Protein

## EMLSAP00000004106

Length
461 amino acids

### Protein family membership

- Translation elongation factor EF1A, eukaryotic/archaeal (IPR004539)

### Domains and repeats

1. Domain
   3 - 261
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   335 - 441
   - Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (IPR009001)
     - Translation elongation factor EFTu/EF1A, C-terminal (IPR004160)
2. Domain
   6 - 237
   - Elongation factor, GTP-binding domain (IPR000795)
   243 - 334
   - Translation protein, beta-barrel domain (IPR009000)
     - Translation elongation factor EFTu/EF1A, domain 2 (IPR004161)

1 50 100 150 200 250 300 350 400 461

### Detailed signature matches

1. IPR004539
   Translation elongation factor EF1A, eukaryotic/archaeal
   1. TIGR00483
      1 - 445
      UNKNOWN
      TIGR00483 (TIGR00483)
2. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      3 - 261
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
3. IPR000795
   Elongation factor, GTP-binding domain
   1. PF00009 (GTP_EFTU)
      6 - 237
      Pfam
      PF00009 (GTP_EFTU)
   2. PS00301 (EFACTOR_GTP)
      61 - 76
      PROSITE patterns
      PS00301 (EFACTOR_GTP)
   3. PR00315 (ELONGATNFCT)
      9 - 22
      PRINTS
      PR00315 (ELONGATNFCT)
      148 - 157
      PRINTS
      PR00315 (ELONGATNFCT)
      88 - 98
      PRINTS
      PR00315 (ELONGATNFCT)
      104 - 115
      PRINTS
      PR00315 (ELONGATNFCT)
      68 - 76
      PRINTS
      PR00315 (ELONGATNFCT)
4. IPR009000
   Translation protein, beta-barrel domain
   1. SSF50447 (Translati...)
      243 - 334
      SUPERFAMILY
      SSF50447 (Translation proteins)
5. IPR004161
   Translation elongation factor EFTu/EF1A, domain 2
   1. PF03144 (GTP_EFTU_D2)
      260 - 325
      Pfam
      PF03144 (GTP_EFTU_D2)
6. IPR009001
   Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
   1. SSF50465 (EF-Tu/eEF...)
      337 - 441
      SUPERFAMILY
      SSF50465 (EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain)
7. IPR004160
   Translation elongation factor EFTu/EF1A, C-terminal
   1. PF03143 (GTP_EFTU_D3)
      335 - 440
      Pfam
      PF03143 (GTP_EFTU_D3)

no IPR
Unintegrated signatures

1. G3DSA:2.40.30.10
   350 - 440
   GENE3D
   G3DSA:2.40.30.10 (G3DSA:2.40.30.10)
   246 - 349
   GENE3D
   G3DSA:2.40.30.10 (G3DSA:2.40.30.10)
2. G3DSA:3.40.50...
   3 - 245
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PTHR23115 (TRANSLAT...)
   1 - 445
   PANTHER
   PTHR23115 (TRANSLATION FACTOR)

### GO term prediction

#### Biological Process

GO:0006414 translational elongation

#### Molecular Function

GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding

#### Cellular Component

GO:0005737 cytoplasm