EMLSAG00000000022, EMLSAG00000000022-682788 (gene) Lepeophtheirus salmonis

Overview
NameEMLSAG00000000022
Unique NameEMLSAG00000000022-682788
Typegene
OrganismLepeophtheirus salmonis (salmon louse)
Associated RNAi Experiments

Nothing found

Homology
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:Rims2 "regulating synaptic membrane exocytosis 2" species:10090 "Mus musculus" [GO:0005515 "protein binding" evidence=IPI] [GO:0005622 "intracellular" evidence=IDA] [GO:0005623 "cell" evidence=IGI] [GO:0006810 "transport" evidence=IEA] [GO:0006836 "neurotransmitter transport" evidence=IEA] [GO:0006886 "intracellular protein transport" evidence=IEA] [GO:0006887 "exocytosis" evidence=IEA] [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0017156 "calcium ion-dependent exocytosis" evidence=IDA] [GO:0017157 "regulation of exocytosis" evidence=IMP] [GO:0019904 "protein domain specific binding" evidence=ISO] [GO:0019933 "cAMP-mediated signaling" evidence=IDA] [GO:0030054 "cell junction" evidence=IEA] [GO:0030073 "insulin secretion" evidence=IMP;IDA] [GO:0042391 "regulation of membrane potential" evidence=IDA] [GO:0043005 "neuron projection" evidence=IEA] [GO:0043234 "protein complex" evidence=ISO] [GO:0044325 "ion channel binding" evidence=IDA] [GO:0045202 "synapse" evidence=ISO] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0046982 "protein heterodimerization activity" evidence=ISO] [GO:0048791 "calcium ion-dependent exocytosis of neurotransmitter" evidence=IGI] [GO:2000300 "regulation of synaptic vesicle exocytosis" evidence=ISO] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 Pfam:PF02318 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 MGI:MGI:2152972 GO:GO:0006886 GO:GO:0046872 GO:GO:0019933 GO:GO:0030054 GO:GO:0043005 GO:GO:0045202 GO:GO:0042391 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 GO:GO:0017156 SUPFAM:SSF50156 GO:GO:0006836 GO:GO:0044325 GO:GO:0030073 GO:GO:0048791 GO:GO:0017157 eggNOG:NOG286957 HOGENOM:HOG000082403 HOVERGEN:HBG058147 OrthoDB:EOG7BGHJV CTD:9699 KO:K15297 EMBL:AB021131 EMBL:AK032619 EMBL:AK083172 RefSeq:NP_001243313.1 RefSeq:NP_444501.1 UniGene:Mm.309296 ProteinModelPortal:Q9EQZ7 SMR:Q9EQZ7 BioGrid:228026 PhosphoSite:Q9EQZ7 PaxDb:Q9EQZ7 PRIDE:Q9EQZ7 Ensembl:ENSMUST00000082054 GeneID:116838 KEGG:mmu:116838 UCSC:uc007vod.2 UCSC:uc007voh.2 GeneTree:ENSGT00550000074588 NextBio:369190 PRO:PR:Q9EQZ7 ArrayExpress:Q9EQZ7 Bgee:Q9EQZ7 CleanEx:MM_RIMS2 Genevestigator:Q9EQZ7 Uniprot:Q9EQZ7)

HSP 1 Score: 68.5514 bits (166), Expect = 5.425e-12
Identity = 46/74 (62.16%), Postives = 52/74 (70.27%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK-DSQN 199
            RNDSLSSDQSE VRPPPP+PHK K        +   + LSSSEEEL STP+  TSC+  E ESES+SEK DSQ 
Sbjct:  519 RNDSLSSDQSESVRPPPPRPHKSKK-----GGKMRQVSLSSSEEELASTPEY-TSCDDVELESESVSEKGDSQK 586
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:Rims2 "Regulating synaptic membrane exocytosis protein 2" species:10116 "Rattus norvegicus" [GO:0006886 "intracellular protein transport" evidence=IEA] [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 Pfam:PF02318 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 GO:GO:0006886 GO:GO:0046872 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 SUPFAM:SSF50156 GeneTree:ENSGT00550000074588 EMBL:AABR06050516 EMBL:AABR06050517 EMBL:AABR06050518 EMBL:AABR06050519 EMBL:AABR06050520 EMBL:AABR06050521 EMBL:AABR06050522 EMBL:AABR06050523 EMBL:AABR06050524 EMBL:AABR06050525 Ensembl:ENSRNOT00000050753 NextBio:35575765 Uniprot:F1LNC5)

HSP 1 Score: 66.6254 bits (161), Expect = 1.976e-11
Identity = 43/69 (62.32%), Postives = 49/69 (71.01%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRPPPP+PHK K        +   + LSSSEEEL STP+  TSC+  E ESES+SEK
Sbjct:  479 RNDSLSSDQSESVRPPPPRPHKSKK-----GGKMRQVSLSSSEEELASTPEY-TSCDDVEIESESVSEK 541
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:Rims2 "Regulating synaptic membrane exocytosis protein 2" species:10116 "Rattus norvegicus" [GO:0006886 "intracellular protein transport" evidence=IEA] [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 Pfam:PF02318 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 GO:GO:0006886 GO:GO:0046872 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 SUPFAM:SSF50156 GeneTree:ENSGT00550000074588 EMBL:AABR06050516 EMBL:AABR06050517 EMBL:AABR06050518 EMBL:AABR06050519 EMBL:AABR06050520 EMBL:AABR06050521 EMBL:AABR06050522 EMBL:AABR06050523 EMBL:AABR06050524 EMBL:AABR06050525 Ensembl:ENSRNOT00000041618 NextBio:35574092 ArrayExpress:D4ABU5 Uniprot:D4ABU5)

HSP 1 Score: 66.6254 bits (161), Expect = 2.007e-11
Identity = 43/69 (62.32%), Postives = 49/69 (71.01%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRPPPP+PHK K        +   + LSSSEEEL STP+  TSC+  E ESES+SEK
Sbjct:  479 RNDSLSSDQSESVRPPPPRPHKSKK-----GGKMRQVSLSSSEEELASTPEY-TSCDDVEIESESVSEK 541
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:Rims2 "Regulating synaptic membrane exocytosis protein 2" species:10116 "Rattus norvegicus" [GO:0006886 "intracellular protein transport" evidence=IEA] [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0017156 "calcium ion-dependent exocytosis" evidence=IEA] [GO:0017157 "regulation of exocytosis" evidence=IEA] [GO:0019933 "cAMP-mediated signaling" evidence=IEA] [GO:0030054 "cell junction" evidence=IEA] [GO:0030073 "insulin secretion" evidence=IEA] [GO:0042391 "regulation of membrane potential" evidence=IEA] [GO:0042734 "presynaptic membrane" evidence=IEA] [GO:0044325 "ion channel binding" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0048791 "calcium ion-dependent exocytosis of neurotransmitter" evidence=IEA] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 Pfam:PF02318 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 RGD:620001 GO:GO:0006886 GO:GO:0046872 GO:GO:0019933 GO:GO:0030054 GO:GO:0042734 GO:GO:0042391 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 GO:GO:0017156 SUPFAM:SSF50156 GO:GO:0030073 GO:GO:0048791 GO:GO:0017157 eggNOG:NOG286957 HOVERGEN:HBG058147 OrthoDB:EOG7BGHJV CTD:9699 KO:K15297 GeneTree:ENSGT00550000074588 EMBL:AF199322 EMBL:AF199323 EMBL:AF199324 EMBL:AF199325 EMBL:AF199326 EMBL:AF199327 EMBL:AF199328 EMBL:AF199329 EMBL:AF199330 EMBL:AF199331 EMBL:AF199332 EMBL:AF199335 EMBL:AF548738 RefSeq:NP_446397.1 RefSeq:NP_665888.1 UniGene:Rn.161948 PDB:2A20 PDB:2BWQ PDB:2CJS PDBsum:2A20 PDBsum:2BWQ PDBsum:2CJS ProteinModelPortal:Q9JIS1 SMR:Q9JIS1 DIP:DIP-29192N IntAct:Q9JIS1 MINT:MINT-270417 PhosphoSite:Q9JIS1 PaxDb:Q9JIS1 PRIDE:Q9JIS1 Ensembl:ENSRNOT00000006393 GeneID:116839 KEGG:rno:116839 InParanoid:Q9JIS1 OMA:SSARMKN EvolutionaryTrace:Q9JIS1 NextBio:619731 Genevestigator:Q9JIS1 Uniprot:Q9JIS1)

HSP 1 Score: 65.855 bits (159), Expect = 3.438e-11
Identity = 42/69 (60.87%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRPPPP+PHK K        +   + LSSSEEEL STP+  TSC+  E ESES+ EK
Sbjct:  479 RNDSLSSDQSESVRPPPPRPHKSKK-----GGKMRQVSLSSSEEELASTPEY-TSCDDVEIESESVGEK 541
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:Rims2 "regulating synaptic membrane exocytosis 2" species:10116 "Rattus norvegicus" [GO:0005515 "protein binding" evidence=IPI] [GO:0005622 "intracellular" evidence=ISO] [GO:0005623 "cell" evidence=ISO] [GO:0006887 "exocytosis" evidence=TAS] [GO:0017156 "calcium ion-dependent exocytosis" evidence=ISO] [GO:0017157 "regulation of exocytosis" evidence=ISO] [GO:0019904 "protein domain specific binding" evidence=IDA] [GO:0019933 "cAMP-mediated signaling" evidence=ISO] [GO:0030073 "insulin secretion" evidence=ISO] [GO:0042391 "regulation of membrane potential" evidence=ISO] [GO:0043234 "protein complex" evidence=IDA] [GO:0044325 "ion channel binding" evidence=ISO] [GO:0045202 "synapse" evidence=IDA] [GO:0046982 "protein heterodimerization activity" evidence=IDA] [GO:0048791 "calcium ion-dependent exocytosis of neurotransmitter" evidence=ISO] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 Pfam:PF02318 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 RGD:620001 GO:GO:0006886 GO:GO:0046872 GO:GO:0019933 GO:GO:0030054 GO:GO:0042734 GO:GO:0042391 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 GO:GO:0017156 SUPFAM:SSF50156 GO:GO:0030073 GO:GO:0048791 GO:GO:0017157 eggNOG:NOG286957 HOVERGEN:HBG058147 OrthoDB:EOG7BGHJV CTD:9699 KO:K15297 GeneTree:ENSGT00550000074588 EMBL:AF199322 EMBL:AF199323 EMBL:AF199324 EMBL:AF199325 EMBL:AF199326 EMBL:AF199327 EMBL:AF199328 EMBL:AF199329 EMBL:AF199330 EMBL:AF199331 EMBL:AF199332 EMBL:AF199335 EMBL:AF548738 RefSeq:NP_446397.1 RefSeq:NP_665888.1 UniGene:Rn.161948 PDB:2A20 PDB:2BWQ PDB:2CJS PDBsum:2A20 PDBsum:2BWQ PDBsum:2CJS ProteinModelPortal:Q9JIS1 SMR:Q9JIS1 DIP:DIP-29192N IntAct:Q9JIS1 MINT:MINT-270417 PhosphoSite:Q9JIS1 PaxDb:Q9JIS1 PRIDE:Q9JIS1 Ensembl:ENSRNOT00000006393 GeneID:116839 KEGG:rno:116839 InParanoid:Q9JIS1 OMA:SSARMKN EvolutionaryTrace:Q9JIS1 NextBio:619731 Genevestigator:Q9JIS1 Uniprot:Q9JIS1)

HSP 1 Score: 65.855 bits (159), Expect = 3.438e-11
Identity = 42/69 (60.87%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRPPPP+PHK K        +   + LSSSEEEL STP+  TSC+  E ESES+ EK
Sbjct:  479 RNDSLSSDQSESVRPPPPRPHKSKK-----GGKMRQVSLSSSEEELASTPEY-TSCDDVEIESESVGEK 541
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:RIMS1 "Regulating synaptic membrane exocytosis protein 1" species:9606 "Homo sapiens" [GO:0006886 "intracellular protein transport" evidence=IEA] [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 GO:GO:0006886 GO:GO:0046872 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 SUPFAM:SSF50156 EMBL:AL160405 EMBL:AL590011 EMBL:AL034373 EMBL:AL390056 EMBL:AL445256 EMBL:AL035633 HGNC:HGNC:17282 ChiTaRS:RIMS1 ProteinModelPortal:E7ENC2 SMR:E7ENC2 Ensembl:ENST00000348717 UCSC:uc011dyb.2 NextBio:35499584 ArrayExpress:E7ENC2 Bgee:E7ENC2 Uniprot:E7ENC2)

HSP 1 Score: 62.3882 bits (150), Expect = 4.684e-10
Identity = 42/69 (60.87%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRP PPKPH+ K        +K  + +SSSEEE  STP+  TSCE  E ESES+SEK
Sbjct:  497 RNDSLSSDQSESVRPSPPKPHRSKR-----GGKKRQMSVSSSEEEGVSTPEY-TSCEDVELESESVSEK 559
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:Gga.43738 "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0006461 "protein complex assembly" evidence=IEA] [GO:0006886 "intracellular protein transport" evidence=IEA] [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0042391 "regulation of membrane potential" evidence=IEA] [GO:0044325 "ion channel binding" evidence=IEA] [GO:0045202 "synapse" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0048169 "regulation of long-term neuronal synaptic plasticity" evidence=IEA] [GO:0048791 "calcium ion-dependent exocytosis of neurotransmitter" evidence=IEA] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 Pfam:PF02318 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 GO:GO:0006886 GO:GO:0046872 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 SUPFAM:SSF50156 OrthoDB:EOG7BGHJV TreeFam:TF321703 GeneTree:ENSGT00550000074588 EMBL:AADN03003516 EMBL:AADN03003682 Ensembl:ENSGALT00000025694 Uniprot:F1P5P9)

HSP 1 Score: 62.3882 bits (150), Expect = 4.997e-10
Identity = 42/69 (60.87%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRP PPKPH+ K        +K  + +SSSEEE  STP+  TSCE  E ESES+SEK
Sbjct:  468 RNDSLSSDQSESVRPSPPKPHRAKR-----GGKKRQMSVSSSEEEGASTPEY-TSCEDVEIESESVSEK 530
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:RIMS1 "Regulating synaptic membrane exocytosis protein 1" species:9606 "Homo sapiens" [GO:0005083 "small GTPase regulator activity" evidence=TAS] [GO:0005515 "protein binding" evidence=IPI] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0006461 "protein complex assembly" evidence=IDA] [GO:0006886 "intracellular protein transport" evidence=IEA] [GO:0007268 "synaptic transmission" evidence=TAS] [GO:0007269 "neurotransmitter secretion" evidence=TAS] [GO:0007601 "visual perception" evidence=IEA] [GO:0014047 "glutamate secretion" evidence=TAS] [GO:0016079 "synaptic vesicle exocytosis" evidence=TAS] [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0017156 "calcium ion-dependent exocytosis" evidence=TAS] [GO:0030054 "cell junction" evidence=IEA] [GO:0042391 "regulation of membrane potential" evidence=IEA] [GO:0042734 "presynaptic membrane" evidence=ISS;NAS] [GO:0044325 "ion channel binding" evidence=IEA] [GO:0044822 "poly(A) RNA binding" evidence=IDA] [GO:0045055 "regulated secretory pathway" evidence=NAS] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0046903 "secretion" evidence=NAS] [GO:0048169 "regulation of long-term neuronal synaptic plasticity" evidence=IEA] [GO:0048791 "calcium ion-dependent exocytosis of neurotransmitter" evidence=IEA] [GO:0050790 "regulation of catalytic activity" evidence=TAS] [GO:0050896 "response to stimulus" evidence=IEA] [GO:0061025 "membrane fusion" evidence=NAS] Reactome:REACT_13685 Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 Pfam:PF02318 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 GO:GO:0006886 GO:GO:0006461 GO:GO:0046872 GO:GO:0030054 GO:GO:0007601 GO:GO:0042734 Orphanet:1872 GO:GO:0050896 GO:GO:0042391 SUPFAM:SSF49562 GO:GO:0061025 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 GO:GO:0017156 SUPFAM:SSF50156 GO:GO:0048169 GO:GO:0014047 GO:GO:0016079 GO:GO:0005083 GO:GO:0048791 GO:GO:0045055 EMBL:AY190519 EMBL:AB045726 EMBL:AB051866 EMBL:AB002338 EMBL:AK296303 EMBL:AK294868 EMBL:AK295001 EMBL:AK300853 EMBL:AK309185 EMBL:AL160405 EMBL:AL590011 EMBL:AL034373 EMBL:AL390056 EMBL:AL445256 EMBL:AL035633 EMBL:BC151853 EMBL:BC152435 EMBL:AF263305 EMBL:AF263306 EMBL:AF263307 EMBL:AF263308 EMBL:AF263309 EMBL:AF263310 RefSeq:NP_001161879.1 RefSeq:NP_001161880.1 RefSeq:NP_001161881.1 RefSeq:NP_001161882.1 RefSeq:NP_001161883.1 RefSeq:NP_055804.2 RefSeq:XP_005248749.1 UniGene:Hs.485729 PDB:2CSS PDBsum:2CSS ProteinModelPortal:Q86UR5 SMR:Q86UR5 BioGrid:116646 IntAct:Q86UR5 MINT:MINT-2808819 PhosphoSite:Q86UR5 DMDM:34395763 PaxDb:Q86UR5 PRIDE:Q86UR5 Ensembl:ENST00000264839 Ensembl:ENST00000370420 Ensembl:ENST00000401910 Ensembl:ENST00000414192 Ensembl:ENST00000425662 Ensembl:ENST00000491071 Ensembl:ENST00000517827 Ensembl:ENST00000517960 Ensembl:ENST00000518273 Ensembl:ENST00000520567 Ensembl:ENST00000521978 Ensembl:ENST00000522291 Ensembl:ENST00000523963 GeneID:22999 KEGG:hsa:22999 UCSC:uc003pga.4 UCSC:uc003pgb.4 UCSC:uc003pgc.3 UCSC:uc010kas.1 CTD:22999 GeneCards:GC06P072653 HGNC:HGNC:17282 HPA:HPA039297 MIM:603649 MIM:606629 neXtProt:NX_Q86UR5 PharmGKB:PA38220 eggNOG:NOG286957 HOGENOM:HOG000082403 HOVERGEN:HBG058147 InParanoid:Q86UR5 KO:K15291 OMA:ERKKTPG OrthoDB:EOG7BGHJV TreeFam:TF321703 ChiTaRS:RIMS1 EvolutionaryTrace:Q86UR5 GeneWiki:RIMS1 GenomeRNAi:22999 NextBio:43896 PRO:PR:Q86UR5 ArrayExpress:Q86UR5 Bgee:Q86UR5 Genevestigator:Q86UR5 Uniprot:Q86UR5)

HSP 1 Score: 62.003 bits (149), Expect = 5.549e-10
Identity = 42/69 (60.87%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRP PPKPH+ K        +K  + +SSSEEE  STP+  TSCE  E ESES+SEK
Sbjct:  497 RNDSLSSDQSESVRPSPPKPHRSKR-----GGKKRQMSVSSSEEEGVSTPEY-TSCEDVELESESVSEK 559
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:rims1a "regulating synaptic membrane exocytosis 1a" species:7955 "Danio rerio" [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0006886 "intracellular protein transport" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 InterPro:IPR010911 Pfam:PF00168 PROSITE:PS50004 PROSITE:PS50106 PROSITE:PS50916 SMART:SM00228 SMART:SM00239 ZFIN:ZDB-GENE-090312-135 GO:GO:0006886 GO:GO:0046872 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR017455 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 PROSITE:PS50178 SUPFAM:SSF50156 TreeFam:TF321703 GeneTree:ENSGT00550000074588 OMA:HLIFNDS EMBL:CR354543 EMBL:CR356236 Ensembl:ENSDART00000112553 Uniprot:F1RCJ3)

HSP 1 Score: 61.6178 bits (148), Expect = 7.272e-10
Identity = 38/67 (56.72%), Postives = 47/67 (70.15%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCEEFESESISEK 195
            RNDSLSSDQSE +RPPPP+P+K K         K  + +SSSEEE  STP+  TSCE+ E ES+SE+
Sbjct:  469 RNDSLSSDQSESLRPPPPRPYKSKR-----GGNKRQMSVSSSEEEAGSTPE-YTSCEDVEIESVSER 529
[Close]
BLAST of EMLSAG00000000022 vs. GO
Match: - (symbol:RIMS1 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0006461 "protein complex assembly" evidence=IEA] [GO:0042391 "regulation of membrane potential" evidence=IEA] [GO:0044325 "ion channel binding" evidence=IEA] [GO:0045202 "synapse" evidence=IEA] [GO:0048169 "regulation of long-term neuronal synaptic plasticity" evidence=IEA] [GO:0048791 "calcium ion-dependent exocytosis of neurotransmitter" evidence=IEA] Pfam:PF00595 InterPro:IPR000008 InterPro:IPR001478 Pfam:PF00168 PROSITE:PS50004 PROSITE:PS50106 SMART:SM00228 SMART:SM00239 GO:GO:0006461 GO:GO:0045202 GO:GO:0042391 SUPFAM:SSF49562 Gene3D:3.30.40.10 InterPro:IPR013083 SUPFAM:SSF50156 GO:GO:0048169 GO:GO:0048791 OMA:ERKKTPG OrthoDB:EOG7BGHJV TreeFam:TF321703 GeneTree:ENSGT00550000074588 EMBL:DAAA02025209 EMBL:DAAA02025210 EMBL:DAAA02025211 EMBL:DAAA02025212 EMBL:DAAA02025213 EMBL:DAAA02025214 Ensembl:ENSBTAT00000061208 Uniprot:F1N7B7)

HSP 1 Score: 61.6178 bits (148), Expect = 8.952e-10
Identity = 41/69 (59.42%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRP PPKPH+ K        ++  + +SSSEEE  STP+  TSCE  E ESES+SEK
Sbjct:  336 RNDSLSSDQSESVRPSPPKPHRAKR-----GGKRRQMSVSSSEEEGVSTPEY-TSCEDVELESESVSEK 398
[Close]
BLAST of EMLSAG00000000022 vs. C. finmarchicus
Match: gi|592749621|gb|GAXK01204792.1| (TSA: Calanus finmarchicus comp540019_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 36.5798 bits (83), Expect = 4.738e-2
Identity = 35/74 (47.30%), Postives = 42/74 (56.76%), Query Frame = 0 
Query:   74 NIPRHHSRD----LYPRVLVSEGESRDQCTPLFDPETG-QPSL---XXXXXXXXXXMMGLHYRRNDSLSSDQSE 139
            + P  H RD    LYPRVLVS+ E+RDQ   + + E   Q SL   N     + RR M   + RNDSLSSDQSE
Sbjct: 5231 SAPEDHGRDGPYNLYPRVLVSDQEARDQFPVMSETEMKIQKSLLDPNDARGVSNRRKMDSSF-RNDSLSSDQSE 5449
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BLAST of EMLSAG00000000022 vs. L. salmonis peptides
Match: EMLSAP00000000022 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1004:92038:93364:-1 gene:EMLSAG00000000022 transcript:EMLSAT00000000022 description:"snap-LSalAtl2s1004-processed-gene-0.16")

HSP 1 Score: 407.142 bits (1045), Expect = 1.018e-145
Identity = 201/201 (100.00%), Postives = 201/201 (100.00%), Query Frame = 0 
Query:    1 MPDPSIDNIISSNPPPHHFPYTPRQAPPFTHQRPFYPRFPRGQQLSRQRSLEGGFPSSASSSASSTAGGAPEDNIPRHHSRDLYPRVLVSEGESRDQCTPLFDPETGQPSLNGGGNQNRRRMMGLHYRRNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCEEFESESISEKDSQNMN 201
            MPDPSIDNIISSNPPPHHFPYTPRQAPPFTHQRPFYPRFPRGQQLSRQRSLEGGFPSSASSSASSTAGGAPEDNIPRHHSRDLYPRVLVSEGESRDQCTPLFDPETGQPSLNGGGNQNRRRMMGLHYRRNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCEEFESESISEKDSQNMN
Sbjct:    1 MPDPSIDNIISSNPPPHHFPYTPRQAPPFTHQRPFYPRFPRGQQLSRQRSLEGGFPSSASSSASSTAGGAPEDNIPRHHSRDLYPRVLVSEGESRDQCTPLFDPETGQPSLNGGGNQNRRRMMGLHYRRNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCEEFESESISEKDSQNMN 201
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BLAST of EMLSAG00000000022 vs. SwissProt
Match: gi|34395823|sp|Q9EQZ7.1|RIMS2_MOUSE (RecName: Full=Regulating synaptic membrane exocytosis protein 2; AltName: Full=Rab-3-interacting molecule 2; Short=RIM 2; AltName: Full=Rab-3-interacting protein 2)

HSP 1 Score: 68.5514 bits (166), Expect = 2.083e-12
Identity = 46/74 (62.16%), Postives = 52/74 (70.27%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK-DSQN 199
            RNDSLSSDQSE VRPPPP+PHK K        +   + LSSSEEEL STP+  TSC+  E ESES+SEK DSQ 
Sbjct:  519 RNDSLSSDQSESVRPPPPRPHKSKK-----GGKMRQVSLSSSEEELASTPEY-TSCDDVELESESVSEKGDSQK 586
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BLAST of EMLSAG00000000022 vs. SwissProt
Match: gi|34395746|sp|Q9JIS1.1|RIMS2_RAT (RecName: Full=Regulating synaptic membrane exocytosis protein 2; AltName: Full=Rab-3-interacting molecule 2; Short=RIM 2)

HSP 1 Score: 65.855 bits (159), Expect = 1.532e-11
Identity = 42/69 (60.87%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRPPPP+PHK K        +   + LSSSEEEL STP+  TSC+  E ESES+ EK
Sbjct:  479 RNDSLSSDQSESVRPPPPRPHKSKK-----GGKMRQVSLSSSEEELASTPEY-TSCDDVEIESESVGEK 541
[Close]
BLAST of EMLSAG00000000022 vs. SwissProt
Match: gi|34395763|sp|Q86UR5.1|RIMS1_HUMAN (RecName: Full=Regulating synaptic membrane exocytosis protein 1; AltName: Full=Rab-3-interacting molecule 1; Short=RIM 1; AltName: Full=Rab-3-interacting protein 2)

HSP 1 Score: 62.003 bits (149), Expect = 3.080e-10
Identity = 42/69 (60.87%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRP PPKPH+ K        +K  + +SSSEEE  STP+  TSCE  E ESES+SEK
Sbjct:  497 RNDSLSSDQSESVRPSPPKPHRSKR-----GGKKRQMSVSSSEEEGVSTPEY-TSCEDVELESESVSEK 559
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BLAST of EMLSAG00000000022 vs. SwissProt
Match: gi|34395745|sp|Q9JIR4.1|RIMS1_RAT (RecName: Full=Regulating synaptic membrane exocytosis protein 1; AltName: Full=Rab-3-interacting molecule 1; Short=RIM 1)

HSP 1 Score: 60.077 bits (144), Expect = 1.650e-9
Identity = 41/69 (59.42%), Postives = 48/69 (69.57%), Query Frame = 0 
Query:  129 RNDSLSSDQSECVRPPPPKPHKRKTHLHHPHSEKGLILLSSSEEELQSTPDCTTSCE--EFESESISEK 195
            RNDSLSSDQSE VRP PPKPH+ K        ++  + +SSSEEE  STP+  TSCE  E ESES+SEK
Sbjct:  511 RNDSLSSDQSESVRPSPPKPHRPKR-----GGKRRQMSVSSSEEEGVSTPE-YTSCEDVELESESVSEK 573
The following BLAST results are available for this feature:
BLAST of EMLSAG00000000022 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO)
Total hits: 20
Match NameE-valueIdentityDescription
-5.425e-1262.16symbol:Rims2 "regulating synaptic membrane exocyto... [more]
-1.976e-1162.32symbol:Rims2 "Regulating synaptic membrane exocyto... [more]
-2.007e-1162.32symbol:Rims2 "Regulating synaptic membrane exocyto... [more]
-3.438e-1160.87symbol:Rims2 "Regulating synaptic membrane exocyto... [more]
-3.438e-1160.87symbol:Rims2 "regulating synaptic membrane exocyto... [more]
-4.684e-1060.87symbol:RIMS1 "Regulating synaptic membrane exocyto... [more]
-4.997e-1060.87symbol:Gga.43738 "Uncharacterized protein" species... [more]
-5.549e-1060.87symbol:RIMS1 "Regulating synaptic membrane exocyto... [more]
-7.272e-1056.72symbol:rims1a "regulating synaptic membrane exocyt... [more]
-8.952e-1059.42symbol:RIMS1 "Uncharacterized protein" species:991... [more]

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BLAST of EMLSAG00000000022 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA)
Total hits: 1
Match NameE-valueIdentityDescription
gi|592749621|gb|GAXK01204792.1|4.738e-247.30TSA: Calanus finmarchicus comp540019_c0_seq1 trans... [more]
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BLAST of EMLSAG00000000022 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self)
Total hits: 1
Match NameE-valueIdentityDescription
EMLSAP000000000221.018e-145100.00pep:novel supercontig:LSalAtl2s:LSalAtl2s1004:9203... [more]
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BLAST of EMLSAG00000000022 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt)
Total hits: 4
Match NameE-valueIdentityDescription
gi|34395823|sp|Q9EQZ7.1|RIMS2_MOUSE2.083e-1262.16RecName: Full=Regulating synaptic membrane exocyto... [more]
gi|34395746|sp|Q9JIS1.1|RIMS2_RAT1.532e-1160.87RecName: Full=Regulating synaptic membrane exocyto... [more]
gi|34395763|sp|Q86UR5.1|RIMS1_HUMAN3.080e-1060.87RecName: Full=Regulating synaptic membrane exocyto... [more]
gi|34395745|sp|Q9JIR4.1|RIMS1_RAT1.650e-959.42RecName: Full=Regulating synaptic membrane exocyto... [more]
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BLAST of EMLSAG00000000022 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EMLSAG00000000022 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017))
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EMLSAG00000000022 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins)
Total hits: 0
Match NameE-valueIdentityDescription
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Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
LSalAtl2s1004supercontigLSalAtl2s1004:92038..93364 -
Analyses
This gene is derived from or has results from the following analyses
Analysis NameDate Performed
ensembl2013-09-26 .965016
Blast vs. GO2014-04-02
TblastN vs C. finmarchicus TSA2014-05-09
Blastp vs. self2014-05-10
Blastp vs. SwissProt2017-02-10
Blastp vs. Selected Arthropods2017-02-20
Blastp vs. NR (2/2017)2017-02-20
Blastp vs. Tigriopus kingsejongensis proteins2018-04-18
Properties
Property NameValue
Logic nameensemblgenomes
Descriptionsnap-LSalAtl2s1004-processed-gene-0.16
Biotypeprotein_coding
EvidenceIEA
NoteRegulating synaptic membrane exocytosis protein 2
Cross References
External references for this gene
DatabaseAccession
Ensembl Metazoa (gene)EMLSAG00000000022 (primary cross-reference)
Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameSpeciesType
EMLSAT00000000022EMLSAT00000000022-695869Lepeophtheirus salmonismRNA


Sequences
The following sequences are available for this feature:

gene from alignment at LSalAtl2s1004:92038..93364-

Legend: mRNA
Hold the cursor over a type above to highlight its positions in the sequence below.
>EMLSAG00000000022-682788 ID=EMLSAG00000000022-682788|Name=EMLSAG00000000022|organism=Lepeophtheirus salmonis|type=gene|length=1327bp|location=Sequence derived from alignment at LSalAtl2s1004:92038..93364- (Lepeophtheirus salmonis)
ATGCCGGATCCCAGCATCGACAATATCATATCATCAAACCCTCCTCCTCA
CCATTTTCCATATACACCTCGTCAAGCACCGCCATTTACTCATCAACGAC
CATTTTATCCAAGGTAAGAAAATGTACTTAATCCACAATAGCGTTTTTTT
CCGGGATCCCGTTGTCTCAGAATTTACACCAATGGGAAATCATTCATTTC
ATTATTTCATAATATAGGCTTAATTTAAACTAAAAATTAAGCCATAAATA
TAAACATATGTCCGGTAATTGATTTGTAAACTGTTCCATGACGTCACATA
TGTTTCATATTTATATTTATTTAGAGTGTTTTTGAAGTGGTATGAAATGT
TGCATTTTAAATATCTATTATTTTTATCAAATGAATTACAGTGATACGGT
AGTTGACTTTTAGCCGAGACTCGGTAAAGAAATGAGAACCCGCGTGCTCA
CTAATTCTATTGTATTGACTAAATTAACTAAGATATCTTTAATTCTCAAC
AGATTCCCTCGAGGACAACAGCTATCGAGACAAAGATCTCTTGAGGGAGG
ATTTCCATCATCAGCCTCATCTTCTGCTTCGTCCACAGCTGGAGGTGGTA
TSCATCATCTKCCATCATCAATTATRCCARCCCCAKCAGCCTCTATCTCC
TCTAATAGAGGAGGTACGCCACGCCGTTTAAGTGAGGGAGAACCACCTCG
WTTGTTTCGRTATCCATATCAGCATYGAGGCGGCAGCCGCATGCCTCCRC
CAAGTTATCGTAMGCGCCATCCTCCATCATCTTGGGGTCGAGAATCTCTC
TCAGCCCCTGAAGACAACATTCCGCGTCATCATAGTCGTGATCTGTATCC
TCGAGTTCTTGTCTCAGAAGGAGAATCCAGGGATCAATGTACTCCTTTAT
TTGATCCCGAAACGGGTCAACCATCACTCAATGGTGGTGGAAATCAAAAT
CGGCGTCGGATGATGGGACTTCATTACCGAAGAAATGACTCACTTTCATC
GGATCAAAGTGAGTGTGTCCGACCACCGCCCCCAAAGCCCCACAAACGAA
AGACMCATCTTCATCACCCCCATTCAGAAAAAGGACTCATACTGCTTTCA
TCTTCAGAGGAGGAGCTACAATCCACACCTGACTGCACAACATCATGCGA
AGAATTTGAAAGTGAATCCATTTCCGAAAAAGGTAAGAGGTTGAGGGGTT
TTTATTTAATTATATATATAATAATGTTCCGTTGAAGCACGTCTCTTCTC
CATAAGAAGGAGAATATATGTACATATTTGCCTTTTGTTTCCTTTTGCAT
TCGTTAGATTCCCAAAATATGAATTGA
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