EMLSAG00000008403, EMLSAG00000008403-691169 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:Npc1a "Niemann-Pick type C-1a" species:7227 "Drosophila melanogaster" [GO:0005765 "lysosomal membrane" evidence=ISS] [GO:0030301 "cholesterol transport" evidence=ISS] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0007591 "molting cycle, chitin-based cuticle" evidence=IMP] [GO:0016125 "sterol metabolic process" evidence=IMP] [GO:0045456 "ecdysteroid biosynthetic process" evidence=IMP] [GO:0032374 "regulation of cholesterol transport" evidence=IDA] [GO:0007291 "sperm individualization" evidence=IMP] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0007291 GO:GO:0007591 GO:GO:0032374 GO:GO:0016125 GO:GO:0030301 GO:GO:0008158 GO:GO:0045456 eggNOG:NOG149152 OrthoDB:EOG7QRQT0 TIGRFAMs:TIGR00917 ChiTaRS:NPC1 EMBL:BT009977 ProteinModelPortal:Q7YU59 SMR:Q7YU59 STRING:7227.FBpp0079547 PaxDb:Q7YU59 PRIDE:Q7YU59 FlyBase:FBgn0024320 InParanoid:Q7YU59 Bgee:Q7YU59 Uniprot:Q7YU59) HSP 1 Score: 460.299 bits (1183), Expect = 1.283e-140 Identity = 266/632 (42.09%), Postives = 377/632 (59.65%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFV--GVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSN-----ACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+ PFQI ++ K S + N PCN V+ K P CSC+DC+ SC Q + + L+ MA +FL+G L+F+ + T + + + D D++D + +S + + G + +L FFT+WGT+ A+ P + + + L GI ++ +TTDP++LWASP S+SR E++FFD F PFYR+ Q+IIKA NL + G FGP+F + EFL +L LQ+ I++I N LKDIC+ PL+ + C +Q++W Y+ DD + LD +++ N TYLD C NP C++ G P+ P LGGFL + K+ ANA+++TFL+ N++ + L A+ WEK F+EF+ + +N +++MDIAFTSERSI DE+++E+ D+ TI +SYLIMF+YI +SLG KR I+SKITL IGGV+IV+ SV +SVG+FG+I PATLII E+IPFLVLA G DNIF+LVQ QR + ET ++ +GRI+G V PS+LLTS +ES CFFLG +S MPAVRAFALYAG+AL+IDF +QITCF+SL LD R+ EN DI +I+G
Sbjct: 205 YVPFQITYIQHEPKSNS--NNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCP-QGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFLMGSFLFTQGSSMDDNFQVDGNDVSD----EMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGPYT-FGPVFDR-EFLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDD--HDEDNGFNVTYLDALYDCISNPYL----------CLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKT-------DLENALTWEKKFVEFMTNYTKN-NMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSILLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKG 805 HSP 2 Score: 216.853 bits (551), Expect = 2.113e-56 Identity = 120/286 (41.96%), Postives = 170/286 (59.44%), Query Frame = 0
Query: 662 EKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGP--MAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAI-NRNVTNENQKA-----RVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
+ Y+ D Y W SS K + C +C + T + L P F +YL +FL+DNP C KAGHAAY ++ + ++ AS FM +HTILKSS DY+ AL +R++++ I + R ++N A VFPYS+FYVFYEQYLTMW DT++S+ IS +SIF+VTF+ GF++ S+L++++TI MI NL G+MY WNISLNA+SLVNLVMA+GIS+EFCSH V F + V+++ R+ +L +GSS+
Sbjct: 933 QTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCPHQDTSCLRC----NITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAYGGAVRYS-------NSHERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADSLSKMGSSI 1207
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:NPC1 "Niemann-Pick type C1 protein" species:10029 "Cricetulus griseus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 KO:K12385 CTD:4864 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF182744 RefSeq:NP_001233616.1 ProteinModelPortal:Q9JLG3 GeneID:100689424 KEGG:cge:100689424 Uniprot:Q9JLG3) HSP 1 Score: 420.239 bits (1079), Expect = 5.065e-126 Identity = 243/603 (40.30%), Postives = 348/603 (57.71%), Query Frame = 0
Query: 33 CNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
CN V+ PCSC DC C + + + L+ M + ++ IF G ++ F+ E++ D N SS T + G D+ L FT+WG FC P VIF S++ +G+ ++RVTT+P+ELW++P SR+R EK++FD+ FGPF+R+ Q+II+A N S YE G FGP +K E L +L LQ IE I T N V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF ++NY + KL A WEK FI+F+ + +NP ++ I+F +ERSI DE+++E+ D+ TI ISY IMF+YI+L+LG SC R L++SKI+L I G+LIV+ SV S+G+F ++ P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GRI+G+V P+M L+SF+E++ FF GA+S MPAV F+L+AG+A+LIDF +QITCF+SL+ LDI RQ +N DI + G
Sbjct: 227 CNESVDEVTGPCSCQDCSIVCGPKPQP-PPTPVPWRILGLDAMYVIMWVTYMAFLFIFFGGLLAVWCHRRRYFVSEYTP----IDSNIAFSSNTSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCVIFFSLVFITACSSGLVFVRVTTNPVELWSAPHSRARLEKEYFDKHFGPFFRMEQLIIQAPNTSEHIYEPYPSGSDVSFGPPLNK-EILHQVLDLQIAIESITTSYNNKTVTLQDICVAPLSPYNKNCTIISVLNYFQNSHSVLDHQVGDDFYVYAD-YHTHFLYCVRAPTSLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVSNYYN------DTEKLQRAQAWEKEFIDFVKSY-KNP----NLTISFIAERSIEDELNRESNSDVFTIAISYAIMFLYISLALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGVFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGLAVLIDFLLQITCFVSLLGLDIKRQEKNRLDILCCVGG 803 HSP 2 Score: 196.823 bits (499), Expect = 5.474e-50 Identity = 108/235 (45.96%), Postives = 149/235 (63.40%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C T E K P F ++L FL DNP C K GHAAYS ++ I + D + V A+ FMT+HT+LK+S DY +A++ ++ +A I +N +N RVFPYS+FYVFYEQYLT+ DTI +L +S SIF+VT + G EL S++I+ +TI MI N+ G+M+LW+ISLNA+SLVNLVM+ GIS+EFCSH + F +RV R+E L ++GSS+
Sbjct: 976 CIRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYSSAVNI-----IGDDTY----VGATYFMTYHTVLKTSADYIDAMKKAQLVARNITETMNSKGSNY----RVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWDISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSV 1197
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:NPC1 "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0005576 "extracellular region" evidence=IEA] [GO:0005635 "nuclear envelope" evidence=IEA] [GO:0005765 "lysosomal membrane" evidence=IEA] [GO:0005768 "endosome" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006486 "protein glycosylation" evidence=IEA] [GO:0006897 "endocytosis" evidence=IEA] [GO:0006914 "autophagy" evidence=IEA] [GO:0007628 "adult walking behavior" evidence=IEA] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=IEA] [GO:0016242 "negative regulation of macroautophagy" evidence=IEA] [GO:0031982 "vesicle" evidence=IEA] [GO:0033344 "cholesterol efflux" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0045121 "membrane raft" evidence=IEA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IEA] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IEA] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0030301 GO:GO:0008158 GeneTree:ENSGT00680000099777 OrthoDB:EOG7QRQT0 TreeFam:TF300416 TIGRFAMs:TIGR00917 EMBL:AADN03002550 Ensembl:ENSGALT00000024240 Uniprot:F1NQT4) HSP 1 Score: 417.542 bits (1072), Expect = 5.763e-125 Identity = 249/639 (38.97%), Postives = 362/639 (56.65%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKS-PCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEFSIRADCTDMNDTGSSKTFFSR-TINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLF-----GETKEFGPIFHKYEFLLPLLRLQKEIEKIETQ-DNK-VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
TPF I +FS M+ N + CN V+ + PCSC DC C + + + L+ M I ++ LIF +V F+ E++ D N S+ + I + GE + L + FT WG FC P PVI SV+ C+G +++ TT+P++LW++P S++R+EK++FD+ FGPF+R Q+II+A N + D++ G FGP +K + L +L LQ I I DN+ V LKDIC PL P +N C I ++ +Y+Q+ LD + +D + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VIT +NNY S+ K+ A+ WEK FI F+ + NP ++ I+F++ERSI DEI++E+ D++T+ ISY++MFVYI+++LG S R L++SKI+L I G+LIV+ SV S+GIF + P TLI+ E+IPFLVLA G DN+F++VQ QR ET + IGR++GDV PSM L+SF+E+ FFLG +S MPAVR F+L+AGMA+LIDF +Q+TCF+SL+ LDI RQ N DI I+G
Sbjct: 209 QTPFSIIPIFSDAPV----HGMNPMNNATKGCNESVDDSTGPCSCQDCSIVCGPKPQP-PPLPAPWLLFGLDAVYIIMWISYMGFLLIFFALVFGVWCYRRRHFVSEYTP----IDSNVAFSANSHRDNGKITCGERLGERFENGLRMTFTSWGAFCVRNPRPVILFSVVFIAMCCSGFVYIKATTNPVDLWSAPSSQARKEKEYFDKHFGPFFRTEQLIIQAPN----SHPDIYSPYPSGADVPFGPPLNK-DILHQVLDLQDAIVNIAASFDNETVTLKDICLAPLAPYNNNCTILSVLNYFQNSHSVLDHSVGDDFFVYAD-YHTHFLYCVRAPASLNDTSLLHDPCLGAFGGPVFPWLVLGGYDGDN--------YNNATALVITLPVNNYYNDSK------KIMKALAWEKEFINFLKNY-DNP----NLTISFSAERSIEDEINRESRSDVSTVVISYVVMFVYISIALGHIQSWGRLLVDSKISLGIAGILIVLSSVACSIGIFSYFGVPVTLIVAEVIPFLVLAIGVDNLFIIVQTLQRDERLEGETLDKQIGRVLGDVAPSMFLSSFSETVAFFLGTLSTMPAVRTFSLFAGMAVLIDFILQVTCFVSLLGLDIRRQERNRLDILCCIKG 813 HSP 2 Score: 190.274 bits (482), Expect = 6.518e-48 Identity = 105/235 (44.68%), Postives = 147/235 (62.55%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C + E K P F +L FL DNP C K GHAAYS ++ + K + DV A+ FMT+HT+LK S DY +A++ +R +A I + + + RVFPYS+FYVFYEQYLT+ D I +LCIS SIF+VT + GFE+ +++++ VTI MI N+ G+M+LW ISLNA+SLVNLVM+ GI++EFCSH + F +RV+R+E L ++GSS+
Sbjct: 986 CTRCRPLSQEGKQRPQGEDFMTFLPMFLSDNPNPKCGKGGHAAYSSAVDLIKN---------KTDVGATYFMTYHTVLKKSSDYIDAMKKARDIADNITETMGI----KEKNYRVFPYSVFYVFYEQYLTIVNDAIFNLCISLGSIFLVTAVLLGFEVWAAVVVTVTIAMIIVNMFGVMWLWGISLNAVSLVNLVMSCGIAVEFCSHVTRAFTVSTKGSRVERAEEALSHMGSSV 1207
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:Npc1 "Niemann-Pick type C1" species:10090 "Mus musculus" [GO:0005515 "protein binding" evidence=IPI] [GO:0005576 "extracellular region" evidence=IDA] [GO:0005635 "nuclear envelope" evidence=ISO;IDA] [GO:0005764 "lysosome" evidence=IDA] [GO:0005765 "lysosomal membrane" evidence=ISO] [GO:0005768 "endosome" evidence=IDA] [GO:0005783 "endoplasmic reticulum" evidence=ISO] [GO:0005794 "Golgi apparatus" evidence=IDA] [GO:0005886 "plasma membrane" evidence=IDA] [GO:0005887 "integral component of plasma membrane" evidence=ISO] [GO:0006486 "protein glycosylation" evidence=ISO;IDA] [GO:0006629 "lipid metabolic process" evidence=IEA] [GO:0006897 "endocytosis" evidence=IMP] [GO:0006914 "autophagy" evidence=ISO] [GO:0007628 "adult walking behavior" evidence=IGI] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0008202 "steroid metabolic process" evidence=IEA] [GO:0008203 "cholesterol metabolic process" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=ISO] [GO:0016020 "membrane" evidence=IDA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016242 "negative regulation of macroautophagy" evidence=IGI;IMP] [GO:0030301 "cholesterol transport" evidence=ISO] [GO:0031982 "vesicle" evidence=IDA] [GO:0033344 "cholesterol efflux" evidence=ISO;IMP] [GO:0042493 "response to drug" evidence=IDA] [GO:0042632 "cholesterol homeostasis" evidence=ISO] [GO:0045121 "membrane raft" evidence=IDA] [GO:0046686 "response to cadmium ion" evidence=ISO] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISO] [GO:0060548 "negative regulation of cell death" evidence=ISO] [GO:0070062 "extracellular vesicular exosome" evidence=ISO] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IDA] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IDA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 EMBL:AF003348 MGI:MGI:1097712 GO:GO:0005783 GO:GO:0005794 GO:GO:0046686 GO:GO:0048471 GO:GO:0007165 GO:GO:0005576 GO:GO:0005887 GO:GO:0005635 GO:GO:0006914 GO:GO:0045121 GO:GO:0031902 GO:GO:0005765 GO:GO:0042493 GO:GO:0008206 GO:GO:0005768 GO:GO:0006486 GO:GO:0008203 GO:GO:0006897 GO:GO:0005764 GO:GO:0015485 GO:GO:0033344 GO:GO:0042632 GO:GO:0007628 GO:GO:0031982 GO:GO:0060548 GO:GO:0007041 GO:GO:0008158 GO:GO:0071404 GO:GO:0071383 GO:GO:0016242 EMBL:AC102248 eggNOG:NOG149152 GeneTree:ENSGT00680000099777 KO:K12385 OrthoDB:EOG7QRQT0 CTD:4864 HOVERGEN:HBG003913 TreeFam:TF300416 TIGRFAMs:TIGR00917 EMBL:AF003349 EMBL:AC102096 EMBL:CH466622 PIR:T30188 RefSeq:NP_032746.2 UniGene:Mm.3484 ProteinModelPortal:O35604 SMR:O35604 ChEMBL:CHEMBL2321610 PhosphoSite:O35604 PaxDb:O35604 PRIDE:O35604 Ensembl:ENSMUST00000025279 GeneID:18145 KEGG:mmu:18145 UCSC:uc008ecb.1 HOGENOM:HOG000036674 InParanoid:O35604 OMA:ITRAFTM ChiTaRS:NPC1 NextBio:293400 PRO:PR:O35604 ArrayExpress:O35604 CleanEx:MM_NPC1 Genevestigator:O35604 Uniprot:O35604) HSP 1 Score: 417.542 bits (1072), Expect = 6.422e-125 Identity = 238/603 (39.47%), Postives = 347/603 (57.55%), Query Frame = 0
Query: 33 CNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
CN V+ PCSC DC C + + + + L+ M + ++ +F G ++ F+ E++ D N S + + G D+ L FT+WG FC P +IF S+ +G+ +++VTT+P+ELW++P S++R EK++FD+ FGPF+R Q+II+A N S YE G FGP +K E L +L LQ IE I N V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY + +L A WEK FI F+ + +NP ++ I+FT+ERSI DE+++E+ D+ T+ ISY++MF+YI+L+LG SC R L++SKI+L I G+LIV+ SV S+GIF ++ P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GRI+G+V P+M L+SF+E++ FF GA+S MPAV F+L+AGMA+LIDF +QITCF+SL+ LDI RQ +N DI +RG
Sbjct: 227 CNESVDEVTGPCSCQDCSIVCGPKPQP-PPPPMPWRIWGLDAMYVIMWVTYVAFLFVFFGALLAVWCHRRRYFVSEYTP----IDSNIAFSVNSSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNK-EILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYAD-YHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYN------DTERLQRAWAWEKEFISFVKNY-KNP----NLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVRG 803 HSP 2 Score: 195.282 bits (495), Expect = 1.577e-49 Identity = 107/235 (45.53%), Postives = 147/235 (62.55%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C T E K P F ++L FL DNP C K GHAAY ++ I + D + + A+ FMT+HTILK+S DY +A++ +R +AS I + ++ RVFPYS+FYVFYEQYLT+ DTI +L +S SIF+VT + G EL S++I+ +TI MI N+ G+M+LW ISLNA+SLVNLVM+ GIS+EFCSH + F +RV R+E L ++GSS+
Sbjct: 976 CVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYGSAVNI-----VGDDTY----IGATYFMTYHTILKTSADYTDAMKKARLIASNITETMR----SKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSV 1197
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:npc1 "Niemann-Pick disease, type C1" species:7955 "Danio rerio" [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016020 "membrane" evidence=IEA] [GO:0030301 "cholesterol transport" evidence=IEA] [GO:0001666 "response to hypoxia" evidence=IDA] [GO:0006869 "lipid transport" evidence=ISS] [GO:0055113 "epiboly involved in gastrulation with mouth forming second" evidence=IMP] [GO:0035855 "megakaryocyte development" evidence=IMP] [GO:0009790 "embryo development" evidence=IMP] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 ZFIN:ZDB-GENE-030131-3161 GO:GO:0016021 GO:GO:0007165 GO:GO:0001666 GO:GO:0006869 GO:GO:0035855 GO:GO:0055113 GO:GO:0030301 GO:GO:0008158 TIGRFAMs:TIGR00917 EMBL:JF951427 UniGene:Dr.108239 Uniprot:F6N6I8) HSP 1 Score: 417.157 bits (1071), Expect = 7.106e-125 Identity = 245/636 (38.52%), Postives = 369/636 (58.02%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIP-EEMSYYNTEIEPCNIRVN-GKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNA------GEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCT-GIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKI--ETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQR--YGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIR 624
PF I+ +F+ +P + M+ N C+ ++ G PCSC DC C + + L+ SF M ++ LIF GVV+ + + + + + D+ + S + I A GE + L + F+RWG+ C P+ +I LS L+ + +C+ G+ ++R+TT+P+ELW++P SR+RQEK+ FD+ FGPF+R Q+II + + G+ F PI + L +L LQ EIE + E + V LKDIC +PL+P ++ C I ++ +Y+Q+ + LD ++ +ND Y H + C+ +P S + + CM G P+ P+ VLGG+ + Y+ A A+ TF + N + KL A+ WEK FI F+ + +NP ++ ++F+SERSI DEI +E+ D++TI ISY+IMFVYI+++LG SC+ L++SKI+L I G+LIV+ SV S+GIF +I P TLI+ E+IPFLVLA G DNIF++VQ QR PE E HQ+ IGRI+GDV PSM L+SF+E+ FFLGA+S MPAVR F+L+AG+A+ IDF +QI+CF+SL+ LDI RQ N DI ++
Sbjct: 199 QVPFGIEPIFT-----DVPVQGMTPMNNRTFNCSQSLDDGSEPCSCQDCSEVCGPTPVP-PPIPPPWIILGLDAMSFIMWCSYIAFLLIFFGVVLGAWCYRRSVVTXEYGPILDSNQPHSLNSDGTDLIDEASCCETVGERFENSLRLVFSRWGSLCVRQPLTII-LSSLVLICICSAGLSYMRITTNPVELWSAPSSRARQEKNCFDQHFGPFFRTEQLIITTPWTEEGGFSTITGDIIPFSPILN-LSLLHQVLDLQLEIENLIAEYKGENVTLKDICVSPLSPYNDNCTILSVLNYFQNSHEVLDHEFQDEFFLYND-YHTHLLYCASSPTSLDDTSRLHDPCMGTFGGPVFPWLVLGGY--------EDSAYNNATALFFTFPVTNC------LNDTEKLGKALAWEKEFIRFMKNY-ENP----NLTVSFSSERSIEDEIDRESNSDVSTIVISYIIMFVYISVALGRINSCRTLLVDSKISLGIAGILIVLSSVACSLGIFSYIGIPLTLIVIEVIPFLVLAVGVDNIFIIVQTYQRDERMPEE-ELHQQ-IGRILGDVAPSMFLSSFSETVAFFLGALSTMPAVRTFSLFAGLAIFIDFLLQISCFVSLLGLDIKRQEANRMDILCCVK 804 HSP 2 Score: 197.978 bits (502), Expect = 2.473e-50 Identity = 104/237 (43.88%), Postives = 151/237 (63.71%), Query Frame = 0
Query: 705 QKCPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
+ C + T K P F +L FL DNP + C K GHAAY ++ +K DV A+ FM++HTILK+S D+ A++M+R E+ + I + ++ ++ +VFPYS+FYVFYEQYLT+ DT +L +S +IFIVT + GFEL S++++ TI MI N+ G+M+LW+ISLNA+SLVNLVM+ GIS+EFCSH V+ F +RV+R+E L ++GSS+
Sbjct: 974 KSCVHCRPMTSSGKQRPNGTEFMHFLPMFLSDNPNIKCGKGGHAAYGTAVDLKDN---------NTDVGATYFMSYHTILKNSSDFINAMKMAR----ELTDNITQTLSTHDKSYKVFPYSVFYVFYEQYLTIVDDTALNLGVSLSAIFIVTAVLLGFELWSAVLVCFTIAMILINMFGVMWLWSISLNAVSLVNLVMSCGISVEFCSHIVRAFSISTRSSRVERAEEALAHMGSSV 1197
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:Npc1 "RCG41239" species:10116 "Rattus norvegicus" [GO:0005576 "extracellular region" evidence=IEA] [GO:0005635 "nuclear envelope" evidence=IEA] [GO:0005768 "endosome" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006486 "protein glycosylation" evidence=IEA] [GO:0006897 "endocytosis" evidence=IEA] [GO:0006914 "autophagy" evidence=IEA] [GO:0007628 "adult walking behavior" evidence=IEA] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=IEA] [GO:0016242 "negative regulation of macroautophagy" evidence=IEA] [GO:0031982 "vesicle" evidence=IEA] [GO:0033344 "cholesterol efflux" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0045121 "membrane raft" evidence=IEA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IEA] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IEA] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 RGD:628693 GO:GO:0005783 GO:GO:0005794 GO:GO:0046686 GO:GO:0048471 GO:GO:0007165 GO:GO:0005576 GO:GO:0005887 GO:GO:0005635 GO:GO:0006914 GO:GO:0045121 GO:GO:0042493 GO:GO:0005768 GO:GO:0006486 GO:GO:0006897 GO:GO:0005764 GO:GO:0015485 GO:GO:0033344 GO:GO:0007628 GO:GO:0031982 GO:GO:0060548 GO:GO:0008158 GO:GO:0071404 GO:GO:0071383 GO:GO:0016242 GeneTree:ENSGT00680000099777 KO:K12385 OrthoDB:EOG7QRQT0 CTD:4864 TreeFam:TF300416 TIGRFAMs:TIGR00917 OMA:ITRAFTM EMBL:CH474073 EMBL:AABR06093698 EMBL:AABR06093699 EMBL:AABR06093700 RefSeq:NP_705888.2 UniGene:Rn.115253 Ensembl:ENSRNOT00000016167 GeneID:266732 KEGG:rno:266732 NextBio:624576 PRO:PR:G3V7K5 Uniprot:G3V7K5) HSP 1 Score: 415.616 bits (1067), Expect = 3.063e-124 Identity = 249/635 (39.21%), Postives = 358/635 (56.38%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGP 626
PF I VFS D E M + CN V+ PCSC DC + C + + + L+ M + ++ ++F G ++ F+ E++ D N SS + + G D+ L FT+WG FC P +IF S++ +G+ +++VTT+P+ELW++P S++R EK++FD+ FGPF+R Q+II+A N S YE G FGP +K E L +L LQ IE I N V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY + KL A WEK FI F+ + +NP ++ I+FT+ERSI DE+++E+ D+ T+ ISY +MF+YI+L+LG S R L++SKI+L I G+LIV+ SV S+GIF +I P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GRI+G+V P+M L+SF+E++ FF GA+S MPAV F+L+AGMA+LIDF +QITCF+S + LDI RQ +N DI +RGP
Sbjct: 201 QAPFTIIPVFS-DLSVLGMEPM---RNATKGCNESVDEVTGPCSCQDCSAVCGPKPQP-PPPPVPWRILGLDAMYVIMWVAYMAFLVLFFGGLLAVWCHRRRYFVSEYTP----IDSNIAFSSNSSDKGEASCCDPLGVAFDDCLRRMFTKWGAFCVRNPTCIIFFSLVFIAACSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNSSVHIYEPYPSGADVPFGPPLNK-EILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDNQVGDDFFVYAD-YHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYN------DTEKLQRAWAWEKEFINFVKNY-KNP----NLTISFTAERSIEDELNRESNSDVFTVLISYAVMFLYISLALGHIQSWNRVLVDSKISLGIAGILIVLSSVTCSLGIFSYIGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSFLGLDIKRQEKNRLDILCCVRGP 805 HSP 2 Score: 194.512 bits (493), Expect = 2.497e-49 Identity = 108/235 (45.96%), Postives = 146/235 (62.13%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C T E K P F ++L FL DNP C K GHAAYS ++ I + D + + A+ FMT+HTILK+S DY +AL+ +R +AS I + ++ RVFPYS+FYVFYEQYLT+ D I +L +S SIF+VT + G EL S++I+ +TI MI N+ G+M+LW ISLNA+SLVNLVM GIS+EFCSH + F +RV R+E L ++GSS+
Sbjct: 977 CVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYSSAVNI-----MGDDTY----IGATYFMTYHTILKTSADYIDALKKARLIASNITETMR----SKGSDYRVFPYSVFYVFYEQYLTIIDDAIFNLSVSLGSIFLVTLVALGCELWSAVIMCLTIAMILVNMFGVMWLWGISLNAVSLVNLVMTCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSV 1198
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:Npc1 "Niemann-Pick disease, type C1" species:10116 "Rattus norvegicus" [GO:0005576 "extracellular region" evidence=IEA;ISO] [GO:0005635 "nuclear envelope" evidence=IEA;ISO] [GO:0005764 "lysosome" evidence=ISO] [GO:0005765 "lysosomal membrane" evidence=IEA;ISO] [GO:0005768 "endosome" evidence=IEA;ISO] [GO:0005783 "endoplasmic reticulum" evidence=IEA;ISO] [GO:0005794 "Golgi apparatus" evidence=IEA;ISO] [GO:0005886 "plasma membrane" evidence=ISO] [GO:0005887 "integral component of plasma membrane" evidence=IEA;ISO] [GO:0006486 "protein glycosylation" evidence=IEA;ISO] [GO:0006897 "endocytosis" evidence=IEA;ISO] [GO:0006914 "autophagy" evidence=IEA;ISO] [GO:0007628 "adult walking behavior" evidence=IEA;ISO] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=IEA;ISO] [GO:0016020 "membrane" evidence=ISO] [GO:0016242 "negative regulation of macroautophagy" evidence=IEA;ISO] [GO:0030301 "cholesterol transport" evidence=ISO] [GO:0031982 "vesicle" evidence=IEA;ISO] [GO:0033344 "cholesterol efflux" evidence=IEA;ISO] [GO:0042493 "response to drug" evidence=IEA;ISO] [GO:0042632 "cholesterol homeostasis" evidence=ISO] [GO:0045121 "membrane raft" evidence=IEA;ISO] [GO:0046686 "response to cadmium ion" evidence=IDA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IEA;ISO] [GO:0060548 "negative regulation of cell death" evidence=IMP] [GO:0070062 "extracellular vesicular exosome" evidence=ISO] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IEA;ISO] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IEA;ISO] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 RGD:628693 GO:GO:0005783 GO:GO:0005794 GO:GO:0046686 GO:GO:0048471 GO:GO:0007165 GO:GO:0005576 GO:GO:0005887 GO:GO:0005635 GO:GO:0006914 GO:GO:0045121 GO:GO:0042493 GO:GO:0005768 GO:GO:0006486 GO:GO:0006897 GO:GO:0005764 GO:GO:0015485 GO:GO:0033344 GO:GO:0007628 GO:GO:0031982 GO:GO:0060548 GO:GO:0008158 GO:GO:0071404 GO:GO:0071383 GO:GO:0016242 GeneTree:ENSGT00680000099777 KO:K12385 OrthoDB:EOG7QRQT0 CTD:4864 TreeFam:TF300416 TIGRFAMs:TIGR00917 OMA:ITRAFTM EMBL:CH474073 EMBL:AABR06093698 EMBL:AABR06093699 EMBL:AABR06093700 RefSeq:NP_705888.2 UniGene:Rn.115253 Ensembl:ENSRNOT00000016167 GeneID:266732 KEGG:rno:266732 NextBio:624576 PRO:PR:G3V7K5 Uniprot:G3V7K5) HSP 1 Score: 415.616 bits (1067), Expect = 3.063e-124 Identity = 249/635 (39.21%), Postives = 358/635 (56.38%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGP 626
PF I VFS D E M + CN V+ PCSC DC + C + + + L+ M + ++ ++F G ++ F+ E++ D N SS + + G D+ L FT+WG FC P +IF S++ +G+ +++VTT+P+ELW++P S++R EK++FD+ FGPF+R Q+II+A N S YE G FGP +K E L +L LQ IE I N V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY + KL A WEK FI F+ + +NP ++ I+FT+ERSI DE+++E+ D+ T+ ISY +MF+YI+L+LG S R L++SKI+L I G+LIV+ SV S+GIF +I P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GRI+G+V P+M L+SF+E++ FF GA+S MPAV F+L+AGMA+LIDF +QITCF+S + LDI RQ +N DI +RGP
Sbjct: 201 QAPFTIIPVFS-DLSVLGMEPM---RNATKGCNESVDEVTGPCSCQDCSAVCGPKPQP-PPPPVPWRILGLDAMYVIMWVAYMAFLVLFFGGLLAVWCHRRRYFVSEYTP----IDSNIAFSSNSSDKGEASCCDPLGVAFDDCLRRMFTKWGAFCVRNPTCIIFFSLVFIAACSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNSSVHIYEPYPSGADVPFGPPLNK-EILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDNQVGDDFFVYAD-YHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYN------DTEKLQRAWAWEKEFINFVKNY-KNP----NLTISFTAERSIEDELNRESNSDVFTVLISYAVMFLYISLALGHIQSWNRVLVDSKISLGIAGILIVLSSVTCSLGIFSYIGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSFLGLDIKRQEKNRLDILCCVRGP 805 HSP 2 Score: 194.512 bits (493), Expect = 2.497e-49 Identity = 108/235 (45.96%), Postives = 146/235 (62.13%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C T E K P F ++L FL DNP C K GHAAYS ++ I + D + + A+ FMT+HTILK+S DY +AL+ +R +AS I + ++ RVFPYS+FYVFYEQYLT+ D I +L +S SIF+VT + G EL S++I+ +TI MI N+ G+M+LW ISLNA+SLVNLVM GIS+EFCSH + F +RV R+E L ++GSS+
Sbjct: 977 CVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYSSAVNI-----MGDDTY----IGATYFMTYHTILKTSADYIDALKKARLIASNITETMR----SKGSDYRVFPYSVFYVFYEQYLTIIDDAIFNLSVSLGSIFLVTLVALGCELWSAVIMCLTIAMILVNMFGVMWLWGISLNAVSLVNLVMTCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSV 1198
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:NPC1L1 "NPC1L1 protein" species:9606 "Homo sapiens" [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0008158 EMBL:AC004938 HOVERGEN:HBG003913 UniGene:Hs.567486 GeneID:29881 KEGG:hsa:29881 CTD:29881 HGNC:HGNC:7898 KO:K14461 EMBL:BC143756 RefSeq:XP_005249780.1 Ensembl:ENST00000546276 UCSC:uc011kbw.2 NextBio:35481277 Uniprot:B7ZLE6) HSP 1 Score: 415.231 bits (1066), Expect = 5.030e-124 Identity = 300/958 (31.32%), Postives = 477/958 (49.79%), Query Frame = 0
Query: 43 CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQK----EIEKIETQDNKVLLKDICHTPLTPTSNA---CNIQNLWSYWQDDPKELDKTGYN---DKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAI------------SGMPAVRAFALY--AGMALL-IDFFMQ------ITCFISLMALDIARQRENFWDIFY----------WIR-----GPPTYIEL-------SNRXXXXXXYTLLNNEEETDEEIRFLKK--REKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAK------RELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
CSC DC +SC + + L+ Y + + II L V +++ + ++ D S S + +++ L FF WGT+ A++P+ ++ LSV+ + L G+ + +TTDP+ELW++P S++R EK F D+ FGPF+R QVI+ A N S+++Y+ L K F I L L ++ ++ E Q N + L+DIC+ PL P + + C I +L Y+Q++ L T +T+ D + DHF+ C+ P++ T++ SCM+ G P+ P+ +GG+ Y +A A+++TF +NNY + DP +L A WE+ F+E + + + + F +ERS+ DEI++ T D+ SY+++F+YI+L+LG +S R +++SK TL +GGV +V+ +V A++G F ++ ++L+I +++PFLVL+ G DNIF+ V QR E + +IGR +G V PSMLL S +E+ CFFLGA+ SG+ + F L A +ALL +D Q + C + L Q E F+ WI G P Y S + N ++I++ + + YL D + W T S + N K K LN + C + + + F +YL WFL D P + CPK G AAYS S+ L DG V+AS FM +H LK+S+DY EALR +R+LA+ I + R V + VFPY+I VFYEQYLT+ + + L + + F V+ + G +L S L+ L++IVMI + +G M LW IS NA+SL+NLV A+G+S+EF SH + F ++R++ +++GS++
Sbjct: 254 CSCQDCAASCPAIA---RPQALDSTFYLGQMPGSLVLIIILCSVFAVVTILLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTL----------LGQFFQGWGTWVASWPLTILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRN-ISLQDICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVD-WKDHFLYCANAPLTFKDGTALALSCMADYGAPVFPFLAIGGY--------KGKDYSEAEALIMTFSLNNYP--AGDP----RLAQAKLWEEAFLEEMRAFQR--RMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQGEGLLLGFFQKAYAPFLLHWITRGVVVGAPVYFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSSCCRLYISGPN-KDKFCPSTVNSLNCLKNCMSITMGSVRPSV--EQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVN------LTSDG----QVLASRFMAYHKPLKNSQDYTEALRAARELAANITADL-RKVPGTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAV 1166
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:Q8MI49 "Mutant Niemann-Pick C1" species:9685 "Felis catus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 eggNOG:NOG149152 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF503633 ProteinModelPortal:Q8MI49 STRING:9685.ENSFCAP00000000483 Uniprot:Q8MI49) HSP 1 Score: 414.075 bits (1063), Expect = 1.185e-123 Identity = 246/639 (38.50%), Postives = 357/639 (55.87%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEE-MSYYNTEIEPCNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEF----SIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
PF I +FS +P M N + C+ V+ PCSC DC C + + + L+ M I ++ L+F G F+ E+ S A + ND G + + G + L F++WG+FC P P+IF S+ +G+ ++RVTT+P++LW++P S++R EK++FD FGPF+R Q+II+A + S Y+ G FGP L +L LQ IE I N V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y H + C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY D + ++K H+ WEK FI F+ + +NP ++ I+FT+ERSI DE+++E+ GDI T+ ISY IMF+YI+++LG SC R L++SKI+L I G+LIV+ SV S+GIF ++ P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GR++G+V PSM L+SF+E+ FFLGA+S MPAV F+L+AGMA+LIDF +QITCF+SL+ LDI RQ +N D+ +RG
Sbjct: 200 QAPFTITPIFS-----DLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQP-PPPPVPWRILGLDAMYVIMWITYMAFLLVFFGAFFALWCYRKRYFVSEYTPIDSNIAFSVNANDRGEA--------SCCDALGAAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYPSGSDVPFGPPL-DLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYAD-YHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNY---YNDTERLQKAHV---WEKEFINFVKNY-KNP----NLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVRG 803 HSP 2 Score: 194.126 bits (492), Expect = 4.043e-49 Identity = 106/235 (45.11%), Postives = 144/235 (61.28%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C T E K P F R+L FL DNP C K GHAAYS ++ I + V A+ FMT+HT+L++S D+ +A+R + +AS I + E RVFPYS+FYVFYEQYLT+ DTI +L +S +IF+VT I G +L S++I+ +TI MI N+ G+M+LW ISLNA+SLVNLVM+ GIS+EFCSH + F +R QR+E L ++GSS+
Sbjct: 975 CIRCRPLTQEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGN---------DTGVGATYFMTYHTVLQTSADFTDAMRKANLIASNITKTMGL----EGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAEEALAHMGSSV 1196
BLAST of EMLSAG00000008403 vs. GO
Match: - (symbol:Q8MKD8 "Niemann-Pick C1" species:9685 "Felis catus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF503634 ProteinModelPortal:Q8MKD8 Uniprot:Q8MKD8) HSP 1 Score: 413.305 bits (1061), Expect = 1.705e-123 Identity = 246/639 (38.50%), Postives = 357/639 (55.87%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEE-MSYYNTEIEPCNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEF----SIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
PF I +FS +P M N + C+ V+ PCSC DC C + + + L+ M I ++ L+F G F+ E+ S A + ND G + + G + L F++WG+FC P P+IF S+ +G+ ++RVTT+P++LW++P S++R EK++FD FGPF+R Q+II+A + S Y+ G FGP L +L LQ IE I N V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y H + C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY D + ++K H+ WEK FI F+ + +NP ++ I+FT+ERSI DE+++E+ GDI T+ ISY IMF+YI+++LG SC R L++SKI+L I G+LIV+ SV S+GIF ++ P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GR++G+V PSM L+SF+E+ FFLGA+S MPAV F+L+AGMA+LIDF +QITCF+SL+ LDI RQ +N D+ +RG
Sbjct: 200 QAPFTITPIFS-----DLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQP-PPPPVPWRILGLDAMYVIMWITYMAFLLVFFGAFFALWCYRKRYFVSEYTPIDSNIAFSVNANDRGEA--------SCCDALGAAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYPSGSDVPFGPPL-DLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYAD-YHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNY---YNDTERLQKAHV---WEKEFINFVKNY-KNP----NLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVRG 803 HSP 2 Score: 193.741 bits (491), Expect = 4.377e-49 Identity = 106/235 (45.11%), Postives = 144/235 (61.28%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C T E K P F R+L FL DNP C K GHAAYS ++ I + V A+ FMT+HT+L++S D+ +A+R + +AS I + E RVFPYS+FYVFYEQYLT+ DTI +L +S +IF+VT I G +L S++I+ +TI MI N+ G+M+LW ISLNA+SLVNLVM+ GIS+EFCSH + F +R QR+E L ++GSS+
Sbjct: 975 CIRCRPLTQEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGN---------DTGVGATYFMTYHTVLQTSADFTDAMRKANLIASNITKTMGL----EGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAEEALAHMGSSV 1196
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592809975|gb|GAXK01144593.1| (TSA: Calanus finmarchicus comp58031_c0_seq1 transcribed RNA sequence) HSP 1 Score: 534.258 bits (1375), Expect = 9.802e-167 Identity = 281/513 (54.78%), Postives = 364/513 (70.96%), Query Frame = 0
Query: 132 GEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNL-----STFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQ-------DNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHND-----TYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSC--KRFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
G ++ + FFT WGT A YP+PVI LS+ A+GL TG+ +L VTTDPIELWASP SRSR EKDFFD TF PFYR AQVII AK + + F + D +FGPIF+K F+ +L+LQ++IE++E + D LK +C+ PL+P N CNIQN+ +YWQDD L+K Y+ + N + TYLDHF+ C+ NP + + CMSK G P+ PY+ LGGF+ +S NP+YH+A+AVV++ +++NY+ S+DP ++R L AMEWEK FI+F+H W +N E ++M+IAF SERSI DE+ KET GDI TI ISY+IMFVYIT SLG + C F+IESKITL +GGV+IV+ISV AS+G FGF+ PATLIIFEIIPFLVLA G DNIF+LVQ QR + E+H E++GR+VG+V PSMLL+S +ESTCFFLGA+S MPAVRAFALYAG+AL +DF MQITCF+SL++LD+ RQ N +DI +RG
Sbjct: 1835 GASVENNMTNFFTWWGTLAAKYPLPVIILSIAFAVGLSTGVIYLEVTTDPIELWASPTSRSRVEKDFFDSTFRPFYRTAQVIIHAKEMPEHGVTRFNFTDHLRNQLDFGPIFNK-NFMKEVLKLQQKIEELEFKYKESDGTDQTYNLKKVCNKPLSPEINECNIQNVLAYWQDDEALLEKEKYDPEGNDGNVPRTWTYLDHFLACANNPTLTSQSDKLNIGCMSKWGGPVNPYYCLGGFIPKGSSFPENPEYHKADAVVMSIIVDNYDPKSKDPNDIRGLERAMEWEKVFIDFMHDWEEN-EKPEYMEIAFNSERSIEDELDKETYGDIVTIAISYIIMFVYITFSLGQTSKCTVSMFMIESKITLGLGGVMIVLISVAASIGTFGFVGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQREPRKEYESHAEHVGRVVGEVAPSMLLSSVSESTCFFLGALSDMPAVRAFALYAGVALFVDFLMQITCFVSLLSLDMMRQESNRFDIICCVRG 3367 HSP 2 Score: 169.474 bits (428), Expect = 8.018e-42 Identity = 105/212 (49.53%), Postives = 140/212 (66.04%), Query Frame = 0
Query: 724 FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCXXXXXXXXXXXXXXXXELXXXXXXXXXXXXXXANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNI 935
F + WFL+ NPG CP AGHAAY S+ + + V +SN M FH+ILK+SKDYY AL +R+L + +N N T+ +FPYS+FYVFYEQYLTMW DT++ L IS +IF+VTF+ GF+L+SS I L+ IV+I NL G+MY W+I+LNA+SLVNLVMA+GIS+EFCSH + F G +R +R+ L N+
Sbjct: 404 FGETIEWFLKANPGEQCPSAGHAAYGASVKLANNGGSNS-------VRSSNMMAFHSILKTSKDYYMALARARELTDNVMEFVN-NGTDPEDHVNIFPYSVFYVFYEQYLTMWRDTLQQLSISLAAIFLVTFVLMGFDLVSSCINLLIIVLIVLNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHMTRAFSVNIGKDRTERALNVLTNM 1015 HSP 3 Score: 36.965 bits (84), Expect = 3.921e-1 Identity = 16/56 (28.57%), Postives = 28/56 (50.00%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVN-GKSPCSCTDCESSCASQI 56
++PFQI++ + + + + +Y+N CN+ G S C C DC +C I
Sbjct: 3701 YSPFQINYEYGSSQTSG--DNHTYHNPSATACNLPAQPGMSACGCADCPQACTVNI 3862
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592765108|gb|GAXK01189460.1| (TSA: Calanus finmarchicus comp620364_c3_seq4 transcribed RNA sequence) HSP 1 Score: 508.449 bits (1308), Expect = 5.029e-162 Identity = 274/520 (52.69%), Postives = 359/520 (69.04%), Query Frame = 0
Query: 125 INSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAK-----NLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIE-------TQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHND-----TYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCK--RFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+N + G L+ + FT WGT ATYP+PVI +S MA+ L TGI +L+VTT+PIELWASP SRSR EKDFFD F PFYR +QVII AK N++ F + D E GPIF K FL +L+LQK+IE +E D K LK +C+ PL+P CNIQN+ +YWQDD + LD Y+ + D YLDHF+ C+ NP + + CM++ G P++PY+ LGGF+ + S NP YHQA+AVV+T ++NNY+ S + ++++ L AM WEKTFIEF+ +W + E +MDIAF SERSI DE+ KET GDI TI +SY+IMFVYIT +LG SC F+IESK+TL +GGVLIV++SV AS+G+F F+ PATLIIFEIIPFLVLA G DNIF+LVQ QR + E+H E++GRIVG+V PSML++S +ESTCFFLGA+S MPAV+AFALYAGMA+++DF MQITCF+SL++LDI+R+ +DI ++G
Sbjct: 1323 LNFLDRLGAKLETKMTRLFTWWGTVAATYPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQK-TFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEW-EEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAEHVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKG 2876 HSP 2 Score: 38.1206 bits (87), Expect = 1.905e-1 Identity = 16/56 (28.57%), Postives = 28/56 (50.00%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVN-GKSPCSCTDCESSCASQI 56
++PFQI++ + P+ +Y+N + PC + G + C C DC +C I
Sbjct: 879 YSPFQINYDYGS---GHTPDNYTYHNPPVTPCQMSPQPGVAACGCADCPQACKINI 1037
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592765110|gb|GAXK01189458.1| (TSA: Calanus finmarchicus comp620364_c3_seq2 transcribed RNA sequence) HSP 1 Score: 508.449 bits (1308), Expect = 1.735e-161 Identity = 274/520 (52.69%), Postives = 359/520 (69.04%), Query Frame = 0
Query: 125 INSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAK-----NLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIE-------TQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHND-----TYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCK--RFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+N + G L+ + FT WGT ATYP+PVI +S MA+ L TGI +L+VTT+PIELWASP SRSR EKDFFD F PFYR +QVII AK N++ F + D E GPIF K FL +L+LQK+IE +E D K LK +C+ PL+P CNIQN+ +YWQDD + LD Y+ + D YLDHF+ C+ NP + + CM++ G P++PY+ LGGF+ + S NP YHQA+AVV+T ++NNY+ S + ++++ L AM WEKTFIEF+ +W + E +MDIAF SERSI DE+ KET GDI TI +SY+IMFVYIT +LG SC F+IESK+TL +GGVLIV++SV AS+G+F F+ PATLIIFEIIPFLVLA G DNIF+LVQ QR + E+H E++GRIVG+V PSML++S +ESTCFFLGA+S MPAV+AFALYAGMA+++DF MQITCF+SL++LDI+R+ +DI ++G
Sbjct: 1323 LNFLDRLGAKLETKMTRLFTWWGTVAATYPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQK-TFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEW-EEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAEHVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKG 2876 HSP 2 Score: 38.1206 bits (87), Expect = 1.793e-1 Identity = 16/56 (28.57%), Postives = 28/56 (50.00%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVN-GKSPCSCTDCESSCASQI 56
++PFQI++ + P+ +Y+N + PC + G + C C DC +C I
Sbjct: 879 YSPFQINYDYGS---GHTPDNYTYHNPPVTPCQMSPQPGVAACGCADCPQACKINI 1037
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592765109|gb|GAXK01189459.1| (TSA: Calanus finmarchicus comp620364_c3_seq3 transcribed RNA sequence) HSP 1 Score: 506.523 bits (1303), Expect = 2.366e-161 Identity = 273/520 (52.50%), Postives = 359/520 (69.04%), Query Frame = 0
Query: 125 INSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAK-----NLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIE-------TQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHND-----TYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCK--RFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+N + G L+ + FT WGT AT+P+PVI +S MA+ L TGI +L+VTT+PIELWASP SRSR EKDFFD F PFYR +QVII AK N++ F + D E GPIF K FL +L+LQK+IE +E D K LK +C+ PL+P CNIQN+ +YWQDD + LD Y+ + D YLDHF+ C+ NP + + CM++ G P++PY+ LGGF+ + S NP YHQA+AVV+T ++NNY+ S + ++++ L AM WEKTFIEF+ +W + E +MDIAF SERSI DE+ KET GDI TI +SY+IMFVYIT +LG SC F+IESK+TL +GGVLIV++SV AS+G+F F+ PATLIIFEIIPFLVLA G DNIF+LVQ QR + E+H E++GRIVG+V PSML++S +ESTCFFLGA+S MPAV+AFALYAGMA+++DF MQITCF+SL++LDI+R+ +DI ++G
Sbjct: 1329 LNFLDRLGAKLETKMTRLFTWWGTVAATHPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQK-TFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEW-EEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAEHVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKG 2882 HSP 2 Score: 38.1206 bits (87), Expect = 1.906e-1 Identity = 16/56 (28.57%), Postives = 28/56 (50.00%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVN-GKSPCSCTDCESSCASQI 56
++PFQI++ + P+ +Y+N + PC + G + C C DC +C I
Sbjct: 885 YSPFQINYDYGS---GHTPDNYTYHNPPVTPCQMSPQPGVAACGCADCPQACKINI 1043
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592765111|gb|GAXK01189457.1| (TSA: Calanus finmarchicus comp620364_c3_seq1 transcribed RNA sequence) HSP 1 Score: 506.523 bits (1303), Expect = 9.717e-161 Identity = 273/520 (52.50%), Postives = 359/520 (69.04%), Query Frame = 0
Query: 125 INSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAK-----NLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIE-------TQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHND-----TYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCK--RFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+N + G L+ + FT WGT AT+P+PVI +S MA+ L TGI +L+VTT+PIELWASP SRSR EKDFFD F PFYR +QVII AK N++ F + D E GPIF K FL +L+LQK+IE +E D K LK +C+ PL+P CNIQN+ +YWQDD + LD Y+ + D YLDHF+ C+ NP + + CM++ G P++PY+ LGGF+ + S NP YHQA+AVV+T ++NNY+ S + ++++ L AM WEKTFIEF+ +W + E +MDIAF SERSI DE+ KET GDI TI +SY+IMFVYIT +LG SC F+IESK+TL +GGVLIV++SV AS+G+F F+ PATLIIFEIIPFLVLA G DNIF+LVQ QR + E+H E++GRIVG+V PSML++S +ESTCFFLGA+S MPAV+AFALYAGMA+++DF MQITCF+SL++LDI+R+ +DI ++G
Sbjct: 1329 LNFLDRLGAKLETKMTRLFTWWGTVAATHPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQK-TFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEW-EEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAEHVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKG 2882 HSP 2 Score: 38.1206 bits (87), Expect = 1.871e-1 Identity = 16/56 (28.57%), Postives = 28/56 (50.00%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVN-GKSPCSCTDCESSCASQI 56
++PFQI++ + P+ +Y+N + PC + G + C C DC +C I
Sbjct: 885 YSPFQINYDYGS---GHTPDNYTYHNPPVTPCQMSPQPGVAACGCADCPQACKINI 1043
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592794335|gb|GAXK01160233.1| (TSA: Calanus finmarchicus comp142827_c0_seq2 transcribed RNA sequence) HSP 1 Score: 496.123 bits (1276), Expect = 3.379e-153 Identity = 291/652 (44.63%), Postives = 403/652 (61.81%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAXXXXXXXXXXXXXXXTSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAK-----NLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKI-----ETQDNKVL-----LKDICHTPLTPTSNACNIQNLWSYWQDDPKELDK--TGYNDKTNHNDTYLDHFILCSRNP--VSQA------AETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGD--NTSCKRFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+ PF I++ F + Y++ E+ C G S C C +C ++C+ + + N + Y F + + + ++ + + S FSI + + T K N + +A E FFT WG F A +PV V+ +S+ +A GLC G+ L++TTDPIELWASP SRSR EKDFFD F PFYR + VIIKA + F + D +G+ EFG +F+K +FL L+LQ++IE I ET+ N+ + L IC++PL+P + CNI N W+YW DD LDK +D N TYLDHF+ C +NP VSQ + + C++K G P+ PY+VLGGF+ + +P Y ++ A+V+ +INN++ +S ++++ L AM WE+ F+EF+ W++N E +++D+AFTSERS+ DE+ +ET GD+ TI +SY+IMF+YITLSLG S F+IESKITL + GV+IV++SV AS+GIF PATLIIFEIIPFLVLA G DNIF+LVQ QR TET +E +GR+VG+V PSMLL+S TESTCFFLGA+SGMPAVRAFA+YAGMALLIDF MQ+T F++LM+LD+ARQR N +DI IRG
Sbjct: 1705 YAPFTINYEFD-TDDDISITDFEYHSPEVISCQDTAPGYSTGCGCANCPAACSGSGVPEFNREDDKPFY-----DFKLGGLDGLSVIMGLVFSVGSVLFIGFSIVCVPSVIPVTTKPKIGPKARTNLVNDAIEK-------FFTWWGKFAARHPVLVLVISLTIAFGLCCGVVKLKITTDPIELWASPTSRSRVEKDFFDTEFRPFYRTSLVIIKANENPSAGIEKFNFTDAYGKEYEFGAMFNK-KFLKEALKLQQKIENITFQYEETEGNETVEHTYDLTRICNSPLSPLNTNCNINNAWAYWHDDESLLDKEFKPSSDSVGRNLTYLDHFLDCVKNPSMVSQQDTHTDLGDGNGGIGCLAKWGGPVNPYYVLGGFIPEGTTFPESPDYAKSQAIVMQIIINNFDPHSEKEEDVKGLERAMAWEEKFVEFMKDWVEN-EMPEYIDVAFTSERSVEDELDRETYGDVATIAVSYIIMFIYITLSLGQYGKFSLSGFMIESKITLGLFGVMIVLLSVFASIGIFAVAGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQRDKKRPTETDEEQVGRVVGEVAPSMLLSSLTESTCFFLGALSGMPAVRAFAMYAGMALLIDFLMQVTSFVALMSLDMARQRNNKFDILCCIRG 3615 HSP 2 Score: 174.866 bits (442), Expect = 1.784e-43 Identity = 113/236 (47.88%), Postives = 159/236 (67.37%), Query Frame = 0
Query: 704 CQKCPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKK--RAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCXXXXXXXXXXXXXXXXELXXXXXXXXXXXXXXANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNI 935
C C + D A D + P + F +S FLE NPG CPKAGH A++ ++ + + A + + +Y+V +SN M FHTIL++S+DYY AL+ +R+L I IN N T E +K VFPYSIFYVFYEQYLTMW DT+ S+ IS ++IF+VTF+ GF+L S+ IIL I++I NL +MY WNI+LNA+SLVNLVMA+GIS+EFCSH +YF +R++ + +++ +
Sbjct: 472 CVGCLD-DSAYDNHDFRPDSEEFSETISLFLEQNPGEFCPKAGHGAFADAVKLTQLESATANLNESLKYNVASSNMMAFHTILRTSEDYYTALKRARELTDSITEMINANRTEE-EKVNVFPYSIFYVFYEQYLTMWKDTLISVGISLVTIFVVTFLLMGFDLRSATIILFVIILILINLGALMYWWNITLNAVSLVNLVMAVGISVEFCSHITRYFATHSHQDRIENARNSVIKM 1173
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592794336|gb|GAXK01160232.1| (TSA: Calanus finmarchicus comp142827_c0_seq1 transcribed RNA sequence) HSP 1 Score: 496.123 bits (1276), Expect = 3.812e-153 Identity = 291/652 (44.63%), Postives = 403/652 (61.81%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAXXXXXXXXXXXXXXXTSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAK-----NLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKI-----ETQDNKVL-----LKDICHTPLTPTSNACNIQNLWSYWQDDPKELDK--TGYNDKTNHNDTYLDHFILCSRNP--VSQA------AETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGD--NTSCKRFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+ PF I++ F + Y++ E+ C G S C C +C ++C+ + + N + Y F + + + ++ + + S FSI + + T K N + +A E FFT WG F A +PV V+ +S+ +A GLC G+ L++TTDPIELWASP SRSR EKDFFD F PFYR + VIIKA + F + D +G+ EFG +F+K +FL L+LQ++IE I ET+ N+ + L IC++PL+P + CNI N W+YW DD LDK +D N TYLDHF+ C +NP VSQ + + C++K G P+ PY+VLGGF+ + +P Y ++ A+V+ +INN++ +S ++++ L AM WE+ F+EF+ W++N E +++D+AFTSERS+ DE+ +ET GD+ TI +SY+IMF+YITLSLG S F+IESKITL + GV+IV++SV AS+GIF PATLIIFEIIPFLVLA G DNIF+LVQ QR TET +E +GR+VG+V PSMLL+S TESTCFFLGA+SGMPAVRAFA+YAGMALLIDF MQ+T F++LM+LD+ARQR N +DI IRG
Sbjct: 1725 YAPFTINYEFD-TDDDISITDFEYHSPEVISCQDTAPGYSTGCGCANCPAACSGSGVPEFNREDDKPFY-----DFKLGGLDGLSVIMGLVFSVGSVLFIGFSIVCVPSVIPVTTKPKIGPKARTNLVNDAIEK-------FFTWWGKFAARHPVLVLVISLTIAFGLCCGVVKLKITTDPIELWASPTSRSRVEKDFFDTEFRPFYRTSLVIIKANENPSAGIEKFNFTDAYGKEYEFGAMFNK-KFLKEALKLQQKIENITFQYEETEGNETVEHTYDLTRICNSPLSPLNTNCNINNAWAYWHDDESLLDKEFKPSSDSVGRNLTYLDHFLDCVKNPSMVSQQDTHTDLGDGNGGIGCLAKWGGPVNPYYVLGGFIPEGTTFPESPDYAKSQAIVMQIIINNFDPHSEKEEDVKGLERAMAWEEKFVEFMKDWVEN-EMPEYIDVAFTSERSVEDELDRETYGDVATIAVSYIIMFIYITLSLGQYGKFSLSGFMIESKITLGLFGVMIVLLSVFASIGIFAVAGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQRDKKRPTETDEEQVGRVVGEVAPSMLLSSLTESTCFFLGALSGMPAVRAFAMYAGMALLIDFLMQVTSFVALMSLDMARQRNNKFDILCCIRG 3635 HSP 2 Score: 174.866 bits (442), Expect = 1.793e-43 Identity = 113/236 (47.88%), Postives = 159/236 (67.37%), Query Frame = 0
Query: 704 CQKCPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKK--RAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCXXXXXXXXXXXXXXXXELXXXXXXXXXXXXXXANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNI 935
C C + D A D + P + F +S FLE NPG CPKAGH A++ ++ + + A + + +Y+V +SN M FHTIL++S+DYY AL+ +R+L I IN N T E +K VFPYSIFYVFYEQYLTMW DT+ S+ IS ++IF+VTF+ GF+L S+ IIL I++I NL +MY WNI+LNA+SLVNLVMA+GIS+EFCSH +YF +R++ + +++ +
Sbjct: 492 CVGCLD-DSAYDNHDFRPDSEEFSETISLFLEQNPGEFCPKAGHGAFADAVKLTQLESATANLNESLKYNVASSNMMAFHTILRTSEDYYTALKRARELTDSITEMINANRTEE-EKVNVFPYSIFYVFYEQYLTMWKDTLISVGISLVTIFVVTFLLMGFDLRSATIILFVIILILINLGALMYWWNITLNAVSLVNLVMAVGISVEFCSHITRYFATHSHQDRIENARNSVIKM 1193
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592810949|gb|GAXK01143619.1| (TSA: Calanus finmarchicus comp525863_c1_seq1 transcribed RNA sequence) HSP 1 Score: 177.563 bits (449), Expect = 5.776e-45 Identity = 113/232 (48.71%), Postives = 153/232 (65.95%), Query Frame = 0
Query: 704 CQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCXXXXXXXXXXXXXXXXELXXXXXXXXXXXXXXANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNI 935
C C N+ ++ GP F + + WFL NP CP GHAAY +S+ LD D V +SN M FHTILK+S+D+Y AL +R+LA I A+N N T ++ +FPYS+FYVFYEQYLTMW DT+KSL IS +IF+VTF+F GF+++SS I L+ I++I N+ G+MY WNI+LNAISLVNLVM +GIS+EFC H+ + F G +RV+R+ L ++
Sbjct: 1413 CLPC-NTTFLERGDRPGPDQFSQTIDWFLAANPSDKCPSGGHAAYGESVR------LDDDNGVRV-VTSSNMMAFHTILKTSEDFYMALSRARELADSIMQAVN-NGTEAEKQVNIFPYSVFYVFYEQYLTMWRDTLKSLAISITAIFLVTFVFMGFDIVSSFINLLIIILIVLNMGGLMYWWNITLNAISLVNLVMTVGISVEFCCHTTRAFSVNVGRDRVERATAILTSM 2081
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592765798|gb|GAXK01188770.1| (TSA: Calanus finmarchicus comp326528_c2_seq1 transcribed RNA sequence) HSP 1 Score: 86.2705 bits (212), Expect = 4.121e-16 Identity = 64/200 (32.00%), Postives = 102/200 (51.00%), Query Frame = 0
Query: 419 KHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLG--DNTSCKRFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYG-PESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQREN 615
K ++I R + + + + DI + + YLI+FVY+ L LG D K FL I GV + II FGF A ++PFL+L G D++F++VQ E +++ ++ IG + ++ +TS T F +GA S +PA+R+F +YA + ++I FF Q T F++L+ALD R N
Sbjct: 1539 KGVEIFVNIHRMLFESMEGQVFKDIGMLLLGYLIVFVYVLLMLGKCDCVEQKVFLSIGGI----LGVAMGIIVSYGLCSAFGFFYSAA----HTVMPFLLLGIGIDDMFVIVQCLSTLSEKEKSKSVEDRIGATMAHAGVAITITSVTNFIAFGIGASSSLPALRSFCVYASLGIIIIFFFQTTWFVALLALDEYRVEAN 2114 HSP 2 Score: 38.1206 bits (87), Expect = 2.233e-1 Identity = 24/78 (30.77%), Postives = 34/78 (43.59%), Query Frame = 0
Query: 145 RW-GTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLST 221
RW G A P IFLS + + G+ +D LW S+ R ++ + F R QVI KA+N+ T
Sbjct: 2895 RWHGRLVARQPALFIFLSFIATIICGLGLIGFYEESDMTALWVPKGSKLRNNVEWVQQNFPQQLRFNQVIFKAENVLT 3128
BLAST of EMLSAG00000008403 vs. C. finmarchicus
Match: gi|592822654|gb|GAXK01131914.1| (TSA: Calanus finmarchicus comp251849_c0_seq1 transcribed RNA sequence) HSP 1 Score: 83.9593 bits (206), Expect = 1.639e-15 Identity = 116/492 (23.58%), Postives = 204/492 (41.46%), Query Frame = 0
Query: 145 RWGTFCATYPVPVIFLSVLMALGLCTG--IFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHND--TYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITXXXXXXXXXXXXXXXXXXXFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENF-----WDIFYWIRGPP 627
RWG A +P + +S L+ G+ +G + W + + + LW +S +K + E F R +++ +N+ T F E + I + + N + L+D+C P + + L GY K N+ + + D +L A T M +S G P G FLSG A + A A++ +L+ + +++P E + A +WE FI+ I P K ++I +ERS DEI +I + ++++F+YI + LG+ ++ + S + + G+ + F D I IIPFL+L G D++F++VQ E+ ++ + + + S+ +TSFT++ FF+GA + MP +R F +AG ++ FF IT F++ + LD R+ W+ W R P
Sbjct: 1339 RWGQIVARWPWTTVLVS-LVVCGIFSGGMLLWYQEKDEEV-LWTPYKSPFIAQKAWISEHFPRDRRFENLVMVGENVLTADTVRYFVE-------------------IDTRIREYRSSQN-LTLEDLCLKYPDPVNGGFG----------ECLTLGVLGYFSKMNNQELSSLTDKQVL--------AFITEMYKS----EGTP-------GQFLSGVAFSL-DGNVTGAKALINIWLLKDD---AKNPFESNED--AQDWENGFIDAIIT-APPPNMPKGLEIFCLAERSYNDEIDYVVNSNIPLLMAGFVLLFIYIMVVLGNFNWIEQRALLSIAGMVVIGLALGASFGLCFYFGISFND------ICPIIPFLLLGIGVDDMFVIVQCLDNLENIEGESPEDKVAKAMKHAGVSITVTSFTDAAAFFIGATTSMPILRGFCYFAGTGVIFLFFFAITFFVACLVLDERRKTSQINKRPNWNPSPWTRMQP 2622
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000008403 (pep:novel supercontig:LSalAtl2s:LSalAtl2s513:547002:563743:1 gene:EMLSAG00000008403 transcript:EMLSAT00000008403 description:"maker-LSalAtl2s513-augustus-gene-5.4") HSP 1 Score: 2032.3 bits (5264), Expect = 0.000e+0 Identity = 990/990 (100.00%), Postives = 990/990 (100.00%), Query Frame = 0
Query: 1 MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPTYIELSNRXXXXXXYTLLNNEEETDEEIRFLKKREKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSFCRFFRPQHFVHISPIKSRALSIATITKNNKQNINATPITEK 990
MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPTYIELSNRXXXXXXYTLLNNEEETDEEIRFLKKREKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSFCRFFRPQHFVHISPIKSRALSIATITKNNKQNINATPITEK
Sbjct: 1 MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPTYIELSNRXXXXXXYTLLNNEEETDEEIRFLKKREKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSFCRFFRPQHFVHISPIKSRALSIATITKNNKQNINATPITEK 990
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000001950 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1345:18618:29195:1 gene:EMLSAG00000001950 transcript:EMLSAT00000001950 description:"maker-LSalAtl2s1345-snap-gene-0.7") HSP 1 Score: 637.106 bits (1642), Expect = 0.000e+0 Identity = 338/654 (51.68%), Postives = 428/654 (65.44%), Query Frame = 0
Query: 3 TPFQIDFVFSGD-KXASIPEEMSYYNTEIEPCNIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDT----------GSSKTFFSR--------------------TINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
TPFQID+VFSG+ + IPE + +YNT +E C++ VNG PCSC DCES+C + Y ++ + F MAIIF++G +IF+ +VI S+ +K S D +D+ GS ++ S+ ++N I+ AG DL+ WL+ FFT WGTFCA YP+PVI +S+ +A+GLCTGIFWL VTTDPIELWASP SRSR E+DFFD+TF PFYRI QVI+KAKNLS+F+Y+D GETK FGPIFHK EFL PLL LQK NI+N+ KT N L P+S GGIP++PY++LGGF+ N NP YH+A+AVVI+ +INNY+ S +P+E++KL A+EWEK + +MDIAFTSERSI DE++KET GDI+TI +SY+IMF+YIT SLG+NT+ KRF++ESKITL +GGV+IV++SV AS+GIFGFID PATLIIFEIIPFLVLA GXDNIF++VQ QR +TETH E++GRIVG+V PSMLLTS TESTCFFLGAIS MPAVRAFALYAGMALLIDF MQ+TCFISL++LD+ARQ +N++DI +RG
Sbjct: 197 TPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEPCSCADCESACEPPHFEETQVGF-YIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQK-----------------------------NIENI------------------KTKENGITLKDICHAPLEPISD-------------GGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY---------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRG 774 HSP 2 Score: 318.161 bits (814), Expect = 1.985e-91 Identity = 155/244 (63.52%), Postives = 194/244 (79.51%), Query Frame = 0
Query: 688 DSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEIT 931
+SV++K ++KR + C KCPNSDDA D + GP AFRRY+ WFLEDNPG CPKAGHAAYS+S+ +K D + F +Y+VIASNFMTFHTILK+ KDYYEALR +R+L+SEIEN+IN N+T+++Q +VFPYSIFYVFYEQYLTMW DTI SL +SF+SI IVTFI TGF+ ++S+II+V I MI NLMGMMY WNISLNA+SLVNLVMA+GIS+EFCSH K F H ++ R++ +
Sbjct: 1016 NSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000004370 (pep:novel supercontig:LSalAtl2s:LSalAtl2s22:157610:161978:1 gene:EMLSAG00000004370 transcript:EMLSAT00000004370 description:"maker-LSalAtl2s22-snap-gene-1.32") HSP 1 Score: 389.423 bits (999), Expect = 9.162e-119 Identity = 210/494 (42.51%), Postives = 315/494 (63.77%), Query Frame = 0
Query: 138 WLII--FFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKN---LSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQAN--AVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQ-NPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQR--YGPESTETHQE-YIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIF 620
WL+ FF + G FC+ Y V V+ + ++ + L +G+FWL+VT++PIELW+S SRSR+E DFF+E F PF+R + +II N L F+Y +L+G+ F IF + E +L+LQKEIEKI T+D K+ L+D+C+ PL P +C +Q++W+YWQ + ND+ H DTYLDH C NP + + T+M QSC+SKG +P++ FV+GGF + + + + + AN A+++TFL+ N+ + R + A++WEK+F+ KWI+ N EN +DIAF +E SI D I + GD+ + ISY +MFVY++ +L D + K F ITLAI G+ +V+ S+ ++ G+FGFI AT+IIFEI+PFLVLA G DNIF+LV A+R E E + IG + ++ P+ML+++ T++ F+LG +S MPAV FALYAG +LLI+F QIT FI++++LD+ R + D+F
Sbjct: 106 WLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQ-EMFYQVLKLQKEIEKIITED-KITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDR-GHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEK-------AIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLF 581 HSP 2 Score: 90.1225 bits (222), Expect = 1.548e-18 Identity = 50/140 (35.71%), Postives = 87/140 (62.14%), Query Frame = 0
Query: 770 VIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFC 909
++ SNFM FHT+L++S D+ +A+ +R L+ + A N+T+ FPYSIF+V+YEQYL+M DT+ S+ +++ ++ + +G +++ L + + I ++ G + + I LNAI VNL++A GIS+E C
Sbjct: 754 ILFSNFMAFHTVLRTSNDFVQAIESTRILSDKF--ARENNITS-------FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC 883
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000003602 (pep:novel supercontig:LSalAtl2s:LSalAtl2s197:152115:159124:1 gene:EMLSAG00000003602 transcript:EMLSAT00000003602 description:"maker-LSalAtl2s197-snap-gene-1.29") HSP 1 Score: 92.8189 bits (229), Expect = 2.346e-19 Identity = 65/223 (29.15%), Postives = 109/223 (48.88%), Query Frame = 0
Query: 400 WEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRA----QRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWD 618
WEK+ E + + E++ ++ + S E D+ YLI+FVYI +LG+ + +E K LA+ G+ V + +SVGIF + AT + I+PF++L G D++F++VQ + Q E YIG I+ ++ +TS T+ F +G S +PA+R F LY+ + +F +T F+ +D AR+ E+ D
Sbjct: 249 WEKSVKEHVFNYSFGDESS-NLSVTLFSSSIFRAEFQNGMENDVQLFIFGYLIVFVYIIFNLGEMNT-----LEHKFYLAVVGIACVGMGYASSVGIFQLLSVYATPM-NSILPFMLLGIGIDDMFVIVQASKNVKQNDDEEGENKMDSYIGNIMKSAGXAITVTSLTDILAFGIGGFSQLPALRNFCLYSSAGIFFVYFYIMTFFLGWFVID-ARRVESHRD 463 HSP 2 Score: 53.9138 bits (128), Expect = 1.971e-7 Identity = 38/191 (19.90%), Postives = 96/191 (50.26%), Query Frame = 0
Query: 764 GFTEYDVIASNFMTFHTILKSSK--DYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSFCRF 952
G T DV S F+ + +K ++ D ++++ Q+ +IE N +FP++ Y + + +++ ++ +++FI ++S+ +L++I++ ++ G MY W +S++ S V L +++G+++++ +H ++H +R ++ + +L +G ++ S G ++F F
Sbjct: 638 GDTTEDVKLSAFVLYFQHIKKTRVQDQIQSMKKIYQIGEKIEGERN---------GLIFPHATQYSNLITLDIILSELTRNILLALMTVFIAALFLLA-XALTSIYVLLSILLSIIDVTGYMYFWGVSIDTASAVLLTVSLGLAVDYSAHIAHGYIHSSKSSRGEKVKDSLTKVGPAVL--SGGISTFLAF 816
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000007725 (pep:novel supercontig:LSalAtl2s:LSalAtl2s44:25674:28922:-1 gene:EMLSAG00000007725 transcript:EMLSAT00000007725 description:"maker-LSalAtl2s44-augustus-gene-0.13") HSP 1 Score: 88.9669 bits (219), Expect = 3.339e-18 Identity = 66/243 (27.16%), Postives = 116/243 (47.74%), Query Frame = 0
Query: 376 FLINNYNQYSRDPQEMRKLHL---AMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGI---FGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGP-ESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIAR 611
FL N + + P E + + + ME+EK ++ + PE K I+ RS D GD+ + I Y I+F Y+ L LG K + + LAI G++ V+ + S+GI GF P + I+PFL+L G D++F+++Q P E + + G + ++ +TS T+ F +G S +PA+R+F +++ + + ++ Q+T F++ M D R
Sbjct: 329 FLKMNIAEARKSPVEGQGVIVDKKTMEFEKEMLDILLNDTGLPEGLK---ISPHVSRSFFDIAGPTILGDVKILGIGYSIVFFYVLLMLG-----KFDWVGXRXYLAIAGIISVVFGIVFSIGICSAMGFFWSP----MHSILPFLLLGIGIDDMFIIIQCWNTLNPYEKASSSVDKFGYTMRHAGVAITVTSLTDIVAFGIGGTSXLPALRSFCIFSAVGIAAIYYFQVTFFVAWMVFDEKR 559 HSP 2 Score: 68.5514 bits (166), Expect = 6.265e-12 Identity = 50/203 (24.63%), Postives = 106/203 (52.22%), Query Frame = 0
Query: 756 KRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIE-NAINR-----NVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSFCRF 952
KR +L +G ++D S+ F++ S Y+ + S+I+ +A+NR N N R+FP S Y +E + + K++ +F+++FI+T+I ++S ++L +++ ++ G+M+ W ++++ +S L+++IG+ +++ +H FL + +R QR L NIG ++ + G ++F F
Sbjct: 739 KRNFLTVNGTADFDCGKSSTGFFNS--NESIWYFNFNYKVLESDSKIKISAMNRIKDILNSANLTSSGRIFPLSQGYSMWETDEIIGYELYKNIIFAFVAVFIMTWIVIS-NFVASFLVLFAVMLTVLDVSGIMHFWGLTIDTVSCNFLIISIGLCVDYSTHVAHRFLIEAEGSRDQRIVKALTNIGPAV--MNGGISTFLAF 936
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000010537 (pep:novel supercontig:LSalAtl2s:LSalAtl2s6:1415448:1420769:-1 gene:EMLSAG00000010537 transcript:EMLSAT00000010537 description:"maker-LSalAtl2s6-augustus-gene-13.12") HSP 1 Score: 72.7886 bits (177), Expect = 4.108e-13 Identity = 57/240 (23.75%), Postives = 108/240 (45.00%), Query Frame = 0
Query: 383 QYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLS--LGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIF 620
Y D E + +L + WEK F++ + + P ++I + E+ +T+ I+ +IM V+ +S + D T +SK + G+ I+ A G ++ + F PFL+L G D+ F+++ +R S + E +GR + S+ +TS T+ F G ++ P VR F LY G+++ +F +T F +++A+ ++ N +F
Sbjct: 215 SYFLDVSEEWRDNLGLRWEKKFLDALRE--IGPYFAPDLEIGMFVSNTPAWEMEASKNSVTSTLCINVVIMVVFSLVSCLMSDAT-------KSKPLVGFAGLFSATIATIAGFGFACYVGVEFISLNFAA-PFLLLGIGVDDTFVILSSWRR--SSSNLSIPERMGRCYSEAAVSITVTSLTDFFSFMAGVVTPFPCVRIFCLYTGISVAFIYFWHLTLFGAILAVSGRAEKNNLHGMF 442 HSP 2 Score: 61.6178 bits (148), Expect = 8.439e-10 Identity = 34/144 (23.61%), Postives = 75/144 (52.08%), Query Frame = 0
Query: 794 MSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSH-SVKYFLHKEGVNRVQRSEITLVNIG 936
M + + +E+ + N+ T + + PY +++ +QYL + T++ + ++ + + I++F L+ S + +I+ I ++G M W + L+ ++L+NL+M IG S++F +H Y E + +R +L +G
Sbjct: 674 MEQSMVAELRDICNQFSTPDISISVFHPY---FIYIDQYLAIAPQTVQCILVTSLVMMIISFFLIP-SLVCSFWVAFSIISIELGVIGYMTWWGVRLDGVALINLIMCIGFSVDFSAHICYHYITDTESSSPDERIRSSLYGLG 813
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000008727 (pep:novel supercontig:LSalAtl2s:LSalAtl2s542:206164:232722:1 gene:EMLSAG00000008727 transcript:EMLSAT00000008727 description:"maker-LSalAtl2s542-augustus-gene-2.8") HSP 1 Score: 68.1662 bits (165), Expect = 8.009e-12 Identity = 108/499 (21.64%), Postives = 193/499 (38.68%), Query Frame = 0
Query: 133 EDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMK-QSCMSKGGIPI-------KPY---FVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDIN--TITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVG---DVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQREN 615
E +D+ L F++ G +P + + +L+ TG L +DP L++ S E+ + F Y + +++ ++ L +K+ G I +++ +EIE + I+N + KE D+ + K N D H C RN + + + +S K P+ + Y F GG + N S + AV + + +N+ Q S+D + K WE F+ + ++ ++ +A S ++ E+ T I + I +I F IT + D ++SK L + GV+ I++ S G + P I PFL+L G D+ F+++ +R T H+ R+ D S+ +TS T+ F++G I+ P+VR F LY G + + IT F MA+ ++ N
Sbjct: 7 EFIDDSLKFIFSKVGIIVGKHPGYFVIIPLLLTALAATGFQRLHFQSDPEYLFSPSDGESHYERKVLETYFNTNYSDFE---PSRSSRVGRFGKLIISSKDNGSILR--------MKIWEEIESLNFL----------------------IENFEVF---SLKECDEVKSSMKLNFKDLCASHQGKCWRNKILDLGKHITEIESKEIKLTFPLWFDPETFQGYTFNFFFGGVILRNDSTIKS-----VTAVSLFYFLNS--QTSKDIERGAK------WEGMFLATVE-----AQSFSYIKVARFSSLTLEVELENNTNSVIPFFALNIGIMIAFCIITCMMTD-------WVKSKPLLGLFGVISAIMAXLFSFGFIIYCGVPFIGINLAA-PFLMLGIGIDDTFVMLGSWRR-----TSVHETVPARLAQTYRDAAISITITSITDMLSFWIGIITPFPSVRIFCLYTGACVAFTYLWHITFFGGCMAIAGYAEKSN 438 HSP 2 Score: 60.077 bits (144), Expect = 2.815e-9 Identity = 45/177 (25.42%), Postives = 85/177 (48.02%), Query Frame = 0
Query: 756 KRAYLDQDGFTEY-----------DVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVF-PYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKE 920
K YL GFT Y +IAS F+ T + ++ D ++ E+ N VF PY +++++Q+L + TI+ + ++ + ++ IF + SL + +I+ I ++G M LW + L++IS++NL+M IG S++F +H +++ E
Sbjct: 627 KEVYLGS-GFTHYVKDVHFSTDNKSIIASRFLIQGTKIYNTND-------EKKFVQELRYV----CLTSNYNVTVFHPY---FIYFDQFLMVLPTTIQCITVAAFVMMFISLIFIP-NPVCSLWVAFSIISIEVGVVGFMTLWGVGLDSISMINLIMCIGFSVDFSAHISYHYMSCE 787
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000005221 (pep:novel supercontig:LSalAtl2s:LSalAtl2s276:209809:212602:-1 gene:EMLSAG00000005221 transcript:EMLSAT00000005221 description:"maker-LSalAtl2s276-augustus-gene-2.14") HSP 1 Score: 67.3958 bits (163), Expect = 1.247e-11 Identity = 48/191 (25.13%), Postives = 90/191 (47.12%), Query Frame = 0
Query: 433 DEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETH-QEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYW 622
DEI G + + +L++ +Y L D + ++ L + G +++ +++G+S G+ GF + IIPFL+L G D++F++++ + E +E I +V S+ +TS T+ F + + + +P +RAF L + + +F +T FI+ LD R E F W
Sbjct: 31 DEIVTSIDGGMYVFGVGFLLILIYSLLVTSDFHP-----VNQRVMLLLLGFMVIGMAIGSSFGL-GFHIGIIYADLHPIIPFLLLGIGVDDLFIIIKSTDNLSQKEKELPLKERIALVVQHSGVSITVTSLTDLVAFLISSTTSIPLLRAFCLSVALGISFLYFFVVTFFIAWYTLDERRIEEG--KAFLW 213
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000012098 (pep:novel supercontig:LSalAtl2s:LSalAtl2s867:155984:163315:1 gene:EMLSAG00000012098 transcript:EMLSAT00000012098 description:"maker-LSalAtl2s867-snap-gene-0.32") HSP 1 Score: 56.6102 bits (135), Expect = 3.008e-8 Identity = 37/140 (26.43%), Postives = 73/140 (52.14%), Query Frame = 0
Query: 825 FYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSA----GSTSFCRFFRPQHFVH 960
+ F++Q+L + TI S+ I+ I + ++TFI ++ +L + + +V I ++G M ++ I+L+ IS++ L+M +G SI++ +H +F+ N R + L G + S+ G T FF P + +
Sbjct: 667 LFPFFDQFLQVLPSTIYSVSITAIVVILITFILIP-NIVFTLWVTIALVSIEIGVLGFMVIFEINLDIISMICLIMCVGFSIDYSAHVSYHFVSMNIRNNSIRLKSXLXAYGPPIVQSAVSTMLGVTGL--FFLPSYIIR 803
BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Match: EMLSAP00000007475 (pep:novel supercontig:LSalAtl2s:LSalAtl2s429:50360:104533:1 gene:EMLSAG00000007475 transcript:EMLSAT00000007475 description:"maker-LSalAtl2s429-augustus-gene-1.9") HSP 1 Score: 55.4546 bits (132), Expect = 3.778e-8 Identity = 27/109 (24.77%), Postives = 67/109 (61.47%), Query Frame = 0
Query: 841 KSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSF 949
+++ I+ I IF++ +F L+ S ++L +++ +++G ++ W I+++ I+ VN+V++IG+ +++ H +FL G + +R+ ++ +IG + + G+T+F
Sbjct: 262 RNMGIACIVIFVILSLFLA-NLLVSFLVLCNVIITVVDIVGFLHFWGITIDTIACVNIVLSIGLCVDYSIHIAHFFLCASG-DAAERAASSVESIG--IAIINGGTTTF 366
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|449081276|sp|O35604.2|NPC1_MOUSE (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 417.542 bits (1072), Expect = 2.908e-126 Identity = 238/603 (39.47%), Postives = 347/603 (57.55%), Query Frame = 0
Query: 33 CNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
CN V+ PCSC DC C + + + + L+ M + ++ +F G ++ F+ E++ D N S + + G D+ L FT+WG FC P +IF S+ +G+ +++VTT+P+ELW++P S++R EK++FD+ FGPF+R Q+II+A N S YE G FGP +K E L +L LQ IE I N V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY + +L A WEK FI F+ + +NP ++ I+FT+ERSI DE+++E+ D+ T+ ISY++MF+YI+L+LG SC R L++SKI+L I G+LIV+ SV S+GIF ++ P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GRI+G+V P+M L+SF+E++ FF GA+S MPAV F+L+AGMA+LIDF +QITCF+SL+ LDI RQ +N DI +RG
Sbjct: 227 CNESVDEVTGPCSCQDCSIVCGPKPQP-PPPPMPWRIWGLDAMYVIMWVTYVAFLFVFFGALLAVWCHRRRYFVSEYTP----IDSNIAFSVNSSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNK-EILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYAD-YHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYN------DTERLQRAWAWEKEFISFVKNY-KNP----NLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVRG 803 HSP 2 Score: 195.282 bits (495), Expect = 1.154e-49 Identity = 107/235 (45.53%), Postives = 147/235 (62.55%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C T E K P F ++L FL DNP C K GHAAY ++ I + D + + A+ FMT+HTILK+S DY +A++ +R +AS I + ++ RVFPYS+FYVFYEQYLT+ DTI +L +S SIF+VT + G EL S++I+ +TI MI N+ G+M+LW ISLNA+SLVNLVM+ GIS+EFCSH + F +RV R+E L ++GSS+
Sbjct: 976 CVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYGSAVNI-----VGDDTY----IGATYFMTYHTILKTSADYTDAMKKARLIASNITETMR----SKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSV 1197
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|83305902|sp|O15118.2|NPC1_HUMAN (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 409.453 bits (1051), Expect = 2.806e-123 Identity = 246/635 (38.74%), Postives = 356/635 (56.06%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIP-EEMSYYNTEIEPCNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKI-ETQDNK-VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
PF I VFS P M N + C+ V+ +PCSC DC C + + L+ M I ++ L+F G F+ E++ D +S + + + A E L FTRWG+FC P VIF S++ +G+ ++RVTT+P++LW++P S++R EK++FD+ FGPF+R Q+II+A Y+ G FGP + L +L LQ IE I + DN+ V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY + KL A WEK FI F+ + +NP ++ I+FT+ERSI DE+++E+ D+ T+ ISY IMF+YI+L+LG SC+R L++SK++L I G+LIV+ SV S+G+F +I P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GR++G+V PSM L+SF+E+ FFLGA+S MPAV F+L+AG+A+ IDF +QITCF+SL+ LDI RQ +N DIF +RG
Sbjct: 200 QAPFTITPVFS-----DFPVHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPKPQP-PPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYT-PIDSNIAFSVNASDKGEASCCDPVSAAFEGCLRRL---FTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPL-DIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYAD-YHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYN------DTEKLQRAQAWEKEFINFVKNY-KNP----NLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRG 803 HSP 2 Score: 194.126 bits (492), Expect = 3.009e-49 Identity = 125/332 (37.65%), Postives = 179/332 (53.92%), Query Frame = 0
Query: 621 YWIRGPPTYIEL-------SNRXXXXXXYTLLNNEEETDEEIRFLKKREKY--LMYSGDRKFDLYHPWTTGLSSMD--DSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
Y GPP Y L S++ + N + ++I + + Y + ++ D Y W SS D++ + A C +C T E K P F R+L FL DNP C K GHAAYS ++ I L G V A+ FMT+HT+L++S D+ +AL+ +R +AS + + N RVFPYS+FYVFYEQYLT+ DTI +L +S +IF+VT + G EL S++I+ TI M+ N+ G+M+LW ISLNA+SLVNLVM+ GIS+EFCSH + F +RV+R+E L ++GSS+
Sbjct: 882 YLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRC---RPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNI-----LLGHG---TRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----GSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSV 1198
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|8134591|sp|P56941.1|NPC1_PIG (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 399.823 bits (1026), Expect = 7.013e-120 Identity = 240/636 (37.74%), Postives = 352/636 (55.35%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEE-MSYYNTEIEPCNIRVNG-KSPCSCTDCESSCASQIINDKNHH----LEYNN-YRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFS-IRADCT-DMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
PF I +FS +P M N + C+ V+ PCSC DC C + L + Y + SS+ +I G V F+ E++ I + +N + + F + G + L F +WG FC +P V+F S+ + +G+ ++RVTTDP++LW++P S++R+EK++FD FGPF+R+ Q+II+A N + Y G FGP + + L +L LQ IE I N V L+DIC PL+P + C I ++ +Y+Q+ LD + + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY + KL A WE FI F+ + +NP ++ I+F +ERSI DE+++E+ D+ TI ISY IMF+YI+++LG SC R L++SKI+L I G+LIV+ SV S+GIF +I P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GR++G+V PSM L+SF+E+ FFLG +S +PAV F+L+AGMA+LIDF +QITCF+SL+ LDI RQ +N D+ ++G
Sbjct: 200 QAPFTITPIFS-----DLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWSSYMAFLIVFFGAFFAVWCYRKRYFVSEYTPIDGNIAFSVNSSDKGQAFCCDPL------GAAFERGLRRLFAQWGAFCVRHPGCVVFFSLAFIVACSSGLVFIRVTTDPVDLWSAPGSQARREKEYFDTHFGPFFRMEQLIIRATNNQSHIYHPYPAGADVPFGPPLSR-DILHQVLDLQTAIENITASYNNETVTLQDICLAPLSPYNKNCTILSVLNYFQNSHSVLDHQVGDFFFVYAD-YHTHFLYCVRAPASLNDASLLHDPCLGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYN------DTEKLQRAQAWESEFINFVKNY-KNP----NLTISFMAERSIEDELNRESNSDLFTILISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYIGVPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGGLSVVPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVVCCVQG 803 HSP 2 Score: 194.897 bits (494), Expect = 1.488e-49 Identity = 107/235 (45.53%), Postives = 145/235 (61.70%), Query Frame = 0
Query: 707 CPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C T E K P F R+L FL DNP C K GHAAYS ++ I V A+ FMT+HT+L++S D+ +A++ +R +AS I R + E RVFPYS+FYVFYEQYLT+ DTI +L +S +IF+VT + G EL +++I+ VTI MI N+ G+M+LW ISLNA+SLVNLVM+ GIS+EFCSH + F +RV R+E L ++GSS+
Sbjct: 976 CIRCRPLTSEGKQRPQGEDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGNGS---------GVGATYFMTYHTVLQASADFIDAMQKARLIASNI----TRTMGLEASSYRVFPYSVFYVFYEQYLTVIDDTIFNLGVSLGAIFLVTVVLMGCELWATVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTLSTKGSRVDRAEEALAHMGSSV 1197
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|1100165154|sp|Q9VRC9.2|NPC1B_DROME (RecName: Full=Niemann-Pick type protein homolog 1B; Flags: Precursor) HSP 1 Score: 370.163 bits (949), Expect = 3.569e-109 Identity = 228/630 (36.19%), Postives = 331/630 (52.54%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFL--IGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPL-----TPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIR 624
+ PFQI++ +S D E Y + C C+C DCE SC L + L +F +A+I + F IF G F +T E+ F WGTFCA +PV V+ L GL GI ++ +TTDP+ELWA +S++R EKD+FD+ FGPFYR Q+ +KA N + F +E G FGP F +Y FL + LQ I K+ DN+ L K IC+ P+ TPT + C IQ+++ Y+Q D + + Y D N+ YL+ C R P M + C G PI+P +GG + +P Y A +V+TFL NYN S KL M+WEK F++F+ + + +DIA+ +ERSI D I + + G+++T+ ISY++MFVY+ ++LG SC+ FL ES+I LAIGG++IV+ SV S+G +G++D T++ E+IPFLVLA G DNIF++V QR +T E IG +G V PS+L T+ +E CF +G IS MPAV+ FA+YA +A+L+DF +QIT F++LMA+D R + D+ ++
Sbjct: 202 YVPFQINYKWSEDAEEGSNE--IYLDLSPLKCGESYEDSYACACIDCEESCPLTDAPTGPDEL-WKIAGLYGVTFILALIIACALSFFIFWGA----------------------------FGKTSAPSVCMPTLFGEFFYHGFRIWGTFCAKHPVIVLALCSWAIAGLSFGIRYMTITTDPVELWAGEESQTRIEKDYFDQHFGPFYRTNQMFVKAVNQTYFTHETSNG-VLNFGPAF-EYNFLKEVFELQDSIMKLGMADNEGLDK-ICYAPVLMAGETPTVDRCAIQSVYGYFQHDMDRFENS-YVDSNNYTINYLNQLEDCLRVP--------MMEDCFGTFGGPIEPGIAVGGMPKVAVGE--DPDYMLATGLVLTFLGRNYNDES-------KLEPNMKWEKLFVDFLRDY-----KSDRLDIAYMAERSIQDAIVELSEGEVSTVVISYVVMFVYVAIALGHIRSCRGFLRESRIMLAIGGIVIVLASVVCSLGFWGYLDVTTTMLAIEVIPFLVLAVGVDNIFIMVHTYQRLDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAIGCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVK 774 HSP 2 Score: 167.548 bits (423), Expect = 6.109e-41 Identity = 91/237 (38.40%), Postives = 142/237 (59.92%), Query Frame = 0
Query: 705 QKCPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
+ C + EN L P A F +Y+ +FL D P C KAG A+Y+ ++ +D G + V S FM + T +S+++Y LR R+++ EI N N A +F Y +FY++YEQYLT+WGD + SL +S ++IF+VT + TG ++ S+ I+L ++ I N++GMM+ W+I+LNAISLVNLV+ +GI +EF +H V+ F EG + +R+ +L GSS+
Sbjct: 953 EDCLPCERGFTENGLRPDAETFNKYIPYFLFDLPDAECAKAGRASYADAVIYT----IDDVGMST--VQDSYFMQYSTTSTTSEEFYSQLREVRRISGEINAMFKEN----NVDAEIFAYCVFYIYYEQYLTIWGDAMFSLGMSLVAIFLVTLLITGLDITSTFIVLFMVICILINMLGMMWAWSINLNAISLVNLVVCVGIGVEFVAHIVRSFKRAEGTAQ-ERARHSLNVTGSSV 1178
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|73921247|sp|Q6T3U3.1|NPCL1_RAT (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 365.155 bits (936), Expect = 6.082e-107 Identity = 207/615 (33.66%), Postives = 348/615 (56.59%), Query Frame = 0
Query: 18 SIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISS-FSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQK----EIEKIETQDNKVLLKDICHTPLTPTSNA---CNIQNLWSYWQDDPKELDKTG---YNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIF 620
++P+ + N +I PCN S CSC DC +SC + L + Y + ++ IIF F++ V++ R + S R + K ++ G FF WGT A++P+ V+ LS ++ + L G+ ++ +TTDP+ELW++P+S++R+EK F DE FGPF+R Q+ + A+N S+++Y+ L +K F I L L ++ ++ E + N + L+DIC+ PL P + + C + +L Y+Q++ L T N +T+ D + DHF+ C+ P++ TS+ SCM+ G P+ P+ +GG+ + Y +A A++ITF +NNY P + ++ A WE+ F++ + + +N + +AF++ERS+ DEI++ T D+ +SY+I+F+YI+L+LG + C R +ESK TL +GGV++V+ +V A++G + ++ P++L+I +++PFLVLA G DNIF+ V QR E + +IGR +G V PSMLL S +E+ CFFLGA++ MPAVR FAL +G+A+++DF +Q+T F++L++LD RQ + D+
Sbjct: 228 ALPDGIQPLNGKIAPCNESQGDDSAVCSCQDCAASCP---VIPPPEALRPSFYMGRMPGWLALIIIFTAVFVLLSAVLVRLRVV---SNRNKNKAEGPQEAPKLPHKHKLSPHTILGR--------FFQNWGTRVASWPLTVLALSFIVVIALAAGLTFIELTTDPVELWSAPKSQARKEKSFHDEHFGPFFRTNQIFVTARNRSSYKYDSLLLGSKNFSGILSLDFLLELLELQERLRHLQVWSPEAERN-ISLQDICYAPLNPYNTSLSDCCVNSLLQYFQNNRTLLMLTANQTLNGQTSLVD-WKDHFLYCANAPLTFKDGTSLALSCMADYGAPVFPFLAVGGYQGTD--------YSEAEALIITFSLNNY------PADDPRMAQAKLWEEAFLKEMESFQRN--TSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVL 810 HSP 2 Score: 174.096 bits (440), Expect = 6.606e-43 Identity = 94/244 (38.52%), Postives = 144/244 (59.02%), Query Frame = 0
Query: 707 CPNSDDATD------ENKLGPM-----AFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
CP++D + + LGP+ F +YL WFL D P + CPK G AAY S+ L DG VIAS FM +H L++S+D+ EALR SR LA+ I + R V + VFPY+I VFY+QYLT+ + I +L + F+ F+V ++ G ++ S ++ L++I+MI + +G+M +W IS NA+SL+NLV A+G+S+EF SH + F R++R++ V +GS++
Sbjct: 981 CPSTDTSFNCLKNCMNRTLGPVRPTAEQFHKYLPWFLNDPPNIRCPKGGLAAYRTSVN------LSSDG----QVIASQFMAYHKPLRNSQDFTEALRASRLLAANITADL-RKVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAKDATVFMGSAV 1213
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|425906049|sp|Q9UHC9.2|NPCL1_HUMAN (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 341.273 bits (874), Expect = 2.454e-98 Identity = 195/592 (32.94%), Postives = 328/592 (55.41%), Query Frame = 0
Query: 43 CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQK----EIEKIETQDNKVLLKDICHTPLTPTSNA---CNIQNLWSYWQDDPKELDKTGYN---DKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIR 624
CSC DC +SC + + L+ Y + + II L V +++ + ++ D S S + +++ L FF WGT+ A++P+ ++ LSV+ + L G+ + +TTDP+ELW++P S++R EK F D+ FGPF+R QVI+ A N S+++Y+ L K F I L L ++ ++ E Q N + L+DIC+ PL P + + C I +L Y+Q++ L T +T+ D + DHF+ C+ P++ T++ SCM+ G P+ P+ +GG+ Y +A A+++TF +NNY + DP +L A WE+ F+E + + + + F +ERS+ DEI++ T D+ SY+++F+YI+L+LG +S R +++SK TL +GGV +V+ +V A++G F ++ ++L+I +++PFLVL+ G DNIF+ V QR E + +IGR +G V PSMLL S +E+ CFFLGA++ MPAVR FAL +G+A+++DF +Q++ F++L++LD RQ + D+ ++
Sbjct: 254 CSCQDCAASCPAIA---RPQALDSTFYLGQMPGSLVLIIILCSVFAVVTILLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTL----------LGQFFQGWGTWVASWPLTILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRN-ISLQDICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVD-WKDHFLYCANAPLTFKDGTALALSCMADYGAPVFPFLAIGGY--------KGKDYSEAEALIMTFSLNNYP--AGDP----RLAQAKLWEEAFLEEMRAFQR--RMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVK 814 HSP 2 Score: 137.502 bits (345), Expect = 1.528e-31 Identity = 89/233 (38.20%), Postives = 130/233 (55.79%), Query Frame = 0
Query: 724 FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRA-YLDQDGF----TEYDVI------------ASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
F +YL WFL D P + CPK G AAYS S+ + LD EY S FM +H LK+S+DY EALR +R+LA+ I + R V + VFPY+I VFYEQYLT+ + + L + + F V+ + G +L S L+ L++IVMI + +G M LW IS NA+SL+NLV A+G+S+EF SH + F ++R++ +++GS++
Sbjct: 1008 FHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLLDSTSRFMAYHKPLKNSQDYTEALRAARELAANITADL-RKVPGTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAV 1239
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|73921246|sp|Q6T3U4.1|NPCL1_MOUSE (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 328.946 bits (842), Expect = 4.377e-94 Identity = 206/613 (33.61%), Postives = 340/613 (55.46%), Query Frame = 0
Query: 18 SIPEEMSYYNTEIEPCN-IRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQK----EIEKIETQDNKVLLKDICHTPLTPTSNA---CNIQNLWSYWQDDPKELDKTG---YNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDI 619
++ + M + +I PCN + + CSC DC +SC + L + Y + + II IF V + + + A + N T S+ N + L FF WGT A++P+ V+ LS ++ + L G+ ++ +TTDP+ELW++P+S++R+EK F DE FGPF+R Q+ + AKN S+++Y+ L K F I L ++ ++ E Q N + L+DIC+ PL P + + C + +L Y+Q++ L T N +T+ D + DHF+ C+ P++ T++ SC++ G P+ P+ +GG+ + Y +A A++ITF INNY P + ++ A WE+ F++ + + ++ IAF++ERS+ DEI++ T D+ ISYLI+F+YI+L+LG + R ++SK TL +GGV +V+ +V A++G + ++ P++L+I +++PFLVLA G DNIF+ V QR E + +IGR +G V PSMLL S +E+ CFFLGA++ MPAVR FAL +G+A++ DF +Q+T F++L++LD RQ + D+
Sbjct: 228 ALADGMKPLDGKITPCNESQGEDSAACSCQDCAASCP---VIPPPPALRPSFYMGRMPGWLALII------IFTAVFVLLSVVLVYLRVASNRNKNKTAGSQ----EAPNLPRKRRFSPHTVLGRFFESWGTRVASWPLTVLALSFIVVIALSVGLTFIELTTDPVELWSAPKSQARKEKAFHDEHFGPFFRTNQIFVTAKNRSSYKYDSLLLGPKNFSGILSLDLLQELLELQERLRHLQVWSHEAQRN-ISLQDICYAPLNPHNTSLTDCCVNSLLQYFQNNHTLLLLTANQTLNGQTSLVD-WKDHFLYCANAPLTYKDGTALALSCIADYGAPVFPFLAVGGYQGTD--------YSEAEALIITFSINNY------PADDPRMAHAKLWEEAFLKEMQSFQRS--TADKFQIAFSAERSLEDEINRTTIQDLPVFAISYLIVFLYISLALGSYSRWSRVAVDSKATLGLGGVAVVLGAVVAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTSMPAVRTFALTSGLAIIFDFLLQMTAFVALLSLDSKRQEASRPDV 809 HSP 2 Score: 172.17 bits (435), Expect = 2.520e-42 Identity = 92/244 (37.70%), Postives = 144/244 (59.02%), Query Frame = 0
Query: 707 CPNSDDATD------ENKLGPM-----AFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
CP++D + + LGP+ F +YL WFL D P + CPK G AAY S+ L DG +IAS FM +H L++S+D+ EALR SR LA+ I + R V + VFPY+I VFY+QYLT+ + I +L + F+ F+V ++ G ++ S ++ L++I+MI + +G+M +W IS NA+SL+NLV A+G+S+EF SH + F R++R++ + +GS++
Sbjct: 981 CPSTDTSFNCLKNCMNRTLGPVRPTTEQFHKYLPWFLNDTPNIRCPKGGLAAYRTSVN------LSSDG----QIIASQFMAYHKPLRNSQDFTEALRASRLLAANITAEL-RKVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDIRSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAKDATIFMGSAV 1213
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|37999494|sp|Q19127.2|NPC1_CAEEL (RecName: Full=Niemann-Pick C1 protein homolog 1; Flags: Precursor) HSP 1 Score: 196.052 bits (497), Expect = 7.228e-50 Identity = 162/648 (25.00%), Postives = 287/648 (44.29%), Query Frame = 0
Query: 1 MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVN-GKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIF-LIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHK--YEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKT--------------NHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQA-NAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKR----FLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQ--RAQRYGPESTETHQ--EYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFY 621
++ P F+ + +Y N C+ G CS ++C + +I+ + + + N+ + IF ++ F+ + V++ F+ S D T++ T S + R N IK G + ++ G P F+ + + G+ + + +T+ +++W+SP+SR+RQE+ F+ FG R Q+++ + D K +GP+FHK +E L +L K I ++ + L D+C+ P+ P + C I + +Y+Q + + LD ++T D +++H C P+SQ ++ + SCM G P P V G N HQA N++++T L+ R E++K L WEK F++F ++ E + + +F +ERSI DEI + +I T+ I+ + Y+T SLG C+ L+ S+I L + V+I ++S S GIF + F+V G FM+V+ QR Q E +G ++ +P+M +S + FF+G + +PA+R F LYAG+A+LID + T F++L D R+ + F+
Sbjct: 203 LNIPIHTKFLLYDPIKTPPSDRSTYMNVNFTGCDKSARVGWPACSTSECNKEEYANLIDLDDG--KTSGQTCNVHGIACLNIFVMLAFIGSLAVLLCVGFVFT-SYDEDYTNLRQTQSGEESPKR--NRIKRTGAWIHNFMENNARDIGMMAGRNPKSHFFIGCAVLIFCLPGMIYHKESTNVVDMWSSPRSRARQEEMVFNANFGRPQRYQQIML-------LSHRDFQSSGKLYGPVFHKDIFEELFDILNAIKNISTQDSDGRTITLDDVCYRPMGPGYD-CLIMSPTNYFQGNKEHLDMKSNKEETVSEDDDAFDYFSSEATTDEWMNHMAACIDQPMSQKTKSGL--SCMGTYGGPSAPNMVFG----------KNSTNHQAANSIMMTILVTQ-----RTEPEIQKAEL---WEKEFLKFCKEY---REKSPKVIFSFMAERSITDEIENDAKDEIVTVVIALAFLIGYVTFSLGRYFVCENQLWSILVHSRICLGMLSVIINLLSSFCSWGIFSMFGIHPVKNALVVQFFVVTLLGVCRTFMVVKYYAQQRVSMPYMSPDQCPEIVGMVMAGTMPAMFSSSLGCAFSFFIGGFTDLPAIRTFCLYAGLAVLIDVVLHCTIFLALFVWDTQRELNGKPEFFF 814 HSP 2 Score: 98.9821 bits (245), Expect = 1.129e-19 Identity = 70/232 (30.17%), Postives = 113/232 (48.71%), Query Frame = 0
Query: 724 FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILK--SSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIG----SSLPTSSAGSTSF 949
F R+L FLED P C G A++ ++ R + AS FMTFH L +S D+ +A+ +R ++ +E +I+ A VF YS + FYEQY T+ L I+ + +F + + G ++ + ++ V +++ MY++NI +NA+S NLVM+ GI IEF + +K + R+E T+ +IG S + AGST F
Sbjct: 1030 FYRHLRHFLEDTPNSECVFGGRASFKDAISFTSRGRIQ----------ASQFMTFHKKLSISNSSDFIKAMDTARMVSRRLERSID-------DTAHVFAYSKIFPFYEQYSTIMPILTTQLFITVVGVFGIICVTLGIDVKGAACAVICQVSNYFHIVAFMYIFNIPVNALSATNLVMSSGILIEFSVNVLKGYACSLRQRAKDRAESTVGSIGPIILSGPVVTMAGSTMF 1244
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|74676548|sp|Q12200.1|NPC1_YEAST (RecName: Full=Niemann-Pick type C-related protein 1; Flags: Precursor) HSP 1 Score: 168.703 bits (426), Expect = 2.330e-41 Identity = 159/628 (25.32%), Postives = 285/628 (45.38%), Query Frame = 0
Query: 3 TPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFI--------KEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIF-WLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEI-EKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTE-THQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDI 619
+PFQI++ + A+ +E +N E+ C+ + + C+C+DC+ SC HL+ + + F + LIF + F+ K ++ D + ++GS + S N + L FT+ G F P ++ +V IF + + TDPI LW S S +EK++FD+ FGPFYR Q+ + E GP+ YE L ++ I E++++ +N + +D+C P ++ C I++ Y+Q + D++ C + PV+ C+ P+K + F++ A+A V+T L+ N+ Q A WE+ E++ ++ PE + I+F +E S+ E++ DI+T+ ISYL+MF+Y T +L +R ++++ L I G+LIV+ S+ + G +TLII E+IPFL+LA G DNIF++ R + E + + I +G + PS+L++ ++ CF + A MPAV FA+Y+ ++++ + +Q+T ++S+++L +R N+ I
Sbjct: 196 SPFQINYKYD---LANEEKEWQEFNDEVYACD---DAQYKCACSDCQESCP---------HLK--PLKDGVCKVGPLPCFSLSVLIFYTICALFAFMWYYLCKRKKNGAMIVDDDIVPESGSLDESETNVFESFNNETNFFNGKLANLFTKVGQFSVENPYKILITTVFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFV----------------VNETGPVL-SYETLHWWFDVENFITEELQSSEN-IGYQDLCFRPTEDST--CVIESFTQYFQG------------ALPNKDSWKRELQECGKFPVN----------CLPTFQQPLKTNLL-----------FSDDDILNAHAFVVTLLLTNHTQS------------ANRWEERLEEYLLD-LKVPEGLR---ISFNTEISLEKELNN--NNDISTVAISYLMMFLYATWAL------RRKDGKTRLLLGISGLLIVLASIVCAAGFLTLFGLKSTLIIAEVIPFLILAIGIDNIFLITHEYDRNCEQKPEYSIDQKIISAIGRMSPSILMSLLCQTGCFLIAAFVTMPAVHNFAIYSTVSVIFNGVLQLTAYVSILSL--YEKRSNYKQI 727 HSP 2 Score: 95.1301 bits (235), Expect = 1.329e-18 Identity = 63/193 (32.64%), Postives = 100/193 (51.81%), Query Frame = 0
Query: 724 FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYF 916
F YLS ++ + P CP G A YS +L + E V AS F T H L+S KD+ +A +++S + +F YS FY+F+ QY T+ T+K + + I IF ++ +F + SS ++ + + MI ++ +M L ISLNA+SLVNL++ +G+ +EFC H V+ F
Sbjct: 910 FMEYLSIWI-NAPSDPCPLGGRAPYSTALV-----------YNETSVSASVFRTAHHPLRSQKDFIQAYSDGVRISSSFP------------ELDMFAYSPFYIFFVQYQTLGPLTLKLIGSAIILIFFISSVFLQ-NIRSSFLLALVVTMIIVDIGALMALLGISLNAVSLVNLIICVGLGVEFCVHIVRSF 1077
BLAST of EMLSAG00000008403 vs. SwissProt
Match: gi|37999933|sp|P34389.2|NPC2_CAEEL (RecName: Full=Niemann-Pick C1 protein homolog 2; Flags: Precursor) HSP 1 Score: 147.902 bits (372), Expect = 7.609e-35 Identity = 148/641 (23.09%), Postives = 264/641 (41.19%), Query Frame = 0
Query: 4 PFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIIN-DKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIET--QDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYN--DKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDN----TSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYG-----PE-STETHQEYIGRIVGDVVPSMLLTSFTESTCFFL-GAI-----SGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYW 622
P +F FS K A N PC+ K P C DC ++ A Q+++ K HL + + F +L+ + + + FI ++S + G + +L+ R+ +P+ + L +++A C+G F T ++ ++ +R+ + F +FGP +RI Q+ I + + P+F + + +L I+ + ++ V L DIC+ P+ ++ C I + +Y+Q+ + G D +D + +H C RNP++ + + M SC + PI P V GG N S Y+ A ++IT LI R P++ A+ WE F+ + ++ KH + F +E S+ +EI D I+ + +++ LG N +S L+ K+ ++I V+I +ISV S+G+F AT ++ F++ G + IF++++ Q G P S I ++ +P +L S STC FL G + MPAV FA +AG+A+L+D + + L D R+ +I+ W
Sbjct: 203 PINTEFQFSRMKNA--------MNIPTTPCHKSAGPKVPACGAIDCPTN-AHQLVDISKVEHLGTKVFHPHFPDFE----WLLKICGCLALTVLLVFILKYSCHRRSAPNGEDGCY----------VDLGKGNLEVQFEGLCARYANAVIKHPLIFVSLGLIVAAACCSGNFKFHSLTHSVDQVSAADGETRRNEKKFIHSFGPNHRIEQIFINLPPTTKSMFNM---------PLFEE------MFQLVGNIQNLTACYGNSSVKLDDICYKPIG-KNHGCAIMSPTNYFQNKWTNFENAGPPTIDDEIFDDQHWEHLKYCIRNPLTVSTYSEM--SCFGEFSGPIDPILVFGG---SNESIKGAEMYYTARTIMITVLI-------RGPEDQ-----AIAWETAFLNMMSRY-----EMKHANFTFMTETSVAEEIHTAVETDKIVSVIACAAVLIWVITMLGINHWPESSILSALVHHKLLISISAVMISVISVWCSIGMFSLFGVHATDNAIVVLFFVITCLGINRIFVIIRTFQANGHCYGLPNISYREMNHRISNVMRRSIPIVLTNSLICSTCLFLAGGVLPYVSVSMPAVEVFARHAGLAILMDTAFYLLVMLPLFQYDARREMSGKCEIWPW 782 HSP 2 Score: 82.8037 bits (203), Expect = 1.056e-14 Identity = 58/215 (26.98%), Postives = 103/215 (47.91%), Query Frame = 0
Query: 724 FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSS 938
F R L FLE P + C G A ++ + + + F+ + F + L S Y+A R ++ LA +IE + E +V+ YS F+ +YEQYLT+ + + F+ +F L SL+ + ++ +LM MYL I++N +S++N+ M++GI++EF + F + + R +R+ LV+ GS+
Sbjct: 981 FYRNLHHFLETPPSIQCAHGGMALAKPAINLTRNGKIQSAYFSTF------FKKLN--LSDSIQLYDAWRFAKYLADDIEREL------EIPGVKVYVYSTFFPYYEQYLTLSTTVYTLVVLVLFVAFVTISLFLRVNLAGSLVTVFVLLSSYLHLMEWMYLLGITVNVVSVINMAMSLGIAVEFFGQMLHGFYNSKKPKREERAFAALVSNGST 1181
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: gb|KYB26045.1| (Niemann-Pick C1 protein-like Protein [Tribolium castaneum]) HSP 1 Score: 501.901 bits (1291), Expect = 8.908e-158 Identity = 284/642 (44.24%), Postives = 378/642 (58.88%), Query Frame = 0
Query: 4 PFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTF---FSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNA------CNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPTYIELSNR 635
PFQI+++ S + N EI PCN + KS CSC DCE SC + + F M I+F +G L+F+ VV E + ++ DT S + + + ++ G + D +L FF WGT CA P V+FL + +GL GI +L+VTTDP+ELWASP SRSR EK++FD F PFYR QVIIKA NL + GE FGP F FL +L+LQ+ I+ I D L IC PL C +Q++W Y+Q+D + D+T D YLD+FI C++NP + C++ G P+ P +GGFL + P Y A AV++TFL+NNY+ + KL AMEWEK F+ F+ + + E +M+IAFTSERSI DE+ +E+ D+ TI +SY+IMF YI +SLG +C R LI+SKITL +GGVLIV+ SV +SVG+FGF+ PATLII E+IPFLVLA G DNIF+LVQ QR G + TETH ++IGR +G V PSMLLTS +ES CFFLG++S MPAV+AFALYAGMALL DF +QITCF+SL++LD RQ N +DI +I+G I +N+
Sbjct: 222 PFQINYLNSTGPVDKDGVKYQPLNPEITPCNKAFDSKSAACSCVDCEESCPVPPPQ-PPAPQPFTIAGFDGYFFLMIIVFCVGTLMFLLVVFVCPSRAEIGVTSEMGHELDTHSINKMPGEYESSSSFLEKLGANTDTFLQRFFEWWGTICAERPWLVLFLGACVVVGLGHGIKYLKVTTDPVELWASPTSRSRIEKEYFDSHFEPFYRNEQVIIKAVNLPQIHHNTSNGEVV-FGPAFDA-TFLKEVLKLQERIKAIGA-DTDYALGRICFAPLRSVGKVSTDVEECVVQSIWGYYQNDEETFDETDV-DPDGFETNYLDYFISCAQNPYNP--------KCLAPYGGPVDPAIAMGGFLQPGENLSKQPNYQNATAVILTFLVNNYHNKT-------KLSPAMEWEKAFVAFMKNYTTS-EKPSYMEIAFTSERSIEDELDRESQSDVVTILVSYIIMFAYIAVSLGQVNTCSRLLIDSKITLGLGGVLIVLASVVSSVGLFGFVGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQREGKKPTETHAQHIGRTLGQVGPSMLLTSVSESCCFFLGSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDICCFIKGSKKEIVQTNQ 842 HSP 2 Score: 224.557 bits (571), Expect = 2.941e-59 Identity = 110/221 (49.77%), Postives = 153/221 (69.23%), Query Frame = 0
Query: 721 PMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSL--YIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
P F Y+S+FL+DNP C KAGHAAYS+ + K +L + G AS FM +HTILK+SKDYYE++R +R++++ I N IN + + + VFPYS+FYVFYEQYLTMW DT++S+ IS +IF+VTF+ G + SS ++++TI MI NL G+MY W+I+LNA+SLVNLVMA+GI++EFCSH V F RV+R+ +L +GSS+
Sbjct: 1019 PNDFEHYVSFFLQDNPDETCAKAGHAAYSQGVNYATNKTTHLSKVG-------ASYFMAYHTILKTSKDYYESMRSARKVSANITNTINTKI--PSSQIEVFPYSVFYVFYEQYLTMWPDTLQSMAISLAAIFVVTFLLMGLDFFSSAVVVITITMIVVNLGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSLKTTRVERAADSLTRMGSSI 1230
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: gb|EFA11848.2| (Niemann-Pick C1 protein-like Protein [Tribolium castaneum]) HSP 1 Score: 485.337 bits (1248), Expect = 3.940e-151 Identity = 287/688 (41.72%), Postives = 382/688 (55.52%), Query Frame = 0
Query: 4 PFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT---------------------------------SRFI-------------KEFSIRADCTDMNDTGSSKTF---FSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNA------CNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPTYIELSNR 635
PFQI+++ S + N EI PCN + KS CSC DCE SC + + F M I+F +G L+F+ VV SR + K S+ ++ DT S + + + ++ G + D +L FF WGT CA P V+FL + +GL GI +L+VTTDP+ELWASP SRSR EK++FD F PFYR QVIIKA NL + GE FGP F FL +L+LQ+ I+ I D L IC PL C +Q++W Y+Q+D + D+T D YLD+FI C++NP + C++ G P+ P +GGFL + P Y A AV++TFL+NNY+ + KL AMEWEK F+ F+ + + E +M+IAFTSERSI DE+ +E+ D+ TI +SY+IMF YI +SLG +C R LI+SKITL +GGVLIV+ SV +SVG+FGF+ PATLII E+IPFLVLA G DNIF+LVQ QR G + TETH ++IGR +G V PSMLLTS +ES CFFLG++S MPAV+AFALYAGMALL DF +QITCF+SL++LD RQ N +DI +I+G I +N+
Sbjct: 222 PFQINYLNSTGPVDKDGVKYQPLNPEITPCNKAFDSKSAACSCVDCEESCPVPPPQ-PPAPQPFTIAGFDGYFFLMIIVFCVGTLMFLLVVFVCPSRAEIVGLVTGHGSEEMRAAVGRRLAGVDRQSRLVLGSDEEDSPLQDSKRSSVTSEMGHELDTHSINKMPGEYESSSSFLEKLGANTDTFLQRFFEWWGTICAERPWLVLFLGACVVVGLGHGIKYLKVTTDPVELWASPTSRSRIEKEYFDSHFEPFYRNEQVIIKAVNLPQIHHNTSNGEVV-FGPAFDA-TFLKEVLKLQERIKAIGA-DTDYALGRICFAPLRSVGKVSTDVEECVVQSIWGYYQNDEETFDETDV-DPDGFETNYLDYFISCAQNPYNP--------KCLAPYGGPVDPAIAMGGFLQPGENLSKQPNYQNATAVILTFLVNNYHNKT-------KLSPAMEWEKAFVAFMKNYTTS-EKPSYMEIAFTSERSIEDELDRESQSDVVTILVSYIIMFAYIAVSLGQVNTCSRLLIDSKITLGLGGVLIVLASVVSSVGLFGFVGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQREGKKPTETHAQHIGRTLGQVGPSMLLTSVSESCCFFLGSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDICCFIKGSKKEIVQTNQ 888 HSP 2 Score: 224.557 bits (571), Expect = 2.718e-59 Identity = 110/221 (49.77%), Postives = 153/221 (69.23%), Query Frame = 0
Query: 721 PMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSL--YIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
P F Y+S+FL+DNP C KAGHAAYS+ + K +L + G AS FM +HTILK+SKDYYE++R +R++++ I N IN + + + VFPYS+FYVFYEQYLTMW DT++S+ IS +IF+VTF+ G + SS ++++TI MI NL G+MY W+I+LNA+SLVNLVMA+GI++EFCSH V F RV+R+ +L +GSS+
Sbjct: 1065 PNDFEHYVSFFLQDNPDETCAKAGHAAYSQGVNYATNKTTHLSKVG-------ASYFMAYHTILKTSKDYYESMRSARKVSANITNTINTKI--PSSQIEVFPYSVFYVFYEQYLTMWPDTLQSMAISLAAIFVVTFLLMGLDFFSSAVVVITITMIVVNLGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSLKTTRVERAADSLTRMGSSI 1276
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: EFX69947.1 (hypothetical protein DAPPUDRAFT_328579 [Daphnia pulex]) HSP 1 Score: 485.723 bits (1249), Expect = 5.164e-151 Identity = 276/636 (43.40%), Postives = 384/636 (60.38%), Query Frame = 0
Query: 3 TPFQIDFVFSGDKXASIPEEMSYYNTEIEPC-NIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLI---GFLIFV----GVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVS--------QAAETSMKQ-SCMSKGGIPIKPYFVLGGFLSGNASDFTNPK-YHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIF 620
+PF I F + D ++ + + PC + N CSC DC SC +S F M ++FL FL+ V V +R +K S++ + + T S + + ++ AG +++ L FFT WGTFCA +P V+ + +A L G+ +L VT DP+ELWASP+SRSRQEKD+FD++F PFYR QVI+ A+ + F YE L G TK FGP F + +FLL +L LQ +IE + DN L DIC+ P+ P N C IQ++ +WQ L K+ +N TYLDH I CS+NP+ Q +++Q CM++ G P PY VLGGF +G T+ Y A A+++TF++ N ++D +L A +WEK F+E++ W +N + K+M +A+ +ERSI DE+++ + D+ TI ISY IMF YI ++LG S R L++SKITL IGGV+IV++SV AS+G +G++ PATLII E+IPFLVLA G DNIF+LVQ QR + ETH+E+IGRIVG+V PSMLL+S +E+ CFFLGA+SGMPAV+AFALYAGMALL+ F +Q+TCFI L +LD ARQ N DIF
Sbjct: 283 SPFDIYFQYIPDG-ETVTHVVEPFAPPAIPCYEVISNSSGTCSCVDCTGSCPVPKPWPPLPEPWTIGSMYGVS-FVMLMVFLAVSGTFLVTVFWKWHVDQVARGVKRRSLQPTISTTSSTDSQYEYVEGSF--MERAGASMEKALESFFTAWGTFCARWPWMVLIFGLSVAAALTVGVVFLEVTIDPVELWASPESRSRQEKDYFDKSFTPFYRTEQVILHAEGIEGFDYETLSG-TKRFGPAF-QLDFLLEVLHLQHDIEAL-MGDNGTHLNDICYMPMKPDVNECTIQSVLGWWQGREDYLLKSVVGTTNGYNYTYLDHAIYCSKNPLMPYDNNFKWQNENGTLEQIGCMAEYGGPAFPYVVLGGFRNGENESVTDESLYMNATALILTFIVQNIA--NKD-----QLGPAKDWEKKFLEYMKFWKKN-KMPKYMSVAYMAERSIEDELTRASQSDVITIAISYCIMFAYIAIALGQARSFSRLLVDSKITLGIGGVIIVLLSVVASIGFYGYVGVPATLIIIEVIPFLVLAVGVDNIFILVQTYQREPRRANETHEEHIGRIVGEVAPSMLLSSISEAFCFFLGALSGMPAVKAFALYAGMALLLAFLLQMTCFIGLFSLDTARQESNRLDIF 903 HSP 2 Score: 218.394 bits (555), Expect = 2.936e-57 Identity = 117/239 (48.95%), Postives = 161/239 (67.36%), Query Frame = 0
Query: 704 CQKCPNSDDATDENKL--GPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASN-FMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C +C + DE L P +L +FL+DNP NCPK GHAAY +++ D TE V+ +N FMT+HTIL++SKD+Y +L +R +A I ++ N+TN N VFPYSIFYV+YEQYLTMW D + SL IS +IF+VTFI G ++ SS+++L+TI+MI +L G+MYLW+I+LNA+SLVNLVMA+GIS+EFCSH V+ F R+ RS+ +LV +GSS+
Sbjct: 1082 CNECNKT--FIDEENLWPDPKTLNFWLPYFLKDNPCENCPKGGHAAYGQAM--------QYDNVTE--VVGANYFMTYHTILRTSKDFYSSLIEARVIADSISETLS-NITNSN--VEVFPYSIFYVYYEQYLTMWRDVLVSLSISIGAIFVVTFILLGLDIHSSVVVLITIIMILVDLFGLMYLWDITLNAVSLVNLVMAVGISVEFCSHIVRAFAMSIEPTRIARSKESLVRMGSSV 1305
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: EFX76733.1 (hypothetical protein DAPPUDRAFT_321920 [Daphnia pulex]) HSP 1 Score: 483.411 bits (1243), Expect = 1.843e-150 Identity = 274/636 (43.08%), Postives = 381/636 (59.91%), Query Frame = 0
Query: 3 TPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRV-NGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLI---GFLIFV----GVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPV---------SQAAETSMKQ-SCMSKGGIPIKPYFVLGGFLSGNASDFTNPK-YHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDI 619
+PF I F + D ++ + + + PC + N CSC DC SC +S F M ++FL FL+ V V +R +K S++ + + T S + + ++ AG +++ L FFT WGTFCA +P V+ + +A L G+ +L VT DP+ELWASP+SRSRQEKD+FD++F PFYR QVI+ A+ + F YE L G TK FGP F + +FLL L LQ +IE + DN L DIC+ P+ P N C IQ++ +WQ L K+ +N TYLDH I CS+NP+ +++Q CM++ G P PY VLGGF +G T+ Y A A+++TF++ N + +L A +WEK F+E++ W +N + K+M +A+ +ERSI DE+++ + D+ TI ISY IMF YI ++LG S R L++SKITL IGGV+IV++SV AS+G +G++ PATLII E+IPFLVLA G DNIF+LVQ QR + ETH+E+IGRIVG+V PSMLL+S +E+ CFFLGA+SGMPAV+AFALYAGMALL+DF +Q+TCFI L +LD ARQ N DI
Sbjct: 240 SPFDIYFQYIPDGE-TVTDVVEPFAPPAIPCYEAISNTSGACSCVDCTGSCPVPKPWPPLPEPWTIGSMYGVS-FVMLMVFLAVSGTFLVTVFWKWHVDRVARGVKRRSLQPTISTTSSTDSQYEYVEGSF--MERAGASMEKALESFFTAWGTFCARWPWMVLIFGLSVAAALTVGVVFLEVTIDPVELWASPESRSRQEKDYFDKSFTPFYRTEQVILHAEGIEGFDYETLSG-TKRFGPAF-QLDFLLEALHLQHDIEAL-MGDNGTHLNDICYMPMKPDVNECTIQSVLGWWQGREDYLLKSVVGTTNGYNYTYLDHAIYCSKNPLMPYDNNFKWQNETTGALEQIGCMAEYGGPAFPYVVLGGFRNGENESVTDESLYMNATALILTFIVQNI-------ADKDQLGPAKDWEKKFLEYMKFWKEN-KMPKYMSVAYMAERSIEDELTRASQSDVITIAISYCIMFAYIAIALGQARSFSRLLVDSKITLGIGGVIIVLLSVVASIGFYGYVGVPATLIIIEVIPFLVLAVGVDNIFILVQTYQREPRRANETHEEHIGRIVGEVAPSMLLSSISEAFCFFLGALSGMPAVKAFALYAGMALLLDFLLQMTCFIGLFSLDTARQESNRLDI 860 HSP 2 Score: 219.164 bits (557), Expect = 1.614e-57 Identity = 118/239 (49.37%), Postives = 162/239 (67.78%), Query Frame = 0
Query: 704 CQKCPNSDDATDENKL--GPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASN-FMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C +C + DE L P F +L +FL+DNP NCPK GHAAY +++ D TE V+ +N FMT+HTIL++SKD+Y +L +R +A I ++ N+TN K VFPYSIFYV+YEQYLTMW D + SL IS +IF+VTFI G ++ SS+++L+TI+MI +L G+MYLW+I+LNA+SLVNLVMA+GIS+EFCSH V+ F R+ RS+ +LV +GSS+
Sbjct: 1040 CNECNKT--FIDEENLWPDPNTFNFWLPYFLKDNPCENCPKGGHAAYGQAM--------QYDNVTE--VVGANYFMTYHTILRTSKDFYSSLIEARVIADSISETLS-NITN--SKVEVFPYSIFYVYYEQYLTMWRDVLVSLSISIGAIFVVTFILLGLDIHSSVVVLITIIMILVDLFGLMYLWDITLNAVSLVNLVMAVGISVEFCSHIVRAFAVSIEPTRIARSKESLVRMGSSV 1263
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: XP_006570442.1 (PREDICTED: Niemann-Pick C1 protein isoform X1 [Apis mellifera]) HSP 1 Score: 473.396 bits (1217), Expect = 1.502e-146 Identity = 287/675 (42.52%), Postives = 390/675 (57.78%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXAS-IPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLE----YNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRAD-------------------------CTDMNDT----GSSKTFFSRTINS----------IKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTP------TSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+ PFQI ++ + + S IP + ++ PCN +N +P CSC DCE+SC Y++Y + M I F+ G +F+ ++ K+ R + D D+ S + + S I+ G D+ L FF RWGT CA+ P V+FL L +GL GI ++ VTTDP+ELWA+PQSRSR EK++FD+ F PFYR Q+II + L + G+ FGP+F+ FL + +LQ+EI++I T +N L +IC PLT T++ C IQ++W YWQD + D + +D N YLDHFI+CS+N + C++ G PI+P +GGFLS D NP Y +A AV++T L+NNY+ S KLH AMEWEK++IEF+ W + + MDIAFTSERSI DE+++E+ D+ TI +SY+IMF YI +SLG +C R LI+SKITL +GGVL+V+ SV SVG+FGFI PATLII E+IPFLVLA G DNIF+LVQ QR E+ E+IGRI+G V PSMLLTS +ES CFFLG +S MPAV+AFALYAGMALL+DF +Q+TCF+SL+ALD RQ N D+ ++ G
Sbjct: 222 YVPFQITYINTDEPIDSFIP-----VDPKVTPCNKALNKNTPACSCVDCEASCPVPPPVPPLPRPSTIFGYDSYAV-----IMLITFICGSTLFILSIVCFSNRKQIVARGEEVGRQVGRRLAAGLHHPGDGARIALAADQEDSPLQSKRSSVISADDLPSGFDDEEQSTFIERLGAGTDKLLAEFFCRWGTACASRPWFVLFLGFLFIIGLGHGIKYIHVTTDPVELWAAPQSRSRVEKEYFDQHFEPFYRTEQIIITSVGLPNIIHNTSNGQIT-FGPVFND-TFLKTVYKLQEEIKQITTPNNYTL-ANICFAPLTSPFTGPLTASQCVIQSIWGYWQDSIETFDFSTTDDD-NFTVNYLDHFIVCSQN--------AYNPECLAPYGGPIEPAVAVGGFLS-PGQDLHNPSYEKATAVILTILVNNYHNKS-------KLHPAMEWEKSYIEFMKNWTTT-KKPEFMDIAFTSERSIEDELNRESQSDVLTILVSYIIMFAYIAISLGQIKNCSRLLIDSKITLGLGGVLLVLASVVCSVGLFGFIGIPATLIIIEVIPFLVLAVGVDNIFILVQTHQRESRRPNESIPEHIGRILGQVGPSMLLTSVSESCCFFLGGLSDMPAVKAFALYAGMALLVDFVLQVTCFVSLLALDTIRQANNKLDVCCFVHG 865 HSP 2 Score: 220.32 bits (560), Expect = 6.011e-58 Identity = 116/244 (47.54%), Postives = 155/244 (63.52%), Query Frame = 0
Query: 701 LNICQKCPNSDDATDENKLG---PMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVT--NENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
L C C N++G P F RY+S+FL+DNP C KAGHAAY + Y+ V AS FM +HTILK+S DYYE++R +R +++ I N IN + ++N VFPYSIFYVFYEQYLTMW DT+ S+ IS I+IF VTF G ++ SS+++++TI MI N+ G+MY W+I+LNA+SLVNLVMA+GI++EFCSH V F RV+R L N+GSS+
Sbjct: 1034 LKYCSSC-----NITRNEIGRPIPTDFDRYVSFFLQDNPDDTCAKAGHAAYGHGV-----NYVTDPTTGLSKVGASYFMAYHTILKTSADYYESMRAARTVSANITNMINDYLKSIDDNSTVEVFPYSIFYVFYEQYLTMWPDTLYSIGISLIAIFAVTFFLMGLDIFSSVVVVITITMIVVNIGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSVKTTRVERVADALTNMGSSI 1267
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: XP_006570443.1 (PREDICTED: Niemann-Pick C1 protein isoform X2 [Apis mellifera]) HSP 1 Score: 471.855 bits (1213), Expect = 2.856e-146 Identity = 287/675 (42.52%), Postives = 390/675 (57.78%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXAS-IPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLE----YNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRAD-------------------------CTDMNDT----GSSKTFFSRTINS----------IKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTP------TSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+ PFQI ++ + + S IP + ++ PCN +N +P CSC DCE+SC Y++Y + M I F+ G +F+ ++ K+ R + D D+ S + + S I+ G D+ L FF RWGT CA+ P V+FL L +GL GI ++ VTTDP+ELWA+PQSRSR EK++FD+ F PFYR Q+II + L + G+ FGP+F+ FL + +LQ+EI++I T +N L +IC PLT T++ C IQ++W YWQD + D + +D N YLDHFI+CS+N + C++ G PI+P +GGFLS D NP Y +A AV++T L+NNY+ S KLH AMEWEK++IEF+ W + + MDIAFTSERSI DE+++E+ D+ TI +SY+IMF YI +SLG +C R LI+SKITL +GGVL+V+ SV SVG+FGFI PATLII E+IPFLVLA G DNIF+LVQ QR E+ E+IGRI+G V PSMLLTS +ES CFFLG +S MPAV+AFALYAGMALL+DF +Q+TCF+SL+ALD RQ N D+ ++ G
Sbjct: 222 YVPFQITYINTDEPIDSFIP-----VDPKVTPCNKALNKNTPACSCVDCEASCPVPPPVPPLPRPSTIFGYDSYAV-----IMLITFICGSTLFILSIVCFSNRKQIVARGEEVGRQVGRRLAAGLHHPGDGARIALAADQEDSPLQSKRSSVISADDLPSGFDDEEQSTFIERLGAGTDKLLAEFFCRWGTACASRPWFVLFLGFLFIIGLGHGIKYIHVTTDPVELWAAPQSRSRVEKEYFDQHFEPFYRTEQIIITSVGLPNIIHNTSNGQIT-FGPVFND-TFLKTVYKLQEEIKQITTPNNYTL-ANICFAPLTSPFTGPLTASQCVIQSIWGYWQDSIETFDFSTTDDD-NFTVNYLDHFIVCSQN--------AYNPECLAPYGGPIEPAVAVGGFLS-PGQDLHNPSYEKATAVILTILVNNYHNKS-------KLHPAMEWEKSYIEFMKNWTTT-KKPEFMDIAFTSERSIEDELNRESQSDVLTILVSYIIMFAYIAISLGQIKNCSRLLIDSKITLGLGGVLLVLASVVCSVGLFGFIGIPATLIIIEVIPFLVLAVGVDNIFILVQTHQRESRRPNESIPEHIGRILGQVGPSMLLTSVSESCCFFLGGLSDMPAVKAFALYAGMALLVDFVLQVTCFVSLLALDTIRQANNKLDVCCFVHG 865 HSP 2 Score: 219.935 bits (559), Expect = 7.990e-58 Identity = 116/244 (47.54%), Postives = 155/244 (63.52%), Query Frame = 0
Query: 701 LNICQKCPNSDDATDENKLG---PMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVT--NENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
L C C N++G P F RY+S+FL+DNP C KAGHAAY + Y+ V AS FM +HTILK+S DYYE++R +R +++ I N IN + ++N VFPYSIFYVFYEQYLTMW DT+ S+ IS I+IF VTF G ++ SS+++++TI MI N+ G+MY W+I+LNA+SLVNLVMA+GI++EFCSH V F RV+R L N+GSS+
Sbjct: 1034 LKYCSSC-----NITRNEIGRPIPTDFDRYVSFFLQDNPDDTCAKAGHAAYGHGV-----NYVTDPTTGLSKVGASYFMAYHTILKTSADYYESMRAARTVSANITNMINDYLKSIDDNSTVEVFPYSIFYVFYEQYLTMWPDTLYSIGISLIAIFAVTFFLMGLDIFSSVVVVITITMIVVNIGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSVKTTRVERVADALTNMGSSI 1267
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: EAA12360.4 (AGAP008137-PA [Anopheles gambiae str. PEST]) HSP 1 Score: 465.692 bits (1197), Expect = 2.994e-145 Identity = 267/641 (41.65%), Postives = 372/641 (58.03%), Query Frame = 0
Query: 1 MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGS---SKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIET-------QDNKVLLKDICHTPLT----PT-SNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
++ PFQID+V +I + + N I PC+ +++ +P CSC DCE+SC + + + L +G + + E +R + + +F R + A E FFT WGT CA +P V+ +L + + GI +LRVTT+P+ELWASP SRSR E+++FD F PFYRI Q+IIKA+N+S + G +FGP+F++ +FLL + LQ++I+KI+ + ++LKDIC PL+ PT + C +Q+LW Y+ DD + D YLD I C N + A C++ G PI P LGG ++D Y +A+AV++TFL+ NY+ + KL A+ WE ++ F+ W + ++M IAFTSERSI DE+++E+ D++TI +SY+IMF YI +SLG R LI+SK+TL +GGV IV+ SV ASVGIFG+I PATLII E+IPFLVLA G DNIF+LVQ QR + TETH E+IGRI+G V PS+LLTS +ES CFFLG +S MPAVRAFALYAGMALLIDF +QITCF+SL+ALD RQ +N D+ ++RG
Sbjct: 98 LYVPFQIDYVAHSSPNETIDGYLPW-NPRIVPCSEKLDANTPACSCVDCEASCPKPPAPPGPPQPFVIYGMDGYAVVMFVVFVVCSGLFLIGACFCATWDGEQELRPHPSGVGAADDDDDESGYFERLGAKTETALEH-------FFTAWGTTCAKHPWLVLLGGLLFIVAMGMGINFLRVTTNPVELWASPYSRSRVEREYFDSNFEPFYRIEQIIIKAENISNVMHNTSNG-VIQFGPVFNR-QFLLDVFELQEQIKKIQAVAVDGSGHNETIMLKDICFAPLSTGAGPTDTQECVVQSLWGYFSDDMDNFNDE-EEDAQGFVINYLDKLIQCFGNYYNPA--------CLAPYGGPIDPAIALGGIPQPKSAD-EKASYAEASAVILTFLVRNYH-------DKNKLQSALAWETEYVRFMQNWTR-----ENMSIAFTSERSIEDELARESQSDVSTILVSYIIMFAYIAISLGHVNQWNRALIDSKVTLGLGGVAIVLASVVASVGIFGYIGVPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDTKKPTETHAEHIGRILGRVGPSILLTSVSESCCFFLGGLSDMPAVRAFALYAGMALLIDFILQITCFVSLLALDTIRQTDNRLDVLCFLRG 706 HSP 2 Score: 228.409 bits (581), Expect = 1.113e-60 Identity = 139/336 (41.37%), Postives = 190/336 (56.55%), Query Frame = 0
Query: 625 GPPTYIELSNRXXXXXXYTLLNNEE-------------ETDEEIRFLKKREKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKA--KRELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNEN------QKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
GPP Y + N Y+ +N++ T I + + YL D Y W S+ K N + + + C C S T + + +FR+Y+S+FLEDNP C KAGHAAY +K R D DV AS FM +HTILKSS DYYEALR +R++++ I + I+ N+ + Q+ VFPYS+FYVFYEQYLTMW DT+KS+ IS ++IFIVTF+ GF++ SSL++++TI MI N+ G+MY W+ISLNA+SLVNLVMA+GIS+EFCSH V F R +R+ L +GSS+
Sbjct: 789 GPPVYFVVKN----GLNYSTMNDQNLICGGQYCNLDSLSTQLYIASKQPQSTYLARPASSWLDDYIDW----SAAPGCCKQWNNGSFCPHQKSACGACNIS--MTAQKRPVESSFRQYVSFFLEDNPDEACAKAGHAAYGSG--VKYRP--DALAPLYNDVGASYFMAYHTILKSSSDYYEALRSARKISANITSTIHANLRLQGRSEADIQQIEVFPYSVFYVFYEQYLTMWPDTLKSMGISVLAIFIVTFLLMGFDIHSSLVVVITITMIVINIGGLMYHWSISLNAVSLVNLVMAVGISVEFCSHLVHSFAMSVEETREKRAADALTKMGSSV 1110
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: AHN54311.1 (Niemann-Pick type C-1a, isoform G [Drosophila melanogaster]) HSP 1 Score: 464.537 bits (1194), Expect = 4.579e-144 Identity = 267/630 (42.38%), Postives = 379/630 (60.16%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSN-----ACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+ PFQI ++ K S + N PCN V+ K P CSC+DC+ SC Q + + L+ MA +FL+G L+F+ + + F ++ + + D D++D + +S + + G + +L FFT+WGT+ A+ P + + + L GI ++ +TTDP++LWASP S+SR E++FFD F PFYR+ Q+IIKA NL + G FGP+F + EFL +L LQ+ I++I N LKDIC+ PL+ + C +Q++W Y+ DD + LD +++ N TYLD C NP C++ G P+ P LGGFL + K+ ANA+++TFL+ N++ + L A+ WEK F+EF+ + +N +++MDIAFTSERSI DE+++E+ D+ TI +SYLIMF+YI +SLG KR I+SKITL IGGV+IV+ SV +SVG+FG+I PATLII E+IPFLVLA G DNIF+LVQ QR + ET ++ +GRI+G V PSMLLTS +ES CFFLG +S MPAVRAFALYAG+AL+IDF +QITCF+SL LD R+ EN DI +I+G
Sbjct: 205 YVPFQITYIQHEPKSNS--NNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCP-QGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFL--MGSFLFTQDDNFQVDGNDVSD----EMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGPYT-FGPVFDR-EFLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDD--HDEDNGFNVTYLDALYDCISNPYL----------CLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKT-------DLENALTWEKKFVEFMTNYTKN-NMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKG 801 HSP 2 Score: 216.853 bits (551), Expect = 7.226e-57 Identity = 120/286 (41.96%), Postives = 170/286 (59.44%), Query Frame = 0
Query: 662 EKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGP--MAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAI-NRNVTNENQKA-----RVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
+ Y+ D Y W SS K + C +C + T + L P F +YL +FL+DNP C KAGHAAY ++ + ++ AS FM +HTILKSS DY+ AL +R++++ I + R ++N A VFPYS+FYVFYEQYLTMW DT++S+ IS +SIF+VTF+ GF++ S+L++++TI MI NL G+MY WNISLNA+SLVNLVMA+GIS+EFCSH V F + V+++ R+ +L +GSS+
Sbjct: 929 QTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCPHQDTSCLRC----NITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAYGGAVRYS-------NSHERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADSLSKMGSSI 1203
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: AHN54310.1 (Niemann-Pick type C-1a, isoform F [Drosophila melanogaster]) HSP 1 Score: 464.537 bits (1194), Expect = 4.579e-144 Identity = 267/630 (42.38%), Postives = 379/630 (60.16%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSN-----ACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+ PFQI ++ K S + N PCN V+ K P CSC+DC+ SC Q + + L+ MA +FL+G L+F+ + + F ++ + + D D++D + +S + + G + +L FFT+WGT+ A+ P + + + L GI ++ +TTDP++LWASP S+SR E++FFD F PFYR+ Q+IIKA NL + G FGP+F + EFL +L LQ+ I++I N LKDIC+ PL+ + C +Q++W Y+ DD + LD +++ N TYLD C NP C++ G P+ P LGGFL + K+ ANA+++TFL+ N++ + L A+ WEK F+EF+ + +N +++MDIAFTSERSI DE+++E+ D+ TI +SYLIMF+YI +SLG KR I+SKITL IGGV+IV+ SV +SVG+FG+I PATLII E+IPFLVLA G DNIF+LVQ QR + ET ++ +GRI+G V PSMLLTS +ES CFFLG +S MPAVRAFALYAG+AL+IDF +QITCF+SL LD R+ EN DI +I+G
Sbjct: 205 YVPFQITYIQHEPKSNS--NNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCP-QGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFL--MGSFLFTQDDNFQVDGNDVSD----EMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGPYT-FGPVFDR-EFLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDD--HDEDNGFNVTYLDALYDCISNPYL----------CLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKT-------DLENALTWEKKFVEFMTNYTKN-NMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKG 801 HSP 2 Score: 216.853 bits (551), Expect = 7.226e-57 Identity = 120/286 (41.96%), Postives = 170/286 (59.44%), Query Frame = 0
Query: 662 EKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGP--MAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAI-NRNVTNENQKA-----RVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
+ Y+ D Y W SS K + C +C + T + L P F +YL +FL+DNP C KAGHAAY ++ + ++ AS FM +HTILKSS DY+ AL +R++++ I + R ++N A VFPYS+FYVFYEQYLTMW DT++S+ IS +SIF+VTF+ GF++ S+L++++TI MI NL G+MY WNISLNA+SLVNLVMA+GIS+EFCSH V F + V+++ R+ +L +GSS+
Sbjct: 929 QTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCPHQDTSCLRC----NITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAYGGAVRYS-------NSHERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADSLSKMGSSI 1203
BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Match: AHN54309.1 (Niemann-Pick type C-1a, isoform E [Drosophila melanogaster]) HSP 1 Score: 464.537 bits (1194), Expect = 4.579e-144 Identity = 267/630 (42.38%), Postives = 379/630 (60.16%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSN-----ACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
+ PFQI ++ K S + N PCN V+ K P CSC+DC+ SC Q + + L+ MA +FL+G L+F+ + + F ++ + + D D++D + +S + + G + +L FFT+WGT+ A+ P + + + L GI ++ +TTDP++LWASP S+SR E++FFD F PFYR+ Q+IIKA NL + G FGP+F + EFL +L LQ+ I++I N LKDIC+ PL+ + C +Q++W Y+ DD + LD +++ N TYLD C NP C++ G P+ P LGGFL + K+ ANA+++TFL+ N++ + L A+ WEK F+EF+ + +N +++MDIAFTSERSI DE+++E+ D+ TI +SYLIMF+YI +SLG KR I+SKITL IGGV+IV+ SV +SVG+FG+I PATLII E+IPFLVLA G DNIF+LVQ QR + ET ++ +GRI+G V PSMLLTS +ES CFFLG +S MPAVRAFALYAG+AL+IDF +QITCF+SL LD R+ EN DI +I+G
Sbjct: 205 YVPFQITYIQHEPKSNS--NNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCP-QGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFL--MGSFLFTQDDNFQVDGNDVSD----EMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGPYT-FGPVFDR-EFLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDD--HDEDNGFNVTYLDALYDCISNPYL----------CLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKT-------DLENALTWEKKFVEFMTNYTKN-NMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKG 801 HSP 2 Score: 216.853 bits (551), Expect = 7.226e-57 Identity = 120/286 (41.96%), Postives = 170/286 (59.44%), Query Frame = 0
Query: 662 EKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGP--MAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAI-NRNVTNENQKA-----RVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
+ Y+ D Y W SS K + C +C + T + L P F +YL +FL+DNP C KAGHAAY ++ + ++ AS FM +HTILKSS DY+ AL +R++++ I + R ++N A VFPYS+FYVFYEQYLTMW DT++S+ IS +SIF+VTF+ GF++ S+L++++TI MI NL G+MY WNISLNA+SLVNLVMA+GIS+EFCSH V F + V+++ R+ +L +GSS+
Sbjct: 929 QTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCPHQDTSCLRC----NITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAYGGAVRYS-------NSHERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADSLSKMGSSI 1203
BLAST of EMLSAG00000008403 vs. nr
Match: gi|565316423|gb|ETE68091.1| (Niemann-Pick C1 protein, partial [Ophiophagus hannah]) HSP 1 Score: 538.88 bits (1387), Expect = 2.995e-170 Identity = 337/918 (36.71%), Postives = 502/918 (54.68%), Query Frame = 0
Query: 41 SPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGF----LIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLF-GETKEFGPIFHKYEFLLPLLRLQKEIEKIET--QDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYL------DHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPTYIELSNRXXXXXXYTLLNNEEETDEEI----RFLK-KREKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSL-YIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
PCSC DC C + L + +M +I I + LIF VV ++ ++ T ++ + ++NS +N + FT WG FC P PVI S+++ +G+ +L++TT+P++LW++P S++R+EK++FD FGPF+R Q+II+A N + ++ + G FGP K+ L +L LQ IE I Q+ V+LKD C PL P +N C I ++ +Y+Q+ LD +N D Y HF+ C R P S T + Q C+ G P+ P+ VLGG+ N Y+ A A+VITF + NY D ++M K+ + WEK F+ F+ + NP+ + I+F++ERSI DEI++E+ D++T+ ISY +MFVYI+++LG S RFL++SKI+L I G+LIV+ SV S+GIF + P TLI+ E+IPFLVLA G DNIF++VQ QR ET + IGRI+G+V PSM L+SF+E+ FFLG++S MPAVR F+L+A +A+ IDF +QITCF+SL+ LD+ RQ +I ++ I + N+ L +E I R LK +R + Y+ D Y W SS + + + + C T E K P GHAAYS ++ +I + ++ A+ FMT+HT+L +S D+ +AL+ +R +A+ I A+ ++ + A VFPYS+FYVFYEQYLT+ DTI +L +S SIFIV+ + GFE+ +++I+ TI MI N+ G+M+LW ISLNA+SLVNLVM+ GIS+EFCSH + F RV+R+E L +GS +
Sbjct: 265 GPCSCQDCSLVCGPKPEPLPPPAPW-----LLLGLDAMCVIMWISYTAFLLIFFAVVCGVWCYRKRYFVSEYTPIDGN------IAYSVNSHQNT---------VTFTSWGAFCVRNPRPVILFSLVIIAMCSSGLAFLKITTNPVDLWSAPNSQARREKEYFDTNFGPFFRTEQLIIQAVNTTPEIFKPVLPGPDIPFGPPLTKH-ILHQVLDLQNGIENITASYQNETVMLKDFCLAPLAPYNNNCTILSVLNYYQNSHSVLD-------SNSTDGYFIIADFHTHFLYCVRAPASLNDTTQLHQPCLGTFGGPVFPWLVLGGY--------DNENYNNATALVITFPVMNY---YNDTEKMMKV---LAWEKEFLNFVKNY-DNPD----LIISFSAERSIEDEINRESNSDVHTVVISYTVMFVYISIALGHIKSVDRFLVDSKISLGIAGILIVLSSVACSLGIFSYFGVPLTLIVIEVIPFLVLAVGVDNIFIIVQTFQRDERLQDETLDKQIGRILGEVAPSMFLSSFSETVAFFLGSLSAMPAVRTFSLFAAVAVFIDFLLQITCFVSLLGLDVKRQ-----EISIFVGVLSFSIAVVNKVEIGLDQRLSMPDEWDVTTILWYSRCLKQQRLAAIGYAPSSWIDDYFDWIKPQSSCCRTYNTTGAFCNASV-VNPSCVRCRPLTKEGKQRP---------------------EGHAAYSSAVNFIPNSS----------EIGATYFMTYHTVLNTSADFIDALKKARIIANNITEAM----VHKEKNAEVFPYSLFYVFYEQYLTIVDDTIFNLGVSLGSIFIVSVVLLGFEVWAAIIVSFTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHVTRAFTISTKARRVERAEEALSQMGSCV 1094
BLAST of EMLSAG00000008403 vs. nr
Match: gi|831217209|ref|XP_012657471.1| (PREDICTED: Niemann-Pick C1 protein [Otolemur garnettii]) HSP 1 Score: 526.939 bits (1356), Expect = 1.126e-165 Identity = 349/969 (36.02%), Postives = 512/969 (52.84%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNG-KSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVIT------SRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDL-FGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK--VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLG-----AISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIR-GPPTYIELSNRXXXXXXYTLLN-----------NEEETDEEIRFLKKREKY--LMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
PF I VFS D A E M N + CN V+ PCSC DC ++C + + + + L+ M I ++ L+F G F+ E++ + GS K + G + L FTRWG+FC P VIF S++ +G+ ++RVTT+P++LW++P+S++R EK++FD+ FGPF+R Q+II+A +T YE G FGP + E L +L LQ IE I N V L+DIC PL+P + C I ++ +Y+Q+ LD +D + D Y HF+ C R P S + + C+ G P+ P+ VLGG+ N Y+ A A+VITF +NNY + KL A WEK FI+F+ + +NP ++ I+F++ERSI DEI++E+ D+ TI ISY +MFVYI+L+LG SC R L++SK++L I G+LIV+ SV S+GIF +I P TLI+ E+IPFLVLA G DNIF+LVQ QR ET + +GR++G+V PSM L+SF+E+ FFLG + + M AV L +A+L + + ++S+ D + + F I ++ GPP Y L YT L N + ++I + + Y + ++ D Y W SS + + + C T E K P F R+L FL DNP C K GHAAYS ++ I + V A+ FMT+HT+L++S D+ +A++ +R +AS I + N RVFPYS+FYVFYEQYLT+ DTI +L +S ++F+V + G EL S++++ TI M+ N+ G+M+LW ISLNA+SLVNLVM+ GIS+EFCSH + F +RV R+E L ++GSS+
Sbjct: 200 QAPFTITPVFS-DLPAHGMEPM---NNATKGCNESVDEVTGPCSCQDCSATCGPKPQP-PPPPVPWRLFGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSSIAFSVNGSDKG----EASCCDPVGAAFEGCLRHLFTRWGSFCVRNPGCVIFFSLVFITTCSSGLVFIRVTTNPVDLWSAPRSQARLEKEYFDQHFGPFFRTEQLIIRAPLTNTHTYEPYPSGADVPFGPPLN-VEILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSVLDHKIGDDFFVYAD-YHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDEN--------YNNATALVITFPVNNYYN------DTEKLQRAQAWEKEFIDFVKNY-KNP----NLTISFSAERSIEDEINRESNSDLFTIVISYAVMFVYISLALGHIKSCHRLLVDSKVSLGIAGILIVLSSVTCSLGIFSYIGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETIAFFLGNYALNSTNPMIAVFVGVLSFSVAVLNKVEIGLDQYLSMP--DDSYVVDYFKSISQYLHAGPPVYFVLEE----GHNYTSLQGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVYNTTEQFCNASV-VDPACVRCRPLTPEGKQRPQGEDFMRFLPMFLADNPNPKCGKGGHAAYSSAVNILSN---------DTGVGATYFMTYHTVLQTSADFIDAMKKARLIASNITETMGIN----GSGYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAVFLVAVVLLGCELWSAVLMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSTKGSRVARAEEALAHMGSSV 1118
BLAST of EMLSAG00000008403 vs. nr
Match: gi|926614579|ref|XP_013772339.1| (PREDICTED: Niemann-Pick C1 protein-like [Limulus polyphemus]) HSP 1 Score: 513.072 bits (1320), Expect = 3.386e-159 Identity = 344/880 (39.09%), Postives = 508/880 (57.73%), Query Frame = 0
Query: 122 SRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTG-IFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYE-DLFGETK-EFGPIFHKYEFLLPLLRLQKEIEK-IETQDNK-VLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIP-IKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITC--------------------FISLMAL----------DIARQRENFW-DIF-----YWIRGPPTYIELSNRXXXXXXYTLLNNEEETDEEIRFL-----KKREKYLMYSG-----DRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCP----NSDDATDEN--KLGPMA----FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
S I+ + G + L F+RWG F A +P+ VIFL+++++L L G +F +VTTDP++LW S S++R++ ++F++ FGPFYR+ Q+II N +F E D G + +GP+F K EFLL +L LQ+++E + ++D K + L DIC PL P + AC +Q++++Y+ K+G + + D YL H + C+ N + C++ G P I P GGF N H A+A+VITF +NNYN DP + A+ WE F+ F+ + ++ +M++AF +ERSI DE+ + + DI T+ ISY+IMF YI ++LG+ SCK L++SKI+L + GV+IV++SV +S+GIF F+ PATLII E+IPFLVLA G DN+F+LVQ QR ET QE IGR+VG+V PSM+L+S + S+CFF+GA++ MPAV+ FALYAG+AL+I+FF+Q+TC F S MA+ D++ +++ D F Y GPP Y +++ N + + + R + +L G ++ + P + L D +KS+ ++ CP N+DD E+ KL + F YL +FL+D P C KAG A +S ++ L D V A+++MT+HTILK+SKD+Y+AL +SR ++ ++ I + T + RVFPYSI +VFYEQYLTMW DT+KSL S +IFIVTF+ G + S+ II++TIVMI NLMG+MY WNISLNA+SLVNLV+A+GIS+EFCSH + F R +R++ L IGSS+
Sbjct: 413 SDDISCFEKLGAITERILESLFSRWGMFVANHPLSVIFLALIVSLLLGLGLVFSFKVTTDPVDLWVSHNSQARKDMEYFNKHFGPFYRVEQIIITPTNNESFVAEADKDGISNYTWGPVFRK-EFLLEVLDLQRKVESLVISKDGKNISLPDICLAPLAPENKACVVQSVFAYFH----SFFKSG---EASLPDNYLSHILDCTSN--------GYQFHCLAPYGGPLIPPAVAFGGF--------ENNTLHTASALVITFPVNNYN----DPDLNKD---ALAWENLFVNFMKNF-----SSPNMNVAFKAERSIEDELERGSHSDIITVAISYVIMFAYIAIALGEVKSCKSILVDSKISLGLAGVVIVLLSVISSLGIFCFVGVPATLIIIEVIPFLVLAVGVDNVFILVQAYQRDERLPHETMQEEIGRVVGEVAPSMMLSSLSMSSCFFIGALTEMPAVKLFALYAGVALIINFFLQMTCFLGLFILDAKRQELLAFLAWFCSSMAVIDKIDIGFDQDLSMPEDSYMLDYFKYLYQYLSVGPPVYFVITDGY----------NYSDIEHQNRLCALPSCRNDSLFLQIKGAADISEKTYIAAQP-ASWLDDYLDYMKSRQCCFEQHNK--TFCPSYAANNDDLECESCAKLQMRSVGSEFNHYLEYFLQDLPNEYCAKAGKAQFSSAVQ------LISDSNNSVRVGATHYMTYHTILKTSKDFYKALELSRYISEKLTEQIRTDSTESD--LRVFPYSIVHVFYEQYLTMWPDTLKSLGFSLAAIFIVTFLLLGLDFFSAAIIVITIVMIIINLMGLMYWWNISLNAVSLVNLVVAVGISVEFCSHLTRLFAISPARTRTKRAQDALERIGSSI 1235
BLAST of EMLSAG00000008403 vs. nr
Match: gi|970895596|ref|XP_015113280.1| (PREDICTED: Niemann-Pick C1 protein isoform X4 [Diachasma alloeum]) HSP 1 Score: 504.212 bits (1297), Expect = 5.876e-156 Identity = 281/636 (44.18%), Postives = 383/636 (60.22%), Query Frame = 0
Query: 1 MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGK-SPCSCTDCESSCASQIINDKNHH----LEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLT------PTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
++ PFQI ++ + +K + + + + PC+ N + CSC DCE+SC + Y+ Y + +M IIF++G +F+ ++ K + T +D S T+ I+ G + D++L FF WG FCA PV V+ LS + + L GI + VTTDP+ELWAS SRSR E+ +FD F PFYR Q+II A L + G FGP+FH+ EFL +L LQ+ I+ IET++N L DIC PLT PT C IQ++W YW + K ++T +++ + YLDHF C+ NP + C++ G P++P +GGFL+ S +P Y +A A+V+TFL+NNY+ S KL AMEWEK ++E++ W+ N + +MD+AFTSERSI DE+ +E+ DI+TI +SY+IMF YIT+SLG SC R LI+SKITL +GGVLIV+ SV SVG+FGFI PATLII E+IPFLVLA G DN+F+LVQ QR G E+ E+IGR +G V PSMLLTS +ES CFFLG +S MPAV+AFALYAGMALLIDF +QITCF+SL+ LD R N D+ W+RG
Sbjct: 205 IYVPFQITYIGTDEKVGN----FTPMDPVVTPCSKPFNSTTAACSCVDCEASCPVPPPAPLPPQPFSLIGYDGY-----AVTMIIIFILGTSLFLLSIVCFSNRKTIGV----TSADDLPSGLQEEESTV--IEKLGANTDKFLQEFFCAWGVFCAKRPVEVLLLSACIVVVLGCGIRYTHVTTDPVELWASATSRSRVERQYFDSHFEPFYRNEQIIISAVGLPNIIHNTSDGLIT-FGPVFHR-EFLTTILELQEGIKAIETENNYTL-ADICFAPLTNAFTGPPTVGKCTIQSVWGYWSNSMKRFNET--DEEHGYMMNYLDHFKTCTSNPYNP--------DCLAPYGGPVEPAIAVGGFLAPGQS-LKDPHYEKATAIVLTFLVNNYHNKS-------KLQPAMEWEKAYVEYMKDWVAN-KKPSYMDVAFTSERSIEDELYRESQSDISTILVSYIIMFAYITVSLGQMKSCSRLLIDSKITLGLGGVLIVLTSVICSVGLFGFIGLPATLIIIEVIPFLVLAVGVDNVFILVQTHQREGRRPNESIPEHIGRTLGQVGPSMLLTSVSESCCFFLGGLSDMPAVKAFALYAGMALLIDFLLQITCFVSLLTLDTLRHSGNRLDVCCWLRG 803 HSP 2 Score: 227.639 bits (579), Expect = 1.184e-57 Identity = 124/284 (43.66%), Postives = 171/284 (60.21%), Query Frame = 0
Query: 664 YLMYSGDRKFDLYHPWTTGLSSMDDSVK---SKNLKAKRELNICQKCPNSDDATDENKLGP---MAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNV--TNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
Y+ D Y W S D+ K N E +C CP S NK G F +Y+S+FL DNP C KAGHAAY + + K + V AS FMT+H+ILK+S DYYE++R +R++++ I N IN ++ N +++ VFPYS+FYVFYEQYLTMW DT+KSL IS ++IF+VTF G ++ SS ++++TI MI N+ G+MY W+I+LNA+SLVNLVMA+GIS+EFCSH V F R++R + N+GSS+
Sbjct: 934 YVAKPASSWLDDYIDW----SQADNCCKYFPGNNSFCPHEKFMCSNCPQS-----TNKFGRPDRTYFEKYISYFLNDNPNDQCVKAGHAAYGQGVNYKLNPVNNLS-----HVGASYFMTYHSILKTSADYYESMRAARKISANITNMINSHMEAANRSERTEVFPYSVFYVFYEQYLTMWPDTLKSLGISLLAIFLVTFFLMGLDIFSSFVVVITITMIMVNIGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVRATRIERVADAVTNMGSSV 1203
BLAST of EMLSAG00000008403 vs. nr
Match: gi|591350972|ref|XP_007069938.1| (PREDICTED: LOW QUALITY PROTEIN: niemann-Pick C1-like protein 1 [Chelonia mydas]) HSP 1 Score: 499.975 bits (1286), Expect = 1.804e-155 Identity = 323/955 (33.82%), Postives = 519/955 (54.35%), Query Frame = 0
Query: 3 TPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKS-PCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNK----VLLKDICHTPLTP---TSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDT--YLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIF------YWIRGPPTYIELSNRXXXXXXYTLLNNEEETDEEIRFLKKREKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMA--FRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
P +IDF + E + N++ C ++ + CSC DC SC QI + L+ F ++F + ++F G +T R I + K + + + GE F RWGT A++PV VI +S ++ +GL G+ ++++TTDP+ELW+SP S++RQEKDF+D+ FGPF+R QVI+ AK L ++ Y+ L K F I LL LL LQ +++IE K V LKDIC+ PL P ++ C + +L Y+Q++ L+ T + + DHF+ C +P+S T+++ SC++ G+P+ P+ +GG+ T Y +A A+++TF +NNY + A+ WE+ F++ + ++ + +T++ +A+ +ERS+ DEI++ T DI ISYL++F+YI L+LG+ +SCKR L++SK+TL +GGVL+V+ +V +S+G + ++ P++L+I E++PFLVLA G DNIF+ V QR E E ++++GR++G V PSMLL SF+E+TCFFLG+++ MPAVR FAL A +A+L DF +Q++ F++L++LD RQ +++ + Y++ G PTY ++ Y +G GL+ + S N +++ PN + P F +L WFL D P +NCPK G AY ++ L DG ++ AS FM +HT L +S+++ ALR +R+LA+ I +++ R V + RVFPY++ YVFYEQYLT+ + + +L + + F + + G +L S LI L+TIVMI + +G M LW IS NA+SL+NLV A+GIS+EF SH + F R++R++ +N+GS++
Sbjct: 218 APLEIDFQLV-PANGVVGEGIVPLNSKTWRCGTAISDEGEACSCLDCAESC-PQIPTPTLQPPPFKVGSLDGILFVCCLLFCLLTVLF-GAFLTWRCISRPKQAGSEGRQHPRDQPKRSERLSQATHRILGE--------MFRRWGTMVASHPVSVILVSAVVVVGLSCGMVFIQLTTDPVELWSSPDSQARQEKDFYDQNFGPFFRTNQVILTAKGLPSYTYDSLLLGKKNFSGIL-SMAVLLDLLELQTRLQEIEVWSEKDGRNVTLKDICYAPLNPNNASATDCFVNSLVQYFQNNRTRLEMTASQTQGGRTGMVDWRDHFLYCVNSPLSFKDITNLQLSCIADYGVPVFPFLAVGGY--------TGEDYSEAQALILTFSLNNYLR------SQAGYAWALLWEQRFLQVVQEFQR--AHTRNYTVAYMAERSLEDEINRTTAEDIPIFAISYLVIFLYIALALGEYSSCKRILVDSKVTLGLGGVLVVLGAVFSSMGFYAYVGLPSSLVILEVVPFLVLAVGADNIFIFVLEYQRSVREPGERREQHVGRVLGTVAPSMLLCSFSEATCFFLGSLTRMPAVRTFALNAALAVLFDFLLQMSMFVALVSLDARRQEDSYLVQYFQYLNQYFMVGLPTYFVTTS----------------------------GYNFSTGP-----------GLNGVCSSAGCDNNSLTQKIQYATGFPNVCMRNLSEVIRPSVEQFNHFLPWFLHDMPNLNCPKGGLGAYDTAV------KLGPDG----EIQASRFMAYHTPLTNSQEFTAALRAARELATNITHSM-RRVPGTDPSFRVFPYTVTYVFYEQYLTIVSEGLFNLALCLVPTFAICCVLLGMDLRSGLINLLTIVMILVDTVGAMTLWGISYNAVSLINLVTAVGISVEFVSHLTRAFAVSTQPTRLERAKEATINMGSAV 1094
BLAST of EMLSAG00000008403 vs. nr
Match: gi|1130262884|ref|XP_019770256.1| (PREDICTED: Niemann-Pick C1 protein isoform X4 [Dendroctonus ponderosae]) HSP 1 Score: 502.286 bits (1292), Expect = 3.113e-155 Identity = 281/634 (44.32%), Postives = 383/634 (60.41%), Query Frame = 0
Query: 1 MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADC---TDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPL-----TPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
++ PFQI+++ S M + EI PCN +N +P CSC DCE SC + ++ SF M ++F+IG ++F+ +V + F I ++ DM+ + + I+ G + D L FF +WGTFCA P V+F + + L GI +L+VTTDP+ELWASP SRSR EK++FD F PFYR QVII+AKNL + + G FGP F+ FLL +L LQ++I+ I + ++IC PL + + C +Q++W Y+QD + ++TG D + YLD + C NP + C + G P+ P GGFL + +PKY A AV++TFL+NNY+ S K+ AMEWEK F+ F+ + ++ +++MDIAFTSERSI DE+ +E+ GD+ TI ISYLIMF YI +SLG SC R LI+SKITL +GGV+IV+ SV +SVG+FGF+ PATLII E+IPFLVLA G DNIF+LVQ QR + ETH ++IGR +G V PSMLLTS +ES+CFFLG++S MPAVRAFALYAGMALL DF QITCF+SL++LD RQ N +DIF +RG
Sbjct: 213 VYVPFQINYINSTTAKVGNFTPM---DIEITPCNKPLNSDTPACSCVDCEDSCPVPPPD-PPKPQPFHIAGFEGMSFLMLVVFVIGSIVFLLIVFMCSAGRTFGITSELEHEMDMHSVSKVPGEYDTPSSFIERLGANTDSCLQKFFEKWGTFCAERPWLVLFFGTCVIVALGHGIKYLKVTTDPVELWASPSSRSRVEKEYFDSHFDPFYRNEQVIIRAKNLKSIIHPTSLGNVT-FGPAFND-TFLLEVLDLQEKIKAIGGGTDYAY-ENICFAPLRTDEDEASLDQCAVQSVWGYFQDSIETFEETG-TDPDHFQINYLDALLKCMSNPYNT--------DCFALYGGPVDPAIAFGGFLKSGENLPKSPKYEDATAVILTFLVNNYHNKS-------KIVAAMEWEKHFVAFMKNYTES-NVSQYMDIAFTSERSIEDELDRESQGDVITILISYLIMFAYIAVSLGQVNSCSRLLIDSKITLGLGGVIIVLASVVSSVGLFGFVGTPATLIIIEVIPFLVLAVGVDNIFILVQTHQRDVKKPGETHAQHIGRTLGQVGPSMLLTSVSESSCFFLGSLSDMPAVRAFALYAGMALLFDFIFQITCFVSLLSLDTIRQNSNRFDIFCCLRG 822 HSP 2 Score: 217.238 bits (552), Expect = 3.184e-54 Identity = 111/237 (46.84%), Postives = 154/237 (64.98%), Query Frame = 0
Query: 704 CQKCPNS-DDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
CQ C + ++ T K P F RY+S+FL+DNP C KAGHAAYS ++ Y +V AS FM++H+ILK+S DYYE++R +R +++ + ++ VFPYS+FYVFYEQYLTMW DT++SL IS ++IF+ TF G ++ SS+++L+TI MI NL G+MY W+I+LNA+SLVNLVMA+GIS+EFCSH V F RV R+ L +GSS+
Sbjct: 996 CQACGIALNNRTHRPK--PEEFERYISFFLQDNPDATCAKAGHAAYSHAV-----NYASNRKTNLSNVGASYFMSYHSILKTSADYYESMRKARTISANLTKSVG---------VEVFPYSVFYVFYEQYLTMWPDTLQSLGISLLAIFLATFFLMGLDIFSSIVVLITITMILVNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVKTTRVDRAADALAKMGSSI 1216
BLAST of EMLSAG00000008403 vs. nr
Match: gi|642938459|ref|XP_008199812.1| (PREDICTED: Niemann-Pick C1 protein isoform X4 [Tribolium castaneum]) HSP 1 Score: 502.286 bits (1292), Expect = 3.600e-155 Identity = 284/642 (44.24%), Postives = 378/642 (58.88%), Query Frame = 0
Query: 4 PFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTF---FSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNA------CNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPTYIELSNR 635
PFQI+++ S + N EI PCN + KS CSC DCE SC + + F M I+F +G L+F+ VV E + ++ DT S + + + ++ G + D +L FF WGT CA P V+FL + +GL GI +L+VTTDP+ELWASP SRSR EK++FD F PFYR QVIIKA NL + GE FGP F FL +L+LQ+ I+ I D L IC PL C +Q++W Y+Q+D + D+T D YLD+FI C++NP + C++ G P+ P +GGFL + P Y A AV++TFL+NNY+ + KL AMEWEK F+ F+ + + E +M+IAFTSERSI DE+ +E+ D+ TI +SY+IMF YI +SLG +C R LI+SKITL +GGVLIV+ SV +SVG+FGF+ PATLII E+IPFLVLA G DNIF+LVQ QR G + TETH ++IGR +G V PSMLLTS +ES CFFLG++S MPAV+AFALYAGMALL DF +QITCF+SL++LD RQ N +DI +I+G I +N+
Sbjct: 222 PFQINYLNSTGPVDKDGVKYQPLNPEITPCNKAFDSKSAACSCVDCEESCPVPPPQ-PPAPQPFTIAGFDGYFFLMIIVFCVGTLMFLLVVFVCPSRAEIGVTSEMGHELDTHSINKMPGEYESSSSFLEKLGANTDTFLQRFFEWWGTICAERPWLVLFLGACVVVGLGHGIKYLKVTTDPVELWASPTSRSRIEKEYFDSHFEPFYRNEQVIIKAVNLPQIHHNTSNGEVV-FGPAFDA-TFLKEVLKLQERIKAIGA-DTDYALGRICFAPLRSVGKVSTDVEECVVQSIWGYYQNDEETFDETDV-DPDGFETNYLDYFISCAQNPYNP--------KCLAPYGGPVDPAIAMGGFLQPGENLSKQPNYQNATAVILTFLVNNYHNKT-------KLSPAMEWEKAFVAFMKNYTTS-EKPSYMEIAFTSERSIEDELDRESQSDVVTILVSYIIMFAYIAVSLGQVNTCSRLLIDSKITLGLGGVLIVLASVVSSVGLFGFVGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQREGKKPTETHAQHIGRTLGQVGPSMLLTSVSESCCFFLGSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDICCFIKGSKKEIVQTNQ 842 HSP 2 Score: 224.942 bits (572), Expect = 1.064e-56 Identity = 118/278 (42.45%), Postives = 166/278 (59.71%), Query Frame = 0
Query: 664 YLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSL--YIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
Y+ D Y W + K+ C C N ++ P F Y+S+FL+DNP C KAGHAAYS+ + K +L + G AS FM +HTILK+SKDYYE++R +R++++ I N IN + + + VFPYS+FYVFYEQYLTMW DT++S+ IS +IF+VTF+ G + SS ++++TI MI NL G+MY W+I+LNA+SLVNLVMA+GI++EFCSH V F RV+R+ +L +GSS+
Sbjct: 963 YIARPSSSWLDDYIDWAAAAKTCCKYNKTTGAFCPHTKGTCATC-NISYLPLNHRPTPNDFEHYVSFFLQDNPDETCAKAGHAAYSQGVNYATNKTTHLSKVG-------ASYFMAYHTILKTSKDYYESMRSARKVSANITNTINTKI--PSSQIEVFPYSVFYVFYEQYLTMWPDTLQSMAISLAAIFVVTFLLMGLDFFSSAVVVITITMIVVNLGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSLKTTRVERAADSLTRMGSSI 1230
BLAST of EMLSAG00000008403 vs. nr
Match: gi|1004397372|gb|KYB26045.1| (Niemann-Pick C1 protein-like Protein [Tribolium castaneum]) HSP 1 Score: 501.901 bits (1291), Expect = 4.359e-155 Identity = 284/642 (44.24%), Postives = 378/642 (58.88%), Query Frame = 0
Query: 4 PFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTF---FSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNA------CNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPTYIELSNR 635
PFQI+++ S + N EI PCN + KS CSC DCE SC + + F M I+F +G L+F+ VV E + ++ DT S + + + ++ G + D +L FF WGT CA P V+FL + +GL GI +L+VTTDP+ELWASP SRSR EK++FD F PFYR QVIIKA NL + GE FGP F FL +L+LQ+ I+ I D L IC PL C +Q++W Y+Q+D + D+T D YLD+FI C++NP + C++ G P+ P +GGFL + P Y A AV++TFL+NNY+ + KL AMEWEK F+ F+ + + E +M+IAFTSERSI DE+ +E+ D+ TI +SY+IMF YI +SLG +C R LI+SKITL +GGVLIV+ SV +SVG+FGF+ PATLII E+IPFLVLA G DNIF+LVQ QR G + TETH ++IGR +G V PSMLLTS +ES CFFLG++S MPAV+AFALYAGMALL DF +QITCF+SL++LD RQ N +DI +I+G I +N+
Sbjct: 222 PFQINYLNSTGPVDKDGVKYQPLNPEITPCNKAFDSKSAACSCVDCEESCPVPPPQ-PPAPQPFTIAGFDGYFFLMIIVFCVGTLMFLLVVFVCPSRAEIGVTSEMGHELDTHSINKMPGEYESSSSFLEKLGANTDTFLQRFFEWWGTICAERPWLVLFLGACVVVGLGHGIKYLKVTTDPVELWASPTSRSRIEKEYFDSHFEPFYRNEQVIIKAVNLPQIHHNTSNGEVV-FGPAFDA-TFLKEVLKLQERIKAIGA-DTDYALGRICFAPLRSVGKVSTDVEECVVQSIWGYYQNDEETFDETDV-DPDGFETNYLDYFISCAQNPYNP--------KCLAPYGGPVDPAIAMGGFLQPGENLSKQPNYQNATAVILTFLVNNYHNKT-------KLSPAMEWEKAFVAFMKNYTTS-EKPSYMEIAFTSERSIEDELDRESQSDVVTILVSYIIMFAYIAVSLGQVNTCSRLLIDSKITLGLGGVLIVLASVVSSVGLFGFVGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQREGKKPTETHAQHIGRTLGQVGPSMLLTSVSESCCFFLGSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDICCFIKGSKKEIVQTNQ 842 HSP 2 Score: 224.557 bits (571), Expect = 1.439e-56 Identity = 110/221 (49.77%), Postives = 153/221 (69.23%), Query Frame = 0
Query: 721 PMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSL--YIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
P F Y+S+FL+DNP C KAGHAAYS+ + K +L + G AS FM +HTILK+SKDYYE++R +R++++ I N IN + + + VFPYS+FYVFYEQYLTMW DT++S+ IS +IF+VTF+ G + SS ++++TI MI NL G+MY W+I+LNA+SLVNLVMA+GI++EFCSH V F RV+R+ +L +GSS+
Sbjct: 1019 PNDFEHYVSFFLQDNPDETCAKAGHAAYSQGVNYATNKTTHLSKVG-------ASYFMAYHTILKTSKDYYESMRSARKVSANITNTINTKI--PSSQIEVFPYSVFYVFYEQYLTMWPDTLQSMAISLAAIFVVTFLLMGLDFFSSAVVVITITMIVVNLGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSLKTTRVERAADSLTRMGSSI 1230
BLAST of EMLSAG00000008403 vs. nr
Match: gi|755989663|ref|XP_011312258.1| (PREDICTED: Niemann-Pick C1 protein isoform X4 [Fopius arisanus]) HSP 1 Score: 499.975 bits (1286), Expect = 2.315e-154 Identity = 281/636 (44.18%), Postives = 382/636 (60.06%), Query Frame = 0
Query: 1 MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGK-SPCSCTDCESSCASQIINDKNHH----LEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLT------PTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
++ PFQID++ S +K + + + +I PC+ N + CSC DCE SC + ++ Y + +M I F++G +F+ ++ K+ + T +D + T+ ++ G + D++L FF WGTFCA +PV V+ + + + L GI + VTTDP+ELWAS SR+R E+ +FD F PFYR Q+II A L + G FGP+FH+ EFL +L LQ++I+ I+T+ N L DIC PLT PT C IQ++W YW + K +KT + + TYLDHF C+ NP + C++ G PI+P +GGFL S +P Y +A A+V+TFL+NNY+ S KL AMEWEK++IE++ W + +MD+AFTSERSI DE+ +E+ DI+TI +SY+IMF YIT+SLG SC R LI+SKITL +GGVLIV+ SV SVG+FGFI PATLII E+IPFLVLA G DN+F+LVQ QR G E+ E+IGR +G V PSMLLTS +ES CFFLG +S MPAV+AFALYAGMALL DF +QITCF+SL+ LD R N +DI WIRG
Sbjct: 204 IYVPFQIDYIGSDEKVGN----FTPLDPDITPCSKPYNSTTAACSCVDCEESCPVPPPAPLPPQPFTLIGHDGY-----AVTMIITFIMGTSLFLLSIVCFTNRKKIGV----TSADDLPNGLQEEESTV--VEKLGANTDKFLQEFFCAWGTFCAKHPVEVLLVGACIIVVLGCGIRYTHVTTDPVELWASATSRARMERQYFDSHFEPFYRNEQIIISAVGLPNIIHNTSDGLIT-FGPVFHR-EFLTTILELQEDIKAIKTESNYTL-ADICFAPLTNSFTVAPTVEKCTIQSVWGYWGNSMKRFNKT--IKEHGYVTTYLDHFKTCTSNPYNS--------ECLAPYGGPIEPAIAVGGFLKPGQS-LKDPHYEKATAIVLTFLVNNYHNKS-------KLQPAMEWEKSYIEYMKHWAAT-KKPIYMDVAFTSERSIEDELYRESQSDISTILVSYIIMFAYITVSLGQMKSCGRLLIDSKITLGLGGVLIVLTSVICSVGLFGFIGLPATLIIIEVIPFLVLAVGVDNVFILVQTHQREGRRPNESIPEHIGRTLGQVGPSMLLTSVSESCCFFLGGLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLTLDTLRHSGNRFDICCWIRG 802 HSP 2 Score: 224.172 bits (570), Expect = 1.873e-56 Identity = 112/241 (46.47%), Postives = 159/241 (65.98%), Query Frame = 0
Query: 704 CQKCPNSDDATDENKLG---PMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNV--TNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
C CP NK G ++F +Y+S+FL DNP C KAGHAAY + + + + V AS FMT+H+ILK+S DYYE++R +R++++ I N IN ++ N ++ VFPYS+FYVFYEQYLTMW DT+KSL IS ++IF+VT+ G ++ SS ++++TI MI N+ G+MY W+I+LNA+SLVNLVMA+GIS+EFCSH V F R++R + N+GSS+
Sbjct: 972 CLNCPKR-----TNKFGRPDQVSFEKYVSYFLNDNPNDQCVKAGHAAYGQGVNYQLNPTTNLS-----HVGASYFMTYHSILKTSADYYESMRAARKISANITNMINSHLEAANRTERTEVFPYSVFYVFYEQYLTMWPDTLKSLGISLLAIFLVTYFLMGLDIFSSFVVVITITMILVNIGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVRATRIERVADAVTNMGSSV 1202
BLAST of EMLSAG00000008403 vs. nr
Match: gi|939687057|ref|XP_014300207.1| (PREDICTED: Niemann-Pick C1 protein isoform X4 [Microplitis demolitor]) HSP 1 Score: 498.434 bits (1282), Expect = 9.120e-154 Identity = 282/632 (44.62%), Postives = 378/632 (59.81%), Query Frame = 0
Query: 1 MHTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSP-CSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLT------PTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625
++ PFQI++ + K + + E+ PC+ +N SP CSC DCESSC + + + M IIF+ G +F+ VI K+ + +D + TI I+ G + D++L FF +WGT CA P V+ + + L TGI +++TTDP+ELWASP SRSR E+ +FD F PFYRI Q+II NL + G FGP+F FL + LQ+ I+ I T++N L DIC PLT PT + C IQ++W YW+D+ E +K+ D + + YLDHF C NP + C++ G P+ P LGGFLS S +P YH A A+V++ L+NNY+ + KL AMEWE++FI F+ W++N + +MDIAFTSERSI DE+ +E+ DI+TI +SY+IMF YI +SLG SC+R L++SKITL +GGV IV+ SV SVGIFGFI PATLII E+IPFLVLA G DN+F+LVQ QR G E+ E+IGR +G V PSMLLTS +ES CFFLG +S MPAV+AFALYAGMALLIDF +QITCF+SL+ LD RQ N +D+ W+RG
Sbjct: 211 LYVPFQINYNATDTKYG----PYTPLDPEVTPCSQALNEHSPACSCVDCESSCPVPPPA-PPLPKPFTLIGYDGIAVIMTIIFIGGSTLFLMSVICFSNRKQIGV----VSADDLPNGLDDQQSTI--IERLGANTDKFLQEFFCKWGTVCAKQPWTVLLCGFITVVALGTGITCMQMTTDPVELWASPLSRSRIERTYFDSHFEPFYRIEQLIITPVNLPKIIHNTTNGPII-FGPVFDA-NFLRSVHSLQEAIKNITTKNNYTL-ADICFAPLTNDFTGPPTVDKCTIQSIWGYWKDNVAEFNKSSIED--GYLENYLDHFQKCVGNPTNP--------ECLASYGGPVLPAVALGGFLSQGQS-LRDPAYHNATALVVSILVNNYHNKT-------KLIPAMEWEESFINFMKDWVKN-KKPSNMDIAFTSERSIEDELKRESQSDISTILVSYIIMFAYIAISLGQMRSCERLLVDSKITLGLGGVFIVLASVVCSVGIFGFIGLPATLIIIEVIPFLVLAVGVDNVFILVQTHQREGRRPNESIPEHIGRTLGQVGPSMLLTSVSESCCFFLGGLSDMPAVKAFALYAGMALLIDFILQITCFVSLLTLDTVRQSANRFDVCCWMRG 809 HSP 2 Score: 208.764 bits (530), Expect = 1.502e-51 Identity = 111/243 (45.68%), Postives = 162/243 (66.67%), Query Frame = 0
Query: 707 CPNSDDAT-----DENKLG---PMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNV--TNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
CP+ + NK G F++Y+S+FLEDNP C KAGHAAY + + Y+ +V A+ FM +H+ILK+S+DYYE+++ +R++A+ I +N N+ + + VFPYS+FYVFYEQYLTMW DT+KS+ IS ++IFIVTF+ G ++ SS+++++TI MI N+ G+MY W+I+LNA+SLVNLVMA+GIS+EFCSH V F R++R E + N+GSS+
Sbjct: 972 CPHQNSGCLSCDIGSNKYGRPDSTEFKKYVSYFLEDNPDEGCAKAGHAAYGQGV-----NYVMDKSSKLSEVKATYFMAYHSILKTSEDYYESMKAARKIAANISEMLNDNLRKVSITDRVDVFPYSVFYVFYEQYLTMWPDTLKSIGISLVAIFIVTFLLMGLDIFSSIVVIITITMILVNIGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSTSVKETRIERVEDAVTNMGSSI 1209
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold609_size125094-snap-gene-0.22 (protein:Tk01016 transcript:maker-scaffold609_size125094-snap-gene-0.22-mRNA-1 annotation:"niemann-pick c1 isoform x7") HSP 1 Score: 618.616 bits (1594), Expect = 0.000e+0 Identity = 311/624 (49.84%), Postives = 424/624 (67.95%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCNIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSR-TINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQ----SCMSKGGIPIKPYFVLGGFLSGNASDF-TNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDI 619
++PF I FV S ++ + +N + PCN GK CSCTDC +C + + + +L+ +F M +IF++G ++F+ +V T++ ++ D T +++ S+T +N I G L + F RWGTFCA YPVPVI V+ AL LC+G+ WL++TTDP+ELWA+P SRSR EK++FD TF PFYR AQVI AKNL F+Y D G + FGP+FH EFL PLLRLQ+ I+ I T + + L+D+C+ PL+P N CNIQN+W+YWQD + D ++ T +N TYLDHF+ C+RNP A T Q CMSKGGIP++P+FVLGGF+ S N Y + AVV++ +++N++ YS D + +L A EWEK FIEF+ +W +NP+NT++MD+AF SERSI DE++++T GD+ TI ISY IMFVYIT++LG TS + ++ESKITL I GVL+V++SVGAS+GIFGF + +TLIIFEIIPFLVLA G DNIF+LVQ QR + ET E++GR+VG+V PSMLL+S +E+TCFFLGA++ MPAV +FAL AGMA+LIDFFMQITCF+SL ALD+ RQ + +DI
Sbjct: 805 YSPFDILFVISDEETL---DGFEMHNPTVVPCNESSMGKPQCSCTDCLDTCTPVVFEEPTELFKVG--KLDGVAFIMILIFILGTVLFLALVFTNKLVQ---TTDDDTSLDEEPISQTPHGPPKLNVIDRMGVKLILTMERLFARWGTFCAYYPVPVIVFGVVAALILCSGVQWLKITTDPVELWAAPGSRSRSEKEYFDSTFRPFYRTAQVIAAAKNLPDFEYTDADGIEQTFGPVFHADEFLKPLLRLQEAIQNITTA-SGLKLQDVCNAPLSPQDNVCNIQNVWAYWQDSEENFDLIRFDANTGNNLTYLDHFLTCARNP---ALPTDGNQVNPLGCMSKGGIPVQPFFVLGGFIPEGVSGLPQNANYQGSKAVVMSIIVDNFDMYSTDHESQLRLTKAKEWEKAFIEFMKEWEKNPDNTQYMDVAFNSERSIEDELARQTQGDVKTIVISYAIMFVYITIALGQFTSFRTIMVESKITLGISGVLLVLLSVGASIGIFGFANIESTLIIFEIIPFLVLAVGVDNIFILVQTYQRSERKPYETLPEHVGRVVGEVGPSMLLSSLSEATCFFLGALTDMPAVYSFALNAGMAILIDFFMQITCFVSLTALDMYRQESHRYDI 1416 HSP 2 Score: 233.417 bits (594), Expect = 4.734e-63 Identity = 106/227 (46.70%), Postives = 161/227 (70.93%), Query Frame = 0
Query: 713 ATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSL 939
A +N+ P F ++L WFL+D+PG CP AG AAY + + + DQ+GF YDV A+NFM FHTIL++S D+ EALR SR+L I+ +N+++ E ++ +F YS+FYV+YEQYLTMW D++++L S +++F VT + G ++ S+LI+++ I+MI N++G+MY WNI LN ++LVNLV+ IGIS+EFC+H V+ F + ++RS+ TLVN+GSS+
Sbjct: 1622 AGVDNRPTPFQFEKHLQWFLQDSPGDVCPPAGKAAYRDGVRLAELGA-DQEGFPHYDVSANNFMVFHTILRTSTDFSEALRWSRKLTDAIDETVNKDL-GEEERLNIFAYSVFYVYYEQYLTMWEDSLETLGYSLLAVFCVTLVLLGLDIASALIVILVILMILINMIGLMYWWNIQLNGVTLVNLVVTIGISVEFCAHMVRSFSVTNESDMIKRSKATLVNMGSSV 1846
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold22_size673200-snap-gene-4.23 (protein:Tk12689 transcript:maker-scaffold22_size673200-snap-gene-4.23-mRNA-1 annotation:"niemann-pick c1 protein isoform x3") HSP 1 Score: 451.44 bits (1160), Expect = 2.145e-140 Identity = 250/629 (39.75%), Postives = 370/629 (58.82%), Query Frame = 0
Query: 2 HTPFQIDFVFSGDKXASIPEEMSYYNTEIEPCN-IRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGF-LSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPE-STETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPP 627
+TP +I+F + E YN C+ NG CSCTDCE +C S + +HL + N + + L F + +GV I +++ R M +G KT + + + + L++++ F RWG CA + ++ L + L GIF++ V TDP+ LW++P SRSR EKDFF+ F PF+R+ Q+I+K K F Y +LF + + G +F + EF+L LRL KE++ + T + V L DICH PL P CNIQ++W+YWQDDP + ++G N T HNDTY+DHF++CS NP Q +T MKQ CMSKGG+P++P FVLGGF LS + + + ++ A+++T L+NN+ P + HLAM+WEKTF+EF++ ++ E + M+I F SERSI DE+ + + GDI + ISY M VYI +SLG S F ++ KITL++ G L V++++ +++G G++ P TLIIF+I+PFL+LA G DNIF+LV Q E ST+ +E I V V PS+L+++ + T F LG IS MPAVR+F++YA MAL +F +Q+T FI + D+ RQ DIF ++ P
Sbjct: 197 NTPIRINFYLESEPHH---EGGKLYNRSTIHCDEAPPNGDGACSCTDCERACQSPDFG-QVYHLSDEDSE-NYFDLWLLLGCLGIFFLSMGVFIGCLWMRH---RTKIYPMMASGDKKTKAAASCGT-----QTLNKFMFDQFYRWGLMCARHAAKIMALGFALVLVASGGIFFIEVETDPVRLWSAPTSRSRVEKDFFETAFEPFFRVEQIILKPKKNDPFMYRNLFEDDIQMGAVF-RPEFMLETLRLLKEVQALTTS-SGVSLSDICHKPLAPDQQECNIQSIWAYWQDDPDKFLESGINPTTGHNDTYIDHFLMCSNNPTLQQDQTFMKQGCMSKGGVPVQPVFVLGGFDLSKSNASQGSQQFSNPTALIVTILVNNH------PNDT---HLAMDWEKTFVEFMNAQLE--EGSDLMEITFNSERSIQDELERSSLGDIAVVLISYSTMLVYIMVSLGKIYSKSTFFVDIKITLSLIGTLGVLLAIASAIGTLGYLGLPTTLIIFQILPFLILAVGVDNIFILVNTVQSILEEDSTKDVKEIIALAVAKVGPSILMSTVAQVTAFLLGGISDMPAVRSFSIYAAMALAWNFVLQMTIFIGALYWDLYRQCALRADIFCCLQRSP 799 HSP 2 Score: 163.31 bits (412), Expect = 5.571e-41 Identity = 102/243 (41.98%), Postives = 145/243 (59.67%), Query Frame = 0
Query: 704 CQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFL-HKEGVNRVQRSEITLVNIGSSLPTSSAG 945
C C D + + G + R FL NP +CPKAG AAY +L++ +G V AS+F FH++L+ S D+ EALR SR+LA + + +N +Q RVFPYSIFYVFYEQYLTMW DT+ SL ++ +++F+V FTG ++ S++ I+VTI++ N+ G+M + I LNAISLVNLVM +G+ +EF SH V+ F + + + + RS LV G PT AG
Sbjct: 994 CTPCITKGDRPEPSLFGTLVPR-----FLAQNPDESCPKAGKAAYRHALHLSP-----GEG-ESVQVEASSFFAFHSVLRDSNDFTEALRWSRRLADNLTSMLNSG----DQHVRVFPYSIFYVFYEQYLTMWSDTLISLAVAVVAVFLVVLAFTGLDVFSAVAIMVTILVTLVNMGGVMVILGIDLNAISLVNLVMTVGVGVEFSSHLVQAFRSYTDEPSGLVRSRKALVEWG---PTILAG 1218
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold104_size368486-snap-gene-1.6 (protein:Tk07540 transcript:maker-scaffold104_size368486-snap-gene-1.6-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 91.6633 bits (226), Expect = 6.348e-19 Identity = 54/184 (29.35%), Postives = 104/184 (56.52%), Query Frame = 0
Query: 429 RSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTE-THQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIAR 611
RS D S D+N + + I+F+Y+ L LG C +++++ +++ G++ V +++ AS GI G + P + + IPFL++ G D++F+++Q ++ + T E G + ++ +TS T+ F +GA + +PA+++F L+ G+ +LI FF+Q T F++ M+LD R
Sbjct: 703 RSFSDIASGNIFTDVNMVVFGFAIVFIYVLLMLG-QFHC----VKNRVFVSLAGLVSVFMALVASYGICGTLGFPFS-PLHNFIPFLIMGLGIDDMFVIMQAWTKFAEHRKDLTKVEKFGETMKRAGVAITVTSITDFIAFGIGASTLLPALKSFCLFCGVGILITFFLQATWFVAWMSLDQDR 880
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold34_size539781-snap-gene-1.9 (protein:Tk05354 transcript:maker-scaffold34_size539781-snap-gene-1.9-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 88.1965 bits (217), Expect = 6.459e-18 Identity = 63/221 (28.51%), Postives = 113/221 (51.13%), Query Frame = 0
Query: 396 LAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTE-THQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQREN 615
+++++EK IE + + E + I RS D S+ D + Y +MF Y L LG K L+E + +A GG++ V + +G + G+ + P T I I+PFL L G D++F++VQ PE + T E IG + ++ +TS T+ F +GA++ +P ++AF + +A+ + +Q + F++L++LD R R++
Sbjct: 396 VSLDFEKEMIEVLLDGSKESEERSGVKIYANVARSFNDITSEAIFFDAVKMAAGYFLMFFYTMLFLG-----KLNLVEHRTWIAAGGIISVGMGLGIAFGVTSALGMPYT-PIHGILPFLALGIGIDDMFVIVQCWYNLSPEEQQRTLPEKIGLTMKHAGVAITVTSLTDVFAFGVGAVTILPGLQAFCVTCAIAIAAIYILQASWFVALLSLDQRRIRDH 610 HSP 2 Score: 63.5438 bits (153), Expect = 2.851e-10 Identity = 33/133 (24.81%), Postives = 79/133 (59.40%), Query Frame = 0
Query: 817 ARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSF 949
++ F +S Y +E + + ++L ++ + +FI+T + I L++L I + +++G ++ W ++++ IS +N+V+AIG+ +++ +H F+ +EG +R +R+ +LV++G ++ + G T+F
Sbjct: 843 SKAFSFSKVYAAWETDEVISFELWRNLALAMVCVFIITLVLLANVKIC-LMVLSCICLTLVDMVGFLHFWGLTIDTISCINIVLAIGLCVDYSAHIAHAFIVEEG-DREERAMNSLVSMGPAI--LNGGITTF 971
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold171_size289870-snap-gene-1.39 (protein:Tk00433 transcript:maker-scaffold171_size289870-snap-gene-1.39-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 87.0409 bits (214), Expect = 7.838e-18 Identity = 54/189 (28.57%), Postives = 104/189 (55.03%), Query Frame = 0
Query: 433 DEISKETT-GDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGI---FGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTE--THQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQREN 615
D+I+ ET GD + + + I+FVY+ + LG K +E++ L++ G+ + +++ + G+ FG P + +IPFL+L G D++F+++Q P + H+ IG + ++ +TS T+ F +G+ + +PA+R+F LY G+ ++ +F Q T F++ +ALD+ R +N
Sbjct: 312 DDIAAETIIGDAFMMPVGFTIVFVYVMIMLG-----KFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGP----MHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQN 491
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: snap_masked-scaffold472_size162276-processed-gene-0.4 (protein:Tk12251 transcript:snap_masked-scaffold472_size162276-processed-gene-0.4-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 85.8853 bits (211), Expect = 3.483e-17 Identity = 60/230 (26.09%), Postives = 116/230 (50.43%), Query Frame = 0
Query: 395 HLAMEWEKTFIEFIH--KWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGI---FGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALD---IARQRENF 616
+ +E+E ++ + K +P ++++A RS D K D+ + + I+F+Y+ LSLG K L+E + L+ G+ + ++V S G+ GF+ P + IIPFL+L G D++F++ Q P+ + T + + + ++ +TS T+ F +GA + +PA+R+F ++ + +L+ + +Q T F++ +A D IA R F
Sbjct: 331 EVTLEFESELLKALRAPKVHADPNIVVYLNVA----RSFNDLSEKVINTDVLLFGVGFGIVFIYVQLSLG-----KLNLVEQRPFLSAVGIGCIALTVFTSYGLCSLMGFVFSP----MHNIIPFLLLGIGIDDMFVICQSLDNLPPDPSLTVETRVALAMKHAGVAITVTSITDVAVFAIGASTVLPALRSFCVFCAVGILVVYILQATIFVAALAKDSQRIASHRNGF 547 HSP 2 Score: 66.2402 bits (160), Expect = 3.419e-11 Identity = 37/149 (24.83%), Postives = 83/149 (55.70%), Query Frame = 0
Query: 804 NAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSFCRF 952
N I V + N +R F + Y +E + +T+++L IS + +F+ T + G + ++L++++M N+ G M+ W ++++ +S VNLV+A+G+ +++ +H F+ G ++ +R+ + +IG ++ + G ++F F
Sbjct: 761 NKIKGIVKSMNFSSRAFAVANEYASWETDEIIAQETVRNLLISVVCVFVTTIVLIG-NFKACALVLLSVLMTLVNVGGFMHFWGLTIDVVSCVNLVIAVGLCVDYSAHIAHAFMTCSG-SKNERTIKAMRDIGPAV--LNGGFSTFLAF 905
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold193_size270907-snap-gene-0.15 (protein:Tk01088 transcript:maker-scaffold193_size270907-snap-gene-0.15-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 79.7221 bits (195), Expect = 2.532e-15 Identity = 68/268 (25.37%), Postives = 122/268 (45.52%), Query Frame = 0
Query: 353 FLSGNASDFTNPKYHQANAVVITFL--INNYNQYSRDPQEMRK--LHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRF-LIESKITLAIGGVLIVIISVGASVGI---FGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQ-EYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIAR 611
FLS D TN + A A V+ + +N +E + H +E+E ++ + P+ K + RS GD GD+ + I Y I+F ++ + LG RF +E + L+ G++ V + + + G+ G P + I+PFL+L G D++F++VQ E + G + ++ +TS T+ F +G + +PA+++F LYA + ++ +F Q T F++ MA+D R
Sbjct: 332 FLSEITYDPTNGQIIAARATVMRWFGRMNGTEALHNSVKERNEPITHGTLEFEGEMLKIMLNETGYPDGLKTYA---NARRSFGDVAGSTILGDVGKLGIGYTIVFFFVMIMLG------RFNCVEQRAFLSFAGIMGVGMGIITAYGVCSALGLFFGP----MHGILPFLLLGIGIDDMFVIVQCFNTLTEEEKSLPLIDKFGATMQHAGVAITITSITDVIAFGIGGSTVIPALKSFCLYASVGIIATYFYQCTFFVAWMAIDQRR 586 HSP 2 Score: 76.6406 bits (187), Expect = 2.865e-14 Identity = 51/212 (24.06%), Postives = 105/212 (49.53%), Query Frame = 0
Query: 741 PKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIGSSLPTSSAGSTSFCRF 952
P+ G Y + KK Q+ ++ S H + K++ A+ ++L +++ N R+FP S Y +E + + ++L ++ + +FI T +F +I+S ++LV +++ ++ G M+ WN++++ +S NL++AIG+ +++ +H F+ + G R QR TL NIG ++ + G ++F F
Sbjct: 759 PRGGK--YREQFEFKKPLQCGQEA---SQLMLSKINFVHKVFSGPKEHIPAMNRIKELIAQV-----------NASGRIFPMSQGYTLWETDEIISEELYRNLGLAVLCVFITT-LFLISNVITSFLVLVCVILSLIDVGGFMHFWNLTIDTVSANNLIIAIGLCVDYSAHIAHRFMVEHG-TRNQRVRQTLRNIGPAV--LNGGFSTFLAF 950
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold28_size608977-snap-gene-1.19 (protein:Tk05739 transcript:maker-scaffold28_size608977-snap-gene-1.19-mRNA-1 annotation:"AGAP010394-PA") HSP 1 Score: 77.0258 bits (188), Expect = 2.074e-14 Identity = 43/143 (30.07%), Postives = 81/143 (56.64%), Query Frame = 0
Query: 794 MSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEITLVNIG 936
M +Q+ E+ + NR T+E Q A P F+++ +QYL + TI+ + + I + IV+ + ++SSL I +I+ I ++G M W +SL+ ++L+NL+M IG S++F +H +++ ++G R +L +G
Sbjct: 664 MEQQMVMELRDICNRFSTDEMQIAVFQP---FFIYIDQYLDIKPQTIQCVVATAIIMIIVSLLLIP-SVVSSLWISFSIISIEVGVVGFMTWWGVSLDGVALINLIMCIGFSVDFSAHICYHYIAEDGKLPDDRIRGSLYGLG 802 HSP 2 Score: 67.3958 bits (163), Expect = 1.859e-11 Identity = 56/202 (27.72%), Postives = 95/202 (47.03%), Query Frame = 0
Query: 434 EISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVG-ASVGIFGFIDXPATLIIFEII------PFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRGPPT 628
E S+ + +I I + +I+F + + DN + SK + G+L S G A++ FGF A I E I PFL+L G D+ F+++ +R T E +GR D S+ +TS T+ F GA++ P+VR F L+ G+++ + T F +++AL +++N I I+ P+
Sbjct: 259 EKSRLSVTNILIINVIAMIIFSFGAALMSDN-------VRSKPVIGFSGLL----SAGMATIAAFGF----ACFIGVEFISLNMAAPFLLLGIGIDDTFVMLSSWRR--SSGHLTVPERMGRCYSDAAVSITVTSLTDFLSFMAGAVTPFPSVRIFCLFTGISVAFIYIWHCTFFGAILALSGYGEKKNLHSICCCIKATPS 443
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold627_size122700-snap-gene-0.37 (protein:Tk10659 transcript:maker-scaffold627_size122700-snap-gene-0.37-mRNA-1 annotation:"hypothetical protein AaeL_AAEL001299") HSP 1 Score: 71.2478 bits (173), Expect = 8.582e-13 Identity = 57/218 (26.15%), Postives = 102/218 (46.79%), Query Frame = 0
Query: 400 WEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDIN--TITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQREN 615
WEKTF++ I +H+ +A S ++ E+ + T I ++ I+ +++F IT + D + SK L + G++ I+ + G+ P I PFL+L G D+ F+ + +R P E + +G+ D S+ +TS T+ FF+G I+ P+V+ F LY G+A+ + I F + +AL + +N
Sbjct: 226 WEKTFLDTIETL-----EFEHIKVARFSSLTLEIELEENTNSVIPFFSVNIAIMVVFCVITCLMSD-------WVRSKPYLGLLGLVSAILGSITAFGVVMLCGVPFIGINLAA-PFLMLGIGIDDTFVFLSSWRRSNP--MEPIPKRLGQCYEDSAVSITITSLTDMLSFFVGIITPFPSVKIFCLYTGVAVAFTYMYHIFFFGACLALAGIAEEQN 428
BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold67_size430214-snap-gene-3.36 (protein:Tk00792 transcript:maker-scaffold67_size430214-snap-gene-3.36-mRNA-1 annotation:"patched 1 ") HSP 1 Score: 66.2402 bits (160), Expect = 4.149e-11 Identity = 57/221 (25.79%), Postives = 107/221 (48.42%), Query Frame = 0
Query: 399 EWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIE--SKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGR--IVGDVVP----SMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIAR 611
+W+ F + + + Q K I S + + K + + + I +M +Y T+++ R+ E S+ + + GVL+ +SV A +G+ G +D +I+PFL L G D +F+L + YG T +++ ++ R I+GDV+ S+LL S F A+ +PA+RAF+L A + + + + F ++++LD+ R
Sbjct: 321 DWQAKFSQEVARLTQEKHLNKKYAINAYSNSQLDHIMEKYSEFSVVNLAIGLGLMALYSTVTM------VRWSDEVFSQSGIGLCGVLLTALSVAAGLGLCGILDIAFNATTSQIVPFLALGLGVDAMFLL---SHTYG--ETVSNRRHLQRENIIGDVLRKAGISVLLMSLCNIAAFLAAALIPIPALRAFSLQAAILVGFNSVAMMILFPAVLSLDLRR 530 The following BLAST results are available for this feature:
BLAST of EMLSAG00000008403 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000008403 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
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BLAST of EMLSAG00000008403 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 10
BLAST of EMLSAG00000008403 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 25
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BLAST of EMLSAG00000008403 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 25
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BLAST of EMLSAG00000008403 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000008403 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 13
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s513:547002..563743+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000008403-691169 ID=EMLSAG00000008403-691169|Name=EMLSAG00000008403|organism=Lepeophtheirus salmonis|type=gene|length=16742bp|location=Sequence derived from alignment at LSalAtl2s513:547002..563743+ (Lepeophtheirus salmonis)back to top Add to Basket
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