Protein

## EMLSAP00000004851

Length
669 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   1 - 567
   - Cullin, N-terminal (IPR001373)
2. Domain
   1 - 272
   - Cullin repeat-like-containing domain (IPR016159)
   274 - 579
   - Cullin homology (IPR016158)
3. Domain
   497 - 565
   - Winged helix-turn-helix DNA-binding domain (IPR011991)
   566 - 669
   - Winged helix-turn-helix DNA-binding domain (IPR011991)
     - Cullin protein, neddylation domain (IPR019559)

1 100 200 300 400 500 600 669

### Detailed signature matches

1. IPR016159
   Cullin repeat-like-containing domain
   1. SSF74788 (Cullin re...)
      1 - 272
      SUPERFAMILY
      SSF74788 (Cullin repeat-like)
2. IPR001373
   Cullin, N-terminal
   1. PF00888 (Cullin)
      1 - 567
      Pfam
      PF00888 (Cullin)
3. IPR016158
   Cullin homology
   1. PS50069 (CULLIN_2)
      274 - 536
      PROSITE profiles
      PS50069 (CULLIN_2)
   2. SSF75632 (Cullin ho...)
      489 - 579
      SUPERFAMILY
      SSF75632 (Cullin homology domain)
      274 - 456
      SUPERFAMILY
      SSF75632 (Cullin homology domain)
   3. SM00182 (CULLIN)
      304 - 454
      SMART
      SM00182 (CULLIN)
4. IPR011991
   Winged helix-turn-helix DNA-binding domain
   1. G3DSA:1.10.10.10
      566 - 669
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
      497 - 565
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
5. IPR019559
   Cullin protein, neddylation domain
   1. SM00884 (Cullin_Nedd8)
      596 - 663
      SMART
      SM00884 (Cullin_Nedd8)
   2. PF10557 (Cullin_Nedd8)
      596 - 662
      Pfam
      PF10557 (Cullin_Nedd8)
6. IPR016157
   Cullin, conserved site
   1. PS01256 (CULLIN_1)
      642 - 669
      PROSITE patterns
      PS01256 (CULLIN_1)

no IPR
Unintegrated signatures

1. Coil
   119 - 140
   COILS
   Coil (Coil)
2. G3DSA:1.20.13...
   278 - 386
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
   2 - 38
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
   42 - 161
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
   163 - 277
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
3. G3DSA:4.10.10...
   391 - 458
   GENE3D
   G3DSA:4.10.1030.10 (G3DSA:4.10.1030.10)
4. PTHR11932 (CULLIN)
   1 - 669
   PANTHER
   PTHR11932 (CULLIN)
5. PTHR11932:SF58 (CUL...)
   1 - 669
   PANTHER
   PTHR11932:SF58 (CULLIN FAMILY PROTEIN)
6. SSF46785 ("Winged h...)
   582 - 669
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)

### GO term prediction

#### Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

#### Molecular Function

GO:0031625 ubiquitin protein ligase binding

#### Cellular Component

GO:0031461 cullin-RING ubiquitin ligase complex