Protein

## EMLSAP00000011843

Length
750 amino acids

### Protein family membership

- Cleavage and polyadenylation specificity factor subunit 2 (IPR027075)

### Domains and repeats

1. Domain
   9 - 193
   - Beta-lactamase-like (IPR001279)
   243 - 368
   - Beta-Casp domain (IPR022712)
   526 - 564
   - RNA-metabolising metallo-beta-lactamase (IPR011108)
   607 - 747
   - Cleavage and polyadenylation specificity factor 2, C-terminal (IPR025069)

1 100 200 300 400 500 600 700 750

### Detailed signature matches

1. IPR027075
   Cleavage and polyadenylation specificity factor subunit 2
   1. PTHR11203:SF5 (CLEA...)
      2 - 750
      PANTHER
      PTHR11203:SF5 (CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR, 100 KDA SUBUNIT)
2. IPR001279
   Beta-lactamase-like
   1. G3DSA:3.60.15.10
      9 - 193
      GENE3D
      G3DSA:3.60.15.10 (G3DSA:3.60.15.10)
   2. PF00753 (Lactamase_B)
      18 - 74
      Pfam
      PF00753 (Lactamase_B)
3. IPR022712
   Beta-Casp domain
   1. SM01027 (Beta-Casp)
      243 - 368
      SMART
      SM01027 (Beta-Casp)
   2. PF10996 (Beta-Casp)
      243 - 367
      Pfam
      PF10996 (Beta-Casp)
4. IPR011108
   RNA-metabolising metallo-beta-lactamase
   1. PF07521 (RMMBL)
      526 - 564
      Pfam
      PF07521 (RMMBL)
5. IPR025069
   Cleavage and polyadenylation specificity factor 2, C-terminal
   1. PF13299 (CPSF100_C)
      607 - 747
      Pfam
      PF13299 (CPSF100_C)

no IPR
Unintegrated signatures

1. PTHR11203 (CLEAVAGE...)
   2 - 750
   PANTHER
   PTHR11203 (CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR)
2. SSF56281 (Metallo-h...)
   458 - 598
   SUPERFAMILY
   SSF56281 (Metallo-hydrolase/oxidoreductase)
   4 - 378
   SUPERFAMILY
   SSF56281 (Metallo-hydrolase/oxidoreductase)

### GO term prediction

#### Biological Process

GO:0006378 mRNA polyadenylation
GO:0006379 mRNA cleavage

#### Molecular Function

GO:0016787 hydrolase activity

#### Cellular Component

GO:0005847 mRNA cleavage and polyadenylation specificity factor complex