Protein

## EMLSAP00000009932

Length
1,032 amino acids

### Protein family membership

- Peptidyl-glycine alpha-amidating monooxygenase (IPR000720)

### Domains and repeats

1. Domain
   20 - 162
   - Copper type II, ascorbate-dependent monooxygenase, N-terminal (IPR000323)
   166 - 243
   - Copper type II, ascorbate-dependent monooxygenase-like, C-terminal (IPR014784)
   305 - 452
   - Copper type II, ascorbate-dependent monooxygenase, N-terminal (IPR000323)
   456 - 553
   - Copper type II, ascorbate-dependent monooxygenase-like, C-terminal (IPR014784)
2. Domain
   23 - 158
   - PHM/PNGase F domain (IPR008977)
   161 - 244
   - PHM/PNGase F domain (IPR008977)
   305 - 447
   - PHM/PNGase F domain (IPR008977)
   451 - 554
   - PHM/PNGase F domain (IPR008977)
   605 - 817
   - Six-bladed beta-propeller, TolB-like (IPR011042)
   861 - 903
   - Six-bladed beta-propeller, TolB-like (IPR011042)
3. Repeat
   675 - 698
   - NHL repeat, subgroup (IPR013017)
   700 - 740
   - NHL repeat, subgroup (IPR013017)
   774 - 805
   - NHL repeat, subgroup (IPR013017)
   864 - 886
   - NHL repeat, subgroup (IPR013017)
4. Repeat
   708 - 737
   - NHL repeat (IPR001258)
   774 - 802
   - NHL repeat (IPR001258)

1 100 200 300 400 500 600 700 800 900 1032

### Detailed signature matches

1. IPR000720
   Peptidyl-glycine alpha-amidating monooxygenase
   1. PR00790 (PAMONOXGNASE)
      63 - 84
      PRINTS
      PR00790 (PAMONOXGNASE)
      225 - 244
      PRINTS
      PR00790 (PAMONOXGNASE)
      104 - 123
      PRINTS
      PR00790 (PAMONOXGNASE)
2. IPR000323
   Copper type II, ascorbate-dependent monooxygenase, N-terminal
   1. PF01082 (Cu2_monoox...)
      23 - 141
      Pfam
      PF01082 (Cu2_monooxygen)
      311 - 435
      Pfam
      PF01082 (Cu2_monooxygen)
   2. G3DSA:2.60.12...
      20 - 162
      GENE3D
      G3DSA:2.60.120.310 (G3DSA:2.60.120.310)
      305 - 452
      GENE3D
      G3DSA:2.60.120.310 (G3DSA:2.60.120.310)
3. IPR008977
   PHM/PNGase F domain
   1. SSF49742 (PHM/PNGase F)
      451 - 554
      SUPERFAMILY
      SSF49742 (PHM/PNGase F)
      305 - 447
      SUPERFAMILY
      SSF49742 (PHM/PNGase F)
      161 - 244
      SUPERFAMILY
      SSF49742 (PHM/PNGase F)
      23 - 158
      SUPERFAMILY
      SSF49742 (PHM/PNGase F)
4. IPR014784
   Copper type II, ascorbate-dependent monooxygenase-like, C-terminal
   1. G3DSA:2.60.12...
      166 - 243
      GENE3D
      G3DSA:2.60.120.230 (G3DSA:2.60.120.230)
      456 - 553
      GENE3D
      G3DSA:2.60.120.230 (G3DSA:2.60.120.230)
5. IPR011042
   Six-bladed beta-propeller, TolB-like
   1. G3DSA:2.120.1...
      861 - 903
      GENE3D
      G3DSA:2.120.10.30 (G3DSA:2.120.10.30)
      605 - 817
      GENE3D
      G3DSA:2.120.10.30 (G3DSA:2.120.10.30)
6. IPR013017
   NHL repeat, subgroup
   1. PS51125 (NHL)
      675 - 698
      PROSITE profiles
      PS51125 (NHL)
      774 - 805
      PROSITE profiles
      PS51125 (NHL)
      700 - 740
      PROSITE profiles
      PS51125 (NHL)
      864 - 886
      PROSITE profiles
      PS51125 (NHL)
7. IPR001258
   NHL repeat
   1. PF01436 (NHL)
      708 - 737
      Pfam
      PF01436 (NHL)
      774 - 802
      Pfam
      PF01436 (NHL)

no IPR
Unintegrated signatures

1. PF03712 (Cu2_monoox_C)
   452 - 553
   Pfam
   PF03712 (Cu2_monoox_C)
   165 - 245
   Pfam
   PF03712 (Cu2_monoox_C)
2. PTHR10680 (PEPTIDYL...)
   1 - 1,024
   PANTHER
   PTHR10680 (PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE)
3. SSF101898 (NHL repeat)
   606 - 899
   SUPERFAMILY
   SSF101898 (NHL repeat)
4. SignalP-noTM
   1 - 21
   SignalP euk
   SignalP-noTM (SignalP-noTM)

### GO term prediction

#### Biological Process

GO:0006518 peptide metabolic process
GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0003824 catalytic activity
GO:0004497 monooxygenase activity
GO:0004504 peptidylglycine monooxygenase activity
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen

#### Cellular Component

GO:0016020 membrane