Protein

## EMLSAP00000002590

Length
913 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   252 - 347
   - Rad4/PNGase transglutaminase-like fold (IPR018325)
   357 - 410
   - Rad4 beta-hairpin domain 1 (IPR018326)
   454 - 488
   - Rad4 beta-hairpin domain 3 (IPR018328)
   532 - 620
   - Proteinase inhibitor, propeptide (IPR009020)
     - Proteinase inhibitor, carboxypeptidase propeptide (IPR003146)
   637 - 898
   - Peptidase M14, carboxypeptidase A (IPR000834)

1 100 200 300 400 500 600 700 800 913

### Detailed signature matches

1. IPR018325
   Rad4/PNGase transglutaminase-like fold
   1. PF03835 (Rad4)
      252 - 347
      Pfam
      PF03835 (Rad4)
2. IPR018326
   Rad4 beta-hairpin domain 1
   1. SM01030 (BHD_1)
      357 - 410
      SMART
      SM01030 (BHD_1)
   2. PF10403 (BHD_1)
      359 - 410
      Pfam
      PF10403 (BHD_1)
3. IPR018328
   Rad4 beta-hairpin domain 3
   1. PF10405 (BHD_3)
      454 - 488
      Pfam
      PF10405 (BHD_3)
4. IPR009020
   Proteinase inhibitor, propeptide
   1. SSF54897 (Protease ...)
      532 - 610
      SUPERFAMILY
      SSF54897 (Protease propeptides/inhibitors)
5. IPR003146
   Proteinase inhibitor, carboxypeptidase propeptide
   1. PF02244 (Propep_M14)
      547 - 609
      Pfam
      PF02244 (Propep_M14)
   2. G3DSA:3.30.70...
      533 - 620
      GENE3D
      G3DSA:3.30.70.340 (G3DSA:3.30.70.340)
6. IPR000834
   Peptidase M14, carboxypeptidase A
   1. PR00765 (CRBOXYPTASEA)
      684 - 698
      PRINTS
      PR00765 (CRBOXYPTASEA)
      760 - 768
      PRINTS
      PR00765 (CRBOXYPTASEA)
      814 - 827
      PRINTS
      PR00765 (CRBOXYPTASEA)
      662 - 674
      PRINTS
      PR00765 (CRBOXYPTASEA)
   2. PF00246 (Peptidase_M14)
      645 - 898
      Pfam
      PF00246 (Peptidase_M14)
   3. SM00631 (Zn_pept)
      637 - 895
      SMART
      SM00631 (Zn_pept)
   4. PS00132 (CARBOXYPEP...)
      684 - 706
      PROSITE patterns
      PS00132 (CARBOXYPEPT_ZN_1)

no IPR
Unintegrated signatures

1. G3DSA:3.40.63...
   630 - 909
   GENE3D
   G3DSA:3.40.630.10 (G3DSA:3.40.630.10)
2. PTHR11705 (PROTEASE...)
   478 - 909
   PANTHER
   PTHR11705 (PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B)
3. SSF53187 (Zn-depend...)
   632 - 908
   SUPERFAMILY
   SSF53187 (Zn-dependent exopeptidases)
4. SSF54001 (Cysteine ...)
   230 - 372
   SUPERFAMILY
   SSF54001 (Cysteine proteinases)

### GO term prediction

#### Biological Process

GO:0006289 nucleotide-excision repair
GO:0006508 proteolysis

#### Molecular Function

GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0008270 zinc ion binding

#### Cellular Component

GO:0005634 nucleus