Protein

## EMLSAP00000009349

Length
2,130 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   461 - 844
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
     - AAA+ ATPase domain (IPR003593)
   1,169 - 1,466
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
     - AAA+ ATPase domain (IPR003593)
   1,473 - 1,683
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   2,000 - 2,104
   - Immunoglobulin E-set (IPR014756)
2. Domain
   462 - 645
   - Helicase, superfamily 1/2, ATP-binding domain (IPR014001)
     - DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
   663 - 877
   - Helicase, C-terminal (IPR001650)
   934 - 1,248
   - Sec63 domain (IPR004179)
   1,283 - 1,487
   - Helicase, superfamily 1/2, ATP-binding domain (IPR014001)
     - DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
   1,507 - 1,713
   - Helicase, C-terminal (IPR001650)
   1,771 - 2,104
   - Sec63 domain (IPR004179)

1 200 400 600 800 1000 1200 1400 1600 1800 2000 2130

### Detailed signature matches

1. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      1,169 - 1,464
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      631 - 844
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      1,473 - 1,683
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      461 - 621
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
2. IPR014001
   Helicase, superfamily 1/2, ATP-binding domain
   1. SM00487 (DEXDc)
      1,283 - 1,487
      SMART
      SM00487 (DEXDc)
      462 - 645
      SMART
      SM00487 (DEXDc)
   2. PS51192 (HELICASE_A...)
      475 - 628
      PROSITE profiles
      PS51192 (HELICASE_ATP_BIND_1)
      1,296 - 1,471
      PROSITE profiles
      PS51192 (HELICASE_ATP_BIND_1)
3. IPR011545
   DNA/RNA helicase, DEAD/DEAH box type, N-terminal
   1. PF00270 (DEAD)
      468 - 612
      Pfam
      PF00270 (DEAD)
      1,289 - 1,454
      Pfam
      PF00270 (DEAD)
4. IPR003593
   AAA+ ATPase domain
   1. SM00382 (AAA)
      480 - 674
      SMART
      SM00382 (AAA)
      1,301 - 1,466
      SMART
      SM00382 (AAA)
5. IPR001650
   Helicase, C-terminal
   1. PF00271 (Helicase_C)
      738 - 815
      Pfam
      PF00271 (Helicase_C)
      1,577 - 1,654
      Pfam
      PF00271 (Helicase_C)
   2. SM00490 (HELICc)
      728 - 816
      SMART
      SM00490 (HELICc)
      1,565 - 1,655
      SMART
      SM00490 (HELICc)
   3. PS51194 (HELICASE_CTER)
      663 - 877
      PROSITE profiles
      PS51194 (HELICASE_CTER)
      1,507 - 1,713
      PROSITE profiles
      PS51194 (HELICASE_CTER)
6. IPR004179
   Sec63 domain
   1. PF02889 (Sec63)
      937 - 1,247
      Pfam
      PF02889 (Sec63)
      1,777 - 2,103
      Pfam
      PF02889 (Sec63)
   2. SM00973 (Sec63)
      1,774 - 2,103
      SMART
      SM00973 (Sec63)
      937 - 1,247
      SMART
      SM00973 (Sec63)
   3. SM00611 (SEC63)
      934 - 1,248
      SMART
      SM00611 (SEC63)
      1,771 - 2,104
      SMART
      SM00611 (SEC63)
7. IPR014756
   Immunoglobulin E-set
   1. SSF81296 (E set dom...)
      2,000 - 2,104
      SUPERFAMILY
      SSF81296 (E set domains)

no IPR
Unintegrated signatures

1. G3DSA:1.10.33...
   1,802 - 1,918
   GENE3D
   G3DSA:1.10.3380.10 (G3DSA:1.10.3380.10)
   965 - 1,082
   GENE3D
   G3DSA:1.10.3380.10 (G3DSA:1.10.3380.10)
2. G3DSA:2.60.40...
   2,035 - 2,109
   GENE3D
   G3DSA:2.60.40.150 (G3DSA:2.60.40.150)
3. G3DSA:3.40.50...
   523 - 609
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   1,284 - 1,485
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   461 - 511
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   1,511 - 1,676
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   656 - 851
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
4. PTHR11752 (HELICASE...)
   84 - 1,973
   PANTHER
   PTHR11752 (HELICASE SKI2W)
5. PTHR11752:SF8 (ACTI...)
   84 - 1,973
   PANTHER
   PTHR11752:SF8 (ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3, HELC1)
6. SSF158702 (Sec63 N-...)
   1,802 - 1,985
   SUPERFAMILY
   SSF158702 (Sec63 N-terminal domain-like)
   965 - 1,140
   SUPERFAMILY
   SSF158702 (Sec63 N-terminal domain-like)
7. SSF46785 ("Winged h...)
   1,683 - 1,786
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)
   844 - 949
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0017111 nucleoside-triphosphatase activity

#### Cellular Component

None predicted.