Protein

## EMLSAP00000006216

Length
1,295 amino acids

### Protein family membership

- Polyribonucleotide nucleotidyltransferase (IPR012162)

### Domains and repeats

1. Domain
   37 - 128
   - PNPase/RNase PH domain (IPR027408)
   277 - 511
   - PNPase/RNase PH domain (IPR027408)
2. Domain
   37 - 134
   - Ribosomal protein S5 domain 2-type fold (IPR020568)
     - Exoribonuclease, phosphorolytic domain 1 (IPR001247)
   253 - 456
   - Ribosomal protein S5 domain 2-type fold (IPR020568)
     - Exoribonuclease, phosphorolytic domain 1 (IPR001247)
   520 - 586
   - K Homology domain (IPR004087)
     - K Homology domain, type 1 (IPR004088)
3. Domain
   195 - 276
   - Polyribonucleotide nucleotidyltransferase, RNA-binding domain (IPR015848)
   414 - 517
   - Exoribonuclease, phosphorolytic domain 2 (IPR015847)
   586 - 673
   - Nucleic acid-binding, OB-fold (IPR012340)
     - Ribosomal protein S1, RNA-binding domain (IPR003029)

1 200 400 600 800 1000 1295

### Detailed signature matches

1. IPR012162
   Polyribonucleotide nucleotidyltransferase
   1. PTHR11252 (POLYRIBO...)
      38 - 714
      PANTHER
      PTHR11252 (POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE)
2. IPR027408
   PNPase/RNase PH domain
   1. G3DSA:3.30.23...
      37 - 128
      GENE3D
      G3DSA:3.30.230.70 (G3DSA:3.30.230.70)
      277 - 511
      GENE3D
      G3DSA:3.30.230.70 (G3DSA:3.30.230.70)
3. IPR020568
   Ribosomal protein S5 domain 2-type fold
   1. SSF54211 (Ribosomal...)
      37 - 128
      SUPERFAMILY
      SSF54211 (Ribosomal protein S5 domain 2-like)
      253 - 456
      SUPERFAMILY
      SSF54211 (Ribosomal protein S5 domain 2-like)
4. IPR001247
   Exoribonuclease, phosphorolytic domain 1
   1. PF01138 (RNase_PH)
      37 - 134
      Pfam
      PF01138 (RNase_PH)
      285 - 419
      Pfam
      PF01138 (RNase_PH)
5. IPR015848
   Polyribonucleotide nucleotidyltransferase, RNA-binding domain
   1. G3DSA:1.10.10...
      195 - 276
      GENE3D
      G3DSA:1.10.10.400 (G3DSA:1.10.10.400)
6. IPR015847
   Exoribonuclease, phosphorolytic domain 2
   1. SSF55666 (Ribonucle...)
      414 - 517
      SUPERFAMILY
      SSF55666 (Ribonuclease PH domain 2-like)
   2. PF03725 (RNase_PH_C)
      424 - 497
      Pfam
      PF03725 (RNase_PH_C)
7. IPR004087
   K Homology domain
   1. SM00322 (KH)
      520 - 586
      SMART
      SM00322 (KH)
8. IPR004088
   K Homology domain, type 1
   1. PS50084 (KH_TYPE_1)
      521 - 581
      PROSITE profiles
      PS50084 (KH_TYPE_1)
   2. PF00013 (KH_1)
      525 - 581
      Pfam
      PF00013 (KH_1)
9. IPR012340
   Nucleic acid-binding, OB-fold
   1. SSF50249 (Nucleic a...)
      586 - 670
      SUPERFAMILY
      SSF50249 (Nucleic acid-binding proteins)
   2. G3DSA:2.40.50...
      593 - 673
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
10. IPR003029
    Ribosomal protein S1, RNA-binding domain
    1. PS50126 (S1)
       596 - 667
       PROSITE profiles
       PS50126 (S1)

no IPR
Unintegrated signatures

1. Coil
   741 - 762
   COILS
   Coil (Coil)
2. G3DSA:3.30.13...
   521 - 589
   GENE3D
   G3DSA:3.30.1370.10 (G3DSA:3.30.1370.10)
3. SSF54791 (Eukaryoti...)
   519 - 587
   SUPERFAMILY
   SSF54791 (Eukaryotic type KH-domain (KH-domain type I))

### GO term prediction

#### Biological Process

GO:0006396 RNA processing
GO:0006402 mRNA catabolic process

#### Molecular Function

GO:0000175 3'-5'-exoribonuclease activity
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity

#### Cellular Component

None predicted.