Protein

## EMLSAP00000012413

Length
540 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   30 - 154
   - Prolyl 4-hydroxylase alpha-subunit, N-terminal (IPR013547)
   165 - 253
   - Tetratricopeptide-like helical (IPR011990)
   285 - 298
   - Tetratricopeptide-like helical (IPR011990)
   329 - 512
   - Oxoglutarate/iron-dependent dioxygenase (IPR005123)
     - Prolyl 4-hydroxylase, alpha subunit (IPR006620)

1 50 100 150 200 250 300 350 400 450 500 540

### Detailed signature matches

1. IPR013547
   Prolyl 4-hydroxylase alpha-subunit, N-terminal
   1. PF08336 (P4Ha_N)
      30 - 154
      Pfam
      PF08336 (P4Ha_N)
2. IPR011990
   Tetratricopeptide-like helical
   1. G3DSA:1.25.40.10
      165 - 253
      GENE3D
      G3DSA:1.25.40.10 (G3DSA:1.25.40.10)
      285 - 298
      GENE3D
      G3DSA:1.25.40.10 (G3DSA:1.25.40.10)
3. IPR005123
   Oxoglutarate/iron-dependent dioxygenase
   1. PS51471 (FE2OG_OXY)
      407 - 512
      PROSITE profiles
      PS51471 (FE2OG_OXY)
   2. PF03171 (2OG-FeII_Oxy)
      411 - 511
      Pfam
      PF03171 (2OG-FeII_Oxy)
4. IPR006620
   Prolyl 4-hydroxylase, alpha subunit
   1. SM00702 (P4Hc)
      329 - 511
      SMART
      SM00702 (P4Hc)

no IPR
Unintegrated signatures

1. PTHR10869 (PROLYL 4...)
   1 - 533
   PANTHER
   PTHR10869 (PROLYL 4-HYDROXYLASE ALPHA SUBUNIT)
2. PTHR10869:SF15 (PRO...)
   1 - 533
   PANTHER
   PTHR10869:SF15 (PROLYL 4-HYDROXYLASE ALPHA-1 SUBUNIT-RELATED)

### GO term prediction

#### Biological Process

GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0004656 procollagen-proline 4-dioxygenase activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418 L-ascorbic acid binding

#### Cellular Component

GO:0005783 endoplasmic reticulum