Protein

## EMLSAP00000003918

Length
1,623 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   31 - 194
   - Calponin homology domain (IPR001715)
   908 - 1,285
   - Rho GTPase activation protein (IPR008936)
     - Ras GTPase-activating protein (IPR001936)
   1,393 - 1,544
   - RasGAP protein, C-terminal (IPR000593)

1 200 400 600 800 1000 1200 1400 1623

### Detailed signature matches

1. IPR001715
   Calponin homology domain
   1. PF00307 (CH)
      43 - 152
      Pfam
      PF00307 (CH)
   2. G3DSA:1.10.41...
      32 - 186
      GENE3D
      G3DSA:1.10.418.10 (G3DSA:1.10.418.10)
   3. SSF47576 (Calponin-...)
      31 - 194
      SUPERFAMILY
      SSF47576 (Calponin-homology domain, CH-domain)
   4. SM00033 (CH)
      41 - 150
      SMART
      SM00033 (CH)
   5. PS50021 (CH)
      39 - 154
      PROSITE profiles
      PS50021 (CH)
2. IPR008936
   Rho GTPase activation protein
   1. SSF48350 (GTPase ac...)
      1,068 - 1,273
      SUPERFAMILY
      SSF48350 (GTPase activation domain, GAP)
      908 - 1,036
      SUPERFAMILY
      SSF48350 (GTPase activation domain, GAP)
3. IPR001936
   Ras GTPase-activating protein
   1. PF00616 (RasGAP)
      963 - 1,176
      Pfam
      PF00616 (RasGAP)
   2. SM00323 (RasGAP)
      930 - 1,285
      SMART
      SM00323 (RasGAP)
   3. PS50018 (RAS_GTPASE...)
      955 - 1,176
      PROSITE profiles
      PS50018 (RAS_GTPASE_ACTIV_2)
   4. G3DSA:1.10.50...
      1,068 - 1,208
      GENE3D
      G3DSA:1.10.506.10 (G3DSA:1.10.506.10)
      961 - 1,036
      GENE3D
      G3DSA:1.10.506.10 (G3DSA:1.10.506.10)
4. IPR000593
   RasGAP protein, C-terminal
   1. PF03836 (RasGAP_C)
      1,393 - 1,544
      Pfam
      PF03836 (RasGAP_C)
5. IPR000048
   IQ motif, EF-hand binding site
   1. SM00015 (IQ)
      713 - 735
      SMART
      SM00015 (IQ)
   2. PS50096 (IQ)
      714 - 743
      PROSITE profiles
      PS50096 (IQ)
   3. PF00612 (IQ)
      716 - 735
      Pfam
      PF00612 (IQ)

no IPR
Unintegrated signatures

1. Coil
   1,445 - 1,466
   COILS
   Coil (Coil)
2. PTHR14149 (RAS GTPA...)
   21 - 1,623
   PANTHER
   PTHR14149 (RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF)
3. SSF143885 (RGC doma...)
   1,524 - 1,621
   SUPERFAMILY
   SSF143885 (RGC domain-like)

### GO term prediction

#### Biological Process

GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0051056 regulation of small GTPase mediated signal transduction

#### Molecular Function

GO:0005096 GTPase activator activity
GO:0005099 Ras GTPase activator activity
GO:0005515 protein binding

#### Cellular Component

GO:0005622 intracellular