Protein

## EMLSAP00000009608

Length
341 amino acids

### Protein family membership

- Twinfilin (IPR028458)

### Domains and repeats

1. Domain
   4 - 137
   - Actin-binding, cofilin/tropomyosin type (IPR002108)
   174 - 311
   - Actin-binding, cofilin/tropomyosin type (IPR002108)

1 50 100 150 200 250 300 341

### Detailed signature matches

1. IPR028458
   Twinfilin
   1. PTHR13759 (TWINFILIN)
      2 - 341
      PANTHER
      PTHR13759 (TWINFILIN)
2. IPR002108
   Actin-binding, cofilin/tropomyosin type
   1. SM00102 (ADF)
      11 - 137
      SMART
      SM00102 (ADF)
      181 - 311
      SMART
      SM00102 (ADF)
   2. PS51263 (ADF_H)
      4 - 137
      PROSITE profiles
      PS51263 (ADF_H)
      174 - 311
      PROSITE profiles
      PS51263 (ADF_H)
   3. PF00241 (Cofilin_ADF)
      183 - 307
      Pfam
      PF00241 (Cofilin_ADF)
      64 - 130
      Pfam
      PF00241 (Cofilin_ADF)

no IPR
Unintegrated signatures

1. G3DSA:3.40.20.10
   1 - 137
   GENE3D
   G3DSA:3.40.20.10 (G3DSA:3.40.20.10)
   177 - 324
   GENE3D
   G3DSA:3.40.20.10 (G3DSA:3.40.20.10)
2. PTHR13759:SF0 (SUBF...)
   2 - 341
   PANTHER
   PTHR13759:SF0 (SUBFAMILY NOT NAMED)
3. SSF55753 (Actin dep...)
   166 - 314
   SUPERFAMILY
   SSF55753 (Actin depolymerizing proteins)
   1 - 147
   SUPERFAMILY
   SSF55753 (Actin depolymerizing proteins)

### GO term prediction

#### Biological Process

GO:0030837 negative regulation of actin filament polymerization

#### Molecular Function

GO:0003779 actin binding

#### Cellular Component

GO:0005622 intracellular