dna replication atp-dependent helicase nuclease dna2-like, maker-scaffold757_size101632-snap-gene-0.17 (gene) Tigriopus kingsejongensis

Overview
Namedna replication atp-dependent helicase nuclease dna2-like
Unique Namemaker-scaffold757_size101632-snap-gene-0.17
Typegene
OrganismTigriopus kingsejongensis (Tigriopus kingsejongensis)
Associated RNAi Experiments

Nothing found

Homology
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. L. salmonis genes
Match: EMLSAG00000003094 (supercontig:LSalAtl2s:LSalAtl2s173:343286:346696:-1 gene:EMLSAG00000003094 transcript:EMLSAT00000003094 description:"maker-LSalAtl2s173-snap-gene-3.31")

HSP 1 Score: 803.127 bits (2073), Expect = 0.000e+0
Identity = 447/978 (45.71%), Postives = 611/978 (62.47%), Query Frame = 0
Query:   78 YGRHEVLAVERLLSELQLELRPEGSSSEVVQCRLAGSWLHTR--VSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHP-PQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHLRPSTPDGSAWPALPEPINLKRACAQCPHLMTCAISQKLESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVTHLHTF-GRHSNSTETLMGVFQTGETVVLSSDTELALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLM-VALGKTILLTSYTHSAVDNILLKLRAHES-NFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTLIRSL--GSVHSIGVVAPYRAQVNLLRQKLDPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYL 1047
            + R EV  VE +  E+ +E      +S      L GSW+     +  GD+++VL      G   +++D  GL V+ PD+LVSGTSV       ++AV                                  +  Q+ E F  +L        + +L M+  ++ QEV P++PHI FF E+YV  +   PP  AF P  + AP  PP+ WPG VE + DIEENIWSPRLG+KGKVDLT++VKL  RD+ GR + IMPLELKTGRPSGSAEHRGQVIMYSM+M+ERR DPESGLLLYLRNSSL EV AGIHEMRGLVQLRN+LV+HL         +  LPEPINLK AC +CPHL+ C  S  +      E HAM  L+P +L HL + +L FF  W++M + E  E    S+ KDLW + P +R+    AL +L L+ ++D     H+F G  +N +      F  GET+++S+   +ALAQG +  +    I  +LD+ L +D   + + I+ +D+YEY  S A+ LVNLAKLM+D   +++LR+ +I ++ V F +GLPK++A  AKPIL++LN VQQ+AIFK LMA D + LKGMPGTGKTTLIVAL+RL+ + + K++LLTSYT++A DN+ LKL + +   F+RLGR SRI+P L     E Q++           +D+     +V TTCLGLNHPA+  R FDYCI+DEA QA LLS++G LFH + F+LVGDP+QL PVV+S +AR LGM  S+FS +E  +N + L +QYRMN+ I  CAN LTY G+L+CG+ +++   L   D +   + +W+  AL P L  S++F+DT +   E      G+TN  E  +   L+  +  G+ + IGV+APY+AQV+LLR+K +  +DVNTVDQFQGKDKD+I Y  TR     +   K  +   IL+D RRLNVAITRAK K I++G+  TL+ + P ++LLT  
Sbjct:  109 FNRQEVTQVEYVNREIIME------TSLGRTVILRGSWISNTPTICRGDIINVLNP-LIEGKTDVIDDLNGLFVIHPDNLVSGTSV-------KEAV----------------------------------SMVQINEVFSSILKTPQFILDMATLQMTSNELTQEVSPYMPHILFFIERYVKEKNVKPPEQAFAPISRKAPSLPPSKWPGSVESIKDIEENIWSPRLGLKGKVDLTLKVKLKTRDKRGRLNKIMPLELKTGRPSGSAEHRGQVIMYSMIMSERRDDPESGLLLYLRNSSLMEVNAGIHEMRGLVQLRNQLVSHLL-----NLNYKDLPEPINLKTACEKCPHLIACTAS--IGDQNFGESHAMHVLIPDSLKHLTKEELNFFDRWNKMISFETYENRSSSRQKDLWLKLPEERKKNNQALDNLTLIRENDMK---HSFRGDMANLSNP---PFAIGETILVSTKNAIALAQGTVYRIGTEVIEVILDRNLYKDQEWK-NCIFCIDKYEYVPSSAA-LVNLAKLMSDTEESKKLRSLIIDKRQVEFLQGLPKEVAINAKPILKTLNRVQQKAIFKTLMAKDNICLKGMPGTGKTTLIVALIRLLAMTMKKSVLLTSYTNTAXDNVXLKLLSFDDVGFIRLGRRSRINPRLYNHMFESQTE----------FEDKL----VVGTTCLGLNHPAITSRRFDYCILDEAGQASLLSSVGPLFHAKVFILVGDPEQLRPVVRSVQARSLGMSESIFSLMERENNVIPLTLQYRMNSRITECANFLTYKGELECGNTQVASNILK-EDHSHDSDPSWVKSALDPSLHQSIVFLDTGSRGVESRHGSYGITNTHECEIIEQLLNRIKGGNDYDIGVIAPYQAQVSLLRKKFN-GIDVNTVDQFQGKDKDIIFYSCTRCSSNIKDEAKSSES--ILNDERRLNVAITRAKMKIILVGNRDTLVNFKPFNKLLTLF 1005          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. L. salmonis genes
Match: EMLSAG00000009428 (supercontig:LSalAtl2s:LSalAtl2s600:488026:492190:-1 gene:EMLSAG00000009428 transcript:EMLSAT00000009428 description:"maker-LSalAtl2s600-snap-gene-3.46")

HSP 1 Score: 133.65 bits (335), Expect = 5.841e-32
Identity = 126/443 (28.44%), Postives = 195/443 (44.02%), Query Frame = 0
Query:  668 LKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFS----AEHQSQEGMASD-------SLEN----------------------MKDRFMTCPIVATTCLGLNH-----PAVQKRN-----FDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCL--EEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTL-----TLNDENRHLNVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTLIRSLGSV----HSIGVVAPYRAQVNLLRQKL--DPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPP-IHELLTYLGETGTV 1053
            + G PGTGKTT +V +V   V  G  +L  + ++ AVDN+L +L  ++   +R+G  +RI  DL+ +S     +   Q  +  D       +L+N                      +K+ F    ++ TT +  +        ++ +N     FD  ++DE SQA  LS   +L    K +L GD  QLPP V S  A   G   +L   L    P     L IQYRMN +IM  ++   Y  +L+ GS E+  + L       N+E   + +  +  A    + + V   D +N             N  EA L V+ +R L         I V+ PY  QV L+R +   D   +V +VD FQG++K+ ++    R+      G         L ++RRLNVA+TRAK    ++    TL K  P +   + YLGE G +
Sbjct:  170 IHGPPGTGKTTTVVEIVSQAVKSGCKVLCVAPSNVAVDNLLERLVKNKLKCVRIGHPARISADLQKYSLDALIDSSDQTQIVRDVRKDIDLALKNARKNRNEIKELRRECREREGKAIKEIFSRAQVILTTLVSSDSVSGPLKVLKNKNDTSYPFDLVVIDECSQALELSCWISLPQAPKAILSGDHCQLPPTVMSQEAISKGFANTLMERLVKSHPVAVRVLEIQYRMNNSIMNWSSKEFYESKLKAGSDEVGKRVLIDLPGIENNEETSVPIILIDTA-GXXMHEFVADGDEEN---------GSKGNEGEASLVVSHVRKLIDAGMNPSDIAVITPYNLQVELIRSQFSGDKRPEVRSVDGFQGQEKEAVILSLVRSNEKGNVG--------FLAESRRLNVAVTRAKRHLAVVCDSETLSKGDPFLKRFVEYLGEHGEI 594          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. L. salmonis genes
Match: EMLSAG00000003665 (supercontig:LSalAtl2s:LSalAtl2s19:264402:269259:-1 gene:EMLSAG00000003665 transcript:EMLSAT00000003665 description:"maker-LSalAtl2s19-snap-gene-2.18")

HSP 1 Score: 103.605 bits (257), Expect = 1.552e-22
Identity = 92/293 (31.40%), Postives = 125/293 (42.66%), Query Frame = 0
Query:  777 RNFDYCIVDEASQAQLLSALGTL-FHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALN-------IQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVAWLARALSPKLEDSVLF----VDTQNIPTEDVSDQSGLTNPKEALLAVTLIRSLGSV-------HSIGVVAPY---RAQVNLLRQKL-----------DPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMK 1036
            RNF  CIVDEASQ      L  L     K V+VGDP+QLP  V S +A++L    SLF+ L + S     N       IQYRM+  I    NH  Y G+L  G                   V+W +R       +S LF     D      E+ +++  + N KEA    TLI  +           +IGV+  Y   R  ++L  Q L              V V TVD FQG + D+I+    R+   K+  +          ++ RLNVA+TRAK    ++G   TL K
Sbjct: 1188 RNFSICIVDEASQCVEPEGLIPLKLGFSKLVMVGDPEQLPATVSSIKAKDLSYGQSLFNRLFKSSRNSDTNTSIHCLKIQYRMHGDIARWPNHYFYGGELTNG-------------------VSWTSR-------NSDLFPLKLFDLSWTKMEETNNEKSIFNTKEAKFVATLISEIKKEPHIIPGNKTIGVITFYSQQRKHLSLELQNLGIETSDGKRISKSAVTVCTVDGFQGSEXDIIVLSCVRS--SKQNDIHTSSSIGFTGESERLNVALTRAKYALYIVGDFQTLSK 1452          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. L. salmonis genes
Match: EMLSAG00000005015 (supercontig:LSalAtl2s:LSalAtl2s260:591600:598646:1 gene:EMLSAG00000005015 transcript:EMLSAT00000005015 description:"maker-LSalAtl2s260-augustus-gene-6.11")

HSP 1 Score: 102.449 bits (254), Expect = 3.117e-22
Identity = 117/476 (24.58%), Postives = 196/476 (41.18%), Query Frame = 0
Query:  627 VTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALV-RLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSR-----------IHPDLRVFSAEHQSQEGMASDSLE---------------NMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQA-QLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNR-VALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVA--WLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEAL----LAVTLIRSLGSVHSIGVVAPYRAQVNLLRQ----------KLDPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVP 1057
            V F   LP+  +A   P L  LN  Q  A+ + L       ++G PGTGKT     +V +L+   G  +L+ + +++A D +  K+       +RL   +R           +H  +R   ++ +  + +  ++ E               + ++      ++  TC+      +    F   ++DE+ QA +    +  +    + +LVGD  QL PVV   +A   G+  SLF  L     R   L +QYRM+  +    ++  Y G LQ G          ++ E+R LN+   W        + D  +F    +   E     +   N  EA          I++      IG++ PY  Q   L Q          KL    ++ +VD FQG++KD+I+    R+   +  G         L D RRLNVA+TRAK   I++G+   L K P  + LL +  + G +   P
Sbjct:  466 VIFRCQLPRHFSA---PNLPDLNRSQVYAVRRALQ-RPLSLIQGPPGTGKTVTSATIVYQLVKQRGGPVLVCAPSNTAXDQLTEKIHRTGLKCVRLCAKTREAIDSPVAHLALHNQIRNIDSDFRKLQQLKDETGELSKADEIRYRMLRKSSERNILKVADVICCTCIAAGDLRINHMRFASILIDESMQATEPECMVPVVLGANQLILVGDHCQLGPVVMCKKASLGGLSQSLFERLVMLGIRPFRLEVQYRMHPELSKFPSNFFYEGSLQNG----------VSGEDRKLNIDFPW-------PVPDKPMFFYVTSGQEEIAGSGTSYLNRTEAANVEKFTTRFIKAGVKPEQIGIITPYEGQRAYLVQYMQYQGSLNTKLYQECEIASVDAFQGREKDIIIISCVRSNDHQGIG--------FLADPRRLNVALTRAKYAVIVVGNPKVLSKQPLWNNLLHHYKDHGCLVEGP 912          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. L. salmonis genes
Match: EMLSAG00000004276 (supercontig:LSalAtl2s:LSalAtl2s224:316115:320975:1 gene:EMLSAG00000004276 transcript:EMLSAT00000004276 description:"maker-LSalAtl2s224-augustus-gene-3.17")

HSP 1 Score: 88.1965 bits (217), Expect = 6.586e-18
Identity = 118/443 (26.64%), Postives = 192/443 (43.34%), Query Frame = 0
Query:  648 LNPVQQRAIFKLLMAND----FVTLKGMPGTGKTTLIVALVRLMVALGKT--ILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSA--EHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQK--RNFDYCIVDEAS---QAQLLSALGTLFHCE-KFVLVGDPDQLPPVVQSSRARELGMDASL------FSCLEEPS-NRVALNI--------------QYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTLIRSLGSV-----HSIGVVAPYRAQVNLLR---QKLD-PNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTY 1046
            LNP Q++A+  +L        ++   G PGTGKT  ++  +  +  L K   IL+T+ +++A D +LL L A  S  ++ G + RI    R F    E+      +  + +   +  +   IV TTC   +  +  K  R F +  VDEA    +  +L+ L  +   E + VL GD  QL PV+ SS A+E G+  SL      F+ L  P  N+                    YR +  I+   + L Y  +L    P +S    +    +  LN            ED  +     +       D     N +EA   V  +R L S+       +G++ PYR QV+ ++   Q  D P   V +V++FQG+++ +IL  T R+    +T          + D +R NVA+TRAK   I++G+   L++     E + Y
Sbjct:  677 LNPEQKQAVRSILKGEARPIPYIIF-GPPGTGKTVTLLETILQIFILRKDSRILVTAPSNAACD-LLLNLLA-ASKKVKPGDVVRILGARRKFENIPEYLIPYYFSIKNEKETMEGVLKSRIVVTTCTSSSFFSRIKDFRRFTHVFVDEAGFVLEPDILTPLNFVDIEEGQIVLAGDEKQLSPVLSSSLAKEFGLAYSLIERLCSFNPLYAPDPNKFVTRFSDSYDSLLITKLVRNYRNHPAILKLPSKLFYHDEL---IPSVS-NNQSFKGYDILLN------------EDFPIVFHALDGEQRRDEDSPSWYNYQEAFQIVLYLRKLYSIPRISEDQVGIITPYRKQVDCIKSYIQSFDLPIPKVGSVEEFQGQERLIILLSTVRSSX-LDTPASTKHVLGFVGDEKRFNVALTRAKDLLIIVGNPKVLIQDSVWKEFIEY 1099          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. L. salmonis genes
Match: EMLSAG00000000606 (supercontig:LSalAtl2s:LSalAtl2s109:446994:450007:1 gene:EMLSAG00000000606 transcript:EMLSAT00000000606 description:"maker-LSalAtl2s109-augustus-gene-4.29")

HSP 1 Score: 85.8853 bits (211), Expect = 6.804e-18
Identity = 82/305 (26.89%), Postives = 137/305 (44.92%), Query Frame = 0
Query:  761 IVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEE--PSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVAWLARALSPKLEDSVLFVDT--------QNIPTEDVSD-QSGLTNPKEALLAVTLIR---SLG-SVHSIGVVAPYRAQVNLLRQKLDPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGET 1050
            I  TT    +    +K NFD   +DEA      ++L  +    + +L GD  QLPP+  +  +   G + S    L +  P+    L+IQYR N  I   ++   Y  +L+  S   ++  +TL D   H N          +L    +F+DT        Q+  +E ++D    + N  EA L   ++     LG S   I V+     + + LR     ++ + TVD FQGK+K++I+    R+ P  E G         L + RR+NV++TRA+   I++G   TL   P + +L+ +  + 
Sbjct:  106 IFVTTIASTSLDTYKKYNFDLVCIDEAGFVSQGNSLLHILRAPRIILCGDHCQLPPITFNPDSALEGYEISAMEKLTKLLPNCVSFLSIQYRSNQIISEWSSRYIYYNKLRTSS---TVANITLQDLIPHQN---------SELNRPFVFIDTKGQGYHEEQDEGSEFMTDADKSIVNLNEAFLVEIIVNKYIELGVSPKVISVLRSLIWKSDHLR-----DISIYTVDSFQGKEKEMIIISFVRSNPYGEIG--------FLRETRRINVSVTRARRCVIIVGDSETLCHDPALKDLVDFCSDN 385          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. L. salmonis genes
Match: EMLSAG00000010050 (supercontig:LSalAtl2s:LSalAtl2s662:147778:155854:1 gene:EMLSAG00000010050 transcript:EMLSAT00000010050 description:"maker-LSalAtl2s662-augustus-gene-1.18")

HSP 1 Score: 62.7734 bits (151), Expect = 3.275e-10
Identity = 81/311 (26.05%), Postives = 135/311 (43.41%), Query Frame = 0
Query:  761 IVATTCLGLNHPAVQKRNFDYCIVDEA---SQAQLLSALGTLFHCEKFVLVGDPDQLPPVV--QSSRARELGMDASLFSC----------LEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGS-PEISLKTLTLNDENRHLNVAWLARA--LSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTLIRSLGSVHSIGVVAPYRAQVNLLRQKLD--PNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETG 1051
            I++T+ +G     +  + F +   DEA   S+ + L A+    +    VL GD  QL PVV  Q++    + +   L +C             P     L   YR +  ++  ++ + Y G+L   S P +S+     N   R   V    R   + PK   S  F +T+    + ++++         LLA+  I    S  SIG+++PYR Q   +   +   P ++  + + FQG++KD+I+  T R+           K    L + +R NVAITRAK   I++G    L   P    L+ Y+ E G
Sbjct:  344 ILSTSVMGYVVSKMVGKLFTHVFYDEAGFSSEPECLLAIKPHLNHALIVLSGDHYQLGPVVLSQNTFGLTISLMERLMTCDPYYMRGSGHTYNPKYVTKLVDNYRSDFRLLKLSSEIFYDGELVARSLPCLSVTRARENMGYRFPFVFIDVRGDMVRPKNCKS-FFNNTEVEIVQKIANK---------LLAMDDI----SQKSIGLISPYRPQYMQMGSIMHYCPRMEYGSPELFQGREKDIIIISTARSS-------NNSKTLGFLTNFKRFNVAITRAKYLCIVVGDSKLLEMDPVWSSLVNYIKENG 633          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|82105075|sp|Q8QHA5.1|DNA2_XENLA (RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; AltName: Full=DNA replication ATP-dependent helicase-like homolog; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2)

HSP 1 Score: 588.956 bits (1517), Expect = 0.000e+0
Identity = 364/997 (36.51%), Postives = 556/997 (55.77%), Query Frame = 0
Query:  100 EGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNEL---VTHLRPSTPDGS---AWPALPEPINLKRACAQCPHLMTCA-----ISQKLESA-VPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHL---KLVAQSDRVTHLHTFGRHSNSTETLMGVFQTGETVVLSSDTE-LALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGL----PKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVA-LNIQYRMNATIMACANHLTYVGQLQCGSPEIS--------LKTLTLNDENRHLNVA-WLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTL----IRSLGSVHSIGVVAPYRAQVNLLRQKLD----PNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPE 1058
            EG   E+  C L   W+  ++  GD++H L    S  N + ++   G L++ PD L+SGTS+   + CLR++VL+E+FK  +  S+ M  GT++H++ Q        T S ++E     +      + +  L ++ A V  E++ +LP +  +   ++     P      +  +     P      +V E  DIEENIWSPR G+KGK+D+T RVK+H + +      IMPLELKTG+ S S EHR QV++Y+++  ERR DPE+GLLLYL+  ++  V     + R L+++RNEL   +T++   + +GS      +LP  I  ++AC  C  +  CA     + Q+ E+  +P E   M  +V K   HL E  L++F+ W  MC LEA     K   K++W  +  +RE     + +L     V     V +LH+F R S S         +G+ VV+S +   LAL+ G I  + +  I+ +LD++L + P    D ++ LD  E  G +  +L NL++LM +   +++LR  +I      F + L    P D   +   ILR LN  Q++A+ ++L++ D+  + GMPGTGKTT I  LVR++ A G ++LLTSYTHSAVDNILLKL+  +  FLRLGR  ++HPD++ FS E +  +  +  SL  +++ + + P+VATTC+G+NHP   +R FD+CIVDEASQ      LG LF  ++FVLVGD  QLPP+V+S+ ARELGM  SLF  LE     V  L +QYRMN+ IMA +N L Y G+L+C S  +S        +KTL L  E R    + W+   L P   + V F++T+ IP  +  ++ G++N  EA L   L    +++      IG++APYR Q+ ++    +      V+VNTVD++QG+DK VI+    R+    + G       D+L D RRLNVA+TRAK K IM+G  PTL ++  + +L+  L     +  +PE
Sbjct:   78 EGDDLEL--CILKDDWVALQIKPGDIIH-LEGNCSVDNTWTISRDTGYLILYPDLLISGTSIANGIRCLRRSVLSEKFKVCDKGSRQMLNGTMLHDIFQRATTCGF-TDSVLQELAHHTVHGPKYLKEMYQLKLNQADVMGEIQEYLPSLSKWATDFM---THPLNQQQINRTKSTAGDPTET--TKVSEFLDIEENIWSPRFGLKGKIDVTARVKIHQKSKAHLK--IMPLELKTGKESNSIEHRSQVVLYTLLSQERREDPEAGLLLYLKTGNMYTVPGNRLDRRELLKIRNELSYYLTNVLHKSDNGSKETTLASLPAMIADRQACKYCSQMRNCALYNRSVEQQTENCYIPPE---MIPVVQKETEHLTEDHLQYFRLWYLMCTLEANSKDSKMGRKNIWMMSSSEREEDGQCIGNLIRTGHVQTISDVQYLHSFQRRSGSVPATN--LASGDRVVVSGEERFLALSTGYIKEVKDENITCILDRSLVKLPE---DLLFRLDHEEGGGGLEFHLGNLSRLMENSSVSEKLRKLIIDFSKPNFVQHLSSILPPDAKDIVASILRGLNKPQKQAMKRVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLKKFQVGFLRLGRTQKLHPDVQEFS-EEEICKAKSIKSLSALEELYNSQPVVATTCMGVNHPIFTRRRFDFCIVDEASQISQPICLGPLFFADRFVLVGDHQQLPPLVKSAEARELGMSESLFKRLERNQEAVVQLTVQYRMNSKIMALSNKLVYEGRLECASDRVSNAVVQLPHIKTLLLELEFRESQESMWIKDVLEPS--NPVCFLNTEKIPALETEEKGGISNWIEAKLVFHLTKLYLKAGCRPSDIGIIAPYRQQLKMISNYFNSLSASAVEVNTVDKYQGRDKSVIIVSFVRSNIDGKLG-------DLLKDWRRLNVALTRAKHKLIMLGCVPTLNRFDCLEQLICNLKTENQIYDLPE 1045          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|408407614|sp|D3ZG52.1|DNA2_RAT (RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; AltName: Full=DNA replication ATP-dependent helicase-like homolog; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2)

HSP 1 Score: 581.637 bits (1498), Expect = 0.000e+0
Identity = 370/1021 (36.24%), Postives = 556/1021 (54.46%), Query Frame = 0
Query:   79 GRHEVLAVERLLSE-------LQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHL-----RPSTPDGSAWPALPEPINLKRACAQCPHLMTCAISQKLESAV--PAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVT---HLHTFGRHSNS--TETLMGVFQTGETVVLSSDTE--LALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTF----AKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLE-EPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEIS--------LKTLTLNDENRHLNVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAV----TLIRSLGSVHSIGVVAPYRAQV----NLLRQKLDPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVP 1057
             R+ VLAVE  L+E       L + +  EG     V C L   W    V  GD++H+  E       ++V+D  G  ++ PD L+SGTSV +S+ CLR+AVL+E F+  +  ++ M IGT++HE+ Q  ++         E   Q +     +++ +  L++S  +VR EVE +LP    + ++++        P              +     V +  DIEE+IWSPR G+KGK+D+TV VK+H RD   +   IMPLELKTG+ S S EHRGQVI+Y+++  ERR DPE+G LLYL+   +  V A   + R L++LRN+L   L     R +  + +   ALP+ I  ++ C  C  +  CA+  +    V   + P  M   + +   HL    LK+F  W  M  LE+Q    K   + +W     + E   + +  L       RV    +LH F R +       LM     G+ ++LS +     AL++G +  +D   ++ +LD+ L   P T    ++ LDR E  G + + L NL+KLM +   +++LR  +I  K   F    +  LP D       IL+ LN  Q++A+ K+L++ D+  + GMPGTGKTT I ALVR++ A G ++LLTSYTHSAVDNILLKL   +  FLRLG+  ++HPD++ F+ E   +    + SL ++++ + + P+VATTC+G++HP   ++ FD+CIVDEASQ      LG LF   +FVLVGD  QLPP+V +  AR LGM  SLF  LE   S  V L IQYRMN  IM+ +N LTY G+L+CGS  ++        LK + L     + +  WLA    P  ++ V F++T  +P  +  +  G++N  EA L V    T I++  S   IG++APYR Q+    +LL +     V+VNTVD++QG+DK +IL    R+    E G  G    ++L D RRLNVAITRAK K I++G   +L ++PP+ +L  +L     ++ +P
Sbjct:   46 NRYLVLAVETKLNERGAEEKHLLITVSQEGEQE--VLCILRNGWSSVPVEPGDIIHI--EGDCTSEPWIVDDDFGYFILSPDMLISGTSVASSIRCLRRAVLSETFRVSDTATRQMLIGTILHEVFQKAISESFAPEKLQELALQTLREVRHLKE-MYRLNLSQDEVRCEVEEYLPSFSKWADEFMHKGTKAEFPQMHLSLPSDSSDRSSPCNIEVVKSLDIEESIWSPRFGLKGKIDVTVGVKIH-RDCKTKYK-IMPLELKTGKESNSIEHRGQVILYTLLSQERREDPEAGWLLYLKTGQMYPVPANHLDKRELLKLRNQLAFSLLHRVSRAAAGEEARLLALPQIIEEEKTCKYCSQMGNCALYSRAVEQVHDTSIPEGMRSKIQEGTQHLTRAHLKYFSLWCLMLTLESQSKDTKKSHQSIWLTPASKLEESGNCIGSLVRTEPVKRVCDGHYLHNFQRKNGPMPATNLMA----GDRIILSGEERKLFALSKGYVKRIDTAAVTCLLDRNLSTLPETT---LFRLDREEKHGDINTPLGNLSKLMENTDSSKRLRELIIDFKEPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQSHKVHPDIQKFTEEEMCRLRSIA-SLAHLEELYNSHPVVATTCMGISHPMFSRKTFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHKQLPPLVLNREARALGMSESLFKRLERNESAVVQLTIQYRMNRKIMSLSNKLTYEGKLECGSDRVANAVITLPNLKDVRLEFYADYSDNPWLAGVFEP--DNPVCFLNTDKVPAPEQIENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGIIAPYRQQLRTITDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRS---NEDGTLG----ELLKDWRRLNVAITRAKHKLILLGSVSSLKRFPPLEKLFDHLNAEQLISNLP 1042          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|119368660|sp|Q6ZQJ5.2|DNA2_MOUSE (RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; AltName: Full=DNA replication ATP-dependent helicase-like homolog; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2)

HSP 1 Score: 573.548 bits (1477), Expect = 0.000e+0
Identity = 370/1029 (35.96%), Postives = 563/1029 (54.71%), Query Frame = 0
Query:   79 GRHEVLAVE-----RLLSELQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQT-----ILSLDMSLAQVRQEVEPFLPHIQFFTEKYVL-GQAAPPPPPAFH-PPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHL-----RPSTPDGSAWPALPEPINLKRACAQCPHLMTCAISQKL---ESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVT---HLHTFGRHSNS--TETLMGVFQTGETVVLSSDTE--LALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLI-HRKP---VTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLE-EPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTL-NDENRHLNVA---------WLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAV----TLIRSLGSVHSIGVVAPYRAQVNLLRQKLDPN----VDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVP 1057
             R+ VLAVE     R   E +L +         V C L   W    V  GD+VH+  E       ++++D  G  ++ PD ++SGTSV +S+ CLR+AVL+E F+G +  ++ M IGT++HE+ Q  ++      S   ER Q  LA   +R+      +  L++S  ++  EVE +LP    + E ++  G ++  P      P  G+    P      V +  DIEE+IWSPR G+KGK+D+TV VK+H   ++     +MPLELKTG+ S S EHR QV++Y+++  ERR DPE+G LLYL+   +  V A   + R L++LRN L   L     R +  + +   ALP+ I  ++ C  C  +  CA+  +    +    + P AM   + +   HL    LK+F  W  M  LE+Q    +   + +W     + E   + + +L       RV    +LH F R +       LM     G+ ++LS +     AL++G +  +++  ++ +LD+ L   P T    ++ LDR E  G +++ L NL+KLM     +++LR  +I  R+P      +  LP D       IL+ LN  Q++A+ ++L++ D+  + GMPGTGKTT I ALVR++ A G ++LLTSYTHSAVDNILLKL   +  FLRLG+  ++HPD++ F+ E   +    + SL ++++ + + PIVATTC+G+NHP   ++ FD+CIVDEASQ      LG LF   +FVLVGD  QLPP+V +  AR LGM  SLF  LE   S  V L +QYRMN  IM+ +N LTY G+L+CGS  ++   L L N ++  L++          WLA  L P  ++ V F++T  +P  +  +  G++N  EA L V    T I++  S   IGV+APYR Q+ ++   L  +    V+VNTVD++QG+DK +IL    R+    E G  G    ++L D RRLNVA+TRAK K I++G   +L ++PP+  L  +L     +  +P
Sbjct:   46 NRYLVLAVETSQNERGAEEKRLHVTASQDREHEVLCILRNGWSSVPVEPGDIVHL--EGDCTSEPWIIDDDFGYFILYPDMMISGTSVASSIRCLRRAVLSETFRGSDPATRQMLIGTILHEVFQKAISE-----SFAPERLQE-LALQTLREVRHLKEMYRLNLSQDEILCEVEEYLPSFSKWAEDFMRKGPSSEFPQMQLSLPSDGSNRSSPCNI--EVVKSLDIEESIWSPRFGLKGKIDVTVGVKIHRDCKMKYK--VMPLELKTGKESNSIEHRSQVVLYTLLSQERREDPEAGWLLYLKTGQMYPVPANHLDKRELLKLRNWLAASLLHRVSRAAPGEEARLSALPQIIEEEKTCKYCSQIGNCALYSRAVEEQGDDASIPEAMLSKIQEETRHLQLAHLKYFSLWCLMLTLESQSKDNRKTHQSIWLTPASELEESGNCVGNLVRTEPVSRVCDGQYLHNFQRKNGPMPATNLMA----GDRIILSGEERKLFALSKGYVKKMNKAAVTCLLDRNLSTLPAT---TVFRLDREERHGDISTPLGNLSKLMESTDPSKRLRELIIDFREPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKRVLLSKDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKVGFLRLGQSHKVHPDIQKFTEEEICRSRSIA-SLAHLEELYNSHPIVATTCMGINHPIFSRKTFDFCIVDEASQISQPVCLGPLFFSRRFVLVGDHQQLPPLVVNREARALGMSESLFKRLERNESAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKDARLSLQLYADYSDSPWLAGVLEP--DNPVCFLNTDKVPAPEQVENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGVIAPYRQQLRIISDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRS---NEDGTLG----ELLKDWRRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDHLNAEQLILDLP 1045          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|408360056|sp|Q5ZKG3.2|DNA2_CHICK (RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; AltName: Full=DNA replication ATP-dependent helicase-like homolog; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2)

HSP 1 Score: 572.007 bits (1473), Expect = 0.000e+0
Identity = 349/980 (35.61%), Postives = 542/980 (55.31%), Query Frame = 0
Query:  109 CRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHLRPSTPDG------SAWPALPEPINLKRACAQCPHLMTC-----AISQKLESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVT---HLHTFGRHSNSTETLMGVFQTGETVVLSSDTE--LALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGL----PKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVA-LNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLND------ENRHLNVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTLIRSLGSVHSIGVVAPYRAQVNL---LRQKLDPN-VDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVP 1057
            C L   W    V  GD+VH+  E   +   +++N++ G L++ PD L+SGT++ +S+ C+R+AVL+ERF+G E  S+   +GT++HE+ Q  + +++ +  +VEE  + ++      + +  L +   ++ QE+E +LP    +TE +V   A         P +       +     + ++ DIEENIWSPR G+KGK+D+T RVK+H +   G  S IMPLELK+G+ S S EHR QVI+Y+++  ERR DPE+G LLYL+  ++  V     + R L++LRN++  +L  ST         S   ALP  I+  +AC  C  +  C     A+ +++ S   + P A+  ++ K   HL    L++F  W  M  LE Q    K   K++W     +RE     + ++  V Q   V+   +LH+F R + +          G+ VV+S +    L LA G +  +   +IS +L + L + P +     + LD  E   S+     NL+KLM D P +++LR  +I      F + L    P +       IL+ LN  Q++A+ ++L++ D+  + GMPGTGKTT I ALVR++ A G ++LLTS+TH+AVDNILLKL   +  FLRLGR  ++HPD+R F+ E   +   +  S+ ++++ + + P+VAT C+G+NHP   ++ FD+CIVDEASQ      LG LF  ++FVLVGD  QLPP+VQ+S AR+LGM  SLF  LE+  N V  L +QYRMN+ IM+ +N L Y G+L+CGS ++S  T  L +      E    +  WL   L P  +  V F++T         +++G   P +                IG+++PYR Q+ +   L  +L  N V+VNT+D++QG+DK +I+    R    +  G        +L D RRLNVAITRAK K IM+G  P+L +YPP+ +LL +L     +  +P
Sbjct:   50 CVLQNGWESVPVVPGDIVHL--EGDCSSGTWVINEQSGYLILYPDLLLSGTTISSSIRCMRKAVLSERFRGSECGSRQTLVGTILHEIFQQSVTNNL-SPEKVEELAKKIVYGQKYLKEMYHLKLKQTEIMQEIEEYLPSFFKWTEDFVRNPANQNKMQLKLPSENKTGDCSSTV--EIVDILDIEENIWSPRFGLKGKIDVTARVKIHRQG--GIQSRIMPLELKSGKESNSVEHRSQVILYTLLNLERRVDPEAGFLLYLKTGTMYPVTGTRMDRRELIKLRNQVAFYLMHSTYKSAVGRQQSQLAALPPLIDDSQACKYCSQIHNCFLYSRAVEERMASV--SFPPALIPIIEKETQHLKPSHLEYFSLWYLMLTLEMQSGDSKKGYKNIWMIPSLEREKAGDCVGNMIRVDQVQEVSEGQYLHSFQRKNGAVPG--ANLLVGDRVVVSGEENGLLGLATGYVREISATKISCLLGRNLSKLPES---TTFRLDHEEGDCSIGVPFENLSKLMKDSPVSEKLRNLIIDFHKPRFIQHLSSVLPPEAKEAVASILKGLNKPQKQAMKQVLLSRDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSFTHTAVDNILLKLAKFKVGFLRLGRAQKVHPDIRKFTEEEICR-SKSIKSVTDLEELYNSQPVVATACMGINHPIFVQKQFDFCIVDEASQISQPICLGPLFCSKRFVLVGDHQQLPPLVQNSEARDLGMSESLFKRLEQNQNAVVQLTVQYRMNSKIMSLSNKLVYEGKLECGSEKVSNATANLPNLKMLKLEFADASKTWLKEVLEP--DKPVCFLNT---------EKAG-CRPSD----------------IGIISPYRHQLKVITDLMARLKENRVEVNTIDKYQGRDKSIIIVSFVRNSNDENLGA-------LLKDWRRLNVAITRAKHKLIMVGCVPSLRRYPPLEKLLCHLQSEAMIFNLP 979          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|408407704|sp|E1BMP7.3|DNA2_BOVIN (RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; AltName: Full=DNA replication ATP-dependent helicase-like homolog; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2)

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 344/986 (34.89%), Postives = 543/986 (55.07%), Query Frame = 0
Query:  109 CRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNE----LVTHLRPSTPDGSAWPALPEPINLKRACAQCPHLMTCA-----ISQKLESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVT---HLHTFGRHSNSTETLMGVFQTGETVVLSSD--TELALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTF----AKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVA-LNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTL-NDENRHLNVA---------WLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTL----IRSLGSVHSIGVVAPYRAQV----NLLRQKLDPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVP 1057
            C L   W    V  GD++H+  E     N +++++  G L++ PD L+SGTS+ +S+ C+R+AVL+E F+  +  ++ M IGT++HE+ Q  ++         E   Q +     +++ +  L ++  +++QEVE +LP    +   ++    +   P              +     V    DIEE+IWSPR G+KGK+D+TV VK+H   +      IMPLELKTG+ S S EHR Q+++Y+++  ERR DPE+GLLLYL+   +  V A   + R L++LRN+    L   +  ST + +    LP+ I  ++ C  C  +  CA     + Q++E +  + P +M   + +   HL  I L++F  W  M  LE+Q    K   + +W     + E   S +  L  +     V    +LH F R + +    +     G+ ++LS +  T  AL++G +  ++   ++  LD+ L   P +    ++ LD+ E    + + L NL+KLM +   +Q+LR  +I  +   F    +  LP +       IL+ LN  Q++A+ K+L++ D+  + GMPGTGKTT I  LVR++ A G ++LLTSYTHSAVDNILLKL   +  FLRLG++ ++HPD++ F+ E   +   +  SL  +++ + +  IVATTC+G+NHP   ++ FD+CIVDEASQ      LG LF   +FVLVGD  QLPP+V +  AR LGM  SLF  LE+  N V  L +QYRMN+ IM+ +N LTY G+L+CGS +++   + L N ++  L +          WL  A  P   + V F++T  +P  +  ++ G++N  EA L V L    I++      IG++APYR Q+    +LL Q     V+VNTVD++QG+DK +++    R+    E G  G    ++L D RRLNVAITRAK K I++G  P+L +YPP+ +LL +L     +  +P
Sbjct:   81 CILRNDWCSVPVEPGDIIHL--EGDCISNTWIIDEDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSDPATRQMLIGTVLHEVFQKAVSDSFAPEKLQELASQTIQEIRHLKE-MYRLKLNQDEIKQEVEEYLPSFSKWAGDFMHKHTSTDFPQMQLSLPSDGSNSNSTCNIEVTNSLDIEESIWSPRFGLKGKIDVTVGVKIHRGCKTKYK--IMPLELKTGKESNSIEHRSQLVLYTLLSQERRADPEAGLLLYLKTGQMYPVPAKHLDKRELLRLRNQMAFSLFHRINKSTGEKTELAPLPQIIEEQQTCKYCSQMGNCALYSRAVEQQMEDS--SVPTSMWPKIKEETQHLKPIHLEYFSLWCLMLTLESQSKDNKRNYQHIWLMPASEMEESGSCIGSLIRIEHVKTVCDGQYLHNFQRKNGAIP--ITNLMAGDRIILSGEERTLFALSRGYVKEINSTTVTCSLDRNLSGLPES---TLFRLDQEEKNCDIDTPLGNLSKLMENTRASQKLRDLIIDFREPQFISYLSSVLPHEAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPDIQKFTEEEICR-SKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKTFDFCIVDEASQISQPVCLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKNAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLPNFKDVKLELEFYADYSENPWLIAAFEPN--NPVCFLNTHKVPAPEQVEKGGVSNIMEAKLVVFLTSVFIKAGCKPSDIGIIAPYRQQLKVISDLLAQSSVGMVEVNTVDRYQGRDKSIVVVSFVRS---NEDGTLG----ELLKDWRRLNVAITRAKHKLILLGCVPSLSRYPPLRKLLNHLNSEKLIIDLP 1044          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|119370373|sp|P51530.3|DNA2_HUMAN (RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; Short=hDNA2; AltName: Full=DNA replication ATP-dependent helicase-like homolog; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2)

HSP 1 Score: 551.206 bits (1419), Expect = 6.360e-178
Identity = 342/998 (34.27%), Postives = 544/998 (54.51%), Query Frame = 0
Query:  109 CRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPP------PAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHL-----RPSTPDGSAWPALPEPINLKRACAQCPHLMTCAI-SQKLESAVPAE--PHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALA------HLKLVAQSDRVTHLHTF-GRHSNSTETLMGVFQTGETVVLSSDTE--LALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTF----AKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEE-PSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHL--------------NVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTL----IRSLGSVHSIGVVAPYRAQVNLLRQKLDPN---VDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVP 1057
            C L   W    V  GD++H+  E     + ++++   G L++ PD L+SGTS+ +S+ C+R+AVL+E F+  +  ++ M IGT++HE+ Q  + +        E  FQ +     +++ +  L++S  +++QEVE +LP    +   ++    +   P      P+ +    +      V P       DIEE+IWSPR G+KGK+D+TV VK+H   +      IMPLELKTG+ S S EHR QV++Y+++  ERR DPE+GLLLYL+   +  V A   + R L++LRN++   L     + +T   +   +LP+ I  ++ C  C  +  CA+ S+ +E  +     P  M   + +   HL +  L++F  W  M  LE+Q    K   +++W     + E   S +       H+K+V       +LH F  +H     T +     G+ V++S +     AL++G +  ++   ++ +LD+ L   P +    ++ LD+ E    + + L NL+KLM +   +++LR  +I  +   F    +  LP D       IL+ LN  Q++A+ K+L++ D+  + GMPGTGKTT I  LVR++ A G ++LLTSYTHSAVDNILLKL   +  FLRLG++ ++HP ++ F+ E +     +  SL  +++ + +  IVATTC+G+NHP   ++ FD+CIVDEASQ      LG LF   +FVLVGD  QLPP+V +  AR LGM  SLF  LE+  S  V L +QYRMN+ IM+ +N LTY G+L+CGS +++   + L    RH               +  WL     P   + V F++T  +P  +  ++ G++N  EA L V L    +++  S   IG++APYR Q+ ++   L  +   V+VNTVD++QG+DK ++L    R+      G       ++L D RRLNVAITRAK K I++G  P+L  YPP+ +LL +L     +  +P
Sbjct:   80 CILRNDWCSVPVEPGDIIHL--EGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSDPATRQMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKE-MYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKP------MDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYK--IMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQ---YLHNFQCKHGAIPVTNL---MAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPES---TLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFT-EQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINL----RHFKDVKLELEFYADYSDNPWLMGVFEPN--NPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVG-------ELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLP 1043          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|408407615|sp|F6QXW0.1|DNA2_XENTR (RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; AltName: Full=DNA replication ATP-dependent helicase-like homolog; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2)

HSP 1 Score: 439.884 bits (1130), Expect = 6.927e-136
Identity = 334/1039 (32.15%), Postives = 518/1039 (49.86%), Query Frame = 0
Query:   79 GRHEVLAVERLLSE-----LQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPH-----IQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSL-IMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNEL---VTHLRPSTPDGS---AWPALPEPINLKRACAQCPHLMTCA-----ISQKLESA-VPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVT---HLHTFGRHSNST--ETLMGVFQTGETVVLSS-DTELALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKG----LPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHES--------NFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLN-HPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVA-LNIQYRMNATIMACANHLTYVGQLQCGSPEIS--------LKTLTLNDENRHLNVA-WLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALLAVTLIRSLGSV----HSIGVVAPYRAQVNLLRQKLD----PNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVP 1057
             R+ VL V+ + ++     L +    EG   E+  C L   W+   +  GD++H L    +  N + ++   G L++ PD L+SGTS+   + CLR++VL+E+FK  +  S+ M IGT++H++ Q        T S ++E     +      + +  L ++   V  EV+ +LP      I F T      Q     P A  P +            +V E  DIEENIWSPR G+KGK+D+T RVK+H +    +S L IMPLELKTG+ S S EHR QV++Y+++  ERR DPE+GLLLYL+  ++  V     + R L+++RNEL   +T++   + +GS      +LP  I  ++AC  C  +  CA     + Q++E+  +PAE   M  +V K   HL++  L++F+ W  MC LE      K   K++W  +  +RE     + +L        ++   HLH+F R S +     LM    +G+ VV+S  D  LAL+ G I  +    I+ +LD++L + P    D ++ LD  E  G + S+L NL++LM + P + +LR  +I      F +     LP D   +   IL+ LN  Q++A+ ++L++ D+  + GMPGTGKTT I  LV        T+ L + T   VD+       H S        N  +  R  R+       SA+ +S+   A  S EN K + +     +  C+ +N H    + N+    +       LL  L   + C  F L+        V   S  RELGM  SLF  LE     V  L +QYRMN+ IMA +N L Y G+L+C S  +S        +KTL L  E R    + W+   L P   + V F++T+ IP  +  ++ G++N  EA L   L +           IG++APYR Q+ ++    +      V+VNTVD++QG+DK VI+    R+    + G       D+L D RRLNVA+TRAK K IM+G  PTL ++  + +L+ +L     +  +P
Sbjct:   52 NRYCVLNVKEVYAQGEEKHLTITASQEGDDLEL--CILKDDWVALHIKPGDIIH-LEGNCAFDNTWTISRDTGYLILYPDLLISGTSIANGIRCLRRSVLSEKFKVCDKGSRQMLIGTMLHDIFQRATTRGF-TDSVLQELAHHTVHGPKYLKEMYQLKLNQTDVMGEVQEYLPSFAKWAIDFMTHPLNQHQINVTRPTAGDPTEAT----------KVSEFLDIEENIWSPRFGLKGKIDVTARVKIHQK---SKSHLKIMPLELKTGKESNSIEHRSQVVLYTLLSQERREDPEAGLLLYLKTGNMYSVPGNRLDRRELLKIRNELSYYLTNVVHKSDNGSKEITLASLPALIADRQACKFCSQMRNCALYSRSVEQQIENCYIPAE---MIPVVQKETEHLNKDHLQYFRLWYLMCTLEGNSKDSKMGRKNIWMMSSSEREEDGQCIGNLIRTGPVQTISDGQHLHSFQRKSGTVPATNLM----SGDRVVVSGEDKFLALSSGYIKEVKHNNITCILDRSLGKLPE---DLLFRLDHEEGGGGLESHLGNLSRLMENSPVSDKLRKLIIDFSKPNFVQHLSSVLPSDAKDIVANILKGLNKPQKQAMKRVLLSKDYTLIVGMPGTGKTTTICTLV-------STLHLKTCTSCLVDDHREAAGTHRSHRHSKGTVNLGKQKRQHRVTSTTSSTSAKCRSKTEPAV-SAENKKLQKLISG--SHVCIMVNGHKTFSQNNY----IIFFDNILLLKKLPLHYMC-AFALIHHQCFKGCVKSVSLVRELGMSESLFKRLERNQEAVVQLTVQYRMNSQIMALSNKLVYEGRLECASDRVSNAVVKLPHIKTLLLELEFRESQESMWIKDVLEP--SNPVCFLNTEKIPALETEEKGGISNWIEAKLVFCLTKLFLKAGCRPSDIGIIAPYRQQLKVISNYFNSLSASAVEVNTVDKYQGRDKSVIIVSFVRSNIDGKLG-------DLLKDWRRLNVALTRAKHKLIMLGCVPTLSRFLCLEQLICHLKSKNHIYDLP 1039          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|408360057|sp|Q9URU2.2|DNA2_SCHPO (RecName: Full=DNA replication ATP-dependent helicase/nuclease dna2; Includes: RecName: Full=DNA replication nuclease dna2; Includes: RecName: Full=DNA replication ATP-dependent helicase dna2)

HSP 1 Score: 404.06 bits (1037), Expect = 5.586e-120
Identity = 319/1008 (31.65%), Postives = 495/1008 (49.11%), Query Frame = 0
Query:  108 QCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGP-SKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRP-DPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTH-LRPSTPDGSAWPALPEPINLKRACAQCPHLMTCAISQKLESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQS-------DRVTHLHTFGRHSNST--ETLMGVFQTGETVVLSSD-TELALAQGVIVSLDEGQIST------------VLDKTLKQDPTTQGD-------------KIYHLDRYEYQGSMASNLVNL-AKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEE--PSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHL---------NVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLTNPKEALL---AVTLIRSLG-SVHSIGVVAPYRAQVNLLRQKLDP--NVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPED 1059
            Q  L G W  T +  GD + V A      N  +V++  GL+++ P  L+S T+V +S  CLR+AV+++R  G+ GP +K M  G ++H+  Q  L   +     V+   +  + ++ I     + D+SL ++R+E++  LP ++   E+Y++ +       + H                +  + DIEE+IWSPR G+KG +D TV V L  +     S+L +PLELKTGR   +  H  Q ++Y++++++R   +    LL YL NS+++ + A   ++RGL+  RN L  H  R S         LPE I+ ++ C  C  +  C   QK+     A  + +++   + +  + + DL+F++ W ++  L  +E     K  D+      + EA    L  L +  +        DRV H      + N      L   F  GE V +S +    +LA+G IV + +  I              + +   K++    G+               Y +D+ E+   +AS    L + ++ D P    +R  +I  KP  F        A +    L+ LN  Q  A+ K   A  +  + GMPGTGKTT I +L+R ++A  K ILLTS+TH AVDNIL+KL+  +S  +RLG   +IHP ++ F       EG   D L ++K  +    IVA + LG+ H    KR FDYCI+DEASQ  L   LG L   EKFVLVGD  QLPP+V++SR  + G+  SLF  L E  P     L +QYRMN  I + ++ L Y G L CGS  IS K L L     HL         ++ W+ + ++P    SV+F +T +I   +    + L N  EA L   AV+     G    SIG+++ Y++QV LL + L     +++NTVD++QG+DKD+IL    R+      G       ++L D  RLNVA++RAK K IM G   TL     +  LL  L +   +  + E+
Sbjct:  392 QLFLRGDWTETSIFVGDSIRVEATFD-KDNTAIVDNDKGLIIIHPKILMSATAVASSFPCLRKAVISDRV-GIYGPPTKAMVTGNILHDFFQHALYRGIDALENVDINLETSI-KTYISDIYFA-DLSLDEIREELDARLPLLKSIVERYLISKKNDNNNESIH----------------ISRLLDIEESIWSPRFGLKGNIDATVEVVLTEKPE-SSSTLTLPLELKTGRYVDNISHFAQSLLYTLLISDRYGINTNQALLCYLENSTIKNLVASNSQLRGLIMTRNSLAQHNFRRS---------LPEMISNRKICDHCSLVSECLFFQKMSDKGVANSNGLTESWNEWMREVKDEDLEFYKKWEKL--LNQEERLLLLKRGDVLTFDTEELEAYGKTLYPLYITKEDIVCLEIDDRVFHYKFAFLNDNGYPRNFLHSGFSVGERVFISDEHGHWSLAKGHIVHIQDSCIEVRTRHRLHIPWLKMPNFDFKKNQVFFGNYEDSKLSFIGSNHTRYRIDKDEFSSGIASIRGTLMSSVLPDAPLI--IRDMIIRLKPPKFCNS-----ALIDPEFLKCLNEDQITALKKCHAAEHYSLILGMPGTGKTTTISSLIRSLLAKKKKILLTSFTHLAVDNILIKLKGCDSTIVRLGSPHKIHPLVKEFCL----TEGTTFDDLASLKHFYEDPQIVACSSLGVYHSIFNKRKFDYCIIDEASQIPLPICLGPLQLAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSEKHPEAVTTLRLQYRMNEDINSLSSELIYGGNLVCGSKTISQKKLIL--PKAHLSDGLPDSSSSLHWVNKLINP--SHSVIFFNTDDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQSSIGIISIYKSQVELLSKNLKSFTEIEINTVDRYQGRDKDIILISFVRSNSKNLVG-------ELLRDWHRLNVALSRAKVKCIMFGSLSTLSSSNIVSHLLKLLEKNKWIFTLNEN 1345          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|731738|sp|P38859.1|DNA2_YEAST (RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2)

HSP 1 Score: 364.385 bits (934), Expect = 3.427e-105
Identity = 302/1052 (28.71%), Postives = 506/1052 (48.10%), Query Frame = 0
Query:  115 WLHTRVSAGDLVHVLAERQSAGNEYLVNDRG--------GLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEG-PSKTMFIGTLVHELLQDC----LAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEV-EPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYL-RNSSLQEVKAGIHEMRGLVQLRNELVTHLRPSTPD--GSAWPALPEPINLK-RACAQCPHLMTCAISQKL-ESAVPAEP-------HAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVTHLHTFG---------RHSNSTETLMGVFQTGETVVLSSDTE--LALAQGVIVSLDEGQIS-----------------------TVLDKTLKQDP--TTQGDKIYHLDRYEYQGSMA---SNLVNL---------------AKLMADQPRA----QQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHP--AVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFS--CLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTL---NDENRHLNVA-----WLARALSPKLEDSVLFVDTQNIPTEDVSDQS---GLTNPKEALLAVTLIRS--LGSV--HSIGVVAPYRAQVNLLRQKLDPNV----DVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPED 1059
            W++     GD++H++  +       L +D+          LLV+ PD L S TSV +S+ CLR+++L  +F+   G PS  M +G +VHELLQD     L+H+  +   + ++   +L   +   +I+  +  +  V++ V +    +I +F  K+V    +      +    G     P      +  V DIEENIWSP  G+KG +D TV   +    +      I+PLE+KTG+ S S  +  Q ++Y++++ +R   P    LLY  R+ ++ +  + +H ++ ++  RN +  + +    +  G A      P  L+  +C  C    +C +  KL E   P E          +++ + + LA+  E    FF  ++ +   E  E+S     K+L+      RE++      L  +  S+ V H  T G         R+ N++++++         V+ SD E    L QG +  ++  +I                        +V++  L+Q     TQ    Y +D+ + Q S++    NL++L               +KL     R+    + LR+ L+  +   F       +         +LN  Q+ AI K++ A D+  + GMPGTGKTT+I  +++++V+ GK +LLTSYTHSAVDNIL+KLR    + +RLG   ++HPD + +   + S +     S  +   +  +  +VATTCLG+N     + +++FDY I+DEASQ  +  ALG L +  +F++VGD  QLPP+V++  AR  G++ SLF   C + P +   L +QYRM   I+  +N L Y  +L+CG+ E+  ++L L      +R+ N +     WL   L P  +  V+F++  N P  D+ +QS    +TN  EA L +  +    L  V    IGV+  YRAQ+ LL++  + NV    ++ T DQFQG+DK  I+    R       G        +L + RR+NVA+TRAK K I++G   T+   P I   +  L E   V  + +D
Sbjct:  459 WVYLEFEVGDVIHIIEGKNIENKRLLSDDKNPKTQLANDNLLVLNPDVLFSATSVGSSVGCLRRSILQMQFQDPRGEPSLVMTLGNIVHELLQDSIKYKLSHNKISMEIIIQKLDSLLETYSF--SIIICNEEIQYVKELVMKEHAENILYFVNKFV----SKSNYGCYTSISGTRRTQPI----SISNVIDIEENIWSPIYGLKGFLDATVEANVENNKKH-----IVPLEVKTGK-SRSVSYEVQGLIYTLLLNDRYEIPIEFFLLYFTRDKNMTKFPSVLHSIKHILMSRNRMSMNFKHQLQEVFGQAQSRFELPPLLRDSSCDSCFIKESCMVLNKLLEDGTPEESGLVEGEFEILTNHLSQNLANYKE----FFTKYNDLITKE--ESSITCVNKELFLLDGSTRESRSGRC--LSGLVVSEVVEHEKTEGAYIYCFSRRRNDNNSQSMLSSQIAANDFVIISDEEGHFCLCQGRVQFINPAKIGISVKRKLLNNRLLDKEKGVTTIQSVVESELEQSSLIATQNLVTYRIDKNDIQQSLSLARFNLLSLFLPAVSPGVDIVDERSKLCRKTKRSDGGNEILRSLLVDNRAPKFRDANDDPVIPYKLSKDTTLNLNQKEAIDKVMRAEDYALILGMPGTGKTTVIAEIIKILVSEGKRVLLTSYTHSAVDNILIKLRNTNISIMRLGMKHKVHPDTQKYVPNYASVK-----SYNDYLSKINSTSVVATTCLGINDILFTLNEKDFDYVILDEASQISMPVALGPLRYGNRFIMVGDHYQLPPLVKNDAARLGGLEESLFKTFCEKHPESVAELTLQYRMCGDIVTLSNFLIYDNKLKCGNNEVFAQSLELPMPEALSRYRNESANSKQWLEDILEPTRK--VVFLNYDNCP--DIIEQSEKDNITNHGEAELTLQCVEGMLLSGVPCEDIGVMTLYRAQLRLLKKIFNKNVYDGLEILTADQFQGRDKKCIIISMVRRNSQLNGGA-------LLKELRRVNVAMTRAKSKLIIIGSKSTIGSVPEIKSFVNLLEERNWVYTMCKD 1470          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Match: gi|2498040|sp|Q60560.1|SMBP2_MESAU (RecName: Full=DNA-binding protein SMUBP-2; AltName: Full=ATP-dependent helicase IGHMBP2; AltName: Full=Immunoglobulin mu-binding protein 2; AltName: Full=Insulin II gene enhancer-binding protein; AltName: Full=RIPE3B-binding complex 3B2 p110 subunit; Short=RIP-1)

HSP 1 Score: 135.961 bits (341), Expect = 3.333e-31
Identity = 132/472 (27.97%), Postives = 201/472 (42.58%), Query Frame = 0
Query:  647 SLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSR---------------------IHPDLR-----VFSAEHQSQEGMASDSLEN--------MKDR--------FMTCPIVATTCLGLNHPA----VQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVA---LNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVAWLARALSPKLEDSVLFVDTQ--NIPTEDVSDQSGLTNPKEALLAVTLIRSL--GSVHS--IGVVAPYRAQVNLLRQKLD---PNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPEDL 1060
            +L+P Q+ A+   L   +   + G PGTGKTT +V ++   V  G  IL  + ++ AVDN++ +L   +   LRLG  +R                     I  D+R     VF    ++Q+     +  N        +K+R             +V  T  G +       + + +FD  +VDE +QA   S    L    K +L GD  QLPP   S +A   G+  SL   L E     A   L +QYRM+  I   A+   Y GQL    P ++           HL       A + +    +L +DT    +   D  D     NP E  L    I++L    VH+  I V+APY  QV+LLRQ L    P +++ +VD FQG++K+ ++    R+    E G         L + RR+NVA+TRA+    ++    T+  +  +  L+ Y  E G V    E L
Sbjct:  190 ALDPSQKEAVSFALAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKILCCAPSNVAVDNLVERLALCKKRILRLGHPARLLESAQQHSLDAVLARSDNAQIVADIRKDIDQVFGKNKKTQDKREKSNFRNEIKLLRKELKEREEAAIVQSLTAADVVLATNTGASSDGPLKLLPENHFDVVVVDECAQALEASCWIPLLKAPKCILAGDHRQLPPTTISHKAALAGLSRSLMERLVEKHGAGAVRMLTVQYRMHQAITRWASEAMYHGQL-TAHPSVA----------GHLLKDLPGVADTEETSVPLLLIDTAGCGLLELDEEDSQSKGNPGEVRLVTLHIQALVDAGVHAGDIAVIAPYNLQVDLLRQSLSNKHPELEIKSVDGFQGREKEAVILTFVRSNRKGEVG--------FLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVDYFTEHGEVRTAFEYL 642          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|919004379|ref|XP_013379222.1| (DNA replication ATP-dependent helicase/nuclease DNA2 [Lingula anatina])

HSP 1 Score: 714.916 bits (1844), Expect = 0.000e+0
Identity = 427/1026 (41.62%), Postives = 619/1026 (60.33%), Query Frame = 0
Query:   69 VDPPALAAAYGRHEVLAVERLLSELQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHLRPSTP-----DGSAW--PALPEPINLKRACAQCPHLMTCAISQK-LESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRV------THLHTFGRH--SNSTETLMGVFQTGETVVLSSDT--ELALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKD--RFMTCP-IVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLND------ENRHLNVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLT-NPKEA----LLAVTLIRSLGSVHSIGVVAPYRAQVNLLRQKLDPN--VDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLG--ETGTVTLVPE 1058
            +D  A A  +GRH VLAV    +E+ L++    S ++  +C L+G W  T V  GD+V+VL +   +G  + ++D  GLLV+ PD L+SGTSVV +++C+R+ +LNE+ +G +  +  M  G+++H L Q  +     ++ +VE   + +L +      +   D + A VR E++ ++P +  +TEKY+     PPP  +F    GA P    +    V +V DIEENIWSPR G+KGK+DLTV+VK++G+ +  +   +MPLELKTG+PS S EH+GQV +YS+M ++RR DP  GLLLYL++ S++ + A   + RGL+QLRNELV +L  +T       G+ +  P LP PIN  R+C++CP L+ CA+ Q+ ++     + HAM+ L+P TLAHL +  L++F  W  +  LEA+E+ +   LKD+WC++  QRE + + L+ + L+ + D V      + +HTF +     S +  +  F  G+++V+S  T   +AL    +V + + +I+ +LD+ L Q+     D +Y LD+ +   SMASN  NL+KL++D P + +LR  +I  +   F   L K      K I +SLN  Q+ AI K+LM  D+V +KG PGTGKT+ IVALVR++  LG +ILLTSYTHSAVDNILLKL+  +  FLRLGR SRIHP++  +S      EG  + +++ + D   F T   IVATTCLG NH    KR FD CI+DEASQ    +  G L    KFVLVGDP QLPPVVQS+ ARELGMD SLF  L+       LN+QYRMN++IM  +N L Y G L+CGS +++   L L++      E   +  AWL  ALSP+    VLF+DT NI   +  D  GL  N  EA     LA   +R   S   +G++APYR QV +L  +L  +  V+VNTVDQ+QG+DK VI+    R+    ++  KG    +IL D RRLNVA+TRAK K + +G   TL KY P+ +L+  L   E   +T VP+
Sbjct:  349 IDSRAPAVQFGRHLVLAVHHERNEVILDVE-SASGNQRRKCVLSGFWTDTLVQPGDIVNVLGDFDDSGVCH-ISDNQGLLVINPDVLISGTSVVGTVYCMRKTLLNEKLRGCDTGNMAMLHGSIIHALFQAVVQQRAFSKDKVEAIVKEILQQKKFLIEMYGQDATEAVVRAEIDKYIPPMLAWTEKYM-----PPPVHSF----GARPSTSDL---HVTKVMDIEENIWSPRYGVKGKIDLTVQVKINGKQKCEK---VMPLELKTGKPSFSIEHQGQVTLYSLMSSDRREDPGGGLLLYLKDGSMKTITADYAKKRGLLQLRNELVHYLSLNTEKVESESGTTYHLPKLPRPINNPRSCSKCPQLLNCAVYQRSIDHHDLPDDHAMTSLIPATLAHLHQSHLEYFSHWCLLQELEAKESYKS--LKDIWCKSAEQREKEGNCLSDMVLMDRHDAVLALDNGSFIHTFHKQPSKQSPKISLAGFSKGDSLVVSGQTSGHIALCTASVVQVTQTEITVILDRNL-QNTNLNSDAVYRLDKNDSFNSMASNYTNLSKLLSDNPHSLRLRELIIDARKPEFELTLAKGAIEKVKHIFKSLNKPQKTAILKILMCKDYVLMKGYPGTGKTSTIVALVRILHQLGLSILLTSYTHSAVDNILLKLKKLDLEFLRLGRESRIHPEILPYS------EGTLTKNIKTVGDLAEFYTAKQIVATTCLGTNHVLFTKRRFDICIIDEASQVLQPTCFGPLSCAAKFVLVGDPKQLPPVVQSTEARELGMDESLFMRLDNTGATYELNLQYRMNSSIMRLSNELVYEGALKCGSQDVAEARLQLSNMEDVRAELSGMMPAWLECALSPQ---PVLFLDTDNISATESYDAQGLVKNDLEAEIVCQLAKCFLRGGLSPQELGIIAPYRNQVKVLHTRLGGSGEVEVNTVDQYQGRDKSVIILSFVRSNSKDDSSSKGRGGTEILCDWRRLNVAVTRAKHKLLFVGSVSTLKKYQPLQKLIQILNPEEICQITSVPD 1345          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|1238875841|ref|XP_022251495.1| (DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X2 [Limulus polyphemus] >gi|1238875843|ref|XP_022251496.1| DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X2 [Limulus polyphemus])

HSP 1 Score: 695.656 bits (1794), Expect = 0.000e+0
Identity = 414/1014 (40.83%), Postives = 613/1014 (60.45%), Query Frame = 0
Query:   80 RHEVLAVERLLSE-LQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNS-SLQEVKAGIHEMRGLVQLRNELVTHLRPSTPDGSAWPA-----LPEPINLKRACAQCPHLMTCAISQK-LESAVPA-EPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVA------QSDRVTHLHTFGRHSN-STETLMGV-FQTGETVVLSSD---TELALAQGVIVSLDEGQISTVLDKTLKQDPTTQG--DKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDEN--RHLNV--AWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGL-TNPKEALLAVTLIRSLGSV----HSIGVVAPYRAQVNLLRQKLDPN----VDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPE 1058
            R+ V +V++   + + L L PE  SS +  C L G W  T VS GD VHV+A         ++ND  GLLVV PDHLVS TSVV+SLFC+R+AVL E+F+G E  + +M  G+L+HEL Q+ + H + ++ +++ R +V+L + +    +  L ++  ++  E+  +LPHI  + + Y+L  + P    A +  +            ++E V DIE+NIW P+ G+KGK+DLTV V +H R +  + ++  PLELKTG+P+ S EH+GQV +Y+MMM++R  DPE GLLLYL+    ++        +RGL+QLRNEL +H      D     A     LPEPI+ KRAC +CPHL++C++ Q+ +E   P+ E H MS LVP+TL HL    L +F++W  +  LE   A+ +      W +    RE +   L+ + L +      Q D    + TF ++S+ S + L  +     + V++S D    E+A+A G ++S+    +  V DK L      QG    ++ +D       +A N VNLA+LM+  P+A+++R+++I RK   +   L K +    + I++ LN  QQRA+ K LM  D++  +GMPGTGKT  IV+LVR++V  G ++LLTSYTHSAVDNILLKL  H  +F+RLG L RIHP ++ F +E  +++    +S+E + + +++ P+VATTCLG+NH   +KR FD+CI+DEASQ   +++LG L HC +FVLVGDP QLPPVVQS +AR+LGM  SLFS L  P N + LNIQYRMN+ IM+ +N LTY G L+CGS E +  TLTL + +  RH     +W   AL+ +L+ SV+ ++T  +P ++  +  GL +NP E  L   L   L        +IGV+ PYR QV+LLR+ L  +    ++VNTVDQ+QG+DK+ +++   R+     +G       +IL DARRLNVAITRAK K I++G   TL+ Y P  +LL+ L E   + L PE
Sbjct:  464 RYRVASVQKSADQGVLLRLNPEDDSSSLKTCSLQGFWTDTLVSEGDNVHVIA--SFVNGHCVINDEYGLLVVNPDHLVSSTSVVSSLFCMRKAVLMEKFRGWEKGNLSMLQGSLIHELFQEVVQHKIVSQDEMKRRLKVLLNQQSSLHEMYGLGITETELETEMMSYLPHIHEWIQHYML--SGPSQLKADNCNENTDLI-------KIEAVQDIEDNIWCPKFGIKGKIDLTVDVTIHSRGKSQKKTV--PLELKTGKPTFSMEHQGQVTLYTMMMSDRSTDPEEGLLLYLQGGPQMKRFSTEHRNVRGLIQLRNEL-SHYTGKVLDMGQNMAPRSAHLPEPISNKRACTKCPHLLSCSLYQRAIEDYTPSSENHPMSILVPETLNHLSSDHLAYFKNWILLLNLELS-ATHQKYGTSFWNEDSLLREKKGICLSGMTLRSSVKHSKQLDSGQWVMTFQKNSSASFDNLKNIGLNPCDFVLISKDGICQEVAIAMGTVLSVLNNSVEVVTDKDL---TMRQGWEHMVFRIDLNVSFSVIAVNFVNLARLMSPDPQAEKIRSFVIDRKQPKYLNRLDKQVVLNGREIMKCLNKPQQRAVLKTLMCKDYIMWRGMPGTGKTLAIVSLVRILVKFGYSVLLTSYTHSAVDNILLKLLNHNVDFIRLGHLGRIHPQIQPFCSEKLTKD---VNSVEELTNFYLSKPVVATTCLGINHVLFRKRKFDFCIIDEASQILQVASLGPLLHCHRFVLVGDPQQLPPVVQSKQARDLGMAESLFSRLSTPDNTIDLNIQYRMNSEIMSLSNLLTYNGALECGSEETANATLTLFNTSFVRHFPSLDSWPMIALAAELKYSVVVLNTDLVPAKEACNLQGLVSNPVEVELVTQLALLLLKGGLEQKNIGVITPYRRQVHLLREALGAHNVCELEVNTVDQYQGRDKEAVIFSCVRSNQENSSG-------EILHDARRLNVAITRAKHKLIIIGSKMTLLFYEPFRQLLSALKECQLLDLPPE 1449          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|1238875837|ref|XP_022251493.1| (DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X1 [Limulus polyphemus] >gi|1238875839|ref|XP_022251494.1| DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X1 [Limulus polyphemus])

HSP 1 Score: 695.656 bits (1794), Expect = 0.000e+0
Identity = 414/1014 (40.83%), Postives = 613/1014 (60.45%), Query Frame = 0
Query:   80 RHEVLAVERLLSE-LQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNS-SLQEVKAGIHEMRGLVQLRNELVTHLRPSTPDGSAWPA-----LPEPINLKRACAQCPHLMTCAISQK-LESAVPA-EPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVA------QSDRVTHLHTFGRHSN-STETLMGV-FQTGETVVLSSD---TELALAQGVIVSLDEGQISTVLDKTLKQDPTTQG--DKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDEN--RHLNV--AWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGL-TNPKEALLAVTLIRSLGSV----HSIGVVAPYRAQVNLLRQKLDPN----VDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPE 1058
            R+ V +V++   + + L L PE  SS +  C L G W  T VS GD VHV+A         ++ND  GLLVV PDHLVS TSVV+SLFC+R+AVL E+F+G E  + +M  G+L+HEL Q+ + H + ++ +++ R +V+L + +    +  L ++  ++  E+  +LPHI  + + Y+L  + P    A +  +            ++E V DIE+NIW P+ G+KGK+DLTV V +H R +  + ++  PLELKTG+P+ S EH+GQV +Y+MMM++R  DPE GLLLYL+    ++        +RGL+QLRNEL +H      D     A     LPEPI+ KRAC +CPHL++C++ Q+ +E   P+ E H MS LVP+TL HL    L +F++W  +  LE   A+ +      W +    RE +   L+ + L +      Q D    + TF ++S+ S + L  +     + V++S D    E+A+A G ++S+    +  V DK L      QG    ++ +D       +A N VNLA+LM+  P+A+++R+++I RK   +   L K +    + I++ LN  QQRA+ K LM  D++  +GMPGTGKT  IV+LVR++V  G ++LLTSYTHSAVDNILLKL  H  +F+RLG L RIHP ++ F +E  +++    +S+E + + +++ P+VATTCLG+NH   +KR FD+CI+DEASQ   +++LG L HC +FVLVGDP QLPPVVQS +AR+LGM  SLFS L  P N + LNIQYRMN+ IM+ +N LTY G L+CGS E +  TLTL + +  RH     +W   AL+ +L+ SV+ ++T  +P ++  +  GL +NP E  L   L   L        +IGV+ PYR QV+LLR+ L  +    ++VNTVDQ+QG+DK+ +++   R+     +G       +IL DARRLNVAITRAK K I++G   TL+ Y P  +LL+ L E   + L PE
Sbjct:  465 RYRVASVQKSADQGVLLRLNPEDDSSSLKTCSLQGFWTDTLVSEGDNVHVIA--SFVNGHCVINDEYGLLVVNPDHLVSSTSVVSSLFCMRKAVLMEKFRGWEKGNLSMLQGSLIHELFQEVVQHKIVSQDEMKRRLKVLLNQQSSLHEMYGLGITETELETEMMSYLPHIHEWIQHYML--SGPSQLKADNCNENTDLI-------KIEAVQDIEDNIWCPKFGIKGKIDLTVDVTIHSRGKSQKKTV--PLELKTGKPTFSMEHQGQVTLYTMMMSDRSTDPEEGLLLYLQGGPQMKRFSTEHRNVRGLIQLRNEL-SHYTGKVLDMGQNMAPRSAHLPEPISNKRACTKCPHLLSCSLYQRAIEDYTPSSENHPMSILVPETLNHLSSDHLAYFKNWILLLNLELS-ATHQKYGTSFWNEDSLLREKKGICLSGMTLRSSVKHSKQLDSGQWVMTFQKNSSASFDNLKNIGLNPCDFVLISKDGICQEVAIAMGTVLSVLNNSVEVVTDKDL---TMRQGWEHMVFRIDLNVSFSVIAVNFVNLARLMSPDPQAEKIRSFVIDRKQPKYLNRLDKQVVLNGREIMKCLNKPQQRAVLKTLMCKDYIMWRGMPGTGKTLAIVSLVRILVKFGYSVLLTSYTHSAVDNILLKLLNHNVDFIRLGHLGRIHPQIQPFCSEKLTKD---VNSVEELTNFYLSKPVVATTCLGINHVLFRKRKFDFCIIDEASQILQVASLGPLLHCHRFVLVGDPQQLPPVVQSKQARDLGMAESLFSRLSTPDNTIDLNIQYRMNSEIMSLSNLLTYNGALECGSEETANATLTLFNTSFVRHFPSLDSWPMIALAAELKYSVVVLNTDLVPAKEACNLQGLVSNPVEVELVTQLALLLLKGGLEQKNIGVITPYRRQVHLLREALGAHNVCELEVNTVDQYQGRDKEAVIFSCVRSNQENSSG-------EILHDARRLNVAITRAKHKLIIIGSKMTLLFYEPFRQLLSALKECQLLDLPPE 1450          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|1238875845|ref|XP_022251497.1| (DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X3 [Limulus polyphemus])

HSP 1 Score: 695.271 bits (1793), Expect = 0.000e+0
Identity = 414/1014 (40.83%), Postives = 613/1014 (60.45%), Query Frame = 0
Query:   80 RHEVLAVERLLSE-LQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNS-SLQEVKAGIHEMRGLVQLRNELVTHLRPSTPDGSAWPA-----LPEPINLKRACAQCPHLMTCAISQK-LESAVPA-EPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVA------QSDRVTHLHTFGRHSN-STETLMGV-FQTGETVVLSSD---TELALAQGVIVSLDEGQISTVLDKTLKQDPTTQG--DKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDEN--RHLNV--AWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGL-TNPKEALLAVTLIRSLGSV----HSIGVVAPYRAQVNLLRQKLDPN----VDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPE 1058
            R+ V +V++   + + L L PE  SS +  C L G W  T VS GD VHV+A         ++ND  GLLVV PDHLVS TSVV+SLFC+R+AVL E+F+G E  + +M  G+L+HEL Q+ + H + ++ +++ R +V+L + +    +  L ++  ++  E+  +LPHI  + + Y+L  + P    A +  +            ++E V DIE+NIW P+ G+KGK+DLTV V +H R +  + ++  PLELKTG+P+ S EH+GQV +Y+MMM++R  DPE GLLLYL+    ++        +RGL+QLRNEL +H      D     A     LPEPI+ KRAC +CPHL++C++ Q+ +E   P+ E H MS LVP+TL HL    L +F++W  +  LE   A+ +      W +    RE +   L+ + L +      Q D    + TF ++S+ S + L  +     + V++S D    E+A+A G ++S+    +  V DK L      QG    ++ +D       +A N VNLA+LM+  P+A+++R+++I RK   +   L K +    + I++ LN  QQRA+ K LM  D++  +GMPGTGKT  IV+LVR++V  G ++LLTSYTHSAVDNILLKL  H  +F+RLG L RIHP ++ F +E  +++    +S+E + + +++ P+VATTCLG+NH   +KR FD+CI+DEASQ   +++LG L HC +FVLVGDP QLPPVVQS +AR+LGM  SLFS L  P N + LNIQYRMN+ IM+ +N LTY G L+CGS E +  TLTL + +  RH     +W   AL+ +L+ SV+ ++T  +P ++  +  GL +NP E  L   L   L        +IGV+ PYR QV+LLR+ L  +    ++VNTVDQ+QG+DK+ +++   R+     +G       +IL DARRLNVAITRAK K I++G   TL+ Y P  +LL+ L E   + L PE
Sbjct:  451 RYRVASVQKSADQGVLLRLNPEDDSSSLKTCSLQGFWTDTLVSEGDNVHVIA--SFVNGHCVINDEYGLLVVNPDHLVSSTSVVSSLFCMRKAVLMEKFRGWEKGNLSMLQGSLIHELFQEVVQHKIVSQDEMKRRLKVLLNQQSSLHEMYGLGITETELETEMMSYLPHIHEWIQHYML--SGPSQLKADNCNENTDLI-------KIEAVQDIEDNIWCPKFGIKGKIDLTVDVTIHSRGKSQKKTV--PLELKTGKPTFSMEHQGQVTLYTMMMSDRSTDPEEGLLLYLQGGPQMKRFSTEHRNVRGLIQLRNEL-SHYTGKVLDMGQNMAPRSAHLPEPISNKRACTKCPHLLSCSLYQRAIEDYTPSSENHPMSILVPETLNHLSSDHLAYFKNWILLLNLELS-ATHQKYGTSFWNEDSLLREKKGICLSGMTLRSSVKHSKQLDSGQWVMTFQKNSSASFDNLKNIGLNPCDFVLISKDGICQEVAIAMGTVLSVLNNSVEVVTDKDL---TMRQGWEHMVFRIDLNVSFSVIAVNFVNLARLMSPDPQAEKIRSFVIDRKQPKYLNRLDKQVVLNGREIMKCLNKPQQRAVLKTLMCKDYIMWRGMPGTGKTLAIVSLVRILVKFGYSVLLTSYTHSAVDNILLKLLNHNVDFIRLGHLGRIHPQIQPFCSEKLTKD---VNSVEELTNFYLSKPVVATTCLGINHVLFRKRKFDFCIIDEASQILQVASLGPLLHCHRFVLVGDPQQLPPVVQSKQARDLGMAESLFSRLSTPDNTIDLNIQYRMNSEIMSLSNLLTYNGALECGSEETANATLTLFNTSFVRHFPSLDSWPMIALAAELKYSVVVLNTDLVPAKEACNLQGLVSNPVEVELVTQLALLLLKGGLEQKNIGVITPYRRQVHLLREALGAHNVCELEVNTVDQYQGRDKEAVIFSCVRSNQENSSG-------EILHDARRLNVAITRAKHKLIIIGSKMTLLFYEPFRQLLSALKECQLLDLPPE 1436          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|957852740|ref|XP_014676403.1| (PREDICTED: DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X2 [Priapulus caudatus])

HSP 1 Score: 683.715 bits (1763), Expect = 0.000e+0
Identity = 408/1018 (40.08%), Postives = 589/1018 (57.86%), Query Frame = 0
Query:   72 PALAAAYGRHEVLAV----ERLLSELQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQ-AAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGR-SSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHLR---PSTPDGSAWP-ALPEPINLKRACAQCPHLMTCAISQK-LESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLV-AQSDRVTHL------HTFGRHSNSTE--TLMGVFQTGETVVLSSD--TELALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLT-NPKEALLAV----TLIRSLGSVHSIGVVAPYRAQVNLLRQKL----DPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPE 1058
            P  AA YGRH V  V    E+  +EL L  R +       +C L G W  T VS GD+VHVLA+R  +G  Y+VN+  GL+VV PD L+SGT+VV++++C R+ VL +RF+ L+  +  M  G+++H   Q+ +   +  RS + +  + V+        +  L++   +V  E++ ++  +Q +   ++ G   +       H   G           +V  V DIEENIWSP+ G+KGK+DLTV VK+H R +  R    ++PLELKTG+ S SAEH+GQV +YSMMM++RR +PE GLLLYL+  ++  V A    +RGLVQLRNEL  HL        D +  P +LP PI+  R+C++CP L+ C + Q+ +E + P   HAM  L+  TL+HL +  + ++  W  M  LE +  +++  L D+WC T  +RE +  A A L L+    D+ + L      HTF RH N T+    M     G++VV+S D   E+A++ G+I  +    +  VLD+ L+ D   +G  +Y +D  +   +M S+  NL++LM D P + +LR  +   +       L KD+    K +L+ LN +QQRA+FK+LMA++++ +KG PG GKT+ IVAL+  +V LG ++L+TSYTHSAVDN+LLKL+    +FLRLGR SRIH D+   SAE  +       S++ + D + +  +VATTCLG+ H    +R FDYCIVDEA+Q    + LG LF  ++FVLVGDP QLPPV++S  A+ +GMD SLF  L++PS  V L++QYRMN+ I   AN +TY G L C S  ++   LTL+      NV WLA  L   LE S  F+DT  +P     D   +  N  E  LA     TLI++      IG++APYR QV L++  L    D  V+VNTVDQ+QG+DK V++    RT    E  V       IL D RRLNVAITRAK K I++G   T+ +Y P+  L+  L +   V L  E
Sbjct:  590 PVPAAKYGRHTVSDVQPCPEQGFTELTL-TRDDRKLERPEKCILQGVWQQTPVSLGDVVHVLAKRDGSGF-YVVNNTDGLIVVNPDTLLSGTTVVSAVYCRRRCVLGQRFRDLDAGNIYMLHGSVIHAFFQEAVLKRMFDRSDLGKIAEKVIGEEQFLHDMYGLNVDEREVMSEIDKYISQVQNWAANHMSGIFGSSAQQDERHKKNGDDI--------KVCAVKDIEENIWSPKYGVKGKIDLTVEVKIHARSKSSRPYKKVVPLELKTGKASFSAEHKGQVTLYSMMMSDRRDNPEEGLLLYLKEGAMVSVPAHPASVRGLVQLRNELAAHLSRFVSRCDDRAPRPMSLPPPIDNVRSCSRCPQLLNCTLYQRSIEISTPPAGHAMESLLRDTLSHLSQCHMDYYSHWVTMLLLEMETEAQRRNLVDIWCMTGWEREQKGQAFAGLVLLDGNYDQDSELGSRQFAHTFKRHKNCTQHQLTMSGLHAGDSVVVSLDLPQEVAISSGIIREVCHSSLQLVLDRDLRLDREWRG-HVYRVDLCDSFSTMISSFTNLSRLMLDTPHSTRLREVVADLRSPRERSTLGKDVVKRCKHVLKPLNKLQQRAVFKVLMADEYLLIKGFPGAGKTSTIVALIEALVLLGNSVLVTSYTHSAVDNLLLKLKQKGVDFLRLGRRSRIHADILPHSAEVLT----CGLSVQQLTDFYASKMVVATTCLGVGHVLFTRRRFDYCIVDEATQVMQPACLGPLFCADRFVLVGDPRQLPPVIRSKEAKSMGMDESLFVRLDKPSCTVELSLQYRMNSEITRIANAITYKGALSCSSNAVASACLTLSVPKLTTNVPWLAEILDCHLEKSAQFLDTDQVPALQSYDSKKMVKNETEGKLATIISATLIKAGVKPCDIGIIAPYRNQVTLIKSMLSLRDDTLVEVNTVDQYQGRDKSVVIVSFVRT-DATEGSVSS-----ILRDTRRLNVAITRAKHKLILLGSLSTMRRYEPLANLIHSLRDDQVVALPTE 1586          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|957852732|ref|XP_014676402.1| (PREDICTED: DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X1 [Priapulus caudatus])

HSP 1 Score: 683.33 bits (1762), Expect = 0.000e+0
Identity = 408/1018 (40.08%), Postives = 589/1018 (57.86%), Query Frame = 0
Query:   72 PALAAAYGRHEVLAV----ERLLSELQLELRPEGSSSEVVQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQ-AAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGR-SSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHLR---PSTPDGSAWP-ALPEPINLKRACAQCPHLMTCAISQK-LESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLV-AQSDRVTHL------HTFGRHSNSTE--TLMGVFQTGETVVLSSD--TELALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVAWLARALSPKLEDSVLFVDTQNIPTEDVSDQSGLT-NPKEALLAV----TLIRSLGSVHSIGVVAPYRAQVNLLRQKL----DPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTLVPE 1058
            P  AA YGRH V  V    E+  +EL L  R +       +C L G W  T VS GD+VHVLA+R  +G  Y+VN+  GL+VV PD L+SGT+VV++++C R+ VL +RF+ L+  +  M  G+++H   Q+ +   +  RS + +  + V+        +  L++   +V  E++ ++  +Q +   ++ G   +       H   G           +V  V DIEENIWSP+ G+KGK+DLTV VK+H R +  R    ++PLELKTG+ S SAEH+GQV +YSMMM++RR +PE GLLLYL+  ++  V A    +RGLVQLRNEL  HL        D +  P +LP PI+  R+C++CP L+ C + Q+ +E + P   HAM  L+  TL+HL +  + ++  W  M  LE +  +++  L D+WC T  +RE +  A A L L+    D+ + L      HTF RH N T+    M     G++VV+S D   E+A++ G+I  +    +  VLD+ L+ D   +G  +Y +D  +   +M S+  NL++LM D P + +LR  +   +       L KD+    K +L+ LN +QQRA+FK+LMA++++ +KG PG GKT+ IVAL+  +V LG ++L+TSYTHSAVDN+LLKL+    +FLRLGR SRIH D+   SAE  +       S++ + D + +  +VATTCLG+ H    +R FDYCIVDEA+Q    + LG LF  ++FVLVGDP QLPPV++S  A+ +GMD SLF  L++PS  V L++QYRMN+ I   AN +TY G L C S  ++   LTL+      NV WLA  L   LE S  F+DT  +P     D   +  N  E  LA     TLI++      IG++APYR QV L++  L    D  V+VNTVDQ+QG+DK V++    RT    E  V       IL D RRLNVAITRAK K I++G   T+ +Y P+  L+  L +   V L  E
Sbjct:  596 PVPAAKYGRHTVSDVQPCPEQGFTELTL-TRDDRKLERPEKCILQGVWQQTPVSLGDVVHVLAKRDGSGF-YVVNNTDGLIVVNPDTLLSGTTVVSAVYCRRRCVLGQRFRDLDAGNIYMLHGSVIHAFFQEAVLKRMFDRSDLGKIAEKVIGEEQFLHDMYGLNVDEREVMSEIDKYISQVQNWAANHMSGIFGSSAQQDERHKKNGDDI--------KVCAVKDIEENIWSPKYGVKGKIDLTVEVKIHARSKSSRPYKKVVPLELKTGKASFSAEHKGQVTLYSMMMSDRRDNPEEGLLLYLKEGAMVSVPAHPASVRGLVQLRNELAAHLSRFVSRCDDRAPRPMSLPPPIDNVRSCSRCPQLLNCTLYQRSIEISTPPAGHAMESLLRDTLSHLSQCHMDYYSHWVTMLLLEMETEAQRRNLVDIWCMTGWEREQKGQAFAGLVLLDGNYDQDSELGSRQFAHTFKRHKNCTQHQLTMSGLHAGDSVVVSLDLPQEVAISSGIIREVCHSSLQLVLDRDLRLDREWRG-HVYRVDLCDSFSTMISSFTNLSRLMLDTPHSTRLREVVADLRSPRERSTLGKDVVKRCKHVLKPLNKLQQRAVFKVLMADEYLLIKGFPGAGKTSTIVALIEALVLLGNSVLVTSYTHSAVDNLLLKLKQKGVDFLRLGRRSRIHADILPHSAEVLT----CGLSVQQLTDFYASKMVVATTCLGVGHVLFTRRRFDYCIVDEATQVMQPACLGPLFCADRFVLVGDPRQLPPVIRSKEAKSMGMDESLFVRLDKPSCTVELSLQYRMNSEITRIANAITYKGALSCSSNAVASACLTLSVPKLTTNVPWLAEILDCHLEKSAQFLDTDQVPALQSYDSKKMVKNETEGKLATIISATLIKAGVKPCDIGIIAPYRNQVTLIKSMLSLRDDTLVEVNTVDQYQGRDKSVVIVSFVRT-DATEGSVSS-----ILRDTRRLNVAITRAKHKLILLGSLSTMRRYEPLANLIHSLRDDQVVALPTE 1592          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|1207987452|ref|XP_021343498.1| (DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X1 [Mizuhopecten yessoensis] >gi|1207987454|ref|XP_021343499.1| DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X1 [Mizuhopecten yessoensis])

HSP 1 Score: 674.855 bits (1740), Expect = 0.000e+0
Identity = 389/1036 (37.55%), Postives = 603/1036 (58.20%), Query Frame = 0
Query:   71 PPALAAAYGRHEVLAVERLLSELQLELRPEGSSSEVVQ-CRLAGSWLHTRVSAGDLVHVLAERQSAGNEYL---VNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVL-GQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHL----RPSTPDGS---AWPALPEPINLKRACAQCPHLMTCAISQKLESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVTHLHTFGRHSNSTETLMGV--------------------FQTGETVVLSSD--TELALAQGVIVSLDEGQISTVLD-KTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDE-------NRHLNVAWLARALSPKLED----SVLFVDTQNIPTEDVSDQSG-LTNPKEALLAVTLIRSLG----SVHSIGVVAPYRAQVNLLRQKL--------DPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYL 1047
            PP +   +GRH V ++ R    + LEL  E  + ++ + C L   W  T ++ GD+VHV+ +     ++++   + D+ GL+VV PD L+SGTSVV+ +FC+R+++LNE+FKG +  +  M  G+++H L Q  L   ++ ++++    ++++ ++     +  + ++  +V +E++ ++P +Q + E+Y   GQ             GA           + ++ DIEENIWSPR G+KGK+DLTV V+   R +     L +PLELKTGRPS S EH+GQV +YSMM ++RR DP+ GLLLYL+  S++ + A     RGL+QLRNE+   L    + S  DG    ++  LP+PIN  R C +CPHL+ CA  Q++E       HAMS LVP TLAHL    L++F  W  M  LE+Q A+ +S L+ +WC+T  QREA    +  L LV   +  T      + S + + +  +                      +G+ V++SS+  + +A+  G + +L    +  V + ++L +    +G   + LD+Y+   + A    NL++LMAD PR+ +LR+ +I R    F   L K      K I + LN  Q+ +I K+LM+ D++ +KG PGTGKT+ IVALV++ + LG ++LLTSYTHSAVDNIL KL+     F+RLG+ ++IHPD+R FSA+H ++     +++  +++ + +  IVAT+CLG+NHP   +R FD CIVDEASQ    + LG LF  ++FVLVGDP QLPPVVQS  AR +GMD SLF  L++      LN+QYRMN+ IM+ +N L Y G L+CG+  +++  L + D        ++H    WL + L   L+D    + +F++T N+P  +  D+SG +TN  EA +   L+ +L     SV  IGV+APYR QVN++R  L          +++VNTVDQ+QG+DK+VIL    R+     +  +  K   +L D RR+NVA+TRAK K +++G   +L  YPP+  ++  L
Sbjct:  759 PPCVH--FGRHTVKSINRTRDNVTLEL--EDFAEKIPRLCILEDFWYDTHITEGDIVHVIGQF----DDHMTCRITDKSGLIVVNPDRLLSGTSVVSGVFCMRKSILNEKFKGCDRGNVQMLYGSIIHCLFQQVLKKQIQDKARILTEAELIIKQNKTVHDMYGMGVTEGEVLEEIKKYIPQLQKWLEQYTSSGQTM----------LGAQTKKQGDDDVLITKIKDIEENIWSPRFGVKGKIDLTVEVRKKSRPKGLGEKLTIPLELKTGRPSFSLEHKGQVTLYSMMSSDRRADPKQGLLLYLKEPSMKLIPADHLSQRGLIQLRNEMAHFLDQQVKRSIEDGKTVFSFGRLPDPINNSRTCPKCPHLLHCAAFQRVEERSLPSSHAMSTLVPDTLAHLSPSHLEYFTHWCLMLDLESQ-ANIRSGLRKIWCKTGPQREALGECICRLTLVMDENSTTKCSLVDQKSTADDEMCFIKFTRNWSKNRGFSKDLRTVGLMSGDYVIVSSEEPSMIAVCMGTLQNLGADTLELVTESESLPRLAEIRG-VTFRLDKYDGYSTSAILYTNLSRLMADNPRSVRLRSLIIDRSKSEFLPKLSKSDIESVKKIFKPLNKPQKMSILKVLMSKDYILIKGFPGTGKTSTIVALVKVCLVLGLSVLLTSYTHSAVDNILQKLKKDNVTFVRLGKSNKIHPDIRQFSADHLTKN---LNTVGELREFYHSQKIVATSCLGVNHPLFTQRRFDVCIVDEASQVLQPACLGPLFSADRFVLVGDPKQLPPVVQSQEARSIGMDESLFQHLDDNGATFDLNLQYRMNSAIMSISNTLVYGGALKCGNDMVAISELVIPDPIALQKVVDKH---GWLKQVL---LDDPDYKAAVFLNTSNMPARETRDKSGFITNVGEAKIITILVEALTAAGVSVEEIGVIAPYRNQVNVIRDTLRNTHKTGTQGHIEVNTVDQYQGRDKEVILISFARSFA--SSADQQSKAGQLLKDVRRINVAVTRAKHKLLLVGDKISLQSYPPLVTIMDEL 1763          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|1207987456|ref|XP_021343501.1| (DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X2 [Mizuhopecten yessoensis])

HSP 1 Score: 674.855 bits (1740), Expect = 0.000e+0
Identity = 389/1036 (37.55%), Postives = 603/1036 (58.20%), Query Frame = 0
Query:   71 PPALAAAYGRHEVLAVERLLSELQLELRPEGSSSEVVQ-CRLAGSWLHTRVSAGDLVHVLAERQSAGNEYL---VNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVL-GQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHL----RPSTPDGS---AWPALPEPINLKRACAQCPHLMTCAISQKLESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVTHLHTFGRHSNSTETLMGV--------------------FQTGETVVLSSD--TELALAQGVIVSLDEGQISTVLD-KTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDE-------NRHLNVAWLARALSPKLED----SVLFVDTQNIPTEDVSDQSG-LTNPKEALLAVTLIRSLG----SVHSIGVVAPYRAQVNLLRQKL--------DPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYL 1047
            PP +   +GRH V ++ R    + LEL  E  + ++ + C L   W  T ++ GD+VHV+ +     ++++   + D+ GL+VV PD L+SGTSVV+ +FC+R+++LNE+FKG +  +  M  G+++H L Q  L   ++ ++++    ++++ ++     +  + ++  +V +E++ ++P +Q + E+Y   GQ             GA           + ++ DIEENIWSPR G+KGK+DLTV V+   R +     L +PLELKTGRPS S EH+GQV +YSMM ++RR DP+ GLLLYL+  S++ + A     RGL+QLRNE+   L    + S  DG    ++  LP+PIN  R C +CPHL+ CA  Q++E       HAMS LVP TLAHL    L++F  W  M  LE+Q A+ +S L+ +WC+T  QREA    +  L LV   +  T      + S + + +  +                      +G+ V++SS+  + +A+  G + +L    +  V + ++L +    +G   + LD+Y+   + A    NL++LMAD PR+ +LR+ +I R    F   L K      K I + LN  Q+ +I K+LM+ D++ +KG PGTGKT+ IVALV++ + LG ++LLTSYTHSAVDNIL KL+     F+RLG+ ++IHPD+R FSA+H ++     +++  +++ + +  IVAT+CLG+NHP   +R FD CIVDEASQ    + LG LF  ++FVLVGDP QLPPVVQS  AR +GMD SLF  L++      LN+QYRMN+ IM+ +N L Y G L+CG+  +++  L + D        ++H    WL + L   L+D    + +F++T N+P  +  D+SG +TN  EA +   L+ +L     SV  IGV+APYR QVN++R  L          +++VNTVDQ+QG+DK+VIL    R+     +  +  K   +L D RR+NVA+TRAK K +++G   +L  YPP+  ++  L
Sbjct:  758 PPCVH--FGRHTVKSINRTRDNVTLEL--EDFAEKIPRLCILEDFWYDTHITEGDIVHVIGQF----DDHMTCRITDKSGLIVVNPDRLLSGTSVVSGVFCMRKSILNEKFKGCDRGNVQMLYGSIIHCLFQQVLKKQIQDKARILTEAELIIKQNKTVHDMYGMGVTEGEVLEEIKKYIPQLQKWLEQYTSSGQTM----------LGAQTKKQGDDDVLITKIKDIEENIWSPRFGVKGKIDLTVEVRKKSRPKGLGEKLTIPLELKTGRPSFSLEHKGQVTLYSMMSSDRRADPKQGLLLYLKEPSMKLIPADHLSQRGLIQLRNEMAHFLDQQVKRSIEDGKTVFSFGRLPDPINNSRTCPKCPHLLHCAAFQRVEERSLPSSHAMSTLVPDTLAHLSPSHLEYFTHWCLMLDLESQ-ANIRSGLRKIWCKTGPQREALGECICRLTLVMDENSTTKCSLVDQKSTADDEMCFIKFTRNWSKNRGFSKDLRTVGLMSGDYVIVSSEEPSMIAVCMGTLQNLGADTLELVTESESLPRLAEIRG-VTFRLDKYDGYSTSAILYTNLSRLMADNPRSVRLRSLIIDRSKSEFLPKLSKSDIESVKKIFKPLNKPQKMSILKVLMSKDYILIKGFPGTGKTSTIVALVKVCLVLGLSVLLTSYTHSAVDNILQKLKKDNVTFVRLGKSNKIHPDIRQFSADHLTKN---LNTVGELREFYHSQKIVATSCLGVNHPLFTQRRFDVCIVDEASQVLQPACLGPLFSADRFVLVGDPKQLPPVVQSQEARSIGMDESLFQHLDDNGATFDLNLQYRMNSAIMSISNTLVYGGALKCGNDMVAISELVIPDPIALQKVVDKH---GWLKQVL---LDDPDYKAAVFLNTSNMPARETRDKSGFITNVGEAKIITILVEALTAAGVSVEEIGVIAPYRNQVNVIRDTLRNTHKTGTQGHIEVNTVDQYQGRDKEVILISFARSFA--SSADQQSKAGQLLKDVRRINVAVTRAKHKLLLVGDKISLQSYPPLVTIMDEL 1762          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|998515038|ref|XP_015518231.1| (PREDICTED: DNA replication ATP-dependent helicase/nuclease DNA2 [Neodiprion lecontei])

HSP 1 Score: 666.381 bits (1718), Expect = 0.000e+0
Identity = 386/993 (38.87%), Postives = 585/993 (58.91%), Query Frame = 0
Query:  107 VQCRLAGSWLHTRVSAGDLVHVLAERQSAGNEYLVNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPS------KTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVLGQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHLRPS----TPDGSAWPA--------LPEPINLKRACAQCPH-LMTCAISQKLESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVA----QSDRVTHLHTFGRHSN------STETLMGVFQTGETVVLSSDTELALAQGVIVSLDEGQISTVLDKTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDENRHLNVA--WLARALSPKLEDSVLFV---DTQNIPTEDVSDQ---------SGLTNPKEALLAVTLIRSLGSVHS-IGVVAPYRAQVNLLRQKLDPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMMGHGPTLMKYPPIHELLTYLGETGTVTL 1055
            V   L G W  TR+  GD+V++ A++Q   N+++V++  G +V QPD LVSGTSVV +LFC R+ +L++RFKG+E  +        M IG+LVHEL Q  L   + T+  + +  + ++        + S  M++    +E+ PF+P I  FTE+Y+ G+ +      F+              G++  + DIEE++W P+LG+KGKVD+TV V ++ + R       MPLELKTGRPS S EHRGQVI+Y+MMM     D E+GLLLYLR++ ++E+K    E R L+ LRN L  +L  +     P  S            LPEPIN  RAC  CP+  + CA  +  +S  P + H ++ ++ +   +L    +K+ + W +M  +   +  +   L++LW   P QRE     +++LK++     + +R  H  TF R ++      S  T  G F T E V++S+DT++ +  G ++ L +  I+ +L++ L +    +   ++H+D Y  Q  + +NL N+  L+ D    +++R  +I R P TF K L + +A VA+ +L+ LN +QQRA+ K++ AN+++ +KGMPGTGKT  +VA++ L+V +GK++LLT++THSAVDN+LLKL     +F+RLG  +RI+P L   S    +QE    +SL+     + +  +V  TCLG NHP + +R FD C+VDE++Q    S L  L+   KFVL+GDPDQLPPVV+S+ AR+LGMD SLF  L+  +N V L +QYRMN  IM+ AN +TY GQL  G+ +I + TL + D++  LN +  W+  ALS  L+DSV+ +   DT NI  +D+S +         S L      L  VT++   G V   IGV+APYR QVNLLR  ++ +V+VNTVDQ+QG+DK++ILY  TR+   +   V  +K  +ILDD RRL VAITRAK K I++G   TL ++ P  +L   +     +TL
Sbjct:  416 VAVTLRGFWKDTRLQTGDIVNIQAKKQL--NDWVVDNTSGFVVEQPDFLVSGTSVVGALFCARRGILSDRFKGIESVTDCKQGASVMVIGSLVHELFQKVLKEKIYTKPGITKLLKDLIKSHNTASMLYSAGMAMETCEKEMLPFVPKIFHFTERYIKGEKSKHADENFN--------------GKINVIRDIEESLWVPQLGVKGKVDVTVEVNVNLKPR------TMPLELKTGRPSFSLEHRGQVILYTMMMTVTGQDVEAGLLLYLRDNIMREIKVSHPEQRDLILLRNNLAYYLTRTPKLMKPVNSGVGEESNEDSMELPEPIN-HRACQNCPYSALCCAYLKNDKSFQPTDRHPLTSIIRELDNYLKPEHIKYVKKWVKMLQINEADEVQNQPLRNLWTIPPTQREKNGKCISNLKIIGKVFIECNRFRH--TFTRVNSADFKVTSDLTKFG-FNTMEYVIISTDTKINVCAGTVIELSKDTITVLLERNLVE---KKPKDVFHIDPYVSQSMLIANLSNIGYLLDDNAVTERMRKIVIERAPATFLKKLDRSVAVVAEQVLKPLNKMQQRAVLKVVAANEYLLIKGMPGTGKTQTLVAIIELLVKMGKSVLLTAHTHSAVDNVLLKLIETNVDFVRLGSTNRINPKLLSKSEAMLTQECRTPESLDTA---YNSKNVVCVTCLGANHPLLGRRIFDVCLVDESTQVLQSSLLRPLYSSSKFVLIGDPDQLPPVVKSNEARKLGMDQSLFERLDNENNTVTLTLQYRMNQRIMSVANQITYKGQLTIGADDIGMATLHIPDKSV-LNSSKNWVKSALSTDLDDSVVVLHTGDTHNIFKDDISPENDNYRERKCSNLCEAAVILHLVTILMQAGVVAGQIGVIAPYREQVNLLRDIIEQDVEVNTVDQYQGRDKELILYSGTRSNYVR--SVDAEKEFNILDDYRRLTVAITRAKHKLIIVGDIITLKQFVPFKKLFDQIRSKDLITL 1373          
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Match: gi|1205812810|gb|OWF34970.1| (DNA replication ATP-dependent helicase/nuclease DNA2 [Mizuhopecten yessoensis])

HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0
Identity = 383/1017 (37.66%), Postives = 593/1017 (58.31%), Query Frame = 0
Query:   71 PPALAAAYGRHEVLAVERLLSELQLELRPEGSSSEVVQ-CRLAGSWLHTRVSAGDLVHVLAERQSAGNEYL---VNDRGGLLVVQPDHLVSGTSVVASLFCLRQAVLNERFKGLEGPSKTMFIGTLVHELLQDCLAHDVRTRSQVEERFQVVLARSAIRQTILSLDMSLAQVRQEVEPFLPHIQFFTEKYVL-GQAAPPPPPAFHPPQGAPPPPPAVWPGRVEEVCDIEENIWSPRLGMKGKVDLTVRVKLHGRDRLGRSSLIMPLELKTGRPSGSAEHRGQVIMYSMMMAERRPDPESGLLLYLRNSSLQEVKAGIHEMRGLVQLRNELVTHL----RPSTPDGS---AWPALPEPINLKRACAQCPHLMTCAISQKLESAVPAEPHAMSDLVPKTLAHLDEIDLKFFQDWSRMCALEAQEASRKSKLKDLWCQTPRQREAQKSALAHLKLVAQSDRVTHLHTFGRHSNSTETLMGV--------------------FQTGETVVLSSD--TELALAQGVIVSLDEGQISTVLD-KTLKQDPTTQGDKIYHLDRYEYQGSMASNLVNLAKLMADQPRAQQLRAWLIHRKPVTFAKGLPKDIAAVAKPILRSLNPVQQRAIFKLLMANDFVTLKGMPGTGKTTLIVALVRLMVALGKTILLTSYTHSAVDNILLKLRAHESNFLRLGRLSRIHPDLRVFSAEHQSQEGMASDSLENMKDRFMTCPIVATTCLGLNHPAVQKRNFDYCIVDEASQAQLLSALGTLFHCEKFVLVGDPDQLPPVVQSSRARELGMDASLFSCLEEPSNRVALNIQYRMNATIMACANHLTYVGQLQCGSPEISLKTLTLNDE-------NRHLNVAWLARALSPKLED----SVLFVDTQNIPTEDVSDQSG-LTNPKEALLAVTLIRSLG----SVHSIGVVAPYRAQVNLLRQKL--------DPNVDVNTVDQFQGKDKDVILYCTTRTRPPKETGVKGDKCRDILDDARRLNVAITRAKCKFIMM 1028
            PP +   +GRH V ++ R    + LEL  E  + ++ + C L   W  T ++ GD+VHV+ +     ++++   + D+ GL+VV PD L+SGTSVV+ +FC+R+++LNE+FKG +  +  M  G+++H L Q  L   ++ ++++    ++++ ++     +  + ++  +V +E++ ++P +Q + E+Y   GQ             GA           + ++ DIEENIWSPR G+KGK+DLTV V+   R +     L +PLELKTGRPS S EH+GQV +YSMM ++RR DP+ GLLLYL+  S++ + A     RGL+QLRNE+   L    + S  DG    ++  LP+PIN  R C +CPHL+ CA  Q++E       HAMS LVP TLAHL    L++F  W  M  LE+Q A+ +S L+ +WC+T  QREA    +  L LV   +  T      + S + + +  +                      +G+ V++SS+  + +A+  G + +L    +  V + ++L +    +G   + LD+Y+   + A    NL++LMAD PR+ +LR+ +I R    F   L K      K I + LN  Q+ +I K+LM+ D++ +KG PGTGKT+ IVALV++ + LG ++LLTSYTHSAVDNIL KL+     F+RLG+ ++IHPD+R FSA+H ++     +++  +++ + +  IVAT+CLG+NHP   +R FD CIVDEASQ    + LG LF  ++FVLVGDP QLPPVVQS  AR +GMD SLF  L++      LN+QYRMN+ IM+ +N L Y G L+CG+  +++  L + D        ++H    WL + L   L+D    + +F++T N+P  +  D+SG +TN  EA +   L+ +L     SV  IGV+APYR QVN++R  L          +++VNTVDQ+QG+DK+VIL    R+     +  +  K   +L D RR+NVA+TRAK K +++
Sbjct:  759 PPCVH--FGRHTVKSINRTRDNVTLEL--EDFAEKIPRLCILEDFWYDTHITEGDIVHVIGQF----DDHMTCRITDKSGLIVVNPDRLLSGTSVVSGVFCMRKSILNEKFKGCDRGNVQMLYGSIIHCLFQQVLKKQIQDKARILTEAELIIKQNKTVHDMYGMGVTEGEVLEEIKKYIPQLQKWLEQYTSSGQTM----------LGAQTKKQGDDDVLITKIKDIEENIWSPRFGVKGKIDLTVEVRKKSRPKGLGEKLTIPLELKTGRPSFSLEHKGQVTLYSMMSSDRRADPKQGLLLYLKEPSMKLIPADHLSQRGLIQLRNEMAHFLDQQVKRSIEDGKTVFSFGRLPDPINNSRTCPKCPHLLHCAAFQRVEERSLPSSHAMSTLVPDTLAHLSPSHLEYFTHWCLMLDLESQ-ANIRSGLRKIWCKTGPQREALGECICRLTLVMDENSTTKCSLVDQKSTADDEMCFIKFTRNWSKNRGFSKDLRTVGLMSGDYVIVSSEEPSMIAVCMGTLQNLGADTLELVTESESLPRLAEIRG-VTFRLDKYDGYSTSAILYTNLSRLMADNPRSVRLRSLIIDRSKSEFLPKLSKSDIESVKKIFKPLNKPQKMSILKVLMSKDYILIKGFPGTGKTSTIVALVKVCLVLGLSVLLTSYTHSAVDNILQKLKKDNVTFVRLGKSNKIHPDIRQFSADHLTKN---LNTVGELREFYHSQKIVATSCLGVNHPLFTQRRFDVCIVDEASQVLQPACLGPLFSADRFVLVGDPKQLPPVVQSQEARSIGMDESLFQHLDDNGATFDLNLQYRMNSAIMSISNTLVYGGALKCGNDMVAISELVIPDPIALQKVVDKH---GWLKQVL---LDDPDYKAAVFLNTSNMPARETRDKSGFITNVGEAKIITILVEALTAAGVSVEEIGVIAPYRNQVNVIRDTLRNTHKTGTQGHIEVNTVDQYQGRDKEVILISFARSFA--SSADQQSKAGQLLKDVRRINVAVTRAKHKLLLI 1744          
The following BLAST results are available for this feature:
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides)
Total hits: 7
Match NameE-valueIdentityDescription
EMLSAG000000030940.000e+045.71supercontig:LSalAtl2s:LSalAtl2s173:343286:346696:-... [more]
EMLSAG000000094285.841e-3228.44supercontig:LSalAtl2s:LSalAtl2s600:488026:492190:-... [more]
EMLSAG000000036651.552e-2231.40supercontig:LSalAtl2s:LSalAtl2s19:264402:269259:-1... [more]
EMLSAG000000050153.117e-2224.58supercontig:LSalAtl2s:LSalAtl2s260:591600:598646:1... [more]
EMLSAG000000042766.586e-1826.64supercontig:LSalAtl2s:LSalAtl2s224:316115:320975:1... [more]
EMLSAG000000006066.804e-1826.89supercontig:LSalAtl2s:LSalAtl2s109:446994:450007:1... [more]
EMLSAG000000100503.275e-1026.05supercontig:LSalAtl2s:LSalAtl2s662:147778:155854:1... [more]
back to top
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt)
Total hits: 25
Match NameE-valueIdentityDescription
gi|82105075|sp|Q8QHA5.1|DNA2_XENLA0.000e+036.51RecName: Full=DNA replication ATP-dependent helica... [more]
gi|408407614|sp|D3ZG52.1|DNA2_RAT0.000e+036.24RecName: Full=DNA replication ATP-dependent helica... [more]
gi|119368660|sp|Q6ZQJ5.2|DNA2_MOUSE0.000e+035.96RecName: Full=DNA replication ATP-dependent helica... [more]
gi|408360056|sp|Q5ZKG3.2|DNA2_CHICK0.000e+035.61RecName: Full=DNA replication ATP-dependent helica... [more]
gi|408407704|sp|E1BMP7.3|DNA2_BOVIN0.000e+034.89RecName: Full=DNA replication ATP-dependent helica... [more]
gi|119370373|sp|P51530.3|DNA2_HUMAN6.360e-17834.27RecName: Full=DNA replication ATP-dependent helica... [more]
gi|408407615|sp|F6QXW0.1|DNA2_XENTR6.927e-13632.15RecName: Full=DNA replication ATP-dependent helica... [more]
gi|408360057|sp|Q9URU2.2|DNA2_SCHPO5.586e-12031.65RecName: Full=DNA replication ATP-dependent helica... [more]
gi|731738|sp|P38859.1|DNA2_YEAST3.427e-10528.71RecName: Full=DNA replication ATP-dependent helica... [more]
gi|2498040|sp|Q60560.1|SMBP2_MESAU3.333e-3127.97RecName: Full=DNA-binding protein SMUBP-2; AltName... [more]

Pages

back to top
BLAST of dna replication atp-dependent helicase nuclease dna2-like vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR)
Total hits: 25
Match NameE-valueIdentityDescription
gi|919004379|ref|XP_013379222.1|0.000e+041.62DNA replication ATP-dependent helicase/nuclease DN... [more]
gi|1238875841|ref|XP_022251495.1|0.000e+040.83DNA replication ATP-dependent helicase/nuclease DN... [more]
gi|1238875837|ref|XP_022251493.1|0.000e+040.83DNA replication ATP-dependent helicase/nuclease DN... [more]
gi|1238875845|ref|XP_022251497.1|0.000e+040.83DNA replication ATP-dependent helicase/nuclease DN... [more]
gi|957852740|ref|XP_014676403.1|0.000e+040.08PREDICTED: DNA replication ATP-dependent helicase/... [more]
gi|957852732|ref|XP_014676402.1|0.000e+040.08PREDICTED: DNA replication ATP-dependent helicase/... [more]
gi|1207987452|ref|XP_021343498.1|0.000e+037.55DNA replication ATP-dependent helicase/nuclease DN... [more]
gi|1207987456|ref|XP_021343501.1|0.000e+037.55DNA replication ATP-dependent helicase/nuclease DN... [more]
gi|998515038|ref|XP_015518231.1|0.000e+038.87PREDICTED: DNA replication ATP-dependent helicase/... [more]
gi|1205812810|gb|OWF34970.1|0.000e+037.66DNA replication ATP-dependent helicase/nuclease DN... [more]

Pages

back to top
Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
scaffold757_size101632supercontigscaffold757_size101632:13012..16324 +
Analyses
This gene is derived from or has results from the following analyses
Analysis NameDate Performed
maker2018-02-12 .496401
T. kinsejongensis vs L. Salmonis peptides2018-04-19
T. kingejongensis peptided Blastp vs. SwissProt2018-04-19
T. kingsejongensis proteins Blastp vs. NR2018-05-15
Properties
Property NameValue
Note-
Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameSpeciesType
maker-scaffold757_size101632-snap-gene-0.17-mRNA-1maker-scaffold757_size101632-snap-gene-0.17-mRNA-1Tigriopus kingsejongensismRNA


Sequences
The following sequences are available for this feature:

gene from alignment at scaffold757_size101632:13012..16324+

Legend: mRNA
Hold the cursor over a type above to highlight its positions in the sequence below.
>maker-scaffold757_size101632-snap-gene-0.17 ID=maker-scaffold757_size101632-snap-gene-0.17|Name=dna replication atp-dependent helicase nuclease dna2-like|organism=Tigriopus kingsejongensis|type=gene|length=3313bp|location=Sequence derived from alignment at scaffold757_size101632:13012..16324+ (Tigriopus kingsejongensis)
ATGGATTTCACCCGCCGCAAGCTCTCGTCCAAGTCGAACTCCACCTCCAT CTTGGCCAAGCTCAAGAGCCAGGCCCGCCAGTTGGCCCCTCAGCGTCGCT CTACGGCCGTCTTGGTCGAACCCGACACGAGCCGGAGCCCACCCAGCGCG GCTCCGGCGCCCAAAAGAGCCCGAGTGGGCGCCTCAGCCCCGGCGGCGGT CGCCGTCGACCCACCGGCGTTGGCCGCGGCCTACGGGCGTCACGAGGTCC TGGCCGTGGAGCGGCTCTTGTCCGAGCTTCAACTCGAGTTGCGTCCGGAA GGATCCTCGTCCGAGGTGGTCCAGTGTCGCCTGGCCGGCTCTTGGCTCCA CACCCGGGTGTCGGCCGGCGACCTGGTGCACGTGCTAGCCGAGCGTCAGT CCGCGGGGAATGAGTACTTGGTGAATGACCGCGGCGGGTTGCTAGTGGTC CAGCCCGACCATCTCGTGTCGGGCACATCGGTCGTGGCCTCGCTCTTCTG CCTCCGACAGGCCGTGCTCAACGAGCGCTTCAAAGGCTTGGAGGGTGAGT CGAGCAGGTGACGGCCTGAGTCTGGGGCTCCGAACTCACTGACTTCCGCT TCTAGGTCCCTCCAAGACCATGTTCATCGGAACGCTGGTCCACGAGCTGC TCCAAGACTGTCTGGCCCACGACGTGCGGACCCGGAGTCAGGTGGAGGAG CGTTTTCAGGTCGTCCTGGCCCGCTCAGCCATCCGGCAGACGATCCTGTC CCTGGACATGTCCCTGGCCCAGGTCCGACAAGAGGTGGAGCCCTTTTTGC CCCACATTCAATTTTTTACCGAGAAGTAGGTTCCGTCTGCCGGCGCTCCA AGCCCGGTCCGATCCTCATCCTGGTCCATTTTCCCCCCATGTAGGTACGT GTTGGGCCAGGCTGCACCTCCACCGCCGCCGGCTTTTCATCCGCCCCAAG GGGCCCCGCCCCCTCCTCCTGCCGTGTGGCCGGGGCGGGTCGAAGAAGTG TGCGACATAGAAGAGAATATTTGGTCACCCCGCCTGGGCATGAAAGGCAA GGTTGACCTCACGGTCCGGGTCAAGCTCCATGGGCGAGACCGCCTCGGCC GCTCGAGCTTGATAATGCCGCTCGAGTTGAAAACTGGACGGCCTTCGGGC TCGGCCGAACACCGCGGCCAAGTCATCATGTACAGTATGATGATGGCCGA GCGCCGACCTGACCCCGAGTCCGGTCTGTTACTCTACCTGAGGAACTCCT CCCTCCAAGAAGTCAAAGCCGGCATTCATGAGATGCGTGGCCTCGTCCAG TTGCGCAATGAATTGGTGACCCACTTGCGCCCCTCCACCCCGGATGGATC CGCCTGGCCCGCTCTTCCCGAGCCCATCAACTTGAAACGGGCCTGTGCTC AATGTCCCCATCTGATGACGTGTGCCATTTCTCAAAAACTCGAGAGCGCC GTTCCGGCCGAGCCCCATGCCATGAGCGACTTGGTGCCCAAAACTCTGGC CCATCTGGACGAGATCGACTTGAAATTCTTTCAAGACTGGAGCCGCATGT GTGCCCTCGAAGCTCAAGAGGCGAGCCGGAAGAGCAAGCTCAAGGACTTG TGGTGTCAAACGCCCCGTCAGCGAGAGGCTCAAAAATCGGCCTTGGCCCA CCTCAAATTGGTCGCCCAGAGCGACCGAGTGACCCACTTGCACACCTTTG GCCGGCACTCAAATTCGACCGAAACGCTAATGGGCGTGTTTCAGACGGGT GAGACCGTGGTACTGAGCTCAGACACCGAGTTGGCTTTGGCCCAAGGCGT GATCGTGAGTTTGGACGAGGGACAGATATCTACAGTGCTAGATAAAACTC TGAAGCAGGATCCAACCACCCAAGGCGATAAGATTTATCATTTGGACCGG TATGAATACCAGGGCTCCATGGCTTCCAATCTGGTAAACTTGGCCAAGCT CATGGCCGATCAGCCCCGTGCTCAGCAACTTCGAGCATGGCTCATTCATC GCAAACCCGTCACATTTGCCAAAGGTCTGCCCAAGGACATTGCGGCTGTG GCCAAGCCCATTCTCAGATCGCTGAATCCTGTCCAGCAACGAGCCATTTT CAAGCTTCTCATGGCCAATGATTTTGTAACCCTGAAGGGAATGCCAGGCA CGGGCAAGACCACCTTGATTGTAGCGCTGGTGAGATTGATGGTGGCTTTG GGCAAGACCATCCTCCTCACCAGCTACACTCATTCCGCTGTGGACAACAT TCTACTTAAACTTAGGGCGCACGAGTCGAATTTTCTGCGCCTGGGACGCC TGTCCAGAATTCATCCCGACCTGCGTGTATTCAGTGCGGAACACCAAAGT CAAGAAGGTATGGCGAGTGATAGTCTTGAAAACATGAAGGACCGCTTCAT GACGTGTCCCATTGTTGCCACCACTTGCCTGGGACTCAATCACCCGGCCG TACAGAAGCGAAACTTTGACTATTGCATTGTCGACGAGGCCTCGCAGGCT CAGCTACTGTCGGCCTTGGGAACCTTGTTCCACTGTGAAAAGTTCGTTTT GGTGGGCGATCCGGACCAATTGCCTCCCGTCGTCCAAAGCTCGAGAGCTC GAGAGCTCGGTATGGACGCAAGTCTGTTCTCGTGTCTGGAGGAACCATCG AACAGAGTGGCTCTCAACATTCAGTATCGAATGAATGCCACCATCATGGC GTGTGCCAACCACCTGACGTATGTCGGCCAGTTGCAATGTGGGTCCCCCG AAATCAGTCTGAAAACGCTGACGCTCAATGACGAAAACCGACACCTGAAT GTAGCTTGGCTCGCCAGGGCATTATCTCCCAAACTCGAAGATTCGGTCCT CTTTGTGGATACTCAAAATATTCCCACTGAAGACGTGTCTGACCAATCTG GATTGACCAATCCCAAAGAAGCCCTTTTGGCCGTGACCTTGATTCGAAGT CTGGGCAGTGTTCACAGTATCGGTGTAGTTGCGCCTTACCGGGCGCAAGT CAATCTCCTGAGACAGAAATTGGACCCCAACGTCGACGTCAACACCGTAG ACCAATTCCAGGGCAAAGACAAGGATGTTATCCTTTATTGTACGACCCGA ACCAGGCCCCCCAAAGAGACCGGTGTCAAGGGGGACAAGTGTCGGGACAT TTTAGACGATGCCCGCCGTTTGAACGTGGCTATCACTCGCGCCAAGTGCA AGTTTATCATGATGGGTCACGGACCAACTTTGATGAAGTACCCACCCATT CATGAATTATTGACCTACCTAGGAGAGACTGGAACCGTGACACTGGTACC CGAGGATTTATGA
back to top
Synonyms
The feature 'dna replication atp-dependent helicase nuclease dna2-like' has the following synonyms
Synonym
Tk09867
Add to Basket