Protein

## EMLSAP00000009873

Length
3,465 amino acids

### Protein family membership

- Pentaxin (IPR001759)

### Domains and repeats

1. Domain
   26 - 240
   - von Willebrand factor, type A (IPR002035)
   350 - 399
   - Epidermal growth factor-like domain (IPR000742)
   477 - 560
   - Hyalin (IPR003410)
   561 - 641
   - Hyalin (IPR003410)
   939 - 995
   - Epidermal growth factor-like domain (IPR000742)
   1,060 - 1,096
   - Epidermal growth factor-like domain (IPR000742)
   1,098 - 1,134
   - Epidermal growth factor-like domain (IPR000742)
   1,136 - 1,175
   - Epidermal growth factor-like domain (IPR000742)
   1,177 - 1,211
   - Epidermal growth factor-like domain (IPR000742)
   1,213 - 1,249
   - Epidermal growth factor-like domain (IPR000742)
   1,251 - 1,297
   - Epidermal growth factor-like domain (IPR000742)
   1,304 - 1,495
   - Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
   1,996 - 2,118
   - Sushi/SCR/CCP (IPR000436)
   2,121 - 2,181
   - Sushi/SCR/CCP (IPR000436)
   3,054 - 3,175
   - Sushi/SCR/CCP (IPR000436)
   3,226 - 3,401
   - Sushi/SCR/CCP (IPR000436)
2. Domain
   293 - 478
   - Sushi/SCR/CCP (IPR000436)
   642 - 705
   - Sushi/SCR/CCP (IPR000436)
   867 - 1,013
   - Insulin-like growth factor binding protein, N-terminal (IPR009030)
   1,503 - 1,558
   - Sushi/SCR/CCP (IPR000436)
   1,599 - 1,867
   - Sushi/SCR/CCP (IPR000436)
   1,868 - 1,996
   - Sushi/SCR/CCP (IPR000436)
   2,179 - 2,299
   - Sushi/SCR/CCP (IPR000436)
   2,300 - 2,498
   - Sushi/SCR/CCP (IPR000436)
   2,500 - 2,574
   - Sushi/SCR/CCP (IPR000436)
   2,575 - 2,639
   - Sushi/SCR/CCP (IPR000436)
   2,640 - 2,946
   - Sushi/SCR/CCP (IPR000436)
   2,948 - 3,009
   - Sushi/SCR/CCP (IPR000436)
   3,173 - 3,228
   - Sushi/SCR/CCP (IPR000436)
   3,399 - 3,457
   - Sushi/SCR/CCP (IPR000436)
3. Domain
   888 - 936
   - Tyrosine-protein kinase ephrin type A/B receptor-like (IPR011641)
   943 - 990
   - Tyrosine-protein kinase ephrin type A/B receptor-like (IPR011641)
   1,061 - 1,096
   - EGF-like calcium-binding domain (IPR001881)
   1,098 - 1,134
   - EGF-like calcium-binding domain (IPR001881)
   1,136 - 1,175
   - EGF-like calcium-binding domain (IPR001881)
   1,177 - 1,211
   - EGF-like calcium-binding domain (IPR001881)
   1,216 - 1,249
   - EGF-like calcium-binding domain (IPR001881)
   1,251 - 1,297
   - EGF-like calcium-binding domain (IPR001881)
   1,307 - 1,493
   - Concanavalin A-like lectin/glucanases superfamily (IPR008985)
   3,226 - 3,401
   - Sushi/SCR/CCP (IPR000436)

1 500 1000 1500 2000 2500 3000 3465

### Detailed signature matches

1. IPR001759
   Pentaxin
   1. PF00354 (Pentaxin)
      1,321 - 1,496
      Pfam
      PF00354 (Pentaxin)
   2. PR00895 (PENTAXIN)
      1,414 - 1,433
      PRINTS
      PR00895 (PENTAXIN)
      1,324 - 1,338
      PRINTS
      PR00895 (PENTAXIN)
      1,345 - 1,359
      PRINTS
      PR00895 (PENTAXIN)
      1,434 - 1,453
      PRINTS
      PR00895 (PENTAXIN)
   3. SM00159 (PTX)
      1,295 - 1,504
      SMART
      SM00159 (PTX)
2. IPR002035
   von Willebrand factor, type A
   1. G3DSA:3.40.50...
      26 - 240
      GENE3D
      G3DSA:3.40.50.410 (G3DSA:3.40.50.410)
   2. SM00327 (VWA)
      28 - 239
      SMART
      SM00327 (VWA)
   3. PS50234 (VWFA)
      30 - 234
      PROSITE profiles
      PS50234 (VWFA)
   4. PF00092 (VWA)
      30 - 227
      Pfam
      PF00092 (VWA)
3. IPR000436
   Sushi/SCR/CCP
   1. PS50923 (SUSHI)
      1,668 - 1,731
      PROSITE profiles
      PS50923 (SUSHI)
      2,367 - 2,437
      PROSITE profiles
      PS50923 (SUSHI)
      2,121 - 2,178
      PROSITE profiles
      PS50923 (SUSHI)
      2,232 - 2,299
      PROSITE profiles
      PS50923 (SUSHI)
      2,948 - 3,009
      PROSITE profiles
      PS50923 (SUSHI)
      2,055 - 2,118
      PROSITE profiles
      PS50923 (SUSHI)
      1,599 - 1,667
      PROSITE profiles
      PS50923 (SUSHI)
      642 - 705
      PROSITE profiles
      PS50923 (SUSHI)
      2,575 - 2,639
      PROSITE profiles
      PS50923 (SUSHI)
      1,796 - 1,867
      PROSITE profiles
      PS50923 (SUSHI)
      354 - 413
      PROSITE profiles
      PS50923 (SUSHI)
      1,503 - 1,558
      PROSITE profiles
      PS50923 (SUSHI)
      2,714 - 2,772
      PROSITE profiles
      PS50923 (SUSHI)
      3,054 - 3,120
      PROSITE profiles
      PS50923 (SUSHI)
      1,997 - 2,054
      PROSITE profiles
      PS50923 (SUSHI)
      1,868 - 1,933
      PROSITE profiles
      PS50923 (SUSHI)
      2,773 - 2,831
      PROSITE profiles
      PS50923 (SUSHI)
      3,284 - 3,339
      PROSITE profiles
      PS50923 (SUSHI)
      3,176 - 3,225
      PROSITE profiles
      PS50923 (SUSHI)
      2,640 - 2,713
      PROSITE profiles
      PS50923 (SUSHI)
      1,934 - 1,996
      PROSITE profiles
      PS50923 (SUSHI)
      3,121 - 3,175
      PROSITE profiles
      PS50923 (SUSHI)
      2,500 - 2,574
      PROSITE profiles
      PS50923 (SUSHI)
      2,890 - 2,946
      PROSITE profiles
      PS50923 (SUSHI)
      2,832 - 2,889
      PROSITE profiles
      PS50923 (SUSHI)
      293 - 353
      PROSITE profiles
      PS50923 (SUSHI)
      3,340 - 3,401
      PROSITE profiles
      PS50923 (SUSHI)
      3,402 - 3,457
      PROSITE profiles
      PS50923 (SUSHI)
      1,732 - 1,795
      PROSITE profiles
      PS50923 (SUSHI)
      414 - 478
      PROSITE profiles
      PS50923 (SUSHI)
      2,300 - 2,366
      PROSITE profiles
      PS50923 (SUSHI)
      3,226 - 3,283
      PROSITE profiles
      PS50923 (SUSHI)
      2,438 - 2,498
      PROSITE profiles
      PS50923 (SUSHI)
   2. SSF57535 (Complemen...)
      2,832 - 2,895
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      1,667 - 1,737
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      410 - 469
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,714 - 2,783
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      1,887 - 1,938
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,885 - 2,945
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      1,734 - 1,801
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,123 - 2,181
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      355 - 423
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      3,173 - 3,228
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,433 - 2,497
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      3,226 - 3,291
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      3,399 - 3,452
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,179 - 2,237
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,226 - 2,284
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      1,626 - 1,679
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      3,055 - 3,132
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      294 - 365
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      1,996 - 2,060
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      1,796 - 1,856
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,774 - 2,843
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,305 - 2,373
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      3,334 - 3,401
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      1,503 - 1,551
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,669 - 2,719
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,368 - 2,445
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      3,302 - 3,345
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
      2,052 - 2,118
      SUPERFAMILY
      SSF57535 (Complement control module/SCR domain)
   3. SM00032 (CCP)
      2,950 - 3,007
      SMART
      SM00032 (CCP)
      3,342 - 3,399
      SMART
      SM00032 (CCP)
      3,228 - 3,281
      SMART
      SM00032 (CCP)
      1,870 - 1,931
      SMART
      SM00032 (CCP)
      3,123 - 3,173
      SMART
      SM00032 (CCP)
      3,286 - 3,337
      SMART
      SM00032 (CCP)
      2,234 - 2,287
      SMART
      SM00032 (CCP)
      2,302 - 2,364
      SMART
      SM00032 (CCP)
      2,658 - 2,711
      SMART
      SM00032 (CCP)
      2,180 - 2,229
      SMART
      SM00032 (CCP)
      1,670 - 1,729
      SMART
      SM00032 (CCP)
      356 - 411
      SMART
      SM00032 (CCP)
      2,440 - 2,496
      SMART
      SM00032 (CCP)
      2,892 - 2,944
      SMART
      SM00032 (CCP)
      2,123 - 2,176
      SMART
      SM00032 (CCP)
      2,369 - 2,435
      SMART
      SM00032 (CCP)
      2,775 - 2,829
      SMART
      SM00032 (CCP)
      644 - 703
      SMART
      SM00032 (CCP)
      1,798 - 1,859
      SMART
      SM00032 (CCP)
      3,178 - 3,223
      SMART
      SM00032 (CCP)
      2,716 - 2,770
      SMART
      SM00032 (CCP)
      2,834 - 2,887
      SMART
      SM00032 (CCP)
      3,056 - 3,118
      SMART
      SM00032 (CCP)
      1,609 - 1,665
      SMART
      SM00032 (CCP)
      1,999 - 2,052
      SMART
      SM00032 (CCP)
      3,404 - 3,455
      SMART
      SM00032 (CCP)
      295 - 351
      SMART
      SM00032 (CCP)
      2,582 - 2,637
      SMART
      SM00032 (CCP)
      416 - 476
      SMART
      SM00032 (CCP)
      1,734 - 1,793
      SMART
      SM00032 (CCP)
      1,936 - 1,994
      SMART
      SM00032 (CCP)
      1,505 - 1,555
      SMART
      SM00032 (CCP)
      2,057 - 2,116
      SMART
      SM00032 (CCP)
   4. PF00084 (Sushi)
      3,356 - 3,399
      Pfam
      PF00084 (Sushi)
      2,716 - 2,770
      Pfam
      PF00084 (Sushi)
      1,886 - 1,931
      Pfam
      PF00084 (Sushi)
      2,073 - 2,116
      Pfam
      PF00084 (Sushi)
      3,056 - 3,113
      Pfam
      PF00084 (Sushi)
      3,228 - 3,281
      Pfam
      PF00084 (Sushi)
      295 - 351
      Pfam
      PF00084 (Sushi)
      2,302 - 2,356
      Pfam
      PF00084 (Sushi)
      2,775 - 2,824
      Pfam
      PF00084 (Sushi)
      2,834 - 2,887
      Pfam
      PF00084 (Sushi)
      2,123 - 2,176
      Pfam
      PF00084 (Sushi)
      1,610 - 1,665
      Pfam
      PF00084 (Sushi)
      1,798 - 1,856
      Pfam
      PF00084 (Sushi)
      1,522 - 1,551
      Pfam
      PF00084 (Sushi)
      356 - 411
      Pfam
      PF00084 (Sushi)
      2,672 - 2,711
      Pfam
      PF00084 (Sushi)
      2,234 - 2,284
      Pfam
      PF00084 (Sushi)
      2,372 - 2,428
      Pfam
      PF00084 (Sushi)
      2,465 - 2,496
      Pfam
      PF00084 (Sushi)
      1,694 - 1,729
      Pfam
      PF00084 (Sushi)
      1,734 - 1,784
      Pfam
      PF00084 (Sushi)
      2,013 - 2,052
      Pfam
      PF00084 (Sushi)
      416 - 470
      Pfam
      PF00084 (Sushi)
4. IPR000742
   Epidermal growth factor-like domain
   1. PF00008 (EGF)
      1,102 - 1,130
      Pfam
      PF00008 (EGF)
   2. PS50026 (EGF_3)
      1,098 - 1,134
      PROSITE profiles
      PS50026 (EGF_3)
      1,251 - 1,297
      PROSITE profiles
      PS50026 (EGF_3)
      1,177 - 1,211
      PROSITE profiles
      PS50026 (EGF_3)
      1,060 - 1,096
      PROSITE profiles
      PS50026 (EGF_3)
      1,136 - 1,175
      PROSITE profiles
      PS50026 (EGF_3)
      1,213 - 1,249
      PROSITE profiles
      PS50026 (EGF_3)
   3. SM00181 (EGF)
      939 - 995
      SMART
      SM00181 (EGF)
      1,063 - 1,096
      SMART
      SM00181 (EGF)
      1,139 - 1,175
      SMART
      SM00181 (EGF)
      350 - 399
      SMART
      SM00181 (EGF)
      1,101 - 1,134
      SMART
      SM00181 (EGF)
      1,216 - 1,249
      SMART
      SM00181 (EGF)
      1,254 - 1,297
      SMART
      SM00181 (EGF)
      1,180 - 1,211
      SMART
      SM00181 (EGF)
5. IPR003410
   Hyalin
   1. PF02494 (HYR)
      477 - 559
      Pfam
      PF02494 (HYR)
      562 - 638
      Pfam
      PF02494 (HYR)
   2. PS50825 (HYR)
      477 - 560
      PROSITE profiles
      PS50825 (HYR)
      561 - 641
      PROSITE profiles
      PS50825 (HYR)
6. IPR009030
   Insulin-like growth factor binding protein, N-terminal
   1. SSF57184 (Growth fa...)
      867 - 1,013
      SUPERFAMILY
      SSF57184 (Growth factor receptor domain)
7. IPR011641
   Tyrosine-protein kinase ephrin type A/B receptor-like
   1. PF07699 (GCC2_GCC3)
      888 - 936
      Pfam
      PF07699 (GCC2_GCC3)
      943 - 990
      Pfam
      PF07699 (GCC2_GCC3)
8. IPR001881
   EGF-like calcium-binding domain
   1. SM00179 (EGF_CA)
      1,216 - 1,249
      SMART
      SM00179 (EGF_CA)
      1,061 - 1,096
      SMART
      SM00179 (EGF_CA)
      1,251 - 1,297
      SMART
      SM00179 (EGF_CA)
      1,098 - 1,134
      SMART
      SM00179 (EGF_CA)
      1,136 - 1,175
      SMART
      SM00179 (EGF_CA)
      1,177 - 1,211
      SMART
      SM00179 (EGF_CA)
   2. PF07645 (EGF_CA)
      1,136 - 1,171
      Pfam
      PF07645 (EGF_CA)
9. IPR013320
   Concanavalin A-like lectin/glucanase, subgroup
   1. G3DSA:2.60.12...
      1,304 - 1,495
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
10. IPR008985
    Concanavalin A-like lectin/glucanases superfamily
    1. SSF49899 (Concanava...)
       1,307 - 1,493
       SUPERFAMILY
       SSF49899 (Concanavalin A-like lectins/glucanases)
11. IPR013032
    EGF-like, conserved site
    1. PS00022 (EGF_1)
       1,084 - 1,095
       PROSITE patterns
       PS00022 (EGF_1)
       1,163 - 1,174
       PROSITE patterns
       PS00022 (EGF_1)
       1,237 - 1,248
       PROSITE patterns
       PS00022 (EGF_1)
       1,122 - 1,133
       PROSITE patterns
       PS00022 (EGF_1)
       1,285 - 1,296
       PROSITE patterns
       PS00022 (EGF_1)
       1,199 - 1,210
       PROSITE patterns
       PS00022 (EGF_1)
    2. PS01186 (EGF_2)
       1,084 - 1,095
       PROSITE patterns
       PS01186 (EGF_2)
       1,199 - 1,210
       PROSITE patterns
       PS01186 (EGF_2)
       277 - 290
       PROSITE patterns
       PS01186 (EGF_2)
       1,163 - 1,174
       PROSITE patterns
       PS01186 (EGF_2)
       1,122 - 1,133
       PROSITE patterns
       PS01186 (EGF_2)
12. IPR018097
    EGF-like calcium-binding, conserved site
    1. PS01187 (EGF_CA)
       1,136 - 1,163
       PROSITE patterns
       PS01187 (EGF_CA)
13. IPR000152
    EGF-type aspartate/asparagine hydroxylation site
    1. PS00010 (ASX_HYDROXYL)
       1,154 - 1,165
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)

no IPR
Unintegrated signatures

1. G3DSA:2.10.25.10
   1,133 - 1,171
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   1,172 - 1,208
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   1,062 - 1,095
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   1,248 - 1,300
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   1,209 - 1,247
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   1,096 - 1,132
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
2. G3DSA:2.10.70.10
   2,179 - 2,230
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   1,733 - 1,797
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,390 - 2,437
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,596 - 2,642
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   1,891 - 1,936
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,305 - 2,370
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,835 - 2,889
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   3,191 - 3,225
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   3,054 - 3,120
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   1,996 - 2,054
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,774 - 2,834
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   294 - 353
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,659 - 2,714
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   1,798 - 1,870
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   414 - 469
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   1,608 - 1,664
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   1,524 - 1,550
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,123 - 2,177
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   3,121 - 3,175
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,438 - 2,496
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,055 - 2,116
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   3,226 - 3,283
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,890 - 2,945
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   354 - 413
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,715 - 2,771
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   2,231 - 2,284
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   1,665 - 1,731
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
   3,335 - 3,401
   GENE3D
   G3DSA:2.10.70.10 (G3DSA:2.10.70.10)
3. PTHR24033 (FAMILY N...)
   146 - 1,499
   PANTHER
   PTHR24033 (FAMILY NOT NAMED)
4. PTHR24033:SF36 (SUB...)
   146 - 1,499
   PANTHER
   PTHR24033:SF36 (SUBFAMILY NOT NAMED)
5. SSF53300 (vWA-like)
   89 - 240
   SUPERFAMILY
   SSF53300 (vWA-like)
   25 - 60
   SUPERFAMILY
   SSF53300 (vWA-like)
6. SSF57196 (EGF/Laminin)
   1,214 - 1,256
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,177 - 1,217
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,099 - 1,141
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,060 - 1,099
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,136 - 1,182
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   1,254 - 1,302
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
7. TMhelix
   58 - 80
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

#### Cellular Component

None predicted.