Protein

## EMLSAP00000004091

Length
516 amino acids

### Protein family membership

- Neurotransmitter-gated ion-channel (IPR006201)
  - Gamma-aminobutyric acid A receptor (IPR006028)

### Domains and repeats

1. Domain
   71 - 281
   - Neurotransmitter-gated ion-channel ligand-binding (IPR006202)
   283 - 410
   - Neurotransmitter-gated ion-channel transmembrane domain (IPR006029)
   443 - 514
   - Neurotransmitter-gated ion-channel transmembrane domain (IPR006029)

1 50 100 150 200 250 300 350 400 450 516

### Detailed signature matches

1. IPR006201
   Neurotransmitter-gated ion-channel
   1. PTHR18945 (NEUROTRA...)
      72 - 514
      PANTHER
      PTHR18945 (NEUROTRANSMITTER GATED ION CHANNEL)
   2. PR00252 (NRIONCHANNEL)
      195 - 209
      PRINTS
      PR00252 (NRIONCHANNEL)
      149 - 160
      PRINTS
      PR00252 (NRIONCHANNEL)
      116 - 132
      PRINTS
      PR00252 (NRIONCHANNEL)
      276 - 288
      PRINTS
      PR00252 (NRIONCHANNEL)
2. IPR006028
   Gamma-aminobutyric acid A receptor
   1. PR00253 (GABAARECEPTR)
      491 - 511
      PRINTS
      PR00253 (GABAARECEPTR)
      285 - 305
      PRINTS
      PR00253 (GABAARECEPTR)
      348 - 369
      PRINTS
      PR00253 (GABAARECEPTR)
3. IPR006202
   Neurotransmitter-gated ion-channel ligand-binding
   1. PF02931 (Neur_chan_LBD)
      71 - 281
      Pfam
      PF02931 (Neur_chan_LBD)
   2. SSF63712 (Nicotinic...)
      72 - 254
      SUPERFAMILY
      SSF63712 (Nicotinic receptor ligand binding domain-like)
   3. G3DSA:2.70.17...
      83 - 280
      GENE3D
      G3DSA:2.70.170.10 (G3DSA:2.70.170.10)
4. IPR006029
   Neurotransmitter-gated ion-channel transmembrane domain
   1. SSF90112 (Neurotran...)
      443 - 514
      SUPERFAMILY
      SSF90112 (Neurotransmitter-gated ion-channel transmembrane pore)
      283 - 410
      SUPERFAMILY
      SSF90112 (Neurotransmitter-gated ion-channel transmembrane pore)
   2. PF02932 (Neur_chan_...)
      289 - 372
      Pfam
      PF02932 (Neur_chan_memb)
5. IPR018000
   Neurotransmitter-gated ion-channel, conserved site
   1. PS00236 (NEUROTR_IO...)
      195 - 209
      PROSITE patterns
      PS00236 (NEUROTR_ION_CHANNEL)

no IPR
Unintegrated signatures

1. G3DSA:1.20.58...
   488 - 513
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
   283 - 396
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
2. SignalP-TM
   1 - 21
   SignalP Gram+ prok
   SignalP-TM (SignalP-TM)
3. SignalP-noTM
   1 - 21
   SignalP euk
   SignalP-noTM (SignalP-noTM)
   1 - 21
   SignalP euk
   SignalP-noTM (SignalP-noTM)
4. TMhelix
   496 - 515
   TMHMM
   TMhelix (TMhelix)
   350 - 372
   TMHMM
   TMhelix (TMhelix)
   318 - 335
   TMHMM
   TMhelix (TMhelix)
   284 - 306
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006810 transport
GO:0006811 ion transport

#### Molecular Function

GO:0005230 extracellular ligand-gated ion channel activity

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane