Protein

## EMLSAP00000010500

Length
316 amino acids

### Protein family membership

- Histone H3-K9 methyltransferase (IPR011381)

### Domains and repeats

1. Domain
   43 - 151
   - Pre-SET domain (IPR007728)
     - Pre-SET zinc-binding sub-group (IPR003606)
   154 - 286
   - SET domain (IPR001214)
   298 - 314
   - Post-SET domain (IPR003616)

1 50 100 150 200 250 316

### Detailed signature matches

1. IPR011381
   Histone H3-K9 methyltransferase
   1. PIRSF009343 (SUV39_...)
      1 - 314
      PIRSF
      PIRSF009343 (SUV39_HMTase_SET)
2. IPR007728
   Pre-SET domain
   1. PF05033 (Pre-SET)
      47 - 146
      Pfam
      PF05033 (Pre-SET)
   2. PS50867 (PRE_SET)
      90 - 151
      PROSITE profiles
      PS50867 (PRE_SET)
3. IPR003606
   Pre-SET zinc-binding sub-group
   1. SM00468 (PreSET)
      43 - 138
      SMART
      SM00468 (PreSET)
4. IPR001214
   SET domain
   1. PF00856 (SET)
      166 - 279
      Pfam
      PF00856 (SET)
   2. PS50280 (SET)
      154 - 280
      PROSITE profiles
      PS50280 (SET)
   3. SM00317 (SET)
      154 - 286
      SMART
      SM00317 (SET)
5. IPR003616
   Post-SET domain
   1. PS50868 (POST_SET)
      298 - 314
      PROSITE profiles
      PS50868 (POST_SET)

no IPR
Unintegrated signatures

1. Coil
   26 - 61
   COILS
   Coil (Coil)
2. G3DSA:2.170.2...
   34 - 314
   GENE3D
   G3DSA:2.170.270.10 (G3DSA:2.170.270.10)
3. PTHR22884 (SET DOMA...)
   6 - 314
   PANTHER
   PTHR22884 (SET DOMAIN PROTEINS)
4. PTHR22884:SF25 (HIS...)
   6 - 314
   PANTHER
   PTHR22884:SF25 (HISTONE-LYSINE N-METHYLTRANSFERASE, SUV9)
5. SSF82199 (SET domain)
   38 - 288
   SUPERFAMILY
   SSF82199 (SET domain)

### GO term prediction

#### Biological Process

GO:0034968 histone lysine methylation

#### Molecular Function

GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0018024 histone-lysine N-methyltransferase activity

#### Cellular Component

GO:0005634 nucleus