Protein

## EMLSAP00000002136

Length
626 amino acids

### Protein family membership

- E3 ubiquitin-protein ligase Parkin (IPR003977)

### Domains and repeats

1. Domain
   29 - 103
   - Ubiquitin domain (IPR000626)
   301 - 364
   - Zinc finger, C6HC-type (IPR002867)

1 100 200 300 400 500 626

### Detailed signature matches

1. IPR003977
   E3 ubiquitin-protein ligase Parkin
   1. PTHR11685:SF2 (PARK...)
      123 - 414
      PANTHER
      PTHR11685:SF2 (PARKIN (UBIQUITIN E3 LIGASE PRKN))
   2. PR01475 (PARKIN)
      208 - 228
      PRINTS
      PR01475 (PARKIN)
      236 - 252
      PRINTS
      PR01475 (PARKIN)
      162 - 185
      PRINTS
      PR01475 (PARKIN)
      317 - 333
      PRINTS
      PR01475 (PARKIN)
      56 - 76
      PRINTS
      PR01475 (PARKIN)
      141 - 156
      PRINTS
      PR01475 (PARKIN)
      192 - 202
      PRINTS
      PR01475 (PARKIN)
      288 - 309
      PRINTS
      PR01475 (PARKIN)
2. IPR000626
   Ubiquitin domain
   1. PS50053 (UBIQUITIN_2)
      29 - 103
      PROSITE profiles
      PS50053 (UBIQUITIN_2)
3. IPR002867
   Zinc finger, C6HC-type
   1. SM00647 (IBR)
      301 - 364
      SMART
      SM00647 (IBR)
   2. PF01485 (IBR)
      301 - 364
      Pfam
      PF01485 (IBR)

no IPR
Unintegrated signatures

1. PTHR11685 (RBR FAMI...)
   123 - 414
   PANTHER
   PTHR11685 (RBR FAMILY (RING FINGER AND IBR DOMAIN-CONTAINING))
2. SSF54236 (Ubiquitin...)
   25 - 112
   SUPERFAMILY
   SSF54236 (Ubiquitin-like)
3. SSF57850 (RING/U-box)
   310 - 367
   SUPERFAMILY
   SSF57850 (RING/U-box)
4. SignalP-noTM
   1 - 16
   SignalP euk
   SignalP-noTM (SignalP-noTM)
5. TMhelix
   528 - 547
   TMHMM
   TMhelix (TMhelix)
   491 - 513
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0004842 ubiquitin-protein ligase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016881 acid-amino acid ligase activity

#### Cellular Component

GO:0005739 mitochondrion
GO:0005829 cytosol