Protein

## EMLSAP00000006629

Length
1,183 amino acids

### Protein family membership

- NMDA receptor (IPR001508)

### Domains and repeats

1. Domain
   83 - 431
   - Periplasmic binding protein-like I (IPR028082)
   474 - 539
   - Glutamate receptor, L-glutamate/glycine-binding (IPR019594)
2. Domain
   100 - 382
   - Extracellular ligand-binding receptor (IPR001828)
   489 - 828
   - Extracellular solute-binding protein, family 3 (IPR001638)
   874 - 902
   - Calmodulin-binding domain C0, NMDA receptor, NR1 subunit (IPR018882)
3. Domain
   466 - 863
   - Ionotropic glutamate receptor (IPR001320)

1 200 400 600 800 1000 1183

### Detailed signature matches

1. IPR001508
   NMDA receptor
   1. PR00177 (NMDARECEPTOR)
      852 - 876
      PRINTS
      PR00177 (NMDARECEPTOR)
      504 - 532
      PRINTS
      PR00177 (NMDARECEPTOR)
      594 - 619
      PRINTS
      PR00177 (NMDARECEPTOR)
      666 - 693
      PRINTS
      PR00177 (NMDARECEPTOR)
2. IPR028082
   Periplasmic binding protein-like I
   1. SSF53822 (Periplasm...)
      83 - 431
      SUPERFAMILY
      SSF53822 (Periplasmic binding protein-like I)
3. IPR001828
   Extracellular ligand-binding receptor
   1. PF01094 (ANF_receptor)
      100 - 382
      Pfam
      PF01094 (ANF_receptor)
4. IPR001320
   Ionotropic glutamate receptor
   1. PF00060 (Lig_chan)
      593 - 863
      Pfam
      PF00060 (Lig_chan)
   2. SM00079 (PBPe)
      466 - 830
      SMART
      SM00079 (PBPe)
5. IPR019594
   Glutamate receptor, L-glutamate/glycine-binding
   1. SM00918 (Lig_chan-G...)
      474 - 539
      SMART
      SM00918 (Lig_chan-Glu_bd)
6. IPR001638
   Extracellular solute-binding protein, family 3
   1. PF00497 (SBP_bac_3)
      489 - 828
      Pfam
      PF00497 (SBP_bac_3)
7. IPR018882
   Calmodulin-binding domain C0, NMDA receptor, NR1 subunit
   1. PF10562 (CaM_bdg_C0)
      874 - 902
      Pfam
      PF10562 (CaM_bdg_C0)

no IPR
Unintegrated signatures

1. G3DSA:1.10.28...
   607 - 689
   GENE3D
   G3DSA:1.10.287.70 (G3DSA:1.10.287.70)
2. G3DSA:3.40.19...
   435 - 606
   GENE3D
   G3DSA:3.40.190.10 (G3DSA:3.40.190.10)
   690 - 794
   GENE3D
   G3DSA:3.40.190.10 (G3DSA:3.40.190.10)
3. G3DSA:3.40.50...
   252 - 374
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
   50 - 166
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
4. PTHR18966 (IONOTROP...)
   95 - 910
   PANTHER
   PTHR18966 (IONOTROPIC GLUTAMATE RECEPTOR)
5. PTHR18966:SF41 (GLU...)
   95 - 910
   PANTHER
   PTHR18966:SF41 (GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1)
6. SSF53850 (Periplasm...)
   445 - 577
   SUPERFAMILY
   SSF53850 (Periplasmic binding protein-like II)
   695 - 828
   SUPERFAMILY
   SSF53850 (Periplasmic binding protein-like II)
7. SSF81324 (Voltage-g...)
   592 - 691
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
8. TMhelix
   593 - 612
   TMHMM
   TMhelix (TMhelix)
   636 - 655
   TMHMM
   TMhelix (TMhelix)
   854 - 876
   TMHMM
   TMhelix (TMhelix)
   670 - 692
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006810 transport
GO:0006811 ion transport

#### Molecular Function

GO:0004872 receptor activity
GO:0004970 ionotropic glutamate receptor activity
GO:0005215 transporter activity
GO:0005216 ion channel activity
GO:0005234 extracellular-glutamate-gated ion channel activity

#### Cellular Component

GO:0016020 membrane