Protein

## EMLSAP00000012442

Length
527 amino acids

### Protein family membership

- Peptidase S1A, chymotrypsin-type (IPR001314)

### Domains and repeats

1. Domain
   123 - 200
   - Apple domain (IPR000177)
   277 - 527
   - Trypsin-like cysteine/serine peptidase domain (IPR009003)
     - Peptidase S1 (IPR001254)
2. Domain
   223 - 281
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)

1 50 100 150 200 250 300 350 400 450 500 527

### Detailed signature matches

1. IPR001314
   Peptidase S1A, chymotrypsin-type
   1. PR00722 (CHYMOTRYPSIN)
      472 - 484
      PRINTS
      PR00722 (CHYMOTRYPSIN)
      381 - 395
      PRINTS
      PR00722 (CHYMOTRYPSIN)
      322 - 337
      PRINTS
      PR00722 (CHYMOTRYPSIN)
2. IPR000177
   Apple domain
   1. SM00223 (APPLE)
      123 - 200
      SMART
      SM00223 (APPLE)
3. IPR013806
   Kringle-like fold
   1. SSF57440 (Kringle-like)
      224 - 264
      SUPERFAMILY
      SSF57440 (Kringle-like)
4. IPR000562
   Fibronectin, type II, collagen-binding
   1. G3DSA:2.10.10.10
      223 - 278
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
   2. PF00040 (fn2)
      235 - 265
      Pfam
      PF00040 (fn2)
   3. SM00059 (FN2)
      228 - 281
      SMART
      SM00059 (FN2)
5. IPR009003
   Trypsin-like cysteine/serine peptidase domain
   1. SSF50494 (Trypsin-l...)
      277 - 526
      SUPERFAMILY
      SSF50494 (Trypsin-like serine proteases)
6. IPR001254
   Peptidase S1
   1. PF00089 (Trypsin)
      292 - 523
      Pfam
      PF00089 (Trypsin)
   2. SM00020 (Tryp_SPc)
      291 - 523
      SMART
      SM00020 (Tryp_SPc)
   3. PS50240 (TRYPSIN_DOM)
      292 - 527
      PROSITE profiles
      PS50240 (TRYPSIN_DOM)
7. IPR018114
   Peptidase S1, trypsin family, active site
   1. PS00135 (TRYPSIN_SER)
      473 - 484
      PROSITE patterns
      PS00135 (TRYPSIN_SER)
   2. PS00134 (TRYPSIN_HIS)
      332 - 337
      PROSITE patterns
      PS00134 (TRYPSIN_HIS)

no IPR
Unintegrated signatures

1. G3DSA:2.40.10.10
   292 - 327
   GENE3D
   G3DSA:2.40.10.10 (G3DSA:2.40.10.10)
   396 - 515
   GENE3D
   G3DSA:2.40.10.10 (G3DSA:2.40.10.10)
   328 - 395
   GENE3D
   G3DSA:2.40.10.10 (G3DSA:2.40.10.10)
2. G3DSA:3.50.4.10
   118 - 201
   GENE3D
   G3DSA:3.50.4.10 (G3DSA:3.50.4.10)
3. PF14295 (PAN_4)
   128 - 180
   Pfam
   PF14295 (PAN_4)
4. PTHR24268 (FAMILY N...)
   280 - 526
   PANTHER
   PTHR24268 (FAMILY NOT NAMED)
5. PTHR24268:SF28 (SUB...)
   280 - 526
   PANTHER
   PTHR24268:SF28 (SUBFAMILY NOT NAMED)
6. SSF57414 (Hairpin l...)
   120 - 200
   SUPERFAMILY
   SSF57414 (Hairpin loop containing domain-like)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis
GO:0007596 blood coagulation

#### Molecular Function

GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding

#### Cellular Component

GO:0005576 extracellular region