Protein

## EMLSAP00000001939

Length
2,702 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   8 - 336
   - Armadillo-type fold (IPR016024)
     - Armadillo-like helical (IPR011989)
   370 - 499
   - Ankyrin repeat-containing domain (IPR020683)
   527 - 630
   - Armadillo-type fold (IPR016024)
     - Armadillo-like helical (IPR011989)
   659 - 676
   - Armadillo-type fold (IPR016024)
   860 - 881
   - Armadillo-type fold (IPR016024)
   925 - 999
   - Armadillo-type fold (IPR016024)
     - Armadillo-like helical (IPR011989)
   1,137 - 1,264
   - Sad1/UNC-like, C-terminal (IPR012919)
   1,290 - 1,362
   - Mib-herc2 (IPR010606)
   1,903 - 1,935
   - Armadillo-type fold (IPR016024)
   2,236 - 2,702
   - HECT (IPR000569)
2. Domain
   1,152 - 1,264
   - Galactose-binding domain-like (IPR008979)
3. Repeat
   434 - 466
   - Ankyrin repeat (IPR002110)
   467 - 499
   - Ankyrin repeat (IPR002110)

1 500 1000 1500 2000 2702

### Detailed signature matches

1. IPR016024
   Armadillo-type fold
   1. SSF48371 (ARM repeat)
      938 - 999
      SUPERFAMILY
      SSF48371 (ARM repeat)
      1,903 - 1,935
      SUPERFAMILY
      SSF48371 (ARM repeat)
      8 - 336
      SUPERFAMILY
      SSF48371 (ARM repeat)
      529 - 630
      SUPERFAMILY
      SSF48371 (ARM repeat)
      860 - 881
      SUPERFAMILY
      SSF48371 (ARM repeat)
      659 - 676
      SUPERFAMILY
      SSF48371 (ARM repeat)
2. IPR011989
   Armadillo-like helical
   1. G3DSA:1.25.10.10
      527 - 596
      GENE3D
      G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
      8 - 69
      GENE3D
      G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
      925 - 952
      GENE3D
      G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
      163 - 217
      GENE3D
      G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
3. IPR020683
   Ankyrin repeat-containing domain
   1. PS50297 (ANK_REP_RE...)
      437 - 495
      PROSITE profiles
      PS50297 (ANK_REP_REGION)
   2. G3DSA:1.25.40.20
      370 - 499
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
   3. PF12796 (Ank_2)
      411 - 490
      Pfam
      PF12796 (Ank_2)
   4. SSF48403 (Ankyrin r...)
      374 - 490
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
4. IPR012919
   Sad1/UNC-like, C-terminal
   1. PF07738 (Sad1_UNC)
      1,137 - 1,264
      Pfam
      PF07738 (Sad1_UNC)
5. IPR008979
   Galactose-binding domain-like
   1. G3DSA:2.60.12...
      1,152 - 1,263
      GENE3D
      G3DSA:2.60.120.260 (G3DSA:2.60.120.260)
   2. SSF49785 (Galactose...)
      1,152 - 1,264
      SUPERFAMILY
      SSF49785 (Galactose-binding domain-like)
6. IPR010606
   Mib-herc2
   1. PF06701 (MIB_HERC2)
      1,301 - 1,360
      Pfam
      PF06701 (MIB_HERC2)
   2. PS51416 (MIB_HERC2)
      1,290 - 1,362
      PROSITE profiles
      PS51416 (MIB_HERC2)
7. IPR000569
   HECT
   1. SSF56204 (Hect, E3 ...)
      2,236 - 2,385
      SUPERFAMILY
      SSF56204 (Hect, E3 ligase catalytic domain)
      2,438 - 2,463
      SUPERFAMILY
      SSF56204 (Hect, E3 ligase catalytic domain)
      2,493 - 2,696
      SUPERFAMILY
      SSF56204 (Hect, E3 ligase catalytic domain)
   2. SM00119 (HECTc)
      2,259 - 2,702
      SMART
      SM00119 (HECTc)
   3. PS50237 (HECT)
      2,264 - 2,702
      PROSITE profiles
      PS50237 (HECT)
   4. PF00632 (HECT)
      2,293 - 2,702
      Pfam
      PF00632 (HECT)
8. IPR002110
   Ankyrin repeat
   1. SM00248 (ANK)
      467 - 499
      SMART
      SM00248 (ANK)
      434 - 463
      SMART
      SM00248 (ANK)
   2. PS50088 (ANK_REPEAT)
      437 - 466
      PROSITE profiles
      PS50088 (ANK_REPEAT)

no IPR
Unintegrated signatures

1. Coil
   1,269 - 1,290
   COILS
   Coil (Coil)
2. G3DSA:3.30.21...
   2,441 - 2,548
   GENE3D
   G3DSA:3.30.2160.10 (G3DSA:3.30.2160.10)
3. PTHR11254 (HECT DOM...)
   1 - 2,702
   PANTHER
   PTHR11254 (HECT DOMAIN UBIQUITIN-PROTEIN LIGASE)
4. PTHR11254:SF75 (E3 ...)
   1 - 2,702
   PANTHER
   PTHR11254:SF75 (E3 LIGASE FOR INHIBIN RECEPTOR)
5. SSF159034 (Mib/herc...)
   1,292 - 1,360
   SUPERFAMILY
   SSF159034 (Mib/herc2 domain-like)

### GO term prediction

#### Biological Process

GO:0016567 protein ubiquitination

#### Molecular Function

GO:0004842 ubiquitin-protein ligase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0046872 metal ion binding

#### Cellular Component

None predicted.