Protein

## EMLSAP00000000667

Length
677 amino acids

### Protein family membership

- Arginine-tRNA ligase, class Ia (IPR001278)

### Domains and repeats

1. Domain
   92 - 199
   - Arginyl tRNA synthetase N-terminal domain (IPR005148)
   546 - 677
   - Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (IPR009080)
2. Domain
   192 - 543
   - Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
     - Arginyl-tRNA synthetase, class Ia, core (IPR015945)
   552 - 677
   - DALR anticodon binding (IPR008909)

1 100 200 300 400 500 600 677

### Detailed signature matches

1. IPR001278
   Arginine-tRNA ligase, class Ia
   1. PTHR11956 (ARGINYL-...)
      2 - 677
      PANTHER
      PTHR11956 (ARGINYL-TRNA SYNTHETASE)
   2. TIGR00456
      96 - 677
      UNKNOWN
      TIGR00456 (TIGR00456)
   3. MF_00123 (Arg_tRNA_...)
      91 - 677
      HAMAP
      MF_00123 (Arg_tRNA_synth)
2. IPR005148
   Arginyl tRNA synthetase N-terminal domain
   1. SSF55190 (Arginyl-t...)
      93 - 199
      SUPERFAMILY
      SSF55190 (Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain)
   2. SM01016 (Arg_tRNA_s...)
      95 - 183
      SMART
      SM01016 (Arg_tRNA_synt_N)
   3. PF03485 (Arg_tRNA_s...)
      96 - 183
      Pfam
      PF03485 (Arg_tRNA_synt_N)
   4. G3DSA:3.30.13...
      92 - 199
      GENE3D
      G3DSA:3.30.1360.70 (G3DSA:3.30.1360.70)
3. IPR014729
   Rossmann-like alpha/beta/alpha sandwich fold
   1. G3DSA:3.40.50...
      206 - 543
      GENE3D
      G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
4. IPR015945
   Arginyl-tRNA synthetase, class Ia, core
   1. PR01038 (TRNASYNTHARG)
      249 - 262
      PRINTS
      PR01038 (TRNASYNTHARG)
      210 - 225
      PRINTS
      PR01038 (TRNASYNTHARG)
      225 - 241
      PRINTS
      PR01038 (TRNASYNTHARG)
      392 - 413
      PRINTS
      PR01038 (TRNASYNTHARG)
   2. PF00750 (tRNA-synt_1d)
      192 - 538
      Pfam
      PF00750 (tRNA-synt_1d)
5. IPR009080
   Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
   1. SSF47323 (Anticodon...)
      546 - 677
      SUPERFAMILY
      SSF47323 (Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases)
6. IPR008909
   DALR anticodon binding
   1. SM00836 (DALR_1)
      552 - 677
      SMART
      SM00836 (DALR_1)
   2. PF05746 (DALR_1)
      552 - 677
      Pfam
      PF05746 (DALR_1)
7. IPR001412
   Aminoacyl-tRNA synthetase, class I, conserved site
   1. PS00178 (AA_TRNA_LI...)
      218 - 229
      PROSITE patterns
      PS00178 (AA_TRNA_LIGASE_I)

no IPR
Unintegrated signatures

1. Coil
   50 - 71
   COILS
   Coil (Coil)
   5 - 40
   COILS
   Coil (Coil)
2. G3DSA:1.10.73...
   546 - 677
   GENE3D
   G3DSA:1.10.730.10 (G3DSA:1.10.730.10)
3. PTHR11956:SF0 (SUBF...)
   2 - 677
   PANTHER
   PTHR11956:SF0 (SUBFAMILY NOT NAMED)
4. SSF52374 (Nucleotid...)
   206 - 545
   SUPERFAMILY
   SSF52374 (Nucleotidylyl transferase)

### GO term prediction

#### Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006420 arginyl-tRNA aminoacylation

#### Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004814 arginine-tRNA ligase activity
GO:0005524 ATP binding

#### Cellular Component

GO:0005737 cytoplasm