Protein

## EMLSAP00000006186

Length
1,014 amino acids

### Protein family membership

- Fumarate lyase family (IPR000362)
  - Adenylosuccinate lyase (IPR004769)

### Domains and repeats

1. Domain
   191 - 588
   - Kinesin, motor domain (IPR001752)
   907 - 991
   - Adenylosuccinate lyase C-terminal (IPR019468)
2. Domain
   288 - 598
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
3. Domain
   581 - 837
   - Fumarase/histidase, N-terminal (IPR024083)
     - Fumarate lyase, N-terminal (IPR022761)
4. Domain
   585 - 992
   - L-Aspartase-like (IPR008948)

1 100 200 300 400 500 600 700 800 900 1014

### Detailed signature matches

1. IPR000362
   Fumarate lyase family
   1. PTHR11444 (ASPARTAT...)
      581 - 1,007
      PANTHER
      PTHR11444 (ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE)
2. IPR004769
   Adenylosuccinate lyase
   1. PTHR11444:SF2 (ADEN...)
      581 - 1,007
      PANTHER
      PTHR11444:SF2 (ADENYLOSUCCINATE LYASE)
   2. TIGR00928
      585 - 990
      UNKNOWN
      TIGR00928 (TIGR00928)
3. IPR001752
   Kinesin, motor domain
   1. G3DSA:3.40.85...
      281 - 580
      GENE3D
      G3DSA:3.40.850.10 (G3DSA:3.40.850.10)
   2. PS50067 (KINESIN_MO...)
      285 - 511
      PROSITE profiles
      PS50067 (KINESIN_MOTOR_DOMAIN2)
   3. PR00380 (KINESINHEAVY)
      450 - 467
      PRINTS
      PR00380 (KINESINHEAVY)
      481 - 499
      PRINTS
      PR00380 (KINESINHEAVY)
      327 - 348
      PRINTS
      PR00380 (KINESINHEAVY)
      530 - 551
      PRINTS
      PR00380 (KINESINHEAVY)
   4. PF00225 (Kinesin)
      279 - 579
      Pfam
      PF00225 (Kinesin)
   5. SM00129 (KISc)
      191 - 588
      SMART
      SM00129 (KISc)
4. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      288 - 598
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
5. IPR024083
   Fumarase/histidase, N-terminal
   1. G3DSA:1.10.27...
      581 - 638
      GENE3D
      G3DSA:1.10.275.10 (G3DSA:1.10.275.10)
6. IPR022761
   Fumarate lyase, N-terminal
   1. PF00206 (Lyase_1)
      583 - 837
      Pfam
      PF00206 (Lyase_1)
7. IPR008948
   L-Aspartase-like
   1. SSF48557 (L-asparta...)
      585 - 992
      SUPERFAMILY
      SSF48557 (L-aspartase-like)
8. IPR019468
   Adenylosuccinate lyase C-terminal
   1. SM00998 (ADSL_C)
      907 - 991
      SMART
      SM00998 (ADSL_C)
   2. PF10397 (ADSL_C)
      908 - 990
      Pfam
      PF10397 (ADSL_C)
9. IPR020557
   Fumarate lyase, conserved site
   1. PS00163 (FUMARATE_L...)
      818 - 827
      PROSITE patterns
      PS00163 (FUMARATE_LYASES)

no IPR
Unintegrated signatures

1. Coil
   78 - 152
   COILS
   Coil (Coil)
   166 - 218
   COILS
   Coil (Coil)
2. G3DSA:1.20.20...
   639 - 988
   GENE3D
   G3DSA:1.20.200.10 (G3DSA:1.20.200.10)

### GO term prediction

#### Biological Process

GO:0007018 microtubule-based movement
GO:0009152 purine ribonucleotide biosynthetic process

#### Molecular Function

GO:0003777 microtubule motor activity
GO:0003824 catalytic activity
GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
GO:0005524 ATP binding
GO:0008017 microtubule binding

#### Cellular Component

None predicted.