Protein

## EMLSAP00000012191

Length
488 amino acids

### Protein family membership

- Protein disulphide isomerase (IPR005792)

- Thioredoxin (IPR005746)

### Domains and repeats

1. Domain
   11 - 135
   - Thioredoxin-like fold (IPR012336)
     - Thioredoxin domain (IPR013766)
       - Disulphide isomerase (IPR005788)
   136 - 474
   - Thioredoxin-like fold (IPR012336)
     - Thioredoxin domain (IPR013766)
       - Disulphide isomerase (IPR005788)

1 50 100 150 200 250 300 350 400 450 488

### Detailed signature matches

1. IPR005792
   Protein disulphide isomerase
   1. TIGR01130
      27 - 481
      UNKNOWN
      TIGR01130 (TIGR01130)
2. IPR005746
   Thioredoxin
   1. PR00421 (THIOREDOXIN)
      54 - 63
      PRINTS
      PR00421 (THIOREDOXIN)
      97 - 108
      PRINTS
      PR00421 (THIOREDOXIN)
      46 - 54
      PRINTS
      PR00421 (THIOREDOXIN)
3. IPR012336
   Thioredoxin-like fold
   1. PS51352 (THIOREDOXIN_2)
      354 - 474
      PROSITE profiles
      PS51352 (THIOREDOXIN_2)
      11 - 133
      PROSITE profiles
      PS51352 (THIOREDOXIN_2)
   2. G3DSA:3.40.30.10
      136 - 240
      GENE3D
      G3DSA:3.40.30.10 (G3DSA:3.40.30.10)
      364 - 472
      GENE3D
      G3DSA:3.40.30.10 (G3DSA:3.40.30.10)
      241 - 346
      GENE3D
      G3DSA:3.40.30.10 (G3DSA:3.40.30.10)
      24 - 135
      GENE3D
      G3DSA:3.40.30.10 (G3DSA:3.40.30.10)
   3. SSF52833 (Thioredox...)
      367 - 471
      SUPERFAMILY
      SSF52833 (Thioredoxin-like)
      23 - 134
      SUPERFAMILY
      SSF52833 (Thioredoxin-like)
      231 - 365
      SUPERFAMILY
      SSF52833 (Thioredoxin-like)
      138 - 235
      SUPERFAMILY
      SSF52833 (Thioredoxin-like)
4. IPR013766
   Thioredoxin domain
   1. PF00085 (Thioredoxin)
      28 - 130
      Pfam
      PF00085 (Thioredoxin)
      369 - 470
      Pfam
      PF00085 (Thioredoxin)
5. IPR005788
   Disulphide isomerase
   1. TIGR01126
      372 - 471
      UNKNOWN
      TIGR01126 (TIGR01126)
      31 - 131
      UNKNOWN
      TIGR01126 (TIGR01126)
6. IPR017937
   Thioredoxin, conserved site
   1. PS00194 (THIOREDOXIN_1)
      47 - 65
      PROSITE patterns
      PS00194 (THIOREDOXIN_1)
      389 - 407
      PROSITE patterns
      PS00194 (THIOREDOXIN_1)

no IPR
Unintegrated signatures

1. PF13848 (Thioredoxin_6)
   160 - 344
   Pfam
   PF13848 (Thioredoxin_6)
2. PTHR18929 (PROTEIN ...)
   1 - 479
   PANTHER
   PTHR18929 (PROTEIN DISULFIDE ISOMERASE)
3. PTHR18929:SF32 (SUB...)
   1 - 479
   PANTHER
   PTHR18929:SF32 (SUBFAMILY NOT NAMED)
4. SignalP-noTM
   1 - 18
   SignalP euk
   SignalP-noTM (SignalP-noTM)

### GO term prediction

#### Biological Process

GO:0006662 glycerol ether metabolic process
GO:0045454 cell redox homeostasis

#### Molecular Function

GO:0015035 protein disulfide oxidoreductase activity
GO:0016853 isomerase activity

#### Cellular Component

GO:0005783 endoplasmic reticulum