Protein

## EMLSAP00000009714

Length
1,591 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   156 - 263
   - Voltage-dependent channel, four helix bundle domain (IPR027359)
   623 - 735
   - Voltage-dependent channel, four helix bundle domain (IPR027359)
   1,008 - 1,118
   - Voltage-dependent channel, four helix bundle domain (IPR027359)
   1,330 - 1,415
   - Voltage-dependent channel, four helix bundle domain (IPR027359)
2. Domain
   196 - 444
   - Ion transport domain (IPR005821)
   668 - 852
   - Ion transport domain (IPR005821)
   959 - 1,021
   - Sodium ion transport-associated (IPR010526)
   1,047 - 1,271
   - Ion transport domain (IPR005821)
   1,366 - 1,456
   - Ion transport domain (IPR005821)

1 200 400 600 800 1000 1200 1400 1591

### Detailed signature matches

1. IPR027359
   Voltage-dependent channel, four helix bundle domain
   1. G3DSA:1.20.12...
      623 - 735
      GENE3D
      G3DSA:1.20.120.350 (G3DSA:1.20.120.350)
      1,008 - 1,118
      GENE3D
      G3DSA:1.20.120.350 (G3DSA:1.20.120.350)
      156 - 263
      GENE3D
      G3DSA:1.20.120.350 (G3DSA:1.20.120.350)
      1,330 - 1,415
      GENE3D
      G3DSA:1.20.120.350 (G3DSA:1.20.120.350)
2. IPR005821
   Ion transport domain
   1. PF00520 (Ion_trans)
      1,047 - 1,271
      Pfam
      PF00520 (Ion_trans)
      1,366 - 1,456
      Pfam
      PF00520 (Ion_trans)
      196 - 444
      Pfam
      PF00520 (Ion_trans)
      668 - 852
      Pfam
      PF00520 (Ion_trans)
3. IPR010526
   Sodium ion transport-associated
   1. PF06512 (Na_trans_a...)
      959 - 1,021
      Pfam
      PF06512 (Na_trans_assoc)

no IPR
Unintegrated signatures

1. Coil
   441 - 476
   COILS
   Coil (Coil)
2. G3DSA:1.20.5.150
   1,273 - 1,303
   GENE3D
   G3DSA:1.20.5.150 (G3DSA:1.20.5.150)
3. PTHR10037 (VOLTAGE-...)
   89 - 1,465
   PANTHER
   PTHR10037 (VOLTAGE-GATED CATION CHANNEL (CALCIUM AND SODIUM))
4. PTHR10037:SF23 (SOD...)
   89 - 1,465
   PANTHER
   PTHR10037:SF23 (SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA)
5. SSF81324 (Voltage-g...)
   1,332 - 1,455
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   383 - 448
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   166 - 310
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   624 - 858
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   1,200 - 1,278
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
   1,012 - 1,165
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
6. TMhelix
   229 - 251
   TMHMM
   TMhelix (TMhelix)
   832 - 854
   TMHMM
   TMhelix (TMhelix)
   422 - 444
   TMHMM
   TMhelix (TMhelix)
   285 - 307
   TMHMM
   TMhelix (TMhelix)
   1,083 - 1,105
   TMHMM
   TMhelix (TMhelix)
   167 - 186
   TMHMM
   TMhelix (TMhelix)
   1,368 - 1,385
   TMHMM
   TMhelix (TMhelix)
   1,394 - 1,411
   TMHMM
   TMhelix (TMhelix)
   618 - 640
   TMHMM
   TMhelix (TMhelix)
   751 - 773
   TMHMM
   TMhelix (TMhelix)
   1,336 - 1,353
   TMHMM
   TMhelix (TMhelix)
   1,012 - 1,030
   TMHMM
   TMhelix (TMhelix)
   1,128 - 1,159
   TMHMM
   TMhelix (TMhelix)
   666 - 688
   TMHMM
   TMhelix (TMhelix)
   703 - 725
   TMHMM
   TMhelix (TMhelix)
   258 - 280
   TMHMM
   TMhelix (TMhelix)
   1,051 - 1,073
   TMHMM
   TMhelix (TMhelix)
   1,250 - 1,272
   TMHMM
   TMhelix (TMhelix)
   805 - 827
   TMHMM
   TMhelix (TMhelix)
   1,426 - 1,448
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006811 ion transport
GO:0006814 sodium ion transport
GO:0055085 transmembrane transport

#### Molecular Function

GO:0005216 ion channel activity
GO:0005248 voltage-gated sodium channel activity

#### Cellular Component

GO:0001518 voltage-gated sodium channel complex
GO:0016020 membrane