Protein

## EMLSAP00000005058

Length
627 amino acids

### Protein family membership

- 3'5'-cyclic nucleotide phosphodiesterase (IPR023088)

### Domains and repeats

1. Domain
   189 - 237
   - GAF domain (IPR003018)
   287 - 595
   - HD/PDEase domain (IPR003607)
     - 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain (IPR002073)

1 100 200 300 400 500 627

### Detailed signature matches

1. IPR023088
   3'5'-cyclic nucleotide phosphodiesterase
   1. PR00387 (PDIESTERASE1)
      495 - 508
      PRINTS
      PR00387 (PDIESTERASE1)
      340 - 353
      PRINTS
      PR00387 (PDIESTERASE1)
      415 - 431
      PRINTS
      PR00387 (PDIESTERASE1)
      387 - 402
      PRINTS
      PR00387 (PDIESTERASE1)
      512 - 528
      PRINTS
      PR00387 (PDIESTERASE1)
2. IPR003018
   GAF domain
   1. PF01590 (GAF)
      189 - 237
      Pfam
      PF01590 (GAF)
3. IPR003607
   HD/PDEase domain
   1. SM00471 (HDc)
      342 - 513
      SMART
      SM00471 (HDc)
4. IPR002073
   3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
   1. G3DSA:1.10.13...
      287 - 595
      GENE3D
      G3DSA:1.10.1300.10 (G3DSA:1.10.1300.10)
   2. PF00233 (PDEase_I)
      344 - 583
      Pfam
      PF00233 (PDEase_I)
5. IPR023174
   3'5'-cyclic nucleotide phosphodiesterase, conserved site
   1. PS00126 (PDEASE_I)
      387 - 398
      PROSITE patterns
      PS00126 (PDEASE_I)

no IPR
Unintegrated signatures

1. G3DSA:3.30.45...
   163 - 249
   GENE3D
   G3DSA:3.30.450.40 (G3DSA:3.30.450.40)
2. PTHR11347 (CYCLIC N...)
   190 - 619
   PANTHER
   PTHR11347 (CYCLIC NUCLEOTIDE PHOSPHODIESTERASE)
3. PTHR11347:SF18 (CGM...)
   190 - 619
   PANTHER
   PTHR11347:SF18 (CGMP-DEPENDENT 3,5-CYCLIC PHOSPHODIESTERASE)
4. SSF109604 (HD-domai...)
   284 - 595
   SUPERFAMILY
   SSF109604 (HD-domain/PDEase-like)
5. SSF55781 (GAF domai...)
   186 - 265
   SUPERFAMILY
   SSF55781 (GAF domain-like)

### GO term prediction

#### Biological Process

GO:0007165 signal transduction

#### Molecular Function

GO:0003824 catalytic activity
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 protein binding
GO:0008081 phosphoric diester hydrolase activity

#### Cellular Component

None predicted.