Protein

## EMLSAP00000002955

Length
269 amino acids

### Protein family membership

- Neurotransmitter-gated ion-channel (IPR006201)

### Domains and repeats

1. Domain
   28 - 232
   - Neurotransmitter-gated ion-channel ligand-binding (IPR006202)
2. Domain
   232 - 268
   - Neurotransmitter-gated ion-channel transmembrane domain (IPR006029)

1 50 100 150 200 269

### Detailed signature matches

1. IPR006201
   Neurotransmitter-gated ion-channel
   1. PTHR18945 (NEUROTRA...)
      1 - 268
      PANTHER
      PTHR18945 (NEUROTRANSMITTER GATED ION CHANNEL)
   2. PR00252 (NRIONCHANNEL)
      226 - 238
      PRINTS
      PR00252 (NRIONCHANNEL)
      76 - 92
      PRINTS
      PR00252 (NRIONCHANNEL)
2. IPR006202
   Neurotransmitter-gated ion-channel ligand-binding
   1. PF02931 (Neur_chan_LBD)
      30 - 232
      Pfam
      PF02931 (Neur_chan_LBD)
   2. SSF63712 (Nicotinic...)
      28 - 231
      SUPERFAMILY
      SSF63712 (Nicotinic receptor ligand binding domain-like)
   3. G3DSA:2.70.17...
      30 - 231
      GENE3D
      G3DSA:2.70.170.10 (G3DSA:2.70.170.10)
3. IPR006029
   Neurotransmitter-gated ion-channel transmembrane domain
   1. SSF90112 (Neurotran...)
      232 - 265
      SUPERFAMILY
      SSF90112 (Neurotransmitter-gated ion-channel transmembrane pore)
   2. PF02932 (Neur_chan_...)
      239 - 268
      Pfam
      PF02932 (Neur_chan_memb)
4. IPR027361
   Nicotinic acetylcholine-gated receptor, transmembrane domain
   1. G3DSA:1.20.12...
      232 - 268
      GENE3D
      G3DSA:1.20.120.370 (G3DSA:1.20.120.370)
5. IPR018000
   Neurotransmitter-gated ion-channel, conserved site
   1. PS00236 (NEUROTR_IO...)
      141 - 155
      PROSITE patterns
      PS00236 (NEUROTR_ION_CHANNEL)

no IPR
Unintegrated signatures

1. PTHR18945:SF88 (ACE...)
   1 - 268
   PANTHER
   PTHR18945:SF88 (ACETYLCHOLINE RECEPTOR PROTEIN ALPHA, INVERTEBRATE)
2. SignalP-noTM
   1 - 24
   SignalP euk
   SignalP-noTM (SignalP-noTM)
3. TMhelix
   234 - 256
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006810 transport
GO:0006811 ion transport

#### Molecular Function

GO:0005230 extracellular ligand-gated ion channel activity

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane