Protein

## EMLSAP00000003976

Length
384 amino acids

### Protein family membership

- Dynein regulator LIS1 (IPR017252)

### Domains and repeats

1. Domain
   7 - 39
   - LisH dimerisation motif (IPR006594)
     - LisH dimerisation motif, subgroup (IPR013720)
   105 - 384
   - WD40/YVTN repeat-like-containing domain (IPR015943)
     - WD40-repeat-containing domain (IPR017986)
2. Repeat
   111 - 341
   - WD40 repeat (IPR001680)
   343 - 384
   - WD40 repeat (IPR001680)
3. Repeat
   179 - 193
   - G-protein beta WD-40 repeat (IPR020472)
   285 - 299
   - G-protein beta WD-40 repeat (IPR020472)
   327 - 341
   - G-protein beta WD-40 repeat (IPR020472)

1 50 100 150 200 250 300 350 384

### Detailed signature matches

1. IPR017252
   Dynein regulator LIS1
   1. PIRSF037647 (LisH)
      1 - 383
      PIRSF
      PIRSF037647 (LisH)
2. IPR006594
   LisH dimerisation motif
   1. SM00667 (LisH)
      7 - 39
      SMART
      SM00667 (LisH)
   2. PS50896 (LISH)
      7 - 39
      PROSITE profiles
      PS50896 (LISH)
3. IPR013720
   LisH dimerisation motif, subgroup
   1. PF08513 (LisH)
      9 - 35
      Pfam
      PF08513 (LisH)
4. IPR015943
   WD40/YVTN repeat-like-containing domain
   1. G3DSA:2.130.1...
      105 - 383
      GENE3D
      G3DSA:2.130.10.10 (G3DSA:2.130.10.10)
5. IPR017986
   WD40-repeat-containing domain
   1. SSF50978 (WD40 repe...)
      105 - 381
      SUPERFAMILY
      SSF50978 (WD40 repeat-like)
   2. PS50294 (WD_REPEATS...)
      106 - 384
      PROSITE profiles
      PS50294 (WD_REPEATS_REGION)
6. IPR001680
   WD40 repeat
   1. PS50082 (WD_REPEATS_2)
      160 - 201
      PROSITE profiles
      PS50082 (WD_REPEATS_2)
      308 - 341
      PROSITE profiles
      PS50082 (WD_REPEATS_2)
      202 - 243
      PROSITE profiles
      PS50082 (WD_REPEATS_2)
      118 - 159
      PROSITE profiles
      PS50082 (WD_REPEATS_2)
      350 - 384
      PROSITE profiles
      PS50082 (WD_REPEATS_2)
      282 - 307
      PROSITE profiles
      PS50082 (WD_REPEATS_2)
   2. SM00320 (WD40)
      301 - 340
      SMART
      SM00320 (WD40)
      153 - 192
      SMART
      SM00320 (WD40)
      195 - 234
      SMART
      SM00320 (WD40)
      111 - 150
      SMART
      SM00320 (WD40)
      343 - 382
      SMART
      SM00320 (WD40)
      237 - 298
      SMART
      SM00320 (WD40)
   3. PF00400 (WD40)
      239 - 298
      Pfam
      PF00400 (WD40)
      155 - 192
      Pfam
      PF00400 (WD40)
      345 - 382
      Pfam
      PF00400 (WD40)
      197 - 234
      Pfam
      PF00400 (WD40)
      303 - 340
      Pfam
      PF00400 (WD40)
      115 - 150
      Pfam
      PF00400 (WD40)
7. IPR020472
   G-protein beta WD-40 repeat
   1. PR00320 (GPROTEINBRPT)
      285 - 299
      PRINTS
      PR00320 (GPROTEINBRPT)
      179 - 193
      PRINTS
      PR00320 (GPROTEINBRPT)
      327 - 341
      PRINTS
      PR00320 (GPROTEINBRPT)
8. IPR019775
   WD40 repeat, conserved site
   1. PS00678 (WD_REPEATS_1)
      369 - 383
      PROSITE patterns
      PS00678 (WD_REPEATS_1)
      137 - 151
      PROSITE patterns
      PS00678 (WD_REPEATS_1)
      285 - 299
      PROSITE patterns
      PS00678 (WD_REPEATS_1)
      179 - 193
      PROSITE patterns
      PS00678 (WD_REPEATS_1)
      327 - 341
      PROSITE patterns
      PS00678 (WD_REPEATS_1)

no IPR
Unintegrated signatures

1. Coil
   56 - 77
   COILS
   Coil (Coil)
2. PTHR22847 (WD40 REP...)
   34 - 383
   PANTHER
   PTHR22847 (WD40 REPEAT PROTEIN)
3. PTHR22847:SF250 (SU...)
   34 - 383
   PANTHER
   PTHR22847:SF250 (SUBFAMILY NOT NAMED)
4. SSF109925 (Lissence...)
   2 - 74
   SUPERFAMILY
   SSF109925 (Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0005515 protein binding

#### Cellular Component

None predicted.