Protein

## EMLSAP00000009260

Length
451 amino acids

### Protein family membership

- Aromatic amino acid hydroxylase (IPR001273)
  - Tyrosine 3-monooxygenase-like (IPR019773)

### Domains and repeats

1. Domain
   31 - 111
   - ACT domain (IPR002912)
2. Domain
   103 - 449
   - Aromatic amino acid hydroxylase, C-terminal (IPR019774)

1 50 100 150 200 250 300 350 400 451

### Detailed signature matches

1. IPR001273
   Aromatic amino acid hydroxylase
   1. PTHR11473 (AROMATIC...)
      1 - 451
      PANTHER
      PTHR11473 (AROMATIC AMINO ACID (TYROSINE/TRYPTOPHAN/PHENYLALANINE) HYDROXYLASE)
   2. G3DSA:1.10.80...
      25 - 424
      GENE3D
      G3DSA:1.10.800.10 (G3DSA:1.10.800.10)
2. IPR019773
   Tyrosine 3-monooxygenase-like
   1. PIRSF000336 (TH)
      1 - 451
      PIRSF
      PIRSF000336 (TH)
3. IPR002912
   ACT domain
   1. PS51671 (ACT)
      32 - 111
      PROSITE profiles
      PS51671 (ACT)
   2. PF01842 (ACT)
      31 - 96
      Pfam
      PF01842 (ACT)
4. IPR019774
   Aromatic amino acid hydroxylase, C-terminal
   1. PR00372 (FYWHYDRXLASE)
      235 - 257
      PRINTS
      PR00372 (FYWHYDRXLASE)
      370 - 389
      PRINTS
      PR00372 (FYWHYDRXLASE)
      299 - 318
      PRINTS
      PR00372 (FYWHYDRXLASE)
      144 - 163
      PRINTS
      PR00372 (FYWHYDRXLASE)
      405 - 423
      PRINTS
      PR00372 (FYWHYDRXLASE)
      339 - 357
      PRINTS
      PR00372 (FYWHYDRXLASE)
   2. SSF56534 (Aromatic ...)
      115 - 447
      SUPERFAMILY
      SSF56534 (Aromatic aminoacid monoxygenases, catalytic and oligomerization domains)
   3. PS51410 (BH4_AAA_HY...)
      103 - 449
      PROSITE profiles
      PS51410 (BH4_AAA_HYDROXYL_2)
   4. PF00351 (Biopterin_H)
      116 - 446
      Pfam
      PF00351 (Biopterin_H)
5. IPR018301
   Aromatic amino acid hydroxylase, iron/copper binding site
   1. PS00367 (BH4_AAA_HY...)
      278 - 289
      PROSITE patterns
      PS00367 (BH4_AAA_HYDROXYL_1)

no IPR
Unintegrated signatures

1. Coil
   431 - 452
   COILS
   Coil (Coil)
2. SSF55021 (ACT-like)
   24 - 103
   SUPERFAMILY
   SSF55021 (ACT-like)

### GO term prediction

#### Biological Process

GO:0008152 metabolic process
GO:0009072 aromatic amino acid family metabolic process
GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016597 amino acid binding
GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

#### Cellular Component

None predicted.