intersectin-1 isoform x2, maker-scaffold96_size378025-snap-gene-2.51 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000007494 (supercontig:LSalAtl2s:LSalAtl2s430:159418:165885:1 gene:EMLSAG00000007494 transcript:EMLSAT00000007494 description:"maker-LSalAtl2s430-augustus-gene-1.21") HSP 1 Score: 444.121 bits (1141), Expect = 1.169e-140 Identity = 284/643 (44.17%), Postives = 393/643 (61.12%), Query Frame = 0
Query: 44 WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGS--SRAESVVSPSTFEDKRRENFNKGQAELEKRRQSIVDQQKREADERKKKEAAEAVEKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTDPDHAWGNEEPEPVS--------------AGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVE------TDIVAKVIVDWTG--EDSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELV------------LPTDSLPTEV-FVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYV 649
W I TR KY+ +F Q D++R GFL G+ ARN LL++GLPQN LAQIW LSD D +G+LS +EFI+SGYLCDLA KGEP+P LPS+++PPS R ++ G V TP S S AE + SP++FEDKRRENFNKG AELE+RRQS++DQQ++E DERKKKE EA E+EKQ++ELERQR+ EWE RK EL HRQ EQEK+L LKAKQ N+K +++ +R+++K++T I++ R+GV DVK+FID MRSSRD KM MNALK + + K+T K ++ E+++ FE ++ EK+K+V ++ L +K K E K + + ++ L +E L IIE C+ L+ FDE+RRE++AEK+KR+RELTDPD AWG P + + + + ++ ALY++E N+DEL FK G+ I+VH D EPGWLGGE NG+ GWFPE + AL+ IA EE + +V+ DWT S+ K I V + W G+ + + G+FP+ ++ E+ T V TD+ +E+ VA PY S E GDL F++G I ++ + +WWTG+ D+ GVFP NYV
Sbjct: 234 WGIPPPTRVKYATVFNQSDRARTGFLAGVPARNILLRSGLPQNTLAQIWALSDADNDGRLSLEEFILSGYLCDLAQKGEPMPNVLPSNLLPPSQRKNKEVIISGTASNGGGVGTPSSVKSAAEELSSPTSFEDKRRENFNKGHAELERRRQSLIDQQRKEEDERKKKEKEEAEEREKQKRELERQRLAEWEAQRKAELIQHRQREQEKVLFLKAKQDNLKQELEANREKVKNLTTNISDTRSGVTDVKTFIDGMRSSRDSKMGDMNALKLEARS------KITDAK----------IAEGRDEELSHFEVKKQEKEKEVNVLREKLAILKNKEEEKKDKYNSVKKILLELEEKLKLIIEVCRKLFSQFDEQRREVRAEKAKRIRELTDPDAAWGVGFEVPTTETVVINTNIVHHLQSPVKNQEYIKYRALYEYEARNDDELGFKVGEFILVHPGQDHEPGWLGGELNGRVGWFPEAYAERVDGALQPIAEEETAGSNSTLSXSTVRVLYDWTAIKRSELSIEKDQTINVTSISNDNWWQGESSEGKK-GYFPANFVTTEHLEKRGTTPTEVPEVIGSSPSIDEPQTDAPTSEIRCVALYPYNSEELGDLTFDQGDIIYLVSQAEDWWTGRIGDRTGVFPFNYV 859 HSP 2 Score: 153.295 bits (386), Expect = 2.630e-38 Identity = 137/449 (30.51%), Postives = 206/449 (45.88%), Query Frame = 0
Query: 443 SAGGDSSDAVEAY-ALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYD--------PSALEAI-----AAEEVETD-----IVAKVIVDWTGEDSFSMV-KGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVN-TDELVLPTDS---LPT------EVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVGPAKDLG------------------------NVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVKEV 837
+AG +S+ + LYD+ EL+ + D+ I ++ + W G GK G+FP FVT + P+ + + + +E +TD I + + E+ + +II + E+W G++ D G FP + + D N T +V T+ LP EV V +P + + + EE +K V + ++ TG +++ VVP AG +A A VE + + ++ DES K+ E+A VVAPYEATS EQ+SL +GQMI+I+KK +GWWQGEVQGGKGKKRQ+GWFPA+YVK++ K ALF Y DEL+F+ DII L+SKE+ WW+G+ + + G+FP NYV+ V
Sbjct: 710 TAGSNSTLSXSTVRVLYDWTAIKRSELSIEK-DQTINVTSISNDNWWQGESSEGKKGYFPANFVTTEHLEKRGTTPTEVPEVIGSSPSIDEPQTDAPTSEIRCVALYPYNSEELGDLTFDQGDIIYLVSQAEDWWTGRIGDR--TGVFPFNYVEIIQDSTLKNDTSTIVNNTNDVQELPVKETESQEVNVDELPESIAKKTEEISEENKKENVTLDDT---TGGVTNEIKA----EVVPPSNAGTSSASA-----VVVEGTGTTKRKNKKKK-----DESG-------------KSPEIATVVAPYEATSKEQISLQKGQMILIKKKNSTGWWQGEVQGGKGKKRQLGWFPANYVKIVGGLSSSSSDKQFSAANTPASQDDSTPKVESSVTTEKQTFRALFPYIANHEDELAFEADDIITLISKEEEAWWKGECKGQIGVFPSNYVEIV 1125 HSP 3 Score: 60.077 bits (144), Expect = 2.093e-9 Identity = 48/180 (26.67%), Postives = 85/180 (47.22%), Query Frame = 0
Query: 599 EVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSE-WWTGQYDD------KLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLE 771
E+ PY++T + ++GQ I + KNS WW G+ +LG FP+NYV G + +++ + AAN P + D + P+++ V + +T + + PY A ++L+ +I + K + WW+GE +G QIG FP++YV+++E
Sbjct: 974 EIATVVAPYEATSKEQISLQKGQMILIKKKNSTGWWQGEVQGGKGKKRQLGWFPANYVKIVGGLSSSSSD---------------KQFSAANTPASQDDST--PKVE-SSVTTEKQTF---RALFPYIANHEDELAFEADDIITLISKEEEAWWKGECKG------QIGVFPSNYVEIVE 1126 HSP 4 Score: 58.9214 bits (141), Expect = 5.759e-9 Identity = 27/78 (34.62%), Postives = 46/78 (58.97%), Query Frame = 0
Query: 44 WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKG 121
W+I+ R ++ + F + G++ GIQA+ +Q+GLP LA+IW L+D+D +G++S EF ++ L KG
Sbjct: 3 WSISPIERQRHGDQFSSIGPVD-GYVNGIQAKGFFMQSGLPPKTLAEIWALADMDSDGRMSFQEFSIACKLITNTLKG 79
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000010523 (supercontig:LSalAtl2s:LSalAtl2s69:194548:200631:-1 gene:EMLSAG00000010523 transcript:EMLSAT00000010523 description:"augustus_masked-LSalAtl2s69-processed-gene-2.6") HSP 1 Score: 98.5969 bits (244), Expect = 2.523e-21 Identity = 69/226 (30.53%), Postives = 111/226 (49.12%), Query Frame = 0
Query: 44 WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVSPSTFEDKRRENFNKGQAELEKRRQSIVDQQ------KREADERKKKEA-----AEAVEKEKQRQELER---QRIMEWEDNRKKELNSHRQNEQEKLLQLKA 255
W I G R +Y +F Q D R G++ G++ +N LQTGLPQN+LA IW LSD+ GKL+ ++F ++ +L G+ P L D+IPPS R +T S SS + + ++ E NK + + E++ ++ Q+ K+E D+ K +E + EKE +R +L+ Q ++E +N+ K L+ + E L Q A
Sbjct: 266 WVINSGDRLRYQALFKQTDTDRDGYVSGVEIKNVFLQTGLPQNILAHIWNLSDMKQEGKLNPEQFALAMWLIQRKQAGKDPPAALTPDMIPPSMR--------------TTASEQKSSLDGDLQGLFSRIEEENEKINKLRTQAEEQETKLLSQEEEVLGKKKELDDLKAEEKQLLEDIKKCEKEIERYDLDEKVAQDLLEETENKLKNLSEAETHMNEALKQFAA 477 HSP 2 Score: 57.3806 bits (137), Expect = 1.248e-8 Identity = 34/101 (33.66%), Postives = 54/101 (53.47%), Query Frame = 0
Query: 51 RSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDI----IPPSFRPFPAPGPQI 147
+ KY +F Q+ K G L G + R ++ + LP +L +IW LSDID +G L+ EF ++ +L +G+ +P LP ++ IP S P GP +
Sbjct: 134 KRKYDILFDQL-KPVDGKLMGDKVRQIMMGSKLPMPILGRIWDLSDIDKDGLLTRYEFTIAMHLIYRTLQGDSIPEDLPEELSENKIPKSLSAIPNLGPSV 233
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000011859 (supercontig:LSalAtl2s:LSalAtl2s832:43213:68821:1 gene:EMLSAG00000011859 transcript:EMLSAT00000011859 description:"augustus_masked-LSalAtl2s832-processed-gene-0.4") HSP 1 Score: 72.7886 bits (177), Expect = 1.867e-13 Identity = 42/109 (38.53%), Postives = 62/109 (56.88%), Query Frame = 0
Query: 34 GTPGSTAGGAWN--IAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPF 140
G G AG N I E R KY IF ++D G + G A+ ++++ LP NVL +IW LSD+ +G L +EF ++ +L ++ G LP +LP+ +IPPS R F
Sbjct: 431 GGEGINAGVGENDWIIEKDRYKYDEIFEKLDPVD-GKITGSAAKQEMVRSKLPNNVLGKIWKLSDVXRDGMLDVEEFALAMHLMNVKLDGHDLPIELPTHLIPPSKRGF 538
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000007473 (supercontig:LSalAtl2s:LSalAtl2s429:287998:291734:-1 gene:EMLSAG00000007473 transcript:EMLSAT00000007473 description:"maker-LSalAtl2s429-snap-gene-2.16") HSP 1 Score: 67.3958 bits (163), Expect = 4.407e-12 Identity = 62/251 (24.70%), Postives = 118/251 (47.01%), Query Frame = 0
Query: 599 EVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWW-TGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEA----SAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL---EAKEGVGPAKDLGNVE-ALFDYEGARSDELSFKQGDIIELLSKE--DGDWWRGK-LETESGMFPCNYVKEV 837
+ +A Y + +L +++ +L + WW + G PSNYV E + + + G + + + P S A++ +P IKP KD ++ A ++LSL +G I+I +K+ GWW+G+ G K IGWFP++Y + +A A+++ ++ +L++++ ELSF++GD +E+L + D DW++ + + + G+ P NY+ E+
Sbjct: 9 QYVMAKYDYVAQGNQELDMRRNERLLLLDDSKHWWRVSNSRHQTGYIPSNYVRREKPSIFDSIKKKVKGNNTSNSSNSRTLPSSSTSASHQNAGSP-------IKP--CSKDPIGEPIS------SAIQLDELSLVKGARILILEKSGDGWWRGQ-HGNK-----IGWFPSNYTQEELGDDAAHTYCMAENILDIMVSLYNFKAQNDTELSFEKGDRLEILDRPACDPDWYKARNTQGQIGLVPKNYLIEL 238
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000007748 (supercontig:LSalAtl2s:LSalAtl2s450:397890:414341:1 gene:EMLSAG00000007748 transcript:EMLSAT00000007748 description:"augustus_masked-LSalAtl2s450-processed-gene-3.3") HSP 1 Score: 65.4698 bits (158), Expect = 4.287e-11 Identity = 58/201 (28.86%), Postives = 90/201 (44.78%), Query Frame = 0
Query: 571 PSVILSVNPDEEEVNTDELVLPTDSLP---TEVFVAHVPYQSTE----PGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNY--VVPEGE------AGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQM--IIIRKKADSGWWQGEVQGGKG 754
P +I P+E D + + DSLP V + P Q E D++ G+ WW G + K GVFPSN+ V+ + E N E PP ++ + + +++ P+ +S+ PR+ PK VK E V PYEA + ++L+L G++ II + D GWW+GE+ G G
Sbjct: 173 PQIIDLDIPNELNDKKDIINMKKDSLPRVTCRVLFTYSPVQEDELELNINDIIECSGEA------EDGWWKGNLNGKFGVFPSNFVEVIHQKEEQQVADKNKRNKELHPPNQA-ISGLGNILNQNQEIEVPSGRGDSSIPRLPPKPVK------EQCVVQFPYEAQNEDELTLGEGRVVNIISKDSEDKGWWRGELDGKIG 360
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000010366 (supercontig:LSalAtl2s:LSalAtl2s688:204628:207074:1 gene:EMLSAG00000010366 transcript:EMLSAT00000010366 description:"maker-LSalAtl2s688-snap-gene-1.33") HSP 1 Score: 62.003 bits (149), Expect = 4.025e-10 Identity = 42/138 (30.43%), Postives = 67/138 (48.55%), Query Frame = 0
Query: 9 VNTVTPALSHAPVPVVLPVSSAASVGTP-------GSTAGGA---WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPS 136
+ T+ PA ++ P+ + V +P G G W I +R+KY IF ++ G + G A+ ++++ LP VLA+IW L+D D +G L DEF ++ +L + G L LP +IPPS
Sbjct: 370 LMTIVPADANEPLITGGAFNDVKDVNSPFGYKKCEGVDLGAGEPEW-IVNKSRAKYDAIFKELSPIN-GKITGSSAKKEMVKSRLPNPVLAKIWRLADXDQDGALDSDEFALAMHLIHVKLDGFDLTDDLPEHLIPPS 505
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000001912 (supercontig:LSalAtl2s:LSalAtl2s132:592485:593541:1 gene:EMLSAG00000001912 transcript:EMLSAT00000001912 description:"maker-LSalAtl2s132-snap-gene-6.37") HSP 1 Score: 59.6918 bits (143), Expect = 9.715e-10 Identity = 23/53 (43.40%), Postives = 34/53 (64.15%), Query Frame = 0
Query: 785 VEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVKEV 837
V A+++Y + DELSF G II +L K D WW G ++ +G+FP NYV+ +
Sbjct: 251 VTAIYEYAADKEDELSFSDGSIIYVLKKNDDGWWEGXMDGXTGLFPGNYVESI 303
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000003032 (supercontig:LSalAtl2s:LSalAtl2s1723:14160:15731:-1 gene:EMLSAG00000003032 transcript:EMLSAT00000003032 description:"maker-LSalAtl2s1723-augustus-gene-0.9") HSP 1 Score: 56.9954 bits (136), Expect = 7.531e-9 Identity = 26/53 (49.06%), Postives = 35/53 (66.04%), Query Frame = 0
Query: 787 ALFDYEGARSDELSFKQGDIIELLSKE-----DGDWWRGKLETESGMFPCNYV 834
A++DYE DEL+ ++GD IE+LSK+ D WW GK E G+FPCN+V
Sbjct: 57 AVYDYEAQGEDELTLEKGDTIEVLSKDYLISGDEGWWTGKCEGSVGVFPCNFV 109
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000002615 (supercontig:LSalAtl2s:LSalAtl2s1520:38908:44761:1 gene:EMLSAG00000002615 transcript:EMLSAT00000002615 description:"maker-LSalAtl2s1520-augustus-gene-0.15") HSP 1 Score: 57.3806 bits (137), Expect = 1.477e-8 Identity = 28/67 (41.79%), Postives = 40/67 (59.70%), Query Frame = 0
Query: 70 GGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPS 136
G I + L T L + LA+IW LSD D +G L+ +E+ ++ YL + KG+ LP LP +IPPS
Sbjct: 658 GNIVRKEFLSTTKLHKGTLARIWILSDYDQDGFLNKNEYCLAMYLIECKLKGKDLPHTLPHFLIPPS 724
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000012435 (supercontig:LSalAtl2s:LSalAtl2s911:83261:88220:1 gene:EMLSAG00000012435 transcript:EMLSAT00000012435 description:"maker-LSalAtl2s911-snap-gene-0.8") HSP 1 Score: 56.225 bits (134), Expect = 2.856e-8 Identity = 30/71 (42.25%), Postives = 41/71 (57.75%), Query Frame = 0
Query: 67 GFLGGIQARNTLLQ-TGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPS 136
G L G R L T L + LA+IW LSD D +G L+ +E+ ++ YL + KG+ LP LP +IPPS
Sbjct: 467 GKLSGSMVRKEFLSSTKLHKETLARIWILSDYDQDGFLNKNEYCLAMYLIECKLKGKDLPHTLPQFLIPPS 537
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|20138538|sp|O42287.1|ITSN1_XENLA (RecName: Full=Intersectin-1) HSP 1 Score: 267.7 bits (683), Expect = 2.755e-74 Identity = 260/968 (26.86%), Postives = 405/968 (41.84%), Query Frame = 0
Query: 27 VSSAASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVS---------------PSTFEDKRRENFNKGQAELEKRRQSIVDQQKREADERKKKEAAEAVEKEKQRQ----------------------------------------ELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKM-----------------NKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNG-----EQITEFEFRRNEKKKKVEQTQKLLEEMKEKF-------------ETIK-GEKEAKRESLDGHK-ESLIQIIEACKTLYDSFD-------------------------EKRREIKAEKSKRMRELTDPDHA-----WGNEEPEPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDP-SALEAIAAEEVETDIVAKVIVDWTGEDSFSMVKGAEIIVIGRPTEEWC-FGKVKDT-----------EACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVF-----------VAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQ--LSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYV--KLLEAKEGVGPAKDLGN----VEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLET-----ESGMFPCNYVK 835
+ A S P W + +R KY +F DK+ G L G QAR L+Q+ LPQ+ LA IW LSDID +GKL+ +EFI++ +L D+A G+PLP LP + IPPSFR +GS +S S + + P TFEDK+RENF +G ELEKRRQ++++QQ++E + + E AE KE++RQ ELERQR +EWE NR++EL + R EQE ++ LKAK+ ++ +++ D+ + ++ + R + + I++ SR+ ++ KM KQ L DQ +++ + + + + + K AL ++ G +Q+ E E K ++++ L+E++E + E IK E E K LD K E +++E K D EK+ EI+ + +K + +P W N E P++ V ALY F+ + DE+ + GD I+V ++ EPGWLGGE GK GWFP + P S + ET V V + S V A + W F T + PS+ + + + T S P+ V A P+++ + L F + I VL + WW G+ + G FP +YV P + S ++S + + PA+ ++P KP ++ + ++ Y S EQ L+ +G +I++ KK D WW G V G+K G FP++YV K EA G LG + + Y ++L+ G +I + K G WW G+L+ + G FP NYVK
Sbjct: 197 LQKAQSFDVPAPPLVVEWAVPSSSRLKYRQLFNSQDKTMSGNLTGPQARTILMQSSLPQSQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPILPPEYIPPSFRRV---------RSGSGLSIMSSVSVDQRLPEEPEEEEPQNADKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQDQERKRQQDLEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRHEIESTNKSRELRIAEITHLQQQLQESQQLLGKMIPEKQSLIDQLKQVQQNSLHRDSLLTLKRALETKEIGRQQLRDQLDEVEKETRAKLQEIDVFNNQLKELRELYNKQQFQKQQDFETEKIKQKELERKTSELDKLKEEDKRRMLEQDKLWQDRVKQEEERYKFQDEEKEKREESVQKCEVEKKPEIQEKPNKPFHQPPEPGKLGGQIPWMNTEKAPLTINQGDVKVVYYRALYPFDARSHDEITIEPGDIIMVDESQTGEPGWLGGELKGKTGWFPANYAERMPESEFPSTTKPAAETTAKPTVHV------APSPVAPAAFTNTSTNSNNWADFSSTWPTNNTDKVESDNWDTWAAQPSLTVPSAGQHRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYV---KLISGP-----------LRKSTSIDSTSSES--PASLKRVSSPAFKP--------AIQGEEYISMYTYESNEQGDLTFQQGDLIVVIKK-DGDWWTGTV----GEK--TGVFPSNYVRPKDSEAAGSGGKTGSLGKKPEIAQVIASYAATAPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1118 HSP 2 Score: 177.563 bits (449), Expect = 1.734e-44 Identity = 122/371 (32.88%), Postives = 176/371 (47.44%), Query Frame = 0
Query: 490 GGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGE-DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPS--VILSVNPDEEEVNTDELV------LPTDSLPT-------EVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEG----VGPAKDLG-----NVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
G+ ++ + P T PS + E+VE + A+ + W + D+ ++I + + W FG+V+ + G+FP V L P + + D L S P E +++ Y+S E GDL F++G I V+ K+ +WWTG +K GVFPSNYV P+ A + K K E+A+V+A Y AT+ EQL+L GQ+I+IRKK GWW+GE+Q +GKKRQIGWFPA+YVKLL P K V ++DY DEL+F +G +I +L+KED DWW+G+L G+FP NYVK
Sbjct: 868 AGQHRQRSAFTPATVTGSSPSPVLG-QGEKVE-GLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQK--GWFPKSYVKLISGPLRKSTSIDSTSSESPASLKRVSSPAFKPAIQGEEYISMYTYESNEQGDLTFQQGDLIVVIKKDGDWWTGTVGEKTGVFPSNYVRPKDSEAAGSG---------------------------------------GKTGSLGKKPEIAQVIASYAATAPEQLTLAPGQLILIRKKNPGGWWEGELQA-RGKKRQIGWFPANYVKLLSPGTNKSTPTEPPKPTSLPPTCQVIGMYDYIAQNDDELAFSKGQVINVLNKEDPDWWKGELNGHVGLFPSNYVK 1194 HSP 3 Score: 82.8037 bits (203), Expect = 8.381e-15 Identity = 42/103 (40.78%), Postives = 60/103 (58.25%), Query Frame = 0
Query: 31 ASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDII 133
A GTP W I R+K+ F + K G++ G QARN LQ+GLPQ VLAQIW L+D++ +G++ EF ++ L L +G PLP LPS+++
Sbjct: 2 AQFGTPFGGNLDIWAITVEERAKHDQQFHGL-KPTAGYITGDQARNFFLQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYPLPSILPSNML 103 HSP 4 Score: 72.4034 bits (176), Expect = 1.180e-11 Identity = 56/209 (26.79%), Postives = 96/209 (45.93%), Query Frame = 0
Query: 453 EAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDI-----VAKVIVDW--TGEDSFSMVKGAEIIVIGRPTEEWCFGKVK---DTEACGFFPS-VILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVK-NSEWWTGQYDDKLGVFPSNYV 649
E ++Y +E + + +L F+ GD I+V K + W G K G FP +V P EA + + +A+VI + T + ++ G I++ + W G+++ G+FP+ + ++P + E PT PT + Y + +L F +GQ I VL K + +WW G+ + +G+FPSNYV
Sbjct: 990 EYISMYTYESNEQGDLTFQQGDLIVVIKK---DGDWWTGTVGEKTGVFPSNYVR--PKDSEAAGSGGKTGSLGKKPEIAQVIASYAATAPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTNKSTPTEPPKPTSLPPTCQVIGMYDYIAQNDDELAFSKGQVINVLNKEDPDWWKGELNGHVGLFPSNYV 1193
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|20138462|sp|Q9WVE9.1|ITSN1_RAT (RecName: Full=Intersectin-1; AltName: Full=EH domain and SH3 domain regulator of endocytosis 1) HSP 1 Score: 260.381 bits (664), Expect = 7.921e-72 Identity = 277/1012 (27.37%), Postives = 426/1012 (42.09%), Query Frame = 0
Query: 8 PVNTVTPALSHAPVPVVLPVSSAASVGTPGSTAGGAWN-----------------IAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPF---PAPGPQIVSTAGSTVSTPGSSRAESVVS---PSTFEDKRRENFNKGQAELEKRRQSIVDQQKREADERKKKEAAEAVEKEKQRQ----------------------------------------ELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNAL-----------------KQQLKDQNERLLKVTQEKAQMESKKAA-----LASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKE--------KFETIKGE----KEAKRESLDGHK---ESLIQIIEACKTLY-----------------------DSFDEKRREIKA-----EKSKRM----RELTDPDHA-WGNEEPEPVSAGGDSSDAVEAY-ALYDFEPSNEDELAFKTGDKIIVH-----KNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGEDSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTD------ELVLP----------------TDSLPTEVF-----------VAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVGPAKDLGNVE-------ALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLET-----ESGMFPCNYVK 835
PV PA +H LP SS+ S PGS + + +R KY +F DK+ G L G QAR L+Q+ LPQ LA IW LSDID +GKL+ +EFI++ +L D+A G+PLP LP + IPPSFR S+A + SS E V P TFEDK+RENF +G ELEKRRQ++++QQ++E + + E AE KE++RQ ELERQR +EWE NR++EL + R +QE ++ LKA++ ++ +++ D+ + ++ + R +A + I++ SR+ ++ ++ L KQ L DQ +++ + + + + + K A LA Q EQ+ E E K ++++ L+E++E K +I+ E KE +R+SL+ K E ++ E K DS +K E +A +K R+ +E P A W E P++ S V Y ALY FE + DE+ + GD ++V ++ EPGWLGGE GK GWFP + E I E+ T AK + D T + + + + E + +PS S N E N D L +P T S P+ V A P+++ + L F + I VL + WW G+ + G FP +YV + P +S + P E+ P++ +P KP ++ M YE++ L+ +G +I++ KK D WW G V G FP++YV+L ++ EG G A G++E + Y ++L+ G +I + K G WW G+L+ + G FP NYVK
Sbjct: 164 PVIQPLPAFAHPAA--TLPKSSSFSRSGPGSQLNTKLQKAQSFDVASAPAAAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSSSADQRLPEEPSSEDEQQVEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLTQRNKDQEGIVVLKARRKTLEFELEALNDKKHQLEGKLQDIRCRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLREQLDEVEKETRSKLQEIDVFNNQLKELREIHSKQQLQKQRSIEAERLKQKEQERKSLELEKQKEEGQRRVQERDKQWQEHVQQEEQQRPRKPHEEDKLKREDSVKKKEAEERAKPEVQDKQSRLFHPHQEPAKPAQAPWPTTEKGPLTISAQESAKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGEPKGKTGWFPANYA-------EKIPENEIPTP--AKPVTDLTSAPAPKLALRETPAPLPVTSSEPSTTPNNWADFSSTWPS---STNEKPETDNWDTWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQKGWFPKSYV---------KLISGPVRKSTSIDTGPTEA-------PSSLKRVASPAAKPAIPGEEFVAMYT------YESSEHGDLTFQQGHVIVVTKK-DGDWWTGTVGETSGV------FPSNYVRLKDS-EGSGTAGKTGSLEKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1131 HSP 2 Score: 191.815 bits (486), Expect = 5.039e-49 Identity = 125/373 (33.51%), Postives = 181/373 (48.53%), Query Frame = 0
Query: 490 GGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGE-DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFP-------------SVILSVNPDEEEVNTDELVLPT--DSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEA-----------KEGVGPAKDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
G+ ++ + P T PS + E+VE + A+ + W + D+ +++I + + W FG+V+ + G+FP S + P E + + P ++P E FVA Y+S+E GDL F++G I V K+ +WWTG + GVFPSNYV + G+ A K +K E+A+V+A Y AT EQL+L GQ+I+IRKK GWW+GE+Q +GKKRQIGWFPA+YVKLL K V PA + V ++DY DEL+F +G II +LSKED DWW+G++ + G+FP NYVK
Sbjct: 881 AGQLRQRSAFTPATATGSSPSPVLG-QGEKVE-GLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQK--GWFPKSYVKLISGPVRKSTSIDTGPTEAPSSLKRVASPAAKPAIPGEEFVAMYTYESSEHGDLTFQQGHVIVVTKKDGDWWTGTVGETSGVFPSNYVRLKDSEGSGTA---------------------------------------GKTGSLEKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQA-RGKKRQIGWFPANYVKLLSPGTSKITPTELPKTAVQPA--VCQVIGMYDYTAQNDDELAFSKGQIINVLSKEDPDWWKGEVSGQVGLFPSNYVK 1207 HSP 3 Score: 72.0182 bits (175), Expect = 1.610e-11 Identity = 40/99 (40.40%), Postives = 54/99 (54.55%), Query Frame = 0
Query: 31 ASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLP 129
A TP + W I R+K+ F Q K GF+ G QARN Q+GLPQ VLAQIW L+D++ +G++ EF ++ L L +G LP LP
Sbjct: 2 AQFPTPFGGSLDIWAITVEERAKHDQQF-QSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNKDGRMDQVEFSIAMKLIKLKLQGYQLPPALP 99 HSP 4 Score: 70.8626 bits (172), Expect = 3.434e-11 Identity = 55/209 (26.32%), Postives = 96/209 (45.93%), Query Frame = 0
Query: 453 EAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDI---VAKVIVDWT--GEDSFSMVKGAEIIVIGRPTEEWCFGKVK---DTEACGFFPS-VILSVNPDEEEVNTDELVLPTDSLPTEV--FVAHVPYQSTEPGDLVFEEGQKIRVLVK-NSEWWTGQYDDKLGVFPSNYV 649
E A+Y +E S +L F+ G I+V K + W G +G FP +V S A + + +A+VI +T G + ++ G I++ + W G+++ G+FP+ + ++P ++ EL P ++ V + Y + +L F +GQ I VL K + +WW G+ ++G+FPSNYV
Sbjct: 1003 EFVAMYTYESSEHGDLTFQQGHVIVVTKK---DGDWWTGTVGETSGVFPSNYVRLKDSEGSGTAGKTGSLEKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEL--PKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLSKEDPDWWKGEVSGQVGLFPSNYV 1206
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|294862445|sp|Q9Z0R6.2|ITSN2_MOUSE (RecName: Full=Intersectin-2; AltName: Full=EH domain and SH3 domain regulator of endocytosis 2; Short=EH and SH3 domains protein 2; AltName: Full=SH3 domain-containing protein 1B) HSP 1 Score: 227.254 bits (578), Expect = 1.553e-60 Identity = 240/900 (26.67%), Postives = 396/900 (44.00%), Query Frame = 0
Query: 39 TAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVS-PSTFEDKRRENFNKGQAELEKRRQSIVDQQKREAD----------ERKKKEAAE-----AVEKEKQ-------------------------RQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQM-ESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKT-------LYDSFDEKRREIKA------------------------------------EKSKRMRELTDPDHAWGNEEPEPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGEDSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYV--VP--EGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTE--QLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVGPAKDLGN-------VEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLET-----ESGMFPCNYVK 835
T W + + +R KY F +DK G+L G QARN LLQ+ L Q LA IWTL+DIDG+G+L +EFI++ +L D+A G+PLP LP +++PPSFR G Q+ S G+ S + E P TFEDKR+ N+ +G ELEKRRQ +++QQ+REA+ ERK++E E +E EK+ +QELERQR +EWE R++EL S + EQE +++L +++ ++ +++ + + I+ + + + K+ ++ + D ++ ++ L+Q+LK+ +L+ + EK + E K S T I+ + +EK ++L + +KE+ + ++ E +K +D L ++ E+ T L+ +K +EI+ EK KR++E D E +S V ALY FE N DE++F +GD I V + EPGWL G F GK GWFP +V S+ +A++ ++ + T + V + T + + K P + ++ + V ++L + + + + + L F + I VL + WW G+ G FP +YV +P E + G P A + + PV S A P V +D +A Y +S E L+ T G+ I++ +K D WW G + + G FP++YV+ + +E G A G + Y + +++LS G +I +L K WW+G+L+ + G FP ++VK
Sbjct: 234 TGTSEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFR----GGKQVDSVNGTLPSYQKTQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQVLMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKEIERREAAKQELERQRRLEWERLRRQELLSQKTREQEDIVRLSSRKKSLHLELEAVNGKHQQISGRLQDVQIRKQTQKTELEVLDKQCDLEIMEIKQLQQELKEYQNKLIYLVPEKQLLNERIKNMQLSNTPDSGISLLHKKSSEK-------EELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRESYNTQQLALEQLHKIKRDKLKEIERKRLEQIQKKKLEDEAARKAKQGKENLWRESIRKEEEEKQKRLQEEKSQDKTQEEERKAEAKQSETASALVNYRALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVEKVLSSEKALSPKKALLPPTVSLSATSTSSQPPASVTDYHNVSFSNLTVNTTWQQ-KSAFTRTVSPGSVSPIHGQGQAV---------ENLKAQALCS---WTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGRGWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTS--TAYP-----------------VGED--------YIALYSYSSVEPGDLTFTEGEEILVTQK-DGEWWTGSI------GERTGIFPSNYVR-PKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1074 HSP 2 Score: 187.578 bits (475), Expect = 1.484e-47 Identity = 121/351 (34.47%), Postives = 174/351 (49.57%), Query Frame = 0
Query: 506 TYDPSALEAIAAE-EVETDIVAKVIVDWTG--EDSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEE----------------EVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL-EAKEGVGPA-KDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
T P ++ I + + ++ A+ + WT E+ + K ++I + E W FG+V G+FP + + P E +T V T E ++A Y S EPGDL F EG++I V K+ EWWTG ++ G+FPSNYV P+ + NA +S A KP E+A+V + Y A+ TEQLSL GQ+I+I KK SGWWQGE+Q +GKKRQ GWFPAS+VKLL + E P + V A++DY DEL+F +G +I +++K+D DWW+G+ +G+FP NYVK
Sbjct: 836 TVSPGSVSPIHGQGQAVENLKAQALCSWTAKKENHLNFSK-HDVITVLEQQENWWFGEVHGGR--GWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGERTGIFPSNYVRPKDQENFGNA-----------------------------SKSGASNKKP----------EIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQA-RGKKRQKGWFPASHVKLLGPSSERTMPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLTGLFPSNYVK 1143 HSP 3 Score: 78.1814 bits (191), Expect = 1.834e-13 Identity = 87/359 (24.23%), Postives = 141/359 (39.28%), Query Frame = 0
Query: 441 PVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTY---------DPSALEAIAAEEVE------TDIVAKVIVDWTGEDSFSMVKGAEI-------IVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKN-SEWWTGQYDDK-----LGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYE--ATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKL 769
P+ G + + ++A AL + E+ L F D I V L+ + W GE +G GWFP+++V +P AL A ++ T V D+ S+S V+ ++ I++ + EW G + E G FPS V P ++E + + E+ Y ++ L GQ I +L KN S WW G+ + G FP+++V G P++E P V +V+A Y+ A + ++L+ ++GQ+I + K D WWQGE G G FP++YVK+
Sbjct: 844 PIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITV---LEQQENWWFGEVHGGRGWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWTGSI--GERTGIFPSNY--VRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLG----PSSERTMPTFHAV-----------------------------------------CQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNG------LTGLFPSNYVKM 1144 HSP 4 Score: 72.0182 bits (175), Expect = 1.448e-11 Identity = 42/108 (38.89%), Postives = 59/108 (54.63%), Query Frame = 0
Query: 36 PGSTAGG--AWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDI-IPPSFRPF 140
P + GG W I R+K+ F + S G++ G QAR LQ+GLP VLA+IW LSD++ +GK+ EF ++ L L +G+ LP LP + PP F P
Sbjct: 6 PTAMNGGPNMWAITSEERTKHDKQFDNLKPSG-GYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 112
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|408360155|sp|Q9Z0R4.2|ITSN1_MOUSE (RecName: Full=Intersectin-1; AltName: Full=EH and SH3 domains protein 1) HSP 1 Score: 219.55 bits (558), Expect = 5.609e-58 Identity = 193/663 (29.11%), Postives = 299/663 (45.10%), Query Frame = 0
Query: 8 PVNTVTPALSHAPVPVVLPVSSAASVGTPGSTA-----------------GGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGST-------VSTPGSSRAESVVSPSTFEDKRRENFNKGQAELEKRRQSIVDQQKREADERKKKEAAEAVEKEKQRQ----------------------------------------ELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNAL-----------------KQQLKDQNERLLKVTQEKAQMESKKAA-----LASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKE--------KFETIKG----EKEAKRESLDGHKE---SLIQIIEACKTLYDSFDEKRR----------EIKAEKSKRMRE---------------LTDPDH---------AWGNEEPEPVSAGGDSSDAVEAY-ALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTG 534
PV PA +H LP SS+ S PGS W + + +R KY +F DK+ G L G QAR L+Q+ LPQ LA IW LSDID +GKL+ +EFI++ +L D+A G+PLP LP + IPPSFR + V ++ S S+ + E + P TFEDK+RENF +G ELEKRRQ++++QQ++E + + E AE KE++RQ ELERQR +EWE NR++EL + R EQE + LKA++ ++ +++ D+ + ++ + R +A + I++ SR+ ++ ++ L KQ L DQ +++ + + + + + K A LA Q EQ+ E E K ++++ L+E++E K +++ +KE +R+SL+ K+ + ++ E K + ++ + +K E S R +E L P W E P++ S V Y ALY FE + DE+ + GD ++V ++ EPGWLGGE GK GWFP + E I EV T AK + D T
Sbjct: 164 PVIQPLPAFAHPAA--TLPKSSSFSRSGPGSQLNTKLQKAQSFDVASAPPAAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSSSVDQRLPEEPSSEDEQQPEKKL-PVTFEDKKRENFERGSVELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEGTVVLKARRKTLEFELEALNDKKHQLEGKLQDIRCRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLREQLDEVERETRSKLQEIDVFNNQLKELREIHSKQQLQKQRSLEAARLKQKEQERKSLELEKQKEDAQRRVQERDKQWLEHVQQEEQPRPRKPHEEDRLKREDSVRKKEAEERAKPEMQDKQSRLFHPHQEPAKLATQAPWSTTEKGPLTISAQESVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYA-------EKIPENEVPTP--AKPVTDLTS 814 HSP 2 Score: 192.2 bits (487), Expect = 4.961e-49 Identity = 125/373 (33.51%), Postives = 181/373 (48.53%), Query Frame = 0
Query: 490 GGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGE-DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFP-------------SVILSVNPDEEEVNTDELVLPT--DSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEA-----------KEGVGPAKDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
G+ ++ + P T PS + E+VE + A+ + W + D+ +++I + + W FG+V+ + G+FP S + P E + + P ++P E F+A Y+S+E GDL F++G I V K+ +WWTG DK GVFPSNYV + G+ A K K E+A+V+A Y AT EQL+L GQ+I+IRKK GWW+GE+Q +GKKRQIGWFPA+YVKLL K V PA + V ++DY DEL+F +G II +L+KED DWW+G++ + G+FP NYVK
Sbjct: 877 AGQLRQRSAFTPATATGSSPSPVLG-QGEKVE-GLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQK--GWFPKSYVKLISGPVRKSTSIDTGPTESPASLKRVASPAAKPAIPGEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWTGTVGDKSGVFPSNYVRLKDSEGSGTA---------------------------------------GKTGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQA-RGKKRQIGWFPANYVKLLSPGTSKITPTELPKTAVQPA--VCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQVGLFPSNYVK 1203 HSP 3 Score: 102.449 bits (254), Expect = 6.643e-21 Identity = 101/379 (26.65%), Postives = 161/379 (42.48%), Query Frame = 0
Query: 423 RMRELTDPDHAWGNEEPEPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFV-----------------TYDPSALEAIAAEEVETDIVA-KVIVDWTGEDS----FSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHV--PYQSTEPGDLVFEEGQKIRVLVKN-SEWWTGQYDDK-----LGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATST--EQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKL 769
R R P A G+ P PV G+ + ++A ALY + ++ L F D I V L+ + W GE G+ GWFP+++V T P++L+ +A+ + I + I +T E S + +G ++IV+ + +W G V D G FPS + + E + T SL + +A V Y +T P L GQ I + KN WW G+ + +G FP+NYV + PG S +I P ++ K + +V+ Y+ T+ ++L+ ++GQ+I + K D WW+GEV G Q+G FP++YVKL
Sbjct: 881 RQRSAFTPATATGSS-PSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITV---LEQQDMWWFGEVQGQKGWFPKSYVKLISGPVRKSTSIDTGPTESPASLKRVASPAAKPAIPGEEFIAMYTYESSEQGDLTFQQG-DVIVVTKKDGDWWTGTVGD--KSGVFPSNYVRLKDSEGSGTAGK----TGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV-----------KLLSPGTS---------------------------KITPTELPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSG------QVGLFPSNYVKL 1204 HSP 4 Score: 75.485 bits (184), Expect = 1.601e-12 Identity = 39/99 (39.39%), Postives = 54/99 (54.55%), Query Frame = 0
Query: 31 ASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLP 129
A TP + W I R+K+ F + K GF+ G QARN Q+GLPQ VLAQIW L+D++ +G++ EF ++ L L +G LP LP
Sbjct: 2 AQFPTPFGGSLDVWAITVEERAKHDQQFLSL-KPIAGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSTLP 99
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|116242596|sp|Q15811.3|ITSN1_HUMAN (RecName: Full=Intersectin-1; AltName: Full=SH3 domain-containing protein 1A; AltName: Full=SH3P17) HSP 1 Score: 208.764 bits (530), Expect = 2.205e-54 Identity = 179/646 (27.71%), Postives = 287/646 (44.43%), Query Frame = 0
Query: 8 PVNTVTPALSHAPVPVVLPVSSAASVGTPGSTAG-----------------GAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGST--------VSTPGSSRAESVVSPSTFEDKRRENFNKGQAELEKRRQSIVDQQKREADERKKKEAAEAVEKEKQRQ----------------------------------------ELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKM---------------------------------NAL------------------KQQLKDQNERLLKVTQEKAQ----MESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDG-------------HKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTDP-----DHAWGNEEPEPVSAGGDSSDAVEAY-ALYDFEPSNEDELAFKTGDKIIVH-----KNLDPEPGWLGGEFNGKAGWFPETFVTYDP 509
PV PA +H LP SS+ S PGS W + + +R KY +F DK+ G L G QAR L+Q+ LPQ LA IW LSDID +GKL+ +EFI++ +L D+A G+PLP LP + IPPSFR + V ++ S V + E + P TFEDK+RENF +G ELEKRRQ++++QQ++E + + E AE KE++RQ ELERQR +EWE NR++EL + R EQE ++ LKAK+ ++ +++ D+ + ++ + R + + I++ SR+ ++ ++ N+L +Q L+DQ + + K T+ K Q ++ L N +Q+ + + E+ K+ EQ +K++E K+K E + +E ++ L+ H+E ++ E+ K ++ ++E + + + + +P W E P++ + V Y ALY FE + DE+ + GD ++V ++ EPGWLGGE GK GWFP + P
Sbjct: 164 PVIQPLPAFAHPAA--TLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKL-PVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGE-EKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIP 805 HSP 2 Score: 180.644 bits (457), Expect = 2.218e-45 Identity = 123/371 (33.15%), Postives = 179/371 (48.25%), Query Frame = 0
Query: 490 GGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGE-DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPS--VILSVNPDEEEVNTD----------ELVLPTDSLPT---EVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLE-AKEGVGPAKD--------LGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
G+ ++ + P T PS + E+VE + A+ + W + D+ ++I + + W FG+V+ + G+FP V L P + + D + V + P E F+A Y+S+E GDL F++G I V K+ +WWTG DK GVFPSNYV + G+ A K K E+A+V+A Y AT EQL+L GQ+I+IRKK GWW+GE+Q +GKKRQIGWFPA+YVKLL + P + + V ++DY DEL+F +G II +L+KED DWW+G++ + G+FP NYVK
Sbjct: 884 AGQLRQRSAFTPATATGSSPSPVLG-QGEKVE-GLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQK--GWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTA---------------------------------------GKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQA-RGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210 HSP 3 Score: 101.679 bits (252), Expect = 1.386e-20 Identity = 99/380 (26.05%), Postives = 160/380 (42.11%), Query Frame = 0
Query: 423 RMRELTDPDHAWGNEEPEPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFV-----------TYDPSALEAIAAEEVETDIVAKVIVDWTGEDSFSM------------VKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHV--PYQSTEPGDLVFEEGQKIRVLVKN-SEWWTGQYDDK-----LGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATST--EQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKL 769
R R P A G+ P PV G+ + ++A ALY + ++ L F D I V L+ + W GE G+ GWFP+++V + D + E+ A+ + AK +V +GE+ +M + ++I++ + +W G V D G FPS + + E + T SL + +A V Y +T P L GQ I + KN WW G+ + +G FP+NYV + PG S++ + P +S A + +V+ Y+ T+ ++L+ +GQ+I + K D WW+GEV G Q+G FP++YVKL
Sbjct: 888 RQRSAFTPATATGSS-PSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITV---LEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVV--SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGD--KAGVFPSNYVRLKDSEGSGTAGK----TGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV-----------KLLSPGTSKITPTEPPKSTALA---------------------------AVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNG------QVGLFPSNYVKL 1211 HSP 4 Score: 73.559 bits (179), Expect = 6.082e-12 Identity = 39/99 (39.39%), Postives = 54/99 (54.55%), Query Frame = 0
Query: 31 ASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLP 129
A TP + W I R+K+ F + K GF+ G QARN Q+GLPQ VLAQIW L+D++ +G++ EF ++ L L +G LP LP
Sbjct: 2 AQFPTPFGGSLDIWAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALP 99
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|294862505|sp|Q9NZM3.3|ITSN2_HUMAN (RecName: Full=Intersectin-2; AltName: Full=SH3 domain-containing protein 1B; AltName: Full=SH3P18; AltName: Full=SH3P18-like WASP-associated protein) HSP 1 Score: 200.675 bits (509), Expect = 7.754e-52 Identity = 125/344 (36.34%), Postives = 179/344 (52.03%), Query Frame = 0
Query: 506 TYDPSALEAIAAE-EVETDIVAKVIVDWTGE-DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDE---LVLPTDSLPT-------EVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL-EAKEGVGPA-KDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
T P ++ I + +V ++ A+ + WT + D+ +II + E W FG+V G+FP + + P E V +E L + PT E ++A PY S EPGDL F EG++I V K+ EWWTG D+ G+FPSNYV P+ + E+ A+N P E+A+V + Y A+ +EQLSL GQ+I+I KK SGWWQGE+Q +GKKRQ GWFPAS+VKLL + E PA + V A++DY DELSF +G +I +++K+D DWW+G++ +G+FP NYVK
Sbjct: 882 TVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGR--GWFPKSYVKIIPGSE-VKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQ----------------ESFGSASKSGASNKKP-----------------------EIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQA-RGKKRQKGWFPASHVKLLGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1182 HSP 2 Score: 159.073 bits (401), Expect = 1.891e-38 Identity = 131/417 (31.41%), Postives = 213/417 (51.08%), Query Frame = 0
Query: 39 TAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVS-PSTFEDKRRENFNKGQAELEKRRQSIVDQQKREAD----------ERKKKEAAE-----AVEKEKQ-------------------------RQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEK------KKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDS 408
T W + + TR KY F +DKS G+L G QARN LLQ+ L Q LA IWTL+D+DG+G+L +EFI++ +L D+A G+PLP LP +++PPSFR G QI S G+ S E P TFEDKR+ N+ +G ELEKRRQ++++QQ+REA+ ERK++E E +E EK+ +QELERQR +EWE R++EL + + EQE++++L +K+ N+ +++ + + I+ + + R K+ ++ + D ++ ++ L+Q+L++ +L+ + EK Q E+I +F KK + ++L + +KE+ + ++ E +K +D L C + DS
Sbjct: 233 TGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFR----GGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEK------------QLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQL-----KCGNMDDS 628 HSP 3 Score: 74.3294 bits (181), Expect = 2.799e-12 Identity = 43/108 (39.81%), Postives = 60/108 (55.56%), Query Frame = 0
Query: 36 PGSTAGG--AWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDI-IPPSFRPF 140
P + GG W I R+K+ F + S G++ G QARN LQ+GLP VLA+IW LSD++ +GK+ EF ++ L L +G+ LP LP + PP F P
Sbjct: 6 PTAMNGGPNMWAITSEERTKHDRQFDNLKPSG-GYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 112 HSP 4 Score: 66.6254 bits (161), Expect = 6.589e-10 Identity = 60/231 (25.97%), Postives = 101/231 (43.72%), Query Frame = 0
Query: 437 EEPEPVSAGGDSSDAVEAY-------ALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFV------TYDPSALEAIAAEEVETDIVAKVIVDWTGEDSFSMVKGAEIIVIGRPTEEWCFGKVK---DTEACGFFP-SVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNS-EWWTGQYDDKLGVFPSNYV 649
EEPE + A + AY ALY + +L F G++I+V + D E W G ++G FP +V ++ ++ + ++ E V V +G + S+ G I+++ + T W G+++ G+FP S + + P E P P +A Y + +L F +GQ I V+ K+ +WW G+ + G+FPSNYV
Sbjct: 962 EEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK-DGE--WWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVA-SGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERAT------PAFH-PVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV 1181
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|166977689|sp|Q91X43.2|SH319_MOUSE (RecName: Full=SH3 domain-containing protein 19; AltName: Full=Kryn) HSP 1 Score: 103.99 bits (258), Expect = 1.393e-21 Identity = 93/317 (29.34%), Postives = 148/317 (46.69%), Query Frame = 0
Query: 526 AKVIVDWTGE--DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDEL-VLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVK--NSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAK-EGVGPAKDLGN-VEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
A + D+ E D S+ G + ++ + EW GK ++ G FP+ + V D E + + + VA Y + +L F EG+ I +L + N EW G+ D+ G+FP N+V G+ P G + + P ++++ P +N +S+ P E K + + A ++E L RG I+I ++ DS W++G + +G FPA +V+ A+ +GV A G V+AL+D+ G DELSFK GD+I L D W RG+L +GMFP NYV+
Sbjct: 499 AVALHDFPAEQADDLSLTSGEIVYLLEKIDAEWYRGKCRNQ--TGVFPANYVKVIVDIPEGRSGKRESFSSHCAKGPRCVARFEYIGDQKDELSFSEGEVI-ILTEYVNEEWGRGEIRDRSGIFPLNFVELVGDH-------PTSGANILSTKVPPKTKNED--PGSNSQDSSPP-------------GEWCKALHSFTAETSEDLPFKRGDRILILERLDSDWYRGRLHDREG------IFPAVFVQPCPAEAKGVASAIPKGRKVKALYDFLGENEDELSFKAGDVITELEPIDDAWMRGELMGRAGMFPKNYVQ 784 HSP 2 Score: 75.0998 bits (183), Expect = 1.318e-12 Identity = 44/134 (32.84%), Postives = 72/134 (53.73%), Query Frame = 0
Query: 718 YEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL----EAKEGV----------GPAKDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVKEV 837
+ A + LSLT G+++ + +K D+ W++G+ + Q G FPA+YVK++ E + G GP A F+Y G + DELSF +G++I L + +W RG++ SG+FP N+V+ V
Sbjct: 505 FPAEQADDLSLTSGEIVYLLEKIDAEWYRGKC------RNQTGVFPANYVKVIVDIPEGRSGKRESFSSHCAKGP-----RCVARFEYIGDQKDELSFSEGEVIILTEYVNEEWGRGEIRDRSGIFPLNFVELV 627 HSP 3 Score: 67.0106 bits (162), Expect = 3.958e-10 Identity = 85/347 (24.50%), Postives = 138/347 (39.77%), Query Frame = 0
Query: 449 SDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAE-EVETDIVAK-----VIVDWTGE--DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFP--------------SVILSVNPDEEEVNTDELVLPTDSLPT-EVFVAHVPYQSTEPGDLVFEEGQKIRVLVK-NSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLE 771
S A A AL+DF D+L+ +G+ + + + +D E W G+ + G FP +V E + + E + AK ++ G+ D S +G II+ EEW G+++D G FP + ILS + N D DS P E A + + DL F+ G +I +L + +S+W+ G+ D+ G+FP+ +V P P E++ ASA + K K L + E ++LS G +I + D W +GE+ G + G FP +YV+ L+
Sbjct: 494 SGAPHAVALHDFPAEQADDLSLTSGEIVYLLEKIDAE--WYRGKCRNQTGVFPANYVKVIVDIPEGRSGKRESFSSHCAKGPRCVARFEYIGDQKDELSFSEGEVIILTEYVNEEWGRGEIRDR--SGIFPLNFVELVGDHPTSGANILSTKVPPKTKNEDPGSNSQDSSPPGEWCKALHSFTAETSEDLPFKRGDRILILERLDSDWYRGRLHDREGIFPAVFVQPC------------PAEAKGVASA---------------------------IPKGRKVKALYDFLGENE----DELSFKAGDVITELEPIDDAWMRGELMG------RAGMFPKNYVQFLQ 787 HSP 4 Score: 65.855 bits (159), Expect = 1.041e-9 Identity = 40/126 (31.75%), Postives = 67/126 (53.17%), Query Frame = 0
Query: 725 QLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEA--KEGVGPAKDLGNVE-----------ALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVKEV 837
+LS RG +++I K+A++ + E Q G+G G S +K++ + G D G+ + AL D+ ++D+LS G+I+ LL K D +W+RGK ++G+FP NYVK +
Sbjct: 432 ELSCKRGDVLVILKQAENNYL--ECQRGEG----TGRVHPSQMKIVTPLDERPRGRPNDSGHSQKPVDSGAPHAVALHDFPAEQADDLSLTSGEIVYLLEKIDAEWYRGKCRNQTGVFPANYVKVI 551
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|166977688|sp|Q5HYK7.2|SH319_HUMAN (RecName: Full=SH3 domain-containing protein 19; AltName: Full=ADAM-binding protein Eve-1; AltName: Full=EEN-binding protein; Short=EBP) HSP 1 Score: 98.2117 bits (243), Expect = 9.535e-20 Identity = 88/320 (27.50%), Postives = 145/320 (45.31%), Query Frame = 0
Query: 526 AKVIVDWTGE--DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPD-EEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVK---NSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVES--EDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL--EAKEGVGPAKDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
A V+ D+ E D ++ G + ++ + +W G ++ G FP+ + V D E N + + + VA Y + +L F EG+ I ++K N EW G+ + G+FP N+V P + P G + + P+++ ED+ SN+ + + E + + + A +++ LS RG I I ++ DS W +G +Q +G FPA +V+ EAK + +AL+D+ G DELSFK GDII L D DW G+L +SG+FP NY++
Sbjct: 500 AVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRN--QIGIFPANYVKVIIDIPEGGNGKRECVSSHCVKGSRCVARFEYIGEQKDELSFSEGEII--ILKEYVNEEWARGEVRGRTGIFPLNFV-------EPVEDYPTSGANVLSTKVPLKTKKEDSG---------SNS--------QVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREG------IFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQ 785 HSP 2 Score: 78.5666 bits (192), Expect = 1.060e-13 Identity = 44/135 (32.59%), Postives = 75/135 (55.56%), Query Frame = 0
Query: 712 AKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVK-LLEAKEGVGPAKDL--------GNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVKEV 837
A V+ + A + L+LT G+++ + +K D+ W++G + QIG FPA+YVK +++ EG ++ A F+Y G + DELSF +G+II L + +W RG++ +G+FP N+V+ V
Sbjct: 500 AVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNC------RNQIGIFPANYVKVIIDIPEGGNGKRECVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPV 628 HSP 3 Score: 69.707 bits (169), Expect = 5.972e-11 Identity = 89/371 (23.99%), Postives = 147/371 (39.62%), Query Frame = 0
Query: 429 DPDHAWGNEEPEPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTY-------DPSALEAIAAEEVE-TDIVAKVIVDWTGE--DSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPT-----------------DSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVK-NSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLE 771
DP HA +PV +G A A L+DF D+L +G+ + + + +D + W G + G FP +V E +++ V+ + VA+ ++ GE D S +G II+ EEW G+V+ G FP + V P E+ + VL T +SLP E A + + DL F+ G +I++L + +S+W G+ D+ G+FP+ +V P P E++ I PK K AK + + + ++LS G +I + D W GE+ G + G FP +Y++ L+
Sbjct: 485 DPSHAQ-----KPVDSG-----APHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTD--WYRGNCRNQIGIFPANYVKVIIDIPEGGNGKRECVSSHCVKGSRCVAR--FEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGR--TGIFP--LNFVEPVEDYPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRP----------------------CPAEAKSML-------------AIVPKGRK--------AKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMG------KSGIFPKNYIQFLQ 788
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|61223942|sp|Q9UBC2.1|EP15R_HUMAN (RecName: Full=Epidermal growth factor receptor substrate 15-like 1; AltName: Full=Eps15-related protein; Short=Eps15R) HSP 1 Score: 94.7449 bits (234), Expect = 1.159e-18 Identity = 82/335 (24.48%), Postives = 164/335 (48.96%), Query Frame = 0
Query: 44 WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDL-ATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVSPSTFEDKRRENFNKGQAELEKRRQSIVDQQKREADERKKKEAAEAVEKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGV----ADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTN-----GEQITEFEFRRNEKKKKVEQTQKLLE 368
W + + ++ IF + D G++ G + + + +GL QN+LA IW L+D GKLS D+F ++ Y +KG P L D++PPS R P P ++GS GS V K ++ ++ A+L++ + S+ E D R+K+EA +K + QEL Q ++ E + +EL + +Q+ Q++L ++ ++ ++D + R + + T+ I++ +T + +D+KS D + ++ E +N++ + QL+ + + Q+E+ +L S + ++++ R E + +EQ ++L+
Sbjct: 269 WVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGP-----DSSGSL----GSGEFTGV--------KELDDISQEIAQLQREKYSL------EQDIREKEEAIR--QKTSEVQEL--QNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSE-LNRLQQEETQLEQ------SIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLD 569 HSP 2 Score: 72.0182 bits (175), Expect = 1.297e-11 Identity = 53/163 (32.52%), Postives = 77/163 (47.24%), Query Frame = 0
Query: 20 PVPVVLPVSSAASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRP---FPAPGPQIVSTA---GSTVSTPGSSRAESVVSPSTFEDKR 176
P P SS V P + A W + ++K+ IF + G L G + + L+ + LP +VL ++W LSDID +G L DEF V+ +L A + EP+P LP +IPPS R FP P + ++ S STP S+ S + K
Sbjct: 99 PPPKFHDTSSPLMVTPPSAEA--HWAVRVEEKAKFDGIFESLLPIN-GLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKH 258
BLAST of intersectin-1 isoform x2 vs. SwissProt
Match: gi|341941109|sp|Q60902.3|EP15R_MOUSE (RecName: Full=Epidermal growth factor receptor substrate 15-like 1; AltName: Full=Epidermal growth factor receptor pathway substrate 15-related sequence; Short=Eps15-rs; AltName: Full=Eps15-related protein; Short=Eps15R) HSP 1 Score: 91.2781 bits (225), Expect = 1.597e-17 Identity = 72/276 (26.09%), Postives = 138/276 (50.00%), Query Frame = 0
Query: 43 AWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDL-ATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVSPSTFEDKRRENFNKGQAELEKRRQSIVDQQKREADERKKKEAAEAVEKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGV----ADVKSFIDTMRSSRDEKMNKMNALKQQL 313
AW + + ++ IF + D G++ G + + + +GL QN+LA IW L+D GKLS ++F ++ Y +KG P L D++PPS R P P + ST S V K ++ ++ A+L++ + S+ E D R+K+EA +K + QEL Q ++ E + +EL + +Q+ Q++L ++ ++ ++D + R + + T+ I++ +T + +D+KS D + ++ E +N++ + QL
Sbjct: 266 AWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKEQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPIP---------DSSSTLASGEFTGV--------KELDDISQEIAQLQREKYSL------EQDIREKEEAIR--QKTSEVQEL--QNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQTISSLKTQIQSQESDLKSQEDDLNRAKSE-LNRLQQEETQL 513
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|328721590|ref|XP_003247350.1| (PREDICTED: intersectin-1 isoform X2 [Acyrthosiphon pisum]) HSP 1 Score: 516.538 bits (1329), Expect = 4.878e-160 Identity = 343/955 (35.92%), Postives = 504/955 (52.77%), Query Frame = 0
Query: 12 VTPALSHAPVPVVLPVSSA---ASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAES---VVSPSTFEDKRRENFNKGQAELEKRRQSIVD--------------------------QQKREADE-----RKKKEAAEAV---------EKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTD-PDHAWGNEEP------EPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFV-TYDPS-----------------------ALEAIA-------AEEVETD------------------IVAKVIVDWTGEDS--FSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVV---PEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESN-----APRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL------------EAKEGVGPA--------KDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
+ PAL AP PV+S S+ +PG+ W + T+ KY+ IF D++R GFL G+QAR ++ T LPQNVLAQIW LSD+D +G+L CDEF+++ YLCDLA GE + LP ++IPPS R ++++ P ES +++ +TFEDKR+ENF KGQAELE+RR+++++ Q+KR DE RK+KE + ++E R+E+ERQR +EWE R EL RQ EQE +L+LK K ++ D+ + D+++ ++++I+ R V VKS ID+MR++RD +MN+M+ LK LK+QN+RL+ V+QEK ++E+K S E + + + KK + Q ++++ + E K + E S+D K L +++E C+ +Y S++E +++ K + +E++ D AW N P E + +SS + ALY+FE N DEL+F+ GD I+V + EPGWL GE GWFPE++V T D S LE IA + ETD I A+V+ DWTG+DS S+V G +II + ++W +GK D G+FP +SV E + +P+D E ++ PY+S EPGDL + + + V K+ +WWTG D+ G+FPSNYV P+ + N P S V++ V S P P + N P + K+ K K E+A V+APY ATSTEQLSL RGQ++ IRKK +GWW+GE+Q KG+KRQIGWFPASYVK L + V P L V ALF + +DEL+F++ +II L+SK++ WWRG+L ++G+FP NYV
Sbjct: 186 IKPALPAAPSLPGTPVASMPMPISIDSPGNQE---WAVPHQTKLKYTQIFNTTDRTRTGFLTGVQARGIMVATQLPQNVLAQIWNLSDMDKDGQLCCDEFVLAMYLCDLAKSGEKIRIPLPPELIPPSVR----------RQRQNSLTAPSEGTPESDSCLINQTTFEDKRKENFEKGQAELERRRKALLEIQRKEQEERERKEREEQERREKIRLEQEKRRQDELEIQMRKQKELEQEREEQRKRAQEQREAARKEMERQRQLEWEKQRSMELQQQRQKEQETVLKLKGKNQSLTIDLQQMTDKVRELSQKISETRASVTGVKSTIDSMRTTRDTQMNEMSRLKSTLKEQNQRLITVSQEKIRLEAKNKMNPSIETAEIQEQTQSAVSNKKLTFKSLQDKIDDLNSQIELKKQDVENNNSSIDQLKTQLTKLVEDCEKIYPSYEENTKKVMEMKKSKAKEMSSWGDDAW-NSAPTTDWVEEKSATTLESSAYKKCRALYEFEARNTDELSFQPGDIIMVPLEQNAEPGWLTGELKNMTGWFPESYVETVDGSDDIRDIIANRQAPLEDNFVSTQKPLEGIAELPENELGQGFETDDFSISNPKLILGHGKSVNIKAQVLNDWTGKDSTCLSLVAG-DIIDVTENQDDWWYGKTSDNRF-GWFPKSSVSV----IENTIKDTNIPSDK--QEYYIVLYPYESVEPGDLNMNQDEVVLVTKKDGDWWTGIIGDRSGIFPSNYVQYLDPQPKETTVNKNPPFETASSVKSETSVTSSPLTTPIMLEPQKPNGSRSVTPDLASTKITKGTKKAEVATVIAPYTATSTEQLSLQRGQLVKIRKKTTTGWWEGELQ-AKGQKRQIGWFPASYVKPLGNTGRANSPATKSNQSAVMPVTTPTPSSNNSLEKVIALFPFNAVHNDELTFQKDEIITLVSKDEQAWWRGELNGKTGLFPSNYV 1117 HSP 2 Score: 79.337 bits (194), Expect = 2.670e-11 Identity = 69/244 (28.28%), Postives = 116/244 (47.54%), Query Frame = 0
Query: 607 YQSTEPGDLVFEEGQKIRV-LVKNSE--WWTGQYDDKLGVFPSNYVVPEGEAGA-------PNAEAPPPGESQVEASAPVE--SEDAANPPPANPDESNAPRIKPKKVKKDDKTMEL-AKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLE--AKEGVGPAKDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
+++ +L F+ G I V L +N+E W TG+ + G FP +YV E G+ N +AP ++ V P+E +E N + + PK + K++ + A+V+ + + LSL G +I + + D W+ GK + GWFP S V ++E K+ P+ L+ YE +L+ Q +++ L++K+DGDWW G + SG+FP NYV+
Sbjct: 673 FEARNTDELSFQPGDIIMVPLEQNAEPGWLTGELKNMTGWFPESYV--ETVDGSDDIRDIIANRQAPLE-DNFVSTQKPLEGIAELPENELGQGFETDDFSISNPKLILGHGKSVNIKAQVLNDWTGKDSTCLSLVAGDIIDVTENQDDWWY------GKTSDNRFGWFPKSSVSVIENTIKDTNIPSDKQEYYIVLYPYESVEPGDLNMNQDEVV-LVTKKDGDWWTGIIGDRSGIFPSNYVQ 906
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|668454552|gb|KFB42982.1| (AGAP009037-PA-like protein [Anopheles sinensis]) HSP 1 Score: 501.516 bits (1290), Expect = 8.792e-158 Identity = 325/941 (34.54%), Postives = 487/941 (51.75%), Query Frame = 0
Query: 30 AASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESV-------VSPSTFEDKRRENFNKGQAELEKRRQSIVD---------------------QQKREADERKKKEA-------------------AEAVEKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELT----DPDHAWGNE------------EPEPV-SAGGDSSDAVEAY----ALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGEDSFSMVKGA-EIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPP----PGESQVEASAP---------------------------------VESEDAANPPPANPDES-------NAPRIKPKKVKKDDKTM-----------ELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVG---PAKD---------LGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
A S+ +PG W I + KY+ +F D++R GFL G QARN ++QT LPQ +LAQIW L+D+D +G+L C+EF+++ YLCD+A GE +P LP D++PPSFR + +VS+ +VS+ G+ V + ++FEDKR+ENF+KGQAELE+RR++++D + K EA+ +K++E E +KE R+E+E+QR EWE + E+ HRQ EQE +L+LKA+ ++ ++ +RIK ++++I + R GV +VK+ ID MRS+RD +M++M LK Q+K+QN RL++++QEKA++++K + GE TE + + K+ ++Q + LE K++ E + RE L K L +I++C+ LY +D +R +I K+ R E D +W E EP V S G++ Y A+Y+F N DE++F+ GD ++V + EPGWL GE NG GWFPET+V E+V+T++ ++V+ A E I P E++ T + + N E N D E +VA YQS E GDLVF+ G+ I V K +WWTG ++ G+FPSNYV + EA A N P +Q+E S P ++EDA N + + S AP + ++ +M E+A+V+APYEATS+EQLSL RGQ+I+IRKK DSGWW+GE+Q KG++RQIGWFPA+YVK+L+ G P L V AL+ Y+ DELSF++ DII +L +++ +WWRG+L +G+FP NYV
Sbjct: 295 APSIESPGQVE---WAIKGPAKLKYTQLFNTTDRNRSGFLTGPQARNIMVQTKLPQALLAQIWALADMDADGRLGCEEFVLAMYLCDMAAAGEKVPTTLPPDLVPPSFRKTTSRHGSVVSSRHGSVSSQGAPVHAPVELDPLSGLPQTSFEDKRKENFDKGQAELERRRKALMDIQKKEQEERERKEREEQEKIRKAKLEAELKKQQELEKELQRQRELEQEREEQRKRELEKKELARKEMEKQRQQEWEAQKIAEMQQHRQREQENVLKLKAQNQSLSVELSTFNERIKELSQKICDTRVGVTNVKTTIDGMRSTRDTQMSEMAQLKAQVKEQNHRLVQLSQEKAKLDAKNKS------GE--TESQLQFTNKQIVIQQLKDKLENTKQQIENKTTDISLNREQLTELKSQLTNLIDSCEKLYGEYDLQRIQILEMKNNRKNESYSSAWDTGSSWPTETATVAHTTAVTSEPAAVTSLAGENLQTPPGYVKYRAIYEFSARNGDEISFQPGDIVMVPLEQNAEPGWLAGEINGHTGWFPETYV------------EKVDTNL--------------NVVEAAPETIAYTEPVEDYS------TAISAPAATEYAATNNAEATCNGD----------VEYYVACYAYQSAEVGDLVFDAGETIAVSKKEGDWWTGTIGNRTGIFPSNYVQKQ-EAEAMNGNQTSYDEQPMSAQIEQSQPPAQTYEQETKRKQSTPAATTTTTNTTTTTPSNTQDAEDARNQAELDSEVSQINTQPPQAPAVNEDNIRYSSMSMTSATPSLRRKGEVAQVIAPYEATSSEQLSLQRGQLIMIRKKTDSGWWEGELQ-AKGRRRQIGWFPATYVKILQGGRNSGRNTPVSASKVELTETILDKVIALYPYKALNDDELSFEKDDIIAVLGRDEPEWWRGELNGTTGLFPSNYV 1180
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|328721586|ref|XP_001947769.2| (PREDICTED: intersectin-1 isoform X1 [Acyrthosiphon pisum] >gi|328721588|ref|XP_003247349.1| PREDICTED: intersectin-1 isoform X1 [Acyrthosiphon pisum]) HSP 1 Score: 509.99 bits (1312), Expect = 1.797e-157 Identity = 344/969 (35.50%), Postives = 505/969 (52.12%), Query Frame = 0
Query: 12 VTPALSHAPVPVVLPVSSA---ASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAES---VVSPSTFEDKRRENFNKGQAELEKRRQSIVD--------------------------QQKREADE-----RKKKEAAEAV---------EKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTD-PDHAWGNEEP------EPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFV-TYDPS-----------------------ALEAIA-------AEEVETD------------------IVAKVIVDWTGEDS--FSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVV---PEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPR-IKP------------------KKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL------------EAKEGVGPA--------KDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
+ PAL AP PV+S S+ +PG+ W + T+ KY+ IF D++R GFL G+QAR ++ T LPQNVLAQIW LSD+D +G+L CDEF+++ YLCDLA GE + LP ++IPPS R ++++ P ES +++ +TFEDKR+ENF KGQAELE+RR+++++ Q+KR DE RK+KE + ++E R+E+ERQR +EWE R EL RQ EQE +L+LK K ++ D+ + D+++ ++++I+ R V VKS ID+MR++RD +MN+M+ LK LK+QN+RL+ V+QEK ++E+K S E + + + KK + Q ++++ + E K + E S+D K L +++E C+ +Y S++E +++ K + +E++ D AW N P E + +SS + ALY+FE N DEL+F+ GD I+V + EPGWL GE GWFPE++V T D S LE IA + ETD I A+V+ DWTG+DS S+V G +II + ++W +GK D G+FP +SV E + +P+D E ++ PY+S EPGDL + + + V K+ +WWTG D+ G+FPSNYV P+ + N P S V++ V S P P + N R + P K+ K K E+A V+APY ATSTEQLSL RGQ++ IRKK +GWW+GE+Q KG+KRQIGWFPASYVK L + V P L V ALF + +DEL+F++ +II L+SK++ WWRG+L ++G+FP NYV
Sbjct: 186 IKPALPAAPSLPGTPVASMPMPISIDSPGNQE---WAVPHQTKLKYTQIFNTTDRTRTGFLTGVQARGIMVATQLPQNVLAQIWNLSDMDKDGQLCCDEFVLAMYLCDLAKSGEKIRIPLPPELIPPSVR----------RQRQNSLTAPSEGTPESDSCLINQTTFEDKRKENFEKGQAELERRRKALLEIQRKEQEERERKEREEQERREKIRLEQEKRRQDELEIQMRKQKELEQEREEQRKRAQEQREAARKEMERQRQLEWEKQRSMELQQQRQKEQETVLKLKGKNQSLTIDLQQMTDKVRELSQKISETRASVTGVKSTIDSMRTTRDTQMNEMSRLKSTLKEQNQRLITVSQEKIRLEAKNKMNPSIETAEIQEQTQSAVSNKKLTFKSLQDKIDDLNSQIELKKQDVENNNSSIDQLKTQLTKLVEDCEKIYPSYEENTKKVMEMKKSKAKEMSSWGDDAW-NSAPTTDWVEEKSATTLESSAYKKCRALYEFEARNTDELSFQPGDIIMVPLEQNAEPGWLTGELKNMTGWFPESYVETVDGSDDIRDIIANRQAPLEDNFVSTQKPLEGIAELPENELGQGFETDDFSISNPKLILGHGKSVNIKAQVLNDWTGKDSTCLSLVAG-DIIDVTENQDDWWYGKTSDNRF-GWFPKSSVSVI----ENTIKDTNIPSDK--QEYYIVLYPYESVEPGDLNMNQDEVVLVTKKDGDWWTGIIGDRSGIFPSNYVQYLDPQPKETTVNKNPPFETASSVKSETSVTSSPLTTPIMLEPQKPNGSRSVTPDLASTKRESSATEDSENDDKITKGTKKAEVATVIAPYTATSTEQLSLQRGQLVKIRKKTTTGWWEGELQ-AKGQKRQIGWFPASYVKPLGNTGRANSPATKSNQSAVMPVTTPTPSSNNSLEKVIALFPFNAVHNDELTFQKDEIITLVSKDEQAWWRGELNGKTGLFPSNYV 1131 HSP 2 Score: 79.337 bits (194), Expect = 2.609e-11 Identity = 69/244 (28.28%), Postives = 116/244 (47.54%), Query Frame = 0
Query: 607 YQSTEPGDLVFEEGQKIRV-LVKNSE--WWTGQYDDKLGVFPSNYVVPEGEAGA-------PNAEAPPPGESQVEASAPVE--SEDAANPPPANPDESNAPRIKPKKVKKDDKTMEL-AKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLE--AKEGVGPAKDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
+++ +L F+ G I V L +N+E W TG+ + G FP +YV E G+ N +AP ++ V P+E +E N + + PK + K++ + A+V+ + + LSL G +I + + D W+ GK + GWFP S V ++E K+ P+ L+ YE +L+ Q +++ L++K+DGDWW G + SG+FP NYV+
Sbjct: 673 FEARNTDELSFQPGDIIMVPLEQNAEPGWLTGELKNMTGWFPESYV--ETVDGSDDIRDIIANRQAPLE-DNFVSTQKPLEGIAELPENELGQGFETDDFSISNPKLILGHGKSVNIKAQVLNDWTGKDSTCLSLVAGDIIDVTENQDDWWY------GKTSDNRFGWFPKSSVSVIENTIKDTNIPSDKQEYYIVLYPYESVEPGDLNMNQDEVV-LVTKKDGDWWTGIIGDRSGIFPSNYVQ 906
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|1000213430|gb|KXJ82859.1| (hypothetical protein RP20_CCG010891 [Aedes albopictus]) HSP 1 Score: 496.123 bits (1276), Expect = 1.725e-156 Identity = 315/896 (35.16%), Postives = 477/896 (53.24%), Query Frame = 0
Query: 44 WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVSP--------STFEDKRRENFNKGQAELEKRRQSIVD---------------------QQKREADERKKKEA-------------------AEAVEKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTDPDHAWGNEEPEPVSAGGDSSDA------------------VEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKV---IVDWTGEDSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYV-----------------VPEGEAG-APNAEAPPPGESQVEASAPVESEDAANPPPA------NPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVG---PAKD---------LGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
W I + KY+ +F D++R G L G QARN ++QT LPQ LAQIW L+D+D +G+L C+EF+++ YLCDLA +GE +P LP ++IPPSFR + +VS+ +VS+ G+ +VV S+FEDKR+ENF+KGQAEL++RR++++D + K EA+ +K++E E +KE R+ELE+QR +EWE + E+ RQ EQE +L+LKA+ ++ ++ ++IK ++++I + R GV +VKS ID MR++RD +M++M LK ++KDQN+RL++++QEKA++++K GE TE + + + K+ ++Q + LE K++ E + + + L K L +I++C+ LY +D +R +I K+ R E AW PV D+S A V+ A+Y+F N DE+ F+ GD ++V + EPGWL GE +G GWFPET+V S L + A E + +A + +T + V+G + ++ TE + + ++ DE T + E +VA YQS E GDLVF+ G+ + V K +WWTG ++ G+FPSNYV E E + + +Q EA + V S+ PPPA N S+ P KK E+A+V+APYEATS+EQLSLTRGQ+I+IRKK DSGWW+GE+Q KG++RQIGWFPA+YVK+L+ G P L V AL+ Y+ DELSF++ DII +L +++ +WWRG+L +G+FP NYV
Sbjct: 256 WAIKGPAKLKYTQLFNTTDRNRSGHLTGPQARNIMVQTKLPQATLAQIWALADMDSDGRLGCEEFVLAMYLCDLALQGEKIPTTLPPEMIPPSFRKTTSRHGSVVSSRHGSVSSQGAPVHPAVVDADPMSGLPQSSFEDKRKENFDKGQAELDRRRKALMDIQKKEQEERERKEREEQEKIRKAKMEAELKKQQELEKELQRQRELEQEREEQRKRELEKKELARKELEKQRQLEWETQKISEMQLQRQREQENVLKLKAQNQSLSVELSTFNEKIKELSQKICDTRVGVTNVKSTIDGMRTTRDTQMSEMAQLKAKVKDQNQRLVQLSQEKAKLDAKNK------TGE--TESQLQFSNKQIIIQQLKDKLENTKQQIENKTTDIDINSKQLTELKSQLTDLIDSCEKLYMEYDMQRIQILEMKNNRKNE--SYTSAWDTANSWPVH---DTSAAAVVETVVPSEDIKTPPGYVKYRAIYEFSARNADEITFQPGDIVMVPLEQNAEPGWLAGEIHGHTGWFPETYVEKVDSNLNTVVAAP-EPEAIAYTEPEAITYTATTESNEVQGTSLEAT----------RIASTEDNTSYNNNVV-----------DEQFAATYNGDVEYYVACYAYQSAEAGDLVFDAGEIVAVTKKEGDWWTGNIGNRTGIFPSNYVQKQETEIINGNQQQQITQQESETNRKQSTQDAEDARNQAEADSEV-SQINTQPPPAPAANEENIRYSSMSSATPSLRKKG----EVAQVIAPYEATSSEQLSLTRGQLIMIRKKTDSGWWEGELQ-AKGRRRQIGWFPATYVKILQGGRNSGRNTPVSASKVELTETILDKVIALYPYKALNDDELSFEKDDIISVLGRDEPEWWRGELNGTTGLFPSNYV 1110
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|1218238973|ref|XP_021700601.1| (intersectin-1 isoform X3 [Aedes aegypti]) HSP 1 Score: 498.049 bits (1281), Expect = 1.757e-156 Identity = 320/898 (35.63%), Postives = 477/898 (53.12%), Query Frame = 0
Query: 44 WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVSP--------STFEDKRRENFNKGQAELEKRRQSIVDQQKR---------------------EADERKKKEA-------------------AEAVEKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTDPDHAWGNEEPEPVSAGGDSSDA------------------VEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGEDSFSMVKGAEII-VIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYV----------------------VPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPA------NPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVG---PAKD---------LGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
W I + KY+ +F D++R G L G QARN ++QT LPQ LAQIW L+D+D +G+L C+EF+++ YLCDLA +GE +P LP ++IPPSFR + +V + +VS+ G+ ++V S+FEDKR+ENF+KGQAEL++RR++++D QK+ EA+ +K++E E +KE R+ELE+QR +EWE + E+ RQ EQE +L+LKA+ ++ ++ ++IK ++++I + R GV +VKS ID MR++RD +M++M LK ++KDQN+RL++++QEKA++++K GE TE + + + K+ ++Q + LE K++ E + + + L K L +I++C+ LY +D +R +I K+ R E AW PV D+S A V+ A+Y+F N DE+ F+ GD ++V + EPGWL GE +G GWFPET+V S L + A E E + +T + + AE V G EE ++ TE N DE T + E +VA YQS E GDLVF+ G+ + V K+ +WWTG ++ G+FPSNYV V ++ EA +Q EA + V S+ PPPA N S+ P KK E+A+V+APYEATS+EQLSLTRGQ+I+IRKK DSGWW+GE+Q KG++RQIGWFPA+YVK+L+ G P L V AL+ Y+ DELSF++ DII +L +++ +WWRG+L +G+FP NYV
Sbjct: 325 WAIKGPAKLKYTQLFNTTDRNRSGHLTGPQARNIMVQTKLPQATLAQIWALADMDSDGRLGCEEFVLAMYLCDLALQGEKIPTTLPPEMIPPSFRKTTSRHGSVVGSRHGSVSSQGAPVHPAIVDADPLSGLPQSSFEDKRKENFDKGQAELDRRRKALMDIQKKEQEERDRKEREEQEKIRKAKMEAELKKQQELEKELQRQRELEQEREEQRKRELEKKELARKELEKQRQLEWETQKISEMQLQRQREQENVLKLKAQNQSLSVELSTFNEKIKELSQKICDTRVGVTNVKSTIDGMRTTRDTQMSEMAQLKAKVKDQNQRLVQLSQEKAKLDAKNK------TGE--TESQLQFSNKQIIIQQLKDKLENTKQQIENKTTDIDINSKQLTELKSQLTDLIDSCEKLYMEYDMQRIQILEMKNNRKNE--SYTSAWDTANSWPVH---DTSAAAVVETVVPSEDIKTPPGYVKYRAIYEFSARNADEITFQPGDIVMVPLEQNAEPGWLAGEIHGHTGWFPETYVEKVDSNLNTVVAPEPEA-------IAYTEPAAITYTAPAESNEVQGTSLEE---TRIASTEN-----------NTSHNNNVVDEQFTATYNGDVEYYVACYAYQSAEIGDLVFDAGEIVAVTKKDGDWWTGNIGNRTGIFPSNYVQKQETEIINGNQQQQITQQETEVNRKQSTQDAEEA----RNQAEADSEV-SQINTQPPPAPAANEENIRYSSMSSATPSLRKKG----EVAQVIAPYEATSSEQLSLTRGQLIMIRKKTDSGWWEGELQ-AKGRRRQIGWFPATYVKILQGGRNSGRNTPVSASKVELTETILDKVIALYPYKALNDDELSFEKDDIISVLGRDEPEWWRGELNGTTGLFPSNYV 1178
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|985398232|ref|XP_015366681.1| (PREDICTED: intersectin-1 isoform X2 [Diuraphis noxia]) HSP 1 Score: 506.523 bits (1303), Expect = 2.875e-156 Identity = 339/958 (35.39%), Postives = 501/958 (52.30%), Query Frame = 0
Query: 6 SSPVNTVTPALSHAPVPVVLPVSSAASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAES---VVSPSTFEDKRRENFNKGQAELEKRRQSIVD--------------------------QQKREADE-----RKKKEAAEAV---------EKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTD-PDHAWGNEEP------EPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFV-TYDPS-----------------------ALEAI-------AAEEVETD------------------IVAKVIVDWTGEDS--FSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVV---PEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDE-----SNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL------------EAKEGVGPA--------KDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
+ PV + PA P V + S+ +PG+ W + T+ KY+ IF D++R GFL G+QAR ++ T LPQNVLAQIW LSD+D +G+L CDEF+++ YLCDLA GE + LP ++IPPS R ++++ P ES +V+ +TFEDKR+ENF KGQAELE+RR+++++ Q+KR DE RK+KE + ++E R+E+ERQR +EWE R EL RQ EQE +L+LK K ++ D+ + D+++ ++++I+ R V VKS ID+MR++RD +MN+M+ LK LK+QN+RL+ V+QEK ++E+K +S E + + + KK + Q ++++ + E K + E S+D K L +++E C+ +Y S++E +++ K + +E++ D AW N P E ++ +SS + ALY+FE N DEL+F+ GD I+V + EPGWL GE K GWFPE++V T D S LE I + E D I AKV+ DWTG+DS S+V G +II + ++W +G+ D F S SV+ E V +P+D E ++ PY+S EPGDL + + + V K+ +WWTG D+ G+FPSNYV P+ + N P S V++ V S P + S P + K+ K K E+A V+APY ATSTEQLSL RGQ++ IRKK +GWW+GE+Q KG+KRQIGWFPASYVK L + + P L V ALF + +DEL+F++ +II L+SK++ WWRG+L ++G+FP NYV
Sbjct: 183 TEPVKSALPAAPSLPGTPVASMPMPISIDSPGNQE---WAVPHQTKLKYTQIFNTTDRTRTGFLTGVQARGIMVATQLPQNVLAQIWNLSDMDKDGQLXCDEFVLAMYLCDLAKSGEKIRIPLPPELIPPSVR----------RQRQNSLTAPSEGTPESDSCLVNQTTFEDKRKENFEKGQAELERRRKALLEIQRKEQEERERKEREEQDRREKIRLEQEKRRQDELEIQMRKQKELEQEREEQRKRAQEQREAARKEMERQRQLEWEKQRSMELQQQRQKEQETVLKLKGKNQSLTIDLQQMTDKVRELSQKISETRASVTGVKSTIDSMRTTRDTQMNEMSRLKSTLKEQNQRLITVSQEKIRLEAKNKMKSSIETAEIQEQTQSAISNKKLAFKSLQDKIDDLNSQIELKKQDVENNNSSIDQLKTQLTKLVEDCEKVYPSYEENIKKVIEMKKNKAKEMSSWGDDAW-NSAPTTDWVEEKSASNLESSAYKKCRALYEFEARNTDELSFQPGDIIMVPLEQNAEPGWLTGELKNKTGWFPESYVETVDGSDDIRDIIANRQAPLEDNFASTQKPLEGIDELPENELGQGFENDEFSNSYPKLILGRGKPVNIKAKVLNDWTGKDSTYLSLVAG-DIIDVTENQDDWWYGRTSDNRVGWFQKS---SVSIIENAVKD----IPSDK--QEYYIVLYPYESVEPGDLNMNQDEVVLVTKKDGDWWTGIIGDRSGIFPSNYVQYLDPQPKETTVNKNPPFETASSVKSETSVTSSPLTTPIMLESQKLGGSRSVTPDLTSTKITKGTKKAEVATVIAPYTATSTEQLSLQRGQLVKIRKKTTTGWWEGELQ-AKGQKRQIGWFPASYVKPLGNTGRANSPATKSNQSAIMPVTTTTPSSNNTLEKVIALFPFNAVHNDELTFQKDEIITLVSKDEQAWWRGELNGKTGLFPSNYV 1115 HSP 2 Score: 79.7221 bits (195), Expect = 2.086e-11 Identity = 68/249 (27.31%), Postives = 113/249 (45.38%), Query Frame = 0
Query: 607 YQSTEPGDLVFEEGQKIRV-LVKNSE--WWTGQYDDKLGVFPSNYVVPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPA----------------NPDESNAPRIKPKKVKKDDKTMEL-AKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVGPAKDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
+++ +L F+ G I V L +N+E W TG+ +K G FP +YV E G+ + + AP+E A+ P N + SN+ PK + K + + AKV+ + + LSL G +I + + D W+ G+ ++GWF S V ++E P+ L+ YE +L+ Q +++ L++K+DGDWW G + SG+FP NYV+
Sbjct: 673 FEARNTDELSFQPGDIIMVPLEQNAEPGWLTGELKNKTGWFPESYV--ETVDGSDDIR-----DIIANRQAPLEDNFASTQKPLEGIDELPENELGQGFENDEFSNS---YPKLILGRGKPVNIKAKVLNDWTGKDSTYLSLVAGDIIDVTENQDDWWY------GRTSDNRVGWFQKSSVSIIENAVKDIPSDKQEYYIVLYPYESVEPGDLNMNQDEVV-LVTKKDGDWWTGIIGDRSGIFPSNYVQ 904
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|1121167741|ref|XP_019529463.1| (PREDICTED: intersectin-1 isoform X3 [Aedes albopictus]) HSP 1 Score: 495.352 bits (1274), Expect = 1.410e-155 Identity = 314/895 (35.08%), Postives = 475/895 (53.07%), Query Frame = 0
Query: 44 WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVSP--------STFEDKRRENFNKGQAELEKRRQSIVD---------------------QQKREADERKKKEA-------------------AEAVEKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTDPDHAWGNEEPEPVSAGGDSSDA------------------VEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKV---IVDWTGEDSFSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVV---PEGEAGAPNAEAPPPGESQVEASAPVESEDAAN--------------PPPA------NPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVG---PAKD---------LGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
W I + KY+ +F D++R G L G QARN ++QT LPQ LAQIW L+D+D +G+L C+EF+++ YLCDLA +GE +P LP ++IPPSFR + +VS+ +VS+ G+ +VV S+FEDKR+ENF+KGQAEL++RR++++D + K EA+ +K++E E +KE R+ELE+QR +EWE + E+ RQ EQE +L+LKA+ ++ ++ ++IK ++++I + R GV +VKS ID MR++RD +M++M LK ++KDQN+RL++++QEKA++++K GE TE + + + K+ ++Q + LE K++ E + + + L K L +I++C+ LY +D +R +I K+ R E AW PV D+S A V+ A+Y+F N DE+ F+ GD ++V + EPGWL GE +G GWFPET+V S L + A E + +A + +T + V+G + ++ TE + + ++ DE T + E +VA YQS E GDLVF+ G+ + V K +WWTG ++ G+FPSNYV E G + + ++EDA N PPPA N S+ P KK E+A+V+APYEATS+EQLSLTRGQ+I+IRKK DSGWW+GE+Q KG++RQIGWFPA+YVK+L+ G P L V AL+ Y+ DELSF++ DII +L +++ +WWRG+L +G+FP NYV
Sbjct: 320 WAIKGPAKLKYTQLFNTTDRNRSGHLTGPQARNIMVQTKLPQATLAQIWALADMDSDGRLGCEEFVLAMYLCDLALQGEKIPTTLPPEMIPPSFRKTTSRHGSVVSSRHGSVSSQGAPVHPAVVDADPMSGLPQSSFEDKRKENFDKGQAELDRRRKALMDIQKKEQEERERKEREEQEKIRKAKMEAELKKQQELEKELQRQRELEQEREEQRKRELEKKELARKELEKQRQLEWETQKISEMQLQRQREQENVLKLKAQNQSLSVELSTFNEKIKELSQKICDTRVGVTNVKSTIDGMRTTRDTQMSEMAQLKAKVKDQNQRLVQLSQEKAKLDAKNK------TGE--TESQLQFSNKQIIIQQLKDKLENTKQQIENKTTDIDINSKQLTELKSQLTDLIDSCEKLYMEYDMQRIQILEMKNNRKNE--SYTSAWDTANSWPVH---DTSAAAVVETVVPSEDIKTPPGYVKYRAIYEFSARNADEITFQPGDIVMVPLEQNAEPGWLAGEIHGHTGWFPETYVEKVDSNLNTVVAAP-EPEAIAYTEPEAITYTATTDSNEVQGTSLEAT----------RIASTEDNTSYNNNVV-----------DEQFAATYNGDVEYYVACYAYQSAEAGDLVFDAGEIVAVTKKEGDWWTGNIGNRTGIFPSNYVQKQETENINGNQQQQITQQETETNRKQSTQDAEDARNQAEADSEVSQINTQPPPAPAANEENIRYSSMSSATPSLRKKG----EVAQVIAPYEATSSEQLSLTRGQLIMIRKKTDSGWWEGELQ-AKGRRRQIGWFPATYVKILQGGRNSGRNTPVSASKVELTETILDKVIALYPYKALNDDELSFEKDDIISVLGRDEPEWWRGELNGTTGLFPSNYV 1174
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|1218238970|ref|XP_021700600.1| (intersectin-1 isoform X2 [Aedes aegypti]) HSP 1 Score: 494.582 bits (1272), Expect = 3.677e-155 Identity = 324/913 (35.49%), Postives = 481/913 (52.68%), Query Frame = 0
Query: 44 WNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVSP--------STFEDKRRENFNKGQAELEKRRQSIVDQQKR---------------------EADERKKKEA-------------------AEAVEKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTDPDHAWGNEEPEPVSAGGDSSDA------------------VEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFVTYDPSALEAIAAEEVETDIVAKVIVDWTGEDSFSMVKGAEII-VIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYV-----VPEG-EAGA-PNAEAPPPGE------------------------------SQVEASAPVESEDAANPPPA------NPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLEAKEGVG---PAKD---------LGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
W I + KY+ +F D++R G L G QARN ++QT LPQ LAQIW L+D+D +G+L C+EF+++ YLCDLA +GE +P LP ++IPPSFR + +V + +VS+ G+ ++V S+FEDKR+ENF+KGQAEL++RR++++D QK+ EA+ +K++E E +KE R+ELE+QR +EWE + E+ RQ EQE +L+LKA+ ++ ++ ++IK ++++I + R GV +VKS ID MR++RD +M++M LK ++KDQN+RL++++QEKA++++K GE TE + + + K+ ++Q + LE K++ E + + + L K L +I++C+ LY +D +R +I K+ R E AW PV D+S A V+ A+Y+F N DE+ F+ GD ++V + EPGWL GE +G GWFPET+V S L + A E E + +T + + AE V G EE ++ TE N DE T + E +VA YQS E GDLVF+ G+ + V K+ +WWTG ++ G+FPSNYV V G E G+ P+ P E +Q EA + V S+ PPPA N S+ P KK E+A+V+APYEATS+EQLSLTRGQ+I+IRKK DSGWW+GE+Q KG++RQIGWFPA+YVK+L+ G P L V AL+ Y+ DELSF++ DII +L +++ +WWRG+L +G+FP NYV
Sbjct: 325 WAIKGPAKLKYTQLFNTTDRNRSGHLTGPQARNIMVQTKLPQATLAQIWALADMDSDGRLGCEEFVLAMYLCDLALQGEKIPTTLPPEMIPPSFRKTTSRHGSVVGSRHGSVSSQGAPVHPAIVDADPLSGLPQSSFEDKRKENFDKGQAELDRRRKALMDIQKKEQEERDRKEREEQEKIRKAKMEAELKKQQELEKELQRQRELEQEREEQRKRELEKKELARKELEKQRQLEWETQKISEMQLQRQREQENVLKLKAQNQSLSVELSTFNEKIKELSQKICDTRVGVTNVKSTIDGMRTTRDTQMSEMAQLKAKVKDQNQRLVQLSQEKAKLDAKNK------TGE--TESQLQFSNKQIIIQQLKDKLENTKQQIENKTTDIDINSKQLTELKSQLTDLIDSCEKLYMEYDMQRIQILEMKNNRKNE--SYTSAWDTANSWPVH---DTSAAAVVETVVPSEDIKTPPGYVKYRAIYEFSARNADEITFQPGDIVMVPLEQNAEPGWLAGEIHGHTGWFPETYVEKVDSNLNTVVAPEPEA-------IAYTEPAAITYTAPAESNEVQGTSLEE---TRIASTEN-----------NTSHNNNVVDEQFTATYNGDVEYYVACYAYQSAEIGDLVFDAGEIVAVTKKDGDWWTGNIGNRTGIFPSNYVQKQETVSTGLETGSEPSVVEPEKQEIINGNQQQQITQQETEVNRKQSTQDAEEARNQAEADSEV-SQINTQPPPAPAANEENIRYSSMSSATPSLRKKG----EVAQVIAPYEATSSEQLSLTRGQLIMIRKKTDSGWWEGELQ-AKGRRRQIGWFPATYVKILQGGRNSGRNTPVSASKVELTETILDKVIALYPYKALNDDELSFEKDDIISVLGRDEPEWWRGELNGTTGLFPSNYV 1197
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|1101370675|ref|XP_018916717.1| (PREDICTED: intersectin-1 isoform X2 [Bemisia tabaci]) HSP 1 Score: 504.982 bits (1299), Expect = 5.535e-155 Identity = 332/962 (34.51%), Postives = 500/962 (51.98%), Query Frame = 0
Query: 2 ASAYSSPVNTVTPALSHAP-VPVVLPVSSAASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAESVVSPSTFEDKRRENFNKGQAELEKRRQSIVDQQK--------------------READERKKKEAAE-------------------AVE-KEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELT-DPDHAWGNEEPEPVSAGGDSSDAVEAY----ALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFV-------TYDPS------------ALEAIA------------------AEEVETDIVAKVI-----VDWTGEDSFSMV---------KGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDE-EEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYV-----------------VPEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPRIKPKKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL----------EAKEGVGPAKDLGN-VEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVKEV 837
S S P + P + P P VL S+ P A W++ ++ KY+ +F D++R GFL G+QAR L+Q+ LPQ LA+IW LSD+D +G+LSCDEF+++ +LCDLA + +P LP D+IPP+FR Q +A + V P + +S +TFEDKR+ENF KGQAELE+RR+++++ Q+ R ERK++E E A+E KE R+E+ERQR +EWE R +EL RQ EQE +L++KAK N+ ++ + D+++ ++ +I + R GV VK+ ID MR++RD +MN+M+ LK +LKDQN+RL+ ++QEK ++E+K S T+ + + N K+ ++Q ++ LEEM+++ ++ + + L K+ L +I C+ L+ +DEKR ++ K RM+ D AW + P + D++ V Y ALY+F N DEL+F+ GD I+V + + EPGWL GE G+ GWFPE++V +Y + LE IA A ++ + +I V+ E ++ + +II + + W +G+ G+FP + P+ E V D DS E ++A PYQS E GDL F + + I V K +WWTG DD+ G+FPSNYV +P+ + AP PP SQ+E S A P + + K K E+A V+APY+ATS EQLSL RG+ I+IRKK +GWW+GE Q KGKKRQIGWFPASYVK+L +++E K +G+ ALFDY DE+SFK+ D+I ++SK++ WW+G+L + G+FP NY++ +
Sbjct: 281 GSLVSPPGIPLAPTKTSPPGAPGVLEKLSSLDSPPPAVQAPVEWSVPHASKLKYTQLFNTHDRTRCGFLSGVQARGLLVQSQLPQADLAKIWDLSDMDSDGQLSCDEFVLAMHLCDLARSKQKIPSPLPIDLIPPAFR----RQRQNSVSANNDVPDPLAG-----ISQTTFEDKRKENFEKGQAELERRRKALLEIQRKEQEERERKEREEAEKREKLRLEQERKRQEEFEKQMQRQREIEEAKEEERRRALEQKEAARREMERQRQLEWEKQRIQELEQQRQKEQEAVLRMKAKNQNLTIELQQLNDKVRELSRKIGDTRAGVTGVKTTIDGMRTTRDTQMNEMSTLKAKLKDQNQRLIVLSQEKLRLEAKNKLNQSSTDAAAQEQAKIALNNKQIALKQLREKLEEMEKEVKSKEEDINNNNTQLSELKDQLRSLIAECEDLFIVYDEKRNKVLELKGNRMKSYNWSTDAAW---DSAPTTWSEDTTVEVSNYRKYRALYEFVARNGDELSFQPGDVIMVPISQNAEPGWLAGELRGQTGWFPESYVEPLEANDSYSTANGHTDDAVTLNRPLEGIAEVPENLSDAGSGIEAAEGAPPIQNEDANPIIGLGTAVNLKAEALYTFIARKNTHLNFNKGDIIAVSENQDSWWYGECNGQ--SGWFPKNYVKAIPEAVEPVAVDYGT--ADSGLQEYYIAVYPYQSVEVGDLSFNQDEIILVTKKEGDWWTGTIDDRTGIFPSNYVQKYEAPPEVKPVTSSSPMPDSYSAAPTTT--PPILSQLEPQKTGGSSRAVTP--------DFSAFASSQKTKAGKKPEIATVIAPYQATSAEQLSLQRGEFIMIRKKTTTGWWEGERQ-AKGKKRQIGWFPASYVKILGEGGRKGSVSKSEERTPEVKAVGDKFIALFDYSALNDDEVSFKKDDVITIISKDEQAWWKGELNGKVGLFPSNYLEAL 1215
BLAST of intersectin-1 isoform x2 vs. nr
Match: gi|1229894803|ref|XP_022167949.1| (intersectin-1 [Myzus persicae]) HSP 1 Score: 503.442 bits (1295), Expect = 5.765e-155 Identity = 340/969 (35.09%), Postives = 502/969 (51.81%), Query Frame = 0
Query: 12 VTPALSHAPVPVVLPVSSA---ASVGTPGSTAGGAWNIAEGTRSKYSNIFFQMDKSRVGFLGGIQARNTLLQTGLPQNVLAQIWTLSDIDGNGKLSCDEFIVSGYLCDLATKGEPLPGKLPSDIIPPSFRPFPAPGPQIVSTAGSTVSTPGSSRAES---VVSPSTFEDKRRENFNKGQAELEKRRQSIVD--------------------------QQKREADE-----RKKKEAAEAV---------EKEKQRQELERQRIMEWEDNRKKELNSHRQNEQEKLLQLKAKQTNIKDDMDKSRDRIKHITEEIANCRTGVADVKSFIDTMRSSRDEKMNKMNALKQQLKDQNERLLKVTQEKAQMESKKAALASQTNGEQITEFEFRRNEKKKKVEQTQKLLEEMKEKFETIKGEKEAKRESLDGHKESLIQIIEACKTLYDSFDEKRREIKAEKSKRMRELTD-PDHAWGNEEP------EPVSAGGDSSDAVEAYALYDFEPSNEDELAFKTGDKIIVHKNLDPEPGWLGGEFNGKAGWFPETFV-TYDPS-----------------------ALEAIA-------AEEVETD------------------IVAKVIVDWTGEDS--FSMVKGAEIIVIGRPTEEWCFGKVKDTEACGFFPSVILSVNPDEEEVNTDELVLPTDSLPTEVFVAHVPYQSTEPGDLVFEEGQKIRVLVKNSEWWTGQYDDKLGVFPSNYVV---PEGEAGAPNAEAPPPGESQVEASAPVESEDAANPPPANPDESNAPR-IKP------------------KKVKKDDKTMELAKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLL------------EAKEGVGPA--------KDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYV 834
V PAL AP PV+S S+ +PG+ W + T+ KY+ IF D++R GFL G+QAR ++ T LPQNVLAQIW LSD+D +G+L CDEF+++ YLCDLA GE + LP ++IPPS R ++++ P ES +++ +TFEDKR+ENF KGQAELE+RR+++++ Q+KR DE RK+KE + ++E R+E+ERQR +EWE R EL RQ EQE +L+LK K ++ D+ + D+++ ++++I+ R V VKS ID+MR++RD +MN+M+ LK LK+QN+RL+ V+QEK ++E+K E + + KK + Q ++++ + E K + E ++D K L +++E C+ +Y S++E +++ K + +E++ D AW N P E ++ +SS + ALY+FE N DEL+F+ GD I+V + EPGWL GE K GWFPE++V T D S LE IA + ETD I A+V+ DWTG+DS S+V G EII + ++W +GK D F S + + ++ N +P+D E ++ PY+S EPGDL + + + V K+ +WWTG D+ G+FPSNYV P+ + N P S V++ V S P P + + R + P K+ K K E+A V+APY ATSTEQLSL RGQ++ IRKK +GWW+GE+Q KG+KRQIGWFPASYVK L + V P V ALF + +DEL+F++ +II L+SK++ WWRG+L ++G+FP NYV
Sbjct: 185 VKPALPAAPSLPGTPVASMPMPISIDSPGNQE---WAVPHQTKLKYTQIFNTTDRTRTGFLTGVQARGIMVATQLPQNVLAQIWNLSDMDKDGQLCCDEFVLAMYLCDLAKSGEKIRIPLPPELIPPSVR----------RQRQNSLTAPSEGTPESDSCLINQTTFEDKRKENFEKGQAELERRRKALLEIQRKEQEERERKEREEQDRREKIRLEQEKRRQDELEIQMRKQKELEQEREEQRKRAQEQREAARKEMERQRQLEWEKQRSMELQQQRQKEQETVLKLKGKNQSLTIDLQQMTDKVRELSQKISETRASVTGVKSTIDSMRTTRDTQMNEMSRLKSTLKEQNQRLITVSQEKVRLEAKNKMNHGIETAETQEQTQSAVANKKLAFKSLQDKIDDLNSQIELKKQDVENNNSTVDQLKTQLTKLVEDCEKIYPSYEENTKKVLEMKKSKAKEMSSWGDDAW-NSAPTTDWVEEKSASTLESSAHKKCRALYEFEARNTDELSFQPGDIIMVPLEQNAEPGWLTGELKNKTGWFPESYVETVDGSDDIRDIIANRQAPLEDNFISTQKPLEGIAELPENEPGQGFETDEFSTSYPKLTLGLGKSVNIKAQVLNDWTGKDSNYLSLVAG-EIIDVTENQDDWWYGKTSDNRVGWFQKSSVSIIENAVKDTN-----IPSDK--QEYYIVLYPYESVEPGDLNMNQDEVVLVTKKDGDWWTGIIGDRSGIFPSNYVQYLDPQPKETTVNKNPPFETASSVKSETSVTSSPLTTPIMLEPQKPDGSRSVTPDLASTKRESSATEDSENDDKITKGTKKAEVATVIAPYTATSTEQLSLQRGQLVKIRKKTTTGWWEGELQ-AKGQKRQIGWFPASYVKPLGNTGRANSPATKSNQSAVMPVTTPTPSSNNTQEKVIALFPFNAVHNDELTFQKDEIITLVSKDEQAWWRGELNGKTGLFPSNYV 1130 HSP 2 Score: 81.2629 bits (199), Expect = 7.794e-12 Identity = 69/244 (28.28%), Postives = 117/244 (47.95%), Query Frame = 0
Query: 607 YQSTEPGDLVFEEGQKIRV-LVKNSE--WWTGQYDDKLGVFPSNYVVPEGEAGA-------PNAEAPPPGESQVEASAPVE--SEDAANPPPANPDESNAPRIKPKKVKKDDKTMEL-AKVVAPYEATSTEQLSLTRGQMIIIRKKADSGWWQGEVQGGKGKKRQIGWFPASYVKLLE--AKEGVGPAKDLGNVEALFDYEGARSDELSFKQGDIIELLSKEDGDWWRGKLETESGMFPCNYVK 835
+++ +L F+ G I V L +N+E W TG+ +K G FP +YV E G+ N +AP ++ + P+E +E N P + PK K++ + A+V+ + + LSL G++I + + D W+ GK ++GWF S V ++E K+ P+ L+ YE +L+ Q +++ L++K+DGDWW G + SG+FP NYV+
Sbjct: 672 FEARNTDELSFQPGDIIMVPLEQNAEPGWLTGELKNKTGWFPESYV--ETVDGSDDIRDIIANRQAPLE-DNFISTQKPLEGIAELPENEPGQGFETDEFSTSYPKLTLGLGKSVNIKAQVLNDWTGKDSNYLSLVAGEIIDVTENQDDWWY------GKTSDNRVGWFQKSSVSIIENAVKDTNIPSDKQEYYIVLYPYESVEPGDLNMNQDEVV-LVTKKDGDWWTGIIGDRSGIFPSNYVQ 905 The following BLAST results are available for this feature:
BLAST of intersectin-1 isoform x2 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 17
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BLAST of intersectin-1 isoform x2 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of intersectin-1 isoform x2 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold96_size378025:369371..372769- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold96_size378025-snap-gene-2.51 ID=maker-scaffold96_size378025-snap-gene-2.51|Name=intersectin-1 isoform x2|organism=Tigriopus kingsejongensis|type=gene|length=3399bp|location=Sequence derived from alignment at scaffold96_size378025:369371..372769- (Tigriopus kingsejongensis)back to top Synonyms
The feature 'intersectin-1 isoform x2' has the following synonyms
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