Protein

## EMLSAP00000012962

Length
555 amino acids

### Protein family membership

- Cystathionine beta-synthase (IPR005857)

### Domains and repeats

1. Domain
   73 - 394
   - Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily (IPR001926)
   418 - 474
   - CBS domain (IPR000644)
   483 - 551
   - CBS domain (IPR000644)

1 100 200 300 400 500 555

### Detailed signature matches

1. IPR005857
   Cystathionine beta-synthase
   1. TIGR01137
      78 - 543
      UNKNOWN
      TIGR01137 (TIGR01137)
2. IPR001926
   Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily
   1. PF00291 (PALP)
      84 - 378
      Pfam
      PF00291 (PALP)
   2. SSF53686 (Tryptopha...)
      73 - 394
      SUPERFAMILY
      SSF53686 (Tryptophan synthase beta subunit-like PLP-dependent enzymes)
3. IPR000644
   CBS domain
   1. SM00116 (CBS)
      421 - 469
      SMART
      SM00116 (CBS)
   2. PS51371 (CBS)
      483 - 551
      PROSITE profiles
      PS51371 (CBS)
      418 - 474
      PROSITE profiles
      PS51371 (CBS)
   3. PF00571 (CBS)
      421 - 469
      Pfam
      PF00571 (CBS)
4. IPR001216
   Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site
   1. PS00901 (CYS_SYNTHASE)
      110 - 128
      PROSITE patterns
      PS00901 (CYS_SYNTHASE)

no IPR
Unintegrated signatures

1. G3DSA:3.10.58...
   412 - 546
   GENE3D
   G3DSA:3.10.580.10 (G3DSA:3.10.580.10)
2. G3DSA:3.40.50...
   217 - 396
   GENE3D
   G3DSA:3.40.50.1100 (G3DSA:3.40.50.1100)
   115 - 216
   GENE3D
   G3DSA:3.40.50.1100 (G3DSA:3.40.50.1100)
3. PTHR10314 (SER/THR ...)
   47 - 402
   PANTHER
   PTHR10314 (SER/THR DEHYDRATASE, TRP SYNTHASE)
4. PTHR10314:SF18 (CYS...)
   47 - 402
   PANTHER
   PTHR10314:SF18 (CYSTATHIONINE BETA-SYNTHASE)
5. SSF54631 (CBS-domai...)
   413 - 543
   SUPERFAMILY
   SSF54631 (CBS-domain pair)

### GO term prediction

#### Biological Process

GO:0006535 cysteine biosynthetic process from serine
GO:0019343 cysteine biosynthetic process via cystathionine

#### Molecular Function

GO:0004122 cystathionine beta-synthase activity
GO:0030554 adenyl nucleotide binding

#### Cellular Component

GO:0005737 cytoplasm