Protein

## EMLSAP00000001904

Length
423 amino acids

### Protein family membership

- Steroid hormone receptor (IPR001723)
  - Thyroid hormone receptor (IPR001728)

### Domains and repeats

1. Domain
   101 - 398
   - Nuclear hormone receptor, ligand-binding (IPR008946)
2. Domain
   183 - 371
   - Nuclear hormone receptor, ligand-binding, core (IPR000536)

1 50 100 150 200 250 300 350 423

### Detailed signature matches

1. IPR001723
   Steroid hormone receptor
   1. PR00398 (STRDHORMONER)
      219 - 235
      PRINTS
      PR00398 (STRDHORMONER)
      284 - 299
      PRINTS
      PR00398 (STRDHORMONER)
      198 - 219
      PRINTS
      PR00398 (STRDHORMONER)
      353 - 370
      PRINTS
      PR00398 (STRDHORMONER)
2. IPR001728
   Thyroid hormone receptor
   1. PR00546 (THYROIDHORMR)
      195 - 216
      PRINTS
      PR00546 (THYROIDHORMR)
      116 - 134
      PRINTS
      PR00546 (THYROIDHORMR)
      284 - 306
      PRINTS
      PR00546 (THYROIDHORMR)
3. IPR008946
   Nuclear hormone receptor, ligand-binding
   1. SSF48508 (Nuclear r...)
      101 - 398
      SUPERFAMILY
      SSF48508 (Nuclear receptor ligand-binding domain)
   2. G3DSA:1.10.56...
      187 - 398
      GENE3D
      G3DSA:1.10.565.10 (G3DSA:1.10.565.10)
4. IPR000536
   Nuclear hormone receptor, ligand-binding, core
   1. PF00104 (Hormone_recep)
      183 - 371
      Pfam
      PF00104 (Hormone_recep)
   2. SM00430 (HOLI)
      197 - 365
      SMART
      SM00430 (HOLI)

no IPR
Unintegrated signatures

1. PTHR24082 (NUCLEAR ...)
   68 - 409
   PANTHER
   PTHR24082 (NUCLEAR HORMONE RECEPTOR)
2. PTHR24082:SF127 (EC...)
   68 - 409
   PANTHER
   PTHR24082:SF127 (ECDYSONE-INDUCED PROTEIN E78)

### GO term prediction

#### Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0043401 steroid hormone mediated signaling pathway

#### Molecular Function

GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004887 thyroid hormone receptor activity

#### Cellular Component

GO:0005634 nucleus