Protein

## EMLSAP00000001270

Length
300 amino acids

### Protein family membership

- E3 ubiquitin-protein ligase SINA like (IPR004162)

### Domains and repeats

1. Domain
   13 - 87
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)
     - Zinc finger, RING-type (IPR001841)
   88 - 128
   - SIAH-type domain (IPR013323)
2. Domain
   64 - 219
   - TRAF-like (IPR008974)
     - Seven-in-absentia protein, TRAF-like domain (IPR018121)
3. Domain
   74 - 133
   - Zinc finger, SIAH-type (IPR013010)

1 50 100 150 200 250 300 300

### Detailed signature matches

1. IPR004162
   E3 ubiquitin-protein ligase SINA like
   1. PTHR10315 (SEVEN IN...)
      6 - 135
      PANTHER
      PTHR10315 (SEVEN IN ABSENTIA HOMOLOG)
2. IPR013083
   Zinc finger, RING/FYVE/PHD-type
   1. G3DSA:3.30.40.10
      13 - 87
      GENE3D
      G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
3. IPR001841
   Zinc finger, RING-type
   1. PS50089 (ZF_RING_2)
      22 - 57
      PROSITE profiles
      PS50089 (ZF_RING_2)
4. IPR018121
   Seven-in-absentia protein, TRAF-like domain
   1. PF03145 (Sina)
      64 - 219
      Pfam
      PF03145 (Sina)
5. IPR013010
   Zinc finger, SIAH-type
   1. PS51081 (ZF_SIAH)
      74 - 133
      PROSITE profiles
      PS51081 (ZF_SIAH)
6. IPR008974
   TRAF-like
   1. SSF49599 (TRAF doma...)
      75 - 163
      SUPERFAMILY
      SSF49599 (TRAF domain-like)
7. IPR013323
   SIAH-type domain
   1. G3DSA:3.90.89...
      88 - 128
      GENE3D
      G3DSA:3.90.890.10 (G3DSA:3.90.890.10)

no IPR
Unintegrated signatures

1. SSF57850 (RING/U-box)
   16 - 61
   SUPERFAMILY
   SSF57850 (RING/U-box)

### GO term prediction

#### Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007275 multicellular organismal development
GO:0016567 protein ubiquitination

#### Molecular Function

GO:0004842 ubiquitin-protein ligase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding

#### Cellular Component

GO:0005634 nucleus