Protein

## EMLSAP00000007776

Length
898 amino acids

### Protein family membership

- RNA-induced silencing complex, nuclease component Tudor-SN (IPR016685)

### Domains and repeats

1. Domain
   9 - 159
   - Staphylococcal nuclease (SNase-like), OB-fold (IPR016071)
   178 - 328
   - Staphylococcal nuclease (SNase-like), OB-fold (IPR016071)
   334 - 489
   - Staphylococcal nuclease (SNase-like), OB-fold (IPR016071)
   506 - 649
   - Staphylococcal nuclease (SNase-like), OB-fold (IPR016071)
   731 - 895
   - Staphylococcal nuclease (SNase-like), OB-fold (IPR016071)
2. Domain
   671 - 787
   - Tudor domain (IPR002999)

1 100 200 300 400 500 600 700 800 898

### Detailed signature matches

1. IPR016685
   RNA-induced silencing complex, nuclease component Tudor-SN
   1. PIRSF017179 (RISC-T...)
      1 - 895
      PIRSF
      PIRSF017179 (RISC-Tudor-SN)
2. IPR016071
   Staphylococcal nuclease (SNase-like), OB-fold
   1. PS50830 (TNASE_3)
      512 - 648
      PROSITE profiles
      PS50830 (TNASE_3)
      338 - 488
      PROSITE profiles
      PS50830 (TNASE_3)
      11 - 154
      PROSITE profiles
      PS50830 (TNASE_3)
      181 - 324
      PROSITE profiles
      PS50830 (TNASE_3)
   2. SSF50199 (Staphyloc...)
      334 - 489
      SUPERFAMILY
      SSF50199 (Staphylococcal nuclease)
      506 - 649
      SUPERFAMILY
      SSF50199 (Staphylococcal nuclease)
      9 - 154
      SUPERFAMILY
      SSF50199 (Staphylococcal nuclease)
      178 - 325
      SUPERFAMILY
      SSF50199 (Staphylococcal nuclease)
      731 - 888
      SUPERFAMILY
      SSF50199 (Staphylococcal nuclease)
   3. G3DSA:2.40.50.90
      20 - 159
      GENE3D
      G3DSA:2.40.50.90 (G3DSA:2.40.50.90)
      190 - 328
      GENE3D
      G3DSA:2.40.50.90 (G3DSA:2.40.50.90)
      348 - 489
      GENE3D
      G3DSA:2.40.50.90 (G3DSA:2.40.50.90)
      770 - 895
      GENE3D
      G3DSA:2.40.50.90 (G3DSA:2.40.50.90)
      507 - 649
      GENE3D
      G3DSA:2.40.50.90 (G3DSA:2.40.50.90)
   4. SM00318 (SNc)
      338 - 488
      SMART
      SM00318 (SNc)
      512 - 648
      SMART
      SM00318 (SNc)
      11 - 154
      SMART
      SM00318 (SNc)
      181 - 324
      SMART
      SM00318 (SNc)
   5. PF00565 (SNase)
      42 - 151
      Pfam
      PF00565 (SNase)
      540 - 647
      Pfam
      PF00565 (SNase)
      364 - 485
      Pfam
      PF00565 (SNase)
      214 - 324
      Pfam
      PF00565 (SNase)
3. IPR002999
   Tudor domain
   1. SM00333 (TUDOR)
      718 - 775
      SMART
      SM00333 (TUDOR)
   2. PS50304 (TUDOR)
      719 - 776
      PROSITE profiles
      PS50304 (TUDOR)
   3. PF00567 (TUDOR)
      671 - 787
      Pfam
      PF00567 (TUDOR)

no IPR
Unintegrated signatures

1. G3DSA:2.30.30...
   696 - 769
   GENE3D
   G3DSA:2.30.30.140 (G3DSA:2.30.30.140)
2. PTHR12302 (EBNA2 BI...)
   3 - 895
   PANTHER
   PTHR12302 (EBNA2 BINDING PROTEIN P100)
3. PTHR12302:SF0 (SUBF...)
   3 - 895
   PANTHER
   PTHR12302:SF0 (SUBFAMILY NOT NAMED)
4. SSF63748 (Tudor/PWW...)
   696 - 782
   SUPERFAMILY
   SSF63748 (Tudor/PWWP/MBT)

### GO term prediction

#### Biological Process

GO:0031047 gene silencing by RNA

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0016788 hydrolase activity, acting on ester bonds

#### Cellular Component

GO:0016442 RISC complex