Protein

## EMLSAP00000011965

Length
808 amino acids

### Protein family membership

- Transcription factor STAT (IPR001217)

### Domains and repeats

1. Domain
   97 - 218
   - STAT transcription factor, protein interaction (IPR013799)
   437 - 695
   - p53-like transcription factor, DNA-binding (IPR008967)
     - STAT transcription factor, DNA-binding (IPR013801)
2. Domain
   253 - 442
   - STAT transcription factor, coiled coil (IPR015988)
     - STAT transcription factor, all-alpha (IPR013800)
   443 - 586
   - STAT transcription factor, DNA-binding, subdomain (IPR012345)
   701 - 799
   - SH2 domain (IPR000980)
3. Domain
   587 - 709
   - EF-hand domain pair (IPR011992)

1 100 200 300 400 500 600 700 808

### Detailed signature matches

1. IPR001217
   Transcription factor STAT
   1. PTHR11801 (SIGNAL T...)
      97 - 804
      PANTHER
      PTHR11801 (SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION)
2. IPR013799
   STAT transcription factor, protein interaction
   1. PF02865 (STAT_int)
      98 - 217
      Pfam
      PF02865 (STAT_int)
   2. SM00964 (STAT_int)
      97 - 218
      SMART
      SM00964 (STAT_int)
   3. G3DSA:1.10.53...
      98 - 217
      GENE3D
      G3DSA:1.10.532.10 (G3DSA:1.10.532.10)
   4. SSF48092 (Transcrip...)
      97 - 217
      SUPERFAMILY
      SSF48092 (Transcription factor STAT-4 N-domain)
3. IPR015988
   STAT transcription factor, coiled coil
   1. SSF47655 (STAT)
      253 - 442
      SUPERFAMILY
      SSF47655 (STAT)
4. IPR013800
   STAT transcription factor, all-alpha
   1. G3DSA:1.20.10...
      253 - 442
      GENE3D
      G3DSA:1.20.1050.20 (G3DSA:1.20.1050.20)
   2. PF01017 (STAT_alpha)
      254 - 440
      Pfam
      PF01017 (STAT_alpha)
5. IPR008967
   p53-like transcription factor, DNA-binding
   1. SSF49417 (p53-like ...)
      437 - 695
      SUPERFAMILY
      SSF49417 (p53-like transcription factors)
6. IPR013801
   STAT transcription factor, DNA-binding
   1. PF02864 (STAT_bind)
      442 - 695
      Pfam
      PF02864 (STAT_bind)
7. IPR012345
   STAT transcription factor, DNA-binding, subdomain
   1. G3DSA:2.60.40...
      443 - 586
      GENE3D
      G3DSA:2.60.40.630 (G3DSA:2.60.40.630)
8. IPR011992
   EF-hand domain pair
   1. G3DSA:1.10.23...
      587 - 709
      GENE3D
      G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
9. IPR000980
   SH2 domain
   1. PF00017 (SH2)
      707 - 765
      Pfam
      PF00017 (SH2)
   2. G3DSA:3.30.50...
      710 - 799
      GENE3D
      G3DSA:3.30.505.10 (G3DSA:3.30.505.10)
   3. PS50001 (SH2)
      701 - 799
      PROSITE profiles
      PS50001 (SH2)

no IPR
Unintegrated signatures

1. Coil
   254 - 269
   COILS
   Coil (Coil)
   320 - 341
   COILS
   Coil (Coil)
2. PTHR11801:SF3 (SIGN...)
   97 - 804
   PANTHER
   PTHR11801:SF3 (SIGNAL TRANSDUCER AND TRANSCRIPTION ACTIVATOR)
3. SSF55550 (SH2 domain)
   697 - 799
   SUPERFAMILY
   SSF55550 (SH2 domain)

### GO term prediction

#### Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction

#### Molecular Function

GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
GO:0005509 calcium ion binding
GO:0005515 protein binding

#### Cellular Component

GO:0005634 nucleus