Protein

## EMLSAP00000004173

Length
470 amino acids

### Protein family membership

- Mediator complex, subunit Med8, fungi/metazoa (IPR019364)

### Domains and repeats

1. Domain
   251 - 351
   - Nucleotide-binding, alpha-beta plait (IPR012677)
2. Domain
   272 - 351
   - RNA recognition motif domain (IPR000504)

1 50 100 150 200 250 300 350 400 470

### Detailed signature matches

1. IPR019364
   Mediator complex, subunit Med8, fungi/metazoa
   1. PF10232 (Med8)
      6 - 239
      Pfam
      PF10232 (Med8)
2. IPR012677
   Nucleotide-binding, alpha-beta plait
   1. G3DSA:3.30.70...
      251 - 351
      GENE3D
      G3DSA:3.30.70.330 (G3DSA:3.30.70.330)
3. IPR000504
   RNA recognition motif domain
   1. PF00076 (RRM_1)
      280 - 343
      Pfam
      PF00076 (RRM_1)
   2. SM00360 (RRM)
      273 - 347
      SMART
      SM00360 (RRM)
   3. PS50102 (RRM)
      272 - 351
      PROSITE profiles
      PS50102 (RRM)

no IPR
Unintegrated signatures

1. PTHR13074 (FAMILY N...)
   8 - 247
   PANTHER
   PTHR13074 (FAMILY NOT NAMED)
2. SSF54928 (RNA-bindi...)
   267 - 366
   SUPERFAMILY
   SSF54928 (RNA-binding domain, RBD)

### GO term prediction

#### Biological Process

GO:0006357 regulation of transcription from RNA polymerase II promoter

#### Molecular Function

GO:0000166 nucleotide binding
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0003676 nucleic acid binding

#### Cellular Component

GO:0016592 mediator complex