Protein

## EMLSAP00000003883

Length
1,608 amino acids

### Protein family membership

- Afadin (IPR028842)

### Domains and repeats

1. Domain
   45 - 143
   - Ras-association (IPR000159)
   237 - 339
   - Ras-association (IPR000159)
   368 - 473
   - SMAD/FHA domain (IPR008984)
     - Forkhead-associated (FHA) domain (IPR000253)
   728 - 833
   - Dil domain (IPR018444)
2. Domain
   613 - 851
   - Dilute (IPR002710)
   955 - 1,054
   - PDZ domain (IPR001478)

1 200 400 600 800 1000 1200 1400 1608

### Detailed signature matches

1. IPR028842
   Afadin
   1. PTHR10398:SF0 (AFADIN)
      10 - 1,419
      PANTHER
      PTHR10398:SF0 (AFADIN)
2. IPR000159
   Ras-association
   1. PS50200 (RA)
      45 - 143
      PROSITE profiles
      PS50200 (RA)
      237 - 339
      PROSITE profiles
      PS50200 (RA)
   2. PF00788 (RA)
      46 - 142
      Pfam
      PF00788 (RA)
      239 - 338
      Pfam
      PF00788 (RA)
   3. SM00314 (RA)
      237 - 339
      SMART
      SM00314 (RA)
      45 - 143
      SMART
      SM00314 (RA)
3. IPR008984
   SMAD/FHA domain
   1. SSF49879 (SMAD/FHA ...)
      368 - 473
      SUPERFAMILY
      SSF49879 (SMAD/FHA domain)
4. IPR000253
   Forkhead-associated (FHA) domain
   1. G3DSA:2.60.20...
      371 - 471
      GENE3D
      G3DSA:2.60.200.20 (G3DSA:2.60.200.20)
   2. PF00498 (FHA)
      397 - 463
      Pfam
      PF00498 (FHA)
5. IPR002710
   Dilute
   1. PS51126 (DILUTE)
      613 - 851
      PROSITE profiles
      PS51126 (DILUTE)
6. IPR018444
   Dil domain
   1. PF01843 (DIL)
      728 - 833
      Pfam
      PF01843 (DIL)
7. IPR001478
   PDZ domain
   1. SSF50156 (PDZ domai...)
      955 - 1,054
      SUPERFAMILY
      SSF50156 (PDZ domain-like)
   2. PF00595 (PDZ)
      968 - 1,047
      Pfam
      PF00595 (PDZ)
   3. PS50106 (PDZ)
      966 - 1,051
      PROSITE profiles
      PS50106 (PDZ)
   4. SM00228 (PDZ)
      974 - 1,051
      SMART
      SM00228 (PDZ)

no IPR
Unintegrated signatures

1. Coil
   1,376 - 1,397
   COILS
   Coil (Coil)
   164 - 185
   COILS
   Coil (Coil)
2. G3DSA:2.30.42.10
   956 - 1,051
   GENE3D
   G3DSA:2.30.42.10 (G3DSA:2.30.42.10)
3. PTHR10398 (AFADIN)
   10 - 1,419
   PANTHER
   PTHR10398 (AFADIN)
4. SSF54236 (Ubiquitin...)
   238 - 337
   SUPERFAMILY
   SSF54236 (Ubiquitin-like)
   47 - 142
   SUPERFAMILY
   SSF54236 (Ubiquitin-like)

### GO term prediction

#### Biological Process

GO:0007165 signal transduction

#### Molecular Function

GO:0005515 protein binding

#### Cellular Component

GO:0005911 cell-cell junction