Protein

## EMLSAP00000001761

Length
1,788 amino acids

### Protein family membership

None predicted.

### Domains and repeats

1. Domain
   54 - 206
   - Nidogen, extracellular domain (IPR003886)
   382 - 420
   - Epidermal growth factor-like domain (IPR000742)
   421 - 462
   - Epidermal growth factor-like domain (IPR000742)
   463 - 502
   - Epidermal growth factor-like domain (IPR000742)
   506 - 612
   - Integrin alpha-2 (IPR013649)
   1,069 - 1,110
   - Epidermal growth factor-like domain (IPR000742)
   1,113 - 1,155
   - Epidermal growth factor-like domain (IPR000742)
   1,157 - 1,196
   - Epidermal growth factor-like domain (IPR000742)
   1,285 - 1,327
   - Epidermal growth factor-like domain (IPR000742)
   1,393 - 1,435
   - Epidermal growth factor-like domain (IPR000742)
   1,438 - 1,478
   - Epidermal growth factor-like domain (IPR000742)
   1,491 - 1,533
   - Epidermal growth factor-like domain (IPR000742)
2. Domain
   157 - 385
   - Green fluorescent protein (IPR009017)
     - G2 nidogen/fibulin G2F (IPR006605)
     - Green fluorescent protein-like (IPR023413)
   421 - 468
   - EGF-like calcium-binding domain (IPR001881)
   472 - 510
   - Green fluorescent protein-like (IPR023413)
   1,078 - 1,115
   - Green fluorescent protein-like (IPR023413)
   1,167 - 1,207
   - Green fluorescent protein-like (IPR023413)
   1,502 - 1,540
   - Green fluorescent protein-like (IPR023413)
   1,542 - 1,784
   - Six-bladed beta-propeller, TolB-like (IPR011042)
3. Domain
   384 - 507
   - Insulin-like growth factor binding protein, N-terminal (IPR009030)
4. Repeat
   1,565 - 1,744
   - LDLR class B repeat (IPR000033)
   1,748 - 1,788
   - LDLR class B repeat (IPR000033)

1 200 400 600 800 1000 1200 1400 1600 1788

### Detailed signature matches

1. IPR003886
   Nidogen, extracellular domain
   1. SM00539 (NIDO)
      54 - 206
      SMART
      SM00539 (NIDO)
   2. PF06119 (NIDO)
      119 - 202
      Pfam
      PF06119 (NIDO)
   3. PS51220 (NIDO)
      54 - 204
      PROSITE profiles
      PS51220 (NIDO)
2. IPR009017
   Green fluorescent protein
   1. SSF54511 (GFP-like)
      221 - 377
      SUPERFAMILY
      SSF54511 (GFP-like)
3. IPR006605
   G2 nidogen/fibulin G2F
   1. SM00682 (G2F)
      165 - 384
      SMART
      SM00682 (G2F)
   2. PS50993 (NIDOGEN_G2)
      157 - 385
      PROSITE profiles
      PS50993 (NIDOGEN_G2)
   3. PF07474 (G2F)
      221 - 343
      Pfam
      PF07474 (G2F)
4. IPR023413
   Green fluorescent protein-like
   1. G3DSA:2.40.15...
      1,167 - 1,207
      GENE3D
      G3DSA:2.40.155.10 (G3DSA:2.40.155.10)
      472 - 510
      GENE3D
      G3DSA:2.40.155.10 (G3DSA:2.40.155.10)
      1,502 - 1,540
      GENE3D
      G3DSA:2.40.155.10 (G3DSA:2.40.155.10)
      1,078 - 1,115
      GENE3D
      G3DSA:2.40.155.10 (G3DSA:2.40.155.10)
      221 - 377
      GENE3D
      G3DSA:2.40.155.10 (G3DSA:2.40.155.10)
5. IPR000742
   Epidermal growth factor-like domain
   1. PS50026 (EGF_3)
      1,491 - 1,533
      PROSITE profiles
      PS50026 (EGF_3)
      1,157 - 1,196
      PROSITE profiles
      PS50026 (EGF_3)
      1,438 - 1,478
      PROSITE profiles
      PS50026 (EGF_3)
      1,113 - 1,155
      PROSITE profiles
      PS50026 (EGF_3)
      382 - 420
      PROSITE profiles
      PS50026 (EGF_3)
      1,393 - 1,429
      PROSITE profiles
      PS50026 (EGF_3)
      1,069 - 1,108
      PROSITE profiles
      PS50026 (EGF_3)
      421 - 462
      PROSITE profiles
      PS50026 (EGF_3)
      463 - 502
      PROSITE profiles
      PS50026 (EGF_3)
      1,285 - 1,325
      PROSITE profiles
      PS50026 (EGF_3)
   2. SM00181 (EGF)
      424 - 462
      SMART
      SM00181 (EGF)
      466 - 502
      SMART
      SM00181 (EGF)
      1,160 - 1,196
      SMART
      SM00181 (EGF)
      1,494 - 1,533
      SMART
      SM00181 (EGF)
      1,288 - 1,327
      SMART
      SM00181 (EGF)
      385 - 420
      SMART
      SM00181 (EGF)
      1,396 - 1,435
      SMART
      SM00181 (EGF)
      1,116 - 1,155
      SMART
      SM00181 (EGF)
      1,441 - 1,478
      SMART
      SM00181 (EGF)
      1,072 - 1,110
      SMART
      SM00181 (EGF)
6. IPR009030
   Insulin-like growth factor binding protein, N-terminal
   1. SSF57184 (Growth fa...)
      384 - 507
      SUPERFAMILY
      SSF57184 (Growth factor receptor domain)
7. IPR001881
   EGF-like calcium-binding domain
   1. SM00179 (EGF_CA)
      421 - 468
      SMART
      SM00179 (EGF_CA)
   2. PF07645 (EGF_CA)
      421 - 457
      Pfam
      PF07645 (EGF_CA)
8. IPR013649
   Integrin alpha-2
   1. PF08441 (Integrin_a...)
      506 - 612
      Pfam
      PF08441 (Integrin_alpha2)
9. IPR011042
   Six-bladed beta-propeller, TolB-like
   1. G3DSA:2.120.1...
      1,542 - 1,784
      GENE3D
      G3DSA:2.120.10.30 (G3DSA:2.120.10.30)
10. IPR000033
    LDLR class B repeat
    1. PS51120 (LDLRB)
       1,766 - 1,788
       PROSITE profiles
       PS51120 (LDLRB)
       1,671 - 1,715
       PROSITE profiles
       PS51120 (LDLRB)
       1,628 - 1,670
       PROSITE profiles
       PS51120 (LDLRB)
       1,585 - 1,627
       PROSITE profiles
       PS51120 (LDLRB)
    2. PF00058 (Ldl_recept_b)
       1,675 - 1,711
       Pfam
       PF00058 (Ldl_recept_b)
       1,628 - 1,668
       Pfam
       PF00058 (Ldl_recept_b)
    3. SM00135 (LY)
       1,748 - 1,788
       SMART
       SM00135 (LY)
       1,565 - 1,607
       SMART
       SM00135 (LY)
       1,608 - 1,650
       SMART
       SM00135 (LY)
       1,651 - 1,695
       SMART
       SM00135 (LY)
       1,696 - 1,744
       SMART
       SM00135 (LY)
11. IPR013032
    EGF-like, conserved site
    1. PS01186 (EGF_2)
       1,096 - 1,109
       PROSITE patterns
       PS01186 (EGF_2)
       1,464 - 1,477
       PROSITE patterns
       PS01186 (EGF_2)
       1,182 - 1,195
       PROSITE patterns
       PS01186 (EGF_2)
       488 - 501
       PROSITE patterns
       PS01186 (EGF_2)
       1,260 - 1,275
       PROSITE patterns
       PS01186 (EGF_2)
       448 - 461
       PROSITE patterns
       PS01186 (EGF_2)
       406 - 419
       PROSITE patterns
       PS01186 (EGF_2)
       1,224 - 1,237
       PROSITE patterns
       PS01186 (EGF_2)
       1,141 - 1,154
       PROSITE patterns
       PS01186 (EGF_2)
12. IPR018097
    EGF-like calcium-binding, conserved site
    1. PS01187 (EGF_CA)
       421 - 448
       PROSITE patterns
       PS01187 (EGF_CA)
13. IPR000152
    EGF-type aspartate/asparagine hydroxylation site
    1. PS00010 (ASX_HYDROXYL)
       439 - 450
       PROSITE patterns
       PS00010 (ASX_HYDROXYL)

no IPR
Unintegrated signatures

1. G3DSA:2.10.25.10
   1,397 - 1,475
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
   384 - 458
   GENE3D
   G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
2. G3DSA:2.60.40...
   511 - 640
   GENE3D
   G3DSA:2.60.40.1530 (G3DSA:2.60.40.1530)
   977 - 1,043
   GENE3D
   G3DSA:2.60.40.1530 (G3DSA:2.60.40.1530)
3. PTHR10529 (LOW-DENS...)
   25 - 1,783
   PANTHER
   PTHR10529 (LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED)
4. PTHR10529:SF4 (NIDOGEN)
   25 - 1,783
   PANTHER
   PTHR10529:SF4 (NIDOGEN)
5. SSF57196 (EGF/Laminin)
   1,071 - 1,111
   SUPERFAMILY
   SSF57196 (EGF/Laminin)
6. SSF63825 (YWTD domain)
   1,567 - 1,784
   SUPERFAMILY
   SSF63825 (YWTD domain)
7. SSF69179 (Integrin ...)
   970 - 1,041
   SUPERFAMILY
   SSF69179 (Integrin domains)
   506 - 611
   SUPERFAMILY
   SSF69179 (Integrin domains)

### GO term prediction

#### Biological Process

GO:0007160 cell-matrix adhesion

#### Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

#### Cellular Component

None predicted.