Protein

## EMLSAP00000009722

Length
1,531 amino acids

### Protein family membership

- Transient receptor potential channel, canonical (IPR002153)

### Domains and repeats

1. Domain
   83 - 990
   - Ankyrin repeat-containing domain (IPR020683)
2. Repeat
   90 - 122
   - Ankyrin repeat (IPR002110)
   123 - 152
   - Ankyrin repeat (IPR002110)
   157 - 190
   - Ankyrin repeat (IPR002110)
   195 - 224
   - Ankyrin repeat (IPR002110)
   231 - 263
   - Ankyrin repeat (IPR002110)
   296 - 328
   - Ankyrin repeat (IPR002110)
   330 - 365
   - Ankyrin repeat (IPR002110)
   366 - 398
   - Ankyrin repeat (IPR002110)
   399 - 432
   - Ankyrin repeat (IPR002110)
   440 - 480
   - Ankyrin repeat (IPR002110)
   483 - 514
   - Ankyrin repeat (IPR002110)
   522 - 554
   - Ankyrin repeat (IPR002110)
   555 - 587
   - Ankyrin repeat (IPR002110)
   588 - 618
   - Ankyrin repeat (IPR002110)
   622 - 654
   - Ankyrin repeat (IPR002110)
   655 - 687
   - Ankyrin repeat (IPR002110)
   689 - 718
   - Ankyrin repeat (IPR002110)
   725 - 757
   - Ankyrin repeat (IPR002110)
   758 - 790
   - Ankyrin repeat (IPR002110)
   792 - 822
   - Ankyrin repeat (IPR002110)
   840 - 869
   - Ankyrin repeat (IPR002110)
   875 - 904
   - Ankyrin repeat (IPR002110)
   928 - 960
   - Ankyrin repeat (IPR002110)
   961 - 990
   - Ankyrin repeat (IPR002110)
3. Repeat
   263 - 295
   - Ankyrin repeat (IPR002110)

1 200 400 600 800 1000 1200 1400 1531

### Detailed signature matches

1. IPR002153
   Transient receptor potential channel, canonical
   1. PR01097 (TRNSRECEPTRP)
      1,377 - 1,398
      PRINTS
      PR01097 (TRNSRECEPTRP)
      1,399 - 1,412
      PRINTS
      PR01097 (TRNSRECEPTRP)
2. IPR020683
   Ankyrin repeat-containing domain
   1. PS50297 (ANK_REP_RE...)
      90 - 983
      PROSITE profiles
      PS50297 (ANK_REP_REGION)
   2. G3DSA:1.25.40.20
      612 - 987
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
      206 - 447
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
      85 - 205
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
      448 - 611
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
   3. PF12796 (Ank_2)
      845 - 927
      Pfam
      PF12796 (Ank_2)
      695 - 786
      Pfam
      PF12796 (Ank_2)
      932 - 987
      Pfam
      PF12796 (Ank_2)
      527 - 618
      Pfam
      PF12796 (Ank_2)
      83 - 152
      Pfam
      PF12796 (Ank_2)
      335 - 422
      Pfam
      PF12796 (Ank_2)
      236 - 326
      Pfam
      PF12796 (Ank_2)
   4. SSF48403 (Ankyrin r...)
      87 - 456
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
      793 - 990
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
      435 - 824
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
3. IPR002110
   Ankyrin repeat
   1. SM00248 (ANK)
      157 - 190
      SMART
      SM00248 (ANK)
      792 - 822
      SMART
      SM00248 (ANK)
      522 - 551
      SMART
      SM00248 (ANK)
      263 - 292
      SMART
      SM00248 (ANK)
      123 - 152
      SMART
      SM00248 (ANK)
      655 - 684
      SMART
      SM00248 (ANK)
      689 - 718
      SMART
      SM00248 (ANK)
      195 - 224
      SMART
      SM00248 (ANK)
      555 - 584
      SMART
      SM00248 (ANK)
      725 - 754
      SMART
      SM00248 (ANK)
      928 - 957
      SMART
      SM00248 (ANK)
      90 - 119
      SMART
      SM00248 (ANK)
      961 - 990
      SMART
      SM00248 (ANK)
      440 - 478
      SMART
      SM00248 (ANK)
      366 - 395
      SMART
      SM00248 (ANK)
      296 - 325
      SMART
      SM00248 (ANK)
      330 - 362
      SMART
      SM00248 (ANK)
      840 - 869
      SMART
      SM00248 (ANK)
      588 - 618
      SMART
      SM00248 (ANK)
      231 - 260
      SMART
      SM00248 (ANK)
      399 - 432
      SMART
      SM00248 (ANK)
      875 - 904
      SMART
      SM00248 (ANK)
      483 - 514
      SMART
      SM00248 (ANK)
      622 - 651
      SMART
      SM00248 (ANK)
      758 - 787
      SMART
      SM00248 (ANK)
   2. PR01415 (ANKYRIN)
      944 - 958
      PRINTS
      PR01415 (ANKYRIN)
      556 - 571
      PRINTS
      PR01415 (ANKYRIN)
   3. PS50088 (ANK_REPEAT)
      231 - 263
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      655 - 687
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      296 - 328
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      399 - 421
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      330 - 365
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      840 - 862
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      928 - 960
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      588 - 611
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      725 - 757
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      792 - 813
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      622 - 654
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      366 - 398
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      90 - 122
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      263 - 295
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      758 - 790
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      522 - 554
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      555 - 587
      PROSITE profiles
      PS50088 (ANK_REPEAT)
   4. PF00023 (Ank)
      793 - 815
      Pfam
      PF00023 (Ank)
      441 - 480
      Pfam
      PF00023 (Ank)

no IPR
Unintegrated signatures

1. PF13637 (Ank_4)
   625 - 676
   Pfam
   PF13637 (Ank_4)
2. PTHR24121 (NO MECHA...)
   98 - 1,531
   PANTHER
   PTHR24121 (NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED)
3. PTHR24121:SF0 (NO M...)
   98 - 1,531
   PANTHER
   PTHR24121:SF0 (NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED)
4. TMhelix
   1,187 - 1,205
   TMHMM
   TMhelix (TMhelix)
   1,217 - 1,239
   TMHMM
   TMhelix (TMhelix)
   1,119 - 1,141
   TMHMM
   TMhelix (TMhelix)
   1,280 - 1,302
   TMHMM
   TMhelix (TMhelix)
   1,374 - 1,396
   TMHMM
   TMhelix (TMhelix)
   1,426 - 1,445
   TMHMM
   TMhelix (TMhelix)
   1,161 - 1,183
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0070588 calcium ion transmembrane transport

#### Molecular Function

GO:0005262 calcium channel activity
GO:0005515 protein binding

#### Cellular Component

GO:0016020 membrane