Protein

## EMLSAP00000002060

Length
667 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   207 - 560
   - Cullin, N-terminal (IPR001373)
   605 - 665
   - Anaphase-promoting complex subunit 2, C-terminal (IPR014786)
2. Domain
   323 - 567
   - Cullin homology (IPR016158)
   594 - 666
   - Winged helix-turn-helix DNA-binding domain (IPR011991)

1 100 200 300 400 500 600 667

### Detailed signature matches

1. IPR001373
   Cullin, N-terminal
   1. PF00888 (Cullin)
      207 - 560
      Pfam
      PF00888 (Cullin)
2. IPR016158
   Cullin homology
   1. PS50069 (CULLIN_2)
      349 - 546
      PROSITE profiles
      PS50069 (CULLIN_2)
   2. SSF75632 (Cullin ho...)
      323 - 567
      SUPERFAMILY
      SSF75632 (Cullin homology domain)
   3. SM00182 (CULLIN)
      347 - 496
      SMART
      SM00182 (CULLIN)
3. IPR011991
   Winged helix-turn-helix DNA-binding domain
   1. G3DSA:1.10.10.10
      594 - 666
      GENE3D
      G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
4. IPR014786
   Anaphase-promoting complex subunit 2, C-terminal
   1. SM01013 (APC2)
      605 - 665
      SMART
      SM01013 (APC2)
   2. PF08672 (APC2)
      605 - 665
      Pfam
      PF08672 (APC2)

no IPR
Unintegrated signatures

1. G3DSA:1.20.13...
   345 - 418
   GENE3D
   G3DSA:1.20.1310.10 (G3DSA:1.20.1310.10)
2. G3DSA:4.10.10...
   436 - 505
   GENE3D
   G3DSA:4.10.1030.10 (G3DSA:4.10.1030.10)
3. PTHR11932 (CULLIN)
   134 - 662
   PANTHER
   PTHR11932 (CULLIN)
4. PTHR11932:SF5 (ANAP...)
   134 - 662
   PANTHER
   PTHR11932:SF5 (ANAPHASE-PROMOTING COMPLEX SUBUNIT 2)
5. SSF46785 ("Winged h...)
   595 - 666
   SUPERFAMILY
   SSF46785 ("Winged helix" DNA-binding domain)

### GO term prediction

#### Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

#### Molecular Function

GO:0031625 ubiquitin protein ligase binding

#### Cellular Component

GO:0031461 cullin-RING ubiquitin ligase complex