Protein

## EMLSAP00000012217

Length
1,271 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   657 - 693
   - Cysteine-rich flanking region, C-terminal (IPR000483)
   906 - 955
   - Cysteine-rich flanking region, C-terminal (IPR000483)
   1,024 - 1,172
   - Toll/interleukin-1 receptor homology (TIR) domain (IPR000157)
2. Repeat
   80 - 103
   - Leucine-rich repeat, typical subtype (IPR003591)
   134 - 157
   - Leucine-rich repeat, typical subtype (IPR003591)
   236 - 259
   - Leucine-rich repeat, typical subtype (IPR003591)
   264 - 286
   - Leucine-rich repeat, typical subtype (IPR003591)
   287 - 312
   - Leucine-rich repeat, typical subtype (IPR003591)
   313 - 336
   - Leucine-rich repeat, typical subtype (IPR003591)
   337 - 359
   - Leucine-rich repeat, typical subtype (IPR003591)
   383 - 405
   - Leucine-rich repeat, typical subtype (IPR003591)
   432 - 454
   - Leucine-rich repeat, typical subtype (IPR003591)
   478 - 501
   - Leucine-rich repeat, typical subtype (IPR003591)
   502 - 524
   - Leucine-rich repeat, typical subtype (IPR003591)
   574 - 595
   - Leucine-rich repeat, typical subtype (IPR003591)
   822 - 845
   - Leucine-rich repeat, typical subtype (IPR003591)
   846 - 869
   - Leucine-rich repeat, typical subtype (IPR003591)
   870 - 891
   - Leucine-rich repeat, typical subtype (IPR003591)
3. Repeat
   82 - 103
   - Leucine-rich repeat (IPR001611)
   136 - 157
   - Leucine-rich repeat (IPR001611)
   160 - 181
   - Leucine-rich repeat (IPR001611)
   195 - 216
   - Leucine-rich repeat (IPR001611)
   217 - 237
   - Leucine-rich repeat (IPR001611)
   238 - 259
   - Leucine-rich repeat (IPR001611)
   265 - 286
   - Leucine-rich repeat (IPR001611)
   289 - 309
   - Leucine-rich repeat (IPR001611)
   315 - 336
   - Leucine-rich repeat (IPR001611)
   339 - 360
   - Leucine-rich repeat (IPR001611)
   384 - 405
   - Leucine-rich repeat (IPR001611)
   408 - 429
   - Leucine-rich repeat (IPR001611)
   433 - 454
   - Leucine-rich repeat (IPR001611)
   457 - 478
   - Leucine-rich repeat (IPR001611)
   480 - 501
   - Leucine-rich repeat (IPR001611)
   504 - 525
   - Leucine-rich repeat (IPR001611)
   527 - 547
   - Leucine-rich repeat (IPR001611)
   549 - 570
   - Leucine-rich repeat (IPR001611)
   574 - 595
   - Leucine-rich repeat (IPR001611)
   824 - 845
   - Leucine-rich repeat (IPR001611)
   848 - 869
   - Leucine-rich repeat (IPR001611)
   872 - 893
   - Leucine-rich repeat (IPR001611)
4. Repeat
   578 - 631
   - Leucine rich repeat 5 (IPR026906)

1 200 400 600 800 1000 1271

### Detailed signature matches

1. IPR000483
   Cysteine-rich flanking region, C-terminal
   1. SM00082 (LRRCT)
      657 - 693
      SMART
      SM00082 (LRRCT)
      906 - 955
      SMART
      SM00082 (LRRCT)
2. IPR000157
   Toll/interleukin-1 receptor homology (TIR) domain
   1. SSF52200 (Toll/Inte...)
      1,024 - 1,171
      SUPERFAMILY
      SSF52200 (Toll/Interleukin receptor TIR domain)
   2. SM00255 (TIR)
      1,031 - 1,172
      SMART
      SM00255 (TIR)
   3. PF01582 (TIR)
      1,034 - 1,106
      Pfam
      PF01582 (TIR)
   4. PS50104 (TIR)
      1,030 - 1,172
      PROSITE profiles
      PS50104 (TIR)
3. IPR003591
   Leucine-rich repeat, typical subtype
   1. SM00369 (LRR_TYP)
      478 - 501
      SMART
      SM00369 (LRR_TYP)
      870 - 891
      SMART
      SM00369 (LRR_TYP)
      287 - 312
      SMART
      SM00369 (LRR_TYP)
      432 - 454
      SMART
      SM00369 (LRR_TYP)
      822 - 845
      SMART
      SM00369 (LRR_TYP)
      337 - 359
      SMART
      SM00369 (LRR_TYP)
      846 - 869
      SMART
      SM00369 (LRR_TYP)
      574 - 595
      SMART
      SM00369 (LRR_TYP)
      264 - 286
      SMART
      SM00369 (LRR_TYP)
      502 - 524
      SMART
      SM00369 (LRR_TYP)
      383 - 405
      SMART
      SM00369 (LRR_TYP)
      80 - 103
      SMART
      SM00369 (LRR_TYP)
      313 - 336
      SMART
      SM00369 (LRR_TYP)
      134 - 157
      SMART
      SM00369 (LRR_TYP)
      236 - 259
      SMART
      SM00369 (LRR_TYP)
4. IPR001611
   Leucine-rich repeat
   1. PS51450 (LRR)
      339 - 360
      PROSITE profiles
      PS51450 (LRR)
      217 - 237
      PROSITE profiles
      PS51450 (LRR)
      289 - 309
      PROSITE profiles
      PS51450 (LRR)
      824 - 845
      PROSITE profiles
      PS51450 (LRR)
      549 - 570
      PROSITE profiles
      PS51450 (LRR)
      872 - 893
      PROSITE profiles
      PS51450 (LRR)
      480 - 501
      PROSITE profiles
      PS51450 (LRR)
      238 - 259
      PROSITE profiles
      PS51450 (LRR)
      433 - 454
      PROSITE profiles
      PS51450 (LRR)
      160 - 181
      PROSITE profiles
      PS51450 (LRR)
      527 - 547
      PROSITE profiles
      PS51450 (LRR)
      384 - 405
      PROSITE profiles
      PS51450 (LRR)
      504 - 525
      PROSITE profiles
      PS51450 (LRR)
      848 - 869
      PROSITE profiles
      PS51450 (LRR)
      457 - 478
      PROSITE profiles
      PS51450 (LRR)
      136 - 157
      PROSITE profiles
      PS51450 (LRR)
      195 - 216
      PROSITE profiles
      PS51450 (LRR)
      408 - 429
      PROSITE profiles
      PS51450 (LRR)
      265 - 286
      PROSITE profiles
      PS51450 (LRR)
      315 - 336
      PROSITE profiles
      PS51450 (LRR)
      574 - 595
      PROSITE profiles
      PS51450 (LRR)
      82 - 103
      PROSITE profiles
      PS51450 (LRR)
5. IPR026906
   Leucine rich repeat 5
   1. PF13306 (LRR_5)
      578 - 631
      Pfam
      PF13306 (LRR_5)

no IPR
Unintegrated signatures

1. G3DSA:3.40.50...
   1,028 - 1,170
   GENE3D
   G3DSA:3.40.50.10140 (G3DSA:3.40.50.10140)
2. G3DSA:3.80.10.10
   415 - 556
   GENE3D
   G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
   76 - 184
   GENE3D
   G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
   557 - 696
   GENE3D
   G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
   195 - 414
   GENE3D
   G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
   742 - 910
   GENE3D
   G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
3. PF13855 (LRR_8)
   480 - 538
   Pfam
   PF13855 (LRR_8)
   823 - 883
   Pfam
   PF13855 (LRR_8)
   237 - 299
   Pfam
   PF13855 (LRR_8)
   125 - 171
   Pfam
   PF13855 (LRR_8)
   304 - 350
   Pfam
   PF13855 (LRR_8)
   73 - 114
   Pfam
   PF13855 (LRR_8)
4. PTHR24365 (TOLL-LIK...)
   81 - 1,172
   PANTHER
   PTHR24365 (TOLL-LIKE RECEPTOR)
5. PTHR24365:SF54 (TOLL-6)
   81 - 1,172
   PANTHER
   PTHR24365:SF54 (TOLL-6)
6. SM00364 (LRR_BAC)
   382 - 401
   SMART
   SM00364 (LRR_BAC)
   193 - 212
   SMART
   SM00364 (LRR_BAC)
   408 - 425
   SMART
   SM00364 (LRR_BAC)
   313 - 333
   SMART
   SM00364 (LRR_BAC)
   870 - 889
   SMART
   SM00364 (LRR_BAC)
   574 - 591
   SMART
   SM00364 (LRR_BAC)
   547 - 566
   SMART
   SM00364 (LRR_BAC)
7. SM00365 (LRR_SD22)
   263 - 289
   SMART
   SM00365 (LRR_SD22)
   846 - 867
   SMART
   SM00365 (LRR_SD22)
   236 - 257
   SMART
   SM00365 (LRR_SD22)
   431 - 452
   SMART
   SM00365 (LRR_SD22)
   313 - 334
   SMART
   SM00365 (LRR_SD22)
   80 - 106
   SMART
   SM00365 (LRR_SD22)
   547 - 568
   SMART
   SM00365 (LRR_SD22)
   193 - 214
   SMART
   SM00365 (LRR_SD22)
   478 - 499
   SMART
   SM00365 (LRR_SD22)
8. SSF52047 (RNI-like)
   76 - 455
   SUPERFAMILY
   SSF52047 (RNI-like)
9. SSF52058 (L domain-...)
   350 - 679
   SUPERFAMILY
   SSF52058 (L domain-like)
   750 - 912
   SUPERFAMILY
   SSF52058 (L domain-like)
10. SignalP-noTM
    1 - 24
    SignalP euk
    SignalP-noTM (SignalP-noTM)
11. TMhelix
    973 - 995
    TMHMM
    TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0007165 signal transduction

#### Molecular Function

GO:0005515 protein binding

#### Cellular Component

None predicted.