Protein

## EMLSAP00000009771

Length
519 amino acids

### Protein family membership

- Neurotransmitter-gated ion-channel (IPR006201)
  - Gamma-aminobutyric acid A receptor (IPR006028)

### Domains and repeats

1. Domain
   1 - 69
   - C-type lectin fold (IPR016187)
     - C-type lectin-like (IPR016186)
       - C-type lectin (IPR001304)
   162 - 378
   - Neurotransmitter-gated ion-channel ligand-binding (IPR006202)
   383 - 511
   - Neurotransmitter-gated ion-channel transmembrane domain (IPR006029)
2. Repeat
   120 - 158
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)

1 50 100 150 200 250 300 350 400 450 519

### Detailed signature matches

1. IPR006201
   Neurotransmitter-gated ion-channel
   1. PTHR18945 (NEUROTRA...)
      160 - 466
      PANTHER
      PTHR18945 (NEUROTRANSMITTER GATED ION CHANNEL)
   2. PR00252 (NRIONCHANNEL)
      237 - 248
      PRINTS
      PR00252 (NRIONCHANNEL)
      202 - 218
      PRINTS
      PR00252 (NRIONCHANNEL)
      301 - 315
      PRINTS
      PR00252 (NRIONCHANNEL)
2. IPR006028
   Gamma-aminobutyric acid A receptor
   1. PR00253 (GABAARECEPTR)
      381 - 401
      PRINTS
      PR00253 (GABAARECEPTR)
      407 - 428
      PRINTS
      PR00253 (GABAARECEPTR)
      441 - 462
      PRINTS
      PR00253 (GABAARECEPTR)
      493 - 513
      PRINTS
      PR00253 (GABAARECEPTR)
3. IPR016187
   C-type lectin fold
   1. SSF56436 (C-type le...)
      2 - 69
      SUPERFAMILY
      SSF56436 (C-type lectin-like)
4. IPR016186
   C-type lectin-like
   1. G3DSA:3.10.10...
      1 - 69
      GENE3D
      G3DSA:3.10.100.10 (G3DSA:3.10.100.10)
5. IPR001304
   C-type lectin
   1. PS50041 (C_TYPE_LEC...)
      1 - 61
      PROSITE profiles
      PS50041 (C_TYPE_LECTIN_2)
6. IPR006202
   Neurotransmitter-gated ion-channel ligand-binding
   1. PF02931 (Neur_chan_LBD)
      162 - 354
      Pfam
      PF02931 (Neur_chan_LBD)
   2. SSF63712 (Nicotinic...)
      162 - 378
      SUPERFAMILY
      SSF63712 (Nicotinic receptor ligand binding domain-like)
   3. G3DSA:2.70.17...
      162 - 377
      GENE3D
      G3DSA:2.70.170.10 (G3DSA:2.70.170.10)
7. IPR006029
   Neurotransmitter-gated ion-channel transmembrane domain
   1. SSF90112 (Neurotran...)
      383 - 511
      SUPERFAMILY
      SSF90112 (Neurotransmitter-gated ion-channel transmembrane pore)
   2. PF02932 (Neur_chan_...)
      391 - 477
      Pfam
      PF02932 (Neur_chan_memb)
8. IPR002172
   Low-density lipoprotein (LDL) receptor class A repeat
   1. PS50068 (LDLRA_2)
      120 - 156
      PROSITE profiles
      PS50068 (LDLRA_2)
   2. SSF57424 (LDL recep...)
      120 - 158
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
   3. PF00057 (Ldl_recept_a)
      120 - 155
      Pfam
      PF00057 (Ldl_recept_a)
   4. G3DSA:4.10.40...
      121 - 158
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
   5. SM00192 (LDLa)
      120 - 157
      SMART
      SM00192 (LDLa)
9. IPR023415
   Low-density lipoprotein (LDL) receptor class A, conserved site
   1. PS01209 (LDLRA_1)
      133 - 155
      PROSITE patterns
      PS01209 (LDLRA_1)
10. IPR018000
    Neurotransmitter-gated ion-channel, conserved site
    1. PS00236 (NEUROTR_IO...)
       301 - 315
       PROSITE patterns
       PS00236 (NEUROTR_ION_CHANNEL)

no IPR
Unintegrated signatures

1. G3DSA:1.20.58...
   382 - 513
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
2. TMhelix
   443 - 462
   TMHMM
   TMhelix (TMhelix)
   385 - 404
   TMHMM
   TMhelix (TMhelix)
   411 - 428
   TMHMM
   TMhelix (TMhelix)
   490 - 512
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006810 transport
GO:0006811 ion transport

#### Molecular Function

GO:0005230 extracellular ligand-gated ion channel activity
GO:0005515 protein binding
GO:0030246 carbohydrate binding

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane