF+NA E+DP +V H +++A IE N WDE+ +L IN+ I + SL A+VG+VG+GKSSLL++FLGEM+K SG+V G+IAYV QQAWIQN TL+DNILF + + S YDKVV C L D A+L D TEIGE GIN SGGQKQRVSLARAVY+++DIY LDDPLSAVD+HVGK IF +V+ EG L+ KTRVLVTH I +L + D IIVLK+G+V+E G+YQ+LL AFSEFL+Q+ T+ +K + + + ++ET Q S + VE K G K LIE E A G VKW VY +Y++SIG L V + + L G ++ L WA D T +YLGIY +G +G I + L+ + A+ IH+ LL I R PMSFF+ P+GRI++RFS D+ +D+++PF + + + +V+I STP F VI P+ ILYY IQRF++ TSRQ+KRLES+S+SPI++HF ET+TG+ +IRA+++QDRF+ ES+ RV C + ++ +NRWL R+E++GNL++FFAA+F+VL R ES + G+ GLS+TYSL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G V F YA RYR GLDLVLKG++ + EK+GI GRTGAGKSSLTL+LFRIIEA +G ILIDG +I+ LGLHTLRSR+TIIPQD VLF+G LR NLDP + +SD E+W ALEHAHLK + GL GL HE+ EGGEN SVGQRQLICL+RALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V +G+I EF SP+ LL S +M DAG
Sbjct: 3 ASTMDKFCGSEFWNSTLTWHTNDPDLTKCFERTVLVWVPCAFLWTFSSLEVYYILHSKRRD----IP--WNWLNVSKLLGTAVLFV------LTVTDLVTAVNSASSSESDVYKVDIYTPVIKLLSFGLSAVLLVYNRKYGLCTSGLQFLFWLSLAICGAFQYRTELRGSQEEIPESRYSYISYLIYYPVVLVMLFLNCFADRSPRRSEYPKLKNPCPEENSSFLSRLLFSWFDPLAWRGFRRPLVDSDLWDMKPEDSASEVVPTFEKHWKRILQKCESNSPTRQTRASYKLDSARVDIVNSSTKKQASILPALVKAFGPTFIFGALLKLIQDLLTFVSPHILNLLIQFVKNNEEQWKGFLYAGALFVTATIQTIVLSQYFNRMFVVGMRIRTALVSAIYKKALRVSNKARKESTVGEIVNLMSVDAQKFIDLTAYINMIWSAPLQIILALYFLWNILGPAVLAGLAVMIILIPVNGYIANKVKVLQIKQMKNKDERVKLMNEVLSGIKVLKLYAWEPSFEKQILKIRTKEIQVLKEAAYMNAGTSFIWSCAPFLVSLVSFGTYVMVDEHNILDASKAFVSVSLFNILRFPLSMLPMMISNLVQAMVSIQRINKFMNAEELDPTSVTHDSNESAPLVIE--NGCFNWDEEQ---VLKNINIRIEKKSLCAVVGSVGSGKSSLLSAFLGEMDKTSGRVNTVGTIAYVSQQAWIQNATLRDNILFGKSFDKSLYDKVVEACALNPDFAMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYANSDIYFLDDPLSAVDSHVGKHIFDKVI-GPEGLLRHKTRVLVTHGITYLPQTDKIIVLKDGEVSEGGTYQELLDKKGAFSEFLLQHINEVEEDEEELDVLKSQLSGTAVSEEINKKLSRHRSRVSESVSETGSDQTSLSLQRQKSVESADKSLRHRSSSVEEAKKVKGEK--LIEVEKAETGSVKWIVYKHYLKSIGVFLTVATILLNMLFQGFSIGSNVWLGVWADDDTVVVDNVTDTGKRDFYLGIYGALG-IGQAITICSSELNLTIASLNAASEIHKGLLLNIFRQPMSFFELVPVGRILSRFSKDLSGVDEELPFNCYEVIESTCIVLGTLVVISVSTPIFIAVIVPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETITGVQAIRAFREQDRFIKESEHRVDVNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFSVLGRDESQNAGLVGLSVTYSLQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKAPSPQWPENGTVQFNKYAVRYRPGLDLVLKGVNFSINGGEKVGIVGRTGAGKSSLTLALFRIIEAAEGEILIDGVNIADLGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWKALEHAHLKSFVKGLTAGLHHEVTEGGENLSVGQRQLICLSRALLRKTKVLILDEATAAVDLETDDLIQKTIRSEFKNCTVLTIAHRLNTIMDSDRVVVLDNGRIVEFDSPSNLLKQQQSIFYSMCKDAG 1522
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|985769396|gb|AMD40296.1| (multidrug resistance-associated protein 1 [Rhopalosiphum padi]) HSP 1 Score: 1239.17 bits (3205), Expect = 0.000e+0 Identity = 680/1535 (44.30%), Postives = 950/1535 (61.89%), Query Frame = 0
Query: 174 DPFCRDPFFDLNRTWNTTDPNVTPCIRDTLLVGIPCAAFLISSPIWIIYQ----------NWAQNRRPHTVTPKKCGALFYLKITLTLVIFVNLLGQLWCTSEHVGGWSKLVPSEIFHYSCLGVFVILALLQLGVDNYLKAHISPPLFLFWLHLLLCEIPKLKIDIQ-SLMAVSGTREEWVLFLTYFPIVLVLFITQCWVDIRPSSAKHLALED-----KASCLSLLLFSWMDGLLWDGFRRPLTWTRLPQFPRSMNVTDNT----ATFMNQW-RTQVKDKLVDFT--------------------------TTIRPFVSLWPILVKNHGWRLLISVVIAIFHHLLPFVNPQILKLLINHV-NSKEPTWQGFFYTGILLASSTVSTITFHVYQQLLSVSAIQMRSSLLGAVYRKSLKLSNKARKQYTVGEMTNLMSVDAQRIVDHSPNMMSLITSPCTIVIALYFLYMELGLAGLSGLAVFAILIPVNVFGSKWAEELQVTQLEAKDKRLKLLNEVLNGMKVLKLYAWETPFMRRISDIRFTEIKVIQLCARLWALMNFTFSSTPILVTIVVFCVYVAIDPSHVLTAEKIFFSLSLFNLMRIPLVMFPFTLVECVKVVVSFKRINKFLNANEIDPKNVNHTLDDAAKNAIELTNATLTWDEDTGKPLLDKINLSIPRGSLTAIVGTVGAGKSSLLASFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLKDNILFDQEYSSSQYDKVVRDCQLESDLAILKHQDHTEIGENGINFSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNINFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSDPMSSDKDPDEPKVMLPDVIAETPDQQESTLVVELEKTSNGT--------------------KADLIEEETALVGKVKWEVYMNYVQSIGSLLFVFIVTMYALGAGTEAIAHYSLSHWA--DYNQDHPDLATASTTYYLGIYAGIGLVGMIINLIREFLHFVNCAKASQVIHEKLLKQIMRSPMSFFDTNPIGRIINRFSSDIDAIDQKIPFGLSDTLWCFFDTVTIIVIICSSTPTFAYVIPPLTILYYIIQRFFITTSRQIKRLESMSKSPIFAHFSETVTGLASIRAYQQQDRFLHESQARVQKCANCTFLNVSANRWLGTRVEVLGNLVVFFAAIFAVLSRESLSPGMAGLSITYSLNIMDTLNWMIRMLCELETNSVALERILEYTHNVPEAEWDLP--LDPKVGHVWPAEGAVSFESYATRYRDGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDISQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIYSDGEIWSALEHAHLKGHIGGLKGGLDHEINEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQTTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLADPSSALKAMVNDAG 1636
D FC PF+D N +WNTTDP+VT C T LV PC + SP+ + Y NW K GA +++ + + + V ++ LV F ++ + +I A GV + S +FLFWL L C + + + + + + V + + + ++ Y+P+VL+ F+ + D P + + +E KAS S +LF+W D L W G+ RPL L +MN D++ F W R+ +K KL+D T S+ P L K+ G L + + L FV+PQ+LK LI V N+ EP W+G+FY +++ ++T+ T+ Y + + +++R++L A+YRK+L++SN ARK +TVGE+ NLM+VDA R VD + + + ++P I +A+YFL+ LG + L+GL V +LIP+N F + A LQ+ Q++ KD+R+KL+NE+L+G+KVLKLYAWE F +++ DIR EIKV++ A L A +F ++ P LV++V F VYV D SHVL A+ F SLSLFN++R PL M P + V+ VS KRINKF+N+ E+DP +V H D+ K+ + + N T TW E T P L INL + G L A+VGTVG+GKSSL+++FLGEMEK+SG+V +GSIAYVPQQAWIQN +LKDNILF Q S Y+KV+ C L +D +L D TEIGE GIN SGGQKQRVSLARAVY ++DIY LDDPLSAVD+HVGK IF V+ T G L+ KTR+LVTH+I +L +D I+V+K+G+V+ESG+Y++LL F++FLI + + D E +L D A D +E + E SN + +A LIE E A G VKWEVY++Y++SIG L + V + + G ++ LS W+ D + H + YL +Y +G + + + + KAS ++H + + R+PM FFD P GRI++RFS D++ +D K+ LSDT++CF D + +V+I STP F VI P+ I+YY IQRF++ TSRQ+KRLES+S+SPI++HFSETVTG SIRAY + +F+ +S+ +V C + + ANRWL R+E +GN ++FF+++F+VL R++LSPG+ GLS++Y+L I TLNW++RM E+ETN VA+ERI EY EA WD+P L PK WP G V F++ RYR+GLDL LKG+D+ V +K+GI GRTGAGKSSLTLSLFRI+EA +G IL+DG DIS +GLHTLR R+TIIPQDPVLF+G LR NLDP +D ++W++L+ AHLK ++ GL GGLD+E++EGG+N SVGQRQL+CLARALLRKTK+LVLDEATAA+DL TDDLIQTTIR EF+ CTV+TIAHRLNTI+D D++ V +G + E+ SPA LL + SS M DAG
Sbjct: 7 DSFCGSPFWDWNLSWNTTDPDVTLCFEKTALVWSPCLFLWLFSPLEVYYLVHSRYRDIPWNWLN-------LTKMGGAAILCLLSIIDIAYAIIQYSSGMPIYSVDFYTPLVKLITFGFTMV---LISANRARGVRS------SGLIFLFWLSLAFCGVVQYRTEFRLAFSDVPSQKYQLISYMVYYPLVLIQFVLNFFADTDPRLSDYPPVEKPCPEMKASYPSRILFTWFDALAWTGYNRPLETKDL----WNMNYDDSSREVVPIFDKHWERSLIKAKLLDNAKASYIKHKSDGSIEVSPTEYSRITRGTKSENEASILPALCKSFGRTFLFGTFLKVIEDCLVFVSPQVLKYLIAFVGNTNEPLWRGYFYVFLMMLTATLQTLILSQYFHRMYLVGMRVRTALTSAIYRKALRISNTARKTFTVGEIVNLMAVDAHRFVDLTTYLNMIWSAPFQIGLAIYFLWQSLGPSVLAGLFVMIVLIPINGFVAAKARNLQIKQMKNKDQRVKLMNEILSGIKVLKLYAWEPSFEQKVLDIRGKEIKVLRTAAYLNAATSFIWACAPFLVSLVTFAVYVLSDDSHVLDAQTAFVSLSLFNILRFPLSMLPMFVSNVVQSSVSVKRINKFMNSEELDPDSVTHDSDE--KDPLVIENGTFTWGELTDPPTLSNINLRVSSGQLVAVVGTVGSGKSSLVSAFLGEMEKVSGRVNTKGSIAYVPQQAWIQNTSLKDNILFGQTLSDRAYNKVIDACALRADFQMLPAGDETEIGEKGINLSGGQKQRVSLARAVYKESDIYFLDDPLSAVDSHVGKHIFEHVIGPT-GLLRKKTRILVTHSITYLRDVDLIVVMKDGQVSESGTYKELLDKKGDFADFLILHMQEQNELKVDEIEIDKLLEDAPA---DLKEKYVRQRSESNSNSSMQRQRSIDSEKTIPLPIIDQQAKLIEVEKAETGSVKWEVYVHYLKSIGPFLCISTVVLSIIFQGFSISSNIWLSIWSNDDSSHVHGKENISKRNLYLSVYGLLGFGQGLFEFLADLCLCLGAWKASVMLHNYMAGNVFRNPMKFFDATPTGRILSRFSGDVEVVD-KLSQQLSDTVYCFMDVIGTLVVISYSTPVFTAVIIPIGIIYYFIQRFYVATSRQLKRLESVSRSPIYSHFSETVTGATSIRAYGAESKFILQSEQKVDFNQTCYYPSTVANRWLAVRLETIGNFIIFFSSVFSVLGRDTLSPGIVGLSVSYALQITQTLNWLVRMTSEVETNIVAVERIKEYGETPQEAPWDIPSNLPPKE---WPTNGEVQFKNLKVRYREGLDLALKGLDILVEGGQKVGIVGRTGAGKSSLTLSLFRIVEAAEGSILVDGVDISNIGLHTLRGRLTIIPQDPVLFSGTLRMNLDPTNSNTDEQLWNSLKLAHLKEYVKGLVGGLDYEVSEGGDNLSVGQRQLVCLARALLRKTKLLVLDEATAAIDLETDDLIQTTIRSEFKDCTVLTIAHRLNTIMDSDKVIVLDNGFMVEYDSPANLLQEKSSVFYLMAKDAG 1511 The following BLAST results are available for this feature:
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 19
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BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold3214_size9680:262..7304+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>snap_masked-scaffold3214_size9680-processed-gene-0.0 ID=snap_masked-scaffold3214_size9680-processed-gene-0.0|Name=multidrug resistance-associated protein 1 isoform x3|organism=Tigriopus kingsejongensis|type=gene|length=7043bp|location=Sequence derived from alignment at scaffold3214_size9680:262..7304+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'multidrug resistance-associated protein 1 isoform x3' has the following synonyms
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