Protein

## EMLSAP00000002993

Length
1,832 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   1 - 488
   - WD40/YVTN repeat-like-containing domain (IPR015943)
     - Sema domain (IPR001627)
   812 - 899
   - Immunoglobulin E-set (IPR014756)
     - IPT domain (IPR002909)
   900 - 988
   - Immunoglobulin E-set (IPR014756)
     - IPT domain (IPR002909)
   1,124 - 1,201
   - IPT domain (IPR002909)
   1,289 - 1,805
   - Plexin, cytoplasmic RasGAP domain (IPR013548)
2. Domain
   820 - 892
   - Immunoglobulin-like fold (IPR013783)
   903 - 990
   - Immunoglobulin-like fold (IPR013783)
   991 - 1,068
   - Immunoglobulin-like fold (IPR013783)
   1,125 - 1,205
   - Immunoglobulin-like fold (IPR013783)
   1,326 - 1,454
   - Rho GTPase activation protein (IPR008936)
   1,624 - 1,775
   - Rho GTPase activation protein (IPR008936)
3. Domain
   986 - 1,081
   - Immunoglobulin E-set (IPR014756)
     - IPT domain (IPR002909)
4. Repeat
   482 - 520
   - Plexin (IPR002165)
5. Repeat
   482 - 532
   - Plexin-like fold (IPR016201)
   628 - 678
   - Plexin-like fold (IPR016201)
   775 - 814
   - Plexin-like fold (IPR016201)

1 200 400 600 800 1000 1200 1400 1600 1832

### Detailed signature matches

1. IPR015943
   WD40/YVTN repeat-like-containing domain
   1. G3DSA:2.130.1...
      29 - 488
      GENE3D
      G3DSA:2.130.10.10 (G3DSA:2.130.10.10)
2. IPR001627
   Sema domain
   1. SSF101912 (Sema domain)
      22 - 443
      SUPERFAMILY
      SSF101912 (Sema domain)
   2. SM00630 (Sema)
      29 - 466
      SMART
      SM00630 (Sema)
   3. PS51004 (SEMA)
      1 - 488
      PROSITE profiles
      PS51004 (SEMA)
   4. PF01403 (Sema)
      32 - 372
      Pfam
      PF01403 (Sema)
3. IPR014756
   Immunoglobulin E-set
   1. SSF81296 (E set dom...)
      812 - 898
      SUPERFAMILY
      SSF81296 (E set domains)
      902 - 988
      SUPERFAMILY
      SSF81296 (E set domains)
      986 - 1,067
      SUPERFAMILY
      SSF81296 (E set domains)
4. IPR002909
   IPT domain
   1. PF01833 (TIG)
      1,124 - 1,201
      Pfam
      PF01833 (TIG)
      989 - 1,071
      Pfam
      PF01833 (TIG)
      902 - 983
      Pfam
      PF01833 (TIG)
      816 - 890
      Pfam
      PF01833 (TIG)
   2. SM00429 (IPT)
      988 - 1,081
      SMART
      SM00429 (IPT)
      815 - 899
      SMART
      SM00429 (IPT)
      900 - 986
      SMART
      SM00429 (IPT)
5. IPR013783
   Immunoglobulin-like fold
   1. G3DSA:2.60.40.10
      820 - 892
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      903 - 990
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      1,125 - 1,205
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      991 - 1,068
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
6. IPR013548
   Plexin, cytoplasmic RasGAP domain
   1. PF08337 (Plexin_cytopl)
      1,289 - 1,805
      Pfam
      PF08337 (Plexin_cytopl)
7. IPR008936
   Rho GTPase activation protein
   1. SSF48350 (GTPase ac...)
      1,326 - 1,454
      SUPERFAMILY
      SSF48350 (GTPase activation domain, GAP)
      1,624 - 1,775
      SUPERFAMILY
      SSF48350 (GTPase activation domain, GAP)
8. IPR002165
   Plexin
   1. PF01437 (PSI)
      482 - 520
      Pfam
      PF01437 (PSI)
9. IPR016201
   Plexin-like fold
   1. SM00423 (PSI)
      775 - 814
      SMART
      SM00423 (PSI)
      628 - 678
      SMART
      SM00423 (PSI)
      482 - 532
      SMART
      SM00423 (PSI)
   2. SSF103575 (Plexin r...)
      482 - 527
      SUPERFAMILY
      SSF103575 (Plexin repeat)

no IPR
Unintegrated signatures

1. Coil
   1,243 - 1,271
   COILS
   Coil (Coil)
2. G3DSA:3.10.20.90
   1,469 - 1,577
   GENE3D
   G3DSA:3.10.20.90 (G3DSA:3.10.20.90)
3. G3DSA:3.30.16...
   489 - 523
   GENE3D
   G3DSA:3.30.1680.10 (G3DSA:3.30.1680.10)
   774 - 819
   GENE3D
   G3DSA:3.30.1680.10 (G3DSA:3.30.1680.10)
4. PTHR22625 (PLEXIN)
   39 - 1,832
   PANTHER
   PTHR22625 (PLEXIN)
5. PTHR22625:SF14 (PLE...)
   39 - 1,832
   PANTHER
   PTHR22625:SF14 (PLEXIN B)
6. SignalP-noTM
   1 - 17
   SignalP euk
   SignalP-noTM (SignalP-noTM)
7. TMhelix
   1,217 - 1,239
   TMHMM
   TMhelix (TMhelix)
   1,360 - 1,377
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0007165 signal transduction
GO:0007275 multicellular organismal development

#### Molecular Function

GO:0004872 receptor activity
GO:0005515 protein binding

#### Cellular Component

GO:0005622 intracellular
GO:0016020 membrane