Protein

## EMLSAP00000003855

Length
770 amino acids

### Protein family membership

- DNA helicase (DNA repair), Rad3 type (IPR013020)
  - Xeroderma pigmentosum group D protein (IPR001945)

### Domains and repeats

1. Domain
   7 - 289
   - Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type (IPR014013)
2. Domain
   8 - 286
   - DEAD2 (IPR010614)
     - Helicase-like, DEXD box c2 type (IPR006554)
3. Domain
   13 - 129
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   193 - 263
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   459 - 473
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   538 - 688
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
4. Domain
   275 - 419
   - Domain of unknown function DUF1227 (IPR010643)
   534 - 708
   - ATP-dependent helicase, C-terminal (IPR006555)

1 100 200 300 400 500 600 700 770

### Detailed signature matches

1. IPR013020
   DNA helicase (DNA repair), Rad3 type
   1. TIGR00604
      9 - 717
      UNKNOWN
      TIGR00604 (TIGR00604)
2. IPR001945
   Xeroderma pigmentosum group D protein
   1. PR00852 (XRODRMPGMNTD)
      314 - 332
      PRINTS
      PR00852 (XRODRMPGMNTD)
      339 - 360
      PRINTS
      PR00852 (XRODRMPGMNTD)
      279 - 298
      PRINTS
      PR00852 (XRODRMPGMNTD)
      716 - 736
      PRINTS
      PR00852 (XRODRMPGMNTD)
      501 - 518
      PRINTS
      PR00852 (XRODRMPGMNTD)
      645 - 667
      PRINTS
      PR00852 (XRODRMPGMNTD)
      8 - 25
      PRINTS
      PR00852 (XRODRMPGMNTD)
      378 - 400
      PRINTS
      PR00852 (XRODRMPGMNTD)
      409 - 427
      PRINTS
      PR00852 (XRODRMPGMNTD)
3. IPR014013
   Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type
   1. PS51193 (HELICASE_A...)
      7 - 289
      PROSITE profiles
      PS51193 (HELICASE_ATP_BIND_2)
4. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      193 - 263
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      459 - 473
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      31 - 88
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      538 - 688
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      13 - 129
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      208 - 247
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
5. IPR010614
   DEAD2
   1. PF06733 (DEAD_2)
      72 - 260
      Pfam
      PF06733 (DEAD_2)
6. IPR006554
   Helicase-like, DEXD box c2 type
   1. SM00488 (DEXDc2)
      8 - 286
      SMART
      SM00488 (DEXDc2)
7. IPR010643
   Domain of unknown function DUF1227
   1. PF06777 (DUF1227)
      275 - 419
      Pfam
      PF06777 (DUF1227)
8. IPR006555
   ATP-dependent helicase, C-terminal
   1. SM00491 (HELICc2)
      551 - 695
      SMART
      SM00491 (HELICc2)
   2. PF13307 (Helicase_C_2)
      534 - 708
      Pfam
      PF13307 (Helicase_C_2)

no IPR
Unintegrated signatures

1. Coil
   262 - 283
   COILS
   Coil (Coil)
2. G3DSA:3.40.50...
   12 - 102
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   184 - 246
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PTHR11472 (DNA REPA...)
   1 - 769
   PANTHER
   PTHR11472 (DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER)
4. PTHR11472:SF1 (DNA ...)
   1 - 769
   PANTHER
   PTHR11472:SF1 (DNA REPAIR HELICASE RAD3/XP-D)

### GO term prediction

#### Biological Process

GO:0006139 nucleobase-containing compound metabolic process
GO:0006289 nucleotide-excision repair

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

#### Cellular Component

GO:0005634 nucleus