Protein

## EMLSAP00000004923

Length
1,113 amino acids

### Protein family membership

- Urocanase (IPR023637)

### Domains and repeats

1. Domain
   172 - 267
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   268 - 511
   - Aldehyde dehydrogenase, N-terminal (IPR016162)
   512 - 690
   - Aldehyde dehydrogenase, C-terminal (IPR016163)
2. Domain
   178 - 256
   - Sulfotransferase domain (IPR000863)
   268 - 691
   - Aldehyde/histidinol dehydrogenase (IPR016161)
     - Aldehyde dehydrogenase domain (IPR015590)

1 200 400 600 800 1000 1113

### Detailed signature matches

1. IPR023637
   Urocanase
   1. SSF111326 (Urocanase)
      771 - 1,111
      SUPERFAMILY
      SSF111326 (Urocanase)
   2. PF01175 (Urocanase)
      779 - 831
      Pfam
      PF01175 (Urocanase)
      832 - 1,111
      Pfam
      PF01175 (Urocanase)
2. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      172 - 267
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
3. IPR000863
   Sulfotransferase domain
   1. PF00685 (Sulfotrans...)
      178 - 256
      Pfam
      PF00685 (Sulfotransfer_1)
4. IPR016162
   Aldehyde dehydrogenase, N-terminal
   1. G3DSA:3.40.60...
      268 - 511
      GENE3D
      G3DSA:3.40.605.10 (G3DSA:3.40.605.10)
5. IPR016161
   Aldehyde/histidinol dehydrogenase
   1. SSF53720 (ALDH-like)
      268 - 691
      SUPERFAMILY
      SSF53720 (ALDH-like)
6. IPR015590
   Aldehyde dehydrogenase domain
   1. PF00171 (Aldedh)
      269 - 685
      Pfam
      PF00171 (Aldedh)
7. IPR016163
   Aldehyde dehydrogenase, C-terminal
   1. G3DSA:3.40.30...
      512 - 690
      GENE3D
      G3DSA:3.40.309.10 (G3DSA:3.40.309.10)
8. IPR016160
   Aldehyde dehydrogenase, conserved site
   1. PS00687 (ALDEHYDE_D...)
      497 - 504
      PROSITE patterns
      PS00687 (ALDEHYDE_DEHYDR_GLU)

no IPR
Unintegrated signatures

1. G3DSA:3.40.17...
   832 - 884
   GENE3D
   G3DSA:3.40.1770.10 (G3DSA:3.40.1770.10)
   774 - 831
   GENE3D
   G3DSA:3.40.1770.10 (G3DSA:3.40.1770.10)
2. G3DSA:3.40.50...
   885 - 1,109
   GENE3D
   G3DSA:3.40.50.10730 (G3DSA:3.40.50.10730)
3. G3DSA:3.40.50...
   167 - 267
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
4. PTHR11699 (ALDEHYDE...)
   267 - 687
   PANTHER
   PTHR11699 (ALDEHYDE DEHYDROGENASE-RELATED)
5. PTHR11699:SF26 (ALD...)
   267 - 687
   PANTHER
   PTHR11699:SF26 (ALDEHYDE DEHYDROGENASE 7)

### GO term prediction

#### Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0008146 sulfotransferase activity
GO:0016153 urocanate hydratase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

#### Cellular Component

None predicted.