Protein

## EMLSAP00000002213

Length
941 amino acids

### Protein family membership

- Sodium/potassium-transporting P-type ATPase, subfamily IIC (IPR005775)

- Cation-transporting P-type ATPase (IPR001757)

### Domains and repeats

1. Domain
   25 - 99
   - Cation-transporting P-type ATPase, N-terminal (IPR004014)
   348 - 713
   - HAD-like domain (IPR023214)
     - P-type ATPase, cytoplasmic domain N (IPR023299)
   715 - 928
   - P-type ATPase, transmembrane domain (IPR023298)
2. Domain
   35 - 79
   - P-type ATPase, A domain (IPR008250)
   118 - 349
   - P-type ATPase, A domain (IPR008250)
   716 - 925
   - Cation-transporting P-type ATPase, C-terminal (IPR006068)

1 100 200 300 400 500 600 700 800 941

### Detailed signature matches

1. IPR005775
   Sodium/potassium-transporting P-type ATPase, subfamily IIC
   1. TIGR01106
      10 - 715
      UNKNOWN
      TIGR01106 (TIGR01106)
2. IPR001757
   Cation-transporting P-type ATPase
   1. TIGR01494
      119 - 387
      UNKNOWN
      TIGR01494 (TIGR01494)
   2. PR00119 (CATATPASE)
      588 - 598
      PRINTS
      PR00119 (CATATPASE)
      197 - 211
      PRINTS
      PR00119 (CATATPASE)
      694 - 713
      PRINTS
      PR00119 (CATATPASE)
      357 - 371
      PRINTS
      PR00119 (CATATPASE)
      566 - 577
      PRINTS
      PR00119 (CATATPASE)
3. IPR004014
   Cation-transporting P-type ATPase, N-terminal
   1. PF00690 (Cation_ATP...)
      26 - 94
      Pfam
      PF00690 (Cation_ATPase_N)
   2. SM00831 (Cation_ATP...)
      25 - 99
      SMART
      SM00831 (Cation_ATPase_N)
4. IPR008250
   P-type ATPase, A domain
   1. G3DSA:2.70.15...
      35 - 79
      GENE3D
      G3DSA:2.70.150.10 (G3DSA:2.70.150.10)
      150 - 255
      GENE3D
      G3DSA:2.70.150.10 (G3DSA:2.70.150.10)
   2. PF00122 (E1-E2_ATPase)
      118 - 349
      Pfam
      PF00122 (E1-E2_ATPase)
5. IPR023214
   HAD-like domain
   1. PF00702 (Hydrolase)
      354 - 708
      Pfam
      PF00702 (Hydrolase)
   2. G3DSA:3.40.50...
      567 - 713
      GENE3D
      G3DSA:3.40.50.1000 (G3DSA:3.40.50.1000)
   3. SSF56784 (HAD-like)
      561 - 713
      SUPERFAMILY
      SSF56784 (HAD-like)
6. IPR023299
   P-type ATPase, cytoplasmic domain N
   1. SSF81660 (Metal cat...)
      366 - 574
      SUPERFAMILY
      SSF81660 (Metal cation-transporting ATPase, ATP-binding domain N)
   2. G3DSA:3.40.11...
      348 - 566
      GENE3D
      G3DSA:3.40.1110.10 (G3DSA:3.40.1110.10)
7. IPR023298
   P-type ATPase, transmembrane domain
   1. G3DSA:1.20.11...
      715 - 928
      GENE3D
      G3DSA:1.20.1110.10 (G3DSA:1.20.1110.10)
8. IPR006068
   Cation-transporting P-type ATPase, C-terminal
   1. PF00689 (Cation_ATP...)
      716 - 925
      Pfam
      PF00689 (Cation_ATPase_C)
9. IPR018303
   P-type ATPase, phosphorylation site
   1. PS00154 (ATPASE_E1_E2)
      359 - 365
      PROSITE patterns
      PS00154 (ATPASE_E1_E2)

no IPR
Unintegrated signatures

1. G3DSA:4.10.6.10
   117 - 149
   GENE3D
   G3DSA:4.10.6.10 (G3DSA:4.10.6.10)
2. PR00121 (NAKATPASE)
   113 - 133
   PRINTS
   PR00121 (NAKATPASE)
   833 - 853
   PRINTS
   PR00121 (NAKATPASE)
   86 - 100
   PRINTS
   PR00121 (NAKATPASE)
   867 - 891
   PRINTS
   PR00121 (NAKATPASE)
   704 - 725
   PRINTS
   PR00121 (NAKATPASE)
   771 - 791
   PRINTS
   PR00121 (NAKATPASE)
3. PTHR24093 (FAMILY N...)
   8 - 941
   PANTHER
   PTHR24093 (FAMILY NOT NAMED)
4. PTHR24093:SF58 (SUB...)
   8 - 941
   PANTHER
   PTHR24093:SF58 (SUBFAMILY NOT NAMED)
5. SSF81653 (Calcium A...)
   149 - 255
   SUPERFAMILY
   SSF81653 (Calcium ATPase, transduction domain A)
6. SSF81665 (Calcium A...)
   24 - 150
   SUPERFAMILY
   SSF81665 (Calcium ATPase, transmembrane domain M)
   710 - 931
   SUPERFAMILY
   SSF81665 (Calcium ATPase, transmembrane domain M)
   258 - 351
   SUPERFAMILY
   SSF81665 (Calcium ATPase, transmembrane domain M)
7. TMhelix
   273 - 295
   TMHMM
   TMhelix (TMhelix)
   767 - 789
   TMHMM
   TMhelix (TMhelix)
   834 - 856
   TMHMM
   TMhelix (TMhelix)
   305 - 327
   TMHMM
   TMhelix (TMhelix)
   869 - 891
   TMHMM
   TMhelix (TMhelix)
   78 - 100
   TMHMM
   TMhelix (TMhelix)
   901 - 918
   TMHMM
   TMhelix (TMhelix)
   113 - 132
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006754 ATP biosynthetic process
GO:0006812 cation transport
GO:0015672 monovalent inorganic cation transport

#### Molecular Function

GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0015077 monovalent inorganic cation transmembrane transporter activity
GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding

#### Cellular Component

GO:0016021 integral component of membrane