Protein

## EMLSAP00000000012

Length
540 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   9 - 130
   - WGR domain (IPR008893)
   279 - 540
   - Poly(ADP-ribose) polymerase, catalytic domain (IPR012317)
2. Domain
   121 - 289
   - Poly(ADP-ribose) polymerase, regulatory domain (IPR004102)

1 50 100 150 200 250 300 350 400 450 500 540

### Detailed signature matches

1. IPR008893
   WGR domain
   1. PF05406 (WGR)
      40 - 116
      Pfam
      PF05406 (WGR)
   2. G3DSA:2.20.14...
      45 - 114
      GENE3D
      G3DSA:2.20.140.10 (G3DSA:2.20.140.10)
   3. SSF142921 (WGR doma...)
      9 - 130
      SUPERFAMILY
      SSF142921 (WGR domain-like)
   4. SM00773 (WGR)
      41 - 121
      SMART
      SM00773 (WGR)
2. IPR004102
   Poly(ADP-ribose) polymerase, regulatory domain
   1. G3DSA:1.20.14...
      121 - 288
      GENE3D
      G3DSA:1.20.142.10 (G3DSA:1.20.142.10)
   2. PS51060 (PARP_ALPHA_HD)
      158 - 273
      PROSITE profiles
      PS51060 (PARP_ALPHA_HD)
   3. PF02877 (PARP_reg)
      158 - 286
      Pfam
      PF02877 (PARP_reg)
   4. SSF47587 (Domain of...)
      158 - 289
      SUPERFAMILY
      SSF47587 (Domain of poly(ADP-ribose) polymerase)
3. IPR012317
   Poly(ADP-ribose) polymerase, catalytic domain
   1. G3DSA:3.90.22...
      292 - 473
      GENE3D
      G3DSA:3.90.228.10 (G3DSA:3.90.228.10)
   2. PS51059 (PARP_CATAL...)
      279 - 540
      PROSITE profiles
      PS51059 (PARP_CATALYTIC)
   3. PF00644 (PARP)
      288 - 469
      Pfam
      PF00644 (PARP)

no IPR
Unintegrated signatures

1. PTHR15447 (POLY [AD...)
   1 - 474
   PANTHER
   PTHR15447 (POLY [ADP-RIBOSE] POLYMERASE)
2. SSF56399 (ADP-ribos...)
   290 - 472
   SUPERFAMILY
   SSF56399 (ADP-ribosylation)

### GO term prediction

#### Biological Process

GO:0006471 protein ADP-ribosylation

#### Molecular Function

GO:0003950 NAD+ ADP-ribosyltransferase activity

#### Cellular Component

None predicted.