Protein

## EMLSAP00000003694

Length
718 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   232 - 307
   - DNA-binding domain (IPR016177)
     - Methyl-CpG DNA binding (IPR001739)
   314 - 434
   - Pre-SET domain (IPR007728)
     - Pre-SET zinc-binding sub-group (IPR003606)
   437 - 699
   - SET domain (IPR001214)
   702 - 718
   - Post-SET domain (IPR003616)

1 100 200 300 400 500 600 718

### Detailed signature matches

1. IPR016177
   DNA-binding domain
   1. SSF54171 (DNA-bindi...)
      235 - 305
      SUPERFAMILY
      SSF54171 (DNA-binding domain)
2. IPR001739
   Methyl-CpG DNA binding
   1. G3DSA:3.30.89...
      241 - 300
      GENE3D
      G3DSA:3.30.890.10 (G3DSA:3.30.890.10)
   2. SM00391 (MBD)
      235 - 307
      SMART
      SM00391 (MBD)
   3. PF01429 (MBD)
      244 - 289
      Pfam
      PF01429 (MBD)
   4. PS50982 (MBD)
      232 - 297
      PROSITE profiles
      PS50982 (MBD)
3. IPR007728
   Pre-SET domain
   1. PF05033 (Pre-SET)
      316 - 429
      Pfam
      PF05033 (Pre-SET)
   2. PS50867 (PRE_SET)
      361 - 434
      PROSITE profiles
      PS50867 (PRE_SET)
4. IPR003606
   Pre-SET zinc-binding sub-group
   1. SM00468 (PreSET)
      314 - 421
      SMART
      SM00468 (PreSET)
5. IPR001214
   SET domain
   1. PF00856 (SET)
      448 - 692
      Pfam
      PF00856 (SET)
   2. PS50280 (SET)
      437 - 693
      PROSITE profiles
      PS50280 (SET)
   3. SM00317 (SET)
      437 - 699
      SMART
      SM00317 (SET)
6. IPR003616
   Post-SET domain
   1. PS50868 (POST_SET)
      702 - 718
      PROSITE profiles
      PS50868 (POST_SET)

no IPR
Unintegrated signatures

1. G3DSA:2.170.2...
   625 - 717
   GENE3D
   G3DSA:2.170.270.10 (G3DSA:2.170.270.10)
   307 - 492
   GENE3D
   G3DSA:2.170.270.10 (G3DSA:2.170.270.10)
2. PTHR22884 (SET DOMA...)
   261 - 718
   PANTHER
   PTHR22884 (SET DOMAIN PROTEINS)
3. PTHR22884:SF145 (SU...)
   261 - 718
   PANTHER
   PTHR22884:SF145 (SUBFAMILY NOT NAMED)
4. SSF82199 (SET domain)
   302 - 495
   SUPERFAMILY
   SSF82199 (SET domain)
   631 - 708
   SUPERFAMILY
   SSF82199 (SET domain)

### GO term prediction

#### Biological Process

GO:0034968 histone lysine methylation

#### Molecular Function

GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0018024 histone-lysine N-methyltransferase activity

#### Cellular Component

GO:0005634 nucleus