Protein

## EMLSAP00000008539

Length
3,704 amino acids

### Protein family membership

- Dynein heavy chain (IPR026983)

### Domains and repeats

1. Domain
   727 - 1,002
   - Dynein heavy chain, domain-2 (IPR013602)
   1,441 - 1,574
   - ATPase, dynein-related, AAA domain (IPR011704)
   2,094 - 2,175
   - Dynein heavy chain, P-loop containing D4 domain (IPR024317)
   2,183 - 2,318
   - Dynein heavy chain, P-loop containing D4 domain (IPR024317)
2. Domain
   1,140 - 1,362
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   1,432 - 1,654
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   1,794 - 2,016
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   2,086 - 2,327
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   2,335 - 2,682
   - Dynein heavy chain, coiled coil stalk (IPR024743)
   3,089 - 3,704
   - Dynein heavy chain domain (IPR004273)

1 500 1000 1500 2000 2500 3000 3704

### Detailed signature matches

1. IPR026983
   Dynein heavy chain
   1. PTHR10676 (DYNEIN H...)
      28 - 3,704
      PANTHER
      PTHR10676 (DYNEIN HEAVY CHAIN FAMILY PROTEIN)
2. IPR013602
   Dynein heavy chain, domain-2
   1. PF08393 (DHC_N2)
      727 - 1,002
      Pfam
      PF08393 (DHC_N2)
3. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      2,086 - 2,327
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      1,432 - 1,654
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      1,140 - 1,362
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      1,794 - 2,016
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
4. IPR011704
   ATPase, dynein-related, AAA domain
   1. PF07728 (AAA_5)
      1,441 - 1,574
      Pfam
      PF07728 (AAA_5)
5. IPR024317
   Dynein heavy chain, P-loop containing D4 domain
   1. PF12780 (AAA_8)
      2,183 - 2,318
      Pfam
      PF12780 (AAA_8)
      2,094 - 2,175
      Pfam
      PF12780 (AAA_8)
6. IPR024743
   Dynein heavy chain, coiled coil stalk
   1. PF12777 (MT)
      2,335 - 2,682
      Pfam
      PF12777 (MT)
7. IPR004273
   Dynein heavy chain domain
   1. PF03028 (Dynein_heavy)
      3,089 - 3,704
      Pfam
      PF03028 (Dynein_heavy)

no IPR
Unintegrated signatures

1. Coil
   604 - 625
   COILS
   Coil (Coil)
   3,483 - 3,504
   COILS
   Coil (Coil)
   571 - 592
   COILS
   Coil (Coil)
   2,587 - 2,632
   COILS
   Coil (Coil)
2. G3DSA:3.40.50...
   2,089 - 2,269
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   1,787 - 1,907
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   1,140 - 1,298
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   1,379 - 1,582
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
3. PF12774 (AAA_6)
   1,126 - 1,356
   Pfam
   PF12774 (AAA_6)
4. PF12775 (AAA_7)
   1,776 - 1,904
   Pfam
   PF12775 (AAA_7)
   1,906 - 1,995
   Pfam
   PF12775 (AAA_7)
5. PF12781 (AAA_9)
   2,706 - 2,934
   Pfam
   PF12781 (AAA_9)
6. PTHR10676:SF138 (DY...)
   28 - 3,704
   PANTHER
   PTHR10676:SF138 (DYNEIN HEAVY CHAIN FAMILY PROTEIN)

### GO term prediction

#### Biological Process

GO:0007018 microtubule-based movement

#### Molecular Function

GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0016887 ATPase activity

#### Cellular Component

GO:0030286 dynein complex