Protein

## EMLSAP00000002448

Length
1,579 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   124 - 322
   - Helicase, superfamily 1/2, ATP-binding domain (IPR014001)
     - DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
   359 - 545
   - Helicase, C-terminal (IPR001650)
   567 - 667
   - Helicase-associated domain (IPR007502)
   918 - 1,037
   - Tudor domain (IPR002999)
2. Domain
   139 - 288
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   345 - 515
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 200 400 600 800 1000 1200 1400 1579

### Detailed signature matches

1. IPR014001
   Helicase, superfamily 1/2, ATP-binding domain
   1. SM00487 (DEXDc)
      124 - 322
      SMART
      SM00487 (DEXDc)
   2. PS51192 (HELICASE_A...)
      136 - 303
      PROSITE profiles
      PS51192 (HELICASE_ATP_BIND_1)
2. IPR011545
   DNA/RNA helicase, DEAD/DEAH box type, N-terminal
   1. PF00270 (DEAD)
      135 - 286
      Pfam
      PF00270 (DEAD)
3. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      139 - 288
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      345 - 515
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
4. IPR001650
   Helicase, C-terminal
   1. PF00271 (Helicase_C)
      411 - 503
      Pfam
      PF00271 (Helicase_C)
   2. PS51194 (HELICASE_CTER)
      359 - 545
      PROSITE profiles
      PS51194 (HELICASE_CTER)
   3. SM00490 (HELICc)
      392 - 504
      SMART
      SM00490 (HELICc)
5. IPR007502
   Helicase-associated domain
   1. SM00847 (HA2)
      567 - 667
      SMART
      SM00847 (HA2)
   2. PF04408 (HA2)
      568 - 647
      Pfam
      PF04408 (HA2)
6. IPR002999
   Tudor domain
   1. SM00333 (TUDOR)
      970 - 1,032
      SMART
      SM00333 (TUDOR)
   2. PS50304 (TUDOR)
      974 - 1,034
      PROSITE profiles
      PS50304 (TUDOR)
   3. PF00567 (TUDOR)
      918 - 1,037
      Pfam
      PF00567 (TUDOR)

no IPR
Unintegrated signatures

1. G3DSA:2.30.30...
   954 - 1,026
   GENE3D
   G3DSA:2.30.30.140 (G3DSA:2.30.30.140)
2. G3DSA:3.40.50...
   364 - 515
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   126 - 286
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PTHR18934 (ATP-DEPE...)
   126 - 762
   PANTHER
   PTHR18934 (ATP-DEPENDENT RNA HELICASE)
4. SSF63748 (Tudor/PWW...)
   942 - 1,053
   SUPERFAMILY
   SSF63748 (Tudor/PWWP/MBT)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity

#### Cellular Component

None predicted.