Protein

## EMLSAP00000005123

Length
1,077 amino acids

### Protein family membership

- Exostosin-like (IPR004263)
  - Exostosin 3/Exostosin-like 3 (IPR027674)

### Domains and repeats

1. Domain
   567 - 748
   - EXTL2, alpha-1,4-N-acetylhexosaminyltransferase (IPR015338)
   792 - 938
   - Peptidase, metallopeptidase (IPR006026)
     - Peptidase M12A, astacin (IPR001506)
   949 - 962
   - Peptidase M12A, astacin (IPR001506)
2. Domain
   794 - 923
   - Metallopeptidase, catalytic domain (IPR024079)
   924 - 964
   - Metallopeptidase, catalytic domain (IPR024079)

1 100 200 300 400 500 600 700 800 900 1000 1077

### Detailed signature matches

1. IPR004263
   Exostosin-like
   1. PTHR11062 (EXOSTOSI...)
      17 - 756
      PANTHER
      PTHR11062 (EXOSTOSIN (HEPARAN SULFATE GLYCOSYLTRANSFERASE)-RELATED)
   2. PF03016 (Exostosin)
      209 - 408
      Pfam
      PF03016 (Exostosin)
2. IPR027674
   Exostosin 3/Exostosin-like 3
   1. PTHR11062:SF5 (EXOS...)
      17 - 756
      PANTHER
      PTHR11062:SF5 (EXOSTOSIN-LIKE 3)
3. IPR015338
   EXTL2, alpha-1,4-N-acetylhexosaminyltransferase
   1. PF09258 (Glyco_tran...)
      567 - 748
      Pfam
      PF09258 (Glyco_transf_64)
4. IPR006026
   Peptidase, metallopeptidase
   1. SM00235 (ZnMc)
      792 - 938
      SMART
      SM00235 (ZnMc)
5. IPR024079
   Metallopeptidase, catalytic domain
   1. G3DSA:3.40.39...
      924 - 964
      GENE3D
      G3DSA:3.40.390.10 (G3DSA:3.40.390.10)
      794 - 923
      GENE3D
      G3DSA:3.40.390.10 (G3DSA:3.40.390.10)
6. IPR001506
   Peptidase M12A, astacin
   1. PR00480 (ASTACIN)
      895 - 912
      PRINTS
      PR00480 (ASTACIN)
      949 - 962
      PRINTS
      PR00480 (ASTACIN)
      876 - 894
      PRINTS
      PR00480 (ASTACIN)
   2. PF01400 (Astacin)
      795 - 924
      Pfam
      PF01400 (Astacin)

no IPR
Unintegrated signatures

1. Coil
   78 - 134
   COILS
   Coil (Coil)
2. G3DSA:3.90.55...
   564 - 752
   GENE3D
   G3DSA:3.90.550.10 (G3DSA:3.90.550.10)
3. SSF53448 (Nucleotid...)
   566 - 746
   SUPERFAMILY
   SSF53448 (Nucleotide-diphospho-sugar transferases)
4. SSF55486 (Metallopr...)
   791 - 963
   SUPERFAMILY
   SSF55486 (Metalloproteases ("zincins"), catalytic domain)
5. TMhelix
   27 - 49
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis
GO:0015012 heparan sulfate proteoglycan biosynthetic process

#### Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016758 transferase activity, transferring hexosyl groups

#### Cellular Component

GO:0016021 integral component of membrane
GO:0031227 intrinsic component of endoplasmic reticulum membrane