Protein

## EMLSAP00000011487

Length
2,358 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   15 - 336
   - Ankyrin repeat-containing domain (IPR020683)
   376 - 469
   - Ankyrin repeat-containing domain (IPR020683)
   943 - 1,083
   - Mitochondrial Rho-like (IPR013684)
   1,682 - 1,989
   - Protein kinase-like domain (IPR011009)
     - Protein kinase domain (IPR000719)
       - Serine/threonine- /dual specificity protein kinase, catalytic domain (IPR002290)
   2,042 - 2,318
   - WD40/YVTN repeat-like-containing domain (IPR015943)
     - WD40-repeat-containing domain (IPR017986)
2. Domain
   935 - 1,147
   - ROC GTPase (IPR020859)
3. Domain
   941 - 1,148
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
4. Repeat
   46 - 75
   - Ankyrin repeat (IPR002110)
   82 - 114
   - Ankyrin repeat (IPR002110)
   115 - 144
   - Ankyrin repeat (IPR002110)
   178 - 207
   - Ankyrin repeat (IPR002110)
   211 - 241
   - Ankyrin repeat (IPR002110)
   245 - 276
   - Ankyrin repeat (IPR002110)
   299 - 328
   - Ankyrin repeat (IPR002110)
   376 - 405
   - Ankyrin repeat (IPR002110)
   413 - 443
   - Ankyrin repeat (IPR002110)
   549 - 572
   - Leucine-rich repeat, typical subtype (IPR003591)
   581 - 604
   - Leucine-rich repeat, typical subtype (IPR003591)
   605 - 627
   - Leucine-rich repeat, typical subtype (IPR003591)
   628 - 650
   - Leucine-rich repeat, typical subtype (IPR003591)
   723 - 746
   - Leucine-rich repeat, typical subtype (IPR003591)
   747 - 770
   - Leucine-rich repeat, typical subtype (IPR003591)
   771 - 793
   - Leucine-rich repeat, typical subtype (IPR003591)
   821 - 844
   - Leucine-rich repeat, typical subtype (IPR003591)
   847 - 870
   - Leucine-rich repeat, typical subtype (IPR003591)
5. Repeat
   528 - 549
   - Leucine-rich repeat (IPR001611)
   551 - 572
   - Leucine-rich repeat (IPR001611)
   583 - 604
   - Leucine-rich repeat (IPR001611)
   606 - 627
   - Leucine-rich repeat (IPR001611)
   629 - 650
   - Leucine-rich repeat (IPR001611)
   725 - 746
   - Leucine-rich repeat (IPR001611)
   749 - 770
   - Leucine-rich repeat (IPR001611)
   772 - 793
   - Leucine-rich repeat (IPR001611)
   823 - 844
   - Leucine-rich repeat (IPR001611)
   849 - 870
   - Leucine-rich repeat (IPR001611)
   872 - 894
   - Leucine-rich repeat (IPR001611)

1 500 1000 1500 2000 2358

### Detailed signature matches

1. IPR020683
   Ankyrin repeat-containing domain
   1. PS50297 (ANK_REP_RE...)
      376 - 445
      PROSITE profiles
      PS50297 (ANK_REP_REGION)
      15 - 267
      PROSITE profiles
      PS50297 (ANK_REP_REGION)
   2. G3DSA:1.25.40.20
      378 - 469
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
      150 - 336
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
      15 - 138
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
   3. PF12796 (Ank_2)
      51 - 138
      Pfam
      PF12796 (Ank_2)
      246 - 322
      Pfam
      PF12796 (Ank_2)
      153 - 233
      Pfam
      PF12796 (Ank_2)
      377 - 439
      Pfam
      PF12796 (Ank_2)
   4. SSF48403 (Ankyrin r...)
      377 - 439
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
      291 - 332
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
      15 - 325
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
2. IPR020859
   ROC GTPase
   1. PS51424 (ROC)
      935 - 1,147
      PROSITE profiles
      PS51424 (ROC)
3. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      941 - 1,148
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
4. IPR013684
   Mitochondrial Rho-like
   1. PF08477 (Miro)
      943 - 1,083
      Pfam
      PF08477 (Miro)
5. IPR011009
   Protein kinase-like domain
   1. SSF56112 (Protein k...)
      1,758 - 1,983
      SUPERFAMILY
      SSF56112 (Protein kinase-like (PK-like))
      1,682 - 1,731
      SUPERFAMILY
      SSF56112 (Protein kinase-like (PK-like))
6. IPR000719
   Protein kinase domain
   1. PF00069 (Pkinase)
      1,691 - 1,980
      Pfam
      PF00069 (Pkinase)
   2. PS50011 (PROTEIN_KI...)
      1,689 - 1,989
      PROSITE profiles
      PS50011 (PROTEIN_KINASE_DOM)
7. IPR002290
   Serine/threonine- /dual specificity protein kinase, catalytic domain
   1. SM00220 (S_TKc)
      1,689 - 1,988
      SMART
      SM00220 (S_TKc)
8. IPR015943
   WD40/YVTN repeat-like-containing domain
   1. G3DSA:2.130.1...
      2,042 - 2,318
      GENE3D
      G3DSA:2.130.10.10 (G3DSA:2.130.10.10)
9. IPR017986
   WD40-repeat-containing domain
   1. SSF50978 (WD40 repe...)
      2,042 - 2,318
      SUPERFAMILY
      SSF50978 (WD40 repeat-like)
10. IPR002110
    Ankyrin repeat
    1. SM00248 (ANK)
       82 - 111
       SMART
       SM00248 (ANK)
       376 - 405
       SMART
       SM00248 (ANK)
       413 - 443
       SMART
       SM00248 (ANK)
       178 - 207
       SMART
       SM00248 (ANK)
       245 - 276
       SMART
       SM00248 (ANK)
       211 - 241
       SMART
       SM00248 (ANK)
       46 - 75
       SMART
       SM00248 (ANK)
       115 - 144
       SMART
       SM00248 (ANK)
       299 - 328
       SMART
       SM00248 (ANK)
    2. PS50088 (ANK_REPEAT)
       82 - 114
       PROSITE profiles
       PS50088 (ANK_REPEAT)
       245 - 267
       PROSITE profiles
       PS50088 (ANK_REPEAT)
       376 - 404
       PROSITE profiles
       PS50088 (ANK_REPEAT)
11. IPR001611
    Leucine-rich repeat
    1. PS51450 (LRR)
       872 - 894
       PROSITE profiles
       PS51450 (LRR)
       528 - 549
       PROSITE profiles
       PS51450 (LRR)
       849 - 870
       PROSITE profiles
       PS51450 (LRR)
       749 - 770
       PROSITE profiles
       PS51450 (LRR)
       629 - 650
       PROSITE profiles
       PS51450 (LRR)
       823 - 844
       PROSITE profiles
       PS51450 (LRR)
       772 - 793
       PROSITE profiles
       PS51450 (LRR)
       583 - 604
       PROSITE profiles
       PS51450 (LRR)
       606 - 627
       PROSITE profiles
       PS51450 (LRR)
       725 - 746
       PROSITE profiles
       PS51450 (LRR)
       551 - 572
       PROSITE profiles
       PS51450 (LRR)
12. IPR003591
    Leucine-rich repeat, typical subtype
    1. SM00369 (LRR_TYP)
       771 - 793
       SMART
       SM00369 (LRR_TYP)
       747 - 770
       SMART
       SM00369 (LRR_TYP)
       847 - 870
       SMART
       SM00369 (LRR_TYP)
       628 - 650
       SMART
       SM00369 (LRR_TYP)
       821 - 844
       SMART
       SM00369 (LRR_TYP)
       723 - 746
       SMART
       SM00369 (LRR_TYP)
       605 - 627
       SMART
       SM00369 (LRR_TYP)
       549 - 572
       SMART
       SM00369 (LRR_TYP)
       581 - 604
       SMART
       SM00369 (LRR_TYP)
13. IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
       1,695 - 1,722
       PROSITE patterns
       PS00107 (PROTEIN_KINASE_ATP)
14. IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
       1,839 - 1,851
       PROSITE patterns
       PS00108 (PROTEIN_KINASE_ST)

no IPR
Unintegrated signatures

1. G3DSA:1.10.51...
   1,783 - 1,980
   GENE3D
   G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
2. G3DSA:3.30.20...
   1,680 - 1,782
   GENE3D
   G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
3. G3DSA:3.30.70...
   941 - 1,038
   GENE3D
   G3DSA:3.30.70.1390 (G3DSA:3.30.70.1390)
4. G3DSA:3.40.50...
   1,040 - 1,149
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
5. G3DSA:3.80.10.10
   520 - 644
   GENE3D
   G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
   716 - 909
   GENE3D
   G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
6. PF13504 (LRR_7)
   551 - 566
   Pfam
   PF13504 (LRR_7)
7. PF13855 (LRR_8)
   725 - 783
   Pfam
   PF13855 (LRR_8)
   582 - 640
   Pfam
   PF13855 (LRR_8)
8. PTHR23257 (SERINE-T...)
   17 - 1,991
   PANTHER
   PTHR23257 (SERINE-THREONINE PROTEIN KINASE)
9. PTHR23257:SF88 (LEU...)
   17 - 1,991
   PANTHER
   PTHR23257:SF88 (LEUCINE-RICH REPEATS, RAS-LIKE DOMAIN, KINASE PROTEIN)
10. SM00364 (LRR_BAC)
    549 - 568
    SMART
    SM00364 (LRR_BAC)
    627 - 645
    SMART
    SM00364 (LRR_BAC)
    604 - 623
    SMART
    SM00364 (LRR_BAC)
    770 - 789
    SMART
    SM00364 (LRR_BAC)
    526 - 545
    SMART
    SM00364 (LRR_BAC)
    581 - 600
    SMART
    SM00364 (LRR_BAC)
    870 - 890
    SMART
    SM00364 (LRR_BAC)
    747 - 766
    SMART
    SM00364 (LRR_BAC)
    847 - 866
    SMART
    SM00364 (LRR_BAC)
11. SSF52058 (L domain-...)
    519 - 675
    SUPERFAMILY
    SSF52058 (L domain-like)
    724 - 912
    SUPERFAMILY
    SSF52058 (L domain-like)

### GO term prediction

#### Biological Process

GO:0006468 protein phosphorylation
GO:0007264 small GTPase mediated signal transduction

#### Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups

#### Cellular Component

GO:0005622 intracellular