Protein

## EMLSAP00000001998

Length
1,259 amino acids

### Protein family membership

- Breast cancer type 2 susceptibility protein (IPR015525)

### Domains and repeats

1. Domain
   553 - 628
   - DNA recombination/repair protein BRCA2, helical domain (IPR015252)
   632 - 737
   - Nucleic acid-binding, OB-fold (IPR012340)
   738 - 767
   - Nucleic acid-binding, OB-fold (IPR012340)
   896 - 965
   - Nucleic acid-binding, OB-fold (IPR012340)
   987 - 1,087
   - Nucleic acid-binding, OB-fold (IPR012340)
2. Domain
   633 - 732
   - BRCA2, oligonucleotide/oligosaccharide-binding 1 (IPR015187)
   986 - 1,093
   - BRCA2, oligonucleotide/oligosaccharide-binding 3 (IPR015188)

1 200 400 600 800 1000 1259

### Detailed signature matches

1. IPR015525
   Breast cancer type 2 susceptibility protein
   1. PTHR11289 (BREAST C...)
      556 - 1,209
      PANTHER
      PTHR11289 (BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2)
2. IPR015252
   DNA recombination/repair protein BRCA2, helical domain
   1. PF09169 (BRCA-2_hel...)
      556 - 628
      Pfam
      PF09169 (BRCA-2_helical)
   2. SSF81872 (BRCA2 hel...)
      553 - 627
      SUPERFAMILY
      SSF81872 (BRCA2 helical domain)
3. IPR012340
   Nucleic acid-binding, OB-fold
   1. SSF50249 (Nucleic a...)
      632 - 737
      SUPERFAMILY
      SSF50249 (Nucleic acid-binding proteins)
      987 - 1,085
      SUPERFAMILY
      SSF50249 (Nucleic acid-binding proteins)
      739 - 767
      SUPERFAMILY
      SSF50249 (Nucleic acid-binding proteins)
      899 - 965
      SUPERFAMILY
      SSF50249 (Nucleic acid-binding proteins)
   2. G3DSA:2.40.50...
      896 - 963
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
      738 - 766
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
      987 - 1,087
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
      632 - 733
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
4. IPR015187
   BRCA2, oligonucleotide/oligosaccharide-binding 1
   1. PF09103 (BRCA-2_OB1)
      633 - 732
      Pfam
      PF09103 (BRCA-2_OB1)
5. IPR015188
   BRCA2, oligonucleotide/oligosaccharide-binding 3
   1. PF09104 (BRCA-2_OB3)
      986 - 1,093
      Pfam
      PF09104 (BRCA-2_OB3)

no IPR
Unintegrated signatures

1. SSF81878 (BRCA2 tow...)
   771 - 886
   SUPERFAMILY
   SSF81878 (BRCA2 tower domain)

### GO term prediction

#### Biological Process

GO:0000724 double-strand break repair via homologous recombination
GO:0006281 DNA repair
GO:0006310 DNA recombination

#### Molecular Function

GO:0003697 single-stranded DNA binding

#### Cellular Component

None predicted.