Protein

## EMLSAP00000005320

Length
563 amino acids

### Protein family membership

- GPCR, family 3 (IPR000337)

- GPCR, family 3, gamma-aminobutyric acid receptor, type B (IPR002455)

### Domains and repeats

1. Domain
   1 - 205
   - Extracellular ligand-binding receptor (IPR001828)
   340 - 563
   - GPCR, family 3, C-terminal (IPR017978)
2. Domain
   2 - 253
   - Periplasmic binding protein-like I (IPR028082)
   267 - 317
   - GPCR, family 3, nine cysteines domain (IPR011500)

1 100 200 300 400 500 563

### Detailed signature matches

1. IPR000337
   GPCR, family 3
   1. PR00248 (GPCRMGR)
      34 - 53
      PRINTS
      PR00248 (GPCRMGR)
      53 - 69
      PRINTS
      PR00248 (GPCRMGR)
      1 - 27
      PRINTS
      PR00248 (GPCRMGR)
      69 - 86
      PRINTS
      PR00248 (GPCRMGR)
2. IPR002455
   GPCR, family 3, gamma-aminobutyric acid receptor, type B
   1. PR01176 (GABABRECEPTR)
      405 - 424
      PRINTS
      PR01176 (GABABRECEPTR)
      41 - 60
      PRINTS
      PR01176 (GABABRECEPTR)
      458 - 483
      PRINTS
      PR01176 (GABABRECEPTR)
      6 - 34
      PRINTS
      PR01176 (GABABRECEPTR)
3. IPR001828
   Extracellular ligand-binding receptor
   1. PF01094 (ANF_receptor)
      1 - 205
      Pfam
      PF01094 (ANF_receptor)
4. IPR028082
   Periplasmic binding protein-like I
   1. SSF53822 (Periplasm...)
      2 - 253
      SUPERFAMILY
      SSF53822 (Periplasmic binding protein-like I)
5. IPR011500
   GPCR, family 3, nine cysteines domain
   1. PF07562 (NCD3G)
      267 - 317
      Pfam
      PF07562 (NCD3G)
6. IPR017978
   GPCR, family 3, C-terminal
   1. PS50259 (G_PROTEIN_...)
      340 - 563
      PROSITE profiles
      PS50259 (G_PROTEIN_RECEP_F3_4)
   2. PF00003 (7tm_3)
      350 - 558
      Pfam
      PF00003 (7tm_3)

no IPR
Unintegrated signatures

1. G3DSA:3.40.50...
   2 - 51
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
   52 - 213
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
2. PTHR24060 (METABOTR...)
   2 - 555
   PANTHER
   PTHR24060 (METABOTROPIC GLUTAMATE RECEPTOR)
3. TMhelix
   376 - 398
   TMHMM
   TMhelix (TMhelix)
   452 - 474
   TMHMM
   TMhelix (TMhelix)
   403 - 425
   TMHMM
   TMhelix (TMhelix)
   501 - 520
   TMHMM
   TMhelix (TMhelix)
   533 - 555
   TMHMM
   TMhelix (TMhelix)
   341 - 363
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0007186 G-protein coupled receptor signaling pathway

#### Molecular Function

GO:0004930 G-protein coupled receptor activity
GO:0004965 G-protein coupled GABA receptor activity

#### Cellular Component

GO:0016021 integral component of membrane