Protein

## EMLSAP00000008633

Length
734 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   44 - 155
   - Peptidase M12B, propeptide (IPR002870)
   243 - 459
   - Metallopeptidase, catalytic domain (IPR024079)
   473 - 562
   - Blood coagulation inhibitor, Disintegrin (IPR001762)
2. Domain
   244 - 467
   - Peptidase M12B, ADAM/reprolysin (IPR001590)

1 100 200 300 400 500 600 734

### Detailed signature matches

1. IPR002870
   Peptidase M12B, propeptide
   1. PF01562 (Pep_M12B_p...)
      44 - 155
      Pfam
      PF01562 (Pep_M12B_propep)
2. IPR024079
   Metallopeptidase, catalytic domain
   1. G3DSA:3.40.39...
      243 - 459
      GENE3D
      G3DSA:3.40.390.10 (G3DSA:3.40.390.10)
3. IPR001590
   Peptidase M12B, ADAM/reprolysin
   1. PS50215 (ADAM_MEPRO)
      244 - 467
      PROSITE profiles
      PS50215 (ADAM_MEPRO)
4. IPR001762
   Blood coagulation inhibitor, Disintegrin
   1. SSF57552 (Blood coa...)
      482 - 558
      SUPERFAMILY
      SSF57552 (Blood coagulation inhibitor (disintegrin))
   2. PF00200 (Disintegrin)
      482 - 557
      Pfam
      PF00200 (Disintegrin)
   3. SM00050 (DISIN)
      482 - 560
      SMART
      SM00050 (DISIN)
   4. PS50214 (DISINTEGRIN_2)
      473 - 562
      PROSITE profiles
      PS50214 (DISINTEGRIN_2)
   5. G3DSA:4.10.70.10
      498 - 557
      GENE3D
      G3DSA:4.10.70.10 (G3DSA:4.10.70.10)

no IPR
Unintegrated signatures

1. PF13688 (Reprolysin_5)
   243 - 454
   Pfam
   PF13688 (Reprolysin_5)
2. PTHR11905 (ADAM (A ...)
   1 - 691
   PANTHER
   PTHR11905 (ADAM (A DISINTEGRIN AND METALLOPROTEASE DOMAIN))
3. PTHR11905:SF3 (ADAM 17)
   1 - 691
   PANTHER
   PTHR11905:SF3 (ADAM 17)
4. SSF55486 (Metallopr...)
   242 - 470
   SUPERFAMILY
   SSF55486 (Metalloproteases ("zincins"), catalytic domain)
5. SignalP-noTM
   1 - 23
   SignalP euk
   SignalP-noTM (SignalP-noTM)
6. TMhelix
   666 - 688
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis

#### Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding

#### Cellular Component

None predicted.