Protein

## EMLSAP00000004952

Length
1,579 amino acids

### Protein family membership

- Voltage-dependent calcium channel, alpha-1 subunit (IPR002077)

### Domains and repeats

1. Domain
   58 - 180
   - Voltage-dependent channel, four helix bundle domain (IPR027359)
   400 - 454
   - Voltage-dependent channel, four helix bundle domain (IPR027359)
   740 - 791
   - Voltage-dependent channel, four helix bundle domain (IPR027359)
   994 - 1,111
   - Voltage-dependent channel, four helix bundle domain (IPR027359)
2. Domain
   106 - 294
   - Ion transport domain (IPR005821)
   403 - 501
   - Ion transport domain (IPR005821)
   735 - 949
   - Ion transport domain (IPR005821)
   1,038 - 1,246
   - Ion transport domain (IPR005821)
   1,385 - 1,419
   - Voltage-dependent calcium channel, alpha-1 subunit, IQ domain (IPR014873)

1 200 400 600 800 1000 1200 1400 1579

### Detailed signature matches

1. IPR002077
   Voltage-dependent calcium channel, alpha-1 subunit
   1. PR00167 (CACHANNEL)
      951 - 971
      PRINTS
      PR00167 (CACHANNEL)
      188 - 203
      PRINTS
      PR00167 (CACHANNEL)
      1,121 - 1,135
      PRINTS
      PR00167 (CACHANNEL)
      1,169 - 1,181
      PRINTS
      PR00167 (CACHANNEL)
2. IPR027359
   Voltage-dependent channel, four helix bundle domain
   1. G3DSA:1.20.12...
      58 - 180
      GENE3D
      G3DSA:1.20.120.350 (G3DSA:1.20.120.350)
      994 - 1,111
      GENE3D
      G3DSA:1.20.120.350 (G3DSA:1.20.120.350)
      740 - 791
      GENE3D
      G3DSA:1.20.120.350 (G3DSA:1.20.120.350)
      400 - 454
      GENE3D
      G3DSA:1.20.120.350 (G3DSA:1.20.120.350)
3. IPR005821
   Ion transport domain
   1. PF00520 (Ion_trans)
      1,038 - 1,246
      Pfam
      PF00520 (Ion_trans)
      106 - 294
      Pfam
      PF00520 (Ion_trans)
      735 - 949
      Pfam
      PF00520 (Ion_trans)
      403 - 501
      Pfam
      PF00520 (Ion_trans)
4. IPR014873
   Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
   1. SM01062 (Ca_chan_IQ)
      1,385 - 1,419
      SMART
      SM01062 (Ca_chan_IQ)
   2. PF08763 (Ca_chan_IQ)
      1,386 - 1,416
      Pfam
      PF08763 (Ca_chan_IQ)

no IPR
Unintegrated signatures

1. Coil
   648 - 669
   COILS
   Coil (Coil)
2. PTHR10037 (VOLTAGE-...)
   38 - 1,483
   PANTHER
   PTHR10037 (VOLTAGE-GATED CATION CHANNEL (CALCIUM AND SODIUM))
3. PTHR10037:SF50 (VOL...)
   38 - 1,483
   PANTHER
   PTHR10037:SF50 (VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE D-RELATED)
4. SSF81324 (Voltage-g...)
   701 - 838
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   878 - 956
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   1,003 - 1,250
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   67 - 226
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   268 - 292
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   402 - 558
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
5. TMhelix
   1,005 - 1,024
   TMHMM
   TMhelix (TMhelix)
   801 - 823
   TMHMM
   TMhelix (TMhelix)
   1,131 - 1,150
   TMHMM
   TMhelix (TMhelix)
   927 - 949
   TMHMM
   TMhelix (TMhelix)
   108 - 127
   TMHMM
   TMhelix (TMhelix)
   69 - 88
   TMHMM
   TMhelix (TMhelix)
   1,073 - 1,095
   TMHMM
   TMhelix (TMhelix)
   698 - 720
   TMHMM
   TMhelix (TMhelix)
   197 - 219
   TMHMM
   TMhelix (TMhelix)
   139 - 161
   TMHMM
   TMhelix (TMhelix)
   1,224 - 1,246
   TMHMM
   TMhelix (TMhelix)
   473 - 495
   TMHMM
   TMhelix (TMhelix)
   525 - 547
   TMHMM
   TMhelix (TMhelix)
   1,034 - 1,052
   TMHMM
   TMhelix (TMhelix)
   756 - 778
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006811 ion transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport

#### Molecular Function

GO:0005216 ion channel activity
GO:0005245 voltage-gated calcium channel activity

#### Cellular Component

GO:0005891 voltage-gated calcium channel complex
GO:0016020 membrane