Protein

## EMLSAP00000000384

Length
866 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   1 - 81
   - Pleckstrin homology domain (IPR001849)
   204 - 551
   - Rho GTPase activation protein (IPR008936)
     - Ras GTPase-activating protein (IPR001936)
2. Domain
   93 - 219
   - C2 domain (IPR000008)

1 100 200 300 400 500 600 700 800 866

### Detailed signature matches

1. IPR001849
   Pleckstrin homology domain
   1. PS50003 (PH_DOMAIN)
      1 - 81
      PROSITE profiles
      PS50003 (PH_DOMAIN)
2. IPR000008
   C2 domain
   1. SSF49562 (C2 domain...)
      94 - 219
      SUPERFAMILY
      SSF49562 (C2 domain (Calcium/lipid-binding domain, CaLB))
   2. SM00239 (C2)
      93 - 198
      SMART
      SM00239 (C2)
3. IPR008936
   Rho GTPase activation protein
   1. SSF48350 (GTPase ac...)
      228 - 528
      SUPERFAMILY
      SSF48350 (GTPase activation domain, GAP)
4. IPR001936
   Ras GTPase-activating protein
   1. PF00616 (RasGAP)
      277 - 447
      Pfam
      PF00616 (RasGAP)
   2. SM00323 (RasGAP)
      204 - 551
      SMART
      SM00323 (RasGAP)
   3. PS50018 (RAS_GTPASE...)
      255 - 447
      PROSITE profiles
      PS50018 (RAS_GTPASE_ACTIV_2)
   4. G3DSA:1.10.50...
      276 - 482
      GENE3D
      G3DSA:1.10.506.10 (G3DSA:1.10.506.10)
5. IPR023152
   Ras GTPase-activating protein, conserved site
   1. PS00509 (RAS_GTPASE...)
      403 - 417
      PROSITE patterns
      PS00509 (RAS_GTPASE_ACTIV_1)

no IPR
Unintegrated signatures

1. Coil
   720 - 755
   COILS
   Coil (Coil)
   803 - 813
   COILS
   Coil (Coil)
   814 - 824
   COILS
   Coil (Coil)
2. G3DSA:2.60.40...
   94 - 220
   GENE3D
   G3DSA:2.60.40.150 (G3DSA:2.60.40.150)
3. PTHR10194 (RAS GTPA...)
   30 - 539
   PANTHER
   PTHR10194 (RAS GTPASE-ACTIVATING PROTEINS)
4. PTHR10194:SF55 (RAS...)
   30 - 539
   PANTHER
   PTHR10194:SF55 (RAS GTPASE ACTIVATING PROTEIN-RELATED)

### GO term prediction

#### Biological Process

GO:0007165 signal transduction
GO:0051056 regulation of small GTPase mediated signal transduction

#### Molecular Function

GO:0005096 GTPase activator activity
GO:0005515 protein binding

#### Cellular Component

GO:0005622 intracellular