Protein

## EMLSAP00000000936

Length
3,022 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   110 - 261
   - Cadherin-like (IPR015919)
     - Cadherin (IPR002126)
   896 - 2,061
   - Cadherin-like (IPR015919)
     - Cadherin (IPR002126)
   2,251 - 2,480
   - Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
     - Laminin G domain (IPR001791)
   2,504 - 2,710
   - Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
     - Laminin G domain (IPR001791)
2. Domain
   321 - 897
   - Cadherin-like (IPR015919)
     - Cadherin (IPR002126)
   2,229 - 2,265
   - EGF-like calcium-binding domain (IPR001881)
   2,712 - 2,752
   - EGF-like calcium-binding domain (IPR001881)
   2,753 - 2,791
   - EGF-like calcium-binding domain (IPR001881)
   2,962 - 3,017
   - Catenin binding domain (IPR027397)
3. Domain
   2,229 - 2,265
   - Epidermal growth factor-like domain (IPR000742)
   2,476 - 2,516
   - Epidermal growth factor-like domain (IPR000742)
   2,715 - 2,752
   - Epidermal growth factor-like domain (IPR000742)
   2,753 - 2,791
   - Epidermal growth factor-like domain (IPR000742)
   2,831 - 2,866
   - Epidermal growth factor-like domain (IPR000742)
   2,902 - 3,017
   - Cadherin, cytoplasmic domain (IPR000233)
4. Domain
   2,250 - 2,475
   - Concanavalin A-like lectin/glucanases superfamily (IPR008985)
   2,503 - 2,711
   - Concanavalin A-like lectin/glucanases superfamily (IPR008985)

1 500 1000 1500 2000 2500 3022

### Detailed signature matches

1. IPR015919
   Cadherin-like
   1. SSF49313 (Cadherin-...)
      520 - 629
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,962 - 2,061
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      725 - 846
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      405 - 500
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,734 - 1,863
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,839 - 1,975
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,393 - 1,515
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      110 - 211
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,293 - 1,399
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      898 - 1,019
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      834 - 890
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,057 - 1,188
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      617 - 729
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      213 - 260
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      353 - 409
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,178 - 1,270
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,621 - 1,735
      SUPERFAMILY
      SSF49313 (Cadherin-like)
      1,503 - 1,634
      SUPERFAMILY
      SSF49313 (Cadherin-like)
2. IPR002126
   Cadherin
   1. SM00112 (CA)
      1,768 - 1,849
      SMART
      SM00112 (CA)
      1,423 - 1,513
      SMART
      SM00112 (CA)
      1,652 - 1,744
      SMART
      SM00112 (CA)
      147 - 217
      SMART
      SM00112 (CA)
      441 - 521
      SMART
      SM00112 (CA)
      1,871 - 1,966
      SMART
      SM00112 (CA)
      1,092 - 1,183
      SMART
      SM00112 (CA)
      544 - 627
      SMART
      SM00112 (CA)
      753 - 844
      SMART
      SM00112 (CA)
      1,537 - 1,625
      SMART
      SM00112 (CA)
      652 - 729
      SMART
      SM00112 (CA)
      321 - 415
      SMART
      SM00112 (CA)
      1,206 - 1,297
      SMART
      SM00112 (CA)
      917 - 998
      SMART
      SM00112 (CA)
      1,321 - 1,397
      SMART
      SM00112 (CA)
   2. PF00028 (Cadherin)
      1,521 - 1,617
      Pfam
      PF00028 (Cadherin)
      638 - 719
      Pfam
      PF00028 (Cadherin)
      1,192 - 1,269
      Pfam
      PF00028 (Cadherin)
      739 - 810
      Pfam
      PF00028 (Cadherin)
      1,077 - 1,174
      Pfam
      PF00028 (Cadherin)
      902 - 990
      Pfam
      PF00028 (Cadherin)
      1,413 - 1,505
      Pfam
      PF00028 (Cadherin)
      1,304 - 1,389
      Pfam
      PF00028 (Cadherin)
      1,755 - 1,841
      Pfam
      PF00028 (Cadherin)
   3. PR00205 (CADHERIN)
      1,164 - 1,183
      PRINTS
      PR00205 (CADHERIN)
      568 - 587
      PRINTS
      PR00205 (CADHERIN)
      1,497 - 1,514
      PRINTS
      PR00205 (CADHERIN)
      731 - 760
      PRINTS
      PR00205 (CADHERIN)
      1,350 - 1,376
      PRINTS
      PR00205 (CADHERIN)
      799 - 811
      PRINTS
      PR00205 (CADHERIN)
      1,297 - 1,310
      PRINTS
      PR00205 (CADHERIN)
   4. G3DSA:2.60.40.60
      1,849 - 1,960
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      1,625 - 1,738
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      1,739 - 1,848
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      1,512 - 1,624
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      898 - 1,002
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      350 - 413
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      1,017 - 1,067
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      1,191 - 1,295
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      217 - 261
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      414 - 500
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      728 - 842
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      1,296 - 1,395
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      1,396 - 1,511
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      114 - 216
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      626 - 727
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      1,068 - 1,187
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      521 - 625
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
      843 - 892
      GENE3D
      G3DSA:2.60.40.60 (G3DSA:2.60.40.60)
   5. PS50268 (CADHERIN_2)
      1,747 - 1,851
      PROSITE profiles
      PS50268 (CADHERIN_2)
      732 - 846
      PROSITE profiles
      PS50268 (CADHERIN_2)
      1,300 - 1,399
      PROSITE profiles
      PS50268 (CADHERIN_2)
      525 - 629
      PROSITE profiles
      PS50268 (CADHERIN_2)
      1,649 - 1,746
      PROSITE profiles
      PS50268 (CADHERIN_2)
      848 - 897
      PROSITE profiles
      PS50268 (CADHERIN_2)
      420 - 524
      PROSITE profiles
      PS50268 (CADHERIN_2)
      1,010 - 1,069
      PROSITE profiles
      PS50268 (CADHERIN_2)
      1,185 - 1,299
      PROSITE profiles
      PS50268 (CADHERIN_2)
      1,079 - 1,185
      PROSITE profiles
      PS50268 (CADHERIN_2)
      631 - 731
      PROSITE profiles
      PS50268 (CADHERIN_2)
      896 - 1,000
      PROSITE profiles
      PS50268 (CADHERIN_2)
      1,851 - 1,970
      PROSITE profiles
      PS50268 (CADHERIN_2)
      1,400 - 1,515
      PROSITE profiles
      PS50268 (CADHERIN_2)
      324 - 417
      PROSITE profiles
      PS50268 (CADHERIN_2)
      113 - 219
      PROSITE profiles
      PS50268 (CADHERIN_2)
      1,516 - 1,627
      PROSITE profiles
      PS50268 (CADHERIN_2)
3. IPR000742
   Epidermal growth factor-like domain
   1. PF00008 (EGF)
      2,757 - 2,789
      Pfam
      PF00008 (EGF)
   2. PS50026 (EGF_3)
      2,476 - 2,516
      PROSITE profiles
      PS50026 (EGF_3)
      2,753 - 2,791
      PROSITE profiles
      PS50026 (EGF_3)
      2,229 - 2,265
      PROSITE profiles
      PS50026 (EGF_3)
      2,834 - 2,866
      PROSITE profiles
      PS50026 (EGF_3)
   3. SM00181 (EGF)
      2,831 - 2,866
      SMART
      SM00181 (EGF)
      2,756 - 2,791
      SMART
      SM00181 (EGF)
      2,232 - 2,265
      SMART
      SM00181 (EGF)
      2,479 - 2,516
      SMART
      SM00181 (EGF)
      2,715 - 2,752
      SMART
      SM00181 (EGF)
4. IPR001881
   EGF-like calcium-binding domain
   1. SM00179 (EGF_CA)
      2,712 - 2,752
      SMART
      SM00179 (EGF_CA)
      2,229 - 2,265
      SMART
      SM00179 (EGF_CA)
      2,753 - 2,791
      SMART
      SM00179 (EGF_CA)
5. IPR008985
   Concanavalin A-like lectin/glucanases superfamily
   1. SSF49899 (Concanava...)
      2,503 - 2,711
      SUPERFAMILY
      SSF49899 (Concanavalin A-like lectins/glucanases)
      2,250 - 2,475
      SUPERFAMILY
      SSF49899 (Concanavalin A-like lectins/glucanases)
6. IPR013320
   Concanavalin A-like lectin/glucanase, subgroup
   1. G3DSA:2.60.12...
      2,504 - 2,696
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
      2,251 - 2,466
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
7. IPR001791
   Laminin G domain
   1. SM00282 (LamG)
      2,541 - 2,684
      SMART
      SM00282 (LamG)
      2,286 - 2,456
      SMART
      SM00282 (LamG)
   2. PF02210 (Laminin_G_2)
      2,294 - 2,455
      Pfam
      PF02210 (Laminin_G_2)
      2,549 - 2,683
      Pfam
      PF02210 (Laminin_G_2)
   3. PS50025 (LAM_G_DOMAIN)
      2,266 - 2,480
      PROSITE profiles
      PS50025 (LAM_G_DOMAIN)
      2,519 - 2,710
      PROSITE profiles
      PS50025 (LAM_G_DOMAIN)
8. IPR000233
   Cadherin, cytoplasmic domain
   1. PF01049 (Cadherin_C)
      2,902 - 3,017
      Pfam
      PF01049 (Cadherin_C)
9. IPR027397
   Catenin binding domain
   1. G3DSA:4.10.90...
      2,962 - 3,017
      GENE3D
      G3DSA:4.10.900.10 (G3DSA:4.10.900.10)
10. IPR020894
    Cadherin conserved site
    1. PS00232 (CADHERIN_1)
       1,503 - 1,513
       PROSITE patterns
       PS00232 (CADHERIN_1)
       1,387 - 1,397
       PROSITE patterns
       PS00232 (CADHERIN_1)
       1,287 - 1,297
       PROSITE patterns
       PS00232 (CADHERIN_1)
       617 - 627
       PROSITE patterns
       PS00232 (CADHERIN_1)
       1,734 - 1,744
       PROSITE patterns
       PS00232 (CADHERIN_1)
       1,839 - 1,849
       PROSITE patterns
       PS00232 (CADHERIN_1)
11. IPR013032
    EGF-like, conserved site
    1. PS00022 (EGF_1)
       2,854 - 2,865
       PROSITE patterns
       PS00022 (EGF_1)
       2,253 - 2,264
       PROSITE patterns
       PS00022 (EGF_1)
       2,504 - 2,515
       PROSITE patterns
       PS00022 (EGF_1)
       2,779 - 2,790
       PROSITE patterns
       PS00022 (EGF_1)
    2. PS01186 (EGF_2)
       2,779 - 2,790
       PROSITE patterns
       PS01186 (EGF_2)
       2,854 - 2,865
       PROSITE patterns
       PS01186 (EGF_2)
       2,253 - 2,264
       PROSITE patterns
       PS01186 (EGF_2)
       2,504 - 2,515
       PROSITE patterns
       PS01186 (EGF_2)

no IPR
Unintegrated signatures

1. G3DSA:2.10.25.10
   2,762 - 2,793
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   2,231 - 2,250
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   2,469 - 2,503
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   2,710 - 2,761
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   2,831 - 2,869
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
2. PTHR24027 (FAMILY N...)
   539 - 3,018
   PANTHER
   PTHR24027 (FAMILY NOT NAMED)
3. PTHR24027:SF184 (SU...)
   539 - 3,018
   PANTHER
   PTHR24027:SF184 (SUBFAMILY NOT NAMED)
4. SSF57196 (EGF/Laminin)
   2,754 - 2,795
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   2,715 - 2,771
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   2,829 - 2,872
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
5. SignalP-TM
   1 - 32
   SignalP Gram+ prok
   SignalP-TM (SignalP-TM)
6. SignalP-noTM
   1 - 32
   SignalP euk
   SignalP-noTM (SignalP-noTM)
   1 - 32
   SignalP euk
   SignalP-noTM (SignalP-noTM)
7. TMhelix
   2,879 - 2,901
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion

#### Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

#### Cellular Component

GO:0005886 plasma membrane
GO:0016020 membrane