Protein

## EMLSAP00000003185

Length
498 amino acids

### Protein family membership

- Neurotransmitter-gated ion-channel (IPR006201)
  - Gamma-aminobutyric acid A receptor (IPR006028)

### Domains and repeats

1. Domain
   39 - 249
   - Neurotransmitter-gated ion-channel ligand-binding (IPR006202)
   253 - 482
   - Neurotransmitter-gated ion-channel transmembrane domain (IPR006029)

1 50 100 150 200 250 300 350 400 450 498

### Detailed signature matches

1. IPR006201
   Neurotransmitter-gated ion-channel
   1. PTHR18945 (NEUROTRA...)
      1 - 484
      PANTHER
      PTHR18945 (NEUROTRANSMITTER GATED ION CHANNEL)
   2. PR00252 (NRIONCHANNEL)
      120 - 131
      PRINTS
      PR00252 (NRIONCHANNEL)
      245 - 257
      PRINTS
      PR00252 (NRIONCHANNEL)
      166 - 180
      PRINTS
      PR00252 (NRIONCHANNEL)
      78 - 94
      PRINTS
      PR00252 (NRIONCHANNEL)
2. IPR006028
   Gamma-aminobutyric acid A receptor
   1. PR00253 (GABAARECEPTR)
      254 - 274
      PRINTS
      PR00253 (GABAARECEPTR)
      314 - 335
      PRINTS
      PR00253 (GABAARECEPTR)
      461 - 481
      PRINTS
      PR00253 (GABAARECEPTR)
      280 - 301
      PRINTS
      PR00253 (GABAARECEPTR)
3. IPR006202
   Neurotransmitter-gated ion-channel ligand-binding
   1. PF02931 (Neur_chan_LBD)
      40 - 200
      Pfam
      PF02931 (Neur_chan_LBD)
   2. SSF63712 (Nicotinic...)
      39 - 249
      SUPERFAMILY
      SSF63712 (Nicotinic receptor ligand binding domain-like)
   3. G3DSA:2.70.17...
      57 - 249
      GENE3D
      G3DSA:2.70.170.10 (G3DSA:2.70.170.10)
4. IPR006029
   Neurotransmitter-gated ion-channel transmembrane domain
   1. SSF90112 (Neurotran...)
      253 - 482
      SUPERFAMILY
      SSF90112 (Neurotransmitter-gated ion-channel transmembrane pore)
   2. PF02932 (Neur_chan_...)
      259 - 478
      Pfam
      PF02932 (Neur_chan_memb)
5. IPR018000
   Neurotransmitter-gated ion-channel, conserved site
   1. PS00236 (NEUROTR_IO...)
      166 - 180
      PROSITE patterns
      PS00236 (NEUROTR_ION_CHANNEL)

no IPR
Unintegrated signatures

1. G3DSA:1.20.58...
   252 - 349
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
   458 - 483
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
2. PTHR18945:SF201 (GA...)
   1 - 484
   PANTHER
   PTHR18945:SF201 (GAMMA-AMINOBUTYRIC ACID A RECEPTOR BETA-RELATED)
3. SignalP-noTM
   1 - 23
   SignalP euk
   SignalP-noTM (SignalP-noTM)
4. TMhelix
   311 - 333
   TMHMM
   TMhelix (TMhelix)
   279 - 301
   TMHMM
   TMhelix (TMhelix)
   250 - 272
   TMHMM
   TMhelix (TMhelix)
   461 - 480
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006810 transport
GO:0006811 ion transport

#### Molecular Function

GO:0005230 extracellular ligand-gated ion channel activity

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane