Protein

## EMLSAP00000003726

Length
1,931 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   281 - 389
   - Immunoglobulin-like fold (IPR013783)
     - Immunoglobulin-like domain (IPR007110)
   513 - 603
   - Immunoglobulin-like fold (IPR013783)
     - Immunoglobulin-like domain (IPR007110)
   734 - 840
   - Immunoglobulin-like fold (IPR013783)
     - Immunoglobulin-like domain (IPR007110)
   1,070 - 1,167
   - Insulin-like growth factor binding protein, N-terminal (IPR009030)
   1,184 - 1,380
   - Immunoglobulin-like fold (IPR013783)
     - Immunoglobulin-like domain (IPR007110)
   1,384 - 1,486
   - Immunoglobulin-like fold (IPR013783)
     - Immunoglobulin-like domain (IPR007110)
   1,575 - 1,678
   - Immunoglobulin-like fold (IPR013783)
     - Immunoglobulin-like domain (IPR007110)
   1,690 - 1,741
   - Immunoglobulin-like fold (IPR013783)
2. Domain
   308 - 386
   - Immunoglobulin subtype (IPR003599)
   523 - 602
   - Immunoglobulin subtype (IPR003599)
   741 - 837
   - Immunoglobulin subtype (IPR003599)
   1,192 - 1,283
   - Immunoglobulin subtype (IPR003599)
   1,306 - 1,383
   - Immunoglobulin subtype (IPR003599)
   1,405 - 1,484
   - Immunoglobulin subtype (IPR003599)
   1,501 - 1,582
   - Immunoglobulin subtype (IPR003599)
   1,592 - 1,673
   - Immunoglobulin subtype (IPR003599)
   1,675 - 1,740
   - Immunoglobulin subtype (IPR003599)
3. Domain
   314 - 375
   - Immunoglobulin subtype 2 (IPR003598)
   529 - 591
   - Immunoglobulin subtype 2 (IPR003598)
   747 - 818
   - Immunoglobulin subtype 2 (IPR003598)
   1,198 - 1,272
   - Immunoglobulin subtype 2 (IPR003598)
   1,312 - 1,372
   - Immunoglobulin subtype 2 (IPR003598)
   1,411 - 1,470
   - Immunoglobulin subtype 2 (IPR003598)
   1,507 - 1,572
   - Immunoglobulin subtype 2 (IPR003598)
   1,598 - 1,662
   - Immunoglobulin subtype 2 (IPR003598)
   1,673 - 1,729
   - Immunoglobulin subtype 2 (IPR003598)
4. Domain
   734 - 820
   - Immunoglobulin I-set (IPR013098)
   892 - 1,095
   - Laminin B type IV (IPR000034)
     - Laminin B, subgroup (IPR018031)
   1,189 - 1,282
   - Immunoglobulin I-set (IPR013098)
   1,499 - 1,565
   - Immunoglobulin I-set (IPR013098)
   1,593 - 1,672
   - Immunoglobulin I-set (IPR013098)
5. Domain
   1,486 - 1,566
   - Immunoglobulin-like fold (IPR013783)
     - Immunoglobulin-like domain (IPR007110)
6. Repeat
   111 - 150
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)
   187 - 232
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)
   391 - 429
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)
   432 - 470
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)
   473 - 512
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)
   611 - 649
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)
   652 - 689
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)
   695 - 735
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)
   1,800 - 1,840
   - Low-density lipoprotein (LDL) receptor class A repeat (IPR002172)

1 200 400 600 800 1000 1200 1400 1600 1800 1931

### Detailed signature matches

1. IPR003599
   Immunoglobulin subtype
   1. SM00409 (IG)
      1,192 - 1,283
      SMART
      SM00409 (IG)
      523 - 602
      SMART
      SM00409 (IG)
      1,675 - 1,740
      SMART
      SM00409 (IG)
      1,592 - 1,673
      SMART
      SM00409 (IG)
      1,405 - 1,484
      SMART
      SM00409 (IG)
      308 - 386
      SMART
      SM00409 (IG)
      1,501 - 1,582
      SMART
      SM00409 (IG)
      741 - 837
      SMART
      SM00409 (IG)
      1,306 - 1,383
      SMART
      SM00409 (IG)
2. IPR013783
   Immunoglobulin-like fold
   1. G3DSA:2.60.40.10
      1,402 - 1,486
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      1,575 - 1,678
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      1,497 - 1,566
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      734 - 840
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      1,313 - 1,370
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      309 - 355
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      531 - 603
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      1,189 - 1,312
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      356 - 389
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      513 - 530
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
      1,690 - 1,741
      GENE3D
      G3DSA:2.60.40.10 (G3DSA:2.60.40.10)
3. IPR007110
   Immunoglobulin-like domain
   1. PS50835 (IG_LIKE)
      734 - 816
      PROSITE profiles
      PS50835 (IG_LIKE)
      1,300 - 1,380
      PROSITE profiles
      PS50835 (IG_LIKE)
      1,184 - 1,281
      PROSITE profiles
      PS50835 (IG_LIKE)
      281 - 386
      PROSITE profiles
      PS50835 (IG_LIKE)
      515 - 600
      PROSITE profiles
      PS50835 (IG_LIKE)
      1,486 - 1,566
      PROSITE profiles
      PS50835 (IG_LIKE)
      1,585 - 1,671
      PROSITE profiles
      PS50835 (IG_LIKE)
      1,384 - 1,482
      PROSITE profiles
      PS50835 (IG_LIKE)
4. IPR003598
   Immunoglobulin subtype 2
   1. SM00408 (IGc2)
      1,598 - 1,662
      SMART
      SM00408 (IGc2)
      1,673 - 1,729
      SMART
      SM00408 (IGc2)
      1,411 - 1,470
      SMART
      SM00408 (IGc2)
      747 - 818
      SMART
      SM00408 (IGc2)
      1,198 - 1,272
      SMART
      SM00408 (IGc2)
      1,312 - 1,372
      SMART
      SM00408 (IGc2)
      1,507 - 1,572
      SMART
      SM00408 (IGc2)
      529 - 591
      SMART
      SM00408 (IGc2)
      314 - 375
      SMART
      SM00408 (IGc2)
5. IPR013098
   Immunoglobulin I-set
   1. PF07679 (I-set)
      734 - 820
      Pfam
      PF07679 (I-set)
      1,189 - 1,282
      Pfam
      PF07679 (I-set)
      1,593 - 1,672
      Pfam
      PF07679 (I-set)
      1,499 - 1,565
      Pfam
      PF07679 (I-set)
6. IPR000034
   Laminin B type IV
   1. PS51115 (LAMININ_IVA)
      892 - 1,095
      PROSITE profiles
      PS51115 (LAMININ_IVA)
   2. PF00052 (Laminin_B)
      947 - 1,065
      Pfam
      PF00052 (Laminin_B)
7. IPR018031
   Laminin B, subgroup
   1. SM00281 (LamB)
      933 - 1,062
      SMART
      SM00281 (LamB)
8. IPR009030
   Insulin-like growth factor binding protein, N-terminal
   1. SSF57184 (Growth fa...)
      1,070 - 1,167
      SUPERFAMILY
      SSF57184 (Growth factor receptor domain)
9. IPR002172
   Low-density lipoprotein (LDL) receptor class A repeat
   1. PS50068 (LDLRA_2)
      695 - 732
      PROSITE profiles
      PS50068 (LDLRA_2)
      652 - 688
      PROSITE profiles
      PS50068 (LDLRA_2)
      391 - 428
      PROSITE profiles
      PS50068 (LDLRA_2)
      112 - 149
      PROSITE profiles
      PS50068 (LDLRA_2)
      612 - 648
      PROSITE profiles
      PS50068 (LDLRA_2)
      1,801 - 1,839
      PROSITE profiles
      PS50068 (LDLRA_2)
      474 - 511
      PROSITE profiles
      PS50068 (LDLRA_2)
      432 - 469
      PROSITE profiles
      PS50068 (LDLRA_2)
   2. SSF57424 (LDL recep...)
      474 - 510
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
      653 - 689
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
      112 - 148
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
      433 - 469
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
      392 - 427
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
      695 - 735
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
      611 - 647
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
      1,807 - 1,840
      SUPERFAMILY
      SSF57424 (LDL receptor-like module)
   3. PF00057 (Ldl_recept_a)
      613 - 647
      Pfam
      PF00057 (Ldl_recept_a)
      432 - 468
      Pfam
      PF00057 (Ldl_recept_a)
      473 - 510
      Pfam
      PF00057 (Ldl_recept_a)
      695 - 731
      Pfam
      PF00057 (Ldl_recept_a)
      652 - 687
      Pfam
      PF00057 (Ldl_recept_a)
      111 - 148
      Pfam
      PF00057 (Ldl_recept_a)
      1,801 - 1,838
      Pfam
      PF00057 (Ldl_recept_a)
   4. PR00261 (LDLRECEPTOR)
      444 - 465
      PRINTS
      PR00261 (LDLRECEPTOR)
      486 - 507
      PRINTS
      PR00261 (LDLRECEPTOR)
      623 - 644
      PRINTS
      PR00261 (LDLRECEPTOR)
      663 - 684
      PRINTS
      PR00261 (LDLRECEPTOR)
      707 - 728
      PRINTS
      PR00261 (LDLRECEPTOR)
      403 - 424
      PRINTS
      PR00261 (LDLRECEPTOR)
   5. G3DSA:4.10.40...
      695 - 733
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
      1,800 - 1,840
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
      653 - 688
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
      111 - 148
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
      474 - 510
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
      396 - 427
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
      436 - 468
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
      612 - 647
      GENE3D
      G3DSA:4.10.400.10 (G3DSA:4.10.400.10)
   6. SM00192 (LDLa)
      112 - 150
      SMART
      SM00192 (LDLa)
      1,801 - 1,840
      SMART
      SM00192 (LDLa)
      432 - 470
      SMART
      SM00192 (LDLa)
      187 - 232
      SMART
      SM00192 (LDLa)
      391 - 429
      SMART
      SM00192 (LDLa)
      474 - 512
      SMART
      SM00192 (LDLa)
      695 - 733
      SMART
      SM00192 (LDLa)
      612 - 649
      SMART
      SM00192 (LDLa)
      652 - 689
      SMART
      SM00192 (LDLa)
10. IPR023415
    Low-density lipoprotein (LDL) receptor class A, conserved site
    1. PS01209 (LDLRA_1)
       126 - 148
       PROSITE patterns
       PS01209 (LDLRA_1)
       665 - 687
       PROSITE patterns
       PS01209 (LDLRA_1)
       405 - 427
       PROSITE patterns
       PS01209 (LDLRA_1)
       709 - 731
       PROSITE patterns
       PS01209 (LDLRA_1)
       446 - 468
       PROSITE patterns
       PS01209 (LDLRA_1)
       1,816 - 1,838
       PROSITE patterns
       PS01209 (LDLRA_1)
       625 - 647
       PROSITE patterns
       PS01209 (LDLRA_1)
       488 - 510
       PROSITE patterns
       PS01209 (LDLRA_1)

no IPR
Unintegrated signatures

1. PF13895 (Ig_2)
   523 - 601
   Pfam
   PF13895 (Ig_2)
   1,856 - 1,921
   Pfam
   PF13895 (Ig_2)
   1,304 - 1,375
   Pfam
   PF13895 (Ig_2)
   307 - 387
   Pfam
   PF13895 (Ig_2)
   1,401 - 1,472
   Pfam
   PF13895 (Ig_2)
2. PTHR10489 (CELL ADH...)
   1,189 - 1,740
   PANTHER
   PTHR10489 (CELL ADHESION MOLECULE)
3. SSF48726 (Immunoglo...)
   1,189 - 1,283
   SUPERFAMILY
   SSF48726 (Immunoglobulin)
   732 - 820
   SUPERFAMILY
   SSF48726 (Immunoglobulin)
   304 - 387
   SUPERFAMILY
   SSF48726 (Immunoglobulin)
   1,688 - 1,739
   SUPERFAMILY
   SSF48726 (Immunoglobulin)
   1,592 - 1,682
   SUPERFAMILY
   SSF48726 (Immunoglobulin)
   1,401 - 1,497
   SUPERFAMILY
   SSF48726 (Immunoglobulin)
   1,299 - 1,383
   SUPERFAMILY
   SSF48726 (Immunoglobulin)
   1,496 - 1,589
   SUPERFAMILY
   SSF48726 (Immunoglobulin)
   520 - 603
   SUPERFAMILY
   SSF48726 (Immunoglobulin)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0005515 protein binding

#### Cellular Component

None predicted.