Protein

## EMLSAP00000001390

Length
891 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   48 - 116
   - GRAM domain (IPR004182)
   212 - 465
   - Rab-GTPase-TBC domain (IPR000195)
   631 - 666
   - EF-hand domain (IPR002048)
2. Domain
   585 - 676
   - EF-hand domain pair (IPR011992)

1 100 200 300 400 500 600 700 800 891

### Detailed signature matches

1. IPR004182
   GRAM domain
   1. SM00568 (GRAM)
      48 - 116
      SMART
      SM00568 (GRAM)
   2. PF02893 (GRAM)
      49 - 114
      Pfam
      PF02893 (GRAM)
2. IPR000195
   Rab-GTPase-TBC domain
   1. SSF47923 (Ypt/Rab-G...)
      368 - 465
      SUPERFAMILY
      SSF47923 (Ypt/Rab-GAP domain of gyp1p)
      212 - 386
      SUPERFAMILY
      SSF47923 (Ypt/Rab-GAP domain of gyp1p)
   2. PS50086 (TBC_RABGAP)
      240 - 427
      PROSITE profiles
      PS50086 (TBC_RABGAP)
   3. SM00164 (TBC)
      237 - 450
      SMART
      SM00164 (TBC)
   4. PF00566 (RabGAP-TBC)
      244 - 446
      Pfam
      PF00566 (RabGAP-TBC)
3. IPR011992
   EF-hand domain pair
   1. G3DSA:1.10.23...
      585 - 676
      GENE3D
      G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
4. IPR002048
   EF-hand domain
   1. PS50222 (EF_HAND_2)
      631 - 666
      PROSITE profiles
      PS50222 (EF_HAND_2)
5. IPR018247
   EF-Hand 1, calcium-binding site
   1. PS00018 (EF_HAND_1)
      644 - 656
      PROSITE patterns
      PS00018 (EF_HAND_1)

no IPR
Unintegrated signatures

1. Coil
   1 - 22
   COILS
   Coil (Coil)
2. G3DSA:1.10.8.270
   232 - 352
   GENE3D
   G3DSA:1.10.8.270 (G3DSA:1.10.8.270)
3. PTHR22957 (TBC1 DOM...)
   1 - 611
   PANTHER
   PTHR22957 (TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN)
4. PTHR22957:SF94 (TBC...)
   1 - 611
   PANTHER
   PTHR22957:SF94 (TBC DOMAIN CONTAINING PROTEIN)
5. SSF47473 (EF-hand)
   626 - 676
   SUPERFAMILY
   SSF47473 (EF-hand)

### GO term prediction

#### Biological Process

GO:0032313 regulation of Rab GTPase activity

#### Molecular Function

GO:0005097 Rab GTPase activator activity
GO:0005509 calcium ion binding

#### Cellular Component

None predicted.