Protein

## EMLSAP00000001803

Length
608 amino acids

### Protein family membership

- Aminoacyl-tRNA synthetase, class Ic (IPR002305)
  - Tyrosine-tRNA ligase (IPR002307)
    - Tyrosine-tRNA ligase, archaeal/eukaryotic-type (IPR023617)

### Domains and repeats

1. Domain
   82 - 283
   - Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
   443 - 606
   - Nucleic acid-binding, OB-fold (IPR012340)
     - tRNA-binding domain (IPR002547)

1 100 200 300 400 500 608

### Detailed signature matches

1. IPR002305
   Aminoacyl-tRNA synthetase, class Ic
   1. PF00579 (tRNA-synt_1b)
      109 - 401
      Pfam
      PF00579 (tRNA-synt_1b)
2. IPR002307
   Tyrosine-tRNA ligase
   1. TIGR00234
      86 - 412
      UNKNOWN
      TIGR00234 (TIGR00234)
   2. PR01040 (TRNASYNTHTYR)
      285 - 297
      PRINTS
      PR01040 (TRNASYNTHTYR)
      124 - 146
      PRINTS
      PR01040 (TRNASYNTHTYR)
      235 - 250
      PRINTS
      PR01040 (TRNASYNTHTYR)
      252 - 274
      PRINTS
      PR01040 (TRNASYNTHTYR)
3. IPR023617
   Tyrosine-tRNA ligase, archaeal/eukaryotic-type
   1. PTHR11946:SF8 (TYRO...)
      82 - 570
      PANTHER
      PTHR11946:SF8 (TYROSYL-TRNA SYNTHETASE)
4. IPR014729
   Rossmann-like alpha/beta/alpha sandwich fold
   1. G3DSA:3.40.50...
      82 - 283
      GENE3D
      G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
5. IPR012340
   Nucleic acid-binding, OB-fold
   1. SSF50249 (Nucleic a...)
      444 - 606
      SUPERFAMILY
      SSF50249 (Nucleic acid-binding proteins)
   2. G3DSA:2.40.50...
      445 - 603
      GENE3D
      G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
6. IPR002547
   tRNA-binding domain
   1. PF01588 (tRNA_bind)
      449 - 545
      Pfam
      PF01588 (tRNA_bind)
   2. PS50886 (TRBD)
      443 - 548
      PROSITE profiles
      PS50886 (TRBD)

no IPR
Unintegrated signatures

1. G3DSA:1.10.24...
   284 - 423
   GENE3D
   G3DSA:1.10.240.10 (G3DSA:1.10.240.10)
2. PTHR11946 (ISOLEUCY...)
   82 - 570
   PANTHER
   PTHR11946 (ISOLEUCYL, LEUCYL, TYROSYL, VALYL AND METHIONYL-TRNA SYNTHETASES)
3. SSF52374 (Nucleotid...)
   80 - 412
   SUPERFAMILY
   SSF52374 (Nucleotidylyl transferase)

### GO term prediction

#### Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation

#### Molecular Function

GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding

#### Cellular Component

GO:0005737 cytoplasm