Protein

## EMLSAP00000011927

Length
594 amino acids

### Protein family membership

- Katanin p60 subunit A1 (IPR028596)

### Domains and repeats

1. Domain
   303 - 536
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
     - AAA+ ATPase domain (IPR003593)
       - ATPase, AAA-type, core (IPR003959)
2. Repeat
   108 - 133
   - RPEL repeat (IPR004018)

1 100 200 300 400 500 594

### Detailed signature matches

1. IPR028596
   Katanin p60 subunit A1
   1. MF_03023 (Katanin_p...)
      65 - 594
      HAMAP
      MF_03023 (Katanin_p60_A1)
2. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      303 - 536
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
3. IPR003593
   AAA+ ATPase domain
   1. SM00382 (AAA)
      348 - 487
      SMART
      SM00382 (AAA)
4. IPR003959
   ATPase, AAA-type, core
   1. PF00004 (AAA)
      352 - 484
      Pfam
      PF00004 (AAA)
5. IPR004018
   RPEL repeat
   1. PS51073 (RPEL)
      108 - 133
      PROSITE profiles
      PS51073 (RPEL)
   2. PF02755 (RPEL)
      109 - 131
      Pfam
      PF02755 (RPEL)
6. IPR003960
   ATPase, AAA-type, conserved site
   1. PS00674 (AAA)
      457 - 476
      PROSITE patterns
      PS00674 (AAA)

no IPR
Unintegrated signatures

1. G3DSA:1.10.8.60
   494 - 575
   GENE3D
   G3DSA:1.10.8.60 (G3DSA:1.10.8.60)
2. G3DSA:3.40.50...
   310 - 493
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PTHR23074 (AAA ATPASE)
   163 - 594
   PANTHER
   PTHR23074 (AAA ATPASE)
4. PTHR23074:SF19 (KAT...)
   163 - 594
   PANTHER
   PTHR23074:SF19 (KATANIN-RELATED)

### GO term prediction

#### Biological Process

GO:0051013 microtubule severing

#### Molecular Function

GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0008568 microtubule-severing ATPase activity
GO:0017111 nucleoside-triphosphatase activity

#### Cellular Component

None predicted.