Protein

## EMLSAP00000011335

Length
1,703 amino acids

### Protein family membership

- De-etiolated protein 1, Det1 (IPR019138)

### Domains and repeats

1. Domain
   73 - 269
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   322 - 449
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   647 - 680
   - Tetratricopeptide repeat-containing domain (IPR013026)
   1,498 - 1,520
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)
   1,582 - 1,614
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)
   1,615 - 1,642
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)
   1,643 - 1,669
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)
   1,670 - 1,688
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)
2. Domain
   74 - 102
   - RNA helicase, DEAD-box type, Q motif (IPR014014)
3. Domain
   93 - 296
   - Helicase, superfamily 1/2, ATP-binding domain (IPR014001)
     - DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
   323 - 400
   - Helicase, C-terminal (IPR001650)
   572 - 686
   - Tetratricopeptide-like helical (IPR011990)
   1,497 - 1,520
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   1,537 - 1,560
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   1,581 - 1,612
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   1,613 - 1,640
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   1,641 - 1,668
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   1,669 - 1,700
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
4. Repeat
   571 - 604
   - Tetratricopeptide repeat (IPR019734)
   647 - 680
   - Tetratricopeptide repeat (IPR019734)

1 200 400 600 800 1000 1200 1400 1600 1703

### Detailed signature matches

1. IPR019138
   De-etiolated protein 1, Det1
   1. PF09737 (Det1)
      818 - 1,213
      Pfam
      PF09737 (Det1)
2. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      112 - 167
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      322 - 449
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      73 - 269
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
3. IPR014014
   RNA helicase, DEAD-box type, Q motif
   1. PS51195 (Q_MOTIF)
      74 - 102
      PROSITE profiles
      PS51195 (Q_MOTIF)
4. IPR014001
   Helicase, superfamily 1/2, ATP-binding domain
   1. SM00487 (DEXDc)
      93 - 296
      SMART
      SM00487 (DEXDc)
   2. PS51192 (HELICASE_A...)
      105 - 277
      PROSITE profiles
      PS51192 (HELICASE_ATP_BIND_1)
5. IPR011545
   DNA/RNA helicase, DEAD/DEAH box type, N-terminal
   1. PF00270 (DEAD)
      98 - 265
      Pfam
      PF00270 (DEAD)
6. IPR001650
   Helicase, C-terminal
   1. PF00271 (Helicase_C)
      333 - 400
      Pfam
      PF00271 (Helicase_C)
   2. SM00490 (HELICc)
      323 - 400
      SMART
      SM00490 (HELICc)
7. IPR011990
   Tetratricopeptide-like helical
   1. G3DSA:1.25.40.10
      572 - 686
      GENE3D
      G3DSA:1.25.40.10 (G3DSA:1.25.40.10)
8. IPR013026
   Tetratricopeptide repeat-containing domain
   1. PS50293 (TPR_REGION)
      647 - 680
      PROSITE profiles
      PS50293 (TPR_REGION)
9. IPR015880
   Zinc finger, C2H2-like
   1. SM00355 (ZnF_C2H2)
      1,613 - 1,635
      SMART
      SM00355 (ZnF_C2H2)
      1,641 - 1,663
      SMART
      SM00355 (ZnF_C2H2)
      1,669 - 1,695
      SMART
      SM00355 (ZnF_C2H2)
      1,581 - 1,603
      SMART
      SM00355 (ZnF_C2H2)
      1,497 - 1,520
      SMART
      SM00355 (ZnF_C2H2)
      1,537 - 1,559
      SMART
      SM00355 (ZnF_C2H2)
10. IPR007087
    Zinc finger, C2H2
    1. PF00096 (zf-C2H2)
       1,613 - 1,635
       Pfam
       PF00096 (zf-C2H2)
       1,498 - 1,520
       Pfam
       PF00096 (zf-C2H2)
       1,582 - 1,603
       Pfam
       PF00096 (zf-C2H2)
    2. PS50157 (ZINC_FINGE...)
       1,669 - 1,700
       PROSITE profiles
       PS50157 (ZINC_FINGER_C2H2_2)
       1,497 - 1,520
       PROSITE profiles
       PS50157 (ZINC_FINGER_C2H2_2)
       1,641 - 1,668
       PROSITE profiles
       PS50157 (ZINC_FINGER_C2H2_2)
       1,581 - 1,612
       PROSITE profiles
       PS50157 (ZINC_FINGER_C2H2_2)
       1,613 - 1,640
       PROSITE profiles
       PS50157 (ZINC_FINGER_C2H2_2)
       1,537 - 1,560
       PROSITE profiles
       PS50157 (ZINC_FINGER_C2H2_2)
    3. PS00028 (ZINC_FINGE...)
       1,499 - 1,520
       PROSITE patterns
       PS00028 (ZINC_FINGER_C2H2_1)
       1,643 - 1,663
       PROSITE patterns
       PS00028 (ZINC_FINGER_C2H2_1)
       1,583 - 1,603
       PROSITE patterns
       PS00028 (ZINC_FINGER_C2H2_1)
       1,538 - 1,559
       PROSITE patterns
       PS00028 (ZINC_FINGER_C2H2_1)
       1,615 - 1,635
       PROSITE patterns
       PS00028 (ZINC_FINGER_C2H2_1)
11. IPR013087
    Zinc finger C2H2-type/integrase DNA-binding domain
    1. G3DSA:3.30.16...
       1,670 - 1,688
       GENE3D
       G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
       1,498 - 1,520
       GENE3D
       G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
       1,582 - 1,614
       GENE3D
       G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
       1,643 - 1,669
       GENE3D
       G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
       1,615 - 1,642
       GENE3D
       G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
12. IPR019734
    Tetratricopeptide repeat
    1. SM00028 (TPR)
       571 - 604
       SMART
       SM00028 (TPR)
       647 - 680
       SMART
       SM00028 (TPR)
    2. PS50005 (TPR)
       647 - 680
       PROSITE profiles
       PS50005 (TPR)
13. IPR000629
    RNA helicase, ATP-dependent, DEAD-box, conserved site
    1. PS00039 (DEAD_ATP_H...)
       223 - 231
       PROSITE patterns
       PS00039 (DEAD_ATP_HELICASE)

no IPR
Unintegrated signatures

1. Coil
   486 - 514
   COILS
   Coil (Coil)
2. G3DSA:3.40.50...
   328 - 441
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   79 - 269
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PF13465 (zf-H2C2_2)
   1,656 - 1,679
   Pfam
   PF13465 (zf-H2C2_2)
4. PF13894 (zf-C2H2_4)
   1,537 - 1,559
   Pfam
   PF13894 (zf-C2H2_4)
5. PTHR24031 (FAMILY N...)
   79 - 1,492
   PANTHER
   PTHR24031 (FAMILY NOT NAMED)
6. PTHR24031:SF61 (SUB...)
   79 - 1,492
   PANTHER
   PTHR24031:SF61 (SUBFAMILY NOT NAMED)
7. SSF48452 (TPR-like)
   572 - 692
   SUPERFAMILY
   SSF48452 (TPR-like)
8. SSF57667 (beta-beta...)
   1,635 - 1,687
   SUPERFAMILY
   SSF57667 (beta-beta-alpha zinc fingers)
   1,593 - 1,650
   SUPERFAMILY
   SSF57667 (beta-beta-alpha zinc fingers)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0046872 metal ion binding

#### Cellular Component

None predicted.