Protein

## EMLSAP00000011283

Length
896 amino acids

### Protein family membership

- Hly-III-related (IPR004254)

- Peptidase C1A, papain (IPR013128)

### Domains and repeats

1. Domain
   640 - 696
   - Proteinase inhibitor I29, cathepsin propeptide (IPR013201)
   724 - 892
   - Peptidase C1A, papain C-terminal (IPR000668)

1 100 200 300 400 500 600 700 800 896

### Detailed signature matches

1. IPR004254
   Hly-III-related
   1. PF03006 (HlyIII)
      190 - 393
      Pfam
      PF03006 (HlyIII)
2. IPR013128
   Peptidase C1A, papain
   1. PTHR12411 (CYSTEINE...)
      399 - 892
      PANTHER
      PTHR12411 (CYSTEINE PROTEASE FAMILY C1-RELATED)
3. IPR013201
   Proteinase inhibitor I29, cathepsin propeptide
   1. PF08246 (Inhibitor_I29)
      640 - 695
      Pfam
      PF08246 (Inhibitor_I29)
   2. SM00848 (Inhibitor_I29)
      640 - 696
      SMART
      SM00848 (Inhibitor_I29)
4. IPR000668
   Peptidase C1A, papain C-terminal
   1. SM00645 (Pept_C1)
      724 - 892
      SMART
      SM00645 (Pept_C1)
   2. PF00112 (Peptidase_C1)
      760 - 890
      Pfam
      PF00112 (Peptidase_C1)
      724 - 750
      Pfam
      PF00112 (Peptidase_C1)
5. IPR025660
   Cysteine peptidase, histidine active site
   1. PS00639 (THIOL_PROT...)
      839 - 849
      PROSITE patterns
      PS00639 (THIOL_PROTEASE_HIS)
6. IPR025661
   Cysteine peptidase, asparagine active site
   1. PS00640 (THIOL_PROT...)
      856 - 875
      PROSITE patterns
      PS00640 (THIOL_PROTEASE_ASN)

no IPR
Unintegrated signatures

1. G3DSA:3.90.70.10
   633 - 750
   GENE3D
   G3DSA:3.90.70.10 (G3DSA:3.90.70.10)
   765 - 893
   GENE3D
   G3DSA:3.90.70.10 (G3DSA:3.90.70.10)
2. PTHR12411:SF47 (SUB...)
   399 - 892
   PANTHER
   PTHR12411:SF47 (SUBFAMILY NOT NAMED)
3. SSF54001 (Cysteine ...)
   634 - 892
   SUPERFAMILY
   SSF54001 (Cysteine proteinases)
4. TMhelix
   359 - 381
   TMHMM
   TMhelix (TMhelix)
   230 - 252
   TMHMM
   TMhelix (TMhelix)
   325 - 347
   TMHMM
   TMhelix (TMhelix)
   267 - 289
   TMHMM
   TMhelix (TMhelix)
   196 - 218
   TMHMM
   TMhelix (TMhelix)
   296 - 315
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis

#### Molecular Function

GO:0008234 cysteine-type peptidase activity

#### Cellular Component

GO:0016021 integral component of membrane