Protein

## EMLSAP00000004102

Length
451 amino acids

### Protein family membership

- Isocitrate dehydrogenase NADP-dependent (IPR004790)

### Domains and repeats

1. Domain
   43 - 448
   - Isopropylmalate dehydrogenase-like domain (IPR024084)

1 50 100 150 200 250 300 350 400 451

### Detailed signature matches

1. IPR004790
   Isocitrate dehydrogenase NADP-dependent
   1. PTHR11822 (NADP-SPE...)
      36 - 451
      PANTHER
      PTHR11822 (NADP-SPECIFIC ISOCITRATE DEHYDROGENASE)
   2. TIGR00127
      43 - 449
      UNKNOWN
      TIGR00127 (TIGR00127)
   3. PIRSF000108 (IDH_NADP)
      41 - 451
      PIRSF
      PIRSF000108 (IDH_NADP)
2. IPR024084
   Isopropylmalate dehydrogenase-like domain
   1. G3DSA:3.40.71...
      43 - 448
      GENE3D
      G3DSA:3.40.718.10 (G3DSA:3.40.718.10)
   2. PF00180 (Iso_dh)
      47 - 417
      Pfam
      PF00180 (Iso_dh)
3. IPR019818
   Isocitrate/isopropylmalate dehydrogenase, conserved site
   1. PS00470 (IDH_IMDH)
      310 - 329
      PROSITE patterns
      PS00470 (IDH_IMDH)

no IPR
Unintegrated signatures

1. SSF53659 (Isocitrat...)
   42 - 448
   SUPERFAMILY
   SSF53659 (Isocitrate/Isopropylmalate dehydrogenase-like)

### GO term prediction

#### Biological Process

GO:0006102 isocitrate metabolic process
GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0000287 magnesium ion binding
GO:0004450 isocitrate dehydrogenase (NADP+) activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

#### Cellular Component

None predicted.