Protein

## EMLSAP00000001248

Length
934 amino acids

### Protein family membership

- DNA helicase, ATP-dependent, RecQ type (IPR004589)

### Domains and repeats

1. Domain
   269 - 466
   - Helicase, superfamily 1/2, ATP-binding domain (IPR014001)
     - DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
   475 - 642
   - Helicase, C-terminal (IPR001650)
2. Domain
   284 - 606
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 100 200 300 400 500 600 700 800 934

### Detailed signature matches

1. IPR004589
   DNA helicase, ATP-dependent, RecQ type
   1. TIGR00614
      267 - 624
      UNKNOWN
      TIGR00614 (TIGR00614)
2. IPR014001
   Helicase, superfamily 1/2, ATP-binding domain
   1. SM00487 (DEXDc)
      269 - 466
      SMART
      SM00487 (DEXDc)
   2. PS51192 (HELICASE_A...)
      281 - 453
      PROSITE profiles
      PS51192 (HELICASE_ATP_BIND_1)
3. IPR011545
   DNA/RNA helicase, DEAD/DEAH box type, N-terminal
   1. PF00270 (DEAD)
      275 - 440
      Pfam
      PF00270 (DEAD)
4. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      284 - 606
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
5. IPR001650
   Helicase, C-terminal
   1. PF00271 (Helicase_C)
      521 - 594
      Pfam
      PF00271 (Helicase_C)
   2. PS51194 (HELICASE_CTER)
      475 - 642
      PROSITE profiles
      PS51194 (HELICASE_CTER)
   3. SM00490 (HELICc)
      505 - 595
      SMART
      SM00490 (HELICc)

no IPR
Unintegrated signatures

1. Coil
   10 - 31
   COILS
   Coil (Coil)
2. G3DSA:3.40.50...
   456 - 619
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   252 - 448
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PTHR13710 (DNA HELI...)
   64 - 928
   PANTHER
   PTHR13710 (DNA HELICASE RECQ FAMILY MEMBER)
4. PTHR13710:SF1 (ROTH...)
   64 - 928
   PANTHER
   PTHR13710:SF1 (ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4)

### GO term prediction

#### Biological Process

GO:0006310 DNA recombination

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity

#### Cellular Component

None predicted.