Protein

## EMLSAP00000006628

Length
648 amino acids

### Protein family membership

- AP endonuclease 1 (IPR004808)

### Domains and repeats

1. Domain
   1 - 88
   - Zinc finger, C2CH-type (IPR006612)
   438 - 646
   - Endonuclease/exonuclease/phosphatase (IPR005135)

1 100 200 300 400 500 648

### Detailed signature matches

1. IPR004808
   AP endonuclease 1
   1. PS51435 (AP_NUCLEAS...)
      368 - 648
      PROSITE profiles
      PS51435 (AP_NUCLEASE_F1_4)
   2. PTHR22748 (AP ENDON...)
      362 - 646
      PANTHER
      PTHR22748 (AP ENDONUCLEASE)
   3. TIGR00633
      440 - 646
      UNKNOWN
      TIGR00633 (TIGR00633)
2. IPR006612
   Zinc finger, C2CH-type
   1. SM00692 (DM3)
      24 - 88
      SMART
      SM00692 (DM3)
   2. PS50950 (ZF_THAP)
      1 - 83
      PROSITE profiles
      PS50950 (ZF_THAP)
   3. SM00980 (THAP)
      2 - 86
      SMART
      SM00980 (THAP)
   4. PF05485 (THAP)
      3 - 85
      Pfam
      PF05485 (THAP)
3. IPR005135
   Endonuclease/exonuclease/phosphatase
   1. G3DSA:3.60.10.10
      438 - 645
      GENE3D
      G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
   2. PF03372 (Exo_endo_phos)
      448 - 639
      Pfam
      PF03372 (Exo_endo_phos)
   3. SSF56219 (DNase I-like)
      445 - 646
      SUPERFAMILY
      SSF56219 (DNase I-like)
4. IPR020848
   AP endonuclease 1, conserved site
   1. PS00727 (AP_NUCLEAS...)
      580 - 596
      PROSITE patterns
      PS00727 (AP_NUCLEASE_F1_2)
   2. PS00728 (AP_NUCLEAS...)
      606 - 617
      PROSITE patterns
      PS00728 (AP_NUCLEASE_F1_3)

no IPR
Unintegrated signatures

1. Coil
   151 - 172
   COILS
   Coil (Coil)
   113 - 134
   COILS
   Coil (Coil)
2. PTHR22748:SF0 (SUBF...)
   362 - 646
   PANTHER
   PTHR22748:SF0 (SUBFAMILY NOT NAMED)
3. SSF57716 (Glucocort...)
   1 - 86
   SUPERFAMILY
   SSF57716 (Glucocorticoid receptor-like (DNA-binding domain))
4. TIGR00195
   440 - 644
   UNKNOWN
   TIGR00195 (TIGR00195)

### GO term prediction

#### Biological Process

GO:0006281 DNA repair

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0004519 endonuclease activity

#### Cellular Component

GO:0005622 intracellular