Protein

## EMLSAP00000008592

Length
1,575 amino acids

### Protein family membership

- Histidine phosphatase superfamily, clade-2 (IPR000560)

### Domains and repeats

1. Domain
   27 - 53
   - Glyoxalase/fosfomycin resistance/dioxygenase domain (IPR004360)
   547 - 972
   - Ankyrin repeat-containing domain (IPR020683)
   1,019 - 1,068
   - Ankyrin repeat-containing domain (IPR020683)
2. Repeat
   569 - 600
   - Ankyrin repeat (IPR002110)
   606 - 638
   - Ankyrin repeat (IPR002110)
   639 - 667
   - Ankyrin repeat (IPR002110)
   801 - 830
   - Ankyrin repeat (IPR002110)
   835 - 874
   - Ankyrin repeat (IPR002110)
   875 - 905
   - Ankyrin repeat (IPR002110)
   912 - 942
   - Ankyrin repeat (IPR002110)
   958 - 989
   - Ankyrin repeat (IPR002110)
   1,046 - 1,075
   - Ankyrin repeat (IPR002110)

1 200 400 600 800 1000 1200 1400 1575

### Detailed signature matches

1. IPR000560
   Histidine phosphatase superfamily, clade-2
   1. PF00328 (His_Phos_2)
      143 - 407
      Pfam
      PF00328 (His_Phos_2)
2. IPR004360
   Glyoxalase/fosfomycin resistance/dioxygenase domain
   1. PF00903 (Glyoxalase)
      27 - 53
      Pfam
      PF00903 (Glyoxalase)
3. IPR020683
   Ankyrin repeat-containing domain
   1. PS50297 (ANK_REP_RE...)
      569 - 944
      PROSITE profiles
      PS50297 (ANK_REP_REGION)
   2. G3DSA:1.25.40.20
      568 - 684
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
      1,028 - 1,068
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
      771 - 972
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
   3. SSF48403 (Ankyrin r...)
      571 - 667
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
      770 - 952
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
      1,019 - 1,061
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
   4. PF12796 (Ank_2)
      771 - 852
      Pfam
      PF12796 (Ank_2)
      547 - 634
      Pfam
      PF12796 (Ank_2)
4. IPR002110
   Ankyrin repeat
   1. SM00248 (ANK)
      958 - 989
      SMART
      SM00248 (ANK)
      801 - 830
      SMART
      SM00248 (ANK)
      569 - 600
      SMART
      SM00248 (ANK)
      606 - 635
      SMART
      SM00248 (ANK)
      1,046 - 1,075
      SMART
      SM00248 (ANK)
      912 - 942
      SMART
      SM00248 (ANK)
      875 - 905
      SMART
      SM00248 (ANK)
      639 - 667
      SMART
      SM00248 (ANK)
      835 - 871
      SMART
      SM00248 (ANK)
   2. PS50088 (ANK_REPEAT)
      606 - 638
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      835 - 874
      PROSITE profiles
      PS50088 (ANK_REPEAT)

no IPR
Unintegrated signatures

1. G3DSA:3.10.18...
   27 - 55
   GENE3D
   G3DSA:3.10.180.10 (G3DSA:3.10.180.10)
2. G3DSA:3.40.50...
   141 - 480
   GENE3D
   G3DSA:3.40.50.1240 (G3DSA:3.40.50.1240)
3. PTHR20963 (MULTIPLE...)
   29 - 486
   PANTHER
   PTHR20963 (MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED)
4. SSF53254 (Phosphogl...)
   109 - 480
   SUPERFAMILY
   SSF53254 (Phosphoglycerate mutase-like)
5. SSF54593 (Glyoxalas...)
   20 - 55
   SUPERFAMILY
   SSF54593 (Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase)
6. TMhelix
   1,497 - 1,519
   TMHMM
   TMhelix (TMhelix)
   1,362 - 1,384
   TMHMM
   TMhelix (TMhelix)
   74 - 91
   TMHMM
   TMhelix (TMhelix)
   1,418 - 1,440
   TMHMM
   TMhelix (TMhelix)
   1,330 - 1,352
   TMHMM
   TMhelix (TMhelix)
   1,115 - 1,137
   TMHMM
   TMhelix (TMhelix)
   1,221 - 1,243
   TMHMM
   TMhelix (TMhelix)
   1,389 - 1,408
   TMHMM
   TMhelix (TMhelix)
   1,179 - 1,201
   TMHMM
   TMhelix (TMhelix)
   1,461 - 1,482
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0003993 acid phosphatase activity
GO:0005515 protein binding

#### Cellular Component

None predicted.