Protein

## EMLSAP00000009511

Length
441 amino acids

### Protein family membership

- Small GTPase superfamily, ARF type (IPR024156)

- Small GTPase superfamily (IPR001806)
  - Small GTPase superfamily, Rab type (IPR003579)
  - Small GTPase superfamily, Ras type (IPR020849)
  - Small GTPase superfamily, Rho type (IPR003578)

- Ran GTPase (IPR002041)

- Thymidine kinase (IPR001267)

### Domains and repeats

1. Domain
   45 - 216
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   277 - 409
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
2. Domain
   48 - 203
   - Small GTP-binding protein domain (IPR005225)

1 50 100 150 200 250 300 350 400 441

### Detailed signature matches

1. IPR024156
   Small GTPase superfamily, ARF type
   1. SM00177 (ARF)
      38 - 214
      SMART
      SM00177 (ARF)
2. IPR001806
   Small GTPase superfamily
   1. PR00449 (RASTRNSFRMNG)
      188 - 210
      PRINTS
      PR00449 (RASTRNSFRMNG)
      50 - 71
      PRINTS
      PR00449 (RASTRNSFRMNG)
      153 - 166
      PRINTS
      PR00449 (RASTRNSFRMNG)
      91 - 113
      PRINTS
      PR00449 (RASTRNSFRMNG)
      73 - 89
      PRINTS
      PR00449 (RASTRNSFRMNG)
   2. PF00071 (Ras)
      51 - 211
      Pfam
      PF00071 (Ras)
3. IPR020849
   Small GTPase superfamily, Ras type
   1. SM00173 (RAS)
      47 - 213
      SMART
      SM00173 (RAS)
4. IPR003579
   Small GTPase superfamily, Rab type
   1. SM00175 (RAB)
      50 - 213
      SMART
      SM00175 (RAB)
5. IPR003578
   Small GTPase superfamily, Rho type
   1. SM00174 (RHO)
      52 - 216
      SMART
      SM00174 (RHO)
6. IPR002041
   Ran GTPase
   1. SM00176 (RAN)
      55 - 256
      SMART
      SM00176 (RAN)
7. IPR001267
   Thymidine kinase
   1. PF00265 (TK)
      277 - 441
      Pfam
      PF00265 (TK)
8. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      45 - 216
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      277 - 409
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
9. IPR005225
   Small GTP-binding protein domain
   1. TIGR00231
      48 - 203
      UNKNOWN
      TIGR00231 (TIGR00231)

no IPR
Unintegrated signatures

1. G3DSA:3.30.60.20
   410 - 441
   GENE3D
   G3DSA:3.30.60.20 (G3DSA:3.30.60.20)
2. G3DSA:3.40.50...
   42 - 231
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PS51419 (RAB)
   45 - 249
   PROSITE profiles
   PS51419 (RAB)
4. PTHR24073 (FAMILY N...)
   43 - 310
   PANTHER
   PTHR24073 (FAMILY NOT NAMED)
5. PTHR24073:SF24 (SUB...)
   43 - 310
   PANTHER
   PTHR24073:SF24 (SUBFAMILY NOT NAMED)

### GO term prediction

#### Biological Process

GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport

#### Molecular Function

GO:0003924 GTPase activity
GO:0004797 thymidine kinase activity
GO:0005524 ATP binding
GO:0005525 GTP binding

#### Cellular Component

GO:0005622 intracellular
GO:0016020 membrane