Query:   83 LCPFCKIVYYCSEEHYIIH---RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLV------DGSYY-CSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIK-------KENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA-----AKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEM 522
            LC  C+ V YCS EH   H    H + C  F +  ++  GR++ A RDI   E IL E P V+GP     P CL C R +       G+Y+ CS C  P+C KECE    H+ EC     +NF  K       +E   S+   +  LR + +K  DP+ F K+  L DH++ER+       +   N+I F+K V   K           D+ + +I R+  IL TN   FE   P       ALYP   +I+H C  N  +    D ++   ++  I KGE +   Y       ++RR  ++Q   FDC C RC D  ELG++     C  CK G ++ +N L   + W C  C+   + K +      ++ ++ S++  T   LEE +Y ++  LH  +  ++   + L  +Y      A E L+     RK+QLC  +L+     D G++ +RG +L +M
Sbjct:   19 LCAACRNVVYCSREHQKEHWKKGHRSECQCFEIATNEVLGRHLRATRDIKIGEQILKEAPLVLGPKVASAPLCLGCHRNLLAPGKPRGNYHKCSSCSWPLCGKECEDSVHHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDPDAFLKLYNLEDHLKERLE-TPLYQVLRANLITFIKTVLGMK-----------DWPEMDILRIAAILDTN--TFEVRQPRERRKIRALYPGAAMISHDCVPNMRHRFDDDMNIVFLAKRKIAKGEILSISYTQPLRSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLKCKAGKIISLNPLLNSAPWKCQLCNFKRSAKDVVTSDAELQQELESLDKTTPVALEEFIYRHRADLHETNTHILQAKYALTQLYGSAPGFAMEELSGESLNRKLQLCEELLKLADIFDGGWSIFRGNLLIDM 466          

Query:  108 FPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVD---GSYYCSKCGVPVCDKECEIGDLHR-----PECGYFQKNNFVIKK---ENHYSSQA-----CVTPLRMLLMKKSDPNTFRKIDMLMDHIEER---VVINKQVN---IQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPD-FHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKE-----RKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVS 575
             P+ V+ S  +GRY+VA R +   E ++ E+P  +GP     P CL C+  V      Y C  C  P+C   C  G  HR      EC  + +   V  +   E    ++       V  +R+LL+++ DP  F  I  +  H EER    V+ +      +Q L +   L+                 D + +++  + GIL  N  +      + G     LYP   L+ H C  NT +   P  F + LR+   +++ E +   Y  +  G L+RR  + +   F C C+RC D  ELGT  S + C  C+ G +  ++ L    DW+C+ C   +    +   +D I + +  I+   I  LE  L  Y+ +L PNHY+++   ++L  +Y   E    P+       RK   C   LE +  +DPG T+ RG I+ E+  P+M++++   +  +I+ +EF +RL    + L  ++  L       TEN++ 
Sbjct:   47 LPYRVEHSDIYGRYLVANRQLEAGETLIREEPLAIGPCVSGDPVCLGCYHPVSLKADQYRCPGCAWPLCGSTC-AGLKHRHGHTETECQLYAERRAVAGELLTERAGPAEVRDLYELVMIVRILLLRQHDPEQFALIARMESHTEERRQNAVLWRHYEEKVVQRLRVTWQLE-----------------DLEAEQVHEVCGILDVNCFEI----GQNGAKARTLYPSAFLLAHDCTPNTAHTDDPSSFEILLRTSRRVREREALTLSYAYTLQGTLKRRAFMHEGKLFWCCCRRCSDPRELGTDCSALVCATCRTGSVRAVDPLQQTGDWACDRCAHKMGATEVERQLDRINNDLEDIDVHDIPGLENFLLRYRDVLRPNHYLLLSAKYSLCQIYGRTEGYLLPQMSPEDIARKESYCREFLEIVDVLDPGLTRLRGLIMYELHAPVMVLAQSAFQSGQISRQEFQRRLKEVVKLLQVSRDILLMEPEGSTENAMG 520          

Query:   84 CPFCKIVYYCSEEH----YIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYY--CSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQ---ACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINC--KHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA--AKETLTRPEKE--RKIQLCMSVLETLGRVDPGYTKWRGTILQEM 522
            C  C  V YCS +H    + +H+ S  C PF +  +++ GR++VA R I P E++L E P V GP     P CL C   ++   +  C +CG P+C  EC+  D H+ ECG  +     +  +          C++ +R LL+ ++      K   L + +E     + Q    L++I  F+ +   +++F            ++EI + +G L+ NG +     P      VA++       ++C  N       + H  L +   IKK   +   Y  +  G   R++ + Q   F C C+RC+D TEL T  S I C  + C  G +LP  +  +   W C  C   V    +  I++     ++S+E    + L + L HY+K L P H+ + +I   L+ + A   KE +  P+     K+     ++E   ++ P   +  GT+  E+
Sbjct:   15 CSNCNQVSYCSVQHQKQDWKVHKPS--CHPFKIAHNEQLGRHLVATRTIKPYEIVLKEAPLVRGPAQISAPVCLGCLNGIEAEDHIECEQCGWPLCGPECKSLDEHKAECGLTKDRGQKVNVQEFGGPHPLYTCLSTVRCLLIGETSTEKASKFQDL-ESLESTRRGSNQWKADLVSIGQFIPKFFKTQKFT-----------EEEIMKAVGALQINGHEVPTTDPSH----VAVFYTASFTENSCLPNLAKSFNKNGHCILWAPREIKKNAHLSICYSDAMWGTADRQRHLMQTKLFKCACERCVDVTELDTNYSAIKCEDRQC-GGLMLPTKADEWNGSWRCRECHKQVQKHYVERILERAGKDIQSMEKIAENGL-KYLKHYEKWLPPQHFHMSEIKILLVQLLAKDQKELMVIPDDRLLLKLNFARELVELYEKLTPCEVRTLGTLCFEL 448          

Query:   84 CPFCKIVYYCSEEHYIIH--RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPY---------SKKLPGCLNCF---RLVDGSYYCSKCGVPVCDKECEIGDLHRPEC-----GYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKE--VSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFE-PLGPERGCPGVALYPVYCLINHACFNNTNYVKFPD--FHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINC----KHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEH--ETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKE-----TLTRPEKERKIQLCMSVLETLGRVDP 509
            C  CK+V YC  EH   H  +H  RC PF  ++    GRY+   ++I   +++  E+P VVGP          +  +P C+ C+   RL  G + C +C  PVC   C+   +   EC     G         +  N Y     +  L+ LL+++  P  +  +  +  H EER   +     +   ++ +L++  +   K+ N N ++   D   + + R+ GI++TN M  E P G E       L+   C++ HAC  N ++ +F +    + +R+   ++KG+ +   Y +   G   R+  ++    F C C RC+D TE GTY+S + C         G  LP++ L+  + W C+ C +IV+   ++++   +  QV  +     + +++E +L     +LHPNH+   ++ H LI +Y  +       L+  + ERK++LC  +     R+DP
Sbjct:   18 CTRCKMVRYCDREHQKQHWPQHKRRCRPFSEEQDAELGRYLKVTQNIAAGQIVFIEEPLVVGPKWYLSDADKEASNVP-CVGCYTPCRL--GKHQCRRCRWPVCSAGCKHESM---ECSVLSLGSGSPTRADARSLNDYFRGDALLVLKCLLLQRQSPTKWSALLEMQSHEEERKGTDLYEEAEK-RVVTYLQKRFLCRLKQTNPNLLT---DCGPEMLHRLCGIIETNFMVIELPSGVELS----GLFRQACMMEHACQPNCDF-QFDNKTQQVAVRAGCDLRKGDHLRITYTNILWGTQLRQHHLRLTKHFSCRCSRCLDPTEYGTYISALTCLGDVNQTCGGTHLPVDPLDENTQWKCDTCPMIVDGAYVAELQSHMTEQVEGLLAGCPSANQVELLLARLTHMLHPNHFHTFNLKHTLIQLYGNEAGLELGVLSNTQLERKLRLCGELYNVCRRLDP 463          

Query:  116 KRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGC--LNCFRLVDGSYY-CSKCGV-PVC-------DKECEI--GDLHRPECGYFQKNNFVI--------KKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKE---TLTRPEKE---RKIQLCMSVLETLGRVDPGYTK 513
            ++ GR++VA+  I P + IL E+P +V P+ +    C  L C + +  SY  C +C V P+C       + ECE       +  C      NF I          EN  +   C    +ML+    + + +R  + +    EE VV  + +    L  +L  +E++S           SN F+         +   +G   +         G+ ++     + H C  NT       F+++L + +P++ G+ I+  Y +  +G  +R+  ++     +C C RC+D TE+GT+MS + CK C    +  I+S     DW C +C  ++    + ++   + S +     + +   E +L  Y  LLHPNH++++DI  N+  +  A     ++ +P K+   R+++LC  +L     V PG +K
Sbjct:   14 EKLGRHLVASIAIEPGDTILEERPLLVAPHWE----CHQLKCAQCLQESYVICRRCQVFPLCMDCNQHDEFECEFFTSGAGKALCKDILVKNFGICGLLKLLLLLENPRTKGDC----QMLIDVPINLSDYRDGEGMWQEHEELVV--RPLMESGLADVLPTQELTSDALHAHCIRIDSNSFE---------VTAKDGDTLK---------GIFVWGAT--LPHHCVPNTVVALDEQFNMKLYAAVPLQPGDIIYNSYTNPLMGTSQRQHQLRLSRRLECICSRCLDPTEMGTHMSSLKCKECPGFSVCEIDSNGKLGDWRCPDCRALLTAAEVHELQAAVGSALVDAMGD-LQVYEALLTQYGPLLHPNHFMLLDIKQNIASILRAAALMNSMDQPCKKLLARRVELCSDLLPVCRAVVPGISK 407          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKK--LPGCLNCFR-LVDGSYYCS-KCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINK-QVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLEL-RSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKH--CKNGYLLPINSLNYESDWSCNNCDVIVNYKTISD----IIDTIESQVRSIEHETIDELEEMLYHYQKLLHP-----NHYIVIDIMHNLI 476
            + +  S   GR + A RDI   ELI  E+  V GP ++K  L  C+ C   L    + C  +C +PVC+  C   + H+ EC +F++     + ++  + Q  V P+ + ++          + +     E+R +++  Q N +      + +E+  + +  +N  +T   F   ++ R++G+L TN  +              L+P+  ++NH C  N ++  F +  L + R+   I KG +I T Y     GNL R   +K    F C+C RC D TE GTY+S + C+   C+ G ++P+ +   + DW C  C+ +  +  ++      ++TI +++ S        +++M+ H+   L P     ++Y++I+   N+I
Sbjct:   57 WTISSSTVAGRGVFATRDIAAGELIFQERALVTGPTARKGQLSSCICCHETLPQTGFLCRHRCTLPVCET-CSDSEEHQAECEHFRR----WQPKDVDAEQEQVNPMSLRILTA--------VRVFHLGKEQRHLVDAMQANAERA----YRREIIQAAQCFRNFPTTDRVF-MDQLFRIVGVLNTNAFEAPCRSGGHETLLRGLFPLTAIMNHECTPNASHY-FENGRLAVVRAARDIPKGGEITTTYTKILWGNLTRNIFLKMTKHFACDCVRCHDNTENGTYLSALFCREQGCR-GLVIPVQTRTLQPDWRCITCENVFPHAKMAKYQDFALNTINNRINSC------SVQDMI-HFINELCPRFCPSSNYVLIEAKLNVI 413          

Query:  112 VKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNF------VIKKENHYSSQACVTPLRMLLMKKSDPNT--FRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCK--NGYLL--PINSLNYESDWSC-NNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAA--KETLTRPEK---ERKIQLCMSVLETLGRVDPGYTKWRGTILQEM 522
            +K++   GR+ VA  ++   E +L E P VV P   +   C  CF L +   +C KC +    ++C   D    +C    + NF      +++K+ H   Q     L+ LL+++ +     + ++  +   +  R       N Q        +   +  ++           D+  +Q +LGIL  N   +E   PE G     LY    L  H+C  N       +  +++ +   I  GE ++  Y +  +G   RR+ +K    FDC C RC D TELGT+MS   C  C   +GY++  P   +     W C  N +  +  + +S++++  + ++     + I   E +L    +LLH NH++++D+  N+  +     +   TRP K   ERKI+LC  +L  L  V PG ++ +   L E+
Sbjct:   14 IKQNDTLGRFAVALCNVRAGETLLLENPIVVLPLMGE-RRCSKCFNLTES--FCRKCRLLALCEDC--SDHDERDCKRLAEMNFSDDQVELLQKKEHTEIQPV---LKCLLLREHEETLPLYEEMSQMDSQLMTRRGTEVWKNYQ--------EHAFTPLDYGGVLAQLRGAADEDLVQGLLGILDINA--YEIRAPEVGGAMRGLYRRAGLFAHSCTPNLVISIDDEQRIKVYANRFIAAGEILYNCYTNVLLGTEERRKILKVGKCFDCSCPRCQDPTELGTHMSSFICSQCSCVDGYIVRQPDTGI-----WQCLLNPEHTLKQEFVSNMLERAKEEIFHA-RDDIYRQELLLAKLSRLLHRNHFLMLDLKQNIASILRQILQNMGTRPNKKVYERKIRLCQEILLVLKVVTPGISRLKAIALYEL 418          

Query:  119 GRYMVAARDINPLELILSEQP-AVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVP-VCDKECEIG--DLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSS-KEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCP--GVALYPVYCLINHACFNN-TNYVKFPD-------FH----LELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTE 384
            GR +   RD++  E++ +E   A V   S  L  C +CFR     + C++C     CD+ C+    D HR EC    +N      EN       +  ++      SD +    +DML DH+      +             LKE+ +  K F       S    +  +  + G++  NG     L  +RG    G+ L+P  CL+NH C+ N T  +   D       FH    +ELR+  PI  G+++   YV     +  R++ ++Q ++FDC+C+ C++ T+
Sbjct:   18 GRGLRGTRDLSAGEVVFAEASFAAVVLDSLSLQVCHSCFRRQVNPHRCAQCKFAHYCDRTCQRAAWDEHRKECSAI-RNIGKAPNENVRLVARILWRIQKHTGLVSD-SQLTTLDMLEDHLSRMTPED-------------LKELKADVKTFYTYWPKKSKAVGEDYVSHLFGVISCNGF---TLSDQRGLQSVGIGLFPNLCLVNHDCWPNCTVILNHGDQSALDASFHSSRRIELRALEPISAGQELTVSYVDFLSVSTDRQRLLQQQYYFDCKCEHCVNGTK 284          

Query:  115 SKRFGRYMVAARDINPLELILSEQPAVVGPYSKK---LPGCLNCFRLV-DGSYYCSK-CGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQ---RMLGILKTNGM--KFEPLGPERGCPGVALYPVYCLINHACFNNTNYV-KFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCK-NGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRS-IEHETIDELEEMLYHYQKLLHP-NHYIVIDIMHNLIH 477
            SK  GR +VA R +   E+I  + P ++G  + +   L  C  C +++ D  + C + CG+PVC   C     H+ +C  F+                            ++P+    + + +  +   + ++K+    +  +   L     ++  N  +   +   D+K I+   R + +L+TNG     +     +     ALYP++ ++NH C  N  Y  +    ++ +R+ + I +G ++ T Y     GN+ R   +K    F C+C RC D TE G ++SG+ C+     G ++P  +     +W+C  C     +  +    D     + + +   ++  L + L        P ++Y+VID   +++ 
Sbjct:   30 SKIAGRGVVATRSLKRGEIIFRDSPLLIGLAAHEEDSLNACSVCLKMLPDTRFMCRQGCGLPVCSL-CAKKKQHKSDCDLFKS------------------------WGPNEPDVANSVVIRLLCVARAINLSKEQRDLIYCLQANLDNNHRTEVRNAAKCFKNFPTDKKLIEIMNRTVAVLRTNGFDKTTDRTNDNQEFNYRALYPLFGVVNHDCIPNAYYTFEEKTNNMIVRAAVDIPEGFEVTTTYTKLFTGNIARHLFLKMKKSFTCKCSRCSDPTEKGAFISGLYCRDTNCAGLVVPEITGLPHPNWNCLVCKQKSTHAQMMKSQDFASGAINAKVNSNSLRTLVQYLNEKSDSFIPSSNYVVIDAKMSVLQ 381          

Query:  119 GRYMVAARDINPLELILSEQPAVVGPYSKKLPG-CLNCFRLVDGSYYCSKCGVP-VCDKECEIGD--LHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPN----------TFRKIDMLMDH---IEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKF--EPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCID-----RTELGTYMSGINCKHCK-NGYLLPINSLNYESDWSCNNC----------DVIVNYKTISDIIDT---IESQVRSIE-HETIDELEEMLYH 456
            GR +  ARD  P E+ILS++P +  P +      C  CF+  +    CS C V   C   C+  +  LHR EC    +    ++KE        +  +  L +K++  N           +  ++ L+ H   I+E+ ++       L+N+IL    V                 D +EI         N        L P+    G+ L+P+  +INH+C  N   V F +    +R+   I K  +I   Y+ +    L R++ +K+ + F C+C RC +       E    + G  C + K  G+LL       E  + C  C           +  + KT+S+   T    E +  +IE ++TI++L+  LYH
Sbjct:   22 GRSLFTARDFRPGEVILSQKPYICVPNNTSSESRCDGCFK-TNNLKKCSACQVVWYCGSSCQKSEWKLHRDECKALTR----LEKEKRKFVTPTIRLMVRLYIKRNLQNEKVLPITTTDNYSLVEALVSHMSEIDEKQMLLYAQMANLVNLILQFPSV-----------------DLREIAENFSKFSCNAHSICDSELRPQ----GIGLFPLVSIINHSCSPNAVLV-FEEQMAVVRAMDNISKDSEITISYIETAGSTLTRQKSLKEQYLFHCQCARCSNFGKPHDIEESAILEGYRCANEKCTGFLLRDPE---EKGFVCQKCLLLRSKEEVKKLASDLKTVSEKAPTSPSAEDKQAAIELYKTIEKLQVKLYH 368          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNN--FVIKKENHYSSQAC-VTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINK-QVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHY--QKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKC 561
            CFFCG +         C FC  +++CS++H  IHR +N C PFIVKR    GRY VA+RDI P ELIL E+PA  GPY+K +P CL C++ VDGSY C  C  P+C  EC  G +H+ EC +    N  F IK  +  +S  C +T LRMLL K SDP T+ +I  LMDH +ER       +    +N++ FL     +K F + +      F   EI+R +GIL+TNGMK E  G     PGV LYPVYCLINHAC+NNTNYVK  D HL+LR+Q+ I+ GE+I TRYVSST+GN RRR+D+ +YW+FDC C RC D TELGT+MS + C  C  G  +   +L+++SDW C  C   V  + I   +D IE ++  ++    ++LEE++  Y    LLHP HY+VI++MH+L   Y+++ +LTRP++ERK+QLC  VL+ LG VDPG+T WRG +L EM   L+++S+ DH    I E  F +RL  C R LA AKKC
Sbjct:  338 CFFCGEQT-----CNSCQFCDNIFFCSQDHLAIHRPANYCHPFIVKRDPDVGRYTVASRDIQPCELILRERPAASGPYTKTVPVCLQCYKQVDGSYLCPVCNCPMCSWECAQGSVHQLECQFAASKNAKFTIKSFDIPNSFYCNITVLRMLLTKTSDPATYTRIINLMDHDQERQSEGTYSMTAMKMNVMAFL-----TKHFGEQQ------FPDYEIERNIGILRTNGMKLEQ-GDLVSAPGVVLYPVYCLINHACYNNTNYVKCEDLHLQLRAQVAIQAGEEITTRYVSSTLGNCRRRRDLSRYWYFDCRCVRCRDSTELGTHMSSVRCS-CGEGLCVKREALDWDSDWVCQVCQRSVPGEDIVREVDQIEEELAEVDTTDTEKLEELIAGYCSHSLLHPQHYLVIELMHSLAIAYSSRHSLTRPQQERKVQLCSQVLQALGTVDPGFTTWRGKLLHEMSTTLLIMSRADHAVGIIGETLFKRRLYFCMRALATAKKC 1783          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNF------VIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINC--KHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSI--EHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA-----AKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRL 548
            CF CG +E        CPFC +V +C ++H  +HR    CFPF V   +  GR++VA RDI P ELIL++ P V  PY+K    CL C++ V G Y C  CG P+C  +C  G+LH+ EC  F+K +F      + ++++HY   A + P+R L +K +DP  + +    + H +E+               LF      S EF ++    S+++ + EI +++ I+  N +  E + P  G  G A YP +  +NH+C  NT  VK P+  LE+R+   IK+GE+I T+YV++      RR  + + WFF CEC RC DR+E G+Y+ G+ C  K C  G +LP N L  ESD+SC +C+  + +K    I+   E  +R+   ++  I+ +E  LY   KLLHP +YI++ +   L  +Y      + ETL RP  ERK+Q+C+ V++ L  +DPGY+KWRG +  E+    ++++K  H   R     + K L
Sbjct:   86 CFLCGRQES-----ITCPFCGLVAFCGDKHLNVHRPGGYCFPFTVSSEEGRGRFLVATRDIKPDELILADNPIVQTPYTKSKAQCLQCYKKVTGKYKCRICGFPMCGAQCANGELHKIECRVFEKADFEAEIDDLEEEDDHY---AAIMPIRCLYLKHNDPEMWERFTGFLGHCQEQKSFYPD---------LFDYHQEHSVEFLRDTCELSDEYTEDEIHQVISIMYINSVNME-MAPGYGL-GTAFYPTFANLNHSCICNTKSVKLPNNQLEVRALAHIKQGEEISTQYVTADKPTRIRRPMLYKKWFFWCECIRCGDRSECGSYLGGLMCPMKRC-GGTVLPDNPLARESDYSCLSCNHRLEFKQAEMILSKAEKDIRTPNNKYNLIEHMENFLYMQSKLLHPFNYIMVTVKLKLGCMYGNCPPYSAETLPRPLMERKLQVCLDVMDALDHIDPGYSKWRGKMETELSMARLIITK--HTMARPPASYYEKAL 1507          

Query:   37 PAASSKDSNG-ASPINGLTDTQDDVEVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYF----QKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCK--HCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK-ETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL 562
            P   + D NG  S I    +   +    N   CF C     E     +C  C +V +CSE+H  +HR  N CFPF+V++ +  GRY+VA RDI PLEL++ +  A +GP     P CL C +  DGS+ C  C  PVC+++C  G+ H+ EC       +K  F   KE H  +  C+ PLR+L +++  P  + ++  LMDH E+R+   +  N    ++  FLK             S+      ++I R +G+  TN       G      G A++P +  ++H+C  N  +  FP+  L L+++  IK GE+    Y+S+T G+L+RR  +   W+FDC+C RC+D TELG++ S   C+  +C  GY++   + N  + W CN C ++   + ++     I   ++ +++ ++   E+       LLHPNHY+ I +  +L+ +Y++    L   + ER  + C  V      +DPGY K RGTIL+ +     +++K+    K  TE +F +R+  C     E +KC+
Sbjct:  214 PKKEAADQNGNTSKIEKSNEEVKENTYTNLKVCFICAKPATE-----ICDICNLVGFCSEDHKKLHRPENFCFPFMVEQKEGVGRYVVATRDIEPLELVMWDNAAALGPRMGCSPACLQCLKPADGSFRCGNCNWPVCNQKCADGNAHKIECDTLKNAKEKVEFTDFKEPH-DTYRCIAPLRLLKVQEKIPEVWERLSYLMDHNEDRIKDEELWNTYQTSVNKFLK-------------SSDPSLKDEDINRAVGLYWTNAFACANGG------GQAIFPTFSFMSHSCAPNCAHSVFPNKTLALQAKTAIKAGEEFTISYISTTQGSLKRRMKLHDKWYFDCKCARCMDPTELGSFTSAHLCQVCNCPEGYVIATEAENDSAPWKCNKCGLLTPAEELNKKETEIAIDMQKVDNTSLVGFEKFHEATLTLLHPNHYLNILLKRHLVGLYSSVLSQLEAEDLERVKRYCEEVDAVYKIIDPGYQKERGTILRALCEVSKLLAKKYLNDKTETEEQFSERVKKCIELFQEGQKCM 1740          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGS-YYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQ---ACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCP-GVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDE-LEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKE-----TLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKC 561
            CF+C     + +   LC  C +V  C E H  IHR +  C PF V+  K  G  +VA RDI P E I+ ++PA++GP+    P CL C+  V  S Y C+KC +P+C  +CE G  H PEC         I  E+  S+    A V P+RML + +++P+ + ++D LMDH+E+R   +K   I+   + L  +   S  E +              ++R++GI +TN +K+E        P G AL P++ ++ H+C NNT Y +     + +R+   IKKGE+I T+Y     GN+ RR D    W F C+C RC D TELGT  S + C  C+   LLP  S + +S W C +C      +++   +  +E ++ +  +    E  E+++  +Q+ LH +H++ +     L+ +Y A+E      ++R   +RKI LC + ++   R++PGY  W+G +L+E++ PL +   +D E ++I + ++  R     + + EA +C
Sbjct:   56 CFYC-----QASPALLCEGCGLVAVCGERHARIHRPAGSCLPFTVEDRKGKGNVIVAVRDIKPFETIILDRPAIIGPFDDTNPECLECYSKVSVSGYKCTKCNLPLCGPQCEGGPTHAPECEVLAAAAPPISVEDQDSAHPVYAAVAPIRMLHVMRTNPDIWEQVDRLMDHLEDRRKEDKWDFIRDDVLPLITQRCDSLCEADI-------------VERIIGIFRTNSVKWEDKSKGICKPIGHALCPLFSMMCHSCVNNTRYTQTMAGEMIVRAVKHIKKGEEITTQYRGPNTGNILRRPDFPTNWLFSCDCPRCNDPTELGTMASTMRCPGCQEPSLLPATS-DMDSVWRCTSCQKEETLQSVITPVQLLEMELDAFPYSASPEAWEDLIRKFQQHLHDDHFLCMKAKRMLLQIYGAREGYKLDQMSRELLDRKISLCRNYIDIFSRLEPGYRVWKGRLLEELVGPLTITVNKDLEDQKIDKIQYILRYKEIVKMIKEAAQC 1513          

Query:  105 NRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHY---SSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQV-NIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGI-----NCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSI--EHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA-----AKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKED 533
             +C PF V   +  G YMVA RDI P+E++L E P VVGPY++  P CL C   VDGS+ C  C  P+CD+ C  G  H  ECG F K  +  +  +     S  A +T +R+L +K++ P  F ++  L DH E+R    + + +    +++ FLK+V               D  + EI  +LG + TN    E   P     G   YP Y  +NH+C  NT   K+ D  LE+R+Q+ I KG +I T+YV S      RR  ++  W+FDC C RC+D TE G+Y+S +     +     +G +L  N L+  SDWSC +C  + + + + +++    + +     E + I   E  ++HY   +H +HY++I I   L  +Y          L RP KERKIQ+C  +L+T+  VDPGYTK RG +L EM    +M++KED
Sbjct:  184 GQCAPFKVCYGEGVGHYMVAVRDIKPMEVVLREMPVVVGPYTQTAPQCLQCCAKVDGSFLCPHCNYPMCDQACSEGAHHAVECGLFVKCGWRAEVSDMTVTDSQYAAITVIRLLDLKRTQPEVFARLMRLEDHNEKREEEEEDLWSYHQQHVVTFLKKVCQV------------DNPESEILSVLGKMFTNCGDLE--LPATHGRGNGFYPTYANMNHSCRANTKTFKYSDQRLEVRAQVRIPKGSEISTQYVQSMKATYARRPVLRAKWYFDCACDRCVDPTECGSYLSALLCPSPSPSKPCSGLVLSCNPLSGPSDWSCQSCSTLYSAEYVINLVTEAAAMIEKPREEDDIIQHYERTIHHYSTTIHSSHYLIIGIKEKLAQIYGNFIPYKLPDLPRPLKERKIQVCQDMLDTISIVDPGYTKSRGQMLAEMNKTKLMIAKED 1476          

Query:   59 DVEVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFR-LVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVV--INKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRS-IEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKET-----LTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKKPIDEDNV 587
            D+++D    CF+CG E  E      C  C +V  C E H  IHR S  C PF V+ S   GR ++A RDI P +++L+++PA VGP+      CL C   L + SY CS C +P+C + CE G+ H+ EC   QK      KE      A V  +R+L   +++P+    +  LMDH+EER    I   V   L+  +  L     + E                +++++GI++TN +K+     +    G A+ PVY ++NH+C NNT   +  +  + +R+ + IK+GE+IFT+Y   T GN+ RRQ    YW F C C RC D +ELGT  S   C  C  G +LP++S     DW+C  C  +   + +   +  ++  + S +  ++ +  E +L  +Q  +H +H++ + I   L+ +Y  +E      L R   +RKI+LC + +    R++PG+ +WRG +L+E++ PL +   +D E   +T+ E+  ++      + EA KC     + + E  +   L +  +  N+
Sbjct:   99 DMKMDFTRTCFWCGVETMET-----CEDCGLVGVCGENHRHIHRPSGTCLPFSVQHSDEKGRLLIAVRDIKPYQIVLTDRPAAVGPFPST---CLECAAGLPEPSYLCSGCHLPLCGEGCEEGERHKIECKLLQKTGGG-GKEVEGDMSAAVGVIRILDNIRNNPDVMEMVLRLMDHLEERRKEDIWSDVTEHLIPFVTSLGYEDVAPEL---------------LEKIVGIIRTNSVKWSAGSGK--IQGYAVCPVYAVLNHSCVNNTVDTQTQEGEIMVRATMVIKQGEEIFTQYRGPTQGNILRRQQFLDYWKFCCNCARCSDPSELGTMASAGRCDEC-GGTVLPVSS-AMSCDWACGGCGRLETEEKMVATVTRLQMCLDSFLPSQSPEAWETLLTEFQAEVHEDHFLCMSIKRVLLAMYGGREGYRLEQLPRHLIDRKIELCRNYISIFSRLEPGFRQWRGEVLEELVGPLTVSMNQDMENNNLTKMEYMMKIKEIVGLVKEAAKCRQFEESNIAEKGLYKALAQSFNT*NI 1628          

Query:  107 CFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIK-KENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL 562
            C PF V   +  GR +VAARDI+ LE IL + PA+VGPY  + P CL CF   DGS  C  C +P+C ++C+ G  H+ EC +F +    +K  +N  ++   +T LR+L ++ S+P  + ++ MLMDH EE+ +  +  +    NI+ +L+          ++   ++ F  +EI R +G+++TNG+  E     +     ALYP + L++H+C  N      PD  + +R+Q+ IKKGE+I  +Y+S   GN+ RR+DI   W F+C C RC+D TELG+++S + C  C    L   NSL+ +  W C +C+  ++   +       E ++  I    +D+ E++L  Y K+ H NH+ ++ I   L    A K  +T+ + +RKI L    L     VDPGYTKWRG +L E+    M ++  D     I++  F   +      L  A  CL
Sbjct:  338 CLPFSVTHKEGVGRCVVAARDISALEEILHDYPAMVGPYYDEHPLCLECFLKTDGSTSCPLCDLPLCGEQCQGGPNHKYECSFFTELQKTVKMPKNAPNTPYLITILRLLNVRDSNPAMWDRLGMLMDHKEEQEMEKESWDNVQTNIVGWLR----------SKGGLADQFSAEEITRAIGLIRTNGINIEKPYAGQMVACKALYPTFSLLSHSCICNARIFIMPDNEIIIRAQVDIKKGEEITIQYISYLFGNILRRKDIVDNWMFECTCPRCVDPTELGSHLSSLICPACPGIVLPATNSLHCQL-WKCQSCEQTIDRAQVEKYSKECEEKMMEIYETEVDKYEDLLNEYSKIFHQNHFQILLIKKYLAR--AMKGKMTKDQIKRKITLMKEFLNGFQLVDPGYTKWRGMMLLEVSKISMFLADMDLGQGNISQDVFTSVIEQAVMDLGTALNCL 1669          

Query:   97 HYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQ-----ACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFE-PLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQ-VRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL 562
            H   H     C PF V   +  GRY+VA+RDI   E+IL + PAV+GP  +    CL C    DGS  C  C +P+C  +C  G  HR EC  F K    +               C+T LR+L ++  DP T+ ++  LMDH EER    +   +   N++ +L+           +V  ++ + ++EI R +GIL+TN  + E P    +G  G A+YP +  ++H+C  N  Y   PD  L LR+Q+ IK+GE+I  +Y+S   GN RRR +I   W F+C C RC+D TELG++MS + C  C    L   NS   E  W C  C   +    + DI+  +E + + ++EHE  D+ + +   +  LLHPNHY +  +  +L   +    TL   E E +  L    ++    VDPG TKWRG +L ++    M ++   H  +   +  F   +      L +  +CL
Sbjct:  168 HLPDHLMDKTCLPFTVMYKEGVGRYVVASRDIKASEIILCDTPAVLGPNYETEAVCLECLSRADGSVLCHHCNLPLCSDKCREGPKHRAECEVFSKMEKKVSVARFGQGTIAYEYGCITVLRLLALRDGDPETWARVQFLMDHDEERRKEKEYWKMFQKNVVDYLR----------IKVGLADTYSEEEIHRAIGILRTNAFQIEHPYLHAQGTSGKAIYPTFSFLSHSCIANARYSVMPDDKLTLRAQVDIKEGEEITIQYISFLFGNSRRRGEISSCWMFECRCPRCLDTTELGSFMSAVLCSSCPGSVLPADNSFECEV-WKCKECGQKMEQDKVLDIVKELEDEMLNTMEHEC-DKYKALEEKFSNLLHPNHYQLQILKRHLAGAFRGNMTLA--EVELRKNLLEEFIKVFEMVDPGLTKWRGKMLYQVCKTKMFLADIKHSKEETLKEVFLAEMAESIAGLEDVVQCL 1544          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYF----QKNNFVIKKENH--YSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK-----ETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLN 549
            CF+C  E ++             + C  EH +IHR    C PF V  S   GRY+VA+RDI PLEL+L ++ A VGP +  LP CL CF  VDGS+ C KC  P+C  +C   +LH+ EC  F    +K NF    E H  YS+   + PLR++L+KK +   +  +  LMDH +ER   + ++      I+ F  +     E   + VS+      +E+  ++G+L TNG + +      G  G A+YP   L +HAC  N  +   P + + L++Q+PI+KG ++  RY     G+L+RR+ I + WFFDC C RC D TE G+  S + C  CK G +LPI+SL+  S W C+ C    + K I D+ + +++++  +E   I     +L  Y+ LL P HY+++ I   +  +Y  K     + +T  + E K + C S +  LG++DPGY++  G    E+    + +++       I + E  +++ 
Sbjct:  116 CFYCAKESDDQCECG-------EWMCGLEHALIHRPGKYCLPFKVCHSPEVGRYLVASRDIKPLELVLWDRAAAVGPAADALPVCLECFGKVDGSFLCPKCQFPLCGSKCVGKNLHKDECELFSKLEKKINFSNLTEKHPIYST---IAPLRLILLKKKNRLLWDSLCTLMDHNKERFASDPEMPKMFKLIVDFFLD-----EIKLDFVSS------EEVYHIIGVLLTNGFEND----HEGVQGRAIYPNLSLASHACRANLRHAVSPGYQVALQAQVPIQKGTELTIRYTHMLQGHLKRRKQISEVWFFDCSCIRCCDPTENGSLASAVICPKCKTGVILPIDSLDIHSMWRCSGCQEETDPKYIIDLEEMVDTEMEDVEGMDIAGYVTLLEKYKPLLPPTHYLMVIIKRYIQAIYGTKPGLELDNMTLTQLEDKAKFCRSFIRYLGKLDPGYSQHLGLSTIELSKVQLEIARRKSSEGEIDKLELVRQMK 1519          

Query:   84 CPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKN--NFVIKKENHYS-SQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCP----GVALYPVYCLINHACFNNTNYVKFPD-FHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHET-IDELEEMLYHYQK-LLHPNHYIVIDIMHNLIH--VYAAKETLTRPEKERK--IQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREF--HKRLNI-CARKLAEAKKCLT 563
            C +C +V YCSEEH+ +HR    CFP+   R    GR + A RDI PLEL+L +   VVGP  K  P CL C R+V+  + C  C  P+C + C  G  H+ EC    ++     +  +N  S   A VTPLRMLL+ +S    + + + LMDH+EE+ V   + +    +I+ FL++          ++  ++ F  ++I+  +G+L  N +  +      GCP    G   YP++ +++H C  N  Y   P+ F++ +R+++ I+ GE++  +Y+S+  G  RRR+ I++ W+FDC C+RC D TE GTY+S + C +C+ G +LP NSL+Y S+W+C  C   +    +  I+D IE+++  I + +   + ++ +  Y   +LHPNH+++     NL+    Y+  +     +++ K  + LC S  + L ++DPG+++      +E+ +  + + + D     +   EF    R +I   +K+ E KK +T
Sbjct:  193 CSYCNLVNYCSEEHFRLHRQDEYCFPYKSGRIPEKGRVLFATRDIKPLELVLIDPGTVVGPNYKSEPVCLQCLRIVETGFKCPTCQFPMCGQNCVEGVRHQQECEILSQDLERTKLTSQNIPSHGYAHVTPLRMLLLMESSGEKWLRTNQLMDHLEEKDVHPDEWSWYESHIVDFLRK----------DLKLASRFSNEDIKHAIGLLNVNAVCLQ-FPKMIGCPSTEVGKGCYPIFAIMSHHCICNARYFVDPNTFNMYVRARVNIQAGEELTVQYLSALNGTHRRRKKIREEWYFDCTCKRCSDPTECGTYISALKCINCQVGSMLPSNSLDYSSNWTCVKCHSEIECDKVECIVDYIENELNQITNSSDFQKYQDFIKEYSGIILHPNHFLLTTARRNLMQYLCYSPPDINKSDQQDLKFRVDLCKSFYDVLHKIDPGWSELGMFGQRELHFSRLSLLQRDFALGSVPFAEFSVKSRDSIQILKKIDEQKKIIT 1650          

Query:    1 MFCYPAFYDIIYLYVCVRSQRPQNSVHETFFPLVMSPAASSKDSNGASPINGLTDTQDDVEVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKKPIDEDNVSKSNT 592
            MFCYPAFYDIIYLYVCVRSQRPQNSVHETFFPLVMSPAASSKDSNGASPINGLTDTQDDVEVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKKPIDEDNVSKSNT
Sbjct:    1 MFCYPAFYDIIYLYVCVRSQRPQNSVHETFFPLVMSPAASSKDSNGASPINGLTDTQDDVEVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKKPIDEDNVSKSNT 592          

Query:   35 MSPAASSKDSNGASPINGLTDTQDDVEVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQ 206
            MSPAAS+KDSNG   ING+TDT++DV+V  DMCCFFCGNEEEEDNHLTLCPFCKIVYYCSE+H II+RH+NRCFPFIV++SKRFGRYM+AARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVD SY+CSKCGVPVCDKECEIGDLHRPEC YFQ NNFVIK E+ YSSQ
Sbjct:    1 MSPAASNKDSNGVLRINGMTDTKNDVDVYIDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEDHSIIYRHTNRCFPFIVRKSKRFGRYMIAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDDSYHCSKCGVPVCDKECEIGDLHRPECSYFQANNFVIKNEDRYSSQ 172          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSE-EHYIIH-----RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGS-YYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKI--DMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKE---FNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNL------IHVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEM 522
            CF+CGN          C  C++V +CSE  H  +H       ++ CFPF VKR+ + GR++VA RDI  LE+IL E P V+GPY      CL CF+ +D S + C  C  P C +EC  G  H+ EC  FQK     + EN     + +T LR+L +++S P  +  I  DML DH  +              I  +  E  +S E     + +  T  + D   + R++G++ TNG         +   G  LY +Y  +NH+C  NT  + F D  +E+R+ + I KGEQI  +YV      L RR  IK  W+FDC C+RC D TE G+Y+  + C  CK+  +LPIN L  ES+W+C  C    + + +  ++ ++   +        +  E++LY  Q LLHPNHY+ I+    +      I   +  + + RP  ERK Q C  +LE L  VDPG+ +WR  IL E+
Sbjct:    7 CFYCGNPATAS-----CTTCELVSFCSEPSHKALHYGHKKDETSFCFPFAVKRNSQLGRHLVATRDIKALEVILEESPLVIGPYISSNNQCLECFKTLDTSPHSCISCNYPFCSQECSQGPWHKIECSAFQKYGHK-RDENDNDFYSIITTLRLLSLQESKPEFWNTIMKDML-DHNSD--------------IQEYTPEKWTSYEETVVKKIQSLTKGNADTDTLTRLIGVIDTNGADLNLPHDGKHGKGTGLYLIYSNLNHSCVCNTKTINFQDRRIEMRASVNISKGEQICNQYVRPNKCTLARRTTIKNKWYFDCCCKRCADPTECGSYLGALLCSSCKS-VVLPINPLETESNWACKGCSKEYDVEYVMGVLISVGESLEEATPYDPNSYEKILYDTQDLLHPNHYLRIEAELKVAALIGNIPTSSFSKGMPRPAVERKRQCCFHILEVLSLVDPGFNQWRVQILSEL 457          

Query:   60 VEVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIH--RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKE----NHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA------AKETLTRPEKE--RKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILK 579
             E ++   C +C  +  +      C  C + +YCS EH  +H  +H NRC  + +  S+  GRY+ A RD+ P ELIL E P ++ P +   P CL+C+  VDG Y C  CG P+C++ C     H PEC    +    IK        +     V  LR L MK+     ++ +  L  H +ER+  N + +   + ++  ++E  S           S  F  ++I  + GIL  N  +     P    P  ALY    L+ H+C NN +     + ++ +R  IPIKKGE I   Y     G + R+Q + +  FF C C RC D TEL T+ S I C  C  G+L+ ++  NYESDW C  C+ +   + ++ +I +I  ++ S+E  + +     +  + + LHP+H+ ++D+   L  +          E     EK+  +K +LC  +LE   ++ PG ++ RG ++ E+       +++      I+       L    + L E  +  +   T L E  +++I +
Sbjct:    2 AEAESQFTCAYCQIQANQR-----CTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIK-NGKYSRDKMTMLRVIREFFSV---------PSTRFPDEDILALCGILFVNSHEV----PVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIAR 516          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIH--RHSNRC-----FPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNC---FRLVDGSYYCSKCGVPVCDKECEIGDLH-RPECGYFQKNNFVIKKENHYSSQ---ACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERV--VINKQVNIQ--LLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPE-RGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK--ETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL 562
            C  CG   +       C  CK V+YC  EH   H   HS  C      P+ ++R+ R GRY+VA  DI+   LI +E P V+GP       CL C    +    +Y C +C  P+C + C    +H   EC         +  +   ++    AC+T LR L +K  + + +++      H+ ER+   + +QVN +  +  I  FLK +S               F   EI    G L TN  +    G   RG     LY +  +++H C  NT +    ++ + + S + IKKGE I   Y       L RR+ +     F C C+RC D TE GTY+S  +C  C  G +LP++ L+ +S+W C  C   +   T+   I+++  +++SI+    + LE+ L  Y  LL   + +  +I   L+ ++  +  E L   +  RK  +C  +L    RVDPG++KWRG +L EM    +++ +      RI+  +     +   + L EA + L
Sbjct:  137 CIVCGELAK-----NFCSSCKYVFYCKREHQKSHWSSHSKECAHFKALPYRIERNPRLGRYLVAKDDISEGSLIFNEPPLVIGPRQLTKAVCLXCHNELKDKKDTYPCRRCTWPMCSRSCSDSPVHANAECSILSYGGVKVNIDAFGTANMMYACITVLRALSLK--NDHKWQEYLKFDSHLNERMPTQVYQQVNKEKVVFFIHYFLKLLSK--------------FSDLEILEACGKLDTNCFEIRQFGKNLRG-----LYRIGSIMSHECTPNTRHTFEENYDINVYSTVDIKKGEIICATYTQPLWCTLSRREHLNMSKCFWCRCKRCSDPTEFGTYLSAFSCSEC-GGKMLPLDPLDQKSNWKCEKCSHTLESTTVRHGIESMMDELKSIDRTNPENLEDFLKRYATLLPETNQLTREIQLGLVSLFKNRRNEDLKTTQLLRKAFMCRQLLTVANRVDPGFSKWRGELLLEMQSANVILGQRALAEGRISNIQAKDIFDENMKHLKEADRVL 625          

Query:   83 LCPFCKIVYYCSEEH---YIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDK-ECEIGDLH-RPECGYFQKNNF-----VIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINC--------KHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYH-YQKLLHPNHYIVIDIMHNLIHVYAAKE--TLTRPEKE-RKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVS 530
             C  C  V YCS+EH   + +  H N C  + + + +  GR ++  RDI P E+I  E P  VGP     P CL C++ V+G+  CS C  P+C   ECE   +H + EC      +      + K E        +T LR LL+K+  P+ +  ++ +  H E R    +   +  +NI+ F+ E                D   ++I + + ++  N   FE    E    G  LYP+  ++N  C  NT      ++   + +   I KG +I + Y  +  G L RR  +K+  +FDC+C+RC D TEL ++ S + C        K CK G++   NSLN  + W C  C  +++++ ++++   +E ++   E  TID+ E  L +   K LHPNHYI++D    L+   +  E     R ++E RK ++   +L+    + PGY + R  ++ E    +M ++
Sbjct:   39 FCSGCHSVGYCSKEHQKNHWLQGHKNECCAYKLVKKEGHGRILIVTRDIEPGEVIFEESPITVGPKQFCQPVCLGCYKNVNGTSICSGCNWPMCGNIECEKAPIHSKKECALLADCHLKPIIDLNKPEKDLPIYQFLTALRCLLVKEFRPDNWSILESMESHTELRKN-EESYRVNQVNIVKFILE------------RIKYDTTVEDINKCIDVMDVNA--FEIRSHEFSIAG--LYPMTAMMNSNCSPNTQNSIDENYICRVMAITRIPKGSEINSTYTRTLSGTLYRRNQLKESKYFDCKCERCCDPTELNSHFSTLLCQAILPSISKTCK-GFVYSENSLNTNASWICRACGAVMSHEEVTELTQKLEVEIEK-EFLTIDDYENFLKNRLLKFLHPNHYIIVDFKFILMKALSRAEYDPEIRIQREIRKKRIIEDILDVHSLITPGYFRIRAMLVSERCMVMMSIA 489          

Query:  100 IHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYY--CSKCGVPVCDKECEIGDLHRP-ECGYFQKNNFVIKKEN-------HYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERV--VINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKF-EPL--GPERGCPGVALYPVYCLINHACFNNT--NYV-KFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIE-HETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKE-----TLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVS 530
            I R  +   P+ + R+   GRYMVA RDI P E +L E P   GP +   P CL C+  V  + +  C  CG P+C KEC     H+  EC      NF +  +N         S    ++ +R L++KK DP  +  I M M H E R      ++ + + L  I  + ++S              D+D   I+ +LGI   N  +   PL    E+      ++ +  + NH+C +N   N+  +   F + +++ + IK+G++I   Y       +RR+  +K   FF C C RC D TE+ TY S + C  CK G ++  N  N  SDW C++CD+ ++  ++  +    +S++  ++ +  ++  E+ L  Y  + HPNH  +ID  + L  +Y   E     +L+  +  RK +LC  VL+ L  + PG T+ +G ++ E+  P +++ 
Sbjct:   21 IERDQSSNRPYKIIRNDSVGRYMVATRDIKPGETVLMEYPLTFGPGNPNEPICLGCYTPVLKNQHTECDGCGFPMCSKECSQILEHKDFECAEMHNMNFRLDSQNTLKWNGSQESVYNAISLMRALVLKKRDPARWNLIWMHMSHDEARQKDTFWQKKDAKTLEHIKAMMKISPE------------DYDT--IKIILGIFLVNDFEICIPLEGSDEKSSLIRGIFALASMPNHSCVSNCYHNFTCREEGFKMTMKAVVDIKEGDEITHSYTEPLDPIMRRQSLLKIGKFFQCNCIRCRDPTEMSTYSSALICSKCKKGNVISKNCKNINSDWECDSCDLTLSPDSVEQVNSKAKSEIEEMDKNPDVETHEQFLNKYATIFHPNHVYMIDRSYVLGKMYGRMEGYEPDSLSDDQFMRKKELCERVLKVLNVITPGQTRKKGMMMYELHLPFVIMG 461          

Query:   61 EVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPL--------------ELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHR----PECGYFQ--KNNFVIKKENHYSSQAC-VTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNN 418
            + + D  CF CG   +       C +C +VYYC + H+ +HR    CFPF + + K  G+ MVA RDI PL              ELIL +     GP +  +  C+ C + +D    C  C  P+CD+  +    H      EC   Q  KN  V++  +      C + PLR+LL++ ++P+ F +   LMDH EER   +   N     II FL++                DF ++EI+R  GI  TN       G      G A++P +  ++H+C +N ++  FP  HL L+S++ I  G ++   Y+S   G L+RR  ++  WFFDC C RC+D TELG+++S   C+ C    LLP + L  +S++  N 
Sbjct:   10 DANEDQLCFLCGTPSKNK-----CSYCDLVYYCGDPHFKLHRPEELCFPFKISQRKNVGQVMVATRDIEPLGTLHFTIKKTSIKTELILYDTTQAFGPKNSSIV-CIECLK-IDPKGNCKSCKWPICDENSKCQGKHLLHSLRECEILQTSKNKEVLENPSKLVDYVCAIXPLRLLLLRDTNPDEFERFQYLMDHNEERRKDDGIWNGYKKYIIDFLRD----------------DFKEEEIERASGIFWTNAFSCSXGG------GQAVFPTFSFVSHSCTSNCDHTVFPQRHLVLQSKVHIAAGTELNINYISPIQGRLKRRSKLRCKWFFDCICDRCLDATELGSHLSSHLCEFCGE-ILLPSDPLIMDSNYVLNG 358          

Query:  207 ACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRS-IEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETL-TRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL 562
            + + PLR+L +K  +P  + ++++LMDH+++     K +  + ++ IL              +      + + +I R LGI +TNG+       +    G  LYP +  I+H+C  N  +  F +  L LR+   I KGE+I   Y+       RRR  IK  W FDC C+RC D +E G+ +S ++CK C  G LLP  S + +S+W C+ C   V++ ++S+++   E  +   ++H+ + E++  +  + + L+PN+Y++  +   L+ V    +   TR + E+ + L   +L+ +  ++PG +  RG IL+++  P + ++K D +  +I  +EF        + +  A +CL
Sbjct:  300 SAIFPLRILKLKSKEPEVWSRVNLLMDHVDDLEKDMKSLYEKTVDFIL--------------DSCKLTKYTRSDILRALGIFRTNGVN------QGFSQGFGLYPTFSFISHSCSPNARFQIFENHSLVLRAIQNIPKGEEITISYLPIYQATFRRRIKIKNNWLFDCYCERCKDPSEFGSNLSAVSCKECITGILLPKISTDMKSEWKCSECKYEVSFSSLSNVMLVFEQNMELFLDHDPL-EIQFKIDSWTQTLNPNNYLIFLLNRRLLDVLCTNDNFETREDLEKVLLLARDILKIVDLIEPGLSTTRGRILKQIHKPSLKLAKNDLKDGKINSQEFLLITKDIIKNMKTAVRCL 636          

Query:   66 MCCFFCGNEEEEDNHLTLCPFCKI----VYYCSEEHYIIH---------RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCF------RLVDGSYYCSKCGVPVCDKE 176
            M CF C + E       +CP C      V  CS +H  +H         + +  C  F +      G  M+A++DI   +++  E+PAV GP SK  P CLNC       +L    Y+CSKCG PVC++E
Sbjct:    1 MPCFLCNSPESP----LVCPHCASSSSSVEACSNDHLKVHYSPKSIKKGKETESCSSFKIGTKPHIGNVMLASKDIRAGDVVFIERPAVWGPDSKSRPVCLNCLENKSSNQLEAERYFCSKCGFPVCNEE 126          

Query:   84 CPFCKIVYYCSEEHYI--IHRHSNRCFPFIVKRSKR-FGRYMVAARDINPLELILSEQPAVVGP---YSKKLPGCLNCFRLVDG--SYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEE-RVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEP-----LGPERGCPGV-ALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTI---ESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTR-PEKERKIQL-----CMSVLETLGRVDPGYTKWRGTILQEM 522
            C  C++V+YCS EH       H   C  + ++ ++   GR +  ARD+   +LI+S  P V+GP   Y K  P CL C  ++D   S     C  P+C  EC        EC   +K    IK  +       VT LR  L+KKS+P  + K+ +L DH++E +    +  NI+   ++  LKE+ S  +  +++          E++R++GI  TN  + E       G +R    +  LY V  L+NH+C  N   V     ++++ + +PI     I   Y+S      RR++ +K+  FF+C+C+RC D TELGT+ S + C+ CK     P        ++ C +C  +++ +    I +++   ++++  I    +  +   L  YQ +L   H  +I I   L+ +  +   +++  E  +KIQ+     C  VL     +DPG +  RG +L E+
Sbjct:   21 CGACELVWYCSREHQKRKWRDHKMICIAYRIEDTQSALGRQLRTARDVKQGDLIISAPPCVIGPRLDYPK--PSCLGCHVILDEKMSLCEGGCEYPLCSSECHRKFHSEEECKLLEK----IKSPDKRCE--IVTILRFALLKKSNPRIYEKLILLEDHVDEIKASSTRWKNIEE-GVLKHLKEIKSDLDIEEDQ----------ELERLVGIWITNSFELERTDQQLFGEKRAGESIQGLYDVPSLMNHSCVGNARLVINSGMYIDVYAAVPISNKAPITFNYISPLEDYDRRQKILKENKFFECKCERCEDPTELGTFSSSLLCQVCKKS---PSTRTKDSKNYECRDCSEVMSERDAMKIANSLMKGKNKLHRIGKAWVTCI-PFLKEYQDILWETHTFIIXIKMXLVXLXXSNXAISQMDENGKKIQIERQSYCNDVLAVQDIIDPGMSLGRGLVLHEL 460          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKK--LPGCLNCFR-LVDGSYYCS-KCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINK-QVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLEL-RSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKH--CKNGYLLPINSLNYESDWSCNNCDVIVNYKTISD----IIDTIESQVRSIEHETIDELEEMLYHYQKLLHP-----NHYIVIDIMHNLI 476
            + +  S   GR + A RDI   ELI  E+  V GP ++K  L  C+ C   L    + C  +C +PVC+  C   + H+ EC +F++     + ++  + Q  V P+ + ++          + +     E+R +++  Q N +      + +E+  + +  +N  +T   F   ++ R++G+L TN  +              L+P+  ++NH C  N ++  F +  L + R+   I KG +I T Y     GNL R   +K    F C+C RC D TE GTY+S + C+   C+ G ++P+ +   + DW C  C+ +  +  ++      ++TI +++ S        +++M+ H+   L P     ++Y++I+   N+I
Sbjct:   57 WTISSSTVAGRGVFATRDIAAGELIFQERALVTGPTARKGQLSSCICCHETLPQTGFLCRHRCTLPVCET-CSDSEEHQAECEHFRR----WQPKDVDAEQEQVNPMSLRILTA--------VRVFHLGKEQRHLVDAMQANAERA----YRREIIQAAQCFRNFPTTDRVF-MDQLFRIVGVLNTNAFEAPCRSGGHETLLRGLFPLTAIMNHECTPNASHY-FENGRLAVVRAARDIPKGGEITTTYTKILWGNLTRNIFLKMTKHFACDCVRCHDNTENGTYLSALFCREQGCR-GLVIPVQTRTLQPDWRCITCENVFPHAKMAKYQDFALNTINNRINSC------SVQDMI-HFINELCPRFCPSSNYVLIEAKLNVI 413          

Query:  119 GRYMVAARDINPLELILSEQPAVVGPYSKK---LPGCLNCFRLVDGS----YYC-SKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDML----MDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQI------PIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKH--CKNGYLLPINSLNYESDWSCNNCDVIVNYKTISD----IIDTIESQVRSIEHETIDELEEMLYHYQKLLHP-----NHYIVIDIMHNLI 476
            GR + A R+I   E +  E   +VGP + +   L  C  C+RL+ GS      C + CG+PVC  EC     H  EC  F+K                    + L  ++ +P   R + ++    +D    +++   Q N+       +++EV  + +  ++     +  D     R +    TN  +             AL+P+  L+NH C  N  +      H E    I       I  G +I   Y       L R+  +     F C+C RC D TE GTY+S + C+   C+ G ++P+ +   + DW C  C+ +  +  ++      ++TI +++ S        +++M+ H+   L P     ++Y++I+   N+I
Sbjct:   53 GRGIFATREIAAGEELFREHTLLVGPTAHRSMNLRTCTLCYRLIPGSTDSAALCPAGCGLPVCS-ECRDSTRHDLECKLFRK-------------------WKPLESQRIEPRALRILSVVRCFFLDEASRKLLYAMQANMDRY----YMQEVQRAADCFEHFPREQDMLDY--FYRTICAFNTNAFESRSNVDGHEVLVRALFPLAGLLNHQCTPNAAH------HFENGETIVVCATERIPAGAEITMSYAKLLWSTLARKIFLGMTKHFICKCVRCQDPTENGTYLSALFCREQGCR-GLVIPVQTRTLQPDWRCITCENVFPHAKMAKYQDFALNTINNRINSC------SVQDMI-HFINELCPRFCPSSNYVLIEAKLNVI 399          

Query:  119 GRYMVAARDINPLELILSEQPAVVGPYSKKLPG-CLNCFRLVDGSYYCSKCGVP-VCDKECEIGD--LHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPN----------TFRKIDMLMDH---IEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKF--EPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCID-----RTELGTYMSGINCKHCK-NGYLLPINSLNYESDWSCNNC----------DVIVNYKTISDIIDT---IESQVRSIE-HETIDELEEMLYH 456
            GR +  ARD  P E+ILS++P +  P +      C  CF+  +    CS C V   C   C+  +  LHR EC    +    ++KE        +  +  L +K++  N           +  ++ L+ H   I+E+ ++       L+N+IL    V                 D +EI         N        L P+    G+ L+P+  +INH+C  N   V F +    +R+   I K  +I   Y+ +    L R++ +K+ + F C+C RC +       E    + G  C + K  G+LL       E  + C  C           +  + KT+S+   T    E +  +IE ++TI++L+  LYH
Sbjct:   22 GRSLFTARDFRPGEVILSQKPYICVPNNTSSESRCDGCFK-TNNLKKCSACQVVWYCGSSCQKSEWKLHRDECKALTR----LEKEKRKFVTPTIRLMVRLYIKRNLQNEKVLPITTTDNYSLVEALVSHMSEIDEKQMLLYAQMANLVNLILQFPSV-----------------DLREIAENFSKFSCNAHSICDSELRPQ----GIGLFPLVSIINHSCSPNAVLV-FEEQMAVVRAMDNISKDSEITISYIETAGSTLTRQKSLKEQYLFHCQCARCSNFGKPHDIEESAILEGYRCANEKCTGFLLRDPE---EKGFVCQKCLLLRSKEEVKKLASDLKTVSEKAPTSPSAEDKQAAIELYKTIEKLQVKLYH 368          

Query:  112 VKRSKRFGRYMVAARDINPLELILS-EQPAVVGPYSKKLPGCLNCFR----LVDGSYYCSKCG-VPVCDKECEIGDLHRP---ECGYFQK---------NNFVIKK--------------------ENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVV--INKQVNIQLLNIILFLKEVSSSKEFNQNEV-STSNDFDQKEIQRMLG------ILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRT----ELGTYMSGINC--KHCKNGY----LLPI-NSL--NYESDWSCNNCDVI 422
            +K S+  GRY++A RDI   E +L  +    V   + K   C NC +    ++  S  C++C  +  C+++C+  ++++    EC +++K          NF I+                      N +  Q            +   NT   +D + D +E +V    N     ++ +I+ F+ E+ +          S  N+ D+ E+ R +       I KT   +F        C GVA+ P     NH+C  N   V+    ++  +S  PIKKG+Q+   Y+        R+ ++K  ++FDC C RC   +     +  ++S   C  K C   Y    ++PI N+L  N+E   SC+NC+ I
Sbjct:   10 LKSSENEGRYLIATRDIQIGEDLLKCKSYFAVTSETLKTTSCFNCIKQLPSVIKLSLKCNQCNEIWYCNEQCKNENINKHQHYECKFYKKLKSPKLKVYPNFDIETFTEIRMIVGLLSRYYQDILLNNKFIEQQLNNNNNNNNDNEQLTNT---LDDVFDLVENQVTEESNPAAKERIDSIVEFISELFNLVLLGSTTTKSIINNDDKIEMIRKINEKSRSIIHKTRCNQFGIWTKNDKCIGVAVSPSSSYFNHSCIPNCTDVR-DGSNMTFKSLYPIKKGDQLTISYIELDQPIQDRKDELKYGYYFDCICPRCNGDSNSIDSMDNWISKFYCSQKKCTGLYYSKPMIPILNTLTSNHEIQLSCSNCNNI 376          

Query:  119 GRYMVAARDINPLELILSEQPAVVGPYSKKLPG-CLNCFRLVDGSYYCSKCGVP-VCDKECEIGDL--HRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRK-----IDMLMDHIEERVVINKQVNIQL-LNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERG--CPGVALYPVYCLINHAC-------FNNTNYVKFPD-FH----LELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRC 379
            GR + A ++    ++I +E+      +   +   C  CF+  +  + C +C     CD+ C+      H+ EC         IKK     ++      R++   + +     +     +D L +H+E      ++   +L +++  FL          Q     S  F  + I  + G++  NG     L  +RG    GV ++P   L+NH C       FNN N+      FH    +ELR+   I +GE++   Y+     +  RR+ +K+ ++FDC C+ C
Sbjct:   18 GRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECA-------AIKKYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEH---FGEEEQKELRVDVDTFL----------QYWPPQSQQFSMQYISHIFGVINCNGF---TLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHC 279          

Query:  119 GRYMVAARDINPLELILSEQPAVVGPYSKKLPG--CLNCFRLVDGSYYCSKCGVPV-CDKECEIGD--LHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDF--------DQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRC 379
            GR + A R     EL+ S  PA     +    G  C  CF   +G   C KC     C+ +C+ GD  +H+ EC     ++     +N   S+      R+L  +K+   T R          ER +  K+    L  +       +  KE  +N++S  + F        D   ++ +   +  NG   E    E    G A++P   L+NH+C  N   V +     E+R+   I  GE++FT Y+        R   +K  +FF C+C+ C
Sbjct:   16 GRGLKATRSFALGELLFS-CPAYTYVLTDNERGNHCDFCFTRKEGLSKCGKCKQAFYCNVDCQKGDWPMHKLEC-----SSMCSSGQNWCPSETVRLTARILAKQKT--QTERTAS-------ERFMSVKEFESHLSKLD------NEKKELIENDISALHRFYSKNVHNCDNAALEFLFAQVNCNGFTIE--DEELSHLGSAIFPDVALMNHSCCPNV-IVTYKGTVAEVRAVQEIHAGEEVFTSYIDLLYPTEDRNDRLKDSYFFSCDCREC 265          

Query:  119 GRYMVAARDINPLELILS-EQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPV-CDKECEIGD--LHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDF--------DQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDR 382
            GR + A R  +  +L+ S    A V    ++   C  CF   +G   C +C     CD EC+  D  LH+ EC     ++ V+  EN   S+      R+L  +K  P              ER    K + ++     L  K  +  K+  Q++++  + F        D   +  +   +  NG   E    E    G A++P   L+NH+C  N   V +     E+R+   I  G+++FT Y+        R   ++  +FF CEC+ C  +
Sbjct:   18 GRGLRALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDVECQKEDWPLHKLEC-----SSMVVFGENWNPSETVRLTARILAKQKMHP--------------ERTPSEKLLAVREFESHLD-KLDNEKKDLIQSDIAALHQFYSKHLEFPDHSSLVVLFAQVNCNGFTIE--DEELSHLGSAIFPDVALMNHSCCPNV-IVTYKGTLAEVRAVQEIHPGDEVFTSYIDLLYPTEDRNDRLRDSYFFTCECRECTTK 270          

Query:  119 GRYMVAARDINPLELILS-EQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPV-CDKECEIGD--LHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDF--------DQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDR 382
            GR + A R  +  +L+ S    A V    ++   C  CF   +G   C +C     CD EC+  D  LH+ EC     ++ V+  EN   S+      R+L  +K  P              ER    K + ++     L  K  +  K+  Q++++  + F        D   +  +   +  NG   E    E    G A++P   L+NH+C  N   V +     E+R+   I  G+++FT Y+        R   ++  +FF CEC+ C  +
Sbjct:   18 GRGLRALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDVECQKEDWPLHKLEC-----SSMVVLGENWNPSETVRLTARILAKQKIHP--------------ERTPSEKLLAVREFESHLD-KLDNEKKDLIQSDIAALHQFYSKYLEFPDHSSLVVLFAQVNCNGFTIE--DEELSHLGSAIFPDVALMNHSCCPNV-IVTYKGTLAEVRAVQEIHPGDEVFTSYIDLLYPTEDRNDRLRDSYFFTCECRECTTK 270          

Query:  119 GRYMVAARDINPLELILSEQPAVVGPYSKKLPG-CLNCFRLVDGSYYCSKCGVP-VCDKECEIGDL--HRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRK-----IDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERG--CPGVALYPVYCLINHAC-------FNNTNYVKFPD-FH----LELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRC 379
            GR + A ++    ++I +E+      +   +   C  CF+  +  + C +C     CD+ C+      H+ EC         IK+     ++      R++   + +     +     +D L +H+E      +Q ++++ ++  FL          Q     S  F  + I  + G++  NG     L  +RG    GV ++P   L+NH C       FNN N+      FH    +ELR+   I +GE++   Y+     +  R++ +K+ ++FDC C+ C
Sbjct:   18 GRGLKATKEFWAADIIFAERAYSAVVFDSLVNFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECS-------AIKRYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVE-HFGEEEQKDLRV-DVDTFL----------QYWPPQSQQFSMQYISHIFGVINCNGF---TLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHC 279          

Query:  152 CLNCFRLVDGSYYCSKCGVPV-CDKECEIGD--LHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDF--------DQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDR 382
            C  CF   +G   C +C     C+ EC+  D  +H+ EC     +  V+  EN   S+      R+L  +K  P              ER    K + ++     L  K  +  K+  Q++++  + F        D   +  +   +  NG   E    E    G A++P   L+NH+C  N   V +     E+R+   IK GE++FT Y+        R   ++  +FF CECQ C  +
Sbjct:   52 CEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLEC-----SPMVVFGENWNPSETVRLTARILAKQKIHP--------------ERTPSEKLLAVKEFESHLD-KLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIE--DEELSHLGSAIFPDVALMNHSCCPNV-IVTYKGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTK 270          

Query:   83 LCPFCKIVYYCSEEHYIIHR--HSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVD-----GSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNY-ESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKE-----TLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHE 535
            +C  C  + YCS+EH   H   H + C P+ +   ++FGR + A++++ P E+I  E   + GP     P CL C+  +D       + C  C  P C ++C     H  EC    +    I   + +     + P   +L   +D    R+ DM                I  +N++ FL+++             +++F ++EI    G++  N  +    G +     + ++P+  +++H C  NT +V   ++ + +R+ +PI KGEQIFT Y     G   RR  ++    F+C+C RC D TE  TY+S + C +C NG +LP   L+  E+DW C+ C   +    ++ +ID ++ ++ +IE + +++ E+ L  +  LLHPNH+++     +L  +Y   E     TLT  + ERK+ +C  +L     ++PG T+ RG  + EM  PL++++K   E
Sbjct:   20 ICGGCGEISYCSKEHQKEHWLVHKSLCKPYKIVHDEKFGRCIFASKNLKPGEIIFGETAVITGPKQGCTPCCLKCYASLDRVQEASLFRCPNCNFPFCQEQCAKSPEHEAECLILSRAKSCIVINDVHR----IHPEYKMLENHNDLR--RQSDMW--------------RIYQVNVVQFLRKI----------CGLADEFSEEEIHASCGVIDVNAFEIRLAGNQYQ-QVLGVFPLASMMSHNCVANTQHVIDANYTMTVRASVPIMKGEQIFTSYTLPLEGTKERRDVLRHSKLFECDCSRCSDPTECSTYLSALRCPNCSNGVVLPERPLDEPETDWQCSQCPYKLTAAVVTQVIDKLKEELETIEPDQVEKFEDFLSRHASLLHPNHFLLTRARQSLSILYGRNERFLLNTLTSQQLERKVSICRQLLSVADIIEPGLTRIRGVTMYEMYAPLLLLAKRSFE 454          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRP-ECGYFQ----KNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRK-IDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGV---ALYPVYCLINHACFNNTNY-VKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEH----ETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPE-----KERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL 562
            F +KR+++ GR+ VA+R + P +LI +E P   GP S   P CL CF  VD +  CS C  PVC  ECE    HR  ECG F     K   V    N      C+TPLR+LLMK+ DP  +++ I+ +  H + R           +NI+ +LK       F    + T           + GIL+ N  +       R   G     L+P   +++H C +N ++ V    F + + + + + +  ++F+ Y  S    L RR+ +K+  +F+C C RC D+TELGT++  + C  C NG +L  + L++  +W C +C+   +   +  + + +++++ ++E     E I++ E +   Y+ + HP +  +  +  +L  +Y   E  T  +      ERK++LC  +LE L  V+PG+++ RG  L E+  PL+++++  +    I + +F K++      L +A + L
Sbjct:    5 FTIKRNEKVGRFAVASRALKPGDLIFTETPFAYGPKSDSPPLCLGCFAPVDCTVLCSHCSWPVCGPECEAKPSHRDFECGVFASAGVKFQAVEDPTNVCLQYECITPLRVLLMKEKDPKRWQEEIEAMESHNDVRKT-KPIWEFNQVNIVDYLKGPCKLDRFADELIHT-----------VCGILEINAFE------ARASSGYLIRCLFPKLAILSHNCVSNVHHSVDCDTFQVSVSASVEVPESGELFSSYTYSLWPTLVRREFLKESKYFECMCDRCKDKTELGTHLGTLKCNKCDNGVILSTDPLSFTCEWKCTHCEFKTSAIAVRKVYEAVQTEIDAVEMLSGPEGIEQREAIFRKYRSVFHPKNAYMTILRTSLSQLYGRAEGYTVEDLPDLLLERKVELCNQLLEVLDVVEPGHSRIRGVTLYELHAPLLILARNQYTSGMIDKEQFRKKMEEAVEILGKAVEIL 458          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCF----RLVDGSYYCSKCGVPVCDKECEIGDLHRP-ECGYFQKNN--FVIKK------ENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFP-DFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIE-------HETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK-----ETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL 562
            + + ++ + GRYMVA +++   E I++E P +VGP +   P CL+C+      ++    CSKCG PVC  ECE    H+  EC  F + N  F ++       EN      C+TPLR+LL  + +P  ++     M+   +     KQ     +NI+ ++++    + F++           ++IQ + GIL+ N   FE +   +G    A+YP   L+NH+C +NT +   P D+ + LR+ + I  G +++  Y  S +  + RR+ + +   F C C RC D TELGT+MS + C  C NG +L ++SL+ ES W C +C+   +   +  ++  I+ +V ++E        + I E E +   Y+ +LHP H  +  + H+L  +Y        E L     E KI +C  +L+ L  ++PGY++ RG  L E+  PL+  +K     + I +     ++   ++ L EA   L
Sbjct:   19 YKILQNDKVGRYMVANKELEAGEEIITEMPFIVGPKAATYPLCLSCYVSWPPTLNEKPLCSKCGWPVCSTECENQPQHKDYECQIFAQANEKFNVQAALEETNENGVPQLECITPLRLLLESEKNPERWKNEVKDMEAHNKIRSQKKQWKSDQINIVEYIRKQLKLERFSE-----------EQIQTVCGILEIN--TFE-VRTAKGFSARAIYPTVALMNHSCISNTCHSISPTDYKIRLRTTLKIPVGGELYGSYTHSLLPTMLRREHLLEGKNFACACARCSDPTELGTHMSSLKCNKCDNGIVLSLDSLDPESSWKCTHCEFSTSGSAVRKVLQIIQMEVDAVEAISGADGADAIQERETVAKKYRSVLHPRHAFLTMLRHSLTQMYGRVEDYLLEDLPDVVLEHKIDMCRLLLQVLDVIEPGYSRIRGMTLYELHAPLLFTAKTQWNAEVIDKAALKSKMIEASKILKEAATIL 483          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIH---RHSNRCFP-FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRL--VDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQAC-------------VTPLRMLLMK-KSDPNTFRKIDMLMDHIEERVVINKQV-NIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKF-PDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHC---------KNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHY----QKLLHPNHYIVIDIMHNLIHVYAAKETLTRPE-----KERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRL 548
            C  CG         ++C  CK ++YCS+EH  +H    H   C   + ++++ R GRY++A+ +I+  ++I  E P +VGP +  +P CL C  +  +D  + C  CG P+C  +C++ D H  EC    K+N+ IK ++                    + PLR +L+K K +   ++KI  L  H ++R  INK + ++   N+  F++E               +D D+KEI  + GIL TN   FE +       G  LY V  +++H C  NT +    PD  + + +   IK GE I   Y  +    L RR+ +K    FDC C+RC D +ELGTY   I C  C         +N Y++P++ LN  S W C NC   +++K I    D +++++     +T+  LEE L  Y      +LH N+Y V+ + H LI +    +  T  +      +RKI  C  +L+ +  VDP Y+  RG IL E+   +++ +K  +   +IT++E    L
Sbjct:    5 CAVCGQPSS-----SICGGCKRLFYCSKEHQKLHWMKEHKGCCRAVYKLEQNDRLGRYLIASENISKGDVIFYESPLIVGPKTVTVPVCLGCHNVCNMDNYHECDGCGFPLCSPQCQVSDNHVDECYQMMKSNYRIKMDSKKKKNNDDNNGGGKEIFYFPIVPLRCILLKGKKNSEKYKKIMNLESHYDDR--INKPLFDLYKKNVADFIRERLKM-----------DDVDEKEILTITGILDTNA--FEIVKNNVKLRG--LYNVSSMLSHDCKPNTKHSFLQPDMTIVVTATRDIKSGELITATYTQTFWNTLSRREHLKTIKCFDCVCERCSDPSELGTYAGAIRCSKCTMTSDKNSVENCYVIPVDPLNSNSVWKCMNCQREMSHKQIKMGNDNLKNELTKSNVKTVTGLEEFLIKYGVYENGVLHSNNYHVVQVKHALIRLIGNTDGYTYSDISDDLLDRKIIYCQELLDFVDVVDPEYSNIRGEILNELQSSIVVQTKRQYNNDKITKQEAQSNL 503          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKC--GVPVCDKECE-IGDL---HRPECGYFQ--KNNFVIKKENHYSSQA---CVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVI------NKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYV-KFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNY----KTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA----------AKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEA 558
            F VK SK  GRYMV+ +++ P ++ILSE P V+GP +     CL C++ ++ S+ C+KC  G P+C  +C+ +G      + EC   +  K++  +  +N    +     + PLR LL+K++D  +++ +  +  H E R  I      N++  +  + I   L+E                 + Q+EI  + GIL+ N  +      ++G     LYP   L++H C  NTN++ +   F L +R+   I+ GE I   Y  +    L+RR+ + +  FF+C+C+RC D TELGT+ S + C  CK+G++L  N L+ E+DW+C+N +    Y    K++  ++D I  +V +I+   +  +E  L  Y+ +LHP HYI + +  +L  +Y           + E LT     RK+++C  +++    ++PG+T+ RG  L EM  PLM++     E +  T+ E   +L    + L EA
Sbjct:   40 FEVKTSKVMGRYMVSRKNLKPGDVILSEAPLVIGPCTGCKVQCLGCYKTLESSF-CTKCTCGWPLCSPKCKGLGKRFGHSQVECAVLKATKSSKFLNYDNFEEMRPNFNAIVPLRCLLLKETDARSYQHLMTMETHNEIRRNIPELWQTNQRTVVDKIRIDWGLRE-----------------YSQEEIHSVCGILEVNSFEI----GQQGVNIRGLYPSAFLMSHDCVPNTNHIDEESTFRLTVRASTRIEPGEMITLSYAYTLQSTLKRREHLLENKFFECQCRRCSDPTELGTFTSALICPKCKDGFVLSSNPLDPEADWTCSNYNKCPGYKISAKSMQLLLDKITQEVDNIDCNDVITMETFLKKYRNVLHPTHYINLSVKLSLSQLYGRINGFLIDELSDEVLT-----RKLEICEEIIKVFNVIEPGFTRLRGVTLYEMHAPLMVLLTRQFE-RHCTKSELRSKLKKVLKCLEEA 492          

Query:   84 CPFCKIVYYCSEEHYIIH--RHSNRCFP-FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHR-PECGYFQKNNFVIKKENHYSSQA-------CVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLG--PERGCPGVALYPVYCLINHACFNNTNYVKFP-DFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDE---LEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK-----ETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEM 522
            C  C+ VYYCS EH       H   C P F +K S+  GRY+VA+R I   E+IL E P VVGP    LP CL C++ +  +Y CS+C  P+C   CE   LH+  EC             NH S  A       C+TPLR L +  SD     ++D L+ H+E+R  ++          I  L E + S       + T   +D + IQR+ GIL+TN  +    G    RG     LYP   L+NH C  NT +V  P DF + + +   I  G++I   Y  S    L RR  +K    F C+C RC D  ELGT +S + C  C  G +L  N L   S+W C++C  +   + +  + D+   +++ I     +    LE+ +  Y   +HP+   VI+  + L+ +Y          L+    ERK+  C  +L+    ++PG ++ RG +L E+
Sbjct:   12 CSKCRRVYYCSREHQKADWTNHKTLCGPPFKIKESEAEGRYLVASRLIKAGEVILQELPLVVGPKLNTLPLCLGCYKSITDTYRCSRCNWPLCSAACEESALHKNGECRMIDPTLMT----NHLSQGAINSQVFQCITPLRYLTLPDSDRE---RLDELVSHLEQRRGMD----------IYRLVEQNISSFLRYRLLLT--QYDSESIQRVCGILETNCFEIRIQGRVSVRG-----LYPTASLMNHDCVANTRHVFDPADFRIRILATKDIPAGDKISATYTRSLWNTLDRRLHLKSTKHFWCQCSRCADPRELGTLLSAVKCTGC-GGAVLSQNPLYQMSNWECSDCGSVQKVEQVKRVHDSARMELKQIAQLARNRPELLEDFIRKYSGAIHPDSCHVIEAKYALVQLYGNTPQLLYHDLSEELIERKLDYCRQLLKLADVIEPGLSQLRGHLLFEL 447          

Query:  111 IVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFR---LVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNF--VIKKENHYSSQAC-VTPLRMLLMKKSDPNTFRKIDMLMDHIE--ERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVST------SNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPD-FHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGY-LLPINSLNYESDWSCNNCDVIVNYKTISDII---DTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK-----ETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITE 541
            +VKR +  GR +VA RDI   E+I    P +VGP     P CL C +   L +  Y CSKC  P+C + CE   LH  EC  F K  +   +K +N   +  C + PLR LL+KK+ P  F  +     H++  E+  + + +   L+     L ++ +    N++E+ T      +N F+ ++ QR++ I              RG     LYP    ++H+C +NT +    D F L L +  PIKKG+ + T Y  +  G L RR  +K    FDC C+RC D TE GTY+S +NC  C +G  +   + LN E+DW C NC   +   T SD++   + ++ ++  +  +  + LEE L  Y ++LH  +   + + + L  +Y +      E L+    +RKI+LC  +L     ++PG + +RG +L ++   L  V+K +   + I E
Sbjct:    1 MVKRDEVLGRCVVATRDIRSGEVIAESLPLIVGPKMASPPLCLGCHKKLALAESRYDCSKCFWPLCGQACESSPLHEAECEIFAKAGYKPTVKNDNSKQTVYCPIAPLRALLLKKNSPERFNLLLDFQSHLQDHEKTQVYQVLKKSLVPFFTQLLKLDT----NESEILTICSIFDTNCFEVRDTQRLVNI--------------RG-----LYPTISFLSHSCKHNTKHCFNGDNFRLVLTATTPIKKGDLVTTTYTQTLWGTLSRRSHLKMAKHFDCLCERCTDPTEFGTYLSAVNCSVCGDGSKVTSSDPLNCEADWFCENCGFAI---TGSDMLWGNEVLQKEINHLNKDNPNSLEEFLERYAEVLHGRNSYCLQVKYALCQIYGSLDGFKFEELSSDLIDRKIELCKELLAVAEVLEPGQSWFRGLLLYDLFEAL--VAKAERRGEDIDE 427          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRP-ECGYFQKNNFVIKK----ENHYSSQACVTPLRMLLMKKSDPNTFR-KIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPER-GCPGVALYPVYCLINHACFNNTNYVKFPDFH-------LELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEH-----ETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA-AKE----TLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKL 555
            F + ++ +FGRY VA +D  P +LI+ E P   GP S   P CL C R VDG   CS CG PVCD++CE   +H   EC  F        K    + +     C+TPLR+LL K+  P  +  +I  L  H EER   +    ++ +N + FL +V   +E           F    I    GIL+TN        P   G     LYP   L  H+C  N  +  F + +       + +R+ + IKKG++    Y  +    L RR  +K+  FFDC CQRC D TEL T  S I C +C NG++L  + L  ++ W+C +C+  +   ++S +   I+ +V ++       + ++  E  +  Y+ LLHPN+  +I + ++L  +Y  AKE     L     E+K++LC ++ E L  + PG ++ RG  L E+   ++  +K+      I E++ ++++++  + L
Sbjct:    8 FDILKNDKFGRYAVALQDYEPGDLIIQESPFTYGPKSDSPPVCLGCHRKVDGKILCSTCGWPVCDEKCEKEPIHSENECIIFSSVKVRFTKVKNPQGNCPQYECITPLRVLLGKEKFPEIWNSQISKLESHNEERQKTDIW-KVESINTVGFLHKVCKLQE----------RFSSDLIHFACGILETNAFS----SPSSYGYDMRYLYPKSSLFLHSCIPNVGHYIFKNSNDGERSNVIHVRASLKIKKGQEFTLSYTQTLWPTLLRRSHLKEGKFFDCCCQRCSDPTELKTNFSTIKCSNCYNGWILNTDPLVVDAPWNCTSCNWKLTGDSVSKLFSNIQQEVENLNKLDNYLDPVEIRENFIKKYKSLLHPNNGFLIIVKYSLAQLYGQAKEYFLDDLPDILLEKKLKLCYTLDEVLKTLRPGISRQRGWNLFELQSCVVKFAKKQFRRNEINEKQLNEKISMAIKYL 462          

Query:  108 FPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYS-KKLPGCLNCFRLV-----DGSYYCSKCGV-PVCDKECEIGDLHRP--ECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEER--VVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLL---PINSLNY--ESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKERKI-----QLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKKPIDE 584
              + V  S++ GRY+ A++D+   E+IL E P  VGP S  K P C  C  ++     D +Y CS C V  +C   CE   ++    EC    KNN  +  EN       +  LR+ L+K+ DP  ++++  L  H+ +R   ++ +   I ++N++        S  F +N+ S S     + IQ++ GIL  N  +    G   G     LY    ++ H C  N +     +FHL + + IPIK+G+ IF  Y SS +G   RR+ ++   +F+CEC  C D  E+G+YMS I C  C+ GY+    P+    Y   + W CN C  I++   I   +   ++ V  ++   I  +E +     K LH NH++++ +   L++VY  ++ +T P  +RKI      LC  + + L  V+PG ++ +G +L E+  PL +++  ++  + I+  E  KRL      L   KK LT    +  E     + K+ + E
Sbjct:   15 LKYKVAYSEKLGRYLQASKDLRAGEVILREDPVAVGPMSCVKDPICFECLSILPNIEEDVNYVCSGCNVVTLCGVTCEERGIYHSAYECEII-KNNEELSIENTDVLAGVLFVLRLWLLKQKDPELWKRVLSLESHLNKRRNTIVWEDREINIVNVL-------KSLNFLENDPSVS-----EMIQQLCGILDVNSFELRSPGGMDGLLLRGLYLEASMMAHDCRGNVHVTADDNFHLTVYASIPIKEGDTIFFNYTSSLLGTTGRREYLRTGKYFECECDLCKDPYEMGSYMSCIVCPRCRQGYVGMQDPLTKFPYTKSAKWQCNKCKKIISGCLIKTSLSISKNLVDDVDEYNIKVMENLKDKLSKSLHKNHFLMLSLKQKLLNVY--RQEITGPNPKRKIMRSMVHLCKEMFDLLEIVEPGISRLKGIMLYEIHLPLALLANREYNAREISSGELAKRLEEAGSFL---KKSLTMLLLEPVETPEGKLAKRALQE 494          

Query:   83 LCPFCKIVYYCSEEHYIIH---RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLV------DGSYY-CSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIK-------KENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA-----AKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEM 522
            LC  C+ V YCS EH   H    H + C  F +  ++  GR++ A RDI   E IL E P V+GP     P CL C R +       G+Y+ CS C  P+C KECE    H+ EC     +NF  K       +E   S+   +  LR + +K  DP+ F K+  L DH++ER+       +   N+I F+K V   K           D+ + +I R+  IL TN   FE   P       ALYP   +I+H C  N  +    D ++   ++  I KGE +   Y       ++RR  ++Q   FDC C RC D  ELG++     C  CK G ++ +N L   + W C  C+   + K +      ++ ++ S++  T   LEE +Y ++  LH  +  ++   + L  +Y      A E L+     RK+QLC  +L+     D G++ +RG +L +M
Sbjct:   19 LCAACRNVVYCSREHQKEHWKKGHRSECQCFEIATNEVLGRHLRATRDIKIGEQILKEAPLVLGPKVASAPLCLGCHRNLLAPGKPRGNYHKCSSCSWPLCGKECEDSVHHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDPDAFLKLYNLEDHLKERLE-TPLYQVLRANLITFIKTVLGMK-----------DWPEMDILRIAAILDTN--TFEVRQPRERRKIRALYPGAAMISHDCVPNMRHRFDDDMNIVFLAKRKIAKGEILSISYTQPLRSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLKCKAGKIISLNPLLNSAPWKCQLCNFKRSAKDVVTSDAELQQELESLDKTTPVALEEFIYRHRADLHETNTHILQAKYALTQLYGSAPGFAMEELSGESLNRKLQLCEELLKLADIFDGGWSIFRGNLLIDM 466          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSE-EHYIIH-----RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGS-YYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKI--DMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKE---FNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNL------IHVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEM 522
            CF+CGN          C  C +V +CSE  H  +H       ++ CFPF VKR+ + GR++VA RDI  LE+IL E P V+GPY      CL CF+ +D S + C  C  P C +EC  G  H+ EC  FQK     + EN     + +T LR+L +++S P  +  I  DML DH  +              I  +  E  +S E     + +  T  + D   + R++G++ TNG         +   G  LY +Y  +NH+C  NT  + F D  +E+R+ + I KGEQI  +YV      L RR  IK  W+FDC C+RC D TE G+Y+  + C  CK+  +LPIN L  ES+W+C  C    + + +  ++ ++   +        +  E++LY  Q LLHPNHY+ I+    +      I   +  + + RP  ERK Q C  +LE L  VDPG+ +WR  IL E+
Sbjct:    7 CFYCGNPATAS-----CTTCGLVSFCSEPSHKALHYGHKKDETSFCFPFAVKRNSQLGRHLVATRDIKALEVILEESPLVIGPYISSNNQCLECFKTLDTSPHSCISCNYPFCSQECSQGPWHKIECSAFQKYGHK-RDENDNDFYSIITTLRLLSLQESKPEFWNTIMKDML-DHNSD--------------IQEYTPEKWTSYEETVVKKIQSLTKGNADTDTLTRLIGVIDTNGADLNLPHDGKHGKGTGLYLIYSNLNHSCVCNTKTINFQDRRIEMRASVNISKGEQICNQYVRPNKCTLARRTTIKNKWYFDCCCKRCADPTECGSYLGALLCSSCKS-VVLPINPLETESNWACKGCSKEYDVEYVMGVLISVGESLEEATPYDPNSYEKILYDTQDLLHPNHYLRIEAELKVAALIGNIPTSSFSKGMPRPAVERKRQCCFHILEVLSLVDPGFNQWRVQILSEL 457          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNF---VIKKENHYSSQA-CVTPLRMLLMKKSDPNTF-RKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFP--DFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHET-----IDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPE-----KERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKKPIDEDNVS 588
            F +++    GRY VA  D+ P ++IL+E+  VVGP +  +P CL CF  VD SY CSKC  PVC  ECE    H PEC  F   N    V      YS Q  CVTPLR+LL  +S+   +  ++  +  HIE R       N Q  N++ FL+E    + F+++ + T+            GIL+ N  +       +G  G  L+P   L++H C +NT +   P  ++ L LR+ + +KKGE++FT Y  S +  + RR+++    +F C C RC D TEL T+MS + C  C NG ++  + L+ E++W+C +C   +  + +  I   I++++  +  E      I+ +E++L  Y+ +LHP H  +  + H+L  +Y   E  T  +      ERK++LC  +L  L  ++PGY++ RG IL E+  P+M+ ++  ++Y  I +    ++L   A+ L EA   L+     + E  V+ + ++ + +  VS
Sbjct:    5 FKIEKKDTVGRYAVATCDLKPSDVILTEEAFVVGPKATTVPVCLGCFVPVDCSYLCSKCTWPVCSPECESSPYHAPECQIFSAANAKYQVPADLFEYSPQLDCVTPLRLLLASESNSKRWNEEVKDMEAHIEARKKTPYWENEQT-NVVKFLRERCKLERFSEDLIHTA-----------CGILEVNAFEVRS---SQGYTGRGLFPKTALMSHNCVSNTCHSIVPSKNYKLILRATVDVKKGEELFTSYTQSLLPTMVRRENLLDSKYFHCACPRCSDPTELNTHMSSLKCTKCDNGIIISTDPLDAEAEWTCTHCQFKLRGEQVRRIYRVIQTEIDGMPGEEGTPERIEAIEKLLKQYRSVLHPKHAYLTILRHSLSELYGRAEGYTFEDLPDILLERKVELCQQILSVLDVIEPGYSRMRGMILYELHVPMMLFARSRYQYGEIDDATLRRKLEEVAKILEEAVAILSLEDPTMGEGIVAQMAQESLGQLRVS 485          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNF---VIKKENHYSSQA-CVTPLRMLLMKKSDPNTF-RKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFP--DFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHET-----IDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPE-----KERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKKPIDEDNVS 588
            F +++    GRY VA  D+ P ++IL+E+  VVGP +  +P CL CF  VD SY CSKC  PVC  ECE    H PEC  F   N    V      YS Q  CVTPLR+LL  +S+   +  ++  +  HIE R       N Q  N++ FL+E    + F+++ + T+            GIL+ N  +       +G  G  L+P   L++H C +NT +   P  ++ L LR+ + +KKGE++FT Y  S +  + RR+++    +F C C RC D TEL T+MS + C  C NG ++  + L+ E++W+C +C   +  + +  I   I++++  +  E      I+ +E++L  Y+ +LHP H  +  + H+L  +Y   E  T  +      ERK++LC  +L  L  ++PGY++ RG IL E+  P+M+ ++  ++Y  I +    ++L   A+ L EA   L+     + E  V+ + ++ + +   S
Sbjct:    5 FKIEKKDTVGRYAVATCDLKPSDVILTEEAFVVGPKATTVPVCLGCFVPVDCSYLCSKCTWPVCSPECESSPYHAPECQIFSAANAKYQVPADLFEYSPQLDCVTPLRLLLASESNSKRWNEEVKDMEAHIEARKKTPYWENEQT-NVVKFLRERCKLERFSEDLIHTA-----------CGILEVNAFEVRS---SQGYTGRGLFPKTALMSHNCVSNTCHSIVPSKNYKLILRATVDVKKGEELFTSYTQSLLPTMVRRENLLDSKYFHCACPRCSDPTELNTHMSSLKCTKCDNGIIISTDPLDAEAEWTCTHCQFKLRGEQVRRIYRVIQTEIDGMPGEEGTPERIEAIEKLLKQYRSVLHPKHAYLTILRHSLSELYGRAEGYTFEDLPDILLERKVELCQQILSVLDVIEPGYSRMRGMILYELHVPMMLFARSRYQYGEIDDATLRRKLEEVAKILEEAVAILSLEDPTMGEGIVAQMAQESLSQLRAS 485          

Query:  103 HSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGS---YYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQA---CVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPD-FHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNY-ESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKE-----TLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSI 577
            H   C P+ +  +++FGR +VA R++ P E+I  E   +VGP     P CL CF  +D     + C  C  P C ++C     H  EC    +    I   +   S     C+TPLR +L+K + P  F     L+ H + R    +   I  +NI+ FL+ V             +N F ++EI    G+L  N  +    G +R    + L+P+  +++H C +NT++V   + + + +R+ +PIKKGEQ+FT Y     G   RR  ++Q   F+C+C RC D TE  T++S + C  C  G +LPI  L   E++W C+ C   ++   ++ +ID ++ +  +I  + +++LEE L  +   LHPNH++   +  +L  +Y   E     TLT  + ERK+ +C  +L     V+PG T+ RG  L E+  P+++++K  +E    T  EF +R+      L+EA K L       TE +  ++
Sbjct:   42 HKTSCKPYKIVSNEKFGRCLVATRNLKPGEIIFGENATIVGPKQGCRPCCLKCFTSLDSVASLFRCPGCNFPFCQEQCAKSPEHEAECVVLSRARSCISINDMSKSHPVYQCITPLRCILLKSTQPKLFEAFSGLVHHNDLRRQ-TQMWRIYQVNIVQFLRNV----------CGLANQFSEEEIHAACGVLDVNAFEIRLPGSKRQ-QVLGLFPIASMMSHRCVSNTHHVIDSNTYEMTVRASVPIKKGEQLFTTYTLPLDGTNDRRSVLRQSKMFECDCPRCSDPTECLTFLSALRCPRCPIGIMLPIRPLEENETEWQCSPCSYQLDAADVTQLIDQLKEEFENIGPKDVEKLEEFLSRHASSLHPNHFLFTSVRQSLSQLYGRDERYLLNTLTMEQLERKVSICQQLLSVADVVEPGLTRLRGVTLYELYAPMLLLAKRTYEAGHCTLAEFKERIVAVEAILSEATKILLLEDPASTEGAACAV 517          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHR-PECGYFQKNNFVIKKE------NHYSSQACVTPLRMLLMKKSDPNTFR-KIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFP--DFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIE-----HETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPE-----KERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLT 563
            + +KR+++ GRY++A+RD+   + +L E P VVGP S   P CL C+  +DGS  CS CG PVC +EC   + H+  EC  F       ++E      N      C+TPLRMLL K+ +P+ ++ +ID +  H +ER     +   + +N++ FL++          +   +  F +  I  ++G L+ N  +      E G     LYP   +++H C  NT +  +P  +F  ++R  + + +G ++F  Y SS    + RR++++   +FDC+C RC D TELGT++S + C  C +G ++  + LN E+ W C +C+  +  +T+  I   I+S+V  ++        I E E ML  Y+ +LHP+H  +  + H+L+ +Y      T  +      ERK+ LC  VL+    V PG  ++RG +L E+  PLM+ ++  +EY  + + EF  ++   A  L EA   L+
Sbjct:    5 YTIKRNEKVGRYVLASRDLKAGDEVLVEYPFVVGPKSGSPPVCLGCYCPIDGSVVCSACGWPVCGEECATLEPHKGSECAVFAAAGVRYQQEAEEEDTNGSPQYECITPLRMLLNKEKEPDRWQAEIDEMEAHTDERKA-QSEWKTEQINVVEFLRK----------KCKLAERFSEDIIHFVIGALEVNAFEVRT---ENGFFVRGLYPQTAIMSHNCVANTTHTIYPAENFRSQVRVTVDVVEGGELFVSYTSSIQPTILRRENLRYSKYFDCDCPRCSDPTELGTHLSTLKCTKCDDGLIMSSDPLNQEATWKCTHCEFTIRPETLRKIFRMIQSEVEQMDLIEEFDAKILESERMLKKYKSVLHPHHVYMTSLRHSLVQLYGRAPGYTFQDLPDILLERKVDLCRLVLKVADVVKPGMNRFRGMVLYELHVPLMLYNRNRYEYGELKKEEFKSKMEEVANILEEAVNILS 464          

Query:  103 HSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGS---YYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQA---CVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYV-KFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNY-ESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKE-----TLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKK 580
            H   C P+ +  +++FGR +VA R++ P E+I  E   +VGP     P CL CF  +D     + C  C  P C ++C     H  EC    +    I   +   S     C+TPLR +L+K + P  F     L+ H + R    +   I  +NI+ FL+ V             +N F ++EI    G+L  N  +    G +R    + L+P+  +++H C +NT++V     + + +R+ +PIKKGEQ+FT Y     G   RR  ++Q   F+C+C RC D TE  T++S + C  C  G +LPI  L   E++W C+ C   ++   ++ +ID ++ +  +I  + +++LEE L  +   LHPNH++   +  +L  +Y   E     TLT  + ERK+ +C  +L     V+PG T+ RG  L E+  P+++++K  +E    T  EF +R+      L+EA K L       TE +  +  KK
Sbjct:   42 HKTSCKPYKIVFNEKFGRCLVATRNLKPGEIIFGENATIVGPKQGCRPCCLKCFTSLDSVASLFRCPGCNFPFCQEQCAKSPEHEAECVVLSRARSCISINDMSKSHPVYQCITPLRGILLKNTQPKLFEAFSGLVHHNDLRRQ-TQMWRIYQVNIVQFLRNV----------CGLANQFSEEEIHAACGVLDVNAFEIRLPGSKRQ-QILGLFPIASMMSHRCVSNTHHVIDSKTYEMTVRASVPIKKGEQLFTTYTLPLDGTNDRRSVLRQSKMFECDCPRCSDPTECLTFLSALRCPRCPIGIMLPIRPLEENETEWQCSPCSYQLDAAVVTQLIDQLKEEFENIGPKDVEKLEEFLSRHASSLHPNHFLFTSVRQSLSQLYGRDERYLLNTLTMEQLERKVSICQQLLSVADVVEPGLTRLRGVTLYELYAPMLLLAKRTYEAGHCTLEEFKERIVAVEAILSEATKILLLEDPASTEGAACAKKKK 520          

Query:   84 CPFCKIVYYCSEEHYIIHR--HSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFR---LVDGS--YYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFV----IKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNT-NYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCK------NGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPE-----KERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITE 541
            C  C +V+YCS EH   H   H  +C P+ V+ S+R G ++VA RDI   E+I+ E+P V+GP    LP CL C R   +++G   Y CS CG P+C   CE    H PEC   ++  F     +K++   ++   +TPLR LL+KK D + +  I  +  H++ER       NI   N++ FL+      EF++           + I R+  IL TN   FE    E       LY    +++H C  NT ++ + P + L+L S +PIKKGE I   Y  +  G L RR  +KQ   FDC C RC D TELGTY+  INC  CK      N  L+  + L   + W C  C   +  + ++   D I  ++ +++      LE+ L  Y+  LHP +  ++++ + L  +Y   +     E      ERKI LC  +LE    +DPG T+ RG +L ++   +++ +K D    +IT+
Sbjct:   28 CSSCHLVFYCSREHQKQHWKIHKTQCTPYKVEVSERLGHHVVATRDIQQGEVIIEEEPIVLGPKVLSLPLCLGCGRRIKVIEGEEVYKCSGCGWPLCGSHCETSPFHVPECNLMKERGFRADINLKEDKKEAAYCSITPLRCLLLKKHDQSKYEGIVKMQSHLKERR-DTPLYNIFKNNVVGFLRNALGMTEFSE-----------ETILRITAILDTNS--FEIRRSEGDIKVRGLYSKAAMLSHDCKPNTKHFFRGPKYTLKLVSTVPIKKGEIICVTYTQTLWGTLERRAHLKQSKCFDCTCLRCSDATELGTYIGAINCSQCKKSGGKRNDKLISTSPLEPSAPWKCEVCSHTIPGRQMAWGNDAIRREISALDKSKPQGLEDFLDKYKGALHPANGHILEVKYALSQMYGNMQGFLLSELPDRLLERKINLCTELLEIADVLDPGSTRLRGVLLYDLQATMVVQAKRDLASDKITK 494          

Query:   84 CPFCKIVYYCSEEHYIIHR--HSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRP-ECGYFQKNNFVIKKENHYSS----QACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYV--KFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYES-DWSCNNC-DVIVNYKTISDII----------------------------DTIESQVRSIEHETIDELEEMLYHYQ-KLLHPNHYIVIDIMHNLIHVY--------AAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL 562
            C  C  + YCS EH   H   H N C  F VKR++  GRY+VA RDI    +I +E+P   GP     P CL+C + VDGSY CSKC  P+C +ECE   LH   EC  FQ+   V  + +++ S      C+TPLR LL+K+ +   + K+  +  H E R  +    N   +N++  L E    KE          D+D++ I  +LG +  N  + +    E+      +Y    L++H C  NT++      D  + +RS IPIKKGE I T Y +   G   RR  +K+  +FDC C RC DRTE  TY+SG+ C  C  GYLLP   L   S DW C N  DV     +IS+ I                              +E   RS     +  LE +L  Y  K+LHPNH I+++++ NL + Y         +K  +      R   LCM +L  L  +DPG T+ RG  L ++  P   +++   + K I  +E+   +      L  +K+ L
Sbjct:   32 CSGCHSISYCSSEHQKKHWKIHKNDCRMFAVKRNEMLGRYLVATRDIPQGTVIFTEEPLTTGPKRCTYPVCLSCCKRVDGSYRCSKCTYPMCSEECEQNPLHAENECIIFQRGLPVGSRISNFDSICPAYECITPLRCLLLKERNSCKWEKLTTMEHHNELRKSVPGLWNRNFVNVVKLLLEWYKMKE----------DYDEEAINSVLGYIDVNCFEIKYKDVEK----CGMYRDGALMSHECVPNTHHAISMSEDHKMIVRSSIPIKKGEMITTSYANQLSGTRERRIFLKETKYFDCMCGRCEDRTEFATYLSGVKCTDCATGYLLPKEPLCANSTDWVCTNSPDVQAQAPSISNGILSSSKPSGIICNKTMKEEQIHTILKKAHKDVEESRRSTSGSVVSRLERILKKYSGKILHPNHSILLEVIKNLNYTYVKMYDDPEGSKNDIDLDRLIRSKTLCMQLLSVLDMLDPGLTRLRGVTLYQLSTPDFQIARSKFQKKEIDIQEYKAAIEKVLAYLQTSKEIL 544          

Query:  110 FIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQA----CVTPLRMLLMKKSDPNTF-RKIDMLMDHIEER----VVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGV-ALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCN--NCDVIVNYKTISDIIDTIESQVRSIEH-----ETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPE-----KERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILKKPIDEDNVS 588
            + +++++++GRY+VA +D+   +LI ++ P  VGP     P CL C+  V+ S  CS+CG P+C  ECE    H  EC  F       +    +++      C+TPLRMLL K+ DP+ + R ++ +  H E R         QVNI                +F  +     + +D+  +QR+ GIL+ N ++     P RG   V A+YP   +  H+C  N  +  F +  +++R+ +PIK G  +   Y  +    L RRQ + +  FF+C C RC D TELGT++S + C  C NG +L  + L+ E+ W C   NC+   +   +S I+  +++++  ++      + I++ E  L  Y+ + HP H ++++I H L  +Y   E  +  E      ERK + C  VL+TL  + PG ++ RG +L E+  P+M +++ ++    IT  +  +RL    + LA+A + L     +  E     I ++ +++   S
Sbjct:    9 YDIQQNEKYGRYLVANKDLESGDLIFTDTPFAVGPKPDSPPLCLGCYNPVENSL-CSRCGWPICGAECEASAAHAGECEVFANAKVRFQPVEDWTASTPQLDCITPLRMLLAKEKDPDRWQRDLEPMETHTEARKEKPAWAADQVNI---------------ADFLVDHCKLGSKYDKDLVQRVCGILEVNSVEI----PSRGGFSVRAIYPRLAIAAHSCVPNIVHTIFQEDMVKVRATVPIKSGSALLLCYTHALSPTLVRRQYLLESKFFNCTCARCADPTELGTHLSTLKCTKCDNGVILSTDPLDNEAQWKCTDKNCEFKTSGAAVSKILAVVQAEIDQLDMMEPSPQAIEQREATLKKYKSVFHPRHSLLLNIKHALAQLYGRVEGYSIDELPDLMLERKAEFCKLVLQTLDVITPGDSRMRGMMLYELHAPIMFMARNEYSAGLITPEKLKERLQEPIQHLADAARILMREDPQSPEGITGQIAQQSMEQLKAS 489          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIH--RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGS----------YYCSKCGVPVCDKECEIGDLHRPECGYFQKNNF--------VIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQV-NIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYV-KFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHY---QKLLHPNHYIVIDIMHNLIHVYA-AKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITERE 543
            C  CG E +      LC  C  +YYC  EH   H   H   C  F ++ S   GRY+VA RDI   E+IL E+P V+GP    LP CL C R +  +          Y CSKCG P+C   CE    HR EC    + N+          KKE+ Y    C+TPLR LL+ + +   F+++  L  H++ER  IN  +  I   N+++F++EV   K+F           D++ I  + GIL TN   FE            LYP   +++H C  NT +V    DF L L + + IKK E I   Y  +    L RR  +K    FDC C+RC D TE  T++S I C  CKN Y++    LN  +DW C +C  I   K IS   D ++ +++S++  +  +LE  L  Y     +LH N+  V++  + L  +Y      L+  +   KI LC  +LE    ++PG TK RG +L +M   + +++K+  E ++IT  +
Sbjct:    5 CATCGEEAK-----LLCSGCHSLYYCGREHQKKHWKTHKPECTTFRLEYSPTMGRYVVANRDIKQGEIILKEKPIVLGPKIASLPVCLGCNRRLKATAMDDDDPLEYYKCSKCGWPLCAPRCEDSPNHRDECKLMSERNYRSPIQYQDSPKKESSY---CCITPLRCLLLPQKE---FQRLSGLQSHLDER--INTPLYKILKTNLVMFIREVLGLKQF-----------DERTILNVAGILDTNA--FEIRRNMGNVKIRGLYPRTAMLSHNCKPNTKHVFAGEDFELSLMATVDIKKDEIISATYTQTLWPTLDRRAHLKMSKCFDCSCERCADATEFNTFLSAIKCSKCKN-YVISTEPLNRLADWQCTSCSKIFTAKQISLGNDALKKELQSLDKSSPSQLEHFLESYLTFDGVLHENNCHVLEAKYALCQIYGNMLSELSDDQLTNKINLCNDILEVANILEPGITKLRGVLLYDMQAAMAVLTKKLLESEKITAAQ 479          

Query:  113 KRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRP-ECGYFQKN---NFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQ 438
            KR +   R+MVA RDI  LE+IL EQPAV+GPY+++  GCL CF+ V   Y C +C +PVCD +C+ G LH+  EC +FQ         +      SQ CVTPLRMLL +  DP  F +IDMLMDH           N + L  +  LK +   ++  Q       +F Q EIQRM+GIL+TNGMK E  G E G PGVALYP+Y LINHAC NNTNYVK+ D H+ELRSQ+ I KG++IFTRY+SST+GN+RRR++I++ WFF C+C RC+D TE GT+MS + C  C++GYLLP ++ + ESDW C+ C+ I+ ++ ++++I T+E+Q
Sbjct:  164 KRGRLHPRFMVATRDIEALEMILWEQPAVIGPYTREAQGCLQCFQKVSSPYTCQRCNLPVCDAKCQDGTLHKDNECQFFQAGVTEGGQARGTGTVPSQICVTPLRMLLKRARDPKVFAQIDMLMDHA---------TNGKDLLTLSTLKVICMIRDQRQG-----TNFAQSEIQRMIGILRTNGMKLEQRG-EDGTPGVALYPIYSLINHACSNNTNYVKYSDRHMELRSQVAIGKGQEIFTRYISSTLGNVRRREEIERNWFFRCQCPRCLDPTEFGTFMSAVRCFQCQSGYLLPSDAQDLESDWKCDRCEWIILHQKVNEVITTLETQ 478          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIHRHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDG-SYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVI------KKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKH--------CKNGYLLPINSLNYESD---WSCNNCDVIVNYKTISDIIDTIESQVRSIEH-ETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKERKIQ-LCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLT 563
            CF CG    +     +C  C +V +CS++H  +HR    CFPF +      GR MVA+RDI PLELIL +     GP     P CL C + +    + C KC  P+C ++C  G  H  EC    +N   +         +HY S   + PLR LL++ S P  + +   LMDH  ER    +   +    +  FL+E          +   ++ F  +EI R  G+  TN       G      G A++P +  ++H+C +N N+V FP+ HL L+++I IKKGE++   Y+S     LRRR  ++  W+F+C C RC+D TE GTY++ + C          C+   ++ I  L  E     WSC+ C   ++  ++  + + +  +++ IE+   +   E++   ++  LHPNH++++ +  ++I +          E+ +K Q LC  VL  L ++DPGY + RG IL  +     +  ++    + I+   F++++  C     E++KC++
Sbjct:    8 CFLCGEPATQ-----VCQDCNLVKFCSDDHRQVHRPEKLCFPFKILHDPIKGRCMVASRDIQPLELILYDHTMAYGPKMGSPPVCLQCLKPIRNLDHPCPKCSWPMCSQKCAQGKTHELECSSLAQNTAKVDFGNFHATHDHYRS---IAPLRFLLLRDSHPKFYDQFQYLMDHNVERKKDTETWELYQKYVNDFLRE----------DCELADRFSNEEIDRACGLYWTNAFACNSGG------GQAIFPTFSFMSHSCVSNANHVVFPNKHLALQAKILIKKGEELTISYISPLQSTLRRRAKLRDKWYFECNCSRCLDPTEKGTYLASLKCGANLANSKGPCQG--VMCIEELANEPSQVFWSCSKCSNRISGDSVLQLENVVAKELQDIENRRDVGLYEQVQTKFEVQLHPNHFLLVLLKRHIIALGCEDIYDLELEQLKKFQALCEQVLNVLNKLDPGYNRDRGLILGHLANVKKLTCRKMFHNELISHDVFNRQVAECMILFGESQKCMS 497          

Query:  119 GRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVI------KKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVS---STIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK---ETLTRPEK--ERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEA 558
            GRYMVA R+I P E+I ++QPA VGP +   P CL CFR V+GSY C  C  P+C + C     HR EC  FQK   V+      K  ++Y +   + P+R+L +K  +P  +  + +LMDH       N Q++       L +K      +F +       DF ++E+  +LGIL  N         E     + LYP   +++H C +NT      DF     +   I++GE+I T Y        G   RR+D+K  W F+C CQRC D TE GT +S + C+ CK GYLLPI   ++ES W CN+C   V +  +   +   E ++ +I+   +  LE++L   + +LH NHY ++D+   L+ ++  K   E    P++  E KI  C  +LE   ++ PG ++ RG +L +     M +S+      RI   ++ ++L     KL E 
Sbjct:   52 GRYMVAKRNIYPGEVIFTDQPACVGPDNSSKPLCLGCFRKVNGSYKCPGCRWPMCCESCTRLPGHRAECTIFQKRKAVVNVPWFDKPCSYYDA---ILPMRILFLKWFNPKVYHLVTLLMDH-------NDQLDE------LTIKHRQRIIDFIRKTCRLGKDFSEEEVNHVLGILTVNSFVVHDT-EEDNLDLIGLYPWTSIMSHNCVSNTKITTREDFSYVCHATTFIREGEEIVTSYHHYHYQLYGTAYRRKDLKNTWSFECLCQRCQDPTEAGTMVSAVLCEGCKEGYLLPITPHDFESSWRCNHCFSHVPHGDVEAKVKKFEDELDTIKSSDVVSLEKLLRRMKYVLHENHYWILDVKRRLVDIWGNKPGFEVYKLPKEILENKIDFCDHLLEVTTKLSPGPSELRGYLLWQSHNVTMRLSQWKWIRMRINTLQYIEQLKALTGKLKEV 488          

Query:  122 MVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRL---VDGSYYCSKCGVPVCDKECEIGDLH--RPECGYFQKNNFVIKK-------------------ENH--YSSQAC------VTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQV-NIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHET--IDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK-----ETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLN 549
            +VA+RD+  +E++L E P V+GPY K    CL CF+    V  ++ C  C  P+C +EC    L+  + EC      N  I+K                   E H    S AC      +T LR L +K+  P  +  I  L+DH  E         N+ +  +I  LK+                  +++E  R LGI  TN      L    G  G +LYP +  INH C  NT  +K  D  L++R+  PI+KG++I  +YV        RR  ++  W+F+C+C RC D TELG+Y+S   C  CK+G +L  + L+ ES W C +C        +   ++ I + + S   +T  I   EE L+ +   LHP H I  D+   L  +Y         + +RP  +RKIQ C  VL+T GRVDPG++ WR  IL E+    + +++ D     I E +  + L 
Sbjct:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPG--------------INEQEALRFLGIGVTNNAN---LNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILG 451          

Query:   68 CFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIH--RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQA-----CVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHC---KNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVID--------IMHNLIHVYAAKETL----TRPEKER--KIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSI--LKKPIDEDNVSKSNT 592
            C FC  +  +      C  C + +YCS EH   H  +H   C  F +  S   GR++VA RD+ P EL+LSE P ++ P +  +P CL CF+ VDGS  C+ CG P+C   C     H PEC         I  E   +S        +  LR + +K+S+P+ F K+  L  H E+R     ++N ++    + LK +   + FN +    S+D    E+  + GIL  N  +  P+ P    P +ALY    LI H C +N +     D  L++R+ + I+KG+ I   Y     GN  R+Q + +  FF C C RC D  ELGT  S + C  C    NGYL  IN L+  S +SC++C    +   ++ +I +I  ++  +E    +     +  + + LH NH+ ++D        I  NL  V     T+    TR EK+   K +LCM ++     + PG ++ RG IL E+   L + +++    K IT   F   +    R L E  +  +     + E  ++S+  LK    ED +S  +T
Sbjct:   12 CAFCNGDANQR-----CTGCHVTFYCSREHQKQHWKKHKTNCCAFKICSSSVIGRHVVATRDLRPGELVLSENPLLIAPMAYTVPICLACFKPVDGSIRCTTCGWPMCSDLCIGSSNHVPECTLNNSRGKPIPDEVGSNSVPNPIYEAIATLRCIYLKQSNPDVFEKLMQLEAHAEKR-----KLNGRVDKDQIILKMI--RRFFNISASLISDD----EVLDLQGILFVNSHEV-PVTPT---PVLALYLNSSLIEHNCVSNASKHFDTDGSLQIRAAVHIRKGDHIAITYSDPMWGNANRQQHLMESKFFQCICNRCQDPLELGTNFSSLRCPSCPAQANGYLSSINPLDIHSPFSCDHCHCEESADYVNAVIRSIGEELVQLEKGNPEACLTFIKKHSQNLHRNHFYLMDVKLALCQLIGKNLDTVEDQSNTVMDFRTR-EKDLIIKQKLCMELISIANIISPGISRLRGVILYELQSTLAIYARKKFAAKEITLDHFKNIIQEVRRYLIECIQIFSFESECIQEGRLASVARLKLAEVEDQLSSFDT 541          

Query:  119 GRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKEC-EIGDLHRPECGYFQKN--NFVIKKENHYSSQ-----------ACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFE-PLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQR 378
            GR+MVA RDI PLELIL + PAV GP     P CL C   VDGS+ C  CG+P+C ++C +    H  ECG        + +K +    SQ            C+TPLR+L +KK+D   + ++ MLMDH E+R       N+  +N + FL+++               D+ ++EI R  GI++TN    E P     G  G A++P +  ++H+C  N  Y    D  L LR+Q  I  G +I  +Y+S   G+L+R+ +I+  WFF C C+R
Sbjct:  422 GRFMVATRDIQPLELILEDSPAVFGPNHDTEPICLECLVPVDGSFLCPICGLPLCGEKCFQAAKYHPAECGLLSNTPKGYRMKVDFSRVSQRPNAKVIAPEYCCITPLRLLALKKTDAELWSRVQMLMDHDEDRRKEEDYWNMFQINAVDFLRKICGF------------DYSEEEIFRATGIIRTNAFHVEHPYMKLHGTSGGAVFPTFSFLSHSCVANAKYSVSSDNRLSLRAQDQIPAGSEISIQYLSFMFGDLKRKSEIRDCWFFQCLCRR 684          

Query:   84 CPFCKIVYYCSEEHYI--IHRHSNRCF-PFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGP-YSKKLPGCLNCFRLVD--GSYYCSKCGVPVCDKECEIGDLHRP-ECGYFQK------NNFVIKKENHYSSQAC-------VTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCK---NGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDEL------EEMLYHYQKLLHPNHYIVIDIMHNLI--------HVYAAKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLM 527
            C  C +V+YC +EH       H   C  PF +K  +  GRYMVAARD+   ++IL E+P ++GP   +    C+ C+R++   G   C  C VPVC  +C   + HR  ECG  ++      + +  ++  H SS +        + PLR LL+KK D   ++K   L  H+  R     +VN       L         +F  +E +     ++  +Q++ GI  TN       G  RG  G  LY    ++ H+C  NT  V   D  + + ++ PI KG+ I   Y         RR  +     F CEC RC D TE+G+  S   C +      G +L    L+  + W+C +C       ++S+I+ T E ++R +E + +  L      E+ L  +  LLHP H ++++    L         H YA    LT  + +RK+QLC  VL TL  ++ G     G    E+ + L+
Sbjct:   35 CSACFLVFYCQQEHQKSDWKAHKKICAKPFQIKDDEIVGRYMVAARDLQAGQVILREKPCLLGPNLEESDLICVVCYRVLTPRGFLTCKLCQVPVCSVQCSQSESHREGECGVLKQKPLGFYSTWTNRELVHRSSPSAEHANFQLIIPLRALLLKKRDVQQYKKFMALESHVSAREGTQAEVNTDERVCRLL-------DQFRMHEAA-----NRDLVQKICGIFDTNSFDLAIQGGGRGITG--LYLNAAMMMHSCVKNTRLVFSHDHVMTIYAREPIHKGDPIHHSYTRVLAPTTLRRTLLFVGKHFSCECVRCKDPTEMGSLASAWLCPNSGCGPEGVVLSETPLDLSAPWTCRHCS--ETPYSVSEILLT-ERRLR-MEMDRLKPLACVPAWEDFLERHASLLHPQHALLVEAKQTLSVGYGRFQGHFYA---QLTPSQVQRKVQLCREVLATLRLLESGLAAEIGLATYELAFALI 494          

Query:   90 VYYCSEEHYIIHRH-SNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLL--NIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMK-FEPLGPERGCPGVALYPVYCLINHACFNNTNYV--KFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCK-NGYLLPINSLNYESDWSC--NNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRPEKE---RKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCL----TGGFTKLTENSVSSILKK 580
            +++C   H   HR     C P  V   K  GR   A RDI   E+I +E P VVGP +   P CL           C+K  VP      +  DL           N+ +           + PLR  L+  SDP+    +  LMDH      + K+ N Q+   N    +  ++S  E           F   ++ R +G+++ N  + + PL     C    ++P+  L++H+C  N  +   +   +     + + I +GE+I   YV   + +  RR  +K+ W+FDC C+RC+D TELGT + GI C+ C  +G+LLP +S++Y S W C  ++C   ++ +  S  ++ + ++   ++ + I      L    + LH NHY++  +   ++ +Y    T +   +E    K+ L    L  L  ++PG T+ RG  L E+    + +     +   +   +F   L  C  +  EA +CL     G F     ++ SS++++
Sbjct:  458 IWFCRPGHGNYHRKLDGSCSPMKVASQKDVGRCTFATRDIKAGEVIFNENPIVVGPNNVTTPQCL----------VCTKKLVP------KKSDL-----------NYEL-----------ILPLR--LITHSDPDVRSLMATLMDH-----RVEKEANAQVWEHNRQSMVDPLTSILE---------GHFTSDDVIRAVGVVEVNNFEIYNPLD----CGFRGIFPLTSLMSHSCTPNARHAIGRSAPWSSVCIASVDIPRGEEITITYVPLILCSSERRAKLKENWYFDCRCRRCLDPTELGTNLGGILCQACSPSGFLLPADSIDYNSKWICSRSDCQAELSAEECSQKVERLLTEKDHLDRKDIPGFLTFLQRAGEELHVNHYVLNSLRRWIVSLYCKSSTCSTITEEMLRSKVHLATLYLSVLNTIEPGLTRNRGRALYELAEAQLAILSLQLKSGSLDGTDFLGTLEECLERAQEAAQCLEHDTEGSFEAYIRHASSSLIQQ 906          

Query:  112 VKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLH-RPECGYFQKNNFVIKKENHYSSQA-----CVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNT----NYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDT----IESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA-----AKETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKR----ITEREFHKRLNICARKL 555
            V       R+++A    +   ++ +E+P +VGP     P CL C+  VDGS  C +CG P+CD  C+  D H + EC  FQ     I  +     Q       + PLR+ +MK  DP+  R    L  H++         +               +K       + S +  ++E+ R+ GIL TN   F    P        +Y    + +++C  N       ++   F + LR+++PI++GE +   YV + I    R++ ++    F C+C RC D TELGT+ S +NC     G ++ ++ +     + C  C  ++    +  I+       E+ + S   ET++  E  L  Y++LLHPN+ +++ I + L  +         E+LT  +  RK +LC   L+ L  +DPG +  RG I  E+    +M+++ ++   +    + + EF   L    + L
Sbjct:   25 VTTGSSSARHVLAKSKWDQGVILWTEKPILVGPRYSTTPVCLGCYGTVDGSCLCQRCGWPLCDNACQYLDQHSQWECELFQSKGIKIDGKKLKYDQTEVMYDIILPLRVWIMKTKDPDQARDFFELESHVDTWTNTPAWRD-------------GHTKVLGYLNDTLSLNVSEEELSRIFGILYTN--DFSVDNPSGSVKITTVYKDVSMCSNSCIPNAIRSIGSIQ-EGFQITLRAKVPIQEGEGVTIAYVDNMIPTPIRQEHLQYGKHFTCQCPRCSDPTELGTHGSSLNCGQECGGEVV-LDPVQDRGAFKCQKCGRVMAKDIVGKIMTKAYHETEALLASSGSETVELCEMFLTKYRRLLHPNNILMLRIKYGLSTMLGRVSGYLMESLTPVQVIRKRKLCEESLQVLDVLDPGLSSKRGLIHYELHIAQIMIAQLEYSSGKMDVLLAKEEFESSLKSLEKAL 474          

Query:   38 AASSKDSNGASPINGLTDTQDDVEVDNDMCCFFCGNEEEEDNHLT--LCPFCKIVYYCSEEHYIIH--RHSNRC-----FPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFR-LVD--GSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQ---ACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCN--NCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRP 488
            +++SK    A P       + D +   D  C  CG       HL    C  CK V+YC+ EH   H   H   C      P+ V+R+   GR++VA  DI      L+E P V+GP     P CL C + LVD      CS+C  P+C ++CE   LH PEC   +     +  E+        AC+T LR L ++      ++       H+++R+       +    ++ F+             +   N +   EI    G L TN  + +    + G    A+Y V C+I+H C  NT +   PD  + L +   I+KG  I   Y  S    + RR  +     F C+C+RC D TE GTY+S  +C  C  G ++P   L+  + W+      +  ++  T+ DI       +R I   +  +L E L   +K    N Y V     +  +V   + TL  P
Sbjct:  200 SSTSKSQANADPNFEEGKPKSDGKPQGD--CEICG-------HLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYF----------LKLINKYSDLEILETCGRLDTNCFEIK----QNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC-GGQVIPTQPLDNSAKWALQLEGNEAELDKLTMDDIF-----ALRIITGTSDFKLREELLRQEKATKENFYKVAITWESAANV---QRTLAHP 635