Protein

## EMLSAP00000010863

Length
653 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   12 - 154
   - Pre-ATP-grasp domain (IPR016185)
     - Carbamoyl-phosphate synthase, large subunit, N-terminal (IPR005481)
   155 - 227
   - ATP-grasp fold, subdomain 1 (IPR013815)
   228 - 458
   - ATP-grasp fold, subdomain 2 (IPR013816)
2. Domain
   16 - 455
   - Biotin carboxylation domain (IPR011764)
   608 - 653
   - Biotin/lipoyl attachment (IPR000089)
3. Domain
   141 - 347
   - ATP-grasp fold (IPR011761)
     - Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain (IPR005479)
   356 - 457
   - Rudiment single hybrid motif (IPR011054)
     - Biotin carboxylase, C-terminal (IPR005482)
   600 - 652
   - Single hybrid motif (IPR011053)

1 100 200 300 400 500 600 653

### Detailed signature matches

1. IPR016185
   Pre-ATP-grasp domain
   1. SSF52440 (PreATP-gr...)
      12 - 138
      SUPERFAMILY
      SSF52440 (PreATP-grasp domain)
   2. G3DSA:3.40.50.20
      17 - 154
      GENE3D
      G3DSA:3.40.50.20 (G3DSA:3.40.50.20)
2. IPR011764
   Biotin carboxylation domain
   1. PS50979 (BC)
      16 - 455
      PROSITE profiles
      PS50979 (BC)
3. IPR005481
   Carbamoyl-phosphate synthase, large subunit, N-terminal
   1. PF00289 (CPSase_L_c...)
      17 - 135
      Pfam
      PF00289 (CPSase_L_chain)
4. IPR011761
   ATP-grasp fold
   1. PS50975 (ATP_GRASP)
      145 - 342
      PROSITE profiles
      PS50975 (ATP_GRASP)
5. IPR005479
   Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
   1. PF02786 (CPSase_L_D2)
      141 - 347
      Pfam
      PF02786 (CPSase_L_D2)
6. IPR013815
   ATP-grasp fold, subdomain 1
   1. G3DSA:3.30.14...
      155 - 227
      GENE3D
      G3DSA:3.30.1490.20 (G3DSA:3.30.1490.20)
7. IPR013816
   ATP-grasp fold, subdomain 2
   1. G3DSA:3.30.47...
      228 - 458
      GENE3D
      G3DSA:3.30.470.20 (G3DSA:3.30.470.20)
8. IPR011054
   Rudiment single hybrid motif
   1. SSF51246 (Rudiment ...)
      356 - 457
      SUPERFAMILY
      SSF51246 (Rudiment single hybrid motif)
9. IPR005482
   Biotin carboxylase, C-terminal
   1. PF02785 (Biotin_carb_C)
      361 - 421
      Pfam
      PF02785 (Biotin_carb_C)
   2. SM00878 (Biotin_carb_C)
      361 - 451
      SMART
      SM00878 (Biotin_carb_C)
10. IPR011053
    Single hybrid motif
    1. SSF51230 (Single hy...)
       600 - 652
       SUPERFAMILY
       SSF51230 (Single hybrid motif)
11. IPR000089
    Biotin/lipoyl attachment
    1. PF00364 (Biotin_lipoyl)
       608 - 653
       Pfam
       PF00364 (Biotin_lipoyl)
12. IPR001882
    Biotin-binding site
    1. PS00188 (BIOTIN)
       628 - 645
       PROSITE patterns
       PS00188 (BIOTIN)

no IPR
Unintegrated signatures

1. G3DSA:2.40.50...
   607 - 653
   GENE3D
   G3DSA:2.40.50.100 (G3DSA:2.40.50.100)
2. PTHR18866 (CARBOXYL...)
   5 - 653
   PANTHER
   PTHR18866 (CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE)
3. PTHR18866:SF17 (MET...)
   5 - 653
   PANTHER
   PTHR18866:SF17 (METHYLCROTONOYL-COA CARBOXYLASE ALPHA CHAIN)
4. SSF56059 (Glutathio...)
   108 - 372
   SUPERFAMILY
   SSF56059 (Glutathione synthetase ATP-binding domain-like)

### GO term prediction

#### Biological Process

GO:0008152 metabolic process

#### Molecular Function

GO:0003824 catalytic activity
GO:0004075 biotin carboxylase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding

#### Cellular Component

None predicted.