Protein

## EMLSAP00000004743

Length
1,590 amino acids

### Protein family membership

- ArgK protein (IPR005129)

- NADH:cytochrome b5 reductase (CBR) (IPR001834)

### Domains and repeats

1. Domain
   382 - 716
   - Hermansky-Pudlak syndrome 3, central region (IPR028167)
   1,057 - 1,277
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   1,323 - 1,443
   - Riboflavin synthase-like beta-barrel (IPR017938)
     - Ferredoxin reductase-type FAD-binding domain (IPR017927)
       - Oxidoreductase, FAD-binding domain (IPR008333)
   1,466 - 1,573
   - Oxidoreductase FAD/NAD(P)-binding (IPR001433)

1 200 400 600 800 1000 1200 1400 1590

### Detailed signature matches

1. IPR005129
   ArgK protein
   1. PF03308 (ArgK)
      1,057 - 1,266
      Pfam
      PF03308 (ArgK)
2. IPR001834
   NADH:cytochrome b5 reductase (CBR)
   1. PR00406 (CYTB5RDTASE)
      1,380 - 1,387
      PRINTS
      PR00406 (CYTB5RDTASE)
      1,503 - 1,514
      PRINTS
      PR00406 (CYTB5RDTASE)
      1,426 - 1,440
      PRINTS
      PR00406 (CYTB5RDTASE)
      1,465 - 1,484
      PRINTS
      PR00406 (CYTB5RDTASE)
      1,359 - 1,370
      PRINTS
      PR00406 (CYTB5RDTASE)
      1,559 - 1,567
      PRINTS
      PR00406 (CYTB5RDTASE)
3. IPR028167
   Hermansky-Pudlak syndrome 3, central region
   1. PF14762 (HPS3_Mid)
      382 - 716
      Pfam
      PF14762 (HPS3_Mid)
4. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      1,057 - 1,277
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
5. IPR017938
   Riboflavin synthase-like beta-barrel
   1. SSF63380 (Riboflavi...)
      1,323 - 1,443
      SUPERFAMILY
      SSF63380 (Riboflavin synthase domain-like)
6. IPR017927
   Ferredoxin reductase-type FAD-binding domain
   1. PS51384 (FAD_FR)
      1,328 - 1,441
      PROSITE profiles
      PS51384 (FAD_FR)
7. IPR008333
   Oxidoreductase, FAD-binding domain
   1. PF00970 (FAD_binding_6)
      1,333 - 1,440
      Pfam
      PF00970 (FAD_binding_6)
8. IPR001433
   Oxidoreductase FAD/NAD(P)-binding
   1. PF00175 (NAD_binding_1)
      1,466 - 1,573
      Pfam
      PF00175 (NAD_binding_1)

no IPR
Unintegrated signatures

1. G3DSA:2.40.30.10
   1,322 - 1,427
   GENE3D
   G3DSA:2.40.30.10 (G3DSA:2.40.30.10)
2. G3DSA:3.40.50...
   1,058 - 1,235
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. G3DSA:3.40.50.80
   1,428 - 1,588
   GENE3D
   G3DSA:3.40.50.80 (G3DSA:3.40.50.80)
4. PF14761 (HPS3_N)
   3 - 221
   Pfam
   PF14761 (HPS3_N)
5. PTHR19370 (NADH-CYT...)
   456 - 1,590
   PANTHER
   PTHR19370 (NADH-CYTOCHROME B5 REDUCTASE)
6. PTHR19370:SF4 (NADH...)
   456 - 1,590
   PANTHER
   PTHR19370:SF4 (NADH-CYTOCHROME B5 REDUCTASE)
7. SSF52343 (Ferredoxi...)
   1,428 - 1,589
   SUPERFAMILY
   SSF52343 (Ferredoxin reductase-like, C-terminal NADP-linked domain)
8. TMhelix
   1,293 - 1,315
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0016491 oxidoreductase activity

#### Cellular Component

None predicted.