Protein

## EMLSAP00000004504

Length
1,150 amino acids

### Protein family membership

- NIPSNAP (IPR012577)

### Domains and repeats

1. Domain
   38 - 145
   - Dimeric alpha-beta barrel (IPR011008)
   150 - 224
   - Dimeric alpha-beta barrel (IPR011008)
   379 - 576
   - Alpha-2-macroglobulin RAP, C-terminal (IPR010483)
   729 - 792
   - CBS domain (IPR000644)
   809 - 867
   - CBS domain (IPR000644)
   882 - 944
   - CBS domain (IPR000644)
   953 - 1,014
   - CBS domain (IPR000644)
2. Domain
   272 - 361
   - Alpha-2-macroglobulin receptor-associated protein, domain 1 (IPR009066)
   375 - 464
   - Alpha-2-macroglobulin receptor-associated protein, domain 1 (IPR009066)
   473 - 571
   - Alpha-2-macroglobulin receptor-associated protein, domain 1 (IPR009066)

1 200 400 600 800 1000 1150

### Detailed signature matches

1. IPR012577
   NIPSNAP
   1. PF07978 (NIPSNAP)
      156 - 243
      Pfam
      PF07978 (NIPSNAP)
2. IPR011008
   Dimeric alpha-beta barrel
   1. SSF54909 (Dimeric a...)
      38 - 145
      SUPERFAMILY
      SSF54909 (Dimeric alpha+beta barrel)
      150 - 224
      SUPERFAMILY
      SSF54909 (Dimeric alpha+beta barrel)
3. IPR009066
   Alpha-2-macroglobulin receptor-associated protein, domain 1
   1. PF06400 (Alpha-2-MR...)
      272 - 359
      Pfam
      PF06400 (Alpha-2-MRAP_N)
   2. SSF47045 (RAP domai...)
      375 - 464
      SUPERFAMILY
      SSF47045 (RAP domain-like)
      282 - 359
      SUPERFAMILY
      SSF47045 (RAP domain-like)
      473 - 571
      SUPERFAMILY
      SSF47045 (RAP domain-like)
   3. G3DSA:1.20.81.10
      282 - 361
      GENE3D
      G3DSA:1.20.81.10 (G3DSA:1.20.81.10)
4. IPR010483
   Alpha-2-macroglobulin RAP, C-terminal
   1. PF06401 (Alpha-2-MR...)
      379 - 576
      Pfam
      PF06401 (Alpha-2-MRAP_C)
5. IPR000644
   CBS domain
   1. SM00116 (CBS)
      812 - 861
      SMART
      SM00116 (CBS)
      887 - 935
      SMART
      SM00116 (CBS)
      959 - 1,007
      SMART
      SM00116 (CBS)
      733 - 782
      SMART
      SM00116 (CBS)
   2. PS51371 (CBS)
      809 - 867
      PROSITE profiles
      PS51371 (CBS)
      729 - 792
      PROSITE profiles
      PS51371 (CBS)
      882 - 944
      PROSITE profiles
      PS51371 (CBS)
      953 - 1,014
      PROSITE profiles
      PS51371 (CBS)
   3. PF00571 (CBS)
      812 - 860
      Pfam
      PF00571 (CBS)
      887 - 931
      Pfam
      PF00571 (CBS)
      960 - 1,007
      Pfam
      PF00571 (CBS)

no IPR
Unintegrated signatures

1. Coil
   544 - 572
   COILS
   Coil (Coil)
   401 - 418
   COILS
   Coil (Coil)
   419 - 429
   COILS
   Coil (Coil)
   502 - 530
   COILS
   Coil (Coil)
   444 - 465
   COILS
   Coil (Coil)
2. G3DSA:3.10.58...
   887 - 1,006
   GENE3D
   G3DSA:3.10.580.10 (G3DSA:3.10.580.10)
   732 - 860
   GENE3D
   G3DSA:3.10.580.10 (G3DSA:3.10.580.10)
3. G3DSA:3.30.70...
   144 - 242
   GENE3D
   G3DSA:3.30.70.900 (G3DSA:3.30.70.900)
   32 - 143
   GENE3D
   G3DSA:3.30.70.900 (G3DSA:3.30.70.900)
4. PTHR13780 (AMP-ACTI...)
   635 - 1,016
   PANTHER
   PTHR13780 (AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT)
5. PTHR13780:SF13 (SUB...)
   635 - 1,016
   PANTHER
   PTHR13780:SF13 (SUBFAMILY NOT NAMED)
6. SSF54631 (CBS-domai...)
   873 - 1,010
   SUPERFAMILY
   SSF54631 (CBS-domain pair)
   714 - 869
   SUPERFAMILY
   SSF54631 (CBS-domain pair)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0008201 heparin binding
GO:0030554 adenyl nucleotide binding
GO:0050750 low-density lipoprotein particle receptor binding

#### Cellular Component

GO:0005783 endoplasmic reticulum