Protein

## EMLSAP00000003220

Length
671 amino acids

### Protein family membership

- Mannose-6-phosphate isomerase, type I (IPR001250)
  - Mannose-6-phosphate isomerase (IPR016305)

### Domains and repeats

1. Domain
   2 - 378
   - RmlC-like jelly roll fold (IPR014710)
     - RmlC-like cupin domain (IPR011051)
   511 - 670
   - Nucleic acid-binding, OB-fold (IPR012340)
     - tRNA-binding domain (IPR002547)

1 100 200 300 400 500 600 671

### Detailed signature matches

1. IPR001250
   Mannose-6-phosphate isomerase, type I
   1. PF01238 (PMI_typeI)
      2 - 345
      Pfam
      PF01238 (PMI_typeI)
   2. TIGR00218
      7 - 345
      UNKNOWN
      TIGR00218 (TIGR00218)
2. IPR016305
   Mannose-6-phosphate isomerase
   1. PR00714 (MAN6PISMRASE)
      269 - 288
      PRINTS
      PR00714 (MAN6PISMRASE)
      215 - 230
      PRINTS
      PR00714 (MAN6PISMRASE)
      3 - 21
      PRINTS
      PR00714 (MAN6PISMRASE)
      83 - 104
      PRINTS
      PR00714 (MAN6PISMRASE)
      34 - 49
      PRINTS
      PR00714 (MAN6PISMRASE)
      231 - 250
      PRINTS
      PR00714 (MAN6PISMRASE)
      118 - 141
      PRINTS
      PR00714 (MAN6PISMRASE)
      250 - 269
      PRINTS
      PR00714 (MAN6PISMRASE)
   2. PTHR10309 (MANNOSE-...)
      1 - 383
      PANTHER
      PTHR10309 (MANNOSE-6-PHOSPHATE ISOMERASE)
3. IPR014710
   RmlC-like jelly roll fold
   1. G3DSA:2.60.12...
      282 - 378
      GENE3D
      G3DSA:2.60.120.10 (G3DSA:2.60.120.10)
      5 - 132
      GENE3D
      G3DSA:2.60.120.10 (G3DSA:2.60.120.10)
      233 - 268
      GENE3D
      G3DSA:2.60.120.10 (G3DSA:2.60.120.10)
4. IPR011051
   RmlC-like cupin domain
   1. SSF51182 (RmlC-like...)
      2 - 365
      SUPERFAMILY
      SSF51182 (RmlC-like cupins)
5. IPR012340
   Nucleic acid-binding, OB-fold
   1. SSF50249 (Nucleic a...)
      511 - 661
      SUPERFAMILY
      SSF50249 (Nucleic acid-binding proteins)
   2. G3DSA:2.40.50...
      511 - 670
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
6. IPR002547
   tRNA-binding domain
   1. PF01588 (tRNA_bind)
      517 - 609
      Pfam
      PF01588 (tRNA_bind)
   2. PS50886 (TRBD)
      511 - 612
      PROSITE profiles
      PS50886 (TRBD)
7. IPR018050
   Phosphomannose isomerase, type I, conserved site
   1. PS00965 (PMI_I_1)
      118 - 126
      PROSITE patterns
      PS00965 (PMI_I_1)
   2. PS00966 (PMI_I_2)
      250 - 275
      PROSITE patterns
      PS00966 (PMI_I_2)

no IPR
Unintegrated signatures

1. Coil
   414 - 435
   COILS
   Coil (Coil)
   379 - 400
   COILS
   Coil (Coil)
2. G3DSA:1.10.44...
   133 - 226
   GENE3D
   G3DSA:1.10.441.10 (G3DSA:1.10.441.10)
   269 - 281
   GENE3D
   G3DSA:1.10.441.10 (G3DSA:1.10.441.10)

### GO term prediction

#### Biological Process

GO:0005975 carbohydrate metabolic process
GO:0009298 GDP-mannose biosynthetic process

#### Molecular Function

GO:0000049 tRNA binding
GO:0004476 mannose-6-phosphate isomerase activity
GO:0008270 zinc ion binding

#### Cellular Component

None predicted.