Protein

## EMLSAP00000000118

Length
895 amino acids

### Protein family membership

- Aconitase/isopropylmalate dehydratase (IPR015937)
  - Aconitase/Iron regulatory protein 2/2-methylisocitrate dehydratase (IPR015934)
    - Aconitase/iron regulatory protein 2 (IPR006249)

### Domains and repeats

1. Domain
   8 - 629
   - Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha (IPR001030)
   633 - 892
   - Aconitase/3-isopropylmalate dehydratase, swivel (IPR015928)
     - Aconitase A/isopropylmalate dehydratase small subunit, swivel (IPR000573)
2. Domain
   26 - 241
   - Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (IPR015931)
   243 - 362
   - Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 (IPR015932)
   364 - 388
   - Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (IPR015931)
   421 - 576
   - Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (IPR015931)

1 100 200 300 400 500 600 700 800 895

### Detailed signature matches

1. IPR015937
   Aconitase/isopropylmalate dehydratase
   1. PTHR11670 (ACONITASE)
      1 - 895
      PANTHER
      PTHR11670 (ACONITASE)
2. IPR015934
   Aconitase/Iron regulatory protein 2/2-methylisocitrate dehydratase
   1. PTHR11670:SF1 (ACON...)
      1 - 895
      PANTHER
      PTHR11670:SF1 (ACONITASE)
3. IPR006249
   Aconitase/iron regulatory protein 2
   1. TIGR01341
      17 - 893
      UNKNOWN
      TIGR01341 (TIGR01341)
4. IPR001030
   Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha
   1. PR00415 (ACONITASE)
      495 - 508
      PRINTS
      PR00415 (ACONITASE)
      142 - 155
      PRINTS
      PR00415 (ACONITASE)
      271 - 284
      PRINTS
      PR00415 (ACONITASE)
      209 - 224
      PRINTS
      PR00415 (ACONITASE)
      195 - 208
      PRINTS
      PR00415 (ACONITASE)
      285 - 298
      PRINTS
      PR00415 (ACONITASE)
      166 - 174
      PRINTS
      PR00415 (ACONITASE)
      367 - 381
      PRINTS
      PR00415 (ACONITASE)
      433 - 444
      PRINTS
      PR00415 (ACONITASE)
   2. PF00330 (Aconitase)
      54 - 564
      Pfam
      PF00330 (Aconitase)
   3. SSF53732 (Aconitase...)
      8 - 629
      SUPERFAMILY
      SSF53732 (Aconitase iron-sulfur domain)
5. IPR015931
   Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
   1. G3DSA:3.30.49...
      26 - 241
      GENE3D
      G3DSA:3.30.499.10 (G3DSA:3.30.499.10)
      421 - 576
      GENE3D
      G3DSA:3.30.499.10 (G3DSA:3.30.499.10)
      364 - 388
      GENE3D
      G3DSA:3.30.499.10 (G3DSA:3.30.499.10)
6. IPR015932
   Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2
   1. G3DSA:3.40.10...
      243 - 362
      GENE3D
      G3DSA:3.40.1060.10 (G3DSA:3.40.1060.10)
7. IPR015928
   Aconitase/3-isopropylmalate dehydratase, swivel
   1. G3DSA:3.20.19.10
      639 - 892
      GENE3D
      G3DSA:3.20.19.10 (G3DSA:3.20.19.10)
   2. SSF52016 (LeuD/IlvD...)
      633 - 892
      SUPERFAMILY
      SSF52016 (LeuD/IlvD-like)
8. IPR000573
   Aconitase A/isopropylmalate dehydratase small subunit, swivel
   1. PF00694 (Aconitase_C)
      693 - 821
      Pfam
      PF00694 (Aconitase_C)
9. IPR018136
   Aconitase family, 4Fe-4S cluster binding site
   1. PS00450 (ACONITASE_1)
      429 - 445
      PROSITE patterns
      PS00450 (ACONITASE_1)

### GO term prediction

#### Biological Process

GO:0008152 metabolic process

#### Molecular Function

GO:0051539 4 iron, 4 sulfur cluster binding

#### Cellular Component

None predicted.