Protein

## EMLSAP00000012935

Length
611 amino acids

### Protein family membership

- Cortactin (IPR015503)

### Domains and repeats

1. Domain
   554 - 611
   - Src homology-3 domain (IPR001452)
2. Repeat
   64 - 103
   - Hs1/Cortactin (IPR003134)
   138 - 175
   - Hs1/Cortactin (IPR003134)
   249 - 285
   - Hs1/Cortactin (IPR003134)
3. Repeat
   101 - 138
   - Hs1/Cortactin (IPR003134)
   212 - 251
   - Hs1/Cortactin (IPR003134)
4. Repeat
   175 - 212
   - Hs1/Cortactin (IPR003134)

1 100 200 300 400 500 611

### Detailed signature matches

1. IPR015503
   Cortactin
   1. PTHR10829:SF4 (SRC ...)
      1 - 611
      PANTHER
      PTHR10829:SF4 (SRC SUBSTRATE CORTACTIN)
2. IPR001452
   Src homology-3 domain
   1. SM00326 (SH3)
      557 - 611
      SMART
      SM00326 (SH3)
   2. PR00452 (SH3DOMAIN)
      571 - 586
      PRINTS
      PR00452 (SH3DOMAIN)
      588 - 597
      PRINTS
      PR00452 (SH3DOMAIN)
      557 - 567
      PRINTS
      PR00452 (SH3DOMAIN)
      599 - 611
      PRINTS
      PR00452 (SH3DOMAIN)
   3. SSF50044 (SH3-domain)
      558 - 611
      SUPERFAMILY
      SSF50044 (SH3-domain)
   4. PS50002 (SH3)
      554 - 611
      PROSITE profiles
      PS50002 (SH3)
3. IPR003134
   Hs1/Cortactin
   1. PF02218 (HS1_rep)
      215 - 251
      Pfam
      PF02218 (HS1_rep)
      104 - 138
      Pfam
      PF02218 (HS1_rep)
      252 - 271
      Pfam
      PF02218 (HS1_rep)
      67 - 103
      Pfam
      PF02218 (HS1_rep)
      178 - 212
      Pfam
      PF02218 (HS1_rep)
      141 - 175
      Pfam
      PF02218 (HS1_rep)
   2. PS51090 (CORTACTIN)
      175 - 211
      PROSITE profiles
      PS51090 (CORTACTIN)
      64 - 100
      PROSITE profiles
      PS51090 (CORTACTIN)
      249 - 285
      PROSITE profiles
      PS51090 (CORTACTIN)
      212 - 248
      PROSITE profiles
      PS51090 (CORTACTIN)
      138 - 174
      PROSITE profiles
      PS51090 (CORTACTIN)
      101 - 137
      PROSITE profiles
      PS51090 (CORTACTIN)

no IPR
Unintegrated signatures

1. G3DSA:2.30.30.40
   558 - 611
   GENE3D
   G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
2. PF14604 (SH3_9)
   561 - 609
   Pfam
   PF14604 (SH3_9)
3. PR00499 (P67PHOX)
   559 - 579
   PRINTS
   PR00499 (P67PHOX)
   595 - 608
   PRINTS
   PR00499 (P67PHOX)
   579 - 595
   PRINTS
   PR00499 (P67PHOX)
4. PTHR10829 (CORTACTI...)
   1 - 611
   PANTHER
   PTHR10829 (CORTACTIN AND DREBRIN)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0005515 protein binding

#### Cellular Component

GO:0001726 ruffle
GO:0005856 cytoskeleton
GO:0030027 lamellipodium