Protein

## EMLSAP00000011629

Length
1,221 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   59 - 454
   - Synaptojanin, N-terminal (IPR002013)
   514 - 864
   - Endonuclease/exonuclease/phosphatase (IPR005135)
     - Inositol polyphosphate-related phosphatase (IPR000300)
   866 - 951
   - Nucleotide-binding, alpha-beta plait (IPR012677)
2. Domain
   844 - 969
   - Domain of unknown function DUF1866 (IPR015047)

1 200 400 600 800 1000 1221

### Detailed signature matches

1. IPR002013
   Synaptojanin, N-terminal
   1. PF02383 (Syja_N)
      59 - 355
      Pfam
      PF02383 (Syja_N)
   2. PS50275 (SAC)
      119 - 454
      PROSITE profiles
      PS50275 (SAC)
2. IPR005135
   Endonuclease/exonuclease/phosphatase
   1. G3DSA:3.60.10.10
      516 - 863
      GENE3D
      G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
   2. PF03372 (Exo_endo_phos)
      529 - 836
      Pfam
      PF03372 (Exo_endo_phos)
   3. SSF56219 (DNase I-like)
      514 - 864
      SUPERFAMILY
      SSF56219 (DNase I-like)
3. IPR000300
   Inositol polyphosphate-related phosphatase
   1. SM00128 (IPPc)
      522 - 851
      SMART
      SM00128 (IPPc)
4. IPR015047
   Domain of unknown function DUF1866
   1. PF08952 (DUF1866)
      844 - 969
      Pfam
      PF08952 (DUF1866)
5. IPR012677
   Nucleotide-binding, alpha-beta plait
   1. G3DSA:3.30.70...
      866 - 951
      GENE3D
      G3DSA:3.30.70.330 (G3DSA:3.30.70.330)

no IPR
Unintegrated signatures

1. Coil
   352 - 373
   COILS
   Coil (Coil)
2. PTHR11200 (INOSITOL...)
   44 - 1,069
   PANTHER
   PTHR11200 (INOSITOL 5-PHOSPHATASE)
3. PTHR11200:SF10 (SYN...)
   44 - 1,069
   PANTHER
   PTHR11200:SF10 (SYNAPTOJANIN)

### GO term prediction

#### Biological Process

GO:0046856 phosphatidylinositol dephosphorylation

#### Molecular Function

GO:0000166 nucleotide binding
GO:0042578 phosphoric ester hydrolase activity

#### Cellular Component

None predicted.