Protein

## EMLSAP00000005181

Length
636 amino acids

### Protein family membership

- XPG/Rad2 endonuclease (IPR006084)

### Domains and repeats

1. Domain
   1 - 96
   - XPG N-terminal (IPR006085)
   116 - 200
   - XPG-I domain (IPR006086)
2. Domain
   185 - 229
   - 5'-3' exonuclease, C-terminal domain (IPR020045)
   296 - 363
   - 5'-3' exonuclease, C-terminal domain (IPR020045)

1 100 200 300 400 500 636

### Detailed signature matches

1. IPR006084
   XPG/Rad2 endonuclease
   1. PTHR11081 (XP-G/RAD...)
      2 - 620
      PANTHER
      PTHR11081 (XP-G/RAD2 DNA REPAIR ENDONUCLEASE FAMILY)
   2. PR00853 (XPGRADSUPER)
      190 - 205
      PRINTS
      PR00853 (XPGRADSUPER)
      115 - 132
      PRINTS
      PR00853 (XPGRADSUPER)
      24 - 38
      PRINTS
      PR00853 (XPGRADSUPER)
      67 - 86
      PRINTS
      PR00853 (XPGRADSUPER)
2. IPR006085
   XPG N-terminal
   1. PF00752 (XPG_N)
      1 - 88
      Pfam
      PF00752 (XPG_N)
   2. SM00485 (XPGN)
      1 - 96
      SMART
      SM00485 (XPGN)
3. IPR006086
   XPG-I domain
   1. PF00867 (XPG_I)
      117 - 200
      Pfam
      PF00867 (XPG_I)
   2. SM00484 (XPGI)
      116 - 185
      SMART
      SM00484 (XPGI)
4. IPR020045
   5'-3' exonuclease, C-terminal domain
   1. SSF47807 (5' to 3' ...)
      296 - 363
      SUPERFAMILY
      SSF47807 (5' to 3' exonuclease, C-terminal subdomain)
      185 - 229
      SUPERFAMILY
      SSF47807 (5' to 3' exonuclease, C-terminal subdomain)
5. IPR008918
   Helix-hairpin-helix motif, class 2
   1. SM00279 (HhH2)
      187 - 221
      SMART
      SM00279 (HhH2)

no IPR
Unintegrated signatures

1. G3DSA:1.10.15...
   185 - 233
   GENE3D
   G3DSA:1.10.150.20 (G3DSA:1.10.150.20)
2. G3DSA:3.40.50...
   1 - 183
   GENE3D
   G3DSA:3.40.50.1010 (G3DSA:3.40.50.1010)
3. PTHR11081:SF5 (XP-G...)
   2 - 620
   PANTHER
   PTHR11081:SF5 (XP-G/RAD2 DNA REPAIR ENDONUCLEASE FAMILY MEMBER)
4. SSF88723 (PIN domai...)
   2 - 200
   SUPERFAMILY
   SSF88723 (PIN domain-like)

### GO term prediction

#### Biological Process

GO:0006281 DNA repair

#### Molecular Function

GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity

#### Cellular Component

None predicted.