Protein

## EMLSAP00000011591

Length
1,186 amino acids

### Protein family membership

- Protein of unknown function DUF268, Caenorhabditis species (IPR004951)

### Domains and repeats

1. Domain
   21 - 234
   - Arfaptin homology (AH) domain/BAR domain (IPR027267)
     - BAR domain (IPR004148)
   286 - 392
   - Pleckstrin homology-like domain (IPR011993)
     - Pleckstrin homology domain (IPR001849)
   404 - 600
   - Rho GTPase activation protein (IPR008936)
     - Rho GTPase-activating protein domain (IPR000198)
   858 - 921
   - Src homology-3 domain (IPR001452)

1 200 400 600 800 1000 1186

### Detailed signature matches

1. IPR004951
   Protein of unknown function DUF268, Caenorhabditis species
   1. PF03269 (DUF268)
      1,076 - 1,174
      Pfam
      PF03269 (DUF268)
2. IPR027267
   Arfaptin homology (AH) domain/BAR domain
   1. G3DSA:1.20.12...
      21 - 234
      GENE3D
      G3DSA:1.20.1270.60 (G3DSA:1.20.1270.60)
3. IPR004148
   BAR domain
   1. PF03114 (BAR)
      24 - 226
      Pfam
      PF03114 (BAR)
4. IPR011993
   Pleckstrin homology-like domain
   1. G3DSA:2.30.29.30
      289 - 386
      GENE3D
      G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
5. IPR001849
   Pleckstrin homology domain
   1. SM00233 (PH)
      287 - 392
      SMART
      SM00233 (PH)
   2. PS50003 (PH_DOMAIN)
      286 - 390
      PROSITE profiles
      PS50003 (PH_DOMAIN)
6. IPR008936
   Rho GTPase activation protein
   1. SSF48350 (GTPase ac...)
      413 - 591
      SUPERFAMILY
      SSF48350 (GTPase activation domain, GAP)
7. IPR000198
   Rho GTPase-activating protein domain
   1. SM00324 (RhoGAP)
      408 - 586
      SMART
      SM00324 (RhoGAP)
   2. G3DSA:1.10.55...
      413 - 600
      GENE3D
      G3DSA:1.10.555.10 (G3DSA:1.10.555.10)
   3. PF00620 (RhoGAP)
      413 - 562
      Pfam
      PF00620 (RhoGAP)
   4. PS50238 (RHOGAP)
      404 - 589
      PROSITE profiles
      PS50238 (RHOGAP)
8. IPR001452
   Src homology-3 domain
   1. SM00326 (SH3)
      864 - 920
      SMART
      SM00326 (SH3)
   2. SSF50044 (SH3-domain)
      858 - 918
      SUPERFAMILY
      SSF50044 (SH3-domain)
   3. PS50002 (SH3)
      861 - 921
      PROSITE profiles
      PS50002 (SH3)

no IPR
Unintegrated signatures

1. Coil
   23 - 51
   COILS
   Coil (Coil)
   88 - 109
   COILS
   Coil (Coil)
2. G3DSA:2.30.30.40
   864 - 918
   GENE3D
   G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
3. PF14604 (SH3_9)
   879 - 917
   Pfam
   PF14604 (SH3_9)
4. PTHR12552 (OLIGOPHR...)
   3 - 920
   PANTHER
   PTHR12552 (OLIGOPHRENIN 1)
5. PTHR12552:SF1 (GRAF...)
   3 - 920
   PANTHER
   PTHR12552:SF1 (GRAF-RELATED)
6. SSF103657 (BAR/IMD ...)
   6 - 310
   SUPERFAMILY
   SSF103657 (BAR/IMD domain-like)
7. SSF50729 (PH domain...)
   287 - 387
   SUPERFAMILY
   SSF50729 (PH domain-like)
8. TMhelix
   915 - 937
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0007165 signal transduction

#### Molecular Function

GO:0005515 protein binding

#### Cellular Component

GO:0005622 intracellular
GO:0005737 cytoplasm