Protein

## EMLSAP00000012949

Length
5,071 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   426 - 705
   - Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II (IPR009091)
   2,583 - 2,660
   - CPH domain (IPR021097)
   2,735 - 2,781
   - Zinc finger, ZZ-type (IPR000433)
   2,815 - 2,950
   - Galactose-binding domain-like (IPR008979)
   2,987 - 3,355
   - Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II (IPR009091)
   3,991 - 4,312
   - Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II (IPR009091)
2. Domain
   1,187 - 1,269
   - Cytochrome b5-like heme/steroid binding domain (IPR001199)
   1,863 - 1,936
   - Mib-herc2 (IPR010606)
   2,580 - 2,659
   - Ribosomal protein L2 domain 2 (IPR014722)
   2,791 - 2,970
   - Anaphase-promoting complex, subunit 10/DOC domain (IPR004939)
   4,436 - 4,749
   - HECT (IPR000569)
   4,787 - 5,068
   - Mitochondrial carrier domain (IPR023395)
3. Repeat
   589 - 639
   - Regulator of chromosome condensation, RCC1 (IPR000408)
   2,989 - 3,040
   - Regulator of chromosome condensation, RCC1 (IPR000408)
   3,200 - 3,356
   - Regulator of chromosome condensation, RCC1 (IPR000408)
   4,075 - 4,127
   - Regulator of chromosome condensation, RCC1 (IPR000408)
   4,203 - 4,254
   - Regulator of chromosome condensation, RCC1 (IPR000408)
   4,255 - 4,306
   - Regulator of chromosome condensation, RCC1 (IPR000408)
   4,787 - 4,878
   - Mitochondrial substrate/solute carrier (IPR018108)
   4,880 - 4,968
   - Mitochondrial substrate/solute carrier (IPR018108)
   4,974 - 5,069
   - Mitochondrial substrate/solute carrier (IPR018108)
4. Repeat
   3,040 - 3,094
   - Regulator of chromosome condensation, RCC1 (IPR000408)
5. Repeat
   3,094 - 3,198
   - Regulator of chromosome condensation, RCC1 (IPR000408)
   4,021 - 4,075
   - Regulator of chromosome condensation, RCC1 (IPR000408)
   4,127 - 4,179
   - Regulator of chromosome condensation, RCC1 (IPR000408)

1 500 1000 1500 2000 2500 3000 3500 4000 4500 5071

### Detailed signature matches

1. IPR009091
   Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
   1. SSF50985 (RCC1/BLIP-II)
      4,151 - 4,312
      SUPERFAMILY
      SSF50985 (RCC1/BLIP-II)
      426 - 695
      SUPERFAMILY
      SSF50985 (RCC1/BLIP-II)
      2,987 - 3,355
      SUPERFAMILY
      SSF50985 (RCC1/BLIP-II)
      3,991 - 4,199
      SUPERFAMILY
      SSF50985 (RCC1/BLIP-II)
   2. G3DSA:2.130.1...
      507 - 705
      GENE3D
      G3DSA:2.130.10.30 (G3DSA:2.130.10.30)
      3,991 - 4,308
      GENE3D
      G3DSA:2.130.10.30 (G3DSA:2.130.10.30)
      2,987 - 3,355
      GENE3D
      G3DSA:2.130.10.30 (G3DSA:2.130.10.30)
2. IPR001199
   Cytochrome b5-like heme/steroid binding domain
   1. PF00173 (Cyt-b5)
      1,192 - 1,261
      Pfam
      PF00173 (Cyt-b5)
   2. G3DSA:3.10.12...
      1,189 - 1,267
      GENE3D
      G3DSA:3.10.120.10 (G3DSA:3.10.120.10)
   3. SSF55856 (Cytochrom...)
      1,187 - 1,269
      SUPERFAMILY
      SSF55856 (Cytochrome b5-like heme/steroid binding domain)
3. IPR010606
   Mib-herc2
   1. PF06701 (MIB_HERC2)
      1,874 - 1,934
      Pfam
      PF06701 (MIB_HERC2)
   2. PS51416 (MIB_HERC2)
      1,863 - 1,936
      PROSITE profiles
      PS51416 (MIB_HERC2)
4. IPR014722
   Ribosomal protein L2 domain 2
   1. G3DSA:2.30.30.30
      2,580 - 2,659
      GENE3D
      G3DSA:2.30.30.30 (G3DSA:2.30.30.30)
5. IPR021097
   CPH domain
   1. PF11515 (Cul7)
      2,583 - 2,660
      Pfam
      PF11515 (Cul7)
6. IPR000433
   Zinc finger, ZZ-type
   1. PS50135 (ZF_ZZ_2)
      2,735 - 2,781
      PROSITE profiles
      PS50135 (ZF_ZZ_2)
   2. SM00291 (ZnF_ZZ)
      2,735 - 2,779
      SMART
      SM00291 (ZnF_ZZ)
   3. PF00569 (ZZ)
      2,736 - 2,777
      Pfam
      PF00569 (ZZ)
7. IPR004939
   Anaphase-promoting complex, subunit 10/DOC domain
   1. PS51284 (DOC)
      2,791 - 2,970
      PROSITE profiles
      PS51284 (DOC)
   2. PF03256 (APC10)
      2,823 - 2,903
      Pfam
      PF03256 (APC10)
8. IPR008979
   Galactose-binding domain-like
   1. G3DSA:2.60.12...
      2,815 - 2,950
      GENE3D
      G3DSA:2.60.120.260 (G3DSA:2.60.120.260)
   2. SSF49785 (Galactose...)
      2,818 - 2,945
      SUPERFAMILY
      SSF49785 (Galactose-binding domain-like)
9. IPR000569
   HECT
   1. SSF56204 (Hect, E3 ...)
      4,436 - 4,727
      SUPERFAMILY
      SSF56204 (Hect, E3 ligase catalytic domain)
   2. SM00119 (HECTc)
      4,446 - 4,749
      SMART
      SM00119 (HECTc)
   3. PS50237 (HECT)
      4,460 - 4,707
      PROSITE profiles
      PS50237 (HECT)
   4. PF00632 (HECT)
      4,482 - 4,709
      Pfam
      PF00632 (HECT)
10. IPR023395
    Mitochondrial carrier domain
    1. G3DSA:1.50.40.10
       4,787 - 5,068
       GENE3D
       G3DSA:1.50.40.10 (G3DSA:1.50.40.10)
    2. SSF103506 (Mitochon...)
       4,787 - 5,066
       SUPERFAMILY
       SSF103506 (Mitochondrial carrier)
11. IPR000408
    Regulator of chromosome condensation, RCC1
    1. PS00626 (RCC1_2)
       3,133 - 3,143
       PROSITE patterns
       PS00626 (RCC1_2)
    2. PR00633 (RCCNDNSATION)
       3,133 - 3,149
       PRINTS
       PR00633 (RCCNDNSATION)
       3,043 - 3,059
       PRINTS
       PR00633 (RCCNDNSATION)
       3,300 - 3,321
       PRINTS
       PR00633 (RCCNDNSATION)
       3,242 - 3,260
       PRINTS
       PR00633 (RCCNDNSATION)
       2,990 - 3,006
       PRINTS
       PR00633 (RCCNDNSATION)
       3,149 - 3,163
       PRINTS
       PR00633 (RCCNDNSATION)
    3. PF00415 (RCC1)
       4,127 - 4,170
       Pfam
       PF00415 (RCC1)
       3,252 - 3,301
       Pfam
       PF00415 (RCC1)
       4,205 - 4,250
       Pfam
       PF00415 (RCC1)
       3,094 - 3,143
       Pfam
       PF00415 (RCC1)
       3,200 - 3,249
       Pfam
       PF00415 (RCC1)
       4,021 - 4,072
       Pfam
       PF00415 (RCC1)
       4,075 - 4,124
       Pfam
       PF00415 (RCC1)
       3,305 - 3,352
       Pfam
       PF00415 (RCC1)
       3,040 - 3,091
       Pfam
       PF00415 (RCC1)
       4,255 - 4,302
       Pfam
       PF00415 (RCC1)
       3,146 - 3,189
       Pfam
       PF00415 (RCC1)
    4. PS50012 (RCC1_3)
       2,989 - 3,040
       PROSITE profiles
       PS50012 (RCC1_3)
       4,128 - 4,179
       PROSITE profiles
       PS50012 (RCC1_3)
       3,095 - 3,146
       PROSITE profiles
       PS50012 (RCC1_3)
       3,201 - 3,252
       PROSITE profiles
       PS50012 (RCC1_3)
       589 - 639
       PROSITE profiles
       PS50012 (RCC1_3)
       4,076 - 4,127
       PROSITE profiles
       PS50012 (RCC1_3)
       3,253 - 3,304
       PROSITE profiles
       PS50012 (RCC1_3)
       4,203 - 4,254
       PROSITE profiles
       PS50012 (RCC1_3)
       3,305 - 3,356
       PROSITE profiles
       PS50012 (RCC1_3)
       4,022 - 4,075
       PROSITE profiles
       PS50012 (RCC1_3)
       3,041 - 3,094
       PROSITE profiles
       PS50012 (RCC1_3)
       4,255 - 4,306
       PROSITE profiles
       PS50012 (RCC1_3)
       3,147 - 3,198
       PROSITE profiles
       PS50012 (RCC1_3)
12. IPR018108
    Mitochondrial substrate/solute carrier
    1. PF00153 (Mito_carr)
       4,974 - 5,069
       Pfam
       PF00153 (Mito_carr)
       4,789 - 4,878
       Pfam
       PF00153 (Mito_carr)
       4,880 - 4,968
       Pfam
       PF00153 (Mito_carr)
    2. PS50920 (SOLCAR)
       4,974 - 5,069
       PROSITE profiles
       PS50920 (SOLCAR)
       4,881 - 4,964
       PROSITE profiles
       PS50920 (SOLCAR)
       4,787 - 4,876
       PROSITE profiles
       PS50920 (SOLCAR)

no IPR
Unintegrated signatures

1. Coil
   948 - 949
   COILS
   Coil (Coil)
   3,938 - 3,959
   COILS
   Coil (Coil)
   936 - 944
   COILS
   Coil (Coil)
   945 - 946
   COILS
   Coil (Coil)
   906 - 907
   COILS
   Coil (Coil)
2. G3DSA:3.30.21...
   4,560 - 4,634
   GENE3D
   G3DSA:3.30.2160.10 (G3DSA:3.30.2160.10)
3. PTHR11254 (HECT DOM...)
   58 - 4,722
   PANTHER
   PTHR11254 (HECT DOMAIN UBIQUITIN-PROTEIN LIGASE)
4. PTHR11254:SF80 (HEC...)
   58 - 4,722
   PANTHER
   PTHR11254:SF80 (HECT DOMAIN AND RCC1-LIKE DOMAIN PROTEIN 2 (HERC2)-RELATED)
5. SSF159034 (Mib/herc...)
   1,868 - 1,934
   SUPERFAMILY
   SSF159034 (Mib/herc2 domain-like)
6. SSF57850 (RING/U-box)
   2,722 - 2,793
   SUPERFAMILY
   SSF57850 (RING/U-box)
7. SSF63748 (Tudor/PWW...)
   2,583 - 2,660
   SUPERFAMILY
   SSF63748 (Tudor/PWWP/MBT)

### GO term prediction

#### Biological Process

GO:0016567 protein ubiquitination

#### Molecular Function

GO:0004842 ubiquitin-protein ligase activity
GO:0008270 zinc ion binding
GO:0020037 heme binding
GO:0046872 metal ion binding

#### Cellular Component

None predicted.