Protein

## EMLSAP00000002259

Length
704 amino acids

### Protein family membership

- Inhibin, alpha subunit (IPR002405)

### Domains and repeats

1. Domain
   46 - 278
   - Transforming growth factor-beta, N-terminal (IPR001111)
   321 - 454
   - Transforming growth factor-beta, C-terminal (IPR001839)
   487 - 589
   - Winged helix-turn-helix DNA-binding domain (IPR011991)
     - Transcription factor, fork head (IPR001766)

1 100 200 300 400 500 600 704

### Detailed signature matches

1. IPR002405
   Inhibin, alpha subunit
   1. PR00669 (INHIBINA)
      349 - 366
      PRINTS
      PR00669 (INHIBINA)
      366 - 383
      PRINTS
      PR00669 (INHIBINA)
2. IPR001111
   Transforming growth factor-beta, N-terminal
   1. PF00688 (TGFb_prope...)
      46 - 278
      Pfam
      PF00688 (TGFb_propeptide)
3. IPR001839
   Transforming growth factor-beta, C-terminal
   1. PS51362 (TGF_BETA_2)
      321 - 454
      PROSITE profiles
      PS51362 (TGF_BETA_2)
   2. PF00019 (TGF_beta)
      347 - 431
      Pfam
      PF00019 (TGF_beta)
   3. SM00204 (TGFB)
      349 - 430
      SMART
      SM00204 (TGFB)
4. IPR011991
   Winged helix-turn-helix DNA-binding domain
   1. G3DSA:1.10.10.10
      487 - 580
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
5. IPR001766
   Transcription factor, fork head
   1. PS50039 (FORK_HEAD_3)
      494 - 588
      PROSITE profiles
      PS50039 (FORK_HEAD_3)
   2. PF00250 (Fork_head)
      494 - 589
      Pfam
      PF00250 (Fork_head)
   3. SM00339 (FH)
      492 - 582
      SMART
      SM00339 (FH)
   4. PR00053 (FORKHEAD)
      538 - 555
      PRINTS
      PR00053 (FORKHEAD)
      494 - 507
      PRINTS
      PR00053 (FORKHEAD)
      515 - 532
      PRINTS
      PR00053 (FORKHEAD)
6. IPR017948
   Transforming growth factor beta, conserved site
   1. PS00250 (TGF_BETA_1)
      367 - 382
      PROSITE patterns
      PS00250 (TGF_BETA_1)
7. IPR018122
   Transcription factor, fork head, conserved site
   1. PS00657 (FORK_HEAD_1)
      494 - 507
      PROSITE patterns
      PS00657 (FORK_HEAD_1)
   2. PS00658 (FORK_HEAD_2)
      538 - 544
      PROSITE patterns
      PS00658 (FORK_HEAD_2)

no IPR
Unintegrated signatures

1. G3DSA:2.10.90.10
   344 - 430
   GENE3D
   G3DSA:2.10.90.10 (G3DSA:2.10.90.10)
2. PTHR11829 (FORKHEAD...)
   494 - 691
   PANTHER
   PTHR11829 (FORKHEAD BOX PROTEIN)
3. PTHR11829:SF83 (FOR...)
   494 - 691
   PANTHER
   PTHR11829:SF83 (FORK HEAD DOMAIN-CONTAINING PROTEIN FD3)
4. SSF46785 ("Winged h...)
   493 - 588
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)
5. SSF57501 (Cystine-k...)
   343 - 429
   SUPERFAMILY
   SSF57501 (Cystine-knot cytokines)
6. SignalP-noTM
   1 - 23
   SignalP euk
   SignalP-noTM (SignalP-noTM)

### GO term prediction

#### Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0040007 growth

#### Molecular Function

GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008083 growth factor activity
GO:0043565 sequence-specific DNA binding

#### Cellular Component

GO:0005576 extracellular region