Protein

## EMLSAP00000000157

Length
483 amino acids

### Protein family membership

- Peptidase M10A (IPR021190)
  - Metalloendoproteinase (IPR028737)

### Domains and repeats

1. Domain
   40 - 102
   - Peptidoglycan binding-like (IPR002477)
   116 - 264
   - Peptidase, metallopeptidase (IPR006026)
     - Peptidase M10, metallopeptidase (IPR001818)
   317 - 476
   - Hemopexin-like domain (IPR000585)
2. Domain
   41 - 266
   - Metallopeptidase, catalytic domain (IPR024079)
3. Repeat
   382 - 431
   - Hemopexin-like repeats (IPR018487)
4. Repeat
   430 - 478
   - Hemopexin-like repeats (IPR018487)

1 50 100 150 200 250 300 350 400 450 483

### Detailed signature matches

1. IPR021190
   Peptidase M10A
   1. PTHR10201 (MATRIX M...)
      4 - 476
      PANTHER
      PTHR10201 (MATRIX METALLOPROTEINASE)
   2. PR00138 (MATRIXIN)
      158 - 186
      PRINTS
      PR00138 (MATRIXIN)
      218 - 243
      PRINTS
      PR00138 (MATRIXIN)
      250 - 263
      PRINTS
      PR00138 (MATRIXIN)
      92 - 105
      PRINTS
      PR00138 (MATRIXIN)
      134 - 149
      PRINTS
      PR00138 (MATRIXIN)
2. IPR028737
   Metalloendoproteinase
   1. PTHR10201:SF102 (SU...)
      4 - 476
      PANTHER
      PTHR10201:SF102 (SUBFAMILY NOT NAMED)
3. IPR002477
   Peptidoglycan binding-like
   1. SSF47090 (PGBD-like)
      40 - 102
      SUPERFAMILY
      SSF47090 (PGBD-like)
4. IPR024079
   Metallopeptidase, catalytic domain
   1. G3DSA:3.40.39...
      41 - 266
      GENE3D
      G3DSA:3.40.390.10 (G3DSA:3.40.390.10)
5. IPR006026
   Peptidase, metallopeptidase
   1. SM00235 (ZnMc)
      116 - 264
      SMART
      SM00235 (ZnMc)
6. IPR001818
   Peptidase M10, metallopeptidase
   1. PF00413 (Peptidase_M10)
      126 - 262
      Pfam
      PF00413 (Peptidase_M10)
7. IPR000585
   Hemopexin-like domain
   1. G3DSA:2.110.1...
      353 - 476
      GENE3D
      G3DSA:2.110.10.10 (G3DSA:2.110.10.10)
   2. SSF50923 (Hemopexin...)
      317 - 469
      SUPERFAMILY
      SSF50923 (Hemopexin-like domain)
8. IPR018487
   Hemopexin-like repeats
   1. SM00120 (HX)
      385 - 431
      SMART
      SM00120 (HX)
      433 - 478
      SMART
      SM00120 (HX)
   2. PF00045 (Hemopexin)
      433 - 478
      Pfam
      PF00045 (Hemopexin)
      385 - 431
      Pfam
      PF00045 (Hemopexin)
   3. PS51642 (HEMOPEXIN_2)
      430 - 477
      PROSITE profiles
      PS51642 (HEMOPEXIN_2)
      382 - 429
      PROSITE profiles
      PS51642 (HEMOPEXIN_2)
9. IPR021158
   Peptidase M10A, cysteine switch, zinc binding site
   1. PS00546 (CYSTEINE_S...)
      95 - 102
      PROSITE patterns
      PS00546 (CYSTEINE_SWITCH)

no IPR
Unintegrated signatures

1. SSF55486 (Metallopr...)
   112 - 265
   SUPERFAMILY
   SSF55486 (Metalloproteases ("zincins"), catalytic domain)
2. SignalP-TM
   1 - 27
   SignalP Gram+ prok
   SignalP-TM (SignalP-TM)
3. SignalP-noTM
   1 - 20
   SignalP euk
   SignalP-noTM (SignalP-noTM)
4. TMhelix
   5 - 24
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis

#### Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding

#### Cellular Component

GO:0031012 extracellular matrix