Protein

## EMLSAP00000007224

Length
544 amino acids

### Protein family membership

- Dual specificity phosphatase (IPR024950)
  - Mitogen-activated protein (MAP) kinase phosphatase (IPR008343)

### Domains and repeats

1. Domain
   147 - 285
   - Rhodanese-like domain (IPR001763)
   315 - 456
   - Protein-tyrosine/Dual specificity phosphatase (IPR000387)
     - Dual specificity phosphatase, subgroup, catalytic domain (IPR020422)
2. Domain
   324 - 453
   - Dual specificity phosphatase, catalytic domain (IPR000340)

1 50 100 150 200 250 300 350 400 450 500 544

### Detailed signature matches

1. IPR024950
   Dual specificity phosphatase
   1. PTHR10159 (DUAL SPE...)
      138 - 455
      PANTHER
      PTHR10159 (DUAL SPECIFICITY PROTEIN PHOSPHATASE)
2. IPR008343
   Mitogen-activated protein (MAP) kinase phosphatase
   1. PR01764 (MAPKPHPHTASE)
      342 - 352
      PRINTS
      PR01764 (MAPKPHPHTASE)
      379 - 391
      PRINTS
      PR01764 (MAPKPHPHTASE)
      172 - 182
      PRINTS
      PR01764 (MAPKPHPHTASE)
3. IPR001763
   Rhodanese-like domain
   1. SM00450 (RHOD)
      157 - 281
      SMART
      SM00450 (RHOD)
   2. PF00581 (Rhodanese)
      160 - 249
      Pfam
      PF00581 (Rhodanese)
   3. PS50206 (RHODANESE_3)
      167 - 284
      PROSITE profiles
      PS50206 (RHODANESE_3)
   4. G3DSA:3.40.25...
      152 - 285
      GENE3D
      G3DSA:3.40.250.10 (G3DSA:3.40.250.10)
   5. SSF52821 (Rhodanese...)
      147 - 285
      SUPERFAMILY
      SSF52821 (Rhodanese/Cell cycle control phosphatase)
4. IPR020422
   Dual specificity phosphatase, subgroup, catalytic domain
   1. PS50054 (TYR_PHOSPH...)
      315 - 456
      PROSITE profiles
      PS50054 (TYR_PHOSPHATASE_DUAL)
   2. SM00195 (DSPc)
      315 - 454
      SMART
      SM00195 (DSPc)
5. IPR000340
   Dual specificity phosphatase, catalytic domain
   1. PF00782 (DSPc)
      324 - 453
      Pfam
      PF00782 (DSPc)
6. IPR000387
   Protein-tyrosine/Dual specificity phosphatase
   1. PS50056 (TYR_PHOSPH...)
      377 - 435
      PROSITE profiles
      PS50056 (TYR_PHOSPHATASE_2)
7. IPR016130
   Protein-tyrosine phosphatase, active site
   1. PS00383 (TYR_PHOSPH...)
      399 - 409
      PROSITE patterns
      PS00383 (TYR_PHOSPHATASE_1)

no IPR
Unintegrated signatures

1. G3DSA:3.90.19...
   317 - 465
   GENE3D
   G3DSA:3.90.190.10 (G3DSA:3.90.190.10)
2. PTHR10159:SF123 (DU...)
   138 - 455
   PANTHER
   PTHR10159:SF123 (DUAL SPECIFICITY PROTEIN PHOSPHATASE 10)
3. SSF52799 ((Phosphot...)
   308 - 459
   SUPERFAMILY
   SSF52799 ((Phosphotyrosine protein) phosphatases II)

### GO term prediction

#### Biological Process

GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

#### Molecular Function

GO:0004725 protein tyrosine phosphatase activity
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016791 phosphatase activity
GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity

#### Cellular Component

None predicted.