Protein

## EMLSAP00000013004

Length
753 amino acids

### Protein family membership

- Steroid hormone receptor (IPR001723)
  - Orphan nuclear receptor (IPR003070)

### Domains and repeats

1. Domain
   406 - 481
   - Zinc finger, NHR/GATA-type (IPR013088)
     - Zinc finger, nuclear hormone receptor-type (IPR001628)
   553 - 730
   - Nuclear hormone receptor, ligand-binding, core (IPR000536)
2. Domain
   471 - 750
   - Nuclear hormone receptor, ligand-binding (IPR008946)

1 100 200 300 400 500 600 700 753

### Detailed signature matches

1. IPR001723
   Steroid hormone receptor
   1. PR00398 (STRDHORMONER)
      648 - 663
      PRINTS
      PR00398 (STRDHORMONER)
      709 - 726
      PRINTS
      PR00398 (STRDHORMONER)
      582 - 598
      PRINTS
      PR00398 (STRDHORMONER)
      470 - 480
      PRINTS
      PR00398 (STRDHORMONER)
      561 - 582
      PRINTS
      PR00398 (STRDHORMONER)
2. IPR003070
   Orphan nuclear receptor
   1. PR01284 (NUCLEARECPTR)
      506 - 522
      PRINTS
      PR01284 (NUCLEARECPTR)
      606 - 626
      PRINTS
      PR01284 (NUCLEARECPTR)
      627 - 642
      PRINTS
      PR01284 (NUCLEARECPTR)
      481 - 496
      PRINTS
      PR01284 (NUCLEARECPTR)
      676 - 693
      PRINTS
      PR01284 (NUCLEARECPTR)
      730 - 751
      PRINTS
      PR01284 (NUCLEARECPTR)
      709 - 729
      PRINTS
      PR01284 (NUCLEARECPTR)
3. IPR013088
   Zinc finger, NHR/GATA-type
   1. G3DSA:3.30.50.10
      408 - 470
      GENE3D
      G3DSA:3.30.50.10 (G3DSA:3.30.50.10)
4. IPR001628
   Zinc finger, nuclear hormone receptor-type
   1. PR00047 (STROIDFINGER)
      466 - 474
      PRINTS
      PR00047 (STROIDFINGER)
      409 - 425
      PRINTS
      PR00047 (STROIDFINGER)
      425 - 440
      PRINTS
      PR00047 (STROIDFINGER)
      458 - 466
      PRINTS
      PR00047 (STROIDFINGER)
   2. PS00031 (NUCLEAR_RE...)
      409 - 435
      PROSITE patterns
      PS00031 (NUCLEAR_REC_DBD_1)
   3. PS51030 (NUCLEAR_RE...)
      406 - 481
      PROSITE profiles
      PS51030 (NUCLEAR_REC_DBD_2)
   4. PF00105 (zf-C4)
      408 - 476
      Pfam
      PF00105 (zf-C4)
   5. SM00399 (ZnF_C4)
      406 - 477
      SMART
      SM00399 (ZnF_C4)
5. IPR008946
   Nuclear hormone receptor, ligand-binding
   1. SSF48508 (Nuclear r...)
      480 - 750
      SUPERFAMILY
      SSF48508 (Nuclear receptor ligand-binding domain)
   2. G3DSA:1.10.56...
      471 - 749
      GENE3D
      G3DSA:1.10.565.10 (G3DSA:1.10.565.10)
6. IPR000536
   Nuclear hormone receptor, ligand-binding, core
   1. PF00104 (Hormone_recep)
      553 - 730
      Pfam
      PF00104 (Hormone_recep)
   2. SM00430 (HOLI)
      560 - 721
      SMART
      SM00430 (HOLI)

no IPR
Unintegrated signatures

1. PTHR24085 (NUCLEAR ...)
   266 - 753
   PANTHER
   PTHR24085 (NUCLEAR HORMONE RECEPTOR)
2. SSF57716 (Glucocort...)
   407 - 485
   SUPERFAMILY
   SSF57716 (Glucocorticoid receptor-like (DNA-binding domain))

### GO term prediction

#### Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0043401 steroid hormone mediated signaling pathway

#### Molecular Function

GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding

#### Cellular Component

GO:0005634 nucleus