Protein

## EMLSAP00000003975

Length
463 amino acids

### Protein family membership

- Dihydrolipoamide succinyltransferase (IPR006255)

### Domains and repeats

1. Domain
   55 - 148
   - Single hybrid motif (IPR011053)
   223 - 461
   - Chloramphenicol acetyltransferase-like domain (IPR023213)
2. Domain
   56 - 128
   - Biotin/lipoyl attachment (IPR000089)
   233 - 461
   - 2-oxoacid dehydrogenase acyltransferase, catalytic domain (IPR001078)

1 50 100 150 200 250 300 350 400 463

### Detailed signature matches

1. IPR006255
   Dihydrolipoamide succinyltransferase
   1. TIGR01347
      58 - 462
      UNKNOWN
      TIGR01347 (TIGR01347)
2. IPR011053
   Single hybrid motif
   1. SSF51230 (Single hy...)
      55 - 148
      SUPERFAMILY
      SSF51230 (Single hybrid motif)
3. IPR000089
   Biotin/lipoyl attachment
   1. PF00364 (Biotin_lipoyl)
      57 - 128
      Pfam
      PF00364 (Biotin_lipoyl)
   2. PS50968 (BIOTINYL_L...)
      56 - 128
      PROSITE profiles
      PS50968 (BIOTINYL_LIPOYL)
4. IPR023213
   Chloramphenicol acetyltransferase-like domain
   1. G3DSA:3.30.55...
      223 - 461
      GENE3D
      G3DSA:3.30.559.10 (G3DSA:3.30.559.10)
5. IPR001078
   2-oxoacid dehydrogenase acyltransferase, catalytic domain
   1. PF00198 (2-oxoacid_dh)
      233 - 461
      Pfam
      PF00198 (2-oxoacid_dh)
6. IPR003016
   2-oxo acid dehydrogenase, lipoyl-binding site
   1. PS00189 (LIPOYL)
      79 - 108
      PROSITE patterns
      PS00189 (LIPOYL)

no IPR
Unintegrated signatures

1. G3DSA:2.40.50...
   55 - 147
   GENE3D
   G3DSA:2.40.50.100 (G3DSA:2.40.50.100)
2. PTHR23151 (DIHYDROL...)
   37 - 463
   PANTHER
   PTHR23151 (DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED)
3. PTHR23151:SF8 (DIHY...)
   37 - 463
   PANTHER
   PTHR23151:SF8 (DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX)
4. SSF52777 (CoA-depen...)
   233 - 462
   SUPERFAMILY
   SSF52777 (CoA-dependent acyltransferases)

### GO term prediction

#### Biological Process

GO:0006099 tricarboxylic acid cycle
GO:0008152 metabolic process

#### Molecular Function

GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity
GO:0016746 transferase activity, transferring acyl groups

#### Cellular Component

GO:0045252 oxoglutarate dehydrogenase complex