Protein

## EMLSAP00000003313

Length
426 amino acids

### Protein family membership

- Neurotransmitter-gated ion-channel (IPR006201)
  - Gamma-aminobutyric acid A receptor (IPR006028)

### Domains and repeats

1. Domain
   37 - 249
   - Neurotransmitter-gated ion-channel ligand-binding (IPR006202)
2. Domain
   249 - 421
   - Neurotransmitter-gated ion-channel transmembrane domain (IPR006029)

1 50 100 150 200 250 300 350 400 426

### Detailed signature matches

1. IPR006201
   Neurotransmitter-gated ion-channel
   1. PTHR18945 (NEUROTRA...)
      37 - 421
      PANTHER
      PTHR18945 (NEUROTRANSMITTER GATED ION CHANNEL)
   2. PR00252 (NRIONCHANNEL)
      119 - 130
      PRINTS
      PR00252 (NRIONCHANNEL)
      75 - 91
      PRINTS
      PR00252 (NRIONCHANNEL)
      165 - 179
      PRINTS
      PR00252 (NRIONCHANNEL)
      241 - 253
      PRINTS
      PR00252 (NRIONCHANNEL)
2. IPR006028
   Gamma-aminobutyric acid A receptor
   1. PR00253 (GABAARECEPTR)
      250 - 270
      PRINTS
      PR00253 (GABAARECEPTR)
      276 - 297
      PRINTS
      PR00253 (GABAARECEPTR)
      310 - 331
      PRINTS
      PR00253 (GABAARECEPTR)
      397 - 417
      PRINTS
      PR00253 (GABAARECEPTR)
3. IPR006202
   Neurotransmitter-gated ion-channel ligand-binding
   1. PF02931 (Neur_chan_LBD)
      38 - 202
      Pfam
      PF02931 (Neur_chan_LBD)
   2. SSF63712 (Nicotinic...)
      37 - 246
      SUPERFAMILY
      SSF63712 (Nicotinic receptor ligand binding domain-like)
   3. G3DSA:2.70.17...
      41 - 249
      GENE3D
      G3DSA:2.70.170.10 (G3DSA:2.70.170.10)
4. IPR006029
   Neurotransmitter-gated ion-channel transmembrane domain
   1. SSF90112 (Neurotran...)
      249 - 421
      SUPERFAMILY
      SSF90112 (Neurotransmitter-gated ion-channel transmembrane pore)
   2. PF02932 (Neur_chan_...)
      255 - 375
      Pfam
      PF02932 (Neur_chan_memb)
5. IPR018000
   Neurotransmitter-gated ion-channel, conserved site
   1. PS00236 (NEUROTR_IO...)
      165 - 179
      PROSITE patterns
      PS00236 (NEUROTR_ION_CHANNEL)

no IPR
Unintegrated signatures

1. G3DSA:1.20.58...
   250 - 339
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
   390 - 418
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
2. PTHR18945:SF201 (GA...)
   37 - 421
   PANTHER
   PTHR18945:SF201 (GAMMA-AMINOBUTYRIC ACID A RECEPTOR BETA-RELATED)
3. SignalP-TM
   1 - 23
   SignalP Gram+ prok
   SignalP-TM (SignalP-TM)
4. SignalP-noTM
   1 - 22
   SignalP euk
   SignalP-noTM (SignalP-noTM)
5. TMhelix
   396 - 418
   TMHMM
   TMhelix (TMhelix)
   248 - 270
   TMHMM
   TMhelix (TMhelix)
   312 - 334
   TMHMM
   TMhelix (TMhelix)
   275 - 297
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006810 transport
GO:0006811 ion transport

#### Molecular Function

GO:0005230 extracellular ligand-gated ion channel activity

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane