Protein

## EMLSAP00000006817

Length
1,539 amino acids

### Protein family membership

- Crotonase superfamily (IPR001753)

- Glucose/ribitol dehydrogenase (IPR002347)
  - Short-chain dehydrogenase/reductase SDR (IPR002198)

### Domains and repeats

1. Domain
   321 - 575
   - NAD(P)-binding domain (IPR016040)
   1,121 - 1,349
   - DNA mismatch repair protein MutS, C-terminal (IPR000432)
   1,362 - 1,514
   - Acyl-CoA N-acyltransferase (IPR016181)
     - GNAT domain (IPR000182)
2. Domain
   800 - 1,147
   - DNA mismatch repair protein MutS, core (IPR007696)
3. Domain
   1,121 - 1,339
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 200 400 600 800 1000 1200 1400 1539

### Detailed signature matches

1. IPR001753
   Crotonase superfamily
   1. PF00378 (ECH)
      42 - 267
      Pfam
      PF00378 (ECH)
2. IPR002347
   Glucose/ribitol dehydrogenase
   1. PR00081 (GDHRDH)
      448 - 464
      PRINTS
      PR00081 (GDHRDH)
      403 - 414
      PRINTS
      PR00081 (GDHRDH)
      508 - 525
      PRINTS
      PR00081 (GDHRDH)
      326 - 343
      PRINTS
      PR00081 (GDHRDH)
3. IPR002198
   Short-chain dehydrogenase/reductase SDR
   1. PF00106 (adh_short)
      326 - 458
      Pfam
      PF00106 (adh_short)
4. IPR016040
   NAD(P)-binding domain
   1. G3DSA:3.40.50...
      321 - 575
      GENE3D
      G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
5. IPR007696
   DNA mismatch repair protein MutS, core
   1. PF05192 (MutS_III)
      823 - 1,113
      Pfam
      PF05192 (MutS_III)
   2. SSF48334 (DNA repai...)
      800 - 1,119
      SUPERFAMILY
      SSF48334 (DNA repair protein MutS, domain III)
   3. SM00533 (MUTSd)
      824 - 1,147
      SMART
      SM00533 (MUTSd)
6. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      1,121 - 1,339
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
7. IPR000432
   DNA mismatch repair protein MutS, C-terminal
   1. PS00486 (DNA_MISMAT...)
      1,258 - 1,274
      PROSITE patterns
      PS00486 (DNA_MISMATCH_REPAIR_2)
   2. SM00534 (MUTSac)
      1,177 - 1,349
      SMART
      SM00534 (MUTSac)
   3. PF00488 (MutS_V)
      1,121 - 1,342
      Pfam
      PF00488 (MutS_V)
8. IPR016181
   Acyl-CoA N-acyltransferase
   1. G3DSA:3.40.63...
      1,362 - 1,514
      GENE3D
      G3DSA:3.40.630.30 (G3DSA:3.40.630.30)
   2. SSF55729 (Acyl-CoA ...)
      1,362 - 1,514
      SUPERFAMILY
      SSF55729 (Acyl-CoA N-acyltransferases (Nat))
9. IPR000182
   GNAT domain
   1. PS51186 (GNAT)
      1,363 - 1,514
      PROSITE profiles
      PS51186 (GNAT)
   2. PF00583 (Acetyltran...)
      1,412 - 1,487
      Pfam
      PF00583 (Acetyltransf_1)

no IPR
Unintegrated signatures

1. G3DSA:1.10.14...
   793 - 991
   GENE3D
   G3DSA:1.10.1420.10 (G3DSA:1.10.1420.10)
2. G3DSA:3.40.50...
   1,121 - 1,341
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. G3DSA:3.90.22...
   30 - 256
   GENE3D
   G3DSA:3.90.226.10 (G3DSA:3.90.226.10)
4. PTHR11361 (DNA MISM...)
   625 - 1,338
   PANTHER
   PTHR11361 (DNA MISMATCH REPAIR MUTS RELATED PROTEINS)
5. PTHR11361:SF20 (MUT...)
   625 - 1,338
   PANTHER
   PTHR11361:SF20 (MUTS HOMOLOG 5)
6. SSF51735 (NAD(P)-bi...)
   325 - 577
   SUPERFAMILY
   SSF51735 (NAD(P)-binding Rossmann-fold domains)
7. SSF52096 (ClpP/crot...)
   34 - 268
   SUPERFAMILY
   SSF52096 (ClpP/crotonase)

### GO term prediction

#### Biological Process

GO:0006298 mismatch repair
GO:0008152 metabolic process

#### Molecular Function

GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0008080 N-acetyltransferase activity
GO:0016491 oxidoreductase activity
GO:0030983 mismatched DNA binding

#### Cellular Component

None predicted.