Protein

## EMLSAP00000002446

Length
783 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   84 - 129
   - Epidermal growth factor-like domain (IPR000742)
   187 - 230
   - Epidermal growth factor-like domain (IPR000742)
   287 - 330
   - Epidermal growth factor-like domain (IPR000742)
   334 - 378
   - Epidermal growth factor-like domain (IPR000742)
   399 - 438
   - Epidermal growth factor-like domain (IPR000742)
   439 - 480
   - Epidermal growth factor-like domain (IPR000742)
   481 - 520
   - Epidermal growth factor-like domain (IPR000742)
   521 - 561
   - Epidermal growth factor-like domain (IPR000742)
   562 - 602
   - Epidermal growth factor-like domain (IPR000742)
   606 - 651
   - Epidermal growth factor-like domain (IPR000742)
2. Domain
   165 - 448
   - Insulin-like growth factor binding protein, N-terminal (IPR009030)
   522 - 658
   - Insulin-like growth factor binding protein, N-terminal (IPR009030)
3. Domain
   184 - 230
   - EGF-like calcium-binding domain (IPR001881)
   231 - 283
   - EGF-like calcium-binding domain (IPR001881)
   284 - 330
   - EGF-like calcium-binding domain (IPR001881)
   331 - 378
   - EGF-like calcium-binding domain (IPR001881)
   396 - 438
   - EGF-like calcium-binding domain (IPR001881)
   439 - 480
   - EGF-like calcium-binding domain (IPR001881)
   481 - 520
   - EGF-like calcium-binding domain (IPR001881)
   521 - 561
   - EGF-like calcium-binding domain (IPR001881)
   562 - 602
   - EGF-like calcium-binding domain (IPR001881)
   603 - 651
   - EGF-like calcium-binding domain (IPR001881)
4. Domain
   542 - 565
   - Complement Clr-like EGF domain (IPR026823)
   583 - 606
   - Complement Clr-like EGF domain (IPR026823)

1 100 200 300 400 500 600 700 783

### Detailed signature matches

1. IPR000742
   Epidermal growth factor-like domain
   1. PS50026 (EGF_3)
      562 - 602
      PROSITE profiles
      PS50026 (EGF_3)
      439 - 478
      PROSITE profiles
      PS50026 (EGF_3)
      521 - 561
      PROSITE profiles
      PS50026 (EGF_3)
      481 - 518
      PROSITE profiles
      PS50026 (EGF_3)
   2. SM00181 (EGF)
      524 - 561
      SMART
      SM00181 (EGF)
      484 - 520
      SMART
      SM00181 (EGF)
      565 - 602
      SMART
      SM00181 (EGF)
      334 - 378
      SMART
      SM00181 (EGF)
      606 - 651
      SMART
      SM00181 (EGF)
      84 - 129
      SMART
      SM00181 (EGF)
      187 - 230
      SMART
      SM00181 (EGF)
      287 - 330
      SMART
      SM00181 (EGF)
      399 - 438
      SMART
      SM00181 (EGF)
      442 - 480
      SMART
      SM00181 (EGF)
2. IPR009030
   Insulin-like growth factor binding protein, N-terminal
   1. SSF57184 (Growth fa...)
      522 - 658
      SUPERFAMILY
      SSF57184 (Growth factor receptor domain)
      165 - 284
      SUPERFAMILY
      SSF57184 (Growth factor receptor domain)
      268 - 448
      SUPERFAMILY
      SSF57184 (Growth factor receptor domain)
3. IPR001881
   EGF-like calcium-binding domain
   1. SM00179 (EGF_CA)
      439 - 480
      SMART
      SM00179 (EGF_CA)
      284 - 330
      SMART
      SM00179 (EGF_CA)
      396 - 438
      SMART
      SM00179 (EGF_CA)
      331 - 378
      SMART
      SM00179 (EGF_CA)
      521 - 561
      SMART
      SM00179 (EGF_CA)
      231 - 283
      SMART
      SM00179 (EGF_CA)
      562 - 602
      SMART
      SM00179 (EGF_CA)
      603 - 651
      SMART
      SM00179 (EGF_CA)
      481 - 520
      SMART
      SM00179 (EGF_CA)
      184 - 230
      SMART
      SM00179 (EGF_CA)
   2. PF07645 (EGF_CA)
      284 - 329
      Pfam
      PF07645 (EGF_CA)
      481 - 519
      Pfam
      PF07645 (EGF_CA)
      396 - 437
      Pfam
      PF07645 (EGF_CA)
      331 - 368
      Pfam
      PF07645 (EGF_CA)
      231 - 282
      Pfam
      PF07645 (EGF_CA)
      439 - 477
      Pfam
      PF07645 (EGF_CA)
      184 - 223
      Pfam
      PF07645 (EGF_CA)
4. IPR026823
   Complement Clr-like EGF domain
   1. PF12662 (cEGF)
      542 - 565
      Pfam
      PF12662 (cEGF)
      583 - 606
      Pfam
      PF12662 (cEGF)
5. IPR018097
   EGF-like calcium-binding, conserved site
   1. PS01187 (EGF_CA)
      603 - 630
      PROSITE patterns
      PS01187 (EGF_CA)
      439 - 466
      PROSITE patterns
      PS01187 (EGF_CA)
      481 - 506
      PROSITE patterns
      PS01187 (EGF_CA)
      231 - 257
      PROSITE patterns
      PS01187 (EGF_CA)
      284 - 310
      PROSITE patterns
      PS01187 (EGF_CA)
      521 - 545
      PROSITE patterns
      PS01187 (EGF_CA)
      562 - 586
      PROSITE patterns
      PS01187 (EGF_CA)
      396 - 420
      PROSITE patterns
      PS01187 (EGF_CA)
6. IPR000152
   EGF-type aspartate/asparagine hydroxylation site
   1. PS00010 (ASX_HYDROXYL)
      536 - 547
      PROSITE patterns
      PS00010 (ASX_HYDROXYL)
      577 - 588
      PROSITE patterns
      PS00010 (ASX_HYDROXYL)
      457 - 468
      PROSITE patterns
      PS00010 (ASX_HYDROXYL)
      497 - 508
      PROSITE patterns
      PS00010 (ASX_HYDROXYL)
7. IPR013032
   EGF-like, conserved site
   1. PS01186 (EGF_2)
      466 - 479
      PROSITE patterns
      PS01186 (EGF_2)
      586 - 601
      PROSITE patterns
      PS01186 (EGF_2)
      506 - 519
      PROSITE patterns
      PS01186 (EGF_2)
      545 - 560
      PROSITE patterns
      PS01186 (EGF_2)

no IPR
Unintegrated signatures

1. G3DSA:2.10.25.10
   334 - 380
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   290 - 333
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   445 - 515
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   183 - 223
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   616 - 664
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   394 - 444
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   229 - 289
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   518 - 571
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   572 - 615
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
2. PTHR24048 (FAMILY N...)
   169 - 783
   PANTHER
   PTHR24048 (FAMILY NOT NAMED)
3. SSF57196 (EGF/Laminin)
   481 - 516
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
   434 - 475
   SUPERFAMILY
   SSF57196 (EGF/Laminin)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

#### Cellular Component

None predicted.