Protein

## EMLSAP00000001950

Length
1,303 amino acids

### Protein family membership

- Patched (IPR003392)

### Domains and repeats

1. Domain
   591 - 756
   - Sterol-sensing domain (IPR000731)

1 200 400 600 800 1000 1200 1303

### Detailed signature matches

1. IPR003392
   Patched
   1. PF02460 (Patched)
      1,139 - 1,257
      Pfam
      PF02460 (Patched)
2. IPR000731
   Sterol-sensing domain
   1. PS50156 (SSD)
      591 - 756
      PROSITE profiles
      PS50156 (SSD)

no IPR
Unintegrated signatures

1. G3DSA:1.20.16...
   1,141 - 1,252
   GENE3D
   G3DSA:1.20.1640.10 (G3DSA:1.20.1640.10)
   554 - 761
   GENE3D
   G3DSA:1.20.1640.10 (G3DSA:1.20.1640.10)
2. PF12349 (Sterol-sen...)
   620 - 773
   Pfam
   PF12349 (Sterol-sensing)
3. PTHR10796 (PATCHED-...)
   37 - 1,259
   PANTHER
   PTHR10796 (PATCHED-RELATED)
4. PTHR10796:SF35 (NIE...)
   37 - 1,259
   PANTHER
   PTHR10796:SF35 (NIEMANN-PICK C1)
5. SSF82866 (Multidrug...)
   1,142 - 1,249
   SUPERFAMILY
   SSF82866 (Multidrug efflux transporter AcrB transmembrane domain)
   556 - 756
   SUPERFAMILY
   SSF82866 (Multidrug efflux transporter AcrB transmembrane domain)
6. SignalP-noTM
   1 - 18
   SignalP euk
   SignalP-noTM (SignalP-noTM)
7. TMhelix
   1,194 - 1,216
   TMHMM
   TMhelix (TMhelix)
   1,168 - 1,190
   TMHMM
   TMhelix (TMhelix)
   377 - 399
   TMHMM
   TMhelix (TMhelix)
   592 - 614
   TMHMM
   TMhelix (TMhelix)
   653 - 675
   TMHMM
   TMhelix (TMhelix)
   268 - 290
   TMHMM
   TMhelix (TMhelix)
   804 - 823
   TMHMM
   TMhelix (TMhelix)
   732 - 754
   TMHMM
   TMhelix (TMhelix)
   627 - 649
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0008158 hedgehog receptor activity

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane