Protein

## EMLSAP00000003120

Length
945 amino acids

### Protein family membership

- Neurotransmitter-gated ion-channel (IPR006201)
  - Gamma-aminobutyric acid A receptor (IPR006028)

### Domains and repeats

1. Domain
   226 - 325
   - ELM2 domain (IPR000949)
   488 - 700
   - Neurotransmitter-gated ion-channel ligand-binding (IPR006202)
2. Domain
   318 - 382
   - Homeodomain-like (IPR009057)
     - SANT/Myb domain (IPR001005)
       - SANT domain (IPR017884)
   699 - 943
   - Neurotransmitter-gated ion-channel transmembrane domain (IPR006029)

1 100 200 300 400 500 600 700 800 945

### Detailed signature matches

1. IPR006201
   Neurotransmitter-gated ion-channel
   1. PR00252 (NRIONCHANNEL)
      692 - 704
      PRINTS
      PR00252 (NRIONCHANNEL)
      564 - 575
      PRINTS
      PR00252 (NRIONCHANNEL)
      610 - 624
      PRINTS
      PR00252 (NRIONCHANNEL)
      530 - 546
      PRINTS
      PR00252 (NRIONCHANNEL)
2. IPR006028
   Gamma-aminobutyric acid A receptor
   1. PR00253 (GABAARECEPTR)
      727 - 748
      PRINTS
      PR00253 (GABAARECEPTR)
      701 - 721
      PRINTS
      PR00253 (GABAARECEPTR)
      760 - 781
      PRINTS
      PR00253 (GABAARECEPTR)
      921 - 941
      PRINTS
      PR00253 (GABAARECEPTR)
3. IPR000949
   ELM2 domain
   1. PF01448 (ELM2)
      228 - 274
      Pfam
      PF01448 (ELM2)
   2. PS51156 (ELM2)
      226 - 325
      PROSITE profiles
      PS51156 (ELM2)
4. IPR009057
   Homeodomain-like
   1. SSF46689 (Homeodoma...)
      318 - 382
      SUPERFAMILY
      SSF46689 (Homeodomain-like)
5. IPR001005
   SANT/Myb domain
   1. SM00717 (SANT)
      331 - 380
      SMART
      SM00717 (SANT)
6. IPR017884
   SANT domain
   1. PS51293 (SANT)
      330 - 382
      PROSITE profiles
      PS51293 (SANT)
7. IPR006202
   Neurotransmitter-gated ion-channel ligand-binding
   1. PF02931 (Neur_chan_LBD)
      488 - 697
      Pfam
      PF02931 (Neur_chan_LBD)
   2. SSF63712 (Nicotinic...)
      488 - 675
      SUPERFAMILY
      SSF63712 (Nicotinic receptor ligand binding domain-like)
   3. G3DSA:2.70.17...
      494 - 700
      GENE3D
      G3DSA:2.70.170.10 (G3DSA:2.70.170.10)
8. IPR006029
   Neurotransmitter-gated ion-channel transmembrane domain
   1. SSF90112 (Neurotran...)
      699 - 943
      SUPERFAMILY
      SSF90112 (Neurotransmitter-gated ion-channel transmembrane pore)
   2. PF02932 (Neur_chan_...)
      705 - 935
      Pfam
      PF02932 (Neur_chan_memb)
9. IPR018000
   Neurotransmitter-gated ion-channel, conserved site
   1. PS00236 (NEUROTR_IO...)
      610 - 624
      PROSITE patterns
      PS00236 (NEUROTR_ION_CHANNEL)

no IPR
Unintegrated signatures

1. Coil
   43 - 67
   COILS
   Coil (Coil)
2. G3DSA:1.20.58...
   918 - 942
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
   701 - 793
   GENE3D
   G3DSA:1.20.58.390 (G3DSA:1.20.58.390)
3. PTHR10865 (METASTAS...)
   1 - 772
   PANTHER
   PTHR10865 (METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN)
4. PTHR10865:SF14 (MES...)
   1 - 772
   PANTHER
   PTHR10865:SF14 (MESODERM INDUCTION EARLY RESPONSE PROTEIN)
5. TMhelix
   762 - 784
   TMHMM
   TMhelix (TMhelix)
   925 - 944
   TMHMM
   TMhelix (TMhelix)
   730 - 747
   TMHMM
   TMhelix (TMhelix)
   701 - 723
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006810 transport
GO:0006811 ion transport

#### Molecular Function

GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005230 extracellular ligand-gated ion channel activity

#### Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane