Protein

## EMLSAP00000002076

Length
813 amino acids

### Protein family membership

- Two pore calcium channel protein 1, metazoa (IPR028801)

### Domains and repeats

1. Domain
   130 - 304
   - Ion transport domain (IPR005821)
   483 - 662
   - Ion transport domain (IPR005821)

1 100 200 300 400 500 600 700 813

### Detailed signature matches

1. IPR028801
   Two pore calcium channel protein 1, metazoa
   1. PTHR10037:SF136 (TW...)
      53 - 683
      PANTHER
      PTHR10037:SF136 (TWO PORE CALCIUM CHANNEL PROTEIN 1)
2. IPR005821
   Ion transport domain
   1. PF00520 (Ion_trans)
      483 - 662
      Pfam
      PF00520 (Ion_trans)
      130 - 304
      Pfam
      PF00520 (Ion_trans)

no IPR
Unintegrated signatures

1. G3DSA:1.10.28...
   222 - 314
   GENE3D
   G3DSA:1.10.287.70 (G3DSA:1.10.287.70)
2. PTHR10037 (VOLTAGE-...)
   53 - 683
   PANTHER
   PTHR10037 (VOLTAGE-GATED CATION CHANNEL (CALCIUM AND SODIUM))
3. SSF81324 (Voltage-g...)
   103 - 310
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   634 - 667
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   479 - 575
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
4. TMhelix
   92 - 111
   TMHMM
   TMhelix (TMhelix)
   502 - 524
   TMHMM
   TMhelix (TMhelix)
   452 - 474
   TMHMM
   TMhelix (TMhelix)
   217 - 239
   TMHMM
   TMhelix (TMhelix)
   610 - 629
   TMHMM
   TMhelix (TMhelix)
   251 - 268
   TMHMM
   TMhelix (TMhelix)
   283 - 305
   TMHMM
   TMhelix (TMhelix)
   642 - 664
   TMHMM
   TMhelix (TMhelix)
   163 - 180
   TMHMM
   TMhelix (TMhelix)
   121 - 143
   TMHMM
   TMhelix (TMhelix)
   479 - 498
   TMHMM
   TMhelix (TMhelix)
   545 - 567
   TMHMM
   TMhelix (TMhelix)
   366 - 388
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006811 ion transport
GO:0055085 transmembrane transport

#### Molecular Function

GO:0005216 ion channel activity
GO:0005244 voltage-gated ion channel activity
GO:0072345 NAADP-sensitive calcium-release channel activity

#### Cellular Component

GO:0010008 endosome membrane
GO:0016020 membrane