Protein

## EMLSAP00000000297

Length
1,385 amino acids

### Protein family membership

- Translation initiation factor IF- 2 (IPR015760)
  - Translation initiation factor aIF-2, bacterial-like (IPR000178)

### Domains and repeats

1. Domain
   128 - 315
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
2. Domain
   144 - 306
   - Elongation factor, GTP-binding domain (IPR000795)
3. Domain
   145 - 300
   - Small GTP-binding protein domain (IPR005225)
   318 - 398
   - Translation protein, beta-barrel domain (IPR009000)
   456 - 575
   - Translation initiation factor IF- 2, domain 3 (IPR023115)
   576 - 663
   - Translation protein, beta-barrel domain (IPR009000)

1 200 400 600 800 1000 1200 1385

### Detailed signature matches

1. IPR015760
   Translation initiation factor IF- 2
   1. PTHR23115:SF41 (TRA...)
      122 - 648
      PANTHER
      PTHR23115:SF41 (TRANSLATION INITIATION FACTOR IF-2)
2. IPR000178
   Translation initiation factor aIF-2, bacterial-like
   1. PS01176 (IF2)
      627 - 649
      PROSITE patterns
      PS01176 (IF2)
   2. TIGR00487
      48 - 653
      UNKNOWN
      TIGR00487 (TIGR00487)
3. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      128 - 315
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
4. IPR000795
   Elongation factor, GTP-binding domain
   1. PF00009 (GTP_EFTU)
      144 - 306
      Pfam
      PF00009 (GTP_EFTU)
   2. PR00315 (ELONGATNFCT)
      212 - 223
      PRINTS
      PR00315 (ELONGATNFCT)
      248 - 257
      PRINTS
      PR00315 (ELONGATNFCT)
      145 - 158
      PRINTS
      PR00315 (ELONGATNFCT)
5. IPR005225
   Small GTP-binding protein domain
   1. TIGR00231
      145 - 300
      UNKNOWN
      TIGR00231 (TIGR00231)
6. IPR009000
   Translation protein, beta-barrel domain
   1. SSF50447 (Translati...)
      576 - 663
      SUPERFAMILY
      SSF50447 (Translation proteins)
      318 - 398
      SUPERFAMILY
      SSF50447 (Translation proteins)
7. IPR023115
   Translation initiation factor IF- 2, domain 3
   1. SSF52156 (Initiatio...)
      456 - 575
      SUPERFAMILY
      SSF52156 (Initiation factor IF2/eIF5b, domain 3)
   2. PF11987 (IF-2)
      467 - 562
      Pfam
      PF11987 (IF-2)
   3. G3DSA:3.40.50...
      474 - 542
      GENE3D
      G3DSA:3.40.50.10050 (G3DSA:3.40.50.10050)

no IPR
Unintegrated signatures

1. Coil
   1,059 - 1,080
   COILS
   Coil (Coil)
   878 - 899
   COILS
   Coil (Coil)
2. G3DSA:2.40.30.10
   574 - 663
   GENE3D
   G3DSA:2.40.30.10 (G3DSA:2.40.30.10)
3. G3DSA:3.40.50...
   142 - 383
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
4. PTHR23115 (TRANSLAT...)
   122 - 648
   PANTHER
   PTHR23115 (TRANSLATION FACTOR)

### GO term prediction

#### Biological Process

GO:0006413 translational initiation

#### Molecular Function

GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding

#### Cellular Component

GO:0005622 intracellular