Protein

## EMLSAP00000005593

Length
438 amino acids

### Protein family membership

- Mevalonate/galactokinase (IPR006206)
  - Galactokinase (IPR000705)

### Domains and repeats

1. Domain
   3 - 212
   - Ribosomal protein S5 domain 2-type fold (IPR020568)
     - Ribosomal protein S5 domain 2-type fold, subgroup (IPR014721)
   336 - 409
   - GHMP kinase, C-terminal domain (IPR013750)
2. Domain
   10 - 59
   - Galactokinase galactose-binding domain (IPR019539)
   122 - 183
   - GHMP kinase N-terminal domain (IPR006204)

1 50 100 150 200 250 300 350 400 438

### Detailed signature matches

1. IPR006206
   Mevalonate/galactokinase
   1. PR00959 (MEVGALKINASE)
      26 - 50
      PRINTS
      PR00959 (MEVGALKINASE)
      167 - 186
      PRINTS
      PR00959 (MEVGALKINASE)
      125 - 147
      PRINTS
      PR00959 (MEVGALKINASE)
      376 - 393
      PRINTS
      PR00959 (MEVGALKINASE)
2. IPR000705
   Galactokinase
   1. TIGR00131
      7 - 420
      UNKNOWN
      TIGR00131 (TIGR00131)
   2. PR00473 (GALCTOKINASE)
      118 - 136
      PRINTS
      PR00473 (GALCTOKINASE)
      310 - 324
      PRINTS
      PR00473 (GALCTOKINASE)
      96 - 107
      PRINTS
      PR00473 (GALCTOKINASE)
      28 - 46
      PRINTS
      PR00473 (GALCTOKINASE)
   3. PIRSF000530 (Galact...)
      2 - 438
      PIRSF
      PIRSF000530 (Galactokinase)
3. IPR020568
   Ribosomal protein S5 domain 2-type fold
   1. SSF54211 (Ribosomal...)
      3 - 206
      SUPERFAMILY
      SSF54211 (Ribosomal protein S5 domain 2-like)
4. IPR014721
   Ribosomal protein S5 domain 2-type fold, subgroup
   1. G3DSA:3.30.23...
      6 - 212
      GENE3D
      G3DSA:3.30.230.10 (G3DSA:3.30.230.10)
5. IPR019539
   Galactokinase galactose-binding domain
   1. PF10509 (GalKase_ga...)
      10 - 59
      Pfam
      PF10509 (GalKase_gal_bdg)
6. IPR006204
   GHMP kinase N-terminal domain
   1. PF00288 (GHMP_kinas...)
      122 - 183
      Pfam
      PF00288 (GHMP_kinases_N)
7. IPR013750
   GHMP kinase, C-terminal domain
   1. PF08544 (GHMP_kinas...)
      336 - 409
      Pfam
      PF08544 (GHMP_kinases_C)
8. IPR019741
   Galactokinase, conserved site
   1. PS00106 (GALACTOKINASE)
      28 - 39
      PROSITE patterns
      PS00106 (GALACTOKINASE)
9. IPR006203
   GHMP kinase, ATP-binding, conserved site
   1. PS00627 (GHMP_KINAS...)
      127 - 138
      PROSITE patterns
      PS00627 (GHMP_KINASES_ATP)

no IPR
Unintegrated signatures

1. G3DSA:3.30.70...
   308 - 433
   GENE3D
   G3DSA:3.30.70.890 (G3DSA:3.30.70.890)
   213 - 270
   GENE3D
   G3DSA:3.30.70.890 (G3DSA:3.30.70.890)
2. PTHR10457 (MEVALONA...)
   4 - 433
   PANTHER
   PTHR10457 (MEVALONATE KINASE/GALACTOKINASE)
3. PTHR10457:SF7 (GALA...)
   4 - 433
   PANTHER
   PTHR10457:SF7 (GALACTOKINASE 2)
4. SSF55060 (GHMP Kina...)
   290 - 432
   SUPERFAMILY
   SSF55060 (GHMP Kinase, C-terminal domain)
   210 - 253
   SUPERFAMILY
   SSF55060 (GHMP Kinase, C-terminal domain)

### GO term prediction

#### Biological Process

GO:0006012 galactose metabolic process
GO:0008152 metabolic process
GO:0046835 carbohydrate phosphorylation

#### Molecular Function

GO:0004335 galactokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor

#### Cellular Component

GO:0005737 cytoplasm