Protein

## EMLSAP00000008711

Length
412 amino acids

### Protein family membership

- ADF/Cofilin/Destrin (IPR017904)

### Domains and repeats

1. Domain
   1 - 267
   - Actin-binding, cofilin/tropomyosin type (IPR002108)

1 50 100 150 200 250 300 350 412

### Detailed signature matches

1. IPR017904
   ADF/Cofilin/Destrin
   1. PTHR11913 (COFILIN-...)
      1 - 154
      PANTHER
      PTHR11913 (COFILIN-RELATED)
2. IPR002108
   Actin-binding, cofilin/tropomyosin type
   1. SM00102 (ADF)
      133 - 266
      SMART
      SM00102 (ADF)
      8 - 132
      SMART
      SM00102 (ADF)
   2. PS51263 (ADF_H)
      134 - 267
      PROSITE profiles
      PS51263 (ADF_H)
      1 - 142
      PROSITE profiles
      PS51263 (ADF_H)
   3. PF00241 (Cofilin_ADF)
      9 - 128
      Pfam
      PF00241 (Cofilin_ADF)
      134 - 262
      Pfam
      PF00241 (Cofilin_ADF)

no IPR
Unintegrated signatures

1. G3DSA:3.40.20.10
   1 - 126
   GENE3D
   G3DSA:3.40.20.10 (G3DSA:3.40.20.10)
   127 - 255
   GENE3D
   G3DSA:3.40.20.10 (G3DSA:3.40.20.10)
2. SSF55753 (Actin dep...)
   1 - 128
   SUPERFAMILY
   SSF55753 (Actin depolymerizing proteins)
   126 - 255
   SUPERFAMILY
   SSF55753 (Actin depolymerizing proteins)

### GO term prediction

#### Biological Process

GO:0030042 actin filament depolymerization

#### Molecular Function

GO:0003779 actin binding

#### Cellular Component

GO:0005622 intracellular
GO:0015629 actin cytoskeleton