Protein

## EMLSAP00000002856

Length
409 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   1 - 109
   - Immunoglobulin E-set (IPR014756)
   165 - 195
   - Alpha-2-macroglobulin, thiol-ester bond-forming (IPR019565)
2. Domain
   1 - 34
   - Alpha-2-macroglobulin (IPR001599)
   163 - 401
   - Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (IPR008930)
     - Alpha-macroglobulin complement component (IPR011626)

1 50 100 150 200 250 300 350 409

### Detailed signature matches

1. IPR001599
   Alpha-2-macroglobulin
   1. PF00207 (A2M)
      1 - 34
      Pfam
      PF00207 (A2M)
2. IPR014756
   Immunoglobulin E-set
   1. SSF81296 (E set dom...)
      1 - 109
      SUPERFAMILY
      SSF81296 (E set domains)
3. IPR008930
   Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
   1. SSF48239 (Terpenoid...)
      163 - 398
      SUPERFAMILY
      SSF48239 (Terpenoid cyclases/Protein prenyltransferases)
4. IPR019565
   Alpha-2-macroglobulin, thiol-ester bond-forming
   1. PF10569 (Thiol-este...)
      165 - 195
      Pfam
      PF10569 (Thiol-ester_cl)
5. IPR011626
   Alpha-macroglobulin complement component
   1. PF07678 (A2M_comp)
      215 - 401
      Pfam
      PF07678 (A2M_comp)
6. IPR019742
   Alpha-2-macroglobulin, conserved site
   1. PS00477 (ALPHA_2_MA...)
      173 - 181
      PROSITE patterns
      PS00477 (ALPHA_2_MACROGLOBULIN)

no IPR
Unintegrated signatures

1. G3DSA:1.50.10.20
   163 - 402
   GENE3D
   G3DSA:1.50.10.20 (G3DSA:1.50.10.20)
2. PTHR11412 (MACROGLO...)
   1 - 336
   PANTHER
   PTHR11412 (MACROGLOBULIN/COMPLEMENT)
3. PTHR11412:SF36 (ALP...)
   1 - 336
   PANTHER
   PTHR11412:SF36 (ALPHA-MACROGLOBULIN)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0004866 endopeptidase inhibitor activity

#### Cellular Component

GO:0005615 extracellular space