Protein

## EMLSAP00000002595

Length
630 amino acids

### Protein family membership

- NMDA receptor (IPR001508)

### Domains and repeats

1. Domain
   12 - 264
   - Periplasmic binding protein-like I (IPR028082)
   273 - 304
   - Glutamate receptor, L-glutamate/glycine-binding (IPR019594)
2. Domain
   61 - 113
   - Extracellular ligand-binding receptor (IPR001828)
   122 - 251
   - Extracellular ligand-binding receptor (IPR001828)
   257 - 581
   - Ionotropic glutamate receptor (IPR001320)

1 100 200 300 400 500 630

### Detailed signature matches

1. IPR001508
   NMDA receptor
   1. PR00177 (NMDARECEPTOR)
      335 - 360
      PRINTS
      PR00177 (NMDARECEPTOR)
      407 - 434
      PRINTS
      PR00177 (NMDARECEPTOR)
2. IPR028082
   Periplasmic binding protein-like I
   1. SSF53822 (Periplasm...)
      12 - 264
      SUPERFAMILY
      SSF53822 (Periplasmic binding protein-like I)
3. IPR001828
   Extracellular ligand-binding receptor
   1. PF01094 (ANF_receptor)
      122 - 251
      Pfam
      PF01094 (ANF_receptor)
      61 - 113
      Pfam
      PF01094 (ANF_receptor)
4. IPR001320
   Ionotropic glutamate receptor
   1. PF00060 (Lig_chan)
      332 - 581
      Pfam
      PF00060 (Lig_chan)
   2. SM00079 (PBPe)
      257 - 546
      SMART
      SM00079 (PBPe)
5. IPR019594
   Glutamate receptor, L-glutamate/glycine-binding
   1. PF10613 (Lig_chan-G...)
      273 - 304
      Pfam
      PF10613 (Lig_chan-Glu_bd)

no IPR
Unintegrated signatures

1. G3DSA:1.10.28...
   328 - 463
   GENE3D
   G3DSA:1.10.287.70 (G3DSA:1.10.287.70)
2. G3DSA:3.40.19...
   464 - 507
   GENE3D
   G3DSA:3.40.190.10 (G3DSA:3.40.190.10)
   510 - 547
   GENE3D
   G3DSA:3.40.190.10 (G3DSA:3.40.190.10)
   273 - 327
   GENE3D
   G3DSA:3.40.190.10 (G3DSA:3.40.190.10)
3. G3DSA:3.40.50...
   144 - 244
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
   3 - 53
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
   54 - 122
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
4. PTHR18966 (IONOTROP...)
   54 - 616
   PANTHER
   PTHR18966 (IONOTROPIC GLUTAMATE RECEPTOR)
5. PTHR18966:SF38 (GLU...)
   54 - 616
   PANTHER
   PTHR18966:SF38 (GLUTAMATE RECEPTOR, IONOTROPIC, KAINATE 3)
6. SSF53850 (Periplasm...)
   434 - 546
   SUPERFAMILY
   SSF53850 (Periplasmic binding protein-like II)
   272 - 343
   SUPERFAMILY
   SSF53850 (Periplasmic binding protein-like II)
7. TMhelix
   411 - 433
   TMHMM
   TMhelix (TMhelix)
   335 - 354
   TMHMM
   TMhelix (TMhelix)
   572 - 594
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006811 ion transport

#### Molecular Function

GO:0004872 receptor activity
GO:0004970 ionotropic glutamate receptor activity
GO:0005216 ion channel activity
GO:0005234 extracellular-glutamate-gated ion channel activity

#### Cellular Component

GO:0016020 membrane