Protein

## EMLSAP00000011063

Length
368 amino acids

### Protein family membership

- Isocitrate and isopropylmalate dehydrogenases family (IPR001804)
  - Isocitrate dehydrogenase NAD-dependent (IPR004434)

### Domains and repeats

1. Domain
   33 - 367
   - Isopropylmalate dehydrogenase-like domain (IPR024084)

1 50 100 150 200 250 300 368

### Detailed signature matches

1. IPR001804
   Isocitrate and isopropylmalate dehydrogenases family
   1. PTHR11835 (DECARBOX...)
      33 - 368
      PANTHER
      PTHR11835 (DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE)
2. IPR004434
   Isocitrate dehydrogenase NAD-dependent
   1. TIGR00175
      34 - 367
      UNKNOWN
      TIGR00175 (TIGR00175)
3. IPR024084
   Isopropylmalate dehydrogenase-like domain
   1. G3DSA:3.40.71...
      33 - 367
      GENE3D
      G3DSA:3.40.718.10 (G3DSA:3.40.718.10)
   2. PF00180 (Iso_dh)
      39 - 363
      Pfam
      PF00180 (Iso_dh)
4. IPR019818
   Isocitrate/isopropylmalate dehydrogenase, conserved site
   1. PS00470 (IDH_IMDH)
      258 - 277
      PROSITE patterns
      PS00470 (IDH_IMDH)

no IPR
Unintegrated signatures

1. PTHR11835:SF26 (ISO...)
   33 - 368
   PANTHER
   PTHR11835:SF26 (ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL)
2. SSF53659 (Isocitrat...)
   31 - 367
   SUPERFAMILY
   SSF53659 (Isocitrate/Isopropylmalate dehydrogenase-like)

### GO term prediction

#### Biological Process

GO:0006099 tricarboxylic acid cycle
GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0000287 magnesium ion binding
GO:0004449 isocitrate dehydrogenase (NAD+) activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

#### Cellular Component

None predicted.