Protein

## EMLSAP00000000318

Length
740 amino acids

### Protein family membership

- Peptidase, FtsH (IPR005936)

### Domains and repeats

1. Domain
   86 - 175
   - Peptidase M41, FtsH extracellular (IPR011546)
   261 - 510
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
     - AAA+ ATPase domain (IPR003593)
       - ATPase, AAA-type, core (IPR003959)
2. Domain
   502 - 702
   - Peptidase M41 (IPR000642)

1 100 200 300 400 500 600 740

### Detailed signature matches

1. IPR005936
   Peptidase, FtsH
   1. TIGR01241
      192 - 704
      UNKNOWN
      TIGR01241 (TIGR01241)
   2. MF_01458 (FtsH)
      1 - 728
      HAMAP
      MF_01458 (FtsH)
2. IPR011546
   Peptidase M41, FtsH extracellular
   1. PF06480 (FtsH_ext)
      86 - 175
      Pfam
      PF06480 (FtsH_ext)
3. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      261 - 510
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
4. IPR003593
   AAA+ ATPase domain
   1. SM00382 (AAA)
      296 - 436
      SMART
      SM00382 (AAA)
5. IPR003959
   ATPase, AAA-type, core
   1. PF00004 (AAA)
      301 - 433
      Pfam
      PF00004 (AAA)
6. IPR000642
   Peptidase M41
   1. PF01434 (Peptidase_M41)
      502 - 702
      Pfam
      PF01434 (Peptidase_M41)
7. IPR003960
   ATPase, AAA-type, conserved site
   1. PS00674 (AAA)
      404 - 422
      PROSITE patterns
      PS00674 (AAA)

no IPR
Unintegrated signatures

1. G3DSA:1.10.8.60
   443 - 515
   GENE3D
   G3DSA:1.10.8.60 (G3DSA:1.10.8.60)
2. G3DSA:3.40.50...
   261 - 442
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PTHR23076 (METALLOP...)
   57 - 739
   PANTHER
   PTHR23076 (METALLOPROTEASE M41 FTSH)
4. PTHR23076:SF11 (MIT...)
   57 - 739
   PANTHER
   PTHR23076:SF11 (MITOCHONDRIAL RESPIRATORY CHAIN COMPLEXES ASSEMBLY PROTEIN RCA1,AFG3(YEAST)-RELATED)
5. SSF140990 (FtsH pro...)
   521 - 712
   SUPERFAMILY
   SSF140990 (FtsH protease domain-like)
6. SignalP-TM
   1 - 20
   SignalP Gram+ prok
   SignalP-TM (SignalP-TM)
7. TMhelix
   187 - 209
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis

#### Molecular Function

GO:0000166 nucleotide binding
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0017111 nucleoside-triphosphatase activity

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane