Protein

## EMLSAP00000009047

Length
495 amino acids

### Protein family membership

- Neurotransmitter-gated ion-channel (IPR006201)
  - Gamma-aminobutyric acid A receptor (IPR006028)
    - Gamma-aminobutyric-acid A receptor, alpha subunit (IPR001390)

### Domains and repeats

1. Domain
   79 - 285
   - Neurotransmitter-gated ion-channel ligand-binding (IPR006202)
2. Domain
   285 - 493
   - Neurotransmitter-gated ion-channel transmembrane domain (IPR006029)

1 50 100 150 200 250 300 350 400 450 495

### Detailed signature matches

1. IPR006201
   Neurotransmitter-gated ion-channel
   1. PTHR18945 (NEUROTRA...)
      75 - 495
      PANTHER
      PTHR18945 (NEUROTRANSMITTER GATED ION CHANNEL)
   2. PR00252 (NRIONCHANNEL)
      279 - 291
      PRINTS
      PR00252 (NRIONCHANNEL)
      159 - 170
      PRINTS
      PR00252 (NRIONCHANNEL)
      205 - 219
      PRINTS
      PR00252 (NRIONCHANNEL)
      126 - 142
      PRINTS
      PR00252 (NRIONCHANNEL)
   3. TIGR00860
      72 - 492
      UNKNOWN
      TIGR00860 (TIGR00860)
2. IPR006028
   Gamma-aminobutyric acid A receptor
   1. PR00253 (GABAARECEPTR)
      288 - 308
      PRINTS
      PR00253 (GABAARECEPTR)
      314 - 335
      PRINTS
      PR00253 (GABAARECEPTR)
      472 - 492
      PRINTS
      PR00253 (GABAARECEPTR)
      348 - 369
      PRINTS
      PR00253 (GABAARECEPTR)
3. IPR001390
   Gamma-aminobutyric-acid A receptor, alpha subunit
   1. PR01079 (GABAARALPHA)
      462 - 474
      PRINTS
      PR01079 (GABAARALPHA)
      341 - 354
      PRINTS
      PR01079 (GABAARALPHA)
      98 - 115
      PRINTS
      PR01079 (GABAARALPHA)
      487 - 495
      PRINTS
      PR01079 (GABAARALPHA)
      248 - 270
      PRINTS
      PR01079 (GABAARALPHA)
      78 - 89
      PRINTS
      PR01079 (GABAARALPHA)
4. IPR006202
   Neurotransmitter-gated ion-channel ligand-binding
   1. PF02931 (Neur_chan_LBD)
      82 - 285
      Pfam
      PF02931 (Neur_chan_LBD)
   2. SSF63712 (Nicotinic...)
      79 - 284
      SUPERFAMILY
      SSF63712 (Nicotinic receptor ligand binding domain-like)
   3. G3DSA:2.70.17...
      94 - 284
      GENE3D
      G3DSA:2.70.170.10 (G3DSA:2.70.170.10)
5. IPR006029
   Neurotransmitter-gated ion-channel transmembrane domain
   1. SSF90112 (Neurotran...)
      285 - 493
      SUPERFAMILY
      SSF90112 (Neurotransmitter-gated ion-channel transmembrane pore)
   2. PF02932 (Neur_chan_...)
      433 - 489
      Pfam
      PF02932 (Neur_chan_memb)
      292 - 368
      Pfam
      PF02932 (Neur_chan_memb)
6. IPR018000
   Neurotransmitter-gated ion-channel, conserved site
   1. PS00236 (NEUROTR_IO...)
      205 - 219
      PROSITE patterns
      PS00236 (NEUROTR_ION_CHANNEL)

no IPR
Unintegrated signatures

1. G3DSA:1.20.58...
   285 - 377
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
   465 - 493
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
2. PTHR18945:SF207 (GA...)
   75 - 495
   PANTHER
   PTHR18945:SF207 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-RELATED)
3. TMhelix
   472 - 494
   TMHMM
   TMhelix (TMhelix)
   287 - 309
   TMHMM
   TMhelix (TMhelix)
   350 - 369
   TMHMM
   TMhelix (TMhelix)
   316 - 335
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006810 transport
GO:0006811 ion transport

#### Molecular Function

GO:0004890 GABA-A receptor activity
GO:0005216 ion channel activity
GO:0005230 extracellular ligand-gated ion channel activity

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane