Query:    4 MSYPLYLAIFM-QLILVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMS--QNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNL---NHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLD-PMVSDPLLPQKPEQILQSGHYEK-VPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIF-----QWTPTQAPAMRFATIGSDMIMSDVPAYWERVEFFHRI 586
            M + L++ + M Q+ + ++L+   P+      ED  I+  + G VRG    S  QN K YA + GLPYA PP+GE RF RP+P   +W+ IRD T+ PPIC Q ++   N   T G EDCLV+N+ QP TC   + C V++W+H G +A + GSP TF P  +MDH ++ + +NYRLG +GFL+LE + APGNLGLRDQ+LA+KWI+ EI    G+ D+ITL+G G+G  SA++H++SP N  +  F  +I+QSGSP ED  L FA+S++ YA ++A S+GC+K     +LKCL+S  AD +Q K+  F+  + +F PNP+VP +D     DP+LP  PE I+++ ++ + +PI+ G  + EG+ LM +F  HP ++A FT +LP L+ N   +  T    DLVE+VK+ ++   ++     +  I +FTD  F G+IGR  QLL+   +  P++QYI++Y GTHSFGD+S Y+ +KL  KL L S GIG  MRNG+G CHGDELF +FK+G L APM  GP S+ DK V  +++  W NFA+TG P+ P   F     +W   Q      A I +   M +     +RV F+HR+
Sbjct:    1 MEFSLHIVLIMIQVAIAILLYFIFPVHSKIPIEDS-ILHLTKGDVRGIIQYSPLQN-KPYASYFGLPYALPPLGERRFARPEPYSNAWEGIRDGTQSPPICVQQDIHRNNPNDTIGVEDCLVLNINQPLTCTRENRCPVIIWLHGGSYALLSGSPYTFNPLYFMDHNVIFIGINYRLGAMGFLTLETDEAPGNLGLRDQSLAIKWIRDEIDNLYGNKDQITLMGHGSGAHSALIHLVSPFN-KKGTFTRIITQSGSPFEDTNLRFAKSRKEYAKKLAASVGCTK----EILKCLRSRPADILQTKVQTFNIINQVFTPNPWVPVIDIKFAHDPVLPDYPENIVKNTNFSRSIPILTGSVAEEGMLLMKRFFQHPELFAQFTRTLPFLLFNLEDESVTPKVQDLVEIVKKFFIPKGQLSYSQNKQIIAMFTDMVFYGKIGRAIQLLR---DHGPIYQYIYKYFGTHSFGDLSFYSDFKLGLKLSLQSRGIGLFMRNGFGTCHGDELFDIFKIGFLKAPMSSGPISDFDKSVGQSLITMWINFARTGNPT-PMGYFLDDNSKWLSIQESNGMVAEIKTKTRMIEDTFLEKRVNFYHRV 585          

Query:   34 FEDPPIIQTSHGKVRG-KNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCL-QSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEG---IALMGQFLAHPGMYANFTE-SLPLL---MLNRASQETTEGDTDLVEVVKRAY-----LDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPN-GPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAP-MGLGPTSERDKRVSGNILR-TWTNFAKTGTPSRPS--DI-FQWTPTQAPAMRFATIGSDMIMS-----DVPAYWER 579
            F +  I++TS G + G +   S NG  Y+ F G+ YA PPV +LRFK P   +  W    +A +   IC Q ++ ++   G EDCL +NVY P   +     AVMV IH G F    G    FGP   M++ IV+V+ NYRLG LGFL+ ++     N G++DQ +ALKW+K+ I  FGGDP+++T+IG  AG +SA +  +SP    Q LF GVI+ SG+ + D+ ++   +    A E+A  L CS T  + +++C+ +  + D ++K  +M     F   P  F P++D      +LP +PE +L +G + KVPI++G   + G     L      + G   NF +  LP L   M N  S+        +   +++ Y     ++ +  FR      I+  TD  F      T +  +++ N   P ++Y+F Y G +S  +                  G   +M    GV HGDE+  +F   N+      + P    D + + NI     ++FAKT  P+ P+  DI   W+P      R   I + + M+     D+  +W  
Sbjct:   17 FGEDMIVKTSKGPIMGLREDSSSNGYFYS-FKGIRYAMPPVEDLRFKAPT-ELEPWTETVEAVEDGHICPQYDIANSIPLGDEDCLFLNVYTPKIDS--KKRAVMVHIHGGAFILGGGVSHLFGPDYLMENDIVLVNFNYRLGALGFLTTKDTMETANNGIKDQIMALKWVKENIDKFGGDPNKVTIIGEDAGAASATILSMSP--AAQGLFQGVIALSGNALCDQFIQ--NNPDEAAKELAARLECSSTDGKDIIECISRKTQQDIVEKSNSMMM---FYTFPRWFAPNVD----GDILPDRPENLLSNGQFSKVPIVLGQTKNGGAFYYRLTINSFNNGGYDDNFIDHKLPRLLPVMTNYNSKLYP-----ITRSIRKRYFVNVDMENEDEFR---PRYIEFLTDMLFTKC---TDEFARAIANHSVPTYEYLFDYRGQYSIVNFQ----------------GEQVDM----GVVHGDEMQYVFH--NIWGEDFSMSPA---DLKFTKNIFTPLLSSFAKTSVPTLPTIDDINVSWSPRAPNKNRILKISNKLEMNEDYKKDILKFWNE 536          

Query:   26 LPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQ-LNLNHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKR--AYALEVAGSLGC--SKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLP----NPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESL----PLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFG--DISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTP----SRPSDIFQWTPTQAPAMRFATIGSDMIMSDVPAYWERVEFFHRI 586
            + + G  +F   P+  T  G + G    ++ G     F G+ + RPPVG+LRFK P P    W  IR+A K    C Q +        G+EDCL +NV+     A      V+VWIH G F  + G    + P   +D  IV+V++ YRLG+ GFLS E++ APGN G+ DQ  AL+W+K  I AF GD + IT++G  AGG+S   HMLS  ++++ LFH  IS SGS +      +A  KR    A ++A  L C     K + +++C++ +E + +      F E   L       N + P +DP  +   +P +P  ++ +G+++ VP I G    EG      F +       F E      PL+      Q  +E    +   V   Y + K++ + N +  +   +  S+   +   ++ +QS+ +  PV+ Y F Y G +S    D + + P  ++  +              YGV +GD+L  +F     +      P    D   S   ++ +T+FA  G P        D F W P          IG++M M       ER+ F+  +
Sbjct:   78 IKVQGKWEF---PVAITKSGMLWGTIEETRTGGRILAFRGIRHVRPPVGDLRFKAPVP-FPRWDGIREAKKNGHFCPQHMYYKPDVWIGEEDCLWLNVFS-RDLAVNKKRPVIVWIHGGNF--VRGXAADYEPDYLLDEDIVLVTIQYRLGMFGFLSSEDQYAPGNYGMLDQVAALQWVKTNIDAFSGDVNHITIMGQQAGGASVHYHMLS--SLSRGLFHRAISLSGSALS----WWASLKRPLERAKKLARLLECPYDADKSKEMIECIRGIEMEKMMNTHPNFYEWKHLNQNQEPVNAWSPRVDPEAALSFMPNEPIDLMTAGNFQHVPWIAGITDDEGAFKGSAFFSEMRNVREFEEDFEKIGPLMFGFHDGQ--SEAPKMMARKVMDYYWNGKELTKENAKSLVDALSXSSYAHPVDXASK-IQSIKSQAPVYVYHFGYKGVNSLTQMDTNSHPPQVIQRDI-------------PYGVGNGDDLIYLFP----ILSGAFRPLPHDDLIFSQRFIQLFTSFATDGKPVIKMGEGIDDFVWHPVDPNNATHLDIGNEMRMDLGLPNHERMNFWQSM 624          

Query:   14 MQLILVLILFNFLPISGAKQFED----PPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKP-PPICSQLNLNHTGT-----TGQEDCLVVNVYQPATCA----PLSPCA------VMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIED--KQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESL-----PLLMLNRASQETTEGDTDLVEVVKRAYLDTKK-IFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDI---SVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKL--GNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIFQWTPT 554
              + L   L     I G ++F D    P I+ +  G V+G        K +  F G+PYA PP GE RF+ P+P    WK    A +  PP C Q   ++  +      G EDCL +N++ P + +      SP +      VMVWIH G F  M G+   +    +M   I++V ++YRLG LGFL+L  E A GN G+ DQ LAL WI+  IS+FGGDP R+T+ G  +G  S + HM  P  +++ LF   I QSGS  +   K+        A+  E+ G +G   T+     +C+Q +    I  K    S+ +     +PF     P++    L ++     +  H  +V  ++G  S+EG     +F+    +  N+TE           LN A  E+     DL  V+   +   KK  F   +Q+   L +DF + G    T + + +   G PV+ Y++ + G  S  D    + Y  WK     F+  +  G       G  H DEL  +F+    NLL      P  E+  R+   ++  WTNFA +G P+   + + W P 
Sbjct:    7 FNIYLYFSLLTLFSIYGPEKFFDEFWSPLIVHSPSGLVQGARE-----KGHQAFYGIPYALPPTGERRFRSPEPYPTPWKRTLQAGRSYPPACPQQLRSYFKSLLWDVEGNEDCLYLNIFSPDSASLQLSNESPPSQENLFPVMVWIHGGNF--MSGTASDYESIYFMTKDIILVMISYRLGPLGFLNLGEEYARGNQGIEDQILALSWIQDNISSFGGDPQRVTIFGESSGAISVLHHMSVP--MSKLLFQSAIIQSGSIYQPTIKETFMMEMHEAWIAEM-GCIGVIDTQ-----ECIQKLPLAKIVNKNPFLSDCNLKKNGHPFPNPWFPVLEGSYLLKEVSAENKKSHAPRV--MIGTTSNEGFLATSRFM----LQNNYTEGFMSKWEECFKLNTAGDES----YDLEPVMDYYFGSNKKPDFPSQVQNFSNLISDFWYNGPTFETVKEIAN--KGSPVYYYLYDHDGFLSMTDSLSRASYDYWK-----FIVRYAFGQESGKTNGASHADELPFLFREYPRNLLK----RPVDEKMWRL---MIDVWTNFATSGDPNGAKEGYNWKPV 541          

Query:   10 LAIFMQLILVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQL-----------NLNHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWM-DHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSP-----IEDKQLEFARSKRAYALEVAGSLGC--SKTKMEHVLKCLQSVEADAI--QKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFR-----------------LNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKR---VSGNILRTWTNFAKTGTPSRPSD 547
              ++   ILV +L   L  S     +D  +I T  GK+RG    S   +    + G+PYA+PPVG LRF+ P+  I +W+ I++ T+PP  C Q+            + +  T   EDCL ++V+ P      S  AV+VWI+ G F     + + + P++ + +  I+ V++ YR+  LGFL  + E  PGN GL DQ +AL+W+K  I  FGGDPD+IT+ G  AGG S  LH+LSP  ++++LF   I QS S      +  K+    R +R     +A  + C   +   + +++CL+  +A  +  Q+ + + S         PFV    P+V    L + P + L + +Y+K  I++G N  EG   +  +L    ++ N TES   + ++R         TD +  V       KK+ R                  N +   ++  D+ F+       ++  S  N   V+ Y F    + S        PW                     GV HGDE+  +F          L  +   DK    +S  ++  W NFAKTG PS  +D
Sbjct:   10 FGLYFNKILVYLLT--LSWSVGAIVQDNLVITTKKGKIRGVTLKSATNREVDAWYGIPYAQPPVGNLRFRHPR-HIDAWEGIKETTRPPNSCIQVVDTLFPGFEGAEMWNVNTEPSEDCLYLSVHVPKPRPTGS--AVLVWIYGGGFYSGTSTLEVYDPRVLVSEENIIFVAMQYRVASLGFLFFDTEDVPGNAGLYDQMMALQWVKNNIEEFGGDPDKITIFGEXAGGCSVALHLLSP--LSRNLFSQAIMQSASALVPWGVITKKESIIRGRR-----LAEMMSCPYDEKNTKAMIECLRQKDATEMVNQEWIGIISG----IAEFPFV----PIVDGSFLDESPGKSLTTKNYKKTNILIGANKEEGNYFIMYYLTD--LFKN-TES---VYVDR---------TDFIRSVSELNHYVKKMGREAITFEYTDWLNPNDPIKNREAIDRMVGDYQFICPTADFARIYASTGNN--VYMYYFTERSSTS--------PWP-----------------TWSGVLHGDEIAFVFG-------EALNKSKNYDKSEIALSKRMMGYWANFAKTGNPSLSAD 519          

Query:   10 LAIFMQLILVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQL-----------NLNHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWM-DHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSP-----IEDKQLEFARSKRA-------YAL----------------EVAGSLGC--SKTKMEHVLKCLQSVEADAIQKKL---TMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFL-----AHPGMYANFTE------SLPLLMLNRASQETTEGDTDLVE----VVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPT-SERDKRVSGNILRTWTNFAKTGTPS 543
            L +  + ILV +L   L  S     ++  +I T  GK+RG    S   K    + G+PYA+PPVG LRF+ P+  I +W  +++ TK P  C Q+            + +T T   EDCL ++V+ P      S  AV+VWI+ G F     + + + P++ + +  I+ V + YR+  LGFL  + E  PGN GL DQ +AL+W+K  I AFGGDPD+IT+ G  AGG S  LH+LSP  +++ LF   I QS S      +  K+    R +R        YAL                 +A  + C   +     +++CL   +A  +  +    T+F  ++F     PFVP +D    D    + PE+ L+   Y+K  I+MG N  EG   +  +L      +  +Y N T+       L + + N   +  T   TD +     +  R  +D             ++  D+ F        ++  S  N   ++ Y F    + S        PW                     GV HGDE+  +F       P+       + +  +S  I+  W NFAKTG P+
Sbjct:   10 LGLSFERILVYLLT--LSWSLGSIVQEDLVITTRKGKIRGVTLKSATNKEVDAWYGIPYAQPPVGNLRFRHPK-DINAWDGMKETTKHPNSCIQVVDTFFPGFEGSEMWNTNTEQSEDCLYLSVHAPKPRPTKS--AVLVWIYGGGFYSGTSTLELYDPRVLVSEENIIFVGIQYRVASLGFLFFDTEDVPGNAGLYDQMMALQWVKNNIEAFGGDPDKITIFGEXAGGCSVALHLLSP--LSRXLFSXAIMQSSSALVPWGVISKKESIRRGRRLAEEMRCPYALVPWGVISKKESIRRGRRLAEEMRCPYGENNTNAMIECLLQKDATELVNQEGSGTVFGISEF-----PFVPIVDGKFMD----KTPEKSLKEKDYKKTNILMGVNKDEGNFFIMYYLPELFKKNENVYINRTDFIRSVSDLNIYVNNAGREAITFEYTDWLNPNDPIKNREAID-------------RMVGDYQFTCPTADFARIYASTGNN--IYMYYFTERSSTS--------PWP-----------------TWSGVLHGDEIAFVFG-----EPLNTSKNYDDSEIALSKRIMSYWANFAKTGNPN 543          

Query:   86 ASWKNIRDATKPPPICSQLNLNHTGTT---GQEDCLVVNVYQPA--TCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHG-IVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPG----MYANFTESLPLLMLNRASQETT-EGDTDLVEVVKRAYLDTKKIFRL-NMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGP--PVFQYIFRYSGTH-SFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPS 546
             SW+  RDA+ P P   Q   N+ G +   G+EDCL +NVY P            V+VWI+ G + + D S + + P+  ++ G +V+V+LNYRLG LGFL+L NE  PGN+GL DQ LA++WI+  I  FGGD D ITL+G  AG      HM+S  +    LFH  I  SG+ + +K          ++ +V+     +  K E   +C +S            FSE+                           + +++G + K+PI+MG + H GIAL+ + +        +  ++T     L+LNR       + D   V  +K+ Y D ++          I    D  FLG        +++V  G   P++ Y F +  ++ S GD+   +  +L  KLFL   GI        G+ H DELF +F  GN         +++ D++V+        NFA +G P+  S
Sbjct:    3 GSWEGTRDASSPCPKPVQFIPNYGGISSVIGEEDCLYLNVYTPDLPVTENQKKFPVIVWIYGGNYLWGDASERFYFPKYLIESGSVVIVTLNYRLGPLGFLTLGNETVPGNMGLWDQRLAMEWIRTHIGNFGGDADEITLMGHDAGSVCITNHMVSKSSA--GLFHKAICMSGTFVSEK----------FSFDVSDPASLNSIKEEFAKECDKS-----------FFSESQL-------------------------ETIKTGEFNKMPILMGTSRHSGIALISEAIGSEDNKDRLRRDWTVLGGELILNRPENILRPQEDLQFVNTLKKFYFDQEEFTEDGGFDQLINAVGDAVFLGA---NDYFIKAVHGGSAQPIYLYNFDHMYSNISGGDVFSLSTIQLILKLFLSKIGIKMFNDKRPGISHWDELFCIFS-GNDSFLFKHSISNQVDQKVANIFTSFIINFASSGNPTSSS 426          

Query:   40 IQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATK-------PPPICSQLNLNHTGTTGQEDCLVVNVYQPATCA-PLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMD-HGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTK-MEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVSDP---LLPQKPEQILQSGHYEKV-PIIMGGNSHEGIALMGQFLAHPGMYA----NFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRL-----NMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSF 462
            + TS GK++GK  +  +  +Y+ F G+PYA  P    RF   +P  + W    D TK       P P+  +    + G    +DCL +NV+ P           V+V+ H G F       K +GP++ +    +V+V++N+RLG  GFLS +N   PGN G+ DQ L+L W++  I  FGG    +T++G  AGG S++ H+ SP  +++ LFH +I  SG+ +    +   R    YA   A SLG +  + ++++L  L+S+ A  I  K  +F ++ FL    P+ P +D     P    LP     ++  G    V  I+MG  + +G++ + + + +P ++     ++++  P+L  NR     TE D   VE +   +   + +  L     N    +++ T FSF      T +LL    N     QYI ++  +  F
Sbjct:   17 VITSLGKLKGKTLLMNDKHIYS-FTGVPYADKPQ---RFSLAKPC-SKWTGTLDCTKESKMGYQPNPMFFESTFLYHGFP--DDCLYLNVFTPILKEDSFDLLPVIVYFHGGAFILGGNDTKIYGPEILLSTQNMVLVTVNFRLGPFGFLSFQNSDCPGNQGMHDQILSLMWVQSHIHHFGGTSSNVTIMGQXAGGMSSLYHLASP--LSKGLFHKIICLSGAVMYAPFVHIDRDPWDYAKAFAESLGVNVNQSVDNILTQLRSISAKTILSKTFLF-KDVFLLASCPWKPCVDGGYLTPETSFLPDTFINLVSQGKGNPVESILMGYTAQDGLSSLIEVMRYPNIWGLIQKDWSQIAPILFFNRERDNVTEEDRTAVEKMHSMFYGEEVVRPLEWNKKNFSTLVKMATMFSFKLPFYATAKLLHRSVN-----QYIIQWLSSVRF 447          

Query:  200 LKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLD-PMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPG-----MYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIF--RLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIFQWTP-TQAPAMRFATIG--SDMIMSDVPAYW-ERVEFFHRITSQVGLKPEGLDL 599
            L  +K   S    D + IT+ G+ AGG S +  M++   V   LFH  ISQS   I+   +    +   Y+L  +  +GC       + KCL+  +   +  K  MF +  F+  P P+ P +D    S PL       +++ G +  VP++MGG S EG     +F  +       +  NF  +   L++     + T+ D+  V ++   YLD+  I     N+   +++ TD  FLG I +  QL  +  +GP +F Y +RY G+HS           +K          G ++    G  HGDELFL+FK+ ++         S  DK++S  ++  WT+FA  G+P+      +WTP + A A ++  +   S  I++   +Y+ ER+ F       +       DL
Sbjct:   17 LNGLKSISSLLVXDENSITIFGSSAGGISVLTLMMAAHKV-PGLFHKXISQSTPMIDAPFMHLTHNPSYYSLLFSNEMGCDSENSIDISKCLKEKDVYELINKQDMFEK--FMNFPYPWKPVVDFEYASKPLFSMGFVDLIKHGLFTNVPLLMGGTSEEGAMFSPEFFKNDEEKFQELNENFDITGATLLMGIDEADVTDEDSATVNIINIEYLDSDNITYSSENILKLVKMLTDVHFLGPIDKQVQLFANSSHGP-IFYYNYRYKGSHSTS---------IK----------GLDL----GASHGDELFLLFKIQDI-------SLSTEDKKMSDLLIDYWTSFAIHGSPNS-----KWTPVSNAVAPKYVILNNPSSTIVAKRESYFNERMAFISSTXXXIIKSYRNFDL 389          

Query:  115 EDCLVVNVYQPATCAPLSPCA--VMVWIHPGEFAFMDGSP-KTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEH-----VLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSL-------DPMVSDPLLPQKPEQILQSGHYE-KVPIIMGGNSHEGI 359
            EDCL + +  P    P       VM ++H G   F  G+   +   +L     +++V++NYR+G+LGFL L+++ + GN G+ D  LAL+W+++ I  FGGD +R+T+ G  AG ++    +LSP    ++LF   I QSGS I      F R  R    E A  LGC KT  E+     ++KCL++ E   I K+ ++F+          F  S        D     P     P +IL SG Y  +VPI  G N +EGI
Sbjct:  190 EDCLHLTISTPVKPPPKESKGYPVMFFVHGG--GFSSGTHLHSEADRLGDAADVIVVAINYRVGILGFLCLDSDESAGNQGMLDILLALEWVQKYIEHFGGDKERVTIFGESAGSATIGHLLLSPSTREKNLFKYGIGQSGSAI--SPWAFDREPRRSGYEFAERLGC-KTINENEDDDSIVKCLRNFEDWEITKEFSLFTTERRKHFDLGFGGSSPCAQTKGDKKFYGP--KDDPMEILYSGDYNTEVPIFFGNNLYEGI 443          

Query:   14 MQLILVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTG----TTGQEDCLVVNVYQPA--TCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRA--YALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLF-LPNPFVPSLDPMV----SDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFT---ESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTP 542
            ++L  +L+   F+  S   Q +  P + T  G +RG    S++ +LY  + G+PYA+ PVG+ RF+ P+P I  W     ATK   +C Q  +  T       G EDCL +N+Y P      PL P  VM WIH G F F  G+       L+MD  IV V++NYRLG  GFLS  +   PGN+GL+DQ++AL+W+   I +FGG+P++IT+ G  AGG+S   H LSP  ++  LF   IS SG         +A++K A   A ++   + C     + ++ CLQS  A  I + +      DF+F L NPF P   P+V    S+P +   P  I+ +G    VP I G  S EG+    +F+ +  +  +     + +   +L+       +    + + +K  YL +  I    ++  IQ+ +D  F     +  + LQ+  N  PV+ Y + Y   HS  +I                  +       YGVCHGD++FL   L ++++ +    T  +D  +   ++  +T+FA  G P
Sbjct:    4 LKLSYILLFLGFVKFSW--QDKQVPKVSTFTGNIRGYYKKSRSDRLYEAYEGIPYAQSPVGKFRFQPPRP-IKKWSKDLSATKKSSVCMQYLMTFTTHGNRVKGSEDCLYINIYVPVRNNRKPLLP--VMFWIHGGAFQFASGNEAN--ETLFMDRNIVFVAINYRLGPFGFLSTGDIVVPGNMGLKDQSMALRWVFNNIKSFGGNPNKITIFGMSAGGASVHYHYLSP--MSAGLFKRGISISGVAF----CPWAQTKHAPEKAKKLGALMKCRTDNTKKMIDCLQSRPARIIAQAV-----GDFMFWLYNPFTP-FGPVVETYGSNPFISNSPINIINNGQVYDVPWISGVVSKEGLYTAAEFVDNAKLLWHLNDHWDEIAPYLLDFNYTIPLDQHRQVAKKIKNYYLRSGPINYDKVESIIQMMSDRLFNIDFEKAVR-LQARINKSPVWTYYYSYRAEHSVSEI------------------LSGGSTTDYGVCHGDDIFLT--LNSIISNV----TKPQDLAMQQLLINFYTSFAIQGIP 504          

Query:   18 LVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNH-TGTTGQEDCLVVNVYQPATCAPLSP---CAVMVWIHPGEFAFMDGSPKTFGPQLWMDHG-IVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIED-KQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKK-LTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGI---ALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPS------------RPSDIFQWT 552
            ++L LF F+         + P +Q   G++ G    + NG+    FLG+PYA PPV   RFK PQP +  W  + +AT P   C  +     +   GQEDCL +NVY P      S      V+V IH G + F +G    +GP   +D+   V VS+NYRLGVLGF S  +   PGN GL+DQ  ALKWI+Q I AFGGDP+ +T+ G  AG SS   H++SP  +++ LF+  I QSGS        E    K  Y   +A  LGC       +++CL+S  A AI K  L      +F F   PF P+++    +  LP  PE+++       +P+++     EG+     +G       +  N+ E LP ++    +           + +K  Y   K I +    +  ++ +D SF     +  Q + +  N  PV+ Y F YSG +S+  ++ + P                +   G    HGDE   + K+            +E D+++   ++  W  F K+G P              P+D+F++T
Sbjct:    7 ILLNLFLFIGCFLTCSASNTPKVQVHSGEIAGGFEYTYNGRKIYSFLGIPYASPPVQNNRFKEPQP-VQPWLGVWNATVPGSACLGIEFGSGSKIIGQEDCLFLNVYTPKLPQENSAGDLMNVIVHIHGGGYYFGEGI--LYGPHYLLDNNDFVYVSINYRLGVLGFASTGDGVLPGNNGLKDQVAALKWIQQNIVAFGGDPNSVTITGMSAGASSVHNHLISP--MSKGLFNRAIIQSGSAFCHWSTAENVAQKTKY---IANLLGCPTNNSVEIVECLRSRPAKAIAKSYLNFMPWRNFPF--TPFGPTVEVAGYEKFLPDIPEKLVP----HDIPVLISIAQDEGLIFSTFLGLENGFNELNNNWNEHLPHILDYNYTISNENLRFKTAQDIKEFYFGDKPISKETKSNLSKMISDRSFGYGTSKAAQHI-AAKNTAPVYFYEFGYSGNYSY--VAFFDP---------------KSYSRGSSPTHGDETNYVLKVDGFTV-----YDNEEDRKMIKTMVNIWATFIKSGVPDTENSEIWLPVSKNPADLFRFT 526          

Query:   18 LVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNH-TGTTGQEDCLVVNVYQPATCAPLSP---CAVMVWIHPGEFAFMDGSPKTFGPQLWMDHG-IVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIED-KQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKK-LTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGI---ALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTP-SRPSDIFQWTPTQ---APAMRFATI 564
            ++L LF F+         + P +Q   G++ G    + NG+    FLG+PYA PPV   RFK PQP +  W  + +AT P   C  +     +   GQEDCL +NVY P      S      V+V IH G + F +G    +GP   +D+   V VS+NYRLGVLGF S  +    GN GL+DQ  ALKWI+Q I AFGGDP+ +T+ G  AG SS   H++SP  +++ LF+  I QSGS        E    K  Y   +A  +GC       +++CL+S  A AI K  L      +F F   PF P+++    +  LP  PE+++       +P+++     EG+     +G       +  N+ E LP ++    +           + +K  Y   K I +    +  ++ +D SF     +  Q + +  N  PV+ Y F YSG +S+  ++ + P                +   G    HGDE   + K+            +E D+++   ++  W  F K+G P +  S+I  W P     A   RF  I
Sbjct:    7 ILLNLFLFIGCFLTCSASNTPKVQVHSGEIAGGFEYTYNGRKIYSFLGIPYASPPVQNNRFKEPQP-VQPWLGVWNATVPGSACLGIEFGSGSKIIGQEDCLFLNVYTPKLPQENSAGDLMNVIVHIHGGGYYFGEGI--LYGPHYLLDNNDFVYVSINYRLGVLGFASTGDGVLTGNNGLKDQVAALKWIQQNIVAFGGDPNSVTITGMSAGASSVHNHLISP--MSKGLFNRAIIQSGSAFCHWSTAENVAQKTKY---IANLMGCPTNNSVEIVECLRSRPAKAIAKSYLNFMPWRNFPF--TPFGPTVEVAGYEKFLPDIPEKLVP----HDIPVLISIAQDEGLIFSTFLGLENGFNELNNNWNEHLPHILDYNYTISNENLRFKTAQDIKEFYFGDKPISKETKSNLSKMISDRSFGYGTSKAAQHI-AAKNTAPVYFYEFGYSGNYSY--VAFFDP---------------KSYSRGSSPTHGDETSYVLKMDGFYV-----YDNEEDRKMIKTMVNIWATFIKSGVPDTENSEI--WLPVSKNLADPFRFTKI 528          

Query:    3 NMSYPLYLAIFMQLILVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLN-----HTGTTGQ-------EDCLVVNVYQP--ATCAPLSPCAVMVWIHPGEFAFMDGSPKTF-GPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADA---IQKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLM---LNRASQETTEGDTDL-------------VEVVKRAYLDTK------KIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPS 543
            NM + L L++ + L++   L       GA   ++P +I T HG ++GK     +  +   FLG+P+++PPVG  RF  P+P +  W  IRDAT  PP C Q +       +  T  Q       EDCL +NVY P  A  APL P  VMVW   G  AF+ GS  T+ G +L     +V+V L YRLG+LGF S  N  A GN GL DQ  AL+W+++ I AFGGDPD +TL G  AG  S    M+SP  + Q LFH  ISQSG+ +    +         A ++A   GC     + +++CL+S+ A+    + K+++ F  N     P   V  L P+V   + P+ P  +L  G  + VP ++G N+                 A F  +LP LM   LN+     T  +  L             V VV R YL+        K+FR  +   I L  D +F+    +  +  +    G PV+ Y F+                        H    G  ++   G  HGDEL  +F      +P   G ++  +K  S  +++ W NFA TG P+
Sbjct:    7 NMKWILGLSLTLCLVVQTAL-------GALHTKEPLLI-TKHGILQGKQVHVGDTPIQV-FLGIPFSKPPVGTRRFAPPEPPLP-WNGIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAPLLP--VMVWFPGG--AFLAGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSP--LAQGLFHQAISQSGTAVLKAFI--TPDPLTSAKKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKD-PKEIVWFLSPVVDGVVFPEDPVVLLTRGQVKPVPYLLGVNN-----------------AEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNITKEQVPVVAREYLNDAISNHDWKMFRNRL---IDLIGDATFVYATLQAARYHRDA--GSPVYLYEFK------------------------HHASSGIIIKPYNGADHGDELSYLFG-----SPFSKGSSAGEEKEFSLQMMKYWANFAHTGNPN 517          

Query:   35 EDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHT------------GTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGS-PKTFGPQLWMDHGIVMVSLNYRLGVLGFLSL-ENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKF-----KLFLHSFGIGYNMRNG-------YGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRV-SGNILRTWTNFAKTGTPS-RPSDIFQWTPTQAPAMRFATIGSD 567
            E+  II T +GKVRG N     G + A FLG+PYA+PP+G LRFK+PQ S+  W NI +ATK    C Q N + +             T   EDCL +NV+ PA         VM+WI+ G F     S P   G  L     +++VS+NYR+G LGFL+L EN  APGN+GL DQ LAL+W+++ I+AFGG+P  +TL G  AG +S  LH+LSP+  +Q LF   I QSGS      +      R   L +A  +GCS+     ++KCL+  +   I          D L   N       P V    L   P+ +LQ G +++  I++G N  EG A +      PG   +                                 +   I R   Q G+++F  F  + + GR + L   +          +R +     GD ++  P  L+F     +L   +F   +  R+         GV HG E+  +F L     P+       R + + S +I++ W NFAK G P+   ++  +W   ++   ++ T+ ++
Sbjct:    1 EEDIIITTKNGKVRGMNLPVLGGTVTA-FLGIPYAQPPLGRLRFKKPQ-SLTKWSNIWNATKYANSCYQ-NTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKP--KNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPR--SQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVN-----FGPTVDGDFLTDMPDTLLQLGQFKRTQILVGVNKDEGTAFL--VYGAPGFSKD---------------------------------NNSIITRKEFQEGLKIF--FPRVSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICP-ALEFTRKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGL-----PLERRVNYTRAEEILSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSTEQKYLTLNTE 506          

Query:   16 LILVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTT---GQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHG-IVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVL-KCLQSVEADAIQKKLTMFSENDFLFLP-NPFVPSLD-PMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEG---IALMGQFLAHPG------MYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNG--YGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFA 537
            LI ++ L+  L  +G+    DP +I+  +GK+RG++    NG  Y+ +  +PYA PP GELRF+ P+P    W N  DAT+PP +C Q N    GT    G EDCL V+VY+P   +  +   V+  +H G  AFM G P  +G +  M  G +++V++ YRLG LGF+S  +    GN GL+DQ LAL WIKQ I++FGG+P+ I ++G  AGG+S  L ML        L    IS SG+ ++   ++  +  R  A E+   +GC +      L KCL+S  A  I   +  F    F ++P  PF P+++ P   +  + Q P  I++SG + +VP  +   + +G    AL+ +  A  G      +   + +  P L+  R S  T +   D    +++ YL  ++    +     ++FTD  F   +  +  L +      PV+ +++        G I                     + RN   +G  HGD++FL+F +     P    P  E    +S N ++    FA
Sbjct:    7 LICLIQLWVQLGAAGSVTLLDPLLIEIPNGKLRGRD----NGHYYS-YEAIPYAEPPTGELRFEVPKPYKQQWTNTFDATQPPVLCMQWNQFINGTNKLLGVEDCLTVSVYRPKNSSR-NNFPVVANLHGG--AFMFGGPSQYGHENIMREGSVILVTIGYRLGPLGFVSTGDADLSGNFGLKDQRLALLWIKQNIASFGGEPENILVVGHSAGGASVHLQMLRED--FSKLAKAAISFSGNALDPWVIQ--QGLRGRAFELGRIVGCGQASDSGTLKKCLKSKPAIEIVSAVRSFLV--FSYVPFTPFGPAIESPDAPEAFITQHPIDIIKSGKFSQVPWAVTYTTEDGGYNAALLLEKQASSGRELIVDLNDRWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDVQRMFTDLLFKNSVTVSVDLHRKYGKS-PVYAFVYDNPSEVGVGQI--------------------LSGRNDVYFGTVHGDDVFLIFNVS--FVPANRRPDEE---IISRNFIKMLEYFA 506          

Query:   18 LVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTT---GQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHG-IVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVL-KCLQSVEADAIQKKLTMFSENDFLFLP-NPFVPSLDPMVS-DPLLPQKPEQILQSGHYEKVPIIMGGNSHEG---IALM----GQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKT 539
            L+++L      S A   +DP ++Q   GK+RG++    NG  Y+ +  +PYA PP+G+LRF+ P+P    W +I +ATK P  C Q +    G     G+EDCL V++Y+P   +  S   V+  IH G  AFM G+    G +  M  G  ++V ++YRLG LGF S  +   PGN GL+DQ LALKWIKQ I++FGG+P+ I LIG  AGG+S  L ML  ++  Q L     S SG+ ++   ++  +  R  A E+  ++GC  ++    L KCL+S  A  +   +  F    F ++P  PF P L+P  + D  L Q P ++++SG + +VP  +   + +G    AL+       +A   +   + E  P  +  R ++   + D D    +K  YL  +K    +     +LFTD  F      +  L +     P    Y + Y      G   V A                      +G  HGD+ FL+F+  N +  + + P  E    +S N +    +FA +
Sbjct:    6 LIIVLSCLWLGSNASDPDDPLLVQLPQGKLRGRD----NGSYYS-YESIPYAEPPIGDLRFEAPEPYKQKWSDIFEATKTPVACLQWDQFTPGANKLVGEEDCLTVSIYKPKN-SKRSSFPVVAHIHGG--AFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFASTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPENILLIGHSAGGASVHLQMLR-EDFGQ-LAKAAFSFSGNALDPWVVQ--KGARGRAFELGRNVGCESSEDSASLKKCLKSKPASELVTAVRKFLI--FSYVPFAPFSPVLEPSDAPDAFLTQDPREVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIAIDDLNDRWLELAPYFLFYRDTKTKKDMD-DYSRKIKEDYLGNQKFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPA---YAYVYDNPAEKGIAQVLAN----------------RTDYDFGTVHGDDYFLIFE--NFVREVEMRPDEE---IISRNFINMLADFASS 502          

Query:   30 GAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQ-----------LNLNHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGS-PKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLE-NEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGS---PIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLD--PMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAP---WKLKF-KLFLHSFGIGYNMRNG-------YGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRV-SGNILRTWTNFAKTGTPSRPSDIFQWTPTQAPAMR 560
            G    E+  II T +GKVRG N    +G + A FLG+PYA+PP+G LRFK+PQ  +  W +I +ATK    C Q             + +  T   EDCL +NV+ P T  P +   VM+WI+ G F     S P   G  L     +++VS+NYR+G LGFL+L  N   PGN+GL DQ LAL+W+++ I+AFGG+P  +TL G  AG  S  LH+LSP+  +Q LF   I QSGS   P     L+ A+++    L +A  +GCSK     ++KCL++ +   I         N+ L +P+  + S++  P+V    L   P+ +LQ G ++K  I++G N  EG A +      PG                        D D +            I R   Q G++++  F  + + GR   L   V          +R +     GD ++  P   +  KF +L  ++F   +  R+         GV HG E+  +F L     P+       R + + S +I+  W NFAK G P+   +      T+ PA R
Sbjct:   24 GKSHTEEDIIITTKNGKVRGMNLPVLDGTVTA-FLGIPYAQPPLGRLRFKKPQ-FLTKWSDIWNATKHANSCYQNADQSFPGFPGSEMWNPNTDLSEDCLYLNVWSP-TPKPKN-ATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEIPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAGSVSLHLLSPR--SQPLFTRAILQSGSSNAPWAVMSLDEAKNR---TLTLAKFIGCSKENDTEIIKCLRNKDPQEILL-------NELLVVPSDTLLSVNFGPVVDGDFLTDMPDTLLQLGQFKKTQILVGVNKDEGTAFL--VYGAPGF---------------------SKDNDSI------------ITRKEFQEGLKIY--FPGVSEFGREAILFYYVDLLDDQRAEKYREALDDVLGDYNIICPALEFTTKFSELGNNAFFYYFEHRSSQLPWPEWMGVMHGYEIEFVFGL-----PLERRVNYTRAEEILSRSIMNYWANFAKYGNPNGTQN----NSTRWPAFR 522          

Query:   14 MQLILVLILFNFLPIS---GAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHT------------GTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTF-GPQLWMDHGIVMVSLNYRLGVLGFLSLE-NEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGS---PIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIG-----YNMRNG-------YGVCHGDELFLMFKLGNLLAPMGLGPTSERDKR------VSGNILRTWTNFAKTGTPSRP-SDIFQWTPTQAPAMRFATIGSD--MIMSDVPA----YWERVEFFHRITSQVG 591
            + +I +  LF FL +    G    ED  II T +GKVRG N     G + A FLG+PYA+PP+G LRFK+PQ S+  W +I +ATK    C Q N++ +             T   EDCL +NV+ PA         V++WI+ G F     S   + G  L     +++VS+NYR+G LGFL+L  N  APGN+GL DQ LAL+W+++ I+AFGG+P  +TL G  AG +S  LH+LSP   + SLF   I QSGS   P     L  AR++    L +A   GCS+     ++KCL++ +   I     + +E   +    P   +  P V    L   P+ +L+ G ++K  I++G N  EG A +      PG   +                                 +   I R   Q G+++F  F  + + G+ + L              +R +     GD +   P  L+F      +G       +  R+         GV HG E+  +F L          P   RD        +S +I++ W NFAK G P+   ++   W   ++   ++ T+ ++   IM+ + A    +W    FF ++    G
Sbjct:    5 VTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTA-FLGIPYAQPPLGRLRFKKPQ-SLTKWSDIWNATKYANSCCQ-NIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPA--PKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPG--SHSLFTRAILQSGSFNAPWAVTSLYEARNR---TLNLAKLTGCSRENETEIIKCLRNKDPQEI-----LLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFL--VYGAPGFSKD---------------------------------NNSIITRKEFQEGLKIF--FPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICP-ALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGL----------PLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFW--TSFFPKVLEMTG 562          

Query:   18 LVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTT---GQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHG-IVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVL-KCLQSVEADAIQKKLTMFSENDFLFLP-NPFVPSLDPMVS-DPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAH-------PGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKT 539
            L+++L      S A   +DP ++Q   GK+RG++    NG  Y+ +  +PYA PP G+LRF+ P+P    W +I DATK P  C Q +    G     G+EDCL V++Y+P   +  S   V+  IH G  AFM G+    G +  M  G  ++V ++YRLG LGF S  +   PGN GL+DQ LALKWIKQ I++FGG+P  + LIG  AGG+S  L ML  ++  Q L     S SG+ ++   ++  +  R  A E+  ++GC   +    L KCL+S  A  +   +  F    F ++P  PF P L+P  + D +L Q P ++++SG + +VP  +   + +G       L           +   + E  P  +  R ++   + D D    +K  YL  +K    +     +LFTD  F      +  L +     P    Y + Y      G   V A                      +G  HGD+ FL+F+  N +  + + P  E    +S N +    +FA +
Sbjct:    6 LIIVLSCLWLGSNASDPDDPLLVQLPQGKLRGRD----NGSYYS-YESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVGEEDCLTVSIYKPKN-SKRSTFPVVAHIHGG--AFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFASTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLIGHSAGGASVHLQMLR-EDFGQ-LAKAAFSFSGNALDPWVVQ--KGARGRAFELGRNVGCESAEDSASLKKCLKSKSASELVTAVRKFLI--FSYVPFAPFSPVLEPSDAPDAILTQDPREVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNDRWLELAPYFLFYRDTKTKKDMD-DYSRKIKEDYLGNQKFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPA---YAYVYDNPAEKGIAQVLAN----------------RTDYDFGTVHGDDYFLIFE--NFVREVEMRPDEE---IISRNFINMLADFASS 502          

Query:   16 LILVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTTGQEDCLVVNVYQPATCAPLSP-CAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHS----FGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPS 543
            + ++L+   ++P    K  ED PI+    G +RG +  ++ G+    FL +PYA PP+GELRF+ P+P   SW   RDAT+  P+C  L  + +G  GQEDCL +NV+ P      SP   VMVWIH G F    G+ K F P   +DH +V+V+LNYRLG+LGFLS  +E  PGN G++DQ  AL W+ + I  FGG+P+ +TL G+ AGG++   H+LSP  +++ LFH  I+QSG+ +    +   R+     +++A  LGC       ++ CL++  A  +   ++ F   + +F    F P ++   S+  LP  P  IL++     VP + G N+ +G  +    +  P       +     +L+       E DT + E ++R Y   K I   ++     ++TD  FL  +  +   L++      V+ Y F Y G  S    +GD                         + YG CHGDE+  +F    +L  +     +E+D R+   +   WTNFAKTG P+
Sbjct:   20 MFIILVTVTYIPDGSCKSCEDAPIVMIRQGTLRGFHSATRKGRKIISFLSIPYAAPPIGELRFEAPRPP-NSWDGTRDATEIAPMC--LQPSSSGVLGQEDCLFLNVHTPKLLDEFSPPLPVMVWIHGGGFLVGTGNSKYFPPTYLLDHNVVLVTLNYRLGILGFLSAVDEVLPGNYGMKDQVAALVWVHENIKKFGGNPNCVTLFGSSAGGTNVHFHVLSP--ISKGLFHRAITQSGTALAPFAVSTERALNQ-TMKLASLLGCPAVPTTKLVTCLRTKNASDVAATVSAFQMWEGIFT-TAFAPVVEHSGSNRFLPDTPLNILKANKSAPVPRLTGVNAQDGCIISESIIGDPTKVIQMDKQFKDFVLDTLYFRRQENDTSVAETIRRFYFGNKHIDDESVSEVTNMYTDSYFLYPMNWSAT-LEAAAGNRKVYVYYFTYVGAASNSILYGD-----------------------KEHNYGSCHGDEILYLFPSKAILPNVT---QNEQDHRMIDILTTLWTNFAKTGQPT 518          

Query:   39 IIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLN-LNHTGTTGQEDCLVVNVYQPA--TCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVE----ADAIQKKLTMFSENDFLFLPNPFVPSLDPMVS--DPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNR-ASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIF---QWTPTQAPAMRFATIGSDMIMSDVPAYWERVEFFHRITSQV 590
            ++ T  GK+RGK  M+ NG  Y  F G+PYA+PP+G LRFK PQ     W  +RDA      C Q++ +      G EDCL +NVY P   + A  +  AVMVWIH G F         FGPQ  ++  +V+V++NYRLG LGFLS  +   PGN GL+DQ +AL+W++Q I+ FGGDPD +TL G  AGG+   LH+LSP  +++ LFH  I+QSGS +      F R  R  A     +LG      + +   L++V      +A+ +      E D       F P+ +P  S  D  LP +PE ++ +  + KVP+I G   +EGI  + + +  P + + F     LL+     S++  +   + V  +K+ Y   + I R N++  I +  D   L  + +  + + S  +  PV+ YIF + G               K  L   + G G   R   G CHGDEL  +F +  L     + P S  + R    I+R WTNFAKTG P+   D     +W P          IG  + +   P   +R+EF+  +  +V
Sbjct:    6 VVTTRQGKLRGKRVMTANGVAYYSFKGIPYAKPPIGALRFKAPQEP-EPWLGVRDALADGAPCPQIDEVFKEDYKGDEDCLFLNVYSPQIPSWAKCTLRAVMVWIHGGAFCSGSVCTSVFGPQFLIEKDVVLVTMNYRLGALGFLSTGDSVIPGNNGLKDQVMALRWVQQNIAQFGGDPDNVTLFGESAGGTCVHLHLLSP--MSKGLFHRAIAQSGSSL--NPWSFDRKPRLRAFSFGEALGFKTDDSQKLADFLRTVHPKLLIEAVPQARKFEPERDLGI--TFFKPTSEPRTSTEDVFLPDRPEVLMAARKFHKVPLITGAVENEGIFAVKEVIEKPSLISRFNGRFELLVPKELNSKKNPDKYQEDVGRIKKFYFGDEAISRQNLERYIAMNGDIMILNGVYKQAK-IHSALSSAPVYFYIFTFDG---------------KRGLMKRAVG-GSRFR---GPCHGDELPYIFHVDMLRK---MDPKSP-EMRTVERIVRLWTNFAKTGNPTPDGDSLLQIKWRPVTTSVFPCMNIGPALRIDHFPEMKKRMEFWDDLDEEV 539          

Query:   36 DPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTTGQEDCLVVNVYQPATCAPLSP-CAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHS----FGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPS 543
            D PI+    G +RG +  ++ G+    FL +PYA PP+GELRF+ P+P   SW   RDAT+  P+C  L  + +G  GQEDCL +NV+ P      SP   VMVWIH G F    G+ K F P   +DH +V+V+LNYRLG+LGFLS  +E  PGN G++DQ  AL W+ + I  FGG+P+ +TL G+ AGG++   H+LSP  +++ LFH  I+QSG+ +    +   R+     +++A  LGC       ++ CL++  A  +   ++ F   + +F    F P ++   S+  LP  P  IL++     VP + G N+ +G  +    +  P       +     +L+       E DT + E ++R Y   K I   ++     ++TD  FL  +  +   L++      V+ Y F Y G  S    +GD                         + YG CHGDE+  +F    +L  +     +E+D R+   +   WTNFAKTG P+
Sbjct:    1 DAPIVMIRQGTLRGFHSATRKGRKIISFLSIPYAAPPIGELRFEAPRPP-NSWDGTRDATEIAPMC--LQPSSSGVLGQEDCLFLNVHTPKLLDEFSPPLPVMVWIHGGGFLVGTGNSKYFPPTYLLDHNVVLVTLNYRLGILGFLSAVDEVLPGNYGMKDQVAALVWVHENIKKFGGNPNCVTLFGSSAGGTNVHFHVLSP--ISKGLFHRAITQSGTALAPFAVSTERALNQ-TMKLASLLGCPAVPTTKLVTCLRTKNASDVAATVSAFQMWEGIFT-TAFAPVVEHSGSNRFLPDTPLNILKANKSAPVPRLTGVNAQDGCIISESIIGDPTKVIQMDKQFKDFVLDTLYFRRQENDTSVAETIRRFYFGNKHIDDESVSEVTNMYTDSYFLYPMNWSAT-LEAAAGNRKVYVYYFTYVGAASNSILYGD-----------------------KEHNYGSCHGDEILYLFPSKAILPNV---TQNEQDHRMIDILTTLWTNFAKTGQPT 479          

Query:   21 ILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLN--LNHTGTTGQEDCLVVNVYQPATCAPLSP---CAVMVWIHPGEFAFMDGSPKT--FGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQ--KKLTMFSENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLN-RASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIFQWTPTQAPAMRFATIGSD-MIMSDVPAYWERVEFFHRITSQVGLKP 594
            IL NF   S  +Q + P +   + G++ G    S +G+ +  F  +PYA PPVG+LRFK P P+  +W  + DA++  PIC+Q N  +      GQEDCL +NVY P      S      VMVWIH G F    G+ +   FGP   +D  +V+V+ NYRLG LGFLS E+  APGN GL DQ+LAL+W+   +  FGGDP+ IT+ G  AGG+S   H+LSP   ++  FH  I QSG+      L+    +  Y   +A  L C       +L+CL++  A+ I   ++     E  F   P  FVP +D     P +P +PE+++    + +VP+I+G   +EG  +   F           +  P+  L+   + E      ++ ++V   YLD ++ +   M+   Q+ +D+        +  L     N  P F Y + + G  SF  +                  +G      +GVCH DELFLMF  G L  P+   P    D +VS  +L  WT+FAK G P       QW P +   MR+  I S    ++D   +  R+ F+ R+  Q  L P
Sbjct:    3 ILSNF--SSAGEQQQQPVVDIPTLGRLVGSQLSSASGRKFHAFRAIPYALPPVGDLRFKDPIPA-KTWDEVLDASREGPICTQFNSIMADVFVHGQEDCLYLNVYTPQLKTAGSDRHLLPVMVWIHGGAFYMGSGNGENDRFGPGYILDRDVVLVTFNYRLGPLGFLSTEDVDAPGNYGLLDQSLALRWVSDHVGHFGGDPNSITIFGESAGGASVDFHVLSP--YSKGFFHRAIIQSGTAKCPWVLDTPVGE--YTKILAEHLDCPTATSGELLQCLRTRSAEDIVGIRRNIALPELGFGMFPMAFVPRIDRERKLPFVPARPEKLIMEKKFNQVPLILGVVRNEGALVSSSFFLSGNRVMQAFKDDPIRTLSFLINMEKRPDGLEMAQLVHDRYLDKQQNYEDQMEQIEQIISDYGLFKCTDDSVNLFSQF-NDYPTFYYFYTHRGQFSFPQL------------------VGIKPEMDFGVCHADELFLMFTAGYL--PLISTPD---DVKVSETLLDLWTSFAKDGAPRSQHVDDQWLPVEQGKMRYLNINSQPTFVNDKMPFERRLAFWDRMKVQNRLLP 556          

Query:   38 PIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTT-GQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQK--KLTMFSENDFLFLPNPFVPSLDPMVS--DPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTES----LPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIFQWTPTQAPAMRFATIGSDMIMSDVPAYWERVEFFHRITSQVGL 592
            PI+    GK++G  +   +G  Y  F G+ Y +PP+GELRFK P P +  W  IRDA +  P+C Q +++      G EDCL +NVY   +  P S   VMV+IH G F    G+ +T+GP+ +  H +++V++NYRL VLGFLSL+    PGN G++DQ LAL+W+K+ IS FGGDPD ITL G  AG + AILHMLSP  ++Q LF  VI+QSG+ +    +      RA+    A +LG        +L  L+   A  + +    T  ++  +  LP  F P+++      +  L + P  +L +G   KVP+I+G NS EG+ ++     H        E     +P  +  + S+ET +   +L + +K+ Y   + +   + Q  + L TD +F  Q  R     Q      PV+ Y F Y                      L+     + + +  G CH D+LF  F   +      +   +E+ ++V   + + WT+FAKTG P+   ++ +W P       +  +  ++ +S+     ERV+F+++I + VGL
Sbjct:    4 PIVTVKQGKLKGAVNKCLDGSPYYSFKGIRYGQPPIGELRFKAPLP-VKPWTGIRDAIEHGPVCPQFDMSIVDIVEGNEDCLSLNVYT-KSLQPSSKLPVMVYIHGGAFLSGSGNSETYGPEFFFQHDVILVTINYRLEVLGFLSLDTPEVPGNAGMKDQVLALRWVKENISTFGGDPDNITLFGESAGAACAILHMLSP--MSQGLFDRVITQSGNCLSYWSIFHEPVARAF--RAAKALGKEAKDTNELLSYLREFPAVELARLSIQTRTTDEKYRGLPIYFTPTIEKKFEGQEQFLTEDPLDLLMAGKISKVPMIIGYNSAEGLLMVND---HVKKIKTLNEQPSYFVPRDIATKVSKETLD---ELGQRIKKFYFGNRDMTPEDRQAIVDLQTDINFTYQTHRFIHFFQKF---APVYLYKFEYCTE-------------------LNVVKSVFGLDSVKGSCHADDLFYFF---HSEVSRSIYDENEKLRKVIYQLTKFWTDFAKTGNPTPTKEVVEWLPCSPANKEYLILDEELKLSN-NLDKERVDFWNKIYADVGL 529          

Query:   38 PIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQP--SIASWKNIRDATKPPPICSQLNLNHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSE-----NDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESL-PLLMLNRASQETTEGDTDLVE-VVKRAYLDTKKIFRLNMQHGI-QLFTDF----SFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPS 543
            PI++T  G  RG+  +S+ G+ +  F G+PYA+PPVG  RFK P+P      W  + D    PP C QL++   G TG EDCL +NVY P T +  +   V+V++H G FA  +      GP  +MD  +V+V+L+YRLG LGFLSLE++   GN GL DQ  AL W+K+ I  FGG+P ++TL+G  AG  S   H+ SP   +Q LFH  I QSGS +    L+ +R    YAL++  S+GC  T    ++ CLQ      I ++  +F E     + F+  P P++P  DP      +PQ P  +++ G   K+P+++G N  EG+    +F+     Y  F ++L   L+LN  S     G+  L E VV RA+   K+   +     I Q FTD      F+    + T+LL++  N   V++YIF Y G+ S+ DI   +  ++ F       G+  ++R   G  H DEL  +F    LL  +   PT E D+ VS N+++ WT+FAK+G P+
Sbjct:   41 PIVETKQGPARGEQWVSRGGQSFHSFRGIPYAKPPVGRRRFKLPEPFQENDRWSKVLDFASNPPSCPQLSVLGIGVTGNEDCLYLNVYTP-TLSQSALLPVLVYVHGGGFAVGECGSSVCGPHNFMDKQVVLVTLHYRLGPLGFLSLESDNMQGNQGLWDQREALLWVKKNIKEFGGNPKQVTLLGESAGAMSVGFHLTSPS--SQGLFHRAILQSGSSLTSA-LKPSRRPSYYALKLGESVGC--TDESTLIPCLQDTPVKQIIEQTLLFDECGMRSDYFMSNPGPWIPVSDPYADKSFIPQDPGSLVEQGLSSKIPVLIGFNEAEGLLYSTRFIKDTEFYQYFKKNLDKCLVLNTLSM----GEDGLEEKVVSRAHHLVKEYNGIQDGEMINQGFTDMVGDARFILSAHQHTELLRNQNN--TVYRYIFSYVGSSSYADIFSSSLPEIIFNTIKRYLGLSDSLR--LGASHVDELIYLFS-NPLLHHL---PTQE-DQLVSENMIKWWTSFAKSGNPN 541          

Query:   35 EDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTT-GQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQK--KLTMFSENDFLFLPNPFVPSLDPMVS--DPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTES----LPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIFQWTPTQAPAMRFATIGSDMIMSDVPAYWERVEFFHRITSQVGL 592
            ++ PI+    GK++G  +   +G  Y  F G+ Y +PP+GELRFK P P +  W  IRDA +  P+C Q +++      G EDCL +NVY   +  P S   VMV+IH G F    G+ +T+GP+ +  H +++V++NYRL VLGFLSL+    PGN G++DQ LAL+W+K+ IS FGGDPD ITL G  AG + AILHMLSP  ++Q LF  VI+QSG+ +    +      RA+    A +LG        +L  L+   A  + +    T  ++  +  LP  F P+++      +  L + P  +L +G   KVP+I+G NS EG+ ++     H        E     +P  +  + S+ET +   +L + +K+ Y   + +   + Q  + L TD +F  Q  R     Q      PV+ Y F Y                      L+     + + +  G CH D+LF  F   +      +   +E+ ++V   + + WT+FAKTG P+   ++ +W P       +  +  ++ +S+     ERV+F+++I + VGL
Sbjct:   28 KENPIVTVKQGKLKGAVNKCLDGSPYYSFKGIRYGQPPIGELRFKAPLP-VKPWTGIRDAIEHGPVCPQFDMSIVDIVEGNEDCLSLNVYT-KSLQPSSKLPVMVYIHGGAFLSGSGNSETYGPEFFFQHDVILVTINYRLEVLGFLSLDTPEVPGNAGMKDQVLALRWVKENISTFGGDPDNITLFGESAGAACAILHMLSP--MSQGLFDRVITQSGNCLSYWSIFHEPVARAF--RAAKALGKEAKDTNELLSYLREFPAVELARLSIQTRTTDEKYRGLPIYFTPTIEKKFEGQEQFLTEDPLDLLMAGKISKVPMIIGYNSAEGLLMVND---HVKKIKTLNEQPSYFVPRDIATKVSKETLD---ELGQRIKKFYFGNRDMTPEDRQAIVDLQTDINFTYQTHRFIHFFQKF---APVYLYKFEYCTE-------------------LNVVKSVFGLDSVKGSCHADDLFYFF---HSEVSRSIYDENEKLRKVIYQLTKFWTDFAKTGNPTPTKEVVEWLPCSPANKEYLILDEELKLSN-NLDKERVDFWNKIYADVGL 556          

Query:   36 DPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNLNHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFS--ENDFLFLPNPFVPSLDPMVSDPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLG-PTSE-RDKRVSGNILRTWTNFAKTGTP-SRPSDIF--QWTPTQ 555
            + PI+Q   GK+RG    + NGK +  F G+PYA+ PVG LRFK P+P    W  +R+ATK   IC+Q +      +G +DCL +NVY      P +P A +VWIH G F F  G    FGP L ++  IV+V++NYRLGVLGFL+LE+EA PGN GL+DQ +ALKW++Q I+ FGGDP+ +T+ G  AG SS  +H L+   + Q LFH  I QSG          A S +  A+ ++  LG   T  + +++ LQS +A  + K    F+  +N FL   NPF+PS+D    +P L     + ++SG   KVP I+G  SHEGI  + +       Y+     L  L+L+ +++   +     V  +K+ ++D KKI   N Q    L +   FL  I    ++   +P G P + Y F +    +    ++++                    +  G  H ++L  +F    LLA +G+  P+S   +  +    +  WTNFA+TG P +  SD+   +W P  
Sbjct:    3 ESPIVQIHQGKLRGAIEKNMNGKDFYAFRGIPYAKSPVGALRFKDPEPQ-EPWSGVREATKFGNICAQFDWITKKISGSDDCLFLNVYS-TNLTPDTPRATLVWIHGGGFVFGSGDDDLFGPDLLIEKDIVLVTINYRLGVLGFLNLEDEACPGNQGLKDQVMALKWVQQNIAKFGGDPNNVTIFGESAGASS--VHFLTISPLAQGLFHKAILQSGVATCPWASSSANSMKEKAIVLSSVLGNEITDTKKLIEYLQSFDALELVKAERSFASWKNRFLIW-NPFLPSIDSKSKNPFLDIPLAEAVKSGI--KVPHIIGYTSHEGIIDLVEL--EKDKYSEIDADLENLLLHPSAKNFLKEFNISVRDLKKIFMDDKKISAENGQSLANLRSASDFLAPIHHVLEIQPRIP-GIPTYLYKFDHYSKETAVVQNLFS-------------------SDLEGTSHAEDLMYLFN-AKLLAALGIKLPSSYPTESLIQKRFIDLWTNFAETGNPVTETSDLISVKWQPVD 499          

Query:   17 ILVLILFNFLPISGAKQFEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATKPPPICSQLNL---NHTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIEDKQLEFARSKRAYALEVAGSLGCSKT--KMEHVLKCLQSVEADAIQKKLTMFSENDFLFLPNPFVPSLDPMVS-------DPLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHP----GMYANFTESLPLLMLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLN----MQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIFQWTPTQAPAMR 560
            +  L++  ++     K+  D P++ TS+G+VRG  + S++G+ +  F G+PYA+ PVG+LRFK PQP I +W    DATK  P+C Q N     +    G EDCL +NVY P T   L    VMV+IH G F    G+    GP+ +MD  +V+V+ NYRLG  GFLS  ++ APGN  L+DQ  ALKW++  I+ FGG+ D++T+ G  AG  S   H+LSP  +++ LFH  IS+SGS +          +       A  +GC  +      +++CL++V A+ + K    F      FL    V     +         +P   ++P + + +G ++ VP I+G    EGI  +   +  P       ANFT  LP +++   S    EG+   ++ +   YL+ +    +N    +Q  I L+T  SF       + +L S     PV+ Y FRY G +S+GD+                 G   N+   +GV H DEL  +FK  + L P  + PTS     V   +++ WTNFAKTG P   S +  W P    ++ 
Sbjct:    9 VFALVVLGYVE---CKRCSDNPVVCTSYGEVRGSYNASRHGRRFMSFRGIPYAQAPVGQLRFKEPQP-IEAWTGQWDATKEGPVCIQTNYLFYQNPPVEGVEDCLYLNVYTPRTDGEL---PVMVFIHWGAFTAGRGTSDYIGPEYFMDQDVVLVTFNYRLGAFGFLSTLDDEAPGNYALKDQVAALKWVQANIANFGGNKDKVTIFGQSAGAGSVHYHLLSP--LSKGLFHHAISESGSALSLWAKPLNALQPTVVQATAALVGCQSSIGNSTQLVECLRNVPAETLAKSFGAFK-----FLGMDSVSVFSSVTEKQTERNPNPFFTKEPLEYILAGEFQNVPWILGTVEDEGIIRVASLVRQPKQLEAFNANFTSLLPQMLVLSVSTTDVEGE---LKNITDHYLNGQPFLDVNDPNSIQGMIDLYTGRSF-SYGSYQSAMLHSAMGHNPVWFYNFRYRGEYSYGDLFA---------------GTDNNVDFHWGVSHCDELLYLFK--SSLFPDLIDPTSNAMVDV---MIQLWTNFAKTGKPVD-STVLDWQPLNVKSLE 533          

Query:   34 FEDPPIIQTSHGKVRGKNHMSQNGKLYAQFLGLPYARPPVGELRFKRPQPSIASWKNIRDATK---PPPICSQLNLN-HTGTTGQEDCLVVNVYQPATCAPLSPCAVMVWIHPGEFAFMDGSPKTFGPQLWMDHGIVMVSLNYRLGVLGFLSLENEAAPGNLGLRDQALALKWIKQEISAFGGDPDRITLIGAGAGGSSAILHMLSPQNVNQSLFHGVISQSGSPIED-KQLEFARSKRAYALEVAGSLGCSKTKMEHVLKCLQSVEADAIQKKLTMFSENDFLFLP-NPFVPSLDPMVSD----PLLPQKPEQILQSGHYEKVPIIMGGNSHEGIALMGQFLAHPGMYANFTESLPLL---MLNRASQETTEGDTDLVEVVKRAYLDTKKIFRLNMQHGIQLFTDFSFLGQIGRTTQLLQSVPNGPPVFQYIFRYSGTHSFGDISVYAPWKLKFKLFLHSFGIGYNMRNGYGVCHGDELFLMFKLGNLLAPMGLGPTSERDKRVSGNILRTWTNFAKTGTPSRPSDIFQW---TPTQAPAMRFATIGSDMIMSDVPAYWERVEFFHRI 586
             ED P ++T  G ++G   +S NGK Y  + G+PYA PPVG+ RFK PQ  I +W     ATK   P    +QL +N      G EDCL +NVY PA   P     V+ WIH G F F  G P   G +  MD  ++ V++NYRLG+LGFLS E+E  PGN+GL+DQ++AL+W+ + I  FGG+P RITLIG  AGG+S   H LSP  ++  LF G IS SG+ +    Q E +  K   A +V   +GC    ++ +++CL+   A AI + L  F    F + P  PF P  + + +D    P + + P +I+ SG  + VP + G  S EG+  + +F+A P       E+  L+    L+       E   ++  +++  Y ++ KI    ++H I + +D  F+   G     +Q+  N  PV+ Y + Y G HS  +I                        N YGVCH D+ +++        P     T+  D ++   ++  W +F   G P+  S   QW    P +         G   I  D    + R +F++ I
Sbjct:   19 LEDAPRVKTPLGAIKGYYKISGNGKQYEAYEGIPYALPPVGKFRFKAPQ-KIPAWIGELSATKFGFPCLQYTQLPVNPRDKIEGAEDCLYLNVYVPADRTPSQSLPVIFWIHGGAFQFGSGIP--MGAKYLMDSDVIFVTINYRLGILGFLSTEDEVVPGNMGLKDQSMALRWVSENIEWFGGNPKRITLIGLSAGGASVHYHYLSP--LSAGLFQGGISISGTALNCWTQTENSLEK---AKQVGAFMGCPTRNVKEMIRCLRYRPARAIVETLANFMR--FYYNPFTPFGPVTEKVNNDSNSLPFIDRTPIEIINSGDVQDVPWVTGVTSEEGLYPVAEFIAKPEALKLLDENWDLIAPYFLDYNYTIPKEKHVEVARLIRNYYFESNKIDETTLKHLIDVASDRFFITD-GEKAARMQAKVNRQPVWFYYYTYKGAHSISEIMS-------------------GTSNKYGVCHADDAYMVVD-----TPFLASTTTTNDIKMQKVLIDFWVSFVNNGVPNVNS--VQWPRLNPNEKSLHYLHIAGPGKIQMDSSTNFGREDFWNSI 550