Protein

## EMLSAP00000011521

Length
1,097 amino acids

### Protein family membership

- Chloride channel, voltage gated (IPR001807)

### Domains and repeats

1. Domain
   106 - 427
   - Chloride channel, core (IPR014743)
   462 - 615
   - Chloride channel, core (IPR014743)
   623 - 687
   - CBS domain (IPR000644)
   790 - 1,054
   - Phosphatidic acid phosphatase type 2/haloperoxidase (IPR000326)

1 100 200 300 400 500 600 700 800 900 1000 1097

### Detailed signature matches

1. IPR001807
   Chloride channel, voltage gated
   1. PF00654 (Voltage_CLC)
      174 - 591
      Pfam
      PF00654 (Voltage_CLC)
   2. PR00762 (CLCHANNEL)
      187 - 204
      PRINTS
      PR00762 (CLCHANNEL)
      597 - 611
      PRINTS
      PR00762 (CLCHANNEL)
      504 - 524
      PRINTS
      PR00762 (CLCHANNEL)
      541 - 557
      PRINTS
      PR00762 (CLCHANNEL)
      289 - 308
      PRINTS
      PR00762 (CLCHANNEL)
      559 - 578
      PRINTS
      PR00762 (CLCHANNEL)
2. IPR014743
   Chloride channel, core
   1. SSF81340 (Clc chlor...)
      462 - 613
      SUPERFAMILY
      SSF81340 (Clc chloride channel)
      106 - 424
      SUPERFAMILY
      SSF81340 (Clc chloride channel)
   2. G3DSA:1.10.30...
      110 - 427
      GENE3D
      G3DSA:1.10.3080.10 (G3DSA:1.10.3080.10)
      462 - 615
      GENE3D
      G3DSA:1.10.3080.10 (G3DSA:1.10.3080.10)
3. IPR000644
   CBS domain
   1. PS51371 (CBS)
      627 - 687
      PROSITE profiles
      PS51371 (CBS)
   2. PF00571 (CBS)
      623 - 675
      Pfam
      PF00571 (CBS)
4. IPR000326
   Phosphatidic acid phosphatase type 2/haloperoxidase
   1. SM00014 (acidPPc)
      882 - 1,051
      SMART
      SM00014 (acidPPc)
   2. G3DSA:1.20.14...
      1,013 - 1,051
      GENE3D
      G3DSA:1.20.144.10 (G3DSA:1.20.144.10)
      878 - 976
      GENE3D
      G3DSA:1.20.144.10 (G3DSA:1.20.144.10)
   3. PF01569 (PAP2)
      885 - 1,054
      Pfam
      PF01569 (PAP2)
   4. SSF48317 (Acid phos...)
      1,013 - 1,054
      SUPERFAMILY
      SSF48317 (Acid phosphatase/Vanadium-dependent haloperoxidase)
      790 - 976
      SUPERFAMILY
      SSF48317 (Acid phosphatase/Vanadium-dependent haloperoxidase)

no IPR
Unintegrated signatures

1. G3DSA:3.10.58...
   618 - 748
   GENE3D
   G3DSA:3.10.580.10 (G3DSA:3.10.580.10)
2. PTHR11689 (CHLORIDE...)
   82 - 758
   PANTHER
   PTHR11689 (CHLORIDE CHANNEL)
3. PTHR11689:SF15 (CHL...)
   82 - 758
   PANTHER
   PTHR11689:SF15 (CHLORIDE CHANNEL PROTEIN 7)
4. SSF54631 (CBS-domai...)
   615 - 756
   SUPERFAMILY
   SSF54631 (CBS-domain pair)
5. TMhelix
   482 - 504
   TMHMM
   TMhelix (TMhelix)
   996 - 1,021
   TMHMM
   TMhelix (TMhelix)
   370 - 392
   TMHMM
   TMhelix (TMhelix)
   511 - 533
   TMHMM
   TMhelix (TMhelix)
   160 - 182
   TMHMM
   TMhelix (TMhelix)
   1,036 - 1,058
   TMHMM
   TMhelix (TMhelix)
   283 - 305
   TMHMM
   TMhelix (TMhelix)
   873 - 895
   TMHMM
   TMhelix (TMhelix)
   839 - 861
   TMHMM
   TMhelix (TMhelix)
   564 - 586
   TMHMM
   TMhelix (TMhelix)
   785 - 807
   TMHMM
   TMhelix (TMhelix)
   404 - 426
   TMHMM
   TMhelix (TMhelix)
   953 - 975
   TMHMM
   TMhelix (TMhelix)
   111 - 133
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006821 chloride transport
GO:0055085 transmembrane transport

#### Molecular Function

GO:0003824 catalytic activity
GO:0005216 ion channel activity
GO:0005247 voltage-gated chloride channel activity
GO:0030554 adenyl nucleotide binding

#### Cellular Component

GO:0016020 membrane