Protein

## EMLSAP00000008555

Length
1,076 amino acids

### Protein family membership

- Short-chain dehydrogenase/reductase SDR (IPR002198)

### Domains and repeats

1. Domain
   31 - 645
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
     - AAA+ ATPase domain (IPR003593)
   788 - 995
   - NAD(P)-binding domain (IPR016040)
2. Domain
   51 - 235
   - Helicase, superfamily 1/2, ATP-binding domain (IPR014001)
     - DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
   251 - 431
   - Helicase, C-terminal (IPR001650)
   451 - 541
   - Helicase-associated domain (IPR007502)
   575 - 678
   - Domain of unknown function DUF1605 (IPR011709)

1 100 200 300 400 500 600 700 800 900 1000 1076

### Detailed signature matches

1. IPR002198
   Short-chain dehydrogenase/reductase SDR
   1. PF00106 (adh_short)
      793 - 919
      Pfam
      PF00106 (adh_short)
2. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      31 - 645
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
3. IPR014001
   Helicase, superfamily 1/2, ATP-binding domain
   1. SM00487 (DEXDc)
      51 - 235
      SMART
      SM00487 (DEXDc)
   2. PS51192 (HELICASE_A...)
      63 - 226
      PROSITE profiles
      PS51192 (HELICASE_ATP_BIND_1)
4. IPR011545
   DNA/RNA helicase, DEAD/DEAH box type, N-terminal
   1. PF00270 (DEAD)
      65 - 209
      Pfam
      PF00270 (DEAD)
5. IPR003593
   AAA+ ATPase domain
   1. SM00382 (AAA)
      68 - 239
      SMART
      SM00382 (AAA)
6. IPR001650
   Helicase, C-terminal
   1. PF00271 (Helicase_C)
      296 - 389
      Pfam
      PF00271 (Helicase_C)
   2. SM00490 (HELICc)
      273 - 390
      SMART
      SM00490 (HELICc)
   3. PS51194 (HELICASE_CTER)
      251 - 431
      PROSITE profiles
      PS51194 (HELICASE_CTER)
7. IPR007502
   Helicase-associated domain
   1. SM00847 (HA2)
      451 - 541
      SMART
      SM00847 (HA2)
   2. PF04408 (HA2)
      452 - 541
      Pfam
      PF04408 (HA2)
8. IPR011709
   Domain of unknown function DUF1605
   1. PF07717 (OB_NTP_bind)
      575 - 678
      Pfam
      PF07717 (OB_NTP_bind)
9. IPR016040
   NAD(P)-binding domain
   1. G3DSA:3.40.50...
      788 - 995
      GENE3D
      G3DSA:3.40.50.720 (G3DSA:3.40.50.720)

no IPR
Unintegrated signatures

1. Coil
   272 - 293
   COILS
   Coil (Coil)
2. G3DSA:3.40.50...
   53 - 209
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   238 - 402
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PTHR18934 (ATP-DEPE...)
   29 - 707
   PANTHER
   PTHR18934 (ATP-DEPENDENT RNA HELICASE)
4. SSF51735 (NAD(P)-bi...)
   788 - 1,030
   SUPERFAMILY
   SSF51735 (NAD(P)-binding Rossmann-fold domains)
5. TMhelix
   755 - 777
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0008152 metabolic process

#### Molecular Function

GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0016491 oxidoreductase activity
GO:0017111 nucleoside-triphosphatase activity

#### Cellular Component

None predicted.