Protein

## EMLSAP00000012750

Length
976 amino acids

### Protein family membership

- NMDA receptor (IPR001508)

### Domains and repeats

1. Domain
   25 - 405
   - Periplasmic binding protein-like I (IPR028082)
   441 - 505
   - Glutamate receptor, L-glutamate/glycine-binding (IPR019594)
2. Domain
   45 - 391
   - Extracellular ligand-binding receptor (IPR001828)
   431 - 841
   - Ionotropic glutamate receptor (IPR001320)

1 100 200 300 400 500 600 700 800 900 976

### Detailed signature matches

1. IPR001508
   NMDA receptor
   1. PR00177 (NMDARECEPTOR)
      565 - 590
      PRINTS
      PR00177 (NMDARECEPTOR)
      830 - 854
      PRINTS
      PR00177 (NMDARECEPTOR)
      637 - 664
      PRINTS
      PR00177 (NMDARECEPTOR)
      475 - 503
      PRINTS
      PR00177 (NMDARECEPTOR)
2. IPR028082
   Periplasmic binding protein-like I
   1. SSF53822 (Periplasm...)
      25 - 405
      SUPERFAMILY
      SSF53822 (Periplasmic binding protein-like I)
3. IPR001828
   Extracellular ligand-binding receptor
   1. PF01094 (ANF_receptor)
      45 - 391
      Pfam
      PF01094 (ANF_receptor)
4. IPR001320
   Ionotropic glutamate receptor
   1. PF00060 (Lig_chan)
      563 - 841
      Pfam
      PF00060 (Lig_chan)
   2. SM00079 (PBPe)
      431 - 806
      SMART
      SM00079 (PBPe)
5. IPR019594
   Glutamate receptor, L-glutamate/glycine-binding
   1. PF10613 (Lig_chan-G...)
      441 - 504
      Pfam
      PF10613 (Lig_chan-Glu_bd)
   2. SM00918 (Lig_chan-G...)
      441 - 505
      SMART
      SM00918 (Lig_chan-Glu_bd)

no IPR
Unintegrated signatures

1. G3DSA:1.10.28...
   562 - 711
   GENE3D
   G3DSA:1.10.287.70 (G3DSA:1.10.287.70)
2. G3DSA:3.40.19...
   387 - 561
   GENE3D
   G3DSA:3.40.190.10 (G3DSA:3.40.190.10)
3. G3DSA:3.40.50...
   149 - 289
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
   25 - 145
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
   290 - 383
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
4. PTHR18966 (IONOTROP...)
   77 - 883
   PANTHER
   PTHR18966 (IONOTROPIC GLUTAMATE RECEPTOR)
5. PTHR18966:SF139 (SU...)
   77 - 883
   PANTHER
   PTHR18966:SF139 (SUBFAMILY NOT NAMED)
6. SSF53850 (Periplasm...)
   430 - 547
   SUPERFAMILY
   SSF53850 (Periplasmic binding protein-like II)
   666 - 807
   SUPERFAMILY
   SSF53850 (Periplasmic binding protein-like II)
7. SSF81324 (Voltage-g...)
   564 - 661
   SUPERFAMILY
   SSF81324 (Voltage-gated potassium channels)
8. SignalP-noTM
   1 - 23
   SignalP euk
   SignalP-noTM (SignalP-noTM)
9. TMhelix
   565 - 584
   TMHMM
   TMhelix (TMhelix)
   833 - 855
   TMHMM
   TMhelix (TMhelix)
   641 - 663
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006811 ion transport

#### Molecular Function

GO:0004872 receptor activity
GO:0004970 ionotropic glutamate receptor activity
GO:0005216 ion channel activity
GO:0005234 extracellular-glutamate-gated ion channel activity

#### Cellular Component

GO:0016020 membrane