Query:    5 TVSEQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDS--IDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTV 509
             +  + ++ + G  +  ++ ++ DV +PA   +  +VP ++  E++ AV++A  A   W+  +P  R +V+ K+  L+  +M ++A+ ++RE GKT +DA+GDV RGL+V E C    +LL GE        +DL S   PLG+ AGI PFNFPAMIP+W F  A   GN++I K SER PT  M L EL+ EAG+P GV N++HG   AV+ I  HPDI A+ FVG     +++Y++G AN KRVQC  GAKNH +I PDA+ E   + LVG+ FGAAG+RCMA++ AV VG   A   +  +  +   L V   SAG     D+GP+++  +  R+                          L+ S    GA++ +DGR+   + + +G ++GP +   +  +M+ Y+EEIFGPVL V+  +  ++A+ L   N YGNGTAI+T +G TAR F   ++VG VGVNVPIPVPL   +F G + S  GD + +G  A  F+T+TKTV
Sbjct:  840 NIPSKTQNFINGKFIDSSTSKWIDVHDPANNEIVTRVPQSTNTEMENAVESAKAAFKTWSKTSPLSRQQVMFKYQALIKENMSEIAKLITREQGKTHSDAEGDVLRGLQVVEQCCANTNLLMGENLPGITKDMDLISYHTPLGICAGIAPFNFPAMIPLWMFPMAXICGNTYIXKXSERXPTACMALVELLKEAGMPDGVXNIIHGQHDAVNFICDHPDIRAISFVGGDAAGKHIYNRGSANGKRVQCNMGAKNHGVICPDANKEYTINQLVGSAFGAAGQRCMALTTAVLVG--NAQSWINDIKEKASKLVV---SAGSDPGADFGPVISPQSKQRI------------------------NDLIQSASNDGADIILDGRNITVDKYPNGNFVGPTIISNMTENMEAYKEEIFGPVLCVINVETLDDAIELINKNRYGNGTAIFTNNGATARKFTQDIDVGQVGVNVPIPVPLPMMSFTGSRGSFLGDSHFYGKQAIGFFTQTKTV 1317          

Query:   24 GRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQA---QLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAIL-QHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDA-DLEQAADALVGAGFGAAGERCMAIS---VAVPVGAETADKLMELLIPRVQALKVG-PYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHT-FGGWKKSGFGDLNQHGPDAFRFYTRTKTVT 510
            G   D   PAT  V  +V   S  ++D AV  A +A      W  ++   R R++ K   ++ RD   LA+  + ++GK  + A  DV+  + V  +  G    + G      G     Y+ ++P+GV   I P+N+P  +  WK+ PA+A G + +LKP+E+ P   + +A L  E G P GV+NVV GD     A L QH D+  + F GST + + + S   +N KRV    G K+ +++M D   L++A      A F   G+ C A S   V   +  E   K  EL    V+  K+G P+ +    DYGP V+ + + ++  L++SGV  GA++                 +A G+            G   G++I P +F  V  +M I +EEIFGPV S+   +  +E +S A   PYG    I T+  D    F   +  G V VN      L+  T FGG+K+SG+G   + GP+  + Y  +KTVT
Sbjct:   22 GSTFDTIXPATEEVIAKVAFGSKGDIDKAVIAARRAFDPTSEWRTMDXSNRGRLMYKLADVMERDRIILAKLDTVDNGKPYSTALEDVEGSIGVIRYYAGYADKIHGSTIPVDG-NFFTYTRQEPVGVVGQIIPWNYPVAMISWKWGPALATGCTMVLKPAEQTPLSALYMAALTKEVGFPKGVINVVTGDGQQTGAALSQHMDVDKIAFTGSTEVGKLITSNA-SNLKRVSLELGGKSPLVVMNDCPSLDEAVQICHDAIFANMGQNCCAGSRTFVQSDIYEEFVKKSSEL----VKKKKIGCPWDS--QTDYGPQVSKEHMGKILDLINSGVKEGAKV-----------------MAGGS-----------RGGSKGYFIQPTVFCDVKDNMRIAKEEIFGPVQSIFVFETLDEVISRANSTPYGLAAGILTQKLDNITKFTQNIRAGSVWVNCYD--YLSPQTPFGGFKQSGYG--RELGPEGIKCYLESKTVT 478          

Query:   23 SGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQA---QLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVD-AILQHPDIAAVGFVGSTPIARYVYSQGC-ANDKRVQCFGGAKNHMIIMPDA-DLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVG-PYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELA--------VDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVN 469
            +G   +  +P+T  V  +V   SA +++ AV  A +A      W  ++   R + ++    L+ RD+D LA+ ++ ++GK I  ++ +VQ  ++V  +  G    + G      G  +  Y+ ++P+GV   I P+N+P  +  WK+ PA+  G + +LKP+E+ P   + +A L+ EAG P GV+NVV GD      A++++ D+  + F GST + + + S G  +N KR+    G K+ +++M D   L++A +    A F   G+ C A S  V V +   D+ +       +   VG P+++ +   +GP V  + + ++  L+DSGV  GA++         V+ + + ++  L+D+GV  GA++   G     +    G ++ P  F  V   M I +EEIFGPV S+ + +   E +  A D  YG    I T D +T   F   +  G V +N
Sbjct:   23 NGATFETIDPSTEEVVAKVAFGSANDMNKAVNAAKKAFEPNSEWRTMDASMRGKFILTLADLMERDVDILAKLITIDNGKPIDTSEFEVQFAIKVFRYYAGYADKIHGSTIPVDGNFMS-YTRKEPIGVVGQIIPWNYPLAMISWKWGPALTTGCTMVLKPAEQTPLSALHMASLVKEAGFPKGVINVVTGDGPQTGAALVKNLDVDKIAFTGSTEVGKLISSSGXDSNLKRISLELGGKSPVVVMNDCPSLDEAVEICQNAIFTYMGQVCXAGS-RVFVQSGIYDEFVRKSTELAKKRTVGSPWNSKNL--HGPQVNQEQMDKILDLIDSGVKEGAKIXSKNLHGPQVNQEQMDKILDLIDTGVKEGAKIETGGSRXGTK----GXFVEPTXFSSVKDDMRIAKEEIFGPVQSIFKFETLNEVIDRANDTTYGLAAGIITSDFNTMNKFSSFIRAGTVWIN 476          

Query:   26 FADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKG-DVQRGL-EVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVH--GDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFG 490
            + D FNPATG +  Q+P ++A+ VD +V  A  A   WA ++ ++RA  L+K   LL   +D+ A   S++ GK ++ AK  D+ R +  +  F    P+L +          I+ YS R P+GVAA I+P+N P  +  +K  PA+ AGN+ + KPSE        L  +  E GLP GV+N++   G KT  +A+++HP I A+ F GS+     +        K++    G KN  II  DAD+++A +  + A F   GE C+ I   + V     ++  +  + + + LKVG  +  D +  GPL++++   +VR  VD  V  GA +     A                    +   F+   F DG++  P +   +  S  I +EEIFGPV+ +      EE +  A D  YG    ++T D   A      + VG V VN  +   L    FGG K+SG G
Sbjct:   18 YLDSFNPATGKIWAQIPDSNADIVDRSVVAAKSASRNWAXLSYEKRAAYLIKAADLLESRLDEFAILESQDQGKPVSLAKKVDIPRAIYNLRCFAHCWPYLREXSTVQPEFHAIN-YSTRSPVGVAALISPWNLPLYLLTFKIAPALMAGNTVVXKPSEITSVTAWKLCHIFDEIGLPRGVVNLICGLGGKTG-EALIKHPTINAISFTGSSKTGSKIAGIAAPLMKKLSLELGGKNPGIIFEDADIDKAINTFIRACFMNQGEVCLCIE-RLFVQESIFEEFKDKFVAKTKKLKVGDPNDPD-VFMGPLISSEHQEKVRYYVDLAVKEGANIECGEPA--------------------NHMGFLDSKFTDGYFFPPTIITGIADSSPIMKEEIFGPVVCITPFSTPEEVIQRANDVEYGLCAXVFTNDIHLAHKTAAALEVGTVWVNSWLIRDLTM-PFGGMKQSGMG 461          

Query:   11 KHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDK---TAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAIS-VAVPVGA-ETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNV-PIPVPLAYHTFGGWKKSGFG-DLNQHGPDAFRFYTRTKTV 509
            K  V G     T+G    V NP+ G+    VP  +  +  +A++ A++A   W     + R+ VL  F    N + D+LA+ L+ E GK +A+AKG++  G    E+         G+   S     +   +R+P+GVAA ITP+NFP  +   K   A+A+G + ++KPS   P   +  A L  EAG+P GV+NVV   +   +  +A+     I A+ F GST + + +Y+Q  +  K++    G     I+   A+++ A   L+ + F  AG+ C++ + + +  G  ET  K +E  + +   L  G  S    ++ GPL+    +  +  LV   +  GAE+A          S  DSG                       +  P +   V   M I+ EEIFGPV+S+++ +N EE + LA D   G     Y+ D         ++  GMVGVN   I  P    TFGG K+SG G + +++G D    YT  K +
Sbjct:   32 KAFVDGKWXPSTTGTNFPVHNPSDGSFLLSVPDMNETDTQSAIEVASKAFKTWKETTGKERSIVLRNFFNKCNENQDELAKILTLEQGKPLAEAKGEILYGNSYLEWFSEEARRAYGDVVPSPDRKKEFILVREPIGVAAMITPWNFPNAMLARKVGAALASGCTCVVKPSPDTPLSALAFASLAKEAGVPDGVINVVTTSQNLESVSNALCSSNVIKALSFTGSTRVGKLLYNQCSSTVKKLSLELGGNAAFIVFDSAEIDNAVKGLMASKFRNAGQTCVSSNRIFLQSGIYETFLKKLEASMKKDLVLGDGMCSG---VNQGPLINERQIQNIEDLVSDALNKGAEIATGG-------SRGDSG---------------------SLFYEPTIIKNVKPDMRIFHEEIFGPVVSIIQFNNEEEVIELANDTQVGLAGXFYSNDIKQCWRVARKMETGMVGVNEGAISAPEI--TFGGVKESGIGREGSKYGLDE---YTEIKYI 501          

Query:   63 WAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKG-DVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHG-DKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMA---ISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFG-DLNQHGPDAFRFYTRTKTVTSR 512
            W   +   R R+L K   L+ RD + LA   + ++GKT  D+   D+   ++   +  G    + G+     G     Y+  +P+GVA  I P+NFP ++  WK  PA+A GN  ++K +E+ P   + +A+L  EAG P GV+N++ G   TA  AI+ HP +  + F GST + + +  +     KR     G KN  II  DAD + A        F   G+ C A   I V   +  +  +K +EL   RV      P +A      GP V  D    V + +  G   GA+L                 VA G   +VDG          G ++ P +F  V   M I REEIFGPV  + +  + EE ++ A +N YG    ++T D D A      +  G V VN       A   FGG+K+SG G +L ++G    + YT TK + ++
Sbjct:   95 WRNTDASERGRLLYKLADLIERDREYLASLETLDNGKTFQDSYYVDLDLVIKCYRYYGGWADKVHGKVIPVDG-NFFAYTRHEPVGVAGQIIPWNFPLLMQAWKLAPALATGNCVVMKLAEQTPLTGLYIAQLTKEAGFPDGVVNIIPGYGHTAGAAIVNHPHVDKIAFTGSTAVGKIIQKEAADTLKRXSLELGGKNPSIICDDADFDYAVATAHNGLFFNQGQVCCAGSRILVQENIYNDFVEKSVELAKKRVVGNPFDPNTA-----QGPQVDQDQYNTVLNYIKLGNNDGAKL-----------------VAGGK--SVDGH---------GXFVQPTVFADVGDDMRICREEIFGPVQVIQKFKSLEEVVNRANNNNYGLSAGVFTNDLDKAHYISQSLRAGTVWVNT-FNTFCASIPFGGYKESGIGRELGEYG---LQNYTETKCIMTK 512          

Query:   12 HLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFC-IGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEG-FEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNV-PIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTV 509
            H + G +  G   +F +   P +G    +V +A A++VD AV                              + MD L      ++GK I +A+ D+   +   E+    A +  +GE+   AG G   Y  ++P+G+ AGI  +N+P     WK  PA+A+GN+FI KPS+  P   + LAE + EAGLP GV N++ G+      +  HPD++ + F GS      +   G    + V    G K+ +II  DADL+ A    + A F + G+ C +    V V      + ++  + +V  LKVG                D L       D+ V A     +  +   RV   +      GA++   G   V +G    G Y+ PC+   V+ S    +EEIFG V  V    +  E +S A D P+G    ++T++ + A      ++ G+V VN   I  P     FGG+K SG G   ++G  A  +YT+TKT 
Sbjct:   19 HWINGKRFEGCGSKFFENKEPRSGQTLCKVGIAEAKDVDEAV------------------------------KIMDVL------DNGKPIWEARMDMDSVIGALEYYGAYANNGFQGEYYKLAG-GSFAYVTKEPIGLVAGIGAWNYPLQTATWKVAPALASGNTFIYKPSQFTPLTALYLAEALKEAGLPDGVFNIIQGEGETGALLSSHPDVSKLSFTGSIATGTKIMKAGADGIRHVTLELGGKSPLIIFDDADLKNAVKGALMANFFSQGQVC-SNGTRVFVQKGVYHEFLQEFVRQVTNLKVG----------------DPLKE-----DTTVGA----TIHPEHAERVLQYIKEAKEEGAKIECGGEKIVIDGDLSGGSYVSPCILSNVEDSFKCVKEEIFGAVAXVXPFXSEXEVVSRANDTPFGLAGGVFTKBLNRAHRIADSIDAGVVWVNTFNICTPEV--PFGGYKMSGIG--RENGKAAIEYYTQTKTT 452          

Query:   32 PATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPM-------MLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSID----YGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFED--GFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRD 450
            PA      QV   S ++ +  V++A +A   WA +    R  ++ +    L   +  L + +S E GK + +  G+VQ  +++ ++  G   ++ G++  S  PG  L     PLGV   I+ FNFP  +  W    A+ AG++ I K    AP+ P+       ++ E++ + G+P  V  +  GD      + +   I  V F GST + R V         +     G  N +I+  DA+++    +   A  G AG+RC  +   + V  +  D+++  L    +A +      GD ++    YGPL + + +   +  +   VAAG ++                             +F  +  ED  G Y+ P +   +     +   E F P++ +++  + +EA+    +   G  ++++T D
Sbjct:  273 PANNQPIAQVKTGSVQDFERCVKSAEEAWQKWADLTAPARGEIVRQIGDALREKIVPLGKLISMEMGKIVPEGVGEVQEFVDICDYACGLSRMIPGKYIPSERPGHALIESWNPLGVIGVISAFNFPVAVYGWNNAIALIAGDTVIWK---GAPSTPLTSVATIKIVTEVLEKNGIPGAVCALCQGDADVGQKMAEDKRIKLVSFTGSTEVGRKVAVTVQQRFGKHLLELGGNNALIVDKDANIDMVITSATFACVGTAGQRCTTLRRLI-VHEDVYDEVVRRL---TKAYETVIKRIGDPLEDGTLYGPLHSKNGIEAYKKTIQDAVAAGGKI-----------------------------EFGGKVIEDRPGNYVEPTIITGLAHDSPVVMRETFAPIVHILKTKSLDEAIQWNNEVEQGLSSSLFTSD 668          

Query:   71 RARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVD-AILQHPDIAAVGFVGSTPIARYVYSQGC-ANDKRVQCFGGAKNHMIIMPDA 266
            R + ++    L+ RD+  LA+ ++ ++GK I  +  +VQ  ++V  +  G    + G      G  +  Y+ ++P+GV   I P+N+P  +  WK+ PA+  G + +LKP+E+     + +A L+ EAG P GV+NVV GD      A++++ D+  + F GST + + + S G  +N KR+    G K+ +++M D 
Sbjct:    2 RGKFILTLADLMERDVGILAKLITIDNGKPIDTSVFEVQSAIKVFRYYAGYADKIHGSTFPIDGNFMS-YTRKEPIGVVGQIIPWNYPLAMISWKWGPALTTGCTLVLKPAEQTTLCALHMASLVKEAGFPKGVINVVTGDGPQTGAALVKNLDVDKIAFTGSTGVGKLISSSGNDSNLKRISLELGGKSPVVVMNDC 198          

Query:   13 LVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVD-AILQHPDIAAVGF 229
            + G V +  TS    + F  A      +    S EE   A + A +    W  ++   R + ++    L+ RD+D LA+ ++ ++GK I  +  +VQ  ++V  +  G    + G      G  +  Y+ ++P+GV   I P+N+P  +  WK+ PA+  G + +LKP+E+ P   + +A L+ EAG P GV+NVV GD      A++++ D+  + F
Sbjct:    1 MSGKVDIKYTSLFIDNEFLEAENGATFETIDPSTEEAVNAAKKAFEPNSEWRTMDASMRGKFILTLADLMERDVDXLAKLITIDNGKPIDTSVFEVQYAIKVFRYYAGYADKIHGSTIPVDGNFMS-YTRKEPIGVVGQIIPWNYPLAMISWKWGPALTTGCTMVLKPAEQTPLSALHMASLVKEAGFPKGVINVVTGDGPQTGAALVKNLDVDKIAF 217          

Query:   10 IKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDS--IDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPS-GVKEGAEFSIPVM 528
            + HL+ G  VA  +GR ADVFNP+TG    +VPLA  + +  A+  A  A  AW    P +RA+VL +F  LL ++  ++++ +S EHGKT+ DA G+++RG+E  E+   AP +LKGE++ + GP ID +S  QP+GV AGITPFNFPAM+P+W +  AIA GN+FILKPSER P+  +++AEL  EAGLP GVLNVVHGDK AVD +LQ P++ A+ FVGSTPIA Y+Y++G    KRVQ  GGAKNH ++MPDADL+ A  AL+GA +G+ GERCMAISVAV VG + AD L+  L+P+++ALK+G   AG S  +D GPLVTA A  +V   +DSGVA                         GAEL VDGR +   G E+GF++G  LFD+V   M IY+EEIFGPVL VVR ++ EEA+ L  D+ YGNGT I+TRDG+ AR F   + VGMVGVNVP+PVP+AYH+FGGWK+S FGDL+ +GPD  RFYTR K +T RWP     E ++F+ P +
Sbjct:    4 LHHLINGEMVA-DNGRSADVFNPSTGEAIHKVPLADGKTLQKAIDAARAAFPAWRNTPPAKRAQVLYRFKQLLEQNEARISKLISEEHGKTLEDAAGELKRGIENVEYACAAPEILKGEYSRNVGPNIDAWSDFQPIGVVAGITPFNFPAMVPLWMYPLAIACGNTFILKPSERDPSSTLLIAELFHEAGLPKGVLNVVHGDKEAVDGLLQAPEVKAISFVGSTPIAEYIYAEGTKRGKRVQALGGAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMAISVAVCVGDQVADALIAKLVPQIKALKIG---AGTSCGLDMGPLVTAAAQAKVTGYIDSGVA------------------------QGAELVVDGRGYQVAGHENGFFLGGSLFDRVTPEMTIYKEEIFGPVLCVVRVNSLEEAMQLINDHEYGNGTCIFTRDGEAARLFCDEIEVGMVGVNVPLPVPVAYHSFGGWKRSLFGDLHAYGPDGVRFYTRRKAITQRWPQRASHEASQFAFPSL 497          

Query:    6 VSEQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRW-PSGVKEGAEFSI 525
            +S  ++HL+ G  V G   +   V NP   +   ++  ASAE+V+ AV +A +   +W       RARV++++  LL    D+LA+ +S E GKT  DAKGDV RG+EV E     P LL GE  ++    ID YS+ QPLGV  GITPFNFPAMIP+W F  AIA GN+FILKPSE+ P   + LAEL LEAG P GVL VVHG K  VD +L+HP + AV FVGS  + +YVY  G A++KRVQ F GAKNHM+IMPDAD  Q    LVGA  GAAG+RCMAISVAV VGA  A + +  +   +  ++ GP+    +  YGP++   A  R+  L                        +  GV  GA+L +DGR +  EG+ DG ++GP LF  V   M IYREE+FGPVL +   D+ E+A+ L  ++PYGNGT+I+T  G  AR+F H + VG VG+N+PIPVPL + +F GWK S +GDL+ +G    RFYT TKTVT+RW  S    G  FSI
Sbjct:    1 MSVPVRHLIAGAFVEGLGAQRIPVSNPLDNSTLAEIACASAEQVEQAVASARETFASWKETPVSERARVMLRYQALLKEHHDELAKIVSSELGKTFEDAKGDVWRGIEVVEHACNVPSLLMGETVENVARNIDTYSITQPLGVCVGITPFNFPAMIPLWMFPLAIACGNAFILKPSEQVPLTSVRLAELFLEAGAPKGVLQVVHGGKEQVDQLLKHPQVKAVSFVGSVAVGQYVYHTGTAHNKRVQSFAGAKNHMVIMPDADKAQVISNLVGASVGAAGQRCMAISVAVLVGA--AREWIPEIRDALAKVRPGPWDDSGA-SYGPVINPQAKARIERL------------------------IGQGVEEGAQLLLDGRGYKVEGYPDGNWVGPTLFAGVRPDMAIYREEVFGPVLCLAEVDSLEQAIRLINESPYGNGTSIFTSSGAAARTFQHHIEVGQVGINIPIPVPLPFFSFTGWKGSFYGDLHAYGKQGVRFYTETKTVTARWFDSDSVAGTNFSI 494          

Query:   10 IKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDS--IDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIP 526
            +K  + G  V   S ++ D+ NPAT  V  +VP ++  E+DAAV++  +A  AWA  +   R +VL+++  L+  ++ ++A  ++ E GKT+ADA+GDV RGL+V E       L+ GE   S    +DLYS R PLGV AGI PFNFPAMIP+W F  A+  GN+F++KPSER P   M+LA+L+ ++G P G LN++HG   AV+ I  HPDI A+ FVGS     Y++ +G  N KRVQ   GAKNH ++MPDA+ E   + LVGA FGAAG+RCMA+S A+ VG   A K +  L+ R + L+V   +AGD    D GPL+T  A  RV +L+D                        SG   GA + +DGR    +G+E+G ++GP +   V  SM  Y+EEIFGPVL V+  +  +EA+ +  DNPYGNGTAI+T +G TAR + H V+VG VGVNVPIPVPL   +F G + S  GD N +G    +FYT+ KT+TS+W    +E A  S P
Sbjct:   40 VKLFIDGKFVESKSDKWIDIHNPATNEVVGRVPQSTKAEMDAAVESCKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHDAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGE--AKKWLPELVDRAKNLRV---NAGDQPGADLGPLITPQAKERVCNLID------------------------SGTKEGASILLDGRRIKVKGYENGNFVGPTIISNVKPSMTCYKEEIFGPVLVVLETETLDEAIKIVNDNPYGNGTAIFTTNGATARKYAHMVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWK---EEDATLSSP 526          

Query:   10 IKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDS--IDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIP 526
            +K  +GG  V   S ++ D+ NPAT  V  +VP A+  E+DAA+ +  +A  AWA  +   R +VL+++  L+  ++ ++A+ ++ E GKT+ADA+GDV RGL+V E       L+ GE   S    +DLYS R PLGV AGI PFNFPAMIP+W F  A+  GN+F++KPSER P   M+LA+L+ ++G P G LN++HG   AV+ I  HPDI A+ FVGS     Y++ +G  + KRVQ   GAKNH ++MPDA+ E   + LVGA FGAAG+RCMA+S AV VG   A K +  L+   + L+V   +AGD    D GPL+T  A  RV +L+D                        SG   GA + +DGR    +G+E+G ++GP +   V  +M  Y+EEIFGPVL V+  +  +EA+ +  +NPYGNGTAI+T +G TAR + H V+VG VGVNVPIPVPL   +F G + S  GD N +G    +FYT+ KT+TS+W    +E A  S P
Sbjct:   40 VKLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGE--AKKWLPELVEHAKNLRV---NAGDQPGADLGPLITPQAKERVCNLID------------------------SGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWK---EEDATLSSP 526          

Query:    4 TTVSEQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRW 513
            TT  + +K+ +GG  V   SG+   V NPATG V   VP++S EE+D AV+ A +A   W      RRAR+L K+  LL    ++LA  ++ E+GK+  +A G+VQRG+E  EF  GAP L+ G        GI+    R P+GV  GITPFNFP M+P W F  AIA GN+F+LKPSER P +   LAEL  EAGLP GVLN+VHG    V+ +L+HPD+ A+ FVGS P+  YVY    A+ KRVQ   GAKNH I+MPDADL  A   ++ A FG+AGERCMA SV V VG E AD+L+E L+     LK+G     +S+  GP++      R    ++ G   GA L  D           D+ V                  ++G++IGP +FD+V T M I+++EIF PVLS+VR +  +EA+ +A  +P+ NG  IYTRDG   R F   ++ GM+GVN+ +P P+A+  F GWK S +GDL+ +G D   FYTR K +TSRW
Sbjct:    2 TTGVQTLKNYIGGQWVESRSGKTEAVPNPATGEVLAYVPISSREELDEAVRAAKEAFKTWRKTPVPRRARILFKYQQLLVEHWEELARLVTLENGKSYNEAYGEVQRGIECVEFAAGAPTLMMGRQLPDIATGIESGMYRYPIGVVGGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPMLANRLAELFKEAGLPDGVLNIVHGAHDVVNGLLEHPDVKAISFVGSQPVGEYVYKTAAAHGKRVQALTGAKNHSIVMPDADLNVAVREIINAAFGSAGERCMAASVVVAVG-EIADELVEKLVAAANELKIG-NGLEESVFLGPVIREAHKQRTVKYIELGEKEGAILVRDGRK--------DAAVQ-----------------DNGYFIGPTIFDRVTTDMTIWKDEIFAPVLSIVRVETLDEAIEVANKSPFANGACIYTRDGGNVRKFREEIDAGMLGVNLGVPAPMAFFPFSGWKNSFYGDLHANGMDGVEFYTRKKMMTSRW 484          

Query:   10 IKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDS--IDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIP 526
            +K  + G  V   S ++ D+ NPAT  V  +VP ++  E++AAV    +A  AWA  +   R +VL+++  L+  ++ ++A  ++ E GKT+ADA+GDV RGL+V E       L+ GE   S    +DLYS R PLGV AGI PFNFPAMIP+W F  A+  GN+F++KPSER P   M+LA+L+ ++G P G LN++HG   AV+ I  HPDI A+ FVGS     Y++ +G  N KRVQ   GAKNH ++MPDA+ E   + LVGA FGAAG+RCMA+S AV VG   A K +  L+ R + L+V   +AGD    D GPL+T  A  RV +L+D                        SG   GA + +DGR    +G+E+G ++GP +   V  SM  Y+EEIFGPVL V+  +  +EA+ +  DNPYGNGTAI+T +G  AR + H V+VG VGVNVPIPVPL   +F G + S  GD N +G    +FYT+ KT+TS+W    +E A  S P
Sbjct:   40 VKLFIDGKFVESKSDKWIDIHNPATNEVVGRVPQSTKAEMEAAVAACKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGE--AKKWLPELVERAKNLRV---NAGDQPGADLGPLITPQAKERVCNLID------------------------SGAKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPSMTCYKEEIFGPVLVVLETETLDEAIKIVNDNPYGNGTAIFTTNGAIARKYAHMVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWK---EEDATLSSP 526          

Query:   10 IKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDS--IDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIP 526
            +K  + G  +   S ++ D+ NPAT  V  +VP ++  E+DAAV +  +   AWA  +   R +VL+++  L+  ++ ++A  +  E GKT+ADA+GDV RGL+V E       L+ G+   S    +DLYS R PLGV AGI PFNFPAMIP+W F  A+  GN+F++KPSER P   M+LA+L  ++G P G LN++HG   AV+ I  HPDI A+ FVGS     Y++ +G  + KRVQ   GAKNH ++MPDA+ E   + LVGA FGAAG+RCMA+S A+ VG   A K +  L+ R + L+V   +AGD    D GPL+T  A  RV +L+D                        SG   GA + +DGR    +G+E+G ++GP +   V  +M  Y+EEIFGPVL V+  D  +EA+ +  DNPYGNGTAI+T +G TAR + H V+VG VGVNVPIPVPL   +F G + S  GD N +G    +FYT+ KT+TS+W    +E A  S P
Sbjct:   42 VKLFIDGKFIESKSDKWIDIHNPATNEVIGRVPESTKAEMDAAVSSCKRTFPAWADTSILSRQQVLLRYQQLIKENLKEIARLIMLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGDTMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLFQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGE--AKKWLPELVERAKKLRV---NAGDQPGADLGPLITPQAKERVCNLID------------------------SGTKEGASILLDGRSIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETDTLDEAIKIVNDNPYGNGTAIFTTNGATARKYSHLVDVGQVGVNVPIPVPLPMFSFTGSRASFRGDTNFYGKQGIQFYTQLKTITSQWK---EEDASLSSP 528          

Query:    4 TTVSEQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRW 513
            TT  + +K+ +GG  V   S +   V NPATG V   VP+++ E++D AV  A +A   W+     RRAR+L K+  LL    ++LA  ++ E+GK+  +A G++QRG+E  EF  GAP L+ G    S   GI+    R P+GV  GITPFNFP M+P W F  AIA GN+F+LKPSER P +   LAEL  EAGLP GVLN+VHG    V+ +L+HPD+ A+ FVGS P+  YVY    A+ KRVQ   GAKNH I+MPDADL+ A   ++ A FG+AGERCMA SV V VG + AD+L+E L+     +K+G     +S+  GP++      R  + ++ G   GA L  D                         +D   +G  +G++IGP +FD+V T M I+++EIF PVLS+VR    +EA+ +A  +P+ NG  IYTRDG   R F   ++ GM+GVN+ +P P+A+  F GWK S +GDL+ +G D   FYTR K +T+RW
Sbjct:    2 TTGVQTLKNYIGGQWVESRSAKTEAVPNPATGEVLAYVPISTREDLDRAVAAAKEAFKTWSKTPVPRRARILFKYQQLLVEHWEELARLVTLENGKSYNEAYGEIQRGIECVEFAAGAPTLMMGRQLPSIATGIESGMYRYPIGVVGGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPMLANRLAELFKEAGLPDGVLNIVHGAHDVVNGLLEHPDVKAISFVGSQPVGEYVYKTAAAHGKRVQALTGAKNHSIVMPDADLKVAVREIINAAFGSAGERCMAASVVVAVG-DIADELVERLVAAANEIKIG-NGLEESVFLGPVIREAHKQRTVNYIELGEKEGAILVRDGR-----------------------KDAAVQG--EGYFIGPTIFDRVTTDMTIWKDEIFAPVLSIVRVSTLDEAIEVANKSPFANGACIYTRDGGNVRKFRDEIDAGMLGVNLGVPAPMAFFPFSGWKNSFYGDLHANGMDGVEFYTRKKMLTARW 484          

Query:    1 MANTTVSEQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGR-DFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRW 513
            M  TTV + +K+ +GG  +   + +  DVFNPATG V  QVP+++ E+V  A++ A +A   W  V   +RAR+L K+  LL    ++LA+ ++ E+GK  A+A G+VQRG+E  EF  GAP L+ GE   S    ++    R P+GV  GITPFNFP M+P W F  AIA GN+F++KPSER P +   LAEL+ EAGLP GV N+VHG    V+ +L H  +AA+ FVGS P+A YVY +G  N KRVQ   GAKNH I++ DA+LE A   ++ A FG+AGERCMA SV V V  + AD+ + LL  +   +K+G                       + +D GV  G    +      R    ++SG   GA L  DGR D   +  ++G+++GP +FD V + M I+++EIF PVLS+ R +N EE + LA ++ + NG  I+TRDG + R F   ++ GM+GVN+ +P P+A+  F GWK S +GDL+ +G D  +FYTR K +T++W
Sbjct:    1 MTQTTV-KNVKNYIGGEWIESRTEKTEDVFNPATGEVIAQVPISTTEDVHHAIEVANEAFKTWKEVPVPKRARILFKYQQLLVEHWEELAKLITLENGKNYAEAYGEVQRGIENVEFATGAPSLMMGEQLASIATELESGVYRYPIGVIGGITPFNFPMMVPCWMFPMAIATGNTFVMKPSERTPLLANRLAELLEEAGLPNGVFNIVHGAHDVVNGLLDHKKVAAISFVGSQPVAEYVYKRGTQNLKRVQALAGAKNHSIVLSDANLENATTQILNAAFGSAGERCMAASV-VAVEEDVADEFVTLLTQKANEIKIG-----------------------NGLDEGVFLGP--VIRDQHKERTLQYIESGEEEGANLVRDGRTDEAAK--QEGYFVGPTIFDHVTSEMKIWQDEIFAPVLSIARVNNLEEGVDLANESRFANGACIFTRDGGSVRRFRETIDAGMLGVNIGVPAPMAFLPFSGWKDSFYGDLHANGKDGLQFYTRKKVLTTKW 485          

Query:    4 TTVSEQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRW 513
            TT  +++K+ + G  V  T      V NPATG +   VPL+  E+V+ AV+ A  A   W+ V    R+R+L K++ LL  + D+L++ ++ E+GKT+ DA G+VQRG+E  E    AP+L+ G+   +   GID    R PLGV AGITPFNFP MIP+W F  AIA GN+F+LK SER P +   L EL  EAG P GVLN+V G K  V++IL++ +I AV FVGS P+ARYVY  G    KRVQ   GAKNH I+MPD +LE+    ++G+ FG++GERCMA SV V V  E AD+ ++ L+   + LKVG     ++   GPL+      RV   ++SG                        VA GA L VDGR  + E  E G+++G  +FD V+ +M I+++EIF PVLS+VR  + EE + L   + + NG  IYT  G  A++F   ++ GM+GVNV +P P+A+  F G K S +GDL  +G D  +FYTR K VT RW
Sbjct:    3 TTEIKRVKNHINGEWVESTGTEVEAVPNPATGKIIAYVPLSPKEDVERAVEAAKNAYETWSKVPVPNRSRMLYKYLQLLQENKDELSKIITLENGKTLKDASGEVQRGIEAVELATSAPNLMMGQALPNIAGGIDGSIWRYPLGVVAGITPFNFPMMIPLWMFPLAIACGNTFVLKTSERTPLLAERLVELFYEAGFPKGVLNLVQGGKEVVNSILENKEIQAVSFVGSEPVARYVYETGTKYGKRVQALAGAKNHAIVMPDCNLEKTVQGVIGSAFGSSGERCMACSV-VAVLDEIADEFIDALVSETRKLKVGDGFHEENY-VGPLIRESHKERVIGYINSG------------------------VADGASLLVDGRQ-IKEDVEGGYFVGATIFDGVNQNMKIWQDEIFAPVLSIVRVRDLEEGIQLTNQSKFANGAVIYTSSGKHAQTFRDHIDAGMIGVNVNVPAPMAFFAFAGNKASFYGDLGTNGKDGVQFYTRKKVVTERW 485          

Query:   10 IKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVME 529
            I H +GG +V GTSGR ADVFNPATG V+ QVPLASA+E++AA++NA QAQ AW A NPQ+RARV+MKFV LL+RDMDKLAEALSREHGKTI DAKGDV RGLEVAE+CIGAP +LKGEF++ AGPGID++S++QPLGVAAGITPFNFPAMIPMWKFCPAI  GN+FILKPSER P+VP+MLAELM EAGLP G+LNVVHGDK AVD IL HPDI AVGFVGSTPIA YVY++GCAN KRVQCFGGAKNHMIIMPDAD++Q  DAL+GAG+GAAGERCMAISVAVPVG +TA++LME L PRV+ALK+ PY+AGD  D+GPLVT +A TRV+  +D G                        V  GA+L +DGRDF  +G+EDG+++G CLFD V   M IY+EEIFGPVLSVVRA +YEE L LA+ + YGNG AI+TRDGD AR F  RVN+GMVG+NVPIPVPLAY+TFGGWK+SGFGDLNQHGPDAF+FYTRTKT+TSRWPSG+KEGAEFSIP ME
Sbjct:    4 IPHYIGGKRVEGTSGRSADVFNPATGEVQAQVPLASADELNAAIENAKQAQPAWGATNPQKRARVMMKFVDLLHRDMDKLAEALSREHGKTIPDAKGDVIRGLEVAEYCIGAPQMLKGEFSEGAGPGIDMHSVKQPLGVAAGITPFNFPAMIPMWKFCPAIVCGNAFILKPSERDPSVPLMLAELMSEAGLPDGILNVVHGDKEAVDGILDHPDIMAVGFVGSTPIAEYVYTRGCANGKRVQCFGGAKNHMIIMPDADMDQTVDALIGAGYGAAGERCMAISVAVPVGEDTANRLMEKLAPRVEALKIAPYTAGDDADFGPLVTKEAYTRVKGYIDKG------------------------VEEGADLVIDGRDFSMQGYEDGYFMGACLFDNVTKDMTIYKEEIFGPVLSVVRAKDYEEGLDLAMSHEYGNGVAIFTRDGDAARDFASRVNIGMVGINVPIPVPLAYYTFGGWKRSGFGDLNQHGPDAFKFYTRTKTITSRWPSGIKEGAEFSIPTME 499          

Query:   10 IKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVM 528
            I H +GG  VAGTSGR  DV+NPATG V+ +V LASA+++  AV+ A +AQ AWAA NPQRRARVLMKFV LLNRDMDKLAEALSREHGKTI DAKGDV RGLEVAEFCIGAPHL+KGE+++ AGPGIDLYSMRQPLGV AGITPFNFPAMIPMWKFCPAIAAGN+FILKPSER P+VPMMLAELM+EAGLP G+LNVV+GDK AVDAIL HPDI AVGFVGSTPIA Y+Y++GCAN KRVQCFGGAKNHMIIMPDADL+QAA+ALVGAG+GAAGERCMA+SVAVPVG ETA++L+E L P V+ LK+GPY+AGD +D+GPLVT +A  RV  LV+SG+ A                        GAEL VDGR+F  +G+E+G +IG CLFD+V T MDIY +EIFGPVLSVVRA NYE+A+ L +++ YGNG AI+TRDGD AR FV R+NVGMVGVNVPIPVPLAYHTFGGWK+SGFGDLNQHGPDAFRFYTRTKTVT RWPSG+K+GAEF IP M
Sbjct:    4 IGHFIGGKTVAGTSGRTGDVYNPATGEVDAKVALASAKDLADAVETAKKAQPAWAATNPQRRARVLMKFVDLLNRDMDKLAEALSREHGKTIPDAKGDVIRGLEVAEFCIGAPHLMKGEYSEGAGPGIDLYSMRQPLGVVAGITPFNFPAMIPMWKFCPAIAAGNAFILKPSERDPSVPMMLAELMIEAGLPEGILNVVNGDKEAVDAILDHPDIMAVGFVGSTPIAEYIYARGCANGKRVQCFGGAKNHMIIMPDADLDQAANALVGAGYGAAGERCMAVSVAVPVGEETANRLVEKLAPMVENLKIGPYTAGDDVDFGPLVTKEARERVLGLVNSGLEA------------------------GAELVVDGREFKMQGYENGNFIGGCLFDRVTTDMDIYTQEIFGPVLSVVRAKNYEDAIRLPMEHEYGNGVAIFTRDGDAARDFVSRINVGMVGVNVPIPVPLAYHTFGGWKRSGFGDLNQHGPDAFRFYTRTKTVTQRWPSGIKDGAEFVIPTM 498          

Query:    8 EQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVM 528
            +++ H +GG  V G SGRFADV NPATG V+ +VPLAS EE+  AV  AA+AQ+ WAA NPQ+RARVLMKFV LL+RDMDKLAEALSREHGKTI DAKGD+ RGLEVAEFC GAPHLLKGEFT+ AGPGID+YS+RQPLGV AGITPFNFPAMIPMWKFCPAIAAGN+FILKPSER P+VP+MLAELM EAG P G+LNVV+GDK AVDAIL HP+I A+GFVGSTPIA Y+YS+GCAN KRVQCFGGAKNHMIIMPDAD++QA DALVGAG+GAAGERCMAISVAVPVG +TAD L+E L PRV+ALK+GPY+ GD +D+GPLVT +A  RV  LV+SG                        V  GA+L VDGR+F  +G+E+G+++G CLFD V   MDIY +EIFGPVLSVVRA  Y EAL   +++ YGNGTAIYTRDGDTAR FV R+N+GMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVT+RWPSG+KEGAEFSIP M
Sbjct:    2 QELTHFIGGEHVKGKSGRFADVMNPATGEVQARVPLASNEELAEAVTVAAKAQVGWAATNPQKRARVLMKFVELLHRDMDKLAEALSREHGKTIPDAKGDIIRGLEVAEFCFGAPHLLKGEFTEGAGPGIDMYSLRQPLGVVAGITPFNFPAMIPMWKFCPAIAAGNAFILKPSERDPSVPLMLAELMSEAGAPDGILNVVNGDKGAVDAILDHPEITAIGFVGSTPIAEYIYSRGCANGKRVQCFGGAKNHMIIMPDADMDQAVDALVGAGYGAAGERCMAISVAVPVGEKTADLLIEKLAPRVEALKIGPYTDGDDVDFGPLVTREARDRVLGLVNSG------------------------VEQGAKLVVDGRNFSMQGYENGYFVGGCLFDNVTRDMDIYTQEIFGPVLSVVRAPTYAEALRYPMEHEYGNGTAIYTRDGDTARDFVSRINIGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTARWPSGIKEGAEFSIPTM 498          

Query:    9 QIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVM 528
            ++ H +GG  V G S RFADV NPATG V+ +VPLAS+EE+  AV+ AA+AQ+ W A NPQ+RARVLMKFV LL+RDMDKLAEALSREHGKTI DAKGDV RGLEVAEFC GAPHLLKGEFT+ AGPGID+YS+RQPLGV AGITPFNFPAMIPMWKFCPAIAAGN+FILKPSER P+VP+MLAELM EAGLP G+LNVV+GDK AVDAIL HP+I A+GFVGSTPIA Y+Y +GCAN KRVQCFGGAKNHMIIMPDAD++QA DAL+GAG+GAAGERCMAISVAVPVG +TAD L+E L PRV+ALK+GPY+ G+ +D+GPLVT +A  RV  L++SG                        V  GA+L VDGRDF  +G+EDG+++G CLFD V   MDIY++EIFGPVLSVVRA  Y EAL   +++ YGNGTAI+TRDGDTAR FV R+N+GMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPD FRFYTRTKTVT+RWPSG+KEGAEF IP M
Sbjct:    3 ELTHYIGGKHVKGQSDRFADVMNPATGEVQAKVPLASSEELAHAVEVAAKAQVGWGATNPQKRARVLMKFVQLLHRDMDKLAEALSREHGKTIPDAKGDVIRGLEVAEFCFGAPHLLKGEFTEGAGPGIDMYSLRQPLGVVAGITPFNFPAMIPMWKFCPAIAAGNAFILKPSERDPSVPLMLAELMTEAGLPDGILNVVNGDKGAVDAILDHPEIMAIGFVGSTPIAEYIYGRGCANGKRVQCFGGAKNHMIIMPDADMDQAVDALIGAGYGAAGERCMAISVAVPVGEKTADLLIEKLAPRVEALKIGPYTDGNDVDFGPLVTKEARNRVLGLINSG------------------------VEQGAKLVVDGRDFSMQGYEDGYFVGGCLFDNVTRDMDIYQQEIFGPVLSVVRAPTYAEALRYPMEHEYGNGTAIFTRDGDTARDFVSRINIGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDGFRFYTRTKTVTARWPSGIKEGAEFVIPTM 498          

Query:    6 VSEQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVM 528
            +++QI H + G  VAGTSGR ADV+NPATG V+ +V LAS  E+D A+ NA  AQ  WAA+NPQ+RARV M FV LL+RDMDKLAEALSREHGKT+ DAKGDV RGLEVAEFCIG PH++KGEF++ AGPGID++SM Q LGV AGITPFNFPAMIPMWKFCPAIAAGNSFILKPSER P+VPMMLAELM+EAGLP G+LNVV+GDK AVD IL H DI A+GFVGSTPIA Y+Y++GCAN KRVQCFGGAKNHMIIMPDADL+Q ADAL+GAG+GAAGERCMAISVAVPVG ETAD+LME L PRV+ALK+ PYSAG   D+GPLVT +AL RV+  VD+GV                         AGA+L VDGR+F  +G+E+GF++G CLFD V   M IY+EE+FGPVLSVVRA  YEE L LA+ + YGNG +IYTRDGD AR F  R+N+GMVG+NVPIPVPLAY+TFGGWK+SGFGDLNQHG DAF+FYTRTKTVTSRWPSG+K+GAEFSIP M
Sbjct:    1 MTKQIGHFIDGQHVAGTSGRTADVYNPATGEVQAEVALASQSELDNAIANAKAAQPKWAAINPQKRARVFMNFVQLLHRDMDKLAEALSREHGKTLPDAKGDVIRGLEVAEFCIGTPHMMKGEFSEGAGPGIDMHSMPQALGVVAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERDPSVPMMLAELMVEAGLPNGILNVVNGDKEAVDGILDHQDIEAIGFVGSTPIAEYIYTRGCANGKRVQCFGGAKNHMIIMPDADLDQVADALIGAGYGAAGERCMAISVAVPVGKETADRLMEKLTPRVEALKIAPYSAGSDADFGPLVTKEALARVKGYVDAGV------------------------EAGADLVVDGREFSMQGYENGFFMGACLFDNVTKDMSIYKEEVFGPVLSVVRAKTYEEGLDLAMSHEYGNGVSIYTRDGDAARDFASRINIGMVGINVPIPVPLAYYTFGGWKRSGFGDLNQHGADAFKFYTRTKTVTSRWPSGIKDGAEFSIPTM 499          

Query:    8 EQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVME 529
            +Q+ H + G +V+GTS R AD++NPATG V+ QVPLA+A ++DAAVQ AA+AQ+AW A NPQRRARVLM+FV LL+RDMDKLAEALSREHGKT+ DAKGDV RGLEVAEFC+GAPHLLKGE+TD AGPGID+YSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGN+FILKPSER P+VP+MLAELM EAGLP G+L VV+GDK AVDAIL H  I+AVGFVGSTPIA Y+Y +GCAN KRVQCFGGAKNHMIIMPDAD++QAADAL+GAGFGAAGERCMAISVAVPVG ETADKLM  L P+V+ALK+GPY+ GD +D+GPLVTA+A +RV  LV+SGV                         AGA+L VDGR F  +G+EDGF+ G CLFD V   MDIY +EIFGPVL  VRA+NYE+AL LA+D+ YGNGTAI+TRDGD AR F +R+NVGMVG+NVPIPVPLAYHTFGGWKKS FGDLNQHGPDAFRFYT+TKTVT+RWPSG+K+GAEFSIPVM+
Sbjct:    2 QQLWHFIDGKRVSGTSDRKADIYNPATGEVQAQVPLANAADMDAAVQGAAKAQVAWGATNPQRRARVLMEFVRLLHRDMDKLAEALSREHGKTLPDAKGDVIRGLEVAEFCLGAPHLLKGEYTDGAGPGIDMYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNAFILKPSERDPSVPLMLAELMQEAGLPDGILQVVNGDKEAVDAILDHEGISAVGFVGSTPIAAYIYERGCANGKRVQCFGGAKNHMIIMPDADMDQAADALIGAGFGAAGERCMAISVAVPVGEETADKLMAKLAPKVEALKIGPYTGGDDVDFGPLVTAEAKSRVGGLVESGV------------------------EAGAKLVVDGRGFSMQGYEDGFFFGACLFDHVTPDMDIYTQEIFGPVLVTVRAENYEDALKLAMDHEYGNGTAIFTRDGDAARDFANRINVGMVGINVPIPVPLAYHTFGGWKKSSFGDLNQHGPDAFRFYTKTKTVTARWPSGIKDGAEFSIPVMK 499          

Query:    9 QIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVM 528
            +I H VGG ++ G SGR +D+FNPATG V+ +V LASA+E++AAV+NA  AQ  WAA NPQ+RARV+MKFV LL+RDMDKLAEALSREHGKT+ DAKGDV RGLEVAEFCIGAPHLLKGEF++ AGPGID++S+RQPLGV AGITPFNFPAMIPMWKFCPAIAAGN+FILKPSER P+VPMMLAELM+EAGLPAG+LNVV+GDK AVD IL HPD+ AVGFVGSTPIA YVY++ CAN KR QCFGGAKNHM+I+PDAD++QA DALVGAG+GAAGERCMA+SVAVPVG ETAD+LME L PRV+ LK+ PY+AGD  D+GPLVT +A  RV+  VD G                        V  GA+L VDGRDF  +G+EDG++IG CLFD V   M IY+EEIFGPVLSVVRA  Y+EAL LA+ + YGNG AIYTRDGD AR F  R+NVGMVG+NVPIPVPLAY+TFGGWK+SGFGDLNQHGPDAFRFYT+TKT+TSRWPSG+K+GA+F IP M
Sbjct:    3 KIGHFVGGARIEGMSGRHSDIFNPATGEVQGKVALASADELNAAVENAKAAQPDWAATNPQKRARVMMKFVDLLHRDMDKLAEALSREHGKTLPDAKGDVIRGLEVAEFCIGAPHLLKGEFSEGAGPGIDIHSVRQPLGVVAGITPFNFPAMIPMWKFCPAIAAGNAFILKPSERDPSVPMMLAELMMEAGLPAGILNVVNGDKGAVDGILDHPDVHAVGFVGSTPIAEYVYTRACANGKRAQCFGGAKNHMLILPDADMDQAVDALVGAGYGAAGERCMAVSVAVPVGEETADRLMEKLTPRVENLKIAPYTAGDDADFGPLVTKEAHARVKGYVDKG------------------------VEEGAKLVVDGRDFSMQGYEDGYFIGGCLFDNVTKDMTIYKEEIFGPVLSVVRAKTYDEALDLAMTHEYGNGVAIYTRDGDAARDFASRINVGMVGINVPIPVPLAYYTFGGWKRSGFGDLNQHGPDAFRFYTKTKTITSRWPSGIKDGADFVIPTM 498          

Query:    6 VSEQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVM 528
            +++QI H + G  VAGTSGR ADV+NPATG V+ +V LAS  E+D A+ NA  AQ  WAA NPQ+RARV M FV LL+RDMDKLAEALSREHGKT+ DAKGDV RGLEVAEFCIG PH++KGEF++ AGPGID++SM Q LGV AGITPFNFPAMIPMWKFCPAIAAGN+FILKPSER P+VPMMLAELM+EAGLP G+LNVV+GDK AVD IL H DI A+GFVGSTPIA Y+Y++GCAN KRVQCFGGAKNHMIIMPDADL+Q ADAL+GAG+GAAGERCMAISVAVPVG ETAD+LME L PRV+ALK+ PYSAG   D+GPLVT +AL RV+  VD+GV                         AGA+L VDGR F  +G+EDGF++G CLFD V   M IY+EEIFGPVLSVVRA  YEE L LA+ + YGNG +IYTRDGD AR F  R+N+GMVG+NVPIPVPLAY+TFGGWK+SGFGDLNQHG DAF+FYTRTKTVTSRWPSG+K+GAEFSIP M
Sbjct:    1 MTKQIGHFIDGQHVAGTSGRTADVYNPATGEVQAEVALASQSELDNAIANAKAAQPKWAATNPQKRARVFMNFVQLLHRDMDKLAEALSREHGKTLPDAKGDVIRGLEVAEFCIGTPHMMKGEFSEGAGPGIDMHSMPQALGVVAGITPFNFPAMIPMWKFCPAIAAGNAFILKPSERDPSVPMMLAELMVEAGLPNGILNVVNGDKEAVDGILDHQDIEAIGFVGSTPIAEYIYTRGCANGKRVQCFGGAKNHMIIMPDADLDQVADALIGAGYGAAGERCMAISVAVPVGKETADRLMEKLTPRVEALKIAPYSAGSDADFGPLVTKEALARVKGYVDAGV------------------------EAGADLVVDGRKFSMQGYEDGFFMGACLFDNVTKDMSIYKEEIFGPVLSVVRAKTYEEGLDLAMSHEYGNGVSIYTRDGDAARDFASRINIGMVGINVPIPVPLAYYTFGGWKRSGFGDLNQHGADAFKFYTRTKTVTSRWPSGIKDGAEFSIPTM 499          

Query:    8 EQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVME 529
            E I H + G +  G SG F+DVFNPATG V+ +V LA+  E+D  V+ A  AQ AWAA NPQRRARVLMKFV L++RDMDKLA+ LS EHGKT  DAKGD+ RGLEVAEFC GAPH LKGEFTDSAGPGID+YSMRQPLGV AGITPFNFPAMIPMWKFCPAIAAGN+FILKPSER P+VP+MLAEL+ EAGLP G+L VV+GDK +VD IL++ +I+A+GFVGSTPIA Y+YS+GC+  KRVQCFGGAKNHM+IMPDADL+QA DALVGAG+GAAGERCMAISVAVPVG ETADKL+E LIPRV++LK+GPY++   +D GP+VT +A  R+  L+DSGV                        A GA+L VDGRDF  +G+E+GF++G CLFD V T MDIY++EIFGPVLS VRA NYEEALS+ ++N YGNGTAI+TRDGDTAR F +R+NVGMVGVNVPIPVPLAYHTFGGWKKS FGDLNQHGPDAFRFYTRTKT+TSRWP+G+KEGA FSIP ME
Sbjct:    2 ENIGHFINGKREPGESGNFSDVFNPATGEVQARVSLANKGELDKIVELAKNAQPAWAATNPQRRARVLMKFVELIHRDMDKLAKKLSSEHGKTFPDAKGDIIRGLEVAEFCFGAPHFLKGEFTDSAGPGIDMYSMRQPLGVVAGITPFNFPAMIPMWKFCPAIAAGNAFILKPSERDPSVPIMLAELLTEAGLPDGILQVVNGDKVSVDGILENLNISAIGFVGSTPIAEYIYSKGCSFGKRVQCFGGAKNHMLIMPDADLDQAVDALVGAGYGAAGERCMAISVAVPVGKETADKLVEKLIPRVESLKIGPYTSDTEMDLGPVVTREAKNRILGLIDSGV------------------------AQGADLKVDGRDFKLQGYENGFFVGACLFDNVTTEMDIYKQEIFGPVLSTVRAQNYEEALSIVVNNEYGNGTAIFTRDGDTARDFSNRINVGMVGVNVPIPVPLAYHTFGGWKKSAFGDLNQHGPDAFRFYTRTKTITSRWPTGIKEGASFSIPTME 499          

Query:    8 EQIKHLVGGVQVAGTSGRFADVFNPATGAVERQVPLASAEEVDAAVQNAAQAQLAWAAVNPQRRARVLMKFVTLLNRDMDKLAEALSREHGKTIADAKGDVQRGLEVAEFCIGAPHLLKGEFTDSAGPGIDLYSMRQPLGVAAGITPFNFPAMIPMWKFCPAIAAGNSFILKPSERAPTVPMMLAELMLEAGLPAGVLNVVHGDKTAVDAILQHPDIAAVGFVGSTPIARYVYSQGCANDKRVQCFGGAKNHMIIMPDADLEQAADALVGAGFGAAGERCMAISVAVPVGAETADKLMELLIPRVQALKVGPYSAGDSIDYGPLVTADALTRVRSLVDSGVAAGAELAVDADALTRVRSLVDSGVAAGAELAVDGRDFVCEGFEDGFYIGPCLFDKVDTSMDIYREEIFGPVLSVVRADNYEEALSLAIDNPYGNGTAIYTRDGDTARSFVHRVNVGMVGVNVPIPVPLAYHTFGGWKKSGFGDLNQHGPDAFRFYTRTKTVTSRWPSGVKEGAEFSIPVME 529
            E I H + G +  G SG F+DVFNPATG V+ +V LA+  E+D  V+ A  AQ AWAA NPQRRARVLMKFV L++RDMDKLA+ LS EHGKT  DAKGD+ RGLEVAEFC GAPH LKGEFTDSAGPGID+YSMR PLGV AGITPFNFPAMIPMWKFCPAIAAGN+FILKPSER P+VP+MLAEL+ EAGLP G+L VV+GDK +VD IL++ +I+A+GFVGSTPIA Y+YS+GC+  KRVQCFGGAKNHM+IMPDADL+QA DALVGAG+GAAGERCMAISVAVPVG ETADKL+E LIPRV++LK+GPY++   +D GP+VT +A  R+  L+DSGV                        A GA+L VDGRDF  +G+E+GF++G CLFD V T MDIY++EIFGPVLS VRA NYEEALS+ ++N YGNGTAI+TRDGDTAR F +R+NVGMVGVNVPIPVPLAYHTFGGWKKS FGDLNQHGPDAFRFYTRTKT+TSRWP+G+KEGA FSIP ME
Sbjct:    2 ENIGHFINGKREPGESGNFSDVFNPATGEVQARVSLANKNELDKIVELAKNAQPAWAATNPQRRARVLMKFVELIHRDMDKLAKKLSSEHGKTFPDAKGDIIRGLEVAEFCFGAPHFLKGEFTDSAGPGIDMYSMRXPLGVVAGITPFNFPAMIPMWKFCPAIAAGNAFILKPSERDPSVPIMLAELLTEAGLPDGILQVVNGDKVSVDGILENLNISAIGFVGSTPIAEYIYSKGCSFGKRVQCFGGAKNHMLIMPDADLDQAVDALVGAGYGAAGERCMAISVAVPVGKETADKLVEKLIPRVESLKIGPYTSDTEMDLGPVVTREAKNRILGLIDSGV------------------------AQGADLKVDGRDFKLQGYENGFFVGACLFDNVTTEMDIYKQEIFGPVLSTVRAKNYEEALSIVVNNEYGNGTAIFTRDGDTARDFSNRINVGMVGVNVPIPVPLAYHTFGGWKKSAFGDLNQHGPDAFRFYTRTKTITSRWPTGIKEGASFSIPTME 499