Protein

## EMLSAP00000004739

Length
1,196 amino acids

### Protein family membership

- Formin, protein diaphanous (IPR027658)

### Domains and repeats

1. Domain
   56 - 411
   - Formin, GTPase-binding and FH3 domain (IPR014768)
2. Domain
   58 - 232
   - Formin, GTPase-binding domain (IPR010473)
   237 - 429
   - Formin, FH3 domain (IPR010472)
   1,000 - 1,034
   - Formin, diaphanous autoregulatory (DAD) domain (IPR014767)
     - DRF autoregulatory (IPR010465)
3. Domain
   64 - 414
   - Armadillo-type fold (IPR016024)
   576 - 1,022
   - Formin, FH2 domain (IPR015425)

1 200 400 600 800 1000 1196

### Detailed signature matches

1. IPR027658
   Formin, protein diaphanous
   1. PTHR23213:SF13 (DIA...)
      56 - 1,048
      PANTHER
      PTHR23213:SF13 (DIAPHANOUS)
2. IPR014768
   Formin, GTPase-binding and FH3 domain
   1. PS51232 (GBD_FH3)
      56 - 411
      PROSITE profiles
      PS51232 (GBD_FH3)
3. IPR010473
   Formin, GTPase-binding domain
   1. PF06371 (Drf_GBD)
      58 - 232
      Pfam
      PF06371 (Drf_GBD)
4. IPR016024
   Armadillo-type fold
   1. SSF48371 (ARM repeat)
      64 - 414
      SUPERFAMILY
      SSF48371 (ARM repeat)
5. IPR010472
   Formin, FH3 domain
   1. PF06367 (Drf_FH3)
      237 - 429
      Pfam
      PF06367 (Drf_FH3)
6. IPR015425
   Formin, FH2 domain
   1. SM00498 (FH2)
      576 - 1,022
      SMART
      SM00498 (FH2)
   2. PS51444 (FH2)
      576 - 979
      PROSITE profiles
      PS51444 (FH2)
   3. PF02181 (FH2)
      577 - 954
      Pfam
      PF02181 (FH2)
7. IPR014767
   Formin, diaphanous autoregulatory (DAD) domain
   1. PS51231 (DAD)
      1,000 - 1,034
      PROSITE profiles
      PS51231 (DAD)
8. IPR010465
   DRF autoregulatory
   1. PF06345 (Drf_DAD)
      1,005 - 1,019
      Pfam
      PF06345 (Drf_DAD)

no IPR
Unintegrated signatures

1. Coil
   707 - 728
   COILS
   Coil (Coil)
   866 - 887
   COILS
   Coil (Coil)
   443 - 478
   COILS
   Coil (Coil)
2. PTHR23213 (FORMIN-R...)
   56 - 1,048
   PANTHER
   PTHR23213 (FORMIN-RELATED)
3. SSF101447 (Formin h...)
   652 - 983
   SUPERFAMILY
   SSF101447 (Formin homology 2 domain (FH2 domain))

### GO term prediction

#### Biological Process

GO:0007015 actin filament organization
GO:0007049 cell cycle
GO:0016043 cellular component organization
GO:0030036 actin cytoskeleton organization

#### Molecular Function

GO:0003779 actin binding
GO:0005488 binding
GO:0017048 Rho GTPase binding

#### Cellular Component

None predicted.