Protein

## EMLSAP00000007407

Length
1,753 amino acids

### Protein family membership

- Mediator complex, subunit Med22 (IPR009332)

### Domains and repeats

1. Domain
   12 - 49
   - SAP domain (IPR003034)
   307 - 386
   - RNA recognition motif domain (IPR000504)
   891 - 934
   - SAP domain (IPR003034)
   1,160 - 1,238
   - RNA recognition motif domain (IPR000504)
2. Domain
   270 - 392
   - Nucleotide-binding, alpha-beta plait (IPR012677)
   1,128 - 1,241
   - Nucleotide-binding, alpha-beta plait (IPR012677)

1 200 400 600 800 1000 1200 1400 1600 1753

### Detailed signature matches

1. IPR009332
   Mediator complex, subunit Med22
   1. PTHR12434 (FAMILY N...)
      1,609 - 1,753
      PANTHER
      PTHR12434 (FAMILY NOT NAMED)
   2. PF06179 (Med22)
      1,634 - 1,743
      Pfam
      PF06179 (Med22)
2. IPR003034
   SAP domain
   1. G3DSA:1.10.72...
      12 - 49
      GENE3D
      G3DSA:1.10.720.30 (G3DSA:1.10.720.30)
      891 - 934
      GENE3D
      G3DSA:1.10.720.30 (G3DSA:1.10.720.30)
   2. SM00513 (SAP)
      891 - 925
      SMART
      SM00513 (SAP)
      12 - 46
      SMART
      SM00513 (SAP)
   3. PF02037 (SAP)
      891 - 925
      Pfam
      PF02037 (SAP)
      12 - 46
      Pfam
      PF02037 (SAP)
   4. PS50800 (SAP)
      891 - 925
      PROSITE profiles
      PS50800 (SAP)
      12 - 46
      PROSITE profiles
      PS50800 (SAP)
3. IPR012677
   Nucleotide-binding, alpha-beta plait
   1. G3DSA:3.30.70...
      270 - 392
      GENE3D
      G3DSA:3.30.70.330 (G3DSA:3.30.70.330)
      1,128 - 1,241
      GENE3D
      G3DSA:3.30.70.330 (G3DSA:3.30.70.330)
4. IPR000504
   RNA recognition motif domain
   1. SM00360 (RRM)
      308 - 382
      SMART
      SM00360 (RRM)
      1,161 - 1,234
      SMART
      SM00360 (RRM)
   2. PS50102 (RRM)
      307 - 386
      PROSITE profiles
      PS50102 (RRM)
      1,160 - 1,238
      PROSITE profiles
      PS50102 (RRM)

no IPR
Unintegrated signatures

1. Coil
   536 - 548
   COILS
   Coil (Coil)
   1,359 - 1,453
   COILS
   Coil (Coil)
   549 - 588
   COILS
   Coil (Coil)
   88 - 109
   COILS
   Coil (Coil)
   495 - 534
   COILS
   Coil (Coil)
2. PF14259 (RRM_6)
   309 - 379
   Pfam
   PF14259 (RRM_6)
   1,162 - 1,231
   Pfam
   PF14259 (RRM_6)
3. PTHR12434:SF5 (SUBF...)
   1,609 - 1,753
   PANTHER
   PTHR12434:SF5 (SUBFAMILY NOT NAMED)
4. SSF54928 (RNA-bindi...)
   1,153 - 1,244
   SUPERFAMILY
   SSF54928 (RNA-binding domain, RBD)
   298 - 397
   SUPERFAMILY
   SSF54928 (RNA-binding domain, RBD)
5. SSF68906 (SAP domain)
   12 - 48
   SUPERFAMILY
   SSF68906 (SAP domain)
   891 - 928
   SUPERFAMILY
   SSF68906 (SAP domain)

### GO term prediction

#### Biological Process

GO:0006357 regulation of transcription from RNA polymerase II promoter

#### Molecular Function

GO:0000166 nucleotide binding
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0003676 nucleic acid binding

#### Cellular Component

GO:0016592 mediator complex