Protein

## EMLSAP00000007836

Length
1,297 amino acids

### Protein family membership

- DNA-directed DNA polymerase, family B (IPR006172)

### Domains and repeats

1. Domain
   410 - 683
   - Ribonuclease H-like domain (IPR012337)
     - DNA-directed DNA polymerase, family B, exonuclease domain (IPR006133)
   709 - 737
   - DNA polymerase, palm domain (IPR023211)
   858 - 964
   - DNA polymerase, palm domain (IPR023211)
   981 - 1,034
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)
     - Zinc finger, RING-H2-type (IPR024766)
2. Domain
   669 - 954
   - DNA-directed DNA polymerase, family B, multifunctional domain (IPR006134)
   1,027 - 1,164
   - DNA-directed DNA polymerase, family B, multifunctional domain (IPR006134)
   1,207 - 1,277
   - C4-type zinc-finger of DNA polymerase delta (IPR025687)

1 200 400 600 800 1000 1297

### Detailed signature matches

1. IPR006172
   DNA-directed DNA polymerase, family B
   1. PR00106 (DNAPOLB)
      721 - 734
      PRINTS
      PR00106 (DNAPOLB)
      890 - 898
      PRINTS
      PR00106 (DNAPOLB)
      834 - 846
      PRINTS
      PR00106 (DNAPOLB)
   2. SM00486 (POLBc)
      420 - 904
      SMART
      SM00486 (POLBc)
2. IPR012337
   Ribonuclease H-like domain
   1. SSF53098 (Ribonucle...)
      410 - 683
      SUPERFAMILY
      SSF53098 (Ribonuclease H-like)
3. IPR006133
   DNA-directed DNA polymerase, family B, exonuclease domain
   1. PF03104 (DNA_pol_B_...)
      421 - 596
      Pfam
      PF03104 (DNA_pol_B_exo1)
4. IPR006134
   DNA-directed DNA polymerase, family B, multifunctional domain
   1. PF00136 (DNA_pol_B)
      1,027 - 1,164
      Pfam
      PF00136 (DNA_pol_B)
      669 - 954
      Pfam
      PF00136 (DNA_pol_B)
5. IPR023211
   DNA polymerase, palm domain
   1. G3DSA:3.90.16...
      858 - 964
      GENE3D
      G3DSA:3.90.1600.10 (G3DSA:3.90.1600.10)
      709 - 737
      GENE3D
      G3DSA:3.90.1600.10 (G3DSA:3.90.1600.10)
6. IPR013083
   Zinc finger, RING/FYVE/PHD-type
   1. G3DSA:3.30.40.10
      981 - 1,034
      GENE3D
      G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
7. IPR024766
   Zinc finger, RING-H2-type
   1. PF12678 (zf-rbx1)
      982 - 1,034
      Pfam
      PF12678 (zf-rbx1)
8. IPR025687
   C4-type zinc-finger of DNA polymerase delta
   1. PF14260 (zf-C4pol)
      1,207 - 1,277
      Pfam
      PF14260 (zf-C4pol)
9. IPR017964
   DNA-directed DNA polymerase, family B, conserved site
   1. PS00116 (DNA_POLYME...)
      892 - 900
      PROSITE patterns
      PS00116 (DNA_POLYMERASE_B)

no IPR
Unintegrated signatures

1. G3DSA:1.10.28...
   797 - 847
   GENE3D
   G3DSA:1.10.287.690 (G3DSA:1.10.287.690)
2. G3DSA:3.30.42...
   420 - 668
   GENE3D
   G3DSA:3.30.420.10 (G3DSA:3.30.420.10)
3. PTHR10322 (DNA POLY...)
   1 - 1,297
   PANTHER
   PTHR10322 (DNA POLYMERASE CATALYTIC SUBUNIT)
4. PTHR10322:SF5 (DNA ...)
   1 - 1,297
   PANTHER
   PTHR10322:SF5 (DNA POLYMERASE ZETA CATALYTIC SUBUNIT)
5. SSF56672 (DNA/RNA p...)
   778 - 953
   SUPERFAMILY
   SSF56672 (DNA/RNA polymerases)
   669 - 746
   SUPERFAMILY
   SSF56672 (DNA/RNA polymerases)
   1,026 - 1,178
   SUPERFAMILY
   SSF56672 (DNA/RNA polymerases)
6. SSF57850 (RING/U-box)
   981 - 1,035
   SUPERFAMILY
   SSF57850 (RING/U-box)

### GO term prediction

#### Biological Process

GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication

#### Molecular Function

GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008270 zinc ion binding

#### Cellular Component

None predicted.