Protein

## EMLSAP00000000440

Length
454 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   179 - 408
   - Peptidase M12B, ADAM/reprolysin (IPR001590)
2. Domain
   180 - 412
   - Metallopeptidase, catalytic domain (IPR024079)

1 50 100 150 200 250 300 350 400 454

### Detailed signature matches

1. IPR001590
   Peptidase M12B, ADAM/reprolysin
   1. PS50215 (ADAM_MEPRO)
      179 - 408
      PROSITE profiles
      PS50215 (ADAM_MEPRO)
2. IPR024079
   Metallopeptidase, catalytic domain
   1. G3DSA:3.40.39...
      180 - 412
      GENE3D
      G3DSA:3.40.390.10 (G3DSA:3.40.390.10)

no IPR
Unintegrated signatures

1. PF13688 (Reprolysin_5)
   181 - 385
   Pfam
   PF13688 (Reprolysin_5)
2. PTHR11905 (ADAM (A ...)
   72 - 417
   PANTHER
   PTHR11905 (ADAM (A DISINTEGRIN AND METALLOPROTEASE DOMAIN))
3. SSF55486 (Metallopr...)
   180 - 397
   SUPERFAMILY
   SSF55486 (Metalloproteases ("zincins"), catalytic domain)
4. TMhelix
   5 - 27
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis

#### Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity

#### Cellular Component

None predicted.