Query:    4 VTTTGGVAIGLDLGT-----VSRYAGIRYAEAPTGDLRFRPPVAHRSNGAVDASSFGPTAWQPASALEVM-----------LGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVR---------------------------GSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLFDPSRKPLPAAR----LTTRLERLAAAAPSPEQTSAALAAAYEVEVD-----AEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWAS-----PVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVP------APDESAFPSYDPANRAVYDFGTN 491
            +TT  G   G+ L +     V  + GI YA+ P G+LRFR P   +   A D      T   P S ++V+           +      + EDCL L+V  P        V+VWI+GGGF +G+ +  +YD   L    +++ V I YR+  LGFL     D      GN GL DQ+ AL+WV+ NI  FGGD   +TIFGE AG  SVA  L +   R LF   I QS +     P  V ++  +        E++    AL P  +I+  E +R                                ++++       G +   F P++DG  +   P +S++    +   +L G N DE   F     P    +       R + + + +      + A   A   E        + +  R +   ++ D  F  P        A +    Y Y+F+  S     P   G+L   H  E+ FVFG    T  N    D+  + LS+R+   W +FA+ G P            +P + P  + V +   N
Sbjct:   38 ITTRKGKIRGVTLKSATNKEVDAWYGIPYAQPPVGNLRFRHP---KDINAWDG--MKETTKHPNSCIQVVDTFFPGFEGSEMWNTNTEQSEDCLYLSVHAPKPRPTKSAVLVWIYGGGFYSGTSTLELYDPRVLVSEENIIFVGIQYRVASLGFLFFDTEDV----PGNAGLYDQMMALQWVKNNIEAFGGDPDKITIFGEXAGGCSVALHLLSPLSRXLFSXAIMQSSSA--LVPWGVISKKESIRRGRRLAEEMRCPYALVPWGVISKKESIRRGRRLAEEMRCPYGENNTNAMIECLLQKDATELVNQEGSGTVFGISEFPFVPIVDGKFMDKTPEKSLKEKDYKKTNILMGVNKDEGNFFIMYYLPELFKKNENVYINRTDFIRSVSDLNIYVNNAGREAITFEYTDWLNPNDPIKNREAIDRMVGDYQFTCPTADFARIYASTGNNIYMYYFTERSSTSPWPTWSGVL---HGDEIAFVFGEPLNTSKNY---DDSEIALSKRIMSYWANFAKTGNPNVLANGNYSNKIWPLHTPIKQEVLELNAN 571          

Query:    4 VTTTGGVAIGLDLGT-----VSRYAGIRYAEAPTGDLRFRPPVAHRSNGAVDA-SSFGPTAWQPASALEVM-----------LGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGA------VHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADE------WRLFDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSA---LMTDAAFRLPAVRMLEARAESDAPGYHYHFSWAS-----PVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVPAP------DESAFPSYDPANRAVYDFGTN 491
            +TT  G   G+ L +     V  + GI YA+ P G+LRFR P        +DA      T   P S ++V+           +        EDCL L+V  P        V+VWI+GGGF +G+ +  +YD   L    +++ V++ YR+  LGFL     D      GN GL DQ+ AL+WV+ NI  FGGD   +TIFGE AG  SVA  L +   R LF + I QS +      V     + +  +  A++M +   ++    A ++      A E V      +   I G  E       F P++DGS +  +P +S+ +   +   +L G N +E      + L D  +         T   R  +      +     A  +E         P  ++ A   ++ D  F  P        A +    Y Y+F+  S     P   G+L   H  E+ FVFG       N    D+  + LS+RM   W +FA+ G P+         + +P + P  + V +   N
Sbjct:   38 ITTKKGKIRGVTLKSATNREVDAWYGIPYAQPPVGNLRFRHP------RHIDAWEGIKETTRPPNSCIQVVDTLFPGFEGAEMWNVNTEPSEDCLYLSVHVPKPRPTGSAVLVWIYGGGFYSGTSTLEVYDPRVLVSEENIIFVAMQYRVASLGFLFFDTEDV----PGNAGLYDQMMALQWVKNNIEEFGGDPDKITIFGEXAGGCSVALHLLSPLSRNLFSQAIMQSASALVPWGVITKKESIIRGRRLAEMM-SCPYDEKNTKAMIECLRQKDATEMVNQEWIGI---ISGIAEF-----PFVPIVDGSFLDESPGKSLTTKNYKKTNILIGANKEEGNYFIMYYLTDLFKNTESVYVDRTDFIRSVSELNHYVKKMGREAITFEYTDWLNPNDPIKNREAIDRMVGDYQFICPTADFARIYASTGNNVYMYYFTERSSTSPWPTWSGVL---HGDEIAFVFGEALNKSKNY---DKSEIALSKRMMGYWANFAKTGNPSLSADGTWSTNYWPLHTPTKQEVLELNAN 543          

Query:    4 VTTTGGVAIGL-----DLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGL--AALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNAD----EWRLFDPSRKP--LPAARLTTRLERLAAAAPSPEQT----SAALAAAYEVEVDAE---EMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVA-------GGILGSCHALELPFVFGTI 434
            V T+ G  +GL       G    + GIRYA  P  DLRF+ P         V+A   G    Q   A  + LG      DEDCL LNV+TP      R VMV IHGG F+ G G S ++    L E  D+V+V+ NYRLG LGFL       D  +  N G+ DQI AL+WV+ENI  FGGD   VTI GE AGA S   L  +   +GLF  VIA SG        ++  Q      D A  E  A L  ++ D   +I      R +  +++++ +           F P +DG ++   P   + +G    V ++ G   +     +RL   S          +  +L RL     +        + ++   Y V VD E   E  PR  +   +TD  F         A A    P Y Y F +    +          +G  H  E+ +VF  I
Sbjct:   23 VKTSKGPIMGLREDSSSNGYFYSFKGIRYAMPPVEDLRFKAPTELEPWTETVEAVEDGHICPQYDIANSIPLG------DEDCLFLNVYTPKIDSKKRAVMVHIHGGAFILGGGVSHLFGPDYLME-NDIVLVNFNYRLGALGFLTT----KDTMETANNGIKDQIMALKWVKENIDKFGGDPNKVTIIGEDAGAASATILSMSPAAQGLFQGVIALSG-------NALCDQFIQNNPDEAAKELAARLECSSTDGKDIIECIS--RKTQQDIVEKSNSMMMFYTFPRWFAPNVDGDILPDRPENLLSNGQFSKVPIVLGQTKNGGAFYYRLTINSFNNGGYDDNFIDHKLPRLLPVMTNYNSKLYPITRSIRKRYFVNVDMENEDEFRPRYIE--FLTDMLFTKCTDEFARAIANHSVPTYEYLFDYRGQYSIVNFQGEQVDMGVVHGDEMQYVFHNI 459          

Query:   22 YAGIRYAEAPTGDLRFRPPVAHRSNGAVDASSFGPTAWQ----------PASALEVMLGGKQEARD----EDCLRLNVWTPGATGADR------------PVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGN-VLDRIDGAHELGPNLMAFQPVIDGS-LISAAPIESIRSGVGRSVALLTGTNADEWRLFDPSRKPLPAAR----LTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQ--SALMTDAAFRLPAVRMLEARAESDAPGYHYHFS------------------WASPV-------AGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVP 468
            + GI YA  PTG+ RFR P  +            PT W+          PA   ++    K    D    EDCL LN+++P +                 PVMVWIHGG FM+G+ S   Y+      + D+++V I+YRLGPLGFL+LG    ++A  GN G+ DQI AL W+Q+NI  FGGD   VTIFGES+GA+SV   ++    + LF   I QSG+++  T      +T    M  A + ++  +  +D    I      +    N  L   +      P    + PV++GS L+     E+ +S   R   ++ GT ++E      SR  L        ++   E         E         Y    + +   P   Q  S L++D  +  P    ++  A   +P Y+Y +                   W   V       +G   G+ HA ELPF+F       +   V ++    +   M D W +FA  G P
Sbjct:   55 FYGIPYALPPTGERRFRSPEPY------------PTPWKRTLQAGRSYPPACPQQLRSYFKSLLWDVEGNEDCLYLNIFSPDSASLQLSNESPPSQENLFPVMVWIHGGNFMSGTASD--YESIYFMTK-DIILVMISYRLGPLGFLNLG---EEYA-RGNQGIEDQILALSWIQDNISSFGGDPQRVTIFGESSGAISVLHHMSVPMSKLLFQSAIIQSGSIYQPT----IKETFMMEMHEAWIAEMGCIGVIDTQECIQKLPLAKIVNKNPFLSDCNLKKNGHPFPNPWFPVLEGSYLLKEVSAENKKSHAPR---VMIGTTSNE-GFLATSRFMLQNNYTEGFMSKWEECFKLNTAGDESYDLEPVMDYYFGSNKKPDFPSQVQNFSNLISDFWYNGPTFETVKEIANKGSPVYYYLYDHDGFLSMTDSLSRASYDYWKFIVRYAFGQESGKTNGASHADELPFLFREYPRNLLKRPVDEK----MWRLMIDVWTNFATSGDP 529          

Query:   17 GTVSRYAGIRYAEAPTGDLRFRPPVAH-RSNGAVDASSFGPTAWQPASAL-EVMLGGKQEARDEDCLRLNVWTPG-ATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGA 217
            G +  + GIR+   P GDLRF+ PV   R +G  +A   G    Q      +V +G      +EDCL LNV++   A    RPV+VWIHGG F+ G  +   Y+   L +  D+V+V+I YRLG  GFL       D    GN G+LDQ+AAL+WV+ NI  F GD  ++TI G+ AG  SV   + ++  RGLFHR I+ SG+
Sbjct:  107 GRILAFRGIRHVRPPVGDLRFKAPVPFPRWDGIREAKKNGHFCPQHMYYKPDVWIG------EEDCLWLNVFSRDLAVNKKRPVIVWIHGGNFVRGXAAD--YEPDYLLDE-DIVLVTIQYRLGMFGFLS----SEDQYAPGNYGMLDQVAALQWVKTNIDAFSGDVNHITIMGQQAGGASVHYHMLSSLSRGLFHRAISLSGS 297          

Query:   47 GAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPG----ATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGT 316
            G  DASS  P   +P   +    G      +EDCL LNV+TP           PV+VWI+GG ++ G  S   Y    L E G VV+V++NYRLGPLGFL LG+        GN+GL DQ  A+EW++ +IG FGGDA  +T+ G  AG++ +   + +    GLFH+ I  SG                       V +       DPA+L +  E+                        F    D S  S + +E+I++G    + +L GT
Sbjct:    7 GTRDASSPCP---KPVQFIPNYGGISSVIGEEDCLYLNVYTPDLPVTENQKKFPVIVWIYGGNYLWGDASERFYFPKYLIESGSVVIVTLNYRLGPLGFLTLGNE----TVPGNMGLWDQRLAMEWIRTHIGNFGGDADEITLMGHDAGSVCITNHMVSKSSAGLFHKAICMSGTF---------------------VSEKFSFDVSDPASLNSIKEE------------------------FAKECDKSFFSESQLETIKTGEFNKMPILMGT 228          

Query:    3 EVTTTGGVAIGLDL----GTVSRYAGIRYAEAPTGDLRFRPPVAHRSNGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGAD---RPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNA 221
            EV T+ G   G  L      +  + G+ YA+ P      +P    +  G +D +      +QP + +            +DCL LNV+TP          PV+V+ HGG F+ G   + IY    L    ++V+V++N+RLGP GFL   + D      GN G+ DQI +L WVQ +I  FGG + NVTI G+ AG MS    LA+   +GLFH++I  SGAV  A
Sbjct:   16 EVITSLGKLKGKTLLMNDKHIYSFTGVPYADKPQRFSLAKP--CSKWTGTLDCTKESKMGYQP-NPMFFESTFLYHGFPDDCLYLNVFTPILKEDSFDLLPVIVYFHGGAFILGGNDTKIYGPEILLSTQNMVLVTVNFRLGPFGFLSFQNSDC----PGNQGMHDQILSLMWVQSHIHHFGGTSSNVTIMGQXAGGMSSLYHLASPLSKGLFHKIICLSGAVMYA 234          

Query:   22 YAGIRYAEAPTGDLRF-RP-PVAHRSNGAVDASSFGPTAWQ-------PASALEVMLGGKQEARDEDCLRLNVWTP-GATGADR-PVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMS-VATLLAAAGDRGLFHRVIAQSGAVHNATPASVAA--QTTAKVMDAA--GVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPI-----ESI--RSGVGRSVALLTGTNADEWRLFDPS--RKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQS--------ALMTDAAFRLPAVRMLEARAESDAPGYHYHFSW--------------------ASPVAGGI-------LGSCHALELPFVF--GTIGATGMNSFVGD-EPPVGLSERMQDTWLHFARHGVPAP------DESAFPSYDPANRAVYDFGTNDELAE 496
            Y G+ YA  P G+ RF RP P ++   G  D +   P   Q       P   + V          EDCL LN+  P   T  +R PV++W+HGG +   SGS   ++     +  +V+ + INYRLG +GFL L   ++D A  GNLGL DQ  A++W+++ I    G+   +T+ G  +GA S +  L++    +G F R+I QSG+    T    A   +  AK + A+    ++I       PA ++    + +    N+++++       PN   + PVID    +  P+     E+I   +   RS+ +LTG+ A+E  L      + P   A+ T  L  L       E  S        VE+  +  +P+   S        A+ TD  F     R ++       P Y Y + +                     S  + GI        G+CH  EL  +F  G + A   +  + D +  VG S  +   W++FAR G P P      D S + S   +N  V +  T   + E
Sbjct:   61 YFGLPYALPPLGERRFARPEPYSNAWEGIRDGTQSPPICVQQDIHRNNPNDTIGV----------EDCLVLNINQPLTCTRENRCPVIIWLHGGSYALLSGSPYTFNPLYFMDH-NVIFIGINYRLGAMGFLTL---ETDEA-PGNLGLRDQSLAIKWIRDEIDNLYGNKDQITLMGHGSGAHSALIHLVSPFNKKGTFTRIITQSGSPFEDTNLRFAKSRKEYAKKLAASVGCTKEILKCLRSRPADIL----QTKVQTFNIINQV-----FTPN--PWVPVIDIKF-AHDPVLPDYPENIVKNTNFSRSIPILTGSVAEEGMLLMKRFFQHPELFAQFTRTLPFLLFNL---EDESVTPKVQDLVEIVKKFFIPKGQLSYSQNKQIIAMFTDMVFYGKIGRAIQL-LRDHGPIYQYIYKYFGTHSFGDLSFYSDFKLGLKLSLQSRGIGLFMRNGFGTCHGDELFDIFKIGFLKAPMSSGPISDFDKSVGQS--LITMWINFARTGNPTPMGYFLDDNSKWLSIQESNGMVAEIKTKTRMIE 571          

Query:   38 RPPVAHRSNGAVDASSFGPTAWQPASALEVMLGGKQEA--RDEDCLRLNVWTPGATGADR---PVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGA 217
            +PP AH    + +A  + P   QP       +G  + +   DE+CL LNV+TP          PVM +IHGG F  GSG+   + G  L+  G VVVV+INYRLG LGFL  G    D    GN GLLDQ  AL+WV +NI  F GD   +T+FG  AG  S   L      + +  RVI+ SG+
Sbjct:  198 KPPRAHGGWQSYNAVDWAPVCPQPIR----YVGATKNSPLMDENCLFLNVFTPTVESGQSQLFPVMFYIHGGEFQHGSGNE--FSGHQLSYWGRVVVVTINYRLGALGFLSTG----DQHAPGNYGLLDQAMALKWVYDNIYAFQGDREKITVFGPGAGGASAGILAVMPKTKNMVRRVISMSGS 372          

Query:   78 EDCLRLNVWTP----GATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDR--GLFHRVIAQSGA 217
            EDCL L + TP           PVM ++HGGGF   SG+    +   L +  DV+VV+INYR+G LGFL L   DSD   AGN G+LD + ALEWVQ+ I  FGGD   VTIFGESAG+ ++  LL +   R   LF   I QSG+
Sbjct:  190 EDCLHLTISTPVKPPPKESKGYPVMFFVHGGGF--SSGTHLHSEADRLGDAADVIVVAINYRVGILGFLCL---DSD-ESAGNQGMLDILLALEWVQKYIEHFGGDKERVTIFGESAGSATIGHLLLSPSTREKNLFKYGIGQSGS 329          

Query:   19 VSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQP-------ASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADA-GNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALI-----AAGEKVRGSGGNVL--DRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLFDPSRKPLP---AARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVPAPDESAFPSYDPANRAVYDF 488
            ++ + GI YAE P G  RF  P   R  +G  DA+ F  TA +P       A  +E  + G      +D L LNVWTP       PVMVWIHGG F  GSGS P+YDGA+ A  G VV VS NYRLG +GF       +D  DA  N GLLDQIAALEWV++NI  FGGD GNVT+FGESAGAMSV TL+A    RGLF R I QSGA + A  A  A    A +    GVE  A   A  P A +        ++++G+    +  +RI G    G  L+ F PVIDG L+S  P E+I  G G  V LL GT  DE+RLF      LP      +TT L +            A  A AY  E   EE  P    ++++TD  FR+PA+R+ E+R ++ A  + Y F+W +P   GILG+CHA+ELPFVF T+      S VG  PP  L+E + + W+ FA  G P      +P+++P  R+V  F
Sbjct:   20 IAVFRGIPYAEPPVGAHRFTAPRPPRPWDGVRDATEFSATAPRPPYPEAIGALLIERFIPG------DDYLTLNVWTPDPNAVGLPVMVWIHGGAFTNGSGSEPVYDGAAFARDG-VVFVSFNYRLGIIGF-------ADLPDAPSNRGLLDQIAALEWVRDNIARFGGDPGNVTVFGESAGAMSVCTLMATPRARGLFRRAILQSGAGNMAVAAEDATTIAAVIAHRLGVEPTAAALAHVPVAQLLDVQQQVAQEIQGAPDPAVWGERIAG----GSVLLPFAPVIDGELLSQRPAEAIAGGAGHDVDLLFGTTTDEYRLFLAPTGLLPFITGDYVTTHLAK--------SGLDADAAKAYTAEGRGEE--PGDILASIITDQVFRIPALRIAESRVDAPARTFGYEFAWRTPQLDGILGACHAVELPFVFRTLDRAA--SLVGTNPPEELAETVHNAWVRFATSGDP-----GWPAWNPETRSVMRF 473          

Query:   19 VSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQP-------ASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADA-GNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALI-----AAGEKVRGSGGNVL--DRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLFDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVPAPDESAFPSYDPANRAVYDF 488
            ++ + GI YAE P G  RF  P   R  +G  DA+ F  TA +P       A  +E  + G      +D L LNVWTP       PVMVWIHGG F  GSGS P+YDGA+ A  G VV VS NYRLG +GF       +D  DA  N GLLDQIAALEWV++NI  FGGD GNVT+FGESAGAMSV TL+A    RGLF R I QSGA + A  A  A    A +    GVE  A   A  P A +        ++++G+    +  +RI G    G  L+ F PVIDG L+S  P E+I  G G  V LL GT  DE+RLF      LP          LA +        A  A AY  E   EE  P    ++++TD  FR+PA+R+ E+R ++ A  + Y F+W +P   GILG+CHA+ELPFVF T+      S VG  PP  L+E + + W+ FA  G P      +P+++P  R+V  F
Sbjct:   20 IAVFRGIPYAEPPVGAHRFTAPRPPRPWDGVRDATEFSATAPRPPYPEAIGALLIERFIPG------DDYLTLNVWTPDPNAVGLPVMVWIHGGAFTNGSGSEPVYDGAAFARDG-VVFVSFNYRLGIIGF-------ADLPDAPSNRGLLDQIAALEWVRDNIARFGGDPGNVTVFGESAGAMSVCTLMATPRARGLFRRAILQSGAGNMAVAAEDATTIAAVIAHRLGVEPTAAALAHVPVAQLLDVQQQVAQEIQGAPDPAVWGERIAG----GSVLLPFAPVIDGELLSQRPAEAIAGGAGHDVDLLFGTTTDEYRLFLAPTGLLPFITSDYVTAHLAKSG-----LDADAAKAYTAEGRGEE--PGDILASIITDQVFRIPALRIAESRVDAPARTFGYEFAWRTPQLDGILGACHAVELPFVFRTLDRAA--SLVGTNPPEELAETVHNAWVRFATSGDP-----GWPAWNPETRSVMRF 473          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADE-WRLFDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRS--SQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTI-GATGMNSFVGDEPPVGLSERMQDTWLHFARHGVPAPDESAFPSYDPANR 483
            VTT  G   G     V ++ GI YA+ P G  RF+ P         +DA+++G    QP+  L +    +   + EDCL +NV+ P     + PVMVWIHGG F  G+GS P+YDG+ LA +G+V+VV++NYRLGP GFLHL   +  ++D  NLGLLDQ AAL+WV+ENI  FGGD  NVT+FGESAG MS+A LLA    +GLF + I +SGA    T    AA T+A  +   G+ +      LD    ++A + ++ +     D++  A +     + FQP +D   +   P ++I  G    + LL GT  DE +  F P         L   LE L    P  E+ +              ++ PRS  SQ  +MTD  F  PAV    A++   AP + Y F W  P       + HALELPFVFG + G   M      +    LS  +Q  W+ FA+ G P+ +   +P+Y    R
Sbjct:    6 VTTQYGKVKGTTENGVHKWKGIPYAKPPVGQWRFKAPEPPEVWEDVLDATAYGSICPQPSDLLSLSYT-ELPRQSEDCLYVNVFAPDTPSKNLPVMVWIHGGAFYLGAGSEPLYDGSKLAAQGEVIVVTLNYRLGPFGFLHLSSFNEAYSD--NLGLLDQAAALKWVRENISAFGGDPDNVTVFGESAGGMSIAALLAMPAAKGLFQKAIMESGASRTMTKEQ-AASTSAAFLQVLGINE----GQLDKLHTVSAEDLLKAA-----DQLRIAEKENIFQLFFQPALDPKTLPEEPEKAIAEGAASGIPLLIGTTRDEGYLFFTPDSDVHSQETLDAALEYL-LGKPLAEKVA--------------DLYPRSLESQIHMMTDLLFWRPAVAYASAQSHY-APVWMYRFDW-HPKKPPYNKAFHALELPFVFGNLDGLERMAKAEITDEVKQLSHTIQSAWITFAKTGNPSTEAVNWPAYHEETR 460          

Query:    5 TTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQ--EARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQT--TAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLFDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFV-GDEPPV--GLSERMQDTWLHFARHGVPAPDE-SAFPSY---DPANRAVYDFG 489
            TT G +   L+ G +  + G+ YAE P GDLR+R    H    G  DAS++GP+A QP       + G       DEDCL LN+WTP   G  RPV+VWIHGGG +TGSG+ P Y   + A  GD+V +SINYRLGPLGFL  G  D       N+ L DQ+ AL W+ +N+  FGGD   +T+ G+S GA S+A L      R LFHR I QS       P +V   T  T  +    G +DI  L       LI      +G+ G +++      + G   +AF PV D + I   PIESI       +   T         FDP        ++ + L++         +     A+AYE     +   P +  + ++ D  F     R+ + RA +  P   Y F   SP++ G LG+ H +E+PF F  +       FV G +P V   ++  +   W+ F R G P  D+   +P++   DPA   V D G
Sbjct:    9 TTAGDLGGCLEDG-LYVFRGVPYAEPPVGDLRWRAARPHAGWTGVRDASAYGPSAPQPVEPGGSPILGTHGDPPFDEDCLTLNLWTPNLDGGSRPVLVWIHGGGLLTGSGNLPNYATDTFARDGDLVGISINYRLGPLGFL-AGMGDE------NVWLTDQVEALRWIADNVAAFGGDPNRITLVGQSGGAYSIAALAQHPVARQLFHRAILQSPPF-GMQPHTVEESTARTKALARHLGHDDIEALRHEPWERLI------QGTIGVLMEHT----KFGEWPLAFYPVFDEATIPRHPIESIIDSDIEIIIGWTRDEGTFPFAFDPQVSQADRDQVESWLQK---------RFGDHAASAYEAHA-GDGTSPWTVIANVVGDELFHSAGYRVADERA-TRRPVRAYQFDVVSPLSDGALGAVHCIEMPFTFANLDRWTGKPFVDGLDPDVVARVTNVLHQAWIAFVRTGDPTHDQLPVWPTFRADDPAVLVVGDEG 475          

Query:    2 PEVTTTGGVAIGLDLGT----VSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPA-SALEVMLGGKQEARD-----EDCLRLNVWTPGATGAD--RPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSG-AVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLFDPSRKPLPAARLTTRLERLAAAAPS--------PEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGIL------GSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVPAP-DESAFPSYDPANRAV-YDFGT 490
            P+V T  G   G  +      +  + G+ ++  P G LRF PP       G  DA+++ P   Q +   L  M    +E        EDCL LNV+ P     D   PVMVW  GG F+ G+ SS  Y+G+ LA R  VV+V + +RLG  GFL       D    GN GLLDQ+AAL WVQENI  FGGD GNVT+FG+SAGAMS++ L+ +    GLFHR I+QSG A+      S   +   KV   AG    +    ++    ++  + +R S      +++   +    + +  PV+DG +I   P+  +  G   SV  L G N  E+    P     P  R   R E +     S         EQ    +    +   + +  + R+    ++ DA F    ++      ++  P Y Y F      A GI+      G+ H  E+ F+FG   ATG++  +G E    LS +M   W +FAR G P   +   +P Y+   + +  DF T
Sbjct:   27 PQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASS--YEGSDLAAREKVVLVFLQHRLGIFGFLS----TDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRDAGLPVYLYEFEHH---ARGIIVKPRTDGADHGDEMYFLFGGPFATGLS--MGKEK--ALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTT 532          

Query:   19 VSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGK------QEARDEDCLRLNVWTPGAT--GADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLFDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMV-----PRSSQSA---LMTDAAFRLPAVRMLEARAESDAPGYHYHF----SWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVP 468
            V  + GI +A+ P G LRF PP    S +G  D ++      Q  +A+E     +       ++  EDCL L+++TP  +  G++ PVMVWIHGG  + G  S  +YDG+ LA   +VVVV I YRLG LGF   G    D    GN G LDQ+AAL WVQ+NI  FGG+   VTIFGESAG  SV++L+ +   +GLFH  I +SG      P  +A  ++A V+    V +++    +D  AL+     +RG     +  I+   ++ P       V+DG  +   P E + S   + V  + G N +E+    P  K +        ++R A+ A   +  +  +      ++  EE +     P++ Q+    +M D+ F +PA+++   +  S AP Y Y F    SW   +    + + H  ELPFVF +        F  +E    LS +M   W +FAR+G P
Sbjct:   55 VQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTG----DKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA--LLPGLIA--SSADVISTV-VANLSACDQVDSEALVGC---LRGKSKEEILAINKPFKMIPG------VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIP--KVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQC-SRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKFTEEEE--QLSRKMMKYWANFARNGNP 500          

Query:    2 PEVTTTGGVAIGLD-------LGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQP---------------ASALEVMLGGKQEARDEDCLRLNVWTP-----GATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLF-----------DPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHF--SWASPVAGGILGSCHALELPFVFGT--IGATGMNSFVGDEPPVGLSERMQDTWLHFARHG---VPAPDESAFPSYDPANR----AVYDFGTNDELAEH 497
            P V T  G   GL        LG V +Y G+ YA  PTG+ RF+PP +  S  G  +A+ F     Q                 ++L+ ++   Q+ ++EDCL LN++ P         + +PVMV+IHGG +M G+G+  + DG+ LA  G+V+V++INYRLG LGFL  G    D A  GN GLLDQI AL W++EN+G FGGD   VTIFG  AGA  V+ L  +    GLF + I QSG   ++   +       +++      D  G   LD   ++   +       N  + I          +AF PVIDG +I   P   +  G   +  ++ G N  E   F            P+      +     L        +  +T   +   +  + + E    R +  AL TD  +  PAV   +  A+  +P Y Y F     S +      S H  E+P+VFG   IG T + S    +  V LS  +   W +FA+ G    P P ++ F    P NR    A   +   D+L  H
Sbjct:   46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQD-QNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTG----DQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL-----ADKVGCNMLDTTDMVECLK-----NKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETR--RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP-NRFEEVAWSKYNPKDQLYLH 571          

Query:    2 PEVTTTGGVAIGLDLGT-----VSRYAGIRYAEAPTGDLRFRPPV-AHRSNGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGAD----RPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHN----------------ATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVG--RSVALLTGTNADEWRLFDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSW---ASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFAR-HGVPAPDESAFPSYDPANRAVYDFGTNDEL 494
            P V+T  G   G++L T     +  + GI YA+ PTG LRF+ P  A    G   A+   P+ +Q  S L++          EDCL LN+WTP +   +    + VMVWIHGGG+ +GS +  +YDG +L+  GDVVVV++NYRL   GFL+    D+     GN+ L DQ+ AL+WV  NI  FGGD   VT+FGES GA + + L  +   +GLF +++ +SG+ +N                AT    A +T   + +   V  +A +  + PA       K  GS    ++ I   H  G +++   P     LI    + ++ +GV      AL      + +++F  S   L  A  T  +          +   A      +VE D EE + RS+   ++ D     P + + +  +E  A    Y F      S      +G+ H  E+ FVFG +       +  +E    LSE M  TW +F +   +   + S +PSY  +        TN+++
Sbjct:   30 PVVSTEAGSFQGMELTTHGERVIYAFLGIPYAKPPTGLLRFKKPQPADFIQGTYKATEKPPSCFQLDSDLQLPWADPDSPMKEDCLFLNLWTPASLSTEEEELKSVMVWIHGGGYTSGSSALDVYDGQTLSSSGDVVVVTMNYRLDAFGFLNSLTEDA----PGNMALYDQLLALQWVHTNIKYFGGDPNKVTLFGESVGAFATSFLALSPLTKGLFQKIMLESGSAYNKLTVNSIDQAKNNNQLATLVGCANETFTLISNPEEV--VACMREVAPAKFTQTYYKELGSEREKINFIFWPH-FGDDIL---PTRTAELIKEKNLTALFAGVNSVEGSALSVFFFPEVYQMFVESNLTLTKAYATILMNEFFKVFNFQDSAKAIEFYLGDVEDDDEEGI-RSALFGVVGDYIITCPTIYLADKYSERGANVQFYRFDRRPSTSQWPPEWMGAAHNDEIQFVFG-MPVRYPEKYTEEER--TLSEYMTRTWTNFVKSEDLKLKNGSQWPSYSLSEPQFATLQTNEQI 540          

Query:    2 PEVTTTGGVAIGLDLG------TVSRYAGIRYAEAPTGDLRFRPPV-AHRSNGAVDASSFGPTAWQPASA---LEVMLGGKQEA----RDEDCLRLNVWTPG--ATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAK-VMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADE--WRL-----FDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHF----SWASPVAGGILGSCHALELPFVFGT-IGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVP 468
            P V TT G  +G  +       +V+ + G+ +A+ P G LRF PP  A   +   + +++ P   Q A+    +  +L  ++E       EDCL LN++TP      +  PVMVWIHGGG   G  S+  YDG  L+   +VVVV+I YRLG  GF   G    D    GN G LDQ+AAL WVQ+NI  FGGD G+VTIFGESAG  SV+ L+ +   + LFHR I++SG V      +   +  AK + D AG E       +         E +       L ++    +   +      V+D  ++   P E +      +V  + G N  E  W L     F P+   L      T LE+ A+    PE         Y    D + +  R    A + D +F +P+V +     ++ AP Y Y +    S++SP     +   HA +L  VFG  I   G       E  + LS+ +   W +FAR+G P
Sbjct:   24 PVVDTTKGKVLGKYVSLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCSQDAAKGQRMNDLLTNRKEKIHLEFSEDCLYLNIYTPADFTKNSRLPVMVWIHGGGMTLGGAST--YDGRVLSAYENVVVVAIQYRLGIWGFFSTG----DEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVFLPGLLTKDVRPAAKQIADMAGCETTTSAIIVHCLRQKTEEELLEIMKKMNLIKLSSQRDNKESYHFLSTVVDNVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMMGFVPADVELDKKMAITLLEKFASLYGIPEDIIPVAIEKYRKGSD-DSIKIRDGILAFIGDVSFSIPSVMVSRDHRDAGAPTYMYEYQYYPSFSSPQRPKHVVGDHADDLYSVFGAPILRDG-----ASEEEIKLSKMVMKFWANFARNGNP 507          

Query:    2 PEVTTTGGVAIGLD-------LGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFG---PTAWQPASALEVMLG-----------GKQEARDEDCLRLNVWTPGA-----TGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLF-----------DPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHF--SWASPVAGGILGSCHALELPFVFGT--IGATGMNSFVGDEPPVGLSERMQDTWLHFARHG---VPAPDESAFPSYDPANR----AVYDFGTNDELAEH 497
            P V T  G   GL        LG V +Y G+ YA  PTG+ RF+PP    S  G  + + F    P      S L  ML               + ++EDCL LN++ P         + +PVMV+IHGG +M G+G+  + DG+ LA  G+V+V++INYRLG LGFL  G    D A  GN GLLDQI AL W++EN+G FGGD   VTIFG  AGA  V+ L  +    GLF + I QSG   ++   +       +++      D  G   LD   ++   E +R    N  + I          +AF PVIDG +I   P   +  G   +  ++ G N  E   F            P+      +     L        +  +T   +   +  + + E    R +  AL TD  +  PAV   +  A+  +P Y Y F     S +      S H  E+P+VFG   IG T + S    +  V LS  +   W +FA+ G    P P ++ F    P NR    A   +   D+L  H
Sbjct:   46 PVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTG----DQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL-----ADKVGCNMLDTTDMV---ECLRNK--NYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETR--RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP-NRFEEVAWSKYNPKDQLYLH 571          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSD-FADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVE--DIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRL---FDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPP-VGLSERMQDTWLHFARHGVP-APDESAFPSYDPANRAVYDFGTNDELA 495
            V T  G   G+    V  + GI YA  P G  RFRPP +  S NG  D S FGP+AWQP+  +   LG +     EDCL LN+W+PG  G  RPV+VWIHGG F++GSGSSP+YDG S A+ GD+VVV+INYRLG LGFLHL  L  D + ++GN G+LDQIAAL+WV+ENI  FGGD   VTIFGESAGAMSV  LLA+   +GLF++ I QSGA  +   +  A + T  ++   G+E  +I  L  +    LI    K+                    +M+  PVIDG ++   P E +  G  + + +L GTN DE+RL   FDP  K    A +  R           +QT          E    + + +S    LMT   F  PA+ + E +AE  +P + Y F W S    G+L SCHALE+PFV+ TI   G+ +F GD P    LS++M + W+ FA++G P   D   +P YD  NR    F TN E+ 
Sbjct:    3 VETAYGKVKGIQENDVYVWKGIPYAAPPIGPNRFRPPTSLESWNGVKDCSEFGPSAWQPSLEIMSFLGNQTTHMSEDCLTLNIWSPGTDGKKRPVLVWIHGGAFISGSGSSPLYDGTSFAKNGDLVVVTINYRLGILGFLHLAELGGDGYQNSGNCGILDQIAALKWVKENIAAFGGDPDQVTIFGESAGAMSVGVLLASPKAKGLFNQAILQSGAASHVIKSEKATKNTEFLLHELGLEKTEIQKLEEIPVEQLIEVSVKLP-------------------MMSLIPVIDGEILPKHPKELLAEGAAKDIPVLIGTNKDEYRLFTAFDPIWKKEDQAAIKKRF----------QQTFGTRWTKISQEFIKGKELTQSLYEKLMTIMTFTHPAIHVAEIQAEQGSPVWMYRFDWESQAFNGLLKSCHALEIPFVWNTISKHGVENFTGDSPDRQELSKKMHNAWIAFAQNGDPNMNDLPNWPKYDLQNRTTLIFNTNCEVV 474          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSD-FADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVE--DIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRL---FDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVG-LSERMQDTWLHFARHGVP-APDESAFPSYDPANRAVYDFGTNDELA 495
            V T  G   G+    V  + GI YA  P G  RFRPP +  S +G  D S FGP+AWQP+  +   LG +     EDCL LN+W+PG  G  RPV+VWIHGG F++GSGSSP+Y+G S A+ GD+VVV+INYRLG LGFLHL  L  D + ++GN G+LDQIAAL+WV+ENI  FGGD   VTIFGESAGAMSV  LLA+   +GLF++ I QSGA  +   +  A + T  ++   G+E  +I  L  +    LI    K+                    +M+  PVIDG ++   P E +  G  + + +L GTN DE+RL   FDP  K    A +  R           +QT          E    + + +S    LMT   F  PA+ + E +AE  +P + Y F W S    G+L SCHALE+PFV+ TI   G+ +F GD P    LS++M + W+ FA++G P   D   +P YD  NR    F TN E+ 
Sbjct:    3 VETAYGKVKGIQENDVYVWKGIPYAAPPIGPNRFRPPTSAESWDGVKDCSEFGPSAWQPSLEIMSFLGNQTTRMSEDCLTLNIWSPGTDGKKRPVLVWIHGGAFISGSGSSPLYEGTSFAKNGDLVVVTINYRLGILGFLHLAELGGDGYQNSGNCGILDQIAALKWVKENIAAFGGDPDQVTIFGESAGAMSVGVLLASPKAKGLFNQAILQSGAASHVIKSEKATKNTEFLLHELGLEKTEIQKLEEIPVEQLIEVSVKLP-------------------MMSLIPVIDGEILPKHPKELLAEGAAKDIPVLIGTNKDEYRLFTAFDPIWKKEDQAAIKKRF----------QQTFGTRWTKISQEFIKGKELTQSLYEKLMTIMTFTHPAIHVAEIQAEQGSPVWMYRFDWESQAFNGLLKSCHALEIPFVWNTISKHGVENFTGDSPDRQELSKKMHNAWIAFAQNGDPNMNDLPNWPKYDLQNRTTLIFNTNCEVV 474          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSD-FADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVE--DIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRL---FDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEP-PVGLSERMQDTWLHFARHGVP-APDESAFPSYDPANRAVYDFGTNDELA 495
            V T  G  IG+    V  + GI YA  P G  RFRPP +  S +G  D S FGP+AWQP+  +   LG +     EDCL LN+W+PG  G  RPV+VWIHGG F++GSGSSP+YDG S A+ GD+VVV+INYRLG LGFLHL  L  D + ++GN G+LDQIAAL+WV+ENI  FGGD   VTIFGESAGAMSV  LLA+   +GLF++ I QSGA  +   +  A + T  ++   G+E  +I  L  +    LI    K+                    +M+  PVIDG ++   P E +  G  + + +L GTN DE+RL   FDP  K    A +  R           +QT          E    + + +S    LMT   F  PA+ + E + E  +P + Y F W S    G+L SCHALE+PFV+ T    G+ +F GD P    LS+++ + W+ FA++G P   D   +P YD  NR    F +N E+ 
Sbjct:    3 VETAYGKVIGIQENDVYVWKGIPYAAPPIGPNRFRPPTSLESWDGVKDCSEFGPSAWQPSLEIMSFLGNQTTHMSEDCLTLNIWSPGTDGKKRPVLVWIHGGAFISGSGSSPLYDGTSFAKNGDLVVVTINYRLGILGFLHLAELGGDGYQNSGNCGILDQIAALKWVKENIAAFGGDPDQVTIFGESAGAMSVGVLLASPKAKGLFNQAILQSGAASHVIKSEKATKNTEFLLHELGLEKTEIQKLEEIPVEQLIEVSVKLP-------------------MMSLIPVIDGEILPKHPKELLAEGAAKDIPVLIGTNKDEYRLFTVFDPIWKKEDQAAIKKRF----------QQTFGTRWTKISQEFIKGKELTQSLYEKLMTIMTFTHPAIHVAEIQTEQGSPVWMYRFDWESQAFNGLLKSCHALEIPFVWNTFSKHGVENFTGDSPGRQELSKKIHNAWIAFAQNGDPNINDLPNWPKYDLQNRTTLIFNSNCEVV 474          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSD-FADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVE--DIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRL---FDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEP-PVGLSERMQDTWLHFARHGVP-APDESAFPSYDPANRAVYDFGTNDELA 495
            V T  G   G+    V  + GI YA+ P G  RFRPP +  S NG  D S FGP+AWQP+  +   LG +     EDCL LN+W+PG  G  RPV+VWIHGG F++GSGSSP+YDG S A+ GD+VVV+INYRLG LGFLHL  L  D + ++GN G+LDQIAAL+WV+ENI  FGGD   VTIFGESAGAMSV  LLA+   +GLF++ I QSGA  +   +  A + T  ++   G+E  +I  L  +    LI    K+                    +M+  PVIDG ++   P E +  G  + + +L GTN DE+RL   FDP  K    A +  R           +QT          E    + + +S    LMT   F  PA+ + E + E  +P + Y F W S    G+L SCHALE+PFV+ T    G+ +F GD P    LS+++ + W+ FA++G P   D   +P YD  NR    F +N E+ 
Sbjct:    3 VETAYGKVKGIQENDVYVWKGIPYADPPIGPNRFRPPTSLESWNGVKDCSEFGPSAWQPSLEIMSFLGNQTTHMSEDCLTLNIWSPGTDGKKRPVLVWIHGGAFISGSGSSPLYDGTSFAKNGDLVVVTINYRLGILGFLHLAELGGDGYQNSGNCGILDQIAALKWVKENIAAFGGDPDQVTIFGESAGAMSVGVLLASPKAKGLFNQAILQSGAASHVIKSEKATKNTEFLLHELGLEKTEIQKLEEIPVEQLIEVSVKLP-------------------MMSLIPVIDGEILPKHPKELLAEGAAKDIPVLIGTNKDEYRLFTVFDPIWKKEDQAAIKKRF----------QQTFGTRWTKISQEFIKGKELTQSLYEKLMTIMTFTHPAIHVAEIQTELGSPVWMYRFDWESQAFNGLLKSCHALEIPFVWNTFSKHGVENFTGDSPGRQELSKKIHNAWIAFAQNGDPNINDLPNWPKYDLQNRTTLIFNSNCEVV 474          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSD-FADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVE--DIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRL---FDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEP-PVGLSERMQDTWLHFARHGVP-APDESAFPSYDPANRAVYDFGTNDELA 495
            V T  G   G+    V  + GI YA  P G  RFRPP +  S +G  D S FGP+AWQP+  +   LG +     EDCL LN+W+PG  G  RPV+VWIHGG F++GSGSSP+Y+G S A+ GD+VVV+INYRLG LGFLHL  L  D + ++GN G+LDQIAAL+WV+ENI  FGGD   VTIFGESAGAMSV  LLA+   +GLF++ I QSGA  +   +  A + T  ++   G+E  +I  L  +    LI    K+                    +M+  PVIDG ++   P E +  G  + + +L GTN DE+RL   FDP  K    A +  R           +QT          E    + + +S    LMT   F  PA+ + E + E  +P + Y F W S    G+L SCHALE+PFV+ T    G+ +F GD P    LS+++ + W+ FA++G P   D   +P YD  NR    F +N E+ 
Sbjct:    3 VETAYGKVKGIQENDVYVWKGIPYAAPPIGPNRFRPPTSAESWDGVKDCSEFGPSAWQPSLEIMSFLGNQTTRMSEDCLTLNIWSPGTDGKKRPVLVWIHGGAFISGSGSSPLYEGTSFAKNGDLVVVTINYRLGILGFLHLAELGGDGYQNSGNCGILDQIAALKWVKENIAAFGGDPDQVTIFGESAGAMSVGVLLASPKAKGLFNQAILQSGAASHVIKSEKATKNTEFLLHELGLEKTEIQKLEEIPVEQLIEVSVKLP-------------------MMSLIPVIDGEILPKHPKELLAEGAAKDIPVLIGTNKDEYRLFTAFDPIWKKEDQAAIKKRF----------QQTFGTRWTKISQEFIKGKELTQSLYEKLMTIMTFTHPAIHVAEIQTEQGSPVWMYRFDWESQAFNGLLKSCHALEIPFVWNTFSKHGVENFTGDSPGRQELSKKIHNAWIAFAQNGDPNINDLPNWPKYDLQNRTTLIFNSNCEVV 474          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFR-PPVAHRSNGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHL-DSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVE--DIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRL---FDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGL-SERMQDTWLHFARHGVPAPDE-SAFPSYDPANRAVYDFG 489
            V +  G   G  +  V  + GI YA+ P G LRFR P + +   G  DA+SF P A QP S +   LG +    DEDCL LNVW+PGA    RPVMVWIHGG F++GSGSS  YDGAS A +GDVVVV+INYRLG LGFLHLG +   ++A++GN G+LDQ+AAL WV+ENI  FGGD  NVT+FGESAGAMS+  LL     +GLFH+ I QSGA  N  P+  A +  +K++ A  V+  +I+ L  L                   +D++  A  L P +M+  PVIDG  I  AP E+I +G  + V++L GTN DE+R+   FDP  K    +++T+  E+          T   L      +    + + +   + L+T + F  PA R+ E +    AP + Y F W +PV GG L + HALE+PFV+ T+      +F G  P   L + +M   W+ FAR+G P  ++ S +P YD   R    F 
Sbjct:    6 VESIYGKLQGEKIDGVFAWKGIPYAKPPVGALRFRAPELPNSWEGVRDATSFSPVAPQPQSEIMEFLGNETLNMDEDCLYLNVWSPGADDKKRPVMVWIHGGAFISGSGSSHWYDGASFAAQGDVVVVTINYRLGILGFLHLGEIGGEEYANSGNCGILDQVAALHWVRENISAFGGDPNNVTVFGESAGAMSIGILLGFPFAQGLFHKAILQSGAAANVHPSGKATKIASKLLAALDVDPTNISKLEELP------------------VDQLVQASTLVP-MMSLGPVIDGVSIPKAPEEAISAGSAKDVSILIGTNKDEYRIFTAFDPEWKNADESKVTSHFEK----------TFGPLLPIISRQFSDGKPLNQELFNKLLTISIFTSPAQRLAELQVNHGAPVWMYRFDWETPVFGGALKATHALEIPFVWNTLNKPKTENFTGASPERQLVANQMHSAWISFARNGNPNTEQNSEWPKYDVEKRQTMIFN 471          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRSNGAV-DASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHL-DSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVE--DIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRL---FDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPP-VGLSERMQDTWLHFARHGVPAPD-ESAFPSYDPANRAVYDFGTNDELA 495
            + +  G   G  LG V  + GI +A+ P G LRFR P    S G V DA+SFGP A Q    +   LG      +EDCL LNVW+PGA    RPVMVWIHGG F++GSGSS  YDGAS AE+GDVVVV+INYRLG LGFLHL  +  +++A +GN G+LDQ+AAL+WVQ+NI  FGGD  NVT+FGESAGAMS+  LL     +GLF + I QSGA  N  PA  A +   +++ A  VE  ++A L  +    LI A +                  L P  M+  PV+DG  +   P E+I++G  ++V++L GTN DE+ +   FDP  K     ++T+  E+          T   L         +   + +   + L+T + F  PA+++ E +    AP + Y F W +PV GG L + HALE+PFV+  +      +F G  P   G++++M  TW++F  +G P+ D  + +P+YD   R+   F T  ++ 
Sbjct:    3 IKSAYGKLQGEQLGEVFAWKGIPFAKPPVGPLRFRAPELPDSWGGVRDATSFGPVAPQTQREIMEFLGNDISNMNEDCLYLNVWSPGADDKKRPVMVWIHGGAFVSGSGSSSWYDGASFAEQGDVVVVTINYRLGILGFLHLAEIGGAEYATSGNCGILDQVAALQWVQDNIAAFGGDPNNVTVFGESAGAMSIGVLLGLPSAQGLFQKAILQSGAAANVHPAERATKVAGQLLTALQVEPSNLAKLEEMPVEQLIQASDL-----------------LPP--MSLSPVVDGVSLPIPPEEAIKNGSAKNVSILIGTNKDEYNIFSVFDPEWKDADDTKVTSLFEK----------TFGPLVPLIRSYFSSNAPLSQELYNKLLTMSIFTGPALKLTELQVNQGAPVWMYRFDWETPVFGGKLKATHALEIPFVWNNLDKENTTNFTGSSPERQGVADQMHQTWINFVHNGNPSTDGLTDWPAYDVNKRSTMIFNTESKMV 474          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGAD-RPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHL-DSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVED--IAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLF---DPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEP-PVGLSERMQDTWLHFARHGVP----APDESAFPSYDPANRAVYDFGTNDEL 494
            V TT G   G     V  + GI YA+AP G LRF+PP A  S +G +DA+ FGP A QP S +   LG       EDCL LN+W+P       RPVMVWIHGG +M GSGSS +Y+G S A  GDVVVV+INYRLG LGFLHLG L   ++A +GN G+LDQ+AAL+WVQ+NI  FGGD   VTIFGESAGAMSV  LLA    +GLF++ I QSGA  N  P+S A +   +++ + G+ED  +  L  +    LI     +                    +M   PV+DG  +   P E+++ G  + + ++ G N DE+RLF   DP  K      +    E     A            A + ++   + + +     LMT   F  PA+++ E +    AP Y Y F W SPVAGG L +CHALE+PFV+  +     N   G+ P   G++++M   W+ FA  G P     PD   +P Y+   R    F    ++
Sbjct:    7 VNTTYGQVKGEKNENVYVWKGIPYAKAPVGSLRFQPPEAPESWDGVLDATQFGPVAPQPESEIMETLGNDSVNSSEDCLNLNIWSPSINKDKLRPVMVWIHGGAYMNGSGSSGLYNGTSFASLGDVVVVTINYRLGILGFLHLGELAGEEYATSGNCGILDQVAALQWVQDNIASFGGDPNRVTIFGESAGAMSVGVLLAMPSAKGLFNQAILQSGAASNTIPSSQATKVAERILTSLGIEDNEVFKLRDIPVEKLIEVSSTLP-------------------MMKLVPVVDGVSLPNNPEEALKDGFAKDIPIIIGVNKDEYRLFTYFDPRWKNAEQREVEQIFESTFGTA----------MPAIQSQLSENDTLDQDLYDKLMTAQIFTNPALKLAEYQVRQGAPTYMYRFDWESPVAGGALKACHALEIPFVWNNLNEPQTNQLTGNSPEQKGIAKQMHQAWIAFAHSGNPNHEGIPD---WPEYNLTKRETMLFNEESKV 478          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRS-NGAVDASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRP-------VMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSDFADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVEDIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLFDPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDEPPVGLSERMQDTWLHFARHGVP-APDESAFPSYDPANRAV 485
            V+T  G   G+    ++R++G+ +A+ P G+LRFRPPVA     G  DA+ FGP + Q  S ++ + GG+ E   EDCL LNVWTP     D+P       VMVWIHGGGF  GSGSSP+Y G S A  G VV+V++NYRLG LGFL LG++D  +A +GNLGLLDQ+AAL+WVQ+NI  FGGDA NVTIFGESAGAMSV+TLL     +GLFH+ IAQSGA   +     A+  TA+ +  AG+  I  L       L+AA   +  +       I   H      + F+PV DG  + A P+ +++ G    + LL GTN +EW+LF  +    PA      L R    + +P Q       AY  E     +     + A++TD  FR+PA R+  A+A + AP + Y F W SP   G++G+ HA+E+PFVF  +    ++  VG E P  L+  M   W+ FAR GVP AP    +P  D + R V
Sbjct:   12 VSTAQGALRGVWNDQIARFSGVPFAQPPIGELRFRPPVAAEPWEGERDATGFGPVSAQNPSLMDSLFGGESEEWSEDCLYLNVWTPQLPIQDQPASGSGLAVMVWIHGGGFEMGSGSSPLYHGESFARDG-VVLVTLNYRLGALGFLELGNMDPAYAGSGNLGLLDQVAALQWVQQNISQFGGDASNVTIFGESAGAMSVSTLLTMPRAKGLFHKAIAQSGAASASRSPEQASVDTAEFLGLAGLSTIEQLKEASVQELLAAHAAMGAARMADPQGIVEKHRSPLAFLPFRPVTDGQEVPADPLGAVQEGTAAGIPLLIGTNLEEWKLF--ALMTPPATTEEGLLARFGLVSENPAQA----LEAYRSEHPGASLA--DLEGAVLTDFVFRIPATRLAHAQA-AHAPVWQYRFDWRSPAWNGMIGAAHAVEIPFVFDLVHDHRLHVLVGPEAPAELASAMHLAWIEFARAGVPAAPQLPDWPLADVSGRPV 492          

Query:    4 VTTTGGVAIGLDLGTVSRYAGIRYAEAPTGDLRFRPPVAHRSNGAV-DASSFGPTAWQPASALEVMLGGKQEARDEDCLRLNVWTPGATGADRPVMVWIHGGGFMTGSGSSPIYDGASLAERGDVVVVSINYRLGPLGFLHLGHLDSD-FADAGNLGLLDQIAALEWVQENIGGFGGDAGNVTIFGESAGAMSVATLLAAAGDRGLFHRVIAQSGAVHNATPASVAAQTTAKVMDAAGVE--DIAGLAALDPAALIAAGEKVRGSGGNVLDRIDGAHELGPNLMAFQPVIDGSLISAAPIESIRSGVGRSVALLTGTNADEWRLF---DPSRKPLPAARLTTRLERLAAAAPSPEQTSAALAAAYEVEVDAEEMVPRSSQSALMTDAAFRLPAVRMLEARAESDAPGYHYHFSWASPVAGGILGSCHALELPFVFGTIGATGMNSFVGDE--PPVGLSERMQDTWLHFARHGVP-APDESAFPSYDPANRAVYDFGTNDELA 495
            V T  G  +G   G +  + GI YA+ P G LRFR P    + G V DA+ F P A Q  S +   LG + E  +EDCL LN+WTPGA    RPVMVW+HGG F  GSGSS +YDG S A  GDVVVV+ NYRLG  GFLH+G    D F  +GN G+LDQ+A L+WV++NI  FGGD   VT+FGESAGAMS+  LLA+   +GLFH+ I QSGA  N    S A + T + ++   +E  ++  L  +    LI     +                     M+  PVIDG  +   P + +  G    +++L GTN DE+RLF   DP  +      +T+  E          QT  +       +    E + ++    L+T   FRLPA+R+ E + +  AP + Y F W S V  G L SCHALE+PF + T    GM  F G++      L+  M   W++FA +G P  PD   +P+YD  NR+V  F   + LA
Sbjct:    6 VETAYGKVMGEQNGEICVWKGIPYAKPPVGSLRFRAPKTPFAWGDVRDATKFSPVALQTPSEVMKFLGSELEETNEDCLYLNIWTPGADNKLRPVMVWVHGGAFAAGSGSSSMYDGTSFASEGDVVVVTFNYRLGVFGFLHVGDAGGDEFVGSGNCGILDQVATLQWVKDNIANFGGDPNRVTVFGESAGAMSIGVLLASPSAKGLFHQAILQSGAAANVHSTSKAEKVTNRFLELLDIEPGNLNKLKEIPAEQLIKKAASLP-------------------YMSLVPVIDGVTLLQHPEQVLAEGGANDISILIGTNKDEYRLFSYFDPRWEKGDEKEITSIFE----------QTFGSSWEGISQKFPKGEKLTQTMYDELLTMKVFRLPAIRLAEHQVKQKAPVWMYRFDWESTVFEGKLKSCHALEIPFFWNTNEKPGMEKFTGEDTSEKRNLARNMHQAWINFAHNGNPNTPDLPEWPAYDLENRSVLLFNNENSLA 478