Protein

## EMLSAP00000003455

Length
378 amino acids

### Protein family membership

- Potassium channel, calcium-activated, SK (IPR015449)

### Domains and repeats

1. Domain
   5 - 70
   - Two pore domain potassium channel domain (IPR013099)
2. Domain
   68 - 161
   - Calmodulin-binding domain (IPR004178)

1 50 100 150 200 250 300 350 378

### Detailed signature matches

1. IPR015449
   Potassium channel, calcium-activated, SK
   1. PTHR10153 (SMALL CO...)
      9 - 207
      PANTHER
      PTHR10153 (SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL)
2. IPR013099
   Two pore domain potassium channel domain
   1. PF07885 (Ion_trans_2)
      5 - 70
      Pfam
      PF07885 (Ion_trans_2)
3. IPR004178
   Calmodulin-binding domain
   1. SSF81327 (Small-con...)
      68 - 159
      SUPERFAMILY
      SSF81327 (Small-conductance potassium channel)
   2. PF02888 (CaMBD)
      85 - 160
      Pfam
      PF02888 (CaMBD)
   3. SM01053 (CaMBD)
      85 - 161
      SMART
      SM01053 (CaMBD)

no IPR
Unintegrated signatures

1. Coil
   166 - 187
   COILS
   Coil (Coil)
2. G3DSA:1.10.28...
   5 - 78
   GENE3D
   G3DSA:1.10.287.70 (G3DSA:1.10.287.70)
   85 - 165
   GENE3D
   G3DSA:1.10.287.70 (G3DSA:1.10.287.70)
3. PTHR10153:SF25 (SMA...)
   9 - 207
   PANTHER
   PTHR10153:SF25 (SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN)
4. SSF81324 (Voltage-g...)
   5 - 71
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
5. TMhelix
   15 - 37
   TMHMM
   TMhelix (TMhelix)
   44 - 66
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006813 potassium ion transport

#### Molecular Function

GO:0005516 calmodulin binding
GO:0015269 calcium-activated potassium channel activity
GO:0016286 small conductance calcium-activated potassium channel activity

#### Cellular Component

GO:0016021 integral component of membrane