Protein

## EMLSAP00000001589

Length
500 amino acids

### Protein family membership

- N-acetylglucosamine-6-sulfatase (IPR012251)
  - N-acetylglucosamine-6-sulfatase, eukaryotic (IPR015981)

### Domains and repeats

1. Domain
   25 - 492
   - Alkaline-phosphatase-like, core domain (IPR017850)
     - Sulfatase (IPR000917)
2. Domain
   27 - 251
   - Alkaline phosphatase-like, alpha/beta/alpha (IPR017849)
   289 - 408
   - Alkaline phosphatase-like, alpha/beta/alpha (IPR017849)
   452 - 484
   - Alkaline phosphatase-like, alpha/beta/alpha (IPR017849)

1 50 100 150 200 250 300 350 400 450 500 500

### Detailed signature matches

1. IPR012251
   N-acetylglucosamine-6-sulfatase
   1. PIRSF036666 (G6S)
      1 - 500
      PIRSF
      PIRSF036666 (G6S)
2. IPR015981
   N-acetylglucosamine-6-sulfatase, eukaryotic
   1. PTHR10342:SF5 (N-AC...)
      10 - 496
      PANTHER
      PTHR10342:SF5 (N-ACETYLGLUCOSAMINE-6-SULFATASE)
3. IPR017850
   Alkaline-phosphatase-like, core domain
   1. SSF53649 (Alkaline ...)
      288 - 492
      SUPERFAMILY
      SSF53649 (Alkaline phosphatase-like)
      25 - 256
      SUPERFAMILY
      SSF53649 (Alkaline phosphatase-like)
4. IPR000917
   Sulfatase
   1. PF00884 (Sulfatase)
      27 - 211
      Pfam
      PF00884 (Sulfatase)
      230 - 383
      Pfam
      PF00884 (Sulfatase)
5. IPR017849
   Alkaline phosphatase-like, alpha/beta/alpha
   1. G3DSA:3.40.72...
      452 - 484
      GENE3D
      G3DSA:3.40.720.10 (G3DSA:3.40.720.10)
      289 - 408
      GENE3D
      G3DSA:3.40.720.10 (G3DSA:3.40.720.10)
      27 - 251
      GENE3D
      G3DSA:3.40.720.10 (G3DSA:3.40.720.10)
6. IPR024607
   Sulfatase, conserved site
   1. PS00523 (SULFATASE_1)
      69 - 81
      PROSITE patterns
      PS00523 (SULFATASE_1)

no IPR
Unintegrated signatures

1. PTHR10342 (ARYLSULF...)
   10 - 496
   PANTHER
   PTHR10342 (ARYLSULFATASE)
2. SignalP-TM
   1 - 24
   SignalP Gram+ prok
   SignalP-TM (SignalP-TM)
3. SignalP-noTM
   1 - 24
   SignalP euk
   SignalP-noTM (SignalP-noTM)
   1 - 24
   SignalP euk
   SignalP-noTM (SignalP-noTM)

### GO term prediction

#### Biological Process

GO:0008152 metabolic process
GO:0030203 glycosaminoglycan metabolic process

#### Molecular Function

GO:0003824 catalytic activity
GO:0008449 N-acetylglucosamine-6-sulfatase activity
GO:0008484 sulfuric ester hydrolase activity

#### Cellular Component

GO:0005764 lysosome