Protein

## EMLSAP00000011758

Length
546 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   102 - 194
   - Winged helix-turn-helix DNA-binding domain (IPR011991)
     - DEP domain (IPR000591)
   323 - 384
   - G-protein gamma-like domain (IPR015898)
   388 - 514
   - Regulator of G protein signalling superfamily (IPR016137)
     - Regulator of G protein signalling domain (IPR000342)
2. Domain
   388 - 425
   - Regulator of G-protein signalling, domain 1 (IPR024066)

1 50 100 150 200 250 300 350 400 450 500 546

### Detailed signature matches

1. IPR011991
   Winged helix-turn-helix DNA-binding domain
   1. G3DSA:1.10.10.10
      102 - 194
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
2. IPR000591
   DEP domain
   1. SM00049 (DEP)
      116 - 192
      SMART
      SM00049 (DEP)
   2. PF00610 (DEP)
      119 - 190
      Pfam
      PF00610 (DEP)
   3. PS50186 (DEP)
      116 - 192
      PROSITE profiles
      PS50186 (DEP)
3. IPR015898
   G-protein gamma-like domain
   1. SSF48670 (Transduci...)
      325 - 377
      SUPERFAMILY
      SSF48670 (Transducin (heterotrimeric G protein), gamma chain)
   2. G3DSA:4.10.26...
      325 - 382
      GENE3D
      G3DSA:4.10.260.10 (G3DSA:4.10.260.10)
   3. SM00224 (GGL)
      323 - 384
      SMART
      SM00224 (GGL)
4. IPR024066
   Regulator of G-protein signalling, domain 1
   1. G3DSA:1.10.19...
      388 - 425
      GENE3D
      G3DSA:1.10.196.10 (G3DSA:1.10.196.10)
5. IPR016137
   Regulator of G protein signalling superfamily
   1. SSF48097 (Regulator...)
      388 - 514
      SUPERFAMILY
      SSF48097 (Regulator of G-protein signaling, RGS)
   2. PS50132 (RGS)
      398 - 513
      PROSITE profiles
      PS50132 (RGS)
   3. SM00315 (RGS)
      398 - 513
      SMART
      SM00315 (RGS)
6. IPR000342
   Regulator of G protein signalling domain
   1. PF00615 (RGS)
      401 - 512
      Pfam
      PF00615 (RGS)
   2. PR01301 (RGSPROTEIN)
      487 - 506
      PRINTS
      PR01301 (RGSPROTEIN)
      445 - 468
      PRINTS
      PR01301 (RGSPROTEIN)
      417 - 435
      PRINTS
      PR01301 (RGSPROTEIN)
      395 - 416
      PRINTS
      PR01301 (RGSPROTEIN)

no IPR
Unintegrated signatures

1. G3DSA:1.10.16...
   426 - 498
   GENE3D
   G3DSA:1.10.167.10 (G3DSA:1.10.167.10)
2. PTHR10845 (REGULATO...)
   43 - 521
   PANTHER
   PTHR10845 (REGULATOR OF G PROTEIN SIGNALING)
3. PTHR10845:SF25 (REG...)
   43 - 521
   PANTHER
   PTHR10845:SF25 (REGULATOR OF G PROTEIN SIGNALING)
4. SSF46785 ("Winged h...)
   97 - 200
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)

### GO term prediction

#### Biological Process

GO:0007186 G-protein coupled receptor signaling pathway
GO:0035556 intracellular signal transduction
GO:0038032 termination of G-protein coupled receptor signaling pathway

#### Molecular Function

GO:0004871 signal transducer activity

#### Cellular Component

GO:0005834 heterotrimeric G-protein complex