Protein

## EMLSAP00000002424

Length
1,275 amino acids

### Protein family membership

- Chaperonin Cpn60/TCP-1 (IPR002423)

### Domains and repeats

1. Domain
   115 - 502
   - Protein kinase-like domain (IPR011009)
     - Protein kinase domain (IPR000719)
       - Serine/threonine- /dual specificity protein kinase, catalytic domain (IPR002290)
   591 - 623
   - LisH dimerisation motif (IPR006594)
   842 - 935
   - GroEL-like equatorial domain (IPR027413)
   1,007 - 1,098
   - GroEL-like apical domain (IPR027409)
   1,142 - 1,273
   - GroEL-like equatorial domain (IPR027413)

1 200 400 600 800 1000 1275

### Detailed signature matches

1. IPR002423
   Chaperonin Cpn60/TCP-1
   1. SSF48592 (GroEL equ...)
      1,141 - 1,175
      SUPERFAMILY
      SSF48592 (GroEL equatorial domain-like)
      839 - 934
      SUPERFAMILY
      SSF48592 (GroEL equatorial domain-like)
   2. PF00118 (Cpn60_TCP1)
      977 - 1,167
      Pfam
      PF00118 (Cpn60_TCP1)
      843 - 912
      Pfam
      PF00118 (Cpn60_TCP1)
2. IPR011009
   Protein kinase-like domain
   1. SSF56112 (Protein k...)
      115 - 197
      SUPERFAMILY
      SSF56112 (Protein kinase-like (PK-like))
      295 - 502
      SUPERFAMILY
      SSF56112 (Protein kinase-like (PK-like))
3. IPR000719
   Protein kinase domain
   1. PF00069 (Pkinase)
      298 - 498
      Pfam
      PF00069 (Pkinase)
      125 - 197
      Pfam
      PF00069 (Pkinase)
   2. PS50011 (PROTEIN_KI...)
      124 - 499
      PROSITE profiles
      PS50011 (PROTEIN_KINASE_DOM)
4. IPR002290
   Serine/threonine- /dual specificity protein kinase, catalytic domain
   1. SM00220 (S_TKc)
      124 - 499
      SMART
      SM00220 (S_TKc)
5. IPR006594
   LisH dimerisation motif
   1. PS50896 (LISH)
      591 - 623
      PROSITE profiles
      PS50896 (LISH)
6. IPR027413
   GroEL-like equatorial domain
   1. G3DSA:1.10.56...
      842 - 935
      GENE3D
      G3DSA:1.10.560.10 (G3DSA:1.10.560.10)
      1,142 - 1,273
      GENE3D
      G3DSA:1.10.560.10 (G3DSA:1.10.560.10)
7. IPR027409
   GroEL-like apical domain
   1. SSF52029 (GroEL api...)
      1,007 - 1,098
      SUPERFAMILY
      SSF52029 (GroEL apical domain-like)
   2. G3DSA:3.50.7.10
      1,012 - 1,097
      GENE3D
      G3DSA:3.50.7.10 (G3DSA:3.50.7.10)
8. IPR008271
   Serine/threonine-protein kinase, active site
   1. PS00108 (PROTEIN_KI...)
      350 - 362
      PROSITE patterns
      PS00108 (PROTEIN_KINASE_ST)

no IPR
Unintegrated signatures

1. Coil
   775 - 796
   COILS
   Coil (Coil)
   519 - 547
   COILS
   Coil (Coil)
   744 - 772
   COILS
   Coil (Coil)
2. G3DSA:1.10.51...
   314 - 501
   GENE3D
   G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
3. G3DSA:3.30.20...
   299 - 313
   GENE3D
   G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
   116 - 195
   GENE3D
   G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
4. PTHR11042 (EUKARYOT...)
   34 - 913
   PANTHER
   PTHR11042 (EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE (EIF2-ALPHA KINASE)-RELATED)
5. PTHR11042:SF60 (EUK...)
   34 - 913
   PANTHER
   PTHR11042:SF60 (EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1)

### GO term prediction

#### Biological Process

GO:0006468 protein phosphorylation
GO:0044267 cellular protein metabolic process

#### Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups

#### Cellular Component

None predicted.