Protein

## EMLSAP00000007845

Length
964 amino acids

### Protein family membership

- Valine-tRNA ligase (IPR002303)

### Domains and repeats

1. Domain
   22 - 211
   - Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
   233 - 373
   - Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain (IPR009008)
   385 - 588
   - Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
   630 - 640
   - Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
   655 - 911
   - Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (IPR009080)
     - Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding (IPR013155)
2. Domain
   35 - 637
   - Aminoacyl-tRNA synthetase, class Ia (IPR002300)

1 100 200 300 400 500 600 700 800 900 964

### Detailed signature matches

1. IPR002303
   Valine-tRNA ligase
   1. TIGR00422
      23 - 946
      UNKNOWN
      TIGR00422 (TIGR00422)
   2. PR00986 (TRNASYNTHVAL)
      58 - 69
      PRINTS
      PR00986 (TRNASYNTHVAL)
      523 - 541
      PRINTS
      PR00986 (TRNASYNTHVAL)
      387 - 400
      PRINTS
      PR00986 (TRNASYNTHVAL)
      491 - 512
      PRINTS
      PR00986 (TRNASYNTHVAL)
      269 - 286
      PRINTS
      PR00986 (TRNASYNTHVAL)
   3. PTHR11946:SF5 (VALY...)
      1 - 913
      PANTHER
      PTHR11946:SF5 (VALYL-TRNA SYNTHETASE)
2. IPR014729
   Rossmann-like alpha/beta/alpha sandwich fold
   1. G3DSA:3.40.50...
      385 - 588
      GENE3D
      G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
      630 - 640
      GENE3D
      G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
      22 - 211
      GENE3D
      G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
3. IPR002300
   Aminoacyl-tRNA synthetase, class Ia
   1. PF00133 (tRNA-synt_1)
      35 - 637
      Pfam
      PF00133 (tRNA-synt_1)
4. IPR009008
   Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
   1. G3DSA:3.90.74...
      236 - 373
      GENE3D
      G3DSA:3.90.740.10 (G3DSA:3.90.740.10)
   2. SSF50677 (ValRS/Ile...)
      233 - 373
      SUPERFAMILY
      SSF50677 (ValRS/IleRS/LeuRS editing domain)
5. IPR009080
   Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
   1. SSF47323 (Anticodon...)
      655 - 911
      SUPERFAMILY
      SSF47323 (Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases)
6. IPR013155
   Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding
   1. PF08264 (Anticodon_1)
      688 - 843
      Pfam
      PF08264 (Anticodon_1)

no IPR
Unintegrated signatures

1. Coil
   907 - 965
   COILS
   Coil (Coil)
2. G3DSA:1.10.73...
   646 - 834
   GENE3D
   G3DSA:1.10.730.10 (G3DSA:1.10.730.10)
3. PTHR11946 (ISOLEUCY...)
   1 - 913
   PANTHER
   PTHR11946 (ISOLEUCYL, LEUCYL, TYROSYL, VALYL AND METHIONYL-TRNA SYNTHETASES)
4. SSF52374 (Nucleotid...)
   22 - 215
   SUPERFAMILY
   SSF52374 (Nucleotidylyl transferase)
   382 - 588
   SUPERFAMILY
   SSF52374 (Nucleotidylyl transferase)
   630 - 640
   SUPERFAMILY
   SSF52374 (Nucleotidylyl transferase)

### GO term prediction

#### Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006438 valyl-tRNA aminoacylation

#### Molecular Function

GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004832 valine-tRNA ligase activity
GO:0005524 ATP binding

#### Cellular Component

None predicted.