Protein

## EMLSAP00000004441

Length
2,231 amino acids

### Protein family membership

- Gamma thionin (IPR008176)

### Domains and repeats

1. Domain
   67 - 235
   - Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
     - Laminin G domain (IPR001791)
   674 - 811
   - Insulin-like growth factor binding protein, N-terminal (IPR009030)
   1,123 - 1,337
   - Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
     - Laminin G domain (IPR001791)
   1,361 - 1,696
   - Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
     - Laminin G domain (IPR001791)
   1,700 - 1,937
   - Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
     - Laminin G domain (IPR001791)
2. Domain
   69 - 176
   - Concanavalin A-like lectin/glucanases superfamily (IPR008985)
   1,143 - 1,327
   - Concanavalin A-like lectin/glucanases superfamily (IPR008985)
   1,353 - 1,510
   - Concanavalin A-like lectin/glucanases superfamily (IPR008985)
   1,709 - 1,918
   - Concanavalin A-like lectin/glucanases superfamily (IPR008985)
3. Domain
   258 - 298
   - Epidermal growth factor-like domain (IPR000742)
   300 - 339
   - Epidermal growth factor-like domain (IPR000742)
   341 - 377
   - Epidermal growth factor-like domain (IPR000742)
   390 - 428
   - Epidermal growth factor-like domain (IPR000742)
   436 - 488
   - Epidermal growth factor-like domain (IPR000742)
   489 - 522
   - Epidermal growth factor-like domain (IPR000742)
   524 - 562
   - Epidermal growth factor-like domain (IPR000742)
   563 - 597
   - Epidermal growth factor-like domain (IPR000742)
   603 - 639
   - Epidermal growth factor-like domain (IPR000742)
   641 - 685
   - Epidermal growth factor-like domain (IPR000742)
   687 - 723
   - Epidermal growth factor-like domain (IPR000742)
   725 - 764
   - Epidermal growth factor-like domain (IPR000742)
   766 - 803
   - Epidermal growth factor-like domain (IPR000742)
   827 - 863
   - Epidermal growth factor-like domain (IPR000742)
   893 - 930
   - Epidermal growth factor-like domain (IPR000742)
   932 - 968
   - Epidermal growth factor-like domain (IPR000742)
   970 - 1,037
   - Epidermal growth factor-like domain (IPR000742)
   1,039 - 1,074
   - Epidermal growth factor-like domain (IPR000742)
   1,076 - 1,112
   - Epidermal growth factor-like domain (IPR000742)
   1,114 - 1,155
   - Epidermal growth factor-like domain (IPR000742)
   1,329 - 1,365
   - Epidermal growth factor-like domain (IPR000742)
   1,686 - 1,722
   - Epidermal growth factor-like domain (IPR000742)
   1,938 - 1,972
   - Epidermal growth factor-like domain (IPR000742)
   1,974 - 2,009
   - Epidermal growth factor-like domain (IPR000742)
   2,011 - 2,049
   - Epidermal growth factor-like domain (IPR000742)
   2,052 - 2,093
   - Epidermal growth factor-like domain (IPR000742)
   2,095 - 2,154
   - Epidermal growth factor-like domain (IPR000742)
4. Domain
   305 - 339
   - EGF-like calcium-binding domain (IPR001881)
   341 - 377
   - EGF-like calcium-binding domain (IPR001881)
   436 - 488
   - EGF-like calcium-binding domain (IPR001881)
   524 - 562
   - EGF-like calcium-binding domain (IPR001881)
   603 - 639
   - EGF-like calcium-binding domain (IPR001881)
   687 - 723
   - EGF-like calcium-binding domain (IPR001881)
   725 - 764
   - EGF-like calcium-binding domain (IPR001881)
   766 - 803
   - EGF-like calcium-binding domain (IPR001881)
   827 - 863
   - EGF-like calcium-binding domain (IPR001881)
   865 - 930
   - EGF-like calcium-binding domain (IPR001881)
   932 - 968
   - EGF-like calcium-binding domain (IPR001881)
   1,039 - 1,074
   - EGF-like calcium-binding domain (IPR001881)
   1,076 - 1,112
   - EGF-like calcium-binding domain (IPR001881)
   1,329 - 1,365
   - EGF-like calcium-binding domain (IPR001881)
   1,686 - 1,722
   - EGF-like calcium-binding domain (IPR001881)
   1,933 - 1,972
   - EGF-like calcium-binding domain (IPR001881)
   1,974 - 2,009
   - EGF-like calcium-binding domain (IPR001881)
   2,011 - 2,049
   - EGF-like calcium-binding domain (IPR001881)

1 500 1000 1500 2231

### Detailed signature matches

1. IPR008176
   Gamma thionin
   1. PS00940 (GAMMA_THIONIN)
      2,110 - 2,134
      PROSITE patterns
      PS00940 (GAMMA_THIONIN)
2. IPR008985
   Concanavalin A-like lectin/glucanases superfamily
   1. SSF49899 (Concanava...)
      69 - 176
      SUPERFAMILY
      SSF49899 (Concanavalin A-like lectins/glucanases)
      1,143 - 1,327
      SUPERFAMILY
      SSF49899 (Concanavalin A-like lectins/glucanases)
      1,353 - 1,510
      SUPERFAMILY
      SSF49899 (Concanavalin A-like lectins/glucanases)
      1,709 - 1,918
      SUPERFAMILY
      SSF49899 (Concanavalin A-like lectins/glucanases)
3. IPR013320
   Concanavalin A-like lectin/glucanase, subgroup
   1. G3DSA:2.60.12...
      71 - 225
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
      1,686 - 1,696
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
      1,625 - 1,652
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
      1,361 - 1,508
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
      1,700 - 1,909
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
      1,123 - 1,337
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
4. IPR001791
   Laminin G domain
   1. SM00282 (LamG)
      1,395 - 1,648
      SMART
      SM00282 (LamG)
      1,176 - 1,304
      SMART
      SM00282 (LamG)
      1,773 - 1,905
      SMART
      SM00282 (LamG)
      88 - 221
      SMART
      SM00282 (LamG)
   2. PF00054 (Laminin_G_1)
      1,184 - 1,304
      Pfam
      PF00054 (Laminin_G_1)
      1,403 - 1,511
      Pfam
      PF00054 (Laminin_G_1)
   3. PF02210 (Laminin_G_2)
      1,784 - 1,904
      Pfam
      PF02210 (Laminin_G_2)
   4. PS50025 (LAM_G_DOMAIN)
      67 - 235
      PROSITE profiles
      PS50025 (LAM_G_DOMAIN)
      1,369 - 1,690
      PROSITE profiles
      PS50025 (LAM_G_DOMAIN)
      1,750 - 1,937
      PROSITE profiles
      PS50025 (LAM_G_DOMAIN)
      1,157 - 1,327
      PROSITE profiles
      PS50025 (LAM_G_DOMAIN)
5. IPR000742
   Epidermal growth factor-like domain
   1. PF00008 (EGF)
      1,690 - 1,720
      Pfam
      PF00008 (EGF)
      1,333 - 1,359
      Pfam
      PF00008 (EGF)
      1,043 - 1,072
      Pfam
      PF00008 (EGF)
      607 - 636
      Pfam
      PF00008 (EGF)
      831 - 860
      Pfam
      PF00008 (EGF)
      734 - 762
      Pfam
      PF00008 (EGF)
   2. PS50026 (EGF_3)
      687 - 723
      PROSITE profiles
      PS50026 (EGF_3)
      2,095 - 2,125
      PROSITE profiles
      PS50026 (EGF_3)
      1,076 - 1,112
      PROSITE profiles
      PS50026 (EGF_3)
      524 - 562
      PROSITE profiles
      PS50026 (EGF_3)
      390 - 428
      PROSITE profiles
      PS50026 (EGF_3)
      1,114 - 1,155
      PROSITE profiles
      PS50026 (EGF_3)
      563 - 597
      PROSITE profiles
      PS50026 (EGF_3)
      2,011 - 2,049
      PROSITE profiles
      PS50026 (EGF_3)
      258 - 298
      PROSITE profiles
      PS50026 (EGF_3)
      766 - 803
      PROSITE profiles
      PS50026 (EGF_3)
      341 - 377
      PROSITE profiles
      PS50026 (EGF_3)
      489 - 522
      PROSITE profiles
      PS50026 (EGF_3)
      725 - 764
      PROSITE profiles
      PS50026 (EGF_3)
      1,938 - 1,972
      PROSITE profiles
      PS50026 (EGF_3)
      603 - 639
      PROSITE profiles
      PS50026 (EGF_3)
      1,039 - 1,074
      PROSITE profiles
      PS50026 (EGF_3)
      449 - 488
      PROSITE profiles
      PS50026 (EGF_3)
      2,052 - 2,093
      PROSITE profiles
      PS50026 (EGF_3)
      827 - 863
      PROSITE profiles
      PS50026 (EGF_3)
      1,974 - 2,009
      PROSITE profiles
      PS50026 (EGF_3)
      641 - 685
      PROSITE profiles
      PS50026 (EGF_3)
      932 - 968
      PROSITE profiles
      PS50026 (EGF_3)
      893 - 930
      PROSITE profiles
      PS50026 (EGF_3)
      970 - 1,037
      PROSITE profiles
      PS50026 (EGF_3)
      300 - 339
      PROSITE profiles
      PS50026 (EGF_3)
      1,686 - 1,722
      PROSITE profiles
      PS50026 (EGF_3)
      1,329 - 1,365
      PROSITE profiles
      PS50026 (EGF_3)
   3. SM00181 (EGF)
      2,014 - 2,049
      SMART
      SM00181 (EGF)
      1,079 - 1,112
      SMART
      SM00181 (EGF)
      303 - 339
      SMART
      SM00181 (EGF)
      606 - 639
      SMART
      SM00181 (EGF)
      492 - 522
      SMART
      SM00181 (EGF)
      2,111 - 2,154
      SMART
      SM00181 (EGF)
      527 - 562
      SMART
      SM00181 (EGF)
      566 - 597
      SMART
      SM00181 (EGF)
      2,055 - 2,093
      SMART
      SM00181 (EGF)
      769 - 803
      SMART
      SM00181 (EGF)
      436 - 488
      SMART
      SM00181 (EGF)
      644 - 685
      SMART
      SM00181 (EGF)
      690 - 723
      SMART
      SM00181 (EGF)
      1,689 - 1,722
      SMART
      SM00181 (EGF)
      893 - 930
      SMART
      SM00181 (EGF)
      728 - 764
      SMART
      SM00181 (EGF)
      1,042 - 1,074
      SMART
      SM00181 (EGF)
      261 - 298
      SMART
      SM00181 (EGF)
      1,117 - 1,155
      SMART
      SM00181 (EGF)
      1,332 - 1,365
      SMART
      SM00181 (EGF)
      935 - 968
      SMART
      SM00181 (EGF)
      830 - 863
      SMART
      SM00181 (EGF)
      393 - 428
      SMART
      SM00181 (EGF)
      973 - 1,037
      SMART
      SM00181 (EGF)
      344 - 377
      SMART
      SM00181 (EGF)
      1,977 - 2,009
      SMART
      SM00181 (EGF)
      1,939 - 1,972
      SMART
      SM00181 (EGF)
6. IPR001881
   EGF-like calcium-binding domain
   1. SM00179 (EGF_CA)
      1,933 - 1,972
      SMART
      SM00179 (EGF_CA)
      603 - 639
      SMART
      SM00179 (EGF_CA)
      1,039 - 1,074
      SMART
      SM00179 (EGF_CA)
      341 - 377
      SMART
      SM00179 (EGF_CA)
      865 - 930
      SMART
      SM00179 (EGF_CA)
      932 - 968
      SMART
      SM00179 (EGF_CA)
      1,686 - 1,722
      SMART
      SM00179 (EGF_CA)
      766 - 803
      SMART
      SM00179 (EGF_CA)
      524 - 562
      SMART
      SM00179 (EGF_CA)
      2,011 - 2,049
      SMART
      SM00179 (EGF_CA)
      725 - 764
      SMART
      SM00179 (EGF_CA)
      827 - 863
      SMART
      SM00179 (EGF_CA)
      1,329 - 1,365
      SMART
      SM00179 (EGF_CA)
      436 - 488
      SMART
      SM00179 (EGF_CA)
      305 - 339
      SMART
      SM00179 (EGF_CA)
      1,076 - 1,112
      SMART
      SM00179 (EGF_CA)
      1,974 - 2,009
      SMART
      SM00179 (EGF_CA)
      687 - 723
      SMART
      SM00179 (EGF_CA)
   2. PF07645 (EGF_CA)
      766 - 798
      Pfam
      PF07645 (EGF_CA)
      524 - 561
      Pfam
      PF07645 (EGF_CA)
7. IPR009030
   Insulin-like growth factor binding protein, N-terminal
   1. SSF57184 (Growth fa...)
      674 - 811
      SUPERFAMILY
      SSF57184 (Growth factor receptor domain)
8. IPR013032
   EGF-like, conserved site
   1. PS00022 (EGF_1)
      510 - 521
      PROSITE patterns
      PS00022 (EGF_1)
      365 - 376
      PROSITE patterns
      PS00022 (EGF_1)
      627 - 638
      PROSITE patterns
      PS00022 (EGF_1)
      752 - 763
      PROSITE patterns
      PS00022 (EGF_1)
      2,142 - 2,153
      PROSITE patterns
      PS00022 (EGF_1)
      1,143 - 1,154
      PROSITE patterns
      PS00022 (EGF_1)
      1,025 - 1,036
      PROSITE patterns
      PS00022 (EGF_1)
      2,037 - 2,048
      PROSITE patterns
      PS00022 (EGF_1)
      851 - 862
      PROSITE patterns
      PS00022 (EGF_1)
      327 - 338
      PROSITE patterns
      PS00022 (EGF_1)
      1,062 - 1,073
      PROSITE patterns
      PS00022 (EGF_1)
      673 - 684
      PROSITE patterns
      PS00022 (EGF_1)
      2,081 - 2,092
      PROSITE patterns
      PS00022 (EGF_1)
      711 - 722
      PROSITE patterns
      PS00022 (EGF_1)
      1,353 - 1,364
      PROSITE patterns
      PS00022 (EGF_1)
      791 - 802
      PROSITE patterns
      PS00022 (EGF_1)
      1,997 - 2,008
      PROSITE patterns
      PS00022 (EGF_1)
      1,100 - 1,111
      PROSITE patterns
      PS00022 (EGF_1)
      1,710 - 1,721
      PROSITE patterns
      PS00022 (EGF_1)
      956 - 967
      PROSITE patterns
      PS00022 (EGF_1)
      550 - 561
      PROSITE patterns
      PS00022 (EGF_1)
      476 - 487
      PROSITE patterns
      PS00022 (EGF_1)
      585 - 596
      PROSITE patterns
      PS00022 (EGF_1)
      416 - 427
      PROSITE patterns
      PS00022 (EGF_1)
   2. PS01186 (EGF_2)
      476 - 487
      PROSITE patterns
      PS01186 (EGF_2)
      1,062 - 1,073
      PROSITE patterns
      PS01186 (EGF_2)
      851 - 862
      PROSITE patterns
      PS01186 (EGF_2)
      1,997 - 2,008
      PROSITE patterns
      PS01186 (EGF_2)
      550 - 561
      PROSITE patterns
      PS01186 (EGF_2)
      416 - 427
      PROSITE patterns
      PS01186 (EGF_2)
      1,960 - 1,971
      PROSITE patterns
      PS01186 (EGF_2)
      1,143 - 1,154
      PROSITE patterns
      PS01186 (EGF_2)
      627 - 638
      PROSITE patterns
      PS01186 (EGF_2)
      286 - 297
      PROSITE patterns
      PS01186 (EGF_2)
      956 - 967
      PROSITE patterns
      PS01186 (EGF_2)
      510 - 521
      PROSITE patterns
      PS01186 (EGF_2)
      791 - 802
      PROSITE patterns
      PS01186 (EGF_2)
      711 - 722
      PROSITE patterns
      PS01186 (EGF_2)
      1,353 - 1,364
      PROSITE patterns
      PS01186 (EGF_2)
      1,025 - 1,036
      PROSITE patterns
      PS01186 (EGF_2)
      365 - 376
      PROSITE patterns
      PS01186 (EGF_2)
      1,710 - 1,721
      PROSITE patterns
      PS01186 (EGF_2)
      1,100 - 1,111
      PROSITE patterns
      PS01186 (EGF_2)
      585 - 596
      PROSITE patterns
      PS01186 (EGF_2)
      327 - 338
      PROSITE patterns
      PS01186 (EGF_2)
   3. PF12661 (hEGF)
      1,024 - 1,036
      Pfam
      PF12661 (hEGF)
      476 - 487
      Pfam
      PF12661 (hEGF)
9. IPR018097
   EGF-like calcium-binding, conserved site
   1. PS01187 (EGF_CA)
      932 - 956
      PROSITE patterns
      PS01187 (EGF_CA)
      1,974 - 1,997
      PROSITE patterns
      PS01187 (EGF_CA)
      827 - 851
      PROSITE patterns
      PS01187 (EGF_CA)
      759 - 791
      PROSITE patterns
      PS01187 (EGF_CA)
      725 - 752
      PROSITE patterns
      PS01187 (EGF_CA)
      524 - 550
      PROSITE patterns
      PS01187 (EGF_CA)
      1,076 - 1,100
      PROSITE patterns
      PS01187 (EGF_CA)
      1,032 - 1,062
      PROSITE patterns
      PS01187 (EGF_CA)
10. IPR000152
    EGF-type aspartate/asparagine hydroxylation site
    1. PS00010 (ASX_HYDROXYL)
       743 - 754
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       947 - 958
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       1,091 - 1,102
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       541 - 552
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       782 - 793
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       1,988 - 1,999
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       1,344 - 1,355
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       908 - 919
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       1,053 - 1,064
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       842 - 853
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)
       1,951 - 1,962
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)

no IPR
Unintegrated signatures

1. G3DSA:2.10.25.10
   800 - 822
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   1,338 - 1,360
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   971 - 1,037
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   2,051 - 2,093
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   900 - 929
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   823 - 866
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   725 - 799
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   644 - 723
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   290 - 337
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   338 - 378
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   1,073 - 1,113
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   2,094 - 2,155
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   1,038 - 1,072
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   930 - 970
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
2. G3DSA:2.170.3...
   1,935 - 2,050
   GENE3D
   G3DSA:2.170.300.10 (G3DSA:2.170.300.10)
   392 - 523
   GENE3D
   G3DSA:2.170.300.10 (G3DSA:2.170.300.10)
   526 - 641
   GENE3D
   G3DSA:2.170.300.10 (G3DSA:2.170.300.10)
3. PR00011 (EGFLAMININ)
   578 - 596
   PRINTS
   PR00011 (EGFLAMININ)
   1,136 - 1,154
   PRINTS
   PR00011 (EGFLAMININ)
   503 - 521
   PRINTS
   PR00011 (EGFLAMININ)
4. PTHR24043 (FAMILY N...)
   648 - 2,231
   PANTHER
   PTHR24043 (FAMILY NOT NAMED)
5. PTHR24043:SF1 (SUBF...)
   648 - 2,231
   PANTHER
   PTHR24043:SF1 (SUBFAMILY NOT NAMED)
6. SSF57196 (EGF/Laminin)
   566 - 599
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,039 - 1,081
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   307 - 345
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   932 - 975
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   899 - 937
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   2,053 - 2,099
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,939 - 1,979
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,688 - 1,728
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,970 - 2,015
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   338 - 378
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   456 - 488
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   2,010 - 2,050
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   389 - 430
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   524 - 562
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   603 - 640
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   827 - 870
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
7. TMhelix
   2,168 - 2,190
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006952 defense response

#### Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

#### Cellular Component

None predicted.