Protein

## EMLSAP00000009281

Length
535 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   24 - 76
   - Kazal domain (IPR002350)
   158 - 254
   - EF-hand domain pair (IPR011992)
     - SPARC/Testican, calcium-binding domain (IPR019577)
   402 - 511
   - EF-hand domain pair (IPR011992)
     - SPARC/Testican, calcium-binding domain (IPR019577)
2. Domain
   74 - 144
   - Thyroglobulin type-1 (IPR000716)
   185 - 220
   - EF-hand domain (IPR002048)
   222 - 257
   - EF-hand domain (IPR002048)
   313 - 381
   - Thyroglobulin type-1 (IPR000716)
   437 - 472
   - EF-hand domain (IPR002048)

1 50 100 150 200 250 300 350 400 450 500 535

### Detailed signature matches

1. IPR002350
   Kazal domain
   1. SM00280 (KAZAL)
      29 - 74
      SMART
      SM00280 (KAZAL)
   2. PS51465 (KAZAL_2)
      24 - 76
      PROSITE profiles
      PS51465 (KAZAL_2)
   3. PF07648 (Kazal_2)
      34 - 74
      Pfam
      PF07648 (Kazal_2)
2. IPR000716
   Thyroglobulin type-1
   1. PS00484 (THYROGLOBU...)
      100 - 129
      PROSITE patterns
      PS00484 (THYROGLOBULIN_1_1)
      332 - 362
      PROSITE patterns
      PS00484 (THYROGLOBULIN_1_1)
   2. PS51162 (THYROGLOBU...)
      78 - 144
      PROSITE profiles
      PS51162 (THYROGLOBULIN_1_2)
      313 - 377
      PROSITE profiles
      PS51162 (THYROGLOBULIN_1_2)
   3. PF00086 (Thyroglobu...)
      89 - 139
      Pfam
      PF00086 (Thyroglobulin_1)
      325 - 377
      Pfam
      PF00086 (Thyroglobulin_1)
   4. SSF57610 (Thyroglob...)
      325 - 378
      SUPERFAMILY
      SSF57610 (Thyroglobulin type-1 domain)
      74 - 142
      SUPERFAMILY
      SSF57610 (Thyroglobulin type-1 domain)
   5. G3DSA:4.10.80...
      91 - 142
      GENE3D
      G3DSA:4.10.800.10 (G3DSA:4.10.800.10)
      325 - 378
      GENE3D
      G3DSA:4.10.800.10 (G3DSA:4.10.800.10)
   6. SM00211 (TY)
      333 - 381
      SMART
      SM00211 (TY)
      101 - 140
      SMART
      SM00211 (TY)
3. IPR011992
   EF-hand domain pair
   1. G3DSA:1.10.23...
      402 - 511
      GENE3D
      G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
      158 - 254
      GENE3D
      G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
4. IPR019577
   SPARC/Testican, calcium-binding domain
   1. PF10591 (SPARC_Ca_bdg)
      402 - 502
      Pfam
      PF10591 (SPARC_Ca_bdg)
      171 - 250
      Pfam
      PF10591 (SPARC_Ca_bdg)
5. IPR002048
   EF-hand domain
   1. SM00054 (EFh)
      189 - 217
      SMART
      SM00054 (EFh)
      441 - 469
      SMART
      SM00054 (EFh)
   2. PS50222 (EF_HAND_2)
      437 - 472
      PROSITE profiles
      PS50222 (EF_HAND_2)
      222 - 257
      PROSITE profiles
      PS50222 (EF_HAND_2)
      185 - 220
      PROSITE profiles
      PS50222 (EF_HAND_2)
6. IPR018247
   EF-Hand 1, calcium-binding site
   1. PS00018 (EF_HAND_1)
      487 - 499
      PROSITE patterns
      PS00018 (EF_HAND_1)
      235 - 247
      PROSITE patterns
      PS00018 (EF_HAND_1)
      450 - 462
      PROSITE patterns
      PS00018 (EF_HAND_1)

no IPR
Unintegrated signatures

1. G3DSA:3.30.60.30
   40 - 74
   GENE3D
   G3DSA:3.30.60.30 (G3DSA:3.30.60.30)
2. PTHR12352 (SECRETED...)
   30 - 532
   PANTHER
   PTHR12352 (SECRETED MODULAR CALCIUM-BINDING PROTEIN)
3. PTHR12352:SF3 (SUBF...)
   30 - 532
   PANTHER
   PTHR12352:SF3 (SUBFAMILY NOT NAMED)
4. SSF100895 (Kazal-ty...)
   12 - 74
   SUPERFAMILY
   SSF100895 (Kazal-type serine protease inhibitors)
5. SSF47473 (EF-hand)
   185 - 254
   SUPERFAMILY
   SSF47473 (EF-hand)
   402 - 511
   SUPERFAMILY
   SSF47473 (EF-hand)
6. SignalP-noTM
   1 - 18
   SignalP euk
   SignalP-noTM (SignalP-noTM)

### GO term prediction

#### Biological Process

GO:0007165 signal transduction

#### Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

#### Cellular Component

GO:0005578 proteinaceous extracellular matrix