Protein

## EMLSAP00000000317

Length
982 amino acids

### Protein family membership

- Haem peroxidase (IPR010255)
  - Haem peroxidase, animal (IPR002007)

### Domains and repeats

1. Domain
   410 - 526
   - EF-hand domain pair (IPR011992)
2. Domain
   425 - 460
   - EF-hand domain (IPR002048)
   462 - 497
   - EF-hand domain (IPR002048)
   597 - 687
   - Ferric reductase transmembrane component-like domain (IPR013130)
   723 - 846
   - Riboflavin synthase-like beta-barrel (IPR017938)
     - Ferredoxin reductase-type FAD-binding domain (IPR017927)
       - FAD-binding 8 (IPR013112)
   850 - 929
   - Ferric reductase, NAD binding (IPR013121)

1 100 200 300 400 500 600 700 800 900 982

### Detailed signature matches

1. IPR010255
   Haem peroxidase
   1. SSF48113 (Heme-depe...)
      1 - 182
      SUPERFAMILY
      SSF48113 (Heme-dependent peroxidases)
2. IPR002007
   Haem peroxidase, animal
   1. PF03098 (An_peroxidase)
      2 - 130
      Pfam
      PF03098 (An_peroxidase)
   2. G3DSA:1.10.64...
      135 - 182
      GENE3D
      G3DSA:1.10.640.10 (G3DSA:1.10.640.10)
      1 - 131
      GENE3D
      G3DSA:1.10.640.10 (G3DSA:1.10.640.10)
   3. PS50292 (PEROXIDASE_3)
      1 - 271
      PROSITE profiles
      PS50292 (PEROXIDASE_3)
3. IPR011992
   EF-hand domain pair
   1. G3DSA:1.10.23...
      410 - 526
      GENE3D
      G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
4. IPR002048
   EF-hand domain
   1. PF13405 (EF-hand_6)
      470 - 492
      Pfam
      PF13405 (EF-hand_6)
   2. SM00054 (EFh)
      429 - 457
      SMART
      SM00054 (EFh)
      466 - 494
      SMART
      SM00054 (EFh)
   3. PS50222 (EF_HAND_2)
      462 - 497
      PROSITE profiles
      PS50222 (EF_HAND_2)
      425 - 460
      PROSITE profiles
      PS50222 (EF_HAND_2)
   4. PF00036 (EF-hand_1)
      430 - 454
      Pfam
      PF00036 (EF-hand_1)
5. IPR013130
   Ferric reductase transmembrane component-like domain
   1. PF01794 (Ferric_reduct)
      597 - 687
      Pfam
      PF01794 (Ferric_reduct)
6. IPR017938
   Riboflavin synthase-like beta-barrel
   1. SSF63380 (Riboflavi...)
      726 - 841
      SUPERFAMILY
      SSF63380 (Riboflavin synthase domain-like)
7. IPR017927
   Ferredoxin reductase-type FAD-binding domain
   1. PS51384 (FAD_FR)
      723 - 846
      PROSITE profiles
      PS51384 (FAD_FR)
8. IPR013112
   FAD-binding 8
   1. PF08022 (FAD_binding_8)
      730 - 841
      Pfam
      PF08022 (FAD_binding_8)
9. IPR013121
   Ferric reductase, NAD binding
   1. PF08030 (NAD_binding_6)
      850 - 929
      Pfam
      PF08030 (NAD_binding_6)
10. IPR018247
    EF-Hand 1, calcium-binding site
    1. PS00018 (EF_HAND_1)
       438 - 450
       PROSITE patterns
       PS00018 (EF_HAND_1)
       475 - 487
       PROSITE patterns
       PS00018 (EF_HAND_1)

no IPR
Unintegrated signatures

1. G3DSA:2.40.30.10
   726 - 808
   GENE3D
   G3DSA:2.40.30.10 (G3DSA:2.40.30.10)
2. G3DSA:3.40.50.80
   853 - 980
   GENE3D
   G3DSA:3.40.50.80 (G3DSA:3.40.50.80)
3. PTHR11972 (NADPH OX...)
   343 - 982
   PANTHER
   PTHR11972 (NADPH OXIDASE)
4. PTHR11972:SF6 (DUAL...)
   343 - 982
   PANTHER
   PTHR11972:SF6 (DUAL OXIDASE 1, 2)
5. SSF47473 (EF-hand)
   412 - 515
   SUPERFAMILY
   SSF47473 (EF-hand)
6. SSF52343 (Ferredoxi...)
   852 - 981
   SUPERFAMILY
   SSF52343 (Ferredoxin reductase-like, C-terminal NADP-linked domain)
7. TMhelix
   671 - 693
   TMHMM
   TMhelix (TMhelix)
   208 - 230
   TMHMM
   TMhelix (TMhelix)
   642 - 664
   TMHMM
   TMhelix (TMhelix)
   565 - 587
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006979 response to oxidative stress
GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0004601 peroxidase activity
GO:0005509 calcium ion binding
GO:0016491 oxidoreductase activity
GO:0020037 heme binding

#### Cellular Component

None predicted.