Protein

## EMLSAP00000008705

Length
1,958 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   1,370 - 1,573
   - Dbl homology (DH) domain (IPR000219)
   1,622 - 1,752
   - Pleckstrin homology domain (IPR001849)

1 200 400 600 800 1000 1200 1400 1600 1800 1958

### Detailed signature matches

1. IPR000219
   Dbl homology (DH) domain
   1. SM00325 (RhoGEF)
      1,383 - 1,569
      SMART
      SM00325 (RhoGEF)
   2. SSF48065 (DBL homol...)
      1,370 - 1,573
      SUPERFAMILY
      SSF48065 (DBL homology domain (DH-domain))
   3. PF00621 (RhoGEF)
      1,384 - 1,569
      Pfam
      PF00621 (RhoGEF)
   4. PS50010 (DH_2)
      1,379 - 1,570
      PROSITE profiles
      PS50010 (DH_2)
   5. G3DSA:1.20.90...
      1,373 - 1,569
      GENE3D
      G3DSA:1.20.900.10 (G3DSA:1.20.900.10)
2. IPR001849
   Pleckstrin homology domain
   1. PS50003 (PH_DOMAIN)
      1,622 - 1,752
      PROSITE profiles
      PS50003 (PH_DOMAIN)

no IPR
Unintegrated signatures

1. Coil
   1,313 - 1,338
   COILS
   Coil (Coil)
   1,550 - 1,574
   COILS
   Coil (Coil)
2. PTHR12673 (FACIOGEN...)
   188 - 1,953
   PANTHER
   PTHR12673 (FACIOGENITAL DYSPLASIA PROTEIN)
3. SignalP-TM
   1 - 12
   SignalP Gram+ prok
   SignalP-TM (SignalP-TM)

### GO term prediction

#### Biological Process

GO:0035023 regulation of Rho protein signal transduction

#### Molecular Function

GO:0005089 Rho guanyl-nucleotide exchange factor activity

#### Cellular Component

None predicted.