Protein

## EMLSAP00000008308

Length
799 amino acids

### Protein family membership

- Sirtuin family (IPR003000)

### Domains and repeats

1. Domain
   25 - 392
   - Sirtuin family, catalytic core domain (IPR026590)
   734 - 792
   - Zinc finger, FYVE-related (IPR017455)
2. Domain
   54 - 92
   - Sirtuin family, catalytic core small domain (IPR026591)
   145 - 169
   - Sirtuin family, catalytic core small domain (IPR026591)
   387 - 525
   - RUN (IPR004012)
   726 - 793
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)
     - Zinc finger, FYVE/PHD-type (IPR011011)
       - FYVE zinc finger (IPR000306)

1 100 200 300 400 500 600 700 799

### Detailed signature matches

1. IPR003000
   Sirtuin family
   1. PF02146 (SIR2)
      43 - 171
      Pfam
      PF02146 (SIR2)
2. IPR026590
   Sirtuin family, catalytic core domain
   1. PS50305 (SIRTUIN)
      25 - 392
      PROSITE profiles
      PS50305 (SIRTUIN)
3. IPR026591
   Sirtuin family, catalytic core small domain
   1. G3DSA:3.30.16...
      145 - 169
      GENE3D
      G3DSA:3.30.1600.10 (G3DSA:3.30.1600.10)
      54 - 92
      GENE3D
      G3DSA:3.30.1600.10 (G3DSA:3.30.1600.10)
4. IPR004012
   RUN
   1. PF02759 (RUN)
      396 - 523
      Pfam
      PF02759 (RUN)
   2. PS50826 (RUN)
      387 - 525
      PROSITE profiles
      PS50826 (RUN)
   3. SM00593 (RUN)
      455 - 523
      SMART
      SM00593 (RUN)
5. IPR013083
   Zinc finger, RING/FYVE/PHD-type
   1. G3DSA:3.30.40.10
      730 - 791
      GENE3D
      G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
6. IPR011011
   Zinc finger, FYVE/PHD-type
   1. SSF57903 (FYVE/PHD ...)
      730 - 793
      SUPERFAMILY
      SSF57903 (FYVE/PHD zinc finger)
7. IPR000306
   FYVE zinc finger
   1. SM00064 (FYVE)
      726 - 793
      SMART
      SM00064 (FYVE)
   2. PF01363 (FYVE)
      730 - 790
      Pfam
      PF01363 (FYVE)
8. IPR017455
   Zinc finger, FYVE-related
   1. PS50178 (ZF_FYVE)
      734 - 792
      PROSITE profiles
      PS50178 (ZF_FYVE)

no IPR
Unintegrated signatures

1. Coil
   525 - 546
   COILS
   Coil (Coil)
   643 - 692
   COILS
   Coil (Coil)
   553 - 581
   COILS
   Coil (Coil)
   702 - 723
   COILS
   Coil (Coil)
2. G3DSA:3.40.50...
   106 - 144
   GENE3D
   G3DSA:3.40.50.1220 (G3DSA:3.40.50.1220)
   491 - 571
   GENE3D
   G3DSA:3.40.50.1220 (G3DSA:3.40.50.1220)
   21 - 53
   GENE3D
   G3DSA:3.40.50.1220 (G3DSA:3.40.50.1220)
3. PTHR22835 (ZINC FIN...)
   353 - 794
   PANTHER
   PTHR22835 (ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN)
4. PTHR22835:SF105 (RU...)
   353 - 794
   PANTHER
   PTHR22835:SF105 (RUN DOMAIN-CONTAINING PROTEIN)
5. SSF140741 (RUN doma...)
   360 - 524
   SUPERFAMILY
   SSF140741 (RUN domain-like)
6. SSF52467 (DHS-like ...)
   7 - 187
   SUPERFAMILY
   SSF52467 (DHS-like NAD/FAD-binding domain)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0046872 metal ion binding
GO:0070403 NAD+ binding

#### Cellular Component

None predicted.