Protein

## EMLSAP00000009315

Length
2,562 amino acids

### Protein family membership

- Dynein heavy chain (IPR026983)

### Domains and repeats

1. Domain
   27 - 55
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   57 - 85
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   86 - 114
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   115 - 143
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   144 - 172
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   173 - 200
   - Zinc finger, C2H2-like (IPR015880)
     - Zinc finger, C2H2 (IPR007087)
   248 - 371
   - Dynein heavy chain, domain-2 (IPR013602)
   381 - 549
   - Dynein heavy chain, domain-2 (IPR013602)
   1,165 - 1,270
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   1,752 - 2,079
   - Dynein heavy chain, coiled coil stalk (IPR024743)
2. Domain
   79 - 107
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)
   114 - 143
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)
   144 - 165
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)
   166 - 198
   - Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)

1 500 1000 1500 2000 2562

### Detailed signature matches

1. IPR026983
   Dynein heavy chain
   1. PTHR10676 (DYNEIN H...)
      1,156 - 2,388
      PANTHER
      PTHR10676 (DYNEIN HEAVY CHAIN FAMILY PROTEIN)
2. IPR015880
   Zinc finger, C2H2-like
   1. SM00355 (ZnF_C2H2)
      57 - 80
      SMART
      SM00355 (ZnF_C2H2)
      173 - 195
      SMART
      SM00355 (ZnF_C2H2)
      86 - 109
      SMART
      SM00355 (ZnF_C2H2)
      27 - 50
      SMART
      SM00355 (ZnF_C2H2)
      144 - 167
      SMART
      SM00355 (ZnF_C2H2)
      115 - 138
      SMART
      SM00355 (ZnF_C2H2)
3. IPR007087
   Zinc finger, C2H2
   1. PF00096 (zf-C2H2)
      144 - 167
      Pfam
      PF00096 (zf-C2H2)
      115 - 138
      Pfam
      PF00096 (zf-C2H2)
   2. PS50157 (ZINC_FINGE...)
      27 - 55
      PROSITE profiles
      PS50157 (ZINC_FINGER_C2H2_2)
      144 - 172
      PROSITE profiles
      PS50157 (ZINC_FINGER_C2H2_2)
      173 - 200
      PROSITE profiles
      PS50157 (ZINC_FINGER_C2H2_2)
      57 - 85
      PROSITE profiles
      PS50157 (ZINC_FINGER_C2H2_2)
      86 - 114
      PROSITE profiles
      PS50157 (ZINC_FINGER_C2H2_2)
      115 - 143
      PROSITE profiles
      PS50157 (ZINC_FINGER_C2H2_2)
   3. PS00028 (ZINC_FINGE...)
      29 - 50
      PROSITE patterns
      PS00028 (ZINC_FINGER_C2H2_1)
      59 - 81
      PROSITE patterns
      PS00028 (ZINC_FINGER_C2H2_1)
      88 - 109
      PROSITE patterns
      PS00028 (ZINC_FINGER_C2H2_1)
      117 - 138
      PROSITE patterns
      PS00028 (ZINC_FINGER_C2H2_1)
      146 - 167
      PROSITE patterns
      PS00028 (ZINC_FINGER_C2H2_1)
      175 - 195
      PROSITE patterns
      PS00028 (ZINC_FINGER_C2H2_1)
4. IPR013087
   Zinc finger C2H2-type/integrase DNA-binding domain
   1. G3DSA:3.30.16...
      114 - 143
      GENE3D
      G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
      79 - 107
      GENE3D
      G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
      144 - 165
      GENE3D
      G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
      166 - 198
      GENE3D
      G3DSA:3.30.160.60 (G3DSA:3.30.160.60)
5. IPR013602
   Dynein heavy chain, domain-2
   1. PF08393 (DHC_N2)
      248 - 371
      Pfam
      PF08393 (DHC_N2)
      381 - 549
      Pfam
      PF08393 (DHC_N2)
6. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      1,165 - 1,270
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
7. IPR024743
   Dynein heavy chain, coiled coil stalk
   1. PF12777 (MT)
      1,752 - 2,079
      Pfam
      PF12777 (MT)

no IPR
Unintegrated signatures

1. Coil
   294 - 322
   COILS
   Coil (Coil)
   1,787 - 1,808
   COILS
   Coil (Coil)
2. G3DSA:3.40.50...
   1,632 - 1,687
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   1,154 - 1,281
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PF13894 (zf-C2H2_4)
   27 - 50
   Pfam
   PF13894 (zf-C2H2_4)
   86 - 109
   Pfam
   PF13894 (zf-C2H2_4)
   58 - 80
   Pfam
   PF13894 (zf-C2H2_4)
4. PTHR10676:SF136 (DY...)
   1,156 - 2,388
   PANTHER
   PTHR10676:SF136 (DYNEIN HEAVY CHAIN 6, AXONEMAL-RELATED)
5. SSF57667 (beta-beta...)
   57 - 106
   SUPERFAMILY
   SSF57667 (beta-beta-alpha zinc fingers)
   95 - 153
   SUPERFAMILY
   SSF57667 (beta-beta-alpha zinc fingers)
   143 - 195
   SUPERFAMILY
   SSF57667 (beta-beta-alpha zinc fingers)

### GO term prediction

#### Biological Process

GO:0007018 microtubule-based movement

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0003777 microtubule motor activity
GO:0046872 metal ion binding

#### Cellular Component

None predicted.