Protein

## EMLSAP00000007494

Length
1,126 amino acids

### Protein family membership

- Intersectin-2 (IPR027029)

### Domains and repeats

1. Domain
   2 - 93
   - EF-hand domain pair (IPR011992)
   224 - 329
   - EF-hand domain pair (IPR011992)
2. Domain
   2 - 97
   - EPS15 homology (EH) (IPR000261)
   233 - 329
   - EPS15 homology (EH) (IPR000261)
3. Domain
   41 - 76
   - EF-hand domain (IPR002048)
   273 - 308
   - EF-hand domain (IPR002048)
   639 - 704
   - Src homology-3 domain (IPR001452)
   717 - 777
   - Src homology-3 domain (IPR001452)
   806 - 867
   - Src homology-3 domain (IPR001452)
   968 - 1,044
   - Src homology-3 domain (IPR001452)
   1,068 - 1,126
   - Src homology-3 domain (IPR001452)

1 200 400 600 800 1000 1126

### Detailed signature matches

1. IPR027029
   Intersectin-2
   1. PTHR11216:SF29 (INT...)
      1 - 1,090
      PANTHER
      PTHR11216:SF29 (INTERSECTIN 2)
2. IPR011992
   EF-hand domain pair
   1. G3DSA:1.10.23...
      224 - 329
      GENE3D
      G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
      2 - 93
      GENE3D
      G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
3. IPR000261
   EPS15 homology (EH)
   1. SM00027 (EH)
      233 - 328
      SMART
      SM00027 (EH)
      2 - 96
      SMART
      SM00027 (EH)
   2. PS50031 (EH)
      240 - 329
      PROSITE profiles
      PS50031 (EH)
      9 - 97
      PROSITE profiles
      PS50031 (EH)
4. IPR002048
   EF-hand domain
   1. SM00054 (EFh)
      45 - 73
      SMART
      SM00054 (EFh)
      277 - 305
      SMART
      SM00054 (EFh)
   2. PS50222 (EF_HAND_2)
      41 - 76
      PROSITE profiles
      PS50222 (EF_HAND_2)
      273 - 308
      PROSITE profiles
      PS50222 (EF_HAND_2)
5. IPR001452
   Src homology-3 domain
   1. SM00326 (SH3)
      720 - 776
      SMART
      SM00326 (SH3)
      642 - 699
      SMART
      SM00326 (SH3)
      974 - 1,035
      SMART
      SM00326 (SH3)
      809 - 863
      SMART
      SM00326 (SH3)
      1,071 - 1,126
      SMART
      SM00326 (SH3)
   2. PR00452 (SH3DOMAIN)
      642 - 652
      PRINTS
      PR00452 (SH3DOMAIN)
      1,102 - 1,111
      PRINTS
      PR00452 (SH3DOMAIN)
      823 - 838
      PRINTS
      PR00452 (SH3DOMAIN)
      1,113 - 1,125
      PRINTS
      PR00452 (SH3DOMAIN)
   3. PF00018 (SH3_1)
      812 - 855
      Pfam
      PF00018 (SH3_1)
   4. SSF50044 (SH3-domain)
      718 - 777
      SUPERFAMILY
      SSF50044 (SH3-domain)
      968 - 1,044
      SUPERFAMILY
      SSF50044 (SH3-domain)
      1,069 - 1,125
      SUPERFAMILY
      SSF50044 (SH3-domain)
      806 - 867
      SUPERFAMILY
      SSF50044 (SH3-domain)
      639 - 704
      SUPERFAMILY
      SSF50044 (SH3-domain)
   5. PS50002 (SH3)
      971 - 1,036
      PROSITE profiles
      PS50002 (SH3)
      639 - 700
      PROSITE profiles
      PS50002 (SH3)
      717 - 777
      PROSITE profiles
      PS50002 (SH3)
      1,068 - 1,126
      PROSITE profiles
      PS50002 (SH3)
      806 - 864
      PROSITE profiles
      PS50002 (SH3)
6. IPR018247
   EF-Hand 1, calcium-binding site
   1. PS00018 (EF_HAND_1)
      286 - 298
      PROSITE patterns
      PS00018 (EF_HAND_1)
      54 - 66
      PROSITE patterns
      PS00018 (EF_HAND_1)

no IPR
Unintegrated signatures

1. Coil
   369 - 427
   COILS
   Coil (Coil)
   522 - 571
   COILS
   Coil (Coil)
   435 - 470
   COILS
   Coil (Coil)
2. G3DSA:2.30.30.40
   961 - 1,041
   GENE3D
   G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
   714 - 787
   GENE3D
   G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
   636 - 708
   GENE3D
   G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
   1,050 - 1,125
   GENE3D
   G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
   807 - 864
   GENE3D
   G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
3. PF12763 (EF-hand_4)
   243 - 328
   Pfam
   PF12763 (EF-hand_4)
   5 - 87
   Pfam
   PF12763 (EF-hand_4)
4. PF14604 (SH3_9)
   1,075 - 1,123
   Pfam
   PF14604 (SH3_9)
   978 - 1,032
   Pfam
   PF14604 (SH3_9)
   724 - 773
   Pfam
   PF14604 (SH3_9)
   646 - 696
   Pfam
   PF14604 (SH3_9)
5. PTHR11216 (EH DOMAIN)
   1 - 1,090
   PANTHER
   PTHR11216 (EH DOMAIN)
6. SSF47473 (EF-hand)
   232 - 328
   SUPERFAMILY
   SSF47473 (EF-hand)
   2 - 93
   SUPERFAMILY
   SSF47473 (EF-hand)

### GO term prediction

#### Biological Process

GO:0006897 endocytosis

#### Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

#### Cellular Component

None predicted.