Protein

## EMLSAP00000009522

Length
4,343 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   291 - 352
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)
     - Zinc finger, FYVE/PHD-type (IPR011011)
       - Zinc finger, PHD-type (IPR001965)
         - Zinc finger, PHD-finger (IPR019787)
   375 - 437
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)
     - Zinc finger, FYVE/PHD-type (IPR011011)
       - Zinc finger, PHD-type (IPR001965)
         - Zinc finger, PHD-finger (IPR019787)
   597 - 708
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)
     - Zinc finger, FYVE/PHD-type (IPR011011)
       - Zinc finger, PHD-type (IPR001965)
         - Zinc finger, PHD-finger (IPR019787)
   723 - 791
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)
     - Zinc finger, FYVE/PHD-type (IPR011011)
       - Zinc finger, PHD-type (IPR001965)
         - Zinc finger, PHD-finger (IPR019787)
   1,429 - 1,496
   - High mobility group box domain (IPR009071)
   3,885 - 3,931
   - Zinc finger, PHD-type (IPR001965)
   3,970 - 4,030
   - FY-rich, N-terminal (IPR003888)
   4,031 - 4,124
   - FY-rich, C-terminal (IPR003889)
   4,204 - 4,326
   - SET domain (IPR001214)
   4,327 - 4,343
   - Post-SET domain (IPR003616)

1 500 1000 1500 2000 2500 3000 3500 4000 4343

### Detailed signature matches

1. IPR013083
   Zinc finger, RING/FYVE/PHD-type
   1. G3DSA:3.30.40.10
      604 - 656
      GENE3D
      G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
      300 - 347
      GENE3D
      G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
      657 - 703
      GENE3D
      G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
      734 - 786
      GENE3D
      G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
      376 - 437
      GENE3D
      G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
2. IPR011011
   Zinc finger, FYVE/PHD-type
   1. SSF57903 (FYVE/PHD ...)
      597 - 657
      SUPERFAMILY
      SSF57903 (FYVE/PHD zinc finger)
      723 - 791
      SUPERFAMILY
      SSF57903 (FYVE/PHD zinc finger)
      291 - 352
      SUPERFAMILY
      SSF57903 (FYVE/PHD zinc finger)
      375 - 434
      SUPERFAMILY
      SSF57903 (FYVE/PHD zinc finger)
      648 - 708
      SUPERFAMILY
      SSF57903 (FYVE/PHD zinc finger)
3. IPR001965
   Zinc finger, PHD-type
   1. SM00249 (PHD)
      3,885 - 3,931
      SMART
      SM00249 (PHD)
      300 - 346
      SMART
      SM00249 (PHD)
      657 - 703
      SMART
      SM00249 (PHD)
      734 - 785
      SMART
      SM00249 (PHD)
      379 - 431
      SMART
      SM00249 (PHD)
      607 - 656
      SMART
      SM00249 (PHD)
4. IPR019787
   Zinc finger, PHD-finger
   1. PF00628 (PHD)
      657 - 703
      Pfam
      PF00628 (PHD)
      300 - 348
      Pfam
      PF00628 (PHD)
   2. PS50016 (ZF_PHD_2)
      605 - 658
      PROSITE profiles
      PS50016 (ZF_PHD_2)
      655 - 705
      PROSITE profiles
      PS50016 (ZF_PHD_2)
      732 - 787
      PROSITE profiles
      PS50016 (ZF_PHD_2)
      377 - 433
      PROSITE profiles
      PS50016 (ZF_PHD_2)
      298 - 348
      PROSITE profiles
      PS50016 (ZF_PHD_2)
5. IPR009071
   High mobility group box domain
   1. SSF47095 (HMG-box)
      1,436 - 1,485
      SUPERFAMILY
      SSF47095 (HMG-box)
   2. G3DSA:1.10.30.10
      1,436 - 1,486
      GENE3D
      G3DSA:1.10.30.10 (G3DSA:1.10.30.10)
   3. SM00398 (HMG)
      1,429 - 1,496
      SMART
      SM00398 (HMG)
6. IPR003888
   FY-rich, N-terminal
   1. PF05964 (FYRN)
      3,975 - 4,027
      Pfam
      PF05964 (FYRN)
   2. PS51542 (FYRN)
      3,970 - 4,030
      PROSITE profiles
      PS51542 (FYRN)
   3. SM00541 (FYRN)
      3,986 - 4,029
      SMART
      SM00541 (FYRN)
7. IPR003889
   FY-rich, C-terminal
   1. PF05965 (FYRC)
      4,032 - 4,120
      Pfam
      PF05965 (FYRC)
   2. SM00542 (FYRC)
      4,035 - 4,124
      SMART
      SM00542 (FYRC)
   3. PS51543 (FYRC)
      4,031 - 4,118
      PROSITE profiles
      PS51543 (FYRC)
8. IPR001214
   SET domain
   1. PF00856 (SET)
      4,215 - 4,319
      Pfam
      PF00856 (SET)
   2. PS50280 (SET)
      4,204 - 4,320
      PROSITE profiles
      PS50280 (SET)
   3. SM00317 (SET)
      4,204 - 4,326
      SMART
      SM00317 (SET)
9. IPR003616
   Post-SET domain
   1. SM00508 (PostSET)
      4,327 - 4,343
      SMART
      SM00508 (PostSET)
   2. PS50868 (POST_SET)
      4,327 - 4,343
      PROSITE profiles
      PS50868 (POST_SET)
10. IPR019786
    Zinc finger, PHD-type, conserved site
    1. PS01359 (ZF_PHD_1)
       269 - 345
       PROSITE patterns
       PS01359 (ZF_PHD_1)
       625 - 702
       PROSITE patterns
       PS01359 (ZF_PHD_1)
       608 - 676
       PROSITE patterns
       PS01359 (ZF_PHD_1)
       348 - 430
       PROSITE patterns
       PS01359 (ZF_PHD_1)

no IPR
Unintegrated signatures

1. Coil
   1,057 - 1,085
   COILS
   Coil (Coil)
   2,173 - 2,194
   COILS
   Coil (Coil)
   2,145 - 2,166
   COILS
   Coil (Coil)
2. G3DSA:2.170.2...
   4,192 - 4,342
   GENE3D
   G3DSA:2.170.270.10 (G3DSA:2.170.270.10)
3. PF13771 (zf-HC5HC2H)
   3,853 - 3,930
   Pfam
   PF13771 (zf-HC5HC2H)
   144 - 220
   Pfam
   PF13771 (zf-HC5HC2H)
4. PTHR22884 (SET DOMA...)
   265 - 4,343
   PANTHER
   PTHR22884 (SET DOMAIN PROTEINS)
5. PTHR22884:SF41 (SUB...)
   265 - 4,343
   PANTHER
   PTHR22884:SF41 (SUBFAMILY NOT NAMED)
6. SSF82199 (SET domain)
   4,188 - 4,343
   SUPERFAMILY
   SSF82199 (SET domain)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0005515 protein binding
GO:0008270 zinc ion binding

#### Cellular Component

GO:0005634 nucleus