Protein

## EMLSAP00000002423

Length
837 amino acids

### Protein family membership

- Mini-chromosome maintenance, DNA-dependent ATPase (IPR001208)
  - Mini-chromosome maintenance complex protein 4 (IPR008047)

### Domains and repeats

1. Domain
   129 - 254
   - MCM N-terminal domain (IPR027925)
   265 - 313
   - Rubredoxin-type fold (IPR004039)
2. Domain
   156 - 390
   - Nucleic acid-binding, OB-fold (IPR012340)
   439 - 753
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
     - AAA+ ATPase domain (IPR003593)

1 100 200 300 400 500 600 700 837

### Detailed signature matches

1. IPR001208
   Mini-chromosome maintenance, DNA-dependent ATPase
   1. PR01657 (MCMFAMILY)
      472 - 487
      PRINTS
      PR01657 (MCMFAMILY)
      560 - 573
      PRINTS
      PR01657 (MCMFAMILY)
      584 - 596
      PRINTS
      PR01657 (MCMFAMILY)
      611 - 619
      PRINTS
      PR01657 (MCMFAMILY)
      532 - 546
      PRINTS
      PR01657 (MCMFAMILY)
   2. PF00493 (MCM)
      419 - 740
      Pfam
      PF00493 (MCM)
   3. PS50051 (MCM_2)
      429 - 637
      PROSITE profiles
      PS50051 (MCM_2)
   4. SM00350 (MCM)
      234 - 741
      SMART
      SM00350 (MCM)
2. IPR008047
   Mini-chromosome maintenance complex protein 4
   1. PR01660 (MCMPROTEIN4)
      260 - 273
      PRINTS
      PR01660 (MCMPROTEIN4)
      308 - 320
      PRINTS
      PR01660 (MCMPROTEIN4)
      445 - 456
      PRINTS
      PR01660 (MCMPROTEIN4)
      593 - 610
      PRINTS
      PR01660 (MCMPROTEIN4)
      741 - 750
      PRINTS
      PR01660 (MCMPROTEIN4)
3. IPR027925
   MCM N-terminal domain
   1. PF14551 (MCM_N)
      129 - 254
      Pfam
      PF14551 (MCM_N)
4. IPR012340
   Nucleic acid-binding, OB-fold
   1. SSF50249 (Nucleic a...)
      156 - 385
      SUPERFAMILY
      SSF50249 (Nucleic acid-binding proteins)
   2. G3DSA:2.40.50...
      237 - 264
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
      315 - 390
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
5. IPR004039
   Rubredoxin-type fold
   1. G3DSA:2.20.28.10
      265 - 313
      GENE3D
      G3DSA:2.20.28.10 (G3DSA:2.20.28.10)
6. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      439 - 753
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
7. IPR003593
   AAA+ ATPase domain
   1. SM00382 (AAA)
      473 - 625
      SMART
      SM00382 (AAA)
8. IPR018525
   Mini-chromosome maintenance, conserved site
   1. PS00847 (MCM_1)
      540 - 548
      PROSITE patterns
      PS00847 (MCM_1)

no IPR
Unintegrated signatures

1. G3DSA:3.30.16...
   123 - 223
   GENE3D
   G3DSA:3.30.1640.10 (G3DSA:3.30.1640.10)
2. G3DSA:3.40.50...
   439 - 620
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PTHR11630 (DNA REPL...)
   66 - 834
   PANTHER
   PTHR11630 (DNA REPLICATION LICENSING FACTOR)
4. PTHR11630:SF45 (DNA...)
   66 - 834
   PANTHER
   PTHR11630:SF45 (DNA REPLICATION LICENSING FACTOR MCM4)

### GO term prediction

#### Biological Process

GO:0006260 DNA replication
GO:0006270 DNA replication initiation

#### Molecular Function

GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
GO:0017111 nucleoside-triphosphatase activity

#### Cellular Component

GO:0042555 MCM complex