Protein

## EMLSAP00000012082

Length
1,761 amino acids

### Protein family membership

- Isocitrate dehydrogenase NADP-dependent (IPR004790)

### Domains and repeats

1. Domain
   5 - 58
   - C-type lectin fold (IPR016187)
   86 - 212
   - Concanavalin A-like lectin/glucanases superfamily (IPR008985)
   398 - 798
   - Isopropylmalate dehydrogenase-like domain (IPR024084)
2. Domain
   79 - 209
   - Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
     - Laminin G domain (IPR001791)
   874 - 933
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   943 - 999
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,002 - 1,058
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,068 - 1,120
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,168 - 1,221
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,295 - 1,348
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,372 - 1,477
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,479 - 1,542
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,543 - 1,598
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,600 - 1,665
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)
   1,706 - 1,758
   - Kringle-like fold (IPR013806)
     - Fibronectin, type II, collagen-binding (IPR000562)

1 200 400 600 800 1000 1200 1400 1600 1761

### Detailed signature matches

1. IPR004790
   Isocitrate dehydrogenase NADP-dependent
   1. PTHR11822 (NADP-SPE...)
      343 - 804
      PANTHER
      PTHR11822 (NADP-SPECIFIC ISOCITRATE DEHYDROGENASE)
   2. TIGR00127
      397 - 799
      UNKNOWN
      TIGR00127 (TIGR00127)
2. IPR016187
   C-type lectin fold
   1. SSF56436 (C-type le...)
      5 - 58
      SUPERFAMILY
      SSF56436 (C-type lectin-like)
3. IPR013320
   Concanavalin A-like lectin/glucanase, subgroup
   1. G3DSA:2.60.12...
      79 - 207
      GENE3D
      G3DSA:2.60.120.200 (G3DSA:2.60.120.200)
4. IPR008985
   Concanavalin A-like lectin/glucanases superfamily
   1. SSF49899 (Concanava...)
      86 - 212
      SUPERFAMILY
      SSF49899 (Concanavalin A-like lectins/glucanases)
5. IPR001791
   Laminin G domain
   1. PF02210 (Laminin_G_2)
      117 - 209
      Pfam
      PF02210 (Laminin_G_2)
6. IPR024084
   Isopropylmalate dehydrogenase-like domain
   1. G3DSA:3.40.71...
      398 - 798
      GENE3D
      G3DSA:3.40.718.10 (G3DSA:3.40.718.10)
   2. PF00180 (Iso_dh)
      401 - 768
      Pfam
      PF00180 (Iso_dh)
7. IPR013806
   Kringle-like fold
   1. SSF57440 (Kringle-like)
      1,488 - 1,539
      SUPERFAMILY
      SSF57440 (Kringle-like)
      943 - 985
      SUPERFAMILY
      SSF57440 (Kringle-like)
      878 - 931
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,168 - 1,207
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,609 - 1,660
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,543 - 1,589
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,419 - 1,475
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,068 - 1,110
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,002 - 1,055
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,295 - 1,333
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,374 - 1,418
      SUPERFAMILY
      SSF57440 (Kringle-like)
      1,706 - 1,756
      SUPERFAMILY
      SSF57440 (Kringle-like)
8. IPR000562
   Fibronectin, type II, collagen-binding
   1. G3DSA:2.10.10.10
      1,074 - 1,109
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,175 - 1,206
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,553 - 1,588
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,302 - 1,332
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,706 - 1,756
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      948 - 984
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,426 - 1,475
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,600 - 1,665
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      874 - 932
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,479 - 1,542
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,003 - 1,058
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
      1,372 - 1,422
      GENE3D
      G3DSA:2.10.10.10 (G3DSA:2.10.10.10)
   2. PF00040 (fn2)
      1,305 - 1,333
      Pfam
      PF00040 (fn2)
      1,077 - 1,109
      Pfam
      PF00040 (fn2)
      1,498 - 1,539
      Pfam
      PF00040 (fn2)
      1,434 - 1,475
      Pfam
      PF00040 (fn2)
      1,178 - 1,208
      Pfam
      PF00040 (fn2)
      1,013 - 1,054
      Pfam
      PF00040 (fn2)
      956 - 984
      Pfam
      PF00040 (fn2)
      1,555 - 1,596
      Pfam
      PF00040 (fn2)
      890 - 931
      Pfam
      PF00040 (fn2)
      1,384 - 1,418
      Pfam
      PF00040 (fn2)
      1,715 - 1,756
      Pfam
      PF00040 (fn2)
      1,619 - 1,660
      Pfam
      PF00040 (fn2)
   3. SM00059 (FN2)
      883 - 931
      SMART
      SM00059 (FN2)
      1,298 - 1,346
      SMART
      SM00059 (FN2)
      1,006 - 1,054
      SMART
      SM00059 (FN2)
      1,491 - 1,539
      SMART
      SM00059 (FN2)
      1,427 - 1,475
      SMART
      SM00059 (FN2)
      1,708 - 1,756
      SMART
      SM00059 (FN2)
      1,548 - 1,596
      SMART
      SM00059 (FN2)
      1,171 - 1,219
      SMART
      SM00059 (FN2)
      1,377 - 1,426
      SMART
      SM00059 (FN2)
      1,612 - 1,660
      SMART
      SM00059 (FN2)
      1,070 - 1,118
      SMART
      SM00059 (FN2)
      949 - 997
      SMART
      SM00059 (FN2)
   4. PS51092 (FN2_2)
      1,710 - 1,758
      PROSITE profiles
      PS51092 (FN2_2)
      1,072 - 1,120
      PROSITE profiles
      PS51092 (FN2_2)
      1,173 - 1,221
      PROSITE profiles
      PS51092 (FN2_2)
      885 - 933
      PROSITE profiles
      PS51092 (FN2_2)
      1,550 - 1,598
      PROSITE profiles
      PS51092 (FN2_2)
      951 - 999
      PROSITE profiles
      PS51092 (FN2_2)
      1,493 - 1,541
      PROSITE profiles
      PS51092 (FN2_2)
      1,300 - 1,348
      PROSITE profiles
      PS51092 (FN2_2)
      1,614 - 1,662
      PROSITE profiles
      PS51092 (FN2_2)
      1,008 - 1,056
      PROSITE profiles
      PS51092 (FN2_2)
      1,379 - 1,428
      PROSITE profiles
      PS51092 (FN2_2)
      1,429 - 1,477
      PROSITE profiles
      PS51092 (FN2_2)

no IPR
Unintegrated signatures

1. SSF53659 (Isocitrat...)
   398 - 800
   SUPERFAMILY
   SSF53659 (Isocitrate/Isopropylmalate dehydrogenase-like)

### GO term prediction

#### Biological Process

GO:0006102 isocitrate metabolic process
GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0004450 isocitrate dehydrogenase (NADP+) activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

#### Cellular Component

None predicted.