Protein

## EMLSAP00000007385

Length
330 amino acids

### Protein family membership

- Ribonuclease H1, eukaryote (IPR017067)

### Domains and repeats

1. Domain
   19 - 65
   - Ribosomal protein L9/RNase H1, N-terminal (IPR009027)
     - Ribonuclease H1, N-terminal (IPR011320)
   90 - 136
   - Ribosomal protein L9/RNase H1, N-terminal (IPR009027)
     - Ribonuclease H1, N-terminal (IPR011320)
   183 - 330
   - Ribonuclease H-like domain (IPR012337)
     - Ribonuclease H domain (IPR002156)

1 50 100 150 200 250 300 330

### Detailed signature matches

1. IPR017067
   Ribonuclease H1, eukaryote
   1. PIRSF036852 (RNase_...)
      11 - 330
      PIRSF
      PIRSF036852 (RNase_H1_euk)
2. IPR009027
   Ribosomal protein L9/RNase H1, N-terminal
   1. SSF55658 (L9 N-doma...)
      90 - 134
      SUPERFAMILY
      SSF55658 (L9 N-domain-like)
      19 - 63
      SUPERFAMILY
      SSF55658 (L9 N-domain-like)
3. IPR011320
   Ribonuclease H1, N-terminal
   1. G3DSA:3.40.97...
      19 - 65
      GENE3D
      G3DSA:3.40.970.10 (G3DSA:3.40.970.10)
      90 - 136
      GENE3D
      G3DSA:3.40.970.10 (G3DSA:3.40.970.10)
   2. PF01693 (Cauli_VI)
      19 - 62
      Pfam
      PF01693 (Cauli_VI)
      90 - 133
      Pfam
      PF01693 (Cauli_VI)
4. IPR012337
   Ribonuclease H-like domain
   1. SSF53098 (Ribonucle...)
      185 - 329
      SUPERFAMILY
      SSF53098 (Ribonuclease H-like)
5. IPR002156
   Ribonuclease H domain
   1. PF00075 (RNase_H)
      187 - 329
      Pfam
      PF00075 (RNase_H)
   2. PS50879 (RNASE_H)
      183 - 330
      PROSITE profiles
      PS50879 (RNASE_H)

no IPR
Unintegrated signatures

1. G3DSA:3.30.42...
   187 - 330
   GENE3D
   G3DSA:3.30.420.10 (G3DSA:3.30.420.10)
2. PTHR10642 (RIBONUCL...)
   10 - 330
   PANTHER
   PTHR10642 (RIBONUCLEASE H1)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

#### Cellular Component

None predicted.