EMLSAG00000002641, EMLSAG00000002641-685407 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Homology
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:Insr "insulin receptor" species:10090 "Mus musculus" [GO:0000166 "nucleotide binding" evidence=IEA] [GO:0000187 "activation of MAPK activity" evidence=ISO] [GO:0001933 "negative regulation of protein phosphorylation" evidence=ISO] [GO:0001934 "positive regulation of protein phosphorylation" evidence=ISO] [GO:0003007 "heart morphogenesis" evidence=ISO] [GO:0004672 "protein kinase activity" evidence=ISO] [GO:0004713 "protein tyrosine kinase activity" evidence=ISO] [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=ISO] [GO:0005009 "insulin-activated receptor activity" evidence=ISO] [GO:0005159 "insulin-like growth factor receptor binding" evidence=ISO] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=ISO] [GO:0005525 "GTP binding" evidence=ISO] [GO:0005634 "nucleus" evidence=ISO] [GO:0005768 "endosome" evidence=ISO] [GO:0005829 "cytosol" evidence=ISO] [GO:0005886 "plasma membrane" evidence=ISO;IDA] [GO:0005887 "integral component of plasma membrane" evidence=ISO] [GO:0005899 "insulin receptor complex" evidence=ISO] [GO:0005901 "caveola" evidence=ISO;IDA] [GO:0006355 "regulation of transcription, DNA-templated" evidence=ISO] [GO:0006468 "protein phosphorylation" evidence=ISO] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA] [GO:0007186 "G-protein coupled receptor signaling pathway" evidence=ISO] [GO:0008284 "positive regulation of cell proliferation" evidence=ISO] [GO:0008286 "insulin receptor signaling pathway" evidence=ISO;IMP] [GO:0008544 "epidermis development" evidence=IMP] [GO:0009887 "organ morphogenesis" evidence=IMP] [GO:0010310 "regulation of hydrogen peroxide metabolic process" evidence=ISO] [GO:0010560 "positive regulation of glycoprotein biosynthetic process" evidence=ISO] [GO:0010629 "negative regulation of gene expression" evidence=ISO] [GO:0016020 "membrane" evidence=ISO;IDA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016301 "kinase activity" evidence=IEA] [GO:0016310 "phosphorylation" evidence=IEA] [GO:0016740 "transferase activity" evidence=IEA] [GO:0016772 "transferase activity, transferring phosphorus-containing groups" evidence=IEA] [GO:0018108 "peptidyl-tyrosine phosphorylation" evidence=ISO] [GO:0019087 "transformation of host cell by virus" evidence=ISO] [GO:0019901 "protein kinase binding" evidence=ISO] [GO:0019903 "protein phosphatase binding" evidence=ISO] [GO:0019904 "protein domain specific binding" evidence=ISO] [GO:0023014 "signal transduction by phosphorylation" evidence=ISO] [GO:0030238 "male sex determination" evidence=IMP] [GO:0030335 "positive regulation of cell migration" evidence=ISO] [GO:0031017 "exocrine pancreas development" evidence=IMP] [GO:0031405 "lipoic acid binding" evidence=ISO] [GO:0031994 "insulin-like growth factor I binding" evidence=ISO] [GO:0031995 "insulin-like growth factor II binding" evidence=ISO] [GO:0032147 "activation of protein kinase activity" evidence=ISO] [GO:0032148 "activation of protein kinase B activity" evidence=ISO] [GO:0032403 "protein complex binding" evidence=ISO] [GO:0032410 "negative regulation of transporter activity" evidence=ISO] [GO:0032869 "cellular response to insulin stimulus" evidence=ISO] [GO:0034612 "response to tumor necrosis factor" evidence=ISO] [GO:0035556 "intracellular signal transduction" evidence=ISO] [GO:0042169 "SH2 domain binding" evidence=ISO] [GO:0042327 "positive regulation of phosphorylation" evidence=ISO] [GO:0042593 "glucose homeostasis" evidence=ISO] [GO:0043231 "intracellular membrane-bounded organelle" evidence=ISO] [GO:0043235 "receptor complex" evidence=ISO] [GO:0043410 "positive regulation of MAPK cascade" evidence=ISO] [GO:0043423 "3-phosphoinositide-dependent protein kinase binding" evidence=ISO] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=ISO] [GO:0043559 "insulin binding" evidence=ISO] [GO:0043560 "insulin receptor substrate binding" evidence=ISO] [GO:0045202 "synapse" evidence=ISO] [GO:0045429 "positive regulation of nitric oxide biosynthetic process" evidence=ISO] [GO:0045725 "positive regulation of glycogen biosynthetic process" evidence=ISO;IMP] [GO:0045740 "positive regulation of DNA replication" evidence=ISO] [GO:0045821 "positive regulation of glycolytic process" evidence=ISO] [GO:0045840 "positive regulation of mitosis" evidence=ISO;IMP] [GO:0045995 "regulation of embryonic development" evidence=ISO] [GO:0046326 "positive regulation of glucose import" evidence=ISO] [GO:0046777 "protein autophosphorylation" evidence=ISO] [GO:0048639 "positive regulation of developmental growth" evidence=ISO] [GO:0051290 "protein heterotetramerization" evidence=ISO] [GO:0051425 "PTB domain binding" evidence=ISO] [GO:0051897 "positive regulation of protein kinase B signaling" evidence=ISO] [GO:0060267 "positive regulation of respiratory burst" evidence=ISO] [GO:0070062 "extracellular vesicular exosome" evidence=ISO] [GO:0071363 "cellular response to growth factor stimulus" evidence=IDA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 MGI:MGI:96575 GO:GO:0005525 GO:GO:0005524 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0006355 GO:GO:0035556 eggNOG:COG0515 GO:GO:0005901 GO:GO:0045821 GO:GO:0003007 GO:GO:0071363 BRENDA:2.7.10.1 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0043235 GO:GO:0007186 GO:GO:0000187 GO:GO:0046777 GO:GO:0042593 GO:GO:0009887 GO:GO:0042169 GO:GO:0032148 GO:GO:0030335 GO:GO:0051897 GO:GO:0045840 GO:GO:0051290 GO:GO:0045429 GO:GO:0045725 GO:GO:0008544 TreeFam:TF351636 GO:GO:0045740 PDB:1LK2 PDBsum:1LK2 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0045995 GO:GO:0031017 GO:GO:0043559 GO:GO:0048639 GO:GO:0043548 GO:GO:0030238 Gene3D:3.80.20.20 GO:GO:0004716 GO:GO:0060267 GO:GO:0043560 GO:GO:0019087 HOGENOM:HOG000038045 HOVERGEN:HBG006134 OrthoDB:EOG73RB9N GeneTree:ENSGT00740000115313 KO:K04527 GO:GO:0005009 GO:GO:0051425 GO:GO:0005899 CTD:3643 OMA:CPERVTD ChiTaRS:INSR EMBL:J05149 EMBL:AC168068 EMBL:M28869 PIR:A34157 RefSeq:NP_034698.2 UniGene:Mm.268003 ProteinModelPortal:P15208 SMR:P15208 BioGrid:200774 DIP:DIP-41452N IntAct:P15208 MINT:MINT-1516207 BindingDB:P15208 ChEMBL:CHEMBL3187 PhosphoSite:P15208 PaxDb:P15208 PRIDE:P15208 Ensembl:ENSMUST00000091291 GeneID:16337 KEGG:mmu:16337 InParanoid:P15208 EvolutionaryTrace:P15208 NextBio:289438 PRO:PR:P15208 ArrayExpress:P15208 CleanEx:MM_INSR Genevestigator:P15208 Uniprot:P15208) HSP 1 Score: 449.514 bits (1155), Expect = 3.034e-132 Identity = 366/1145 (31.97%), Postives = 546/1145 (47.69%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQ-----NSVYKADEWEVPRNSVELLEELGNGCFGMVHKG---IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C KECLG C P +C +C++F C TCP P+ F DW C++ C++ + + K + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR L I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P + + + L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ + S K + DS C C + ++ E S F D + N +F + PS RK+RSL +++ ++ F V + IV S E+ + GL+HF YR+ L+AC++D P++RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S +SVY DEWEVPR + LL ELG G FGMV++G I + +R AVKTV + A+ E I FL EA+VMK
Sbjct: 33 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDVCPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHKECLGNCSEPDDPTKCVACRNFYLDGQ----CVETCPPPYYHFQDWRCVNFSFCQDLHFKCRN---SRKPGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAED-SELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVF----VPRPS-------------RKRRSL----EEVGNVTATTLTLPDFPNVSSTIVPTSQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDS----PDERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETR-VAVKTVNESASLRERIEFLNEASVMK 1069
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:Insr "Insulin receptor" species:10116 "Rattus norvegicus" [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA] [GO:0009749 "response to glucose" evidence=IEP] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0032868 "response to insulin" evidence=IEP] [GO:0042327 "positive regulation of phosphorylation" evidence=IDA] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 RGD:2917 GO:GO:0016021 GO:GO:0005829 GO:GO:0005886 GO:GO:0005524 GO:GO:0005634 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0032403 GO:GO:0014823 GO:GO:0032355 GO:GO:0045471 eggNOG:COG0515 GO:GO:0045202 GO:GO:0005768 GO:GO:0009749 BRENDA:2.7.10.1 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0051384 GO:GO:0046777 GO:GO:0042593 GO:GO:0034612 GO:GO:0010042 GO:GO:0033574 GO:GO:0010629 GO:GO:0051290 GO:GO:0045444 GO:GO:0042327 GO:GO:0033280 GO:GO:0001933 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0010560 GO:GO:0010310 GO:GO:0043559 GO:GO:0019903 Gene3D:3.80.20.20 GO:GO:0043423 GO:GO:0031405 GO:GO:0043560 HOGENOM:HOG000038045 HOVERGEN:HBG006134 GO:GO:0005009 EMBL:M29014 EMBL:AF005776 EMBL:AF005777 EMBL:AH004882 EMBL:AH004883 EMBL:U80633 PIR:A36080 UniGene:Rn.9876 ProteinModelPortal:P15127 SMR:P15127 IntAct:P15127 MINT:MINT-1348005 BindingDB:P15127 ChEMBL:CHEMBL5486 PhosphoSite:P15127 PaxDb:P15127 PRIDE:P15127 UCSC:RGD:2917 InParanoid:P15127 NextBio:13948910 PRO:PR:P15127 Genevestigator:P15127 GO:GO:0032410 Uniprot:P15127) HSP 1 Score: 449.514 bits (1155), Expect = 4.344e-132 Identity = 363/1146 (31.68%), Postives = 545/1146 (47.56%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQ-----NSVYKADEWEVPRNSVELLEELGNGCFGMVHKG----IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C KECLG C P +C +C++F C TCP P+ F DW C++ C++ Y + K + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR L I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P + + + L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ + S K + DS C C + ++ E S F D + N +F S+ + + D+ RK+RSL +++ ++ F + + I S E+ + GL+HF YR+ L+AC++D P +R V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S +SVY DEWEVPR + LL ELG G FGMV++G I G ++ AVKTV + A+ E I FL EA+VMK
Sbjct: 32 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDYVEDNYIVLNKDDNEE-CGDVCPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHKECLGNCSEPDDPTKCVACRNFYLDGQ----CVETCPPPYYHFQDWRCVNFSFCQDLHYKCRN---SRKPGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL--EIGNYSFYALDNQNLRQLWDWNKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAED-SELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAEDTRPS-----RKRRSL----EEVGNVTATTPTLPDFPNISSTIAPTSHEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDS----PEERSGVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKG--EVETRVAVKTVNESASLRERIEFLNEASVMK 1080
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:Insr "insulin receptor" species:10116 "Rattus norvegicus" [GO:0000187 "activation of MAPK activity" evidence=IEA;ISO] [GO:0001933 "negative regulation of protein phosphorylation" evidence=IMP] [GO:0001934 "positive regulation of protein phosphorylation" evidence=ISO] [GO:0003007 "heart morphogenesis" evidence=IEA;ISO] [GO:0004672 "protein kinase activity" evidence=IDA] [GO:0004713 "protein tyrosine kinase activity" evidence=ISO;IDA] [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA;ISO] [GO:0005009 "insulin-activated receptor activity" evidence=IEA;ISO;IMP;IDA] [GO:0005159 "insulin-like growth factor receptor binding" evidence=IEA;ISO] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA;ISO] [GO:0005525 "GTP binding" evidence=IEA;ISO] [GO:0005634 "nucleus" evidence=IDA] [GO:0005768 "endosome" evidence=IDA] [GO:0005829 "cytosol" evidence=IDA] [GO:0005886 "plasma membrane" evidence=ISO;IDA] [GO:0005887 "integral component of plasma membrane" evidence=ISO] [GO:0005899 "insulin receptor complex" evidence=IEA;ISO] [GO:0005901 "caveola" evidence=IEA;ISO] [GO:0006355 "regulation of transcription, DNA-templated" evidence=IEA;ISO] [GO:0006468 "protein phosphorylation" evidence=IDA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA] [GO:0007186 "G-protein coupled receptor signaling pathway" evidence=IEA;ISO] [GO:0008284 "positive regulation of cell proliferation" evidence=ISO] [GO:0008286 "insulin receptor signaling pathway" evidence=ISO;IMP;IDA] [GO:0008544 "epidermis development" evidence=ISO] [GO:0009725 "response to hormone" evidence=IEP] [GO:0009749 "response to glucose" evidence=IEP] [GO:0009887 "organ morphogenesis" evidence=ISO] [GO:0010042 "response to manganese ion" evidence=IEP] [GO:0010310 "regulation of hydrogen peroxide metabolic process" evidence=IDA] [GO:0010560 "positive regulation of glycoprotein biosynthetic process" evidence=IMP] [GO:0010629 "negative regulation of gene expression" evidence=IMP] [GO:0014823 "response to activity" evidence=IEP] [GO:0016020 "membrane" evidence=ISO] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0018108 "peptidyl-tyrosine phosphorylation" evidence=ISO;IMP] [GO:0019087 "transformation of host cell by virus" evidence=IEA;ISO] [GO:0019901 "protein kinase binding" evidence=IPI] [GO:0019903 "protein phosphatase binding" evidence=IMP] [GO:0019904 "protein domain specific binding" evidence=IPI] [GO:0023014 "signal transduction by phosphorylation" evidence=ISO] [GO:0030238 "male sex determination" evidence=IEA;ISO] [GO:0030335 "positive regulation of cell migration" evidence=IEA;ISO] [GO:0031017 "exocrine pancreas development" evidence=IEA;ISO] [GO:0031405 "lipoic acid binding" evidence=IPI] [GO:0031667 "response to nutrient levels" evidence=IEP] [GO:0031994 "insulin-like growth factor I binding" evidence=IEA;ISO] [GO:0031995 "insulin-like growth factor II binding" evidence=IEA;ISO] [GO:0032147 "activation of protein kinase activity" evidence=ISO] [GO:0032148 "activation of protein kinase B activity" evidence=IEA;ISO] [GO:0032355 "response to estradiol" evidence=IEP] [GO:0032403 "protein complex binding" evidence=IDA] [GO:0032410 "negative regulation of transporter activity" evidence=IMP] [GO:0032868 "response to insulin" evidence=IEP] [GO:0032869 "cellular response to insulin stimulus" evidence=ISO] [GO:0033280 "response to vitamin D" evidence=IEP] [GO:0033574 "response to testosterone" evidence=IEP] [GO:0034612 "response to tumor necrosis factor" evidence=IMP] [GO:0042169 "SH2 domain binding" evidence=IEA;ISO] [GO:0042327 "positive regulation of phosphorylation" evidence=IDA] [GO:0042593 "glucose homeostasis" evidence=IEA;ISO;IDA] [GO:0043231 "intracellular membrane-bounded organelle" evidence=IDA] [GO:0043235 "receptor complex" evidence=ISO] [GO:0043410 "positive regulation of MAPK cascade" evidence=ISO] [GO:0043423 "3-phosphoinositide-dependent protein kinase binding" evidence=IDA] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=IEA;ISO] [GO:0043559 "insulin binding" evidence=IEA;ISO;IDA;IMP] [GO:0043560 "insulin receptor substrate binding" evidence=IEA;ISO;IMP] [GO:0045202 "synapse" evidence=IDA] [GO:0045429 "positive regulation of nitric oxide biosynthetic process" evidence=IEA;ISO] [GO:0045444 "fat cell differentiation" evidence=IEP] [GO:0045471 "response to ethanol" evidence=IEP] [GO:0045725 "positive regulation of glycogen biosynthetic process" evidence=IEA;ISO] [GO:0045740 "positive regulation of DNA replication" evidence=IEA;ISO] [GO:0045821 "positive regulation of glycolytic process" evidence=IEA;ISO] [GO:0045840 "positive regulation of mitosis" evidence=IEA;ISO] [GO:0045995 "regulation of embryonic development" evidence=IEA;ISO] [GO:0046326 "positive regulation of glucose import" evidence=ISO] [GO:0046777 "protein autophosphorylation" evidence=IEA;ISO;IMP;IDA] [GO:0048639 "positive regulation of developmental growth" evidence=IEA;ISO] [GO:0051290 "protein heterotetramerization" evidence=IEA;ISO;IDA] [GO:0051384 "response to glucocorticoid" evidence=IEP] [GO:0051425 "PTB domain binding" evidence=IEA;ISO] [GO:0051897 "positive regulation of protein kinase B signaling" evidence=IEA;ISO] [GO:0060267 "positive regulation of respiratory burst" evidence=IEA;ISO] [GO:0070062 "extracellular vesicular exosome" evidence=ISO] [GO:0071363 "cellular response to growth factor stimulus" evidence=IEA;ISO] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 RGD:2917 GO:GO:0016021 GO:GO:0005829 GO:GO:0005886 GO:GO:0005524 GO:GO:0005634 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0032403 GO:GO:0014823 GO:GO:0032355 GO:GO:0045471 eggNOG:COG0515 GO:GO:0045202 GO:GO:0005768 GO:GO:0009749 BRENDA:2.7.10.1 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0051384 GO:GO:0046777 GO:GO:0042593 GO:GO:0034612 GO:GO:0010042 GO:GO:0033574 GO:GO:0010629 GO:GO:0051290 GO:GO:0045444 GO:GO:0042327 GO:GO:0033280 GO:GO:0001933 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0010560 GO:GO:0010310 GO:GO:0043559 GO:GO:0019903 Gene3D:3.80.20.20 GO:GO:0043423 GO:GO:0031405 GO:GO:0043560 HOGENOM:HOG000038045 HOVERGEN:HBG006134 GO:GO:0005009 EMBL:M29014 EMBL:AF005776 EMBL:AF005777 EMBL:AH004882 EMBL:AH004883 EMBL:U80633 PIR:A36080 UniGene:Rn.9876 ProteinModelPortal:P15127 SMR:P15127 IntAct:P15127 MINT:MINT-1348005 BindingDB:P15127 ChEMBL:CHEMBL5486 PhosphoSite:P15127 PaxDb:P15127 PRIDE:P15127 UCSC:RGD:2917 InParanoid:P15127 NextBio:13948910 PRO:PR:P15127 Genevestigator:P15127 GO:GO:0032410 Uniprot:P15127) HSP 1 Score: 449.514 bits (1155), Expect = 4.344e-132 Identity = 363/1146 (31.68%), Postives = 545/1146 (47.56%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQ-----NSVYKADEWEVPRNSVELLEELGNGCFGMVHKG----IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C KECLG C P +C +C++F C TCP P+ F DW C++ C++ Y + K + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR L I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P + + + L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ + S K + DS C C + ++ E S F D + N +F S+ + + D+ RK+RSL +++ ++ F + + I S E+ + GL+HF YR+ L+AC++D P +R V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S +SVY DEWEVPR + LL ELG G FGMV++G I G ++ AVKTV + A+ E I FL EA+VMK
Sbjct: 32 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDYVEDNYIVLNKDDNEE-CGDVCPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHKECLGNCSEPDDPTKCVACRNFYLDGQ----CVETCPPPYYHFQDWRCVNFSFCQDLHYKCRN---SRKPGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL--EIGNYSFYALDNQNLRQLWDWNKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAED-SELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAEDTRPS-----RKRRSL----EEVGNVTATTPTLPDFPNISSTIAPTSHEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDS----PEERSGVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKG--EVETRVAVKTVNESASLRERIEFLNEASVMK 1080
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:INSR "Insulin receptor" species:9606 "Homo sapiens" [GO:0000187 "activation of MAPK activity" evidence=IMP] [GO:0001934 "positive regulation of protein phosphorylation" evidence=IDA] [GO:0003007 "heart morphogenesis" evidence=IMP] [GO:0004713 "protein tyrosine kinase activity" evidence=IDA;IMP] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IDA] [GO:0005009 "insulin-activated receptor activity" evidence=IDA] [GO:0005159 "insulin-like growth factor receptor binding" evidence=IDA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IDA] [GO:0005525 "GTP binding" evidence=IDA] [GO:0005886 "plasma membrane" evidence=IC;TAS] [GO:0005887 "integral component of plasma membrane" evidence=IDA] [GO:0005899 "insulin receptor complex" evidence=IMP] [GO:0005901 "caveola" evidence=IDA] [GO:0005975 "carbohydrate metabolic process" evidence=IEA] [GO:0006355 "regulation of transcription, DNA-templated" evidence=IMP] [GO:0007186 "G-protein coupled receptor signaling pathway" evidence=IDA] [GO:0008284 "positive regulation of cell proliferation" evidence=IC;IDA] [GO:0008286 "insulin receptor signaling pathway" evidence=IDA;TAS] [GO:0010008 "endosome membrane" evidence=TAS] [GO:0016020 "membrane" evidence=IDA] [GO:0018108 "peptidyl-tyrosine phosphorylation" evidence=IDA] [GO:0019087 "transformation of host cell by virus" evidence=IMP] [GO:0023014 "signal transduction by phosphorylation" evidence=IDA] [GO:0030238 "male sex determination" evidence=IEA] [GO:0030335 "positive regulation of cell migration" evidence=IMP] [GO:0031017 "exocrine pancreas development" evidence=IEA] [GO:0031994 "insulin-like growth factor I binding" evidence=IPI] [GO:0031995 "insulin-like growth factor II binding" evidence=IPI] [GO:0032147 "activation of protein kinase activity" evidence=IMP] [GO:0032148 "activation of protein kinase B activity" evidence=IDA] [GO:0032869 "cellular response to insulin stimulus" evidence=IDA] [GO:0042169 "SH2 domain binding" evidence=IPI] [GO:0042593 "glucose homeostasis" evidence=IMP] [GO:0043235 "receptor complex" evidence=IDA] [GO:0043410 "positive regulation of MAPK cascade" evidence=IMP] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=IPI] [GO:0043559 "insulin binding" evidence=IDA;IPI] [GO:0043560 "insulin receptor substrate binding" evidence=IPI] [GO:0045429 "positive regulation of nitric oxide biosynthetic process" evidence=IMP] [GO:0045725 "positive regulation of glycogen biosynthetic process" evidence=IDA] [GO:0045740 "positive regulation of DNA replication" evidence=IMP] [GO:0045821 "positive regulation of glycolytic process" evidence=IMP] [GO:0045840 "positive regulation of mitosis" evidence=IMP] [GO:0045995 "regulation of embryonic development" evidence=IMP] [GO:0046326 "positive regulation of glucose import" evidence=IDA;NAS] [GO:0046777 "protein autophosphorylation" evidence=IMP;IDA] [GO:0048639 "positive regulation of developmental growth" evidence=IMP] [GO:0051290 "protein heterotetramerization" evidence=IDA] [GO:0051425 "PTB domain binding" evidence=IPI] [GO:0051897 "positive regulation of protein kinase B signaling" evidence=IMP] [GO:0060267 "positive regulation of respiratory burst" evidence=IDA] [GO:0070062 "extracellular vesicular exosome" evidence=IDA] [GO:0071363 "cellular response to growth factor stimulus" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 GO:GO:0005525 GO:GO:0005524 GO:GO:0070062 Reactome:REACT_111102 GO:GO:0005159 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0006355 GO:GO:0005975 eggNOG:COG0515 GO:GO:0008284 GO:GO:0005901 GO:GO:0045821 GO:GO:0003007 GO:GO:0071363 BRENDA:2.7.10.1 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0007186 GO:GO:0000187 GO:GO:0046777 GO:GO:0042593 GO:GO:0046326 GO:GO:0010008 GO:GO:0032148 GO:GO:0030335 GO:GO:0051897 MIM:125853 GO:GO:0045840 GO:GO:0051290 GO:GO:0045429 GO:GO:0045725 TreeFam:TF351636 GO:GO:0045740 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 DrugBank:DB00047 DrugBank:DB00030 DrugBank:DB00071 GO:GO:0045995 GO:GO:0031017 GO:GO:0043559 GO:GO:0048639 GO:GO:0030238 Gene3D:3.80.20.20 GO:GO:0004716 GO:GO:0060267 PDB:2AUH PDBsum:2AUH GO:GO:0019087 HOGENOM:HOG000038045 HOVERGEN:HBG006134 OrthoDB:EOG73RB9N KO:K04527 GO:GO:0005009 GO:GO:0005899 EMBL:M10051 EMBL:X02160 EMBL:M32972 EMBL:M23100 EMBL:M32823 EMBL:M32824 EMBL:M32825 EMBL:M32826 EMBL:M32827 EMBL:M32828 EMBL:M32829 EMBL:M32830 EMBL:M32831 EMBL:M32832 EMBL:M32833 EMBL:M32834 EMBL:M32835 EMBL:M32836 EMBL:M32837 EMBL:M32838 EMBL:M32839 EMBL:M32840 EMBL:M32841 EMBL:M32842 EMBL:AC010311 EMBL:AC010526 EMBL:AC010606 EMBL:AC125387 EMBL:BC117172 EMBL:J03466 EMBL:J05043 EMBL:M76592 EMBL:AB208861 EMBL:M24555 EMBL:M29929 EMBL:M29930 EMBL:M27197 EMBL:M27195 PIR:A37348 RefSeq:NP_000199.2 RefSeq:NP_001073285.1 UniGene:Hs.465744 PDB:1GAG PDB:1I44 PDB:1IR3 PDB:1IRK PDB:1P14 PDB:1RQQ PDB:2B4S PDB:2DTG PDB:2HR7 PDB:2Z8C PDB:3BU3 PDB:3BU5 PDB:3BU6 PDB:3EKK PDB:3EKN PDB:3ETA PDB:3LOH PDB:3W11 PDB:3W12 PDB:3W13 PDB:3W14 PDB:4IBM PDBsum:1GAG PDBsum:1I44 PDBsum:1IR3 PDBsum:1IRK PDBsum:1P14 PDBsum:1RQQ PDBsum:2B4S PDBsum:2DTG PDBsum:2HR7 PDBsum:2Z8C PDBsum:3BU3 PDBsum:3BU5 PDBsum:3BU6 PDBsum:3EKK PDBsum:3EKN PDBsum:3ETA PDBsum:3LOH PDBsum:3W11 PDBsum:3W12 PDBsum:3W13 PDBsum:3W14 PDBsum:4IBM ProteinModelPortal:P06213 SMR:P06213 BioGrid:109854 DIP:DIP-480N IntAct:P06213 MINT:MINT-1516246 STRING:9606.ENSP00000303830 BindingDB:P06213 ChEMBL:CHEMBL1981 GuidetoPHARMACOLOGY:1800 PhosphoSite:P06213 DMDM:308153655 PaxDb:P06213 PRIDE:P06213 DNASU:3643 Ensembl:ENST00000302850 Ensembl:ENST00000341500 GeneID:3643 KEGG:hsa:3643 UCSC:uc002mgd.1 UCSC:uc002mge.1 CTD:3643 GeneCards:GC19M007112 H-InvDB:HIX0040111 HGNC:HGNC:6091 HPA:HPA036302 MIM:147670 MIM:246200 MIM:262190 MIM:609968 MIM:610549 neXtProt:NX_P06213 Orphanet:263458 Orphanet:2297 Orphanet:508 Orphanet:769 PharmGKB:PA202 InParanoid:P06213 OMA:CPERVTD PhylomeDB:P06213 SABIO-RK:P06213 SignaLink:P06213 ChiTaRS:INSR EvolutionaryTrace:P06213 GeneWiki:Insulin_receptor GenomeRNAi:3643 NextBio:14259 PRO:PR:P06213 ArrayExpress:P06213 Bgee:P06213 CleanEx:HS_INSR Genevestigator:P06213 Uniprot:P06213) HSP 1 Score: 447.588 bits (1150), Expect = 1.600e-131 Identity = 368/1151 (31.97%), Postives = 552/1151 (47.96%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITRE--MKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVP----SEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHN-SSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQN-----SVYKADEWEVPRNSVELLEELGNGCFGMVHKG---IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C ECLG C P +C +C++F C TCP P+ F DW C++ C++ ++ K K+ R+ +Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR LR I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P ++P+ ++ L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ E S K + DS C C + ++ E S F D + N +F S+ + + D RK+RSL G ++ + V +F + V S E+ + GL+HF YR+ L+AC++D P +RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V ++A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S + SVY DEWEV R + LL ELG G FGMV++G I + +R AVKTV + A+ E I FL EA+VMK
Sbjct: 33 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDICPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHSECLGNCSQPDDPTKCVACRNFYLDGR----CVETCPPPYYHFQDWRCVNFSFCQD----LHHKC---KNSRRQGCHQYVIHNNKCIPECPSGYTM----NSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQN------HPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAED-SELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPS-----RKRRSLGDVG----NVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDT----PEERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETR-VAVKTVNESASLRERIEFLNEASVMK 1079
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:INSR "Tyrosine-protein kinase receptor" species:9615 "Canis lupus familiaris" [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=IEA] [GO:0043560 "insulin receptor substrate binding" evidence=IEA] [GO:0046777 "protein autophosphorylation" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 GO:GO:0016021 GO:GO:0005524 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0004714 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0046777 GO:GO:0007169 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 Gene3D:3.80.20.20 OrthoDB:EOG73RB9N GeneTree:ENSGT00740000115313 EMBL:AAEX03012449 EMBL:AAEX03012450 Ensembl:ENSCAFT00000049285 Uniprot:J9NY09) HSP 1 Score: 446.432 bits (1147), Expect = 2.332e-131 Identity = 362/1142 (31.70%), Postives = 544/1142 (47.64%), Query Frame = 0
Query: 242 IKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLIG-KSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVP----SEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSARE-------------YIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQN-----SVYKADEWEVPRNSVELLEELGNGCFGMVHKG----IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+ I +L R L NC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL SL +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C ECLG C P +C +C++F C TCP P+ F DW C++ C++ + N+ + + + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT ++G L IN+ G ++ LE+NLG I+ VSL FFR LR I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T +Y KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P ++P+ ++ L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ E S K + +S C C + ++ E S F D + N +F SS+ G + + RK+R+L G ++ + F + ++ E + GL+HF YR+ L+AC++D P +RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S + SVY DEWEVPR + LL ELG G FGMV++G I G + AVKTV + A+ E I FL EA+VMK
Sbjct: 1 MDIRNNLTR-LHELANCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDICPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHSECLGNCSEPDDPTKCVACRNFYLDGR----CVETCPPPYYHFQDWRCVNFSFCQD---LHNKCKNSRRQGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRT---------SYDKILLKWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQN------HPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAED-SELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRK-----SSSSPGAEDTRPSRKRRALSDAG----NVTAAIPTVPGFPNTSTSTPTSPEEHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDS----PEERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIVKGEPETR--VAVKTVNESASLRERIEFLNEASVMK 1041
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:INSR "Tyrosine-protein kinase receptor" species:9615 "Canis lupus familiaris" [GO:0000187 "activation of MAPK activity" evidence=IEA] [GO:0003007 "heart morphogenesis" evidence=IEA] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA] [GO:0005009 "insulin-activated receptor activity" evidence=IEA] [GO:0005159 "insulin-like growth factor receptor binding" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005525 "GTP binding" evidence=IEA] [GO:0005899 "insulin receptor complex" evidence=IEA] [GO:0005901 "caveola" evidence=IEA] [GO:0006355 "regulation of transcription, DNA-templated" evidence=IEA] [GO:0007186 "G-protein coupled receptor signaling pathway" evidence=IEA] [GO:0019087 "transformation of host cell by virus" evidence=IEA] [GO:0030238 "male sex determination" evidence=IEA] [GO:0030335 "positive regulation of cell migration" evidence=IEA] [GO:0031017 "exocrine pancreas development" evidence=IEA] [GO:0031994 "insulin-like growth factor I binding" evidence=IEA] [GO:0031995 "insulin-like growth factor II binding" evidence=IEA] [GO:0032148 "activation of protein kinase B activity" evidence=IEA] [GO:0042169 "SH2 domain binding" evidence=IEA] [GO:0042593 "glucose homeostasis" evidence=IEA] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=IEA] [GO:0043559 "insulin binding" evidence=IEA] [GO:0043560 "insulin receptor substrate binding" evidence=IEA] [GO:0045429 "positive regulation of nitric oxide biosynthetic process" evidence=IEA] [GO:0045725 "positive regulation of glycogen biosynthetic process" evidence=IEA] [GO:0045740 "positive regulation of DNA replication" evidence=IEA] [GO:0045821 "positive regulation of glycolytic process" evidence=IEA] [GO:0045840 "positive regulation of mitosis" evidence=IEA] [GO:0045995 "regulation of embryonic development" evidence=IEA] [GO:0046777 "protein autophosphorylation" evidence=IEA] [GO:0048639 "positive regulation of developmental growth" evidence=IEA] [GO:0051290 "protein heterotetramerization" evidence=IEA] [GO:0051425 "PTB domain binding" evidence=IEA] [GO:0051897 "positive regulation of protein kinase B signaling" evidence=IEA] [GO:0060267 "positive regulation of respiratory burst" evidence=IEA] [GO:0071363 "cellular response to growth factor stimulus" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 GO:GO:0005525 GO:GO:0005524 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0006355 GO:GO:0035556 GO:GO:0005901 GO:GO:0045821 GO:GO:0003007 GO:GO:0071363 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0007186 GO:GO:0000187 GO:GO:0046777 GO:GO:0042593 GO:GO:0032148 GO:GO:0030335 GO:GO:0051897 GO:GO:0045840 GO:GO:0051290 GO:GO:0045429 GO:GO:0045725 TreeFam:TF351636 GO:GO:0045740 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0045995 GO:GO:0031017 GO:GO:0043559 GO:GO:0048639 GO:GO:0030238 Gene3D:3.80.20.20 GO:GO:0004716 GO:GO:0060267 GO:GO:0019087 GeneTree:ENSGT00740000115313 GO:GO:0005009 GO:GO:0005899 OMA:CPERVTD EMBL:AAEX03012449 EMBL:AAEX03012450 Ensembl:ENSCAFT00000028875 Uniprot:E2RPM8) HSP 1 Score: 446.432 bits (1147), Expect = 3.582e-131 Identity = 368/1169 (31.48%), Postives = 553/1169 (47.31%), Query Frame = 0
Query: 215 SLSGIANFLLLLLMIIPIQSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLIG-KSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVP----SEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSARE-------------YIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQN-----SVYKADEWEVPRNSVELLEELGNGCFGMVHKG----IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
S++ + L L +P+ C I+ +L R L NC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL SL +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C ECLG C P +C +C++F C TCP P+ F DW C++ C++ + N+ + + + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT ++G L IN+ G ++ LE+NLG I+ VSL FFR LR I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S + SYD KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P ++P+ ++ L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ E S K + +S C C + ++ E S F D + N +F P S G + RK+R+L G ++ + F + ++ E + GL+HF YR+ L+AC++D P +RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S + SVY DEWEVPR + LL ELG G FGMV++G I G + AVKTV + A+ E I FL EA+VMK
Sbjct: 10 SVACLLTCLAFCLFFLPV----CPGMDIR--NNLTR-LHELANCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDICPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHSECLGNCSEPDDPTKCVACRNFYLDGR----CVETCPPPYYHFQDWRCVNFSFCQD---LHNKCKNSRRQGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSY------IRTSYD---KILLKWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQN------HPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAED-SELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFV------PRSERFLGSVRDRPSRKRRALSDAG----NVTAAIPTVPGFPNTSTSTPTSPEEHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDS----PEERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIVKGEPETR--VAVKTVNESASLRERIEFLNEASVMK 1070
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:INSR "Tyrosine-protein kinase receptor" species:9913 "Bos taurus" [GO:0000187 "activation of MAPK activity" evidence=IEA] [GO:0003007 "heart morphogenesis" evidence=IEA] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA] [GO:0005009 "insulin-activated receptor activity" evidence=IEA] [GO:0005159 "insulin-like growth factor receptor binding" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005525 "GTP binding" evidence=IEA] [GO:0005899 "insulin receptor complex" evidence=IEA] [GO:0005901 "caveola" evidence=IEA] [GO:0006355 "regulation of transcription, DNA-templated" evidence=IEA] [GO:0007186 "G-protein coupled receptor signaling pathway" evidence=IEA] [GO:0019087 "transformation of host cell by virus" evidence=IEA] [GO:0030238 "male sex determination" evidence=IEA] [GO:0030335 "positive regulation of cell migration" evidence=IEA] [GO:0031017 "exocrine pancreas development" evidence=IEA] [GO:0031994 "insulin-like growth factor I binding" evidence=IEA] [GO:0031995 "insulin-like growth factor II binding" evidence=IEA] [GO:0032148 "activation of protein kinase B activity" evidence=IEA] [GO:0042169 "SH2 domain binding" evidence=IEA] [GO:0042593 "glucose homeostasis" evidence=IEA] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=IEA] [GO:0043559 "insulin binding" evidence=IEA] [GO:0043560 "insulin receptor substrate binding" evidence=IEA] [GO:0045429 "positive regulation of nitric oxide biosynthetic process" evidence=IEA] [GO:0045725 "positive regulation of glycogen biosynthetic process" evidence=IEA] [GO:0045740 "positive regulation of DNA replication" evidence=IEA] [GO:0045821 "positive regulation of glycolytic process" evidence=IEA] [GO:0045840 "positive regulation of mitosis" evidence=IEA] [GO:0045995 "regulation of embryonic development" evidence=IEA] [GO:0046777 "protein autophosphorylation" evidence=IEA] [GO:0048639 "positive regulation of developmental growth" evidence=IEA] [GO:0051290 "protein heterotetramerization" evidence=IEA] [GO:0051425 "PTB domain binding" evidence=IEA] [GO:0051897 "positive regulation of protein kinase B signaling" evidence=IEA] [GO:0060267 "positive regulation of respiratory burst" evidence=IEA] [GO:0071363 "cellular response to growth factor stimulus" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 GO:GO:0005525 GO:GO:0005524 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0006355 GO:GO:0035556 GO:GO:0005901 GO:GO:0045821 GO:GO:0003007 GO:GO:0071363 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0007186 GO:GO:0000187 GO:GO:0046777 GO:GO:0042593 GO:GO:0032148 GO:GO:0030335 GO:GO:0051897 GO:GO:0045840 GO:GO:0051290 GO:GO:0045429 GO:GO:0045725 TreeFam:TF351636 GO:GO:0045740 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0045995 GO:GO:0031017 GO:GO:0043559 GO:GO:0048639 GO:GO:0030238 Gene3D:3.80.20.20 GO:GO:0004716 GO:GO:0060267 GO:GO:0019087 OrthoDB:EOG73RB9N GeneTree:ENSGT00740000115313 GO:GO:0005009 GO:GO:0005899 OMA:CPERVTD EMBL:DAAA02019498 EMBL:DAAA02019495 EMBL:DAAA02019496 EMBL:DAAA02019497 Ensembl:ENSBTAT00000016858 ArrayExpress:F1MV64 Uniprot:F1MV64) HSP 1 Score: 437.187 bits (1123), Expect = 7.705e-128 Identity = 359/1139 (31.52%), Postives = 542/1139 (47.59%), Query Frame = 0
Query: 242 IKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVP----SEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDV------------KKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAV-ALTYFYYKKHDDSEIN---ISSNPRYISQN-----SVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
+ I +L R L NC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T ++G C ECLG C P +C +C++F C TCP P+ F DW C++ C++ + N+ + + + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR LR I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T +Y KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P ++P+ ++ L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ E S K + +S C C + ++ E S F D + N +F S+ + D+ RK+R+L G + + E +V + + GL+HF YR+ L+AC++D P +RCS V + + ADDI G V+H +++V L W P++PN LIV Y + +E + + ++ R +PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + ++ F K+ D + SSNP Y+S + SVY DEWEVPR + LL ELG G FGMV++G I + AVKTV + A+ E I FL EA+VMK
Sbjct: 38 MDIRNNLTR-LHELANCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDICPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCT----SEGL-----CCHSECLGNCSEPDDPTKCVACRNFYLDGR----CVETCPPPYYHFQDWRCVNFSFCQD---LHNKCKNSRRQGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRT---------SYDKILLKWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQN------HPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAED-SELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDARPS-----RKRRALGDVGNVTAAVPTALGLPNTSSTSTPMSSEEHRPFEKVV--NKESLVISGLRHFTGYRIELQACNQDS----PEERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCVSRRHYALERGCRLRGLLPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSICLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG 1080
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:insr "Insulin receptor" species:8355 "Xenopus laevis" [GO:0004713 "protein tyrosine kinase activity" evidence=IDA] [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=TAS] [GO:0005009 "insulin-activated receptor activity" evidence=IDA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005886 "plasma membrane" evidence=IDA] [GO:0005887 "integral component of plasma membrane" evidence=TAS] [GO:0008286 "insulin receptor signaling pathway" evidence=IDA] [GO:0016020 "membrane" evidence=IDA] [GO:0018108 "peptidyl-tyrosine phosphorylation" evidence=IDA;TAS] [GO:0042169 "SH2 domain binding" evidence=ISS;IPI] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=ISS] [GO:0043559 "insulin binding" evidence=ISS;IDA] [GO:0043560 "insulin receptor substrate binding" evidence=ISS] [GO:0046777 "protein autophosphorylation" evidence=IMP;IDA] [GO:0051290 "protein heterotetramerization" evidence=ISS;IDA] [GO:0051425 "PTB domain binding" evidence=ISS;IPI] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 GO:GO:0007275 GO:GO:0005524 GO:GO:0005887 Gene3D:2.60.40.10 InterPro:IPR013783 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0046777 GO:GO:0042169 GO:GO:0051290 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0043559 GO:GO:0043548 Gene3D:3.80.20.20 GO:GO:0043560 HOVERGEN:HBG006134 KO:K04527 GO:GO:0005009 GO:GO:0051425 CTD:3643 EMBL:AJ132556 EMBL:M64660 PIR:B41122 RefSeq:NP_001081702.1 UniGene:Xl.201 ProteinModelPortal:Q9PVZ4 SMR:Q9PVZ4 GeneID:398006 KEGG:xla:398006 Xenbase:XB-GENE-920741 Uniprot:Q9PVZ4) HSP 1 Score: 436.802 bits (1122), Expect = 8.217e-128 Identity = 371/1160 (31.98%), Postives = 545/1160 (46.98%), Query Frame = 0
Query: 211 KFQW-SLSGIANFLLLLLMIIPIQSE--ICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDC--PLLKNHLTRRACWTKATVKEVTFAIPCE-EGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQ-EECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRE-NSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGK----IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPS-KLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSET---DDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFG-GGQKLND-------LNIDVKKRESFVQNAIVAGSA---REYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQS-SSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSE-----INISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGI---FIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
K W SL GI +L+L QS+ IC + I+ + F LE+CT+IEGHL I + +P R L FPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ + EIGL +L +I RG VRIE N LCY+ TI+W +I+ E +I + R +N+ C D C + C L+ L R CWT+ ++V P + +G C DG + C ECLG C P+ EC +C+HF ++ C T CP F W CID C+E NS N + + Y I+ C+ CP G I N TR TC C CPKVC + I S+ + + CT I+G L INL G +I LE+NLG I+ VSL FFR LR I G + YS L+N +++ L+ + K ++ + + GK F H+NP+LC +I +M + + DK DI+ TNGD+A C LT N + S+D + ++ D R LL + +HY+ EA + +N+T+FDG+DACG + W ++D E S + L+ L+P+T YA++V TL+ R GA+S I+YI+T E+ PS L + + S S + + W+PP +PNG +THY + + D + + E YC + K+ S P +D + + + C C E Q + E+ E+ F + + N +F + RK+R LFG L D N+ + + I + + GLKHF YR+ + AC N + + CS V + + AD + G PI + +I+ L W P+DPN LIV Y + I C++ ++ + + PG Y V ++A S+ G G W+E+ + V S++V + P++ +F+L + L Y +K D+E + SSNP Y+S + VY DEWEVPR+ + LL ELG G FGMV++GI I + R AVKTV + A+ E I FL EA+VMK+
Sbjct: 19 KVGWKSLVGIITIFMLILCD---QSDGKICYSMDIR---NNISQFSMLEDCTVIEGHLQILLMFTSKPENF-RGLRFPKLTTITDYLLLFRVYGLESLKDLFPNLTVIRGTRLFFNYALVIFEMVHXKEIGLYNLMNITRGSVRIEKNNELCYLSTIDWSIILDSVEDNYIELNR-DNKEECGDVCPGTVKGKSKCKHTLVNGALVER-CWTQDHCQKVC---PSDCKGSGCLP--DG-----QCCHPECLGSCRKPNDPSECTACRHF----QNEGVCVTACPKGSYQFQGWRCIDFNTCQELNSRCQNSRDNSCPP------YVIHKGECMPDCPSG--YIANSTTR--TCTPCAGPCPKVCTIFQNVKTIDSVTSAQELRGCTVINGSLIINLRGGNNIATELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGEVL--EAGNYSFYALDNPSLRQLWDW-HKHNLTI--------------------IHGKLFFHHNPRLCLSQIHQMEEVTGTKGRQDKNDIATKTNGDQASCE------DNLLTFNFIKTSHDMVL-LRWDAYWPPDYRDLLGFMVHYK---EAPF--QNVTEFDGQDACGSNSWTVVDMDAPE---RSADGKTQSPGCLLRSLKPWTQYAVFVKTLVSGSDEGR--TYGAKSKIIYIRTNETIPSVPLDPFSVSN-STSQIILKWKPPSEPNGNVTHYLVYWQEQPEDSD-LYEVDYCNKGLKLP-------SRTWTPPTEIDENGNENQTEHTSVNKCCPCPKTEFQIQKEQDESAFRKTFENYLHNEVFIPRPV-----------------RKRRDLFGVANGTLPDPVTAPPLFNVSSTRAPDEPEPKIYSQKVWFKESVLISGLKHFTGYRIEIHAC-----NHELSMGCSVAAYVNARTMPEATADKVVG-PITYEY-VEPNIIHLKWQEPKDPNGLIVLYEVHYSRVGGIEEVITCVSQKQYNTDKGGKLRVLTPGNYSVKIRATSLAGNGSWTEQAYFQVPDHPHSNIVKIITGPIIAVFLL--LIVLVYCVVQKKKDAEGPAGPLYTSSNPEYLSASEVYIPDEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVR-VAVKTVNESASLRERIEFLNEASVMKA 1069
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:INSRR "Tyrosine-protein kinase receptor" species:9615 "Canis lupus familiaris" [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA] [GO:0030238 "male sex determination" evidence=IEA] [GO:0031532 "actin cytoskeleton reorganization" evidence=IEA] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=IEA] [GO:0043560 "insulin receptor substrate binding" evidence=IEA] [GO:0046777 "protein autophosphorylation" evidence=IEA] [GO:0071469 "cellular response to alkalinity" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 InterPro:IPR028792 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 GO:GO:0016021 GO:GO:0005524 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0004714 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0046777 GO:GO:0007169 GO:GO:0031532 GO:GO:0071469 TreeFam:TF351636 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0030238 Gene3D:3.80.20.20 OrthoDB:EOG73RB9N GeneTree:ENSGT00740000115313 CTD:3645 PANTHER:PTHR24416:SF107 KO:K05086 OMA:FARTMPH EMBL:AAEX03005312 RefSeq:XP_547526.1 ProteinModelPortal:E2R795 Ensembl:ENSCAFT00000026349 GeneID:490405 KEGG:cfa:490405 NextBio:20863432 Uniprot:E2R795) HSP 1 Score: 421.394 bits (1082), Expect = 1.092e-122 Identity = 325/1119 (29.04%), Postives = 513/1119 (45.84%), Query Frame = 0
Query: 235 EICGNTKIKI-MGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRA--------CWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQ-EECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGK--IRSLDDLHQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLS-GKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLT-VNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIID-KVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETD---DFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIK-NDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSS------VVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPD--KISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
E+C + I+ + +L+R LENC+++EGHL I + R LSFP+L ++TD+ +++ ESL LFPNL V+RG L + YA VV +L ++GL +L +LRG VR+E N LC++ TI+W ++ S HI N+ R C+D C R CWT + + V PC GL C G E C ECLGGC P C +C+H +Q C CP W C+ + C + SI + I+ SC+ CP G + + C KCE CPK C G I S CTH++G L INL G ++ L+ +LG I+ VSL FF++L+ I G + Y+L +L+N+N+Q L ++ + G + GK + +NP+LC + I + + + +KA+I+ TNGD+A C L +++T + + + ++ Y+ + + R LL + ++Y+ E+ + +N T+ G DACG W ++D ++P E G V ++ L+P+T YA++V + + + + QGAQS I+Y++TL + P+ S S + + W+PP++ NG IT+Y + + + + + + YC ++ SN D D D + + C C ++ E E F + + N I S +S N S Q+ + R +R+ G +L + D + +E V + GL+HF YR+ + AC+ + CS VF + AD I G+ + + SS V L W P DPN LI+ Y IK +E+T + C++ + K + L PG Y V+A S+ G G W+E V G V+L V + +FI+ AA+ F+Y + +S + S NP Y S + +Y DEWEVPR + ++ ELG G FGMV++G+ G + + S P A+KTV + A+ E I FL EA+VMK+
Sbjct: 28 EVCPSLDIRSEVAELRR----LENCSVVEGHLQILLMFTATGEDF-RGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVVRGARLFLGYALVVYEMPHLRDVGLPALGAVLRGAVRVEKNQELCHLSTIDWGLLQP-SPSANHIVGNKLREECADVCPGVLGATGQPCARTTFSGHTDYRCWTSSHCQRVC---PCPHGLACTAGG-------ECCHTECLGGCSRPEDPRACVACRHLYFQ----GACHRACPPGTYQHESWRCVTAERCASLRSVPGRTSI----------FGIHEGSCLAQCPPGF----TRNGSSMFCHKCEGLCPKECKVGTKTIDSTQAAQDLAGCTHVEGSLIINLRQGYNLELELQQSLGLIETITGFLKIKHSFALVSLGFFKNLKLIRGDAM--VDGNYTLYVLDNQNLQQLGAW----------------------VAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRAACQTRTLRFVSNVTQADSILLRWERYEPL--------EARDLLSFIVYYK---ESPF--QNATEHTGPDACGTQSWNLLDVELPLSRTQEPG--------VTLAPLKPWTQYAVFVRAITLTTAEDSPH-QGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPIQRNGNITYY-LVLWQRLAEDGDLYLNDYCHRGLRLP------TSNNDPRFDREDGELEAEMEPGC--CPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPKSPWKVTSVNKSPQRHAG--RHRRA--AGALRLGGNSSDFEIQEDKVPR-------ERAVLSGLRHFTEYRIDIHACNHAAHTVG----CSAATFVFARTMPHREADGIPGKVAWEAASKSS--VLLRWLEPPDPNGLILKYEIKYRRLGEEAT-VLCVSRLRYAKFGGVQLALLPPGNYSARVRATSLAGNGSWTESIAFYVPGPEEEDSGGLHVLLTVTPVGLMLFIILAALG---FFYGRKRNSTLYASVNPEYFSASDMYIPDEWEVPREQISIIRELGQGSFGMVYEGLAQGLEAGEESTPVALKTVNELASPRERIEFLKEASVMKA 1036
BLAST of EMLSAG00000002641 vs. GO
Match: - (symbol:IGF1R "Tyrosine-protein kinase receptor" species:9031 "Gallus gallus" [GO:0005010 "insulin-like growth factor-activated receptor activity" evidence=IEA] [GO:0005158 "insulin receptor binding" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0006955 "immune response" evidence=IEA] [GO:0007420 "brain development" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0030238 "male sex determination" evidence=IEA] [GO:0030335 "positive regulation of cell migration" evidence=IEA] [GO:0030879 "mammary gland development" evidence=IEA] [GO:0031017 "exocrine pancreas development" evidence=IEA] [GO:0031994 "insulin-like growth factor I binding" evidence=IEA] [GO:0042802 "identical protein binding" evidence=IEA] [GO:0043066 "negative regulation of apoptotic process" evidence=IEA] [GO:0043231 "intracellular membrane-bounded organelle" evidence=IEA] [GO:0043410 "positive regulation of MAPK cascade" evidence=IEA] [GO:0043548 "phosphatidylinositol 3-kinase binding" evidence=IEA] [GO:0043559 "insulin binding" evidence=IEA] [GO:0043560 "insulin receptor substrate binding" evidence=IEA] [GO:0045740 "positive regulation of DNA replication" evidence=IEA] [GO:0046328 "regulation of JNK cascade" evidence=IEA] [GO:0046777 "protein autophosphorylation" evidence=IEA] [GO:0048015 "phosphatidylinositol-mediated signaling" evidence=IEA] [GO:0051262 "protein tetramerization" evidence=IEA] [GO:0051389 "inactivation of MAPKK activity" evidence=IEA] [GO:0051897 "positive regulation of protein kinase B signaling" evidence=IEA] [GO:0051898 "negative regulation of protein kinase B signaling" evidence=IEA] [GO:0060740 "prostate gland epithelium morphogenesis" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002011 InterPro:IPR003961 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016246 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00041 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000620 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00239 PROSITE:PS50011 PROSITE:PS50853 SMART:SM00060 SMART:SM00219 GO:GO:0016021 GO:GO:0005524 Gene3D:2.60.40.10 InterPro:IPR013783 GO:GO:0004714 SUPFAM:SSF49265 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0046777 GO:GO:0007169 TreeFam:TF351636 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 Gene3D:3.80.20.20 OrthoDB:EOG73RB9N GeneTree:ENSGT00740000115313 EMBL:AADN03006051 EMBL:AADN03006058 Ensembl:ENSGALT00000011398 PRO:PR:F1NG99 Uniprot:F1NG99) HSP 1 Score: 420.239 bits (1079), Expect = 5.631e-122 Identity = 330/1127 (29.28%), Postives = 525/1127 (46.58%), Query Frame = 0
Query: 236 ICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYC---RDDCPLLK----NHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGP-SQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDL---HQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKD-----EQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLR--------KKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSS----VVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEIN-----ISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIG--PDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+CG + I D+ + K LENC ++EG L I I++ E R FPKL ITD+ +++ ESL+ LFPNLTVIRG +L NYA V+ NL EIGL +L +I RG +RIE N+ LCY+ T++W +I+ +I N+ C D C ++ PL + N+ CWT C++ G E C ECLG C P + C +C+++ ++ C TCP F W C+ + C + + + ++ I+ND C+ CP G ++ + C CE CPK+C GK +++D + + CT + G+L IN+ G +I LE+ +G I+ VSL F ++LR+I G + YS +L+N N+Q L+ D N +T K+ GK + +NPKLC +I M + S K DI+ NG++A C L + N + N K+ +E+ D R L+ + ++Y+ EA + KN+T++DG+DACG + W ++D V P E+ D +L+ L+P+T YA+YV + + + N H+I GA+S+I+YI+T + PS ++ S SS ++I W PP PNG +++Y + ++ D + + YC ++ Y D E++ + P+ +K C P+ + E + + + + V F NSI P +K+ ++ R + R++ G N + + + E V G R I+ L+ F YR+ + +C+ + + CS VF + GAD+I G + + V+L W P +PN LI+ Y IK +E Y+ + HL PG Y VQA S+ G G W+E V+ +S++ + L +++P+ F+ I+ + + Y + KK + + S NP Y S + VY DEWEVPR + + ELG G FGMV++GI G D+ A+KTV + A+ E I FL EA+VMK
Sbjct: 31 VCG-PNVDIRNDIH-ELKRLENCAVVEGFLQILLISKAEDY---RNFRFPKLTVITDYLLLFRVAGLESLSDLFPNLTVIRGRNLFYNYALVIFEMTNLKEIGLHNLRNITRGAIRIEKNSDLCYLSTVDWSLILDAVSNN-YIVGNKPPKECGDLCPGTMEEKPLCEKTSINNEYNYRCWTTNH---------CQKMCPSSCGKRACTDQNECCHPECLGSCTAPDNNTACVACRNYYYE----GVCMPTCPPNTYKFEGWRCVTKEFCSK---------VPATETSDYERFVIHNDECMAECPSG---FIRNGSQSMFCSPCEGPCPKICEDGKTKTIDSVTSAQMLQGCTILKGNLLINIRRGNNIASELENFMGLIETVTGYVKIRHSHALVSLSFLKNLRYILGEE--QVDGNYSFYVLDNHNLQQLW-------------------DWNHHNLTIKE--GKMYFAFNPKLCVSEIYRMEEVSGTKGRQSKGDINPRNNGERASCESHILRFVS-------NTTLKNRIKLTWERYRPPDYRDLISFTVYYK---EAPF--KNVTEYDGQDACGSNSWNMVD-VDLPPNKEN------DPGILLQGLKPWTQYAIYVKAVTLTMMEN-HHIHGAKSEIVYIRTNAAVPSI--PLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQD-SYLYRHNYCSKDKVPIRRYADGTIDTEEATEPTKPEGCGGEKG------------PCCACPKTEAEKQAEKEEAEYRKVFEN-FLHNSIFVPRPD----RKRRDVFRIANATLATRNRNITGADHFTNASDAEESEVEYPFFETKVDGKERTVISH-LQPFTLYRIDIHSCNHEADTLG----CSASNFVFARTMPSEGADNIPG--TVAWEAKEENTVYLKWLEPTNPNGLILMYEIKYGQHGEEKRECVSRQEYKKLGGAKLTHLN-PGNYSARVQATSLAGNGSWTEPVSFYVQPKSANYDNFLHLIIVLPIAFLLIIGGLLIMLYVFNKKRNSDRLGNGVLYASVNPEYFSASDVYVPDEWEVPREKITMCRELGQGSFGMVYEGIAKGVVKDEPETRVAIKTVNESASMRERIEFLNEASVMK 1055
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592759801|gb|GAXK01194612.1| (TSA: Calanus finmarchicus comp89199_c0_seq1 transcribed RNA sequence) HSP 1 Score: 338.576 bits (867), Expect = 1.155e-93 Identity = 247/755 (32.72%), Postives = 357/755 (47.28%), Query Frame = 0
Query: 252 FKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVV---GSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGL------TCYQGNDGTRGSIEKCSKECLGGCYGPSQ-----EECYSC---KHFLWQDNSKNY-CRTTCPSPFLMFNDWICIDIKEC--RENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLIGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNG----LNVSYDNY-QKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKII-----------------------DK------VPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDN 937
K ENC+++EG ++I A S P L E+TDF +++ A+ SL T+FP L VIRG LV YA + N+ +GL SLTHI+ GGVRIE N LCYV+TI W IVV + I I N+ N C D C C L +CW + V +PC G CY + G G CS+EC+GGC Q E C +C +H+ Q +S + CR CPSPF+ + W CI +EC R+ S + + S E Y++Y+ C++ CP G + NK+ C C+ CP C G I S + + K CTHI GD+ IN+I I LE L I VSL FF+SL+ I G + SLTI EN+N+Q LF+ D ++ G+++ FIHYN KLC ++I + + S + ++ +S +NG+K +CS KL++ + G L + Y NY Q + + +T +I ALL Y I+YR + E Y K +++++G D CGG W I+ DK +P E + G + + +PYT YA+YV T+M + +A GAQS+I Y +T ES PS + + E S + + I W P+KP+G+I Y + I+ + + ER YC+ K+ K EQ + DP N
Sbjct: 1455 LKRYENCSVVEGSISITS-ALYSAGDSVMNYSMPNLTEVTDFVLLFRADEIISLETIFPKLAVIRGHKLVQFYALAIYQMKNMETVGLPSLTHIMNGGVRIEKNPNLCYVNTIEWTKIVVQDNDKKSHIEIADNQESNKCLDKCPSKCEL--------SCWNLEQCQRV--LVPCPFGTEYAHQELCYTDDKGEVG--RPCSRECVGGCRDRDQAMNNPEMCVACNHTRHYNEQGDSNPFMCREKCPSPFVAYKSWTCITKQECSSRQVSGFTLSNMLAD-SEEAESFYKVYDGQCVEKCPAGYEPRRNKQDNIWNCTVCKKDCPVNCDGEIINSRESALKLKSCTHIKGDIVINVISGDITPVLEETLRDIKDISGSLKIERSHSLVSLHFFKSLKKIGG-----EGSQKSLTIFENDNLQKLFA------------------DHQKIVLGGEKV---VFIHYNQKLCMKEITQFLDLSDVEMR-EEHSVSSVSNGNKIVCSEEKLDLE---VITGGPDLLRLEYQNYIQTLEIQNQNTINIEALLGYHIYYRELSEEQYQNKGVSKYEGMDVCGGSTWNILFEDDPAKFTIFDNLSTNETASCNDKTEKCLRLPEEGKL-IGKFKYNPVVTYIPNCKPYTPYAIYVTTVMEKQLAGEAT--GAQSEIEYARTNESNPSPVINVKAESPSPNILDISWSRPVKPHGVIEQYYVEISY-LGTGRDVEERDYCE-----KKKDKPEQPKIEPDPVN 3560 HSP 2 Score: 139.813 bits (351), Expect = 4.036e-32 Identity = 100/315 (31.75%), Postives = 155/315 (49.21%), Query Frame = 0
Query: 1018 KLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDR----CSDDLTVFLKVSNKPGADDIK----GRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTG-IYCITAYEF----------IKNDYRYHLPVPGXXXXXXXXXXXXGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINI----SSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+++D +ID + FV + G+ LKH+ Y V + AC K+ + ++ CSD+ + K + AD I I +SS++ ++ W PPQ+PNE IVNY + + +S + CI+ E K Y L G YY+ ++AVS+Y G+W+ +V V S ++L V++ + I A Y YYK+ + I S NP YI VY D+WEV R ++ LEELG G FG+V++G+F P PCA+KTV + +++ + I FL EA+ MK
Sbjct: 3921 RVSDRSIDPYAKRVFVA---IPGNQTSLTVNKLKHYSDYEVRVFACQ--KEQVGEKNKVYRVCSDESILNTKTTFDKNADTINPWNDDEEIATQVGNSSEVTFIRWLPPQNPNERIVNYVLAWSKDTSQSKPYVKCISLSEINEINITHRGVQKTMMEYKLVTEGEYYIRLKAVSLYEEGKWTRWQFVKVNSNRSGIILTVVLLFFGVLITLMAATGGYVYYKRKKEPHGGIWNVSSRNPEYIDTAEVYVVDDWEVERKHIQKLEELGKGSFGLVYRGLFSHPTNGDMPCAIKTVNEKSSYRQRIEFLHEASAMK 4850
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592816144|gb|GAXK01138424.1| (TSA: Calanus finmarchicus comp102350_c1_seq4 transcribed RNA sequence) HSP 1 Score: 85.1149 bits (209), Expect = 4.046e-16 Identity = 85/362 (23.48%), Postives = 153/362 (42.27%), Query Frame = 0
Query: 239 NTKIKIMGDLQRDFKALE----NCTIIEGHLAIYDIAEVEPSALSRKLSF-PKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVM------NYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEG-FIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFA-IPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYND--SCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSI 584
N ++ + + + ++ L NCT ++G+L + + + + LSF +RE+T + ++ + + + P+L ++RG L +A +V + ++ + + +L ILRG V I N LC++ TI WD I+ G ++++ + C + C CW + F+ I C C+ G E C C GGC GP Q +C +CK+F C+ CP P ++N I K R+ K + +E + D +C++ CP K+ D C C+ CPK+C ++ ++ CT ++G L+I
Sbjct: 170 NGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDE-----NLDLSFLEHIREVTGYVLISHVDVRR---IILPSLQIVRGRTLFKLTVQDDEFALIVTL-SKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEIITGQNARYVYVYNFKEPERDCTPCHESC--------ENGCWGEGPNNCQKFSKINC--AAQCHSGRCFGPKPRECCHLFCAGGCTGPKQSDCLACKNFY----DDGVCKQECP-PMQIYNP---IKYKWERDPQ----GKYAYGATCVKECPEHLLKDNGACVRACP------PKKKAVDGECVPCDGPCPKICHFTDTVHAGNIDTFRNCTVLEGSLTI 1144
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592918364|gb|GAXK01040011.1| (TSA: Calanus finmarchicus comp1096578_c0_seq4 transcribed RNA sequence) HSP 1 Score: 65.4698 bits (158), Expect = 1.067e-9 Identity = 39/116 (33.62%), Postives = 60/116 (51.72%), Query Frame = 0
Query: 1201 VPLVFIFILAAAVALTYFYY----KKHDDSEINISSNPR---YISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+ + F+ +LAA + + ++ K++D R +S +V DEWE+PR+ V + +LG G FG V G F DK AVKT+K G++ E + FL EA +MK
Sbjct: 94 ITVAFLIVLAAVIFILLIFFLVQKKRYDMKMAATEERMRSLGLLSPMNVLTLDEWEIPRDRVVINRKLGEGAFGQVCGGEFFIDDKGWVAVAVKTLKTGSSVDEKVDFLSEAEMMK 441
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592918366|gb|GAXK01040009.1| (TSA: Calanus finmarchicus comp1096578_c0_seq2 transcribed RNA sequence) HSP 1 Score: 65.4698 bits (158), Expect = 1.148e-9 Identity = 39/116 (33.62%), Postives = 60/116 (51.72%), Query Frame = 0
Query: 1201 VPLVFIFILAAAVALTYFYY----KKHDDSEINISSNPR---YISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+ + F+ +LAA + + ++ K++D R +S +V DEWE+PR+ V + +LG G FG V G F DK AVKT+K G++ E + FL EA +MK
Sbjct: 94 ITVAFLIVLAAVIFILLIFFLVQKKRYDMKMAATEERMRSLGLLSPMNVLTLDEWEIPRDRVVINRKLGEGAFGQVCGGEFFIDDKGWVAVAVKTLKTGSSVDEKVDFLSEAEMMK 441
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592927002|gb|GAXK01031463.1| (TSA: Calanus finmarchicus comp21810_c3_seq22 transcribed RNA sequence) HSP 1 Score: 58.5362 bits (140), Expect = 8.495e-9 Identity = 31/69 (44.93%), Postives = 42/69 (60.87%), Query Frame = 0
Query: 1241 SVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
SV D+WE+PR+ V + +LG G FGMV+ G D+ AVKT+K G++ E I FL EA +MK
Sbjct: 40 SVLALDDWEMPRDRVVINRKLGEGAFGMVYGGEAFFDDRGWVAVAVKTLKAGSSVEEKIDFLSEADMMK 246
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592927009|gb|GAXK01031457.1| (TSA: Calanus finmarchicus comp21810_c3_seq16 transcribed RNA sequence) HSP 1 Score: 58.5362 bits (140), Expect = 1.117e-8 Identity = 31/69 (44.93%), Postives = 42/69 (60.87%), Query Frame = 0
Query: 1241 SVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
SV D+WE+PR+ V + +LG G FGMV+ G D+ AVKT+K G++ E I FL EA +MK
Sbjct: 40 SVLALDDWEMPRDRVVINRKLGEGAFGMVYGGEAFFDDRGWVAVAVKTLKAGSSVEEKIDFLSEADMMK 246
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592927052|gb|GAXK01031414.1| (TSA: Calanus finmarchicus comp21810_c0_seq7 transcribed RNA sequence) HSP 1 Score: 60.4622 bits (145), Expect = 2.988e-8 Identity = 31/73 (42.47%), Postives = 44/73 (60.27%), Query Frame = 0
Query: 1237 ISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
++ SV D+WE+PR+ V + +LG G FGMV+ G D+ AVKT+K G++ E I FL EA +MK
Sbjct: 122 LTPMSVLALDDWEMPRDRVVINRKLGEGAFGMVYGGEAFFDDRGWVAVAVKTLKAGSSVEEKIDFLSEADMMK 340
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592927058|gb|GAXK01031408.1| (TSA: Calanus finmarchicus comp21810_c0_seq1 transcribed RNA sequence) HSP 1 Score: 60.4622 bits (145), Expect = 3.270e-8 Identity = 31/73 (42.47%), Postives = 44/73 (60.27%), Query Frame = 0
Query: 1237 ISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
++ SV D+WE+PR+ V + +LG G FGMV+ G D+ AVKT+K G++ E I FL EA +MK
Sbjct: 122 LTPMSVLALDDWEMPRDRVVINRKLGEGAFGMVYGGEAFFDDRGWVAVAVKTLKAGSSVEEKIDFLSEADMMK 340
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592918365|gb|GAXK01040010.1| (TSA: Calanus finmarchicus comp1096578_c0_seq3 transcribed RNA sequence) HSP 1 Score: 60.4622 bits (145), Expect = 4.379e-8 Identity = 38/132 (28.79%), Postives = 66/132 (50.00%), Query Frame = 0
Query: 1187 TVKGQSSSVVLYVMVPLVFIFILAAAVAL-----TYFYYKKHDDSEINISSNPR----YISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+ G ++ + + + + F F++A +AL + + K+ D ++ + ++ +V DEWE+ R+ V + +LG G FG V G F DK AVKT+K G++ E + FL EA +MK
Sbjct: 94 VLSGFATHLDIKCQLAITFSFLIALGIALFILMIIFLFQKRRYDLKMAATEERMRSLGLLTPMNVLTLDEWEISRDRVVMNRKLGEGAFGQVCGGEFFIDDKGWVAVAVKTLKTGSSVDEKVDFLSEAEMMK 489
BLAST of EMLSAG00000002641 vs. C. finmarchicus
Match: gi|592918367|gb|GAXK01040008.1| (TSA: Calanus finmarchicus comp1096578_c0_seq1 transcribed RNA sequence) HSP 1 Score: 60.4622 bits (145), Expect = 4.662e-8 Identity = 38/132 (28.79%), Postives = 66/132 (50.00%), Query Frame = 0
Query: 1187 TVKGQSSSVVLYVMVPLVFIFILAAAVAL-----TYFYYKKHDDSEINISSNPR----YISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+ G ++ + + + + F F++A +AL + + K+ D ++ + ++ +V DEWE+ R+ V + +LG G FG V G F DK AVKT+K G++ E + FL EA +MK
Sbjct: 94 VLSGFATHLDIKCQLAITFSFLIALGIALFILMIIFLFQKRRYDLKMAATEERMRSLGLLTPMNVLTLDEWEISRDRVVMNRKLGEGAFGQVCGGEFFIDDKGWVAVAVKTLKTGSSVDEKVDFLSEAEMMK 489
BLAST of EMLSAG00000002641 vs. L. salmonis peptides
Match: EMLSAP00000002641 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1534:13768:20494:-1 gene:EMLSAG00000002641 transcript:EMLSAT00000002641 description:"maker-LSalAtl2s1534-augustus-gene-0.16") HSP 1 Score: 2983.36 bits (7733), Expect = 0.000e+0 Identity = 1433/1433 (100.00%), Postives = 1433/1433 (100.00%), Query Frame = 0
Query: 1 MCINANWTRIRHWSAPERRLKDSNSSISKNKNGSEQLEGVETFLLLPQKSYSFLDLRMSESMMNNKNFVSYSIRREQKVRSRERRKYNLSDEEEEXFSFVTAASSSFSYSSIFLTPNPSSMMVADSTTLDNNNTTFSSFSHFTPKEEADPLRGASSSYNDTPTLKDDGHPQRVPHLNQQEQQHTPRDYSRKRGFRKTSHFFFRFYNRRKFKFQWSLSGIANFLLLLLMIIPIQSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEFCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLIGKSIVDGLESNLGKIDVSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKSERANRQKEEEENAETPLTYPNGSSSGGSVNVTFAGGYPPSNNSDSNGGIVTTGTNLSSSSAISNGHLLSSSIPSSEFQELNRASSIFGGSSGSGSTARLTSKWNKVTTFMRMRNKSGSASGEA 1433
MCINANWTRIRHWSAPERRLKDSNSSISKNKNGSEQLEGVETFLLLPQKSYSFLDLRMSESMMNNKNFVSYSIRREQKVRSRERRKYNLSDEEEEXFSFVTAASSSFSYSSIFLTPNPSSMMVADSTTLDNNNTTFSSFSHFTPKEEADPLRGASSSYNDTPTLKDDGHPQRVPHLNQQEQQHTPRDYSRKRGFRKTSHFFFRFYNRRKFKFQWSLSGIANFLLLLLMIIPIQSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEFCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLIGKSIVDGLESNLGKIDVSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKSERANRQKEEEENAETPLTYPNGSSSGGSVNVTFAGGYPPSNNSDSNGGIVTTGTNLSSSSAISNGHLLSSSIPSSEFQELNRASSIFGGSSGSGSTARLTSKWNKVTTFMRMRNKSGSASGEA
Sbjct: 1 MCINANWTRIRHWSAPERRLKDSNSSISKNKNGSEQLEGVETFLLLPQKSYSFLDLRMSESMMNNKNFVSYSIRREQKVRSRERRKYNLSDEEEEXFSFVTAASSSFSYSSIFLTPNPSSMMVADSTTLDNNNTTFSSFSHFTPKEEADPLRGASSSYNDTPTLKDDGHPQRVPHLNQQEQQHTPRDYSRKRGFRKTSHFFFRFYNRRKFKFQWSLSGIANFLLLLLMIIPIQSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEFCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLIGKSIVDGLESNLGKIDVSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKSERANRQKEEEENAETPLTYPNGSSSGGSVNVTFAGGYPPSNNSDSNGGIVTTGTNLSSSSAISNGHLLSSSIPSSEFQELNRASSIFGGSSGSGSTARLTSKWNKVTTFMRMRNKSGSASGEA 1433
BLAST of EMLSAG00000002641 vs. L. salmonis peptides
Match: EMLSAP00000007374 (pep:novel supercontig:LSalAtl2s:LSalAtl2s41:164202:216377:-1 gene:EMLSAG00000007374 transcript:EMLSAT00000007374 description:"maker-LSalAtl2s41-augustus-gene-2.12") HSP 1 Score: 86.6557 bits (213), Expect = 2.815e-17 Identity = 89/370 (24.05%), Postives = 166/370 (44.86%), Query Frame = 0
Query: 233 QSEICGNTK--IKIMGDLQRDFKALE----NCTIIEGHLAIYDIAEVEPSALSRKLSFPK-LREITDFFIMYNANAFESLATLFPNLTVIRGDDL----VMNYAF-VVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEG-FIHIQR-NENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFA-IPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITE--KSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSI 584
+IC TK + + + + ++ L NCT ++G+L + + + + LSF + +RE+T + ++ + + + + P+L +IRG L V + F +++ + ++ + + +L IL G V I N LC++ TI W+ I+ G G ++++ NE C+ C + C + CW + F+ I C C++G E C C GGC GP Q +C +C++F K C P +N I ++ E Y + E K + ++ N +C++ CP K+T + C C+ CPK C ++ ++ ++ CT I+G ++I
Sbjct: 78 HGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDE-----NLDLSFLQHIREVTGYVLISHVDVRK---IVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTP-CHESC--------QSGCWGEGPSNCQKFSKINCSP--QCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXEC-----PPMQRYNP-IKYRWEKNPEGKYAYGATCVKECPKHLLKD------NGACVRICP------PKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITI 410 HSP 2 Score: 64.3142 bits (155), Expect = 2.103e-10 Identity = 62/234 (26.50%), Postives = 90/234 (38.46%), Query Frame = 0
Query: 251 DFKALENCTIIEGHLAI--------------YDIAEVEPSALSRKLS-FPKLREITDFF-IMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQ 468
+ + +NCT+IEG + I Y P+ +KL F L+E+T + I + F++L F NL VI G L ++ + I L +GL+SL I G V I N LCY INW I+ +Q N+N C + ++H+ C+ +CS E GC+GP C SCK F Q
Sbjct: 394 NIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNL-NAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQEC---------IRQDHM-------------------CD----------------PQCSAE---GCWGPGNNSCLSCKKFQTQ 579
BLAST of EMLSAG00000002641 vs. L. salmonis peptides
Match: EMLSAP00000005080 (pep:novel supercontig:LSalAtl2s:LSalAtl2s268:283763:286301:1 gene:EMLSAG00000005080 transcript:EMLSAT00000005080 description:"maker-LSalAtl2s268-augustus-gene-3.12") HSP 1 Score: 55.4546 bits (132), Expect = 1.017e-7 Identity = 44/150 (29.33%), Postives = 67/150 (44.67%), Query Frame = 0
Query: 1196 VLYVMVPLVFIFILAAAVALTYFYYK---------------KHDDSEI----NISSNPRYISQNSVYKA-----------------DEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
V+Y+++PLV +FI+ ++ Y Y K + EI N + + S+YK ++WE+ R+S+++L LG GCFG V KG I + IS AVKT K+ A E L E ++MK
Sbjct: 190 VVYIILPLVIVFIICISILFFYRSYIFKYIPPRRSTHQCGIKLGEEEIISCMNTNEKNTTSTDKSIYKKTSINSTLTDYTILLDSKEKWEISRHSIKILHMLGEGCFGQVWKGEMI-VEGISSTXAVKTFKESANEVEKKDLLKELSIMK 338
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|408360149|sp|P15208.2|INSR_MOUSE (RecName: Full=Insulin receptor; Short=IR; AltName: CD_antigen=CD220; Contains: RecName: Full=Insulin receptor subunit alpha; Contains: RecName: Full=Insulin receptor subunit beta; Flags: Precursor) HSP 1 Score: 449.514 bits (1155), Expect = 1.863e-133 Identity = 366/1145 (31.97%), Postives = 546/1145 (47.69%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQ-----NSVYKADEWEVPRNSVELLEELGNGCFGMVHKG---IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C KECLG C P +C +C++F C TCP P+ F DW C++ C++ + + K + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR L I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P + + + L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ + S K + DS C C + ++ E S F D + N +F + PS RK+RSL +++ ++ F V + IV S E+ + GL+HF YR+ L+AC++D P++RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S +SVY DEWEVPR + LL ELG G FGMV++G I + +R AVKTV + A+ E I FL EA+VMK
Sbjct: 33 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDVCPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHKECLGNCSEPDDPTKCVACRNFYLDGQ----CVETCPPPYYHFQDWRCVNFSFCQDLHFKCRN---SRKPGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAED-SELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVF----VPRPS-------------RKRRSL----EEVGNVTATTLTLPDFPNVSSTIVPTSQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDS----PDERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETR-VAVKTVNESASLRERIEFLNEASVMK 1069
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|124531|sp|P15127.1|INSR_RAT (RecName: Full=Insulin receptor; Short=IR; AltName: CD_antigen=CD220; Contains: RecName: Full=Insulin receptor subunit alpha; Contains: RecName: Full=Insulin receptor subunit beta; Flags: Precursor) HSP 1 Score: 449.514 bits (1155), Expect = 2.709e-133 Identity = 363/1146 (31.68%), Postives = 545/1146 (47.56%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQ-----NSVYKADEWEVPRNSVELLEELGNGCFGMVHKG----IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C KECLG C P +C +C++F C TCP P+ F DW C++ C++ Y + K + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR L I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P + + + L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ + S K + DS C C + ++ E S F D + N +F S+ + + D+ RK+RSL +++ ++ F + + I S E+ + GL+HF YR+ L+AC++D P +R V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S +SVY DEWEVPR + LL ELG G FGMV++G I G ++ AVKTV + A+ E I FL EA+VMK
Sbjct: 32 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDYVEDNYIVLNKDDNEE-CGDVCPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHKECLGNCSEPDDPTKCVACRNFYLDGQ----CVETCPPPYYHFQDWRCVNFSFCQDLHYKCRN---SRKPGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL--EIGNYSFYALDNQNLRQLWDWNKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAED-SELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAEDTRPS-----RKRRSL----EEVGNVTATTPTLPDFPNISSTIAPTSHEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDS----PEERSGVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKG--EVETRVAVKTVNESASLRERIEFLNEASVMK 1080
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|308153655|sp|P06213.4|INSR_HUMAN (RecName: Full=Insulin receptor; Short=IR; AltName: CD_antigen=CD220; Contains: RecName: Full=Insulin receptor subunit alpha; Contains: RecName: Full=Insulin receptor subunit beta; Flags: Precursor) HSP 1 Score: 447.588 bits (1150), Expect = 1.013e-132 Identity = 368/1151 (31.97%), Postives = 552/1151 (47.96%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITRE--MKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVP----SEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHN-SSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQN-----SVYKADEWEVPRNSVELLEELGNGCFGMVHKG---IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C ECLG C P +C +C++F C TCP P+ F DW C++ C++ ++ K K+ R+ +Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR LR I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P ++P+ ++ L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ E S K + DS C C + ++ E S F D + N +F S+ + + D RK+RSL G ++ + V +F + V S E+ + GL+HF YR+ L+AC++D P +RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V ++A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S + SVY DEWEV R + LL ELG G FGMV++G I + +R AVKTV + A+ E I FL EA+VMK
Sbjct: 33 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDICPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHSECLGNCSQPDDPTKCVACRNFYLDGR----CVETCPPPYYHFQDWRCVNFSFCQD----LHHKC---KNSRRQGCHQYVIHNNKCIPECPSGYTM----NSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQN------HPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAED-SELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPS-----RKRRSLGDVG----NVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDT----PEERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETR-VAVKTVNESASLRERIEFLNEASVMK 1079
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|82175202|sp|Q9PVZ4.1|INSR_XENLA (RecName: Full=Insulin receptor; Short=IR; AltName: Full=XTK-1b; AltName: Full=Xe-InsR; Contains: RecName: Full=Insulin receptor subunit alpha; Contains: RecName: Full=Insulin receptor subunit beta; Flags: Precursor) HSP 1 Score: 436.802 bits (1122), Expect = 5.697e-129 Identity = 371/1160 (31.98%), Postives = 545/1160 (46.98%), Query Frame = 0
Query: 211 KFQW-SLSGIANFLLLLLMIIPIQSE--ICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDC--PLLKNHLTRRACWTKATVKEVTFAIPCE-EGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQ-EECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRE-NSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGK----IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPS-KLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSET---DDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFG-GGQKLND-------LNIDVKKRESFVQNAIVAGSA---REYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQS-SSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSE-----INISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGI---FIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
K W SL GI +L+L QS+ IC + I+ + F LE+CT+IEGHL I + +P R L FPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ + EIGL +L +I RG VRIE N LCY+ TI+W +I+ E +I + R +N+ C D C + C L+ L R CWT+ ++V P + +G C DG + C ECLG C P+ EC +C+HF ++ C T CP F W CID C+E NS N + + Y I+ C+ CP G I N TR TC C CPKVC + I S+ + + CT I+G L INL G +I LE+NLG I+ VSL FFR LR I G + YS L+N +++ L+ + K ++ + + GK F H+NP+LC +I +M + + DK DI+ TNGD+A C LT N + S+D + ++ D R LL + +HY+ EA + +N+T+FDG+DACG + W ++D E S + L+ L+P+T YA++V TL+ R GA+S I+YI+T E+ PS L + + S S + + W+PP +PNG +THY + + D + + E YC + K+ S P +D + + + C C E Q + E+ E+ F + + N +F + RK+R LFG L D N+ + + I + + GLKHF YR+ + AC N + + CS V + + AD + G PI + +I+ L W P+DPN LIV Y + I C++ ++ + + PG Y V ++A S+ G G W+E+ + V S++V + P++ +F+L + L Y +K D+E + SSNP Y+S + VY DEWEVPR+ + LL ELG G FGMV++GI I + R AVKTV + A+ E I FL EA+VMK+
Sbjct: 19 KVGWKSLVGIITIFMLILCD---QSDGKICYSMDIR---NNISQFSMLEDCTVIEGHLQILLMFTSKPENF-RGLRFPKLTTITDYLLLFRVYGLESLKDLFPNLTVIRGTRLFFNYALVIFEMVHXKEIGLYNLMNITRGSVRIEKNNELCYLSTIDWSIILDSVEDNYIELNR-DNKEECGDVCPGTVKGKSKCKHTLVNGALVER-CWTQDHCQKVC---PSDCKGSGCLP--DG-----QCCHPECLGSCRKPNDPSECTACRHF----QNEGVCVTACPKGSYQFQGWRCIDFNTCQELNSRCQNSRDNSCPP------YVIHKGECMPDCPSG--YIANSTTR--TCTPCAGPCPKVCTIFQNVKTIDSVTSAQELRGCTVINGSLIINLRGGNNIATELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGEVL--EAGNYSFYALDNPSLRQLWDW-HKHNLTI--------------------IHGKLFFHHNPRLCLSQIHQMEEVTGTKGRQDKNDIATKTNGDQASCE------DNLLTFNFIKTSHDMVL-LRWDAYWPPDYRDLLGFMVHYK---EAPF--QNVTEFDGQDACGSNSWTVVDMDAPE---RSADGKTQSPGCLLRSLKPWTQYAVFVKTLVSGSDEGR--TYGAKSKIIYIRTNETIPSVPLDPFSVSN-STSQIILKWKPPSEPNGNVTHYLVYWQEQPEDSD-LYEVDYCNKGLKLP-------SRTWTPPTEIDENGNENQTEHTSVNKCCPCPKTEFQIQKEQDESAFRKTFENYLHNEVFIPRPV-----------------RKRRDLFGVANGTLPDPVTAPPLFNVSSTRAPDEPEPKIYSQKVWFKESVLISGLKHFTGYRIEIHAC-----NHELSMGCSVAAYVNARTMPEATADKVVG-PITYEY-VEPNIIHLKWQEPKDPNGLIVLYEVHYSRVGGIEEVITCVSQKQYNTDKGGKLRVLTPGNYSVKIRATSLAGNGSWTEQAYFQVPDHPHSNIVKIITGPIIAVFLL--LIVLVYCVVQKKKDAEGPAGPLYTSSNPEYLSASEVYIPDEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVR-VAVKTVNESASLRERIEFLNEASVMKA 1069
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|2497557|sp|O02466.1|ILPR_BRALA (RecName: Full=Insulin-like peptide receptor; Short=ILP receptor; Contains: RecName: Full=Insulin-like peptide receptor alpha chain; Contains: RecName: Full=Insulin-like peptide receptor beta chain; Flags: Precursor) HSP 1 Score: 431.024 bits (1107), Expect = 8.164e-127 Identity = 349/1149 (30.37%), Postives = 531/1149 (46.21%), Query Frame = 0
Query: 222 FLLLLLMIIPIQSE--ICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVG--SEGFIHIQRNENR--NVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGN--DGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLG-TQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTD-YDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYK--DEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLN-------DLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSK----ESTGIYCITAYEFIKND-YRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSS-------------SVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEIN-----ISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
++ L +++P E IC + I+ + + + LENCT+IEG+L I I E S L+FP L EITD+F++Y +L+ LFPNL VIRG +L NYA VV ++ +IGL SL +I RG VRIE N LCY+ TI+W I S FI R E N C CR P+L++ CW + ++V C E +C GN DG G C + C+GGC GP++ +C +CK+F+ C CP + D CI +EC + V +++++ CI CP G T I N C +CE CPK C GG + SL +++ CT I+G+L I++ G +I+D LE NLG I+ V+LDF RSL+ I GI +E Y+ +L+N N++ LF + ++ DI + DE GK F H+NPKLC I+ M+ + L DIS TNGD+A CS +L I +N S D + + + D R LL Y + YR ++ + + ++DG+DACG WK D P++ + +++ L+P+T YAL V T A GA+SDI+Y +T KP+ + S +++ I W+PP +PNG +THY + R+ D + +R YC+ K + ++ N +++P+N S + + T C+C + E E + +F + + N ++ T +G+++ EL R + Q +N Q + + GL+HF Y + + AC N D CS + AD+I G +V D+ L W P PN ++V+YNI+ + E C+ ++F+++ Y V G Y V +A S G G WS V+ + + S+++ + V + ILA + Y K+ D ++ S NP Y+S + VY DEWEVPR + L+ ELG G FGMV++G + D+ AVKTV + A+ E I FL EA+VMK+
Sbjct: 17 LVIGLGLLVPSNGEEYICDSMDIR---NRVSNLRQLENCTVIEGYLQILLIDFAEEQDYS-GLAFPNLVEITDYFLLYRVRGLTNLSELFPNLAVIRGTNLFFNYALVVFEMLDMQKIGLYSLQNITRGSVRIEKNPNLCYLDTIDWSFIAESGYSNNFIVDNREEEECVNFCPGRCRIKHPVLQD-----LCWAEEHCQKV-----CPE--SCL-GNCRDGISGC---CHENCIGGCDGPTERDCVACKYFV----HNGECLIQCPPDTYQYKDRRCITEEECPNTTNSV---------------WKLHHRKCIPECPSGYTTDINNPR----LCTECEGQCPKSCKGGLVDSLAAAQRFRGCTIIEGELKISIRGGDNIIDELEENLGLIEEVGHYVAIVRSYALVTLDFLRSLKRIRGIQ---KENGYAFYVLDNRNLEKLFDW-DRTDITI---------DE-----------GKLFFHFNPKLCRHVILTMVDKVGLPEHAITDTDISTLTNGDQAQCSFSRLEIEE------INTSKDMI-ILRWSEFRPPDPRDLLSYTVSYRETED-----QGIDEYDGQDACGNTEWKEFDVSPTQTAH------------IITGLKPWTQYALLVKTYT---KAGAREGSGAKSDIVYARTDADKPTHPQDVVVYSNSSNTLIITWKPPNRPNGNVTHYIVKYKRQQEDVAEMEQREYCKGGLKPHRPTQGLEDIVNNEEEPNN-------STIGDGTCCECPKSEDEIRIEEEEAAFQQEFENFLHNNVYHKRENET-----RAGRRRRELPVTARPFY-SNQTVNVTLPSTNRTVPPTPTPNPNPQLETTVWNEHMVVLTGLRHFSEYIIEVIAC-----NADAAVGCSGSAVELARTQADDSADNIPGNITVVE--IKEDMAKLYWPKPDSPNSMVVHYNIEYKKLGSDFNYEQQEPKCVENFKFLQSQGYTISNLVAGNYSVRFRATSFAGNGSWSNYVTFYVEEEDTSPDPQDPQQQVPVSLMIGMGVGFSLLLILAVIFGIWYCTKKRFGDKQMPNGVLYASVNPEYMSSDDVYVPDEWEVPREKITLIRELGQGSFGMVYEGEAKDVVKDEPMVSVAVKTVNESASIRERIEFLNEASVMKT 1051
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|357529496|sp|Q64716.3|INSRR_RAT (RecName: Full=Insulin receptor-related protein; Short=IRR; AltName: Full=IR-related receptor; Flags: Precursor) HSP 1 Score: 417.927 bits (1073), Expect = 1.189e-122 Identity = 318/1102 (28.86%), Postives = 510/1102 (46.28%), Query Frame = 0
Query: 251 DFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDC-----PLLKNHL---TRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQ-EECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGK--IRSLDDLHQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLS-GKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIID-KVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSET---DDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNI--DVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIK-NDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSS-----VVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPD--KISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
+ + LENC+++EGHL I + R LSFP+L ++TD+ +++ ESL LFPNL VIRG L + YA ++ +L +IGL SL +LRG VR+E N LC++ TI+W ++ + G HI N+ C+D C P ++ T CWT + + V PC GL C G E C ECLGGC P C +C+H +Q C TCP + W C+ + C + + + IY SC+ CP G + + C KCE CPK C G I S+ CTH++G L +NL G ++ L+ NLG ++ V+L FF++L+ I G + Y+L +L+N+N+Q L S+ + G + GK + +NP+LC + I ++ + + KA+I+ TNGD+A C L N++ ++ + +E+ + R LL + ++Y+ E+ + +N T+ G DACG W ++D ++P E G V ++ L+P+T YA++V + + + + QGAQS I+Y++TL + P+ S S + + W+PP++ NG IT+Y + + + + + + YC ++ D + +++ DP L+++ C C + E E F + + + I + +S N + Q+ SE R++ L G+ +D I D RE V + GL+HF YR+ + AC+ + CS VF + AD I G+ + + SS I L W P DPN LI+ Y IK +E+T + C++ + K L PG Y V+A S+ G G W++ + G +L + P+ F+ ++ A AL +FY KK + S + S NP Y S + +Y DEWEVPR + ++ ELG G FGMV++G+ G + + S P A+KTV + A+ E + FL EA+VMK+
Sbjct: 41 ELRRLENCSVVEGHLQILLMFAATGEDF-RGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGARLFLGYALIIFEMPHLRDIGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQP-APGANHIVGNKLGEECADVCPGVLGAAGEPCVRTTFGGHTDYRCWTSSHCQRVC---PCPRGLACTVGG-------ECCHSECLGGCSQPEDPRACVACRHLYFQ----GVCLPTCPPGTYQYESWRCVTAELCGHLREVPGHAT----------AFGIYEGSCLAQCPPGF----TRNGSSIFCHKCEGLCPKECKVGTKTIDSVQATQDLVGCTHVEGSLILNLRQGYNLEPELQRNLGLVETITGFLKIKHSFALVTLGFFKNLKLIRGDSM--VDGNYTLYVLDNQNLQQLGSW----------------------VAAGLTIPVGKIYFAFNPRLCLEHIYQLEEVTGTRGRQSKAEINPRTNGDRAACQTRTLRFV-------FNLTEEDRILLRWERYEPLEARDLLSFIVYYK---ESPF--QNATEHVGPDACGTQSWNLLDVELPLSRTQEPG--------VTLAPLKPWTQYAVFVRAITLTTAEDSPH-QGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPVQRNGNITYY-LVLWQRLAEDGDLYINDYCHRGLRLPTSSHDTRFDRE-DP-ALEAEPEQGC------CPCQHSPPGQALPALEAQEVTFQKKFENFLHHAITIPKAPWKVTSINKNPQRDSERHRRETGLLRLGKNNSDFEIHEDKVPRERAVLS-------------GLRHFTEYRIDIHACNHAAHTVG----CSAATFVFARTMPHREADGIPGKVVWKAVGKSSVI--LHWLEPPDPNGLILKYEIKYRRLGEEAT-VLCVSRLRYAKVGGVHLALLPPGNYSAKVRATSLAGNGSWTDGVAFYITGPEEEDTGGLRILLTVTPVGFMLLVMLA-ALGFFYSKKRN-STLYTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKA 1036
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|341940836|sp|Q9WTL4.2|INSRR_MOUSE (RecName: Full=Insulin receptor-related protein; Short=IRR; AltName: Full=IR-related receptor; Contains: RecName: Full=Insulin receptor-related protein alpha chain; Contains: RecName: Full=Insulin receptor-related protein beta chain; Flags: Precursor) HSP 1 Score: 414.846 bits (1065), Expect = 1.378e-121 Identity = 313/1099 (28.48%), Postives = 514/1099 (46.77%), Query Frame = 0
Query: 251 DFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDC-----PLLKNHLTRRA---CWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQ-EECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGK--IRSLDDLHQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLS-GKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIID-KVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSET---DDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIK-NDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTV----KGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPD--KISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
+ + LENC+++EGHL I + R LSFP+L ++TD+ +++ ESL LFPNLTVIRG L + YA ++ +L ++GL SL +LRG VR+E N LC++ TI+W ++ + G HI N+ C+D C P + + R CWT + ++V PC G+ C G D C ECLGGC P C +C+H +Q C CP + W C+ + C + + + + T + IY SC+ CP G + + C KCE CPK C G I S+ CTH++G+L +NL G ++ L+ NLG ++ V+L FF++L+ I G + Y+L +L+N+N+Q L S+ + G + GK + +NP+LC + I ++ + + KA+I+ TNGD+A C L N++ ++ + +E+ + R LL + ++Y+ E+ + +N T+ G DACG W ++D ++P E G V ++ L+P+T YA++V + + + + QGAQS I+Y++TL + P+ S S + + W+PP++ NG IT+Y + + + + + + YC ++ D + +++ DP L+++ C C + E E F + + + I + +S N + Q+ SE R++ L G+ +D I K + AI++G L+HF YR+ + AC+ + CS VF + AD I G+ + SS V L W P DPN LI+ Y IK +E+T + C++ + K L PG Y V+A S+ G G W++ + + + + +++ V V +L AL +FY +K + S + S NP Y S + +Y DEWEVPR + ++ ELG G FGMV++G+ G + + S P A+KTV + A+ E + FL EA+VMK+
Sbjct: 41 ELRRLENCSVVEGHLQILLMFAATGEDF-RGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLTVIRGTRLFLGYALIIFEMPHLRDVGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQP-APGTNHIVGNKLGEECADVCPGVLGAAGEPCSRTTFSGRTDYRCWTSSHCQKVC---PCPRGMACTAGGDC-------CHSECLGGCSQPEDPRACVACRHLYFQ----GVCLRACPPGTYQYESWRCVTAELC------AHLREVPGLATT----FGIYEGSCLAQCPPGF----TRNGSSIFCHKCEGLCPKECKVGTKTIDSVQATQDLVGCTHVEGNLILNLRQGYNLEPELQRNLGLVETITGFLKIKHSFALVTLGFFKNLKLIRGDSM--VDGNYTLYVLDNQNLQQLGSW----------------------VTAGLTIPVGKIYFAFNPRLCLEHIYQLEEVTGTRGRQSKAEINPRTNGDRAACQTRTLRFV-------FNLTEEDRILLRWERYEPLEARDLLSFIVYYK---ESPF--QNATEHVGPDACGTQSWNLLDVELPLSRTQEPG--------VTLAPLKPWTQYAVFVRAITLTTAEDSPH-QGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPVQRNGNITYY-LVLWQRLAEDGDLYINDYCHRGLRLPTSSHDTRFDRE-DP-ALEAEPEQGC------CPCQHSPPGQALPALEAQEVTFQKKFENFLHHAITIPKAPWKVTSINKNPQRDSERHRREAGLLRLGKNNSDFEIQEDKVPR--ERAILSG---------LRHFTEYRIDIHACNHAAHTVG----CSAATFVFARTMPHREADGIPGKVAWKAAGKSS--VTLHWLEPPDPNGLILKYEIKYRRLGEEAT-VLCVSRLRYAKVGGVHLALLPPGNYSAKVRATSLAGNGSWTDGVTFYITDLEEEDTGGMRIFLTVTPVGFMLLVTLAALGFFYSRKRN-STLYTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKA 1036
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|12644000|sp|P14616.2|INSRR_HUMAN (RecName: Full=Insulin receptor-related protein; Short=IRR; AltName: Full=IR-related receptor; Contains: RecName: Full=Insulin receptor-related protein alpha chain; Contains: RecName: Full=Insulin receptor-related protein beta chain; Flags: Precursor) HSP 1 Score: 408.297 bits (1048), Expect = 3.180e-119 Identity = 320/1104 (28.99%), Postives = 515/1104 (46.65%), Query Frame = 0
Query: 251 DFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCR-------DDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQ-EECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGK--IRSLDDLHQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLS-GKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLT-VNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIID-KVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETD---DFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIK-NDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKG--QSSSVVLYVM-----VPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPD--KISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
+ + LENC+++EGHL I + R LSFP+L ++TD+ +++ ESL LFPNL VIRG L + YA V+ +L ++ L +L +LRG VR+E N LC++ TI+W ++ + G HI N+ C+D C + C H R CWT + + V PC G+ C RG E C ECLGGC P C +C+H +Q C CP + W C+ + C + S+ ++ T + I+ SC+ CP G + + + C KCE CPK C G I S+ CTH++G L +NL G ++ L+ +LG ++ VSL FF++L+ I G + Y+L +L+N+N+Q L S+ + G + GK + +NP+LC + I + + + +KA+I+ TNGD+A C L +++T + + + ++ Y+ + + R LL + ++Y+ E+ + +N T+ G DACG W ++D ++P E G V ++ L+P+T YA++V + + + + QGAQS I+Y++TL + P+ S S + + W+PP + NG +T+Y + + + + + + YC ++ SN D D D + S+ C C ++ E E F + + N I S +S N S Q+ S R +R+ G +L + D + +E V + GL+HF YR+ + AC+ + CS VF + AD I G+ + SS + V L W P DPN LI+ Y IK +E+T + C++ + K L PG Y V+A S+ G G W++ + G + + L+V+ V L + +LAA L +FY KK + + + S NP Y S + +Y DEWEVPR + ++ ELG G FGMV++G+ G + + S P A+KTV + A+ E I FL EA+VMK+
Sbjct: 41 ELRQLENCSVVEGHLQILLMFTATGEDF-RGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEMPHLRDVALPALGAVLRGAVRVEKNQELCHLSTIDWGLLQP-APGANHIVGNKLGEECADVCPGVLGAAGEPCAKTTFSGHTDYR-CWTSSHCQRVC---PCPHGMACT-----ARG--ECCHTECLGGCSQPEDPRACVACRHLYFQ----GACLWACPPGTYQYESWRCVTAERC------ASLHSVPGRAST----FGIHQGSCLAQCPSGF----TRNSSSIFCHKCEGLCPKECKVGTKTIDSIQAAQDLVGCTHVEGSLILNLRQGYNLEPQLQHSLGLVETITGFLKIKHSFALVSLGFFKNLKLIRGDAM--VDGNYTLYVLDNQNLQQLGSW----------------------VAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRAACQTRTLRFVSNVTEADRILLRWERYEPL--------EARDLLSFIVYYK---ESPF--QNATEHVGPDACGTQSWNLLDVELPLSRTQEPG--------VTLASLKPWTQYAVFVRAITLTTEEDSPH-QGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPTQRNGNLTYY-LVLWQRLAEDGDLYLNDYCHRGLRLP------TSNNDPRFDGEDGDPEAEMESDC--CPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPISPWKVTSINKSPQRDSG--RHRRA--AGPLRLGGNSSDFEIQEDKVPR-------ERAVLSGLRHFTEYRIDIHACNHAAHTVG----CSAATFVFARTMPHREADGIPGK--VAWEASSKNSVLLRWLEPPDPNGLILKYEIKYRRLGEEAT-VLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGSWTDSVAFYILGPEEEDAGGLHVLLTATPVGLTLLIVLAA---LGFFYGKKRNRT-LYASVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKA 1036
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|12644455|sp|Q60751.3|IGF1R_MOUSE (RecName: Full=Insulin-like growth factor 1 receptor; AltName: Full=Insulin-like growth factor I receptor; Short=IGF-I receptor; AltName: CD_antigen=CD221; Contains: RecName: Full=Insulin-like growth factor 1 receptor alpha chain; Contains: RecName: Full=Insulin-like growth factor 1 receptor beta chain; Flags: Precursor) HSP 1 Score: 408.683 bits (1049), Expect = 7.614e-119 Identity = 340/1155 (29.44%), Postives = 538/1155 (46.58%), Query Frame = 0
Query: 215 SLSGIANFLLLLLMIIPIQSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCR---DDCPLLK----NHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGK-----IRSLDDLHQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIID-KVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREY-----------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIK-NDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSS---VVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEIN-----ISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIG--PDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
SL G+ FL L + P EICG I I D Q+ K LENCT+IEG L I I++ E R FPKL IT++ +++ ESL LFPNLTVIRG L NYA V+ NL +IGL +L +I RG +RIE N LCY+ TI+W +I+ +I N+ C D C ++ P+ + N+ CWT +++ ++ + C + N E C ECLG C+ P C +C+H+ + K C CP F W C+D C + I N +S + I++D C++ CP G T+ + C CE CPKVC + I S+ + CT + G+L IN+ G +I LE+ +G I+ VSL F ++LR I G E YS +L+N+N+Q L+ D N +T + SGK + +NPKLC +I M + + K DI+ NG++A C L +++ T + N I + + D R L+ + ++Y+ EA + KN+T++DG+DACG + W ++D +P + E G +L+ L+P+T YA+YV + + + N H I+GA+S+ILYI+T S PS ++ S SS ++I W PP PNG +++Y + R+ D + YC ++ Y D + ++ +N KT + C C P+ + E + + + + V F NSI P R++R + ++ + + + R + V + E+ + L+ F YR+ + +C+ + + + CS VF + GADDI G P+ + I +L W P++PN LI+ Y IK S+ ++ C++ E+ K + + PG Y +QA S+ G G W++ + V +++ + L + +P+ + I+ V + Y +++K ++S + S NP Y S VY DEWEV R + + ELG G FGMV++G+ G D+ A+KTV + A+ E I FL EA+VMK
Sbjct: 12 SLWGLV-FLSAALSLWPTSGEICG-PGIDIRNDYQQ-LKRLENCTVIEGFLHILLISKAEDY---RSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNN-YIVGNKPPKECGDLCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRA--CTENN-------ECCHPECLGSCHTPDDNTTCVACRHYYY----KGVCVPACPPGTYRFEGWRCVDRDFC---ANIPNAESSDSDG------FVIHDDECMQECPSG---FIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEE--QLEGNYSFYVLDNQNLQQLW-------------------DWNHRNLTVR--SGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLRFTSTTT-------WKNRIIITWHRYRPPDYRDLISFTVYYK---EAPF--KNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPG--------ILLHGLKPWTQYAVYVKAVTLTMVENDH-IRGAKSEILYIRTNASVPSI--PLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQD-GYLYRHNYCSKDKIPIRKYADGTIDVEEVTEN---PKTEVCGGDKGPC----CACPKTEAEKQAEKEEAEYRKVFEN-FLHNSIFVPRPE-----------RRRRDVM----QVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLG----CSASNFVFARTMPAEGADDIPG-PVTWEPRPENSI-FLKWPEPENPNGLILMYEIKYGSQVEDQRE--CVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMK 1056
BLAST of EMLSAG00000002641 vs. SwissProt
Match: gi|2827762|sp|P24062.2|IGF1R_RAT (RecName: Full=Insulin-like growth factor 1 receptor; AltName: Full=Insulin-like growth factor I receptor; Short=IGF-I receptor; AltName: CD_antigen=CD221; Contains: RecName: Full=Insulin-like growth factor 1 receptor alpha chain; Contains: RecName: Full=Insulin-like growth factor 1 receptor beta chain; Flags: Precursor) HSP 1 Score: 406.757 bits (1044), Expect = 3.452e-118 Identity = 339/1155 (29.35%), Postives = 537/1155 (46.49%), Query Frame = 0
Query: 215 SLSGIANFLLLLLMIIPIQSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCR---DDCPLLK----NHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGK-----IRSLDDLHQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIID-KVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREY-----------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIK-NDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSS---VVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEIN-----ISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIG--PDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
SL G+ FL L + P EICG I I D Q+ K LENCT+IEG L I I++ E R FPKL IT++ +++ ESL LFPNLTVIRG L NYA V+ NL +IGL +L +I RG +RIE N LCY+ TI+W +I+ +I N+ C D C ++ P+ + N+ CWT +++ ++ + C + N E C ECLG C+ P C +C+H+ + K C CP F W C+D C + I N +S + I++ C++ CP G T+ + C CE CPKVC + I S+ + CT + G+L IN+ G +I LE+ +G I+ VSL F ++LR I G E YS +L+N+N+Q L+ D N +T + SGK + +NPKLC +I M + + K DI+ NG++A C L +++ T + N I + + D R L+ + ++Y+ EA + KN+T++DG+DACG + W ++D +P + E G +L+ L+P+T YA+YV + + + N H I+GA+S+ILYI+T S PS ++ S SS ++I W PP PNG +++Y + R+ D + YC ++ Y D + ++ +N KT + C C P+ + E + + + + V F NSI P R++R + ++ + + + R + V + E+ + L+ F YR+ + +C+ + + + CS VF + GADDI G P+ + I +L W P++PN LI+ Y IK S+ ++ C++ E+ K + + PG Y +QA S+ G G W++ + V +++ + L + +P+ + I+ V + Y +++K ++S + S NP Y S VY DEWEV R + + ELG G FGMV++G+ G D+ A+KTV + A+ E I FL EA+VMK
Sbjct: 12 SLWGLV-FLSAALSLWPTSGEICG-PGIDIRNDYQQ-LKRLENCTVIEGFLHILLISKAEDY---RSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNN-YIVGNKPPKECGDLCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRA--CTENN-------ECCHPECLGSCHTPDDNTTCVACRHYYY----KGVCVPACPPGTYRFEGWRCVDRDFC---ANIPNAESSDSDG------FVIHDGECMQECPSG---FIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEE--QLEGNYSFYVLDNQNLQQLW-------------------DWNHRNLTVR--SGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLRFTSTTT-------WKNRIIITWHRYRPPDYRDLISFTVYYK---EAPF--KNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPG--------ILLHGLKPWTQYAVYVKAVTLTMVENDH-IRGAKSEILYIRTNASVPSI--PLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQD-GYLFRHNYCSKDKIPIRKYADGTIDVEEVTEN---PKTEVCGGDKGPC----CACPKTEAEKQAEKEEAEYRKVFEN-FLHNSIFVPRPE-----------RRRRDVL----QVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLG----CSASNFVFARTMPAEGADDIPG-PVTWEPRPENSI-FLKWPEPENPNGLILMYEIKYGSQVEDQRE--CVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMK 1056
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: NP_001233596.1 (insulin-like receptor-like [Apis mellifera]) HSP 1 Score: 452.595 bits (1163), Expect = 5.928e-133 Identity = 353/1108 (31.86%), Postives = 520/1108 (46.93%), Query Frame = 0
Query: 250 RDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLD-------ESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNL-------DSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGG-GQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVS---HNSSSDIVWLSWNPPQDPNELIVNYNI---KIESKSKESTGIYCITAYEFIKNDYRY---HLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHD------DSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
R F L+ C ++EG + I I EPS + +SFP+LREIT + ++Y S+ LFPNLTVIRG L +NYA V NL EIGL SLT I+RG VR E N LCYV TI+WD+I +G I N +N C C CP CW + + + CE GN C CLG C GP+ +C CK + D+ CR CP+ L F + CID C + EK + Y+ +N SC+ CP G + ++ ++C+KCE C K C G + S+ + + CTHI G L I + GK+IV LE L I+ +SL+F ++LR I G + + Y+L +++N+N+Q L+ + +I + K ++G GK F H NPKLC KI EM++E + +++ +NGDK C N++ T G + I +E +D R+LL Y +++ EA +N+T +DGRDACGGD WK+ D S N +D + +SQL+PYT YA YV T I GAQS++ Y +T+ PS S S + + W PPL NG +THY + E D N I +R YC+E + DK P L ++ ++ C+C + + E E S DF D + N ++ P D L RK +SL +K+N + +F +N V + R ++ + L+HF +Y + ++AC + N D +CS + + AD+I +S N+S +V L W+ P PN LI+ Y I +++ ++ + T + CIT +F K Y LP G Y V V+A S+ G G ++ + ++ +++ +++ L+F +L AA++L FY K + + + NP Y+S + Y DEWEVPR +E+L LG G FGMV++GI I K CAVKTV K AT E I FL EA+VMK
Sbjct: 207 RQFSRLKGCRLVEGFVQILLIDNAEPSEYT-NISFPELREITGYLLLYRVKGLRSIGRLFPNLTVIRGHSLFINYALVAFEMMNLQEIGLHSLTTIVRGSVRFEKNPALCYVDTIDWDLIAKAGKGEHVISGNNPKNACP-VCEKHCPQRLTKQDEYLCWNQQHCQRIC-DRKCENNACDEAGN--------CCHSSCLGTCSGPTNRDCTVCKDVVTGDSE---CRERCPNGSLEFMNHRCIDEARC-----LQMEKPKEVLKNVKNYPYKPFNGSCVMECPPG--YMDDESNGRVSCKKCEGSCQKECAGANVDSIASAQKLRGCTHITGSLEIQIRGGKNIVKELEDGLSTIEEIDGYLKIVRSFPLISLNFLKNLRVIRGNDIDNSK--YTLLVMDNQNLQELWDWSLHKEISI--------KSKDG--------PGKIFFHLNPKLCLYKI-EMLREKAGLGPFTDYEVAPNSNGDKVAC-----NVTELKTRVGKKSPWGAV--IEWEPFVHHDARSLLGYVVYF---IEAP--NRNVTMYDGRDACGGDGWKVDD------VSASTNSTLMDSRQEKSVHTHYLSQLKPYTQYAYYVKTYTIAT-----ERSGAQSNLTYFRTMPEAPSSPRSLLTWSNSSSELIMSWLPPLHNNGNLTHYRIVGRWEPDDPNFIDQRNYCEEPMML----------TDKKPITLAEEERKRMEEEKEQMVPETGTCECADRETDQSLREKEASSAIDFEDALHNQVYVKRK---PRRKRDVSDI---LFRKTKSLDQPVMKKVNGTYV------AFEEN--VPSTNRSFVMKDLRHFAAYNIEVQACRAQEMN-DTYKKCSTKSMRTFRTMSLDSADNIPPNTFKMSISGENNSLTMVTLQWDEPPQPNGLIITYQIEYKRVDIQNYKPT-VVCITRRDFTKAGNSYVLKELPA-GNYSVKVRATSLAGNGAYTHVKYFYIEERNTMNTFWIVFWLLFCAVL-AALSLVAFYACKRKFLRNVPNVTLIATVNPEYVS--TPYVLDEWEVPREKIEMLRSLGTGTFGMVYEGIAKDIVKGKSEVRCAVKTVNKDATDRERIEFLNEASVMK 1221
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: XP_006568758.1 (PREDICTED: insulin-like receptor-like isoform X2 [Apis mellifera]) HSP 1 Score: 451.055 bits (1159), Expect = 2.789e-132 Identity = 353/1123 (31.43%), Postives = 518/1123 (46.13%), Query Frame = 0
Query: 250 RDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLD-------ESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNL-------DSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSL----------FGGGQKLNDLNIDVKKRESFVQNAIVA------GSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVS---HNSSSDIVWLSWNPPQDPNELIVNYNI---KIESKSKESTGIYCITAYEFIKNDYRY---HLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHD------DSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
R F L+ C ++EG + I I EPS + +SFP+LREIT + ++Y S+ LFPNLTVIRG L +NYA V NL EIGL SLT I+RG VR E N LCYV TI+WD+I +G I N +N C C CP CW + + + CE GN C CLG C GP+ +C CK + D+ CR CP+ L F + CID C + EK + Y+ +N SC+ CP G + ++ ++C+KCE C K C G + S+ + + CTHI G L I + GK+IV LE L I+ +SL+F ++LR I G + + Y+L +++N+N+Q L+ + +I + K ++G GK F H NPKLC KI EM++E + +++ +NGDK C N++ T G + I +E +D R+LL Y +++ EA +N+T +DGRDACGGD WK+ D S N +D + +SQL+PYT YA YV T I GAQS++ Y +T+ PS S S + + W PPL NG +THY + E D N I +R YC+E + DK P L ++ ++ C+C + + E E S DF D + N ++ P D L RK +SL F L + + + V VA + R ++ + L+HF +Y + ++AC + N D +CS + + AD+I +S N+S +V L W+ P PN LI+ Y I +++ ++ + T + CIT +F K Y LP G Y V V+A S+ G G ++ + ++ +++ +++ L+F +L AA++L FY K + + + NP Y+S + Y DEWEVPR +E+L LG G FGMV++GI I K CAVKTV K AT E I FL EA+VMK
Sbjct: 207 RQFSRLKGCRLVEGFVQILLIDNAEPSEYT-NISFPELREITGYLLLYRVKGLRSIGRLFPNLTVIRGHSLFINYALVAFEMMNLQEIGLHSLTTIVRGSVRFEKNPALCYVDTIDWDLIAKAGKGEHVISGNNPKNACP-VCEKHCPQRLTKQDEYLCWNQQHCQRIC-DRKCENNACDEAGN--------CCHSSCLGTCSGPTNRDCTVCKDVVTGDSE---CRERCPNGSLEFMNHRCIDEARC-----LQMEKPKEVLKNVKNYPYKPFNGSCVMECPPG--YMDDESNGRVSCKKCEGSCQKECAGANVDSIASAQKLRGCTHITGSLEIQIRGGKNIVKELEDGLSTIEEIDGYLKIVRSFPLISLNFLKNLRVIRGNDIDNSK--YTLLVMDNQNLQELWDWSLHKEISI--------KSKDG--------PGKIFFHLNPKLCLYKI-EMLREKAGLGPFTDYEVAPNSNGDKVAC-----NVTELKTRVGKKSPWGAV--IEWEPFVHHDARSLLGYVVYF---IEAP--NRNVTMYDGRDACGGDGWKVDD------VSASTNSTLMDSRQEKSVHTHYLSQLKPYTQYAYYVKTYTIAT-----ERSGAQSNLTYFRTMPEAPSSPRSLLTWSNSSSELIMSWLPPLHNNGNLTHYRIVGRWEPDDPNFIDQRNYCEEPMML----------TDKKPITLAEEERKRMEEEKEQMVPETGTCECADRETDQSLREKEASSAIDFEDALHNQVYVKRK---PRRKRDVSDI---LFRKTKSLDQVIDRSFLRFSRSASLTRMRVYWQPVMKKVNGTYVAFEENVPSTNRSFVMKDLRHFAAYNIEVQACRAQEMN-DTYKKCSTKSMRTFRTMSLDSADNIPPNTFKMSISGENNSLTMVTLQWDEPPQPNGLIITYQIEYKRVDIQNYKPT-VVCITRRDFTKAGNSYVLKELPA-GNYSVKVRATSLAGNGAYTHVKYFYIEERNTMNTFWIVFWLLFCAVL-AALSLVAFYACKRKFLRNVPNVTLIATVNPEYVS--TPYVLDEWEVPREKIEMLRSLGTGTFGMVYEGIAKDIVKGKSEVRCAVKTVNKDATDRERIEFLNEASVMK 1244
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: XP_006568757.1 (PREDICTED: insulin-like receptor-like isoform X2 [Apis mellifera]) HSP 1 Score: 451.055 bits (1159), Expect = 2.789e-132 Identity = 353/1123 (31.43%), Postives = 518/1123 (46.13%), Query Frame = 0
Query: 250 RDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLD-------ESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNL-------DSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSL----------FGGGQKLNDLNIDVKKRESFVQNAIVA------GSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVS---HNSSSDIVWLSWNPPQDPNELIVNYNI---KIESKSKESTGIYCITAYEFIKNDYRY---HLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHD------DSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
R F L+ C ++EG + I I EPS + +SFP+LREIT + ++Y S+ LFPNLTVIRG L +NYA V NL EIGL SLT I+RG VR E N LCYV TI+WD+I +G I N +N C C CP CW + + + CE GN C CLG C GP+ +C CK + D+ CR CP+ L F + CID C + EK + Y+ +N SC+ CP G + ++ ++C+KCE C K C G + S+ + + CTHI G L I + GK+IV LE L I+ +SL+F ++LR I G + + Y+L +++N+N+Q L+ + +I + K ++G GK F H NPKLC KI EM++E + +++ +NGDK C N++ T G + I +E +D R+LL Y +++ EA +N+T +DGRDACGGD WK+ D S N +D + +SQL+PYT YA YV T I GAQS++ Y +T+ PS S S + + W PPL NG +THY + E D N I +R YC+E + DK P L ++ ++ C+C + + E E S DF D + N ++ P D L RK +SL F L + + + V VA + R ++ + L+HF +Y + ++AC + N D +CS + + AD+I +S N+S +V L W+ P PN LI+ Y I +++ ++ + T + CIT +F K Y LP G Y V V+A S+ G G ++ + ++ +++ +++ L+F +L AA++L FY K + + + NP Y+S + Y DEWEVPR +E+L LG G FGMV++GI I K CAVKTV K AT E I FL EA+VMK
Sbjct: 207 RQFSRLKGCRLVEGFVQILLIDNAEPSEYT-NISFPELREITGYLLLYRVKGLRSIGRLFPNLTVIRGHSLFINYALVAFEMMNLQEIGLHSLTTIVRGSVRFEKNPALCYVDTIDWDLIAKAGKGEHVISGNNPKNACP-VCEKHCPQRLTKQDEYLCWNQQHCQRIC-DRKCENNACDEAGN--------CCHSSCLGTCSGPTNRDCTVCKDVVTGDSE---CRERCPNGSLEFMNHRCIDEARC-----LQMEKPKEVLKNVKNYPYKPFNGSCVMECPPG--YMDDESNGRVSCKKCEGSCQKECAGANVDSIASAQKLRGCTHITGSLEIQIRGGKNIVKELEDGLSTIEEIDGYLKIVRSFPLISLNFLKNLRVIRGNDIDNSK--YTLLVMDNQNLQELWDWSLHKEISI--------KSKDG--------PGKIFFHLNPKLCLYKI-EMLREKAGLGPFTDYEVAPNSNGDKVAC-----NVTELKTRVGKKSPWGAV--IEWEPFVHHDARSLLGYVVYF---IEAP--NRNVTMYDGRDACGGDGWKVDD------VSASTNSTLMDSRQEKSVHTHYLSQLKPYTQYAYYVKTYTIAT-----ERSGAQSNLTYFRTMPEAPSSPRSLLTWSNSSSELIMSWLPPLHNNGNLTHYRIVGRWEPDDPNFIDQRNYCEEPMML----------TDKKPITLAEEERKRMEEEKEQMVPETGTCECADRETDQSLREKEASSAIDFEDALHNQVYVKRK---PRRKRDVSDI---LFRKTKSLDQVIDRSFLRFSRSASLTRMRVYWQPVMKKVNGTYVAFEENVPSTNRSFVMKDLRHFAAYNIEVQACRAQEMN-DTYKKCSTKSMRTFRTMSLDSADNIPPNTFKMSISGENNSLTMVTLQWDEPPQPNGLIITYQIEYKRVDIQNYKPT-VVCITRRDFTKAGNSYVLKELPA-GNYSVKVRATSLAGNGAYTHVKYFYIEERNTMNTFWIVFWLLFCAVL-AALSLVAFYACKRKFLRNVPNVTLIATVNPEYVS--TPYVLDEWEVPREKIEMLRSLGTGTFGMVYEGIAKDIVKGKSEVRCAVKTVNKDATDRERIEFLNEASVMK 1244
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: XP_016773490.1 (PREDICTED: insulin-like receptor-like isoform X1 [Apis mellifera]) HSP 1 Score: 433.335 bits (1113), Expect = 4.586e-126 Identity = 352/1130 (31.15%), Postives = 519/1130 (45.93%), Query Frame = 0
Query: 250 RDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFI----------------------MYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLD-------ESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNL-------DSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGG-GQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVS---HNSSSDIVWLSWNPPQDPNELIVNYNI---KIESKSKESTGIYCITAYEFIKNDYRY---HLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHD------DSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
R F L+ C ++EG + I I EPS + +SFP+LREIT + + + S+ LFPNLTVIRG L +NYA V NL EIGL SLT I+RG VR E N LCYV TI+WD+I +G I N +N C C CP CW + + + CE GN C CLG C GP+ +C CK + D+ CR CP+ L F + CID C + EK + Y+ +N SC+ CP G + ++ ++C+KCE C K C G + S+ + + CTHI G L I + GK+IV LE L I+ +SL+F ++LR I G + + Y+L +++N+N+Q L+ + +I + K ++G GK F H NPKLC KI EM++E + +++ +NGDK C N++ T G + I +E +D R+LL Y +++ EA +N+T +DGRDACGGD WK+ D S N +D + +SQL+PYT YA YV T I GAQS++ Y +T+ PS S S + + W PPL NG +THY + E D N I +R YC+E + DK P L ++ ++ C+C + + E E S DF D + N ++ P D L RK +SL +K+N + +F +N V + R ++ + L+HF +Y + ++AC + N D +CS + + AD+I +S N+S +V L W+ P PN LI+ Y I +++ ++ + T + CIT +F K Y LP G Y V V+A S+ G G ++ + ++ +++ +++ L+F +L AA++L FY K + + + NP Y+S + Y DEWEVPR +E+L LG G FGMV++GI I K CAVKTV K AT E I FL EA+VMK
Sbjct: 207 RQFSRLKGCRLVEGFVQILLIDNAEPSEYT-NISFPELREITGYLLLYSRLLPLLPLSFTALPSLSVSVLRVKGLRSIGRLFPNLTVIRGHSLFINYALVAFEMMNLQEIGLHSLTTIVRGSVRFEKNPALCYVDTIDWDLIAKAGKGEHVISGNNPKNACP-VCEKHCPQRLTKQDEYLCWNQQHCQRIC-DRKCENNACDEAGN--------CCHSSCLGTCSGPTNRDCTVCKDVVTGDSE---CRERCPNGSLEFMNHRCIDEARC-----LQMEKPKEVLKNVKNYPYKPFNGSCVMECPPG--YMDDESNGRVSCKKCEGSCQKECAGANVDSIASAQKLRGCTHITGSLEIQIRGGKNIVKELEDGLSTIEEIDGYLKIVRSFPLISLNFLKNLRVIRGNDIDNSK--YTLLVMDNQNLQELWDWSLHKEISI--------KSKDG--------PGKIFFHLNPKLCLYKI-EMLREKAGLGPFTDYEVAPNSNGDKVAC-----NVTELKTRVGKKSPWGAV--IEWEPFVHHDARSLLGYVVYF---IEAP--NRNVTMYDGRDACGGDGWKVDD------VSASTNSTLMDSRQEKSVHTHYLSQLKPYTQYAYYVKTYTIAT-----ERSGAQSNLTYFRTMPEAPSSPRSLLTWSNSSSELIMSWLPPLHNNGNLTHYRIVGRWEPDDPNFIDQRNYCEEPMML----------TDKKPITLAEEERKRMEEEKEQMVPETGTCECADRETDQSLREKEASSAIDFEDALHNQVYVKRK---PRRKRDVSDI---LFRKTKSLDQPVMKKVNGTYV------AFEEN--VPSTNRSFVMKDLRHFAAYNIEVQACRAQEMN-DTYKKCSTKSMRTFRTMSLDSADNIPPNTFKMSISGENNSLTMVTLQWDEPPQPNGLIITYQIEYKRVDIQNYKPT-VVCITRRDFTKAGNSYVLKELPA-GNYSVKVRATSLAGNGAYTHVKYFYIEERNTMNTFWIVFWLLFCAVL-AALSLVAFYACKRKFLRNVPNVTLIATVNPEYVS--TPYVLDEWEVPREKIEMLRSLGTGTFGMVYEGIAKDIVKGKSEVRCAVKTVNKDATDRERIEFLNEASVMK 1243
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: XP_016773491.1 (PREDICTED: insulin-like receptor-like isoform X3 [Apis mellifera]) HSP 1 Score: 431.795 bits (1109), Expect = 6.047e-126 Identity = 351/1130 (31.06%), Postives = 519/1130 (45.93%), Query Frame = 0
Query: 250 RDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFI----------------------MYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLD-------ESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNL-------DSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGG-GQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVS---HNSSSDIVWLSWNPPQDPNELIVNYNI---KIESKSKESTGIYCITAYEFIKNDYRY---HLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHD------DSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
R F L+ C ++EG + I I EPS + +SFP+LREIT + + + S+ LFPNLTVIRG L +NYA V NL EIGL SLT I+RG VR E N LCYV TI+WD+I +G I N +N C C CP CW + + + CE GN C CLG C GP+ +C CK + D+ CR CP+ L F + CID C + EK + Y+ +N SC+ CP G + ++ ++C+KCE C K C G + S+ + + CTHI G L I + GK+IV LE L I+ +SL+F ++LR I G + + Y+L +++N+N+Q L+ + +I + K ++G GK F H NPKLC KI EM++E + +++ +NGDK C N++ T G + I +E +D R+LL Y +++ EA +N+T +DGRDACGGD WK+ D S N +D + +SQL+PYT YA YV T I GAQS++ Y +T+ PS S S + + W PPL NG +THY + E D N I +R YC+E + DK P L ++ ++ C+C + + E E S DF D + N ++ +D L RK +SL +K+N + +F +N V + R ++ + L+HF +Y + ++AC + N D +CS + + AD+I +S N+S +V L W+ P PN LI+ Y I +++ ++ + T + CIT +F K Y LP G Y V V+A S+ G G ++ + ++ +++ +++ L+F +L AA++L FY K + + + NP Y+S + Y DEWEVPR +E+L LG G FGMV++GI I K CAVKTV K AT E I FL EA+VMK
Sbjct: 207 RQFSRLKGCRLVEGFVQILLIDNAEPSEYT-NISFPELREITGYLLLYSRLLPLLPLSFTALPSLSVSVLRVKGLRSIGRLFPNLTVIRGHSLFINYALVAFEMMNLQEIGLHSLTTIVRGSVRFEKNPALCYVDTIDWDLIAKAGKGEHVISGNNPKNACP-VCEKHCPQRLTKQDEYLCWNQQHCQRICDR-KCENNACDEAGN--------CCHSSCLGTCSGPTNRDCTVCKDVVTGDSE---CRERCPNGSLEFMNHRCIDEARC-----LQMEKPKEVLKNVKNYPYKPFNGSCVMECPPG--YMDDESNGRVSCKKCEGSCQKECAGANVDSIASAQKLRGCTHITGSLEIQIRGGKNIVKELEDGLSTIEEIDGYLKIVRSFPLISLNFLKNLRVIRGNDIDNSK--YTLLVMDNQNLQELWDWSLHKEISI--------KSKDG--------PGKIFFHLNPKLCLYKI-EMLREKAGLGPFTDYEVAPNSNGDKVAC-----NVTELKTRVGKKSPWGAV--IEWEPFVHHDARSLLGYVVYF---IEAP--NRNVTMYDGRDACGGDGWKVDD------VSASTNSTLMDSRQEKSVHTHYLSQLKPYTQYAYYVKTYTIAT-----ERSGAQSNLTYFRTMPEAPSSPRSLLTWSNSSSELIMSWLPPLHNNGNLTHYRIVGRWEPDDPNFIDQRNYCEEPMML----------TDKKPITLAEEERKRMEEEKEQMVPETGTCECADRETDQSLREKEASSAIDFEDALHNQVYVKRKPRRKRDVSDI------LFRKTKSLDQPVMKKVNGTYV------AFEEN--VPSTNRSFVMKDLRHFAAYNIEVQACRAQEMN-DTYKKCSTKSMRTFRTMSLDSADNIPPNTFKMSISGENNSLTMVTLQWDEPPQPNGLIITYQIEYKRVDIQNYKPT-VVCITRRDFTKAGNSYVLKELPA-GNYSVKVRATSLAGNGAYTHVKYFYIEERNTMNTFWIVFWLLFCAVL-AALSLVAFYACKRKFLRNVPNVTLIATVNPEYVS--TPYVLDEWEVPREKIEMLRSLGTGTFGMVYEGIAKDIVKGKSEVRCAVKTVNKDATDRERIEFLNEASVMK 1243
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: gb|EFA11583.2| (insulin-like receptor [Tribolium castaneum]) HSP 1 Score: 404.06 bits (1037), Expect = 1.941e-117 Identity = 343/1140 (30.09%), Postives = 530/1140 (46.49%), Query Frame = 0
Query: 233 QSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIV-----------------------------VGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLIG-KSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMC-----KAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQ-NAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKN-IDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNI---KIESKSKESTGIYCITAYEFIKNDYRYHLPV--PGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINI--SSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGI---FIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
+ EIC + I+ D F L+ C ++EG + I V + LS LSFP L EITD+ ++Y N S+ LFPNL+VIRG Y+FVV ++L EIGL SLT I RG +RI+ N LC+V++I+W+ I S IH + +R+ ++ RD HL CW + +++ P + +C ++E C + CLGGC + C CK+ +K C ++CP + + + CI EC++ +N ++ E ++I+N+SCI CP N + D C C+ C K C G + S++ Q K CTHI L I + G +++V+ LE +LG I+ VSL+F ++L+ I G SQ+ Y +L+N+N+Q L+++ EN T K +G+ F H+NPKLC ++I E ++ D + ++++ +NGDK C L + VN V + +E +D R LL Y IV +N+T +DGRDACGGD W++ D E + ++ + ++ L+PYT YA YV T I +GAQS I Y TL P+ E+ S +S+K+ W PP PNG +THY +++ R HN P E E + S++ K P + S V S T D C I + EKS D F D + N ++ + P+ S RK+R + N + + + +++ + +V G+ E+ L+H+ Y + ++AC E + +D + CS + K GADDIK + N S +V L+W P+ PN LI Y I K+E ++ ++ Y IT FI Y L PG Y V V A + + +S + ++ + S+ + ++V ++ + I+ A A ++ KK D + + S NP Y+ SVY DEWEVPR +EL+ ELG G FGMV++GI G +I CAVKTV + AT+ E + FL EA+VMK+
Sbjct: 57 EGEICESVDIRNTLD---SFNRLKGCHVVEGFVQILLFDNVNETELSL-LSFPNLTEITDYLLLYRVNGLRSIGQLFPNLSVIRGRSTFYTYSFVVFEMSSLQEIGLYSLTDITRGLIRIDKNPSLCFVNSIDWEAIAHEKGEHFIKNLKSPNECPICPGDEKEDESGNSVAHIHCHKAPHRSDSENFDRD------VHL----CWNRQHCQKIC---PTKCKHSC-------NANLECCDESCLGGCSINDTKLCTVCKNLSMGFGAKKQCMSSCPPDYYQYLERRCILKNECKDMKRPLN----FQQQGGPEKPFKIFNNSCILECP------PNYMSNDTHCIPCQGNCIKKCAGVNVDSINLARQLKGCTHITSSLEIQIRGGRNVVNELEESLGMIEEIDGYLKVVRSFPLVSLNFLKNLKVIHGRQLESQK--YVFVVLDNQNLQELWNW------------------ENNK--TLKIDTGRLFFHFNPKLCIREI-EKLQNITHIVDVTELEVAKNSNGDKIACELQVLKVDKPKVVNSKGVVLE------WEPFKIDDPRKLLGY-----IVYSIEAPTQNVTLYDGRDACGGDGWRVDDVAIPENE--------MNVTHPLTSLKPYTQYAFYVKTYTIAT-----ERRGAQSMISYFTTLPDTPTAPVGLEVVSNSSNSLKLSWRPPKSPNGKLTHYIVSLKR----HNSTT--PDLDE----MEHFCKSPSSRPKHP--IPSVSVPPVTSTTTSNDTCQCLETKPSTSSINEDVEKSRID-FEDELHNAVY----VRKPNFSES---------RKRRDVDSEQLNANRVFNETDEAGAYISFSTVVTGT--EFYMPNLRHYTVYEINVQACREKTNDKLDTENPCSSKNMKTHRTLKKKGADDIKQIEV---KNQSLGMVSLTWKEPEAPNGLIYCYTIEYKKLEIENSKANEEY-ITHARFINQSRIYTLKALSPGNYSVRVSATTSGDYANFSPYAYFYIEERPSNTYVTLIVCMLILVIILALCAFCFYKKKKADKESMRLIPSVNPEYVP--SVYVPDEWEVPRKKIELIRELGQGSFGMVYEGIAQDVRGKAQIK--CAVKTVNEHATNRERLEFLNEASVMKA 1079
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: gb|KFM70273.1| (Insulin-like peptide receptor, partial [Stegodyphus mimosarum]) HSP 1 Score: 387.882 bits (995), Expect = 3.339e-115 Identity = 296/976 (30.33%), Postives = 472/976 (48.36%), Query Frame = 0
Query: 251 DFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYC--RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEFCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLIGKS-IVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFS-FGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNIST-SLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDD-------FHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLF----GGGQKLN--DLNIDV-KKRESFVQNAIVAGSAREY----------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNI---KIESKSKESTGIYCITAYEFIKNDYRYHLP--VPGAYYVSVQAVSVYG 1176
+F+ LENCT+IEG+L I I + LSFP L EIT +F++Y A S+ +FPNL VIRG+ L NYAFVV L EIGL LT ILRG VRIE N LCYV T++WD+I +G +I N+ C + C D CP + + + CW +++ LTC Q N + C KECLGGC+G S +C C+H +++ C CP F C+ EC+ +Y +++ TE++ + + ++ + C + CP G I + + R + E CPKVC G + ++ + Y CT+I G L I + G S ++ LE N+ KI+ VSL+F +SL I G + +K Y+ +L+N+N+Q L+ K +R+ L+G+ F H+N KLCP KI+E+ K ++ + ++D D+S +NGD+ C +N++ SLT + + + +D++ K + +D R+LL Y I+YR EA Y +N+T F+GRDACG D W + D E ES ++ + ++ L+P+T YALY++T +GAQS I+Y +T PS + + + I W+PP +PNG +THY + E I +R YC E + DYK+ + ++ K +DS + + + C P + + E DD F D + N ++ N + + R+KR ++ LN +LN+ ++A + G+ ++ + LKHF Y + +RAC +D + D CS ++ + ADDIK + + N++S ++ W P+DPN +IV Y + ++ +SK+ I C+T +++ + Y LP PG Y + V+A S+ G
Sbjct: 52 NFQKLENCTVIEGYLQIILIDKGRTEDYD-GLSFPDLVEITGYFLLYRAFGMNSIGKIFPNLAVIRGNTLFHNYAFVVNEMYQLQEIGLSRLTDILRGSVRIEKNPGLCYVDTVDWDLIAKEGKGGHYISGNKKWEECPNTCPEPDLCPKTVRNDAKSINLCWNSHNCQKIC-------PLTCEQENSSCSDNFVCCHKECLGGCHGRSLSDCAVCRHVVYEGR----CLKKCPPGTFEFLGRRCVQEHECKNYTY---DENYTEQNNDKRVFWKAFMGQCREKCPPG--YIEDDKDRHVCKECVGKCPKVCEGSVVDNVGAIQNYYGCTYIKGSLEITIKGGSNVIRELEENMDKIEEIQGYLKVARSFPLVSLNFLKSLNTIHGENL--DKKDYAFLVLDNQNLQELWDPKNRKQPLRI--------------------LNGRIFFHFNSKLCPSKILELKKYAK-TLEWDDRDVSPSSNGDRIACDVINMNVTVYSLTPSMVKIKWDSFNKYL------DDERSLLGYVIYYR---EAPY--RNITMFEGRDACGTDIWTVRD---VEVSQESRKHIYHN----IANLKPFTQYALYISTY-----TTTSGRRGAQSSIVYFKTEPYTPSPPVNIKARSTLHGEIVISWKPPKRPNGDVTHYIVTGIYEEEPEEFINQRNYCLEP-RTFPDYKNSEEDELKYLTAMDSGNSSLGIDEVKDC------CPCAKTYSKLGEGDDDAEFQMHFEDFLQNQVYCKNPL---------------MFRRKRQIYFQDSANISALNSKELNLTAYNTSREIEEDAYLDGNLVQFKRYVNHNTFLVISNLKHFAEYTIKIRAC-QDTRPRKAIDNCSTKAIASVRTLHLAEADDIKAVHV-TTDNATSYSGFVRWEEPKDPNGVIVTYTLEYRRLNGESKKPNRI-CVTRTNYLERN-GYFLPELAPGNYSLRVRATSLAG 938
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: EFX85381.1 (putative insulin-like receptor [Daphnia pulex]) HSP 1 Score: 395.586 bits (1015), Expect = 9.439e-113 Identity = 333/1179 (28.24%), Postives = 530/1179 (44.95%), Query Frame = 0
Query: 233 QSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIH--IQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEK----------CSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDS--CIKGCPLGTQQITNKETRDL---TCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKIDV--------------SLDFFRSLRHIAG----IHYPSQEKY---YSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKES----QLSTDYDKADISEFTNGDKAICSHFKLNIS-TSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVP---SEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENY------KIKEDYKDEQSNKDK------------DPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETD-----DFHDIVLNTIFTSNSI---------STPSSSNDSGQKKSELLRKKRSL---------FGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDP-NDRCSDDLTVFL---KVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLP--VPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMKSERAN 1314
+ EIC + +++ + + F LE C ++EG L I + ++ ++ SFP LREIT + + Y S+ LFPNL VIRG L+ +++FVV L EIGL+SL + RG V IE N LCYV +I+W I G G ++ IQ N+ + C C+D CP + RR CW ++V C++ C QG G + + C +EC GGC G +C CKH + D CR+ CP +F C+ EC + + +S+ E ++ ++++ +S CI CP G Q+ L TC C+ CPKVC G + +++ + + + CT IDGDL + + G +I+ LE +LG I+V SL FF+SLR I G +H + + Y+LT+ +N+N+Q L+ P + L + K H+NPKLC I E++ S L+ + DIS ++NGDKA C LN++ + + + +S++N++ + D R LL Y I Y EA Y KN++ FD RDACGGD W ID +EP+ N +++ L+PYT YA+YV T + I GA+S ILY +T ++P + S S + I W+PP+ PNGI+THY + + D + + C E+ + K+ +E S ++ P+ ++ ++ + + C C + EK E + +F + + + I+ ++I T + D E K ++ G+ + + +F Q V G++ Y G++H+ Y + + ACH+ DP +R +T L + ADDI G + N++S + + WN P+DPN LI Y ++ C+ +F+++ + +PG Y V V+AVS+ G G ++ ++ + D +S NP Y Y DEWEV R++V +L ELG G FGMV++G+ P++ CA+KTV + A E + FL EA+VMK AN
Sbjct: 78 EKEICPSIEVR---NGPQQFSELEGCRVVEGFLHIVLMENLDFASDLNNRSFPALREITGYLLFYRVFGLRSIGQLFPNLAVIRGQQLLFDFSFVVYELMQLQEIGLKSLAELQRGSVLIEKNPNLCYVESIDWGRI--GHSGRLNHFIQGNKRASECPK-CQDRCPAGGD--GRRLCWNNDDCQKV-----CDQ---CGQGVSGACSVMTRDVGRPSEMRCCHEECAGGCSGGQSNQCDVCKHVIHNDE----CRSVCPPGHYLFMKRRCVTDVECI--TMLPPRQSVQEYPYVKK-NWKVFAESGECILECPPGFQEQKRHHNDTLHYFTCVPCQGPCPKVCKGLFVSNIETVQKLRGCTTIDGDLEMQIKGGDNIIQELERSLGSIEVIKGVLKITRSFPILSLSFFKSLRTITGKPETLHSSGSKNFDDEYALTVQDNQNLQQLW-----PKTQNLTIHK------------------KMLFHFNPKLCLNLIEELVNSSTVPGTLAFKHSDVDISPWSNGDKATCDEQVLNVTIVNKSDKSMQLSWNNFRATLA------DKRQLLGYVISYI---EAPY--KNVSYFDRRDACGGDGWTTIDVAANHDAEPEENEMN--------IITYLKPYTQYAIYVQTYTVAPQQTGKRI-GARSPILYERTSPAEPDQPEDLRASANSSSELVIDWKPPINPNGIVTHYIVTGSWRKDDQDYFDKLDTCAEHASSLVVSETKKPVLEETSPDNRTSIFGDPSIFAASPEGNNNPESGGSSGSAQQGKCCQCTGTNDKVTLEKKEKEQQFKIEFENFLHDKIYIKDTIVLGRKKRHVDTTTEIGDPDNNAIEFPEDKPTINSSHNQAIGIAPGENHTNFYDGNNRLITFYQK--VTGTS--YTVVGVRHYAEYTIKVIACHDH----DPFTNRTLCSMTAALTSARTKQSDFADDIVGGVVRYESNNTSRSIKIGWNEPEDPNGLIKKYLLEYRRSDNGKVVRECVRRKDFVESQRTKLMADLIPGNYCVQVRAVSLAGPGPPTKDVCFLIENK---------------------------------DDHGTVSINPDY----HKYVPDEWEVARDNVVILRELGQGSFGMVYEGLLRNTVPNQPEVKCAIKTVNEKANVKERMEFLTEASVMKEFNAN 1145 HSP 2 Score: 95.9005 bits (237), Expect = 8.645e-19 Identity = 74/272 (27.21%), Postives = 116/272 (42.65%), Query Frame = 0
Query: 1045 YIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLP--VPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKSERAN 1314
Y G++H+ Y + + ACH D + CS + ADDI G + NS++ + + W+ P+DPN LI Y ++ + CI +F++++ + +PG Y V +A S+ G G + K + D + +S NP Y Y D+WEV R++V + LG G FGMV++GI ++ CA+KTV + A E I FL EA+VMK A+
Sbjct: 1245 YTVVGVRHYAEYTIQVIACH-DHDPVRNRSLCSLTAVTSARTKQSDFADDIVGGVVRYDSNSTTSSIKIGWSEPEDPNGLITKYLLEYKRTDNGKVVRECIRRKDFVESNKTRLMADLIPGNYCVHARAFSLAGPGPPT---------------------------------------KDNKDGKGIVSINPDY----HRYVPDDWEVARDNVVTIRPLGQGSFGMVYEGILRSNGSETK-CAIKTVNEKADVTERIQFLNEASVMKEFNAH 1471
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: gb|KPM07669.1| (insulin receptor-like protein [Sarcoptes scabiei]) HSP 1 Score: 348.206 bits (892), Expect = 1.251e-100 Identity = 299/975 (30.67%), Postives = 451/975 (46.26%), Query Frame = 0
Query: 252 FKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLK---------NHLTRRACWTKATVKEVTFAIPCEE-GLTCYQGNDGTRGSIEKCSKECLGGCYG----PSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEFCPKVCPGGKIRSLDDLHQYKECTHIDGDLS--INLIGKSIVDGLESNLGKIDVSLDFFRSLRH--IAGIHYPSQEKYYSLTILE-NENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKE---SQLSTDYDKADISEFTNGDKAICSHFKLNIST-SLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYL---------------KKNLTQFDGRDACGGDYWKII--DKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDK------DPDNLDSKKTVSVLS--------NLTK--CDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNID------VKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILV-----SHNSSSDIVWLSWNPPQDPNELIVNYNIK----IESKSKESTGIYCITAYEFIKNDY 1155
FK L NCTIIEGHL I + + +A + FP LRE+TD+ + + +SLA +FPNL+VIRG L+ NYAFV+ +L EIGL++LT ILRG +RI+ N LC+V TI+W I S I N+++N+C + C ++CP++ + R CWT ++ CE TC N G+ C ++CLGGC P + C SCK++++ + C +CPS F D C+ EC + S T KY+ + C CP+G I + L E E CPK+C +I ++ Q K CT I+G L IN G IV LE NL + F + R + I++ + + ILE N N+Q L++F E LI +++ K L+GK F+H NPKLC KI MIK L +D+ D+S +NGDK C+ F LN+ +T L + +DN+ KI E D R+LL Y I+YR A +N+T FDG+DAC + W ++ D + + + V +++L+PYT YALY+ T I D A + GAQS+I+Y T PS+ + ++S+ + W+PP KPNG +T Y + ++ D +I+ R YC E + KE K + K +N D K+ + V + +L+K C C + +I+ + ++ +F D ++NT++ + + S + +ND + D K + N IV I E L+HF Y + ++ACH D N+ CS +K PGADDI R + + N+ V ++W P PN I++Y I+ E SK C T ++ +NDY
Sbjct: 82 FKKLANCTIIEGHLRIV-LIDNGIAADYENIQFPMLREVTDYVLFFRVMGLQSLAKMFPNLSVIRGRKLLHNYAFVIYEMLHLQEIGLKNLTSILRGDIRIQKNPNLCFVDTIDWSRIAQSS----LISDNKDQNLCPN-CPENCPIVSARSSNGKKIGDVFDRVCWTSDVCQKHACLDECESLNRTC--SNTGS-----CCPEQCLGGCIADPLNPIEHICISCKNYVYD----HRCFKSCPSDSYAFFDRRCLTENECNKLS-------------TVSKKYKAFMGECDYKCPVG--HIEDPSNPHLCLECGENCPKICESSQISNIAQAQQLKGCTVINGSLEIYINNQGAQIVKELEENLKDLVEITGFLKIARSFPLVTINFLKKLRIIRGQILEHNPNLQDLWTFKED---EFLINNEKRI----------KILNGKIFVHINPKLCFVKIRNMIKYVDIVDLKLPWDERDVSTHSNGDKVPCNVFDLNVEIKGITSEMLLIKFDNF-KIHME-----DPRSLLGYLIYYREAYVALIKFNFSILLISLNLFREHRNVTVFDGQDACSNNEWTVVEFDTMKDDDGQDYHEHV-------IAELKPYTQYALYIKTYTI-DTATK----GAQSEIIYFHTSPDVPSQPLNLFAKAEKHNSIYVKWDPPSKPNGEVTLYHVKASK---DELQIIHRDYCSETFTKKETVKPLVIQEPKINHWLQGINNTDFKQEIDVKTKSSSQTKQDLSKQCCSCRNDDSTKIK-PTDVEQSINFEDYLINTVYKRRKRQLNKTDEYLTTTPFSSIYPNISNYNYEFNINDTSHDNLTISSPKISRKWHYNGIVEKKLNVLI-ENLEHFTEYTIEVKACH------DANEFCSVTAITSVKTLPLPGADDIDERTMSYFIDNSTINNKFKFVHITWQEPPSPNGFIISYQIEYKRITEDHSKSIVAPSCFTRDQYERNDY 982
BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Match: EEB18223.1 (Insulin receptor precursor, putative [Pediculus humanus corporis]) HSP 1 Score: 345.51 bits (885), Expect = 9.171e-98 Identity = 312/1090 (28.62%), Postives = 483/1090 (44.31%), Query Frame = 0
Query: 278 LSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVV--GSEGFIHIQR--NENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLT-CYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETR---DLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSF-GEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKI---VEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLN--VSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDK-VPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNK------DKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEY-EKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACH---EDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIE--SKSKESTGIYCITAYEFIKNDYRY---HLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSS-------SVVLYVMVPLVFIFILAAAVALTYFYYKKHDDS--EINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
L ++FP+LRE+T + I + S TLFPNL+VIRG L NYA V+ L EIGL SLTHILRG VR + N+ LC+V TI+WD I E FI R E + CPL + CW K C++ C + +G E C + CLGGC G ++CY CK+ ++ KN C CP + D C+ EC + + ++ I +R D C CP + KET C C+ C K CPGG I S+ ++ CTHI G L I+L +IV L+ +L ++ +SLDF ++L+ I G + + + +L+NE ++ L+ + + D+R+ L+G+ IH+NPKLC KI VE++K + D ++ TNGDK C L+V G S+ N I FE+ D R LL Y ++++ KN+T + GR+ACGGD W +DK VP+ Q N + D + L+P+T YA ++ T I GA+S I Y T P+ S S V I WEPP + NG THY + + DH + R +C E I + ++ D ++ + V + + D ++ +QN + +S +H + + F +++ T N + ++L+K F G K++ SF + + L +F +Y++ ++AC E + + + +D + V + ++ N + + L W P +PN LI++Y I+ K + + CI +F++ Y HLP PG Y V V A S+ G G +S ++ + L + + FIFIL Y ++K+ ++ + NP Y+S ++Y DEWEVPR ++EL+ ELG G FGMV++GI I + CAVKTV + +T + + FL EA+VMK+
Sbjct: 12 LINNITFPELREVTGYVIFWRVQGLRSFGTLFPNLSVIRGKTLFHNYALVIYESKALQEIGLYSLTHILRGSVRFDENSNLCFVDTIDWDWIAPQGAKEHFIGDNRPIEECLKCPISVNNEKCPLSSS--GEPLCWNKEH---------CQKDFRDCVKDENG-----ECCHESCLGGCSGKLSKDCYVCKNVVF----KNDCTQECPENMYKYLDRRCVTESECFN---MTKPLDVEKRDIASPFPFRPILDMCTLECPANFSEY-EKETEYGLRFQCRPCDGPCKKECPGGSINSISSAQKFAGCTHIKGSLEIHLRFAGNIVTELQESLRSVEEISGYLKVARSLPLLSLDFLKNLKVIRGEELHNNKS--AFVLLDNERLEELWDWDAREKDLRI--------------------LNGRLAIHFNPKLCFYKIEKFVEIVKIKGFTED----EVPRGTNGDKEAC---------ELSVVGCCRLFSFPNKVVIRFEKFQHYDQRTLLGYVLYFKKAP-----NKNVTLYYGRNACGGDGW--MDKDVPAPKQDNHQNEISYD----LIGLKPFTQYAYFIKTYAISS-----ERSGARSGIQYFITNPGTPTSPRSLFAFSNSTSEVVISWEPPAEMNGNFTHYFVE-AEAMEDHPK--SRDFCSEPLVIATKKLEIPTSPPPAVKTSSDSCACEAPRKVDLKVSEAVRDSEIYFENALQNSFIVRSCYHHYHYFL--SFFRTDNKRTKREMNYAEGSHPQILQKNH-FFNEGVGGKSFGNTKKEKVSFTFEV----RTNKLVVRNLNYFTNYKIQVQACRAVVEGENGVHSPCKTADKIPVITLIP--------------LTSNGTVEETNLRWEEPPNPNGLILSYQIEYRRVDNDKYKSVVECIVREKFLEQKKEYVLKHLP-PGNYSVRVLASSLAGDGPYSSPLTFYIRQPPHPSTIDILGIGLGAICGIAFIFIL-------YMFWKRKTSGVPKLFANVNPEYVSAATIYVPDEWEVPRENIELIRELGQGSFGMVYEGIARDIVQGEPEVRCAVKTVNEVSTDRDRMEFLNEASVMKA 994
BLAST of EMLSAG00000002641 vs. nr
Match: gi|926638745|ref|XP_013785403.1| (PREDICTED: insulin receptor-like [Limulus polyphemus]) HSP 1 Score: 495.352 bits (1274), Expect = 7.876e-147 Identity = 374/1157 (32.32%), Postives = 564/1157 (48.75%), Query Frame = 0
Query: 229 IIPIQ-SEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPL--LKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYND--SCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINL-IGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGL-NVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQ-SNKDKDPDNL-------------DSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSN-------------SISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAI-----VAGSAREYIAEGLKHFGSYRVTLRACHE-DKKNIDP----NDRCSDDLTVFLKVSNKPGADDIKGRPILV-SHNSSSDIVWLSWNPPQDPNELIVNYNIK---IESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWV----TVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYK---KHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKG----IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
+I +Q E+C N I+ D FK LENCT++EG L I I + LSFPKLREIT + +Y A ES+ +FP LTVIRG+ L NYA V+ L EIGL SLT I+RG VRIE N LCYV++I+WD+I +G I+ N C C ++CPL LTRR CW ++V C E TC +G C KECLGGC G S +C SC++ ++ D C CPS W CID CR S + NE +E + TRE+ ++ + SC++ CP+G + + R C KC CPKVCPG + S+ + CT I+G L I + G ++++ LE NL I VSL+F ++LR I G + Q YSL + +N+N++ L+ +K N L + GK F H+NPKLCP++I E+ S + + +D+ D+S +NGD+ C+ L S + + + ++N+ +N D R+LL Y IHYR E KN+T FDGRDAC + WK+IDK ++ + ++ ++ L++ L+P+T YA Y+ T + A +GA+S+I Y T PS + +S ++I W+PP +PNG +THY + RE+ + I +R YC + I D+KD +D D NL D + N C C K E + E E + F D + NT++ N +I T + + S + +K F + + + E+ +N + + + L+H+ Y + +RAC + DK+ + + CS + ++ ADDI IL+ + NSSS + + W+ P++PN +IV+Y+++ +++ S + T + CIT ++ +R PG Y + +QA S+ G G W+ + T G ++ V+ V+ V FI+ + K + D + S NP Y+S +VY+ DEWEVPR+ V LL ELG G FGMV +G + G K+ CAVKTV + A+ E I FL EA+VMK+
Sbjct: 44 VIGLQPEEVCRNIDIRNSVD---QFKKLENCTVVEGFLRIVLIDNGTARSY-ETLSFPKLREITGYLFLYRAFGMESIGKVFPELTVIRGNLLFQNYALVIYEMFQLQEIGLSSLTDIVRGSVRIEKNPYLCYVNSIDWDLIAKAGQGGHFIKHNREPRDCPSVCPENCPLNTRNGPLTRRLCWNSHLCQKV-----CSE--TCQSSTCDHQGRC--CHKECLGGCNGISSSDCKSCRNVVYVDR----CLEKCPSLTYQHMGWRCIDENVCR--SMVTNEILGSEGN-TREIYWKPIDKLRSCMQDCPVGYVENSTDRHR---CIKCSGHCPKVCPGTVVDSVAAAQKLSGCTTINGSLIIQIHSGANVIEELEENLKYIQNITGFLKVFRSYPLVSLNFLKNLRDIHGEEFEKQN--YSLLVYDNQNLEDLW----------------DWKSRNYTL---RFRQGKIFFHFNPKLCPERITELKNYSTVRS-WDERDVSPSSNGDRVACNVTSLEASPWRVCSSMAGILWENF------RNKVGDHRSLLGYTIHYRKAKE-----KNITMFDGRDACEMNVWKVIDKEATDDKNKT--TIYH----LITHLEPFTQYAFYIQTYNLAQAA-----KGAKSEIKYFTTSPDTPSPPLNVHSQAISVGEIRIKWQPPKRPNGNVTHYIVKGKRELDSTDYIRQRDYCTQPIVI--DFKDRGIEEEDGDTTNLWVNSSHTGQGVDKDGSDEGGITKNGKCCPCTD-KKGEKKQEDEIQDQIQFEDAIHNTVYIKNPNARLGVSSRSRRAIYTSKNPQKVTESGSTSISEKNLHFSTTLEPGNTSTSHPPSENVTENGVYIRFSINVTHTSLTVSQLRHYTEYTIEVRACQDIDKETQNSSCHLHQPCSTEAIASIRTLPLSNADDIDSNTILIRTDNSSSKTMLIKWDEPKNPNGVIVSYSVEYTHLDNDSPKPT-VVCITHLQYQTDKGHRLTALSPGNYSLRLQATSLAGNGNWTNYVFFKIPETSGGLTTEVLALVVCCTVATFIIFGVGGWIFVRRKLAPRVPDGVLYASVNPEYMS--AVYEPDEWEVPRDKVCLLRELGQGSFGMVWEGEAKDLVEGKPKVK--CAVKTVNESASLRERIEFLQEASVMKA 1125
BLAST of EMLSAG00000002641 vs. nr
Match: gi|1009554515|ref|XP_015912635.1| (PREDICTED: insulin-like peptide receptor isoform X2 [Parasteatoda tepidariorum]) HSP 1 Score: 484.182 bits (1245), Expect = 4.129e-143 Identity = 350/1115 (31.39%), Postives = 552/1115 (49.51%), Query Frame = 0
Query: 252 FKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRD-DCPL---LKNHLTRRACWTKATVKEVTFAIPCE-EGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLG-TQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNIST-SLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESV--LVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYK--DEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETD-DFHDIVLNTIFTSN-SISTPSSSN-DSGQKKSELLRKKRSLFGGGQKLN-----DLNIDVKKRESFVQNAIVAGSARE-----------YIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIES--KSKESTGIYCITAYEFIKN-DYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTV----KGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD---SEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
F LENC+++EG + I I E ++FPKL+EIT + ++Y +SL+ LFPNLTVIRGD L NYA V+ + ++GL SLT ILRG VRIE N LCYV TI+WD+I I+ N+ C + C + DC + K H ++ CW ++V + CE + LTC + + C +ECLGGC G +EC +C+H ++ N K C CP + CI+ +C++ N+ SI+ T+++ ++ + C+ CP G ++ TNK C+KC+ CPK+C G I S+ + K+CT+++G L I + G +I+ LES+L I VSL+F R L +I G +E Y+L +L+N+N+Q L+++ + +N ++ G GK F H+N KLCP KI E+ +++ +D+ D+S +NGD+ C+ +++ + N + + + N++ + +N D R+LL Y ++++ EA N+T FDGRDACG D WKI D +E D +V L++ L+P+T YA Y+ T I A GAQ+ I+Y QT + P+ + S + + + W PP PNG+I +Y + RE + +R YC E I + K E+ +DP D K+ DC C I + E++E+ F D + N ++ N S + + N D Q R S + D + + + + A RE GL HF Y + ++AC E + ++ CS ++ GADDI+ I++++ + + +++ W+ P+D N LIVNY+++I S S T CIT ++ K Y ++ +PG Y + ++A S+ G G W+ + V G + +++ +VF+ + L Y Y KK D + + S NP Y+S +VY+ DEWEVPR+ + LL+ELG G FGMV+KG F D+ CAVKTV + A+ E I FL EA+VMK+
Sbjct: 62 FSKLENCSVVEGSVQILLIDNAESKDF-ENMTFPKLKEITGYLLLYRVQGLQSLSKLFPNLTVIRGDVLFHNYALVIYELRAILDVGLTSLTTILRGSVRIEKNAHLCYVDTIDWDLIAKAGRNGHFIKDNKAHEQCPNTCPEMDCHVSSSSKTHRQQKLCWNSHACQKVC-GVDCEYQNLTCSTKH-------QCCHQECLGGCNGQLADECIACRHVVY--NRK--CMKQCPPNTFKYLGRRCIEENKCKKTR---NKLSISHD--TQDIYWKPFQGQCLPQCPQGYSESKTNKH----ECKKCKGQCPKICDGAVIDSVSSAQKLKDCTYVNGSLEIQIQGGDNIIKELESSLSSIKEIRGYLKIARSYPLVSLNFLRDLAYIHGEQLDKKE--YALLVLDNQNLQELWNWESR---------------KNKLMIKG----GKVFFHFNSKLCPNKIEELKSHAEV-MPWDERDVSPSSNGDRVACNVIDMDMEVWRVGANVVGLRWTNFR--LAHKNI--DFRSLLGYVVYFK---EAPDGLGNVTIFDGRDACGADEWKIDDVDANE-----------DPTVITLLTHLKPFTRYAAYMRTYTIASAA-----VGAQTPIIYFQTKPATPTSPVNLKAHASSPNEIVVTWFPPKNPNGVIKYYIVEGIREKDSSEFVSQRNYCNEPLVISDLKKPVQEKIPVTEDPLKFDEKQKE---EETKPKDCCSCSKKNIPTQGEETESQIQFEDFLHNKVYLKNPSFNANAGINTDLNQNLPSTTRAPASKMPFFYNITPNSNVDFTMTTNTELTSEEPSTTASPDREGRFYFKVEEMYRAVTGLHHFTEYTIEVKACQEKSRELE--QPCSSQAITTVRTLPLGGADDIEESSIIINNENLTAGIYVKWDEPKDYNGLIVNYHVEIRSSDASDYKTIPICITQLDYQKKMGYIFNDLLPGNYSLRLRATSLAGNGNWTRAVYFIVPDFRSGMRPEFLALLVIGIVFVVVSTFGAILFYAYQKKKYDNMPTMLYASVNPEYMS--AVYEPDEWEVPRDKIALLQELGQGSFGMVYKGEFTTEDRGLMKCAVKTVNETASLRERIEFLQEASVMKA 1102
BLAST of EMLSAG00000002641 vs. nr
Match: gi|1009554506|ref|XP_015912632.1| (PREDICTED: insulin-like peptide receptor isoform X1 [Parasteatoda tepidariorum] >gi|1009554509|ref|XP_015912633.1| PREDICTED: insulin-like peptide receptor isoform X1 [Parasteatoda tepidariorum] >gi|1009554512|ref|XP_015912634.1| PREDICTED: insulin-like peptide receptor isoform X1 [Parasteatoda tepidariorum]) HSP 1 Score: 484.567 bits (1246), Expect = 4.713e-143 Identity = 349/1115 (31.30%), Postives = 550/1115 (49.33%), Query Frame = 0
Query: 252 FKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRD-DCPL---LKNHLTRRACWTKATVKEVTFAIPCE-EGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLG-TQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNIST-SLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESV--LVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYK--DEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETD-DFHDIVLNTIFTSN-SISTPSSSN-DSGQKKSELLRKKRSLFGGGQKLN-----DLNIDVKKRESFVQNAIVAGSARE-----------YIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIES--KSKESTGIYCITAYEFIKN-DYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTV----KGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD---SEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
F LENC+++EG + I I E ++FPKL+EIT + ++Y +SL+ LFPNLTVIRGD L NYA V+ + ++GL SLT ILRG VRIE N LCYV TI+WD+I I+ N+ C + C + DC + K H ++ CW ++V + CE + LTC + + C +ECLGGC G +EC +C+H ++ N K C CP + CI+ +C++ N+ SI+ T+++ ++ + C+ CP G ++ TNK C+KC+ CPK+C G I S+ + K+CT+++G L I + G +I+ LES+L I VSL+F R L +I G +E Y+L +L+N+N+Q L+++ + +N ++ G GK F H+N KLCP KI E+ +++ +D+ D+S +NGD+ C+ +++ + N + + + N++ + D R+LL Y ++++ EA N+T FDGRDACG D WKI D +E D +V L++ L+P+T YA Y+ T I A GAQ+ I+Y QT + P+ + S + + + W PP PNG+I +Y + RE + +R YC E I + K E+ +DP D K+ DC C I + E++E+ F D + N ++ N S + + N D Q R S + D + + + + A RE GL HF Y + ++AC E + ++ CS ++ GADDI+ I++++ + + +++ W+ P+D N LIVNY+++I S S T CIT ++ K Y ++ +PG Y + ++A S+ G G W+ + V G + +++ +VF+ + L Y Y KK D + + S NP Y+S +VY+ DEWEVPR+ + LL+ELG G FGMV+KG F D+ CAVKTV + A+ E I FL EA+VMK+
Sbjct: 62 FSKLENCSVVEGSVQILLIDNAESKDF-ENMTFPKLKEITGYLLLYRVQGLQSLSKLFPNLTVIRGDVLFHNYALVIYELRAILDVGLTSLTTILRGSVRIEKNAHLCYVDTIDWDLIAKAGRNGHFIKDNKAHEQCPNTCPEMDCHVSSSSKTHRQQKLCWNSHACQKVC-GVDCEYQNLTCSTKH-------QCCHQECLGGCNGQLADECIACRHVVY--NRK--CMKQCPPNTFKYLGRRCIEENKCKKTR---NKLSISHD--TQDIYWKPFQGQCLPQCPQGYSESKTNKH----ECKKCKGQCPKICDGAVIDSVSSAQKLKDCTYVNGSLEIQIQGGDNIIKELESSLSSIKEIRGYLKIARSYPLVSLNFLRDLAYIHGEQLDKKE--YALLVLDNQNLQELWNWESR---------------KNKLMIKG----GKVFFHFNSKLCPNKIEELKSHAEV-MPWDERDVSPSSNGDRVACNVIDMDMEVWRVGANVVGLRWTNFRL----AHKNIDFRSLLGYVVYFK---EAPDGLGNVTIFDGRDACGADEWKIDDVDANE-----------DPTVITLLTHLKPFTRYAAYMRTYTIASAA-----VGAQTPIIYFQTKPATPTSPVNLKAHASSPNEIVVTWFPPKNPNGVIKYYIVEGIREKDSSEFVSQRNYCNEPLVISDLKKPVQEKIPVTEDPLKFDEKQKE---EETKPKDCCSCSKKNIPTQGEETESQIQFEDFLHNKVYLKNPSFNANAGINTDLNQNLPSTTRAPASKMPFFYNITPNSNVDFTMTTNTELTSEEPSTTASPDREGRFYFKVEEMYRAVTGLHHFTEYTIEVKACQEKSRELE--QPCSSQAITTVRTLPLGGADDIEESSIIINNENLTAGIYVKWDEPKDYNGLIVNYHVEIRSSDASDYKTIPICITQLDYQKKMGYIFNDLLPGNYSLRLRATSLAGNGNWTRAVYFIVPDFRSGMRPEFLALLVIGIVFVVVSTFGAILFYAYQKKKYDNMPTMLYASVNPEYMS--AVYEPDEWEVPRDKIALLQELGQGSFGMVYKGEFTTEDRGLMKCAVKTVNETASLRERIEFLQEASVMKA 1102
BLAST of EMLSAG00000002641 vs. nr
Match: gi|826441979|ref|XP_012530502.1| (PREDICTED: insulin-like receptor [Monomorium pharaonis]) HSP 1 Score: 472.626 bits (1215), Expect = 2.865e-137 Identity = 357/1147 (31.12%), Postives = 553/1147 (48.21%), Query Frame = 0
Query: 222 FLLLLLMIIPIQSEICGNTKIKIMGDLQR---DFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKE-CLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRE--NSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF--CPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSL-TVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEP-----QYESGNLVFLDESV-LVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQN----EYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHE-------DKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILV---SHNSSSDIVWLSWNPPQDPNELIVNYNI---KIESKSKESTGIYCITAYEFIKNDYRYHLP--VPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDDSEINISS-------NPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMKS 1310
F L+L + + ++ G + D++ +F L+ C I+EG + I I EPS + SFP+L EITDF ++Y N ++LA LFPNL VIRG+ L+MNYA + +L EIGL SLT+ILRG V E N LC+V TI+WD+I G I+ N+ N C C CP+ + + CW +++ C+ + D S+ KC CL GC GP+ +C C+H + N K C+ CP F + CID ECR+ S N++ I + Y+ +NDSC+ CP G + + ++C+KCE C K CPG K+ S++ + + CTH+ G L I + GK+IV LE NLG I+ +SL+F ++LR I G E YS+++L+N+N+Q L+ + + P++ +L K+ K F H+NPKLC +I ++ ++L ++ +++ +NGDK C+ +L + T G + + ++ +DIR+LL Y +++ EA +N+T +DGRDACGGD W++ D Q +G L E + +++QL+PYT YA YV T I GAQS I Y T PS S + + I W PPLK NG +THY + E D N I +R YC E + E E +++ + D +K K D +C E+ + E E S + F + + N ++ + S + L + + + +ND V+ V I+ + ++ L+HF +Y + ++AC E D K I N CS + + AD+I + N+S V L W+ P PN L+V Y I +I+ ++ ++T + CIT +F+KN Y L G Y + V+A S+ G GE++E + ++ + +++ + + + LT++ KK S N+ S NP Y+S + Y DEWEVPR ++LL ELGNG FGMV++G+ + K CAVKTV + AT E I FL EA+VMK+
Sbjct: 174 FFLILAVCNHVAADNTGPNGVCQSIDIRNNVSEFSKLKGCRIVEGFVQISLIDRAEPSDYA-NFSFPELVEITDFLLLYRVNGLKTLANLFPNLAVIRGNSLIMNYALMAFEMMHLQEIGLHSLTNILRGSVHFEKNPMLCFVDTIDWDIIAKAGNGEHFIKDNKPLNGCP-LCEKKCPIRQTKPDQTLCWNLQHCQQI-----CDR-----KCEDRACDSMGKCCHPFCLSGCTGPTANDCVVCRHVVI--NGKE-CKDHCPKGKYKFMNRRCIDESECRQMPKSMYKNDEMI------KPHPYKPFNDSCVIECPAGYME-SEDYNNHVSCQKCEGRQCLKECPGAKVMSIESAQKLRGCTHLTGSLDIEIRGGKNIVKELEDNLGMIEEIDGSLKIVRSFPLISLNFLKNLRVIRG---NDSENKYSISVLDNQNLQELWDWNKHPNMTIL----------------AKEGRPKVFFHFNPKLCLHEIEKLRVNAKLE-EFSDHEVASNSNGDKIACNVTELETEVTWRTPVGAIIKWTAFKH--------HDIRSLLGYVVYFI---EAP--NQNVTMYDGRDACGGDGWRVEDVSADSTTLLANQTHNGTQTDLQEHLHILTQLKPYTQYAYYVKTYTIAT-----ERSGAQSKITYFTTKPDAPSSPRALSTWSNSSNELVISWFPPLKKNGNLTHYRIVGRWEPDDQNFIDQRNYCDEPMPLLETKSPEDVIAEQEKKHFDLEK------EFAKTDSCVCSDREVTDQSMLEKEVSSSIAFENALHNQVYVKRAQSRRRRHIGEMLNATTELPRDSTYNQNWESIND---KVENGTVLVFERIIPSTNLTFVMRNLRHFTAYNIEVQACRELDASELNDTKVIPKN--CSMKSMKTYRTLSMTNADNIPPNSFTLIKSGENNSLATVTLFWDEPVQPNGLVVTYQIEYKRIDIENIKAT-VVCITRRDFVKNGNSYTLKELSAGNYSIKVRATSLAGNGEYTEVKYFFIEEYGTLGTFWIIFCSIIGVFITSVSLLTFYIIKKR--SMRNVPSMRLIATVNPEYVS--TSYVPDEWEVPRKKIQLLRELGNGSFGMVYEGLAKDVVKGKPEVRCAVKTVNENATDRERIEFLNEASVMKA 1244
BLAST of EMLSAG00000002641 vs. nr
Match: gi|731269306|ref|XP_010603891.1| (PREDICTED: insulin receptor isoform X2 [Fukomys damarensis]) HSP 1 Score: 459.914 bits (1182), Expect = 5.562e-135 Identity = 370/1140 (32.46%), Postives = 541/1140 (47.46%), Query Frame = 0
Query: 242 IKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC----PGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVP----SEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIK--------EDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSL------------FGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHN-SSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ--SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQN-----SVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+ I +L R +LENC+IIEGHL I + + +P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL SL +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + CP +L R CWT + ++V I G T QG C ECLG C P +C +C++F C TCP P+ F DW C++ CR+ S +Y I+N CI CP G + +L C C CPKVC I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR LR I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S+ T N+ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P ++P+ +S L+ L+P+T YA++V TL+ ++ GA+SDILY+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K E Y ++ N+ + +++ + K D + K E E S F D + N +F + S DSG + RK+RSL G L+ +++ + E +V S + GL+HF YR+ L+AC++D P +RCS V + + ADDI G V+H ++ V L W P++PN LIV Y + +E + + ++ R PG Y V ++A S+ G G W+E T+ V SS++ ++ PL+F+F+ + + Y + +K + SSNP Y+S + SVY DEWEVPR + LL ELG G FGMV++G I + AVKTV + A+ E I FL EA+VMK
Sbjct: 1 MDIRNNLTR-LHSLENCSIIEGHLQILLMFKTKPEDF-RDLSFPKLVMITDYLLLFRVYGLESLRDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDICPGTAKGKTSCPATVLNGQFIER-CWTHSHCQKVCPTICKSHGCTA-QG--------LCCHSECLGNCSEPDDPTKCVACRNFYLDGR----CVPTCPPPYYRFQDWRCVNFSFCRD-----LHDSCRNSRKQGCPQYVIHNGRCIPECPSGYTM----NSSNLMCTPCLGPCPKVCNLLDSVKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIQGKDL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSSIRT---------NFDKILLKWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIEPPPRSNDPKLQS------HPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDILYVQTNATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWQRQEED-SELYELDYCLKGLKPPSRAWSPPFESYDAQKRNQS------EYEESAGECCSCPKTDSQILKELE-----ESSFRKTFEDYLHNVVFVPR-----NPSADSGAQDPRPSRKRRSLAEAANATTAVPSVPGFSNLSSVSVPTDQEEHRPFEKVV--SKESLVISGLRHFTGYRIELQACNQDA----PAERCSVAAYVSARTMPEAKADDIVGP---VTHEIFDNNAVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCVSRKHYALEKGCRLRGLQPGNYSVRIRATSLAGNGSWTEATYFYVTNYYVSSNIAKMIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIVKGEAETRVAVKTVNEAASLRERIEFLNEASVMK 1041
BLAST of EMLSAG00000002641 vs. nr
Match: gi|731269304|ref|XP_010603890.1| (PREDICTED: insulin receptor isoform X1 [Fukomys damarensis]) HSP 1 Score: 459.529 bits (1181), Expect = 6.853e-135 Identity = 370/1141 (32.43%), Postives = 541/1141 (47.41%), Query Frame = 0
Query: 242 IKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC----PGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVP----SEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIK--------EDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSL------------FGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQN-----SVYKADEWEVPRNSVELLEELGNGCFGMVHKGIF--IGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+ I +L R +LENC+IIEGHL I + + +P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL SL +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + CP +L R CWT + ++V I G T QG C ECLG C P +C +C++F C TCP P+ F DW C++ CR+ S +Y I+N CI CP G + +L C C CPKVC I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR LR I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S+ T N+ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P ++P+ +S L+ L+P+T YA++V TL+ ++ GA+SDILY+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K E Y ++ N+ + +++ + K D + K E E S F D + N +F + S DSG + RK+RSL G L+ +++ + E +V S + GL+HF YR+ L+AC++D P +RCS V + + ADDI G V+H ++ V L W P++PN LIV Y + +E + + ++ R PG Y V ++A S+ G G W+E T+ V SS++ ++ PL+F+F+ + + Y + +K + SSNP Y+S + SVY DEWEVPR + LL ELG G FGMV++G I + AVKTV + A+ E I FL EA+VMK
Sbjct: 1 MDIRNNLTR-LHSLENCSIIEGHLQILLMFKTKPEDF-RDLSFPKLVMITDYLLLFRVYGLESLRDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDICPGTAKGKTSCPATVLNGQFIER-CWTHSHCQKVCPTICKSHGCTA-QG--------LCCHSECLGNCSEPDDPTKCVACRNFYLDGR----CVPTCPPPYYRFQDWRCVNFSFCRD-----LHDSCRNSRKQGCPQYVIHNGRCIPECPSGYTM----NSSNLMCTPCLGPCPKVCNLLDSVKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIQGKDL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSSIRT---------NFDKILLKWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIEPPPRSNDPKLQS------HPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDILYVQTNATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWQRQEED-SELYELDYCLKGLKPPSRAWSPPFESYDAQKRNQS------EYEESAGECCSCPKTDSQILKELE-----ESSFRKTFEDYLHNVVFVPR-----NPSADSGAQDPRPSRKRRSLAEAANATTAVPSVPGFSNLSSVSVPTDQEEHRPFEKVV--SKESLVISGLRHFTGYRIELQACNQDA----PAERCSVAAYVSARTMPEAKADDIVGP---VTHEIFDNNAVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCVSRKHYALEKGCRLRGLQPGNYSVRIRATSLAGNGSWTEATYFYVTNYSDVSSNIAKMIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIVKGEAETRVAVKTVNEAASLRERIEFLNEASVMK 1042
BLAST of EMLSAG00000002641 vs. nr
Match: gi|1008700632|ref|XP_015841731.1| (PREDICTED: insulin receptor isoform X2 [Peromyscus maniculatus bairdii]) HSP 1 Score: 459.529 bits (1181), Expect = 1.326e-134 Identity = 369/1144 (32.26%), Postives = 551/1144 (48.16%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVCP---GGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHN-SSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERT--WVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQ-----NSVYKADEWEVPRNSVELLEELGNGCFGMVHKGI---FIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA VV +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C +ECLG C P +C +C++F C TCP P+ F DW C++ C++ Y + K + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR L I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S +K DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P + + + L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ + S K + DS C C + ++ E S F D + N +F S+ + + D+ RK+RSL +++ ++ V F + + IV S E+ + GL+HF YR+ L+AC++D P++RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T +VT S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S +SVY DEWEVPR + LL ELG G FGMV++G I + +R AVKTV + A+ E I FL EA+VMK
Sbjct: 33 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVVFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDVCPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHRECLGNCSEPDDPTKCVACRNFYLDGR----CVETCPPPYYHFQDWRCVNFSFCQDLHYKCRN---SRKPGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCQILDGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQEKNDIALKTNGDQASCENELLKFSFIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAED-SELSELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYEDSASEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAEDTRPS-----RKRRSL----EEVGNVTATVPTLPDFPNISSTIVPTSQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDA----PDERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYYVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGKAKDIIKGEAETR-VAVKTVNESASLRERIEFLNEASVMK 1080
BLAST of EMLSAG00000002641 vs. nr
Match: gi|1008700630|ref|XP_015841714.1| (PREDICTED: insulin receptor isoform X1 [Peromyscus maniculatus bairdii]) HSP 1 Score: 458.373 bits (1178), Expect = 3.494e-134 Identity = 368/1145 (32.14%), Postives = 550/1145 (48.03%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVCP---GGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHN-SSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQ---SSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQ-----NSVYKADEWEVPRNSVELLEELGNGCFGMVHKGI---FIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA VV +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C +ECLG C P +C +C++F C TCP P+ F DW C++ C++ Y + K + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR L I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S +K DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P + + + L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ + S K + DS C C + ++ E S F D + N +F S+ + + D+ RK+RSL +++ ++ V F + + IV S E+ + GL+HF YR+ L+AC++D P++RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T+ V S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S +SVY DEWEVPR + LL ELG G FGMV++G I + +R AVKTV + A+ E I FL EA+VMK
Sbjct: 33 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVVFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDVCPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHRECLGNCSEPDDPTKCVACRNFYLDGR----CVETCPPPYYHFQDWRCVNFSFCQDLHYKCRN---SRKPGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCQILDGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQEKNDIALKTNGDQASCENELLKFSFIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAED-SELSELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYEDSASEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAEDTRPS-----RKRRSL----EEVGNVTATVPTLPDFPNISSTIVPTSQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDA----PDERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGKAKDIIKGEAETR-VAVKTVNESASLRERIEFLNEASVMK 1081
BLAST of EMLSAG00000002641 vs. nr
Match: gi|568953122|ref|XP_006508763.1| (PREDICTED: insulin receptor isoform X2 [Mus musculus]) HSP 1 Score: 456.447 bits (1173), Expect = 1.556e-133 Identity = 368/1144 (32.17%), Postives = 550/1144 (48.08%), Query Frame = 0
Query: 235 EICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSE-GFIHIQRNENRNVCSDYC------RDDCP--LLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQE-ECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKC-EFCPKVC---PGGK-IRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKII--FEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKII--WEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKE-----DYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFTSNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF--VQNAIVAGSAREY------------IAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPILVSHNS-SSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEF-IKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERT--WVTVKGQSSSVVLYVMVPLVFIFILAAAVALTYFYYKKHDD----SEINISSNPRYISQ-----NSVYKADEWEVPRNSVELLEELGNGCFGMVHKG---IFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+C I+ +L R LENC++IEGHL I + + P R LSFPKL ITD+ +++ ESL LFPNLTVIRG L NYA V+ +L E+GL +L +I RG VRIE N LCY+ TI+W I+ E +I + +++N C D C + +CP ++ R CWT + ++V I G T +G C KECLG C P +C +C++F C TCP P+ F DW C++ C++ + + K + Y I+N+ CI CP G + +L C C CPKVC G K I S+ + + CT I+G L IN+ G ++ LE+NLG I+ VSL FFR L I G + YS L+N+N++ L+ + + + IT+ GK F HYNPKLC +I +M + S ++ DI+ TNGD+A C + L S T ++ KI+ +E D R LL + + Y+ EA Y +N+T+FDG+DACG + W ++D P + + + L+ L+P+T YA++V TL+ ++ GA+SDI+Y+QT + PS + +S SS +II W+PP PNG ITHY + R+ D + + E YC + K+ ++ + S K + DS C C + ++ E S F D + N +F S+ + + DS RK+RSL +++ ++ F V + IV S E+ + GL+HF YR+ L+AC++D P++RCS V + + ADDI G V+H +++V L W P++PN LIV Y + E + C++ F ++ R PG Y V V+A S+ G G W+E T +VT S++ ++ PL+F+F+ + + Y + +K + SSNP Y+S +SVY DEWEVPR + LL ELG G FGMV++G I + +R AVKTV + A+ E I FL EA+VMK
Sbjct: 33 EVCPGMDIR--NNLTR-LHELENCSVIEGHLQILLMFKTRPEDF-RDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEE-CGDVCPGTAKGKTNCPATVINGQFVER-CWTHSHCQKVCPTICKSHGCTA----EGL-----CCHKECLGNCSEPDDPTKCVACRNFYLDGQ----CVETCPPPYYHFQDWRCVNFSFCQDLHFKCRN---SRKPGCHQ--YVIHNNKCIPECPSGYTM----NSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL--EIGNYSFYALDNQNLRQLWDWSKH---NLTITQ------------------GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRT---------SFDKILLRWEPYWPPDFRDLLGFMLFYK---EAPY--QNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT--FSDERRTYGAKSDIIYVQTDATNPSV--PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAED-SELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASEC--------CSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAEDSRPS-----RKRRSL----EEVGNVTATTLTLPDFPNVSSTIVPTSQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDS----PDERCSVAAYVSARTMPEAKADDIVGP---VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL-CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYYVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETR-VAVKTVNESASLRERIEFLNEASVMK 1080
BLAST of EMLSAG00000002641 vs. nr
Match: gi|939644127|ref|XP_014295647.1| (PREDICTED: insulin-like receptor [Microplitis demolitor]) HSP 1 Score: 460.685 bits (1184), Expect = 1.991e-133 Identity = 365/1205 (30.29%), Postives = 565/1205 (46.89%), Query Frame = 0
Query: 156 SSYNDTPTLKDDGHPQRVPHLNQQEQQHTPRDYSRKRGFRKTSHFFFRFYNRRKFKFQWSLSGIANFLLLLLMII-------------PIQSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIYDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCE-FCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLI-GKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNIST-SLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSETDDFHDIVLNTIFT----SNSISTPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESFVQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPI---LVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTG--IYCITAYEFIKND---YRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMV-PLVFIFILAAAVALTYFYYKKH----DDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRP---CAVKTVKKGATHHETITFLIEATVMKS 1310
SS ND +K D +V +N+Q + G K++ R ++ F W G+ +L+L I+ P + E+C + I+ + F L+ C ++EG + I I + SA + L+FP L EIT + ++Y N S+ LFPNLTVIRG L +NYA V NL E+GL SLT ILRG VR E N LCYV T++WD+I G I N+ +N+C C CPL L CW +++ C GN S E C+ CLGGC G + +C C+ + DN C CP F + CID +CR+ K + RE Y+ +N+SC+ CP G + ++ +C+KC+ C KVC G + S+ + + CT I+G L I + GK++V LE NL I+ +SL+F ++L+ I G + + Y+L +L+N+N+Q L+ + P I + K ++G K F H+NPKLC I ++ + LS + +++ +NGDK C+ +L + T + + ++ +D R+LL Y +++ EA + +T +DGRDACGGD W+ +D V SE ES NL+ + L++QL+PYT YA +V T IA + GAQS + Y TL +PS+ + + S S + + W PPL+ NG +T+Y++ RE+ D N + +R YC + + E K + ++ + ++ C+C ++ + E E S + F D + N ++ N+ S D S+ L+K + QK L V S ++ L+HF +Y + L+AC E + D + RCS + + ADDI + + N+S IV L W P PN LIV Y ++ + + + CI+ +FI ++ LP G Y V V+A S+ G G SE +V + S+ V +++ + I IL ++ Y +K + + NP Y+S + Y DEWEVPR + L ELGNG FGMV++G+ K+ +P CAVKTV + AT E I FL EA+VMK+
Sbjct: 60 SSMNDKSRVKTDWRSDKVTLINRQCFMKP----MYRCGIVKSAASVVR-WSFEGGTFSWF--GLIWIILILCPIVTASFTERSTQTFHPTEGEVCQSIDIR---NSVTQFSRLKGCRVVEGFVQILLIDHADDSAYT-NLTFPDLVEITGYLLLYRVNGLRSVGQLFPNLTVIRGHSLFINYALVAFEMMNLQEVGLYSLTDILRGSVRFEKNPMLCYVDTVDWDIIAKAGNGEHVIADNKLKNLCP-VCEKHCPLRLTKLDDNLCWNGQNCQKI-----------CKCGNGACNPSGECCNPLCLGGCTGQTASDCKICRDVILPDNK---CAKQCPHNMYEFLNRRCIDEHKCRK-----MRKPLEAFGNVREFPYKPFNNSCVIECPAG--YMDDENNGKASCKKCDGACSKVCSGASVDSIASAQKLRGCTRIEGSLEIQIKGGKNMVKELEDNLNMIEIIDGYLKIVRSFPLISLNFLKNLKLINGSQLENDK--YTLAVLDNQNLQELWDWDTHPPITI--------KSKDG--------PAKIFFHFNPKLCIHNIEKLRDVANLS-QFTDLEVAPNSNGDKVACNVTELKVQVIKKTAEAALIEWKAFEH--------HDPRSLLGYVVYFI---EAP--NRTVTMYDGRDACGGDGWR-VDDVASESSNESSNLII---TALLTQLKPYTQYAFFVKTYT---IATERS--GAQSKVQYFTTLPGEPSQPKAFSVWSNSSSELVMSWLPPLRKNGNLTYYKITGKREVYDPNILAKRDYCDKPLQFPE--KKPITEIAEEERKRAEAEKERTKPDVATCECADRESDQSIREKEVSSSIAFEDALHNQVYVKRVGGNNRRKRDISTDFKPNDSDSLKKNETEEDSEQKFERL---------------VPSSNLSFVMRNLRHFATYNIELQACREPVPD-DVSQRCSTKIIQNCRTLPFEHADDIPTGSLKLEKIHGNTSRPIVKLQWKEPLKPNGLIVAYQVEYKRVGMPNIQPIVVCISRQKFISDNKSCITKDLPA-GNYSVIVRATSLAGSGADSEVLYVYIDEDSAKEVFWIVFWSVSSIVILITSLTTVYVCKRKLLQNVPSRRLIATVNPEYVS--TAYVPDEWEVPRKKIRLSRELGNGSFGMVYEGVAKDISKL-KPEIRCAVKTVNENATDRERIEFLNEASVMKA 1168
BLAST of EMLSAG00000002641 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold892_size84543-snap-gene-0.16 (protein:Tk08291 transcript:maker-scaffold892_size84543-snap-gene-0.16-mRNA-1 annotation:"insulin receptor-like isoform x2") HSP 1 Score: 640.573 bits (1651), Expect = 0.000e+0 Identity = 411/1208 (34.02%), Postives = 622/1208 (51.49%), Query Frame = 0
Query: 197 TSHFFFRFYNR-----------RKFKFQWSLSGIANFLLLLLMIIPIQS-EICGNTKIKIMGDLQRDFKALENCTIIEGHLAI---YDIAEVEPSALSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDY-CRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGL----TCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEFCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLIGKSIVDGLESNLGK-IDV-------------SLDFFRSLRHIAGIHYPSQ-EKYYSLTILENENIQTLFSFGEKPDIRVLITEQEQYKDENGDLVTGKQLSGKTFIHYNPKLCPQKIVEMIKESQLS-TDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNVSYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRDACGGDYWKIIDKVPSEPQYESGNLVFLDESVLVSQLQPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNL-----TKCDCDMCKAPE-------------IQNEYEKSETDDFHDIVLNTIFTS---------NSISTPSSSNDSGQKK-------SELLR--KKRSLFGGGQ----KLNDLNIDVKKRESFVQN------------AIVAGSAREYIAEGLKHFGSYRVTLRACHEDKKNIDPNDR------CSDDLTVFLKVSNKPGADDIKGRPILVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKESTGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLY-VMVPLVFIFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
+SH+ F F +R + + SL+ + +++LL +P S IC + KI Q +F LE CT+IEG+L I ++ EV+ L+FP L+EITD+ ++Y A+ + + LFPNL+VIRG+ L+ N+A VV NL IG + LT +L GGV++ N LCY+ +INW I+ S+ HI EN C C CP + RR CWT++ + V C+E + C+ NDGT + CS ECLGGC + C++C+H W N + C CP P L++ DW CI+ +C + + + ++ Y+ CI+ CP T++ K+ TC++C CP C GG I SL+DL +++CTH+ ++V LE LG+ I++ SLDFF SL+ I G+ + K+YSL ILENEN++ LF+ G+ + + +++ D + G+ FIHYNPKLC +I +M++ S + + ADIS TNGDKA+CS KL+++ L +++ NYQ++I +QN D+R LL YEIHYR + +ATY+ +N +++ GRDACG D W +ID P + ++ F +E+ ++PYTYY++++ TL++++ IQGAQS++LY+ + E P K++++S+ I W PP PNG I HYE+ + + D RI E+ YC Y+ N + +KK S ++ +CDC C P I+N EK D F D+V+N F S ++ SSN++ Q K + L++ K +F G + K N+ + + + V+N + VAGS + + LKHFG Y + +RACH K P+D CS + F +V+ KP ADDI G ++ HN SD +SW+PP DPN++IV YN++ +SK CI AY+ YRY +PV G Y VSVQAVS+ G G W+E +V Q +Y ++VP++ I + L + + SE ISSNP Y + Y ADEWEV RN + +ELG G F V+KG + P + A+KT K+ A+H+E + FL EA +MK
Sbjct: 247 SSHWNFGFRSRSSMRRNLGQSTKSYAAPGSLTCLFLSMMVLLSWVPQSSARICSSLKI------QMNFGDLEGCTVIEGNLVIMSGFETMEVKEEDYITNLTFPDLKEITDYMLVYKASRIVTFSKLFPNLSVIRGNKLLGNWALVVFQNENLVNIGFKGLTRLLHGGVKVMENPSLCYIESINWKEII-NSDYHSHIDFEENNRFCPGLKCSQLCPT-EEPTGRRLCWTESDCQRVERK--CDESVDSDNICFTNNDGT---VNTCSSECLGGCSSHDSKICWACRHVRWDSNQEIKCSNECPLPLLVYKDWRCINKSDCSH----METYNHAGAGFKEGLSFKSYDSKCIEHCPRDTKEEIGKDGVP-TCKQCIDCPNPCDGGVITSLEDLKLFEDCTHV----------PNVVQHLERTLGRVIEIQGFLKISRVFSLNSLDFFSSLKKILGVQANEENSKFYSLIILENENLRKLFTIGKNNET----VKVQRHGDPDS--------KGQAFIHYNPKLCKSEIKKMLRFSNMEDPGENSADISYATNGDKALCSPEKLDVTVQKNGLFLILTFSNYQEMILKQNPEADVRGLLGYEIHYREISKATYISRNQSKYGGRDACGSDGWTVIDHTPVGSNIDDNSIQFPNETSFFP-VKPYTYYSIFITTLLLKEYEGTKGIQGAQSEMLYVLSNEGFPEVPRDIHFIKVNHTSLNISWVPPRAPNGKIHHYELVLELKETDEVRISEQDYCHSPL-----YQGNSGNPPSGDTRVSTKKKSSSQNSGQFDPNIECDCQACLDPRRTGSISDGGTDISIENRIEK---DAFMDLVINRAFDSPRGLERRKRRALQAWLSSNETIQSKLSTDSRDNTLIQDPKIEEIFDGTRRTPVKANNRRVATRPNNTVVRNVDGTIKYYITFSSEVAGSRHQMLVTNLKHFGFYSLKIRACHAPK----PDDEGGLVKWCSGTVPKFERVAPKPKADDIHGNLQILPHN-DSDTATISWHPPTDPNDIIVKYNVRYKSKETAKYSTSCIQAYKLQAMKYRYQMPVVGNYLVSVQAVSLSGPGNWTESVFVKGPNQRGPSWVYTILVPILGIAVFVLICILLWHKWVTGKGSEPIISSNPLY--EVMQYVADEWEVNRNVIVRGDELGKGAFATVYKGTYKDPRQGFIHVAMKTPKENASHNECMLFLNEAHMMK 1398
BLAST of EMLSAG00000002641 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold383_size189472-snap-gene-0.28 (protein:Tk11344 transcript:maker-scaffold383_size189472-snap-gene-0.28-mRNA-1 annotation:"insulin receptor-2") HSP 1 Score: 478.789 bits (1231), Expect = 1.036e-146 Identity = 363/1223 (29.68%), Postives = 578/1223 (47.26%), Query Frame = 0
Query: 233 QSEICGNTKIKIMGDLQRDFKALENCTIIEGHLAIY-DIAEVEPSA---LSRKLSFPKLREITDFFIMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGS-EGFIHIQRNENRNVCSDYCRDDCPL-LKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGC---YGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLM------------------------FNDWICIDIKECRE--NSYIVNEKSITEKSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEFCPKVCPGGKIRSLDDLHQYKECTHIDGDLSINLIGKSIVDGLESNLGKID--------------VSLDFFRSLRHIAGIHYPSQEKYYSLTILENENIQTLF---SFGEKPDIRVLITEQEQYKDENGDLVTGKQLS-GKTFIHYNPKLCPQKIVEMIKESQLSTDYDKADISEFTNGDKAICSHFKLNISTSLTVNGLNV-----SYDNYQKIIFEQNSTNDIRALLRYEIHYRIVDEATYLKKNLTQFDGRD--------ACGGDYWKIIDKVPSE---------------------------PQYESGNLVFLDESVLVSQL-------------------QPYTYYALYVATLMIRDIANRHNIQGAQSDILYIQTLESKPSKLGKYEIEKLSYSSVKIIWEPPLKPNGIITHYEMNITREIMDHNRIMERPYCQENYKIKEDYKDEQSNKDKDPDNLDSKKTVSVLSNLTKCDCDMCKAPEIQNEYEKSET---------DDFHDIVLNTIF--TSNSI--------------STPSSSNDSGQKKSELLRKKRSLFGGGQKLNDLNIDVKKRESF-VQNAIVAGSAREYIAEGLKHFGSYRVTLRACHEDK--KNIDPNDRCSDDLTVFLKVSNKPGADDIKGRPI--LVSHNSSSDIVWLSWNPPQDPNELIVNYNIKIESKSKE---STGIYCITAYEFIKNDYRYHLPVPGAYYVSVQAVSVYGFGEWSERTWVTVKGQSSSVVLYVMVPLVF-IFILAAAVALTYFYYKKHDDSEINISSNPRYISQNSVYKADEWEVPRNSVELLEELGNGCFGMVHKGIFIGPDKISRPCAVKTVKKGATHHETITFLIEATVMK 1309
E+CG+ I + D+ LENCT+IEG++ + + EP + +L+FP ++EITD+ ++Y A+ SL+ LFPNLTVIRG++L+ A ++ NL +IGL+SLT ILRGGV I+ N LCYVHTINW+ IV + G + I+ +C C CP + H R CW K +++ E C+ ++G +E CS+ CLGGC G + C SC+ D CR+ CP FL+ + + CI ++C N Y+ K+ ++ Y C++ CP T++ +E +TC + CP VC G ++ ++ DL + CT I G L+I L GK++V LE L K+ +SLDFF SL I G + QE +SLT+L NEN++ LF + G+ I +K E G++++ G FIHYNP LC +I ++ + ++T + IS+ +NG+K IC +L ++ + ++ + ++ +QK I EQ+ +DIR LL Y++H++ + AT+ +NLT++DGRD AC D W I + P E + E + L S L++ L +P+TYY ++V TL++R+ I+GAQS I+YIQ P++ I ++++++ + W PPL PNG I HYE+ + E+ + C N E + P +S + CDC C +Q E ET + F+D+++N++F T N+ S P+ S E+L + ++ + D + R F V + V A + L+HFG Y+V +RACH+ K NI CS ++ +V KP A+DI + L ++ SSS I+ +W PP DPN +I Y + ++K ++ + + C+ +F + +RY LPV G+Y+VSV+A+S G G W++ W+ + SV +++VP +F I A V + Y +++ + + NP Y Y AD+WE+ RN V + +G G F MV+KG + D+ A+K + A H E + FL EA +MK
Sbjct: 31 HGEVCGS--ITLNSTNLSDYIHLENCTVIEGNVGVMIGLETFEPPEEVEVLARLTFPNIQEITDYLLIYRADKLTSLSRLFPNLTVIRGNELLGESALTILQNENLKDIGLKSLTTILRGGVTIKGNPLLCYVHTINWERIVSRAFFGNLEIEDGYESTLCPFECPGRCPQDGREHGKMRLCWNKNHCQKIQLEQCTTEDAHCHL---DSQGEVEVCSRNCLGGCSRHSGSNHTLCRSCQDVRTPDG----CRSECPQDFLLVITANLIMFPLFVIFCQCQHSVFQYKSYRCISKEDCPNIGNQYVGEVKT----------TFKDYQGKCLRQCPHNTKE---EEGTCITCS--DDCPTVCGGAEVTTIQDLEKLNGCTIIKGTLAIQLSGKNVVQKLEEALSKVRIIEGSLKISRVFSLISLDFFTSLEVIEGKDH-GQE--FSLTLLNNENLRKLFPTNASGQGIQI---------HKHE------GRRVAPGLGFIHYNPHLCRTEIERLLSSAGMNT---TSHISDLSNGNKGICDPLELEVNATAQISPFGIPEIMLQFEGFQKKIQEQDLKHDIRGLLGYQVHFKKISLATFQAENLTRYDGRDACLESCSSACPKDIWHINEFQPVESTILAPTVANVSEAQRVNESHSNVSQSSKIELSPKIILQNSSLINSLGNRTQLQLTWPDEILSIKVEPFTYYGVFVTTLLLREYEGTKTIRGAQSKIMYIQAAVYFPTEPRDVHIVGVNHTALNVTWLPPLSPNGEIDHYEVVV--ELKTKQPHVSTEDCVMNSPSYESPMTSTTTTSAPP-------LMSSPNETETCDCSGCP---VQEEQLVQETISLVGTISQNMFNDLIMNSVFRKTGNTSRNLNRRRRSVDQRESVPTKETTSHPPVPEVLVYDQLGSEPSWQVPEPEYDPETRSYFRVYSTRVHPEATHLLLNPLQHFGDYQVKVRACHKAKLVDNIL-TKWCSPTVSERPRVPPKPMANDILSSSLRHLPTNGSSSAII--TWLPPSDPNGIIERYIVSHKAKMEDDESANSVSCVFPQKFKDSKFRYQLPVEGSYFVSVRAISQSGRGNWTDYIWL----EQRSVDWFIVVPSLFAILAFAVLVCIGYLIWRQKQNKNAFSTQNPNYCPME--YIADDWEINRNLVHAGDHIGKGAFAMVYKGTYHHLDQGDIQVAIKMPHEDAGHLECMQFLQEAHLMK 1187 The following BLAST results are available for this feature:
BLAST of EMLSAG00000002641 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000002641 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
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BLAST of EMLSAG00000002641 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 3
BLAST of EMLSAG00000002641 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 25
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BLAST of EMLSAG00000002641 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 25
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BLAST of EMLSAG00000002641 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000002641 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 2
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s1534:13768..20494- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000002641-685407 ID=EMLSAG00000002641-685407|Name=EMLSAG00000002641|organism=Lepeophtheirus salmonis|type=gene|length=6727bp|location=Sequence derived from alignment at LSalAtl2s1534:13768..20494- (Lepeophtheirus salmonis)back to top Add to Basket
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