Protein

## EMLSAP00000000899

Length
645 amino acids

### Protein family membership

- Malic oxidoreductase (IPR001891)

### Domains and repeats

1. Domain
   27 - 298
   - Malic enzyme, N-terminal domain (IPR012301)
   299 - 638
   - NAD(P)-binding domain (IPR016040)
     - Malic enzyme, NAD-binding (IPR012302)

1 100 200 300 400 500 645

### Detailed signature matches

1. IPR001891
   Malic oxidoreductase
   1. PIRSF000106 (ME)
      10 - 639
      PIRSF
      PIRSF000106 (ME)
   2. PR00072 (MALOXRDTASE)
      272 - 290
      PRINTS
      PR00072 (MALOXRDTASE)
      177 - 206
      PRINTS
      PR00072 (MALOXRDTASE)
      213 - 235
      PRINTS
      PR00072 (MALOXRDTASE)
      331 - 347
      PRINTS
      PR00072 (MALOXRDTASE)
      117 - 141
      PRINTS
      PR00072 (MALOXRDTASE)
      297 - 313
      PRINTS
      PR00072 (MALOXRDTASE)
2. IPR012301
   Malic enzyme, N-terminal domain
   1. G3DSA:3.40.50...
      27 - 298
      GENE3D
      G3DSA:3.40.50.10380 (G3DSA:3.40.50.10380)
   2. PF00390 (malic)
      111 - 291
      Pfam
      PF00390 (malic)
3. IPR016040
   NAD(P)-binding domain
   1. G3DSA:3.40.50...
      299 - 400
      GENE3D
      G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
      437 - 638
      GENE3D
      G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
4. IPR012302
   Malic enzyme, NAD-binding
   1. SM00919 (Malic_M)
      301 - 597
      SMART
      SM00919 (Malic_M)
   2. PF03949 (Malic_M)
      301 - 597
      Pfam
      PF03949 (Malic_M)

no IPR
Unintegrated signatures

1. PTHR23406 (MALIC EN...)
   20 - 637
   PANTHER
   PTHR23406 (MALIC ENZYME-RELATED)
2. PTHR23406:SF2 (MALI...)
   20 - 637
   PANTHER
   PTHR23406:SF2 (MALIC ENZYME)
3. SSF51735 (NAD(P)-bi...)
   436 - 638
   SUPERFAMILY
   SSF51735 (NAD(P)-binding Rossmann-fold domains)
   301 - 391
   SUPERFAMILY
   SSF51735 (NAD(P)-binding Rossmann-fold domains)
4. SSF53223 (Aminoacid...)
   21 - 300
   SUPERFAMILY
   SSF53223 (Aminoacid dehydrogenase-like, N-terminal domain)

### GO term prediction

#### Biological Process

GO:0006108 malate metabolic process
GO:0055114 oxidation-reduction process

#### Molecular Function

GO:0004470 malic enzyme activity
GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0051287 NAD binding

#### Cellular Component

None predicted.