Protein

## EMLSAP00000006074

Length
478 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   21 - 192
   - Phosphatase tensin type (IPR014019)
   196 - 425
   - C2 domain (IPR000008)
     - Tensin phosphatase, C2 domain (IPR014020)
2. Domain
   109 - 166
   - Dual specificity phosphatase, catalytic domain (IPR000340)

1 50 100 150 200 250 300 350 400 450 478

### Detailed signature matches

1. IPR014019
   Phosphatase tensin type
   1. PS51181 (PPASE_TENSIN)
      21 - 192
      PROSITE profiles
      PS51181 (PPASE_TENSIN)
2. IPR000340
   Dual specificity phosphatase, catalytic domain
   1. PF00782 (DSPc)
      109 - 166
      Pfam
      PF00782 (DSPc)
3. IPR000008
   C2 domain
   1. SSF49562 (C2 domain...)
      201 - 306
      SUPERFAMILY
      SSF49562 (C2 domain (Calcium/lipid-binding domain, CaLB))
4. IPR014020
   Tensin phosphatase, C2 domain
   1. PF10409 (PTEN_C2)
      196 - 421
      Pfam
      PF10409 (PTEN_C2)
   2. PS51182 (C2_TENSIN)
      197 - 425
      PROSITE profiles
      PS51182 (C2_TENSIN)
5. IPR016130
   Protein-tyrosine phosphatase, active site
   1. PS00383 (TYR_PHOSPH...)
      129 - 139
      PROSITE patterns
      PS00383 (TYR_PHOSPHATASE_1)

no IPR
Unintegrated signatures

1. G3DSA:2.60.40...
   389 - 425
   GENE3D
   G3DSA:2.60.40.1110 (G3DSA:2.60.40.1110)
   198 - 306
   GENE3D
   G3DSA:2.60.40.1110 (G3DSA:2.60.40.1110)
2. G3DSA:3.90.19...
   18 - 197
   GENE3D
   G3DSA:3.90.190.10 (G3DSA:3.90.190.10)
3. PTHR12305 (PHOSPHAT...)
   7 - 418
   PANTHER
   PTHR12305 (PHOSPHATASE WITH HOMOLOGY TO TENSIN)
4. SSF52799 ((Phosphot...)
   25 - 191
   SUPERFAMILY
   SSF52799 ((Phosphotyrosine protein) phosphatases II)

### GO term prediction

#### Biological Process

GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

#### Molecular Function

GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016791 phosphatase activity

#### Cellular Component

None predicted.