Protein

## EMLSAP00000005189

Length
1,096 amino acids

### Protein family membership

- XPA (IPR000465)

- AMP deaminase (IPR006329)

### Domains and repeats

1. Domain
   184 - 287
   - DNA binding domain, putative (IPR009061)
     - XPA C- terminal (IPR022656)
   717 - 1,056
   - Adenosine/AMP deaminase domain (IPR001365)

1 100 200 300 400 500 600 700 800 900 1000 1096

### Detailed signature matches

1. IPR000465
   XPA
   1. TIGR00598
      187 - 352
      UNKNOWN
      TIGR00598 (TIGR00598)
2. IPR006329
   AMP deaminase
   1. PTHR11359 (AMP DEAM...)
      471 - 1,055
      PANTHER
      PTHR11359 (AMP DEAMINASE)
3. IPR009061
   DNA binding domain, putative
   1. SSF46955 (Putative ...)
      216 - 286
      SUPERFAMILY
      SSF46955 (Putative DNA-binding domain)
4. IPR022656
   XPA C- terminal
   1. PF05181 (XPA_C)
      218 - 267
      Pfam
      PF05181 (XPA_C)
   2. G3DSA:3.90.53...
      184 - 287
      GENE3D
      G3DSA:3.90.530.10 (G3DSA:3.90.530.10)
5. IPR001365
   Adenosine/AMP deaminase domain
   1. PF00962 (A_deaminase)
      717 - 1,056
      Pfam
      PF00962 (A_deaminase)
6. IPR022652
   Zinc finger, XPA-type, conserved site
   1. PF01286 (XPA_N)
      185 - 214
      Pfam
      PF01286 (XPA_N)
7. IPR006650
   Adenosine/AMP deaminase active site
   1. PS00485 (A_DEAMINASE)
      1,021 - 1,027
      PROSITE patterns
      PS00485 (A_DEAMINASE)

no IPR
Unintegrated signatures

1. Coil
   278 - 299
   COILS
   Coil (Coil)
2. G3DSA:3.20.20...
   717 - 893
   GENE3D
   G3DSA:3.20.20.140 (G3DSA:3.20.20.140)
   925 - 1,054
   GENE3D
   G3DSA:3.20.20.140 (G3DSA:3.20.20.140)
3. SSF51556 (Metallo-d...)
   538 - 1,057
   SUPERFAMILY
   SSF51556 (Metallo-dependent hydrolases)
4. SSF57716 (Glucocort...)
   184 - 214
   SUPERFAMILY
   SSF57716 (Glucocorticoid receptor-like (DNA-binding domain))

### GO term prediction

#### Biological Process

GO:0006188 IMP biosynthetic process
GO:0006289 nucleotide-excision repair
GO:0009168 purine ribonucleoside monophosphate biosynthetic process

#### Molecular Function

GO:0003684 damaged DNA binding
GO:0003876 AMP deaminase activity
GO:0019239 deaminase activity

#### Cellular Component

GO:0005634 nucleus