Protein

## EMLSAP00000010458

Length
441 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   108 - 277
   - Dbl homology (DH) domain (IPR000219)
   281 - 429
   - Pleckstrin homology-like domain (IPR011993)
     - Pleckstrin homology domain (IPR001849)

1 50 100 150 200 250 300 350 400 441

### Detailed signature matches

1. IPR000219
   Dbl homology (DH) domain
   1. SM00325 (RhoGEF)
      120 - 275
      SMART
      SM00325 (RhoGEF)
   2. SSF48065 (DBL homol...)
      111 - 277
      SUPERFAMILY
      SSF48065 (DBL homology domain (DH-domain))
   3. PF00621 (RhoGEF)
      156 - 275
      Pfam
      PF00621 (RhoGEF)
   4. G3DSA:1.20.90...
      108 - 277
      GENE3D
      G3DSA:1.20.900.10 (G3DSA:1.20.900.10)
   5. PS50010 (DH_2)
      144 - 276
      PROSITE profiles
      PS50010 (DH_2)
2. IPR011993
   Pleckstrin homology-like domain
   1. G3DSA:2.30.29.30
      281 - 422
      GENE3D
      G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
3. IPR001849
   Pleckstrin homology domain
   1. PF00169 (PH)
      290 - 423
      Pfam
      PF00169 (PH)
   2. SM00233 (PH)
      289 - 429
      SMART
      SM00233 (PH)
   3. PS50003 (PH_DOMAIN)
      288 - 427
      PROSITE profiles
      PS50003 (PH_DOMAIN)

no IPR
Unintegrated signatures

1. Coil
   236 - 257
   COILS
   Coil (Coil)
2. PTHR22826 (RHO GUAN...)
   39 - 441
   PANTHER
   PTHR22826 (RHO GUANINE EXCHANGE FACTOR-RELATED)
3. PTHR22826:SF51 (STI...)
   39 - 441
   PANTHER
   PTHR22826:SF51 (STILL LIFE PROTEIN, SIF (T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN) (TIAM PROTEIN))
4. SSF50729 (PH domain...)
   271 - 428
   SUPERFAMILY
   SSF50729 (PH domain-like)

### GO term prediction

#### Biological Process

GO:0035023 regulation of Rho protein signal transduction

#### Molecular Function

GO:0005089 Rho guanyl-nucleotide exchange factor activity

#### Cellular Component

None predicted.