Protein

## EMLSAP00000005204

Length
1,152 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   69 - 218
   - Peptidase M12B, propeptide (IPR002870)
   480 - 569
   - Blood coagulation inhibitor, Disintegrin (IPR001762)
   718 - 756
   - Epidermal growth factor-like domain (IPR000742)
2. Domain
   262 - 497
   - Metallopeptidase, catalytic domain (IPR024079)
3. Domain
   263 - 474
   - Peptidase M12B, ADAM/reprolysin (IPR001590)
   568 - 713
   - ADAM, cysteine-rich (IPR006586)

1 200 400 600 800 1000 1152

### Detailed signature matches

1. IPR002870
   Peptidase M12B, propeptide
   1. PF01562 (Pep_M12B_p...)
      69 - 218
      Pfam
      PF01562 (Pep_M12B_propep)
2. IPR024079
   Metallopeptidase, catalytic domain
   1. G3DSA:3.40.39...
      262 - 497
      GENE3D
      G3DSA:3.40.390.10 (G3DSA:3.40.390.10)
3. IPR001590
   Peptidase M12B, ADAM/reprolysin
   1. PS50215 (ADAM_MEPRO)
      263 - 474
      PROSITE profiles
      PS50215 (ADAM_MEPRO)
   2. PF01421 (Reprolysin)
      263 - 474
      Pfam
      PF01421 (Reprolysin)
4. IPR001762
   Blood coagulation inhibitor, Disintegrin
   1. SSF57552 (Blood coa...)
      489 - 567
      SUPERFAMILY
      SSF57552 (Blood coagulation inhibitor (disintegrin))
   2. SM00050 (DISIN)
      489 - 567
      SMART
      SM00050 (DISIN)
   3. PF00200 (Disintegrin)
      489 - 566
      Pfam
      PF00200 (Disintegrin)
   4. PS50214 (DISINTEGRIN_2)
      480 - 569
      PROSITE profiles
      PS50214 (DISINTEGRIN_2)
   5. G3DSA:4.10.70.10
      505 - 565
      GENE3D
      G3DSA:4.10.70.10 (G3DSA:4.10.70.10)
5. IPR006586
   ADAM, cysteine-rich
   1. SM00608 (ACR)
      568 - 713
      SMART
      SM00608 (ACR)
   2. PF08516 (ADAM_CR)
      569 - 680
      Pfam
      PF08516 (ADAM_CR)
6. IPR000742
   Epidermal growth factor-like domain
   1. PS50026 (EGF_3)
      718 - 756
      PROSITE profiles
      PS50026 (EGF_3)
7. IPR018358
   Disintegrin, conserved site
   1. PS00427 (DISINTEGRIN_1)
      522 - 542
      PROSITE patterns
      PS00427 (DISINTEGRIN_1)
8. IPR013032
   EGF-like, conserved site
   1. PS00022 (EGF_1)
      744 - 755
      PROSITE patterns
      PS00022 (EGF_1)
   2. PS01186 (EGF_2)
      744 - 755
      PROSITE patterns
      PS01186 (EGF_2)

no IPR
Unintegrated signatures

1. Coil
   44 - 65
   COILS
   Coil (Coil)
2. G3DSA:2.10.25.10
   727 - 758
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
3. PTHR11905 (ADAM (A ...)
   37 - 1,144
   PANTHER
   PTHR11905 (ADAM (A DISINTEGRIN AND METALLOPROTEASE DOMAIN))
4. PTHR11905:SF12 (MIN...)
   37 - 1,144
   PANTHER
   PTHR11905:SF12 (MIND-MELD)
5. SSF55486 (Metallopr...)
   263 - 474
   SUPERFAMILY
   SSF55486 (Metalloproteases ("zincins"), catalytic domain)
6. SignalP-noTM
   1 - 21
   SignalP euk
   SignalP-noTM (SignalP-noTM)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis

#### Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding

#### Cellular Component

None predicted.