Protein

## EMLSAP00000002121

Length
841 amino acids

### Protein family membership

- Arf GTPase activating protein (IPR001164)

### Domains and repeats

1. Domain
   80 - 163
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   376 - 575
   - Pleckstrin homology-like domain (IPR011993)
     - Pleckstrin homology domain (IPR001849)
   643 - 669
   - Ankyrin repeat-containing domain (IPR020683)
   712 - 809
   - Ankyrin repeat-containing domain (IPR020683)
2. Repeat
   751 - 783
   - Ankyrin repeat (IPR002110)
   784 - 814
   - Ankyrin repeat (IPR002110)

1 100 200 300 400 500 600 700 841

### Detailed signature matches

1. IPR001164
   Arf GTPase activating protein
   1. PF01412 (ArfGap)
      594 - 706
      Pfam
      PF01412 (ArfGap)
   2. SM00105 (ArfGap)
      589 - 713
      SMART
      SM00105 (ArfGap)
   3. PR00405 (REVINTRACTNG)
      605 - 624
      PRINTS
      PR00405 (REVINTRACTNG)
      645 - 666
      PRINTS
      PR00405 (REVINTRACTNG)
      624 - 641
      PRINTS
      PR00405 (REVINTRACTNG)
   4. PS50115 (ARFGAP)
      592 - 713
      PROSITE profiles
      PS50115 (ARFGAP)
2. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      80 - 163
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
3. IPR011993
   Pleckstrin homology-like domain
   1. G3DSA:2.30.29.30
      377 - 433
      GENE3D
      G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
      526 - 575
      GENE3D
      G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
4. IPR001849
   Pleckstrin homology domain
   1. PF00169 (PH)
      378 - 569
      Pfam
      PF00169 (PH)
   2. SM00233 (PH)
      377 - 573
      SMART
      SM00233 (PH)
   3. PS50003 (PH_DOMAIN)
      376 - 571
      PROSITE profiles
      PS50003 (PH_DOMAIN)
5. IPR020683
   Ankyrin repeat-containing domain
   1. PS50297 (ANK_REP_RE...)
      751 - 808
      PROSITE profiles
      PS50297 (ANK_REP_REGION)
   2. G3DSA:1.25.40.20
      719 - 809
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
   3. PF12796 (Ank_2)
      720 - 809
      Pfam
      PF12796 (Ank_2)
   4. SSF48403 (Ankyrin r...)
      643 - 669
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
      712 - 809
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
6. IPR002110
   Ankyrin repeat
   1. SM00248 (ANK)
      784 - 814
      SMART
      SM00248 (ANK)
      751 - 780
      SMART
      SM00248 (ANK)
   2. PS50088 (ANK_REPEAT)
      751 - 783
      PROSITE profiles
      PS50088 (ANK_REPEAT)

no IPR
Unintegrated signatures

1. G3DSA:3.40.50...
   111 - 165
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
2. PTHR23180 (CENTAURI...)
   41 - 817
   PANTHER
   PTHR23180 (CENTAURIN/ARF)
3. PTHR23180:SF6 (CENT...)
   41 - 817
   PANTHER
   PTHR23180:SF6 (CENTAURIN/ARF-RELATED)
4. SSF50729 (PH domain...)
   537 - 581
   SUPERFAMILY
   SSF50729 (PH domain-like)
   370 - 442
   SUPERFAMILY
   SSF50729 (PH domain-like)
5. SSF57863 (ArfGap/Re...)
   601 - 707
   SUPERFAMILY
   SSF57863 (ArfGap/RecO-like zinc finger)

### GO term prediction

#### Biological Process

GO:0032312 regulation of ARF GTPase activity

#### Molecular Function

GO:0005515 protein binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding

#### Cellular Component

None predicted.