Protein

## EMLSAP00000003002

Length
900 amino acids

### Protein family membership

- DNA helicase, ATP-dependent, RecQ type (IPR004589)

### Domains and repeats

1. Domain
   54 - 250
   - Helicase, superfamily 1/2, ATP-binding domain (IPR014001)
     - DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
   258 - 420
   - Helicase, C-terminal (IPR001650)
   467 - 576
   - RQC domain (IPR018982)
   607 - 684
   - HRDC-like (IPR010997)
2. Domain
   98 - 389
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   603 - 683
   - HRDC domain (IPR002121)
3. Domain
   384 - 571
   - Winged helix-turn-helix DNA-binding domain (IPR011991)

1 100 200 300 400 500 600 700 800 900 900

### Detailed signature matches

1. IPR004589
   DNA helicase, ATP-dependent, RecQ type
   1. TIGR00614
      47 - 518
      UNKNOWN
      TIGR00614 (TIGR00614)
2. IPR014001
   Helicase, superfamily 1/2, ATP-binding domain
   1. SM00487 (DEXDc)
      54 - 250
      SMART
      SM00487 (DEXDc)
   2. PS51192 (HELICASE_A...)
      67 - 234
      PROSITE profiles
      PS51192 (HELICASE_ATP_BIND_1)
3. IPR011545
   DNA/RNA helicase, DEAD/DEAH box type, N-terminal
   1. PF00270 (DEAD)
      60 - 222
      Pfam
      PF00270 (DEAD)
4. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      98 - 389
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
5. IPR001650
   Helicase, C-terminal
   1. PF00271 (Helicase_C)
      296 - 370
      Pfam
      PF00271 (Helicase_C)
   2. SM00490 (HELICc)
      289 - 370
      SMART
      SM00490 (HELICc)
   3. PS51194 (HELICASE_CTER)
      258 - 420
      PROSITE profiles
      PS51194 (HELICASE_CTER)
6. IPR011991
   Winged helix-turn-helix DNA-binding domain
   1. G3DSA:1.10.10.10
      384 - 571
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
7. IPR018982
   RQC domain
   1. PF09382 (RQC)
      467 - 569
      Pfam
      PF09382 (RQC)
   2. SM00956 (RQC)
      467 - 576
      SMART
      SM00956 (RQC)
8. IPR002121
   HRDC domain
   1. G3DSA:1.10.15...
      612 - 678
      GENE3D
      G3DSA:1.10.150.80 (G3DSA:1.10.150.80)
   2. PF00570 (HRDC)
      613 - 671
      Pfam
      PF00570 (HRDC)
   3. PS50967 (HRDC)
      603 - 683
      PROSITE profiles
      PS50967 (HRDC)
9. IPR010997
   HRDC-like
   1. SSF47819 (HRDC-like)
      607 - 684
      SUPERFAMILY
      SSF47819 (HRDC-like)

no IPR
Unintegrated signatures

1. G3DSA:3.40.50...
   42 - 230
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   238 - 383
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
2. PF14493 (HTH_40)
   705 - 799
   Pfam
   PF14493 (HTH_40)
3. PTHR13710 (DNA HELI...)
   36 - 747
   PANTHER
   PTHR13710 (DNA HELICASE RECQ FAMILY MEMBER)
4. PTHR13710:SF11 (DNA...)
   36 - 747
   PANTHER
   PTHR13710:SF11 (DNA HELICASE RECQ)
5. SSF46785 ("Winged h...)
   462 - 577
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)

### GO term prediction

#### Biological Process

GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0044237 cellular metabolic process

#### Molecular Function

GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003824 catalytic activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity

#### Cellular Component

GO:0005622 intracellular