voltage-dependent calcium channel type a subunit alpha-1 isoform x7, maker-scaffold210_size256293-snap-gene-1.25 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000008334 (supercontig:LSalAtl2s:LSalAtl2s508:27226:174463:1 gene:EMLSAG00000008334 transcript:EMLSAT00000008334 description:"maker-LSalAtl2s508-snap-gene-1.26") HSP 1 Score: 833.173 bits (2151), Expect = 0.000e+0 Identity = 484/645 (75.04%), Postives = 552/645 (85.58%), Query Frame = 0
Query: 61 YAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQ--AEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLML 691
YAEF+FL FILE+ IR+YALG +F+++FN FD VI GS++EV WV+F D+ GSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSI+SLLFLLFLFIFIFALLGMQ+FGGSFNF TPTSNFNTI +ALLTVFQVLTGEDWNQVMYTAI+SKGGR GGM+YSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKER K + D +DK ++ DPI+AAE+AFE+AAEAAA+AA Q ++EE +PILPYSSFFILSS+NP+RV +HW+ TKKVFD FIM +IVLSSIALASEDPVDE+S RNK+LGYADYGFT IFTLECSLK++DLGFVLHPGAY+RDFWNF+DITVV+CALISFYHT+AGTPTGQ+LKSLKLLRVLRPLKTINR+P+LKAVFDCVVISLKN IFA+VGVQLFNGKFF+C+DES+ DECQGY++ E P ++ER WE++ F+YDNCF A++TLFA+QT +LQDSM+STYE EGP PW+RVEMSIFYIVFF+VFPFFFVNIFVALIIVTFNELGEAELQD+MDKNQKSCIDFAIQARPLELYVP T G +H W+L+TS PFENFI++LI+CNTILLML
Sbjct: 379 YAEFIFLGCFILEILIRLYALGPRTYFSTTFNVFDCFVIVGSIVEVIWVHFKDKGGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSIVSLLFLLFLFIFIFALLGMQIFGGSFNFSTGTPTSNFNTITSALLTVFQVLTGEDWNQVMYTAIDSKGGRKGGGMVYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERHKTTLSDDIFLDMEVHDDKENKKYFDPIKAAEIAFEKAAEAAAKAATQEITIDQEENISIKPILPYSSFFILSSSNPIRVSIHWLXTKKVFDCFIMCVIVLSSIALASEDPVDENSIRNKLLGYADYGFTTIFTLECSLKMIDLGFVLHPGAYLRDFWNFLDITVVSCALISFYHTLAGTPTGQKLKSLKLLRVLRPLKTINRVPKLKAVFDCVVISLKNVFNILIVYMLFQIIFAIVGVQLFNGKFFFCSDESRTNADECQGYYFHYEVPNETPKIVERTWERRSFHYDNCFRAIITLFAIQT------ILQDSMASTYENEGPKPWYRVEMSIFYIVFFVVFPFFFVNIFVALIIVTFNELGEAELQDNMDKNQKSCIDFAIQARPLELYVPQRTDGFYYHAWRLITSSPFENFIMVLIICNTILLML 1017 HSP 2 Score: 93.9745 bits (232), Expect = 1.264e-19 Identity = 158/651 (24.27%), Postives = 251/651 (38.56%), Query Frame = 0
Query: 319 RAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALI------SFYHTIAGTPTGQRLKSLKLLRVLRPL--KTINRIPQLKAVFDCVVISLKNFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFN----YDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALII-------------VTFNELGEAE-LQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLF-GSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIM---LDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTY-VYFVSFIFLCSFIMLNLFVAVIMDNFD 936
R L E+ E + P SS F LS NP+R V W V VF+ I+ I+ + I +A + P + S + L + F IFT+E KI+ GF+LH G+Y+R+ WN MD VV I SF H S L L P K N P L + V+ + V + G + + C Y + P + + W P N +DN +AMLT+F QT+ D++ + + W IF+I IV FF +N+F+ ++ V F +L E + L+ +++ QK+ I+ + + F W+ + F FI L Y +F F +E + +L + GPR YF ++N FD +VGSI++ ++ V F + L L + + + SL+ L ++AI + + A++GMQ+F GS GT +NF +L+ +F+ TGE W +M +D+ GR G + Y +YFV + +LN+F+A+ D+ D
Sbjct: 35 RTHLVMEKSLEMKLHHPNKLPSSLFFLSGKNPIRRAVIWFVRWIVFEWIIIFTIIANCIVMALDQHLPHKDKSKLSVQLEELEPVFMGIFTMEMCFKIVADGFILHHGSYLRNPWNIMDFIVVISGSIYVHPNKSFIHISHYNDVIYYFYSTSFLPYLIPKSDKKENTGPDLSTLRTFRVLRPLKLVSGVPNRIITGG----------DSGNPC----YRGSSKHSP---VGKKW-VGPNNGITSFDNIGLAMLTVF--QTN--------DALGNLFN------W------IFFIPLIIVGSFFMLNLFLGVLSGEFAKEKERVESRVGFMQLKEQQKLEKELNGVQKT--HKFIKENEQTSFKKEFDDDSNF--WR--SERQFRFFIRL-------------------------YAEFIFLGCFILEILIRLYALGPRTYFSTTFNVFDCFVIVGSIVE---VIWVHFKDKGGSFGLSALRALRLLRVFKVTKYWSSLR----NLVIALMNAISSIVSLLFLLFLFIFIF-----ALLGMQIFGGSFNFSTGTPT---SNFNTITSALLTVFQVLTGEDWNQVMYTAIDSKGGRK---------------------GGGMVYSLYFVMLTLCGDYTLLNVFLAIACDSLD 578 HSP 3 Score: 56.6102 bits (135), Expect = 3.240e-8 Identity = 187/932 (20.06%), Postives = 337/932 (36.16%), Query Frame = 0
Query: 31 WFVIALVFLNTCTVAVE----HYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFD-VMVITGS-----------------VLEVFW--------VNFHDRAGSFG--LSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALIS----FYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNFIFAVV----------------GVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNEL-------------GEAELQDDM--------DKNQKSCID-----------------------------FAIQARPL----ELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDI----LSYFNLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDFITVVGSIIDATKMVS-------VGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLF-FIYAIVGMQLFGS 836
W +I + N +A++ H ++ K L+ L E +F+ F +EMC ++ A G + ++ + +N D ++VI+GS V+ F+ + D+ + G LS LR R+LR K+ S + N +I ++ + G + P TS F+ I A+LTVFQ A G + ++F+ L + G + +LN+FL + A+E E+ + QL +E + E+E++ ++ + + + + + E +++ R +++ F FI L YA++ F F LE +++ LG P Y +N D V+ +++ + G+ L++L+LLRV + K + + L VI+L N I ++V G+Q+F G F + T TP N++ A+LT+F V T E W V+ ++ S +G + S+++++ + + +N+F+A+ + ++ + L DD+ DK K D I +P+ ++ ++ R I L T + F+ FI+ +IV ++I L + P+ I L Y + FT +FT+EC K++ G P Y RD WN D V ++I ++ + LKL R R +K + R ++ + V SLK + +++ MLF I+AIVG+QLF
Sbjct: 82 WIIIFTIIANCIVMALDQHLPHKDKSK-LSVQLEELEPVFMGIFTMEMCFKIVADGFILHHGSYLRNPWNIMDFIVVISGSIYVHPNKSFIHISHYNDVIYYFYSTSFLPYLIPKSDKKENTGPDLSTLRTFRVLRPLKLV---SGVPNRIITGGDSGNPCYR------------GSSKHSPVGKKWVGPNNGITS-FDNIGLAMLTVFQT------------------NDALGNLFNWIFFIPLIIVGSFFMLNLFLGVLSGEF--------AKEKERVESRVGFMQL-------KEQQKLEKELNGVQKTH----KFIKENEQTSFKKEFDDDSNFWR-------------------------SERQFRFFIRL--------------------------YAEFIFLGCFILEILIRLYALG----PRTYFSTTFNVFDCFVIVGSIVEVIWVHFKDKGGSFGLSALRALRLLRVFKVTKYWSSLRNL-------VIALMNAISSIVSLLFLLFLFIFIFALLGMQIFGGSFNFSTG----TPTS---------------------------NFNTITSALLTVFQVLTGEDWNQVMYTAIDSKGGRKGG----GMVYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERHKTTLSDDIFLDMEVHDDKENKKYFDPIKAAEIAFEKAAEAAAKAATQEITIDQEENISIKPILPYSSFFILSSSNPIRVSIHWLXTKKVFDCFIMCVIVLSSIALASE---DPVDENSIRNKLLGYADYGFTTIFTLECSLKMIDLGFVLHPGAYLRDFWNFLDITVVSCALISFYHTLAGTPTGQKLKSLKLLRVLRPLKTINRVPKLKAVFDCVVISLKNV---------------------FNILIVYMLFQIIFAIVGVQLFNG 838
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000005510 (supercontig:LSalAtl2s:LSalAtl2s297:203090:236595:1 gene:EMLSAG00000005510 transcript:EMLSAT00000005510 description:"maker-LSalAtl2s297-augustus-gene-2.17") HSP 1 Score: 758.444 bits (1957), Expect = 0.000e+0 Identity = 431/629 (68.52%), Postives = 497/629 (79.01%), Query Frame = 0
Query: 23 ICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDKSPEEEI-DPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQG-YFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQDDMDKNQ 637
+CK +WFW VI LVFLNTCTVAVEHYNQP+WLT FLYYAEFLFL AF+ EMCIR+YALG +F+S+FNRFD +VITGS+ EV WVN RAGSFGLS LRALRLLRVFKVTKYWS LRNLVIALMNA+SSI+SLLFLLFLFIFIFALLGMQLFGGSFNFP+ETPTSNFNTI+ ALLTVFQVLT EDWN VMY AI S+GGR NGG+IYS+YFVMLTL G+Y LLNVFLAIACDSLDQAA LT AEEAEKERQ++ E+ +++ + + ++ D +R E E E + ++E++ RPILPYSS FIL+STNP RV +HW VTK FD FIM++I+LSS +LA+EDPV+E PRN +L Y DY FTAIF +EC LKILDLG HPG+Y+RD WN +D VV+CALISFY GTP GQ+LKS+KLLRVLRPLK +NR+P LKAVFDCVV SLKN IFA+VGVQLFNGKFFYC+D SK +ECQG YF E E P V R W+ K FNYDNC A++TLFAVQTSEGWV VLQ+SMSST+E+EGP PWF EM+IFYIV+F+VFPFFFVNIFVAL+IVTFNELGEAEL DD+DKNQ
Sbjct: 1 MCKQQWWFWLVIILVFLNTCTVAVEHYNQPQWLTIFLYYAEFLFLGAFVFEMCIRLYALGPFIYFSSAFNRFDCVVITGSIFEVLWVNLQPRAGSFGLSGLRALRLLRVFKVTKYWSPLRNLVIALMNALSSIMSLLFLLFLFIFIFALLGMQLFGGSFNFPDETPTSNFNTIINALLTVFQVLTEEDWNNVMYXAIVSQGGRHNGGIIYSIYFVMLTLLGNYCLLNVFLAIACDSLDQAAELTAAEEAEKERQEEEQERQRLREQQELKAIGADGQLGDELRGDE---EEGGEPP------LPDMDDEDQVRPILPYSSLFILTSTNPFRVGLHWFVTKPFFDGFIMIVILLSSASLAAEDPVEEHHPRNLLLQYFDYVFTAIFAIECLLKILDLGACAHPGSYLRDIWNVLDSLVVSCALISFY--FQGTPMGQKLKSVKLLRVLRPLKMVNRVPALKAVFDCVVTSLKNVFNILIVYMLFLLIFAMVGVQLFNGKFFYCSDASKGNAEECQGEYFVFGEHGETSPTVERRVWDIKAFNYDNCGAAIITLFAVQTSEGWVDVLQNSMSSTFEDEGPFPWFSTEMAIFYIVYFVVFPFFFVNIFVALVIVTFNELGEAELTDDIDKNQ 618 HSP 2 Score: 237.654 bits (605), Expect = 1.650e-64 Identity = 226/819 (27.59%), Postives = 370/819 (45.18%), Query Frame = 0
Query: 397 YADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFY----HTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNFIFAVV----------------GVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSM-SSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFN--------------------------------------ELGEAELQDDMDKNQKSCI---DFAIQARPL----ELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDIL-SYFNLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDFITVVGSIID--------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFF-IYAIVGMQLFGSVMI------------------------DPGTTIDRHN------NFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFI--NTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKRE-KIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIEVLRQ 1102
YA++ F F E +++ LG P Y +N D V+T ++ AG+ L++L+LLRV + K + + L VI+L N + +++ G+QLF G F + PDE N++ A+LT+F V T E W V+ ++ S G I + SI++++ ++ + +N+F+A+ + + +LG+ EL+ D ++ + + D Q RP+ L++ T+ R + VT F+ FI+++I+ ++ L + + ++L YF+ VFT +F +EC+ K++ G P +Y RD WN D + V ++I K+ SV KL R R +K++ R +++ + V SLK + +++ MLF I+A+VG+QLF + T++R N+ + +++ LF T E W D++ ++ S +T E S+ ++++ + + F +N+FVA+++ F+ L G L + I N + GKIHYT++F +L+ IDPPLG+G KCP+ +AYK+L+RMNMP+D EGKVHF TTLFAL+R NL+I +R + EMDQAD ELRTTI + WP TKR+ K++LLVP TG LTVGK++GG+LI +NWK TKFG V ++
Sbjct: 39 YAEFLFLGAFVFEMCIRLYALG----PFIYFSSAFNRFDCVVITGSIFEVLWVNLQPRAGSFGLSGLRALRLLRVFKVTKYWSPLRNL-------VIALMNALSSIMSLLFLLFLFIFIFALLGMQLFGGSFNF--------PDETPTS-----------------------NFNTIINALLTVFQVLTEEDWNNVMYXAIVSQGGRHNGGIIY-----SIYFVMLTLLGNYCLLNVFLAIACDSLDQAAELTAAEEAEKERQEEEQERQRLREQQELKAIGADGQLGD-ELRGDEEEGGEPPLPDMDDEDQVRPILPYSSLFILTSTNPFRVGLHWFVTKPFFDGFIMIVILLSSASLAAEDPVEEHHPRNLLLQYFDYVFTAIFAIECLLKILDLGACAHPGSYLRDIWNVLDSLVVSCALISFYFQGTPMGQKLKSV---KLLRVLRPLKMVNRVPALKAVFDCVVTSLKNV---------------------FNILIVYMLFLLIFAMVGVQLFNGKFFYCSDASKGNAEECQGEYFVFGEHGETSPTVERRVWDIKAFNYDNCGAAIITLFAVQTSEGWVDVLQNSMS-------------STFEDEGPFPWFSTEMAIFYIVYFVVFPFFFVNIFVALVIVTFNEL-------GEAELTDDIDKNQLRQQESWNGGKIHYTDMFALLKQIDPPLGFGSKCPDLLAYKRLVRMNMPVDNEGKVHFNTTLFALVRVNLQIFMRSTDEMDQADQELRTTIGRSWPFTKRDGKLDLLVPPSSETGPNKLTVGKIFGGMLILENWKITKFGSTPVTKK 765 HSP 3 Score: 63.929 bits (154), Expect = 2.040e-10 Identity = 66/268 (24.63%), Postives = 118/268 (44.03%), Query Frame = 0
Query: 677 FILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID------ATKMVSVGF--LKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFD 936
+++L+ NT + ++ + P + T L Y +F F E +L + GP YF ++N FD + + GSI + + S G L+ R R+ K+ + +R L+ + ALS+I + + L+ + FI+A++GMQLFG P T +NF +L+ +F+ T E W ++M A + + + G +Y +YFV L ++ +LN+F+A+ D+ D
Sbjct: 10 LVIILVFLNTCTVAVEHYNQPQWLTIFLYYAEFLFLGAFVFEMCIRLYALGPFIYFSSAFNRFDCVVITGSIFEVLWVNLQPRAGSFGLSGLRALRLLRVFKVTKYWSPLRNLVIALMN------------ALSSIMS--------LLFLLFLFIFIFALLGMQLFGGSFNFPDETPT--SNFNTIINALLTVFQVLTEEDWNNVMYXA--------IVSQGGRHNGGIIYS---------IYFVMLTLLGNYCLLNVFLAIACDSLD 238
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000010843 (supercontig:LSalAtl2s:LSalAtl2s721:13130:108134:1 gene:EMLSAG00000010843 transcript:EMLSAT00000010843 description:"maker-LSalAtl2s721-augustus-gene-1.27") HSP 1 Score: 729.169 bits (1881), Expect = 0.000e+0 Identity = 426/1012 (42.09%), Postives = 610/1012 (60.28%), Query Frame = 0
Query: 136 KYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF-----NFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQ-------LLNKDKAPEEDKSPEEEIDPIRAAEMAFERAA-----------------EAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRE-RPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID--------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTG---HLTVGKLYGGILIYDNWKKTK 1093
+YW L+NL+ +L+N+I +I+SLL LLFLF+ IFALLG Q+FGG + + +NF++ +LL+VFQ+LTGEDWN VMY I + GG + G++ SLYF++L +CG+Y LLNVFLAIA D+L A AL +EAEKE E +L + D +D + E + A E + L+ + E + PI S+F+I N R+L H+I F +++ I++SS LA+EDP++ +S RNKIL Y DY FT IFT+E LK++ GF+LHPGA+ R +N +D+ VV +LISF + +K L++LRVLRPL+ INR LK V CV+++ K F+FAV+GVQLF GKFF C+D+SK T + C+G F + +D + P+V ER WE+ F+YDN +LTLF V T EGW +L S+ S E+ GPI +R +++FY ++ I+ FF VNIFV +IVTF GE+ ++ ++DKNQ++CI+FA+ A+P+ Y+P ++ +W VTS FE I +I+ NT+ L +KF+ P +T L N++FT+ FT+E +FKL +F +NYF D WN+FDFI V+GS+ID M+S+ F +LFR RL+KLL + +R LL+TF +S QALP+V +L+G++FFIY +VGMQ+FG + G+ I+R+NNF+ F Q+L++LFR ATGEAW +IML + D + E ++ G P CG+ Y YF+SF +CSF++LNLFVAVIMDNFDYLTRD SILG HHL EF+ WS YDP G+I + ++ +LR I PPLG+GK CP R+A K+L+ MNMP++ +G V+F TLFAL+R +L I + +D+A+ ELR I+K W T + ++ + P G G +TVGK Y LI D +++ K
Sbjct: 783 RYWKRLQNLLGSLINSIXAIVSLLVLLFLFLGIFALLGTQVFGGKYVQSKSSGKNHYSRANFDSFSQSLLSVFQILTGEDWNVVMYDGIQAFGGVNSIGIVSSLYFIILFICGNYILLNVFLAIAVDNLADADAL--EDEAEKEEGAGPPEDGGVEGVDILGANSHCGGDTELRLSLDQEYSLEDYDQYAEDDEIVGDDDDEEDEGQFELDDKNTLRMDSESPFYKVVPIPQESAFYIFPPNNQFRILCHFICNHSYFGNIVLVCIMVSSAMLAAEDPLNSNSERNKILNYFDYFFTTIFTIEVCLKVISYGFLLHPGAFCRSGFNLLDLLVVAVSLISFIFSSGAISV---VKILRVLRVLRPLRAINRAKGLKHVVQCVIVAXKTIGNIVLVTLLLQFMFAVIGVQLFKGKFFMCSDKSKMTAETCRGKFIVYKDGDLNQPIVEERIWERNDFHYDNVGKGLLTLFVVSTFEGWPGILYVSIDSNAEDVGPIHNYRPIVAVFYFIYIIIIAFFMVNIFVGFVIVTFQNEGESAYKNCELDKNQRNCIEFALNAKPVRRYIPKNPI--QYKLWAFVTSPVFEYTIFAMILINTLSLAMKFYQQPQTYTAFLDVLNVIFTVFFTLEFVFKLGAFRFKNYFGDPWNSFDFIIVLGSLIDIAMAELNPGNNMISINFFRLFRVMRLVKLLSKGEGIRTLLWTFFKSF--------------------QALPWVAILIGLIFFIYGVVGMQVFGKIAPQEGSNINRNNNFQTFLQALLVLFRSATGEAWQEIMLSCR--KHPDVICDERSEDRGNP---GGCGTDFAYPYFISFFVVCSFLILNLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPDAKGRIKHVDVVTLLRKISPPLGFGKLCPHRVACKRLVSMNMPLNSDGSVNFNATLFALVRTSLSI--KTEGNIDEANEELRHQILKIWKRTDLKLLDQICP-----GAGLEDEVTVGKFYATFLIQDYFRRFK 1755 HSP 2 Score: 189.119 bits (479), Expect = 9.219e-49 Identity = 99/201 (49.25%), Postives = 132/201 (65.67%), Query Frame = 0
Query: 4 EANKRVTRSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQ 204
+ K + + +R R R+I K+ FW +I LVFLNTC +A EHY QP WL +F + F+ F EM ++MY+LG +F S FNRFD V+ S+LE+ N + GLS LR +RLLR FKVT+YWSS+ NLV +L+N+I+SI SLL +LFLFIFIF+LLGMQ+FGG F E+ S+F+T + LTVFQ
Sbjct: 578 KKKKALEKLNRRARRVCRKIVKSXAMFWIIIILVFLNTCVLATEHYKQPIWLDDFQEFTNLFFVVLFTFEMFLKMYSLGFQGYFVSLFNRFDCFVVISSILELILTN-ENIMPPLGLSVLRCVRLLRTFKVTRYWSSMGNLVKSLVNSIASINSLLVILFLFIFIFSLLGMQIFGGKFTKSLES-RSHFDTFPQSCLTVFQ 776 HSP 3 Score: 102.064 bits (253), Expect = 5.558e-22 Identity = 88/306 (28.76%), Postives = 142/306 (46.41%), Query Frame = 0
Query: 341 SFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALA--SEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGT--PTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFN-ELGEAELQDDMDK 635
S + + NP+R V K F+ I+L I+ + +ALA + P ++ + N+IL +Y F IFT EC +KI+ GF HP AY+R WN +D T+V +IS TI + G +K+L+ RVLRPL+ ++ +P+ D + G + C DE GY V WE F N+D+ ++MLT+F T EGW VL QD+M S+++ I+++ ++ FF +N+ + ++ F+ E +A+ + D K
Sbjct: 151 SIYCWTIKNPIRKRFIQFVEWKPFEFLILLTILGNCVALAIYTPFPAEDTNETNQILEKVEYIFLVIFTTECVMKIIAYGFWQHPTAYLRSAWNMLDFTIVMIGVIS---TILSSLRIEGFDVKALRAFRVLRPLRLVSGVPREMEETDNPTLC---------------GGNYKC--------DEEAGY------------VCREYWEGPNFGITNFDHFGLSMLTVFQCITLEGWTDVLYWVQDAMGSSWQ------------FIYFVSXVVLGAFFVMNLILGVLSGEFSKEREKAQSRGDFQK 406 HSP 4 Score: 97.0561 bits (240), Expect = 2.171e-20 Identity = 64/252 (25.40%), Postives = 122/252 (48.41%), Query Frame = 0
Query: 26 TSYWFWFVI-ALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEE----TPTSNFNTIVAALLTVFQVLTGEDWNQVMYTA-----------INSKGGRANGGMIYSL-YFVMLTLCGDYTLLNVFLAIACDSLD 260
TS F + I A++ +NT ++A++ Y QP+ T FL +F F LE ++ A +F +N FD +++ GS++++ + ++ R R++R+ K+ +R L+ + ++ + L+ L FI+ ++GMQ+FG P+E +NF T + ALL +F+ TGE W ++M + +G G ++ YF+ + + +LN+F+A+ D+ D
Sbjct: 1353 TSPVFEYTIFAMILINTLSLAMKFYQQPQTYTAFLDVLNVIFTVFFTLEFVFKLGAFRFKNYFGDPWNSFDFIIVLGSLIDIAMAELNPGNNMISINFFRLFRVMRLVKLLSKGEGIRTLLWTFFKSFQALPWVAILIGLIFFIYGVVGMQVFGKI--APQEGSNINRNNNFQTFLQALLVLFRSATGEAWQEIMLSCRKHPDVICDERSEDRGNPGGCGTDFAYPYFISFFVVCSFLILNLFVAVIMDNFD 1602 HSP 5 Score: 73.559 bits (179), Expect = 2.654e-13 Identity = 60/248 (24.19%), Postives = 113/248 (45.56%), Query Frame = 0
Query: 14 KRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEH-YNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGL-SALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF--------------------------NFP------EETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKG 223
+ R IC SY+ V+ + +++ +A E N + L Y ++ F + F +E+C+++ + G + AF S FN D++V+ S+ ++F +G+ + LR LR+LR + L+++V ++ A +I +++ + L F+FA++G+QLF G F N P E +++ + LLT+F V T E W ++Y +I+S
Sbjct: 1023 NQFRILCHFICNHSYFGNIVLVCIMVSSAMLAAEDPLNSNSERNKILNYFDYFFTTIFTIEVCLKVISYGFLLHPGAFCRSGFNLLDLLVVAVSL-----ISFIFSSGAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAXKTIGNIVLVTLLLQFMFAVIGVQLFKGKFFMCSDKSKMTAETCRGKFIVYKDGDLNQPIVEERIWERNDFHYDNVGKGLLTLFVVSTFEGWPGILYVSIDSNA 1265 HSP 6 Score: 68.5514 bits (166), Expect = 9.866e-12 Identity = 87/337 (25.82%), Postives = 143/337 (42.43%), Query Frame = 0
Query: 667 KLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID-------------ATKMVSVGFLKLFRAAR-------LIKLLRRSVS------VRILLYTFVQSLKVSCGTLSFG-----ALSAIKAF--FPQALPYV---------------CMLMGMLFFIYAIV----------------GMQLFGSVMIDPGTTIDRH---NNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLC-SFIMLNLFVAVIMDNF 935
K+V S I++L+ NT +L + + P++ D + NL F +LFT E K+ S G + YF +N FD V+ SI++ + + V L+ F+ R L+K L S++ V + L+ F+ SL G FG +L + F FPQ+ V +L ++ I AIV G Q+FG + ++ H NF F QSL+ +F+ TGE W +M D + G V + G ++ +YF+ +F+C ++I+LN+F+A+ +DN
Sbjct: 596 KIVKSXAMFWIIIILVFLNTCVLATEHYKQPIWLDDFQEFTNLFFVVLFTFEMFLKMYSLGFQGYFVSLFNRFDCFVVISSILELILTNENIMPPLGLSVLRCVRLLRTFKVTRYWSSMGNLVKSLVNSIASINSLLVILFLFIFIFSL---LGMQIFGGKFTKSLESRSHFDTFPQSCLTVFQGFEDSERYWKRLQNLLGSLINSIXAIVSLLVLLFLFLGIFALLGTQVFGGKYVQSKSSGKNHYSRANFDSFSQSLLSVFQILTGEDWNVVMYDG------------IQAFGG----VNSIG-IVSSLYFI-ILFICGNYILLNVFLAIAVDNL 911 HSP 7 Score: 67.0106 bits (162), Expect = 2.628e-11 Identity = 77/286 (26.92%), Postives = 121/286 (42.31%), Query Frame = 0
Query: 667 KLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTD----ILSYFNLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDF----ITVVGSIIDATKMVSVGF-LKLFRAARLIKLLRRSVSV-RILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCM--LMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTC-GSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNF 935
+ V +PFE ILL I+ N + L + + P T+ IL +F ++FT EC+ K++++G P Y R +WN DF I V+ +I+ + ++ GF +K RA R+++ LR V R + T +L CG G + YVC G F I NF HF S++ +F+C T E W D++ +V GSS ++YFVS + L +F ++NL + V+ F
Sbjct: 167 QFVEWKPFEFLILLTILGNCVALAI-YTPFPAEDTNETNQILEKVEYIFLVIFTTECVMKIIAYGFWQHPTAYLRSAWNMLDFTIVMIGVISTILSSLRI--EGFDVKALRAFRVLRPLRLVSGVPREMEETDNPTL---CG----GNYKC-----DEEAGYVCREYWEGPNFGI-----------------------TNFDHFGLSMLTVFQCITLEGWTDVL-----------------------YWVQDAMGSSWQFIYFVSXVVLGAFFVMNLILGVLSGEF 391 HSP 8 Score: 55.4546 bits (132), Expect = 1.065e-7 Identity = 75/354 (21.19%), Postives = 142/354 (40.11%), Query Frame = 0
Query: 352 RVLVHWIVTKKVFDMFIMLIIVLSSIALASE---DPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKT--------------INRIPQLKAVFDCVVISLKNFIFAVVGVQLFNGKFFYCTDESKQ---TPDECQGYFYIVEDRER------------------------------------------PPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAE-LQDDMDKNQKS 639
R + IV I++++ L++ LA+E P+ D + + + F +FT E LK+ LGF Y +N D VV +++ T L L+ +R+LR K +N I + ++ V++ L FIF+++G+Q+F GKF + P C F ED ER V ++ K + N+D+ ++L++F + T E W +V+ D + + G + + S+++I+ FI + +N+F+A+ + + L +A+ L+D+ +K + +
Sbjct: 591 RRVCRKIVKSXAMFWIIIILVFLNTCVLATEHYKQPIWLDDFQE----FTNLFFVVLFTFEMFLKMYSLGF----QGYFVSLFNRFDCFVVISSILELILTNENIMPPLGLSVLRCVRLLRTFKVTRYWSSMGNLVKSLVNSIASINSLL--VILFLFIFIFSLLGMQIFGGKFTKSLESRSHFDTFPQSCLTVFQGFEDSERYWKRLQNLLGSLINSIXAIVSLLVLLFLFLGIFALLGTQVFGGKYVQSKSSGKNHYSRANFDSFSQSLLSVFQILTGEDWNVVMYDGIQAF----GGVNSIGIVSSLYFIILFICGNYILLNVFLAIAV---DNLADADALEDEAEKEEGA 927
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000004952 (supercontig:LSalAtl2s:LSalAtl2s260:1045447:1062229:1 gene:EMLSAG00000004952 transcript:EMLSAT00000004952 description:"maker-LSalAtl2s260-snap-gene-10.24") HSP 1 Score: 682.945 bits (1761), Expect = 0.000e+0 Identity = 430/1086 (39.59%), Postives = 602/1086 (55.43%), Query Frame = 0
Query: 86 FFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANG-GMIYSLYFVMLTLCGDYTLLNVFLAIACDSL--------DQAAALTEAEEAEKERQKQAAEQLLNKDKAPEE----------------DKSPEEEIDPIRAA----------EMAFERAAEAAARAALQAEE-------EEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISF-YHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVIS------------LKNFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRE-RPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID---------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLA-IELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGT--GHLTVGKLYGGILIYDNWKKTKFGQIEVLRQ 1102
+F S FNRFD V+ S+LE+ H G+S LR +RLLR FKVT+YW+SL+NL+ +L+N+I +I SL+ LLFLF+ I+ALLG QLFGG F ++LTGEDWN VMY I + GG GM SLYF+ L + G+Y LLNVFLAIA D+L + + + E A Q+ + + P E D E+E +P + +M + L+ E+ E+++ ++ PI P+SS FI S TN RVL + F FI++ I++SS +LA+EDP+ SPRN ++ Y G V H GAY R N +D+ VV+ ++IS + AG + LK L++LRVLRPL+ +NR LK V V++S L F+FAV+GVQLF GKF+ C+D SK T +ECQG + + + P V+ER W F+YDN MLTLF V T EGW +L S+ S E+ GP+P R M IFYIV+ I+ FF VNIFV +IVTF + GE+ + ++DKNQ++CID+ + A+P LY+P + ++ IW S FE + I+ NTI L + F+ P ++D L N +FT+ F +E + K+ +F P+ YF D WNTFD I V+GS ID +S+ F +LFRA RL+KLL + S+R LL+TF++S QALPYV +L+ ++FFIY +VGMQ+FG + I+ T+I +NNF++F +L++LFR ATGEAW DIML C P +E ++ + E CGS + Y YF+SF SF++LNLFVAVIMDNFDYLTRD SILG+HHL EF+N WS YDP G I + ++ +LR I+PPLG+GK CP R A K+L+ MNMP+ +G V F TLFA+IR +L I + S ++ A+ ELR + K W ++ L+P + + VGK Y +LI D +++ + E RQ
Sbjct: 405 YFISLFNRFDCFVVLSSILELVLTRTHIMP-PLGMSVLRCIRLLRAFKVTRYWTSLKNLLKSLINSIEAIFSLIVLLFLFLGIYALLGSQLFGGKF--------------------XERILTGEDWNAVMYDGILAYGGPQTVLGMFASLYFITLFIIGNYILLNVFLAIAVDNLAGDDDDEEXETPVVKDPEPAFAPAQQDPSRPPPPGTQIPHEREDLLMMIDNHHLYNYDPGYEDEYNPYLNSNGYDHYNDYNQMVNNNGPIKSLEEKLEEEKANEEAFLEDDDNKKDPIPPFSSLFIFSPTNRFRVLCYNFCNHAYFANFILVCIMVSSASLAAEDPLHSKSPRNIVIAY--------------------GAVGHKGAYARYPANILDLVVVSVSIISIAFRDSAGAIS--VLKILRVLRVLRPLRAVNRAKGLKLVIXAVIVSVSTIQNIVLVTVLLQFLFAVIGVQLFKGKFYSCSDSSKMTEEECQGQYVDFKKSDWAQPTVLEREWSLNDFHYDNVAKGMLTLFVVSTFEGWPGILYTSLDSHAEDTGPLPISRPSMFIFYIVYIIIIAFFMVNIFVGFVIVTFQKEGESPFANCELDKNQRNCIDYTLNAKPARLYLPSDPV--QYRIWAWAXSSKFEYVVFGAILLNTISLAMSFYNQPQIYSDFLDLLNYIFTIFFALEFVIKMAAFRPKEYFCDPWNTFDCIIVIGSFIDIGMSSLGSGDGGGISINFFRLFRALRLVKLLSKDESIRTLLWTFIKSF--------------------QALPYVMLLIALVFFIYGVVGMQVFGKIAINEDTSIHSNNNFQNFQSALIVLFRSATGEAWQDIMLS------CIPSPDVECDEESEEAGNPAGCGSIIAYPYFISFFIATSFLILNLFVAVIMDNFDYLTRDWSILGAHHLDEFVNLWSEYDPDAKGCIKHMDVVQLLRKINPPLGFGKLCPHRNACKRLVAMNMPLRDDGTVEFQATLFAIIRTSLGIKMEGS--LEXANSELRLIMKKIW-RKDDSVLDKLIPRKRGESEFGNDVAVGKFYATVLIQDCFRRFAKKRFEKERQ 1416 HSP 2 Score: 99.3673 bits (246), Expect = 3.044e-21 Identity = 69/251 (27.49%), Postives = 124/251 (49.40%), Query Frame = 0
Query: 26 TSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEV-FWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEET---PTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINS-----------KGGRANGGMIYSL-YFVMLTLCGDYTLLNVFLAIACDSLD 260
+S + + V + LNT ++A+ YNQP+ ++FL ++F F LE I+M A +F +N FD +++ GS +++ G ++ R R LR+ K+ S+R L+ + + ++ ++ L+ L FI+ ++GMQ+F G E+T +NF +AL+ +F+ TGE W +M + I S G A G I + YF+ + + +LN+F+A+ D+ D
Sbjct: 1002 SSKFEYVVFGAILLNTISLAMSFYNQPQIYSDFLDLLNYIFTIFFALEFVIKMAAFRPKEYFCDPWNTFDCIIVIGSFIDIGMSSLGSGDGGGISINFFRLFRALRLVKLLSKDESIRTLLWTFIKSFQALPYVMLLIALVFFIYGVVGMQVF-GKIAINEDTSIHSNNNFQNFQSALIVLFRSATGEAWQDIMLSCIPSPDVECDEESEEAGNPAGCGSIIAYPYFISFFIATSFLILNLFVAVIMDNFD 1251 HSP 3 Score: 93.9745 bits (232), Expect = 1.394e-19 Identity = 80/312 (25.64%), Postives = 143/312 (45.83%), Query Frame = 0
Query: 285 NKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPV--DEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPT--GQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFFY-CTDE-----SKQTPDECQGYFYIVEDRERPPMVMERNWEKKP----FNYDNCFMAMLTLFAVQTSEGWV 570
NK + +ED + E FE+ E +A Q + + + + S ++ S NP+R+ +V K F+ FI+ I+ + ++LA P + + N L + F IFT EC +KI+ G H AY+R+ WNF+D ++V +I F + + + G +K+L+ RVLRPL+ ++ +P L+ V + +++++ I++++G+Q+F G C D P C G + + R + P N+DN ++MLT+F T EG++
Sbjct: 3 NKGQTKDEDTASE------------FEKLQEEILKATPQTKRIQVGAKPQVERIERSIYLFSLKNPIRLKCITVVEWKAFEFFILATILATCVSLALHKPYPNGDTNDLNLFLEKIEVIFMVIFTGECVIKIVAYGLYQHEEAYLRNTWNFIDFSIV---MIGFMDILLSSLSIEGFDVKALRAFRVLRPLRLVSGVPSLQVVLNAILMAIFPLFHIALLVLFVIIIYSIIGLQMFQGLMHKACFDNITGVLIDDDPRLCGGNYQCETG-------VCREYIPGPNFGITNFDNFILSMLTVFQCITLEGFM 292 HSP 4 Score: 62.003 bits (149), Expect = 9.404e-10 Identity = 74/281 (26.33%), Postives = 122/281 (43.42%), Query Frame = 0
Query: 662 RFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYF----NLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDFITVVGSIIDA--TKMVSVGF-LKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDP------GTTIDRH--------------------------NNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLY 899
R +V + FE FIL I+ + L L P T+ L+ F ++F ++FT EC+ K+V++G Y R++WN DF V+ +D + + GF +K RA R+++ LR L + V SL+V + + A FP L ++ +L+ + IY+I+G+Q+F +M G ID NF +F S++ +F+C T E + G+GR + + E KTT +Y
Sbjct: 58 RLKCITVVEWKAFEFFILATILATCVSLALH-KPYPNGDTNDLNLFLEKIEVIFMVIFTGECVIKIVAYGLYQHEEAYLRNTWNFIDFSIVMIGFMDILLSSLSIEGFDVKALRAFRVLRPLR--------LVSGVPSLQVVLNAI-------LMAIFP--LFHIALLVLFVIIIYSIIGLQMFQGLMHKACFDNITGVLIDDDPRLCGGNYQCETGVCREYIPGPNFGITNFDNFILSMLTVFQCITLEGFMTQWEAPGNGRILE-FSKERTKTTSRGIY 319 HSP 5 Score: 55.8398 bits (133), Expect = 7.832e-8 Identity = 52/248 (20.97%), Postives = 105/248 (42.34%), Query Frame = 0
Query: 14 KRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVE---HYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRF--DVMVITGSVLEVFWVNFHDRAGSFG-LSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF-------NFPEE---------------TPTS----------NFNTIVAALLTVFQVLTGEDWNQVMYTAINSKG 223
R R C +Y+ F++ + +++ ++A E H P+ + I A+G ++ R+ +++ + + + + F D AG+ L LR LR+LR + L+ ++ A++ ++S+I +++ + L F+FA++G+QLF G F EE PT +++ + +LT+F V T E W ++YT+++S
Sbjct: 689 NRFRVLCYNFCNHAYFANFILVCIMVSSASLAAEDPLHSKSPR-------------------NIVIAYGAVG----HKGAYARYPANILDLVVVSVSIISIAFRDSAGAISVLKILRVLRVLRPLRAVNRAKGLKLVIXAVIVSVSTIQNIVLVTVLLQFLFAVIGVQLFKGKFYSCSDSSKMTEEECQGQYVDFKKSDWAQPTVLEREWSLNDFHYDNVAKGMLTLFVVSTFEGWPGILYTSLDSHA 913
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000008332 (supercontig:LSalAtl2s:LSalAtl2s508:183886:232439:1 gene:EMLSAG00000008332 transcript:EMLSAT00000008332 description:"maker-LSalAtl2s508-snap-gene-1.28") HSP 1 Score: 367.466 bits (942), Expect = 8.593e-119 Identity = 183/230 (79.57%), Postives = 204/230 (88.70%), Query Frame = 0
Query: 874 MLDAGSGRPCDPLAIELNKTTGEPL-YVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIEVLRQ 1102
ML SGR CD A+E N T+G + CGSSLTY+YF+SFIF CSFIMLNLFVAVIMDNFDYLTRD+SILGSHHLGEFI TWS +DPSG G+IHYTE+FN+LR IDPPLG+GKKCPERMA+KKLIRMNMPMD EGKVHFTTTLFALIRE+LKINVRESSEMDQADIELRTTIIKCWPHTKR+KI+LLVPT K TG G+LTVGKLYGG++I++NW TKFGQIEVLR+
Sbjct: 1 MLAVLSGRSCDLKALEYNITSGTLINQEQNCGSSLTYIYFISFIFFCSFIMLNLFVAVIMDNFDYLTRDTSILGSHHLGEFITTWSEFDPSGIGRIHYTEVFNLLRSIDPPLGFGKKCPERMAFKKLIRMNMPMDTEGKVHFTTTLFALIREHLKINVRESSEMDQADIELRTTIIKCWPHTKRDKIDLLVPTAKSTGKGYLTVGKLYGGVMIHNNWCNTKFGQIEVLRR 230
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000009889 (supercontig:LSalAtl2s:LSalAtl2s643:800:51309:-1 gene:EMLSAG00000009889 transcript:EMLSAT00000009889 description:"maker-LSalAtl2s643-snap-gene-0.8") HSP 1 Score: 268.855 bits (686), Expect = 8.957e-77 Identity = 161/340 (47.35%), Postives = 202/340 (59.41%), Query Frame = 0
Query: 173 GMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNFIFAVVGVQLFNGKFF 509
GMQLFGG+FNF + TP SNFN+ +LLTVFQ+LTGEDWN+VMY I S+GG GM+YSLYF++LTL G+YTLLNVFLAIA D+ L A+E L A E + E +E ++++ +R+ VH IVT FD FIM+II++SSIALA+EDPV E+S RN IL Y DY FT IF +E LK++DLG + HPG+Y+RD WN MD VV CA ISF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN ++ LF + F
Sbjct: 498 GMQLFGGAFNFSDGTPPSNFNSFAISLLTVFQILTGEDWNEVMYQGIESQGGH-RSGMVYSLYFIILTLFGNYTLLNVFLAIAVDN------LANAQE---------------------------------------------------LTAAENQAENDE----------LVANAGQIRLFVHGIVTFPFFDTFIMIIIIMSSIALAAEDPVQENSRRNHILTYFDYVFTGIFAVEMILKVIDLGLIAHPGSYLRDVWNLMDALVVICASISFIFDMTGSSKGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVTNILIVYILFQRRVF 769 HSP 2 Score: 97.4413 bits (241), Expect = 8.690e-21 Identity = 43/64 (67.19%), Postives = 51/64 (79.69%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEM 74
R EKR+RF+IR K +++WFVI LVFLNT VAVEHYNQP+WLTE LYYAEF+FL F+ EM
Sbjct: 372 RCEKRVRFYIRHTVKQQWFYWFVIVLVFLNTLCVAVEHYNQPEWLTELLYYAEFVFLGLFLAEM 435 HSP 3 Score: 79.7221 bits (195), Expect = 2.921e-15 Identity = 61/210 (29.05%), Postives = 93/210 (44.29%), Query Frame = 0
Query: 402 FTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTP----------------------TGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKF-----------FYCTDESKQTP---DECQGYFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTL 560
F IFT+E +LKIL LGFVLH G+Y+R+ WN MD VV +++F A P G L++L+ +RVLRPLK ++ +P L+ V ++ +L IFA++G++ ++G TD S + P D+ E + NWE + ++DN AMLT+
Sbjct: 54 FLGIFTVEAALKILALGFVLHRGSYLRNAWNIMDFIVVVTGMVTFGAE-ASIPFDLTIVRSFRESEASSSSIPSEEGVDLRTLRAIRVLRPLKLVSGVPSLQVVLKSILKALAPLMQIALLVMFAILIFAIIGLEFYSGALHKACYSVENLELMVTDGSLKVPCHSDDPLTAPAGAHTCEPNVSICLENWEGPNYGITSFDNIGFAMLTV 262 HSP 4 Score: 60.8474 bits (146), Expect = 1.853e-9 Identity = 62/271 (22.88%), Postives = 114/271 (42.07%), Query Frame = 0
Query: 547 PFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALII---VTFNELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIW----------KLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDFITVVGS----IIDAT------KMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLK 790
P N+++ +++LT+F + T E W V+ + S + + S+++I+ + + +N+F+A+ + EL AE Q + D + A + L+V + P F + L +P + N+ IL+YF+ VFT +F VE I K++ G P +Y RD WN D + V+ + I D T + ++ L++ R R +K ++R ++ + V SLK
Sbjct: 514 PSNFNSFAISLLTVFQILTGEDWNEVMYQGIESQGGHRSGMVY-----SLYFIILTLFGNYTLLNVFLAIAVDNLANAQELTAAENQAEND-------ELVANAGQIRLFVHGIVTFPFFDTFIMIIIIMSSIALAAEDPVQE--------NS------------RRNHILTYFDYVFTGIFAVEMILKVIDLGLIAHPGSYLRDVWNLMDALVVICASISFIFDMTGSSKGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLK 752
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000003972 (supercontig:LSalAtl2s:LSalAtl2s2133:21116:38912:-1 gene:EMLSAG00000003972 transcript:EMLSAT00000003972 description:"maker-LSalAtl2s2133-snap-gene-0.4") HSP 1 Score: 251.906 bits (642), Expect = 2.946e-74 Identity = 137/265 (51.70%), Postives = 181/265 (68.30%), Query Frame = 0
Query: 434 MDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLI 682
MD+ VV+CA+ SF + G+ G+ L KSL++LRVLRPLKTI R+P+LKAVFDCV+ SLKN FIFAV+ VQLFNGKFFYC+D SKQ +E + YF + PP V+ R W+++ F+YDN A+LTLFAVQT+EGW +LQ SM++T+E++ PIP+FRV MSIFYIV+FIVFPFFFVNIFVALII+TF E GE+EL++ ++DK C+ L Y P ++I+ VT +++LLI
Sbjct: 1 MDMLVVSCAITSFAMDMLGSSGGENLGTMKSLRVLRVLRPLKTIKRVPKLKAVFDCVINSLKNVFNILVVYILFHFIFAVIAVQLFNGKFFYCSDASKQDAEEGE-YFLFSTVNDFPPQVLPRVWKRQRFHYDNVATAILTLFAVQTTEGWPAILQQSMAATFEDQAPIPFFRVGMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGESELEEAEIDKKSVECV------LKLISYGPGSYFKDAWNIFDFVTXFKALPYVILLI 258 HSP 2 Score: 219.935 bits (559), Expect = 5.853e-63 Identity = 110/193 (56.99%), Postives = 141/193 (73.06%), Query Frame = 0
Query: 810 QALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYV-MTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIR 1001
+ALPYV +L+ MLFFIY I+GMQ+FG++ +P T +RH NF+ F +M+LFRCATGEAWP IML +G+ D + N T+G+ L TCGSS++YVYFVSFIFLCSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL E G+I+YTE+++ML+++DPPLG+ KC + KK IR
Sbjct: 249 KALPYVILLIAMLFFIYTIIGMQIFGNIEFNPETEYNRHVNFQTFAAGIMVLFRCATGEAWPSIMLACEAGKRXDERNHKYNLTSGKILDPEKTCGSSMSYVYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDE-------------GRIYYTEMYDMLKNMDPPLGFVSKCEQ---LKKWIR 425 HSP 3 Score: 57.7658 bits (138), Expect = 1.069e-8 Identity = 51/208 (24.52%), Postives = 91/208 (43.75%), Query Frame = 0
Query: 113 DRAGSFG------LSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF-----------------------NFPEETPTS-------NFNTIVAALLTVFQVLTGEDW----NQVMYTAINSKGG----RANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQ 276
D GS G + +LR LR+LR K K L+ + ++N++ ++ ++L + LF FIFA++ +QLF G F +FP + +++ + A+LT+F V T E W Q M + R + Y +YF++ + +N+F+A+ + Q +E EEAE +++
Sbjct: 16 DMLGSSGGENLGTMKSLRVLRVLRPLKTIKRVPKLKAVFDCVINSLKNVFNILVVYILFHFIFAVIAVQLFNGKFFYCSDASKQDAEEGEYFLFSTVNDFPPQVLPRVWKRQRFHYDNVATAILTLFAVQTTEGWPAILQQSMAATFEDQAPIPFFRVGMSIFYIVYFIVFP----FFFVNIFVALIIITF-QEQGESELEEAEIDKK 218
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000008678 (supercontig:LSalAtl2s:LSalAtl2s537:391902:427693:-1 gene:EMLSAG00000008678 transcript:EMLSAT00000008678 description:"maker-LSalAtl2s537-snap-gene-3.43") HSP 1 Score: 242.662 bits (618), Expect = 9.823e-71 Identity = 140/318 (44.03%), Postives = 168/318 (52.83%), Query Frame = 0
Query: 733 RDSWNTFDFITVVGSIIDATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPL-YVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIK 1049
+D WNTFDFITVVGSI+DA L+ F ALPYVC+LM MLFFIY I+GMQ+FG++ +DP CATGEAWP IML GR CDP A+ +N+TTGE + CGS TYVYFVSFIFLCSF+MLNLF+ YD ML+++DPPLG+G KCP+R+AYKKLIRMNMP++ EGKV+FTTTLFALIRENL I +R + EMDQAD+ELR TI+K
Sbjct: 38 QDPWNTFDFITVVGSIVDA-----------------------------LMVEFA------------------------ALPYVCLLMAMLFFIYTIIGMQVFGNIKLDP---------------------ECATGEAWPSIMLSCEDGRDCDPRALHINETTGEIVDKTKKCGSGFTYVYFVSFIFLCSFLMLNLFM-------------------------------YD--------------MLKNMDPPLGFGSKCPDRLAYKKLIRMNMPLNSEGKVNFTTTLFALIRENLSIKMRAAEEMDQADVELRDTILK 236
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000006853 (supercontig:LSalAtl2s:LSalAtl2s3888:1494:5853:1 gene:EMLSAG00000006853 transcript:EMLSAT00000006853 description:"maker-LSalAtl2s3888-augustus-gene-0.2") HSP 1 Score: 234.572 bits (597), Expect = 2.010e-70 Identity = 132/193 (68.39%), Postives = 159/193 (82.38%), Query Frame = 0
Query: 74 MCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALT 266
M +RM+ALG ++ SSFNRFD +VI+GSV EV W +F +AGSFG S LRALRLLR+FKVT YWSSLRNLVI+L++++ SI+SLL LLFLFI IFALLGMQLFGG+FNFP+ TP SNFN+ A+LTVFQ+LTGEDWN+VMY I S+GG A G+IYSLYF+ LT+ G+YTLLNVFLAIA DSL QA +T
Sbjct: 1 MFLRMWALGPRIYYESSFNRFDCLVISGSVFEVVWTHFKPKAGSFGFSVLRALRLLRIFKVTAYWSSLRNLVISLLSSMKSIISLLLLLFLFILIFALLGMQLFGGTFNFPDGTPPSNFNSFSIAMLTVFQILTGEDWNEVMYQGIESQGG-AQAGLIYSLYFIFLTMFGNYTLLNVFLAIAVDSLGQAQEMT 192 HSP 2 Score: 51.6026 bits (122), Expect = 4.169e-7 Identity = 57/225 (25.33%), Postives = 97/225 (43.11%), Query Frame = 0
Query: 722 KLVSFGPRNYFRDSWNTFDFITVVGSIIDAT------KMVSVGFLKLFRAARLIKLLRRSV---SVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSF---IMLNLFVAVIMDN 934
++ + GPR Y+ S+N FD + + GS+ + K S GF + RA RL+++ + + S+R L+ + + S+K L L + A++GMQLFG P T +NF F +++ +F+ TGE W ++M IE G+ +Y + FIFL F +LN+F+A+ +D+
Sbjct: 4 RMWALGPRIYYESSFNRFDCLVISGSVFEVVWTHFKPKAGSFGF-SVLRALRLLRIFKVTAYWSSLRNLVISLLSSMKSIISLLLLLFLFILIF--------------------ALLGMQLFGGTFNFPDGT--PPSNFNSFSIAMLTVFQILTGEDWNEVMYQ----------GIESQG-----------GAQAGLIYSLYFIFLTMFGNYTLLNVFLAIAVDS 184
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Match: EMLSAG00000009714 (supercontig:LSalAtl2s:LSalAtl2s627:140867:158129:1 gene:EMLSAG00000009714 transcript:EMLSAT00000009714 description:"maker-LSalAtl2s627-snap-gene-1.23") HSP 1 Score: 229.18 bits (583), Expect = 1.874e-61 Identity = 227/914 (24.84%), Postives = 398/914 (43.54%), Query Frame = 0
Query: 37 VFLNTCTVAVEHYN--------QPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF------NFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQL-----LNKDKAPEE------DKSPEEEIDPI--RAAEMAFERAA---------------------EAAARAALQAEEEEE----------EEEERPILPYSSFFILSSTNPL-------RVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSP-RNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNEL---GEAELQDDMDKNQKSCIDFAIQARPLELY--VPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPG------TTIDRHNNFRHFFQSLMLL 861
+ +N + +HYN + L + F + F E +++ A+ FF +N FD +++ S++E+ G GLS LR+ RLLRVFK+ K W SL +++ + N + ++ +L +L + IFIFA++GMQLFG + + E P NF + + + VF+VL GE W + M+ + G YF+ L + +LN+FLA+ S E E+ + ++ A + K K EE K + P+ A F + + + A Q ++ EE E+ P Y + +P R++ ++ + F+ ++ +I+LSS + ED E P L Y D T +F LE +LK+ +G P Y + W ++D +V +LI+F ++ G K+++ LR LRPL+ ++++ +K V + ++ +L + IFA++GV LF G F C D + I+ ++ W +DN MA L L V T +GW+ ++ D++ S + P + M +++ F I+ FF +N+ V +II FNE G + L M ++QK I +A + +P P+ ++ +VT++ F+ I+ I N + +M+ + +T +L N+ F ++FT+E + K+ + + YF + WN FDF V ++S+G L L R+ +R LL++ V +L AL +C+L+ ++ FI+A+ GM LF +V I PG + ++ +FRH + L +L
Sbjct: 634 IVVNVLFMMFDHYNIEYDANGGMSMEMNNLLKNGNYFFTTIFAFESFMKLMAMSPRYFFADGWNCFDFLIVILSLVELL------AXGVNGLSMLRSFRLLRVFKLAKSWKSLNDIMTIMANTLGALSNLTVVLCIIIFIFAVMGMQLFGSFYIEKACEKWKCELPRWNFTDFLHSFMIVFRVLCGE-WIESMWACMYVAGPTC------VPYFLATVLVANLVILNLFLALLLSSFSDMGGSGEEEDGKPDKMSIAVNRFKRLFSFTKRKIKEELFDRIXRKIAHSKSKPLIPEANGNGFSHKTNGYIGGHNNVPSETQTYIPIDQQSDKFAPQTKDHEEIYYDPLETLEVEDCCPPFVYRIIPLGDQHSPFWEAWTQQRLMAMRLIENEYFEGVVLGLILLSSFVMTLEDIWFETRPVLIDCLYYLDRILTVVFFLETTLKLFAMG----PVMYFTNAWCWLDFVIVAXSLINFIASLVGAVNIPIFKTMRTLRALRPLRAMSKMEGMKVVVNALIGALPSIFNVLLVCIVFWLIFAIIGVNLFMGTFHKCIDSIXGHKFSHE----IIPNKTVCLNQTNAQWINSKVTFDNVIMAYLALLQVATWKGWITIMDDAIDSVAINKQPYREASIGMYFYFVAFIILGSFFTLNLLVGVIIDKFNEQKNKGGSSLDAFMTEDQKKYIAAMKKASKKKPLKALPRPYWKPQAIVFGIVTNKKFDMIIMGFIGLNMLTMMMDHYQQTEGWTFVLDNLNVFFIMIFTLEMLLKIFALR-QYYFSEPWNLFDFFIV---------LLSLGGLFL-----------RAKGIRTLLFSLVMALP--------------------ALGNICLLLFLVMFIFAVFGMSLFKNVKIIPGFDDEFDPSGSQYISFRHLSEFLDVL 1485 HSP 2 Score: 83.1889 bits (204), Expect = 3.174e-16 Identity = 113/523 (21.61%), Postives = 212/523 (40.54%), Query Frame = 0
Query: 17 RFFIRRICKTSYWFWFVIALVFLNTCTVAVEH--YNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFN---------------FPEETPTSN------------FNTIVAALLTVFQVLTGEDWNQVMYTAINSKG------GRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNFIFAVVGVQLF 504
R R+ + Y+ V+ L+ L++ + +E + L + LYY + + F LE ++++A+G + +F +++ D +++ S++ F + +R LR LR + ++ +V AL+ A+ SI ++L + +F IFA++G+ LF G+F+ P +T N F+ ++ A L + QV T + W +M AI+S A+ GM + YFV + G + LN+ + + D ++ +K + + + + +D+ + + A ++ +++ LP + P ++ + KK FDM IM I L+ + + D + +L + F IFTLE LKI L Y + WN D +V +L + R K ++ L + +P L + C+++ L FIFAV G+ LF
Sbjct: 1001 RLMAMRLIENEYFEGVVLGLILLSSFVMTLEDIWFETRPVLIDCLYYLDRILTVVFFLETTLKLFAMGPVMYFTNAWCWLDFVIVAXSLIN-FIASLVGAVNIPIFKTMRTLRALRPLRAMSKMEGMKVVVNALIGALPSIFNVLLVCIVFWLIFAIIGVNLFMGTFHKCIDSIXGHKFSHEIIPNKTVCLNQTNAQWINSKVTFDNVIMAYLALLQVATWKGWITIMDDAIDSVAINKQPYREASIGMYF--YFVAFIILGSFFTLNLLVGVIIDKFNE----------QKNKGGSSLDAFMTEDQ------------------------------KKYIAAMKKASKKKPLKALPRPYW------KPQAIVFGIVTNKK-FDMIIMGFIGLNMLTMMM-DHYQQTEGWTFVLDNLNVFFIMIFTLEMLLKIFALR-----QYYFSEPWNLFDFFIVLLSLGGLF---------LRAKGIRTLL----FSLVMALPALGNI--CLLLFLVMFIFAVFGMSLF 1452 HSP 3 Score: 82.4185 bits (202), Expect = 5.100e-16 Identity = 88/307 (28.66%), Postives = 143/307 (46.58%), Query Frame = 0
Query: 662 RFHIWKLVTSEPFENFILLLIVCNTILLMLK---FHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID-ATKMVSVGFLKLFRAARLIKLLR--RSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFF-IYAIVGMQLFGSVM---------------IDPGTT----------IDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFD 936
R +L+ +E FE +L LI+ ++ ++ L+ F P+ D L Y + + T++F +E KL + GP YF ++W DF+ V S+I+ +V + +F+ R ++ LR R++S ++ +KV L GAL +I + +L+ ++F+ I+AI+G+ LF I P T I+ F + + + L + AT + W IM DA D +AI NK +P + G Y YFV+FI L SF LNL V VI+D F+
Sbjct: 1001 RLMAMRLIENEYFEGVVLGLILLSSFVMTLEDIWFETRPV-LIDCLYYLDRILTVVFFLETTLKLFAMGPVMYFTNAWCWLDFVIVAXSLINFIASLVGAVNIPIFKTMRTLRALRPLRAMSK-------MEGMKVVVNAL-IGALPSI---------FNVLLVCIVFWLIFAIIGVNLFMGTFHKCIDSIXGHKFSHEIIPNKTVCLNQTNAQWINSKVTFDNVIMAYLALLQVATWKGWITIMDDA-----IDSVAI--NK---QPYREASIG---MYFYFVAFIILGSFFTLNLLVGVIIDKFN 1276 HSP 4 Score: 80.4925 bits (197), Expect = 1.977e-15 Identity = 61/220 (27.73%), Postives = 103/220 (46.82%), Query Frame = 0
Query: 664 HIWKLVTSEPFENF-ILLLIVCNTILLMLKFH--------GAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID--ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHN----NFRHFFQSLMLLFRCATGE 868
+ ++ +PF + I L IV N + +M + G + ++L N FT +F E KL++ PR +F D WN FDF+ V+ S+++ A + + L+ FR R+ KL + S+ ++ +L GALS + +++ ++ FI+A++GMQLFGS I+ + NF F S M++FR GE
Sbjct: 615 EVLAVIVFDPFVDLSITLCIVVNVLFMMFDHYNIEYDANGGMSMEMNNLLKNGNYFFTTIFAFESFMKLMAMSPRYFFADGWNCFDFLIVILSLVELLAXGVNGLSMLRSFRLLRVFKLAKSWKSLNDIMTIMANTL---------GALSNLT-----------VVLCIIIFIFAVMGMQLFGSFYIEKACEKWKCELPRWNFTDFLHSFMIVFRVLCGE 814 HSP 5 Score: 78.9518 bits (193), Expect = 6.415e-15 Identity = 52/203 (25.62%), Postives = 95/203 (46.80%), Query Frame = 0
Query: 291 EEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN 493
E +P +IDP A + F A+ + AE + F L+ +P+R + ++T +F+ I+ I+++ I + P + ++ FT+I+T E ++K+L GF+LH Y+RD WN++D V+ + I+ + SL+ RV R LK++ +P LK + ++ S+KN
Sbjct: 110 ELSNTPICDIDPFYADQRTFMVIAKNGSITRFSAE--------------PALFFLTPFHPIRRIAIRVLTHPLFNFIIICTILVNCIVMML--------PDTEYXSASEIIFTSIYTYESAVKLLARGFILHNFTYLRDPWNWLDFAVIGMSYITIAIDLGS------FSSLRTFRVFRALKSVAXVPGLKTIVGAIIYSVKN 284
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|322518442|sp|C9D7C2.1|CAC1A_APIME (RecName: Full=Voltage-dependent calcium channel type A subunit alpha-1; AltName: Full=Cacophony protein) HSP 1 Score: 1293.87 bits (3347), Expect = 0.000e+0 Identity = 661/1123 (58.86%), Postives = 833/1123 (74.18%), Query Frame = 0
Query: 12 SEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEA----EKERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEE------RPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIEVLRQ 1102
+EKR R++IR+ K+ ++WFVI LVF NT VAVEHY QP+WLT+FLY+AEF+FL+ F+LEM I++YALG +F+SSFNRFD +VI+GS+ EV W ++GSFGLS LRALRLLR+FKVTKYW SLRNLVI+L++++ SI+SLLFLLFLFI IFALLGMQLFGG FNF TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG G MIYSLYF++L L G+YTLLNVFLAIA D+L A L+ AE +K++Q Q E+ + + P++ +P+ EI P + Q+ EEE++++E +P+LPYSS FILS TNP+R HW+V + FD FIM++I LSSIALA+EDPV EDSPRN++L Y DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFFYC+DESK T +CQG +++ ED P +R W+ + F+YDN AMLTLFAVQT EGW +LQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF IQARPLE Y+P E + ++ IW++V S PFE FI+ LIV NT+LLM+KFH + + L Y N+ FT +FTVECI K+ +FG RN+F+D+WNTFDFITV+GSI+DA ++VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ +D T+I +HNNF+ F Q LMLLFRCATGEAWP+IML GRPCD A K G CGS++ Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D++ KV+FTTTLFALIRENL I VR +SE +QA+ ELR TI WP ++ ++LL+P + G G +TVGK+Y +LI ++W+ T+FGQIE Q
Sbjct: 553 AEKRFRYWIRKSVKSQKFYWFVIVLVFFNTVCVAVEHYGQPQWLTDFLYFAEFVFLALFMLEMFIKVYALGPRTYFDSSFNRFDCVVISGSIFEVIWSEV--KSGSFGLSVLRALRLLRIFKVTKYWKSLRNLVISLLSSMRSIISLLFLLFLFILIFALLGMQLFGGQFNFDSGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHKKG-MIYSLYFIVLVLFGNYTLLNVFLAIAVDNLANAQELSAAENEEEEEDKQKQAQEIEKEIQSLQNPKDGGAPKVEICP-------------PNGKGGKQSSEEEKKQDEDDDTGPKPMLPYSSMFILSPTNPVRRAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVWEDSPRNEVLNYFDYAFTGVFTVEMILKIIDLGIILHPGSYLREFWNIMDAVVVICAAVSFAFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCSDESKYTQQDCQGQYFVFEDGALLPEPKKREWQSQFFHYDNVMAAMLTLFAVQTGEGWPQILQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIQARPLERYMPKERNSVKYKIWRIVVSTPFEYFIMGLIVLNTVLLMMKFHRQSDAYKNTLKYMNMCFTGMFTVECILKIAAFGVRNFFKDAWNTFDFITVIGSIVDALVIEFGENFINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIALDADTSITKHNNFQSFIQGLMLLFRCATGEAWPNIMLSCVKGRPCDAKA---GKQEG------GCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPVDVDLKVNFTTTLFALIRENLNIKVRRASERNQANEELRDTIRSIWPLQAKKMLDLLIPRNEEIGRGKMTVGKIYVCLLILESWRTTRFGQIESAGQ 1630 HSP 2 Score: 117.857 bits (294), Expect = 2.645e-25 Identity = 91/316 (28.80%), Postives = 151/316 (47.78%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKF----FYCTDESKQTPDECQGYFYIVEDRERPPM---VMERN-------WEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF 621
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LGFVLH G+Y+R+ WN MD VV I+ + G L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G + D + + Q +++ P V + N WE F ++DN AMLT+F T EGW +L D++ STY W I++I ++ FF +N+ + ++ F
Sbjct: 146 TSLFILSEDNCIRKHTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPKQDKTILAQKLEATEIYFLGIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAFSQ--GIELDMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDINVIVKEGEQASPCNTDNKSEAPFGAHVCDANISTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYN------W------IYFIPLIVLGSFFMLNLVLGVLSGEF 447 HSP 3 Score: 67.781 bits (164), Expect = 4.706e-10 Identity = 67/312 (21.47%), Postives = 126/312 (40.38%), Query Frame = 0
Query: 30 FWFVIALVFLNTCTVAVEHYNQPKW----LTEFLYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF-------------------------NFPEETP-----------------------TSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEA--EKERQKQAAEQL 283
F + + L + C V + PK L + L E FL F +E +++ ALG + ++ + +N D V+ + F L LRA+R+LR K+ SL+ ++ +++ A++ +L + L+ I IFA++G++ + G+ + E P ++F+ I A+LTVFQ +T E W ++Y ++ G N +YF+ L + G + +LN+ L + + E ++ + RQ+Q +L
Sbjct: 170 FEYAVLLTIIANCVVLALEEHLPKQDKTILAQKLEATEIYFLGIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAFSQGIEL---DMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDINVIVKEGEQASPCNTDNKSEAPFGAHVCDANISTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYNW-----IYFIPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQSFLKLRRQQQLEHEL 473
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|60391851|sp|P91645.3|CAC1A_DROME (RecName: Full=Voltage-dependent calcium channel type A subunit alpha-1; AltName: Full=Protein cacophony; AltName: Full=Protein nightblind A; AltName: Full=Protein no-on-transient B; Short=Dmca1A) HSP 1 Score: 1241.87 bits (3212), Expect = 0.000e+0 Identity = 661/1124 (58.81%), Postives = 815/1124 (72.51%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEE--------EEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDATKM---------VSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGT---TIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
R+EKR RF+IR KT +++WFVI LVFLNT VAVEHY QP +LTEFLYYAEF+FL F+ EM I+MYALG +F SSFNRFD +VI+GS+ EV W + GSFGLS LRALRLLR+FKVTKYWSSLRNLVI+L+N++ SI+SLLFLLFLFI IFALLGMQLFGG FN P TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG A GMIYS+YF++L L G+YTLLNVFLAIA D+L A LT AEE + E K+ Q L E+E++ ++A + E A A + + +++EE E +P+LPYSS FILS TNP+R HW+V FD FIM++I +SSIALA+EDPV E+S RNKIL Y DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF ++G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIF+V+GVQLFNGKFFYCTDESK T ECQG ++ E+ E P R W+ + F+YDN AMLTLFAVQT EGW VLQ SM++TYE+ GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF I ARPLE Y+P + ++ +W++V S PFE FI++LIV NT+LLM+K+H + L Y N+ FT +F+VE + K++ FG +N+F+D WN FD ITV+GSI+DA M ++VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ + GT +I RHNNF+ F Q +MLLFRCATGEAWP+IML G+ CD A K GE CGS+L Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D E +V FTTTLFALIRENL I +R EMDQAD+ELR TI WP ++ + LLVP G L+VGK+Y G LI ++W+ T+FGQ++
Sbjct: 425 RAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEV--KGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIISQGG-AQKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQVEEDKEKQLQEL------------EKEMEALQADGVHVENGDGAVAPSKSKGKKKEEEKKEEEEVTEGPKPMLPYSSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAEDPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPKNRNTFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIKL--GTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDA---EKAPGE-----YCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDDELRVQFTTTLFALIRENLSIKMRAPEEMDQADMELRETITNIWPLQAKKMLNLLVPPSDQLNKGKLSVGKIYAGFLILESWRSTRFGQLD 1503 HSP 2 Score: 119.013 bits (297), Expect = 1.159e-25 Identity = 228/1111 (20.52%), Postives = 435/1111 (39.15%), Query Frame = 0
Query: 16 LRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHY---NQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSF-NRFDVM----VITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFN---------------FPEETPT---------------------------------SNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAE-EAEKERQK---------------QAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQ--------AEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALIS-FYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVL-QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALII---VTFNELGEA--------------ELQDDMDKNQKSCI-----DFAIQ----------------------ARPL----ELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPL----YFTDILSYFNLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDFITVVGSIID----------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLF-FIYAIVGMQLFGSVMI-----DPGTTID------------------------RHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFD 936
+R + R I + + + V+ + N +A+E + L + L E FL F +E +++ ALG++ +S N +++M V+TG F + L LRA+R+LR K+ SL+ ++ +++ A++ +L + L+ I IFA++G++ + G+ + ETP ++F+ I A+LTVFQ +T E W ++Y ++ G N +YFV L + G + +LN+ L + E E +K R + QA E +L +++ EE+K E AA+ ++ + + ++ + +P + F+ + R + V + F F+++++ L+++ +A E + S + L YA++ F +F E +K+ LG P Y +N D V++ ++ + + G G L L+ LR+LR K L+ + ++ S++ IFA++G+QLF G+F + TP+ N++ +A+LT+F + T E W V+ Q +S ++G I SI++IV + + +N+F+A+ + EL A EL+ +M+ Q + D A+ +P+ +++ T+ R +V F+ FI+++I ++I L + P+ IL+YF+ FT +FT+E + K+V G P +Y R+ WN D + V+ + + + ++ L++ R R +K ++R ++ + V SLK L ++ +LF FI++++G+QLF T+ + R ++ + +++ LF TGE WP ++ + + D I+ + Y+ VYF+ F F +N+FVA+I+ F
Sbjct: 27 IRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTG-----FMTQYPQIGPEVDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNW-----IYFVPLIVIGSFFMLNLVLGVLSGEFSNERNRVERRMEFQKCRFRAMFQTAMVSYLDWITQAEEVILAEERTTEEEKMHIMEARRRNAAKRKKLKSLGKSKSTDTEEEEAEEDYGDDGYLKTRSKPQGSCTGFW--RAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEH-YGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALG----PRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFG--LSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQF----NLPGGTPET---------------------------NFNTFPIALLTVFQILTGEDWNEVMYQGIISQGGAQKGMI------YSIYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQVEEDKEKQLQELEKEMEALQADGVHVENGDGAVAPSKSKGKKKEEEKKEEEEVTEGPKPMLPYSSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAE---DPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNIL---------------------IVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYI---------VYFIVF----PFFFVNIFVALIIITFQ 1044 HSP 3 Score: 116.316 bits (290), Expect = 7.187e-25 Identity = 103/385 (26.75%), Postives = 175/385 (45.45%), Query Frame = 0
Query: 329 EEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKF----FYCTDESK-------QTP-------DECQGYFYIVEDRERPPMVMERNWEKKP---FNYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF-NELGEAELQDDMDKNQ---------KSCIDFAIQARPLELYVPDETSGPRFHI 665
++EE P +S FIL+ NP+R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LG VLH +Y+R+ WN MD VV ++ Y I L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G + D +K +TP ++ G F M +E+ WE ++DN AMLT+F T EGW +L D++ S + W I+++ ++ FF +N+ + ++ F NE E + + K + S +D+ QA + L T + HI
Sbjct: 5 KKEENPPGGGPTSLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGFMTQYPQIGPEVD---LRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVC---NNTTSMCLEK-WEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFN------W------IYFVPLIVIGSFFMLNLVLGVLSGEFSNERNRVERRMEFQKCRFRAMFQTAMVSYLDWITQAEEVILAEERTTEEEKMHI 370 HSP 4 Score: 58.9214 bits (141), Expect = 2.518e-7 Identity = 78/341 (22.87%), Postives = 130/341 (38.12%), Query Frame = 0
Query: 649 PLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFH---GAPLYFTDILSYFNLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDFITVVGSIIDATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMI-------DPGTTIDRH---------------------NN------------------FRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFD 936
P L++ E + R + ++ PFE +LL I+ N ++L L+ H G L F +F VE K+++ G +Y R+ WN DF VV + T+ +G R R I++LR + L + + SL+V ++ IKA P L + +L+ I+AI+G++ + + DP + NN F + +++ +F+C T E W I+ T + L GS+ ++YFV I + SF MLNL + V+ F
Sbjct: 15 PTSLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGFM--TQYPQIGPEVDLRTLRAIRVLR-----PLKLVSGIPSLQVVLKSI-------IKAMAP--LLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILY-----------------WTNDAL-----GSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFS 317
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|5921703|sp|Q25452.1|CAC1M_MUSDO (RecName: Full=Muscle calcium channel subunit alpha-1; AltName: Full=MDL-alpha-1) HSP 1 Score: 874.774 bits (2259), Expect = 0.000e+0 Identity = 494/1153 (42.84%), Postives = 694/1153 (60.19%), Query Frame = 0
Query: 7 KRVTRSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFP--EETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDKS------------------PEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEER--PILPY-SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRE-RPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID--------------------------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGR---PCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTK 1093
K + R +R+R R+ K+ ++W +I LVFLNT +A EHY QP WL +F Y F++ F EM ++MY+LG +F S FNRFD V+ GS+ E+ + + G+S LR +RLLRVFKVTKYW SL NLV +L+N+I SI SLL LLFLFI IF LLGMQ+FGG F F EE P SNF++ +LLTVFQ+LTGEDWN VMY I + GG + G++ +Y+++L +CG+Y LLNVFLAIA D+L A +L+ E+ E E Q Q Q+ N+ + E ++ +EE E + + R + + +R +PY +SFFI S TN R+ H + F FI+ I+ SS LA+E+P+ D+ RN +L DY FTA+FT+E LK++ GFVLH GA+ R +N +D+ VV +LIS + +K L++LRVLRPL+ INR LK V CV++++K F+FAV+GVQLF GKFF C+D SK +C G + E+ + P + ER W+ F++D+ AMLTLF V T EGW +L S+ S E GPI FR ++ +YI++ I+ FF VNIFV +IVTF GE E ++ ++DKNQ++CI+FA++A+P+ Y+P + ++ +W VTS FE I +LI+ NT+ L +KF+ P Y+++IL N++FT +F++E IFKL +F +NYF D+WNTFDFI V+GS ID + ++S+ F +LFR RL+KLL + +R LL+TF++S QALPYV +L+ MLFFIYA++GMQ+FG +M++ GT+IDR+NNF+ F Q++++LFR ATGEAW +IM+ A S R CDP E V CGSS+ + YF+SF LCSF+++NLFVAVIMDNFDYLTRD SILG HHL EFI WS YDP G+I + ++ +LR I PPLG+GK CP RMA K+L+ MNMP++ +G V F TLFA++R L + ++ +D+A+ ELR TI + W T ++ +V T +TVGK Y LI D +++ K
Sbjct: 414 KYLERINRRIRRACRKAVKSQAFYWLIILLVFLNTGVLATEHYRQPIWLDQFQEYTNIFFIALFTCEMILKMYSLGFQGYFVSLFNRFDCFVVIGSISEMVLTS-SELMAPLGVSVLRCVRLLRVFKVTKYWHSLSNLVASLLNSIQSIASLLLLLFLFIVIFGLLGMQVFGGRFTFKPEEEKPRSNFDSFYQSLLTVFQILTGEDWNVVMYDGIRAYGGVFSFGIVACIYYIILFICGNYILLNVFLAIAVDNLADADSLSTIEK-EDESQIQLDNQIKNEMENEEYLQNGDHISFKAEFGADLDTYLQDEECGSYSDDENTYNKLGGVKQRVSSLPRRNTNTDMDRIKKDIPYGTSFFIFSHTNRFRIFCHRLCNHSNFGNFILCCIMFSSAMLAAENPLKADASRNIVLNKFDYFFTAVFTIELVLKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISIFFNSNAISV---VKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFSCSDGSKVYESDCHGTYLFYENGDINKPRLKEREWKNNKFHFDDVAKAMLTLFTVSTFEGWPTLLYVSIDSNKENGGPIYNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCELDKNQRNCIEFALKAKPVRRYIPKHS--IQYKVWWFVTSSSFEYSIFVLIMINTVTLAMKFYKQPEYYSEILDALNMIFTAVFSLEFIFKLAAFRFKNYFGDAWNTFDFIIVLGSFIDIVYSEIKTKEQALATCDGQSCNKAKGGSTLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSF--------------------QALPYVALLIVMLFFIYAVIGMQVFGKIMLEEGTSIDRNNNFQTFPQAVLVLFRSATGEAWQEIMM-ACSPRDDVKCDP----------ESDAVNNCGSSIAFPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVR--LPLAIKTDGNIDEANAELRATIKQIWKRTNPRLLDQVVLT---GNDDEVTVGKFYATYLIQDYFRRFK 1523 HSP 2 Score: 190.66 bits (483), Expect = 8.386e-48 Identity = 183/730 (25.07%), Postives = 320/730 (43.84%), Query Frame = 0
Query: 297 EEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALA--SEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFFYC-----TDESKQTPDE---------CQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFN-ELGEAELQDDMDK---------NQKSCIDFAIQARPLELYVPD--------------------------ETSGPRFHIW--------------------KLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSI----IDATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLC-SFIMLNLFVAVIMDN 934
++ + P + ++ A R + +++ + ER + F L+ NPLR+ IV K+F+ FI+L I + +ALA + P + + N++L +Y F IFT EC +KI+ GFVLH G+Y+R+ WNF+D +V +IS + G +K+L+ RVLRPL+ ++ +P L+ V + ++ ++ I+A++G++LF+GK T E DE C + +D P + N+DN ++MLT+F T EGW VL QD+M S++E W I+++ I+ FF +N+ + ++ F+ E +A+ + D K + + +D+ QA +E PD E + W K V S+ F I+LL+ NT +L + + P++ Y N+ F LFT E I K+ S G + YF +N FD V+GSI + ++++++ + + R RL+++ + V S L L++I Q++ + +L+ + I+ ++GMQ+FG +NF F+QSL+ +F+ TGE W +M D G Y + + +F+C ++I+LN+F+A+ +DN
Sbjct: 2 DDAVCPTETDNVQNKQKATTPKRTQRRGGKQQLDRPERAL------FCLTLKNPLRIFCIKIVDSKLFEYFILLTIFANCVALAVYTPYPSGDSNITNQMLEKIEYIFLVIFTSECVMKIIAYGFVLHTGSYLRNGWNFLDFFIVVIGMISTALSNL-VKEGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMIPLLHIALLVLFVIIIYAIIGLELFSGKLHKTCRHSNTGEYLNDLDELHACGVGFKCPSGYECFDDWVGPNDGIT--------NFDNFGLSMLTVFQCITLEGWTDVLYSIQDAMGSSWE------W------IYFVSMVILGAFFVMNLILGVLSGEFSKERTKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIE---PDPDAQIIEDCHKNKVKEVVSIDNLKDHENETQQTDSWFRSQKKYLERINRRIRRACRKAVKSQAFYWLIILLVFLNTGVLATEHYRQPIWLDQFQEYTNIFFIALFTCEMILKMYSLGFQGYFVSLFNRFDCFVVIGSISEMVLTSSELMAPLGVSVLRCVRLLRVFK------------VTKYWHSLSNLVASLLNSI-----QSIASLLLLLFLFIVIFGLLGMQVFGGRFTFKPEEEKPRSNFDSFYQSLLTVFQILTGEDWNVVMYD------------------GIRAYGGVFSFGIVACIYYIILFICGNYILLNVFLAIAVDN 666 HSP 3 Score: 127.872 bits (320), Expect = 2.068e-28 Identity = 153/698 (21.92%), Postives = 294/698 (42.12%), Query Frame = 0
Query: 16 LRFFIRRICKTSYWFWFVIALVFLNTCTVAVEH---YNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGG--------------------------SFNFPE-----------ETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAE-EAEKERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFE----RAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTN-PLRVLVHWIVTKKVFDMFIMLIIVLSSIALASE---DPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAG--TPTG-QRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN---------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQDDMDKNQKSCIDFAIQAR 648
LR F +I + + +F++ +F N +AV + L E++FL F E +++ A G + ++ + +N D ++ ++ N F + ALRA R+LR ++ SL+ ++ +++ A+ +L + L+ I I+A++G++LF G F P +NF+ ++LTVFQ +T E W V+Y+ ++ G +YFV + + G + ++N+ L + + + + +K R+KQ E+ L + + + E+I+P A++ + + E + L+ E E ++ + + L N +R V + F I+L++ L++ LA+E P+ D + Y + F A+FT E LK+ LGF Y +N D VV ++ T + P G L+ ++LLRV + K + + L A + S+ + IF ++G+Q+F G+F + P+E EK N+D+ + ++LT+F + T E W +V+ D + + G + F + I+YI+ FI + +N+F+A+ + + L +A+ ++K +S I Q +
Sbjct: 50 LRIFCIKIVDSKLFEYFILLTIFANCVALAVYTPYPSGDSNITNQMLEKIEYIFLVIFTSECVMKIIAYGFVLHTGSYLRNGWNFLDFFIVVIGMISTALSNLVKEG--FDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMIPLLHIALLVLFVIIIYAIIGLELFSGKLHKTCRHSNTGEYLNDLDELHACGVGFKCPSGYECFDDWVGPNDGITNFDNFGLSMLTVFQCITLEGWTDVLYSIQDAMGSSWEW-----IYFVSMVILGAFFVMNLILGVLSGEFSKERTKAKNRGDFQKLREKQQIEEDL---RGYLDWITQAEDIEPDPDAQIIEDCHKNKVKEVVSIDNLKDHENETQQTDSWFRSQKKY--LERINRRIRRACRKAVKSQAFYWLIILLVFLNTGVLATEHYRQPIWLDQFQE----YTNIFFIALFTCEMILKMYSLGF----QGYFVSLFNRFDCFVVIGSISEMVLTSSELMAPLGVSVLRCVRLLRVFKVTKYWHSLSNLVASLLNSIQSIASLLLLLFLFIVIFGLLGMQVFGGRFTF-------KPEE----------------------EKPRSNFDSFYQSLLTVFQILTGEDWNVVMYDGIRAY----GGVFSFGIVACIYYIILFICGNYILLNVFLAIAV---DNLADADSLSTIEKEDESQIQLDNQIK 691
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|209572767|sp|Q13698.4|CAC1S_HUMAN (RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1S; AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle; AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.1) HSP 1 Score: 871.692 bits (2251), Expect = 0.000e+0 Identity = 501/1153 (43.45%), Postives = 692/1153 (60.02%), Query Frame = 0
Query: 17 RFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPE-ETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEE--------DKSPEEEIDPIRAA------EMAFERAAEAAARAALQAEEEEEE------------------EEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDC------------VVISLKNFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVME---RNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA-----------------------------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKK 1091
R+ I K+ ++W VI +V LNT ++A EH+NQP WLT A + LS F EM ++MY LG+ +F S FNRFD V+ +LE+ V G+S LR +RLLR+FK+TKYW+SL NLV +L+N+I SI SLL LLFLFI IFALLGMQLFGG ++F + E SNF+ AL++VFQVLTGEDW +MY I + GG + GM+ +YF++L +CG+Y LLNVFLAIA D+L +A +LT A++A+ E +K+ DK+ EE ++ P+ E P A E + A ++EE+E E+ PI SSFFI S TN +RVL H IV F FI+L I+LSS ALA+EDP+ DS RN+IL + D GFT++FT+E LK+ G LH G++ R+++N +D+ VV +LIS + +K L++LRVLRPL+ INR LK V C +V +L F+FA +GVQLF GKFF CTD SK T +EC+GY+Y+ +D + PM +E R W F++DN AM++LF V T EGW +L ++ S E+ GPI RVEM+IF+I++ I+ FF +NIFV +IVTF E GE E ++ ++DKNQ+ C+ +A++ARPL Y+P ++ +W +VTS FE + LI+ NTI L ++ + I N+ FT++FT+E I KL++F R YF D WN FDF+ V+GSIID + +S F +LFR RLIKLL R+ VR LL+TF++S QALPYV +L+ MLFFIYA++GMQ+FG + + GT I+R+NNF+ F Q+++LLFRCATGEAW +I+L G+ CDP E + GE TCG++ Y YF+SF LC+F+++NLFVAVIMDNFDYLTRD SILG HHL EF W+ YDP G+I + ++ +LR I PPLG+GK CP R+A K+L+ MNMP++ +G V F TLFAL+R LKI + +QA+ ELR I K W T + ++ ++P G +TVGK Y LI ++++K
Sbjct: 422 RWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVE-SGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSTMAKKLEQKPKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISV---VKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGD--PMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPY--QYQVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSF--------------------QALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDP---ESDYAPGEEY---TCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKI--KTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPP---IGDDEVTVGKFYATFLIQEHFRK 1535 HSP 2 Score: 169.474 bits (428), Expect = 3.194e-41 Identity = 177/716 (24.72%), Postives = 307/716 (42.88%), Query Frame = 0
Query: 323 QAEEEEEEEEERPI-----LPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYA--DYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFY---------HT--IAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCV------------VISLKNFIFAVVGVQLFNGK-----FFYCTD----ESKQTPDEC----QGYFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALII-------------VTFNELGEAELQDDMDKNQKSCI---------DFAIQARPLELYVPD-----ETSG--------------PRFHIWK---LVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID-------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDA--GSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLC-SFIMLNLFVAVIMDNF 935
Q E +++ ++P+ P + F L+ NPLR IV K F+ I+L I + +ALA P+ ED + LG +Y F +F++E ++KI+ GF+ H AY+R WN +D T+V + + HT ++ G +K+L+ RVLRPL+ ++ +P L+ V + + ++ I+A++G++LF GK +F TD + P C G + E W ++DN +MLT++ T EGW VL D++ + + PW I+++ ++ FF +N+ + ++ TF +L E + D+ + S I DF L+ D E +G R WK +V S+ F ++L++ NT+ + + H PL+ T + N V LFT E + K+ G R YF +N FD V I++ A + + L+ R R+ K+ + S+ L+ + + S++ ++ + +L+ + I+A++GMQLFG D T R +NF +F Q+L+ +F+ TGE W +M + G P P L +YF+ +F+C ++I+LN+F+A+ +DN
Sbjct: 7 QDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEEPSPCARTGSGRRCTINGSE-----CRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEW------PW------IYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIR--------------------SIASLLLLLFLFIVIFALLGMQLFGG-RYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYP-------------------GMLVCIYFI-ILFVCGNYILLNVFLAIAVDNL 664 HSP 3 Score: 102.449 bits (254), Expect = 1.170e-20 Identity = 135/694 (19.45%), Postives = 276/694 (39.77%), Query Frame = 0
Query: 63 EFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVI----------TGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFN-------------FPEETPT-----------------------------SNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHW-------------IVTKKVFDMFIMLIIVLSSIALASEDPVDEDSP--RNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEP 673
E+ FL F +E +++ A G + A+ S +N D ++ +V++ + + ALRA R+LR ++ SL+ ++ ++ A+ + + L+ + I+A++G++LF G + E P+ ++F+ ++LTV+Q +T E W V+Y ++ G +YFV L L G + +LN+ L + +E EK + + ++L K + E+ + I ++ E L +E + E S + I ++ + HW IV KVF ++LI+ L+++++ASE + P ++ A+ ++FT E +K+ LG Y +N D VV ++ +G T + L+ +R+LR K L + ++ S+++ IFA++G+QLF G++ + E +++ N+DN A++++F V T E W ++ + + + G + + + I++I+ F+ + +N+F+A+ + + L EAE + QK+ + + R + +PD++ + + K + +P
Sbjct: 90 EYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEEPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPW-----IYFVTLILLGSFFILNLVLGVLSGEF--------TKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGEVMDV------EDFREGKLSLDEGGSDTE-------SLYEIAGLNKIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASE---HHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGL----RQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRS------------------------------NFDNFPQALISVFQVLTGEDWTSMMYNGIMAY----GGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAV---DNLAEAE---SLTSAQKAKAE-EKKRRKMSKGLPDKSEEEKSTMAKKLEQKP 709
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|1209676875|sp|Q02485.2|CAC1S_RAT (RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1S; AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle; AltName: Full=ROB1; AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.1) HSP 1 Score: 871.692 bits (2251), Expect = 0.000e+0 Identity = 497/1153 (43.10%), Postives = 693/1153 (60.10%), Query Frame = 0
Query: 17 RFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPE-ETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEE--------DKSPEEEIDPIRAA------EMAFERAAEAAARAALQAEEEEEE------------------EEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVME---RNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA-----------------------------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKK 1091
R+ + K+ ++W VI +V LNT ++A EH+NQP WLT A + L+ F +EM ++MY LG+ +F S FNRFD V+ +LE+ V G+S LR +RLLR+FK+TKYW+SL NLV +L+N+I SI SLL LLFLF+ IFALLGMQLFGG ++F + E SNF+ AL++VFQVLTGEDWN VMY I + GG + G++ +YF++L +CG+Y LLNVFLAIA D+L +A +LT A++A+ E +K+ DK+ EE ++ P+ E P A E + A ++EE+E E+ PI SSFFI S TN +RVL H IV F FI+L I+LSS ALA+EDP+ DS RN+IL Y DY FTA+FT+E LK+ G LH G++ R+++N +D+ VV +LIS + +K L++LRVLRPL+ INR LK V CV ++++ F+FA +GVQLF GKF+ C D SK T +EC+GY+YI +D + P +E R W F++DN AM++LF V T EGW +L ++ S E+ GP+ RVEM+IF+I++ I+ FF +NIFV +IVTF E GE E ++ ++DKNQ+ C+ +A++ARPL Y+P ++ +W +VTS FE + LI+ NTI L ++ + I N+ FT++FT+E I KL++F PR YF D WN FDF+ V+GSIID + +S F +LFR RLIKLL R+ VR LL+TF++S QALPYV +L+ MLFFIYA++GMQ+FG + + GT I+R+NNF+ F Q+++LLFRCATGEAW +I+L G+ CDP E + GE CG++ Y YF+SF LC+F+++NLFVAVIMDNFDYLTRD SILG HHL EF W+ YDP G+I + ++ +LR I PPLG+GK CP R+A K+L+ MNMP++ +G V F TLFAL+R LKI + +QA+ ELR I K W T + ++ ++P G +TVGK Y LI ++++K
Sbjct: 422 RWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVE-SGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFMIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSRGLPDKSEEERSTMTKKLEQKPKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPASPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGD--PTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPY--QYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDTLLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSF--------------------QALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKRCDP---ESDYAPGEEY---ACGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKI--KTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPP---IGDDEVTVGKFYATFLIQEHFRK 1535 HSP 2 Score: 166.392 bits (420), Expect = 3.147e-40 Identity = 174/717 (24.27%), Postives = 309/717 (43.10%), Query Frame = 0
Query: 323 QAEEEEEEEEERPI-----LPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYA--DYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCAL-------ISFYHT----IAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCV------------VISLKNFIFAVVGVQLFNGK-----FFYCTD----ESKQTPDEC----QGYFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALII-------------VTFNELGEA-ELQDDMDK-----NQKSCIDFAIQARPLELYVPDETSGP-----------------------RFHIWK---LVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID-------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDA--GSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLC-SFIMLNLFVAVIMDNF 935
Q E +++ ++P+ P + F L+ NPLR +V K F+ I+L I + +ALA P+ ED LG +Y F +F++E ++KI+ GF+ H AY+R WN +D +V + ++ T ++ G +K+L+ RVLRPL+ ++ +P L+ V + + ++ I+A++G++LF GK +F TD + P C G + E W ++DN +MLT++ + EGW VL D++ + + PW I+++ ++ FF +N+ + ++ TF +L E +L++D+ Q +D R +L + + S R WK LV S+ F ++L++ NT+ + + H PL+ T + N V LFT+E + K+ G R YF +N FD V I++ A + + L+ R RL K+ + S+ L+ + + S++ ++ + +L+ + I+A++GMQLFG D T R +NF +F Q+L+ +F+ TGE W +M + G P P V+ C +YF+ +F+C ++I+LN+F+A+ +DN
Sbjct: 7 QDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISVVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCARTGSGRPCTINGSE-----CRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEW------PW------IYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVD-DLREGKLSLDEGGSDTESLYEIEGLNKIIQFIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIR--------------------SIASLLLLLFLFMIIFALLGMQLFGG-RYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYP-------------GVLVC------IYFI-ILFVCGNYILLNVFLAIAVDNL 664 HSP 3 Score: 107.842 bits (268), Expect = 3.175e-22 Identity = 135/689 (19.59%), Postives = 278/689 (40.35%), Query Frame = 0
Query: 63 EFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVI----------TGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFN-------------FPEETPT-----------------------------SNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEE--------DKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSP--RNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEP 673
E+ FL F +E +++ A G + A+ S +N D +++ ++++ + + ALRA R+LR ++ SL+ ++ ++ A+ + + L+ + I+A++G++LF G + E P+ ++F+ ++LTV+Q ++ E W V+Y ++ G +YFV L L G + +LN+ L + +E EK + + ++L K + E+ + ++D +R +++ + E E E I+ + + R H +V KVF ++LI+ L+++++ASE + P + A+ A+FT+E +K+ LG Y +N D VV ++ +G T + L+ +R+LR K L + ++ S+++ IFA++G+QLF G++ + E +++ N+DN A++++F V T E W V+ + + + G + V + I++I+ F+ + +N+F+A+ + + L EAE + QK+ + + R + +PD++ R + K + +P
Sbjct: 90 EYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPW-----IYFVTLILLGSFFILNLVLGVLSGEF--------TKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGS-------DTESLYEIEGLNKIIQFIRHW-RQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASE---HHNQPLWLTHLQDVANRVLLALFTIEMLMKMYGLGL----RQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFMIIFALLGMQLFGGRYDFEDTEVRRS------------------------------NFDNFPQALISVFQVLTGEDWNSVMYNGIMAY----GGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAV---DNLAEAE---SLTSAQKAKAE-ERKRRKMSRGLPDKSEEERSTMTKKLEQKP 709
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|46576355|sp|O57483.1|CAC1S_LITCT (RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1S; AltName: Full=FGalpha1S; AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.1) HSP 1 Score: 869.766 bits (2246), Expect = 0.000e+0 Identity = 485/1150 (42.17%), Postives = 690/1150 (60.00%), Query Frame = 0
Query: 13 EKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPE-ETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDK--------APEEDKSPEEEI-------------------DPIRAAE----MAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPM-VMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA------------------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
+ LR R + K+ +++W VI ++ LNT +A EH++QP LT+ A + L+ F +EM +++YALG ++F S FNRFD V+ +LEV V D G+S LR +RLLR+FK+T+YW+SL NLV +L+N++ SI SLL LLFLF+ IFALLGMQ+FGG F+F + E S F+T AL+TVFQ+LTGEDW VMY I + GG GM +YF++L +CG+Y LLNVFLAIA D+L +A LT A++A+ E +K+ N DK A +E K+ E I DP +A+ E + E + +E+ P+ SSFFI S TN +RVL H I+ F FI+L I+LSSI+LA+EDP+ +S RNK+L D FT IFT E LK+ G LH G++ R+ +N +D++VV +LIS + +K L++LRVLRPL+ INR LK V C+ +++K F+F+ +GVQLF GKF+ CTD +K T DEC+GYF++ +D M + R W F++DN M++LF + T EGW +L ++ S E+ GPI +R+E+++F+IV+ I+ FF +NIFV +IVTF E GE E +D ++DKNQ+ C+ +A++ARPL Y+P ++ IW +VTS FE + LI NTI L ++ +G F+ + N+ FT +FTVE KL +F + YF D WN FDF+ V+GS+ID + +S+ F +LFR RL+KLL R VR LL+TF++S QALPYV +L+ MLFFIYA++GMQ+FG + + GT I+R++NF+ F Q+++LLFRCATGEAW +I+L G+ CDP+ + +P TCG+S Y YF+SF LC+F+++NLFVAVIMDNFDYLTRD SILG HHL EF W+ YDP G+I + ++ +LR I PPLG+GK CP R+A K+L+ MNMP++ +G V F TLF+L+R LKI + +Q++ ELR I K W T + ++ ++P G +TVGK Y LI ++++K K Q E
Sbjct: 417 HRLLRRKSRDLVKSRFFYWLVIIIILLNTVIIATEHHHQPDSLTKAQDIANEVLLALFTMEMIVKIYALGFQSYFMSLFNRFDSFVVCTGLLEVMLVA-SDIMSPLGISVLRCIRLLRIFKITRYWTSLNNLVASLLNSVRSIASLLLLLFLFMIIFALLGMQMFGGKFDFEDLEVRRSTFDTFPQALITVFQILTGEDWTAVMYNGIMAYGGPTYSGMSVCIYFIILFVCGNYILLNVFLAIAVDNLAEAENLTSAQKAKAEERKRKKLARANPDKTEEEKLLLAKKEQKAKGEGIPTTARLKIDEFESNVNEIKDPYPSADFPGDDEEEEPEIPISPRPRPLAELQLKEKAVPMPEASSFFIFSPTNKIRVLCHRIINATTFTNFILLFILLSSISLAAEDPIQPESFRNKVLSKLDIVFTVIFTTEIVLKMTAYGAFLHKGSFCRNSFNILDLSVVGVSLISMGIESSAISV---VKILRVLRVLRPLRAINRAKGLKHVVQCLFVAIKTIGNIVLVTTLLQFMFSCIGVQLFKGKFYSCTDTTKITADECRGYFFVAKDGNPAHMEAVPRVWSHSDFHFDNVLSGMMSLFTISTFEGWPQLLYRAIDSHAEDMGPIYNYRIEIAVFFIVYIILIAFFMMNIFVGFVIVTFQEQGEQEYKDCELDKNQRQCVQYALKARPLRRYIPKNPH--QYKIWYVVTSSYFEYLMFFLITLNTISLGMQHYGQTAEFSYMSDILNVAFTGIFTVEMFLKLAAFKAKGYFGDPWNVFDFLIVIGSVIDVILSEIDTPGIPATPGAEESSRISITFFRLFRVLRLVKLLSRGEGVRTLLWTFIKSF--------------------QALPYVALLIVMLFFIYAVIGMQVFGKIALVDGTHINRNSNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPM------SDFQPGEEYTCGTSFAYFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVSMNMPLNSDGTVTFNATLFSLVRTALKI--KTEGNFEQSNEELRMIIKKIWKRTSMKLLDQVIPP---IGDDEVTVGKFYAIFLIQEHFRKFKKRQEE 1529 HSP 2 Score: 176.792 bits (447), Expect = 1.447e-43 Identity = 178/690 (25.80%), Postives = 304/690 (44.06%), Query Frame = 0
Query: 341 SFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDED--SPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFY----HTIAGTP-----TGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGK-----FFYCTDES----KQTPDEC----QGYFYIVEDRERPPMVMERNWEKKPFN----YDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEA----------ELQDDMDKNQKSCIDFAIQA-------RPLELYVPDETSGPR----------------FHIWK------------LVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDATKMVS-------VGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLC-SFIMLNLFVAVIMDN 934
+ F L NP R IV K F+M I+L I + +ALA P+ ED + N +L +Y F IFT+E LKI+ GF+LH AY+R+ WN +D T+V+ + S + G P +G +K+L+ RVLRPL+ ++ +P L+ V + ++ ++ I+A+VG++LF+GK +F TD + + P C QG + E R W P N +DN AMLT++ T EGW VL D++ + + PW I+++ ++ FF +N+ + ++ F + E Q MD++ + +D+ A P + + E G F W+ LV S F ++++I+ NT+++ + H P T N V LFT+E I K+ + G ++YF +N FD V +++ + S + L+ R R+ K+ R S+ L+ + + S++ ++ + +L+ + I+A++GMQ+FG D R + F F Q+L+ +F+ TGE W +M + G P Y G S+ +YF+ +F+C ++I+LN+F+A+ +DN
Sbjct: 30 ALFCLGLQNPFRKFCINIVEWKPFEMIILLTIFANCVALAIFLPMPEDDTNSTNSVLEKVEYIFLFIFTIESFLKIVAYGFILHTDAYLRNGWNILDFTIVSVGVFSVLLEQISKLQGLPAPGKSSGFNVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMIPLLHIALLVLFMIIIYAIVGLELFSGKMHKTCYFKDTDITATVDNEKPAPCSSTGQGRQCSINGSEC------RGWWPGPNNGITHFDNFGFAMLTVYQCITMEGWTEVLYWVNDAIGNEW------PW------IYFVSLILLGSFFVLNLVLGVLSGEFTKEREKAKSRGAFQMLREQQAMDEDLRGYLDWITHAEVMDPDMEPRDGFSQLEEGGSETDSLYEIEGINKFIAFFRQWRLWHRLLRRKSRDLVKSRFFYWLVIIIILLNTVIIATEHHHQPDSLTKAQDIANEVLLALFTMEMIVKIYALGFQSYFMSLFNRFDSFVVCTGLLEVMLVASDIMSPLGISVLRCIRLLRIFKITRYWTSLNNLVASLLNSVR--------------------SIASLLLLLFLFMIIFALLGMQMFGG-KFDFEDLEVRRSTFDTFPQALITVFQILTGEDWTAVMYNG-------------IMAYGGPTY---SGMSVC-IYFI-ILFVCGNYILLNVFLAIAVDN 662 HSP 3 Score: 113.62 bits (283), Expect = 5.096e-24 Identity = 148/684 (21.64%), Postives = 281/684 (41.08%), Query Frame = 0
Query: 59 LYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHD--------RAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFN-------------FPEETPT-----------------------------SNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDK-------SPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSS--TNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWK 667
L E++FL F +E +++ A G + A+ + +N D +++ V V ++ F + ALRA R+LR ++ SL+ ++ +++ A+ +L + L+ I I+A++G++LF G + E P ++F+ A+LTV+Q +T E W +V+Y ++ G +YFV L L G + +LN+ L + + T+ E K R A Q+L + +A +ED + E +DP F + E + E + E I + +FF LR +V + F +++II+L+++ +A+E DS K A+ A+FT+E +KI LGF +Y +N D VV L+ + + + L+ +R+LR K L + ++ S+++ IFA++G+Q+F GKF + E +++ +D A++T+F + T E W V+ + + + GP + + + I++I+ F+ + +N+F+A+ + + L EAE ++ QK+ + + + L PD+T + + K
Sbjct: 86 LEKVEYIFLFIFTIESFLKIVAYGFILHTDAYLRNGWNILDFTIVSVGVFSVLLEQISKLQGLPAPGKSSGFNVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMIPLLHIALLVLFMIIIYAIVGLELFSGKMHKTCYFKDTDITATVDNEKPAPCSSTGQGRQCSINGSECRGWWPGPNNGITHFDNFGFAMLTVYQCITMEGWTEVLYWVNDAIGNEWPW-----IYFVSLILLGSFFVLNLVLGVL------SGEFTKEREKAKSR---GAFQMLREQQAMDEDLRGYLDWITHAEVMDPDMEPRDGFSQLEEGGS-------ETDSLYEIEGINKFIAFFRQWRLWHRLLRRKSRDLVKSRFFYWLVIIIILLNTVIIATEHHHQPDS-LTKAQDIANEVLLALFTMEMIVKIYALGF----QSYFMSLFNRFDSFVVCTGLLEVMLVASDIMSPLGISVLRCIRLLRIFKITRYWTSLNNLVASLLNSVRSIASLLLLLFLFMIIFALLGMQMFGGKFDFEDLEVRRS------------------------------TFDTFPQALITVFQILTGEDWTAVMYNGIMAY---GGPT-YSGMSVCIYFIILFVCGNYILLNVFLAIAV---DNLAEAE---NLTSAQKAKAE-ERKRKKLARANPDKTEEEKLLLAK 702
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|6165982|sp|Q01815.1|CAC1C_MOUSE (RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1C; AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle; AltName: Full=MELC-CC; AltName: Full=Mouse brain class C; Short=MBC; AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.2) HSP 1 Score: 863.603 bits (2230), Expect = 0.000e+0 Identity = 505/1172 (43.09%), Postives = 700/1172 (59.73%), Query Frame = 0
Query: 5 ANKRVTRSEKRLRFFIRRIC----KTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPE-ETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEE--------------AEKERQKQAAEQLLNKDKAPE-----------------------------EDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRE-RPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA---------------------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTK 1093
+ + +R +R F RR C K++ ++W VI LVFLNT T+A EHYNQP WLTE A L+ F EM ++MY+LG+ A+F S FNRFD ++ G +LE V + G+S LR +RLLR+FK+T+YW+SL NLV +L+N++ SI SLL LLFLFI IF+LLGMQLFGG FNF E +T S F+ +LLTVFQ+LTGEDWN VMY I + GG + GM+ +YF++L +CG+Y LLNVFLAIA D+L A +LT A++ A E++++ E+ ++ E EDKSP +P A E E E +E+ P+ S+FFI S N R+ H IV +F I+ I+LSSI+LA+EDPV S RN ILG ADY FT+IFTLE LK+ G LH G++ R+++N +D+ VV+ +LISF + +K L++LRVLRPL+ INR LK V CV ++++ F+FA +GVQLF GK + C+D SKQT EC+G + +D E P++ R+WE F++DN AM+ LF V T EGW +L S+ S E++GPI +RVE+SIF+I++ I+ FF +NIFV +IVTF E GE E ++ ++DKNQ+ C+++A++ARPL Y+P ++ +W +V S FE + +LI+ NTI L ++ +G F ++ N++FT LFTVE I KL++F P+ YF D WN FDF+ V+GSIID +S+ F +LFR RL+KLL R +R LL+TF++S QALPYV +L+ MLFFIYA++GMQ+FG + ++ T I+R+NNF+ F Q+++LLFRCATGEAW DIML G+ C P + N T GE CGSS YF+SF LC+F+++NLFVAVIMDNFDYLTRD SILG HHL EF W+ YDP G+I + ++ +LR I PPLG+GK CP R+A K+L+ MNMP++ +G V F TLFAL+R L+I + ++QA+ ELR I K W T + ++ +VP G +TVGK Y LI + ++K K
Sbjct: 498 SKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMS-PLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHS--NPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSF--------------------QALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGE----TPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI--KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPP---AGDDEVTVGKFYATFLIQEYFRKFK 1632 HSP 2 Score: 167.933 bits (424), Expect = 9.633e-41 Identity = 187/771 (24.25%), Postives = 321/771 (41.63%), Query Frame = 0
Query: 302 PIRAAEMAFERAAEAAARAAL------------QAEEEEEEEEERP--------ILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPR--NKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISF----------YHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFFY-CTDE-------SKQTPDECQ---GYFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFN-ELGEAELQDD---------MDKNQKSCIDFAIQA---------------RPLELYVP------------------DETSGPRF----------HIWK------------LVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA----TKMVS---VGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVM-IDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDA--GSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLC-SFIMLNLFVAVIMDNF 935
P A ++++ A +AA +A L + + + ++ +P P + L+ NP+R IV K F++ I+L I + +ALA P ED N L +Y F IFT+E LK++ G + HP AY+R+ WN +D +V L S + + G G +K+L+ RVLRPL+ ++ +P L+ V + ++ ++ I+A++G++LF GK C ++ +++ P C G+ ++ V + W+ N+DN AMLT+F T EGW VL QD+M YE +PW ++++ I FF +N+ + ++ F+ E +A+ + D ++++ K +D+ QA +P + +P E G R W+ V S F ++ L+ NT+ + + + P + T++ N LFT E + K+ S G + YF +N FD V G I++ TK++S + L+ R R+ K+ R S+ L+ + + S++ L L I +++GMQLFG D T R + F +F QSL+ +F+ TGE W +M D G P P L +YF+ +F+C ++I+LN+F+A+ +DN
Sbjct: 44 PTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNG----TVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMG--YE----LPW------VYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIF--------------------SLLGMQLFGGKFNFDEMQT--RRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP-------------------GMLVCIYFI-ILFICGNYILLNVFLAIAVDNL 756
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|32172454|sp|Q24270.2|CAC1D_DROME (RecName: Full=Voltage-dependent calcium channel type D subunit alpha-1; Short=DmCa1D) HSP 1 Score: 862.062 bits (2226), Expect = 0.000e+0 Identity = 498/1158 (43.01%), Postives = 687/1158 (59.33%), Query Frame = 0
Query: 7 KRVTRSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNF--PEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQL-------------------LNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEA-----AARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRE-RPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID------------------------------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTT-GEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTK 1093
K R +R+R R+ K+ ++W +I LVFLNT +A EHY Q WL F Y F+ F EM ++MY+LG +F S FNRFD V+ GS+ E N G+S LR +RLLRVFKVTKYW SL NLV +L+N+I SI SLL LLFLFI IFALLGMQ+FGG FNF EE NF+ ALLTVFQ++TGEDWN VMY IN+ GG ++ G + +YF++L +CG+Y LLNVFLAIA D+L A +L+E E+ E+ + A ++ + + + +EDK E + EM E AR + E + PI P +SFF+ S TN RV HW+ F I+ I+ SS LA+E+P+ + NK+L DY FTA+FT+E LK++ GFVLH GA+ R +N +D+ VV +LIS + +K L++LRVLRPL+ INR LK V CV++++K F+FAV+GVQLF GKFF CTD SK T DEC G + + +D + P + ER W F++D+ MLTLF V T EGW +L S+ S E GPI FR ++ +YI++ I+ FF VNIFV +IVTF GE E ++ D+DKNQ++CI+FA++A+P+ Y+P G ++ +W VTS FE I +LI+ NT+ L +KF+ PL++T++L N++FT +F +E +FKL +F +NYF D+WN FDFI V+GS ID + ++S+ F +LFR RL+KLL + +R LL+TF++S QALPYV +L+ +LFFIYA+VGMQ+FG + +D G I +NNF+ F Q++++LFR ATGEAW +IM+ S +P + ++N T GEP CGSS+ Y YF+SF LCSF+++NLFVAVIMDNFDYLTRD SILG HHL EFI WS YDP G+I + ++ +LR I PPLG+GK CP RMA K+L+ MNMP++ +G V F TLFA++R +L I + +D A+ ELR TI + W T + ++ +VP + +TVGK Y LI D +++ K
Sbjct: 965 KDFDRVNRRMRRACRKAVKSQAFYWLIIVLVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTN-TGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPHDESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELDDEDKMDHETLSDEEVREMCEEEEEVDEEGMITARPR-RMSEVNTATKILPIPPGTSFFLFSQTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISV---VKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKH--GIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSF--------------------QALPYVALLIVLLFFIYAVVGMQVFGKIALDGGNAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSC-SAQP--DVKCDMNSDTPGEP-----CGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSI--KTDGNIDDANSELRATIKQIWKRTNPKLLDQVVPPPGN--DDEVTVGKFYATYLIQDYFRRFK 2083 HSP 2 Score: 200.29 bits (508), Expect = 9.711e-51 Identity = 194/706 (27.48%), Postives = 316/706 (44.76%), Query Frame = 0
Query: 326 EEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALA--SEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQ------RLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMER---------NWEKKP---FNYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFN-ELGEAELQDDMDK---------NQKSCIDFAIQARPLELYVPDETSG-----------------------PRFHI----W-------------------KLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA----TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLC-SFIMLNLFVAVIMDNF 935
++ + +P P + F LS NPLR L IV K F+ I+L I + IALA + P + + N+ L +Y F IFT EC +KIL GFVLH GAY+R+ WN +D T+V IS T Q +K+L+ RVLRPL+ ++ +P L+ V + ++ ++ I+A++G++LF+GK K DE G + E+ RP V + W+ N+DN +AMLT+F T EGW VL QD+M S ++ W +++I I+ FF +N+ + ++ F+ E +A+ + D K + + +D+ QA +E PD G P + W K V S+ F I++L+ NT +L + +G + + Y N+ F LFT E + K+ S G + YF +N FD V+GSI + T M+ + + R RL+++ + + R L V SL L++I Q++ + +L+ + I+A++GMQ+FG G NF F+Q+L+ +F+ TGE W +M + +N G Y +L +YF+ +F+C ++I+LN+F+A+ +DN
Sbjct: 579 RQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAIS-------TALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLH------KACRDEITGEY---EENIRPCGVGYQCPPGYKCYGGWDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQ------W------MYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIE---PDAVGGLISDGKGKQPNEMDSTENLGEEMPEVQMTESRWRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIVLVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRS-LSNLVASL-----------LNSI-----QSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMY------------VGINAYGGVSSY-----GALACIYFI-ILFICGNYILLNVFLAIAVDNL 1218
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|116241275|sp|Q01668.2|CAC1D_HUMAN (RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1D; AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 2; AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.3) HSP 1 Score: 857.055 bits (2213), Expect = 0.000e+0 Identity = 503/1137 (44.24%), Postives = 690/1137 (60.69%), Query Frame = 0
Query: 25 KTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPE-ETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEA-----------------EKERQKQAAEQLLNKD--------KAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEE---EEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRE-RPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA-------------------------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTK 1093
K+ ++W VI LVFLNT T++ EHYNQP WLT+ A + L+ F EM ++MY+LG+ A+F S FNRFD V+ G + E V + G+S R +RLLR+FKVT++W+SL NLV +L+N++ SI SLL LLFLFI IF+LLGMQLFGG FNF E +T S F+ ALLTVFQ+LTGEDWN VMY I + GG ++ GMI +YF++L +CG+Y LLNVFLAIA D+L A +L A++ K+ K Q+ N D + +EDK P D E E E A + E +E+ PI S+FFILS TNP+RV H ++ +F I++ I+LSS ALA+EDP+ S RN ILGY DY FTAIFT+E LK+ G LH GA+ R+++N +D+ VV +L+SF + +K L++LRVLRPL+ INR LK V CV ++++ F+FA +GVQLF GKF+ CTDE+K P+EC+G F + +D + P+V ER W+ FN+DN AM+ LF V T EGW +L ++ S E GPI RVE+SIF+I++ I+ FF +NIFV +IVTF E GE E ++ ++DKNQ+ C+++A++ARPL Y+P ++ W +V S PFE + +LI+ NT+ L ++ + F D + N+VFT +FTVE + K+++F P+ YF D+WNTFD + V+GSIID + +S+ F +LFR RL+KLL R +R LL+TF++S QALPYV +L+ MLFFIYA++GMQ+FG V + I+R+NNF+ F Q+++LLFRCATGEAW +IML G+ CDP E + GE TCGS+ VYF+SF LC+F+++NLFVAVIMDNFDYLTRD SILG HHL EF WS YDP G+I + ++ +LR I PPLG+GK CP R+A K+L+ MNMP++ +G V F TLFAL+R LKI + ++QA+ ELR I K W T + ++ +VP G +TVGK Y LI D ++K K
Sbjct: 521 KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVEL-EIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPY--QYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSF--------------------QALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDP---ESDYNPGEEY---TCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKI--KTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPP---AGDDEVTVGKFYATFLIQDYFRKFK 1620 HSP 2 Score: 124.79 bits (312), Expect = 2.100e-27 Identity = 119/423 (28.13%), Postives = 192/423 (45.39%), Query Frame = 0
Query: 261 QAAALTEAEEAEKERQKQAAEQLLNKDKAPEEDK-SPEEEIDPIRAAEMAFERAAEA-------AARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPR--NKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFY-----------HTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGK-----FFYCTD-ESKQTPDECQGYFYIVEDRERPPMVME-RNWEKKP----FNYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFN-ELGEAELQDDMDK 635
QA EA A R + E ++ + ++ S + ID R A+ A + A + R Q + +++ P + F LS NP+R IV K FD+FI+L I + +ALA P ED N L +Y F IFT+E LKI+ G +LHP AY+R+ WN +D +V L S + +G G +K+L+ RVLRPL+ ++ +P L+ V + ++ ++ I+A++G++LF GK FF +D +++ P C + R+ E R+ P N+DN AMLT+F T EGW VL D+M +E +PW ++++ I FF +N+ + ++ F+ E +A+ + D K
Sbjct: 17 QADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCA---FSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMG--FE----LPW------VYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQK 424 HSP 3 Score: 70.8626 bits (172), Expect = 6.062e-11 Identity = 89/332 (26.81%), Postives = 133/332 (40.06%), Query Frame = 0
Query: 668 LVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDI------LSYFNLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDF-ITVVG--SII-----------DATKMVSVGF-LKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMI--------------DPGTTIDRHN-----------------------NFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMT--CGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNF 935
+V +PF+ FILL I N + L + P D L F ++FTVE K++++G P Y R+ WN DF I +VG S+I + + S GF +K RA R+++ LR L + V SL+V ++ IKA P L ++ +L+ + IYAI+G++LF M DP N NF +F +++ +F+C T E W D+ LY M G L +VYFVS + SF +LNL + V+ F
Sbjct: 122 IVEWKPFDIFILLAIFANCVALAIYI---PFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLR--------LVSGVPSLQVVLNSI-------IKAMVP--LLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDV------------------------LYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEF 409
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Match: gi|226693506|sp|O60840.2|CAC1F_HUMAN (RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1F; AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.4) HSP 1 Score: 857.055 bits (2213), Expect = 0.000e+0 Identity = 499/1127 (44.28%), Postives = 697/1127 (61.85%), Query Frame = 0
Query: 7 KRVTRSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPE-ETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEA-EKERQKQAAEQLLNKDKAPEEDKSPEEEI-----DPIRAAEMAFERAAEAAARAALQAEEEEE---EEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISF-YHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRE-RPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIID-----------------ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKK 1091
+R+ R+ + LR RR K++ +W V+ LVFLNT T+A EH+ QP WLT+ YA + L F +EM +++Y LG A+ +S FNRFD V+ G +LE V G+S LR +RLLR+FKVT++W+SL NLV +L+N++ SI SLL LLFLFI IF+LLGMQLFGG FNF + T S F+T ALLTVFQ+LTGEDWN VMY I + GG GM+ +YF++L +CG+Y LLNVFLAIA D+L A T ++ EK +K ++ N+ P +K EE D E E E A E +E +E+ PI S+FF LS TNPLR H ++ VF I++ I+LSS++LA+EDP+ S RN ILGY DY FT+IFT+E LK+ G LH G++ R ++N +D+ VV+ +LISF H+ A + +K L++LRVLRPL+ INR LK V CV ++++ F+FA +GVQLF GKF+ CTDE+K TP EC+G F + D + P+V ER W FN+DN AM+ LF V T EGW +L ++ + E+ GPI +RVE+S+F+IV+ I+ FF +NIFV +I+TF GE E Q+ ++DKNQ+ C+++A++A+PL Y+P ++ +W V S FE + LLI+ NT+ L ++ + F + N+VFT LFT+E + K+++F P++YF D+WNTFD + VVGSI+D + +S+ F +LFR RL+KLL + +R LL+TF++S QALPYV +L+ M+FFIYA++GMQ+FG V + GT I+R+NNF+ F Q+++LLFRCATGEAW +IML + G CDP E + GE TCGS+ YF+SF LC+F+++NLFVAVIMDNFDYLTRD SILG HHL EF WS YDP G+I + ++ +LR I PPLG+GK CP R+A K+L+ MNMP++ +G V F TLFAL+R +LKI + ++QA+ ELR I K W K++ ++ ++P +TVGK Y LI D ++K
Sbjct: 509 RRLRRANRVLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLKLYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQ-PLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGGEKSNEKDLPQE--NEGLVPGVEKEEEEGARREGADMEEEEEEEEEEEEEEEEEGAGGVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILGYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAIS----VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPH--QYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGSIVDIAVTEVNNGGHLGESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSF--------------------QALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDP---ESDFGPGEEF---TCGSNFAIAYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSLKI--KTEGNLEQANQELRIVIKKIWKRMKQKLLDEVIPPPDEE---EVTVGKFYATFLIQDYFRK 1595 HSP 2 Score: 142.51 bits (358), Expect = 7.274e-33 Identity = 220/1039 (21.17%), Postives = 395/1039 (38.02%), Query Frame = 0
Query: 59 LYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHDRAG----------SFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNF----------PEETPT-----------------------------SNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSL---YFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAE-EAEKERQKQAAEQLLNK-----DKAPE---EDKSPEEEIDPI----------RAAEMAFERAAE---------------------AAARAALQAEEEEEEEEERPILPYSSFF-----------ILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSP--RNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLK------------NFIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGP-IPWFRVEMSIFYIVFFIVFPFFFVNIFVALII--VTFNELGEAELQDDMDKNQK-----------------------------------------------SCIDFAIQARPLELYVP----------DETSGPRFHIWKLVTSEPFENFILLLIVCNTILLM----LKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGP---RNYFRDSW-NTFDFITVVGSIID-ATKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLF-------------------GSVMIDPGTTIDR-----------HNNFRHFFQSLMLLFRCATGEAWPDIMLDA 877
L E++FL F +E +++ A G++ A+ + +N D +++ + V R G F + ALRA R+LR ++ SL ++ ++M A+ +L + L+ I I+A++G++LF G + EE P+ +NF+ A+LTVFQ +T E W V+Y ++ G Y L YFV L + G + +LN+ L + + +A + +K+R+KQ E+ L +A E ED S ++ + + + AE+ R A+ ++ + +E+EEE + + + + LR V ++L++ L+++ +ASE P +I YA+ +FT+E LK+ LG P AY+ F+N D VV ++ G + L+ +R+LR K L + ++ S+K IF+++G+QLF GKF + +K++ +D A+LT+F + T E W +V+ D + + GP P V I++I+ FI + +N+F+A+ + + + G A+ + N+K ++ + P E VP +T+ R L+ F N IL+ I+ +++ L ++ H + IL YF+ FT +FTVE + K+ FG R F SW N D + V S+I ++ +K+ R R+++ L R+++ L VQ + V+ T+ + ++ +L F++A +G+QLF GS ++ P + R NF + ++M LF +T E WP ++ A
Sbjct: 127 LEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQDAMG--------YELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEEDLRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSMTETQGDEDEEEGALASCTRCLNKIMKTRVCRRLRRANRVLRARCRRAVKSNACYWAVLLLVFLNTLTIASE---HHGQPVWLTQIQEYANKVLLCLFTVEMLLKLYGLG----PSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRS------------------------------TFDTFPQALLTVFQILTGEDWNVVMYDGIMAY---GGPFFPGMLV--CIYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGGEKSNEKDLPQENEGLVPGVEKEEEEGARREGADMEEEEEEEEEEEEEEEEEGAGGVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHS---FRNHILGYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPL-RAINRAKGLKHVVQCVFVAIRTIG----------------NIMIVTTLLQFMFACIGVQLFKGKFYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKA 1095 HSP 3 Score: 135.191 bits (339), Expect = 1.306e-30 Identity = 112/367 (30.52%), Postives = 169/367 (46.05%), Query Frame = 0
Query: 341 SFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPR--NKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFY------------HTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGK-----FFYCTD-ESKQTPDECQGY-------FYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGE-----AELQDDMDKNQ-----KSCIDFAIQARPLELYVP 655
+ F L+ NPLR IV K FD+ I+L I + +AL P ED N L +Y F IFT+E LKI+ G VLHP AY+R+ WN +D +V L S HT G P G +K+L+ RVLRPL+ ++ +P L V + ++ +L I+A++G++LF G+ +F +D E+++ P C E R R P N+DN F AMLT+F T EGW VL QD+M YE +PW ++++ I FF +N+ + ++ F++ E + Q +K Q + +D+ QA L++ P
Sbjct: 71 ALFCLTLANPLRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHT-GGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRACTLNQTECRGRWP-----GPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQDAMG--YE----LPW------VYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEEDLRGYLDWITQAEELDMEDP 419 HSP 4 Score: 76.2554 bits (186), Expect = 1.193e-12 Identity = 99/376 (26.33%), Postives = 149/376 (39.63%), Query Frame = 0
Query: 624 LGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDI------LSYFNLVFTLLFTVECIFKLVSFG----PRNYFRDSWNTFDFITVV------------GSIIDA--TKMVSVGF-LKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLF-----------GSVM---IDPGTTIDRHN-----------------------NFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVM--TCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNF 935
LG + ++ K++ + A Q P L+ + R +V +PF+ ILL I N + L + P D L VF ++FTVE + K+V++G P Y R+ WN DFI VV G DA T GF +K RA R+++ LR L + V SL + ++ +KA P L ++ +L+ + IYAI+G++LF GS M DP + NF +FF +++ +F+C T E W D+ LY M G L +VYFVS + SF +LNL + V+ F
Sbjct: 45 LGTPKRRNQHSKHKTVAVASA-QRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIFANCVALGVYI---PFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLR--------LVSGVPSLHIVLNSI-------MKALVP--LLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDV------------------------LYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEF 375
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1218263695|ref|XP_021710363.1| (voltage-dependent calcium channel type A subunit alpha-1 isoform X8 [Aedes aegypti]) HSP 1 Score: 1303.89 bits (3373), Expect = 0.000e+0 Identity = 673/1116 (60.30%), Postives = 832/1116 (74.55%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAP---EEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEE---EEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
R+EKR RF+IR KT +++WFVI LVF NT VAVEHY QP WLT+FLYYAE++FL F++EM I+MYALG +F SSFNRFD +VI+GS+ EV W + GSFGLS LRALRLLR+FKVTKYWSSLRNLVI+L+N++ SI+SLLFLLFLFI IFALLGMQLFGG FN P+ TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG G MIYSLYF++L L G+YTLLNVFLAIA D+L A LT AEE + E K+ + L+K+ + D SP + + + R + A + +EE++ + +P+LPYSS F+LS TNP+R HW+V + FD FIM++I LSSIALA+EDPV+EDSPRNKIL + DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFFYCTD+SK T +EC+G F++ + ++ P R W+ + F+YDN AMLTLFAVQT EGW VLQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF I ARPLE Y+P++ + ++ +W++V S PFE FI++LIV NT+LLM+KFH AP DILS+ NLVFT F +E I KL++FG +N+F+D WN FDFITV+GSIIDA +VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ ++P + I RHNNFR F Q LMLLFRCATGE+WP+IML GRPCDP A + N+T CGS+L Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D EGKV FTTTLFALIRENL I +R + EMDQAD ELR TI WP ++ ++LLVP TG LTVGK+Y G+LI ++W+ TKFGQIE
Sbjct: 537 RAEKRFRFWIRHTVKTQWFYWFVIVLVFFNTVCVAVEHYGQPNWLTQFLYYAEYVFLGLFMMEMWIKMYALGPRIYFESSFNRFDCVVISGSIFEVVWSEV--KGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPDGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHKKG-MIYSLYFIILVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQMEENKEKQQMELDKEMGALHLQTDGSPPR----VEVSSPSPTRGNGSKANKKEEDKEEDDDDIPDGPKPMLPYSSMFVLSPTNPIRCAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVEEDSPRNKILNFFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCTDDSKHTSEECKGSFFVYDGTDQLPRREVREWKTQSFHYDNVATAMLTLFAVQTGEGWPQVLQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPNKRNSFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKFHEAPPTLIDILSFMNLVFTFFFLLETIMKLIAFGCKNFFKDPWNIFDFITVIGSIIDALVLELGENSFNVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIELEPESAITRHNNFRSFVQGLMLLFRCATGESWPNIMLACLKGRPCDPRAGKSNET---------CGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDAEGKVGFTTTLFALIRENLNIKMRTAEEMDQADQELRQTISHIWPLQAKKLLDLLVPRKDELNTGKLTVGKIYAGLLILESWRNTKFGQIE 1616 HSP 2 Score: 112.464 bits (280), Expect = 3.078e-21 Identity = 96/373 (25.74%), Postives = 167/373 (44.77%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFF---YCTDESKQT------PDECQG--------YFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF----------NELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHI 665
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LGFV+H +Y+R+ WN MD VV I+ + L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G Y ++ Q P C Y+ + M +E+ WE F ++DN AMLT+F T EGW +L D++ ST+ W I+++ ++ FF +N+ + ++ F E + Q ++K +++ +A + L T + HI
Sbjct: 120 TSLFILSEDNIIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPHGDKTLLAQKLEKTEAYFLGIFCVEASLKILALGFVMHKHSYLRNIWNIMDFFVVVTGFITLFPQEGPEVD---LRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHRSCYSLEDISQIVKEGEFPTPCNADNDTIAPTGAYVCNSSDS--MCVEQ-WEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTFN------W------IYFVPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQEFLKLRRQQQLEKELNGYVEWICKAEEVILAEERTTEEEKMHI 474
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1218263707|ref|XP_021710370.1| (voltage-dependent calcium channel type A subunit alpha-1 isoform X14 [Aedes aegypti]) HSP 1 Score: 1303.89 bits (3373), Expect = 0.000e+0 Identity = 673/1116 (60.30%), Postives = 833/1116 (74.64%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAP---EEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEE---EEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDATKM------VSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
R+EKR RF+IR KT +++WFVI LVF NT VAVEHY QP WLT+FLYYAE++FL F++EM I+MYALG +F SSFNRFD +VI+GS+ EV W + GSFGLS LRALRLLR+FKVTKYWSSLRNLVI+L+N++ SI+SLLFLLFLFI IFALLGMQLFGG FN P+ TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG G MIYSLYF++L L G+YTLLNVFLAIA D+L A LT AEE + E K+ + L+K+ + D SP + + + R + A + +EE++ + +P+LPYSS F+LS TNP+R HW+V + FD FIM++I LSSIALA+EDPV+EDSPRNKIL + DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFFYCTD+SK T +EC+G F++ + ++ P R W+ + F+YDN AMLTLFAVQT EGW VLQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF I ARPLE Y+P++ + ++ +W++V S PFE FI++LIV NT+LLM+KFH AP DILS+ NLVFT F +E I KL++FG +N+F+D WN FDFITV+GSIIDA + +VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ ++P + I RHNNFR F Q LMLLFRCATGE+WP+IML GRPCDP A + N+T CGS+L Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D EGKV FTTTLFALIRENL I +R + EMDQAD ELR TI WP ++ ++LLVP TG LTVGK+Y G+LI ++W+ TKFGQIE
Sbjct: 537 RAEKRFRFWIRHTVKTQWFYWFVIVLVFFNTVCVAVEHYGQPNWLTQFLYYAEYVFLGLFMMEMWIKMYALGPRIYFESSFNRFDCVVISGSIFEVVWSEV--KGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPDGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHKKG-MIYSLYFIILVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQMEENKEKQQMELDKEMGALHLQTDGSPPR----VEVSSPSPTRGNGSKANKKEEDKEEDDDDIPDGPKPMLPYSSMFVLSPTNPIRCAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVEEDSPRNKILNFFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCTDDSKHTSEECKGSFFVYDGTDQLPRREVREWKTQSFHYDNVATAMLTLFAVQTGEGWPQVLQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPNKRNSFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKFHEAPPTLIDILSFMNLVFTFFFLLETIMKLIAFGCKNFFKDPWNIFDFITVIGSIIDALVLELGENSFNVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIELEPESAITRHNNFRSFVQGLMLLFRCATGESWPNIMLACLKGRPCDPRAGKSNET---------CGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDAEGKVGFTTTLFALIRENLNIKMRTAEEMDQADQELRQTISHIWPLQAKKLLDLLVPRKDELNTGKLTVGKIYAGLLILESWRNTKFGQIE 1616 HSP 2 Score: 112.849 bits (281), Expect = 2.596e-21 Identity = 97/373 (26.01%), Postives = 168/373 (45.04%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFF---YCTDESKQT------PDECQG--------YFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF----------NELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHI 665
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LGFV+H +Y+R+ WN MD VV I+ + G L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G Y ++ Q P C Y+ + M +E+ WE F ++DN AMLT+F T EGW +L D++ ST+ W I+++ ++ FF +N+ + ++ F E + Q ++K +++ +A + L T + HI
Sbjct: 120 TSLFILSEDNIIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPHGDKTLLAQKLEKTEAYFLGIFCVEASLKILALGFVMHKHSYLRNIWNIMDFFVVVTGFITLFPQ-EGPEVD--LRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHRSCYSLEDISQIVKEGEFPTPCNADNDTIAPTGAYVCNSSDS--MCVEQ-WEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTFN------W------IYFVPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQEFLKLRRQQQLEKELNGYVEWICKAEEVILAEERTTEEEKMHI 474
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1218263709|ref|XP_021710371.1| (voltage-dependent calcium channel type A subunit alpha-1 isoform X15 [Aedes aegypti]) HSP 1 Score: 1303.89 bits (3373), Expect = 0.000e+0 Identity = 673/1116 (60.30%), Postives = 833/1116 (74.64%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAP---EEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEE---EEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDATKM------VSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
R+EKR RF+IR KT +++WFVI LVF NT VAVEHY QP WLT+FLYYAE++FL F++EM I+MYALG +F SSFNRFD +VI+GS+ EV W + GSFGLS LRALRLLR+FKVTKYWSSLRNLVI+L+N++ SI+SLLFLLFLFI IFALLGMQLFGG FN P+ TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG G MIYSLYF++L L G+YTLLNVFLAIA D+L A LT AEE + E K+ + L+K+ + D SP + + + R + A + +EE++ + +P+LPYSS F+LS TNP+R HW+V + FD FIM++I LSSIALA+EDPV+EDSPRNKIL + DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFFYCTD+SK T +EC+G F++ + ++ P R W+ + F+YDN AMLTLFAVQT EGW VLQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF I ARPLE Y+P++ + ++ +W++V S PFE FI++LIV NT+LLM+KFH AP DILS+ NLVFT F +E I KL++FG +N+F+D WN FDFITV+GSIIDA + +VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ ++P + I RHNNFR F Q LMLLFRCATGE+WP+IML GRPCDP A + N+T CGS+L Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D EGKV FTTTLFALIRENL I +R + EMDQAD ELR TI WP ++ ++LLVP TG LTVGK+Y G+LI ++W+ TKFGQIE
Sbjct: 537 RAEKRFRFWIRHTVKTQWFYWFVIVLVFFNTVCVAVEHYGQPNWLTQFLYYAEYVFLGLFMMEMWIKMYALGPRIYFESSFNRFDCVVISGSIFEVVWSEV--KGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPDGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHKKG-MIYSLYFIILVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQMEENKEKQQMELDKEMGALHLQTDGSPPR----VEVSSPSPTRGNGSKANKKEEDKEEDDDDIPDGPKPMLPYSSMFVLSPTNPIRCAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVEEDSPRNKILNFFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCTDDSKHTSEECKGSFFVYDGTDQLPRREVREWKTQSFHYDNVATAMLTLFAVQTGEGWPQVLQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPNKRNSFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKFHEAPPTLIDILSFMNLVFTFFFLLETIMKLIAFGCKNFFKDPWNIFDFITVIGSIIDALVLELGENSFNVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIELEPESAITRHNNFRSFVQGLMLLFRCATGESWPNIMLACLKGRPCDPRAGKSNET---------CGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDAEGKVGFTTTLFALIRENLNIKMRTAEEMDQADQELRQTISHIWPLQAKKLLDLLVPRKDELNTGKLTVGKIYAGLLILESWRNTKFGQIE 1616 HSP 2 Score: 112.849 bits (281), Expect = 2.587e-21 Identity = 97/373 (26.01%), Postives = 168/373 (45.04%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFF---YCTDESKQT------PDECQG--------YFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF----------NELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHI 665
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LGFV+H +Y+R+ WN MD VV I+ + G L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G Y ++ Q P C Y+ + M +E+ WE F ++DN AMLT+F T EGW +L D++ ST+ W I+++ ++ FF +N+ + ++ F E + Q ++K +++ +A + L T + HI
Sbjct: 120 TSLFILSEDNIIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPHGDKTLLAQKLEKTEAYFLGIFCVEASLKILALGFVMHKHSYLRNIWNIMDFFVVVTGFITLFPQ-EGPEVD--LRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHRSCYSLEDISQIVKEGEFPTPCNADNDTIAPTGAYVCNSSDS--MCVEQ-WEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTFN------W------IYFVPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQEFLKLRRQQQLEKELNGYVEWICKAEEVILAEERTTEEEKMHI 474
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1061101318|ref|XP_017877478.1| (PREDICTED: voltage-dependent calcium channel type A subunit alpha-1 isoform X4 [Ceratina calcarata]) HSP 1 Score: 1303.89 bits (3373), Expect = 0.000e+0 Identity = 662/1113 (59.48%), Postives = 827/1113 (74.30%), Query Frame = 0
Query: 12 SEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKD----KAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
+EKR R++IR+ K+ ++WFVI LVF NT VAVEHYNQP+WLT+FLYYAEF+FL+ F+LEM I++YALG +F+SSFNRFD +VI+GS+ EV W ++GSFGLS LRALRLLR+FKVTKYW SLRNLVI+L++++ SI+SLLFLLFLFI IFALLGMQLFGG FNF TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG GM+YSLYF++L L G+YTLLNVFLAIA D+L A L+ AE E+ KQ Q L K+ + P++ +P+ EI P + + E + + ++E+++ +P+LPYSS FILS TNP+R HW+V + FD+FIM++I LSSIALA+EDPV E+SPRNK+L Y DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFF+CTDESK T +ECQG +++ ED P +R W + F+YDN AMLTLFAVQT EGW +LQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF IQARPLE Y+P + +F IW +V S PFE FI+ LIV NT+LLM+KFH + + L Y N+ FT LFTVECI K+ +FG RN+F+D+WN FDFITV+GSI+DA ++VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ +D T+I +HNNF+ F Q LMLLFRCATGEAWP+IML RPCDP A +K G CGS++ Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ WS YDP+ TGKIHY E+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D KV+FTTTLFALIRENL I VR ++E QA+ ELR TI WP R+ ++LL+P + G G +TVGK+Y +LI ++W+ TKFGQIE
Sbjct: 430 AEKRFRYWIRKSVKSQNFYWFVIILVFFNTVCVAVEHYNQPEWLTDFLYYAEFVFLALFMLEMFIKVYALGPRTYFDSSFNRFDCVVISGSIFEVIWSAL--KSGSFGLSVLRALRLLRIFKVTKYWKSLRNLVISLLSSMRSIISLLFLLFLFILIFALLGMQLFGGQFNFEAGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGG-TKRGMVYSLYFIVLVLFGNYTLLNVFLAIAVDNLANAQELSAAENMEENEDKQKQAQELEKEIQTLQKPKDGNAPKVEICPPSPNQNFKDGKGEKQSSEEEKKQDEDDDTGPKPMLPYSSMFILSPTNPIRRAAHWVVNLRYFDVFIMVVITLSSIALAAEDPVWEESPRNKVLNYFDYAFTGVFTVEMLLKIVDLGIILHPGSYLREFWNIMDAVVVICAAVSFAFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFFCTDESKYTKEECQGQYFVFEDNGMLPEPRKREWSTQSFHYDNVMAAMLTLFAVQTGEGWPQILQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIQARPLERYMPRDRKSVKFRIWSIVVSTPFEYFIMCLIVLNTLLLMMKFHRQSDVYKNTLKYMNMCFTGLFTVECILKIAAFGVRNFFKDAWNIFDFITVIGSIVDALVIEFGENFINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIALDAETSITKHNNFQSFLQGLMLLFRCATGEAWPNIMLSCVKDRPCDPKA---SKQQG------GCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWSEYDPNATGKIHYKEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPVDENLKVNFTTTLFALIRENLNIKVRSANERHQANEELRDTIRSIWPLQARKILDLLIPRNEELGRGKMTVGKIYVCLLILESWRSTKFGQIE 1510 HSP 2 Score: 120.168 bits (300), Expect = 1.498e-23 Identity = 93/316 (29.43%), Postives = 152/316 (48.10%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKF----FYCTDESKQTPDECQGYFYIVEDRERPPM---VMERN-------WEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF 621
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F AIF +E SLKIL LGFVLH G+Y+R+ WN MD VV I+ + G L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G + D S + Q +++ P V + N WE F ++DN AMLT+F T EGW +L D++ STY W I++I ++ FF +N+ + ++ F
Sbjct: 22 TSLFILSEDNCIRKHTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLAIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAFSQ--GIELDMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDISVIVKEGEQASPCNTDNKSEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYN------W------IYFIPLIVLGSFFMLNLVLGVLSGEF 323 HSP 3 Score: 105.531 bits (262), Expect = 5.129e-19 Identity = 68/264 (25.76%), Postives = 132/264 (50.00%), Query Frame = 0
Query: 7 KRVTRSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPT--SNFNTIVAALLTVFQVLTGEDWNQVMYTAI-----NSKGGRANGGM---IYSLYFVMLTLCGDYTLLNVFLAIACDSLD 260
+ + R K ++F I I ++ + +F++ L+ LNT + ++ + Q L Y F F +E +++ A GV FF ++N FD + + GS+++ + F + + G LR R R+ K+ + ++R L+ + + ++ + L+ + FI+A++GMQ+FG E + T +NF + + L+ +F+ TGE W +M + + + K + GG I YFV + +LN+F+A+ D+ D
Sbjct: 1087 RYMPRDRKSVKFRIWSIVVSTPFEYFIMCLIVLNTLLLMMKFHRQSDVYKNTLKYMNMCFTGLFTVECILKIAAFGVRNFFKDAWNIFDFITVIGSIVDALVIEFGENFINVGF--LRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDAETSITKHNNFQSFLQGLMLLFRCATGEAWPNIMLSCVKDRPCDPKASKQQGGCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFD 1348 HSP 4 Score: 68.1662 bits (165), Expect = 1.026e-7 Identity = 67/312 (21.47%), Postives = 127/312 (40.71%), Query Frame = 0
Query: 30 FWFVIALVFLNTCTVAVEHYNQPKW----LTEFLYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF-------------------------NFPEETP-----------------------TSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEA--EKERQKQAAEQL 283
F + + L + C V + PK L + L E FL+ F +E +++ ALG + ++ + +N D V+ + F L LRA+R+LR K+ SL+ ++ +++ A++ +L + L+ I IFA++G++ + G+ + E P ++F+ I A+LTVFQ +T E W ++Y ++ G N +YF+ L + G + +LN+ L + + E ++ + RQ+Q +L
Sbjct: 46 FEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLAIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAFSQGIE---LDMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDISVIVKEGEQASPCNTDNKSEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYNW-----IYFIPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQSFLKLRRQQQLEHEL 349
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1218263687|ref|XP_021710360.1| (voltage-dependent calcium channel type A subunit alpha-1 isoform X4 [Aedes aegypti]) HSP 1 Score: 1303.12 bits (3371), Expect = 0.000e+0 Identity = 673/1116 (60.30%), Postives = 832/1116 (74.55%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAP---EEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEE---EEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
R+EKR RF+IR KT +++WFVI LVF NT VAVEHY QP WLT+FLYYAE++FL F++EM I+MYALG +F SSFNRFD +VI+GS+ EV W + GSFGLS LRALRLLR+FKVTKYWSSLRNLVI+L+N++ SI+SLLFLLFLFI IFALLGMQLFGG FN P+ TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG G MIYSLYF++L L G+YTLLNVFLAIA D+L A LT AEE + E K+ + L+K+ + D SP + + + R + A + +EE++ + +P+LPYSS F+LS TNP+R HW+V + FD FIM++I LSSIALA+EDPV+EDSPRNKIL + DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFFYCTD+SK T +EC+G F++ + ++ P R W+ + F+YDN AMLTLFAVQT EGW VLQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF I ARPLE Y+P++ + ++ +W++V S PFE FI++LIV NT+LLM+KFH AP DILS+ NLVFT F +E I KL++FG +N+F+D WN FDFITV+GSIIDA +VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ ++P + I RHNNFR F Q LMLLFRCATGE+WP+IML GRPCDP A + N+T CGS+L Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D EGKV FTTTLFALIRENL I +R + EMDQAD ELR TI WP ++ ++LLVP TG LTVGK+Y G+LI ++W+ TKFGQIE
Sbjct: 537 RAEKRFRFWIRHTVKTQWFYWFVIVLVFFNTVCVAVEHYGQPNWLTQFLYYAEYVFLGLFMMEMWIKMYALGPRIYFESSFNRFDCVVISGSIFEVVWSEV--KGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPDGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHKKG-MIYSLYFIILVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQMEENKEKQQMELDKEMGALHLQTDGSPPR----VEVSSPSPTRGNGSKANKKEEDKEEDDDDIPDGPKPMLPYSSMFVLSPTNPIRCAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVEEDSPRNKILNFFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCTDDSKHTSEECKGSFFVYDGTDQLPRREVREWKTQSFHYDNVATAMLTLFAVQTGEGWPQVLQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPNKRNSFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKFHEAPPTLIDILSFMNLVFTFFFLLETIMKLIAFGCKNFFKDPWNIFDFITVIGSIIDALVLELGENSFNVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIELEPESAITRHNNFRSFVQGLMLLFRCATGESWPNIMLACLKGRPCDPRAGKSNET---------CGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDAEGKVGFTTTLFALIRENLNIKMRTAEEMDQADQELRQTISHIWPLQAKKLLDLLVPRKDELNTGKLTVGKIYAGLLILESWRNTKFGQIE 1616 HSP 2 Score: 113.235 bits (282), Expect = 2.018e-21 Identity = 97/373 (26.01%), Postives = 167/373 (44.77%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFF---YCTDESKQT------PDECQG--------YFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF----------NELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHI 665
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LGFV+H +Y+R+ WN MD VV ++ + A L+ L+ RVLRPLK ++RIP L+ V ++ ++ IFA++G++ ++G Y ++ Q P C Y+ + M +E+ WE F ++DN AMLT+F T EGW +L D++ ST+ W I+++ ++ FF +N+ + ++ F E + Q ++K +++ +A + L T + HI
Sbjct: 120 TSLFILSEDNIIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPHGDKTLLAQKLEKTEAYFLGIFCVEASLKILALGFVMHKHSYLRNIWNIMDFFVVVTGSMTIF---AEANVDVDLRMLRSFRVLRPLKLVSRIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHRSCYSLEDISQIVKEGEFPTPCNADNDTIAPTGAYVCNSSDS--MCVEQ-WEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTFN------W------IYFVPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQEFLKLRRQQQLEKELNGYVEWICKAEEVILAEERTTEEEKMHI 474
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1061101314|ref|XP_017877476.1| (PREDICTED: voltage-dependent calcium channel type A subunit alpha-1 isoform X2 [Ceratina calcarata]) HSP 1 Score: 1303.12 bits (3371), Expect = 0.000e+0 Identity = 665/1129 (58.90%), Postives = 827/1129 (73.25%), Query Frame = 0
Query: 12 SEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKD----KAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA----------------------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
+EKR R++IR+ K+ ++WFVI LVF NT VAVEHYNQP+WLT+FLYYAEF+FL+ F+LEM I++YALG +F+SSFNRFD +VI+GS+ EV W ++GSFGLS LRALRLLR+FKVTKYW SLRNLVI+L++++ SI+SLLFLLFLFI IFALLGMQLFGG FNF TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG GM+YSLYF++L L G+YTLLNVFLAIA D+L A L+ AE E+ KQ Q L K+ + P++ +P+ EI P + + E + + ++E+++ +P+LPYSS FILS TNP+R HW+V + FD+FIM++I LSSIALA+EDPV E+SPRNK+L Y DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFF+CTDESK T +ECQG +++ ED P +R W + F+YDN AMLTLFAVQT EGW +LQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF IQARPLE Y+P + +F IW +V S PFE FI+ LIV NT+LLM+KFH + + L Y N+ FT LFTVECI K+ +FG RN+F+D+WN FDFITV+GSI+DA ++VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ DPGT ID HNNF+ FF LMLLFRCATGEAWP+IML RPCDP A +K G CGS++ Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ WS YDP+ TGKIHY E+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D KV+FTTTLFALIRENL I VR ++E QA+ ELR TI WP R+ ++LL+P + G G +TVGK+Y +LI ++W+ TKFGQIE
Sbjct: 430 AEKRFRYWIRKSVKSQNFYWFVIILVFFNTVCVAVEHYNQPEWLTDFLYYAEFVFLALFMLEMFIKVYALGPRTYFDSSFNRFDCVVISGSIFEVIWSAL--KSGSFGLSVLRALRLLRIFKVTKYWKSLRNLVISLLSSMRSIISLLFLLFLFILIFALLGMQLFGGQFNFEAGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGG-TKRGMVYSLYFIVLVLFGNYTLLNVFLAIAVDNLANAQELSAAENMEENEDKQKQAQELEKEIQTLQKPKDGNAPKVEICPPSPNQNFKDGKGEKQSSEEEKKQDEDDDTGPKPMLPYSSMFILSPTNPIRRAAHWVVNLRYFDVFIMVVITLSSIALAAEDPVWEESPRNKVLNYFDYAFTGVFTVEMLLKIVDLGIILHPGSYLREFWNIMDAVVVICAAVSFAFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFFCTDESKYTKEECQGQYFVFEDNGMLPEPRKREWSTQSFHYDNVMAAMLTLFAVQTGEGWPQILQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIQARPLERYMPRDRKSVKFRIWSIVVSTPFEYFIMCLIVLNTLLLMMKFHRQSDVYKNTLKYMNMCFTGLFTVECILKIAAFGVRNFFKDAWNIFDFITVIGSIVDALVIEFGERLSGMPSGGQLGEKKENFINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNITNDPGTAIDEHNNFQSFFAGLMLLFRCATGEAWPNIMLSCVKDRPCDPKA---SKQQG------GCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWSEYDPNATGKIHYKEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPVDENLKVNFTTTLFALIRENLNIKVRSANERHQANEELRDTIRSIWPLQARKILDLLIPRNEELGRGKMTVGKIYVCLLILESWRSTKFGQIE 1526 HSP 2 Score: 119.783 bits (299), Expect = 1.736e-23 Identity = 93/316 (29.43%), Postives = 152/316 (48.10%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKF----FYCTDESKQTPDECQGYFYIVEDRERPPM---VMERN-------WEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF 621
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F AIF +E SLKIL LGFVLH G+Y+R+ WN MD VV I+ + G L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G + D S + Q +++ P V + N WE F ++DN AMLT+F T EGW +L D++ STY W I++I ++ FF +N+ + ++ F
Sbjct: 22 TSLFILSEDNCIRKHTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLAIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAFSQ--GIELDMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDISVIVKEGEQASPCNTDNKSEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYN------W------IYFIPLIVLGSFFMLNLVLGVLSGEF 323 HSP 3 Score: 107.457 bits (267), Expect = 1.027e-19 Identity = 71/278 (25.54%), Postives = 133/278 (47.84%), Query Frame = 0
Query: 7 KRVTRSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDR------AGSFG--------LSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEET--PTSNFNTIVAALLTVFQVLTGEDWNQVMYTAI-----NSKGGRANGGM---IYSLYFVMLTLCGDYTLLNVFLAIACDSLD 260
+ + R K ++F I I ++ + +F++ L+ LNT + ++ + Q L Y F F +E +++ A GV FF ++N FD + + GS+++ + F +R G G + LR R R+ K+ + ++R L+ + + ++ + L+ + FI+A++GMQ+FG N P +NF + A L+ +F+ TGE W +M + + + K + GG I YFV + +LN+F+A+ D+ D
Sbjct: 1087 RYMPRDRKSVKFRIWSIVVSTPFEYFIMCLIVLNTLLLMMKFHRQSDVYKNTLKYMNMCFTGLFTVECILKIAAFGVRNFFKDAWNIFDFITVIGSIVDALVIEFGERLSGMPSGGQLGEKKENFINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNITNDPGTAIDEHNNFQSFFAGLMLLFRCATGEAWPNIMLSCVKDRPCDPKASKQQGGCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFD 1364 HSP 4 Score: 68.5514 bits (166), Expect = 1.010e-7 Identity = 67/312 (21.47%), Postives = 127/312 (40.71%), Query Frame = 0
Query: 30 FWFVIALVFLNTCTVAVEHYNQPKW----LTEFLYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF-------------------------NFPEETP-----------------------TSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEA--EKERQKQAAEQL 283
F + + L + C V + PK L + L E FL+ F +E +++ ALG + ++ + +N D V+ + F L LRA+R+LR K+ SL+ ++ +++ A++ +L + L+ I IFA++G++ + G+ + E P ++F+ I A+LTVFQ +T E W ++Y ++ G N +YF+ L + G + +LN+ L + + E ++ + RQ+Q +L
Sbjct: 46 FEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLAIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAFSQGIE---LDMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDISVIVKEGEQASPCNTDNKSEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYNW-----IYFIPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQSFLKLRRQQQLEHEL 349
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1016161075|gb|KZC08237.1| (Voltage-dependent calcium channel type A subunit alpha-1 [Dufourea novaeangliae]) HSP 1 Score: 1303.12 bits (3371), Expect = 0.000e+0 Identity = 658/1118 (58.86%), Postives = 833/1118 (74.51%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAE----KERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIEVLRQ 1102
R+E R RF+IR+ K+ ++WFVI LVF NT VAVEHY QP+WLT+FLY+AEF+FL+ F++EM I++YALG +F+SSFNRFD +VI+GS+ EV W ++GSFGLS LRALRLLR+FKVTKYW SLRNLVI+L+N++ SI+SLLFLLFLFI IFALLGMQLFGG FNF TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG G M+YSLYF++L L G+YTLLNVFLAIA D+L A L+ AE+ + KE+Q Q E+ + + P++ +P+ EI P + F+ + + ++EE++ +P+LPYSS FILS TNP+R HW+V + FD FIM++I LSSIALA+EDPV EDSPRN++L Y DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFFYCTDESK T +CQG +++ E+ P +R W + F+YDN AMLTLFAVQT EGW +LQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF IQARPLE Y+P E + ++ IW++V S PFE FI+ LIV NT+LLM+KFH + + L Y N+ FT +FTVECI K+ +FG RN+F+D+WNTFDFITV+GSI+DA ++VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ +DP ++I +HNNF+ F Q LMLLFRCATGEAWP+IML GRPCD + EP CGS++ Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D++GKV+FTTTLFALIRENL I +R ++EM QA+ ELR I WP ++ ++LL+P + G LTVGK+Y +LI ++W+ T+FGQIE Q
Sbjct: 814 RAEMRFRFWIRKSVKSQKFYWFVIVLVFFNTVCVAVEHYGQPQWLTDFLYFAEFVFLALFMMEMFIKVYALGPRTYFDSSFNRFDCVVISGSIFEVIWSAL--KSGSFGLSVLRALRLLRIFKVTKYWKSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNFDYGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHRRG-MVYSLYFIVLVLFGNYTLLNVFLAIAVDNLANAQELSAAEDEQQVEDKEKQAQELEKEIESLQKPKDGNAPKVEICP-PSPNQNFKDGKGGKQSSEEKKQDEEDDTGPKPMLPYSSMFILSPTNPIRRAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVWEDSPRNEVLNYFDYAFTGVFTVEMILKIIDLGIILHPGSYLREFWNIMDAVVVICAAVSFAFNMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCTDESKYTEQDCQGQYFVFEEGAMLPEPKKREWHTQCFHYDNVMAAMLTLFAVQTGEGWPQILQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIQARPLERYMPKERNSVKYKIWRIVVSTPFEYFIMGLIVLNTLLLMMKFHRQSDAYKNTLKYMNMCFTGMFTVECILKIAAFGVRNFFKDAWNTFDFITVIGSIVDALVIEFGENFINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIALDPESSITKHNNFQSFIQGLMLLFRCATGEAWPNIMLSCIKGRPCD-----VKAGKQEP---GGCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPVDVDGKVNFTTTLFALIRENLSIKMRRANEMKQANEELRDAIRSIWPLQAKKMLDLLIPRSEELGRDKLTVGKIYVCLLILESWRTTRFGQIESTGQ 1899 HSP 2 Score: 112.079 bits (279), Expect = 5.081e-21 Identity = 88/327 (26.91%), Postives = 148/327 (45.26%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPF------------------------NYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMS-------IFYIVFFIVFPFFFVNIFVALIIVTF 621
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LGFVLH G+Y+R+ WN MD VV ++ + A T L+ L+ RVLRPLK +++IP L+ V ++ ++ IFA++G++ ++G +T + +I++D E+P N + PF ++DN AMLT+F T EGW +L W + E+ I++I ++ FF +N+ + ++ F
Sbjct: 399 TSLFILSEDNCIRKHTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLGIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGSMTVF---AETNVDVDLRMLRSFRVLRPLKLVSKIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTL-------HKTCYSIRDINFIMKDGEQPSPCNTDNKIEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILY--------------WVKQEICPSVTYNWIYFIPLIVLGSFFMLNLVLGVLSGEF 701
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1218263681|ref|XP_021710357.1| (voltage-dependent calcium channel type A subunit alpha-1 isoform X1 [Aedes aegypti]) HSP 1 Score: 1302.73 bits (3370), Expect = 0.000e+0 Identity = 673/1116 (60.30%), Postives = 832/1116 (74.55%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKDKAP---EEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEE---EEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
R+EKR RF+IR KT +++WFVI LVF NT VAVEHY QP WLT+FLYYAE++FL F++EM I+MYALG +F SSFNRFD +VI+GS+ EV W + GSFGLS LRALRLLR+FKVTKYWSSLRNLVI+L+N++ SI+SLLFLLFLFI IFALLGMQLFGG FN P+ TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG G MIYSLYF++L L G+YTLLNVFLAIA D+L A LT AEE + E K+ + L+K+ + D SP + + + R + A + +EE++ + +P+LPYSS F+LS TNP+R HW+V + FD FIM++I LSSIALA+EDPV+EDSPRNKIL + DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFFYCTD+SK T +EC+G F++ + ++ P R W+ + F+YDN AMLTLFAVQT EGW VLQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF I ARPLE Y+P++ + ++ +W++V S PFE FI++LIV NT+LLM+KFH AP DILS+ NLVFT F +E I KL++FG +N+F+D WN FDFITV+GSIIDA +VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ ++P + I RHNNFR F Q LMLLFRCATGE+WP+IML GRPCDP A + N+T CGS+L Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D EGKV FTTTLFALIRENL I +R + EMDQAD ELR TI WP ++ ++LLVP TG LTVGK+Y G+LI ++W+ TKFGQIE
Sbjct: 537 RAEKRFRFWIRHTVKTQWFYWFVIVLVFFNTVCVAVEHYGQPNWLTQFLYYAEYVFLGLFMMEMWIKMYALGPRIYFESSFNRFDCVVISGSIFEVVWSEV--KGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPDGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHKKG-MIYSLYFIILVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQMEENKEKQQMELDKEMGALHLQTDGSPPR----VEVSSPSPTRGNGSKANKKEEDKEEDDDDIPDGPKPMLPYSSMFVLSPTNPIRCAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVEEDSPRNKILNFFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCTDDSKHTSEECKGSFFVYDGTDQLPRREVREWKTQSFHYDNVATAMLTLFAVQTGEGWPQVLQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPNKRNSFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKFHEAPPTLIDILSFMNLVFTFFFLLETIMKLIAFGCKNFFKDPWNIFDFITVIGSIIDALVLELGENSFNVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIELEPESAITRHNNFRSFVQGLMLLFRCATGESWPNIMLACLKGRPCDPRAGKSNET---------CGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDAEGKVGFTTTLFALIRENLNIKMRTAEEMDQADQELRQTISHIWPLQAKKLLDLLVPRKDELNTGKLTVGKIYAGLLILESWRNTKFGQIE 1616 HSP 2 Score: 112.464 bits (280), Expect = 3.245e-21 Identity = 96/373 (25.74%), Postives = 167/373 (44.77%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFF---YCTDESKQT------PDECQG--------YFYIVEDRERPPMVMERNWEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF----------NELGEAELQDDMDKNQKSCIDFAIQARPLELYVPDETSGPRFHI 665
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LGFV+H +Y+R+ WN MD VV I+ + L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G Y ++ Q P C Y+ + M +E+ WE F ++DN AMLT+F T EGW +L D++ ST+ W I+++ ++ FF +N+ + ++ F E + Q ++K +++ +A + L T + HI
Sbjct: 120 TSLFILSEDNIIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPHGDKTLLAQKLEKTEAYFLGIFCVEASLKILALGFVMHKHSYLRNIWNIMDFFVVVTGFITLFPQEGPEVD---LRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHRSCYSLEDISQIVKEGEFPTPCNADNDTIAPTGAYVCNSSDS--MCVEQ-WEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTFN------W------IYFVPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQEFLKLRRQQQLEKELNGYVEWICKAEEVILAEERTTEEEKMHI 474
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|1061101322|ref|XP_017877480.1| (PREDICTED: voltage-dependent calcium channel type A subunit alpha-1 isoform X6 [Ceratina calcarata]) HSP 1 Score: 1302.73 bits (3370), Expect = 0.000e+0 Identity = 665/1129 (58.90%), Postives = 827/1129 (73.25%), Query Frame = 0
Query: 12 SEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAEKERQKQAAEQLLNKD----KAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA----------------------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIE 1098
+EKR R++IR+ K+ ++WFVI LVF NT VAVEHYNQP+WLT+FLYYAEF+FL+ F+LEM I++YALG +F+SSFNRFD +VI+GS+ EV W ++GSFGLS LRALRLLR+FKVTKYW SLRNLVI+L++++ SI+SLLFLLFLFI IFALLGMQLFGG FNF TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG GM+YSLYF++L L G+YTLLNVFLAIA D+L A L+ AE E+ KQ Q L K+ + P++ +P+ EI P + + E + + ++E+++ +P+LPYSS FILS TNP+R HW+V + FD+FIM++I LSSIALA+EDPV E+SPRNK+L Y DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFF+CTDESK T +ECQG +++ ED P +R W + F+YDN AMLTLFAVQT EGW +LQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF IQARPLE Y+P + +F IW +V S PFE FI+ LIV NT+LLM+KFH + + L Y N+ FT LFTVECI K+ +FG RN+F+D+WN FDFITV+GSI+DA ++VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ DPGT ID HNNF+ FF LMLLFRCATGEAWP+IML RPCDP A +K G CGS++ Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ WS YDP+ TGKIHY E+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D KV+FTTTLFALIRENL I VR ++E QA+ ELR TI WP R+ ++LL+P + G G +TVGK+Y +LI ++W+ TKFGQIE
Sbjct: 430 AEKRFRYWIRKSVKSQNFYWFVIILVFFNTVCVAVEHYNQPEWLTDFLYYAEFVFLALFMLEMFIKVYALGPRTYFDSSFNRFDCVVISGSIFEVIWSAL--KSGSFGLSVLRALRLLRIFKVTKYWKSLRNLVISLLSSMRSIISLLFLLFLFILIFALLGMQLFGGQFNFEAGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGG-TKRGMVYSLYFIVLVLFGNYTLLNVFLAIAVDNLANAQELSAAENMEENEDKQKQAQELEKEIQTLQKPKDGNAPKVEICPPSPNQNFKDGKGEKQSSEEEKKQDEDDDTGPKPMLPYSSMFILSPTNPIRRAAHWVVNLRYFDVFIMVVITLSSIALAAEDPVWEESPRNKVLNYFDYAFTGVFTVEMLLKIVDLGIILHPGSYLREFWNIMDAVVVICAAVSFAFDMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFFCTDESKYTKEECQGQYFVFEDNGMLPEPRKREWSTQSFHYDNVMAAMLTLFAVQTGEGWPQILQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIQARPLERYMPRDRKSVKFRIWSIVVSTPFEYFIMCLIVLNTLLLMMKFHRQSDVYKNTLKYMNMCFTGLFTVECILKIAAFGVRNFFKDAWNIFDFITVIGSIVDALVIEFGERLSGMPSGGQLGEKKENFINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNITNDPGTAIDEHNNFQSFFAGLMLLFRCATGEAWPNIMLSCVKDRPCDPKA---SKQQG------GCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWSEYDPNATGKIHYKEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPVDENLKVNFTTTLFALIRENLNIKVRSANERHQANEELRDTIRSIWPLQARKILDLLIPRNEELGRGKMTVGKIYVCLLILESWRSTKFGQIE 1526 HSP 2 Score: 120.168 bits (300), Expect = 1.706e-23 Identity = 93/316 (29.43%), Postives = 152/316 (48.10%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKF----FYCTDESKQTPDECQGYFYIVEDRERPPM---VMERN-------WEKKPF---NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF 621
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F AIF +E SLKIL LGFVLH G+Y+R+ WN MD VV I+ + G L++L+ +RVLRPLK ++ IP L+ V ++ ++ IFA++G++ ++G + D S + Q +++ P V + N WE F ++DN AMLT+F T EGW +L D++ STY W I++I ++ FF +N+ + ++ F
Sbjct: 22 TSLFILSEDNCIRKHTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLAIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAFSQ--GIELDMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDISVIVKEGEQASPCNTDNKSEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYN------W------IYFIPLIVLGSFFMLNLVLGVLSGEF 323 HSP 3 Score: 107.457 bits (267), Expect = 1.073e-19 Identity = 71/278 (25.54%), Postives = 133/278 (47.84%), Query Frame = 0
Query: 7 KRVTRSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDR------AGSFG--------LSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEET--PTSNFNTIVAALLTVFQVLTGEDWNQVMYTAI-----NSKGGRANGGM---IYSLYFVMLTLCGDYTLLNVFLAIACDSLD 260
+ + R K ++F I I ++ + +F++ L+ LNT + ++ + Q L Y F F +E +++ A GV FF ++N FD + + GS+++ + F +R G G + LR R R+ K+ + ++R L+ + + ++ + L+ + FI+A++GMQ+FG N P +NF + A L+ +F+ TGE W +M + + + K + GG I YFV + +LN+F+A+ D+ D
Sbjct: 1087 RYMPRDRKSVKFRIWSIVVSTPFEYFIMCLIVLNTLLLMMKFHRQSDVYKNTLKYMNMCFTGLFTVECILKIAAFGVRNFFKDAWNIFDFITVIGSIVDALVIEFGERLSGMPSGGQLGEKKENFINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNITNDPGTAIDEHNNFQSFFAGLMLLFRCATGEAWPNIMLSCVKDRPCDPKASKQQGGCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFD 1364 HSP 4 Score: 68.1662 bits (165), Expect = 1.132e-7 Identity = 67/312 (21.47%), Postives = 127/312 (40.71%), Query Frame = 0
Query: 30 FWFVIALVFLNTCTVAVEHYNQPKW----LTEFLYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF-------------------------NFPEETP-----------------------TSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEA--EKERQKQAAEQL 283
F + + L + C V + PK L + L E FL+ F +E +++ ALG + ++ + +N D V+ + F L LRA+R+LR K+ SL+ ++ +++ A++ +L + L+ I IFA++G++ + G+ + E P ++F+ I A+LTVFQ +T E W ++Y ++ G N +YF+ L + G + +LN+ L + + E ++ + RQ+Q +L
Sbjct: 46 FEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLAIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAFSQGIEL---DMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDISVIVKEGEQASPCNTDNKSEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYNW-----IYFIPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQSFLKLRRQQQLEHEL 349
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Match: gi|987908412|ref|XP_015429783.1| (PREDICTED: voltage-dependent calcium channel type A subunit alpha-1 [Dufourea novaeangliae]) HSP 1 Score: 1302.73 bits (3370), Expect = 0.000e+0 Identity = 658/1118 (58.86%), Postives = 833/1118 (74.51%), Query Frame = 0
Query: 11 RSEKRLRFFIRRICKTSYWFWFVIALVFLNTCTVAVEHYNQPKWLTEFLYYAEFLFLSAFILEMCIRMYALGVMAFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSFNFPEETPTSNFNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEAE----KERQKQAAEQLLNKDKAPEEDKSPEEEIDPIRAAEMAFERAAEAAARAALQAEEEEEEEEERPILPYSSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASEDPVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRL---KSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKN------------FIFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPFNYDNCFMAMLTLFAVQTSEGWVIVLQDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTFNELGEAELQD-DMDKNQKSCIDFAIQARPLELYVPDETSGPRFHIWKLVTSEPFENFILLLIVCNTILLMLKFHGAPLYFTDILSYFNLVFTLLFTVECIFKLVSFGPRNYFRDSWNTFDFITVVGSIIDA------TKMVSVGFLKLFRAARLIKLLRRSVSVRILLYTFVQSLKVSCGTLSFGALSAIKAFFPQALPYVCMLMGMLFFIYAIVGMQLFGSVMIDPGTTIDRHNNFRHFFQSLMLLFRCATGEAWPDIMLDAGSGRPCDPLAIELNKTTGEPLYVMTCGSSLTYVYFVSFIFLCSFIMLNLFVAVIMDNFDYLTRDSSILGSHHLGEFINTWSNYDPSGTGKIHYTEIFNMLRDIDPPLGYGKKCPERMAYKKLIRMNMPMDMEGKVHFTTTLFALIRENLKINVRESSEMDQADIELRTTIIKCWPHTKREKIELLVPTWKHTGTGHLTVGKLYGGILIYDNWKKTKFGQIEVLRQ 1102
R+E R RF+IR+ K+ ++WFVI LVF NT VAVEHY QP+WLT+FLY+AEF+FL+ F++EM I++YALG +F+SSFNRFD +VI+GS+ EV W ++GSFGLS LRALRLLR+FKVTKYW SLRNLVI+L+N++ SI+SLLFLLFLFI IFALLGMQLFGG FNF TP +NFNT ALLTVFQ+LTGEDWN+VMY I S+GG G M+YSLYF++L L G+YTLLNVFLAIA D+L A L+ AE+ + KE+Q Q E+ + + P++ +P+ EI P + F+ + + ++EE++ +P+LPYSS FILS TNP+R HW+V + FD FIM++I LSSIALA+EDPV EDSPRN++L Y DY FT +FT+E LKI+DLG +LHPG+Y+R+FWN MD VV CA +SF + G+ GQ L KSL++LRVLRPLKTI R+P+LKAVFDCVV SLKN FIFAV+ VQLFNGKFFYCTDESK T +CQG +++ E+ P +R W + F+YDN AMLTLFAVQT EGW +LQ+SM++TYE++GPI FR+EMSIFYIV+FIVFPFFFVNIFVALII+TF E GEAELQD ++DKNQKSCIDF IQARPLE Y+P E + ++ IW++V S PFE FI+ LIV NT+LLM+KFH + + L Y N+ FT +FTVECI K+ +FG RN+F+D+WNTFDFITV+GSI+DA ++VGFL+LFRAARLIKLLR+ ++RILL+TFVQS K ALPYVC+L+ MLFFIYAI+GMQ+FG++ +DP ++I +HNNF+ F Q LMLLFRCATGEAWP+IML GRPCD + EP CGS++ Y YFVSFIF CSF+MLNLFVAVIMDNFDYLTRDSSILG+HHL EF+ W+ YDP+ TGKIHYTE+++ML+++DPPLG+G KCP R+AYKKLIRMNMP+D++GKV+FTTTLFALIRENL I +R ++EM QA+ ELR I WP ++ ++LL+P + G LTVGK+Y +LI ++W+ T+FGQIE Q
Sbjct: 435 RAEMRFRFWIRKSVKSQKFYWFVIVLVFFNTVCVAVEHYGQPQWLTDFLYFAEFVFLALFMMEMFIKVYALGPRTYFDSSFNRFDCVVISGSIFEVIWSAL--KSGSFGLSVLRALRLLRIFKVTKYWKSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNFDYGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHRRG-MVYSLYFIVLVLFGNYTLLNVFLAIAVDNLANAQELSAAEDEQQVEDKEKQAQELEKEIESLQKPKDGNAPKVEICP-PSPNQNFKDGKGGKQSSEEKKQDEEDDTGPKPMLPYSSMFILSPTNPIRRAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVWEDSPRNEVLNYFDYAFTGVFTVEMILKIIDLGIILHPGSYLREFWNIMDAVVVICAAVSFAFNMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCTDESKYTEQDCQGQYFVFEEGAMLPEPKKREWHTQCFHYDNVMAAMLTLFAVQTGEGWPQILQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIQARPLERYMPKERNSVKYKIWRIVVSTPFEYFIMGLIVLNTLLLMMKFHRQSDAYKNTLKYMNMCFTGMFTVECILKIAAFGVRNFFKDAWNTFDFITVIGSIVDALVIEFGENFINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK--------------------ALPYVCLLIAMLFFIYAIIGMQVFGNIALDPESSITKHNNFQSFIQGLMLLFRCATGEAWPNIMLSCIKGRPCD-----VKAGKQEP---GGCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPVDVDGKVNFTTTLFALIRENLSIKMRRANEMKQANEELRDAIRSIWPLQAKKMLDLLIPRSEELGRDKLTVGKIYVCLLILESWRTTRFGQIESTGQ 1520 HSP 2 Score: 118.627 bits (296), Expect = 4.044e-23 Identity = 91/323 (28.17%), Postives = 152/323 (47.06%), Query Frame = 0
Query: 340 SSFFILSSTNPLRVLVHWIVTKKVFDMFIMLIIVLSSIALASED--PVDEDSPRNKILGYADYGFTAIFTLECSLKILDLGFVLHPGAYMRDFWNFMDITVVTCALISFYHTIAGTPTGQRLKSLKLLRVLRPLKTINRIPQLKAVFDCVVISLKNF------------IFAVVGVQLFNGKFFYCTDESKQTPDECQGYFYIVEDRERPPMVMERNWEKKPF------------------------NYDNCFMAMLTLFAVQTSEGWVIVL---QDSMSSTYEEEGPIPWFRVEMSIFYIVFFIVFPFFFVNIFVALIIVTF 621
+S FILS N +R +I+ F+ ++L I+ + + LA E+ P + + + L + F IF +E SLKIL LGFVLH G+Y+R+ WN MD VV ++ + A T L+ L+ RVLRPLK +++IP L+ V ++ ++ IFA++G++ ++G +T + +I++D E+P N + PF ++DN AMLT+F T EGW +L +D++ STY W I++I ++ FF +N+ + ++ F
Sbjct: 22 TSLFILSEDNCIRKHTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLGIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGSMTVF---AETNVDVDLRMLRSFRVLRPLKLVSKIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTL-------HKTCYSIRDINFIMKDGEQPSPCNTDNKIEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWVKDALGSTYN------W------IYFIPLIVLGSFFMLNLVLGVLSGEF 322 HSP 3 Score: 70.8626 bits (172), Expect = 1.591e-8 Identity = 76/337 (22.55%), Postives = 136/337 (40.36%), Query Frame = 0
Query: 30 FWFVIALVFLNTCTVAVEHYNQPKW----LTEFLYYAEFLFLSAFILEMCIRMYALGVM----AFFNSSFNRFDVMVITGSVLEVFWVNFHDRAGSFGLSALRALRLLRVFKVTKYWSSLRNLVIALMNAISSILSLLFLLFLFIFIFALLGMQLFGGSF----------NF-------PEETPTSN-------------------------------FNTIVAALLTVFQVLTGEDWNQVMYTAINSKGGRANGGMIYSLYFVMLTLCGDYTLLNVFLAIACDSLDQAAALTEAEEA--EKERQKQ--------------AAEQLLNKDKAPEEDK 294
F + + L + C V + PK L + L E FL F +E +++ ALG + ++ + +N D V+ + VF D L LR+ R+LR K+ SL+ ++ +++ A++ +L + L+ I IFA++G++ + G+ NF P T N F+ I A+LTVFQ +T E W ++Y ++ G N +YF+ L + G + +LN+ L + + E ++ + RQ+Q A E +L +++ EE+K
Sbjct: 46 FEYAVLLTIIANCVVLALEEHLPKHDKTILAQKLEATEIYFLGIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGSMTVFAETNVD----VDLRMLRSFRVLRPLKLVSKIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDINFIMKDGEQPSPCNTDNKIEAPFGAHVCDANVSTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWVKDALGSTYNW-----IYFIPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQSFLKLRRQQQLEHELICYLNWICKAEEVILAEERTTEEEK 373 The following BLAST results are available for this feature:
BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 17
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BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of voltage-dependent calcium channel type a subunit alpha-1 isoform x7 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold210_size256293:190310..216330+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold210_size256293-snap-gene-1.25 ID=maker-scaffold210_size256293-snap-gene-1.25|Name=voltage-dependent calcium channel type a subunit alpha-1 isoform x7|organism=Tigriopus kingsejongensis|type=gene|length=26021bp|location=Sequence derived from alignment at scaffold210_size256293:190310..216330+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'voltage-dependent calcium channel type a subunit alpha-1 isoform x7' has the following synonyms
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