Protein

## EMLSAP00000011461

Length
1,313 amino acids

### Protein family membership

- Aldehyde oxidase/xanthine dehydrogenase (IPR016208)

### Domains and repeats

1. Domain
   9 - 94
   - Beta-grasp domain (IPR012675)
     - 2Fe-2S ferredoxin-type domain (IPR001041)
   199 - 406
   - FAD-binding, type 2 (IPR016166)
     - Molybdopterin dehydrogenase, FAD-binding (IPR002346)
   552 - 694
   - Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead (IPR000674)
2. Domain
   90 - 176
   - [2Fe-2S]-binding (IPR002888)
   226 - 271
   - FAD-binding, type 2, subdomain 1 (IPR016167)
   278 - 403
   - CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 (IPR016169)
   407 - 516
   - CO dehydrogenase flavoprotein, C-terminal (IPR005107)
   677 - 1,291
   - Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding (IPR008274)

1 200 400 600 800 1000 1200 1313

### Detailed signature matches

1. IPR016208
   Aldehyde oxidase/xanthine dehydrogenase
   1. PIRSF000127 (Xanthi...)
      3 - 1,313
      PIRSF
      PIRSF000127 (Xanthine_dh)
2. IPR012675
   Beta-grasp domain
   1. G3DSA:3.10.20.30
      9 - 90
      GENE3D
      G3DSA:3.10.20.30 (G3DSA:3.10.20.30)
3. IPR001041
   2Fe-2S ferredoxin-type domain
   1. SSF54292 (2Fe-2S fe...)
      11 - 94
      SUPERFAMILY
      SSF54292 (2Fe-2S ferredoxin-like)
   2. PS51085 (2FE2S_FER_2)
      9 - 94
      PROSITE profiles
      PS51085 (2FE2S_FER_2)
   3. PF00111 (Fer2)
      15 - 79
      Pfam
      PF00111 (Fer2)
4. IPR002888
   [2Fe-2S]-binding
   1. SSF47741 (CO dehydr...)
      102 - 175
      SUPERFAMILY
      SSF47741 (CO dehydrogenase ISP C-domain like)
   2. G3DSA:1.10.15...
      91 - 176
      GENE3D
      G3DSA:1.10.150.120 (G3DSA:1.10.150.120)
   3. PF01799 (Fer2_2)
      90 - 164
      Pfam
      PF01799 (Fer2_2)
5. IPR016166
   FAD-binding, type 2
   1. PS51387 (FAD_PCMH)
      227 - 406
      PROSITE profiles
      PS51387 (FAD_PCMH)
   2. SSF56176 (FAD-bindi...)
      199 - 403
      SUPERFAMILY
      SSF56176 (FAD-binding/transporter-associated domain-like)
6. IPR016167
   FAD-binding, type 2, subdomain 1
   1. G3DSA:3.30.43.10
      226 - 271
      GENE3D
      G3DSA:3.30.43.10 (G3DSA:3.30.43.10)
7. IPR002346
   Molybdopterin dehydrogenase, FAD-binding
   1. PF00941 (FAD_binding_5)
      233 - 403
      Pfam
      PF00941 (FAD_binding_5)
8. IPR016169
   CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
   1. G3DSA:3.30.46...
      278 - 403
      GENE3D
      G3DSA:3.30.465.10 (G3DSA:3.30.465.10)
9. IPR005107
   CO dehydrogenase flavoprotein, C-terminal
   1. SSF55447 (CO dehydr...)
      407 - 516
      SUPERFAMILY
      SSF55447 (CO dehydrogenase flavoprotein C-terminal domain-like)
   2. PF03450 (CO_deh_flav_C)
      412 - 514
      Pfam
      PF03450 (CO_deh_flav_C)
   3. SM01092 (CO_deh_flav_C)
      411 - 515
      SMART
      SM01092 (CO_deh_flav_C)
10. IPR000674
    Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
    1. SM01008 (Ald_Xan_dh_C)
       567 - 676
       SMART
       SM01008 (Ald_Xan_dh_C)
    2. SSF54665 (CO dehydr...)
       552 - 694
       SUPERFAMILY
       SSF54665 (CO dehydrogenase molybdoprotein N-domain-like)
    3. G3DSA:3.90.11...
       552 - 675
       GENE3D
       G3DSA:3.90.1170.50 (G3DSA:3.90.1170.50)
    4. PF01315 (Ald_Xan_dh_C)
       567 - 675
       Pfam
       PF01315 (Ald_Xan_dh_C)
11. IPR008274
    Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding
    1. PF02738 (Ald_Xan_dh_C2)
       688 - 1,218
       Pfam
       PF02738 (Ald_Xan_dh_C2)
    2. G3DSA:3.30.36...
       995 - 1,143
       GENE3D
       G3DSA:3.30.365.10 (G3DSA:3.30.365.10)
       820 - 895
       GENE3D
       G3DSA:3.30.365.10 (G3DSA:3.30.365.10)
       677 - 712
       GENE3D
       G3DSA:3.30.365.10 (G3DSA:3.30.365.10)
       713 - 818
       GENE3D
       G3DSA:3.30.365.10 (G3DSA:3.30.365.10)
       896 - 994
       GENE3D
       G3DSA:3.30.365.10 (G3DSA:3.30.365.10)
       1,144 - 1,290
       GENE3D
       G3DSA:3.30.365.10 (G3DSA:3.30.365.10)
    3. SSF56003 (Molybdenu...)
       677 - 1,291
       SUPERFAMILY
       SSF56003 (Molybdenum cofactor-binding domain)
12. IPR006058
    2Fe-2S ferredoxin, iron-sulphur binding site
    1. PS00197 (2FE2S_FER_1)
       48 - 56
       PROSITE patterns
       PS00197 (2FE2S_FER_1)

no IPR
Unintegrated signatures

1. G3DSA:3.30.39...
   406 - 517
   GENE3D
   G3DSA:3.30.390.50 (G3DSA:3.30.390.50)
2. PTHR11908 (XANTHINE...)
   5 - 1,298
   PANTHER
   PTHR11908 (XANTHINE DEHYDROGENASE)
3. PTHR11908:SF32 (SUB...)
   5 - 1,298
   PANTHER
   PTHR11908:SF32 (SUBFAMILY NOT NAMED)

### GO term prediction

#### Biological Process

GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0003824 catalytic activity
GO:0005506 iron ion binding
GO:0008762 UDP-N-acetylmuramate dehydrogenase activity
GO:0009055 electron carrier activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0046872 metal ion binding
GO:0050660 flavin adenine dinucleotide binding
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding

#### Cellular Component

None predicted.