BLAST of lysosomal aspartic protease vs. L. salmonis genes
Match: EMLSAG00000011388 (supercontig:LSalAtl2s:LSalAtl2s787:168898:171109:1 gene:EMLSAG00000011388 transcript:EMLSAT00000011388 description:"maker-LSalAtl2s787-augustus-gene-0.84")

HSP 1 Score: 538.11 bits (1385), Expect = 0.000e+0
Identity = 255/367 (69.48%), Postives = 304/367 (82.83%), Query Frame = 0

Query:   66 LVRIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVAK 432
            LVR+PV K +SAR+HF EVG+S+ ++R+RW+  G H EPLSNYLDAQYYGPITIG+PPQSF V+FDTGSSNLW+PS+ CH TNIACLLH+KYD   S TY  NG +FAIQYGSGSLSGFLS D VS+G +++ +Q F EA+SEPGMAFVAAKFDGILGMGY NIAV+ V P F NM  QG ++ PIFSFYLNRNP+A+VGGEII GGSDPDHY+G+ +Y+PVT++GYWQFKMD + V    FC  GCQ IADTGTSLIAGPS+EV  +N++LGGTPI+ GEYM +C+ I +LP I F +GG++F L G+DYVMQI   GKT+CLSGFMGLDVP PMGPIWILGDVFIGR+YT FDM  +RVGFA +K
Sbjct:   18 LVRVPVHKFQSARKHFYEVGSSIQLIRKRWNTVGAHPEPLSNYLDAQYYGPITIGSPPQSFKVIFDTGSSNLWIPSKSCHITNIACLLHHKYDHSKSSTYVANGTEFAIQYGSGSLSGFLSSDSVSMGEVEIGSQTFGEAMSEPGMAFVAAKFDGILGMGYSNIAVDGVVPPFYNMFKQGLIQEPIFSFYLNRNPDAKVGGEIIFGGSDPDHYKGNITYIPVTKKGYWQFKMDKMEVNSKSFCQNGCQAIADTGTSLIAGPSIEVNALNQLLGGTPIINGEYMFNCEDIPNLPPITFTIGGEEFVLSGEDYVMQITQFGKTVCLSGFMGLDVPEPMGPIWILGDVFIGRYYTVFDMGKDRVGFAQSK 384          

BLAST of lysosomal aspartic protease vs. L. salmonis genes
Match: EMLSAG00000000355 (supercontig:LSalAtl2s:LSalAtl2s1052:77306:79567:1 gene:EMLSAG00000000355 transcript:EMLSAT00000000355 description:"maker-LSalAtl2s1052-augustus-gene-0.4")

HSP 1 Score: 358.992 bits (920), Expect = 6.748e-122
Identity = 183/395 (46.33%), Postives = 249/395 (63.04%), Query Frame = 0

Query:   45 MRGLSVLLALAVLMGCGMADHLVRIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKF-CSG-----GCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGE--YMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            M+ L   L L+ L+    A  +  + + KI + ++   +V  S  ++ +RW+      + LSN++DAQYYG ITIGTPPQ F VVFDTGSSNLW+PS +C   NIAC LH KY++  S TY ++G++F IQYGSG ++G  S D   +  +    Q F E L +PG+ F+AAKFDGILGMG+  I++  V PVF +MV Q  V+  +FSF+LNR+ + E GG + LGG+D   YEGD +Y+ +  E YW+ KMD + +G     C+G     GC  I DTG SL  GP  EV  INK +G  PI+ G    M+DC+K+  LP IDF L G  F+L   +Y+ ++   G + C+SGFMG+D+  PMGP WILGD FIG +Y+ FDM N RVG A A
Sbjct:    1 MKFLISFLLLSGLVALSYA-KISSVTLNKI-NKQKTLDDVIESGRIISQRWNMRD-ESQDLSNFMDAQYYGEITIGTPPQKFNVVFDTGSSNLWIPSSKCSLLNIACQLHKKYNAKKSSTYSEDGREFFIQYGSGQVAGHFSSDTACIADVCPTEQAFGEVLKQPGIQFIAAKFDGILGMGFKRISLEGVPPVFQSMVDQKLVDDAVFSFWLNRDVDEEFGGRLTLGGTDSSLYEGDITYIDLVGEDYWRIKMDSMKMGNESIGCAGTEENPGCMAIVDTGCSLSVGPKKEVEAINKKIGAKPILPGSPXAMVDCEKLSELPNIDFTLNGHVFSLTPNEYIWKVTQQGVSQCISGFMGMDL--PMGPWWILGDNFIGTYYSVFDMGNARVGLAKA 390          

BLAST of lysosomal aspartic protease vs. L. salmonis genes
Match: EMLSAG00000002032 (supercontig:LSalAtl2s:LSalAtl2s136:1235703:1237501:-1 gene:EMLSAG00000002032 transcript:EMLSAT00000002032 description:"maker-LSalAtl2s136-snap-gene-12.8")

HSP 1 Score: 163.696 bits (413), Expect = 4.372e-47
Identity = 110/355 (30.99%), Postives = 171/355 (48.17%), Query Frame = 0

Query:   85 GTSLDVVRRRWSK--NGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVG-GEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSG-----GCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            G S+ V   R SK  N  +++ L N    +++  I+IGTPPQ F  V D  S+N WVPS +C   NI C                                     +  VG   V+ QVF EA SE  + F  A +DG LGMG+   +        NN++ +  ++  +FS +L+R   ++   G++ILGG D  +Y G+ SY+P+  +  W+ KM+ + + G     G     GC VI D GT+ +A P+                 G Y + C  I SLP I+F+   + F L+ +DY+++ + +G  +CLSGF+GL       P W LG  F+  FY+ +D++N ++G A +
Sbjct:   19 GVSIKVPLSRGSKIDNEFNMDRL-NIDKLEFFSEISIGTPPQLFNTVLDMESTNSWVPSSKCGSFNIPCTCTR---------------------------------VRIVGTKCVEQQVFGEATSESLVPFGEAIYDGALGMGFSKDS----NSFLNNLIDRNLIDEHLFSIWLSRESVSKNNNGQLILGGIDSSYYSGNISYIPLNSDSMWRTKMNSIKIKGIHRGCGYAGSPGCNVIFDAGTTQMA-PTY----------------GYYKVYCNAILSLPTIEFVFDDQIFKLKPQDYIIETRILGMKVCLSGFVGL--AKEKKPQWYLGSNFLSAFYSVYDVENKKIGLATS 316          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|205831550|sp|Q03168.2|ASPP_AEDAE (RecName: Full=Lysosomal aspartic protease; Flags: Precursor)

HSP 1 Score: 527.709 bits (1358), Expect = 0.000e+0
Identity = 248/388 (63.92%), Postives = 307/388 (79.12%), Query Frame = 0

Query:   45 MRGLSVLLALAVLMGCGMADHLVRIPVTKIKSARRHFQEVGTSLDVVRRRWSK-NGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            ++ +  L+ LAVL     AD  VR+ + K +SAR+HF+ V T +  +R +++  +GP  EPLSNYLDAQYYG ITIGTPPQSF VVFDTGSSNLWVPS++C +TNIACL+HNKY++  S T++KNG  F IQYGSGSLSG+LS D V +GG+ V  Q FAEA++EPG+ FVAAKFDGILG+GY +I+V+ V PVF NM  QG +++P+FSFYLNR+P A  GGEII GGSD + Y GDF+Y+ V R+ YWQFKMD + VG T+FC+ GC+ IADTGTSLIAGP  EVT INK +GGTPI+ GEYM+DC  I  LPKI F+LGGK F LEG DYV+++  MGKTICLSGFMG+D+PPP GP+WILGDVFIG++YTEFDM N+RVGFA A
Sbjct:    3 IKSIIALVCLAVL---AQAD-FVRVQLHKTESARQHFRNVDTEIKQLRLKYNAVSGPVPEPLSNYLDAQYYGAITIGTPPQSFKVVFDTGSSNLWVPSKECSFTNIACLMHNKYNAKKSSTFEKNGTAFHIQYGSGSLSGYLSTDTVGLGGVSVTKQTFAEAINEPGLVFVAAKFDGILGLGYSSISVDGVVPVFYNMFNQGLIDAPVFSFYLNRDPSAAEGGEIIFGGSDSNKYTGDFTYLSVDRKAYWQFKMDSVKVGDTEFCNNGCEAIADTGTSLIAGPVSEVTAINKAIGGTPIMNGEYMVDCSLIPKLPKISFVLGGKSFDLEGADYVLRVAQMGKTICLSGFMGIDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVGFATA 386          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|146286061|sp|O93428.2|CATD_CHIHA (RecName: Full=Cathepsin D; Flags: Precursor)

HSP 1 Score: 462.611 bits (1189), Expect = 3.649e-161
Identity = 219/394 (55.58%), Postives = 282/394 (71.57%), Query Frame = 0

Query:   51 LLALAVLMGCGMA-DHLVRIPVTKIKSARRHFQEVGT----------SLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGT-KFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVAK 432
            +L L V     +  D LVRIP+ K +S RR   + G           SL       + N P  E L NYLDAQYYG I +GTPPQ F VVFDTGSSNLWVPS  C   +IACLLH+KY+SG S TY KNG  FAIQYGSGSLSG+LSQD  ++G + + +Q+F EA+ +PG+AF+AAKFDGILGM YP I+V+ V PVF+N+++Q  VE  +FSFYLNRNP+ E GGE++LGG+DP +Y GDF+YV VTR+ YWQ ++D ++VG     C+GGC+ I D+GTSLI GPSVEV  + K +G  P++ GEYM++C  + SLP I F +GG+ +TL G+ Y++++   GKT+CLSGFMGLD+P P GP+WILGDVF+G++YT FD   NRVGFA AK
Sbjct:    3 MLLLCVFSALALTNDALVRIPLKKFRSIRRQLTDSGKRAEELLADHHSLKYNLSFPASNAPTPETLKNYLDAQYYGEIGLGTPPQPFTVVFDTGSSNLWVPSIHCSLLDIACLLHHKYNSGKSSTYVKNGTAFAIQYGSGSLSGYLSQDTCTIGDLAIDSQLFGEAIKQPGVAFIAAKFDGILGMAYPRISVDGVAPVFDNIMSQKKVEQNVFSFYLNRNPDTEPGGELLLGGTDPKYYTGDFNYVNVTRQAYWQIRVDSMAVGDQLSLCTGGCEAIVDSGTSLITGPSVEVKALQKAIGAFPLIQGEYMVNCDTVPSLPVISFTVGGQVYTLTGEQYILKVTQAGKTMCLSGFMGLDIPAPAGPLWILGDVFMGQYYTVFDRDANRVGFAKAK 396          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|25452827|sp|Q9DEX3.1|CATD_CLUHA (RecName: Full=Cathepsin D; Flags: Precursor)

HSP 1 Score: 459.914 bits (1182), Expect = 4.348e-160
Identity = 217/378 (57.41%), Postives = 276/378 (73.02%), Query Frame = 0

Query:   63 ADHLVRIPVTKIKSARRHFQEVG----------TSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGT-KFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFA 429
            +D +VRIP+ K +S RR   + G           SL   +   S N P  E L NY+DAQYYG I +GTP Q F VVFDTGSSNLW+PS  C +T+IACLLH+KY+   S TY KNG +FAIQYGSGSLSG+LSQD  ++G I V+ Q+F EA+ +PG+AF+AAKFDGILGM YP I+V+ V PVF+ M++Q  VE  +FSFYLNRNP+ E GGE++LGG+DP +Y GDF+YVPVTR+ YWQ  MDG+S+G     C  GC+ I DTGTSLI GP  EV  + K +G  P++ GEYM+DCKK+ +LP I F +GGK ++L G+ YV++    GKTICLSG MGL++PPP GP+WILGDVFIG++YT FD ++NRVGFA
Sbjct:   16 SDAIVRIPLKKFRSIRRTLSDSGLNVEQLLAGTNSLQHNQGFPSSNAPTPETLKNYMDAQYYGEIGLGTPVQMFTVVFDTGSSNLWLPSIHCSFTDIACLLHHKYNGAKSSTYVKNGTEFAIQYGSGSLSGYLSQDSCTIGDIVVEKQLFGEAIKQPGVAFIAAKFDGILGMAYPRISVDGVPPVFDMMMSQKKVEQNVFSFYLNRNPDTEPGGELLLGGTDPKYYTGDFNYVPVTRQAYWQIHMDGMSIGSQLTLCKDGCEAIVDTGTSLITGPPAEVRALQKAIGAIPLIQGEYMIDCKKVPTLPTISFNVGGKTYSLTGEQYVLKESQGGKTICLSGLMGLEIPPPAGPLWILGDVFIGQYYTVFDRESNRVGFA 393          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|461696|sp|Q05744.1|CATD_CHICK (RecName: Full=Cathepsin D; Contains: RecName: Full=Cathepsin D light chain; Contains: RecName: Full=Cathepsin D heavy chain; Flags: Precursor)

HSP 1 Score: 451.055 bits (1159), Expect = 1.567e-156
Identity = 214/375 (57.07%), Postives = 272/375 (72.53%), Query Frame = 0

Query:   66 LVRIPVTKIKSARRHFQEVGTSLD----VVRRRWSKNG------PHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVG-GTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFA 429
            L+RIP+TK  S RR   EVG+ +     + +    K G      P  E L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  CH  +IACLLH+KYD+  S TY +NG +FAI YG+GSLSGFLSQD V++G + +KNQ+F EA+ +PG+ F+AAKFDGILGM +P I+V+KVTP F+N++ Q  +E  IFSFYLNR+P A+ GGE++LGG+DP +Y GDFS+V VTR+ YWQ  MD + V  G   C GGC+ I DTGTSLI GP+ EV ++   +G  P++ G+Y++ C KI SLP +  +LGGK + L G+ YV ++ A G+TICLSGF GLDVPPP GP+WILGDVFIG +YT FD  N+ VGFA
Sbjct:   21 LIRIPLTKFTSTRRMLTEVGSEIPDMNAITQFLKFKLGFADLAEPTPEILKNYMDAQYYGEIGIGTPPQKFTVVFDTGSSNLWVPSVHCHLLDIACLLHHKYDASKSSTYVENGTEFAIHYGTGSLSGFLSQDTVTLGNLKIKNQIFGEAVKQPGITFIAAKFDGILGMAFPRISVDKVTPFFDNVMQQKLIEKNIFSFYLNRDPTAQPGGELLLGGTDPKYYSGDFSWVNVTRKAYWQVHMDSVDVANGLTLCKGGCEAIVDTGTSLITGPTKEVKELQTAIGAKPLIKGQYVISCDKISSLPVVTLMLGGKPYQLTGEQYVFKVSAQGETICLSGFSGLDVPPPGGPLWILGDVFIGPYYTVFDRDNDSVGFA 395          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|115720|sp|P24268.1|CATD_RAT (RecName: Full=Cathepsin D; Contains: RecName: Full=Cathepsin D 12 kDa light chain; Contains: RecName: Full=Cathepsin D 9 kDa light chain; Contains: RecName: Full=Cathepsin D 34 kDa heavy chain; Contains: RecName: Full=Cathepsin D 30 kDa heavy chain; Flags: Precursor)

HSP 1 Score: 436.417 bits (1121), Expect = 1.316e-150
Identity = 217/384 (56.51%), Postives = 270/384 (70.31%), Query Frame = 0

Query:   66 LVRIPVTKIKSARRHFQEVGTSL-DVVRR----RWSKNG------PHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSV------GGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGT-KFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            L+RIP+ K  S RR   EVG S+ D++ +    ++S         P  E L NYLDAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+S  S TY KNG  F I YGSGSLSG+LSQD VSV      GGI V+ Q+F EA  +PG+ F+AAKFDGILGMGYP I+VNKV PVF+N++ Q  VE  IFSFYLNR+P  + GGE++LGG+D  +Y G+ SY+ VTR+ YWQ  MD L VG     C GGC+ I DTGTSL+ GP  EV ++ K +G  P++ GEYM+ C+K+ SLP I F LGG+ + L  + Y++++   GKTICLSGFMG+D+PPP GP+WILGDVFIG +YT FD + NRVGFA A
Sbjct:   21 LIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|115718|sp|P18242.1|CATD_MOUSE (RecName: Full=Cathepsin D; Flags: Precursor)

HSP 1 Score: 433.721 bits (1114), Expect = 1.334e-149
Identity = 213/387 (55.04%), Postives = 266/387 (68.73%), Query Frame = 0

Query:   66 LVRIPVTKIKSARRHFQEVGTSLD-------VVRRRWSKNGPHVEPLS----NYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSV---------GGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGT-KFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            ++RIP+ K  S RR   EVG S++       + +     +    EP+S    NYLDAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+S  S TY KNG  F I YGSGSLSG+LSQD VSV          GI V+ Q+F EA  +PG+ FVAAKFDGILGMGYP+I+VN V PVF+N++ Q  V+  IFSFYLNR+PE + GGE++LGG+D  +Y G+ SY+ VTR+ YWQ  MD L VG     C GGC+ I DTGTSL+ GP  EV ++ K +G  P++ GEYM+ C+K+ SLP +   LGGK + L    Y++++   GKTICLSGFMG+D+PPP GP+WILGDVFIG +YT FD  NNRVGFA A
Sbjct:   21 IIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSGPLWILGDVFIGSYYTVFDRDNNRVGFANA 407          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|115717|sp|P07339.1|CATD_HUMAN (RecName: Full=Cathepsin D; Contains: RecName: Full=Cathepsin D light chain; Contains: RecName: Full=Cathepsin D heavy chain; Flags: Precursor)

HSP 1 Score: 432.565 bits (1111), Expect = 5.115e-149
Identity = 212/388 (54.64%), Postives = 270/388 (69.59%), Query Frame = 0

Query:   67 VRIPVTKIKSARRHFQEVGTSL-DVVRR----RWSK------NGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSV-----------GGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVG-GTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            VRIP+ K  S RR   EVG S+ D++ +    ++S+       GP  E L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+S  S TY KNG  F I YGSGSLSG+LSQD VSV           GG+ V+ QVF EA  +PG+ F+AAKFDGILGM YP I+VN V PVF+N++ Q  V+  IFSFYL+R+P+A+ GGE++LGG+D  +Y+G  SY+ VTR+ YWQ  +D + V  G   C  GC+ I DTGTSL+ GP  EV ++ K +G  P++ GEYM+ C+K+ +LP I   LGGK + L  +DY +++   GKT+CLSGFMG+D+PPP GP+WILGDVFIGR+YT FD  NNRVGFA A
Sbjct:   22 VRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEA 409          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|85540968|sp|Q4LAL9.1|CATD_CANFA (RecName: Full=Cathepsin D; Flags: Precursor)

HSP 1 Score: 426.402 bits (1095), Expect = 1.150e-146
Identity = 210/386 (54.40%), Postives = 266/386 (68.91%), Query Frame = 0

Query:   67 VRIPVTKIKSARRHFQEVGTSL-DVVRR----RWSKNGPHV------EPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSV---------GGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGT-KFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            VRIP+ K  S RR   E+G  + D++ +    ++++  P V      E L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+SG S TY KNG  F I YGSGSLSG+LSQD VSV          GI V+ Q F EA  +PG+ F+AAKFDGILGM YP I+VN V PVF+N++ Q  VE  IFSFYLNR+P A+ GGE++LGG+D  +Y+G  SY+ VTR+ YWQ  M+ + VG +   C GGC+ I DTGTSLI GP  EV ++ K +G  P++ GEYM+ C+K+ +LP +   LGGK + L  +DY +++   GKTICLSGFMG+D+PPP GP+WILGDVFIG +YT FD   NRVG A A
Sbjct:   22 VRIPLHKFTSVRRTMTELGGPVEDLIAKGPISKYAQGAPAVTGGPIPEMLRNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSGKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSALSGLAGIKVERQTFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVEKNIFSFYLNRDPNAQPGGELMLGGTDSKYYKGPLSYLNVTRKAYWQVHMEQVDVGSSLTLCKGGCEAIVDTGTSLIVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPDVTLKLGGKLYKLSSEDYTLKVSQGGKTICLSGFMGMDIPPPGGPLWILGDVFIGCYYTVFDRDQNRVGLAQA 407          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|13637914|sp|P80209.2|CATD_BOVIN (RecName: Full=Cathepsin D; Flags: Precursor)

HSP 1 Score: 416.387 bits (1069), Expect = 5.264e-143
Identity = 201/387 (51.94%), Postives = 257/387 (66.41%), Query Frame = 0

Query:   66 LVRIPVTKIKSARRHFQEVGTSLDVVRRRWS-----------KNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSV---------GGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGT-KFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            ++RIP+ K  S RR   E    +  +  +             + GP  E L NY+DAQYYG I IGTPPQ F VVFDTGS+NLWVPS  C   +IAC  H KY+S  S TY KNG  F I YGSGSLSG+LSQD VSV         GG+ V+ Q F EA+ +PG+ F+AAKFDGILGM YP I+VN V PVF+N++ Q  V+  +FSF+LNR+P+A+ GGE++LGG+D  +Y G   +  VTR+ YWQ  MD L VG +   C GGC+ I DTGTSLI GP  EV ++ K +G  P++ GEYM+ C+K+ SLP++   LGGK + L  +DY +++     T+CLSGFMG+D+PPP GP+WILGDVFIGR+YT FD   NRVG A A
Sbjct:    1 VIRIPLHKFTSIRRTMSEAAGXVXXLIAKGPISKYATGEPAVRQGPIPELLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWTHRKYNSDKSSTYVKNGTTFDIHYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDKNVFSFFLNRDPKAQPGGELMLGGTDSKYYRGSLMFHNVTRQAYWQIHMDQLDVGSSLTVCKGGCEAIVDTGTSLIVGPVEEVRELQKAIGAVPLIQGEYMIPCEKVSSLPEVTVKLGGKDYALSPEDYALKVSQAETTVCLSGFMGMDIPPPGGPLWILGDVFIGRYYTVFDRDQNRVGLAEA 387          

BLAST of lysosomal aspartic protease vs. SwissProt
Match: gi|18203300|sp|Q9MZS8.1|CATD_SHEEP (RecName: Full=Cathepsin D; Flags: Precursor)

HSP 1 Score: 395.586 bits (1015), Expect = 3.096e-135
Identity = 185/334 (55.39%), Postives = 239/334 (71.56%), Query Frame = 0

Query:   91 VRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSV---------GGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGT-KFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGR 414
             R    + GP  E L+NY+DAQYYG I IGTPPQ F VVFDTGS+NLWVPS  C   +IAC +H+KY+S  S TY KNG  F I YGSGSLSG+LSQD VSV         GG+ V+ Q F EA+ +PG+ F+AAKFDGILGM YP I+VN V PVF+N++ Q  V+  +FSF+LNR+P+A+ G E++LGG+D  +Y G  +Y  VTR+ YWQ  MD L VG +   C GGC+ I DTGTSL+ GP  EV +++K +G  P++ GEYM+ C+K+ SLP++   LGGK +TL  +DY +++   G T+CLSGFMG+D+PPP GP+WILGDVFIGR
Sbjct:   32 TREPAVRQGPIPELLTNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTTFDIHYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVFIAAKFDGILGMAYPRISVNNVLPVFDNLMRQKLVDKNVFSFFLNRDPKAQPGEELMLGGTDSKYYRGSLTYHNVTRQAYWQIHMDQLDVGSSLTVCKGGCEAIVDTGTSLMVGPVDEVRELHKAIGAVPLIQGEYMIPCEKVSSLPQVTLKLGGKDYTLSPEDYTLKVSQAGTTVCLSGFMGMDIPPPGGPLWILGDVFIGR 365          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|868477657|gb|AKO90276.1| (cathepsin D [Tigriopus japonicus])

HSP 1 Score: 693.73 bits (1789), Expect = 0.000e+0
Identity = 332/389 (85.35%), Postives = 357/389 (91.77%), Query Frame = 0

Query:   45 MRGLSVLLALAVLMGCGMADH-LVRIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVAK 432
            MRG+ V L LA L+GC + +  LVRIPVTKI+SARRHFQ VGTSLD+VR+RW+K GPH EPLSNYLDAQYYGPITIG PPQSFMVVFDTGSSNLWVPSR+CHYTNIACLLHNKY++ ASKTYKKNG+KFAIQYGSGSLSGFLSQD V+VGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMV QG V+ PIFSFYLNR+P AEVGGEII GGSDPDHYE  F+YVPVTR+GYWQFKMD ++VGGT FC  GCQ IADTGTSLIAGPS EVTKINKMLGGTP++GGEYM+DCKKIDSLP IDF +GGKKFTL GKDYVMQIK+MGK ICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKN+RVGFA AK
Sbjct:    1 MRGIFVFLTLA-LLGCALGEKPLVRIPVTKIQSARRHFQAVGTSLDIVRKRWNKKGPHPEPLSNYLDAQYYGPITIGNPPQSFMVVFDTGSSNLWVPSRKCHYTNIACLLHNKYNAEASKTYKKNGQKFAIQYGSGSLSGFLSQDTVNVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVQQGQVDEPIFSFYLNRDPNAEVGGEIIFGGSDPDHYEAPFAYVPVTRKGYWQFKMDSVNVGGTAFCKKGCQAIADTGTSLIAGPSDEVTKINKMLGGTPVMGGEYMIDCKKIDSLPNIDFTIGGKKFTLTGKDYVMQIKSMGKLICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNDRVGFANAK 388          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|91093044|ref|XP_966517.1| (PREDICTED: lysosomal aspartic protease [Tribolium castaneum] >gi|270002651|gb|EEZ99098.1| Lysosomal aspartic protease-like Protein [Tribolium castaneum])

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 271/388 (69.85%), Postives = 314/388 (80.93%), Query Frame = 0

Query:   45 MRGLSVLLALAVLMGCGMADHLVRIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGG-TKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            +R   +   + VL+    A+  VR+P+ K+KSARR  QEVGT +  VR R+   GP  EPLSNYLDAQYYGPI+IG PPQ+F VVFDTGSSNLWVPS++CHYTNIACLLHNKYDS  SKTYKKNG  FAIQYGSGSLSGFLS D+V+VGG+ V+ Q FAEA+SEPG+AFVAAKFDGILGM Y  I+V+ VTPVF NM+ Q  V  P+FSFYLNR+P A  GGEIILGGSDP HY+GDF+Y+ V R+ YWQFKMD +SVGG   FC+ GC+ IADTGTSLIAGP  EV  INK +G TPIVGGEYM+DC  I +LP IDF LGGK FTLEGKDYV+++  MGKTICLSGFMG+D+PPP GP+WILGDVFIG+FYTEFD+ NNRVGFAVA
Sbjct:    2 LRSSVIFFIVCVLV----ANAFVRVPLYKVKSARRSLQEVGTHVQQVRMRYG--GPTPEPLSNYLDAQYYGPISIGNPPQNFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSSQSKTYKKNGTDFAIQYGSGSLSGFLSTDIVTVGGLKVQQQTFAEAMSEPGLAFVAAKFDGILGMAYNRISVDGVTPVFYNMIQQNLVAQPVFSFYLNRDPSAAQGGEIILGGSDPAHYKGDFTYLSVDRQAYWQFKMDSISVGGKNTFCANGCEAIADTGTSLIAGPVSEVQGINKAIGATPIVGGEYMVDCNLIPNLPLIDFTLGGKNFTLEGKDYVLRVAQMGKTICLSGFMGIDIPPPNGPLWILGDVFIGKFYTEFDLGNNRVGFAVA 383          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|260810438|ref|XP_002599971.1| (hypothetical protein BRAFLDRAFT_74093 [Branchiostoma floridae] >gi|229285255|gb|EEN55983.1| hypothetical protein BRAFLDRAFT_74093 [Branchiostoma floridae])

HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0
Identity = 267/393 (67.94%), Postives = 317/393 (80.66%), Query Frame = 0

Query:   45 MRGLSVLLALAVLMGCGMADHLVRIPVTKIKSARRHFQEVGTSLDVVRRRWS-----KNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVAK 432
            M+ L VLLA+        A+ L RIP+TK+K+ RRH  EVG   D + + +S       GP  EPLSNYLDAQY+GPI+IGTPPQSF VVFDTGSSNLWVPS++CHY+NIACLLHNKYD+  S TYKKNG+KFAIQYGSGSLSGFLSQD VSV GI+VK+Q FAEALSEPGMAFVAAKFDGILGMGY NIAV+ V P F NMV+QG V  P+FSFYLNR+P A  GGE+ILGG+DP++Y GDF+++ VTR+GYWQFKMDG++VGG+ FC  GCQ IADTGTSLIAGP  EV K++K +G TP+ GGEY +DC K+ SLP I FILGGK+F L GK+Y++Q+K  G TICLSGFMG+D+PPP GP+WILGDVFIG +YT+FD+  N VGFA AK
Sbjct:    1 MKFLLVLLAIVA-----TANALHRIPLTKMKTVRRHLAEVGVPYDKIIKDYSGKYYNMTGPQPEPLSNYLDAQYFGPISIGTPPQSFQVVFDTGSSNLWVPSKKCHYSNIACLLHNKYDASKSSTYKKNGEKFAIQYGSGSLSGFLSQDTVSVAGIEVKDQTFAEALSEPGMAFVAAKFDGILGMGYSNIAVDGVVPPFYNMVSQGAVPEPVFSFYLNRDPSATAGGELILGGADPNYYTGDFTFLDVTRKGYWQFKMDGINVGGSTFCQEGCQAIADTGTSLIAGPIEEVNKLHKQIGATPLAGGEYKVDCSKVTSLPTISFILGGKEFELTGKEYILQVKQFGMTICLSGFMGMDIPPPAGPLWILGDVFIGSYYTQFDLGKNLVGFATAK 388          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|1059399934|ref|XP_017772898.1| (PREDICTED: lysosomal aspartic protease [Nicrophorus vespilloides])

HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0
Identity = 267/388 (68.81%), Postives = 314/388 (80.93%), Query Frame = 0

Query:   45 MRGLS-VLLALAVLMGCGMADHLVRIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            MR LS +   LA +     A   VR+P+ K KS+RR  QEVGT +  V+ R+   GP  EPLSNY+DAQYYGPI+IG PPQ F VVFDTGSSNLWVPS++CH+TNIACLLHNKYDS ASKTYK NG  FAI YGSGSLSGFLS D+V++GG+DVK+Q FAEA+SEPG+AFVAAKFDGILGMGY NIAV+ V PVF+NM+AQG +  PIFSFYLNR+P+A  GGEII GGSDP HY+G+F+Y+ V R+ YWQFKMD + +G   FC+ GC+ IADTGTSLIAGP  E+T INK +GGTPIVGGEYM+DC  I  LP IDF++ GK FTLE KDYV+++  MGKTICLSGFMG+D+PPP GP+WILGDVFIG+FYTEFDM NNRVGFA A
Sbjct:    1 MRLLSSIFFLLATIYAVSSA--FVRVPLIKDKSSRRTLQEVGTHVQQVQFRY--GGPQPEPLSNYMDAQYYGPISIGNPPQKFKVVFDTGSSNLWVPSKKCHFTNIACLLHNKYDSMASKTYKANGTDFAIHYGSGSLSGFLSTDIVNLGGMDVKDQTFAEAMSEPGLAFVAAKFDGILGMGYSNIAVDGVPPVFDNMLAQGLISDPIFSFYLNRDPQAADGGEIIFGGSDPAHYKGEFTYLDVDRKAYWQFKMDKVKIGDKTFCAKGCEAIADTGTSLIAGPLDEITAINKAIGGTPIVGGEYMIDCTLIPKLPTIDFVMAGKTFTLEAKDYVLRVAQMGKTICLSGFMGIDIPPPNGPLWILGDVFIGKFYTEFDMGNNRVGFAEA 384          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|146217392|gb|ABQ10738.1| (cathepsin D [Penaeus monodon])

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 265/372 (71.24%), Postives = 301/372 (80.91%), Query Frame = 0

Query:   63 ADHLVRIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTK--FCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVAK 432
            AD L RI + K KSARR  QEV T++ VV R+W   GP  EPLSNY+DAQYYGPITIGTPPQSF VVFDTGSSNLWVPS+QCH+TNIACL+HNKYD+  S TYKKNG KF IQYGSGSLSG+LS D VSVG + VK+Q FAEA+SEPG+AFVAAKFDGILGM Y  IAV+ VTPVF NMV Q  V +PIFSFYLNR+P A  GGE+ILGGSDP +Y GDF+YVPV R+GYWQFKMDGL + GT   FC GGC+ IADTGTSLIA PS E   INK +G  PI+GGE+ +DC  I  LP I F+L GK FTLEGKDY++++   G+T CLSGF+GLDVPPPMGPIWILGD+FIGRFYTEFDM NNRVGFA +K
Sbjct:   15 ADELPRIKLHKFKSARRSLQEVDTAVKVVHRKWGNKGPMPEPLSNYMDAQYYGPITIGTPPQSFRVVFDTGSSNLWVPSKQCHFTNIACLIHNKYDATKSSTYKKNGTKFDIQYGSGSLSGYLSTDTVSVGSVSVKDQTFAEAMSEPGLAFVAAKFDGILGMAYDRIAVDGVTPVFYNMVNQNVVPAPIFSFYLNRDPAAAEGGELILGGSDPAYYTGDFTYVPVDRQGYWQFKMDGLQMNGTTVPFCDGGCEAIADTGTSLIAAPSEEARLINKKIGAKPIMGGEWSVDCNLIPHLPTISFVLAGKPFTLEGKDYILRVSQFGQTTCLSGFIGLDVPPPMGPIWILGDIFIGRFYTEFDMGNNRVGFAESK 386          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|1008424892|gb|AMQ98967.1| (cathepsin-D [Macrobrachium rosenbergii])

HSP 1 Score: 559.296 bits (1440), Expect = 0.000e+0
Identity = 262/366 (71.58%), Postives = 303/366 (82.79%), Query Frame = 0

Query:   68 RIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTK--FCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            RIP+ K KSAR+  +EV TS+ + RRRW   GP  EPLSNY+DAQYYGPI+IGTPPQSF VVFDTGSSNLWVPS+QCH+TNIACL+HNKYDS  S TYKKNG +FAIQYGSGSLSG+LS D VSVG + VK+Q FAEALSEPGMAFVAAKFDGILGM Y  IAV+ VTPVF NMV+Q  V +P+FSFYLNR+P A  GGE+ILGGSDP +Y+GDF+Y+PV R+GYWQFKMDG+ + G     C+GGC+ IADTGTSLIA PS E   INK +G  PIVGGE+M+DC  I +LP I F+L GK FTLEGKDY++++   GKT CLSGF+GLDVPPPMGP+WILGDVFIGRFYTEFDM+NNRVGFA A
Sbjct:   19 RIPLRKFKSARQSLREVDTSIKLTRRRWGNGGPMPEPLSNYMDAQYYGPISIGTPPQSFRVVFDTGSSNLWVPSKQCHFTNIACLIHNKYDSRKSSTYKKNGTEFAIQYGSGSLSGYLSTDTVSVGSVVVKDQTFAEALSEPGMAFVAAKFDGILGMAYDRIAVDGVTPVFYNMVSQKLVPAPVFSFYLNRDPSAPEGGELILGGSDPKYYKGDFTYLPVDRQGYWQFKMDGVQIDGADVPVCTGGCEAIADTGTSLIAAPSEEARLINKKIGAKPIVGGEWMVDCDLIPNLPTISFVLNGKPFTLEGKDYILRVSQFGKTTCLSGFIGLDVPPPMGPMWILGDVFIGRFYTEFDMENNRVGFATA 384          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|1276315184|gb|ATU82734.1| (secreted A1 protease-like protein [Pristhesancus plagipennis])

HSP 1 Score: 557.755 bits (1436), Expect = 0.000e+0
Identity = 261/390 (66.92%), Postives = 320/390 (82.05%), Query Frame = 0

Query:   50 VLLALAVLMG--CGM---ADHLVRIPVTKIKSARRHFQEVGTSLDVVRRRWSKN--GPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVAK 432
            V+L  A+L+   CG+   + +LVR+P+TKI+SARR FQEVGT+++ +  +++ N  GP  EPLSNYLDAQYYGPIT+G PPQSF VVFDTGSSNLWVPS++C   NIAC +H KYDS  SKTY  NG+KFAI YGSGSLSG+LS+D +S+GGI + NQ FAEA++EPGM FVAAKFDGILG+GY  I+V+KVTP F NM  QG V++P+FSFYL+R+  A VGGEII GGSDPD Y GDF+Y+PV R+GYWQF MD + V G  FC GGCQ IADTGTSLIAGP+ EVT IN+++GGTPI  GEYM+ C  I  LP IDF+LGGKKF+LEGKDY++++ A+GKT+CLSGF+G+D+PPP GP+WILGDVFIGRFYTEFD+ NNRVGFA+AK
Sbjct:    2 VMLFTALLISAFCGVLSGSGNLVRVPLTKIQSARRTFQEVGTAIEQLSLKYAGNAEGPFPEPLSNYLDAQYYGPITLGNPPQSFRVVFDTGSSNLWVPSKKCSKLNIACWVHRKYDSSQSKTYVPNGQKFAIAYGSGSLSGYLSEDNLSIGGITIANQTFAEAINEPGMVFVAAKFDGILGLGYDTISVDKVTPPFYNMYQQGVVQNPVFSFYLSRDAAAAVGGEIIFGGSDPDKYSGDFTYIPVNRKGYWQFSMDSVMVSGKSFCKGGCQAIADTGTSLIAGPTEEVTAINQLIGGTPISAGEYMVSCDLIPKLPTIDFVLGGKKFSLEGKDYILRVSALGKTVCLSGFLGMDIPPPHGPLWILGDVFIGRFYTEFDLGNNRVGFAIAK 391          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|478486834|gb|AGJ03549.1| (cathepsin D [Palaemon carinicauda])

HSP 1 Score: 557.755 bits (1436), Expect = 0.000e+0
Identity = 261/366 (71.31%), Postives = 303/366 (82.79%), Query Frame = 0

Query:   68 RIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTK--FCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVA 431
            RIP+ K K+AR+  +EV TS++++RRRW   GP  EPLSNY+DAQYYGPI+IGTPPQSF VVFDTGSSNLWVPS+QCH+TNIACL+HNKYDS  S TYKKNG +FAIQYGSGSLSG+LS D+VSVG + VK+Q FAE LSEPGMAFVAAKFDGILGM Y  IAV+ VTPVF NMV+Q  V +P+FSFY NR+P A  GGE+ILGGSDP +Y+GDF+YV V REGYWQFKMDG+ + G    FC+GGC+ IADTGTSLIA PS E   INK +G  PIVGGE+M+DC  I +LP I F++ GK FTLEGKDY++++   GKT CLSGF+GLDVPPPMGPIWILGDVFIGRFYTEFDM NNRVGFA A
Sbjct:   20 RIPLRKFKTARQSLREVDTSINLIRRRWGNTGPMPEPLSNYMDAQYYGPISIGTPPQSFRVVFDTGSSNLWVPSKQCHFTNIACLIHNKYDSRKSSTYKKNGTEFAIQYGSGSLSGYLSTDIVSVGSVAVKDQTFAEVLSEPGMAFVAAKFDGILGMAYDRIAVDGVTPVFYNMVSQKLVPAPVFSFYPNRDPSAPEGGELILGGSDPKYYKGDFTYVSVDREGYWQFKMDGMKMNGVDVPFCNGGCEAIADTGTSLIAAPSEEARLINKKIGAKPIVGGEWMVDCSLIPNLPTISFVMNGKPFTLEGKDYILRVSQFGKTTCLSGFIGLDVPPPMGPIWILGDVFIGRFYTEFDMGNNRVGFATA 385          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|498969046|ref|XP_004526463.1| (lysosomal aspartic protease [Ceratitis capitata])

HSP 1 Score: 556.984 bits (1434), Expect = 0.000e+0
Identity = 255/368 (69.29%), Postives = 306/368 (83.15%), Query Frame = 0

Query:   65 HLVRIPVTKIKSARRHFQEVGTSLDVVRRRWSKNGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVAK 432
             L+R+P+ KIK+AR HF EVGT L  +R +++  G   EPLSNYLDAQYYGPITIG+PPQSF VVFDTGSSNLWVPS++CH TNIACL+HNKYDS  SKTY+KNG +FAI YGSGSLSG+LS D+V++GGID+K Q+FAEA+SEPG+ FVAAKFDGILG+ Y +I+V+ V P F NM  QG + +P+FSFYLNR+P A  GGEII GGSDP+HY GDF+Y+PVTR+ YWQ KMD  SVG  + C GGCQVIADTGTSLIAGP+ E T IN+ +GGTPI+GG+YM+ C  I  LP I F+LGGK F LEGKDYV++I  MGKTICLSGFMG+D+PPP GP+WILGDVFIG++YTEFDM N+RVGFA+AK
Sbjct:   19 ELLRVPLKKIKTARHHFSEVGTELHQLRIKYANGGIAPEPLSNYLDAQYYGPITIGSPPQSFKVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDSDKSKTYEKNGTEFAIHYGSGSLSGYLSADIVNIGGIDIKKQIFAEAMSEPGLVFVAAKFDGILGLAYNSISVDGVKPPFYNMYEQGLIPAPVFSFYLNRDPAAPEGGEIIFGGSDPEHYTGDFTYLPVTRKAYWQIKMDSASVGDLQLCKGGCQVIADTGTSLIAGPTQETTAINQAIGGTPIMGGQYMVSCDMIPKLPVIKFVLGGKTFELEGKDYVLRIAQMGKTICLSGFMGMDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVGFAIAK 386          

BLAST of lysosomal aspartic protease vs. nr
Match: gi|347451476|gb|AEO94539.1| (aspartate protease cathepsin D [Triatoma infestans])

HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0
Identity = 262/381 (68.77%), Postives = 315/381 (82.68%), Query Frame = 0

Query:   56 VLMGCGMADHLVRIPVTKIKSARRHFQEVGTSLDVVRRRWSK----NGPHVEPLSNYLDAQYYGPITIGTPPQSFMVVFDTGSSNLWVPSRQCHYTNIACLLHNKYDSGASKTYKKNGKKFAIQYGSGSLSGFLSQDLVSVGGIDVKNQVFAEALSEPGMAFVAAKFDGILGMGYPNIAVNKVTPVFNNMVAQGTVESPIFSFYLNRNPEAEVGGEIILGGSDPDHYEGDFSYVPVTREGYWQFKMDGLSVGGTKFCSGGCQVIADTGTSLIAGPSVEVTKINKMLGGTPIVGGEYMLDCKKIDSLPKIDFILGGKKFTLEGKDYVMQIKAMGKTICLSGFMGLDVPPPMGPIWILGDVFIGRFYTEFDMKNNRVGFAVAK 432
            VL+G   +D+LVR+P+TKI+SARR FQ+VGT+++ +  ++       GP  EPLSNYLDAQYYG IT+G+PPQSF VVFDTGSSNLWVPS++C   NIAC +H KYDS  SKTY  NG+KFAIQYGSGSLSGFLSQD +S+GG+ V NQ FAEA++EPGM FVAAKFDGILG+GY  I+V+KVTP F NM  QG V++P+FSFYLNR+P A VGGEII GGSDP+ Y GDF+YVPV ++GYWQF MD + V G  FC GGCQ IADTGTSLIAGP+ +V  +NK+LGGTPI GGEYM+ C  I  LPKIDF++GG KF+LEGKDY++++ AMGKTICLSGF+GLDVPPP GP+WILGDVFIGRFYTEFD+ NNRVGFA++K
Sbjct:   15 VLLG---SDNLVRVPLTKIQSARRFFQDVGTAVEQLTLKYDTGNGVEGPFPEPLSNYLDAQYYGAITLGSPPQSFRVVFDTGSSNLWVPSKKCSRFNIACWVHRKYDSSNSKTYVPNGEKFAIQYGSGSLSGFLSQDQLSIGGVTVANQTFAEAVNEPGMVFVAAKFDGILGLGYDTISVDKVTPPFYNMYQQGAVQNPVFSFYLNRDPAAAVGGEIIFGGSDPEKYVGDFTYVPVDKQGYWQFNMDKVIVNGKTFCKGGCQAIADTGTSLIAGPTEDVIALNKLLGGTPIAGGEYMISCDLIPKLPKIDFVIGGNKFSLEGKDYILRVSAMGKTICLSGFLGLDVPPPHGPLWILGDVFIGRFYTEFDLGNNRVGFALSK 392