Protein

## EMLSAP00000011472

Length
638 amino acids

### Protein family membership

- G protein-coupled receptor, rhodopsin-like (IPR000276)
  - Histamine H1 receptor (IPR000921)
  - Muscarinic acetylcholine receptor family (IPR000995)

### Domains and repeats

1. Domain
   57 - 599
   - GPCR, rhodopsin-like, 7TM (IPR017452)

1 100 200 300 400 500 638

### Detailed signature matches

1. IPR000276
   G protein-coupled receptor, rhodopsin-like
   1. PS00237 (G_PROTEIN_...)
      126 - 142
      PROSITE patterns
      PS00237 (G_PROTEIN_RECEP_F1_1)
   2. PF00001 (7tm_1)
      57 - 599
      Pfam
      PF00001 (7tm_1)
   3. PR00237 (GPCRRHODOPSN)
      205 - 228
      PRINTS
      PR00237 (GPCRRHODOPSN)
      541 - 565
      PRINTS
      PR00237 (GPCRRHODOPSN)
      75 - 96
      PRINTS
      PR00237 (GPCRRHODOPSN)
      120 - 142
      PRINTS
      PR00237 (GPCRRHODOPSN)
      156 - 177
      PRINTS
      PR00237 (GPCRRHODOPSN)
      581 - 607
      PRINTS
      PR00237 (GPCRRHODOPSN)
2. IPR000921
   Histamine H1 receptor
   1. PTHR24249:SF56 (HIS...)
      1 - 625
      PANTHER
      PTHR24249:SF56 (HISTAMINE H1 RECEPTOR)
3. IPR000995
   Muscarinic acetylcholine receptor family
   1. PR00243 (MUSCARINICR)
      571 - 589
      PRINTS
      PR00243 (MUSCARINICR)
      121 - 130
      PRINTS
      PR00243 (MUSCARINICR)
      140 - 154
      PRINTS
      PR00243 (MUSCARINICR)
      602 - 616
      PRINTS
      PR00243 (MUSCARINICR)
4. IPR017452
   GPCR, rhodopsin-like, 7TM
   1. PS50262 (G_PROTEIN_...)
      57 - 599
      PROSITE profiles
      PS50262 (G_PROTEIN_RECEP_F1_2)

no IPR
Unintegrated signatures

1. G3DSA:1.20.10...
   520 - 626
   GENE3D
   G3DSA:1.20.1070.10 (G3DSA:1.20.1070.10)
   41 - 241
   GENE3D
   G3DSA:1.20.1070.10 (G3DSA:1.20.1070.10)
2. PTHR24249 (HISTAMIN...)
   1 - 625
   PANTHER
   PTHR24249 (HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR)
3. SSF81321 (Family A ...)
   40 - 235
   SUPERFAMILY
   SSF81321 (Family A G protein-coupled receptor-like)
   530 - 622
   SUPERFAMILY
   SSF81321 (Family A G protein-coupled receptor-like)
4. TMhelix
   157 - 179
   TMHMM
   TMhelix (TMhelix)
   546 - 568
   TMHMM
   TMhelix (TMhelix)
   34 - 56
   TMHMM
   TMhelix (TMhelix)
   206 - 228
   TMHMM
   TMhelix (TMhelix)
   583 - 602
   TMHMM
   TMhelix (TMhelix)
   114 - 136
   TMHMM
   TMhelix (TMhelix)
   77 - 99
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0007186 G-protein coupled receptor signaling pathway
GO:0043114 regulation of vascular permeability
GO:0045907 positive regulation of vasoconstriction
GO:0048245 eosinophil chemotaxis

#### Molecular Function

GO:0004930 G-protein coupled receptor activity
GO:0004969 histamine receptor activity
GO:0016907 G-protein coupled acetylcholine receptor activity

#### Cellular Component

GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane