Protein

## EMLSAP00000006587

Length
683 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   2 - 269
   - Cullin repeat-like-containing domain (IPR016159)
   270 - 541
   - Cullin homology (IPR016158)
2. Domain
   2 - 531
   - Cullin, N-terminal (IPR001373)
   628 - 683
   - Winged helix-turn-helix DNA-binding domain (IPR011991)
     - Cullin protein, neddylation domain (IPR019559)
3. Domain
   462 - 529
   - Winged helix-turn-helix DNA-binding domain (IPR011991)
   530 - 628
   - Winged helix-turn-helix DNA-binding domain (IPR011991)
     - Cullin protein, neddylation domain (IPR019559)

1 100 200 300 400 500 600 683

### Detailed signature matches

1. IPR016159
   Cullin repeat-like-containing domain
   1. SSF74788 (Cullin re...)
      2 - 269
      SUPERFAMILY
      SSF74788 (Cullin repeat-like)
2. IPR001373
   Cullin, N-terminal
   1. PF00888 (Cullin)
      2 - 531
      Pfam
      PF00888 (Cullin)
3. IPR016158
   Cullin homology
   1. PS50069 (CULLIN_2)
      273 - 502
      PROSITE profiles
      PS50069 (CULLIN_2)
   2. SSF75632 (Cullin ho...)
      270 - 541
      SUPERFAMILY
      SSF75632 (Cullin homology domain)
   3. SM00182 (CULLIN)
      303 - 452
      SMART
      SM00182 (CULLIN)
4. IPR011991
   Winged helix-turn-helix DNA-binding domain
   1. G3DSA:1.10.10.10
      462 - 529
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
      636 - 683
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
      530 - 628
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
5. IPR019559
   Cullin protein, neddylation domain
   1. SM00884 (Cullin_Nedd8)
      558 - 623
      SMART
      SM00884 (Cullin_Nedd8)
      628 - 677
      SMART
      SM00884 (Cullin_Nedd8)
   2. PF10557 (Cullin_Nedd8)
      636 - 677
      Pfam
      PF10557 (Cullin_Nedd8)
      559 - 623
      Pfam
      PF10557 (Cullin_Nedd8)
6. IPR016157
   Cullin, conserved site
   1. PS01256 (CULLIN_1)
      656 - 683
      PROSITE patterns
      PS01256 (CULLIN_1)

no IPR
Unintegrated signatures

1. G3DSA:1.20.13...
   276 - 383
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
   172 - 275
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
   56 - 171
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
   2 - 53
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
2. G3DSA:4.10.10...
   389 - 461
   GENE3D
   G3DSA:4.10.1030.10 (G3DSA:4.10.1030.10)
3. PTHR11932 (CULLIN)
   1 - 629
   PANTHER
   PTHR11932 (CULLIN)
4. PTHR11932:SF22 (CUL...)
   1 - 629
   PANTHER
   PTHR11932:SF22 (CULLIN 4)
5. SSF46785 ("Winged h...)
   635 - 683
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)
   546 - 628
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)

### GO term prediction

#### Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

#### Molecular Function

GO:0031625 ubiquitin protein ligase binding

#### Cellular Component

GO:0031461 cullin-RING ubiquitin ligase complex