Protein

## EMLSAP00000011477

Length
1,248 amino acids

### Protein family membership

- Cation-transporting P-type ATPase (IPR001757)

### Domains and repeats

1. Domain
   4 - 77
   - Heavy metal-associated domain, HMA (IPR006121)
   98 - 164
   - Heavy metal-associated domain, HMA (IPR006121)
     - Heavy metal-associated domain, copper ion-binding (IPR006122)
   168 - 232
   - Heavy metal-associated domain, HMA (IPR006121)
   314 - 385
   - Heavy metal-associated domain, HMA (IPR006121)
     - Heavy metal-associated domain, copper ion-binding (IPR006122)
   394 - 463
   - Heavy metal-associated domain, HMA (IPR006121)
     - Heavy metal-associated domain, copper ion-binding (IPR006122)
   788 - 1,205
   - HAD-like domain (IPR023214)
     - P-type ATPase, cytoplasmic domain N (IPR023299)
2. Domain
   486 - 497
   - P-type ATPase, A domain (IPR008250)
   566 - 808
   - P-type ATPase, A domain (IPR008250)

1 200 400 600 800 1000 1248

### Detailed signature matches

1. IPR001757
   Cation-transporting P-type ATPase
   1. TIGR01494
      1,002 - 1,177
      UNKNOWN
      TIGR01494 (TIGR01494)
   2. PR00119 (CATATPASE)
      1,047 - 1,057
      PRINTS
      PR00119 (CATATPASE)
      1,100 - 1,119
      PRINTS
      PR00119 (CATATPASE)
      1,123 - 1,135
      PRINTS
      PR00119 (CATATPASE)
      817 - 831
      PRINTS
      PR00119 (CATATPASE)
      646 - 660
      PRINTS
      PR00119 (CATATPASE)
      1,025 - 1,036
      PRINTS
      PR00119 (CATATPASE)
2. IPR006121
   Heavy metal-associated domain, HMA
   1. SSF55008 (HMA, heav...)
      314 - 385
      SUPERFAMILY
      SSF55008 (HMA, heavy metal-associated domain)
      4 - 58
      SUPERFAMILY
      SSF55008 (HMA, heavy metal-associated domain)
      168 - 232
      SUPERFAMILY
      SSF55008 (HMA, heavy metal-associated domain)
      395 - 463
      SUPERFAMILY
      SSF55008 (HMA, heavy metal-associated domain)
      98 - 162
      SUPERFAMILY
      SSF55008 (HMA, heavy metal-associated domain)
   2. PF00403 (HMA)
      8 - 66
      Pfam
      PF00403 (HMA)
      322 - 381
      Pfam
      PF00403 (HMA)
      102 - 161
      Pfam
      PF00403 (HMA)
      397 - 456
      Pfam
      PF00403 (HMA)
   3. PS50846 (HMA_2)
      319 - 385
      PROSITE profiles
      PS50846 (HMA_2)
      394 - 460
      PROSITE profiles
      PS50846 (HMA_2)
      4 - 77
      PROSITE profiles
      PS50846 (HMA_2)
      168 - 230
      PROSITE profiles
      PS50846 (HMA_2)
      98 - 164
      PROSITE profiles
      PS50846 (HMA_2)
3. IPR006122
   Heavy metal-associated domain, copper ion-binding
   1. TIGR00003
      396 - 458
      UNKNOWN
      TIGR00003 (TIGR00003)
      322 - 382
      UNKNOWN
      TIGR00003 (TIGR00003)
      101 - 162
      UNKNOWN
      TIGR00003 (TIGR00003)
4. IPR008250
   P-type ATPase, A domain
   1. G3DSA:2.70.15...
      486 - 497
      GENE3D
      G3DSA:2.70.150.10 (G3DSA:2.70.150.10)
      585 - 697
      GENE3D
      G3DSA:2.70.150.10 (G3DSA:2.70.150.10)
   2. PF00122 (E1-E2_ATPase)
      566 - 808
      Pfam
      PF00122 (E1-E2_ATPase)
5. IPR023214
   HAD-like domain
   1. PF00702 (Hydrolase)
      813 - 1,114
      Pfam
      PF00702 (Hydrolase)
   2. G3DSA:3.40.50...
      788 - 833
      GENE3D
      G3DSA:3.40.50.1000 (G3DSA:3.40.50.1000)
      1,028 - 1,168
      GENE3D
      G3DSA:3.40.50.1000 (G3DSA:3.40.50.1000)
   3. SSF56784 (HAD-like)
      815 - 835
      SUPERFAMILY
      SSF56784 (HAD-like)
      996 - 1,205
      SUPERFAMILY
      SSF56784 (HAD-like)
6. IPR023299
   P-type ATPase, cytoplasmic domain N
   1. SSF81660 (Metal cat...)
      819 - 895
      SUPERFAMILY
      SSF81660 (Metal cation-transporting ATPase, ATP-binding domain N)
   2. G3DSA:3.40.11...
      843 - 899
      GENE3D
      G3DSA:3.40.1110.10 (G3DSA:3.40.1110.10)
      958 - 1,027
      GENE3D
      G3DSA:3.40.1110.10 (G3DSA:3.40.1110.10)
7. IPR017969
   Heavy-metal-associated, conserved site
   1. PS01047 (HMA_1)
      399 - 429
      PROSITE patterns
      PS01047 (HMA_1)
      103 - 132
      PROSITE patterns
      PS01047 (HMA_1)
      324 - 354
      PROSITE patterns
      PS01047 (HMA_1)
8. IPR018303
   P-type ATPase, phosphorylation site
   1. PS00154 (ATPASE_E1_E2)
      819 - 825
      PROSITE patterns
      PS00154 (ATPASE_E1_E2)

no IPR
Unintegrated signatures

1. Coil
   467 - 488
   COILS
   Coil (Coil)
2. G3DSA:3.30.70...
   5 - 52
   GENE3D
   G3DSA:3.30.70.100 (G3DSA:3.30.70.100)
   395 - 471
   GENE3D
   G3DSA:3.30.70.100 (G3DSA:3.30.70.100)
   171 - 229
   GENE3D
   G3DSA:3.30.70.100 (G3DSA:3.30.70.100)
   315 - 383
   GENE3D
   G3DSA:3.30.70.100 (G3DSA:3.30.70.100)
   98 - 162
   GENE3D
   G3DSA:3.30.70.100 (G3DSA:3.30.70.100)
3. PR00942 (CUATPASEI)
   526 - 546
   PRINTS
   PR00942 (CUATPASEI)
   109 - 127
   PRINTS
   PR00942 (CUATPASEI)
   488 - 509
   PRINTS
   PR00942 (CUATPASEI)
   546 - 571
   PRINTS
   PR00942 (CUATPASEI)
   127 - 144
   PRINTS
   PR00942 (CUATPASEI)
   374 - 394
   PRINTS
   PR00942 (CUATPASEI)
   319 - 344
   PRINTS
   PR00942 (CUATPASEI)
   345 - 368
   PRINTS
   PR00942 (CUATPASEI)
4. PTHR24093 (FAMILY N...)
   324 - 1,221
   PANTHER
   PTHR24093 (FAMILY NOT NAMED)
5. PTHR24093:SF28 (SUB...)
   324 - 1,221
   PANTHER
   PTHR24093:SF28 (SUBFAMILY NOT NAMED)
6. SSF81653 (Calcium A...)
   610 - 696
   SUPERFAMILY
   SSF81653 (Calcium ATPase, transduction domain A)
7. SSF81665 (Calcium A...)
   697 - 809
   SUPERFAMILY
   SSF81665 (Calcium ATPase, transmembrane domain M)
   565 - 594
   SUPERFAMILY
   SSF81665 (Calcium ATPase, transmembrane domain M)
8. TMhelix
   1,156 - 1,178
   TMHMM
   TMhelix (TMhelix)
   713 - 735
   TMHMM
   TMhelix (TMhelix)
   1,188 - 1,210
   TMHMM
   TMhelix (TMhelix)
   489 - 511
   TMHMM
   TMhelix (TMhelix)
   531 - 553
   TMHMM
   TMhelix (TMhelix)
   768 - 790
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006812 cation transport
GO:0006825 copper ion transport
GO:0030001 metal ion transport

#### Molecular Function

GO:0000166 nucleotide binding
GO:0005507 copper ion binding
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding

#### Cellular Component

GO:0016021 integral component of membrane