Protein

## EMLSAP00000005835

Length
1,047 amino acids

### Protein family membership

- Saposin (IPR008373)

### Domains and repeats

1. Domain
   22 - 62
   - Saposin type A (IPR003119)
   67 - 147
   - Saposin-like (IPR011001)
   164 - 236
   - Saposin-like (IPR011001)
   251 - 353
   - Saposin-like (IPR011001)
   462 - 709
   - Saposin-like (IPR011001)
   727 - 807
   - Saposin-like (IPR011001)
   820 - 1,002
   - Saposin-like (IPR011001)
   1,016 - 1,047
   - Saposin type A (IPR003119)
2. Domain
   66 - 148
   - Saposin B (IPR008139)
   161 - 239
   - Saposin B (IPR008139)
   250 - 332
   - Saposin B (IPR008139)
   464 - 544
   - Saposin B (IPR008139)
   549 - 630
   - Saposin B (IPR008139)
   635 - 716
   - Saposin B (IPR008139)
   727 - 809
   - Saposin B (IPR008139)
   819 - 899
   - Saposin B (IPR008139)
   925 - 1,005
   - Saposin B (IPR008139)
3. Domain
   68 - 105
   - Saposin-like type B, 1 (IPR007856)
   112 - 144
   - Saposin-like type B, 2 (IPR008138)
   467 - 498
   - Saposin-like type B, 1 (IPR007856)
   506 - 540
   - Saposin-like type B, 2 (IPR008138)
   551 - 588
   - Saposin-like type B, 1 (IPR007856)
   592 - 626
   - Saposin-like type B, 2 (IPR008138)
   638 - 674
   - Saposin-like type B, 1 (IPR007856)
   730 - 765
   - Saposin-like type B, 1 (IPR007856)
   771 - 805
   - Saposin-like type B, 2 (IPR008138)

1 100 200 300 400 500 600 700 800 900 1047

### Detailed signature matches

1. IPR008373
   Saposin
   1. PR01797 (SAPOSIN)
      496 - 518
      PRINTS
      PR01797 (SAPOSIN)
      51 - 71
      PRINTS
      PR01797 (SAPOSIN)
      518 - 541
      PRINTS
      PR01797 (SAPOSIN)
      22 - 46
      PRINTS
      PR01797 (SAPOSIN)
      134 - 152
      PRINTS
      PR01797 (SAPOSIN)
2. IPR003119
   Saposin type A
   1. PS51110 (SAP_A)
      1,016 - 1,047
      PROSITE profiles
      PS51110 (SAP_A)
      22 - 62
      PROSITE profiles
      PS51110 (SAP_A)
   2. SM00162 (SAPA)
      1,019 - 1,045
      SMART
      SM00162 (SAPA)
      25 - 58
      SMART
      SM00162 (SAPA)
   3. PF02199 (SapA)
      26 - 58
      Pfam
      PF02199 (SapA)
      1,021 - 1,045
      Pfam
      PF02199 (SapA)
3. IPR008139
   Saposin B
   1. SM00741 (SapB)
      163 - 235
      SMART
      SM00741 (SapB)
      68 - 144
      SMART
      SM00741 (SapB)
      927 - 1,001
      SMART
      SM00741 (SapB)
      729 - 805
      SMART
      SM00741 (SapB)
      252 - 328
      SMART
      SM00741 (SapB)
      637 - 712
      SMART
      SM00741 (SapB)
      466 - 540
      SMART
      SM00741 (SapB)
      821 - 895
      SMART
      SM00741 (SapB)
      551 - 626
      SMART
      SM00741 (SapB)
   2. PS50015 (SAP_B)
      464 - 544
      PROSITE profiles
      PS50015 (SAP_B)
      727 - 809
      PROSITE profiles
      PS50015 (SAP_B)
      66 - 148
      PROSITE profiles
      PS50015 (SAP_B)
      549 - 630
      PROSITE profiles
      PS50015 (SAP_B)
      250 - 332
      PROSITE profiles
      PS50015 (SAP_B)
      161 - 239
      PROSITE profiles
      PS50015 (SAP_B)
      819 - 899
      PROSITE profiles
      PS50015 (SAP_B)
      635 - 716
      PROSITE profiles
      PS50015 (SAP_B)
      925 - 1,005
      PROSITE profiles
      PS50015 (SAP_B)
4. IPR011001
   Saposin-like
   1. G3DSA:1.10.22...
      638 - 709
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
      68 - 141
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
      927 - 1,002
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
      727 - 807
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
      820 - 896
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
      551 - 626
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
      252 - 329
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
      164 - 236
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
      467 - 541
      GENE3D
      G3DSA:1.10.225.10 (G3DSA:1.10.225.10)
   2. SSF47862 (Saposin)
      462 - 502
      SUPERFAMILY
      SSF47862 (Saposin)
      295 - 353
      SUPERFAMILY
      SSF47862 (Saposin)
      728 - 807
      SUPERFAMILY
      SSF47862 (Saposin)
      164 - 236
      SUPERFAMILY
      SSF47862 (Saposin)
      505 - 588
      SUPERFAMILY
      SSF47862 (Saposin)
      251 - 329
      SUPERFAMILY
      SSF47862 (Saposin)
      862 - 964
      SUPERFAMILY
      SSF47862 (Saposin)
      67 - 147
      SUPERFAMILY
      SSF47862 (Saposin)
      591 - 674
      SUPERFAMILY
      SSF47862 (Saposin)
5. IPR007856
   Saposin-like type B, 1
   1. PF05184 (SapB_1)
      467 - 498
      Pfam
      PF05184 (SapB_1)
      638 - 674
      Pfam
      PF05184 (SapB_1)
      551 - 588
      Pfam
      PF05184 (SapB_1)
      68 - 105
      Pfam
      PF05184 (SapB_1)
      730 - 765
      Pfam
      PF05184 (SapB_1)
6. IPR008138
   Saposin-like type B, 2
   1. PF03489 (SapB_2)
      592 - 626
      Pfam
      PF03489 (SapB_2)
      506 - 540
      Pfam
      PF03489 (SapB_2)
      112 - 144
      Pfam
      PF03489 (SapB_2)
      771 - 805
      Pfam
      PF03489 (SapB_2)

no IPR
Unintegrated signatures

1. Coil
   639 - 660
   COILS
   Coil (Coil)
2. PTHR11480 (SAPOSIN-...)
   1 - 736
   PANTHER
   PTHR11480 (SAPOSIN-RELATED)
3. PTHR11480:SF3 (SAPOSIN)
   1 - 736
   PANTHER
   PTHR11480:SF3 (SAPOSIN)
4. SignalP-TM
   1 - 26
   SignalP Gram+ prok
   SignalP-TM (SignalP-TM)
5. SignalP-noTM
   1 - 21
   SignalP Gram- prok
   SignalP-noTM (SignalP-noTM)
   1 - 21
   SignalP Gram- prok
   SignalP-noTM (SignalP-noTM)

### GO term prediction

#### Biological Process

GO:0006629 lipid metabolic process
GO:0006665 sphingolipid metabolic process

#### Molecular Function

None predicted.

#### Cellular Component

GO:0005764 lysosome