Protein

## EMLSAP00000009470

Length
1,743 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   175 - 443
   - Armadillo-type fold (IPR016024)
     - Armadillo-like helical (IPR011989)
   456 - 540
   - WWE domain (IPR004170)
     - WWE domain, subgroup (IPR018123)
   559 - 668
   - Armadillo-type fold (IPR016024)
     - Armadillo-like helical (IPR011989)
   1,323 - 1,743
   - HECT (IPR000569)

1 200 400 600 800 1000 1200 1400 1600 1743

### Detailed signature matches

1. IPR016024
   Armadillo-type fold
   1. SSF48371 (ARM repeat)
      178 - 443
      SUPERFAMILY
      SSF48371 (ARM repeat)
      559 - 668
      SUPERFAMILY
      SSF48371 (ARM repeat)
2. IPR011989
   Armadillo-like helical
   1. G3DSA:1.25.10.10
      175 - 433
      GENE3D
      G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
      562 - 668
      GENE3D
      G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
3. IPR004170
   WWE domain
   1. PF02825 (WWE)
      466 - 532
      Pfam
      PF02825 (WWE)
   2. PS50918 (WWE)
      456 - 532
      PROSITE profiles
      PS50918 (WWE)
4. IPR018123
   WWE domain, subgroup
   1. SM00678 (WWE)
      465 - 540
      SMART
      SM00678 (WWE)
5. IPR000569
   HECT
   1. SSF56204 (Hect, E3 ...)
      1,323 - 1,392
      SUPERFAMILY
      SSF56204 (Hect, E3 ligase catalytic domain)
      1,425 - 1,736
      SUPERFAMILY
      SSF56204 (Hect, E3 ligase catalytic domain)
   2. SM00119 (HECTc)
      1,339 - 1,743
      SMART
      SM00119 (HECTc)
   3. PS50237 (HECT)
      1,331 - 1,743
      PROSITE profiles
      PS50237 (HECT)
   4. PF00632 (HECT)
      1,372 - 1,743
      Pfam
      PF00632 (HECT)

no IPR
Unintegrated signatures

1. G3DSA:3.30.21...
   1,481 - 1,577
   GENE3D
   G3DSA:3.30.2160.10 (G3DSA:3.30.2160.10)
2. PTHR11254 (HECT DOM...)
   108 - 1,743
   PANTHER
   PTHR11254 (HECT DOMAIN UBIQUITIN-PROTEIN LIGASE)
3. PTHR11254:SF72 (THY...)
   108 - 1,743
   PANTHER
   PTHR11254:SF72 (THYROID RECEPTOR INTERACTING PROTEIN 12 (TRIP12))
4. SSF117839 (WWE domain)
   442 - 534
   SUPERFAMILY
   SSF117839 (WWE domain)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0004842 ubiquitin-protein ligase activity
GO:0005488 binding
GO:0008270 zinc ion binding

#### Cellular Component

None predicted.