BLAST of dihydropyrimidine dehydrogenase vs. L. salmonis genes
Match: EMLSAG00000001514 (supercontig:LSalAtl2s:LSalAtl2s125:349817:362791:1 gene:EMLSAG00000001514 transcript:EMLSAT00000001514 description:"maker-LSalAtl2s125-augustus-gene-3.14")

HSP 1 Score: 1152.12 bits (2979), Expect = 0.000e+0
Identity = 552/776 (71.13%), Postives = 637/776 (82.09%), Query Frame = 0

Query:   10 GCVSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCN----CKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHH--INIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVI---KVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYG 776
             C++ DTPDIENL+ LNPK KPY N VPS+VTK NKKHWKRN D +E +  CG+C  TLFK+F+DIKHT+LSERAAL ES+RCLKC DAPCQKSCPTQLDVKSFIGSISTKNYYG+AK+ILSDNPLGLTCGMVCPTSDLCVGGCNL ASEEG INIGGLQ FAVEMF+K +IPQVLPP + K  P+SY +KI L+GCGPASISC TFL R+GY D+T++EK+E+VGGLN+SELP++RLPYD+ N+E                                  A+F+GIGNPEPKKIPIFE L+E+ GFFT KDFLPKVAKASK GM +    C   LPEL+G+VIVLGAGDTAFDCATSA+RCGAKRVFVVFRKGF+NIRAVPEEME+AREEKCEFLPFM+P +VV  + GR++HLVLAR E  D+G W+ D++Q++KKKC+F+ISAFGSGLY+ D+K +L P+K NRWG  EVD++   TSE W F GGD+AG AETAVEA NDGK+A+WS+HRYLQR       I  EP LPKFYTPIDDVD+SVE+CG+KF+NPFGLASAPPATTWPMIRRGFEAGW FVVTKTF LDKDIVTNV+PRIVRGTTSGH+YGPGQ SFLNIELI+EKTA YWC+G+ EIK DFP  +IIAS+M S+DK DWQE+   A  +GADALELNLSCPHGMGERGMGLACGQ+  +V++ICQWV  V+   K+PFFAKLTPNVTNIV IA AAK+GGADG TAINTVSGLMG NSKG AWP+  V KKTTYG
Sbjct:    4 ACITRDTPDIENLLQLNPKKKPYTNLVPSIVTKTNKKHWKRNEDNSEKLKGCGTCETTLFKDFNDIKHTSLSERAALLESSRCLKCADAPCQKSCPTQLDVKSFIGSISTKNYYGAAKAILSDNPLGLTCGMVCPTSDLCVGGCNLAASEEGAINIGGLQQFAVEMFKKAKIPQVLPPYISKNRPDSYNSKIALIGCGPASISCATFLGRLGYRDITIFEKDEFVGGLNSSELPAFRLPYDM-NYE----------------------------------AIFVGIGNPEPKKIPIFEKLTESNGFFTXKDFLPKVAKASKNGMVSKCSGCVPQLPELFGDVIVLGAGDTAFDCATSAIRCGAKRVFVVFRKGFSNIRAVPEEMEVAREEKCEFLPFMSPEDVVLDSKGRITHLVLARNELDDEGNWYVDKDQSLKKKCNFVISAFGSGLYNSDIKAALEPLKFNRWGGLEVDNLTGKTSEEWVFSGGDIAGVAETAVEAXNDGKVASWSIHRYLQRNAEGFEKISTEPQLPKFYTPIDDVDISVEVCGMKFVNPFGLASAPPATTWPMIRRGFEAGWAFVVTKTFGLDKDIVTNVSPRIVRGTTSGHNYGPGQSSFLNIELISEKTANYWCQGVAEIKKDFPDRIIIASVMASFDKSDWQEICIKAAQSGADALELNLSCPHGMGERGMGLACGQNVDMVRSICQWVSEVVKNYKIPFFAKLTPNVTNIVDIAKAAKQGGADGVTAINTVSGLMGLNSKGVAWPN--VMKKTTYG 742          

HSP 2 Score: 246.514 bits (628), Expect = 3.150e-68
Identity = 110/194 (56.70%), Postives = 142/194 (73.20%), Query Frame = 0

Query:  857 DELDEWDGQSPPTARTYKGKPV-VNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDLDQSWKPRLPDLQLR 1049
            +ELD+WDG +PPT RTYKGK V V L + +  N  +PNFGPY K+K+  + +  K  D + + ++    P   P+  +P V+EVIG+ALD IG Y DL  ++HV+A+IDPEMCINCGKCYM CNDTGY AIEFD ETH+P V  D CTGCTLCYSVCP+I+CI+M+ R+D Y P RG+ L   WKPRLP+LQ++
Sbjct:  743 EELDDWDGLAPPTERTYKGKSVDVKLSETLKKN--IPNFGPYIKEKKKIMYENNKNSDPISNQKLPXNXPANVPTRNLPQVKEVIGKALDYIGAYKDLSQREHVIAMIDPEMCINCGKCYMXCNDTGYXAIEFDPETHIPRVLEDKCTGCTLCYSVCPVIDCIQMIQRKDDYIPNRGVSLSADWKPRLPELQVK 934          

BLAST of dihydropyrimidine dehydrogenase vs. L. salmonis genes
Match: EMLSAG00000004194 (supercontig:LSalAtl2s:LSalAtl2s221:469662:476711:-1 gene:EMLSAG00000004194 transcript:EMLSAT00000004194 description:"augustus_masked-LSalAtl2s221-processed-gene-4.2")

HSP 1 Score: 93.9745 bits (232), Expect = 1.620e-19
Identity = 114/486 (23.46%), Postives = 197/486 (40.53%), Query Frame = 0

Query:   70 KNFDDIKHTTLSERAALRESNRCLKCVDAPCQKS---CPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVE-MFQKMRIPQVLPPDVPKPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEK------CEFLPFMAPMEVVTR------------------ADGRVSHL--VLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWA-----FCGGDLAGTAETAVEAVNDGKIAAWSMHRYL 520
            K++D+I       ++   ++ RC+ C    C  +   CP    +  F   +    +  + K++L  N      G VCP    C G C L  +   P+ I  ++   ++  F+   I         K  P      I ++G GP+ ++    L + G+N VTVYE+   +GGL    +PS +L  ++V   VD+M + G+  +    + +S++    L ++    A+    G+  P+ IPI  P  ++ G   + +FL K+ + +   + +    +     +VIV+G GDT  DC  S+LR GAK +        T    +P+  EL  E+         F       EV+ +                   +GR+S +  V    E+ D G W   E    +K     +     G    D KK L  + +      E+D      ++ +A     F  GD        V A+ +G+ AA  +  YL
Sbjct: 1367 KDWDEIYDFPKVRKSLKVQAARCMDCGVPFCHSNNHGCPLGNVIPRFNDLVFHDQWKEALKTLLQTNNFPEFTGRVCPAP--CEGSCVLGINSP-PVTIKNIECAIIDKAFENGWI---------KAQPPLKXKTIAIIGSGPSGLAAADQLNKAGHN-VTVYERNNRIGGLLQYGIPSMKLSKEIVQRRVDLMTEEGINFKVNSTINESNI----LELKKEYDALLFCTGSTIPRDIPI--PGRKSTGIHFAMEFLQKLQQKN---LGDEVKTIDAKDLDVIVIGGGDTGNDCIASSLRQGAKSI--------TTFEILPQPTELRGEDNPWPQFPRIFKVDYGHQEVIVKNGNDPRRYSTMSKEFLSDENGRISGIRTVCVSWEKDDKGRWVMSEVPNSEKLYPAQLVLLCMGFLGPD-KKVLDYLNI------ELDPRGNIQTKDYAVGNGIFAAGDCRRGQSLVVWAITEGRQAARKLDEYL 1815          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|82185925|sp|Q6NYG8.1|DPYD_DANRE (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase)

HSP 1 Score: 1407.89 bits (3643), Expect = 0.000e+0
Identity = 690/1029 (67.06%), Postives = 822/1029 (79.88%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKP--LPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKER--DILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDLD 1036
            +S +  DIE+++ALNP++K +AN   +   K  KKHWKRN ++     SC SC + L  NFDDIKHTTLSER ALRE+ RCLKC DAPCQKSCPT LD+KSFI SIS KNYYG+AK+ILSDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FA E+F KM IPQ+  P++P    +P+S+  +I L+GCGPASISC +FLAR+GY+++T++EK++Y+GGL+TSE+P +RLPY+VV FE+D+MKDLGVKV   + LGQ+ LTL  L  E G + V+IGIG P+  +  IFE L+  QGF+TSKDFLP VAKASK GMCNC+S LP+L+GNVIVLGAGDTAFDCATSALRCGA+RVFVVFRKGFTNIRAVPEEME A+EEKCEFLPF++P EV+ + +GRVS L   RTEQ DDGTW  DEEQ +  K DFIISAFGS L    + K+L P+KLNRWGTPEV+S  M T+E W F GGD+AG A T VE+VNDGK A+W +H+Y+Q LH   I   P LP F+  ID VD+SVEMCG+KF NPFGLASAPP T+  MIRR FE GWGF +TKTF LDKD+VTNV+PRIVRGTTSGH +GPGQGSFLNIELI+EKTAAYWCK + E+K DFPK++IIASIMCSY++ DW ELAKMA+ + ADALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR    +PFFAKLTPNVTNIV IA+AA EGGADG TA NTVSGLM   +    WP +G   +TTYGG+SGNA+RP+ALRAVSAIA+ALPGFPILATGGIDSA+  LQFL AGASV+QV SA+QNQDFTV++DY  GLK LLYL+SI+EL +WDGQSPPT R  KGKPV ++ ++IG  K LP+FGPY + K  ALAK KK+   D++ D          KP   IP+V++VI RAL  IG Y +LDN + V AL+DPEMCINCGKCYMTCND+GYQAI+FD ETH+P +  D+CTGCTLC SVCPII+CIKMV R   Y+PKRG+ ++
Sbjct:    5 LSKELQDIESILALNPRVKSHANVHSTASKKNEKKHWKRNPER-----SCDSCVN-LENNFDDIKHTTLSERGALREALRCLKCADAPCQKSCPTNLDIKSFITSISNKNYYGAAKAILSDNPLGLTCGMVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEVFSKMGIPQIRNPELPTADNMPKSFHTRIALIGCGPASISCASFLARLGYDNITIFEKQKYIGGLSTSEIPQFRLPYEVVQFEIDLMKDLGVKVVLEKGLGQNGLTLTSLKEE-GYQVVYIGIGLPQANRDKIFEGLTTEQGFYTSKDFLPLVAKASKIGMCNCRSQLPKLHGNVIVLGAGDTAFDCATSALRCGARRVFVVFRKGFTNIRAVPEEMEAAKEEKCEFLPFLSPHEVIKK-NGRVSGLRFCRTEQQDDGTWIVDEEQIVHLKADFIISAFGSMLNDPAVTKALDPIKLNRWGTPEVNSETMQTTEPWVFAGGDIAGFANTTVESVNDGKQASWHIHKYIQSLHGNTISATPRLPLFHCSIDTVDISVEMCGIKFPNPFGLASAPPTTSAAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVRGTTSGHIFGPGQGSFLNIELISEKTAAYWCKSVAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRKATSIPFFAKLTPNVTNIVDIATAAYEGGADGVTATNTVSGLMALKADATPWPGIGRGARTTYGGVSGNAIRPIALRAVSAIARALPGFPILATGGIDSAESGLQFLHAGASVLQVCSAVQNQDFTVIEDYCLGLKALLYLKSIEELHDWDGQSPPTIRHQKGKPVPHVSELIG--KSLPSFGPYLQTKTQALAKYKKDASGDVIMDTGAARVNIPKKP---IPNVKDVIARALKHIGAYQELDNTEQVQALVDPEMCINCGKCYMTCNDSGYQAIKFDPETHLPVI-TDSCTGCTLCLSVCPIIDCIKMVSRTTPYEPKRGLPVN 1019          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|81878130|sp|Q8CHR6.1|DPYD_MOUSE (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase)

HSP 1 Score: 1402.11 bits (3628), Expect = 0.000e+0
Identity = 664/1029 (64.53%), Postives = 816/1029 (79.30%), Query Frame = 0

Query:    9 SGCVSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKP--LPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDL 1035
            +G +S D PDIE+++ALNP+++ +A    +   K +KKHWKRN DK     +C +C + L  NFDDIKHTTL ER ALRE+ RCLKC DAPCQKSCPT LD+KSFI SI+ KNYYG+AK I SDNPLGLTCGMVCPTSDLCVGGCNL A+EEGPINIGGLQ FA E+F+ M IPQ+  P +P P  +PE+Y AKI L G GPASISC +FLAR+GY+++T++EK+EYVGGL+TSE+P +RLPYDVVNFE+++MKDLGVK+  G+ L   ++TL  L  E G +A FIGIG PEPKK  IF+ L++ QGF+TSKDFLP VAK+SK GMC C S LP + G VIVLGAGDTAFDCATSALRCGA RVF+VFRKGF NIRAVPEEMELA+EEKCEFLPF++P +V+ + DG++  +   RTEQ + G W  DEEQT++ K D +ISAFGS L    +K++L+P+K NRWG PEV+   M TSE W F GGD+ G A T VE+VNDGK A+W +H+++Q  +  ++P +P +P FYTP+D VD+SVEM GL+F NPFGLASA PAT+ PMIRR FEAGWGF +TKTFSLDKDIVTNV+PRI+RGTTSG  YGPGQ SFLNIELI+EKTAAYWC  + E+K DFP +++IASIMCSY+K DW EL+KMAEA+GADALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR  ++VPFFAKLTPNVT+IV IA AAKEGGADG TA NTVSGLMG  + G  WP+VG+ ++TTYGG+SG A+RP+ALRAV+AIA+ALPGFPILATGGIDSA+  LQFL +GASV+QV SAIQNQDFTV++DY TGLK LLYL+SI+EL +WDGQSPP     KGKPV  + +++G    LP+FGPY +Q++  +A +K  +           R  +     IP++++VIG++L  +GT+ ++   + VVALID EMCINCGKCYMTCND+GYQAI+FD ETH+P V +D CTGCTLC SVCPI++CI+MV R   YQPKRG+ L
Sbjct:    2 AGVLSRDAPDIESILALNPRVQAHATLRSTAAKKLDKKHWKRNTDK-----NCFTC-EKLESNFDDIKHTTLGERGALREAVRCLKCADAPCQKSCPTSLDIKSFITSIANKNYYGAAKLIFSDNPLGLTCGMVCPTSDLCVGGCNLHAAEEGPINIGGLQQFATEVFKAMNIPQIRNPSLPPPEHMPEAYSAKIALFGAGPASISCASFLARLGYSNITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSTDEMTLSSLK-ENGYRAAFIGIGLPEPKKDHIFQGLTQVQGFYTSKDFLPLVAKSSKTGMCACHSPLPSIRGAVIVLGAGDTAFDCATSALRCGALRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVK-DGKIVAMQFVRTEQDETGNWVEDEEQTVRLKADVVISAFGSVLEDPKVKEALSPIKFNRWGLPEVNPETMQTSEPWVFAGGDVVGMANTTVESVNDGKQASWYIHKHIQAQYGTSVPSQPTMPLFYTPVDLVDISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKSDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVRVPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTVSGLMGLKADGTPWPAVGIGRRTTYGGVSGTAIRPIALRAVTAIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYLKSIEELADWDGQSPPIISHQKGKPVPRVAELMGQK--LPSFGPYLEQRKKIIAASKIRQKDQNTACSPLQRKHFNSQKPIPAIKDVIGKSLQYLGTFGEMSIMEQVVALIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTV-SDTCTGCTLCLSVCPIMDCIRMVSRATPYQPKRGLPL 1019          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|81861573|sp|O89000.1|DPYD_RAT (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase)

HSP 1 Score: 1397.88 bits (3617), Expect = 0.000e+0
Identity = 668/1029 (64.92%), Postives = 813/1029 (79.01%), Query Frame = 0

Query:    9 SGCVSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKP--LPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDL 1035
            +G +S D PDIE+++ALNP+I+ +A    ++  K +KKHWKRN DK     +C  C + L  NFDDIKHTTL ER ALRE+ RCLKC DAPCQKSCPT LD+KSFI SI+ KNYYG+AK I SDNPLGLTCGMVCPTSDLCVGGCNL A+EEGPINIGGLQ FA E+F+ M IPQ+  P +P P  +PE+Y AKI L G GPASISC +FLAR+GY+D+T++EK+EYVGGL+TSE+P +RLPYDVVNFE+++MKDLGVK+  G+ +   ++TL  L  E G KA FIGIG PEPKK  IF+ L++ QGF+TSKDFLP VAK SKPGMC C S LP + G VIVLGAGDTAFDCATSALRCGA+RVF+VFRKGF NIRAVPEEMELA+EEKCEFLPF++P +V+ + DG++  +   RTEQ + G W  DEEQ ++ K D +IS FGS L    + ++L+P+K NRWG PEV+   M TSE W F GGD+ G A T VE+VNDGK A+W +H Y+Q  +   +P +P LP FYTP+D VD+SVEM GL+F NPFGLASA PAT+ PMIRR FEAGWGF +TKTFSLDKDIVTNV+PRI+RGTTSG  YGPGQ SFLNIELI+EKTAAYWC  + E+K DFP +++IASIMCSY+K DW EL+KMAEA+GADALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR  ++VPFFAKLTPNVT+IV IA AAKEGGADG TA NTVSGLMG  + G  WPSVG  K+TTYGG+SG  +RP+ALRAV+AIA+ALPGFPILATGGIDSA+  LQFL +GASV+QV SAIQNQDFTV++DY TGLK LLYL+SI+EL +WDGQSPPT    KGKPV ++ +++G    LP+FGPY ++++  LA +K   +          R  +     IP++++VIG++L  +GT+ +L+  + VVALID EMCINCGKCYMTCND+GYQAI+FD ETH+P V +D CTGCTLC SVCPI++CI+MV R   Y+PKRG+ L
Sbjct:    2 AGVLSRDAPDIESILALNPRIQAHATLRSTMAKKLDKKHWKRNTDK-----NCFIC-EKLENNFDDIKHTTLGERGALREAVRCLKCADAPCQKSCPTSLDIKSFITSIANKNYYGAAKLIFSDNPLGLTCGMVCPTSDLCVGGCNLHATEEGPINIGGLQQFATEVFKAMNIPQIRSPLLPPPEHMPEAYSAKIALFGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSISTDEMTLSTLK-ENGYKAAFIGIGLPEPKKDHIFQGLTQVQGFYTSKDFLPLVAKGSKPGMCACHSPLPSVRGAVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFANIRAVPEEMELAKEEKCEFLPFLSPRKVIVK-DGKIVGMQFVRTEQDETGNWVEDEEQIVRLKADVVISPFGSVLDDPKVIEALSPIKFNRWGLPEVNPETMQTSEPWVFAGGDVVGMANTTVESVNDGKQASWYIHEYIQAQYGALVPSQPTLPLFYTPVDLVDISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKNDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQSVRVPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTVSGLMGLKADGSPWPSVGSGKRTTYGGVSGTTIRPIALRAVTAIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYLKSIEELSDWDGQSPPTMSHQKGKPVPHIAELMGQK--LPSFGPYLERRKKILAASKIRENDQNRACSPLQRKHFNSQKPIPAIKDVIGKSLQYLGTFGELNIMEQVVALIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTV-SDTCTGCTLCLSVCPIMDCIRMVSRATPYEPKRGLPL 1019          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|160332325|sp|Q12882.2|DPYD_HUMAN (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase; Flags: Precursor)

HSP 1 Score: 1387.47 bits (3590), Expect = 0.000e+0
Identity = 666/1029 (64.72%), Postives = 814/1029 (79.11%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKP--LPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAK---KERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDL 1035
            +S D+ DIE+++ALNP+ + +A    +   K +KKHWKRN DK     +C +C + L  NFDDIKHTTL ER ALRE+ RCLKC DAPCQKSCPT LD+KSFI SI+ KNYYG+AK I SDNPLGLTCGMVCPTSDLCVGGCNL A+EEGPINIGGLQ FA E+F+ M IPQ+  P +P P  + E+Y AKI L G GPASISC +FLAR+GY+D+T++EK+EYVGGL+TSE+P +RLPYDVVNFE+++MKDLGVK+  G+ L  +++TL  L  E G KA FIGIG PEP K  IF+ L++ QGF+TSKDFLP VAK SK GMC C S LP + G VIVLGAGDTAFDCATSALRCGA+RVF+VFRKGF NIRAVPEEMELA+EEKCEFLPF++P +V+ +  GR+  +   RTEQ + G W  DE+Q +  K D +ISAFGS L    +K++L+P+K NRWG PEVD   M TSEAW F GGD+ G A T VE+VNDGK A+W +H+Y+Q  +  ++  +P LP FYTPID VD+SVEM GLKFINPFGLASA PAT+  MIRR FEAGWGF +TKTFSLDKDIVTNV+PRI+RGTTSG  YGPGQ SFLNIELI+EKTAAYWC+ + E+K DFP +++IASIMCSY+K DW ELAK +E +GADALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR  +++PFFAKLTPNVT+IV IA AAKEGGA+G TA NTVSGLMG  S G  WP+VG+ K+TTYGG+SG A+RP+ALRAV++IA+ALPGFPILATGGIDSA+  LQFL +GASV+QV SAIQNQDFTV++DY TGLK LLYL+SI+EL +WDGQSP T    KGKPV  + +++  +K LP+FGPY +Q++  +A+ K   KE+++         R  + P   IP++++VIG+AL  +GT+ +L N + VVA+ID EMCINCGKCYMTCND+GYQAI+FD ETH+P +  D CTGCTLC SVCPI++CIKMV R   Y+PKRG+ L
Sbjct:    5 LSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDK-----NCFNC-EKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEKMSEAYSAKIALFGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSVNEMTLSTLK-EKGYKAAFIGIGLPEPNKDAIFQGLTQDQGFYTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKG-GRIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVISAFGSVLSDPKVKEALSPIKFNRWGLPEVDPETMQTSEAWVFAGGDVVGLANTTVESVNDGKQASWYIHKYVQSQYGASVSAKPELPLFYTPIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGLKSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYLKSIEELQDWDGQSPATVSHQKGKPVPRIAELM--DKKLPSFGPYLEQRKKIIAENKIRLKEQNVAFS---PLKRNCFIPKRPIPTIKDVIGKALQYLGTFGELSNVEQVVAMIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTI-TDTCTGCTLCLSVCPIVDCIKMVSRTTPYEPKRGVPL 1019          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|75041534|sp|Q5R895.1|DPYD_PONAB (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase)

HSP 1 Score: 1380.16 bits (3571), Expect = 0.000e+0
Identity = 663/1029 (64.43%), Postives = 811/1029 (78.81%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKP--LPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAK---KERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDL 1035
            +S D+ DIE+++ALNP+ + +A    +   K +KKHWKRN DK     +C +C + L  NFDDIKHTTL ER ALRE+ RCLKC DAPCQKSCPT LD+KSFI SI+ KNYYG+AK I SDNPLGLTCGMVCPT DLCVGGCNL A+EEGPINIGGLQ FA E+F+ M IPQ+  P +P P  + E+Y AKI L G GPASISC +FLAR+GY+D+T++EK+EYVGGL+TSE+P +RLPYDVVNFE+++MKDLGVK+  G+ L  +++TL  L  E G KA FIGIG PEP K  IF+ L++ QGF+TSKDFLP VAK SK GMC C S LP + G VIVLGAGDTAFDCATSALRCGA+RVF+VFRKGF NIRAVPEEMELA+EEKCEFLPF++P +V+ +  GR+  +   RTEQ + G W  DE+Q +  K D +ISAFGS L    +K++++P+K NRWG PEVD   M TSEAW F GGD+ G A T VE+VNDGK A+W +H+Y+Q  +  ++  +P LP FYT ID VD+SVEM GLKFINPFGLASA PAT+  MIRR FEAGWGF +TKTFSLDKDIVTNV+PRIVRGTTSG  YGPGQ SFLNIELI+EKTAAYWC+ + E+K DFP +++IASIMCSY+K DW ELAK +E +GADALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR  +++PFFAKLTPNVT+IV IA AAKEGGA+G TA NTVSGLMG  S G  WP+VG+ K+TTYGG+SG A+RP+ALRAV++ A+ALPGFPILATGGIDSA+  LQFL +GASV+QV SAIQNQDFTV++DY TGLK LLYL+SI+EL +WDGQSP T    KGKPV  + +++  +K LP+FGPY +Q++  +A+ K   KE++I         R  + P   +P++++VIG+AL  +GT+ +L N + VVA+ID EMCINCGKCYMTCND+GYQAI+FD ETH+P +  D CTGCTLC SVCPI++CIKMV R   Y+PKRG+ L
Sbjct:    5 LSKDSADIESILALNPRTQTHATLRSTSAKKLDKKHWKRNPDK-----NCFNC-EKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTPDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIPQIRNPFLPPPEKMSEAYSAKIALFGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSVNEMTLSTLK-EKGYKAAFIGIGLPEPNKDAIFQGLTQDQGFYTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKG-GRIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVISAFGSVLSDPKVKEAMSPIKFNRWGLPEVDPETMQTSEAWVFAGGDVVGLANTTVESVNDGKQASWYIHKYIQSQYGASVSAKPELPLFYTAIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGLKSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSTARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYLKSIEELQDWDGQSPATVSHQKGKPVPRIAELM--DKKLPSFGPYLEQRKKIIAENKIRLKEQNIASSPH---KRNCFIPKRPVPTIKDVIGKALQYLGTFGELSNVEQVVAMIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTI-TDTCTGCTLCLSVCPIVDCIKMVSRTTPYEPKRGVPL 1019          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|2498309|sp|Q28007.1|DPYD_BOVIN (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase)

HSP 1 Score: 1376.3 bits (3561), Expect = 0.000e+0
Identity = 664/1026 (64.72%), Postives = 801/1026 (78.07%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKP--LPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDL 1035
            +S D  DIE+++ALNP+ +  A    ++  K +KKHWKRN DK     +C +C + L  NFDDIKHTTL ER ALRE+ RCLKC DAPCQKSCPT LD+KSFI SIS KNYYG+AK I SDNPLGLTCGMVCPTSDLCVGGCNL A+EEGPINIGGLQ +A E+F+ M IPQ+  P +P P  +PE+Y AKI LLG GPASISC +FLAR+GYND+T++EK+EYVGG++TSE+P +RLPYDVVNFE+++MKDLGVK+  G+ L  +D+TL  L  E G KA FIGIG PEPKK  IF+ L++ QGF+TSKDFLP VAK+SK GMC C S L  + G VIVLGAGDTAFDCATSALRCGA+RVF+VFRKGF NIRAVPEE+ELAREEKCEFLPF++P +V+ +  GR+  +   RTEQ + G W  D +Q    K D +ISAFGS L    +K++L+P+K NRW  PEVD   M TSE W F GGD+ G A T VEAVNDGK A+W +HRY+Q  +  ++  +P LP FYTPID VD+SVEM  LKF NPFGLASA P T+  MIRR FEAGW F +TKTFSLDKDIVTNV+PRI+RGTTSG  YGPGQ SFLNIELI+EKTAAYWC+ + E+K DFP +++IASIMCSY++ DW EL++ AEA+GADALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR  +++PFFAKLTPNVT+IV IA AAKEGGA+G TA NTVSGLMG  + G  WP+VG EK+TTYGG+SG A+RP+ALRAV+ IA+ALP FPILATGGIDSA+  LQFL  GASV+QV SAIQNQDFT++ DY TGLK LLYL+SI+EL +WDGQSP T    KGKPV  + +++G  K LP+FGPY ++ +  +A+ K          +   R  + P   IPSV++VIG+AL  +GTY +L+N + VVA+ID EMCINCGKCYMTCND+GYQAI+FD ETH+P V  D CTGCTLC SVCPII+CIKMV R   Y+PKRG+ L
Sbjct:    5 LSKDVADIESILALNPRTQSRATLRSTLAKKLDKKHWKRNPDK-----NCFNC-EKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSISNKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQYATEVFKAMNIPQIRNPSLPPPEKMPEAYSAKIALLGAGPASISCASFLARLGYNDITIFEKQEYVGGISTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSVNDITLSTLKEE-GYKAAFIGIGLPEPKKDHIFQGLTQDQGFYTSKDFLPLVAKSSKAGMCACHSPLLSIRGTVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFVNIRAVPEEVELAREEKCEFLPFLSPRKVIVKG-GRIVAMQFVRTEQDETGKWNEDGDQIACLKADVVISAFGSVLSDPKVKEALSPIKFNRWDLPEVDPETMQTSEPWVFAGGDVVGIANTTVEAVNDGKQASWYIHRYIQSQYGASVSAKPELPLFYTPIDLVDISVEMAALKFTNPFGLASATPTTSSSMIRRAFEAGWAFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNRNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVRIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGLKADGTPWPAVGREKRTTYGGVSGTAIRPIALRAVTTIARALPEFPILATGGIDSAESGLQFLHGGASVLQVCSAIQNQDFTIIQDYCTGLKALLYLKSIEELQDWDGQSPATKSHQKGKPVPCIAELVG--KKLPSFGPYLEKCKKIIAEEKLRLKKENVTVLPLERNHFIPKKPIPSVKDVIGKALQYLGTYGELNNTEQVVAVIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTV-TDTCTGCTLCLSVCPIIDCIKMVSRTTPYEPKRGLPL 1019          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|2498311|sp|Q28943.1|DPYD_PIG (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase; Flags: Precursor)

HSP 1 Score: 1373.22 bits (3553), Expect = 0.000e+0
Identity = 662/1026 (64.52%), Postives = 804/1026 (78.36%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVP--KPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDL 1035
            +S D  DIE+++ALNP+ + +A    ++  K +KKHWKRN DK     +C  C + L  NF DIKHTTL ER ALRE+ RCLKC DAPCQKSCPT LD+KSFI SIS KNYYG+AK I SDNPLGLTCGMVCPTSDLCVGGCNL A+EEG INIGGLQ FA E+F+ M IPQ+  P +P  + +PE+Y AKI LLG GPASISC +FLAR+GY+D+T++EK+EYVGGL+TSE+P +RLPYDVVNFE+++MKDLGVK+  G+ L ++++TL  L  E G KA FIGIG PEPK   IF+ L++ QGF+TSKDFLP VAK+SK GMC C S LP + G VIVLGAGDTAFDCATSALRCGA+RVF+VFRKGF NIRAVPEE+ELA+EEKCEFLPF++P +V+ +  GR+  +   RTEQ + G W  DE+Q +  K D +ISAFGS L    +K++L+P+K NRW  PEVD   M TSE W F GGD+ G A T VE+VNDGK A+W +H+Y+Q  +  ++  +P LP FYTP+D VD+SVEM GLKFINPFGLASA P T+  MIRR FEAGWGF +TKTFSLDKDIVTNV+PRIVRGTTSG  YGPGQ SFLNIELI+EKTAAYWC+ + E+K DFP +++IASIMCSY+K DW EL++ AEA+GADALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR  +++PFFAKLTPNVT+IV IA AAKEGGADG TA NTVSGLMG  + G  WP+VG  K+TTYGG+SG A+RP+ALRAV+ IA+ALPGFPILATGGIDSA+  LQFL +GASV+QV SA+QNQDFTV+ DY TGLK LLYL+SI+EL  WDGQSP T    KGKPV  + +++G  K LPNFGPY +Q++  +A+ K              R  + P   IP++++VIG+AL  +GT+ +L N + VVA+ID EMCINCGKCYMTCND+GYQAI+FD ETH+P V  D CTGCTLC SVCPII+CI+MV R   Y+PKRG+ L
Sbjct:    5 LSKDVADIESILALNPRTQSHAALHSTLAKKLDKKHWKRNPDK-----NCFHC-EKLENNFGDIKHTTLGERGALREAMRCLKCADAPCQKSCPTHLDIKSFITSISNKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGSINIGGLQQFASEVFKAMNIPQIRNPCLPSQEKMPEAYSAKIALLGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSENEITLNTLKEE-GYKAAFIGIGLPEPKTDDIFQGLTQDQGFYTSKDFLPLVAKSSKAGMCACHSPLPSIRGAVIVLGAGDTAFDCATSALRCGARRVFLVFRKGFVNIRAVPEEVELAKEEKCEFLPFLSPRKVIVKG-GRIVAVQFVRTEQDETGKWNEDEDQIVHLKADVVISAFGSVLRDPKVKEALSPIKFNRWDLPEVDPETMQTSEPWVFAGGDIVGMANTTVESVNDGKQASWYIHKYIQAQYGASVSAKPELPLFYTPVDLVDISVEMAGLKFINPFGLASAAPTTSSSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTVSGLMGLKADGTPWPAVGAGKRTTYGGVSGTAIRPIALRAVTTIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAVQNQDFTVIQDYCTGLKALLYLKSIEELQGWDGQSPGTESHQKGKPVPRIAELMG--KKLPNFGPYLEQRKKIIAEEKMRLKEQNAAFPPLERKPFIPKKPIPAIKDVIGKALQYLGTFGELSNIEQVVAVIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTV-TDTCTGCTLCLSVCPIIDCIRMVSRTTPYEPKRGLPL 1019          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|97536128|sp|Q18164.2|DPYD_CAEEL (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase)

HSP 1 Score: 1304.66 bits (3375), Expect = 0.000e+0
Identity = 640/1043 (61.36%), Postives = 792/1043 (75.93%), Query Frame = 0

Query:    1 MPPNPNDESGC-----VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGS-CSDTLFKN-FDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCK-SGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVH-TYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQ-PKRGI 1033
            M P PN  S       +S D+PDIE+L+ LNPK++  ANAVPS VTKKNK +WKRN +K      CGS C ++  KN F DIKHTTLSER AL+E+ RCLKC DAPCQKSCPTQLDVKSFI SIS KNYYG+A+ ILSDNPLGLTCGM+CPTSDLCVG CNL ASEEG INIGGLQ +A ++F++M + Q++  +V +    S+K ++ L+GCGPASISC +FLAR+GY D+T+YEK  Y+GGL+++E+P +RLPYDVV+FE+ + +D+GV++ET R LG+  LTL KL  E G  AVFIGIGNPEPK  P+FE L+   GF+TSK++LP VA ASKPGMC CK + LP + G V+VLGAGDTA DCATSALRCGA RV + FRKGFT IRAVPEEME A+EEKCEFLPF AP ++  + DGR+  +   +TEQ D+G W+ DEEQ +  KCD++ISAFGS L  + +  +L P +LN+WG  EVDS    TSE W F GGD+AG AET VE+VNDGKIAAW+MHRY+Q LH   + E P LP+F+TPID+VD+SV+MCG+KF NPFGLASAPP T+ PM RR FE GWGF++TKT+ LDKD+VTNV+PRIVRG+TSG  YGP QGSF+NIELI+EK+  YW + I E+K D P  ++IASIMC Y+K DW ELA  +E AGAD LELNLSCPHGMGE+GMGLACGQ   +VK IC+WVRA +K+PFF K+TPN+T++  IA AA++GGA G TA NTVS LM   + G AWP++G  K+TTYGGMSG+A+RP+A++AVS+IA  L GFPI+ATGGI+SA+  L FL AGASV+QV SA+QNQDFTVVDDY TGLK LLYL   + L  WDGQSPP  +  KGKP+     ++   K +P FG Y  +++   A    E ++L     H   RP  + S ++P+VE+VIG+AL  IG Y  LDN++  VA+ID +MCINCGKCYMTCND+GYQAI FD  TH P V  D CTGCTLCYSVCPI ECI+MVPR   ++ PKRG+
Sbjct:    1 MTPKPNTTSPTNNLPLLSKDSPDIESLLILNPKVQDKANAVPSAVTKKNKHNWKRNEEKG-----CGSTCGESKLKNDFRDIKHTTLSERGALKEAMRCLKCADAPCQKSCPTQLDVKSFITSISNKNYYGAARQILSDNPLGLTCGMICPTSDLCVGSCNLQASEEGAINIGGLQQYACDVFKQMNVRQIVSKEVRENRNASHKEQVALIGCGPASISCASFLARLGYTDITIYEKRAYIGGLSSAEIPQFRLPYDVVDFEIQLARDIGVQIETNRPLGKDGLTLAKLK-EQGAAAVFIGIGNPEPKIDPLFEGLTIENGFYTSKNYLPAVAAASKPGMCGCKRTPLPTMRGRVVVLGAGDTAMDCATSALRCGASRVTIAFRKGFTGIRAVPEEMEAAKEEKCEFLPFSAPRKINVK-DGRIVSIEFNKTEQDDNGKWYEDEEQIVILKCDYVISAFGSTLKEDAVLSALQPCQLNKWGGIEVDSTTQQTSEKWVFAGGDVAGVAETTVESVNDGKIAAWNMHRYIQSLHGNQVSETPELPQFFTPIDEVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVRGSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVIASIMCVYNKADWIELATKSEEAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPNITDVREIARAARDGGASGVTATNTVSSLMHMKADGNAWPAIGSTKRTTYGGMSGSAIRPIAMKAVSSIANELDGFPIMATGGIESAETGLGFLMAGASVLQVCSAVQNQDFTVVDDYCTGLKALLYLSGAESLKNWDGQSPPIEKHQKGKPI-----LLQGQKKMPFFGKYRDEREKLEAIKLSESNLLDTENYHFASRPDTQVS-RVPTVEDVIGKALPRIGPYVTLDNQEQKVAIIDDDMCINCGKCYMTCNDSGYQAITFDPVTHQPHVTEDDCTGCTLCYSVCPIPECIEMVPRTGPWKAPKRGV 1030          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|221272036|sp|A8XKG6.2|DPYD_CAEBR (RecName: Full=Probable dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase)

HSP 1 Score: 1277.69 bits (3305), Expect = 0.000e+0
Identity = 631/1045 (60.38%), Postives = 788/1045 (75.41%), Query Frame = 0

Query:    4 NPNDESGCVSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCG-SCSDTLFKN-FDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCK-SGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGK----------IAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVH-TYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQ-PKRGI 1033
            NPN     +S D+PDIE+L+ LNPK++  ANAVPS VTKKNK +WKRN +K      CG SC ++  KN F DIKHTTLSER AL+E+ RCLKC DAPCQKSCPTQLD+KSFI SIS KNYYG+A++ILSDNPLGLTCGM+CPTSDLCVG CNL ASEEG INIGGLQ +A ++F++M + Q++  +V +    S+K +I L+GCGPASISC +FLAR+GY D+T+YEK  Y+GGL+++E+P +RLPYDVV+FE+ + +D+GVK+ET R L + D+TL+KL  + G  AVFIGIGNPEPK  P+FE L+   GF+TSK++LP VA ASKPGMC CK + LP + G V+VLGAGDTA DCATSALRCGA RV + FRKGFT IRAVPEEME A+EEKCEFLPF AP ++  + DGR+  +   +TEQ D+G W+ DEEQ +  KCD++ISAFGS L  + +  +L P KLN+WG  EVDS    TSEAW F GGD+AG AET VE+VNDGK          IAAW+MHRY+Q  H   + E P LPKF+TPID+VD+SV+MCG+KF NPFGLASAPP T+ PM RR FE GWGF++TKT+ LDKD+VTNV+PRIVRG+TSG  YGP QGSF+NIELI+EK+  YW + I E+K D P  +++ASIMC Y+KEDW ELA  +EAAGAD LELNLSCPHGMGE+GMGLACGQ   +VK IC+WVRA +K+PFF K+TPN+T++  IA AA++GGA G TA NTVS LM   + G AWP++G  K+TTYGGMSG+A+RP+A++AVS+IA  L GFPI+ATGGI+SA+  L FL AGASV+QV SA+QNQDFTVV+DY TGLK LLYL   + L EWDGQSPP  +  KGKP+     ++   K +P FG +  +++   A    E ++L  +  H   RP  + + ++P+VE+VI                +H VA+ID +MCINCGKCYMTCND+GYQAI FDA TH P V  D CTGCTLCYSVCPI ECI+MVPR+  ++ PKRG+
Sbjct:    9 NPNVGLPLLSKDSPDIESLLILNPKVQSKANAVPSAVTKKNKHNWKRNEEKG-----CGASCGESKLKNDFRDIKHTTLSERGALKEAMRCLKCADAPCQKSCPTQLDIKSFITSISNKNYYGAARAILSDNPLGLTCGMICPTSDLCVGSCNLQASEEGAINIGGLQQYACDVFKQMNVRQIVSKEVRENRNASHKEQIALIGCGPASISCASFLARLGYTDITIYEKRAYIGGLSSAEIPQFRLPYDVVDFEIQLARDVGVKIETNRSLCKEDITLDKLKSQ-GAAAVFIGIGNPEPKIDPLFEGLTIENGFYTSKNYLPAVAAASKPGMCGCKRTPLPTMRGRVVVLGAGDTAMDCATSALRCGASRVTIAFRKGFTGIRAVPEEMEAAKEEKCEFLPFSAPRKINVK-DGRIVSIEFNKTEQDDNGKWYEDEEQIVILKCDYVISAFGSTLKEDTVLSALQPCKLNKWGGIEVDSTTQQTSEAWVFAGGDVAGVAETTVESVNDGKTLMDLTFKIQIAAWNMHRYIQAKHGNVLGETPELPKFFTPIDEVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVRGSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVVASIMCVYNKEDWIELATKSEAAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPNITDVREIARAARDGGASGVTATNTVSSLMHMKADGNAWPAIGNTKRTTYGGMSGSAIRPIAMKAVSSIANELDGFPIMATGGIESAETGLGFLMAGASVLQVCSAVQNQDFTVVEDYCTGLKALLYLSGAESLKEWDGQSPPVEKHQKGKPI-----LLQGQKNMPFFGKFRDEREKLEALKLSESNLLDTDNYHFASRPDTQVA-RVPTVEDVI----------------EHEVAIIDHDMCINCGKCYMTCNDSGYQAITFDAVTHQPHVTEDDCTGCTLCYSVCPIPECIQMVPRKGPWKAPKRGV 1024          

BLAST of dihydropyrimidine dehydrogenase vs. SwissProt
Match: gi|74859332|sp|Q55FT1.1|DPYD_DICDI (RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrothymine dehydrogenase; AltName: Full=Dihydrouracil dehydrogenase)

HSP 1 Score: 1274.23 bits (3296), Expect = 0.000e+0
Identity = 627/1023 (61.29%), Postives = 783/1023 (76.54%), Query Frame = 0

Query:   18 DIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVP--KPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEA-WAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPE-EPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSN---KPLPNFGPYAKQKQLALAKAKKERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGI 1033
            DIE ++ALNP +  +A   P++V+KK+K++W R       ++ C    + L  +F+D+K TTL+ER AL ES RCLKC DAPCQK CPTQLD+KSFI SISTKNYYG+AK+I SDNPLGLTCGMVCP S LC  GCNL A+EEGPINIGGLQ FA E+F+KM IPQ+  P +     LPESYKAKI L+GCGP SISC TFL R+GY DVT++EKE+Y+GGL++SE+P+YRL Y+VV FE+ +MKDLGVKVE G+ LG++  T+E L  + G +A+++GIG PEPK  P+F  L+  QGFF+SK+FLPKV+KASK GMC CKS LP+L G VIVLGAGDTAFDCATSA RCGA RV V FR+GF+++RAVPEE+++A++E+CEFLP++ P +V+ R DG+V  +   +TE+ DDG +  DE+Q  + KCD+IISAFGS + S  + +S +P++ N+WGT ++D + MT+  A W FCGGDL G   T VEAVNDGK A+W++H+YLQ LH I IP+  P LP F+TPID VD+SVEMCG+KF NPFGLASA PAT+  MIRR FE GWGF VTKTFSLDKD+VTNV+PRIVRGTTSGH +GPGQG+FLNIELI+EKT  YWCK IGE+K DFP  ++IASIMC ++KEDW +LAKMAEA+GAD +ELNLSCPHGMGE+GMGLACGQD  LV +ICQWVRA  ++PFFAKLTPNVT I  IA AA +GGADG TAINTVSGLMG      AWP++G EK+TTYGG+SGNA RP+ALRAVS+I K+LP +PI+ATGG DSAD T+QFL  GASV+Q+ S++QNQDFTVV DYITGLKT LY+QS ++L +WDGQSPP              ++I  N   K LP FG Y  ++     + K+  D+      +   P   P+  +PS+++ I RA+  IG ++DL   Q VVALID + CINCGKCYMTCND+GYQAI+FD +TH+P V  D CTGC LC SVCP+ +CI MVPRE +Y P RG+
Sbjct:   13 DIE-ILALNPTVNKHATFKPTIVSKKDKENWAR-------LDHCKKGCE-LKNDFEDVKPTTLTERGALFESARCLKCADAPCQKGCPTQLDIKSFISSISTKNYYGAAKTIFSDNPLGLTCGMVCPVSSLCQYGCNLAATEEGPINIGGLQQFATEVFKKMNIPQIRDPSLTPLSQLPESYKAKIALIGCGPTSISCATFLGRLGYTDVTIFEKEQYLGGLSSSEIPNYRLNYEVVEFEIKLMKDLGVKVEYGKRLGENGFTVESLQKQ-GYEAIYLGIGMPEPKIDPVFNELTSDQGFFSSKEFLPKVSKASKAGMCGCKSQLPQLNGRVIVLGAGDTAFDCATSAFRCGASRVTVCFRRGFSDMRAVPEEVDIAKDERCEFLPYVLPKQVIKR-DGKVVAMEFYKTEKGDDGNYSVDEDQFFRVKCDYIISAFGSQIGS--VAESCSPLQFNKWGTADIDPMTMTSKHAEWLFCGGDLVGNG-TTVEAVNDGKTASWNIHKYLQSLHGIPIPDGPPQLPNFFTPIDLVDISVEMCGMKFPNPFGLASATPATSAAMIRRSFEQGWGFAVTKTFSLDKDLVTNVSPRIVRGTTSGHHFGPGQGAFLNIELISEKTCHYWCKAIGELKRDFPDRIVIASIMCGFNKEDWTQLAKMAEASGADGIELNLSCPHGMGEKGMGLACGQDTELVFHICQWVRAATRLPFFAKLTPNVTEIKEIAKAAHDGGADGVTAINTVSGLMGLKGDSNAWPAIGDEKRTTYGGVSGNATRPIALRAVSSIRKSLPDYPIMATGGADSADATIQFLHCGASVVQICSSVQNQDFTVVQDYITGLKTYLYMQSREDLLQWDGQSPP-------------NEIINKNPKLKGLPKFGKYLLERNRIDTEEKQNIDL--QKVKNPLVPSPNPTHPVPSLKDQINRAIPRIGRHDDLKRDQQVVALIDEDKCINCGKCYMTCNDSGYQAIKFDGKTHIPLV-TDLCTGCDLCLSVCPVPDCITMVPRETIYVPDRGL 1005          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|291244574|ref|XP_002742170.1| (PREDICTED: dihydropyrimidine dehydrogenase [NADP(+)]-like [Saccoglossus kowalevskii])

HSP 1 Score: 1511.89 bits (3913), Expect = 0.000e+0
Identity = 722/1030 (70.10%), Postives = 849/1030 (82.43%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPK--PLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVHT-YRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDLDQS 1038
            +S DT DIE+L++LNP+   +A  VP+  TKKNKKHWKRN    +    CGSC DTL  NFDDIKHTTLSER ALRE+ RCLKC DAPCQKSCPTQLD+K+FI SI+TKNYYG+AK+I SDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FA EMFQKMRIPQ+  P +P    LPESY++KI L+GCGPASISC TFLAR+GY+++ VYEK+EYVGGL++SE+P +RLP+DVV+FEV+ MKDLGVKVE G+ LG + ++L+ L  E G K VFIGIG P+PK IPIF  L+   GF+TSK FLP VA ASK GMC+CKS LPE++GNVIVLGAGDTAFDCATSALRCGA+RVFVVFRKGFT IRAVPEEMELAREEKCEF+PF+AP +V+ + DGR++ L L RTEQ DDG+WF DEEQT++ K DFIISAFGS L  + +K +++P+K N+WG P+V+   M TSE W FCGGDLAG A+T VE+VNDGK AAW +H+YLQ+LH  ++P +P LPKFYTPID VD+SVE+CGLKF NPFGLASAPP TT  MIRRGFEAGW F +TKTFSLDKDIVTNV+PRIVRGTTSGH YGPGQGSFLNIELI+EKTAAYWC+ + E+K DF   +II+SIMCSY+KEDW +LAKMAE +GADALELNLSCPHGMGERGMGLACGQDA LV+NIC+WVRA +K+PFFAKLTPNVT+IVVIA AA EG ADG TA NTVSGLMG  S G AWP+VG EK TTYGG+SGNA+RP+ALRAVSAI +ALPGFPILATGGIDSAD  LQFL +GAS++QV SA+QNQDFTV++DYITGLKTL+YL+SIDEL +WDGQSPPT R   GKPV  L ++IG  K +PNFGPY +++   +A  K   D+L ++Q  +  RP Y+P   IP+V+E+IGRAL  IG Y DLDN Q  VA+ID EMCINCGKCYMTCND+GYQAI FD ETH+P +  D CTGCTLC SVCPI++CI M+PR+  +   RG+ L  S
Sbjct:    3 LSKDTADIESLLSLNPRTSQHAIVVPTAATKKNKKHWKRN----DTSKKCGSC-DTLKNNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQLDIKAFISSIATKNYYGAAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLFASEEGPINIGGLQQFATEMFQKMRIPQIRDPSLPALDDLPESYQSKISLIGCGPASISCATFLARLGYSNIVVYEKQEYVGGLSSSEIPQFRLPFDVVSFEVEQMKDLGVKVEFGKGLGINGMSLQSLK-ENGSKVVFIGIGMPQPKLIPIFHDLAMKHGFYTSKHFLPLVAAASKAGMCSCKSSLPEIHGNVIVLGAGDTAFDCATSALRCGARRVFVVFRKGFTTIRAVPEEMELAREEKCEFMPFVAPRKVLVK-DGRITGLELCRTEQQDDGSWFEDEEQTVRLKADFIISAFGSSLTDDIVKSAMSPIKFNKWGLPDVNHDTMQTSEEWVFCGGDLAGVAQTTVESVNDGKQAAWYIHQYLQKLHSASVPSKPQLPKFYTPIDSVDISVEVCGLKFSNPFGLASAPPTTTSAMIRRGFEAGWSFALTKTFSLDKDIVTNVSPRIVRGTTSGHVYGPGQGSFLNIELISEKTAAYWCQTVTELKADFKDKIIISSIMCSYNKEDWTKLAKMAEDSGADALELNLSCPHGMGERGMGLACGQDAELVRNICRWVRAAVKIPFFAKLTPNVTDIVVIAKAAYEGKADGVTATNTVSGLMGLKSNGTAWPAVGKEKLTTYGGVSGNAIRPIALRAVSAIGRALPGFPILATGGIDSADAGLQFLQSGASLLQVGSAVQNQDFTVIEDYITGLKTLMYLKSIDELSDWDGQSPPTLRHQLGKPVPKLNEIIG--KGIPNFGPYREKRAEIVAANKATIDLLAEDQKPSPQRPPYQPKKSIPTVKEMIGRALSKIGAYGDLDNTQQYVAIIDEEMCINCGKCYMTCNDSGYQAIVFDPETHLPRINAD-CTGCTLCVSVCPILDCITMIPRQIPHVINRGVPLSVS 1022          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|1242753094|ref|XP_022315388.1| (dihydropyrimidine dehydrogenase [NADP(+)]-like [Crassostrea virginica])

HSP 1 Score: 1496.49 bits (3873), Expect = 0.000e+0
Identity = 722/1045 (69.09%), Postives = 850/1045 (81.34%), Query Frame = 0

Query:    8 ESGCVSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVP--KPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGD-NQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDLDQSWKPRLPDLQLR 1049
            ES  VS D PDIENL+ALNPK+  YAN V S  TK+NKKHWKRNA K      C  C      NFDDIKHTTLSER ALRE+ RCLKC DAPCQKSCPTQLD+KSFI SI+ KNYYG+AK+I SDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FA E+F++M+IPQ+  P +P  + LP+SYKAK+ LLGCGPASISC TFLAR+GY ++T++EK +Y+GGL++SE+P YRLPY VV+FEV++ KDLGVKVE GR L  SD+T++KL  E G +AVF+GIG P+PKKIPIF  L E+ GF+TSKDFLPKV+ ASK GMC+CK+ LP+L G VIVLGAGDTAFDCATSALRCGAKRV+VVFRKGFTNIRAVPEEMELAREEKCEFLPF+AP +V+ + D  V  +   RTEQ DDG W  DEE+ ++ K ++IISAFGSGL   D+ ++++PVK+N+WG PEVDS  M TSE W FCGGDLAG A+T VE+VNDGK A+W +H+YLQ LH I IP +P LPKFY+PID VD+SVEMCGLKF NP+GLASA P T+  MIRR FEAGWGF +TKTFSLDKDIVTNV+PRIVRGTTSGH +GPGQGS+LNIELI+EKTAAYWC+ I E+K DFP+H++I SIMCSY+KEDW ELAKMAEAAG+DALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR  +K+PFFAKLTPNVT+IV IA AA EG ADG TA NTVSGLMG  + G AWP+VG   +TTYGG+SGNA+RP+ALRAV+AIA+ LPGFPILATGGIDSA+  LQFL  GA+V+QV SAI NQ++TVVDDYITGLKTLLYL+S++EL  WDGQSPPTA    GKPV+ ++D+IG N  LP+FGPY  ++Q    K  KE+D+L + N     RP   P   +P V++VIG AL  IGTY DL+N++ VVALID EMCINCGKCYMTCND+GYQAI+FDA+TH+P V +D CTGCTLC SVCPII+CI MVPR   Y PKRGI L  + K  +P + L 
Sbjct:    2 ESRMVSKDVPDIENLLALNPKVTKYANLVSSTETKENKKHWKRNAAKG-----CSDCPPRA-NNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQLDIKSFITSIANKNYYGAAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEIFKEMKIPQIRDPSMPPLETLPDSYKAKVALLGCGPASISCATFLARLGYTNLTIFEKHDYIGGLSSSEIPQYRLPYSVVDFEVELAKDLGVKVEKGRSLSTSDITVQKLKKE-GYEAVFLGIGMPDPKKIPIFAELKESMGFYTSKDFLPKVSAASKAGMCSCKTKLPQLSGKVIVLGAGDTAFDCATSALRCGAKRVYVVFRKGFTNIRAVPEEMELAREEKCEFLPFLAPRKVMMKND-VVMGMEFVRTEQDDDGNWVEDEEEIIRIKANYIISAFGSGLSDSDVVEAMSPVKMNKWGQPEVDSKTMQTSEPWVFCGGDLAGVAQTTVESVNDGKQASWHIHKYLQELHGIPIPSKPSLPKFYSPIDLVDISVEMCGLKFPNPYGLASATPTTSSTMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGHMFGPGQGSYLNIELISEKTAAYWCQSITELKRDFPEHIVIGSIMCSYNKEDWVELAKMAEAAGSDALELNLSCPHGMGERGMGLACGQDPELVRNICRWVREAVKIPFFAKLTPNVTSIVSIAKAAYEGNADGVTATNTVSGLMGLKNNGMAWPNVGKNHRTTYGGVSGNAIRPIALRAVTAIARELPGFPILATGGIDSAEAGLQFLQGGATVLQVCSAIHNQEYTVVDDYITGLKTLLYLRSVEELQNWDGQSPPTAPHQLGKPVLKVKDIIGEN--LPSFGPYLAKRQEVKDKLYKEKDLLSEKNMPEPQRPANAPKKPVPKVKDVIGLALSQIGTYGDLNNEEQVVALIDEEMCINCGKCYMTCNDSGYQAIKFDAQTHLPTVTDD-CTGCTLCLSVCPIIDCINMVPRTTPYIPKRGIPL-STGKNLMPGISLE 1034          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|676463861|ref|XP_009056737.1| (hypothetical protein LOTGIDRAFT_233044 [Lottia gigantea] >gi|556103944|gb|ESO92596.1| hypothetical protein LOTGIDRAFT_233044 [Lottia gigantea])

HSP 1 Score: 1484.16 bits (3841), Expect = 0.000e+0
Identity = 708/1034 (68.47%), Postives = 842/1034 (81.43%), Query Frame = 0

Query:    9 SGCVSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPK--PLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVV-TRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGD-NQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDLDQS 1038
            SG +S + PDIENL+ LNPK++ +A  VPS  TKKNKKHWKRN DK     SCG+  + L KNFDDIKHTTLSERAAL+E++RCLKC DAPCQKSCPTQLDVK FIG IS  NYYG+AK+I SDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FA E+F+ M++PQ+  P +P    LP +YK+KI LLGCGPASISC TFLAR+GY+D+T++EK +Y GGL++SE+P +RLP+ VV+FE+++MKDLGVK+E GR LG  DL+L  L    G KAVF+GIG P+ KKIPIF  L E QGFFTSK FLP V++ASK G+C CKS LP+L GNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAR EKCEFLPFM+P +V+   ++ ++S +   +TEQ DDG W  DEEQT++ K +++ISAFGSGL  ED+ K+L P+KLN+W  PE+D+  M TSE W +CGGD+AG A+T VE+VNDGK A+W +HRYLQ L  + IPE P LP F+TPID VD+SVE+CGLKF NPFGLASAPP T+  MIRR FE GWGF +TKT+SLDKDIVTNV+PRIV+GTTSGH YGPGQGSFLNIELI+EKTAAYWCK + E+K DFP  ++IASIMCSY +EDW +LAKM+EAAGADALELNLSCPHGMGERGMGLACGQDA LV+NIC+WVRA +K+PFFAKLTPNVT+IV IA AA EG ADG TA NTVSGLMG      AWP++G E +TTYGG+SGNA+RP+ALRAVSAIA+ LPGFPILATGGID+AD  LQFL AGAS +QV SAIQNQDFTVV+DYI+GLKTLLYL+S+ EL+ W GQSPPT +   GKPV  ++D+IG +  LPNFG Y ++++  LAK K + D+L D  +    RP Y P+T +  V++VIG+AL  IG+Y DLDNKQ VVAL+D +MCINCGKCYMTCND+GYQAI FD  TH+P V  D CTGCTLC SVCPII+CI MV R+  Y+P+RGI L+ +
Sbjct:    3 SGKLSKEVPDIENLLNLNPKVRHHAQMVPSATTKKNKKHWKRNDDK-----SCGTKCEPLTKNFDDIKHTTLSERAALKEASRCLKCADAPCQKSCPTQLDVKYFIGCISNMNYYGAAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEIFKSMKVPQIRDPSLPAIDKLPATYKSKIALLGCGPASISCATFLARLGYSDITIFEKNQYNGGLSSSEIPQFRLPFSVVDFEIELMKDLGVKIERGRALGSKDLSLTSLKSN-GYKAVFVGIGLPDAKKIPIFADLKEEQGFFTSKTFLPVVSQASKAGLCACKSQLPQLTGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELARVEKCEFLPFMSPRKVLLNNSNNKISGMEFVKTEQDDDGNWIEDEEQTVRLKANYVISAFGSGLVDEDVIKALEPIKLNKWKLPEIDNNTMVTSEPWVYCGGDIAGVAQTTVESVNDGKCASWFIHRYLQNLDGVKIPEAPCLPNFFTPIDTVDISVEICGLKFPNPFGLASAPPTTSSAMIRRAFEQGWGFALTKTYSLDKDIVTNVSPRIVKGTTSGHLYGPGQGSFLNIELISEKTAAYWCKSVTELKQDFPDKIVIASIMCSYSQEDWTDLAKMSEAAGADALELNLSCPHGMGERGMGLACGQDAELVRNICRWVRAAVKIPFFAKLTPNVTSIVTIAKAAYEGKADGVTATNTVSGLMGIRPDATAWPNIGKEHRTTYGGLSGNAIRPIALRAVSAIARELPGFPILATGGIDAADSGLQFLLAGASALQVCSAIQNQDFTVVEDYISGLKTLLYLKSVKELNGWSGQSPPTPKHQLGKPVPKIKDIIGED--LPNFGEYKEKRKEVLAKNKVKIDLLDDIYKPEPVRPAYTPNTSVLHVQDVIGKALPMIGSYGDLDNKQQVVALVDDDMCINCGKCYMTCNDSGYQAITFDPLTHLPHVTED-CTGCTLCVSVCPIIDCITMVKRDTPYEPRRGIPLNTT 1027          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|260821394|ref|XP_002606018.1| (hypothetical protein BRAFLDRAFT_129513 [Branchiostoma floridae] >gi|229291355|gb|EEN62028.1| hypothetical protein BRAFLDRAFT_129513 [Branchiostoma floridae])

HSP 1 Score: 1481.08 bits (3833), Expect = 0.000e+0
Identity = 713/1037 (68.76%), Postives = 846/1037 (81.58%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVP--KPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLG-QSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGD-NQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDLDQSWKPRLP 1044
            +S D PDIEN++ALNP+I  +A    S VTK +KKHWKRN DK    NSCGS +  L KNFDDIKHTTLSER ALRE+ RCLKC DAPCQKSCPTQLD+K+FI SISTKNYYGSAK+I SDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FA E F  M+IPQ+  P +P    LPESY+AK+ L+GCGPASISC TFLAR+GY D+T++E++ ++GGL++SE+P +RLPY VV FEVD MKDLGVK+  G+ LG +   TL+ L  E G +AVF+GIG P+ K+  +F+ L+  QGF+TSKD+LP V+ ASKPGMC+CKS LP+L GNVIVLGAGDTAFDCATSALRCGA+RVF+VFRKGFT IRAVPEEMELAREEKCEF+PF +P +VV + +GR++ +   RTEQADDGTW  DE+Q +K K D+IISAFGS L    +  +L+PVKLN+WG PEVD+  M TSE W FCGGDLAG A+T VE VNDGK A+W +H+YLQ LH + +P EP LPKFYTPID VDLSVE+CG++F NPFGLASAPP T+ PMIRR FE GWGF +TKTF+LDKDIVTNV+PRIV+GTTSG+ YGPGQGSFLNIELI+EKTAAYWC+ + E+K DFP  ++IASIMCSY+K+DW ELA+MAE AG+DALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR+ IK+PFFAK+TPN+T++ VIA AAKEG ADG TA NTVSGLMG  S  +AWP+VG E +TTYGG+SGNA+RP+ALRAVSAIA+ALPGFPILATGGIDSA+  LQFL  GASV+QV SAIQNQDFTVV+DYITGLK +LYLQS+D+L +WDGQSPPT R  KGKP V + DVIG  K LP+FGPY  Q++  +AK  +  +IL + N     RP   P   +PS+++VIGRAL +I +Y+ LDNKQ  VALID EMCINCGKCYMTCND+GYQAI FDAETH+P V +D CTGCTLC SVCPII+CI+MVPR   Y PKRGI L  + +P+ P
Sbjct:    7 LSRDPPDIENILALNPRISQHATLKSSKVTKAHKKHWKRNGDKG--CNSCGSAN--LTKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQLDIKTFISSISTKNYYGSAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLFASEEGPINIGGLQQFATETFMAMKIPQIRDPSLPLLDDLPESYQAKVALIGCGPASISCATFLARLGYTDLTIFERDNHIGGLSSSEIPQFRLPYSVVAFEVDQMKDLGVKIVCGKALGGEGGWTLQSLK-EAGYEAVFLGIGLPQAKRASMFQGLTVEQGFYTSKDYLPLVSAASKPGMCSCKSQLPQLSGNVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFTTIRAVPEEMELAREEKCEFMPFHSPRKVVLK-NGRIAGMEFCRTEQADDGTWHVDEDQVVKLKADYIISAFGSTLSEPQVVSALSPVKLNQWGLPEVDTETMQTSEPWVFCGGDLAGVAQTTVECVNDGKQASWHLHKYLQSLHGLFVPSEPALPKFYTPIDQVDLSVEVCGIRFPNPFGLASAPPTTSAPMIRRAFEVGWGFALTKTFALDKDIVTNVSPRIVKGTTSGYHYGPGQGSFLNIELISEKTAAYWCQTVTELKRDFPDKIVIASIMCSYNKDDWIELAQMAEKAGSDALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRSAIKIPFFAKMTPNITDVTVIAQAAKEGMADGVTATNTVSGLMGLKSNARAWPAVGQEMRTTYGGVSGNAIRPIALRAVSAIARALPGFPILATGGIDSAEAGLQFLHCGASVLQVCSAIQNQDFTVVEDYITGLKAMLYLQSLDDLADWDGQSPPTFRHQKGKP-VKVADVIG--KHLPSFGPYMAQREEIIAKHHETSEILAEQNMPQPQRPARVPDKPVPSLQDVIGRALSTITSYSQLDNKQQAVALIDEEMCINCGKCYMTCNDSGYQAITFDAETHLPHVTDD-CTGCTLCVSVCPIIDCIQMVPRSIPYIPKRGIPL--AMEPQAP 1031          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|321459596|gb|EFX70648.1| (hypothetical protein DAPPUDRAFT_202177 [Daphnia pulex])

HSP 1 Score: 1479.54 bits (3829), Expect = 0.000e+0
Identity = 732/1036 (70.66%), Postives = 847/1036 (81.76%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDV-PKPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHH--INIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDN-QVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDLDQSWKPRL 1043
            +S D  DIEN++ALNPKIKP+A+ VPS  TKK KKHWKRN DK  N  SCG     LF+NFDDIKHTTLSERAA+RE+ RCLKC DAPCQKSCPTQLDVKSFIGSISTKNYYG+AK+I SDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FA EMF+ M+IPQ+LPPDV    L   Y++KI LLGCGPASISC TFLARMGY+D+T++EK E +GGL++SE+P YRLPY+VV+FE+++MKDLGVK+E G+ L  +D+TL+ L  + G + VFIGIG P+ K+IPIFE LSE  GF+TSKDFLPKV+ ASKPGMC CKS LP L+GNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGF N+RAVPEEM LA EEKCEF+PF+AP EV+ + D RV+ L   RTEQ DDGTW  DEEQ ++ K D+IISAFGSGL + D+K ++AP+K NRWG PEVD+  M +S  W FCGGD+AG AET VE+VNDGK AAW MH+Y+Q+  H  + I  EP LPKFYTPID VD+ VEMCGLKF NPFGLASAPP TT  MIRRGFEAGWGF +TKTFSLDKDIVTNV+PRIVRGTTSGH YGPGQGSFLNIELI+EKTAAYWC+ + E+K DFP H++IASIMCSY++ DW ELA+MA AAGADALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVRA + +PFFAKLTPNVT+IV IA AA EG ADG TA NTVSGLMG  S G AWPS+G E+KTTYGGMSGNA+RP+AL+AVSAIA+ALPGFPILATGGIDSAD  LQFL  GASV+Q+ S++QNQDFTVVDDYITGLKTL+YL+SID L  WDGQSPPT R   GKPV  L  ++  ++ LPNFGP+ K+++  +A+ KK  D+L +  Q    RP  +P+  +P +  +I  A+D IGTY DLDNKQ VVA+ID EMCINCGKCYMTCND+GYQAI FD  TH+P V  D CTGCTLC SVCPII+CI MVPR+  Y PKRG+ L      RL
Sbjct:    6 LSRDVADIENILALNPKIKPFASLVPSAETKKIKKHWKRNGDK--NCQSCGP--PDLFQNFDDIKHTTLSERAAVREAARCLKCADAPCQKSCPTQLDVKSFIGSISTKNYYGAAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEMFKLMKIPQILPPDVIVDELGPGYRSKIALLGCGPASISCATFLARMGYSDLTIFEKNETIGGLSSSEIPQYRLPYEVVDFEIELMKDLGVKIERGKSLSLADITLQGLK-DQGYQGVFIGIGLPQAKRIPIFENLSEQMGFYTSKDFLPKVSVASKPGMCKCKSALPSLHGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFNNVRAVPEEMGLAIEEKCEFMPFLAPKEVIVKGD-RVAGLKFLRTEQLDDGTWIEDEEQEVRLKADWIISAFGSGLENADVKAAMAPIKFNRWGLPEVDTRTMQSSLDWVFCGGDIAGVAETTVESVNDGKTAAWYMHQYIQQSSHGSLLISSEPKLPKFYTPIDLVDIGVEMCGLKFPNPFGLASAPPTTTSAMIRRGFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGHIYGPGQGSFLNIELISEKTAAYWCQSVTELKADFPNHILIASIMCSYNEADWTELARMAAAAGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRAAVTIPFFAKLTPNVTSIVAIARAAYEGQADGVTATNTVSGLMGVRSDGSAWPSIGKEQKTTYGGMSGNAIRPIALKAVSAIARALPGFPILATGGIDSADAALQFLQCGASVLQICSSVQNQDFTVVDDYITGLKTLMYLKSIDGLKGWDGQSPPTIRHQVGKPVTQLDTIV--DQHLPNFGPFMKEREKRVAEFKKAEDLLAEEYQPKPLRPANEPARPVPPIRAIIAAAIDRIGTYADLDNKQQVVAMIDEEMCINCGKCYMTCNDSGYQAIVFDPVTHLPKVNQD-CTGCTLCLSVCPIIDCITMVPRKIPYIPKRGVALGADVNRRL 1032          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|156369958|ref|XP_001628240.1| (predicted protein [Nematostella vectensis] >gi|156215211|gb|EDO36177.1| predicted protein [Nematostella vectensis])

HSP 1 Score: 1475.3 bits (3818), Expect = 0.000e+0
Identity = 705/1016 (69.39%), Postives = 828/1016 (81.50%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVP--KPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLG-QSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILG-DNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPR 1023
            +S  +P+IENL++LNP I   AN VP+ VTKKNKKHWKRNADK     SCGSCS+   KNFDDIKHTTLSER AL+E+ RCLKCVDAPCQKSCPTQLD+K FI  I+ KN+YG+AK+I SDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FA E+F+ M++PQ+  PD+     LPESYK+KI L+GCGPASISC TFL R+GY ++T++EKE+++GGL+++E+P +RLPY VV+FEV +M DLGVKVETGR LG  S LT++ L  + G K +F+G+G P+PKK  +FE LSE  GF+TSK FLP V+  SKPGMC CKS LP+L  NVIVLGAGDTAFDC TSALRCGA+RVFVVFRKGFTNIRAVPEEM+LA +EKCEFLPFM+P +V  + DG++  +   RTEQ DDGTW  D EQT+K K  F+ISAFGS L +ED+K++LAP+K N+WG PEV +  M TS    FCGGDLAG A T VE+VNDGK AAW MH++LQ LH + IP EP LP+F+TP+D VDLSVE+CG+KF NPFGLASAPP TT  MIRRGFEAGWGF +TKTFSLDKDIVTNV+PRIVRGTTSGH YGPGQGSFLNIELI+EKT+AYWC+ I E+K DFP  ++IASIMC Y K+DW  LAKMAEAAGADALELNLSCPHGMGERGMGLACGQDA LV+NIC+WVRA I +PFFAKLTPNVT+IVVIA AAKEG ADG TA NTVSGLMG     +AWP++G EK+TTYGGMSGNA+RP+ALRAVSAI +ALPGFPILATGGIDSAD  LQFL  GAS +QV SA+QNQDFTVVDDYI GLK L+Y++S+DE  +W+GQSPPT R  +GKPV  + D++G  K LP+FGPY  ++   +A  K+  DIL  + +    RP  K S   PSV++V+G ALD IGTY DLDN+Q VVALID EMCINCGKCYMTCND+GYQAI+FD ETH+P V +D CTGCTLC SVCPII+CIKMV R
Sbjct:    3 LSTHSPEIENLLSLNPSIPKKANIVPTAVTKKNKKHWKRNADK-----SCGSCSEAFIKNFDDIKHTTLSERGALKEAGRCLKCVDAPCQKSCPTQLDIKYFISCIANKNFYGAAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEIFKNMKLPQIRDPDLTPVDQLPESYKSKIALIGCGPASISCATFLGRLGYTNLTIFEKEKFIGGLSSAEIPQFRLPYSVVDFEVKLMMDLGVKVETGRGLGVSSGLTIQSLKND-GYKGIFLGMGLPQPKKFHVFEGLSEQNGFYTSKSFLPVVSSGSKPGMCACKSSLPQLSDNVIVLGAGDTAFDCCTSALRCGARRVFVVFRKGFTNIRAVPEEMQLAVDEKCEFLPFMSPKQVHVK-DGKIVAMEFFRTEQLDDGTWTEDAEQTLKIKATFVISAFGSTLSNEDVKQALAPIKFNKWGLPEVSAETMATSAEGVFCGGDLAGIANTTVESVNDGKQAAWFMHQHLQSLHVLTIPSEPALPRFFTPVDQVDLSVEICGIKFPNPFGLASAPPTTTSAMIRRGFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGHLYGPGQGSFLNIELISEKTSAYWCRSITELKKDFPDKILIASIMCGYSKQDWTTLAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAELVRNICRWVRAAITIPFFAKLTPNVTDIVVIARAAKEGNADGVTATNTVSGLMGLKGTSEAWPAIGREKRTTYGGMSGNAIRPIALRAVSAIGRALPGFPILATGGIDSADAALQFLHCGASALQVCSAVQNQDFTVVDDYINGLKCLMYMKSVDEYADWEGQSPPTPRHQQGKPVPKIADLVG--KGLPSFGPYLVKRNEIIAAHKRSSDILSKEYEPEPVRPAVKQSKPTPSVKDVVGLALDRIGTYGDLDNRQQVVALIDEEMCINCGKCYMTCNDSGYQAIKFDPETHLPTVTDD-CTGCTLCLSVCPIIDCIKMVQR 1008          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|443734974|gb|ELU18829.1| (hypothetical protein CAPTEDRAFT_161594 [Capitella teleta])

HSP 1 Score: 1472.6 bits (3811), Expect = 0.000e+0
Identity = 706/1025 (68.88%), Postives = 847/1025 (82.63%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVPKP--LPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFL-GQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGI 1033
            VS D  DIE++++LNP+IKP+AN   S  TKK+KKHWKRN D+A     C +C + L +NFDDIKHTTLSER AL+ES RCLKC DAPCQKSCPTQLDVKSFI SIS KNYYGSAK+ILSDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FAVE F++MRIPQ+  P +PK   LPE+Y+AKI ++GCGPASISC TFLAR+GY+D+TV+E+  +VGGL++SE+P +RLPYDVVN+EV++MKDLGVK+E G+ L     LTL+ L    G +AVF+GIG P+PKK+P+F+ L+E  GF+TSKDFLPKV+ ASKPGMC+CKS LP L G V+VLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEF+PFMAP ++ T+ +  +S +   RTEQ D+G W  D+EQ ++ K DF+ISAFGSGL  +++ ++L P+KLNRWG P+VD  +MTTSE W F GGD+AG A+T VE+VNDGK A+W MH+YLQ L  + +P+   LPKF+TPID+VD+S+ MCG++F NPFGLASAPP TT  MIRR FEAGWGF +TKTFSLDKD+VTNV+PRIVRGTTSG  +GPGQGSFLNIELI+EKTAA+WCKG+ E+K DFP  V+IASIM S++K+DW ELA MAEA+GADALELNLSCPHGMGERGMG+ACGQD  LV NIC+WVRA +K+PFFAKLTPNVTN+ VIA AAK+GGADG TA NTVSG+MG    G AWP++G EK+TTYGGMSGNA+RP+ALRAVSAI  ALPG+PILATGGID A+V +QFL+AGASV+QV SA+QNQD+T++DDYITGLK LLYLQS+ EL  WDGQSPPT     GKPV  ++D++G +  LPNFGPY ++K   +A+ KK  DIL D++    R    P   IPSV++++G+AL  IG YNDLDN+Q VVALID +MCINCGKCYMTCND+GYQA+EFD ETH+P V ND CTGCTLC SVCPII+CI+MV R   Y+PKRGI
Sbjct:    4 VSKDVDDIESILSLNPRIKPFANHKASAQTKKDKKHWKRNVDQA-----CTTC-EPLVQNFDDIKHTTLSERGALKESARCLKCADAPCQKSCPTQLDVKSFITSISNKNYYGSAKAILSDNPLGLTCGMVCPTSDLCVGGCNLYASEEGPINIGGLQQFAVEGFKEMRIPQIRDPSLPKKSELPETYRAKIAMIGCGPASISCATFLARLGYSDITVFERRPFVGGLSSSEIPQFRLPYDVVNWEVELMKDLGVKIECGKSLDSNGGLTLQGLR-NSGYQAVFLGIGLPDPKKLPLFQDLTEQMGFYTSKDFLPKVSAASKPGMCSCKSKLPNLSGTVVVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFMPFMAPYKIHTK-NNHISAMEFFRTEQDDNGQWVEDKEQMIRLKADFVISAFGSGLTEKNVVEALEPLKLNRWGLPDVDPTQMTTSEPWVFSGGDIAGVAQTTVESVNDGKTASWYMHKYLQSLGKLEVPKIATLPKFFTPIDNVDVSITMCGIRFENPFGLASAPPTTTPAMIRRAFEAGWGFALTKTFSLDKDLVTNVSPRIVRGTTSGQVFGPGQGSFLNIELISEKTAAFWCKGVKELKRDFPTKVVIASIMSSFNKDDWTELAIMAEASGADALELNLSCPHGMGERGMGMACGQDPNLVLNICRWVRAAVKIPFFAKLTPNVTNVTVIAKAAKDGGADGVTATNTVSGMMGLKQDGAAWPNIGKEKRTTYGGMSGNAIRPIALRAVSAIGNALPGYPILATGGIDCAEVGMQFLYAGASVLQVCSAVQNQDYTLIDDYITGLKCLLYLQSL-ELAGWDGQSPPTPAHQLGKPVPAVKDIVGQS--LPNFGPYLQKKNELIAQQKKGADILEDHK-PPMRNVLVPQKPIPSVQDMVGKALARIGAYNDLDNQQQVVALIDEDMCINCGKCYMTCNDSGYQAVEFDPETHLPKV-NDNCTGCTLCLSVCPIIDCIRMVTRTTPYKPKRGI 1015          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|1126198612|ref|XP_019632535.1| (PREDICTED: dihydropyrimidine dehydrogenase [NADP(+)]-like [Branchiostoma belcheri])

HSP 1 Score: 1468.37 bits (3800), Expect = 0.000e+0
Identity = 706/1028 (68.68%), Postives = 837/1028 (81.42%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVP--KPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLG-QSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGD-NQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDL 1035
            +S D PDIEN++ALNP++  +A    S VTK +KKHWKRN +K    +SCGS +  L KNFDDIKHTTLSER ALRE+ RCLKC DAPCQKSCPTQLD+K+FI SISTKNYYGSAK+I SDNPLGLTCGMVCPTSDLCVGGCNL ASEEGPINIGGLQ FA E F  M+IPQ+  P +P    LPESY+AK+ L+GCGPAS+SC TFLAR+GY D+T+YEK +Y+GGL++SE+P +RLPY+VV FEVD MKDLGVK+  G+ LG +   TL+ L  E G +AVF+GIG P+ K+  IF+ L+  QGF+TSKD+LP VA ASKPGMC+CKS LP+L GNVIVLGAGDTAFDCATSALRCGA+RVF+VFRKGFT IRAVPEEMELAREEKCEF+PF +P +VV + +GR++ +   RTEQ D+G W  DEEQ +K K D+IISAFGS L   ++  +L+PVKLN+WG PEVD   M TS  W FCGGDLAG A+T VE VNDGK A+W +H+YLQ LH + +P EP LPKFYTPID VDLSV+MCG++F NPFGLASAPP T+ PMIRR FEAGWGF +TKTF+LDKDIVTNV+PRIV+GTTSG+ YGPGQGSFLNIELI+EKTAAYWC+ + E+K DFP  ++IASIMCSY+K+DW ELA+MAE AG+DALELNLSCPHGMGERGMGLACGQD  LV+NIC+WVR+ IK+PFFAK+TPN+T++ VIA AAKEG ADG TA NTVSGLMG  +  +AWP+VG E +TTYGG+SGNA+RP+ALRAVSAIA+ALPGFPILATGGIDSA+  LQFL  GASV+QV SA+QNQDFTVV+DYITGLK +LYLQS+D+L +WDGQSPPT R  KGKP V + DVIG  K LP+FGPY  Q++  +AK  +  +IL + N     RP   P   +P+V++VIGRAL +I +Y+ LDNKQ  VALID EMCINCGKCYMTCND+GYQAI FD ETH+P +  D CTGCTLC SVCPII+CI MVPR   Y PKRGI L
Sbjct:    7 LSKDPPDIENILALNPRVLHHATLKSSKVTKAHKKHWKRNGEKG--CHSCGSAN--LTKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQLDIKTFISSISTKNYYGSAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLFASEEGPINIGGLQQFATETFMAMKIPQIQDPSLPPLDELPESYQAKVALIGCGPASVSCATFLARLGYTDLTIYEKNDYIGGLSSSEIPQFRLPYNVVAFEVDQMKDLGVKIVCGKALGGEGGWTLQSLK-EAGYEAVFLGIGLPQAKRAAIFQDLTVEQGFYTSKDYLPLVAAASKPGMCSCKSQLPQLSGNVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFTTIRAVPEEMELAREEKCEFMPFHSPKKVVLK-NGRIAGMEFCRTEQDDEGNWTVDEEQVVKLKADYIISAFGSTLSEPEVVSALSPVKLNQWGLPEVDPETMQTSAPWVFCGGDLAGVAQTTVECVNDGKQASWHLHKYLQSLHGLFVPSEPALPKFYTPIDLVDLSVDMCGIRFPNPFGLASAPPTTSAPMIRRAFEAGWGFALTKTFALDKDIVTNVSPRIVKGTTSGYHYGPGQGSFLNIELISEKTAAYWCQTVTELKRDFPDKIVIASIMCSYNKDDWIELAQMAEKAGSDALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRSAIKIPFFAKMTPNITDVTVIAQAAKEGMADGVTATNTVSGLMGLKANARAWPAVGQEMRTTYGGVSGNAIRPIALRAVSAIARALPGFPILATGGIDSAEAGLQFLHCGASVLQVCSAVQNQDFTVVEDYITGLKAMLYLQSLDDLADWDGQSPPTLRHQKGKP-VKVTDVIG--KHLPSFGPYMSQREEIIAKHHETSEILAEQNMPEPQRPARVPDKPVPTVQDVIGRALSTITSYSQLDNKQQTVALIDEEMCINCGKCYMTCNDSGYQAITFDPETHLPHITED-CTGCTLCVSVCPIIDCITMVPRTVPYIPKRGIPL 1024          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|871249742|ref|XP_005103884.2| (PREDICTED: dihydropyrimidine dehydrogenase [NADP(+)]-like [Aplysia californica])

HSP 1 Score: 1467.98 bits (3799), Expect = 0.000e+0
Identity = 700/1032 (67.83%), Postives = 837/1032 (81.10%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSDTLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVP--KPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSG-LPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGD--NQVHTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDLDQS 1038
            +S D PDIENL++LNP+I+  A  VPS VTK  KKHWKRN ++     +C SC +TL +NFDDIKHTTLSER ALRE+ RCLKC DAPCQKSCPTQLD+K FIG I+ KNYYG+AK+ILSDNPLGLTCGMVCPTSDLCVGGCNLDA+EEGPINIGGLQ FA E+F+ MR+PQV  P +P    LP+SYKAK+ L+GCGPASISC TFLAR+GY+DVTVYEK+ Y GGL++SE+P YRLPY VV FEV++MKDLGV++ T R L +SDLT++ L  + G KA+F+GIG P+ KKI +F  L+   GF+TSK+FLP VA ASKPG+C+CK+  LP L GNVIVLGAGDTAFDCATSALRCGA+RVFVVFRKGFTNIRAVPEEMELAREEKCEFLPF++P EV    +GR++ +   RTEQ +DG W  D+EQ +  K DF+ISAFGSGL    +K++L+PVKLN WG P+VD+  M TSE   FCGGD+AG A+T VE+VNDGK+AAWSMHR+LQ   ++++P+EP LP F+TPID VD+SVE+CGLKF NPFGLASAPP TT PMIRR FEAGWGF +TKTF+LDKDIVTNV+PRIVRGTTSGH +GP QG+FLNIELI+EKTAAYWC+ + E+K DFP +++IASIMC+YD+ DW +LA+MAE AGADALELNLSCPHGMGERGMGLACGQD  LV+NIC WVR  + +PFFAKLTPNVT IV IA AAKEGGADG TA N+VSGLMG  + G AWPSVG +K TTYGG++GNA+RP+ALRAV+AIAKALPGFPILATGGIDSAD  LQFL  GASV+QV SA+QNQDFTV++DY+ GLKTLLYL+S D+   WDGQS P  +  KGK VV + D+IG  K LP+FGPY KQ++  +A  K++ D+L D  N       G K S +IP ++++IG A+  I +Y +LDN   VVALID +MCINCGKCYMTCND+GYQAI FD ETH+P V    CTGCTLC SVCPI+ECI+MVPR + Y P+RGI L+ S
Sbjct:    6 LSRDLPDIENLLSLNPRIRSNAKVVPSAVTKVAKKHWKRNTER-----NCSSC-NTLTRNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQLDIKFFIGCIANKNYYGAAKTILSDNPLGLTCGMVCPTSDLCVGGCNLDATEEGPINIGGLQQFATEVFKDMRVPQVRDPSLPPLDQLPDSYKAKVALVGCGPASISCATFLARLGYSDVTVYEKKSYTGGLSSSEIPQYRLPYSVVGFEVELMKDLGVQIVTNRSLDRSDLTVQSLRQQ-GYKAIFLGIGLPDAKKIDVFRDLTVENGFYTSKEFLPLVAVASKPGLCSCKTQQLPPLRGNVIVLGAGDTAFDCATSALRCGARRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFLSPTEVRVN-NGRITGMQFVRTEQTEDGQWVEDKEQMVTLKADFVISAFGSGLTDSSMKEALSPVKLNTWGLPDVDTTDMRTSEPDVFCGGDMAGVAQTTVESVNDGKVAAWSMHRFLQSQFNLSVPQEPALPNFFTPIDSVDVSVEVCGLKFPNPFGLASAPPTTTSPMIRRAFEAGWGFALTKTFALDKDIVTNVSPRIVRGTTSGHLFGPSQGAFLNIELISEKTAAYWCRSVFELKRDFPDNILIASIMCAYDEADWTKLAQMAENAGADALELNLSCPHGMGERGMGLACGQDPELVRNICAWVREAVSIPFFAKLTPNVTRIVSIAQAAKEGGADGVTATNSVSGLMGLRNDGSAWPSVGKQKLTTYGGVTGNAIRPIALRAVTAIAKALPGFPILATGGIDSADAGLQFLQGGASVLQVCSAVQNQDFTVIEDYLIGLKTLLYLRSRDQFANWDGQSKPVEKHQKGKIVVRVGDLIG--KSLPSFGPYQKQRETIIAGLKQKLDLLTDVENDEGKKTEGTKQSREIPKIQDLIGVAVPGITSYGELDNTDQVVALIDEDMCINCGKCYMTCNDSGYQAISFDPETHLPKVDEKTCTGCTLCVSVCPIVECIQMVPRSEPYVPRRGIPLNVS 1027          

BLAST of dihydropyrimidine dehydrogenase vs. nr
Match: gi|908497117|ref|XP_013060860.1| (PREDICTED: dihydropyrimidine dehydrogenase [NADP(+)]-like [Biomphalaria glabrata])

HSP 1 Score: 1452.57 bits (3759), Expect = 0.000e+0
Identity = 686/1029 (66.67%), Postives = 838/1029 (81.44%), Query Frame = 0

Query:   12 VSHDTPDIENLMALNPKIKPYANAVPSVVTKKNKKHWKRNADKAENVNSCGSCSD--TLFKNFDDIKHTTLSERAALRESNRCLKCVDAPCQKSCPTQLDVKSFIGSISTKNYYGSAKSILSDNPLGLTCGMVCPTSDLCVGGCNLDASEEGPINIGGLQHFAVEMFQKMRIPQVLPPDVP--KPLPESYKAKIGLLGCGPASISCGTFLARMGYNDVTVYEKEEYVGGLNTSELPSYRLPYDVVNFEVDMMKDLGVKVETGRFLGQSDLTLEKLHMEMGCKAVFIGIGNPEPKKIPIFEPLSEAQGFFTSKDFLPKVAKASKPGMCNCKSGLPELYGNVIVLGAGDTAFDCATSALRCGAKRVFVVFRKGFTNIRAVPEEMELAREEKCEFLPFMAPMEVVTRADGRVSHLVLARTEQADDGTWFTDEEQTMKKKCDFIISAFGSGLYSEDLKKSLAPVKLNRWGTPEVDSIKMTTSEAWAFCGGDLAGTAETAVEAVNDGKIAAWSMHRYLQRLHHINIPEEPMLPKFYTPIDDVDLSVEMCGLKFINPFGLASAPPATTWPMIRRGFEAGWGFVVTKTFSLDKDIVTNVAPRIVRGTTSGHSYGPGQGSFLNIELITEKTAAYWCKGIGEIKTDFPKHVIIASIMCSYDKEDWQELAKMAEAAGADALELNLSCPHGMGERGMGLACGQDAALVKNICQWVRAVIKVPFFAKLTPNVTNIVVIASAAKEGGADGCTAINTVSGLMGFNSKGKAWPSVGVEKKTTYGGMSGNAVRPMALRAVSAIAKALPGFPILATGGIDSADVTLQFLFAGASVMQVSSAIQNQDFTVVDDYITGLKTLLYLQSIDELDEWDGQSPPTARTYKGKPVVNLQDVIGSNKPLPNFGPYAKQKQLALAKAKKERDILGDNQV-HTYRPGYKPSTKIPSVEEVIGRALDSIGTYNDLDNKQHVVALIDPEMCINCGKCYMTCNDTGYQAIEFDAETHVPFVKNDACTGCTLCYSVCPIIECIKMVPREDLYQPKRGIDL 1035
            VS D PDIENL+ALNP+++ +A  VPS  TKK K HWKRN  K      C SC+    L+KNFDDIKHTTLSER AL+E+ RCLKC DAPCQKSCPTQLD+K FI  I+ KNYYG+AK+I SDNPLGL+CGMVCPTSDLCVGGCNLDA+EEGPINIGGLQ FA EMF++MR+PQ+  P +     LPESYK+KI L+GCGPASISC +FLAR+GY+D+T++EK+ Y+GGL++SE+P YRLP+ VV+FEV++MKDLGVKV + R L   DLT+  L  + G KA+F+G+G P+PKKI IF+ L++  GF+TSKDFLP V++ASK G+C+CKS LP+L+GNV+VLGAGDTAFDCATSALRCGAK+VFVVFRKGFTNIRAVPEE+ELA+EEKCEFLPF+AP +V+ + +G ++ +   RTEQ ++G W  DE+Q +K K DF+ISAFGSG+    LK+++ PVK+N+WG P+V+   MTTSE   FCGGDLAG A+T VE+VNDGK+A+W +HRYLQ L++++ PE P LP F+TPID VD+SVEMCGL+F NPFGLASA P T+ PMIRR FEAGWGF +TKTFSLDKDIVTNV+PRI+RGTTSG  +GPGQGS+LNIELI+EKTAAYWC+ I E+K DFP +++IASIMC+Y +EDW ELAKMAEAAGADALELNLSCPHGMGERGMGLACGQ   LV++IC WVR  + +PFFAKLTPNVTNIV IA+AA EG ADG TA NTVSGLMG  S G  WP VG +K+TTYGG+SGNA+RP+ALRAVS+IA +LPGFPILATGGIDSA+V LQF+ AGASV+QV SAI NQD+TV++DYI GLKTLLYL+SI     WDGQSPPT +  KGKPV+ + +++G  KPLP+FGPY KQ++  +A  KK+ D+L D+Q     RP       +P V ++IG+A+D I +Y++LDN   V+ALID +MCINCGKCYMTCND+GYQAI FD ETH+P V    CTGCTLC SVCPI++CIKMV RED Y P+RGI L
Sbjct:   14 VSRDLPDIENLLALNPRVRRHATVVPSDATKKGKGHWKRNDSK-----ECSSCTSESNLYKNFDDIKHTTLSERGALKEAARCLKCADAPCQKSCPTQLDIKFFISCIANKNYYGAAKTIFSDNPLGLSCGMVCPTSDLCVGGCNLDATEEGPINIGGLQQFATEMFKEMRVPQIRDPSLTPLDQLPESYKSKIALIGCGPASISCASFLARLGYSDITIFEKKSYLGGLSSSEIPQYRLPFSVVSFEVELMKDLGVKVISNRSLDPDDLTINSLRQQ-GFKAIFLGLGLPDPKKIEIFQELTQGHGFYTSKDFLPLVSQASKAGLCSCKSQLPDLHGNVVVLGAGDTAFDCATSALRCGAKKVFVVFRKGFTNIRAVPEEVELAKEEKCEFLPFLAPRKVLVK-NGHIASMEFLRTEQNENGDWIEDEDQVIKLKVDFVISAFGSGITDSRLKEAMNPVKINKWGLPDVNPETMTTSEPDVFCGGDLAGVAQTTVESVNDGKVASWFIHRYLQTLYNLSTPEIPNLPNFFTPIDLVDVSVEMCGLRFPNPFGLASATPTTSSPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGQLFGPGQGSYLNIELISEKTAAYWCQSITELKRDFPANIVIASIMCAYIEEDWVELAKMAEAAGADALELNLSCPHGMGERGMGLACGQKPELVRDICSWVRNAVNIPFFAKLTPNVTNIVDIATAAYEGKADGVTATNTVSGLMGLKSDGSPWPHVGKQKRTTYGGVSGNAIRPIALRAVSSIAISLPGFPILATGGIDSAEVGLQFIQAGASVLQVCSAIHNQDYTVIEDYILGLKTLLYLKSIGHFSSWDGQSPPTLKHQKGKPVLKVAELVG--KPLPSFGPYQKQREAIIAGLKKKLDLLEDDQKPPPIRPALSSEQPVPRVVDLIGKAVDKITSYSELDNTDQVIALIDEDMCINCGKCYMTCNDSGYQAISFDPETHLPRVNKKDCTGCTLCLSVCPIVDCIKMVSREDPYIPRRGIPL 1033