Protein

## EMLSAP00000003826

Length
397 amino acids

### Protein family membership

- Protein vav (IPR028530)

### Domains and repeats

1. Domain
   106 - 307
   - Dbl homology (DH) domain (IPR000219)
   313 - 377
   - Pleckstrin homology-like domain (IPR011993)

1 50 100 150 200 250 300 350 397

### Detailed signature matches

1. IPR028530
   Protein vav
   1. PTHR22826:SF53 (VAV...)
      1 - 397
      PANTHER
      PTHR22826:SF53 (VAV PROTEIN)
2. IPR000219
   Dbl homology (DH) domain
   1. SM00325 (RhoGEF)
      112 - 285
      SMART
      SM00325 (RhoGEF)
   2. SSF48065 (DBL homol...)
      106 - 307
      SUPERFAMILY
      SSF48065 (DBL homology domain (DH-domain))
   3. PF00621 (RhoGEF)
      112 - 285
      Pfam
      PF00621 (RhoGEF)
   4. G3DSA:1.20.90...
      107 - 305
      GENE3D
      G3DSA:1.20.900.10 (G3DSA:1.20.900.10)
   5. PS50010 (DH_2)
      108 - 286
      PROSITE profiles
      PS50010 (DH_2)
3. IPR011993
   Pleckstrin homology-like domain
   1. G3DSA:2.30.29.30
      313 - 377
      GENE3D
      G3DSA:2.30.29.30 (G3DSA:2.30.29.30)

no IPR
Unintegrated signatures

1. PTHR22826 (RHO GUAN...)
   1 - 397
   PANTHER
   PTHR22826 (RHO GUANINE EXCHANGE FACTOR-RELATED)
2. SSF50729 (PH domain...)
   295 - 380
   SUPERFAMILY
   SSF50729 (PH domain-like)

### GO term prediction

#### Biological Process

GO:0007264 small GTPase mediated signal transduction
GO:0035023 regulation of Rho protein signal transduction

#### Molecular Function

GO:0005089 Rho guanyl-nucleotide exchange factor activity

#### Cellular Component

None predicted.