Protein

## EMLSAP00000007092

Length
981 amino acids

### Protein family membership

- Pyruvate carboxylase (IPR005930)

### Domains and repeats

1. Domain
   1 - 284
   - Biotin carboxylation domain (IPR011764)
   913 - 949
   - Biotin/lipoyl attachment (IPR000089)
2. Domain
   1 - 35
   - ATP-grasp fold, subdomain 1 (IPR013815)
   37 - 285
   - ATP-grasp fold, subdomain 2 (IPR013816)
   661 - 861
   - Carboxylase, conserved domain (IPR003379)
3. Domain
   1 - 156
   - ATP-grasp fold (IPR011761)
     - Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain (IPR005479)
   168 - 286
   - Rudiment single hybrid motif (IPR011054)
     - Biotin carboxylase, C-terminal (IPR005482)
   339 - 650
   - Aldolase-type TIM barrel (IPR013785)
     - Pyruvate carboxyltransferase (IPR000891)
   784 - 820
   - Homeodomain-like (IPR009057)
   901 - 949
   - Single hybrid motif (IPR011053)

1 100 200 300 400 500 600 700 800 900 981

### Detailed signature matches

1. IPR005930
   Pyruvate carboxylase
   1. PTHR18866:SF10 (PYR...)
      1 - 948
      PANTHER
      PTHR18866:SF10 (PYRUVATE CARBOXYLASE)
   2. TIGR01235
      1 - 953
      UNKNOWN
      TIGR01235 (TIGR01235)
2. IPR013815
   ATP-grasp fold, subdomain 1
   1. G3DSA:3.30.14...
      1 - 35
      GENE3D
      G3DSA:3.30.1490.20 (G3DSA:3.30.1490.20)
3. IPR011764
   Biotin carboxylation domain
   1. PS50979 (BC)
      1 - 284
      PROSITE profiles
      PS50979 (BC)
4. IPR011761
   ATP-grasp fold
   1. PS50975 (ATP_GRASP)
      30 - 151
      PROSITE profiles
      PS50975 (ATP_GRASP)
5. IPR005479
   Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
   1. PF02786 (CPSase_L_D2)
      1 - 156
      Pfam
      PF02786 (CPSase_L_D2)
   2. PS00867 (CPSASE_2)
      120 - 127
      PROSITE patterns
      PS00867 (CPSASE_2)
6. IPR013816
   ATP-grasp fold, subdomain 2
   1. G3DSA:3.30.47...
      37 - 285
      GENE3D
      G3DSA:3.30.470.20 (G3DSA:3.30.470.20)
7. IPR011054
   Rudiment single hybrid motif
   1. SSF51246 (Rudiment ...)
      168 - 286
      SUPERFAMILY
      SSF51246 (Rudiment single hybrid motif)
8. IPR005482
   Biotin carboxylase, C-terminal
   1. PF02785 (Biotin_carb_C)
      173 - 280
      Pfam
      PF02785 (Biotin_carb_C)
   2. SM00878 (Biotin_carb_C)
      173 - 280
      SMART
      SM00878 (Biotin_carb_C)
9. IPR013785
   Aldolase-type TIM barrel
   1. G3DSA:3.20.20.70
      339 - 650
      GENE3D
      G3DSA:3.20.20.70 (G3DSA:3.20.20.70)
10. IPR000891
    Pyruvate carboxyltransferase
    1. PF00682 (HMGL-like)
       402 - 618
       Pfam
       PF00682 (HMGL-like)
    2. PS50991 (PYR_CT)
       361 - 632
       PROSITE profiles
       PS50991 (PYR_CT)
11. IPR003379
    Carboxylase, conserved domain
    1. PF02436 (PYC_OADA)
       661 - 861
       Pfam
       PF02436 (PYC_OADA)
12. IPR009057
    Homeodomain-like
    1. G3DSA:1.10.10.60
       784 - 820
       GENE3D
       G3DSA:1.10.10.60 (G3DSA:1.10.10.60)
13. IPR011053
    Single hybrid motif
    1. SSF51230 (Single hy...)
       901 - 949
       SUPERFAMILY
       SSF51230 (Single hybrid motif)
14. IPR000089
    Biotin/lipoyl attachment
    1. PF00364 (Biotin_lipoyl)
       913 - 949
       Pfam
       PF00364 (Biotin_lipoyl)

no IPR
Unintegrated signatures

1. G3DSA:2.40.50...
   904 - 949
   GENE3D
   G3DSA:2.40.50.100 (G3DSA:2.40.50.100)
2. G3DSA:3.10.60...
   821 - 896
   GENE3D
   G3DSA:3.10.600.10 (G3DSA:3.10.600.10)
3. PTHR18866 (CARBOXYL...)
   1 - 948
   PANTHER
   PTHR18866 (CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE)
4. SSF51569 (Aldolase)
   355 - 666
   SUPERFAMILY
   SSF51569 (Aldolase)
5. SSF56059 (Glutathio...)
   1 - 186
   SUPERFAMILY
   SSF56059 (Glutathione synthetase ATP-binding domain-like)
6. SSF89000 (post-HMGL...)
   666 - 842
   SUPERFAMILY
   SSF89000 (post-HMGL domain-like)
7. TMhelix
   952 - 974
   TMHMM
   TMhelix (TMhelix)

### GO term prediction

#### Biological Process

GO:0006094 gluconeogenesis

#### Molecular Function

GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004075 biotin carboxylase activity
GO:0004736 pyruvate carboxylase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding

#### Cellular Component

None predicted.