Protein

## EMLSAP00000010618

Length
1,158 amino acids

### Protein family membership

- Deoxyhypusine hydroxylase (IPR027517)

### Domains and repeats

1. Domain
   8 - 295
   - Armadillo-type fold (IPR016024)
     - Armadillo-like helical (IPR011989)
   304 - 410
   - Calponin homology domain (IPR001715)
   440 - 502
   - Zinc finger, LIM-type (IPR001781)
   920 - 1,075
   - Domain of unknown function DUF3585 (IPR022735)
2. Repeat
   17 - 46
   - PBS lyase HEAT-like repeat (IPR004155)
   49 - 78
   - PBS lyase HEAT-like repeat (IPR004155)
   82 - 112
   - PBS lyase HEAT-like repeat (IPR004155)
   172 - 201
   - PBS lyase HEAT-like repeat (IPR004155)
   205 - 234
   - PBS lyase HEAT-like repeat (IPR004155)
   238 - 267
   - PBS lyase HEAT-like repeat (IPR004155)

1 200 400 600 800 1000 1158

### Detailed signature matches

1. IPR027517
   Deoxyhypusine hydroxylase
   1. MF_03101 (Deoxyhypu...)
      3 - 292
      HAMAP
      MF_03101 (Deoxyhypusine_hydroxylase)
2. IPR016024
   Armadillo-type fold
   1. SSF48371 (ARM repeat)
      14 - 295
      SUPERFAMILY
      SSF48371 (ARM repeat)
3. IPR011989
   Armadillo-like helical
   1. G3DSA:1.25.10.10
      8 - 113
      GENE3D
      G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
      161 - 281
      GENE3D
      G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
4. IPR001715
   Calponin homology domain
   1. PF00307 (CH)
      308 - 409
      Pfam
      PF00307 (CH)
   2. G3DSA:1.10.41...
      308 - 410
      GENE3D
      G3DSA:1.10.418.10 (G3DSA:1.10.418.10)
   3. SSF47576 (Calponin-...)
      307 - 409
      SUPERFAMILY
      SSF47576 (Calponin-homology domain, CH-domain)
   4. SM00033 (CH)
      306 - 405
      SMART
      SM00033 (CH)
   5. PS50021 (CH)
      304 - 407
      PROSITE profiles
      PS50021 (CH)
5. IPR001781
   Zinc finger, LIM-type
   1. SM00132 (LIM)
      441 - 495
      SMART
      SM00132 (LIM)
   2. PS50023 (LIM_DOMAIN_2)
      440 - 502
      PROSITE profiles
      PS50023 (LIM_DOMAIN_2)
   3. G3DSA:2.10.11...
      441 - 497
      GENE3D
      G3DSA:2.10.110.10 (G3DSA:2.10.110.10)
6. IPR022735
   Domain of unknown function DUF3585
   1. PF12130 (DUF3585)
      920 - 1,075
      Pfam
      PF12130 (DUF3585)
7. IPR004155
   PBS lyase HEAT-like repeat
   1. SM00567 (EZ_HEAT)
      172 - 201
      SMART
      SM00567 (EZ_HEAT)
      17 - 46
      SMART
      SM00567 (EZ_HEAT)
      82 - 112
      SMART
      SM00567 (EZ_HEAT)
      49 - 78
      SMART
      SM00567 (EZ_HEAT)
      205 - 234
      SMART
      SM00567 (EZ_HEAT)
      238 - 267
      SMART
      SM00567 (EZ_HEAT)

no IPR
Unintegrated signatures

1. Coil
   1,008 - 1,029
   COILS
   Coil (Coil)
   655 - 676
   COILS
   Coil (Coil)
2. PF13646 (HEAT_2)
   203 - 280
   Pfam
   PF13646 (HEAT_2)
   41 - 113
   Pfam
   PF13646 (HEAT_2)
3. PTHR12697 (PBS LYAS...)
   2 - 297
   PANTHER
   PTHR12697 (PBS LYASE HEAT-LIKE PROTEIN)

### GO term prediction

#### Biological Process

GO:0008612 peptidyl-lysine modification to hypusine

#### Molecular Function

GO:0005488 binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0019135 deoxyhypusine monooxygenase activity

#### Cellular Component

None predicted.