Protein

## EMLSAP00000001073

Length
480 amino acids

### Protein family membership

- GPCR kinase (IPR000239)

### Domains and repeats

1. Domain
   30 - 186
   - Regulator of G protein signalling superfamily (IPR016137)
     - Regulator of G protein signalling domain (IPR000342)
   191 - 477
   - Protein kinase-like domain (IPR011009)
     - Protein kinase domain (IPR000719)
       - Serine/threonine- /dual specificity protein kinase, catalytic domain (IPR002290)
2. Domain
   458 - 480
   - AGC-kinase, C-terminal (IPR000961)

1 50 100 150 200 250 300 350 400 450 480

### Detailed signature matches

1. IPR000239
   GPCR kinase
   1. PR00717 (GPCRKINASE)
      174 - 186
      PRINTS
      PR00717 (GPCRKINASE)
      233 - 251
      PRINTS
      PR00717 (GPCRKINASE)
      472 - 480
      PRINTS
      PR00717 (GPCRKINASE)
2. IPR016137
   Regulator of G protein signalling superfamily
   1. SSF48097 (Regulator...)
      30 - 186
      SUPERFAMILY
      SSF48097 (Regulator of G-protein signaling, RGS)
   2. PS50132 (RGS)
      54 - 178
      PROSITE profiles
      PS50132 (RGS)
   3. SM00315 (RGS)
      54 - 178
      SMART
      SM00315 (RGS)
3. IPR000342
   Regulator of G protein signalling domain
   1. PF00615 (RGS)
      55 - 177
      Pfam
      PF00615 (RGS)
4. IPR011009
   Protein kinase-like domain
   1. SSF56112 (Protein k...)
      191 - 477
      SUPERFAMILY
      SSF56112 (Protein kinase-like (PK-like))
5. IPR000719
   Protein kinase domain
   1. PF00069 (Pkinase)
      195 - 457
      Pfam
      PF00069 (Pkinase)
   2. PS50011 (PROTEIN_KI...)
      194 - 457
      PROSITE profiles
      PS50011 (PROTEIN_KINASE_DOM)
6. IPR002290
   Serine/threonine- /dual specificity protein kinase, catalytic domain
   1. SM00220 (S_TKc)
      194 - 457
      SMART
      SM00220 (S_TKc)
7. IPR000961
   AGC-kinase, C-terminal
   1. PS51285 (AGC_KINASE...)
      458 - 480
      PROSITE profiles
      PS51285 (AGC_KINASE_CTER)
8. IPR017441
   Protein kinase, ATP binding site
   1. PS00107 (PROTEIN_KI...)
      200 - 223
      PROSITE patterns
      PS00107 (PROTEIN_KINASE_ATP)
9. IPR008271
   Serine/threonine-protein kinase, active site
   1. PS00108 (PROTEIN_KI...)
      317 - 329
      PROSITE patterns
      PS00108 (PROTEIN_KINASE_ST)

no IPR
Unintegrated signatures

1. G3DSA:1.10.16...
   79 - 161
   GENE3D
   G3DSA:1.10.167.10 (G3DSA:1.10.167.10)
2. G3DSA:1.10.51...
   268 - 469
   GENE3D
   G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
3. G3DSA:3.30.20...
   189 - 267
   GENE3D
   G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
4. PTHR24355 (G PROTEI...)
   3 - 480
   PANTHER
   PTHR24355 (G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE)
5. PTHR24355:SF5 (G PR...)
   3 - 480
   PANTHER
   PTHR24355:SF5 (G PROTEIN-COUPLED RECEPTOR KINASE)

### GO term prediction

#### Biological Process

GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0038032 termination of G-protein coupled receptor signaling pathway

#### Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004703 G-protein coupled receptor kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups

#### Cellular Component

None predicted.