Protein

## EMLSAP00000006872

Length
463 amino acids

### Protein family membership

- Aminoacyl-tRNA synthetase, class Ic (IPR002305)
  - Tyrosine-tRNA ligase (IPR002307)
    - Tyrosine-tRNA ligase, bacterial-type (IPR024088)
      - Tyrosine-tRNA ligase, bacterial-type, type 1 (IPR024107)

### Domains and repeats

1. Domain
   19 - 274
   - Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
   355 - 461
   - RNA-binding S4 domain (IPR002942)

1 50 100 150 200 250 300 350 400 463

### Detailed signature matches

1. IPR002305
   Aminoacyl-tRNA synthetase, class Ic
   1. PF00579 (tRNA-synt_1b)
      58 - 361
      Pfam
      PF00579 (tRNA-synt_1b)
2. IPR002307
   Tyrosine-tRNA ligase
   1. PR01040 (TRNASYNTHTYR)
      72 - 94
      PRINTS
      PR01040 (TRNASYNTHTYR)
      258 - 270
      PRINTS
      PR01040 (TRNASYNTHTYR)
      200 - 215
      PRINTS
      PR01040 (TRNASYNTHTYR)
      221 - 243
      PRINTS
      PR01040 (TRNASYNTHTYR)
   2. TIGR00234
      28 - 461
      UNKNOWN
      TIGR00234 (TIGR00234)
3. IPR024088
   Tyrosine-tRNA ligase, bacterial-type
   1. PTHR11766 (TYROSYL-...)
      30 - 461
      PANTHER
      PTHR11766 (TYROSYL-TRNA SYNTHETASE)
4. IPR024107
   Tyrosine-tRNA ligase, bacterial-type, type 1
   1. MF_02006 (Tyr_tRNA_...)
      27 - 461
      HAMAP
      MF_02006 (Tyr_tRNA_synth_type1)
5. IPR014729
   Rossmann-like alpha/beta/alpha sandwich fold
   1. G3DSA:3.40.50...
      19 - 274
      GENE3D
      G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
6. IPR002942
   RNA-binding S4 domain
   1. G3DSA:3.10.29...
      355 - 461
      GENE3D
      G3DSA:3.10.290.10 (G3DSA:3.10.290.10)

no IPR
Unintegrated signatures

1. G3DSA:1.10.24...
   275 - 354
   GENE3D
   G3DSA:1.10.240.10 (G3DSA:1.10.240.10)
2. PTHR11766:SF0 (SUBF...)
   30 - 461
   PANTHER
   PTHR11766:SF0 (SUBFAMILY NOT NAMED)
3. SSF52374 (Nucleotid...)
   30 - 361
   SUPERFAMILY
   SSF52374 (Nucleotidylyl transferase)
4. SSF55174 (Alpha-L R...)
   360 - 461
   SUPERFAMILY
   SSF55174 (Alpha-L RNA-binding motif)

### GO term prediction

#### Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation

#### Molecular Function

GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding

#### Cellular Component

GO:0005737 cytoplasm