EMLSAG00000007374, EMLSAG00000007374-690140 (gene) Lepeophtheirus salmonis
Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:Egfr "Epidermal growth factor receptor" species:7227 "Drosophila melanogaster" [GO:0005006 "epidermal growth factor-activated receptor activity" evidence=ISS;TAS] [GO:0008071 "maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded" evidence=IMP] [GO:0048749 "compound eye development" evidence=IMP] [GO:0007390 "germ-band shortening" evidence=IMP;TAS] [GO:0005886 "plasma membrane" evidence=IDA;TAS] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=TAS] [GO:0016333 "morphogenesis of follicular epithelium" evidence=IMP] [GO:0008586 "imaginal disc-derived wing vein morphogenesis" evidence=IMP;TAS] [GO:0001752 "compound eye photoreceptor fate commitment" evidence=TAS] [GO:0001709 "cell fate determination" evidence=TAS] [GO:0061331 "epithelial cell proliferation involved in Malpighian tubule morphogenesis" evidence=IMP] [GO:0007314 "oocyte anterior/posterior axis specification" evidence=NAS] [GO:0007310 "oocyte dorsal/ventral axis specification" evidence=NAS] [GO:2001234 "negative regulation of apoptotic signaling pathway" evidence=IGI] [GO:0007391 "dorsal closure" evidence=IMP] [GO:0007431 "salivary gland development" evidence=IMP] [GO:0007443 "Malpighian tubule morphogenesis" evidence=IMP;TAS] [GO:0002009 "morphogenesis of an epithelium" evidence=IMP] [GO:0009952 "anterior/posterior pattern specification" evidence=TAS] [GO:0004713 "protein tyrosine kinase activity" evidence=NAS] [GO:0005887 "integral component of plasma membrane" evidence=NAS] [GO:0008314 "gurken signaling pathway" evidence=NAS] [GO:0009950 "dorsal/ventral axis specification" evidence=NAS] [GO:0008313 "gurken-activated receptor activity" evidence=NAS] [GO:0007424 "open tracheal system development" evidence=TAS] [GO:0046845 "branched duct epithelial cell fate determination, open tracheal system" evidence=TAS] [GO:0035309 "wing and notum subfield formation" evidence=IMP] [GO:0007444 "imaginal disc development" evidence=NAS;IMP;TAS] [GO:0035310 "notum cell fate specification" evidence=IMP] [GO:0007477 "notum development" evidence=IMP] [GO:0007476 "imaginal disc-derived wing morphogenesis" evidence=NAS;IMP] [GO:0006468 "protein phosphorylation" evidence=IEA;NAS] [GO:0007298 "border follicle cell migration" evidence=IGI;IMP;TAS] [GO:0016330 "second mitotic wave involved in compound eye morphogenesis" evidence=IMP;TAS] [GO:0045165 "cell fate commitment" evidence=NAS] [GO:0000578 "embryonic axis specification" evidence=NAS] [GO:0007447 "imaginal disc pattern formation" evidence=NAS] [GO:0048477 "oogenesis" evidence=NAS] [GO:0030381 "chorion-containing eggshell pattern formation" evidence=IGI;TAS] [GO:0001751 "compound eye photoreceptor cell differentiation" evidence=IMP;TAS] [GO:0043066 "negative regulation of apoptotic process" evidence=IMP;NAS] [GO:0045468 "regulation of R8 cell spacing in compound eye" evidence=NAS;TAS] [GO:0007469 "antennal development" evidence=NAS] [GO:0007479 "leg disc proximal/distal pattern formation" evidence=IMP;TAS] [GO:0042676 "compound eye cone cell fate commitment" evidence=TAS] [GO:0030031 "cell projection assembly" evidence=IMP] [GO:0046673 "negative regulation of compound eye retinal cell programmed cell death" evidence=IMP;TAS] [GO:0007473 "wing disc proximal/distal pattern formation" evidence=TAS] [GO:0009953 "dorsal/ventral pattern formation" evidence=TAS] [GO:0007369 "gastrulation" evidence=TAS] [GO:0042694 "muscle cell fate specification" evidence=TAS] [GO:0048139 "female germ-line cyst encapsulation" evidence=TAS] [GO:0007350 "blastoderm segmentation" evidence=TAS] [GO:0016203 "muscle attachment" evidence=TAS] [GO:0007421 "stomatogastric nervous system development" evidence=TAS] [GO:0001742 "oenocyte differentiation" evidence=TAS] [GO:0048140 "male germ-line cyst encapsulation" evidence=TAS] [GO:0007474 "imaginal disc-derived wing vein specification" evidence=TAS] [GO:0009880 "embryonic pattern specification" evidence=IGI;TAS] [GO:0007420 "brain development" evidence=TAS] [GO:0004888 "transmembrane signaling receptor activity" evidence=TAS] [GO:0035202 "tracheal pit formation in open tracheal system" evidence=TAS] [GO:0045466 "R7 cell differentiation" evidence=TAS] [GO:0007472 "wing disc morphogenesis" evidence=IMP] [GO:0007422 "peripheral nervous system development" evidence=IMP] [GO:0007346 "regulation of mitotic cell cycle" evidence=TAS] [GO:0007458 "progression of morphogenetic furrow involved in compound eye morphogenesis" evidence=TAS] [GO:0001745 "compound eye morphogenesis" evidence=TAS] [GO:0000086 "G2/M transition of mitotic cell cycle" evidence=TAS] [GO:0001654 "eye development" evidence=IMP] [GO:0016318 "ommatidial rotation" evidence=IMP] [GO:0005524 "ATP binding" evidence=IEA] [GO:0019904 "protein domain specific binding" evidence=IEA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA] [GO:0045610 "regulation of hemocyte differentiation" evidence=IMP] [GO:0035225 "determination of genital disc primordium" evidence=IMP] [GO:2000134 "negative regulation of G1/S transition of mitotic cell cycle" evidence=IMP] [GO:0005515 "protein binding" evidence=IPI] [GO:0035277 "spiracle morphogenesis, open tracheal system" evidence=IMP] [GO:0007367 "segment polarity determination" evidence=IMP] [GO:0030718 "germ-line stem cell maintenance" evidence=IGI] [GO:0007455 "eye-antennal disc morphogenesis" evidence=IMP] [GO:0016337 "cell-cell adhesion" evidence=IMP] [GO:0035160 "maintenance of epithelial integrity, open tracheal system" evidence=IMP] [GO:0046843 "dorsal appendage formation" evidence=IMP] [GO:0007309 "oocyte axis specification" evidence=IMP] [GO:0035088 "establishment or maintenance of apical/basal cell polarity" evidence=IMP] [GO:0007482 "haltere development" evidence=IMP] [GO:0022008 "neurogenesis" evidence=IGI] [GO:0008284 "positive regulation of cell proliferation" evidence=IMP] [GO:0048149 "behavioral response to ethanol" evidence=IMP] [GO:0048865 "stem cell fate commitment" evidence=IMP] [GO:0003015 "heart process" evidence=IMP] [GO:0048546 "digestive tract morphogenesis" evidence=IMP] [GO:0008406 "gonad development" evidence=IMP] [GO:0090303 "positive regulation of wound healing" evidence=IMP] [GO:0008355 "olfactory learning" evidence=IMP] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS50011 SMART:SM00219 EMBL:AE013599 GO:GO:0016021 GO:GO:0005886 GO:GO:0005524 GO:GO:0000086 GO:GO:0043066 GO:GO:0008355 GO:GO:0007420 GO:GO:0042694 GO:GO:0007391 GO:GO:0003015 eggNOG:COG0515 GO:GO:0008284 GO:GO:0008586 GO:GO:0007474 BRENDA:2.7.10.1 SUPFAM:SSF56112 GO:GO:0061331 GO:GO:0007422 GO:GO:0035225 GO:GO:0007431 GO:GO:0035277 GO:GO:0007298 GO:GO:0016203 GO:GO:0048149 GO:GO:0016337 GO:GO:0090303 GO:GO:0007367 GO:GO:0008406 GO:GO:2000134 GO:GO:0030718 GO:GO:0007479 GO:GO:0035310 GO:GO:0007369 GO:GO:0046843 GO:GO:0030031 GO:GO:0001752 GO:GO:0007469 GO:GO:0016330 GO:GO:0007455 GO:GO:2001234 GO:GO:0007314 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0007458 GO:GO:0035160 GO:GO:0016318 GO:GO:0035088 GO:GO:0007310 GO:GO:0045610 GO:GO:0046845 GO:GO:0007473 GO:GO:0042676 GO:GO:0045468 Gene3D:3.80.20.20 GO:GO:0007390 CTD:1956 KO:K04361 EMBL:AF052754 EMBL:AF052753 EMBL:AF052752 EMBL:K03054 EMBL:K03417 EMBL:K03416 EMBL:AF109077 EMBL:AF109078 EMBL:AF109082 EMBL:AF109084 EMBL:AF109079 EMBL:AF109081 EMBL:AF109083 EMBL:AF109080 EMBL:X02293 EMBL:AJ002912 EMBL:X78920 EMBL:X78918 EMBL:X78919 PIR:A00640 RefSeq:NP_476759.1 UniGene:Dm.20748 PDB:3I2T PDB:3LTF PDB:3LTG PDBsum:3I2T PDBsum:3LTF PDBsum:3LTG ProteinModelPortal:P04412 SMR:P04412 BioGrid:63083 DIP:DIP-17316N IntAct:P04412 MINT:MINT-806082 PaxDb:P04412 GeneID:37455 KEGG:dme:Dmel_CG10079 FlyBase:FBgn0003731 InParanoid:P04412 OrthoDB:EOG7SV0TH SignaLink:P04412 ChiTaRS:EGFR EvolutionaryTrace:P04412 GenomeRNAi:37455 NextBio:803734 Bgee:P04412 GO:GO:0005006 GO:GO:0030381 GO:GO:0048139 GO:GO:0007482 GO:GO:0048140 GO:GO:0008071 GO:GO:0046673 GO:GO:0007477 GO:GO:0001742 GO:GO:0045466 GO:GO:0048865 GO:GO:0007421 GO:GO:0035202 Uniprot:P04412) HSP 1 Score: 743.806 bits (1919), Expect = 0.000e+0 Identity = 354/595 (59.50%), Postives = 424/595 (71.26%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTE-YFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLAG---------KAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRGCYG----MGPDKCLAC 659 GKICIGTK R+SVP+N+EHHYRNLRDRYTNCTYVDGNL+LTWL +ENLDLSFL +IREVTGY+LISHVDV+K+V P LQIIRGRTLF LSV ++K++L VT SKM+ LE+P LRD+L G VG NNYNLCH++TI+W EI++ Y Y Y+F PER+C CHESC GCWGEGP NCQKFSK+ CSPQC GRC+G PRECCHLFCAGGCTGP Q DC+AC+NFFD+ V K ECPPM++YNP Y E NPEGKYAYGATCVKECP HLL+DNGACVR CP K GECVPC+GPCPKTC V+HAGNIDSF+NCTVI+G+I ILD TF+GFQ+ Y NYT G RY +DP++ EVF+T+KE+TGY+NI+G HP F+NL+ FRNLE I GR L E F+AL IVK++L SL +++L++I SG+V I N+DLCY I W I K P + N C + +C QC+ +GCWG G + CL+CK F G G C+ CH C+ CNG G D CQECVH Q CV EC + Y D C+ C C GC G +G C C Sbjct: 99 GKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVTYSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAY-YNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGECVPCNGPCPKTCPGVTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYISNAYKFDNRTCKICHPECRTCNGAGA--DHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTC 690 HSP 2 Score: 98.2117 bits (243), Expect = 2.317e-19 Identity = 43/95 (45.26%), Postives = 60/95 (63.16%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYLTGE 669 Q QG L+PLAG+A+CR CH LC+ C YG+H+ VC +C H+ + +QC EC D+Y D + C EC GC G G D C +C+N+K++ E Sbjct: 723 QEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANE 817
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:EGFR "Epidermal growth factor receptor" species:9031 "Gallus gallus" [GO:0000139 "Golgi membrane" evidence=IEA] [GO:0004713 "protein tyrosine kinase activity" evidence=ISS] [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005634 "nucleus" evidence=ISS] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=ISS] [GO:0007611 "learning or memory" evidence=ISS] [GO:0010008 "endosome membrane" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0018108 "peptidyl-tyrosine phosphorylation" evidence=ISS] [GO:0031965 "nuclear membrane" evidence=IEA] [GO:0071364 "cellular response to epidermal growth factor stimulus" evidence=ISS] InterPro:IPR000494 InterPro:IPR006211 Pfam:PF00757 Pfam:PF01030 GO:GO:0016021 GO:GO:0005886 GO:GO:0005524 GO:GO:0005634 GO:GO:0007173 GO:GO:0000139 GO:GO:0005789 eggNOG:COG0515 GO:GO:0004714 GO:GO:0031965 GO:GO:0010008 GO:GO:0007611 GO:GO:0004713 GO:GO:0071364 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 Gene3D:3.80.20.20 EMBL:M20386 RefSeq:NP_990828.2 UniGene:Gga.35024 ProteinModelPortal:P13387 SMR:P13387 STRING:9031.ENSGALP00000020165 PaxDb:P13387 GeneID:396494 KEGG:gga:396494 CTD:1956 HOGENOM:HOG000230982 HOVERGEN:HBG000490 KO:K04361 NextBio:20816533 ArrayExpress:P13387 Uniprot:P13387) HSP 1 Score: 417.927 bits (1073), Expect = 4.149e-131 Identity = 251/629 (39.90%), Postives = 344/629 (54.69%), Query Frame = 0 Query: 80 KICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHY--------LEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESC-QSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECP-KHLLKDNGACVRICPPKKKTV--NG--ECVPCDGPCPKTCHFNEV--------MHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCKKCNGYGFHD-------DVCQECVHFSQDQQCVPECDG-----------DYYKDSTKCKPCSEEC-RGCYGMGPDKC 656 K+C GT +++ + E H+ +L+ Y NC V NLE+T+++ N DL+FL+ I+EV GYVLI+ V I L +LQIIRG L+ D+ F+L V LS H L M L +IL G V I NN LC++ T+ W +II R K + V +F C CH +C + CWG G NCQ +K+ C+ QC GRC G++P +CCH CA GCTGP++SDCLACR F DD K CPP+ YNP Y+ + NPEGKY++GATCV+ECP +++ D+G+CVR C V NG +C CDG C K C+ + ++A NIDSF+NCT I G ++IL F G F P +DPKKL+VF T+KE++G++ IQ N +L AF NLE+I GRT +L +V + SLGL+SL++I G ++I++NK+LCYA +NW+ + + S T + N+N +C H+CDP CS GCWGPG C SC+ F QG+ + C PCHS C N ++ D C +C HF CV C Y + C+ C C RGC G G + C Sbjct: 35 KVCQGTNNKLTQLGHVEDHFTSLQRMYNNCEVVLSNLEITYVE-HNRDLTFLKTIQEVAGYVLIALNMVDVIPLENLQIIRGNVLY-----DNSFALAV-LSNYHMNKTQGLRELPMKRLSEILNGGVKISNNPKLCNMDTVLWNDIIDTSR-KPLTVLDFASNLSSCPKCHPNCTEDHCWGAGEQNCQTLTKVICAQQC-SGRCRGKVPSDCCHNQCAAGCTGPRESDCLACRKFRDDATCKDTCPPLVLYNPTTYQMDVNPEGKYSFGATCVRECPHNYVVTDHGSCVRSCNTDTYEVEENGVRKCKKCDGLCSKVCNGIGIGELKGILSINATNIDSFKNCTKINGDVSILPVAFLG-------DAFTKTLP-LDPKKLDVFRTVKEISGFLLIQAWPDNATDLYAFENLEIIRGRTKQHGQYSLAVVNLKIQSLGLRSLKEISDGDIAIMKNKNLCYADTMNWRSLFATQSQKTKIIQNRNKNDCTADRHVCDPLCSDVGCWGPGPFHCFSCRFFSRQKECVKQCNILQGEPREFERDSKCLPCHSECLVQNSTAYNTTCSGPGPDHCMKCAHFIDGPHCVKACPAGVLGENDTLVWKYADANAVCQLCHPNCTRGCKGPGLEGC 646
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:ERBB3 "cDNA FLJ59207, highly similar to Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1)" species:9606 "Homo sapiens" [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA] [GO:0016020 "membrane" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR011009 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PRINTS:PR00109 PROSITE:PS50011 GO:GO:0005524 GO:GO:0016020 GO:GO:0004714 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0007169 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 EMBL:AC034102 Gene3D:3.80.20.20 HOVERGEN:HBG000490 UniGene:Hs.118681 UniGene:Hs.622058 HGNC:HGNC:3431 ChiTaRS:ERBB3 EMBL:AK294719 ProteinModelPortal:B4DGQ7 SMR:B4DGQ7 Ensembl:ENST00000551085 NextBio:35471814 ArrayExpress:B4DGQ7 Uniprot:B4DGQ7) HSP 1 Score: 420.624 bits (1080), Expect = 1.124e-129 Identity = 240/625 (38.40%), Postives = 333/625 (53.28%), Query Frame = 0 Query: 81 ICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCK------KCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 +C GT +SV + E+ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L + L +IL G V I N LCH+ TI+W +I+ + V N R C PCHE C+ CWG G +CQ +K C+PQC+ G CFG P +CCH CAGGC+GP+ +DC ACR+F D G CP YN + ++ E NP KY YG CV CP + + D +CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + NG ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G + I N+ LCY +NW K+++ P+ L +++N+ ++C+ + +CDP CS+ GCWGPG CLSC+ + G+ A +A C CH C+ CNG G D C +C HF CV C G YK +C+PC E C +GC G CL Sbjct: 28 VCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDN----GRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCN-GHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLNG--------DPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSG--SDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQGCKGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:EGFR "Epidermal growth factor receptor" species:9031 "Gallus gallus" [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016245 InterPro:IPR017441 InterPro:IPR020635 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000619 PRINTS:PR00109 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS50011 SMART:SM00219 GO:GO:0016021 GO:GO:0005524 GO:GO:0035556 GO:GO:0004714 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0007169 GO:GO:0023014 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 Gene3D:3.80.20.20 RefSeq:NP_990828.2 UniGene:Gga.35024 GeneID:396494 KEGG:gga:396494 CTD:1956 KO:K04361 GO:GO:0004716 GeneTree:ENSGT00600000084253 OrthoDB:EOG7V49XM EMBL:AADN03002453 EMBL:AADN03002704 EMBL:AADN03002891 Ensembl:ENSGALT00000037413 Uniprot:E1C0S3) HSP 1 Score: 424.476 bits (1090), Expect = 2.247e-128 Identity = 252/629 (40.06%), Postives = 345/629 (54.85%), Query Frame = 0 Query: 80 KICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHY--------LEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESC-QSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECP-KHLLKDNGACVRICPPKKKTV--NG--ECVPCDGPCPKTCH---FNEV-----MHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCKKCNGYGFHD-------DVCQECVHFSQDQQCVPECDG-----------DYYKDSTKCKPCSEEC-RGCYGMGPDKC 656 K+C GT +++ + E H+ +L+ Y NC V NLE+T+++ N DL+FL+ I+EV GYVLI+ V I L +LQIIRG L+ D+ F+L V LS H L M L +IL G V I NN LC++ T+ W +II R K + V +F C CH +C + CWG G NCQ +K+ C+ QC GRC G++P +CCH CA GCTGP++SDCLACR F DD K CPP+ YNP Y+ + NPEGKY++GATCV+ECP +++ D+G+CVR C V NG +C CDG C K C+ E+ ++A NIDSF+NCT I G ++IL F G F P +DPKKL+VF T+KE++G++ IQ N +L AF NLE+I GRT +L +V + SLGL+SL++I G ++I++NK+LCYA +NW+ + + S T + N+N +C H+CDP CS GCWGPG C SC+ F QG+ + C PCHS C N ++ D C +C HF CV C Y + C+ C C RGC G G + C Sbjct: 38 KVCQGTNNKLTQLGHVEDHFTSLQRMYNNCEVVLSNLEITYVE-HNRDLTFLKTIQEVAGYVLIALNMVDVIPLENLQIIRGNVLY-----DNSFALAV-LSNYHMNKTQGLRELPMKRLSEILNGGVKISNNPKLCNMDTVLWNDIIDTSR-KPLTVLDFASNLSSCPKCHPNCTEDHCWGAGEQNCQTLTKVICAQQC-SGRCRGKVPSDCCHNQCAAGCTGPRESDCLACRKFRDDATCKDTCPPLVLYNPTTYQMDVNPEGKYSFGATCVRECPHNYVVTDHGSCVRSCNTDTYEVEENGVRKCKKCDGLCSKVCNGIGIGELKGILSINATNIDSFKNCTKINGDVSILPVAFLG-------DAFTKTLP-LDPKKLDVFRTVKEISGFLLIQAWPDNATDLYAFENLEIIRGRTKQHGQYSLAVVNLKIQSLGLRSLKEISDGDIAIMKNKNLCYADTMNWRSLFATQSQKTKIIQNRNKNDCTADRHVCDPLCSDVGCWGPGPFHCFSCRFFSRQKECVKQCNILQGEPREFERDSKCLPCHSECLVQNSTAYNTTCSGPGPDHCMKCAHFIDGPHCVKACPAGVLGENDTLVWKYADANAVCQLCHPNCTRGCKGPGLEGC 649
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:ERBB3 "ERBB3 protein" species:9913 "Bos taurus" [GO:0003197 "endocardial cushion development" evidence=IEA] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA] [GO:0004888 "transmembrane signaling receptor activity" evidence=IDA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005615 "extracellular space" evidence=IEA] [GO:0007162 "negative regulation of cell adhesion" evidence=IEA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IDA] [GO:0009968 "negative regulation of signal transduction" evidence=IEA] [GO:0014037 "Schwann cell differentiation" evidence=IEA] [GO:0014065 "phosphatidylinositol 3-kinase signaling" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016323 "basolateral plasma membrane" evidence=IEA] [GO:0016324 "apical plasma membrane" evidence=IEA] [GO:0016328 "lateral plasma membrane" evidence=IEA] [GO:0019838 "growth factor binding" evidence=IPI] [GO:0021545 "cranial nerve development" evidence=IEA] [GO:0030296 "protein tyrosine kinase activator activity" evidence=IEA] [GO:0042127 "regulation of cell proliferation" evidence=IEA] [GO:0043235 "receptor complex" evidence=IDA] [GO:0043524 "negative regulation of neuron apoptotic process" evidence=IEA] [GO:0046982 "protein heterodimerization activity" evidence=IEA] [GO:0051048 "negative regulation of secretion" evidence=IEA] [GO:0051402 "neuron apoptotic process" evidence=IEA] [GO:0097192 "extrinsic apoptotic signaling pathway in absence of ligand" evidence=IEA] [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IDA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR011009 InterPro:IPR016245 InterPro:IPR020635 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000619 PRINTS:PR00109 PROSITE:PS50011 SMART:SM00219 GO:GO:0016021 GO:GO:0005524 GO:GO:0005615 GO:GO:0016324 GO:GO:0014065 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0051402 GO:GO:0043235 GO:GO:0016323 GO:GO:0043524 GO:GO:0042127 GO:GO:0030296 GO:GO:0007169 GO:GO:0004888 GO:GO:0023014 GO:GO:0007162 GO:GO:0016328 GO:GO:0009968 GO:GO:0097192 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0003197 GO:GO:0021545 GO:GO:0014037 Gene3D:3.80.20.20 HOGENOM:HOG000230982 HOVERGEN:HBG000490 TreeFam:TF106002 GO:GO:0004716 GeneTree:ENSGT00600000084253 GO:GO:0051048 OrthoDB:EOG7V49XM CTD:2065 KO:K05084 OMA:CYHHSLN EMBL:DAAA02013534 EMBL:BC150128 RefSeq:NP_001096575.1 UniGene:Bt.64779 SMR:A6QR62 Ensembl:ENSBTAT00000013790 GeneID:785655 KEGG:bta:785655 InParanoid:A6QR62 NextBio:20927417 Uniprot:A6QR62) HSP 1 Score: 425.246 bits (1092), Expect = 5.957e-128 Identity = 240/625 (38.40%), Postives = 334/625 (53.44%), Query Frame = 0 Query: 81 ICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCK------KCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 +C GT +SV + E+ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L + L +IL G V I N LCH+ TI+W +I+ + V N + C PCHE+C+ CWG GP +CQ +K C+PQC+ G CFG P +CCH CAGGC+GP+ +DC ACR F D G +CP YN + ++ E NP KY YG CV CP + + D +CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + NG ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G + I N+ LCY +NW ++++ PS L +++N+ ++C+ + +CDP CS GCWGPG CLSC+ + G+ A +A C CH C+ CNG G D C +C HF CV C G YK +C+PC E C +GC G CL Sbjct: 28 VCPGTLNGLSVTGDAENQYQTLHKLYEKCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNEKLCHMDTIDWRDIVRDRDAEIVVKNN----GKTCPPCHEACKGRCWGPGPEDCQTLTKTICAPQCN-GHCFGPNPNQCCHDECAGGCSGPQNTDCFACRLFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKICEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLNG--------DPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTRLLRGPSEERLDIKHNRPRRDCVAEGKVCDPLCSG-GCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHQECQPMEGTVTCNGSG--SDACAQCAHFRDGPHCVSSCPFGVLGAKGPIYKYPDAQNECRPCHENCTQGCKGPELQDCLG 630
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:ERBB3 "Receptor tyrosine-protein kinase erbB-3" species:9606 "Homo sapiens" [GO:0003197 "endocardial cushion development" evidence=IEA] [GO:0004888 "transmembrane signaling receptor activity" evidence=ISS] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005615 "extracellular space" evidence=IDA] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0005887 "integral component of plasma membrane" evidence=TAS] [GO:0007162 "negative regulation of cell adhesion" evidence=IDA] [GO:0007165 "signal transduction" evidence=IDA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=ISS] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=TAS] [GO:0007422 "peripheral nervous system development" evidence=ISS] [GO:0007507 "heart development" evidence=ISS] [GO:0008543 "fibroblast growth factor receptor signaling pathway" evidence=TAS] [GO:0009968 "negative regulation of signal transduction" evidence=IDA] [GO:0014037 "Schwann cell differentiation" evidence=ISS] [GO:0014065 "phosphatidylinositol 3-kinase signaling" evidence=IDA] [GO:0014068 "positive regulation of phosphatidylinositol 3-kinase signaling" evidence=TAS] [GO:0016323 "basolateral plasma membrane" evidence=IDA] [GO:0016324 "apical plasma membrane" evidence=IEA] [GO:0016328 "lateral plasma membrane" evidence=IEA] [GO:0019838 "growth factor binding" evidence=ISS;IPI] [GO:0021545 "cranial nerve development" evidence=ISS] [GO:0030296 "protein tyrosine kinase activator activity" evidence=IDA] [GO:0038095 "Fc-epsilon receptor signaling pathway" evidence=TAS] [GO:0042060 "wound healing" evidence=NAS] [GO:0042127 "regulation of cell proliferation" evidence=IDA] [GO:0042803 "protein homodimerization activity" evidence=NAS] [GO:0043235 "receptor complex" evidence=ISS;IDA] [GO:0043524 "negative regulation of neuron apoptotic process" evidence=ISS] [GO:0045087 "innate immune response" evidence=TAS] [GO:0046982 "protein heterodimerization activity" evidence=IDA;IPI] [GO:0048011 "neurotrophin TRK receptor signaling pathway" evidence=TAS] [GO:0048015 "phosphatidylinositol-mediated signaling" evidence=TAS] [GO:0051048 "negative regulation of secretion" evidence=IDA] [GO:0051402 "neuron apoptotic process" evidence=IMP] [GO:0061098 "positive regulation of protein tyrosine kinase activity" evidence=IMP] [GO:0097192 "extrinsic apoptotic signaling pathway in absence of ligand" evidence=IMP] [GO:0004713 "protein tyrosine kinase activity" evidence=IDA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR011009 InterPro:IPR016245 InterPro:IPR020635 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000619 PRINTS:PR00109 PROSITE:PS50011 SMART:SM00219 GO:GO:0005524 Reactome:REACT_111102 Reactome:REACT_116125 Reactome:REACT_6900 GO:GO:0007173 GO:GO:0038095 GO:GO:0008543 GO:GO:0045087 GO:GO:0048011 GO:GO:0005615 GO:GO:0042803 GO:GO:0007507 GO:GO:0005887 GO:GO:0016324 eggNOG:COG0515 GO:GO:0014065 BRENDA:2.7.10.1 SUPFAM:SSF56112 GO:GO:0051402 GO:GO:0043235 GO:GO:0016323 GO:GO:0043524 GO:GO:0014068 GO:GO:0004672 GO:GO:0042127 GO:GO:0030296 GO:GO:0004888 GO:GO:0019838 GO:GO:0007162 GO:GO:0046982 GO:GO:0042060 GO:GO:0016328 GO:GO:0009968 GO:GO:0097192 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0003197 EMBL:AC034102 GO:GO:0021545 GO:GO:0014037 Gene3D:3.80.20.20 HOGENOM:HOG000230982 HOVERGEN:HBG000490 ChEMBL:CHEMBL2363049 TreeFam:TF106002 GO:GO:0051048 OrthoDB:EOG7V49XM EMBL:M29366 EMBL:M34309 EMBL:S61953 EMBL:BT007226 EMBL:AK291681 EMBL:AK295650 EMBL:AK300909 EMBL:BC002706 EMBL:BC082992 PIR:A36223 PIR:JH0803 RefSeq:NP_001005915.1 RefSeq:NP_001973.2 UniGene:Hs.118681 UniGene:Hs.622058 PDB:1M6B PDB:2L9U PDB:3KEX PDB:3LMG PDB:3P11 PDB:4LEO PDBsum:1M6B PDBsum:2L9U PDBsum:3KEX PDBsum:3LMG PDBsum:3P11 PDBsum:4LEO ProteinModelPortal:P21860 SMR:P21860 BioGrid:108377 DIP:DIP-36441N IntAct:P21860 MINT:MINT-158484 STRING:9606.ENSP00000267101 BindingDB:P21860 GuidetoPHARMACOLOGY:1798 PhosphoSite:P21860 DMDM:119534 PaxDb:P21860 PRIDE:P21860 DNASU:2065 Ensembl:ENST00000267101 Ensembl:ENST00000411731 Ensembl:ENST00000415288 Ensembl:ENST00000450146 Ensembl:ENST00000551242 GeneID:2065 KEGG:hsa:2065 UCSC:uc001sjg.3 UCSC:uc001sjh.3 CTD:2065 GeneCards:GC12P056473 HGNC:HGNC:3431 HPA:CAB025331 HPA:HPA045396 MIM:190151 MIM:607598 neXtProt:NX_P21860 Orphanet:137776 PharmGKB:PA27846 InParanoid:P21860 KO:K05084 OMA:CYHHSLN PhylomeDB:P21860 SignaLink:P21860 ChiTaRS:ERBB3 EvolutionaryTrace:P21860 GeneWiki:ERBB3 GenomeRNAi:2065 NextBio:8391 PRO:PR:P21860 ArrayExpress:P21860 Bgee:P21860 CleanEx:HS_ERBB3 Genevestigator:P21860 Uniprot:P21860) HSP 1 Score: 424.861 bits (1091), Expect = 1.069e-127 Identity = 243/632 (38.45%), Postives = 336/632 (53.16%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCK------KCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 NSQ +C GT +SV + E+ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L + L +IL G V I N LCH+ TI+W +I+ + V N R C PCHE C+ CWG G +CQ +K C+PQC+ G CFG P +CCH CAGGC+GP+ +DC ACR+F D G CP YN + ++ E NP KY YG CV CP + + D +CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + NG ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G + I N+ LCY +NW K+++ P+ L +++N+ ++C+ + +CDP CS+ GCWGPG CLSC+ + G+ A +A C CH C+ CNG G D C +C HF CV C G YK +C+PC E C +GC G CL Sbjct: 24 NSQ---AVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDN----GRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCN-GHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLNG--------DPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSG--SDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQGCKGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:Erbb3 "Receptor tyrosine-protein kinase erbB-3" species:10116 "Rattus norvegicus" [GO:0003197 "endocardial cushion development" evidence=IEA] [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005615 "extracellular space" evidence=IEA] [GO:0007162 "negative regulation of cell adhesion" evidence=IEA] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA] [GO:0009968 "negative regulation of signal transduction" evidence=IEA] [GO:0014037 "Schwann cell differentiation" evidence=IEA] [GO:0014065 "phosphatidylinositol 3-kinase signaling" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016323 "basolateral plasma membrane" evidence=IEA] [GO:0016324 "apical plasma membrane" evidence=IEA] [GO:0016328 "lateral plasma membrane" evidence=IEA] [GO:0019838 "growth factor binding" evidence=IEA] [GO:0021545 "cranial nerve development" evidence=IEA] [GO:0030296 "protein tyrosine kinase activator activity" evidence=IEA] [GO:0042127 "regulation of cell proliferation" evidence=IEA] [GO:0043524 "negative regulation of neuron apoptotic process" evidence=IEA] [GO:0046982 "protein heterodimerization activity" evidence=IEA] [GO:0051048 "negative regulation of secretion" evidence=IEA] [GO:0051402 "neuron apoptotic process" evidence=IEA] [GO:0097192 "extrinsic apoptotic signaling pathway in absence of ligand" evidence=IEA] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016245 InterPro:IPR020635 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000619 PRINTS:PR00109 PROSITE:PS00109 PROSITE:PS50011 SMART:SM00219 RGD:69323 GO:GO:0016021 GO:GO:0005524 GO:GO:0005615 GO:GO:0016324 GO:GO:0014065 GO:GO:0004714 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0051402 GO:GO:0016323 GO:GO:0043524 GO:GO:0042127 GO:GO:0030296 GO:GO:0007169 GO:GO:0023014 GO:GO:0007162 GO:GO:0016328 GO:GO:0009968 GO:GO:0097192 EMBL:CH474104 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0003197 GO:GO:0021545 GO:GO:0014037 Gene3D:3.80.20.20 TreeFam:TF106002 GO:GO:0004716 GeneTree:ENSGT00600000084253 GO:GO:0051048 OrthoDB:EOG7V49XM OMA:CYHHSLN UniGene:Rn.10228 EMBL:AABR06047173 Ensembl:ENSRNOT00000006796 NextBio:35583763 PRO:PR:G3V6N1 Uniprot:G3V6N1) HSP 1 Score: 424.476 bits (1090), Expect = 1.227e-127 Identity = 247/632 (39.08%), Postives = 334/632 (52.85%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLC------KKCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 NSQ +C GT +SV + ++ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L+ L +IL G V I N LCH+ TI+W +I+ RG + V N +C PCHE C+ CWG GP +CQ +K C+PQC+ GRCFG P +CCH CAGGC+GP+ +DC ACR F D G CP YN + ++ E NP KY YG CV CP + + D CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + NG ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G V I N+ LCY +NW ++++ PS L ++ N+ EC+ + +CDP CS+ GCWGPG CLSC+ + QG+ +A C CH C CNG G D C C HF CV C G YK +C+PC E C +GC G CL Sbjct: 24 NSQ---AVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLKFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVR-VRGAEIVVKNNGA---NCPPCHEVCKGRCWGPGPDDCQILTKTICAPQCN-GRCFGPNPNQCCHDECAGGCSGPQDTDCFACRRFNDSGACVPRCPEPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTFCVRACPPDKMEVDKHGLKMCEPCGGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGLNG--------DPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPSEERLDIKYNRPLGECLAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNFLQGEPREFVHEAQCFSCHPECLPMEGTSTCNGSG--SDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCNGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:Erbb3 "v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)" species:10090 "Mus musculus" [GO:0000166 "nucleotide binding" evidence=IEA] [GO:0003197 "endocardial cushion development" evidence=IMP] [GO:0004672 "protein kinase activity" evidence=IEA] [GO:0004713 "protein tyrosine kinase activity" evidence=ISO] [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005615 "extracellular space" evidence=ISO] [GO:0005634 "nucleus" evidence=ISO] [GO:0006468 "protein phosphorylation" evidence=IEA] [GO:0007162 "negative regulation of cell adhesion" evidence=ISO] [GO:0007165 "signal transduction" evidence=ISO] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=ISO] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=ISO] [GO:0007422 "peripheral nervous system development" evidence=IMP] [GO:0009968 "negative regulation of signal transduction" evidence=ISO] [GO:0014037 "Schwann cell differentiation" evidence=IMP] [GO:0014065 "phosphatidylinositol 3-kinase signaling" evidence=ISO] [GO:0016020 "membrane" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016301 "kinase activity" evidence=IEA] [GO:0016310 "phosphorylation" evidence=IEA] [GO:0016323 "basolateral plasma membrane" evidence=ISO] [GO:0016324 "apical plasma membrane" evidence=IDA] [GO:0016328 "lateral plasma membrane" evidence=IDA] [GO:0016740 "transferase activity" evidence=IEA] [GO:0016772 "transferase activity, transferring phosphorus-containing groups" evidence=IEA] [GO:0019838 "growth factor binding" evidence=ISO] [GO:0021545 "cranial nerve development" evidence=IMP] [GO:0030296 "protein tyrosine kinase activator activity" evidence=ISO] [GO:0038131 "neuregulin receptor activity" evidence=ISO] [GO:0038132 "neuregulin binding" evidence=ISO] [GO:0042127 "regulation of cell proliferation" evidence=ISO] [GO:0043235 "receptor complex" evidence=ISO] [GO:0043524 "negative regulation of neuron apoptotic process" evidence=IMP] [GO:0045211 "postsynaptic membrane" evidence=ISO] [GO:0046326 "positive regulation of glucose import" evidence=ISO] [GO:0046982 "protein heterodimerization activity" evidence=ISO] [GO:0051048 "negative regulation of secretion" evidence=ISO] [GO:0051402 "neuron apoptotic process" evidence=ISO] [GO:0061098 "positive regulation of protein tyrosine kinase activity" evidence=ISO] [GO:0097192 "extrinsic apoptotic signaling pathway in absence of ligand" evidence=ISO] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016245 InterPro:IPR020635 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000619 PRINTS:PR00109 PROSITE:PS00109 PROSITE:PS50011 SMART:SM00219 MGI:MGI:95411 GO:GO:0016021 GO:GO:0005524 GO:GO:0005615 GO:GO:0016324 eggNOG:COG0515 GO:GO:0014065 GO:GO:0004714 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0051402 GO:GO:0043235 GO:GO:0016323 GO:GO:0043524 GO:GO:0042127 GO:GO:0030296 GO:GO:0007169 GO:GO:0023014 GO:GO:0007162 GO:GO:0016328 GO:GO:0009968 GO:GO:0097192 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0003197 GO:GO:0021545 GO:GO:0014037 Gene3D:3.80.20.20 HOGENOM:HOG000230982 HOVERGEN:HBG000490 TreeFam:TF106002 GO:GO:0004716 GeneTree:ENSGT00600000084253 GO:GO:0051048 OrthoDB:EOG7V49XM CTD:2065 KO:K05084 OMA:CYHHSLN ChiTaRS:ERBB3 EMBL:AY686636 EMBL:BC029028 EMBL:BC049279 EMBL:BC106091 EMBL:L47240 RefSeq:NP_034283.1 UniGene:Mm.373043 ProteinModelPortal:Q61526 SMR:Q61526 IntAct:Q61526 PhosphoSite:Q61526 PaxDb:Q61526 PRIDE:Q61526 Ensembl:ENSMUST00000082059 GeneID:13867 KEGG:mmu:13867 UCSC:uc007hnm.1 InParanoid:Q61526 NextBio:284768 PRO:PR:Q61526 Bgee:Q61526 Genevestigator:Q61526 Uniprot:Q61526) HSP 1 Score: 421.779 bits (1083), Expect = 1.323e-126 Identity = 244/632 (38.61%), Postives = 333/632 (52.69%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCK------KCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 NSQ +C GT +SV + ++ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L L +IL G V I N LCH+ TI+W +I+ P + V N +C PCHE C+ CWG GP +CQ +K C+PQC+ GRCFG P +CCH CAGGC+GP+ +DC ACR+F D G CP YN + ++ E NP KY YG CV CP + + D CVR CP K V+ C PC G CPK C + + + NID F NCT I G++ L + NG ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G V I N+ LCY +NW ++++ P+ L ++ N+ EC+ + +CDP CS+ GCWGPG CLSC+ + QG+ +A C CH C+ CNG G D C C HF CV C G YK +C+PC E C +GC G CL Sbjct: 24 NSQ---AVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVKNNGG----NCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCN-GRCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQTFCVRACPADKMEVDKNGLKMCEPCRGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGLNG--------DPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPAEERLDIKYNRPLGECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEPREFVHEAHCFSCHPECQPMEGTSTCNGSG--SDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCKGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:Erbb3 "Receptor tyrosine-protein kinase erbB-3" species:10116 "Rattus norvegicus" [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0018108 "peptidyl-tyrosine phosphorylation" evidence=TAS] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016245 InterPro:IPR020635 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000619 PRINTS:PR00109 PROSITE:PS00109 PROSITE:PS50011 SMART:SM00219 RGD:69323 GO:GO:0016021 GO:GO:0005524 GO:GO:0005634 GO:GO:0007173 GO:GO:0032869 GO:GO:0009611 GO:GO:0042493 GO:GO:0035556 eggNOG:COG0515 GO:GO:0045211 GO:GO:0007623 BRENDA:2.7.10.1 GO:GO:0004714 SUPFAM:SSF56112 GO:GO:0046326 GO:GO:0007409 GO:GO:0023014 GO:GO:0042476 GO:GO:0060056 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0043586 GO:GO:0007519 Gene3D:3.80.20.20 HOGENOM:HOG000230982 HOVERGEN:HBG000490 GO:GO:0004716 CTD:2065 KO:K05084 EMBL:U29339 EMBL:U52530 PIR:JC4387 RefSeq:NP_058914.2 UniGene:Rn.10228 ProteinModelPortal:Q62799 SMR:Q62799 BioGrid:248136 MINT:MINT-132305 STRING:10116.ENSRNOP00000006796 PhosphoSite:Q62799 PaxDb:Q62799 PRIDE:Q62799 GeneID:29496 KEGG:rno:29496 UCSC:RGD:69323 InParanoid:Q62799 NextBio:609384 PRO:PR:Q62799 Genevestigator:Q62799 GO:GO:0038132 GO:GO:0038131 Uniprot:Q62799) HSP 1 Score: 420.624 bits (1080), Expect = 3.352e-126 Identity = 245/632 (38.77%), Postives = 333/632 (52.69%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLC------KKCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 NSQ +C GT +SV + ++ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L+ L +IL G V I N LCH+ TI+W +I+ RG + V N +C PCHE C+ CWG GP +CQ +K C+PQC+ GRCFG P +CCH CAGGC+GP+ +DC ACR F D G CP YN + ++ E NP KY YG CV CP + + D CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + N ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G V I N+ LCY +NW ++++ PS L ++ ++ EC+ + +CDP CS+ GCWGPG CLSC+ + QG+ +A C CH C CNG G D C C HF CV C G YK +C+PC E C +GC G CL Sbjct: 24 NSQ---AVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLKFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVR-VRGAEIVVKNNGA---NCPPCHEVCKGRCWGPGPDDCQILTKTICAPQCN-GRCFGPNPNQCCHDECAGGCSGPQDTDCFACRRFNDSGACVPRCPEPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTFCVRACPPDKMEVDKHGLKMCEPCGGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGL--------NVDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPSEERLDIKYDRPLGECLAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNFLQGEPREFVHEAQCFSCHPECLPMEGTSTCNGSG--SDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCNGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. GO
Match: - (symbol:Erbb3 "v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3" species:10116 "Rattus norvegicus" [GO:0003197 "endocardial cushion development" evidence=IEA;ISO] [GO:0004714 "transmembrane receptor protein tyrosine kinase activity" evidence=IEA;TAS] [GO:0004716 "receptor signaling protein tyrosine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005615 "extracellular space" evidence=IEA;ISO] [GO:0005634 "nucleus" evidence=IDA] [GO:0007162 "negative regulation of cell adhesion" evidence=IEA;ISO] [GO:0007165 "signal transduction" evidence=ISO] [GO:0007169 "transmembrane receptor protein tyrosine kinase signaling pathway" evidence=IEA;TAS] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=IMP] [GO:0007409 "axonogenesis" evidence=IEP] [GO:0007422 "peripheral nervous system development" evidence=ISO] [GO:0007519 "skeletal muscle tissue development" evidence=IEP] [GO:0007623 "circadian rhythm" evidence=IEP] [GO:0009611 "response to wounding" evidence=IEP] [GO:0009968 "negative regulation of signal transduction" evidence=IEA;ISO] [GO:0014037 "Schwann cell differentiation" evidence=IEA;ISO] [GO:0014065 "phosphatidylinositol 3-kinase signaling" evidence=IEA;ISO] [GO:0016021 "integral component of membrane" evidence=IEA;TAS] [GO:0016323 "basolateral plasma membrane" evidence=IEA;ISO] [GO:0016324 "apical plasma membrane" evidence=IEA;ISO] [GO:0016328 "lateral plasma membrane" evidence=IEA;ISO] [GO:0018108 "peptidyl-tyrosine phosphorylation" evidence=TAS] [GO:0019838 "growth factor binding" evidence=IEA;ISO] [GO:0021545 "cranial nerve development" evidence=IEA;ISO] [GO:0030296 "protein tyrosine kinase activator activity" evidence=IEA;ISO] [GO:0032869 "cellular response to insulin stimulus" evidence=IEP] [GO:0038131 "neuregulin receptor activity" evidence=IMP] [GO:0038132 "neuregulin binding" evidence=IMP] [GO:0042127 "regulation of cell proliferation" evidence=IEA;ISO] [GO:0042476 "odontogenesis" evidence=IEP] [GO:0042493 "response to drug" evidence=IEP] [GO:0043235 "receptor complex" evidence=ISO] [GO:0043524 "negative regulation of neuron apoptotic process" evidence=IEA;ISO] [GO:0043586 "tongue development" evidence=IEP] [GO:0045211 "postsynaptic membrane" evidence=IDA] [GO:0046326 "positive regulation of glucose import" evidence=IMP] [GO:0046982 "protein heterodimerization activity" evidence=IEA;ISO] [GO:0051048 "negative regulation of secretion" evidence=IEA;ISO] [GO:0051402 "neuron apoptotic process" evidence=IEA;ISO] [GO:0060056 "mammary gland involution" evidence=IEP] [GO:0061098 "positive regulation of protein tyrosine kinase activity" evidence=ISO] [GO:0097192 "extrinsic apoptotic signaling pathway in absence of ligand" evidence=IEA;ISO] [GO:0004713 "protein tyrosine kinase activity" evidence=ISO] InterPro:IPR000494 InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR006211 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR016245 InterPro:IPR020635 Pfam:PF00757 Pfam:PF01030 Pfam:PF07714 PIRSF:PIRSF000619 PRINTS:PR00109 PROSITE:PS00109 PROSITE:PS50011 SMART:SM00219 RGD:69323 GO:GO:0016021 GO:GO:0005524 GO:GO:0005634 GO:GO:0007173 GO:GO:0032869 GO:GO:0009611 GO:GO:0042493 GO:GO:0035556 eggNOG:COG0515 GO:GO:0045211 GO:GO:0007623 BRENDA:2.7.10.1 GO:GO:0004714 SUPFAM:SSF56112 GO:GO:0046326 GO:GO:0007409 GO:GO:0023014 GO:GO:0042476 GO:GO:0060056 InterPro:IPR006212 InterPro:IPR009030 SMART:SM00261 SUPFAM:SSF57184 GO:GO:0043586 GO:GO:0007519 Gene3D:3.80.20.20 HOGENOM:HOG000230982 HOVERGEN:HBG000490 GO:GO:0004716 CTD:2065 KO:K05084 EMBL:U29339 EMBL:U52530 PIR:JC4387 RefSeq:NP_058914.2 UniGene:Rn.10228 ProteinModelPortal:Q62799 SMR:Q62799 BioGrid:248136 MINT:MINT-132305 STRING:10116.ENSRNOP00000006796 PhosphoSite:Q62799 PaxDb:Q62799 PRIDE:Q62799 GeneID:29496 KEGG:rno:29496 UCSC:RGD:69323 InParanoid:Q62799 NextBio:609384 PRO:PR:Q62799 Genevestigator:Q62799 GO:GO:0038132 GO:GO:0038131 Uniprot:Q62799) HSP 1 Score: 420.624 bits (1080), Expect = 3.352e-126 Identity = 245/632 (38.77%), Postives = 333/632 (52.69%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLC------KKCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 NSQ +C GT +SV + ++ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L+ L +IL G V I N LCH+ TI+W +I+ RG + V N +C PCHE C+ CWG GP +CQ +K C+PQC+ GRCFG P +CCH CAGGC+GP+ +DC ACR F D G CP YN + ++ E NP KY YG CV CP + + D CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + N ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G V I N+ LCY +NW ++++ PS L ++ ++ EC+ + +CDP CS+ GCWGPG CLSC+ + QG+ +A C CH C CNG G D C C HF CV C G YK +C+PC E C +GC G CL Sbjct: 24 NSQ---AVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLKFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVR-VRGAEIVVKNNGA---NCPPCHEVCKGRCWGPGPDDCQILTKTICAPQCN-GRCFGPNPNQCCHDECAGGCSGPQDTDCFACRRFNDSGACVPRCPEPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTFCVRACPPDKMEVDKHGLKMCEPCGGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGL--------NVDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPSEERLDIKYDRPLGECLAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNFLQGEPREFVHEAQCFSCHPECLPMEGTSTCNGSG--SDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCNGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816144|gb|GAXK01138424.1| (TSA: Calanus finmarchicus comp102350_c1_seq4 transcribed RNA sequence) HSP 1 Score: 723.005 bits (1865), Expect = 0.000e+0 Identity = 337/435 (77.47%), Postives = 382/435 (87.82%), Query Frame = 0 Query: 35 PQFTKMRIXXXXXCIVLWKNPSPVEASSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRN 469 P K+++ + I+L + AS ++ R ++ HGKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFL+HIREVTGYVLISHVDVR+I+LPSLQI+RGRTLFKL+V+DD+F+L+VTLSKMH LEMPALRDIL GSVGILNNYNLCHIKTI+W+EIITG +YVYVYNF EPERDCTPCHESC++GCWGEGP+NCQKFSKINC+ QCH GRCFG PRECCHLFCAGGCTGPKQSDCLAC+NF+DDGV K ECPPMQ YNPIKY+WE++P+GKYAYGATCVKECP+HLLKDNGACVR CPPKKK V+GECVPCDGPCPK CHF + +HAGNID+F+NCTV+EGS+TILDSTFNGFQ+ Y+N+TFG RYPAMDP KLEVF TLKEVTGYINIQ HHP F NL+AF N Sbjct: 23 PSTFKIKMNSSHIFILLVATFASFSASQ--ALERPKERDSNVRHGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLEHIREVTGYVLISHVDVRRIILPSLQIVRGRTLFKLTVQDDEFALIVTLSKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEIITGQNARYVYVYNFKEPERDCTPCHESCENGCWGEGPNNCQKFSKINCAAQCHSGRCFGPKPRECCHLFCAGGCTGPKQSDCLACKNFYDDGVCKQECPPMQIYNPIKYKWERDPQGKYAYGATCVKECPEHLLKDNGACVRACPPKKKAVDGECVPCDGPCPKICHFTDTVHAGNIDTFRNCTVLEGSLTILDSTFNGFQQIYQNFTFGPRYPAMDPSKLEVFGTLKEVTGYINIQAHHPRFTNLSAFSN 1321 HSP 2 Score: 65.0846 bits (157), Expect = 5.789e-10 Identity = 66/251 (26.29%), Postives = 105/251 (41.83%), Query Frame = 0 Query: 387 NEVMHAGNI-DSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFS-----ALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSP-SHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEP--LAGKAICRPCHSLCK-KCNGYGFHDDVCQECVHFSQDQQCVPEC 627 N H N+ D + NCT ++G++ + Q+ + +F ++EVTGY+ I H + + + +L+++ GRTL + AL + + + +L + +LR I G+V IL N +LC+ + I W +I+ + + N K P+ R C C GCWG G N+C K + G CH C C G D C C +F D C EC Sbjct: 194 NREHHYRNLRDRYTNCTYVDGNLEL-----TWLQDENLDLSF--------------LEHIREVTGYVLIS--HVDVRRI-ILPSLQIVRGRTLFKLTVQDDEFALIVTLSKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEIITGQNARYVYVYNFKEPE---RDCTPCHESCE-NGCWGEGPNNCQKFSKINCAAQCHSGRCFGPKPRECCHLFCAGGCTGPKQSD--CLACKNFYDDGVCKQEC 862
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816142|gb|GAXK01138426.1| (TSA: Calanus finmarchicus comp102350_c1_seq6 transcribed RNA sequence) HSP 1 Score: 457.218 bits (1175), Expect = 6.766e-153 Identity = 207/255 (81.18%), Postives = 231/255 (90.59%), Query Frame = 0 Query: 215 WEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRN 469 W+EIITG +YVYVYNF EPERDCTPCHESC++GCWGEGP+NCQKFSKINC+ QCH GRCFG PRECCHLFCAGGCTGPKQSDCLAC+NF+DDGV K ECPPMQ YNPIKY+WE++P+GKYAYGATCVKECP+HLLKDNGACVR CPPKKK V+GECVPCDGPCPK CHF + +HAGNID+F+NCTV+EGS+TILDSTFNGFQ+ Y+N+TFG RYPAMDP KLEVF TLKEVTGYINIQ HHP F NL+AF N Sbjct: 1 WDEIITGQNARYVYVYNFKEPERDCTPCHESCENGCWGEGPNNCQKFSKINCAAQCHSGRCFGPKPRECCHLFCAGGCTGPKQSDCLACKNFYDDGVCKQECPPMQIYNPIKYKWERDPQGKYAYGATCVKECPEHLLKDNGACVRACPPKKKAVDGECVPCDGPCPKICHFTDTVHAGNIDTFRNCTVLEGSLTILDSTFNGFQQIYQNFTFGPRYPAMDPSKLEVFGTLKEVTGYINIQAHHPRFTNLSAFSN 765
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816157|gb|GAXK01138411.1| (TSA: Calanus finmarchicus comp102350_c0_seq7 transcribed RNA sequence) HSP 1 Score: 443.736 bits (1140), Expect = 7.772e-148 Identity = 201/246 (81.71%), Postives = 224/246 (91.06%), Query Frame = 0 Query: 224 GKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRN 469 +YVYVYNF EPERDCTPCHESC++GCWGEGP+NCQKFSKINC+ QCH GRCFG PRECCHLFCAGGCTGPKQSDCLAC+NF+DDGV K ECPPMQ YNPIKY+WE++P+GKYAYGATCVKECP+HLLKDNGACVR CPPKKK V+GECVPCDGPCPK CHF + +HAGNID+F+NCTV+EGS+TILDSTFNGFQ+ Y+N+TFG RYPAMDP KLEVF TLKEVTGYINIQ HHP F NL+AF N Sbjct: 3 ARYVYVYNFKEPERDCTPCHESCENGCWGEGPNNCQKFSKINCAAQCHSGRCFGPKPRECCHLFCAGGCTGPKQSDCLACKNFYDDGVCKQECPPMQIYNPIKYKWERDPQGKYAYGATCVKECPEHLLKDNGACVRACPPKKKAVDGECVPCDGPCPKICHFTDTVHAGNIDTFRNCTVLEGSLTILDSTFNGFQQIYQNFTFGPRYPAMDPSKLEVFGTLKEVTGYINIQAHHPRFTNLSAFSN 740
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816152|gb|GAXK01138416.1| (TSA: Calanus finmarchicus comp102350_c0_seq12 transcribed RNA sequence) HSP 1 Score: 325.865 bits (834), Expect = 1.084e-103 Identity = 147/182 (80.77%), Postives = 166/182 (91.21%), Query Frame = 0 Query: 292 CTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVI 473 CTGPKQSDCLAC+NF+DDGV K ECPPMQ YNPIKY+WE++P+GKYAYGATCVKECP+HLLKDNGACVR CPPKKK V+GECVPCDGPCPK CHF + +HAGNID+F+NCTV+EGS+TILDSTFNGFQ+ Y+N+TFG RYPAMDP KLEVF TLKEVTGYINIQ HHP F NL+AF NLEV+ Sbjct: 1 CTGPKQSDCLACKNFYDDGVCKQECPPMQIYNPIKYKWERDPQGKYAYGATCVKECPEHLLKDNGACVRACPPKKKAVDGECVPCDGPCPKICHFTDTVHAGNIDTFRNCTVLEGSLTILDSTFNGFQQIYQNFTFGPRYPAMDPSKLEVFGTLKEVTGYINIQAHHPRFTNLSAFSNLEVV 546
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816153|gb|GAXK01138415.1| (TSA: Calanus finmarchicus comp102350_c0_seq11 transcribed RNA sequence) HSP 1 Score: 325.865 bits (834), Expect = 1.084e-103 Identity = 147/182 (80.77%), Postives = 166/182 (91.21%), Query Frame = 0 Query: 292 CTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVI 473 CTGPKQSDCLAC+NF+DDGV K ECPPMQ YNPIKY+WE++P+GKYAYGATCVKECP+HLLKDNGACVR CPPKKK V+GECVPCDGPCPK CHF + +HAGNID+F+NCTV+EGS+TILDSTFNGFQ+ Y+N+TFG RYPAMDP KLEVF TLKEVTGYINIQ HHP F NL+AF NLEV+ Sbjct: 1 CTGPKQSDCLACKNFYDDGVCKQECPPMQIYNPIKYKWERDPQGKYAYGATCVKECPEHLLKDNGACVRACPPKKKAVDGECVPCDGPCPKICHFTDTVHAGNIDTFRNCTVLEGSLTILDSTFNGFQQIYQNFTFGPRYPAMDPSKLEVFGTLKEVTGYINIQAHHPRFTNLSAFSNLEVV 546
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816155|gb|GAXK01138413.1| (TSA: Calanus finmarchicus comp102350_c0_seq9 transcribed RNA sequence) HSP 1 Score: 279.641 bits (714), Expect = 2.854e-86 Identity = 129/144 (89.58%), Postives = 141/144 (97.92%), Query Frame = 0 Query: 78 HGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITG 221 HGKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFL+HIREVTGYVLISHVDVR+I+LPSLQI+RGRTLFKL+V+DD+F+L+VTLSKMH LEMPALRDIL GSVGILNNYNLCHIKTI+W+EIITG Sbjct: 4 HGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLEHIREVTGYVLISHVDVRRIILPSLQIVRGRTLFKLTVQDDEFALIVTLSKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEIITG 435 HSP 2 Score: 48.521 bits (114), Expect = 2.367e-5 Identity = 35/138 (25.36%), Postives = 67/138 (48.55%), Query Frame = 0 Query: 396 DSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFS-----ALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIM 528 D + NCT ++G++ + Q+ + +F ++EVTGY+ I H + + + +L+++ GRTL + AL + + + +L + +LR I G+V IL N +LC+ + I W +I+ Sbjct: 10 DRYTNCTYVDGNLEL-----TWLQDENLDLSF--------------LEHIREVTGYVLIS--HVDVRRI-ILPSLQIVRGRTLFKLTVQDDEFALIVTLSKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEII 357
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816156|gb|GAXK01138412.1| (TSA: Calanus finmarchicus comp102350_c0_seq8 transcribed RNA sequence) HSP 1 Score: 279.641 bits (714), Expect = 2.854e-86 Identity = 129/144 (89.58%), Postives = 141/144 (97.92%), Query Frame = 0 Query: 78 HGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITG 221 HGKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFL+HIREVTGYVLISHVDVR+I+LPSLQI+RGRTLFKL+V+DD+F+L+VTLSKMH LEMPALRDIL GSVGILNNYNLCHIKTI+W+EIITG Sbjct: 4 HGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLEHIREVTGYVLISHVDVRRIILPSLQIVRGRTLFKLTVQDDEFALIVTLSKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEIITG 435 HSP 2 Score: 48.521 bits (114), Expect = 2.367e-5 Identity = 35/138 (25.36%), Postives = 67/138 (48.55%), Query Frame = 0 Query: 396 DSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFS-----ALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIM 528 D + NCT ++G++ + Q+ + +F ++EVTGY+ I H + + + +L+++ GRTL + AL + + + +L + +LR I G+V IL N +LC+ + I W +I+ Sbjct: 10 DRYTNCTYVDGNLEL-----TWLQDENLDLSF--------------LEHIREVTGYVLIS--HVDVRRI-ILPSLQIVRGRTLFKLTVQDDEFALIVTLSKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEII 357
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816158|gb|GAXK01138410.1| (TSA: Calanus finmarchicus comp102350_c0_seq6 transcribed RNA sequence) HSP 1 Score: 280.796 bits (717), Expect = 8.855e-85 Identity = 129/144 (89.58%), Postives = 141/144 (97.92%), Query Frame = 0 Query: 78 HGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITG 221 HGKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFL+HIREVTGYVLISHVDVR+I+LPSLQI+RGRTLFKL+V+DD+F+L+VTLSKMH LEMPALRDIL GSVGILNNYNLCHIKTI+W+EIITG Sbjct: 3 HGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLEHIREVTGYVLISHVDVRRIILPSLQIVRGRTLFKLTVQDDEFALIVTLSKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEIITG 434 HSP 2 Score: 47.3654 bits (111), Expect = 1.354e-4 Identity = 39/138 (28.26%), Postives = 70/138 (50.72%), Query Frame = 0 Query: 396 DSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFS-----ALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIM 528 D + NCT ++G++ + Q+ EN +D LE ++EVTGY+ I H + + + +L+++ GRTL + AL + + + +L + +LR I G+V IL N +LC+ + I W +I+ Sbjct: 9 DRYTNCTYVDGNLEL-----TWLQD--EN---------LDLSFLE---HIREVTGYVLIS--HVDVRRI-ILPSLQIVRGRTLFKLTVQDDEFALIVTLSKMHNLEMPALRDILRGSVGILNNYNLCHIKTIQWDEII 356
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816139|gb|GAXK01138429.1| (TSA: Calanus finmarchicus comp102350_c1_seq9 transcribed RNA sequence) HSP 1 Score: 210.305 bits (534), Expect = 6.337e-62 Identity = 92/103 (89.32%), Postives = 102/103 (99.03%), Query Frame = 0 Query: 78 HGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTL 180 HGKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFL+HIREVTGYVLISHVDVR+I+LPSLQI+RGRTLFKL+V+DD+F+L+VTL Sbjct: 151 HGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLEHIREVTGYVLISHVDVRRIILPSLQIVRGRTLFKLTVQDDEFALIVTL 459
BLAST of EMLSAG00000007374 vs. C. finmarchicus
Match: gi|592816143|gb|GAXK01138425.1| (TSA: Calanus finmarchicus comp102350_c1_seq5 transcribed RNA sequence) HSP 1 Score: 210.69 bits (535), Expect = 1.162e-59 Identity = 92/103 (89.32%), Postives = 102/103 (99.03%), Query Frame = 0 Query: 78 HGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTL 180 HGKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFL+HIREVTGYVLISHVDVR+I+LPSLQI+RGRTLFKL+V+DD+F+L+VTL Sbjct: 717 HGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLEHIREVTGYVLISHVDVRRIILPSLQIVRGRTLFKLTVQDDEFALIVTL 1025
BLAST of EMLSAG00000007374 vs. L. salmonis peptides
Match: EMLSAP00000007374 (pep:novel supercontig:LSalAtl2s:LSalAtl2s41:164202:216377:-1 gene:EMLSAG00000007374 transcript:EMLSAT00000007374 description:"maker-LSalAtl2s41-augustus-gene-2.12") HSP 1 Score: 1934.07 bits (5009), Expect = 0.000e+0 Identity = 937/937 (100.00%), Postives = 937/937 (100.00%), Query Frame = 0 Query: 1 MXLPLLIALLLSIHLPGATPLEEKGIMSIIFIHPPQFTKMRILLLLLCIVLWKNPSPVEASSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRGCYGMGPDKCLACKNYKVYLTGEFPEDDNVDSMPNPSTSTLQHNNSHKSTLPLGSTSNVNSNNTLSRRQVNGLRLNLPMDDEEYLVPSPHSPHSAAAAAQQSNTTPNNNINNNTNAYMDLISDPKNPTMFPYPPPQGYFLTDNPPNYGRVPDFVDSSSTSSGNPNLTGRIGDYHTLGIPFIPNSPSSSQGGPPSIAGSTASYPMPPPVSTASLVVAAGSSAXSTPPATQQQPSSAGLNGVINGYCRSSNPPRSSGEESDDHDYYNDFERLNRELQPLHPRNTLPSKHETTV 937 MXLPLLIALLLSIHLPGATPLEEKGIMSIIFIHPPQFTKMRILLLLLCIVLWKNPSPVEASSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRGCYGMGPDKCLACKNYKVYLTGEFPEDDNVDSMPNPSTSTLQHNNSHKSTLPLGSTSNVNSNNTLSRRQVNGLRLNLPMDDEEYLVPSPHSPHSAAAAAQQSNTTPNNNINNNTNAYMDLISDPKNPTMFPYPPPQGYFLTDNPPNYGRVPDFVDSSSTSSGNPNLTGRIGDYHTLGIPFIPNSPSSSQGGPPSIAGSTASYPMPPPVSTASLVVAAGSSAXSTPPATQQQPSSAGLNGVINGYCRSSNPPRSSGEESDDHDYYNDFERLNRELQPLHPRNTLPSKHETTV Sbjct: 1 MXLPLLIALLLSIHLPGATPLEEKGIMSIIFIHPPQFTKMRILLLLLCIVLWKNPSPVEASSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRGCYGMGPDKCLACKNYKVYLTGEFPEDDNVDSMPNPSTSTLQHNNSHKSTLPLGSTSNVNSNNTLSRRQVNGLRLNLPMDDEEYLVPSPHSPHSAAAAAQQSNTTPNNNINNNTNAYMDLISDPKNPTMFPYPPPQGYFLTDNPPNYGRVPDFVDSSSTSSGNPNLTGRIGDYHTLGIPFIPNSPSSSQGGPPSIAGSTASYPMPPPVSTASLVVAAGSSAXSTPPATQQQPSSAGLNGVINGYCRSSNPPRSSGEESDDHDYYNDFERLNRELQPLHPRNTLPSKHETTV 937
BLAST of EMLSAG00000007374 vs. L. salmonis peptides
Match: EMLSAP00000002641 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1534:13768:20494:-1 gene:EMLSAG00000002641 transcript:EMLSAT00000002641 description:"maker-LSalAtl2s1534-augustus-gene-0.16") HSP 1 Score: 87.4261 bits (215), Expect = 1.134e-17 Identity = 89/370 (24.05%), Postives = 166/370 (44.86%), Query Frame = 0 Query: 78 HGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDE-----NLDLSFLQHIREVTGYVLISHVDVRK---IVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTP-CHESC--------QSGCWGEGPSNCQKFSKINCSP--QCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXEC-----PPMQRYNP-IKYRWEKNPEGKYAYGATCVKECPKHLLKD------NGACVRICP------PKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITI 410 +IC TK + + + + ++ L NCT ++G+L + + + + LSF + +RE+T + ++ + + + + P+L +IRG L V + F +++ + ++ + + +L IL G V I N LC++ TI W+ I+ G G ++++ NE C+ C + C + CW + F+ I C C++G E C C GGC GP Q +C +C++F K C P +N I ++ E Y + E K + ++ N +C++ CP K+T + C C+ CPK C ++ ++ ++ CT I+G ++I Sbjct: 233 QSEICGNTK--IKIMGDLQRDFKALE----NCTIIEGHLAIYDIAEVEPSALSRKLSFPK-LREITDFFIMYNANAFESLATLFPNLTVIRGDDL----VMNYAF-VVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEG-FIHIQR-NENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFA-IPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQDNSKNYCRTTCPSPFLMFNDWICIDIKECRENSYIVNEKSITE--KSITREMKYRIYNDSCIKGCPLGTQQITNKETRDLTCEKCEF-CPKVCPGGKIRSLDDLHQYKECTHIDGDLSI 584 HSP 2 Score: 64.3142 bits (155), Expect = 1.352e-10 Identity = 62/234 (26.50%), Postives = 90/234 (38.46%), Query Frame = 0 Query: 394 NIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNL-NAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQEC---------IRQDHM-------------------CD----------------PQCSAE---GCWGPGNNSCLSCKKFQTQ 579 + + +NCT+IEG + I Y P+ +KL F L+E+T + I + F++L F NL VI G L ++ + I L +GL+SL I G V I N LCY INW I+ +Q N+N C + ++H+ C+ +CS E GC+GP C SCK F Q Sbjct: 251 DFKALENCTIIEGHLAI--------------YDIAEVEPSALSRKLS-FPKLREITDFF-IMYNANAFESLATLFPNLTVIRGDDLVMNYAFVVIYCNNLYEIGLRSLTHILRGGVRIEFNTRLCYVHTINWDMIVVGSEGFIHIQRNENRNVCSDYCRDDCPLLKNHLTRRACWTKATVKEVTFAIPCEEGLTCYQGNDGTRGSIEKCSKECLGGCYGPSQEECYSCKHFLWQ 468
BLAST of EMLSAG00000007374 vs. L. salmonis peptides
Match: EMLSAP00000012868 (pep:novel supercontig:LSalAtl2s:LSalAtl2s97:2839025:2843929:-1 gene:EMLSAG00000012868 transcript:EMLSAT00000012868 description:"augustus_masked-LSalAtl2s97-processed-gene-28.2") HSP 1 Score: 52.373 bits (124), Expect = 5.871e-7 Identity = 28/78 (35.90%), Postives = 40/78 (51.28%), Query Frame = 0 Query: 591 CRPCHSLCKKCNGYGFHDDVCQECVH--FSQDQQCVPECDGDYYKD-STKCKPCSEECRGCYGMGPDKCLACKNYKVY 665 CRPCH CK C +G +D C C + C G+YY D + KC C CR C+G ++CL+C N++ + Sbjct: 957 CRPCHGRCKTC--FGQENDNCLSCFKGLLFEGSTCWACKSGEYYDDIAAKCLKCHLSCRQCFGDLANECLSCNNHRAF 1032
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|6175066|sp|P04412.3|EGFR_DROME (RecName: Full=Epidermal growth factor receptor; Short=Egfr; AltName: Full=Drosophila relative of ERBB; AltName: Full=Gurken receptor; AltName: Full=Protein torpedo; Flags: Precursor) HSP 1 Score: 743.806 bits (1919), Expect = 0.000e+0 Identity = 354/595 (59.50%), Postives = 424/595 (71.26%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTE-YFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLAG---------KAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRGCYG----MGPDKCLAC 659 GKICIGTK R+SVP+N+EHHYRNLRDRYTNCTYVDGNL+LTWL +ENLDLSFL +IREVTGY+LISHVDV+K+V P LQIIRGRTLF LSV ++K++L VT SKM+ LE+P LRD+L G VG NNYNLCH++TI+W EI++ Y Y Y+F PER+C CHESC GCWGEGP NCQKFSK+ CSPQC GRC+G PRECCHLFCAGGCTGP Q DC+AC+NFFD+ V K ECPPM++YNP Y E NPEGKYAYGATCVKECP HLL+DNGACVR CP K GECVPC+GPCPKTC V+HAGNIDSF+NCTVI+G+I ILD TF+GFQ+ Y NYT G RY +DP++ EVF+T+KE+TGY+NI+G HP F+NL+ FRNLE I GR L E F+AL IVK++L SL +++L++I SG+V I N+DLCY I W I K P + N C + +C QC+ +GCWG G + CL+CK F G G C+ CH C+ CNG G D CQECVH Q CV EC + Y D C+ C C GC G +G C C Sbjct: 99 GKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVTYSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAY-YNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGECVPCNGPCPKTCPGVTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYISNAYKFDNRTCKICHPECRTCNGAGA--DHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTC 690 HSP 2 Score: 98.2117 bits (243), Expect = 1.818e-19 Identity = 43/95 (45.26%), Postives = 60/95 (63.16%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYLTGE 669 Q QG L+PLAG+A+CR CH LC+ C YG+H+ VC +C H+ + +QC EC D+Y D + C EC GC G G D C +C+N+K++ E Sbjct: 723 QEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANE 817
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|338818034|sp|P0CY46.1|EGFR_APIME (RecName: Full=Epidermal growth factor receptor; Short=Egfr) HSP 1 Score: 629.402 bits (1622), Expect = 0.000e+0 Identity = 305/487 (62.63%), Postives = 358/487 (73.51%), Query Frame = 0 Query: 201 ILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----TQGKLEP---LAGKAICRPCHSLCKKCNG--YGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPE 672 + NNYNLCHI+TI WEEIITGP Y YVYNF PER CTPC +SC+ GCWGEGP NCQK+SK NCSPQC +GRCFG PRECCHLFCAGGCTGPKQSDC+AC+NFFDDGV ECPPMQ+YNP Y WE NP+GKYAYGATCV+ CP+HLLKDNGACVR CPPKKK +NGECVPCDGPCPKTC E +H+GNIDSF++CT+IEGSITILD +F GFQ Y N++FG RY M P KLEVF+TLKE+TG++NIQG H +FKNL+ FRNLEVIGGRTLTEYF++LY+VKT+L S GL SL+KI SG+++ILENK+LCYAQ INW +I KS H +LL NN+N ECI+ +CD QCS EGCWGPG CLSCK F Q P A + C+ CH ++C+G G + D C++C H CVPEC Y D+ CK C C GC G +GP+ C +C K L PE Sbjct: 1 MYNNYNLCHIRTINWEEIITGPSAMYSYVYNFTSPERACTPCDKSCEQGCWGEGPENCQKYSKTNCSPQCWQGRCFGPNPRECCHLFCAGGCTGPKQSDCIACKNFFDDGVCTQECPPMQKYNPTTYSWEPNPDGKYAYGATCVRRCPEHLLKDNGACVRSCPPKKKALNGECVPCDGPCPKTCKGVEKVHSGNIDSFKDCTIIEGSITILDQSFQGFQHVYRNFSFGKRYEKMHPDKLEVFSTLKEITGFLNIQGDHKDFKNLSYFRNLEVIGGRTLTEYFASLYVVKTSLVSFGLSSLKKIYSGSIAILENKNLCYAQSINWTRIKKSSEHESLLSNNRNESECIKDGLVCDEQCSDEGCWGPGPAQCLSCKNFILGNDCLQDCTAPGIYQADEKTCKVCH---EECDGSCIGPNTDHCKKCKHARDGPFCVPECPASKYNDNGVCKSCHGNCVGGCEGPENNIGPNGCHSCD--KAILNDHVPE 482 HSP 2 Score: 122.094 bits (305), Expect = 7.649e-27 Identity = 52/89 (58.43%), Postives = 66/89 (74.16%), Query Frame = 0 Query: 579 QGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK-CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 QG L+PLA KA+CR CHS CKKC GYGFH+ VCQEC + + +QC EC DY+ D+ K C PC ECRGC+G GP++C C+NYK+Y+ Sbjct: 505 QGPLKPLASKAVCRKCHSRCKKCTGYGFHEHVCQECTKYKRGEQCEDECPADYFADANKLCIPCFSECRGCFGPGPNQCYKCRNYKIYI 593 HSP 3 Score: 88.9669 bits (219), Expect = 1.108e-16 Identity = 77/275 (28.00%), Postives = 109/275 (39.64%), Query Frame = 0 Query: 128 LSFLQHIREVTGYVLI--SHVDVRKI-VLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPE--RDCTPCHESC-QSGCWGEGPSNCQKFSKI----NCSPQCHKGRCFGELPREC--CHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECV-PCDGP----CPKTCH 385 L ++E+TG++ I H D + + +L++I GRTL + SL V + + + +L+ I GS+ IL N NLC+ ++I W I + + N NE E +D C E C GCWG GP+ C +C C + + C CH C G C GP C C++ D G CV ECP DNG C K+ +G CV C+GP P CH Sbjct: 239 LEVFSTLKEITGFLNIQGDHKDFKNLSYFRNLEVIGGRTLTEYFA-----SLYVVKTSLVSFGLSSLKKIYSGSIAILENKNLCYAQSINWTRIKKSSEHESLLSNNRNESECIKDGLVCDEQCSDEGCWGPGPAQCLSCKNFILGNDCLQDCTAPGIYQADEKTCKVCHEECDGSCIGPNTDHCKKCKHARD-------------------------------GPFCVPECPASKYNDNGVC--------KSCHGNCVGGCEGPENNIGPNGCH 469
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|119223|sp|P13387.1|EGFR_CHICK (RecName: Full=Epidermal growth factor receptor; Short=CER; Flags: Precursor) HSP 1 Score: 417.927 bits (1073), Expect = 1.026e-132 Identity = 251/629 (39.90%), Postives = 344/629 (54.69%), Query Frame = 0 Query: 80 KICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHY--------LEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESC-QSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECP-KHLLKDNGACVRICPPKKKTV--NG--ECVPCDGPCPKTCHFNEV--------MHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCKKCNGYGFHD-------DVCQECVHFSQDQQCVPECDG-----------DYYKDSTKCKPCSEEC-RGCYGMGPDKC 656 K+C GT +++ + E H+ +L+ Y NC V NLE+T+++ N DL+FL+ I+EV GYVLI+ V I L +LQIIRG L+ D+ F+L V LS H L M L +IL G V I NN LC++ T+ W +II R K + V +F C CH +C + CWG G NCQ +K+ C+ QC GRC G++P +CCH CA GCTGP++SDCLACR F DD K CPP+ YNP Y+ + NPEGKY++GATCV+ECP +++ D+G+CVR C V NG +C CDG C K C+ + ++A NIDSF+NCT I G ++IL F G F P +DPKKL+VF T+KE++G++ IQ N +L AF NLE+I GRT +L +V + SLGL+SL++I G ++I++NK+LCYA +NW+ + + S T + N+N +C H+CDP CS GCWGPG C SC+ F QG+ + C PCHS C N ++ D C +C HF CV C Y + C+ C C RGC G G + C Sbjct: 35 KVCQGTNNKLTQLGHVEDHFTSLQRMYNNCEVVLSNLEITYVE-HNRDLTFLKTIQEVAGYVLIALNMVDVIPLENLQIIRGNVLY-----DNSFALAV-LSNYHMNKTQGLRELPMKRLSEILNGGVKISNNPKLCNMDTVLWNDIIDTSR-KPLTVLDFASNLSSCPKCHPNCTEDHCWGAGEQNCQTLTKVICAQQC-SGRCRGKVPSDCCHNQCAAGCTGPRESDCLACRKFRDDATCKDTCPPLVLYNPTTYQMDVNPEGKYSFGATCVRECPHNYVVTDHGSCVRSCNTDTYEVEENGVRKCKKCDGLCSKVCNGIGIGELKGILSINATNIDSFKNCTKINGDVSILPVAFLG-------DAFTKTLP-LDPKKLDVFRTVKEISGFLLIQAWPDNATDLYAFENLEIIRGRTKQHGQYSLAVVNLKIQSLGLRSLKEISDGDIAIMKNKNLCYADTMNWRSLFATQSQKTKIIQNRNKNDCTADRHVCDPLCSDVGCWGPGPFHCFSCRFFSRQKECVKQCNILQGEPREFERDSKCLPCHSECLVQNSTAYNTTCSGPGPDHCMKCAHFIDGPHCVKACPAGVLGENDTLVWKYADANAVCQLCHPNCTRGCKGPGLEGC 646
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|75041961|sp|Q5RB22.1|ERBB3_PONAB (RecName: Full=Receptor tyrosine-protein kinase erbB-3; AltName: Full=Proto-oncogene-like protein c-ErbB-3; Flags: Precursor) HSP 1 Score: 427.172 bits (1097), Expect = 5.848e-130 Identity = 240/625 (38.40%), Postives = 334/625 (53.44%), Query Frame = 0 Query: 81 ICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCK------KCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 +C GT +SV + E+ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L + L +IL G V I N LCH+ TI+W +I+ + V N + C PCHE C+ CWG GP +CQ +K C+PQC+ G CFG P +CCH CAGGC+GP+ +DC ACR+F D G CP YN + ++ E NP KY YG CV CP + + D +CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + NG ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G + I N+ LCY +NW K+++ P+ L +++N+ ++C+ + +CDP CS+ GCWGPG CLSC+ + G+ A +A C CH C+ CNG G D C +C HF CV C G YK +C+PC E C +GC G CL Sbjct: 28 VCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDN----GKSCPPCHEVCKGRCWGSGPEDCQTLTKTICAPQCN-GHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLNG--------DPWHKIPALDPEKLNVFQTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSG--SDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQGCKGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|119534|sp|P21860.1|ERBB3_HUMAN (RecName: Full=Receptor tyrosine-protein kinase erbB-3; AltName: Full=Proto-oncogene-like protein c-ErbB-3; AltName: Full=Tyrosine kinase-type cell surface receptor HER3; Flags: Precursor) HSP 1 Score: 424.861 bits (1091), Expect = 4.712e-129 Identity = 243/632 (38.45%), Postives = 336/632 (53.16%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCK------KCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 NSQ +C GT +SV + E+ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L + L +IL G V I N LCH+ TI+W +I+ + V N R C PCHE C+ CWG G +CQ +K C+PQC+ G CFG P +CCH CAGGC+GP+ +DC ACR+F D G CP YN + ++ E NP KY YG CV CP + + D +CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + NG ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G + I N+ LCY +NW K+++ P+ L +++N+ ++C+ + +CDP CS+ GCWGPG CLSC+ + G+ A +A C CH C+ CNG G D C +C HF CV C G YK +C+PC E C +GC G CL Sbjct: 24 NSQ---AVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDN----GRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCN-GHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLNG--------DPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSG--SDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQGCKGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|77416857|sp|Q61526.2|ERBB3_MOUSE (RecName: Full=Receptor tyrosine-protein kinase erbB-3; AltName: Full=Glial growth factor receptor; AltName: Full=Proto-oncogene-like protein c-ErbB-3; Flags: Precursor) HSP 1 Score: 421.779 bits (1083), Expect = 5.963e-128 Identity = 244/632 (38.61%), Postives = 333/632 (52.69%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCK------KCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 NSQ +C GT +SV + ++ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L L +IL G V I N LCH+ TI+W +I+ P + V N +C PCHE C+ CWG GP +CQ +K C+PQC+ GRCFG P +CCH CAGGC+GP+ +DC ACR+F D G CP YN + ++ E NP KY YG CV CP + + D CVR CP K V+ C PC G CPK C + + + NID F NCT I G++ L + NG ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G V I N+ LCY +NW ++++ P+ L ++ N+ EC+ + +CDP CS+ GCWGPG CLSC+ + QG+ +A C CH C+ CNG G D C C HF CV C G YK +C+PC E C +GC G CL Sbjct: 24 NSQ---AVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVKNNGG----NCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCN-GRCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQTFCVRACPADKMEVDKNGLKMCEPCRGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGLNG--------DPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPAEERLDIKYNRPLGECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEPREFVHEAHCFSCHPECQPMEGTSTCNGSG--SDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCKGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|21431758|sp|Q62799.3|ERBB3_RAT (RecName: Full=Receptor tyrosine-protein kinase erbB-3; AltName: Full=Proto-oncogene-like protein c-ErbB-3; Flags: Precursor) HSP 1 Score: 420.624 bits (1080), Expect = 1.526e-127 Identity = 245/632 (38.77%), Postives = 333/632 (52.69%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCHFN------EVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTL-TEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLC------KKCNGYGFHDDVCQECVHFSQDQQCVPEC-------DGDYYK---DSTKCKPCSEEC-RGCYGMGPDKCLA 658 NSQ +C GT +SV + ++ Y+ L Y C V GNLE+ L N DLSFLQ IREVTGYVL++ + + LP+L+++RG ++ D KF++ V L+ + L+ L +IL G V I N LCH+ TI+W +I+ RG + V N +C PCHE C+ CWG GP +CQ +K C+PQC+ GRCFG P +CCH CAGGC+GP+ +DC ACR F D G CP YN + ++ E NP KY YG CV CP + + D CVR CPP K V+ C PC G CPK C + + + NID F NCT I G++ L + N ++ PA+DP+KL VF T++E+TGY+NIQ P+ N + F NL IGGR+L FS L + +TSLG +SL++I +G V I N+ LCY +NW ++++ PS L ++ ++ EC+ + +CDP CS+ GCWGPG CLSC+ + QG+ +A C CH C CNG G D C C HF CV C G YK +C+PC E C +GC G CL Sbjct: 24 NSQ---AVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLKFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVR-VRGAEIVVKNNGA---NCPPCHEVCKGRCWGPGPDDCQILTKTICAPQCN-GRCFGPNPNQCCHDECAGGCSGPQDTDCFACRRFNDSGACVPRCPEPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTFCVRACPPDKMEVDKHGLKMCEPCGGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGL--------NVDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPSEERLDIKYDRPLGECLAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNFLQGEPREFVHEAQCFSCHPECLPMEGTSTCNGSG--SDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCNGPELQDCLG 631
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|1352359|sp|Q01279.1|EGFR_MOUSE (RecName: Full=Epidermal growth factor receptor; Flags: Precursor) HSP 1 Score: 403.675 bits (1036), Expect = 2.678e-122 Identity = 240/630 (38.10%), Postives = 345/630 (54.76%), Query Frame = 0 Query: 80 KICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMV------TLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERD----CTPCHESCQSG-CWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPK-HLLKDNGACVRICPPKKKTVNGE----CVPCDGPCPKTCH------FNEVM--HAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----------TQGKLEPLAGKAICRPCHSLCK------KCNGYGFHDDVCQECVHFSQDQQCVPECDG-----------DYYKDSTKCKPCSEECR-GCYGMGPDKC 656 K+C GT R++ E H+ +L+ Y NC V GNLE+T++Q N DLSFL+ I+EV GYVLI+ V +I L +LQIIRG L+ ++ ++L + + + L M L++IL G+V NN LC++ TI+W +I+ + V++ N + + C C SC +G CWG G NCQK +KI C+ QC RC G P +CCH CA GCTGP++SDCL C+ F D+ K CPP+ YNP Y+ + NPEGKY++GATCVK+CP+ +++ D+G+CVR C P V + C CDGPC K C+ F + + +A NI F+ CT I G + IL F G +++T R P +DP++LE+ T+KE+TG++ IQ N+ +L+AF NLE+I GRT +L +V +TSLGL+SL++I G V I N++LCYA INW+K+ +P+ T + NN+ ++C +H+C+P CS+EGCWGP C+SC+ +G+ + C CH C C G G D C +C H+ CV C Y + C C C GC G G C Sbjct: 29 KVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQ-RNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALY-----ENTYALAILSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIV-----QNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSH-RCRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKG-----DSFT---RTPPLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRG--PDNCIQCAHYIDGPHCVKTCPAGIMGENNTLVWKYADANNVCHLCHANCTYGCAGPGLQGC 636
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|374095519|sp|Q61527.5|ERBB4_MOUSE (RecName: Full=Receptor tyrosine-protein kinase erbB-4; AltName: Full=Proto-oncogene-like protein c-ErbB-4; Contains: RecName: Full=ERBB4 intracellular domain; Short=4ICD; Short=E4ICD; AltName: Full=s80HER4; Flags: Precursor) HSP 1 Score: 394.43 bits (1012), Expect = 4.044e-118 Identity = 228/625 (36.48%), Postives = 331/625 (52.96%), Query Frame = 0 Query: 81 ICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTV--NG--ECVPCDGPCPKTCH--------FNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQT-----------QGKLEPLAGKAICRPCHSLCKK-------CNGYGFHDDVCQECVHFSQDQQCVPEC-DG---------DYYKDSTKCKPCSEEC-RGCYGMGPDKCL 657 +C GT+ ++S ++ E YR LR Y NC V GNLE+T ++ N DLSFL+ IREVTGYVL++ R + L +L+IIRG L+ +D+++L + L+ + L + L +IL G V + N LC+ TI W++I+ P + + + N C CH+SC CWG ++CQ ++ C+ QC GRC+G +CCH CAGGC+GPK +DC AC NF D G +CP YNP ++ E N KY YGA CVK+CP + + D+ +CVR CP K V NG C PC CPK C + + + NID F NCT I G++ L + +G + Y N A+DP+KL VF T++E+TG++NIQ PN + + F NL IGGR L S L + + +TSL +SL++I +G + I +N +LCY INW + + + ++++N+ + C + +C+ CS +GCWGPG + CLSC++F G+ +IC C S C+K C+G G D C +C HF CV +C DG Y +C PC C +GC G C+ Sbjct: 28 VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIE-HNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLY-----EDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTNG-SSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQC-DGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--DPY------NAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPG--PDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADQDRECHPCHPNCTQGCNGPTSHDCI 634
BLAST of EMLSAG00000007374 vs. SwissProt
Match: gi|3913590|sp|Q15303.1|ERBB4_HUMAN (RecName: Full=Receptor tyrosine-protein kinase erbB-4; AltName: Full=Proto-oncogene-like protein c-ErbB-4; AltName: Full=Tyrosine kinase-type cell surface receptor HER4; AltName: Full=p180erbB4; Contains: RecName: Full=ERBB4 intracellular domain; Short=4ICD; Short=E4ICD; AltName: Full=s80HER4; Flags: Precursor) HSP 1 Score: 391.734 bits (1005), Expect = 3.226e-117 Identity = 226/625 (36.16%), Postives = 331/625 (52.96%), Query Frame = 0 Query: 81 ICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLS-------KMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTV--NG--ECVPCDGPCPKTCH--------FNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQT-----------QGKLEPLAGKAICRPCHSLCKK-------CNGYGFHDDVCQECVHFSQDQQCVPEC-DG---------DYYKDSTKCKPCSEEC-RGCYGMGPDKCL 657 +C GT+ ++S ++ E YR LR Y NC V GNLE+T ++ N DLSFL+ +REVTGYVL++ R + L +L+IIRG L+ +D+++L + L+ + L + L +IL G V + N LC+ TI W++I+ P + + + N C CH+SC CWG ++CQ ++ C+ QC GRC+G +CCH CAGGC+GPK +DC AC NF D G +CP YNP ++ E N KY YGA CVK+CP + + D+ +CVR CP K V NG C PC CPK C + + + NID F NCT I G++ L + +G + Y N A+DP+KL VF T++E+TG++NIQ PN + + F NL IGGR L S L + + +TSL +SL++I +G + I +N +LCY INW + + + ++++N+ + C + +C+ CS++GCWGPG + CLSC++F G+ +IC C C+K C+G G D C +C HF CV +C DG Y +C PC C +GC G C+ Sbjct: 28 VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIE-HNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLY-----EDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNG-SSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQC-DGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--DPY------NAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPG--PDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCI 634
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: XP_006560089.2 (PREDICTED: epidermal growth factor receptor [Apis mellifera]) HSP 1 Score: 824.313 bits (2128), Expect = 0.000e+0 Identity = 397/609 (65.19%), Postives = 465/609 (76.35%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQ-----TQGKLEP---LAGKAICRPCHSLCKKCNG--YGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPE 672 GKICIGT GR+SVP+N++HHYRNLRDRYTNCTYVDGNLE+TWLQ+E DLSFLQ+IREVTGYVLISHVDV+KIVLP LQIIRGRTLFKL++ D +F+L VT+ +M L +L DIL GSVG+ NNYNLCHI+TI WEEIITGP Y YVYNF PER CTPC +SC+ GCWGEGP NCQK+SK NCSPQC +GRCFG PRECCHLFCAGGCTGPKQSDC+AC+NFFDDGV ECPPMQ+YNP Y WE NP+GKYAYGATCV+ CP+HLLKDNGACVR CPPKKK +NGECVPCDGPCPKTC E +H+GNIDSF++CT+IEGSITILD +F GFQ Y N++FG RY M P KLEVF+TLKE+TG++NIQG H +FKNL+ FRNLEVIGGRTLTEYF++LY+VKT+L S GL SL+KI SG+++ILENK+LCYAQ INW +I KS H +LL NN+N ECI+ +CD QCS EGCWGPG CLSCK F Q P A + C+ CH ++C+G G + D C++C H CVPEC Y D+ CK C C GC G +GP+ C +C K L PE Sbjct: 43 GKICIGTNGRLSVPSNKQHHYRNLRDRYTNCTYVDGNLEITWLQNETFDLSFLQYIREVTGYVLISHVDVKKIVLPRLQIIRGRTLFKLTIHDIEFALFVTMCQMQNLSRVSLPDILNGSVGMYNNYNLCHIRTINWEEIITGPSAMYSYVYNFTSPERACTPCDKSCEQGCWGEGPENCQKYSKTNCSPQCWQGRCFGPNPRECCHLFCAGGCTGPKQSDCIACKNFFDDGVCTQECPPMQKYNPTTYSWEPNPDGKYAYGATCVRRCPEHLLKDNGACVRSCPPKKKALNGECVPCDGPCPKTCKGVEKVHSGNIDSFKDCTIIEGSITILDQSFQGFQHVYRNFSFGKRYEKMHPDKLEVFSTLKEITGFLNIQGDHKDFKNLSYFRNLEVIGGRTLTEYFASLYVVKTSLVSFGLSSLKKIYSGSIAILENKNLCYAQSINWTRIKKSSEHESLLSNNRNESECIKDGLVCDEQCSDEGCWGPGPAQCLSCKNFILGNDCLQDCTAPGIYQADEKTCKVCH---EECDGSCIGPNTDHCKKCKHARDGPFCVPECPASKYNDNGVCKSCHGNCVGGCEGPENNIGPNGCHSCD--KAILNDHVPE 646 HSP 2 Score: 122.865 bits (307), Expect = 2.450e-27 Identity = 52/89 (58.43%), Postives = 66/89 (74.16%), Query Frame = 0 Query: 579 QGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK-CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 QG L+PLA KA+CR CHS CKKC GYGFH+ VCQEC + + +QC EC DY+ D+ K C PC ECRGC+G GP++C C+NYK+Y+ Sbjct: 669 QGPLKPLASKAVCRKCHSRCKKCTGYGFHEHVCQECTKYKRGEQCEDECPADYFADANKLCIPCFSECRGCFGPGPNQCYKCRNYKIYI 757
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: gb|EFA01355.2| (torpedo [Tribolium castaneum]) HSP 1 Score: 800.816 bits (2067), Expect = 0.000e+0 Identity = 372/595 (62.52%), Postives = 453/595 (76.13%), Query Frame = 0 Query: 65 GIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLA-----------GKAICRPCHSLC-KKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRG 647 + HH GKICIGT GRMSVP+NREHHYRNL+DRYTNCTYVDGNLELTWLQDENLDLSFLQ+IREVTGYVLISHVD+++IVLP LQIIRGRTLFK++VR+++F+L+V LSKM+ LE+PALRD+L G+VG+ NNYNLCH KTI W+EIIT P+ KYV+VYNF PERDC PCH++C+ GCWGEG NCQKFSK NCSPQC++GRCFG PRECCHLFCAGGCTGPKQSDC+ACRNF+DDGV ECPPM+ Y+PI Y W+ NP GKYAYGATCVK CP+HLLKDNGACVR CPP KK G CVPC+GPCPKTC + +H+GNID+F+ CTVIEG+I IL +TF G+Q Y NYTFG RYP M P +LEVF+TLKEVTG+IN+Q +H +F NL+ FRNLEVIGGR+L++YF++LYIVK++L SL L+SL+++ +G V+ILEN LC+A INW KI +S H ++ NN +P+ C + +CD +CS +GCWG G + CLSC FQ + + +A G IC+ CH C C G G D C C F CVP C + Y ++ +CK C C G Sbjct: 39 ALALHHQENEFHNKGKICIGTNGRMSVPSNREHHYRNLKDRYTNCTYVDGNLELTWLQDENLDLSFLQYIREVTGYVLISHVDIKRIVLPRLQIIRGRTLFKMNVRNEEFALLVILSKMYTLELPALRDVLIGNVGVFNNYNLCHFKTINWKEIITDPKSKYVFVYNFTSPERDCPPCHKNCEKGCWGEGEENCQKFSKENCSPQCYQGRCFGPNPRECCHLFCAGGCTGPKQSDCIACRNFYDDGVCTQECPPMKIYSPITYSWQDNPNGKYAYGATCVKNCPEHLLKDNGACVRSCPPDKKAHEGACVPCNGPCPKTCRVDTFIHSGNIDTFKGCTVIEGNILILQNTFEGYQHFYPNYTFGARYPRMHPDRLEVFSTLKEVTGHINVQAYHSDFTNLSYFRNLEVIGGRSLSDYFTSLYIVKSSLKSLELRSLKRLNAGTVAILENTHLCFADNINWDKIRRSHEHVVMISNNSDPRLCKGNNLVCDSECSRDGCWGAGPDQCLSCAHFQLENESRCIANCSVLPGIYQDGPNICKRCHEECGSSCTGPG--ADKCVTCKRFQDGPYCVPSCPTNKYHENGQCKSCHANCVG 631 HSP 2 Score: 107.457 bits (267), Expect = 1.112e-22 Identity = 48/99 (48.48%), Postives = 68/99 (68.69%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPEC-DGDYYKDSTK-CKPCSEECRGCYGMGPDKCLACKNYKVYLTGEFPED 673 Q + L+ LAG A+CR CH CK C+G+GFH+ VCQ+C H+ +D+QC EC GDY + + CKPC EC+GC G GP+ C++C+N+KV+ G E+ Sbjct: 681 QEKESLKSLAGSALCRKCHPRCKICSGFGFHELVCQKCTHYKKDEQCEDECRSGDYADEEVQECKPCDPECKGCTGPGPENCISCENFKVFDDGYVSEN 779
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: gb|EEC14327.1| (epidermal growth factor receptor, putative, partial [Ixodes scapularis]) HSP 1 Score: 774.237 bits (1998), Expect = 0.000e+0 Identity = 368/578 (63.67%), Postives = 445/578 (76.99%), Query Frame = 0 Query: 81 ICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSG-CWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK-LEPLA--------GKAICRPCHSLC-KKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRG 647 +CIGT GRMSVP+NREHHY+NLRDRYTNCTYVDGNLELTWLQ+++LDLSFL+ IREVTGYVLISHVDV++I+LPSL I+RGR LFKL+V D++F+L+VTLSKM LE+PALRDIL G+VG NNYNLCH++ ++W+EI++GP VYVYNF +PER C PC SC+ G CWGEGP NCQKFSK+NCSPQCH+GRCFG PRECCHLFCAGGC GPKQSDCLAC+NF+DDGV K ECPPM RYNP Y WE NP+GKYAYGATCV++CP+HLL+D+GACVR CPP KK +GECVPCDGPCPK C ++++ NI+ F+ CT+IEGS+TILDSTF +FG RY MDP KLEVF+TLKEVTGY+NIQ HPNF +L+ FRNLEVIGGRTLTEYF+ALYIVK++L SL L+SL KIRSG+V+ILENKDLC+A ++W ++MKS +HN LLQ N N +C Q+ +C QCS GCWGP N CLSCK ++ + +E G +C+ CH C +C G G ++ C +C H CV EC Y S +C PC E C G Sbjct: 4 VCIGTNGRMSVPSNREHHYQNLRDRYTNCTYVDGNLELTWLQNKSLDLSFLRDIREVTGYVLISHVDVQRILLPSLMIVRGRNLFKLNVHDEEFALIVTLSKMDNLELPALRDILRGNVGFFNNYNLCHVRGVQWDEILSGPPAHMVYVYNFTQPERTCPPCDASCRGGHCWGEGPHNCQKFSKVNCSPQCHQGRCFGPEPRECCHLFCAGGCVGPKQSDCLACQNFYDDGVCKQECPPMMRYNPNTYSWEDNPDGKYAYGATCVRDCPEHLLRDSGACVRNCPPNKKAQHGECVPCDGPCPKNCQGVNIVNSINIELFRGCTIIEGSLTILDSTF----------SFGPRYEEMDPSKLEVFSTLKEVTGYVNIQASHPNFTSLSYFRNLEVIGGRTLTEYFAALYIVKSSLKSLNLRSLNKIRSGSVAILENKDLCFADSVDWYQVMKSSAHNILLQRNANRTDCEAQNLVCHSQCSTSGCWGPAPNECLSCKSYRLEDTCIEKCDTSKGIYDNGNYVCKHCHEECLGECYGPGANN--CTQCRHVRDGPYCVRECPDTKYNQSGECMPCHENCIG 569
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: EEB19606.1 (Epidermal growth factor receptor precursor, putative [Pediculus humanus corporis]) HSP 1 Score: 768.844 bits (1984), Expect = 0.000e+0 Identity = 370/589 (62.82%), Postives = 441/589 (74.87%), Query Frame = 0 Query: 89 MSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNE---VMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQG---------KLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEEC-RGCYG----MGPDKCLACK 660 MSVP+NREHHYRNLR+RYTNC+YVDGNLELTW++DENLDLSFLQ+IREVTGYVL+SHV V+++VLP LQIIRGRTLFKLS+ +F+LM++L KMH +EMPALRDIL G VG+ NNYNLCHI+TI W+EIITGP V+VYNF PER C C SC GCWGEGP NCQKFSK+NCSPQC +GRCFG PRECCHLFCAGGCTGPKQ+DCLACRNF+DDG ECP MQ YNP Y WE NP GKYAYGATCVK CP+HLLKDNGACVR CPP K NGECV C+G CPKTC E +HAGNID+F+ CT+I+GSI+ILD +F GFQ+ Y NY+FG RYP M P +LEVF+TLKEVTG+INIQG H +F+NL+ FRNLE+IGGRTLTEYF ALYIVKT+LTSLGL+SL+KI SG++ ILENK+LC+A +NW I KS H L+ N+N +C+++ +CDPQCS+EGCWGPG C+SC F+ K AG +C+PCH C +G + C +C H C C Y D+ +CK C C GC G +GP+ C +C+ Sbjct: 1 MSVPSNREHHYRNLRERYTNCSYVDGNLELTWIEDENLDLSFLQNIREVTGYVLVSHVYVKRVVLPKLQIIRGRTLFKLSIHQQEFALMISLCKMHTIEMPALRDILAGGVGLFNNYNLCHIRTINWKEIITGPGYHDVFVYNFTSPERKCKSCDPSCPKGCWGEGPENCQKFSKLNCSPQCSEGRCFGPNPRECCHLFCAGGCTGPKQTDCLACRNFYDDGECTQECPSMQTYNPSTYSWENNPRGKYAYGATCVKNCPEHLLKDNGACVRSCPPNKTPYNGECVNCEGACPKTCKGVESDGSVHAGNIDNFKGCTIIDGSISILDHSFKGFQQIYTNYSFGPRYPEMHPDRLEVFSTLKEVTGFINIQGSHEDFRNLSYFRNLEIIGGRTLTEYF-ALYIVKTSLTSLGLQSLKKISSGSIGILENKELCFADGVNWTNIKKSIGHKVLILQNRNESDCVKKGLVCDPQCSSEGCWGPGPKQCISCINFKNGNECVQDCNSIKGMYTAGPNLCKPCHEECAS-TCFGPGNGNCTKCKHVRDGPFCYSSCPETKYNDNGECKSCHPNCVNGCTGPENTIGPNGCASCE 587 HSP 2 Score: 110.153 bits (274), Expect = 1.741e-23 Identity = 62/159 (38.99%), Postives = 77/159 (48.43%), Query Frame = 0 Query: 553 CDPQCSAEGCWGPGN----NSCLSCKKF-----------------------------QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDST--KCKPCSEECRGCYGMGPDKCLACKNYKVYLTGEFPEDDNV 676 C P C GC GP N N C SC+K Q QG + LAGK ICR CH CKKC GYG H+ VCQEC ++ + Q C EC D+Y + T +C PCS ECR CYG C C+N+++YL P D++ Sbjct: 563 CHPNC-VNGCTGPENTIGPNGCASCEKAIINADLTVESCLPKDEPCPIGYYYEWVGPQFQGPFKELAGKGICRKCHPTCKKCTGYGIHEQVCQECTNYKRGQHCEDECPQDHYVNETTQECSPCSPECRDCYGPKSTHCFKCRNFRIYLDENGPRDNDT 720 HSP 3 Score: 88.9669 bits (219), Expect = 5.563e-17 Identity = 100/361 (27.70%), Postives = 149/361 (41.27%), Query Frame = 0 Query: 74 NSQPHGKICIGTKGR-----MSVPNNREHHYRNLRDRYTNCTYVDGNLEL-----TWLQDENLDLSF--------------LQHIREVTGYVLI--SHVDVRKI-VLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTP----CHESCQS-GCWGEGPSNCQKFSKIN------CSPQCHKGR-CFGELPREC--CHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKEC--PKHLLKDNG--ACVRICPPKKKTVNGECVPCDGPCPKTCHFNEV 389 N P+ C+ +G V ++ H N+ D + CT +DG++ + Q + SF ++EVTG++ I SH D R + +L+II GRTL + F+L + + + L + +L+ I GS+GIL N LC + W I K + + N NE DC C C S GCWG GP C S IN C C+ + + P C CH CA C GP +C C++ D CP + ++ N E K + CV C P++ + NG +C + TV C+P D PCP ++ V Sbjct: 277 NKTPYNGECVNCEGACPKTCKGVESDGSVHAGNI-DNFKGCTIIDGSISILDHSFKGFQQIYTNYSFGPRYPEMHPDRLEVFSTLKEVTGFINIQGSHEDFRNLSYFRNLEIIGGRTL------TEYFALYIVKTSLTSLGLQSLKKISSGSIGILENKELCFADGVNWTNIKKSIGHKVLILQNRNE--SDCVKKGLVCDPQCSSEGCWGPGPKQC--ISCINFKNGNECVQDCNSIKGMYTAGPNLCKPCHEECASTCFGPGNGNCTKCKHVRDGPFCYSSCP--------ETKYNDNGECKSCH-PNCVNGCTGPENTIGPNGCASCEKAIINADLTVES-CLPKDEPCPIGYYYEWV 616
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: AAF46732.1 (epidermal growth factor receptor, isoform B [Drosophila melanogaster]) HSP 1 Score: 749.199 bits (1933), Expect = 0.000e+0 Identity = 357/595 (60.00%), Postives = 426/595 (71.60%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTE-YFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLAG---------KAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRGCYG----MGPDKCLAC 659 GKICIGTK R+SVP+N+EHHYRNLRDRYTNCTYVDGNLELTWL +ENLDLSFL +IREVTGY+LISHVDV+K+V P LQIIRGRTLF LSV ++K++L VT SKM+ LE+P LRD+L G VG NNYNLCH++TI+W EI++ Y Y Y+F PER+C CHESC GCWGEGP NCQKFSK+ CSPQC GRC+G PRECCHLFCAGGCTGP Q DC+AC+NFFD+GV K ECPPM++YNP Y E NPEGKYAYGATCVKECP HLL+DNGACVR CP K GECVPC+GPCPKTC V+HAGNIDSF+NCTVI+G+I ILD TF+GFQ+ Y NYT G RY +DP++LEVF+T+KE+TGY+NI+G HP F+NL+ FRNLE I GR L E F+AL IVK++L SL +++L++I SG+V I N+DLCY I W I K P + N C + +C QC+ +GCWG G + CL+CK F G G C+ CH C+ CNG G D CQECVH Q CV EC + Y D C+ C C GC G +G C C Sbjct: 99 GKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLELTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVTYSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAY-YNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEGVCKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGECVPCNGPCPKTCPGVTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERLEVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYISNAYKFDNRTCKICHPECRTCNGAG--ADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTC 690 HSP 2 Score: 102.449 bits (254), Expect = 4.103e-21 Identity = 44/95 (46.32%), Postives = 61/95 (64.21%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYLTGE 669 Q QG L+PLAG+A+CR CH LC+ C YG+H+ VC +C H+ + +QC EC D+Y D + C C EC GC G G D C +C+N+K++ E Sbjct: 723 QEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQCHPECNGCTGPGADDCKSCRNFKLFDANE 817
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: AAM70919.1 (epidermal growth factor receptor, isoform A [Drosophila melanogaster]) HSP 1 Score: 748.814 bits (1932), Expect = 0.000e+0 Identity = 363/632 (57.44%), Postives = 440/632 (69.62%), Query Frame = 0 Query: 42 ILLLLLCIVLWKNPSPVEASSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTE-YFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLAG---------KAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRGCYG----MGPDKCLAC 659 +LL+L C+ S V S+ G + + + K+CIGTK R+SVP+N+EHHYRNLRDRYTNCTYVDGNLELTWL +ENLDLSFL +IREVTGY+LISHVDV+K+V P LQIIRGRTLF LSV ++K++L VT SKM+ LE+P LRD+L G VG NNYNLCH++TI+W EI++ Y Y Y+F PER+C CHESC GCWGEGP NCQKFSK+ CSPQC GRC+G PRECCHLFCAGGCTGP Q DC+AC+NFFD+GV K ECPPM++YNP Y E NPEGKYAYGATCVKECP HLL+DNGACVR CP K GECVPC+GPCPKTC V+HAGNIDSF+NCTVI+G+I ILD TF+GFQ+ Y NYT G RY +DP++LEVF+T+KE+TGY+NI+G HP F+NL+ FRNLE I GR L E F+AL IVK++L SL +++L++I SG+V I N+DLCY I W I K P + N C + +C QC+ +GCWG G + CL+CK F G G C+ CH C+ CNG G D CQECVH Q CV EC + Y D C+ C C GC G +G C C Sbjct: 23 VLLILACMASITTSSSV--SNAGYVDNGNM--------KVCIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLELTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVTYSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAY-YNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEGVCKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGECVPCNGPCPKTCPGVTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERLEVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYISNAYKFDNRTCKICHPECRTCNGAGA--DHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTC 641 HSP 2 Score: 102.449 bits (254), Expect = 3.646e-21 Identity = 44/95 (46.32%), Postives = 61/95 (64.21%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYLTGE 669 Q QG L+PLAG+A+CR CH LC+ C YG+H+ VC +C H+ + +QC EC D+Y D + C C EC GC G G D C +C+N+K++ E Sbjct: 674 QEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQCHPECNGCTGPGADDCKSCRNFKLFDANE 768
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: EAA10104.4 (AGAP008819-PA, partial [Anopheles gambiae str. PEST]) HSP 1 Score: 729.169 bits (1881), Expect = 0.000e+0 Identity = 344/593 (58.01%), Postives = 432/593 (72.85%), Query Frame = 0 Query: 82 CIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTE-YFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK----------LEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECRGCYG----MGPDKCLAC 659 CIGT GRMSVP NRE+HY+NLRDRYTNCTYVDGNLE+TW+Q+ DL+FLQHIREVTGYVLISH+D+ +++LP LQIIRGRT FKL+ ++ + L V+ S M+ LE+PALRDIL GSVG NNYNLCH+K+I WEEI++ P+ Y +NF+ PER C PCH SC+ GCWGEG NCQ+FSK+NCSPQC +GRCFG PRECCHLFCAGGCTGP QSDCLAC+NF+DDGV K ECPPMQ YNP Y WE NP+GKYAYGATCV++CP+HLLKDNGACVR CP K N ECVPC G CPKTC ++H+ NI ++++CT+IEGS+ ILD +F+GFQ+ Y N++FG RY +DP +LEVF+T+KE+TG+INIQ HHPNF LN FRNLEV+GGR L E F+++YIVKT+L SL LKSL+++ SG++ ILEN DLC+ ++I+W +I KS H ++Q N+N EC + C QCS GCWG G CL CK + +GK L + K C CH CK YG ++D C C++ + CV EC + + C C + C GC G + PD C++C Sbjct: 1 CIGTNGRMSVPANREYHYKNLRDRYTNCTYVDGNLEITWIQNIT-DLNFLQHIREVTGYVLISHIDLPQVILPRLQIIRGRTTFKLNKWEEAYGLFVSFSHMNTLELPALRDILGGSVGFFNNYNLCHMKSINWEEILSAPQTSMQYTFNFSSPERVCPPCHPSCEVGCWGEGAHNCQRFSKLNCSPQCSQGRCFGPKPRECCHLFCAGGCTGPTQSDCLACKNFYDDGVCKQECPPMQIYNPTNYFWEPNPDGKYAYGATCVRKCPEHLLKDNGACVRKCPKGKMPQNSECVPCKGVCPKTCPGEGIVHSDNIGNYKDCTIIEGSLEILDQSFDGFQQVYTNFSFGPRYIKIDPDRLEVFSTVKEITGFINIQAHHPNFTTLNYFRNLEVVGGRQLKENLFASVYIVKTSLKSLELKSLKRVNSGSIVILENSDLCFVEDIDWSEIKKSSDHEVMVQKNRNATECHEEGMECSEQCSKAGCWGKGPEQCLECKNVKYKGKCLDSCKSLPRLYSVDSKT-CGDCHQECKD-FCYGPNEDNCGSCMNVKDGRFCVAECPTTKHAMNGTCINCHKTCVGCRGPRDTIAPDGCISC 590 HSP 2 Score: 106.301 bits (264), Expect = 2.403e-22 Identity = 45/92 (48.91%), Postives = 63/92 (68.48%), Query Frame = 0 Query: 576 FQTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYY--KDSTKCKPCSEECRGCYGMGPDKCLACKNYKVY 665 Q +G L+ L+GKA+CR CH CKKC GYGFH+ CQEC + + +QC EC D+Y +++ C PC +ECRGC+G+G D C C+N K++ Sbjct: 621 LQEEGPLKQLSGKAVCRKCHPRCKKCTGYGFHEQFCQECTGYKKGEQCEDECPQDFYANEETRICLPCHQECRGCHGLGDDHCDECRNLKLF 712
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: gb|KFM81599.1| (Epidermal growth factor receptor, partial [Stegodyphus mimosarum]) HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0 Identity = 316/515 (61.36%), Postives = 379/515 (73.59%), Query Frame = 0 Query: 158 IIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDC---TPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQ----GKLEPL-----AGKAICRPCHSLC-KKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPD 654 IIRGR LFKL+VRD+ F+LMVTLS + LE+P+LRDIL GSVG NYNLCH++TI+W+EI+TGP K VYVYNF PER C + C ESC++GCWGEGP NCQ FSKINCSPQCH+GRCFG PRECCHLFCAGGCTGP Q+DCLACRNF+D+GV K ECPPM RYNP Y WE NP GKYAYGATCVK CP HLL+D+GACVR CP KK N ECVPCDGPCPK C +V+HA NIDSF+ CT+IEGSITILD++F+G+QE Y+N+TFG +YP M P +LE F++LKEVTGY++IQ HP FKNL+ FRNLE+IGGR LTEYF+ALYIVKT+L SLG++SL+KI SG+++ILEN DLC+A INW+KI KS SH+ LLQ+N N C ++ C PQCS +GCWGP N CLSCK + K + L AG +C+ CH C C G G + C C + CV +C Y+D CK C C GCYG +GP+ Sbjct: 2 IIRGRNLFKLNVRDEDFALMVTLSNIFNLELPSLRDILTGSVGFYYNYNLCHVRTIKWDEILTGPDAKPVYVYNFTYPERHCEFKSTCDESCEAGCWGEGPHNCQNFSKINCSPQCHQGRCFGPNPRECCHLFCAGGCTGPTQADCLACRNFYDNGVCKQECPPMMRYNPASYSWESNPNGKYAYGATCVKNCPDHLLRDSGACVRTCPANKKAENHECVPCDGPCPKNCQGVDVVHANNIDSFKGCTIIEGSITILDTSFDGYQEVYQNFTFGPKYPRMHPSRLEAFSSLKEVTGYVSIQALHPEFKNLSCFRNLEIIGGRQLTEYFAALYIVKTSLESLGMRSLKKISSGSIAILENDDLCFANTINWKKIRKSGSHSILLQSNGNETICQARNLKCHPQCSTDGCWGPAPNECLSCKAYNLNDTCVAKCDTLNGMYDAGNKVCKYCHEECLGLCFGPG--NGNCSACRNVRDGPYCVSKCPETKYRDGGICKQCHGNCAGGCYGPENNIGPN 514
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: gb|KFM71324.1| (Epidermal growth factor receptor, partial [Stegodyphus mimosarum]) HSP 1 Score: 604.749 bits (1558), Expect = 0.000e+0 Identity = 285/423 (67.38%), Postives = 337/423 (79.67%), Query Frame = 0 Query: 61 SSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPE---RDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTE 480 S LG HH + GKICIGT GRMSVP NR+HHY+NLRDRYTNCT+VDGNLE+TWLQDE+ DLSFL+ IREVTGYVLISHV++R+IVLP L IIRGR LF L D F+L+V + + LE+PALRDIL G VG +N LC+I TI WEEI+T K ++YN E + C PCH+SC++GCWG GP +CQKFSKINCSPQCH+GRCFG PRECCHLFCAGGC+GP QSDCLAC+NF D+GV K ECPPM+RYNP+ Y WE NPEGKYAYGATCVK CP+HLL+D+GACVR CP K+ V+GECVPCDGPCPK+C +H+GNID F+ CTVIEGS+TILDSTF+GFQE + N+TFG+R+P M P +LEVF+TLKEVTGY+NIQ HP+FKNL+ FRNLE+I GR LTE Sbjct: 18 SQLGTAAVHH-KDTYVMKGKICIGTSGRMSVPANRDHHYQNLRDRYTNCTHVDGNLEITWLQDESQDLSFLKEIREVTGYVLISHVNIRRIVLPKLMIIRGRNLFDLQPGD--FALLVAHTNLGILELPALRDILAGEVGFFDNDELCYIDTINWEEILTRNHMKLPFIYNSTRQEGSAKRCPPCHKSCEAGCWGPGPHSCQKFSKINCSPQCHQGRCFGPNPRECCHLFCAGGCSGPTQSDCLACKNFDDNGVCKQECPPMRRYNPVTYSWESNPEGKYAYGATCVKNCPEHLLRDSGACVRSCPETKRAVDGECVPCDGPCPKSCTGVTALHSGNIDRFRGCTVIEGSLTILDSTFDGFQEVFPNFTFGDRFPKMHPDELEVFSTLKEVTGYLNIQASHPDFKNLSYFRNLEIIDGRQLTE 437 HSP 2 Score: 74.3294 bits (181), Expect = 5.905e-13 Identity = 73/254 (28.74%), Postives = 113/254 (44.49%), Query Frame = 0 Query: 387 NEVMHAGNI-DSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFS---ALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL--LQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGKLEPLAGKAIC------RPCHSLCK-KCNGYGFHDDVCQECVHFSQDQQCVPEC 627 N H N+ D + NCT ++G++ I Q+ ++ +F ++EVTGY+ I H N + + L +I GR L + AL + T L L L +LR I +G V +N +LCY INW++I+ + +H L + N+ + ++ C C A GCWGPG + SC+KF ++ P + C CH C C+G D C C +F + C EC Sbjct: 50 NRDHHYQNLRDRYTNCTHVDGNLEI-----TWLQDESQDLSF--------------LKEIREVTGYVLIS--HVNIRRI-VLPKLMIIRGRNLFDLQPGDFALLVAHTNLGILELPALRDILAGEVGFFDNDELCYIDTINWEEIL-TRNHMKLPFIYNSTRQEGSAKRCPPCHKSCEA-GCWGPGPH---SCQKF-SKINCSPQCHQGRCFGPNPRECCHLFCAGGCSGPTQSD--CLACKNFDDNGVCKQEC 273
BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Match: EFX77630.1 (hypothetical protein DAPPUDRAFT_53919, partial [Daphnia pulex]) HSP 1 Score: 536.954 bits (1382), Expect = 0.000e+0 Identity = 250/359 (69.64%), Postives = 288/359 (80.22%), Query Frame = 0 Query: 82 CIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVR-DDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVR-ICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKK 438 C+GT RMSVP+NR HY NLRD YTNCTYVDGNLELTWLQ+E+LDL+FLQHIREVTGYVLISHV++R+ VLP+LQIIRGRTLFK + D+ F+L+V LSKMH LE PALRDIL GS G+ NNYNLCH+KTI WEEIITG K VYNF EPERDC PCH+SC+ GCWGEG NCQKFSKINCS +C++GRCFG ECCH FC GGCTGPK SDCLACRNF D+GV K +CP QRYNPI + WE NPE KY YG++CVK CP++ L+++ CVR ICPPKK V+GECV CDGPCPKTC E +HAGNI+SF+NCTVIEGS+ I+D +F GFQ Y N+TFG YP M P K Sbjct: 1 CVGTSSRMSVPSNRSAHYLNLRDNYTNCTYVDGNLELTWLQEESLDLTFLQHIREVTGYVLISHVEIRRFVLPALQIIRGRTLFKYNTHGDEGFALIVILSKMHSLETPALRDILAGSCGMFNNYNLCHVKTINWEEIITGSGSKLFNVYNFTEPERDCQPCHKSCEGGCWGEGAENCQKFSKINCSSECNQGRCFGPKSSECCHSFCIGGCTGPKPSDCLACRNFSDNGVCKQKCPATQRYNPITHSWETNPEAKYEYGSSCVKTCPENFLREDDTCVRVICPPKKMAVDGECVICDGPCPKTCKGVEFVHAGNIESFRNCTVIEGSLAIIDHSFTGFQHIYPNFTFGPAYPRMHPTK 359 HSP 2 Score: 72.7886 bits (177), Expect = 1.341e-12 Identity = 71/254 (27.95%), Postives = 110/254 (43.31%), Query Frame = 0 Query: 387 NEVMHAGNI-DSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFS------ALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSC-----LSCKKFQTQGKLEPLAGKAICRPCHSLC-KKCNGYGFHDDVCQECVHFSQDQQCVPEC 627 N H N+ D++ NCT ++G++ + QE + TF ++EVTGY+ I H + L++I GRTL +Y + AL ++ + + SL +LR I +G+ + N +LC+ + INW++I+ + L N N E R C C GCWG G +C ++C QG+ G CHS C C G D C C +FS + C +C Sbjct: 13 NRSAHYLNLRDNYTNCTYVDGNLEL-----TWLQEESLDLTF--------------LQHIREVTGYVLIS--HVEIRRF-VLPALQIIRGRTLFKYNTHGDEGFALIVILSKMHSLETPALRDILAGSCGMFNNYNLCHVKTINWEEIITGSG--SKLFNVYNFTEPERDCQPCHKSCEG-GCWGEGAENCQKFSKINCSSECNQGR---CFGPKSSECCHSFCIGGCTGPKPSD--CLACRNFSDNGVCKQKC 236
BLAST of EMLSAG00000007374 vs. nr
Match: gi|942311143|gb|JAN37504.1| (Receptor tyrosine-protein kinase erbB-3 [Daphnia magna]) HSP 1 Score: 848.581 bits (2191), Expect = 0.000e+0 Identity = 416/636 (65.41%), Postives = 482/636 (75.79%), Query Frame = 0 Query: 54 NPSPVEASSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK----------LEPLAGKAICRPCHSLCKK-CNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPED 673 NPSP + + N GKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDE+LDL+FLQHIREVTGYVLISHVDV++IVLP+LQIIRGRTLFKLSV D++F+L+VTLSKMH LEMPALRDIL GS G+ NNYNLCH+KTI WEEIITG K + VYNF EPER+C CHESC++GCWGEGP NCQKFSKINCSPQCH+GRCFG PRECCHLFCAGGCTGPKQSDCLACRNFFDDGV ECP MQRYNPI Y WE NPEGKYAYGATCVK CP+HLLKDNGACVRICP KKK VNGECV CDGPCPKTC +++HAGNI+SF++CTVIEGSI+ILD +F GFQ+ Y N+TFG RYP + P +LE+F+TL+E+TG+IN+Q HP+FKNL+ FRNLE IGGR LTEYFSALYIVKT+L SL L+SL+ IR+G+V+ILENK+LC+A+ I+W KI+KS H TLLQNNK Q+C +C QCS EGCWG G N CLSC FQ + L K +C+ CH C + C G G + C C H CVP C + DS +C C + C GC G +GP C +C+ K + G+ D Sbjct: 41 NPSPADKA------------NDVFKGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDEHLDLTFLQHIREVTGYVLISHVDVKRIVLPALQIIRGRTLFKLSVHDEEFALVVTLSKMHNLEMPALRDILAGSCGLFNNYNLCHMKTINWEEIITGTGSKIINVYNFTEPERECPACHESCEAGCWGEGPENCQKFSKINCSPQCHQGRCFGPRPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVCNQECPAMQRYNPITYSWETNPEGKYAYGATCVKTCPEHLLKDNGACVRICPAKKKAVNGECVVCDGPCPKTCQGVDIVHAGNIESFRDCTVIEGSISILDHSFGGFQQIYPNFTFGPRYPRLHPDRLEIFSTLQEITGFINVQASHPDFKNLSYFRNLETIGGRQLTEYFSALYIVKTSLNSLHLRSLKMIRAGSVTILENKELCFAESISWTKIIKSQLHGTLLQNNKVSQQCQESGLVCSAQCSVEGCWGLGPNECLSCAHFQLDETCVESCDLNLGIYELTPK-LCKHCHHECDETCTGPGPGN--CTVCKHVKDGPYCVPACPTSKFNDSGECVSCHDNCVGGCTGPENNIGPRGCHSCE--KAVINGDVEVD 659 HSP 2 Score: 113.62 bits (283), Expect = 7.899e-22 Identity = 50/92 (54.35%), Postives = 65/92 (70.65%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 Q QG L+PLAGKA+CR CH CK+C GYGFH+ VCQECV + + +QC EC D+Y D + C C+ ECRGC G ++C +C+NY+VYL Sbjct: 680 QEQGPLKPLAGKAVCRKCHPRCKRCIGYGFHEQVCQECVKYKRGEQCEDECPQDHYADEERHECSRCASECRGCSGPNVNQCQSCRNYRVYL 771
BLAST of EMLSAG00000007374 vs. nr
Match: gi|942306141|gb|JAN35003.1| (Receptor tyrosine-protein kinase erbB-3 [Daphnia magna]) HSP 1 Score: 848.195 bits (2190), Expect = 0.000e+0 Identity = 411/611 (67.27%), Postives = 475/611 (77.74%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK----------LEPLAGKAICRPCHSLCKK-CNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPED 673 GKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDE+LDL+FLQHIREVTGYVLISHVDV++IVLP+LQIIRGRTLFKLSV D++F+L+VTLSKMH LEMPALRDIL GS G+ NNYNLCH+KTI WEEIITG K + VYNF EPER+C CHESC++GCWGEGP NCQKFSKINCSPQCH+GRCFG PRECCHLFCAGGCTGPKQSDCLACRNFFDDGV ECP MQRYNPI Y WE NPEGKYAYGATCVK CP+HLLKDNGACVRICP KKK VNGECV CDGPCPKTC +++HAGNI+SF++CTVIEGSI+ILD +F GFQ+ Y N+TFG RYP + P +LE+F+TL+E+TG+IN+Q HP+FKNL+ FRNLE IGGR LTEYFSALYIVKT+L SL L+SL+ IR+G+V+ILENK+LC+A+ I+W KI+KS H TLLQNNK Q+C +C QCS EGCWG G N CLSC FQ + L K +C+ CH C + C G G + C C H CVP C + DS +C C + C GC G +GP C +C+ K + G+ D Sbjct: 54 GKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDEHLDLTFLQHIREVTGYVLISHVDVKRIVLPALQIIRGRTLFKLSVHDEEFALVVTLSKMHNLEMPALRDILAGSCGLFNNYNLCHMKTINWEEIITGTGSKIINVYNFTEPERECPACHESCEAGCWGEGPENCQKFSKINCSPQCHQGRCFGPRPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVCNQECPAMQRYNPITYSWETNPEGKYAYGATCVKTCPEHLLKDNGACVRICPAKKKAVNGECVVCDGPCPKTCQGVDIVHAGNIESFRDCTVIEGSISILDHSFGGFQQIYPNFTFGPRYPRLHPDRLEIFSTLQEITGFINVQASHPDFKNLSYFRNLETIGGRQLTEYFSALYIVKTSLNSLHLRSLKMIRAGSVTILENKELCFAESISWTKIIKSQLHGTLLQNNKVSQQCQESGLVCSAQCSVEGCWGLGPNECLSCAHFQLDETCVESCDLNLGIYELTPK-LCKHCHHECDETCTGPGPGN--CTVCKHVKDGPYCVPACPTSKFNDSGECVSCHDNCVGGCTGPENNIGPRGCHSCE--KAVINGDVEVD 659 HSP 2 Score: 113.62 bits (283), Expect = 7.967e-22 Identity = 50/92 (54.35%), Postives = 65/92 (70.65%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 Q QG L+PLAGKA+CR CH CK+C GYGFH+ VCQECV + + +QC EC D+Y D + C C+ ECRGC G ++C +C+NY+VYL Sbjct: 680 QEQGPLKPLAGKAVCRKCHPRCKRCIGYGFHEQVCQECVKYKRGEQCEDECPQDHYADEERHECSRCASECRGCSGPNVNQCQSCRNYRVYL 771
BLAST of EMLSAG00000007374 vs. nr
Match: gi|942302147|gb|JAN33006.1| (Receptor tyrosine-protein kinase erbB-3 [Daphnia magna]) HSP 1 Score: 848.195 bits (2190), Expect = 0.000e+0 Identity = 411/611 (67.27%), Postives = 475/611 (77.74%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK----------LEPLAGKAICRPCHSLCKK-CNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPED 673 GKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDE+LDL+FLQHIREVTGYVLISHVDV++IVLP+LQIIRGRTLFKLSV D++F+L+VTLSKMH LEMPALRDIL GS G+ NNYNLCH+KTI WEEIITG K + VYNF EPER+C CHESC++GCWGEGP NCQKFSKINCSPQCH+GRCFG PRECCHLFCAGGCTGPKQSDCLACRNFFDDGV ECP MQRYNPI Y WE NPEGKYAYGATCVK CP+HLLKDNGACVRICP KKK VNGECV CDGPCPKTC +++HAGNI+SF++CTVIEGSI+ILD +F GFQ+ Y N+TFG RYP + P +LE+F+TL+E+TG+IN+Q HP+FKNL+ FRNLE IGGR LTEYFSALYIVKT+L SL L+SL+ IR+G+V+ILENK+LC+A+ I+W KI+KS H TLLQNNK Q+C +C QCS EGCWG G N CLSC FQ + L K +C+ CH C + C G G + C C H CVP C + DS +C C + C GC G +GP C +C+ K + G+ D Sbjct: 54 GKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDEHLDLTFLQHIREVTGYVLISHVDVKRIVLPALQIIRGRTLFKLSVHDEEFALVVTLSKMHNLEMPALRDILAGSCGLFNNYNLCHMKTINWEEIITGTGSKIINVYNFTEPERECPACHESCEAGCWGEGPENCQKFSKINCSPQCHQGRCFGPRPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVCNQECPAMQRYNPITYSWETNPEGKYAYGATCVKTCPEHLLKDNGACVRICPAKKKAVNGECVVCDGPCPKTCQGVDIVHAGNIESFRDCTVIEGSISILDHSFGGFQQIYPNFTFGPRYPRLHPDRLEIFSTLQEITGFINVQASHPDFKNLSYFRNLETIGGRQLTEYFSALYIVKTSLNSLHLRSLKMIRAGSVTILENKELCFAESISWTKIIKSQLHGTLLQNNKVSQQCQESGLVCSAQCSVEGCWGLGPNECLSCAHFQLDETCVESCDLNLGIYELTPK-LCKHCHHECDETCTGPGPGN--CTVCKHVKDGPYCVPACPTSKFNDSGECVSCHDNCVGGCTGPENNIGPRGCHSCE--KAVINGDVEVD 659 HSP 2 Score: 113.62 bits (283), Expect = 8.314e-22 Identity = 50/92 (54.35%), Postives = 65/92 (70.65%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 Q QG L+PLAGKA+CR CH CK+C GYGFH+ VCQECV + + +QC EC D+Y D + C C+ ECRGC G ++C +C+NY+VYL Sbjct: 680 QEQGPLKPLAGKAVCRKCHPRCKRCIGYGFHEQVCQECVKYKRGEQCEDECPQDHYADEERHECSRCASECRGCSGPNVNQCQSCRNYRVYL 771
BLAST of EMLSAG00000007374 vs. nr
Match: gi|942324715|gb|JAN44290.1| (Receptor tyrosine-protein kinase erbB-3 [Daphnia magna]) HSP 1 Score: 847.81 bits (2189), Expect = 0.000e+0 Identity = 411/611 (67.27%), Postives = 475/611 (77.74%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK----------LEPLAGKAICRPCHSLCKK-CNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPED 673 GKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDE+LDL+FLQHIREVTGYVLISHVDV++IVLP+LQIIRGRTLFKLSV D++F+L+VTLSKMH LEMPALRDIL GS G+ NNYNLCH+KTI WEEIITG K + VYNF EPER+C CHESC++GCWGEGP NCQKFSKINCSPQCH+GRCFG PRECCHLFCAGGCTGPKQSDCLACRNFFDDGV ECP MQRYNPI Y WE NPEGKYAYGATCVK CP+HLLKDNGACVRICP KKK VNGECV CDGPCPKTC +++HAGNI+SF++CTVIEGSI+ILD +F GFQ+ Y N+TFG RYP + P +LE+F+TL+E+TG+IN+Q HP+FKNL+ FRNLE IGGR LTEYFSALYIVKT+L SL L+SL+ IR+G+V+ILENK+LC+A+ I+W KI+KS H TLLQNNK Q+C +C QCS EGCWG G N CLSC FQ + L K +C+ CH C + C G G + C C H CVP C + DS +C C + C GC G +GP C +C+ K + G+ D Sbjct: 54 GKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDEHLDLTFLQHIREVTGYVLISHVDVKRIVLPALQIIRGRTLFKLSVHDEEFALVVTLSKMHNLEMPALRDILAGSCGLFNNYNLCHMKTINWEEIITGTGSKIINVYNFTEPERECPACHESCEAGCWGEGPENCQKFSKINCSPQCHQGRCFGPRPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVCNQECPAMQRYNPITYSWETNPEGKYAYGATCVKTCPEHLLKDNGACVRICPAKKKAVNGECVVCDGPCPKTCQGVDIVHAGNIESFRDCTVIEGSISILDHSFGGFQQIYPNFTFGPRYPRLHPDRLEIFSTLQEITGFINVQASHPDFKNLSYFRNLETIGGRQLTEYFSALYIVKTSLNSLHLRSLKMIRAGSVTILENKELCFAESISWTKIIKSQLHGTLLQNNKVSQQCQESGLVCSAQCSVEGCWGLGPNECLSCAHFQLDETCVESCDLNLGIYELTPK-LCKHCHHECDETCTGPGPGN--CTVCKHVKDGPYCVPACPTSKFNDSGECVSCHDNCVGGCTGPENNIGPRGCHSCE--KAVINGDVEVD 659 HSP 2 Score: 113.62 bits (283), Expect = 7.821e-22 Identity = 50/92 (54.35%), Postives = 65/92 (70.65%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 Q QG L+PLAGKA+CR CH CK+C GYGFH+ VCQECV + + +QC EC D+Y D + C C+ ECRGC G ++C +C+NY+VYL Sbjct: 680 QEQGPLKPLAGKAVCRKCHPRCKRCIGYGFHEQVCQECVKYKRGEQCEDECPQDHYADEERHECSRCASECRGCSGPNVNQCQSCRNYRVYL 771
BLAST of EMLSAG00000007374 vs. nr
Match: gi|817211615|ref|XP_012281953.1| (PREDICTED: epidermal growth factor receptor isoform X1 [Orussus abietinus]) HSP 1 Score: 846.655 bits (2186), Expect = 0.000e+0 Identity = 404/608 (66.45%), Postives = 474/608 (77.96%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKF-------QTQGKLEPL--AGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPE 672 GKICIGT GR+SVP+N++HHYRNLRDRYTNCTYVDGNLE+TWLQ++ +DLSFLQ+IREVTGYVLISHVDVRKIVLP LQIIRGRTLFKL++ D +F+L VT+ +M+ LEMPALRDIL GSVG+ NNYNLCHIKTI W+EIITGP GKY YVYNF PER C C +SCQ GCWGEGP NCQ FSK NCSPQC +GRCFG PRECCHLFCAGGCTGPKQSDCLAC+NFFDDGV ECPPMQ+YNP Y WE NPEGKYAYGATCV++CP+HLLKDNGACVR CPPKKK VNGECVPCDGPCPKTC + +H+GNIDSF++CT+IEGSITILD +F GFQ + N+TFG+RY +M P +LEVF+TLKE+TG++NIQG H +F NL+ FRNLE+IGGRTLTEYF++LYIVKTAL SLGL SL+KI SG+++ILENKDLCYAQ I+W +I KS H +LL NNKN +CI++ +CD QCS EGCWGPG CLSCK F Q + + A IC+PCH C N G + + C +C H CVPEC Y D+ +C C E C GC G +G + C +C+ K + G PE Sbjct: 42 GKICIGTNGRLSVPSNKQHHYRNLRDRYTNCTYVDGNLEITWLQNDTVDLSFLQYIREVTGYVLISHVDVRKIVLPRLQIIRGRTLFKLNIHDVEFALFVTMCQMYNLEMPALRDILNGSVGVYNNYNLCHIKTINWDEIITGPGGKYTYVYNFTSPERACPECDKSCQQGCWGEGPENCQMFSKTNCSPQCWQGRCFGSNPRECCHLFCAGGCTGPKQSDCLACKNFFDDGVCTQECPPMQKYNPTTYSWEANPEGKYAYGATCVRKCPEHLLKDNGACVRSCPPKKKDVNGECVPCDGPCPKTCTGVDKVHSGNIDSFKDCTIIEGSITILDQSFEGFQHIFANFTFGSRYESMHPDRLEVFSTLKEITGFLNIQGDHKDFTNLSYFRNLEIIGGRTLTEYFASLYIVKTALVSLGLSSLKKISSGSIAILENKDLCYAQSIDWSRIKKSSEHESLLSNNKNESDCIKEGLVCDEQCSKEGCWGPGPAQCLSCKNFILGNVCIQDCNAIPGIYQADSRICKPCHEECDG-NCTGPNTEHCHKCKHVRDGPFCVPECPASKYNDNGQCTHCHENCVGGCEGPENNIGANGCHSCE--KAIMNGHVPE 646 HSP 2 Score: 113.62 bits (283), Expect = 8.556e-22 Identity = 47/96 (48.96%), Postives = 66/96 (68.75%), Query Frame = 0 Query: 576 FQTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYLTGE 669 Q QG L+PLAGKA+C+ CH CKKC G+G H+ VCQ C + + +QC EC D++ D+ C PC ECRGC+G GP++C +C+N+K+Y G+ Sbjct: 666 LQEQGALKPLAGKAVCKKCHPRCKKCTGFGIHEQVCQLCTKYKRGEQCEDECPADHFTDADTHLCIPCFGECRGCFGPGPNQCYSCRNFKIYTDGD 761
BLAST of EMLSAG00000007374 vs. nr
Match: gi|817211621|ref|XP_012281956.1| (PREDICTED: epidermal growth factor receptor isoform X4 [Orussus abietinus]) HSP 1 Score: 846.269 bits (2185), Expect = 0.000e+0 Identity = 404/608 (66.45%), Postives = 474/608 (77.96%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKF-------QTQGKLEPL--AGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPE 672 GKICIGT GR+SVP+N++HHYRNLRDRYTNCTYVDGNLE+TWLQ++ +DLSFLQ+IREVTGYVLISHVDVRKIVLP LQIIRGRTLFKL++ D +F+L VT+ +M+ LEMPALRDIL GSVG+ NNYNLCHIKTI W+EIITGP GKY YVYNF PER C C +SCQ GCWGEGP NCQ FSK NCSPQC +GRCFG PRECCHLFCAGGCTGPKQSDCLAC+NFFDDGV ECPPMQ+YNP Y WE NPEGKYAYGATCV++CP+HLLKDNGACVR CPPKKK VNGECVPCDGPCPKTC + +H+GNIDSF++CT+IEGSITILD +F GFQ + N+TFG+RY +M P +LEVF+TLKE+TG++NIQG H +F NL+ FRNLE+IGGRTLTEYF++LYIVKTAL SLGL SL+KI SG+++ILENKDLCYAQ I+W +I KS H +LL NNKN +CI++ +CD QCS EGCWGPG CLSCK F Q + + A IC+PCH C N G + + C +C H CVPEC Y D+ +C C E C GC G +G + C +C+ K + G PE Sbjct: 42 GKICIGTNGRLSVPSNKQHHYRNLRDRYTNCTYVDGNLEITWLQNDTVDLSFLQYIREVTGYVLISHVDVRKIVLPRLQIIRGRTLFKLNIHDVEFALFVTMCQMYNLEMPALRDILNGSVGVYNNYNLCHIKTINWDEIITGPGGKYTYVYNFTSPERACPECDKSCQQGCWGEGPENCQMFSKTNCSPQCWQGRCFGSNPRECCHLFCAGGCTGPKQSDCLACKNFFDDGVCTQECPPMQKYNPTTYSWEANPEGKYAYGATCVRKCPEHLLKDNGACVRSCPPKKKDVNGECVPCDGPCPKTCTGVDKVHSGNIDSFKDCTIIEGSITILDQSFEGFQHIFANFTFGSRYESMHPDRLEVFSTLKEITGFLNIQGDHKDFTNLSYFRNLEIIGGRTLTEYFASLYIVKTALVSLGLSSLKKISSGSIAILENKDLCYAQSIDWSRIKKSSEHESLLSNNKNESDCIKEGLVCDEQCSKEGCWGPGPAQCLSCKNFILGNVCIQDCNAIPGIYQADSRICKPCHEECDG-NCTGPNTEHCHKCKHVRDGPFCVPECPASKYNDNGQCTHCHENCVGGCEGPENNIGANGCHSCE--KAIMNGHVPE 646 HSP 2 Score: 113.235 bits (282), Expect = 9.385e-22 Identity = 47/96 (48.96%), Postives = 66/96 (68.75%), Query Frame = 0 Query: 576 FQTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYLTGE 669 Q QG L+PLAGKA+C+ CH CKKC G+G H+ VCQ C + + +QC EC D++ D+ C PC ECRGC+G GP++C +C+N+K+Y G+ Sbjct: 666 LQEQGALKPLAGKAVCKKCHPRCKKCTGFGIHEQVCQLCTKYKRGEQCEDECPADHFTDADTHLCIPCFGECRGCFGPGPNQCYSCRNFKIYTDGD 761
BLAST of EMLSAG00000007374 vs. nr
Match: gi|817211619|ref|XP_012281955.1| (PREDICTED: epidermal growth factor receptor isoform X3 [Orussus abietinus]) HSP 1 Score: 846.269 bits (2185), Expect = 0.000e+0 Identity = 404/608 (66.45%), Postives = 474/608 (77.96%), Query Frame = 0 Query: 79 GKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKF-------QTQGKLEPL--AGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPE 672 GKICIGT GR+SVP+N++HHYRNLRDRYTNCTYVDGNLE+TWLQ++ +DLSFLQ+IREVTGYVLISHVDVRKIVLP LQIIRGRTLFKL++ D +F+L VT+ +M+ LEMPALRDIL GSVG+ NNYNLCHIKTI W+EIITGP GKY YVYNF PER C C +SCQ GCWGEGP NCQ FSK NCSPQC +GRCFG PRECCHLFCAGGCTGPKQSDCLAC+NFFDDGV ECPPMQ+YNP Y WE NPEGKYAYGATCV++CP+HLLKDNGACVR CPPKKK VNGECVPCDGPCPKTC + +H+GNIDSF++CT+IEGSITILD +F GFQ + N+TFG+RY +M P +LEVF+TLKE+TG++NIQG H +F NL+ FRNLE+IGGRTLTEYF++LYIVKTAL SLGL SL+KI SG+++ILENKDLCYAQ I+W +I KS H +LL NNKN +CI++ +CD QCS EGCWGPG CLSCK F Q + + A IC+PCH C N G + + C +C H CVPEC Y D+ +C C E C GC G +G + C +C+ K + G PE Sbjct: 42 GKICIGTNGRLSVPSNKQHHYRNLRDRYTNCTYVDGNLEITWLQNDTVDLSFLQYIREVTGYVLISHVDVRKIVLPRLQIIRGRTLFKLNIHDVEFALFVTMCQMYNLEMPALRDILNGSVGVYNNYNLCHIKTINWDEIITGPGGKYTYVYNFTSPERACPECDKSCQQGCWGEGPENCQMFSKTNCSPQCWQGRCFGSNPRECCHLFCAGGCTGPKQSDCLACKNFFDDGVCTQECPPMQKYNPTTYSWEANPEGKYAYGATCVRKCPEHLLKDNGACVRSCPPKKKDVNGECVPCDGPCPKTCTGVDKVHSGNIDSFKDCTIIEGSITILDQSFEGFQHIFANFTFGSRYESMHPDRLEVFSTLKEITGFLNIQGDHKDFTNLSYFRNLEIIGGRTLTEYFASLYIVKTALVSLGLSSLKKISSGSIAILENKDLCYAQSIDWSRIKKSSEHESLLSNNKNESDCIKEGLVCDEQCSKEGCWGPGPAQCLSCKNFILGNVCIQDCNAIPGIYQADSRICKPCHEECDG-NCTGPNTEHCHKCKHVRDGPFCVPECPASKYNDNGQCTHCHENCVGGCEGPENNIGANGCHSCE--KAIMNGHVPE 646 HSP 2 Score: 113.235 bits (282), Expect = 9.336e-22 Identity = 47/96 (48.96%), Postives = 66/96 (68.75%), Query Frame = 0 Query: 576 FQTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYLTGE 669 Q QG L+PLAGKA+C+ CH CKKC G+G H+ VCQ C + + +QC EC D++ D+ C PC ECRGC+G GP++C +C+N+K+Y G+ Sbjct: 666 LQEQGALKPLAGKAVCKKCHPRCKKCTGFGIHEQVCQLCTKYKRGEQCEDECPADHFTDADTHLCIPCFGECRGCFGPGPNQCYSCRNFKIYTDGD 761
BLAST of EMLSAG00000007374 vs. nr
Match: gi|942343111|gb|JAN53488.1| (Receptor tyrosine-protein kinase erbB-3 [Daphnia magna]) HSP 1 Score: 845.884 bits (2184), Expect = 0.000e+0 Identity = 416/636 (65.41%), Postives = 482/636 (75.79%), Query Frame = 0 Query: 54 NPSPVEASSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK----------LEPLAGKAICRPCHSLCKK-CNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPED 673 NPSP + + N GKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDE+LDL+FLQHIREVTGYVLISHVDV++IVLP+LQIIRGRTLFKLSV D++F+L+VTLSKMH LEMPALRDIL GS G+ NNYNLCH+KTI WEEIITG K + VYNF EPER+C CHESC++GCWGEGP NCQKFSKINCSPQCH+GRCFG PRECCHLFCAGGCTGPKQSDCLACRNFFDDGV ECP MQRYNPI Y WE NPEGKYAYGATCVK CP+HLLKDNGACVRICP KKK VNGECV CDGPCPKTC +++HAGNI+SF++CTVIEGSI+ILD +F GFQ+ Y N+TFG RYP + P +LE+F+TL+E+TG+IN+Q HP+FKNL+ FRNLE IGGR LTEYFSALYIVKT+L SL L+SL+ IR+G+V+ILENK+LC+A+ I+W KI+KS H TLLQNNK Q+C +C QCS EGCWG G N CLSC FQ + L K +C+ CH C + C G G + C C H CVP C + DS +C C + C GC G +GP C +C+ K + G+ D Sbjct: 41 NPSPADKA------------NDVFKGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDEHLDLTFLQHIREVTGYVLISHVDVKRIVLPALQIIRGRTLFKLSVHDEEFALVVTLSKMHNLEMPALRDILAGSCGLFNNYNLCHMKTINWEEIITGTGSKIINVYNFTEPERECPACHESCEAGCWGEGPENCQKFSKINCSPQCHQGRCFGPRPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVCNQECPAMQRYNPITYSWETNPEGKYAYGATCVKTCPEHLLKDNGACVRICPAKKKAVNGECVVCDGPCPKTCQGVDIVHAGNIESFRDCTVIEGSISILDHSFGGFQQIYPNFTFGPRYPRLHPDRLEIFSTLQEITGFINVQASHPDFKNLSYFRNLETIGGRQLTEYFSALYIVKTSLNSLHLRSLKMIRAGSVTILENKELCFAESISWTKIIKSQLHGTLLQNNKVSQQCQESGLVCSAQCSVEGCWGLGPNECLSCAHFQLDETCVESCDLNLGIYELTPK-LCKHCHHECDETCTGPGPGN--CTVCKHVKDGPYCVPACPTSKFNDSGECVSCHDNCVGGCTGPENNIGPRGCHSCE--KAVINGDVEVD 659 HSP 2 Score: 112.849 bits (281), Expect = 1.255e-21 Identity = 50/92 (54.35%), Postives = 65/92 (70.65%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 Q QG L+PLAGKA+CR CH CK+C GYGFH+ VCQECV + + +QC EC D+Y D + C C+ ECRGC G ++C +C+NY+VYL Sbjct: 680 QEQGPLKPLAGKAVCRKCHPRCKRCIGYGFHEQVCQECVKYKRGEQCEDECPQDHYADEERHECSRCASECRGCSGPNVNQCQSCRNYRVYL 771
BLAST of EMLSAG00000007374 vs. nr
Match: gi|942367615|gb|JAN65737.1| (Receptor tyrosine-protein kinase erbB-3 [Daphnia magna]) HSP 1 Score: 845.114 bits (2182), Expect = 0.000e+0 Identity = 416/636 (65.41%), Postives = 482/636 (75.79%), Query Frame = 0 Query: 54 NPSPVEASSLGGIKSHHFRFNSQPHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK----------LEPLAGKAICRPCHSLCKK-CNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPED 673 NPSP + + N GKICIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDE+LDL+FLQHIREVTGYVLISHVDV++IVLP+LQIIRGRTLFKLSV D++F+L+VTLSKMH LEMPALRDIL GS G+ NNYNLCH+KTI WEEIITG K + VYNF EPER+C CHESC++GCWGEGP NCQKFSKINCSPQCH+GRCFG PRECCHLFCAGGCTGPKQSDCLACRNFFDDGV ECP MQRYNPI Y WE NPEGKYAYGATCVK CP+HLLKDNGACVRICP KKK VNGECV CDGPCPKTC +++HAGNI+SF++CTVIEGSI+ILD +F GFQ+ Y N+TFG RYP + P +LE+F+TL+E+TG+IN+Q HP+FKNL+ FRNLE IGGR LTEYFSALYIVKT+L SL L+SL+ IR+G+V+ILENK+LC+A+ I+W KI+KS H TLLQNNK Q+C +C QCS EGCWG G N CLSC FQ + L K +C+ CH C + C G G + C C H CVP C + DS +C C + C GC G +GP C +C+ K + G+ D Sbjct: 41 NPSPADKA------------NDVFKGKICIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDEHLDLTFLQHIREVTGYVLISHVDVKRIVLPALQIIRGRTLFKLSVHDEEFALVVTLSKMHNLEMPALRDILAGSCGLFNNYNLCHMKTINWEEIITGTGSKIINVYNFTEPERECPACHESCEAGCWGEGPENCQKFSKINCSPQCHQGRCFGPRPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVCNQECPAMQRYNPITYSWETNPEGKYAYGATCVKTCPEHLLKDNGACVRICPAKKKAVNGECVVCDGPCPKTCQGVDIVHAGNIESFRDCTVIEGSISILDHSFGGFQQIYPNFTFGPRYPRLHPDRLEIFSTLQEITGFINVQASHPDFKNLSYFRNLETIGGRQLTEYFSALYIVKTSLNSLHLRSLKMIRAGSVTILENKELCFAESISWTKIIKSQLHGTLLQNNKVSQQCQESGLVCSAQCSVEGCWGLGPNECLSCAHFQLDETCVESCDLNLGIYELTPK-LCKHCHHECDETCTGPGPGN--CTVCKHVKDGPYCVPACPTSKFNDSGECVSCHDNCVGGCTGPENNIGPRGCHSCE--KAVINGDVEVD 659 HSP 2 Score: 112.464 bits (280), Expect = 1.545e-21 Identity = 50/92 (54.35%), Postives = 65/92 (70.65%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 Q QG L+PLAGKA+CR CH CK+C GYGFH+ VCQECV + + +QC EC D+Y D + C C+ ECRGC G ++C +C+NY+VYL Sbjct: 680 QEQGPLKPLAGKAVCRKCHPRCKRCIGYGFHEQVCQECVKYKRGEQCEDECPQDHYADEERHECSRCASECRGCSGPNVNQCQSCRNYRVYL 771
BLAST of EMLSAG00000007374 vs. nr
Match: gi|1022765368|gb|KZS10602.1| (putative Epidermal growth factor receptor [Daphnia magna]) HSP 1 Score: 844.729 bits (2181), Expect = 0.000e+0 Identity = 408/610 (66.89%), Postives = 474/610 (77.70%), Query Frame = 0 Query: 80 KICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESCQSGCWGEGPSNCQKFSKINCSPQCHKGRCFGELPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTLLQNNKNPQECIRQDHMCDPQCSAEGCWGPGNNSCLSCKKFQTQGK----------LEPLAGKAICRPCHSLCKK-CNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTKCKPCSEECR-GCYG----MGPDKCLACKNYKVYLTGEFPED 673 ++CIGT GRMSVP+NREHHYRNLRDRYTNCTYVDGNLELTWLQDE+LDL+FLQHIREVTGYVLISHVDV++IVLP+LQIIRGRTLFKLSV D++F+L+VTLSKMH LEMPALRDIL GS G+ NNYNLCH+KTI WEEIITG K + VYNF EPER+C CHESC++GCWGEGP NCQKFSKINCSPQCH+GRCFG PRECCHLFCAGGCTGPKQSDCLACRNFFDDGV ECP MQRYNPI Y WE NPEGKYAYGATCVK CP+HLLKDNGACVRICP KKK VNGECV CDGPCPKTC +++HAGNI+SF++CTVIEGSI+ILD +F GFQ+ Y N+TFG RYP + P +LE+F+TL+E+TG+IN+Q HP+FKNL+ FRNLE IGGR LTEYFSALYIVKT+L SL L+SL+ IR+G+V+ILENK+LC+A+ I+W KI+KS H TLLQNNK Q+C +C QCS EGCWG G N CLSC FQ + L K +C+ CH C + C G G + C C H CVP C + DS +C C + C GC G +GP C +C+ K + G+ D Sbjct: 37 RVCIGTNGRMSVPSNREHHYRNLRDRYTNCTYVDGNLELTWLQDEHLDLTFLQHIREVTGYVLISHVDVKRIVLPALQIIRGRTLFKLSVHDEEFALVVTLSKMHNLEMPALRDILAGSCGLFNNYNLCHMKTINWEEIITGTGSKIINVYNFTEPERECPACHESCEAGCWGEGPENCQKFSKINCSPQCHQGRCFGPRPRECCHLFCAGGCTGPKQSDCLACRNFFDDGVCNQECPAMQRYNPITYSWETNPEGKYAYGATCVKTCPEHLLKDNGACVRICPAKKKAVNGECVVCDGPCPKTCQGVDIVHAGNIESFRDCTVIEGSISILDHSFGGFQQIYPNFTFGPRYPRLHPDRLEIFSTLQEITGFINVQASHPDFKNLSYFRNLETIGGRQLTEYFSALYIVKTSLNSLHLRSLKMIRAGSVTILENKELCFAESISWTKIIKSQLHGTLLQNNKVSQQCQESGLVCSAQCSVEGCWGLGPNECLSCAHFQLDETCVESCDLNLGIYELTPK-LCKHCHHECDETCTGPGPGN--CTVCKHVKDGPYCVPACPTSKFNDSGECVSCHDNCVGGCTGPENNIGPRGCHSCE--KAVINGDVEVD 641 HSP 2 Score: 113.62 bits (283), Expect = 7.724e-22 Identity = 50/92 (54.35%), Postives = 65/92 (70.65%), Query Frame = 0 Query: 577 QTQGKLEPLAGKAICRPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDYYKDSTK--CKPCSEECRGCYGMGPDKCLACKNYKVYL 666 Q QG L+PLAGKA+CR CH CK+C GYGFH+ VCQECV + + +QC EC D+Y D + C C+ ECRGC G ++C +C+NY+VYL Sbjct: 662 QEQGPLKPLAGKAVCRKCHPRCKRCIGYGFHEQVCQECVKYKRGEQCEDECPQDHYADEERHECSRCASECRGCSGPNVNQCQSCRNYRVYL 753
BLAST of EMLSAG00000007374 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold545_size140784-snap-gene-0.21 (protein:Tk11083 transcript:maker-scaffold545_size140784-snap-gene-0.21-mRNA-1 annotation:"epidermal growth factor partial") HSP 1 Score: 233.802 bits (595), Expect = 4.126e-72 Identity = 113/153 (73.86%), Postives = 126/153 (82.35%), Query Frame = 0 Query: 41 RILLLLLCIVLWKNPSPVEASSLGGIKSHHFRFNSQ-PHGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALR 192 R+L L L + +W P EA ++ + HGKICIGT GRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDV +IVLPSLQIIRGRTLFKLSV++D+F+L+VTLSKMH LE+PALR Sbjct: 7 RLLYLGLVLGIW----PSEAVRTRDVRPEEAEDDKNLRHGKICIGTSGRMSVPNNREHHYRNLRDRYTNCTYVDGNLELTWLQDENLDLSFLQHIREVTGYVLISHVDVTRIVLPSLQIIRGRTLFKLSVQEDEFALIVTLSKMHNLELPALR 155
BLAST of EMLSAG00000007374 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold383_size189472-snap-gene-0.28 (protein:Tk11344 transcript:maker-scaffold383_size189472-snap-gene-0.28-mRNA-1 annotation:"insulin receptor-2") HSP 1 Score: 91.6633 bits (226), Expect = 6.811e-19 Identity = 119/475 (25.05%), Postives = 197/475 (41.47%), Query Frame = 0 Query: 78 HGKICIGTKGRMSVPNNREHHYRNLRDRYTNCTYVDGNLEL-----TWLQDENLD----LSFLQHIREVTGYVLISHVD---VRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSKMHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDCTPCHESC-QSG--------CWGEGPSNCQKFSKINCSPQ---CHKGRCFGELPRECCHLFCAGGC---TGPKQSDCLACRNFFDDGVXKXECPP----MQRYNPIKY-------RWEKNPEGKYAYGATCVKECP----------KHLLKD-NGACVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKI 503 HG++C G +++ + Y +L NCT ++GN+ + T+ E ++ L+F +I+E+T Y+LI D + P+L +IRG L S ++ + + + +L IL G V I N LC++ TI WE I++ + + + E C C Q G CW + ++CQK C+ + CH GE+ E C C GGC +G + C +C++ + ECP + N I + + + + +Y ++CP K KD G C+R CP K G C+ C CP C EV +++ CT+I+G++ I S N Q K E + ++ + G + I + +L+ F +LEVI G+ + FS LT L ++LRK+ Sbjct: 31 HGEVC----GSITLNSTNLSDYIHLE----NCTVIEGNVGVMIGLETFEPPEEVEVLARLTF-PNIQEITDYLLIYRADKLTSLSRLFPNLTVIRGNELLGESALT-----ILQNENLKDIGLKSLTTILRGGVTIKGNPLLCYVHTINWERIVSRAFFGNLEIEDGYESTLCPFECPGRCPQDGREHGKMRLCWNK--NHCQKIQLEQCTTEDAHCHLDSQ-GEV--EVCSRNCLGGCSRHSGSNHTLCRSCQDVRTPDGCRSECPQDFLLVITANLIMFPLFVIFCQCQHSVFQYKSYRCISKEDCPNIGNQYVGEVKTTFKDYQGKCLRQCPHNTKEEEGTCITCSDDCPTVCGGAEVTTIQDLEKLNGCTIIKGTLAIQLSGKNVVQ-----------------KLEEALSKVRIIEGSLKISRVF-SLISLDFFTSLEVIEGKDHGQEFS--------LTLLNNENLRKL 460 HSP 2 Score: 57.3806 bits (137), Expect = 2.170e-8 Identity = 68/258 (26.36%), Postives = 105/258 (40.70%), Query Frame = 0 Query: 398 FQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEV-----FTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTA-LTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSPSHNTL-LQNNKNPQECIRQDHMCDPQCSAEG--------CWGPGNNSCLSCKKFQTQG--------KLEPLAGKAIC-RPCHSLCKKCNGYGFHDDVCQECVHFSQDQQCVPECDGDY 631 +NCTVIEG++ ++ E +E P+++EV F ++E+T Y+ I F NL VI G L SAL I++ L +GLKSL I G V+I N LCY INW++I+ L +++ C + C +C +G CW + C+K Q + L+ +C R C C + +G + +C+ C C EC D+ Sbjct: 51 LENCTVIEGNVGVMIGL-----ETFE-----------PPEEVEVLARLTFPNIQEITDYLLIYRADKLTSLSRLFPNLTVIRGNELLGE-SALTILQNENLKDIGLKSLTTILRGGVTIKGNPLLCYVHTINWERIVSRAFFGNLEIEDGYESTLCPFE---CPGRCPQDGREHGKMRLCWNKNH-----CQKIQLEQCTTEDAHCHLDSQGEVEVCSRNCLGGCSRHSGS--NHTLCRSCQDVRTPDGCRSECPQDF 281
BLAST of EMLSAG00000007374 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold892_size84543-snap-gene-0.16 (protein:Tk08291 transcript:maker-scaffold892_size84543-snap-gene-0.16-mRNA-1 annotation:"insulin receptor-like isoform x2") HSP 1 Score: 80.4925 bits (197), Expect = 1.675e-15 Identity = 95/421 (22.57%), Postives = 179/421 (42.52%), Query Frame = 0 Query: 109 CTYVDGNL------ELTWLQDENL--DLSFLQHIREVTGYVLI---SHVDVRKIVLPSLQIIRGRTLFKLSVRDDKFSLMVTLSK-MHYLEMPALRDILEGSVGILNNYNLCHIKTIEWEEIITGPRGKYVYVYNFNEPERDC--TPCHESC-------QSGCWGEGPSNCQKFSKINCSPQCHKGRCF--GELPRECCHLFCAGGCTGPKQSDCLACRNFFDDG----------------------VXKXECPPMQRYNPIKYRWEKNPEGKYAYGATCVKECPKHLLKDNGA-CVRICPPKKKTVNGECVPCDGPCPKTCHFNEVMHAGNIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFS 483 CT ++GNL E +++E+ +L+F ++E+T Y+L+ S + + P+L +IRG L ++L+V ++ + + L +L G V ++ N +LC+I++I W+EII ++ +F E R C C + C + CW E S+CQ+ + CF + C C GGC+ C ACR+ D + K +C M+ YN +++ K +Y + C++ CP+ ++ G V C +C+ C PC + ++ F++CT + + L+ T E + + +R +++ L+ F++LK++ G +Q + N K F +L ++ L + F+ Sbjct: 314 CTVIEGNLVIMSGFETMEVKEEDYITNLTF-PDLKEITDYMLVYKASRIVTFSKLFPNLSVIRGNKLL------GNWALVVFQNENLVNIGFKGLTRLLHGGVKVMENPSLCYIESINWKEIINSDYHSHI---DFEENNRFCPGLKCSQLCPTEEPTGRRLCWTE--SDCQRVERKCDESVDSDNICFTNNDGTVNTCSSECLGGCSSHDSKICWACRHVRWDSNQEIKCSNECPLPLLVYKDWRCINKSDCSHMETYNHAGAGFKEGLSFK-SYDSKCIEHCPRDTKEEIGKDGVPTCK--------QCIDCPNPCDGGV----ITSLEDLKLFEDCTHVPNVVQHLERTLGRVIE-IQGFLKISRVFSLN--SLDFFSSLKKILG---VQANEENSK----FYSLIILENENLRKLFT 699 HSP 2 Score: 70.8626 bits (172), Expect = 1.505e-12 Identity = 45/150 (30.00%), Postives = 70/150 (46.67%), Query Frame = 0 Query: 394 NIDSFQNCTVIEGSITILDSTFNGFQEXYENYTFGNRYPAMDPKKLEVFTTLKEVTGYINIQGHHPNFKNLNAFRNLEVIGGRTLTEYFSALYIVKTALTSLGLKSLRKIRSGAVSILENKDLCYAQEINWQKIMKSP--SHNTLLQNNK 541 N + CTVIEG++ I+ S F + E+Y +P LKE+T Y+ + F NL VI G L ++ + L ++G K L ++ G V ++EN LCY + INW++I+ S SH +NN+ Sbjct: 307 NFGDLEGCTVIEGNLVIM-SGFETMEVKEEDYITNLTFP-----------DLKEITDYMLVYKASRIVTFSKLFPNLSVIRGNKLLGNWALVVFQNENLVNIGFKGLTRLLHGGVKVMENPSLCYIESINWKEIINSDYHSHIDFEENNR 444 The following BLAST results are available for this feature:
BLAST of EMLSAG00000007374 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000007374 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
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BLAST of EMLSAG00000007374 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 3
BLAST of EMLSAG00000007374 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 25
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BLAST of EMLSAG00000007374 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 25
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BLAST of EMLSAG00000007374 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000007374 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 3
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s41:164202..216377- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000007374-690140 ID=EMLSAG00000007374-690140|Name=EMLSAG00000007374|organism=Lepeophtheirus salmonis|type=gene|length=52176bp|location=Sequence derived from alignment at LSalAtl2s41:164202..216377- (Lepeophtheirus salmonis)back to top Add to Basket
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