endoribonuclease dcr-1, snap_masked-scaffold117_size339417-processed-gene-2.5 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of endoribonuclease dcr-1 vs. L. salmonis genes
Match: EMLSAG00000004598 (supercontig:LSalAtl2s:LSalAtl2s23:370173:379428:1 gene:EMLSAG00000004598 transcript:EMLSAT00000004598 description:"maker-LSalAtl2s23-augustus-gene-3.18") HSP 1 Score: 1260.36 bits (3260), Expect = 0.000e+0 Identity = 692/1291 (53.60%), Postives = 863/1291 (66.85%), Query Frame = 0
Query: 702 RAGPRKQRHYYYKTASKYLK---LEPVAPKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLT--SELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAES----GPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITEI---------FDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLKQKSLEIGTWSNEMAAPDDPPPNEADN----------EMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATG--KDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDD----------------SDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHPWVWEDTGQSEIMAGNPERATTNLKMFAVDKPLDFQINNPQSTPEDLSGPQEPGPVN------DPELASRLSAK-VKEKLLVLPTSTEKPPNTPVVKP-------GVIPRDSDRPFGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLP--DVSKLGTEEEILSMI--KDLTSDRPEQSNNKP-EDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNKSVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKRSN 1927
R G K+R YYYK + LK +P +Y L + L CPIPDDQNTRGRK++ PE + Q FGFL +P CPFPIYTRSGEVLV++ K+ + L EE+ + FH YTFS VLRLEKYPM F + + LI+P+ K E G IDWDFLR++ +E ++ K + E+ + FD+ + DAV+MPWYRNQDQPQYFYVAEI +HL+P SDFPGQGFE+F KYY++KY+ITI + +QPLLDVDHTS RLNFLTPRYV RKG++LPTSSEETKRNKRENLEQKQILVPELC IHPF SLWRQ V+LPCI YR+N LL AD LR IA E GK LD F W P++FGWTL DVLK R D+ A + + KK N T + I ++++ +++ +D+ G D+L +L+DR++N + EED K KQ+ LEIGTWSN++ + + + DEE L ++ DP ALPDNLT LSNE+LP G KDWGTGIEQ+ FRVGSPTFF NPNINIPG+MDD + S D + VT+ DG+ +IEFRG NMAEAIED EE R E L + EE +++ PW E ++E + E + +M +++ L+ + + T P++ V DPE + + K V E + P+ P GV+PRDSD FSFD+QP+L + PGPSPS+ILQ LTMSN+NDAINLERLETIGDSFLKYAI S LF Y EGRLSHLRSKQVSN +L+ LG +K +GECMI TKFEPHDNWLPP Y+V LE+ALIESG+P+ WN A LP D ++ T+E I+ +I K T+ +P +S+ + +DM SFVPYNLLTQ SIPDKSIADCVEALIGAYLI+ G++GAL FM WLG+ V P + E + S + ER L+ L G+E+FE +IGY F+DK+YLLQ+F+H S+YPNR+TDCYQRL FLGDA+LD+LITRHLYEDP++HSPGALTDLRSALVNNTIFA +AVKF FHK+ H SPGLQT+ RFVK+Q Q F+ D+FYL+ E S ED+EVPKALGD+FESVAGA+FLDSGLSLD VW I++RMM +I++F SN+PKSPIRELLELEPETAKF +PE+L+DG+RVRVSV+VFGKGTFKG+GRNYRIAKCTAAKCALRA++K S+
Sbjct: 822 RPGTTKRRQYYYKKVAGCLKPKNNDPSPISFRLYHLNMELSCPIPDDQNTRGRKIYPPENSVQGFGFLVRGGNSIPPICPFPIYTRSGEVLVEIKEKKDSILLTEEEYELIICFHRYTFSKVLRLEKYPMQFTPDKSRNSILILPMVKSTEQESELGFIIDWDFLRRIKEE---NEKKMSVVSDEDRTDYTFDKEDYLDAVIMPWYRNQDQPQYFYVAEICEHLNPTSDFPGQGFETFSKYYQTKYNITIQNLEQPLLDVDHTSHRLNFLTPRYVNRKGVALPTSSEETKRNKRENLEQKQILVPELCQIHPFPXSLWRQTVSLPCILYRINGLLIADDLRSLIAREMSFGKPELDSDFVWPPLNFGWTLADVLKNR---DNALALNTQDNPKKNRRIVNST-THVIITEALSPVSDTPAIEEIFDDEEDEGGSSKGDGDDLTRLSDRIMNKMNEEDNKRKQRQLEIGTWSNDLIENVGKQSKSIRSSSIGGKFLRFQDEFDEEDL-ELLDPNMALPDNLTLLSNELLPKTLETEGGSKDWGTGIEQKIFRVGSPTFFSNPNINIPGMMDDLDGLSCSDSDDDEDFYENFDSYRRKALDFNNPNSSVTQ-DGSVRIEFRGENMAEAIEDEHEENLRVESLARNLEEEAKMLSEVPWPEEQNEEAEDEEKDIEDQKSENEMDSIE--LEVIVLKEKDTFNRYGFPEKQSCVEYQKLEYDPEKNAVMDEKEVVETFMKDFNINNMDIMVPIDYPKDECEFTGVLPRDSDEEMSFSFDHQPELVSHPGPSPSIILQGLTMSNSNDAINLERLETIGDSFLKYAIXSYLFNVYDTVHEGRLSHLRSKQVSNLNLFKLGRKKKLGECMIATKFEPHDNWLPPSYHVQPELEQALIESGVPANLWNMAELPSTDFGRMTTKE-IVELIQEKSRTAQQPGKSSTESVQDMPSFVPYNLLTQHSIPDKSIADCVEALIGAYLISCGQRGALLFMTWLGLKVIPPEKNEGRSISSSQKVEHLPHIERQLNFFLSGYEEFEELIGYKFKDKTYLLQSFSHASFYPNRITDCYQRLXFLGDAILDYLITRHLYEDPRQHSPGALTDLRSALVNNTIFAFLAVKFQFHKYFKHFSPGLQTVIDRFVKLQVQNEFKVFDEFYLIEEDDDSEEA------------EDIEVPKALGDIFESVAGAIFLDSGLSLDAVWCIYFRMMQTEIEQFSSNVPKSPIRELLELEPETAKFGKPEKLADGKRVRVSVEVFGKGTFKGIGRNYRIAKCTAAKCALRALKKSSH 2088 HSP 2 Score: 308.531 bits (789), Expect = 1.141e-84 Identity = 184/522 (35.25%), Postives = 289/522 (55.36%), Query Frame = 0
Query: 163 HARVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSHVGSDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAASSDLFPGQAVTQSEILKTKSV---ELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHT-SVEGSGHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKD 680
++R++TLTA + LG ++ LE+ + R+E E L+ LR + P+ ++ F Q EP +E+ + + FL HR +LEETYGE+F D++++IPDP+ +P++L+ D+ +++R GVW AERAA+L+ IK+DKLKT EKYER +LLLS ++TEML++ +IC A +++++K+T Y KPK+ RL+ +LLQYKP H+ +D ++D PK+ ++S S E+ P + +D+ L + +++E+ LR+FR++E N+L+S+ LE+G+D VRCNLV+ FD+ P+S + H K+KAK S F+ L + + L L ++EK L+ R Y+ + K++ L + LNRYC+KLPSDTFTRL+P+ EG G++ GI LPIN P+K I+G +MPN T AK++AA L++ ELD + P GKD
Sbjct: 10 NSRIITLTAFLFNGDKTLGSLDKRLSKLENTFGNRIETSCEVLTTLRYVSKPRFGVLTFIQSKEPN----EVESQIENSIQGFINFLKNHRFSLEETYGEDFEDIIQEIPDPSKLPLKLIDDFLNILRTCGVWCAERAALLLTIKIDKLKTREKYERHYLLLSVLYTEMLKICKICDDAFADLTDREKMTKYSKPKLLRLMSVLLQYKPEHI-TDHSED------PKEKESKDES----------------------------------STKEEEKKVNAPPPEEEAEETDEGL------LNHRKQEEGLRRFRMRECNILISNSLLEVGIDGVRCNLVLAFDA-PDSFHTYAHYKVKAKSSVSWFLSLCQEDKLESYLNSLKEYHSIEKSLVDRCQYKDPSVEERYLSDANDHIITPFIPKNLYYPTCYLKNSILLLNRYCAKLPSDTFTRLTPLAGILKTEGGGYICGIQLPINCPLKKIIIGLVMPNETLAKRAAAYAAILELHKIGELDPFMNPVGKD 479
BLAST of endoribonuclease dcr-1 vs. L. salmonis genes
Match: EMLSAG00000005702 (supercontig:LSalAtl2s:LSalAtl2s309:326623:333557:-1 gene:EMLSAG00000005702 transcript:EMLSAT00000005702 description:"maker-LSalAtl2s309-snap-gene-3.42") HSP 1 Score: 245.743 bits (626), Expect = 1.563e-65 Identity = 183/582 (31.44%), Postives = 285/582 (48.97%), Query Frame = 0
Query: 1406 DSDRPFGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLG---WEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKL-------GTEEEILSMIKD-LTSDRPE----------------------QSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAW-LGMDVDP-------MQNEEEIQVVSPLN-------------KSVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQ-KNFEFED------DFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFK--GVGRNYRIAKCTAAKCALRAIRK 1924
+ D F F D D T L ++LT++NA + +LER E +GD+FLK + L+ A EG LS RS+ V N +L +G + +G + K +P NW P Y K LE+ +++ + + L K G LS +K+ L D P +S + +R FVP N DKSIAD +E++IG YL+ G + L MA +G+ + P + +++V LN K VV+ + L ++ E IIGY F++K++LLQAFTH+S+ N++TD Y+RLEFLGDA+LD+L+T +++ + + PG +TD RSA+VNN AI+ +K + LLH P + + +I S N EF++ DF+ + + S + +E+V+VPK LGD+ ESV GAVFLDSG L VW +F R+ P++ + ++ PK+ + +L EL PE F +++ + VS+ + +K G+G +IAK +A KC +R + K
Sbjct: 1063 NKDLSFDFLTDLNSDAQTLSFNHFEL-FKSLTLTNAGEEFDLERNEILGDAFLKIMTSIYLYFAINSKDEGYLSLYRSRIVGNRNLLRVGEMIGDLQLGGVLNAVKLQPKLNWQVPFYNNLKSLEEEIVKM---NRDFRKTVLTSNEKFKSHNFLDGMNNSDLSRLKEILCCDNPNTSIFYNDIVNKLSEARGNTNYSESKAQLSSLRVFVPVN--------DKSIADALESIIGVYLLHYGCKATLRMMATKMGISLFPNVKVENNICGHSKLKVSQSLNWFVPPTNAIQDFGKKVVNHEILNRLLLKLQYKTIEKIIGYEFKEKTFLLQAFTHSSFSSNKITDSYERLEFLGDAILDYLVTSYIFIEFPTYGPGKVTDARSAVVNNVTLAILTIKSELYCHLLHSEPLILS------RIDSMIANMEFDESNMNEFDFFKLKMSLLS--------ETECPILEEVDVPKVLGDICESVLGAVFLDSGFDLKIVWNVFKRLC-PNLDQIVALKPKNYVTKLYELFPERISFGPSKKVGNKIEKTVSLRMKDDKVYKARGIGPKGKIAKISACKCLIRGLVK 1617 HSP 2 Score: 150.984 bits (380), Expect = 1.339e-36 Identity = 184/802 (22.94%), Postives = 340/802 (42.39%), Query Frame = 0
Query: 282 VRDYQSVVRDLGVWAAERAAILM---AIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGV--SEQDKLTHYVKPKMTRLVEILLQYKPSHVGSDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS--SDLFPGQAVTQSEIL--------KTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSP-------------IFHTSVEGSGHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLKLEPV--APKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGF-LTSEL--LPASCPFPIYTRSGEVLVKVILLKEDLE---LDEE--QRNQVKEFHHYTFSDVLRLEKYPMAFNLGR----CEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAK 1041
+ D + LG++AA M KL+ EKY QF LL V+ + I + S+ K+ +++ K+ +L+EI ++ VTD S Q+ +V++K + K ++ LK++ R ++SF+ P Y++G + ++ +P K+ +D + FR N+++S+ LE G+D +CNLV+ FD + ++ + ++ K +A+ S++VI+ + +L +E+ I+ P +D + E KT S +S + L++Y + + +D FT L+P I + +E ++ + LP +P+ P+ G++ + AK+SAAL+ C +L++ ELD+ L P K + L ++ G ++ R YY + L P+ A K +Y +++ L N + L+ P+ E+ G L S L + S +Y+RSG V V ++L + L E+ N ++++ +SDVL++ M + C + LIVPL +ID DF+ K + +P ++ + VV ++ PQ ++V E+ L+P S +F +YY KY + I+D QPL+ + + A R+ + + ++ TK + + + +PEL H +S W+ + LP I R+N + N+ L + S K
Sbjct: 331 LNDISMLYNTLGMFAARIYVYTMLQDTFPEIKLRCDEKY--QFKLLQIVYDTFKSVEGIFQRKWNDFVGSDLQKMYYFMSSKLKKLLEIFTEF--------VTD---------------------SQFSMQSFTAVVFVKRRESCKIIYEVLKEILRLDSRFSFISPAYIIGQSM----VELNPGSNEMKKMQDTITNFRSGRYNLIVSTSVLEEGMDIKKCNLVIRFDEI-DTYRSYVQSKGRARAKPSMYVIMCSTTDLPTMDMKLSSFRKIEQMSITECHTLPFELQKLNDFHEENEDNEEEEDPYFVNPNDKTNSAMISPATSISLLHQYINSITTDKFTTLAPYWEYSRTTSKPHNILLSVLEEPKYVCQVTLPHKTPLNFPVKGALRASRKKAKRSAALQACTMLHQLGELDDKLIPKKKR--IHEELEELDDGLDDDEDHAKPGTKRFRRYYAQ-KKPLLSSSPILCASKVFIYTIDMHLVSITK--HNPKRYSLYYPQETERKLGLCLISPLSDIVMSNKITLYSRSGIVEVNILLANSHISGSTLVEKCGGLNTLQKYTKLIYSDVLQVVTPWMEELTEKELLECR-DPLIVPL-----LNGEIDKDFILKTIS----GQP--------------YNDGDMTERVVSLLHK--PDPQRYFVEEVIPELTPLSLINENT--TFVEYYSQKYGMKITDKSQPLIRLSNADAE------RFAYSEVVIEEKDNKLTKLGNLDFYRTRWLAIPELVLAHSVPSSFWKDLKLLPYILERINQIQNSMTLLKELCSFEK 1057
BLAST of endoribonuclease dcr-1 vs. L. salmonis genes
Match: EMLSAG00000005873 (supercontig:LSalAtl2s:LSalAtl2s3186:5073:7294:-1 gene:EMLSAG00000005873 transcript:EMLSAT00000005873 description:"snap-LSalAtl2s3186-processed-gene-0.17") HSP 1 Score: 98.2117 bits (243), Expect = 1.892e-24 Identity = 50/73 (68.49%), Postives = 54/73 (73.97%), Query Frame = 0
Query: 1411 FGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRS 1483
FD+QP+L + PS S+ILQ LTM N DAINLERLETIGDSFLKYAITS LF Y T EGRLSHLRS
Sbjct: 29 MSLCFDHQPELVSHTDPSLSIILQGLTMPNCIDAINLERLETIGDSFLKYAITSYLFNVYDTTHEGRLSHLRS 101
BLAST of endoribonuclease dcr-1 vs. L. salmonis genes
Match: EMLSAG00000005872 (supercontig:LSalAtl2s:LSalAtl2s3186:807:5015:-1 gene:EMLSAG00000005872 transcript:EMLSAT00000005872 description:"maker-LSalAtl2s3186-snap-gene-0.10") HSP 1 Score: 93.5893 bits (231), Expect = 3.035e-21 Identity = 54/119 (45.38%), Postives = 73/119 (61.34%), Query Frame = 0
Query: 1578 DMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNK-SVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLT 1695
+M SFVPYNLLTQ SIPD SIAD VEALI AYLI+ G+ + P Q + E + S L K + +R L L +E+FE +IG+ F+DK+YLLQ+++H +Y N +T
Sbjct: 22 NMPSFVPYNLLTQHSIPDNSIADSVEALIEAYLISCGQ-------------LIP-QKKNEGRSNSALQKVKHLPHIQRQLKFFLTEYEEFEELIGFKFKDKTYLLQSYSHAFFYTNHIT 126
BLAST of endoribonuclease dcr-1 vs. L. salmonis genes
Match: EMLSAG00000004435 (supercontig:LSalAtl2s:LSalAtl2s231:33920:44938:1 gene:EMLSAG00000004435 transcript:EMLSAT00000004435 description:"maker-LSalAtl2s231-augustus-gene-0.30") HSP 1 Score: 66.2402 bits (160), Expect = 8.961e-11 Identity = 51/164 (31.10%), Postives = 80/164 (48.78%), Query Frame = 0
Query: 1597 SIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNKSVVSEPERHLSH-----LLQGFEQFEHIIGYSFRDKSYLLQAFTHTSY-YPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKF 1754
++++C EA++G+ + GG A A + E I++ P + + EPE S LLQ +FE + G F L +AFT S + N QRLEFLGD VL + + +LY+ +H G L+ LRS++VNN +++ G +F
Sbjct: 837 AMSNCFEAVMGSIFLDGGIDVADRVFADALFGGENFLLETWIKI--PPHPLQIQEPEGDRSWIEKYPLLQKLTRFEDMTGIIFTHIRLLARAFTDRSIGFSNLTLGSNQRLEFLGDTVLQLITSDYLYKYFPEHHEGHLSLLRSSIVNNRTQSVVCDDLGIPRF 998
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|51316117|sp|Q9VCU9.1|DCR1_DROME (RecName: Full=Endoribonuclease Dcr-1; Short=Protein dicer-1) HSP 1 Score: 652.129 bits (1681), Expect = 0.000e+0 Identity = 336/574 (58.54%), Postives = 405/574 (70.56%), Query Frame = 0
Query: 1390 EKPPNTPVVKPGVIPRDSDRPFGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLGTEEEILSMIKD------------LTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQ------------------NEEEIQVV--------SPLNKSVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKR 1925
E P +T + ++P GFSFD QPDL PGPSPS+ILQALTMSNAND INLERLETIGDSFLKYAIT+ L++ Y + EG+LSHLRSKQV+N +LY LG K +GE MI TKFEPHDNWLPP YYVPK LEKALIE+ IP+ W A L D+ L + +I M+++ + + + SN+ D F+PYNL++Q SIPDKSIADCVEALIGAYLI G +GAL FMAWLG+ V P+ N E + V SPL + E L LL GFE+FE +GY FRD+SYLLQA TH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYEDP++HSPGALTDLRSALVNNTIFA +AV+ GFHKF HLSPGL + RFV+IQ +++ + + E LS +D EDVEVPKALGDVFES+AGA+FLDS +SLD VW ++ MM P+I++F +++PKSPIRELLELEPETAKF +PE+L+DGRRVRV+VDVF KGTF+G+GRNYRIAKCTAAKCALR ++K+
Sbjct: 1690 EPPTSTKAITSAILPA------GFSFDRQPDLVGHPGPSPSIILQALTMSNANDGINLERLETIGDSFLKYAITTYLYITYENVHEGKLSHLRSKQVANLNLYRLGRRKRLGEYMIATKFEPHDNWLPPCYYVPKELEKALIEAKIPTHHWKLADLLDIKNLSS-VQICEMVREKADALGLEQNGGAQNGQLDDSNDSCNDFSCFIPYNLVSQHSIPDKSIADCVEALIGAYLIECGPRGALLFMAWLGVRVLPITRQLDGGNQEQRIPGSTKPNAENVVTVYGAWPTPRSPLLHFAPNATEE-LDQLLSGFEEFEESLGYKFRDRSYLLQAMTHASYTPNRLTDCYQRLEFLGDAVLDYLITRHLYEDPRQHSPGALTDLRSALVNNTIFASLAVRHGFHKFFRHLSPGLNDVIDRFVRIQ-------QENGHCISEEYYLLSEEECDD------AEDVEVPKALGDVFESIAGAIFLDSNMSLDVVWHVYSNMMSPEIEQFSNSVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFCKGTFRGIGRNYRIAKCTAAKCALRQLKKQ 2242 HSP 2 Score: 477.633 bits (1228), Expect = 1.642e-136 Identity = 307/749 (40.99%), Postives = 421/749 (56.21%), Query Frame = 0
Query: 580 ILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHTSVEGSGHLS----GILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPN-----LGPLTPASAQGS---RAGPRKQRHYYYK-TASKYLKLEPVAPK-CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGK-VILDPRFQWEPMDFGWTLNDVL-KTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITEIFDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLKQKS--LEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKT----ATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDDSDGLSCSDSDDDMEDDRHFVTEEDGT-----------SKIEFRGNNMAEAIEDAAEEIKRREIL 1295
+L SV+L + +N+YC++LPSDTFT+L+ ++ + ++ + LPINSP+K I+G MP T A++ AAL+ C L+ ELD+ L P GK+ + ++P+ L P Q S R G K+R YYYK AS++ PVA C++Y ++L LQCPIP++QNTRGRK++ PE A+Q FG LT++ +P F I+TRSGEV V + L KE + L EQ + F +YTF++VLRL+K+ M F+ E IVP K G IDW FL + + P+ EE + FD FQDAVVMPWYRNQDQPQYFYVAEI HLSP S FPG + +F+ YY KY +TI + QPLLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILVPELC +HPF ASLWR V LPCI YR+N LL AD +R +++++ +G+ I D F+W +DFGW+L++VL K+R ES K K L + + ++ T++ D D ++D K+ + +IE ++KL++ +EIGTWSN+MA DD + N+ D DE+ D F LP N+ F + T + G+ G + + G + P D + L S DDD +++ + +I F N AE IE A E KR++ L
Sbjct: 814 LLTGASVDLG--SAIALVNKYCARLPSDTFTKLTALWRCTRNERAGVTLFQYTLRLPINSPLKHDIVGLPMPTQTLARRLAALQACVELHRIGELDDQLQPIGKEGF-RALEPDWECFELEPEDEQIVQLSDEPRPGTTKRRQYYYKRIASEFCDCRPVAGAPCYLYFIQLTLQCPIPEEQNTRGRKIYPPEDAQQGFGILTTKRIPKLSAFSIFTRSGEVKVSLELAKERVILTSEQIVCINGFLNYTFTNVLRLQKFLMLFDPDSTENCVFIVPTVKAPAGGKHIDWQFLELIQ---ANGNTMPRAVPDEERQAQPFDPQRFQDAVVMPWYRNQDQPQYFYVAEICPHLSPLSCFPGDNYRTFKHYYLVKYGLTIQNTSQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVPELCTVHPFPASLWRTAVCLPCILYRINGLLLADDIRKQVSADLGLGRQQIEDEDFEWPMLDFGWSLSEVLKKSRESKQKESLKDDTINGKDLAD---------VEKKPTSEETQL--DKDSKDD-------KVEKSAIELIIEGEEKLQEADDFIEIGTWSNDMA--DDIA---SFNQEDDDED---DAFH-LPVLPANVKFCDQQTRYGSPTFWDVSNGESGFKGPKSSQNKQGGKGKAKGPAKPTFNYYDSDNSLGSSYDDDDNAGPLNYMHHNYSSDDDDVADDIDAGRIAFTSKNEAETIETAQEVEKRQKQL 1529 HSP 3 Score: 110.153 bits (274), Expect = 1.436e-22 Identity = 127/502 (25.30%), Postives = 205/502 (40.84%), Query Frame = 0
Query: 165 RVVTLTANPLHAQG-PLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYG-EEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLK------------------------------------------TMEKY-----ERQFLLLSC-----VHTEMLQLREICGHALDGVSEQDKLTHYVK------------PKMTR-LVEILLQY-------KPSHVGSDVTDDPN-APVAPKKSHRPNKSAPFG-----------SYND-PQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVI-----------ETVEKDLISRSSYQPKAASSD 568
R++ L A PLH+ G L + + LE ++E S+ +++LR P +V+ A E + + VL + FL HR+ E YG ++F D L+DIPDP V P+ ++ V+ ++G W +RAA +KLK T+E+Y R L C VHT+ LR + H +D ++ ++L+H ++ P TR LV L Q + + + VT P A PK S N + P +ND L ++Y + LF L ++SR FL QY V+D +P + +R+E+ L++FR+ + NVL+ + LE G+D +CNLVV +D P + + ++ CK +A+ + VIL T+ + + +T E D S S P ++ SD
Sbjct: 170 RILGL-AGPLHSAGCELQQLSAMLATLEQSVLCQIETASDIVTVLRYCSRPHEYIVQCAP-----FEMDELSLVLADVLNTHKSFLLDHRYDPYEIYGTDQFMDELKDIPDPKVDPLNVINSLLVVLHEMGPWCTQRAAHHFYQCNEKLKVKTPHERHYLLYCLVSTALIQLYSLCEHAFHRHLGSGSDSRQTIERYSSPKVRRLLQTLRCFKPEEVHTQADGLRRM-RHQVDQ-ADFNRLSHTLESKCRMVDQMDQPPTETRALVATLEQILHTTEDRQTNRSAARVTPTPTPAHAKPKPSSGANTAQPRTRRRVYTRRHHRDHNDGSDTLCALIYCNQNHTARVLFELLAEISRRDPDLKFLRCQYT-TDRVADPTTEPKEAELEHRRQEEVLKRFRMHDCNVLIGTSVLEEGIDVPKCNLVVRWDP-PTTYRSYVQCKGRARAAPAYHVILVAPSYKSPTVGSVQLTDRSHRYICATGDTTEADSDSDDSAMPNSSGSD 661
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|229485378|sp|Q6TV19.2|DICER_DANRE (RecName: Full=Endoribonuclease Dicer) HSP 1 Score: 466.463 bits (1199), Expect = 6.996e-134 Identity = 347/1146 (30.28%), Postives = 574/1146 (50.09%), Query Frame = 0
Query: 15 WPWEGVPHETNTPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAG----VAVICVRREKQMTLWAEYFQRVSHASVAEIDVEPPP--PGQHWSVGV----VMATPAKLRQSLEADQFQPL---GLLIIDDGHAHV-------------GCPDLGAILDHAQVRHARVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYE--RQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP------------------SHVG--SDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAASSDLFPGQAVTQSE------ILKTK--SVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHT-SVEGSGHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLK-LEPVAPK-CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEK--FQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTK-KLGSNANRTKSGP 1098
W E + TP + VE + A + + ++ ++ KTF+ L++E+ G V V + A + S V + E P + W+ + V+ + + + PL LL+ D+ H + GCP R++ LTA+ L+ + +IQ LE E ++ + L R P+ +++ Q + +E LL DE L FL ++ ED DPT + +++ D ++V+ LG W A++AA +M ++ K E+ E R+FLL + T + ++ +C S K +V PK+ RL+EIL +YKP ++V DD + K+ N +PF + L GI++++ ++ L +K+ + + +++ ++ G + + V +++E+ LRKFR E N+L+++ +E GVD +CNLVV FD LP + ++ K +A+ P S +++LA E +L + +EK L ++ S K+A + F + VT + +L+++ ++++ + +NRYC++LPSD FT L+P T + G+ S + LPINSP++ P+ G +M A+K+ AL C+ L++ ELD++L P GK+ +K+ + ++ R G K+R K + L+ PV + C++Y + +VL P+PD+ N R RKL+ PE + FG LT++ +P FP+YTRSGEV + + L K L EQ + H Y FS +LRLEK + F + ++PL V +S +D DF K +++ S+ + N + ++ F F +QDAV++P YRN DQP FYVA++Y L+P S FP +E+F +YYK+KY++ +S+ +QPLLDVDHTS+RLN LTPR++ +KG +LP SS E ++ K E+L+ KQILVPELCAIHP ASLWR+ V LP I YRL+ LL A+ LR + A +A VG L P F++ +DFGW + +++ + SA + + KLG++++ + P
Sbjct: 22 WQQEAIHDNIYTPRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLIKELSHQIRGENGKRTVFLVNAASSVAQQASTVRTHSDLQVGDYMSEDMTSWPEEMWNREMIENQVLVMTCHIFLHVLKNGVLPLSKINLLVFDECHLAITGHPYREIMKICEGCPSC-----------PRILGLTASILNGKCDPCDLEEKIQNLEKILQSNAETATDLVVLDRYASQPREEVLDCGQYQDQSGLSER----LLNELDEALNFLNDCNLSVHR----------ED-RDPTFISKQVLNDCRAVLTVLGPWCADKAAGIMVRELQKYIKHEQEELNRKFLLFT--DTILRKIHALCEEHFSPASLDLK---FVTPKVIRLLEILHEYKPFERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEAEAKEKTEANFPSPFTN-----ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHSIGKNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFD-LPTEYRSYVQSKGRARAPVSNYIMLADSERTKTFQEDLKTYKAIEKILRNKCS---KSAECNDFELEPVTDDDNVLPPYVLRSEDGGPRVTMNTAIGHVNRYCARLPSDPFTHLAPKCKTVEMNTGGYRSTLFLPINSPLRVPVTGPVMNCARLAEKAVALLCCEKLHKIGELDDHLMPVGKE-TVKYEEELDLHDEEETSVPGRPGSTKRRQCSPKAIPECLRGCYPVPEQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPRIPHFPVYTRSGEVTISIELQKSGFSLSAEQLELITRLHQYIFSHILRLEKPALEFKPVEADSAYCVLPLNIVEDSN-TLDLDF--KFMEDIEKSEARIGIPNTQYTKQNPFIFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLSNVNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRSQTAIDAGVGAQTLPPDFRYPNLDFGW--KKSIDSKSFISCPSACMEEDDDHCKLGTSSDSNHTAP 1121 HSP 2 Score: 362.844 bits (930), Expect = 2.945e-100 Identity = 191/395 (48.35%), Postives = 268/395 (67.85%), Query Frame = 0
Query: 1538 TQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEE-----EIQV----VSPLNKSVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIR 1923
+ W+ D SK G E++ + + P + N + + + Y+L T+Q I DKSIADCVEAL+G YL + G++ A F+ LG+ V P + + E+Q + P + ER L+HL+ GF FE I Y+F++K+YLLQAFTH SY+ N +TDCYQRLEFLGDA+LD+LIT+HLYEDP++HSPG LTDLRSALVNNTIFA +AVK+ +HK+ +SP L + FV+ Q +KN + + + + + + ED+EVPKA+GD+FES+AGA+++DSG+SL+TVW+++Y MM P I+KF +N+P+SP+RELLE+EPETAKF+ ER DG +VRV+V+V GKG FKGVGR+YRIAK AA+ ALR+++
Sbjct: 1480 SSWDAMCYLDPSKAGEEDDFVVGFWN-----PSEENCGTDIGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPPEKQSSGGSAELQYGWLKIPPRCMFEHPDAERTLNHLISGFLNFESKINYTFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKN------------EMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLK 1856 HSP 3 Score: 130.568 bits (327), Expect = 8.289e-29 Identity = 61/97 (62.89%), Postives = 76/97 (78.35%), Query Frame = 0
Query: 1426 GPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYV 1522
GP+P LILQALT+SNA+D NLERLE +GDSFLK+AIT+ LF YPD EGRLS++RSK+VSN +LY LG +K + M+ + F+P NWLPPGY V
Sbjct: 1273 GPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVV 1369
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|238064965|sp|B3DLA6.2|DICER_XENTR (RecName: Full=Endoribonuclease Dicer) HSP 1 Score: 454.907 bits (1169), Expect = 6.217e-130 Identity = 333/1099 (30.30%), Postives = 546/1099 (49.68%), Query Frame = 0
Query: 15 WPWEGVPHETNTPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAG-------VAVICVRREKQMTLWAEYFQRVSHASVAEIDVEPPP---PGQHWSV-----GVVMATPAKLRQSLEADQ--FQPLGLLIIDDGHAHVGCPDLGAILDHAQVRHA--RVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYE--RQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP--------------SHVGSDVTDDPNAPVAPKKSHRPNKSAPFGSYNDP--QALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHE---SADETLRELDVIETVEKDLISRS------SYQPKAASSDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHTSVEGSG-HLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLKLEPVAPK--CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGP-QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMP---WYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGW 1060
W E + TP + VE + A + + ++ ++ KTF+ L +E+ G V V EKQ++ + + V E + + W + V++ T L++ + LL+ D+ H + I+ + R++ LTA+ L+ + +IQ LE E ++ + L R P E P ++ + LL DE L FL + T+ +E D T++ +++ D Q+V+ LG W A++ A +M ++ K E+ E R+FLL + T + ++ +C S K +V PK+ +L+EIL +YKP + + V+ + + K S+ P L GI++++ ++ L +K+ + + +++ ++ G + + V +++E+ LRKFR E N+L+++ +E GVD +CNLVV FD LP+ + ++ K +A+ P S +++LA + + +E L+ IE + ++ S+S +P ++FP + Q + S ++++ + +NRYC++LPSD FT L+P T G + S + LPINSP++ PI+G M A ++ AL C+ L+E ELD++L P GK+ +K+ + ++ R G K+R Y K + L+ P C++Y + +VL P+PD+ N R RKL+ PE + FG LT++ +P FP+YTRSGEV + + L K L+ EQ + H Y FS +LRLEK + F + ++PL V +SG ID+ F+ + K + +Y+ E F F +QDAV++P YRN DQP FYVA++Y L+P S FP +E+F +YYK+KY++ +++ +QPLLDVDHTS+RLN LTPR++ +KG +LP SS E ++ K E+L+ KQILVPELCAIHP ASLWR+ V LP I YRL+ LL A+ LR + A +A VG L F++ +DFGW
Sbjct: 22 WQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNSGSGKTFIAVLLSKELSYQIRGDFSKNTKRTVFLVNSEKQVSQQVSAVRTHTDLKVGEYSDQEKTQCWAKERWYLEFETHQVLVMTCHIFLNVLKSGNVSLSNINLLVFDECHLAIQDHPYREIMKICESCQPCPRILGLTASILNGKCDPRDLEEKIQKLEEILRSNAETATDLVVLDRYASQP----CEIVLDCGPYIDKSGLYQRLLNELDEALNFLIDCNIS---THSKE--------RDSTLISKQILSDCQTVLLVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFT--DTILRKIHALCEEHFSPASLDMK---FVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDDEDEEIEEKEKTETSFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFD-LPSEYRSYVQSKGRARAPISNYIMLADSDKIKAFEEDLKTYKAIEKILRNKCSKSIDCGNTESEPIVDDDEIFPPYVLRQDD----GSPRVTINTAIGHINRYCARLPSDPFTHLAPKCKTREFPDGLYRSTLYLPINSPLRAPIVGPPMNCGRLADRAVALICCKKLHEIGELDDHLMPVGKE-TVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRNSYPKPGQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLNLEQLELITRLHQYIFSHILRLEKPALEFKPTVADCAYCVLPLNVVNDSGTLDIDFKFVEDIEKSEARTGIPNTQYSAES--PFIFKLEDYQDAVIIPRQVIYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPVPASLWRKAVCLPSILYRLHCLLTAEELRAQTAIDAGVGVKSLPDDFRYPNLDFGW 1092 HSP 2 Score: 350.517 bits (898), Expect = 2.776e-96 Identity = 191/425 (44.94%), Postives = 263/425 (61.88%), Query Frame = 0
Query: 1538 TQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDP-----MQNEEEIQVVSPLNKSVVS----------------------------------EPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIR 1923
+ W+ D SK E++ + + P + N + + + Y+L T+Q I DKSIADCVEAL+G YL + G++ A F+ LG+ V P + N I S S + E+ L HL+ GFE FE I Y F++K+YLLQAFTH SY+ N +TDCYQRLEFLGDA+LD+LIT+HLYEDP++HSPG LTDLRSALVNNTIFA +AVK+ +HK+ +SP L + FV+ Q +KN + + + + + + ED+EVPKA+GD+FES+AGA+++DSG+SL+TVW ++Y MM P I+KF +N+P+SP+RELLE+EPETAKF+ ER DG +VRV+V+V GKG FKGVGR+YRIAK AA+ ALR+++
Sbjct: 1478 SSWDAMCYLDPSKAVEEDDFVVGFWN-----PSEENCGADAGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPEVRKLVTNTNVISASSSYQNSTRDNCTLTARTNTDLSSCKGIDYGYLKIPPRCMFEHPDAEKTLDHLISGFENFEKKINYPFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAISPELFHVIDDFVQFQLEKN------------EMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWHVYYPMMQPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLK 1884 HSP 3 Score: 129.413 bits (324), Expect = 1.956e-28 Identity = 61/97 (62.89%), Postives = 75/97 (77.32%), Query Frame = 0
Query: 1426 GPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYV 1522
GP+P LILQALT+SNA+D NLERLE +GDSFLK+AIT+ LF YPD EGRLS++RSK+VSN +LY LG +K M+ + F+P NWLPPGY V
Sbjct: 1268 GPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGSPSRMVVSIFDPPVNWLPPGYIV 1364
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|257051057|sp|Q8R418.3|DICER_MOUSE (RecName: Full=Endoribonuclease Dicer; AltName: Full=Double-strand-specific ribonuclease mDCR-1) HSP 1 Score: 450.669 bits (1158), Expect = 1.700e-128 Identity = 337/1142 (29.51%), Postives = 554/1142 (48.51%), Query Frame = 0
Query: 15 WPWEGVPHETNTPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLH-------RAGVAVICVRREKQMTLWAEYFQRVSHASVAE---IDVEPPPPGQHWSVGV----VMATPAKLRQSLEADQFQPL---GLLIIDDGHAHVGCPDLGAILDH----------AQVRHARVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYE--RQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP------------------SHVGSDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAASSDLFPG---QAVTQSEILK--TKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHTSVEGSGHL-SGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLKLEPVAPK--CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGP-QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIP 1100
W E + TP + VE + A + + ++ ++ KTF+ L +E+ A V V Q+ + S V E ++V + WS V+ + ++ + + L LL+ D+ H AILDH + R++ LTA+ L+ + +IQ LE E ++ + L R P +V+ P + + LL + L F+ A+ D T++ +++ D ++V+ LG W A++ A +M ++ K E+ E R+FLL + T + ++ +C S K YV PK+ +L+EIL +YKP ++V ++D + ++ +P + P N L GI++++ ++ L +K+ + + +++ ++ G + + +++E+ LRKFR E N+L+++ +E GVD +CNLVV FD LP + ++ K +A+ P S +V+LA + +L + +EK L ++ S A +D+ G + +L+ ++++ + +NRYC++LPSD FT L+P T G S + LPINSP++ I+G M + A++ AL C+ L++ ELDE+L P GK+ +K+ + ++ R G K+R Y K + L+ P C++Y + +VL P+PD+ N R RKL+ PE + FG LT++ +P FP+YTRSGEV + + L K L ++ + H Y FS +LRLEK + F E ++PL V +SG ID+ F+ + K +Y+ E F F +QDAV++P YRN DQP FYVA++Y L+P S FP +E+F +YYK+KY++ +++ +QPLLDVDHTS+RLN LTPR++ +KG +LP SS E ++ K E+L+ KQILVPELCAIHP ASLWR+ V LP I YRL+ LL A+ LR + AS+A VG L F++ +DFGW + +DS+S + N + N + + +P
Sbjct: 32 WQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELAHQIRGDLNPHAKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSDLEVNASWTKERWSQEFTKHQVLIMTCYVALTVLKNGYLSLSDINLLVFDECHL--------AILDHPYREIMKLCESCPSCPRILGLTASILNGKCDPEELEEKIQKLERILRSDAETATDLVVLDRYTSQPCEIVVDCG----PFTDRSGLYERLLMELEAALDFINDCNVAVHSKER-----------DSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFT--DTLLRKIHALCEEYFSPASLDLK---YVTPKVMKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDDDEEIEEKEKPETNFPSPFTN---ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRSKQMEAEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFD-LPTEYRSYVQSKGRARAPISNYVMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSADGAEADVHAGVDDEDAFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMDSVRLAERVVALICCEKLHKIGELDEHLMPVGKE-TVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQQMLELITRLHQYIFSHILRLEKPALEFKPTGAESAYCVLPLNVVNDSGTLDIDFKFMEDIEKSEARIGIPSTKYSKET--PFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPVDFRYPNLDFGW--------KKSIDSKSFISTCNSSLAESDNYCKHSTTVVP 1130 HSP 2 Score: 350.903 bits (899), Expect = 1.900e-96 Identity = 192/426 (45.07%), Postives = 267/426 (62.68%), Query Frame = 0
Query: 1538 TQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDV-------------DPMQNEEEIQ-------VVSPLN------------------KSVVSEP--ERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIR 1923
+ W+ D SK E++ + + P + N + + + Y+L T+Q I DKSIADCVEAL+G YL + G++ A F+ LG+ V DP Q Q +P+ + + P E+ L+HL+ GFE FE I Y F++K+YLLQAFTH SY+ N +TDCYQRLEFLGDA+LD+LIT+HLYEDP++HSPG LTDLRSALVNNTIFA +AVK+ +HK+ +SP L + FVK Q +KN + + + + + + ED+EVPKA+GD+FES+AGA+++DSG+SL+ VW+++Y MM P I+KF +N+P+SP+RELLE+EPETAKF+ ER DG +VRV+V+V GKG FKGVGR+YRIAK AA+ ALR+++
Sbjct: 1500 SSWDAMCYLDPSKAVEEDDFVVGFWN-----PSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSREKALDPAQENGSSQQKSLSGSCAAPVGPRSSAGKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFETFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVKFQLEKN------------EMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMQPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLK 1907 HSP 3 Score: 130.954 bits (328), Expect = 6.038e-29 Identity = 61/97 (62.89%), Postives = 76/97 (78.35%), Query Frame = 0
Query: 1426 GPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYV 1522
GP+P LILQALT+SNA+D NLERLE +GDSFLK+AIT+ LF YPD EGRLS++RSK+VSN +LY LG +K + M+ + F+P NWLPPGY V
Sbjct: 1291 GPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVV 1387
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|257051055|sp|A0MQH0.3|DICER_CRIGR (RecName: Full=Endoribonuclease Dicer) HSP 1 Score: 448.743 bits (1153), Expect = 8.382e-128 Identity = 343/1144 (29.98%), Postives = 555/1144 (48.51%), Query Frame = 0
Query: 15 WPWEGVPHETNTPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLH-------RAGVAVICVRREKQMTLWAEYFQRVSHASVAE---IDVEPPPPGQHWSV-----GVVMATPAKLRQSLEAD--QFQPLGLLIIDDGHAHVGCPDLGAILDH----------AQVRHARVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHR---HALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYE--RQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP------------------SHVGSDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATH---ESADETLRELDVIETVEKDLISRSSYQPKAASSDLFPGQAVTQSEILK--TKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHTSVEGSGHL-SGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLKLEPVAPK--CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGP-QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPI 1099
W E + TP + VE + A + + ++ ++ KTF+ L +E+ RA V V Q+ + S V E ++V + WS V++ T L+ + LL+ D+ H AILDH + R++ LTA+ L+ + +IQ LE E ++ + L R P +V+ P + + LL +E + F+ H+ E D T++ +++ D ++V+ LG W A++ A +M ++ K E+ E R+FLL + T + ++ +C S K YV PK+ +L+EIL +YKP ++V ++D + ++ +P + P N L GI++++ ++ L +K+ + + +++ ++ G + + +++E+ LRKFR E N+L+++ +E GVD +CNLVV FD LP + ++ K +A+ P S +V+LA +S +E L+ IE + ++ S+S +A + V +L+ ++++ + +NRYC++LPSD FT L+P T G S + LPINSP++ I+G M A++ AL C+ L++ ELDE+L P GK+ +K+ + ++ R G K+R Y K + L+ P C++Y + +VL P+PD+ N R RKL+ PE + FG LT++ +P FP+YTRSGEV + + L K L ++ + H Y FS +LRLEK + F E ++PL V +S ID+ F+ + K +Y+ E F F +QDAV++P YRN DQP FYVA++Y L+P S FP +E+F +YYK+KY++ +++ +QPLLDVDHTS+RLN LTPR++ +KG +LP SS E ++ K E+L+ KQILVPELCAIHP ASLWR+ V LP I YRL+ LL A+ LR + AS+A VG L F++ +DFGW + +DS+S + N + L N N K I
Sbjct: 32 WQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELAHQIRGDLNPRAKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWSQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHL--------AILDHPYREIMKLCESCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYASQPCEIVVDCG----PFTDRSGLYERLLMELEEAINFINDCNVSVHSKER--------------DSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFT--DTLLRKIHALCEEHFSPASLDLK---YVTPKVMKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDDDEEIEEKEKPETNFPSPFTN---ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRSKQMEAEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFD-LPTEYRSYVQSKGRARAPISNYVMLADTDKIQSFEEDLKTYKAIEKILRNKCSKSVDGAEADVDAVVDDDDVFPPYVLRPDDGGPRVTINTAIGHVNRYCARLPSDPFTHLAPKCRTQELPDGTFYSTLYLPINSPLRASIVGPPMGCVRLAERVVALICCEKLHKIGELDEHLMPVGKE-TVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQQMLELITRLHQYIFSHILRLEKPALEFKPTGAESAYCVLPLNVVNDSSTLDIDFTFMEDIEKSEARIGIPSTKYSKET--PFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPADFRYPNLDFGW--------KKSIDSKSFISTCNSS--LAENDNYCKHSTI 1127 HSP 2 Score: 348.977 bits (894), Expect = 8.890e-96 Identity = 188/427 (44.03%), Postives = 267/427 (62.53%), Query Frame = 0
Query: 1538 TQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDP-MQNEEEIQVVSPLNKSVVSE----------------------------------------PERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIR 1923
+ W+ D SK E++ + + P + N + + + Y+L T+Q I DKSIADCVEAL+G YL + G++ A F+ LG+ V P ++ + + P ++ S+ E+ L+HL+ GFE FE I Y F++K+YLLQAFTH SY+ N +TDCYQRLEFLGDA+LD+LIT+HLYEDP++HSPG LTDLRSALVNNTIFA +AVK+ +HK+ +SP L + FV+ Q +KN + + + + + + ED+EVPKA+GD+FES+AGA+++DSG+SL+ VW+++Y MM P I+KF +N+P+SP+RELLE+EPETAKF+ ER DG +VRV+V+V GKG FKGVGR+YRIAK AA+ ALR+++
Sbjct: 1500 SSWDAMCYLDPSKAVEEDDFVVGFWN-----PSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSREKALYPAQENFSSQQKSLSGSCAATAASPRSSAGKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFENFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKN------------EMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLK 1908 HSP 3 Score: 130.954 bits (328), Expect = 5.790e-29 Identity = 61/97 (62.89%), Postives = 76/97 (78.35%), Query Frame = 0
Query: 1426 GPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYV 1522
GP+P LILQALT+SNA+D NLERLE +GDSFLK+AIT+ LF YPD EGRLS++RSK+VSN +LY LG +K + M+ + F+P NWLPPGY V
Sbjct: 1291 GPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVV 1387
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|257051054|sp|Q25BN1.3|DICER_CHICK (RecName: Full=Endoribonuclease Dicer) HSP 1 Score: 446.047 bits (1146), Expect = 6.476e-127 Identity = 342/1142 (29.95%), Postives = 554/1142 (48.51%), Query Frame = 0
Query: 15 WPWEGVPHETNTPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAG-------VAVICVRREKQMTLWAEYFQRVSHASVAE---IDVEPPPPGQHWS-------VGVVMATPAKLRQSLEADQFQPLGLLIIDDGHAHVGCPDLGAILDHAQVRHA--RVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHR---HALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYE--RQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP------------------SHVG--SDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHE---SADETLRELDVIETVEKDLISRS------SYQPKAASSDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHT-SVEGSGHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLKLEPVAPK--CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGP-QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPI 1099
W E + TP + VE + A + + ++ ++ KTF+ L +E+ G V V Q+ + S V E ++V + WS V V+ A E + LL+ D+ H + I+ + + R++ LTA+ L+ + +I+ LE E ++ + L R P +V+ P + + LLR DE L FL H+ E D T++ +++ D ++V+ LG W A++ A +M ++ K E+ E R+FLL + T + ++ +C S K +V PK+ +L+EIL +YKP ++V DD + + K+ N +PF + L GI++++ ++ L +K+ + + +++ ++ G + + V +++E+ LRKFR E N+L+++ +E GVD +CNLVV FD LP + ++ K +A+ P S +++LA + S +E L+ IE + ++ S+S +P D+FP + E S ++++ + +NRYC++LPSD FT L+P T + S + LPINSP++ I+G M A++ AL C+ L++ ELD++L P GK+ +K+ + ++ R G K+R Y K + L+ P C++Y + +VL P+PD+ N R RKL+ PE + FG LT++ +P FP+YTRSGEV + + L K L + + H Y FS +LRLEK + F + ++PL V +S ID+ F+ + K + +Y E F F +QDAV++P YRN DQP FYVA++Y L+P S FP +E+F +YYK+KY++ +++ +QPLLDVDHTS+RLN LTPR++ +KG +LP SS E ++ K E+L+ KQILVPELCAIHP ASLWR+ V LP I YRL+ LL A+ LR + A++A VG L F++ +DFGW + +DS+S P+ L N N K I
Sbjct: 32 WQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFNKNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSSLEVTESWTKEKWSQEFSKHQVLVMTCHVALTVLRNEYLSLSNINLLVFDECHLAIQDHPYREIMKICEDYPSCPRILGLTASILNGKCDPAELEEKIKKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCG----PYTDKSGLYGRLLRELDEALHFLNDCNISVHSKER--------------DSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFT--DTFLRKIHALCEEHFSPASLDLK---FVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTN-----ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFD-LPTEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTSETETEPIVDDDDVFPPYVLRTDE----NSPRVTINTAIGHINRYCARLPSDPFTHLAPKCKTRELPDHTFYSTLYLPINSPLRASIVGPPMSCARLAERVVALICCEKLHKIGELDDHLMPVGKE-TVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSLQMLELITRLHQYIFSHILRLEKPALEFKPTEADSAYCVLPLNIVDDSSTLDIDFKFMEDIEKSEARTGIPSTQYTKEM--PFIFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTATDAGVGVKSLPADFRYPNLDFGW--------KKSIDSKS--FISIPSSSLVENENYCKHSTI 1127 HSP 2 Score: 353.599 bits (906), Expect = 3.256e-97 Identity = 195/428 (45.56%), Postives = 271/428 (63.32%), Query Frame = 0
Query: 1538 TQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPM---------------QNEEEIQVVSPLNKS---VVSEP------------------------ERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIR 1923
+ W+ D SK E++ + + P + N + + + Y+L T+Q I DKSIADCVEAL+G YL + G++ A F+ LG+ V P+ E + +SP + S V SEP E+ L+HL+ GFE FE I YSF++K+YLLQAFTH SY+ N +TDCYQRLEFLGDA+LD+LIT+HLYEDP++HSPG LTDLRSALVNNTIFA +AVK+ +HK+ +SP L + FV+ Q +KN + + + + + + ED+EVPKA+GD+FES+AGA+++DSG+SL+ VW+++Y MM P I+KF +N+P+SP+RELLE+EPETAKF+ ER DG +VRV+V+V GKG FKGVGR+YRIAK AA+ ALR+++
Sbjct: 1503 SSWDAMCYLDPSKAVEEDDFVVGFWN-----PSEENCGVDAGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKKTDWESTLCATGENCNSEQKNLSPNSVSACIVNSEPSLYKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFENFEKKINYSFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQMEKN------------EMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEMVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLK 1912 HSP 3 Score: 130.568 bits (327), Expect = 7.216e-29 Identity = 61/97 (62.89%), Postives = 76/97 (78.35%), Query Frame = 0
Query: 1426 GPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYV 1522
GP+P LILQALT+SNA+D NLERLE +GDSFLK+AIT+ LF YPD EGRLS++RSK+VSN +LY LG +K + M+ + F+P NWLPPGY V
Sbjct: 1292 GPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYIV 1388
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|257051053|sp|Q6TUI4.3|DICER_BOVIN (RecName: Full=Endoribonuclease Dicer) HSP 1 Score: 441.039 bits (1133), Expect = 3.464e-125 Identity = 342/1170 (29.23%), Postives = 561/1170 (47.95%), Query Frame = 0
Query: 15 WPWEGVPHETNTPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAG-------VAVICVRREKQMTLWAEYFQRVSHASVAE---IDVEPPPPGQHWSV-----GVVMATPAKLRQSLEAD--QFQPLGLLIIDDGHAHVGCPDLGAILDHAQVR----------HARVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHR---HALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYE--RQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP------------------SHVG--SDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHE---SADETLRELDVIETVEKDLISRS------SYQPKAASSDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHTSVEGSGHL-SGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLKLEPVAPK--CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGP-QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSM---ADITEIFDDDDQ 1116
W E + TP + VE + A + + ++ ++ KTF+ L +E+ G V V Q+ + S V E ++V + W+ V++ T L+ + LL+ D+ H AILDH R++ LTA+ L+ + +IQ LE E ++ + L R P +V+ P + + LL +E L F+ H+ E D T++ +++ D ++V+ LG W A++ A +M ++ K E+ E R+FLL + T + ++ +C S K +V PK+ +L+EIL +YKP ++V D+ + + K+ N +PF + L GI++++ ++ L +K+ + + +++ ++ G + + +++E+ LRKFR E N+L+++ +E GVD +CNLVV FD LP + ++ K +A+ P S +V+LA + S +E L+ IE + ++ S+S +P D+FP + + ++++ + +NRYC++LPSD FT L+P T G S + LPINSP++ I+G M A++ AL C+ L++ ELD++L P GK+ +K+ + ++ R G K+R Y K + L+ P C++Y + +VL P+PD+ N R RKL+ PE + FG LT++ +P FP+YTRSGEV + + L K L + + H Y FS +LRLEK + F + ++PL V +S ID+ F+ + K +Y+ E F F +QDAV++P YRN DQP FYVA++Y L+P S FP +E+F +YYK+KY++ +++ +QPLLDVDHTS+RLN LTPR++ +KG +LP SS E ++ K E+L+ KQILVPELCAIHP ASLWR+ V LP I YRL+ LL A+ LR + AS+A VG L F++ +DFGW + +DS+S N + N + + +P ++ A+ T ++ DQ
Sbjct: 32 WQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFNRNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVSASWTKEKWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHL--------AILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCG----PFTDRSGLYERLLMELEEALNFINDCNISVHSKER--------------DSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKHIKHEQEELHRKFLLFT--DTFLRKIHALCEEHFSPASLDLK---FVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDEEDEEIEEKEKPETNFPSPFTN-----ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFD-LPTEYRSYVQSKGRARAPISNYVMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGEADTEPVVDDDDVFPPYVLRPED-----GPRVTINTAIGHVNRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMSCIRLAERVVALICCEKLHKIGELDDHLMPVGKE-TVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRESYPRPGQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSLQMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYSKET--PFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPVDFRYPNLDFGW--------KKSIDSKSFISIANSSSAENENYCKHSTIVVPENAAHQGANRTSPLENHDQ 1148 HSP 2 Score: 348.206 bits (892), Expect = 1.307e-95 Identity = 188/428 (43.93%), Postives = 266/428 (62.15%), Query Frame = 0
Query: 1538 TQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDP-MQNEEEIQVVSPLNKSVVS-----------------------------------------EPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIR 1923
+ W+ D SK E++ + + P + N + + + Y+L T+Q I DKSIADCVEAL+G YL + G++ A F+ LG+ V P ++ + + + P ++ S E +R L HL+ GFE FE I Y F++K+YLLQAFTH SY+ N +TDCYQRLEFLGDA+LD+LIT+HLYEDP++HSPG LTDLRSALVNNTIFA +AVK+ +HK+ +SP L + FV+ Q +KN + + + + + + ED+EVPKA+GD+FES+AGA+++DSG+SL+TVW+++Y MM P I+KF +N+P+SP+RELLE+EPE KF+ ER DG +VRV+V+V GKG FKGVGR+YRIAK AA+ ALR+++
Sbjct: 1505 SSWDAMCYLDPSKAVEEDDFVVGFWN-----PSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKAMCPTRENFTSQQKNLSGSRAAASGAGYRASVLKDLEYGCLKIPPRCMFDHPEADRTLRHLISGFENFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKN------------EMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPEITKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLK 1914 HSP 3 Score: 111.694 bits (278), Expect = 4.388e-23 Identity = 60/101 (59.41%), Postives = 74/101 (73.27%), Query Frame = 0
Query: 1426 GPSPSLILQALTMSNANDAINLERLETIGDSFLKYAIT----SALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYV 1522
GP+P LILQALT+SNA+D NLERLE +GDSFLK+AIT SAL L D EGRLS++RSK+VSN +LY LG +K + M+ + F+P N LPPGY V
Sbjct: 1291 GPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTVSLSALIL---DAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNGLPPGYVV 1388
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|257051056|sp|Q9UPY3.3|DICER_HUMAN (RecName: Full=Endoribonuclease Dicer; AltName: Full=Helicase with RNase motif; Short=Helicase MOI) HSP 1 Score: 436.032 bits (1120), Expect = 1.210e-123 Identity = 330/1107 (29.81%), Postives = 536/1107 (48.42%), Query Frame = 0
Query: 15 WPWEGVPHETNTPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAG-------VAVICVRREKQMTLWAEYFQRVSHASVAE---IDVEPPPPGQHWSV-----GVVMATPAKLRQSLEAD--QFQPLGLLIIDDGHAHVGCPDLGAILDHAQVR----------HARVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHR---HALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYE--RQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP------------------SHVG--SDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHE---SADETLRELDVIETVEKDLISRSSYQPKAASSDLFPGQAVTQSEILK--TKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHTSVEGSGHL-SGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLKLEPVAPK--CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGP-QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGW 1060
W E + TP + VE + A + + ++ ++ KTF+ L +E+ G V V Q+ + S V E ++V + W+ V++ T L+ + LL+ D+ H AILDH R++ LTA+ L+ + +IQ LE E ++ + L R P +V+ P + + LL +E L F+ H+ E D T++ +++ D ++V+ LG W A++ A +M ++ K E+ E R+FLL + T + ++ +C S K +V PK+ +L+EIL +YKP ++V DD + + K+ N +PF + L GI++++ ++ L +K+ + + +++ ++ G + + +++E+ LRKFR E N+L+++ +E GVD +CNLVV FD LP + ++ K +A+ P S +++LA + S +E L+ IE + ++ S+S + + V +L+ ++++ + +NRYC++LPSD FT L+P T G S + LPINSP++ I+G M A++ AL C+ L++ ELD++L P GK+ +K+ + ++ R G K+R Y K + L+ P C++Y + +VL P+PD+ N R RKL+ PE + FG LT++ +P FP+YTRSGEV + + L K L + + H Y FS +LRLEK + F + ++PL V +S ID+ F+ + K +Y E F F +QDAV++P YRN DQP FYVA++Y L+P S FP +E+F +YYK+KY++ +++ +QPLLDVDHTS+RLN LTPR++ +KG +LP SS E ++ K E+L+ KQILVPELCAIHP ASLWR+ V LP I YRL+ LL A+ LR + AS+A VG L F++ +DFGW
Sbjct: 32 WQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHL--------AILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCG----PFTDRSGLYERLLMELEEALNFINDCNISVHSKER--------------DSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFT--DTFLRKIHALCEEHFSPASLDLK---FVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTN-----ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFD-LPTEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETDIDPVMDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKE-TVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYTKET--PFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPADFRYPNLDFGW 1098 HSP 2 Score: 348.591 bits (893), Expect = 9.886e-96 Identity = 188/428 (43.93%), Postives = 269/428 (62.85%), Query Frame = 0
Query: 1538 TQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDP-MQNEEEIQVVSPLNKSVVSE-----------------------------------------PERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIR 1923
+ W+ D SK E++ + + P + N + + + Y+L T+Q I DKSIADCVEAL+G YL + G++ A F+ LG+ V P ++ + + + P ++ S+ ++ L+HL+ GFE FE I Y F++K+YLLQAFTH SY+ N +TDCYQRLEFLGDA+LD+LIT+HLYEDP++HSPG LTDLRSALVNNTIFA +AVK+ +HK+ +SP L + FV+ Q +KN + + + + + + ED+EVPKA+GD+FES+AGA+++DSG+SL+TVW+++Y MM P I+KF +N+P+SP+RELLE+EPETAKF+ ER DG +VRV+V+V GKG FKGVGR+YRIAK AA+ ALR+++
Sbjct: 1504 SSWDAMCYLDPSKAVEEDDFVVGFWN-----PSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVSCAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKTLNHLISGFENFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKN------------EMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLK 1913 HSP 3 Score: 130.568 bits (327), Expect = 7.403e-29 Identity = 61/97 (62.89%), Postives = 76/97 (78.35%), Query Frame = 0
Query: 1426 GPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYV 1522
GP+P LILQALT+SNA+D NLERLE +GDSFLK+AIT+ LF YPD EGRLS++RSK+VSN +LY LG +K + M+ + F+P NWLPPGY V
Sbjct: 1291 GPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVV 1387
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|408360292|sp|P34529.3|DCR1_CAEEL (RecName: Full=Endoribonuclease dcr-1; Contains: RecName: Full=Death-promoting deoxyribonuclease; Short=tDCR-1) HSP 1 Score: 421.394 bits (1082), Expect = 7.545e-119 Identity = 274/674 (40.65%), Postives = 387/674 (57.42%), Query Frame = 0
Query: 1296 EQFKNEELELIETHPWVWEDTGQSEIMAGNPERA--TTNLKMFAVDKPLDFQINNPQSTP-------EDLS-GPQEPGPVNDPELASRLSAKVKEKLLVLPTS-TEKPPNTPVVKP-----GVIPRDSDRPFGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYY-------------------VPKGLEKALIESGIPS-TQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNKSVVSEPE-----RHLSHLLQGFE--QFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFE--FEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRK 1924
EQFK + +L++ E SE M P R T NL+ + D+ N P + P E+LS G ++ ++D A++ +E VLP + EK + K G + R + D L G SP L+L ALT SNA D ++LER ETIGDSFLK+A T L+ D EG+LS RSK+VSN +LY LG + + + ++ KF+ HD+WLPP Y + + L+ +IE + T W+ DVSK T+ I+ +T P+Q+ +D+ S +PYNLLTQQ I DKSIAD VEALIG +L+ G L M W+G+ V +Q +++ V SPL + + + L++L Q F+ Q E IGY F++++YL+QAFTH SY NR+T CYQRLEFLGDAVLD++ITR+L+ED +++SPG LTDLRSALVNNTIFA +AVKF F K + + PGL + +FVK+ S++NF+ F + Y+V + ED+EVPKA+GD+FESVAGA++LDSG +LDT W++ + MM I+ +N P+SPIREL+E E +F++ ER+ + +VRV+V+V F G+GRNYRIAK TAAK AL+ + +
Sbjct: 1252 EQFKKLQNDLLKQAKERLEALEMSEDME-KPRRLEDTVNLEDYGDDQENQEDENTPTNFPKTIDEEIEELSIGARKKQEIDDN--AAKTDVLERENCEVLPVAINEKSRSFSFEKESKAINGRLIRQRSEEYVSHIDSDIGL----GVSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQLIVANKFDAHDSWLPPCYIPTCDFKAPNTDDAEEKDNEIERILDGQVIEEKPENKTGWDIGG--DVSKSTTDG-----IETITF--PKQARVGNDDI-SPLPYNLLTQQHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKV--IQKDQKSDVPSPLLRFIDTPTNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEI----------DEGQEEDIEVPKAMGDIFESVAGAIYLDSGRNLDTTWQVIFHMMRGTIELCCANPPRSPIRELMEFEQSKVRFSKMERILESGKVRVTVEVVNNMRFTGMGRNYRIAKATAAKRALKYLHQ 1896 HSP 2 Score: 354.369 bits (908), Expect = 1.559e-97 Identity = 289/970 (29.79%), Postives = 467/970 (48.14%), Query Frame = 0
Query: 131 QFQPLGLLIIDDGHAHVGC--PDLGAILDHAQVRH----ARVVTLTANPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKL-KTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSHVGSDVTDDPNAPVAPKKSHRPNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISR--SSYQPKAASSDLFPGQAV-TQSE--ILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHTSV---EGSG---HLSGILLPINSPVKDPI-LGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDF---LLKHVQPNLGPLTPASAQGSRAGPRKQRHYYYKTASKYLKLEPVAP--KCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKY-PMAFN-LGRCEINTLIVPL-KKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKR--------NKRENL-----EQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEA-KVGKVILDPRFQWEPMDFG 1059
+ + + +LI D+ H +G P ++D+ ++ RV+ LTA+ + A+ Q++ LES +E S+ +SL + P ++ + N + V+ DE + F+ T E DL D P ++ R +V R LG WAA R A + ++ K+ K+ ++ L+ T M+ ++ + + + + L YV ++ RL EIL + P K+ + K+ + L I+++ ++ +L ++ + ++ F+ P YV+G+ S + L S KR+ + LR+F E+N L+++ LE GVD +CNLV+ FD P ++ ++ K +A+ S +VI + +L + +EK L+SR + P SD F V +Q E +++ L + + +NRYCSKLPSD FTRL P H + E +G + + +LLPINSP+K I L + MPN A+ + AL+ C+ L+ ELD+NL P G++ LL+H+ P A ++ G K++ Y K ++ L V +C +YA EL N + RK P E FGFL+++ +P PFP++ R G + V++I+ + + Q +++ FH+Y F+ VL++ K + F+ +NTLIVPL K+ + I+ ++ +VV + PK E +++F+ ++DA+VMPWYRN +QP ++YVAEI P S FP FE+F +Y+ KY + I D +Q LLDVD TS RLN L PR + S S+ T +K N Q+QILVPEL IHP A+LW + ALP IFYR+N LL D LR I +A K LD +W + +
Sbjct: 135 KIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKAKVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTVI-EIFDETVAFVN--------TTTEFHPDLDLDPRRPIKDSLKTTR---AVFRQLGPWAAWRTAQVWEKELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIRLFEILETFNPEF--------------QKERMKLEKA---------EHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYVVGA--SGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDR-PLDMRSYVQSKGRARRAGSRYVITVEEKDTAACDSDLKDFQQIEKILLSRHRTVNNPIEDDSDRFEEFDVDSQMEPYVVEKTGATLKMSTAIALINRYCSKLPSDIFTRLVP--HNQIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPKGRESIAKLLEHIDEEPDEYAPGIA--AKVGSSKRKQLYDKKIARALNESFVEADKECFIYAFELERFREAELTLNPKRRKFEDPFNYEYCFGFLSAKEIPKIPPFPVFLRQGNMKVRLIVAPKKTTVTAAQLQEIQLFHNYLFTQVLQMCKTGNLEFDGTSNAPLNTLIVPLNKRKDDMSYTINMKYVSEVVANMENMPRIPKD---EVRRQYKFNAEDYKDAIVMPWYRNLEQPVFYYVAEILPEWRPSSKFPDTHFETFNEYFIKKYKLEIYDQNQSLLDVDFTSTRLNLLQPRIQNQPRRSRTVSNSSTSNIPQASASDSKESNTSVPHSSQRQILVPELMDIHPISATLWNVIAALPSIFYRVNQLLLTDELRETILVKAFGKEKTKLDDNVEWNSLAYA 1059
BLAST of endoribonuclease dcr-1 vs. SwissProt
Match: gi|75330224|sp|Q8LMR2.1|DCL1_ORYSJ (RecName: Full=Endoribonuclease Dicer homolog 1; AltName: Full=Dicer-like protein 1; Short=OsDCL1) HSP 1 Score: 227.639 bits (579), Expect = 1.917e-58 Identity = 171/511 (33.46%), Postives = 255/511 (49.90%), Query Frame = 0
Query: 1420 DLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLGTEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGM--DVDPMQNEEEIQVVSPLNKSVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVK-IQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRN--YRIAKCTAAKCALRAIRKR 1925
D+ +P P+ + IL+ALT ++ + + ER E +GD++LK+ ++ LFL YP EG+L+ +R + VSN LY K + + +F P W PG +P E+ S ++ + D G E + K+ D + E Y +L+ K++AD VEALIG Y +AGGK A M W+G+ ++DP EEI P + PE + + F+ + ++G F++K L++A TH S P+ CYQRLEF+GDAVLD LITRHL+ PG LTDLR+A VNN FA +AVK H L H S L+T FVK +Q + L+ G S G D + PK LGD+ ES+AGA+FLDSG VW++F ++ P + +P P+REL E + A+ + G +V+VF G GV +N ++A+ AA+ AL ++++
Sbjct: 1326 DIIDYPVPA-TKILEALTAASCQETLCYERAELLGDAYLKWVVSRFLFLKYPQKHEGQLTRMRQQMVSNMVLYQYALNKTLQSYIQADRFAP-SRWAAPGV-LPVFDEE--------SREYEPSIF-DEESTGCE-----LQKESYDDYADNMQEDGEIEGDSSCYRVLS-----SKTLADVVEALIGVYYVAGGKIAANHLMKWIGIHAELDP----EEIPPPKPYDI-----PESIMRSI--NFDTLKGVLGIEFQNKGLLVEAITHASR-PSSGVSCYQRLEFVGDAVLDHLITRHLFFTYTDLPPGRLTDLRAAAVNNENFARVAVKHKLHVHLRHGSSALETQIREFVKDVQEE----------LLKPGFNSFGLG------------DCKAPKVLGDIVESIAGAIFLDSGYDTSVVWKVFQPLLHPMVTP--ETLPMHPVRELQERCQQQAEGLEYKASRAGN--IATVEVFVDGVQIGVAQNPQKKMAQKLAARNALVVLKEK 1776 HSP 2 Score: 78.9518 bits (193), Expect = 3.567e-13 Identity = 106/426 (24.88%), Postives = 186/426 (43.66%), Query Frame = 0
Query: 279 IELVRDYQSVVRDLGVWAAERAA--ILMAIKVDK-------LKTMEKYERQFL-LLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSHVGSDVTDDPNAPVAPKKSHRPNKSAPFG---SYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVIL-----ATHESADETLRELDVIETVEKDLISRSSYQPKAASSDLFPGQAVTQS--EILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIF--------HTSVEGSGHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFP 676
I+ +R + +LG W A + A L A++ D+ +K E Y ++ + LL C TE G A+ + ++ + K L E L P G V + A VA K P A Y + R I++++ L L +L SF+ ++G H ++Q + + +D + KFR V +L+++ E G+D +CN+V+ FD L ++ +I + +A+ P S ++++ +HE+ R + ET+ K+ + R+ +S L P S ++ T +V +SL+ + ++ YCS+LPSD ++ L P F SVE S L LP N+P + + G I + A+++ L C+ L+E + L P
Sbjct: 511 IQKLRAINYALGELGQWCAYKVAQSFLTALQNDERANYQVDVKFQESYLKKVVDLLHCQLTE--------GAAMKSETSDVEMQNTEKHNTNDLEEGEL---PDSHGEHVDEVIGAAVADGKV-TPRVQALIKILLKYQHTEDFRAIIFVERVVTALVLPKVLAELP----SLSFIRCASLIG-HNNNQEMRACQM-------QDTISKFRDGRVTLLVATSVAEEGLDIRQCNVVIRFD-LAKTVLAYIQSRGRARKPGSDYILMLERGNISHETFLRNARNSE--ETLRKEAMERTDLSHLDGTSVLSPVDTSPGSMYQVESTGAV-VSLNSAVGLIHFYCSQLPSDRYSILHPEFIMQKYEKPGGSVEYSCKLQ---LPCNAPF-EKLEGPICSSIRLAQQAVCLAACKKLHEMGAFTDTLLP 904 HSP 3 Score: 58.151 bits (139), Expect = 9.119e-7 Identity = 42/136 (30.88%), Postives = 64/136 (47.06%), Query Frame = 0
Query: 907 FYVAEIYQHLSPKSDFPGQG-------FESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQI--LVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALR 1033
FYV I +++ ++ FP + + S+ YYK KY + + QPL+ S N L+PR+ S+ + + ENL++ L PELC +HP SL R LP I R+ S+L A L+
Sbjct: 1199 FYVDCICYNMNAENSFPRKEGYLGPLEYSSYADYYKQKYGVELIYRKQPLIRARGVSYCKNLLSPRF---------EHSDAREGDFSENLDKTYYVYLPPELCLVHPLPGSLVRGAQRLPSIMRRVESMLLAVQLK 1325
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|607356231|gb|EZA50771.1| (Endoribonuclease Dcr-1 [Ooceraea biroi]) HSP 1 Score: 1357.43 bits (3512), Expect = 0.000e+0 Identity = 818/2048 (39.94%), Postives = 1179/2048 (57.57%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAGV-------AVICVRREKQMTLWAEYFQRVSHASV--AEIDVEPPPPGQHWSVGVVMATPAKLRQSLEADQFQP--LGLLIIDDGHAHVGCPDLGAILDHAQV--RHARVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSH----------VGSDV-------TDDPNA--------PVAPKKSHRPNKSAPFGSYN-------------DPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAK------KREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS----SDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSP---IFHTSVEGSG-HLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQ----GSRAGPRKQRHYYYK-TASKYLKLEP-VAPKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITEIFDDDDQEEDGS---TDNLGKLNDRLLNTLIEEDQKLKQKS--LEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDD---SDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHP------WVWEDTGQSEIMAGN----------PERATTNLKMF-AVDKPLDFQINNPQSTPEDLSGPQEPGPVNDPELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPRDS----DRPFGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLG----------TEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPM-------QNEEEIQV------VSPLNKS----------------------VVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKR 1925
TP E VE + A + ++ + + +TFL L++E + + A+ + E + + Y ++++ V + D+ S V++ TP Q + + P + L+I+D+ H + +L IL + R++ L N G LGL +I+ +E+ + VE ++ LS++R P+ +VE+A+ + + + +E+ +L + FL HR+ E Y EEF + ++ IPDP P E+++D+ ++ LG W A+RAA+ + I +KLK YER +LLL+ + T +++R +C + +SE++K+ Y PK+ RL++IL Y P + + +DV D +A P A K R N +Y DP L G++++ F K +F+ L ++S+ E FL P Y + + D +G A+ +++E+ L++FR+ E N+L+S+ LE G+D +CN V+ +D P + + ++ CK +A+ +++ V+L E++ E + +L + +EK L+ + S + +D++ + + +++ + + +NRYC+KLPSDTFTRL+P I + +G + + LPINSP+K + MPN A++ AAL++C L++ E+D+NL P GK+ + P P ++ +R G K+R YYYK TA + P V ++Y + +VL CP+P++QNTRGR+++ PE + FG LT + +P CPFPIYTRSGEV V++ L KE + L+E Q ++ F +YTF++VLRL+KY M F+ E + +IVP+K S +DWDFL + + + P + EE + F+FD + + DAV+MPWYR+QDQPQYFYVAEI +L+PKS FPG + +FE+YY KY I I + +Q LLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+ L+ F+W +DFGW+L +VLK ++E AK + + + +++N S I D ++ +E S TD +L + E ++++ QKS LEIGTWSN+MA +D A + ++ D E+L ++ P N+T +LP +D+G R GSPT + G D SDG +D+ D+ ED E KI + G N+AEA+ED ++I ++EI ++ L+L+ET W++ + + ++ + ER N F + D + + N S D P E + K +++L + E +T VK + ++ D F FSFDYQP+L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVPK LE+ALIESG+PST WN A +P + + TEE+++ M +L + SN +++R F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FM WLG+ V P +NE E ++ V ++S + +PE L +L G+E+ E IGY FRD SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + +RFV+IQ + +++YL+GE E EDVEVPKALGDVFES+AGA++LDSG+SLD VW ++Y +M +I++F +N+PKSPIRELLELEPETAKF RPE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ ++ +
Sbjct: 15 TPREYQVELLYAAKERNIIVCLGKNSEQTFLAIKLIQEFATNNRRLITEGGKRAMYILNDEDKCVIIGTYIKQLTDLKVLACDSDILKEFVDSVESSHVLVGTPKVYAQLMTESKLLPCHINLVIVDECHKSIEDSNLKFILRTFLLCDNVPRIIGLAVPVFNLTQEPGRLGL---EIEKVEAAFQCGVETANDILSIIRYSPKPREYVVEYAKGEKGNL-YDTLESCVLHAIE----FLRDHRYDPMEIYTEEFYEDIQKIPDPIQKPFEMLQDFLHILETLGPWCADRAALALLILTEKLKIKTPYERHYLLLNMMTTVFIKIRALCDNEFQHLSEKEKIYQYSTPKVHRLLQILKTYTPFYTKEINTPEKKINADVDVKNCVTKSDRDASLSRIEEKPAAHSKKFRTNWKFNDDNYKRTSKSQRHPCNTMDPDLLCGVIFVDKGFTAKVVFYLLNEISKHDEDLHFLSPLYTIERNTDD-------IGYARDLEMEYRKQEEVLKRFRIHECNLLISTSILEEGIDIPKCNFVMRYD-FPRNYQSYVQCKSRARAIDALHVLLVPQETSKELIWQLAQYQYIEKTLLLKCSNKELTEEEENEADMYTAMIPHYKPLDGADAPKVTFNSAISLVNRYCAKLPSDTFTRLTPEWSINTVKINDTGMYTCSLRLPINSPLKYVVTSYPMPNRAMARRMAALQMCIDLHQENEIDDNLLPIGKENFKAKPEDAEVPALPDESRVDFSEARPGTTKRRQYYYKKTAEALMDCRPIVGTPSYLYHINMVLSCPLPEEQNTRGRRIYPPEESAIGFGILTLKEIPKLCPFPIYTRSGEVHVQLKLSKESVILNEVQLEKIDTFLNYTFTNVLRLQKYLMLFDPNASENSYIIVPVKIYKGSDVSVDWDFLECI---YQNRNAVPTKVPEEERKTFKFDSSKYHDAVIMPWYRSQDQPQYFYVAEICTNLNPKSSFPGHDYSTFEEYYLKKYGIQIQNLEQSLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVAQMINLGQENLNSDFEWPALDFGWSLAEVLKRSK--ETEKAKQTKSENVQCNASSNNVISN--------KCQNILDQENNKEKASFNETDKPIELESDGTDKTDEANEEIDQKSNELEIGTWSNDMAWSNDI----AIDSINYDAENL-------KSFPLNVT-----VLP-------QDFGWN----DIRYGSPTC----ESDFDGYESDDIYSDGF--ADTSDESED-------ESRGLKISYMGENVAEAVED-EKQICKQEINKKI----LDLLETEKNYDNNFWMYAEKDEEVLLMKHKEAHYEFTKKKERDIMNDGTFISCDSEIMMKRRNSLSCQIDKEQPN----CKHEEYTKTIVKKFIDEVL----NKEPSKSTQSVKKEISMQNKISYLDNEF-FSFDYQPELKGHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPKELEQALIESGVPSTLWNQADIPTLQAVNPSEITQLVKETEEKLVIMKSELDKNESRLSNTL-DNLRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMTWLGIHVLPAKEICVVSENEPEDRIPGSTPYVKEFDESDETTWTQMYYGKLEEPQNPLLRYIPDPENELHMMLDGYEELEKNIGYKFRDSSYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDSRQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSVVINRFVRIQEENGHSISEEYYLIGE-------------DECEEAEDVEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYAIMKSEIEQFSTNVPKSPIRELLELEPETAKFGRPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKSK 1965
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|759070052|ref|XP_011344594.1| (PREDICTED: endoribonuclease Dcr-1 [Ooceraea biroi] >gi|759070054|ref|XP_011344595.1| PREDICTED: endoribonuclease Dcr-1 [Ooceraea biroi]) HSP 1 Score: 1353.96 bits (3503), Expect = 0.000e+0 Identity = 818/2050 (39.90%), Postives = 1182/2050 (57.66%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAGV-------AVICVRREKQMTLWAEYFQRVSHASV--AEIDVEPPPPGQHWSVGVVMATPAKLRQSLEADQFQP--LGLLIIDDGHAHVGCPDLGAILDHAQV--RHARVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSH----------VGSDV-------TDDPNA--------PVAPKKSHRPNKSAPFGSYN-------------DPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAK------KREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS----SDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSP---IFHTSVEGSG-HLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQ----GSRAGPRKQRHYYYK-TASKYLKLEP-VAPKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGP--QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITEIFDDDDQEEDGS---TDNLGKLNDRLLNTLIEEDQKLKQKS--LEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDD---SDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHP------WVWEDTGQSEIMAGN----------PERATTNLKMF-AVDKPLDFQINNPQSTPEDLSGPQEPGPVNDPELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPRDS----DRPFGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLG----------TEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPM-------QNEEEIQV------VSPLNKS----------------------VVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKR 1925
TP E VE + A + ++ + + +TFL L++E + + A+ + E + + Y ++++ V + D+ S V++ TP Q + + P + L+I+D+ H + +L IL + R++ L N G LGL +I+ +E+ + VE ++ LS++R P+ +VE+A+ + + + +E+ +L + FL HR+ E Y EEF + ++ IPDP P E+++D+ ++ LG W A+RAA+ + I +KLK YER +LLL+ + T +++R +C + +SE++K+ Y PK+ RL++IL Y P + + +DV D +A P A K R N +Y DP L G++++ F K +F+ L ++S+ E FL P Y + + D +G A+ +++E+ L++FR+ E N+L+S+ LE G+D +CN V+ +D P + + ++ CK +A+ +++ V+L E++ E + +L + +EK L+ + S + +D++ + + +++ + + +NRYC+KLPSDTFTRL+P I + +G + + LPINSP+K + MPN A++ AAL++C L++ E+D+NL P GK+ + P P ++ +R G K+R YYYK TA + P V ++Y + +VL CP+P++QNTRGR+++ PE + FG LT + +P CPFPIYTRSGEV V++ L KE + L+E Q ++ F +YTF++VLRL+KY M F+ E + +IVP+K +++ G +DWDFL + + + P + EE + F+FD + + DAV+MPWYR+QDQPQYFYVAEI +L+PKS FPG + +FE+YY KY I I + +Q LLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+ L+ F+W +DFGW+L +VLK ++E AK + + + +++N S I D ++ +E S TD +L + E ++++ QKS LEIGTWSN+MA +D A + ++ D E+L ++ P N+T +LP +D+G R GSPT + G D SDG +D+ D+ ED E KI + G N+AEA+ED ++I ++EI ++ L+L+ET W++ + + ++ + ER N F + D + + N S D P E + K +++L + E +T VK + ++ D F FSFDYQP+L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVPK LE+ALIESG+PST WN A +P + + TEE+++ M +L + SN +++R F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FM WLG+ V P +NE E ++ V ++S + +PE L +L G+E+ E IGY FRD SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + +RFV+IQ + +++YL+GE E EDVEVPKALGDVFES+AGA++LDSG+SLD VW ++Y +M +I++F +N+PKSPIRELLELEPETAKF RPE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ ++ +
Sbjct: 15 TPREYQVELLYAAKERNIIVCLGKNSEQTFLAIKLIQEFATNNRRLITEGGKRAMYILNDEDKCVIIGTYIKQLTDLKVLACDSDILKEFVDSVESSHVLVGTPKVYAQLMTESKLLPCHINLVIVDECHKSIEDSNLKFILRTFLLCDNVPRIIGLAVPVFNLTQEPGRLGL---EIEKVEAAFQCGVETANDILSIIRYSPKPREYVVEYAKGEKGNL-YDTLESCVLHAIE----FLRDHRYDPMEIYTEEFYEDIQKIPDPIQKPFEMLQDFLHILETLGPWCADRAALALLILTEKLKIKTPYERHYLLLNMMTTVFIKIRALCDNEFQHLSEKEKIYQYSTPKVHRLLQILKTYTPFYTKEINTPEKKINADVDVKNCVTKSDRDASLSRIEEKPAAHSKKFRTNWKFNDDNYKRTSKSQRHPCNTMDPDLLCGVIFVDKGFTAKVVFYLLNEISKHDEDLHFLSPLYTIERNTDD-------IGYARDLEMEYRKQEEVLKRFRIHECNLLISTSILEEGIDIPKCNFVMRYD-FPRNYQSYVQCKSRARAIDALHVLLVPQETSKELIWQLAQYQYIEKTLLLKCSNKELTEEEENEADMYTAMIPHYKPLDGADAPKVTFNSAISLVNRYCAKLPSDTFTRLTPEWSINTVKINDTGMYTCSLRLPINSPLKYVVTSYPMPNRAMARRMAALQMCIDLHQENEIDDNLLPIGKENFKAKPEDAEVPALPDESRVDFSEARPGTTKRRQYYYKKTAEALMDCRPIVGTPSYLYHINMVLSCPLPEEQNTRGRRIYPPEESAIGFGILTLKEIPKLCPFPIYTRSGEVHVQLKLSKESVILNEVQLEKIDTFLNYTFTNVLRLQKYLMLFDPNASENSYIIVPVK-ISDKGSDVSVDWDFLECI---YQNRNAVPTKVPEEERKTFKFDSSKYHDAVIMPWYRSQDQPQYFYVAEICTNLNPKSSFPGHDYSTFEEYYLKKYGIQIQNLEQSLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVAQMINLGQENLNSDFEWPALDFGWSLAEVLKRSK--ETEKAKQTKSENVQCNASSNNVISN--------KCQNILDQENNKEKASFNETDKPIELESDGTDKTDEANEEIDQKSNELEIGTWSNDMAWSNDI----AIDSINYDAENL-------KSFPLNVT-----VLP-------QDFGWN----DIRYGSPTC----ESDFDGYESDDIYSDGF--ADTSDESED-------ESRGLKISYMGENVAEAVED-EKQICKQEINKKI----LDLLETEKNYDNNFWMYAEKDEEVLLMKHKEAHYEFTKKKERDIMNDGTFISCDSEIMMKRRNSLSCQIDKEQPN----CKHEEYTKTIVKKFIDEVL----NKEPSKSTQSVKKEISMQNKISYLDNEF-FSFDYQPELKGHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPKELEQALIESGVPSTLWNQADIPTLQAVNPSEITQLVKETEEKLVIMKSELDKNESRLSNTL-DNLRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMTWLGIHVLPAKEICVVSENEPEDRIPGSTPYVKEFDESDETTWTQMYYGKLEEPQNPLLRYIPDPENELHMMLDGYEELEKNIGYKFRDSSYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDSRQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSVVINRFVRIQEENGHSISEEYYLIGE-------------DECEEAEDVEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYAIMKSEIEQFSTNVPKSPIRELLELEPETAKFGRPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKSK 1966
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|1153709170|ref|XP_020299785.1| (endoribonuclease Dcr-1 [Pseudomyrmex gracilis]) HSP 1 Score: 1352.42 bits (3499), Expect = 0.000e+0 Identity = 806/2039 (39.53%), Postives = 1156/2039 (56.69%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAGVA-------VICVRREKQMTLWAEYFQRVSHASV---AEIDVEPPPPGQHWSVGVVMATPAKLRQSLEADQFQP--LGLLIIDDGHAHVGCPDLGAILDHAQVRHA--RVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSHV-----------------GSDVTDDPNAPVAPKKSHRPNKSAPFG---------------------SYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS----SDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSP---IFHTSVEGSG-HLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTP----ASAQGSRAGPRKQRHYYYK-TASKYLKLEPVAPK-CHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAE---SGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITE---IFDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLKQKSLEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDDSDGLSCSDSDDDMEDDRHFVTEEDGTS-KIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHP------WVWEDTGQSEIM----AGNPERATTNLKMFAVDKPL-----DFQINNPQSTPEDLSGPQEPGPVND--PELASRLSAKVKEKLLVLPT-STEKPPNTPVVKPGVIPRDSDRPFGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLG----------TEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQN---------EEEIQVVSPLNKSV--------------------------VSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKR 1925
TP E VE + A + ++ + + +TFL L++E + +A + + + + T+ Y ++++ V + ++ V++ TP Q + + P + L+I+D+ H + +L IL + + R++ L N G LGL +I+ +E+ + VE ++ S++R P+ +VE+A + E + +E+ +L + FL HR+ E Y EEF + ++ IPDP P E+++D+ V+ LG W A+RAA+ + I +KLK YER +LLL+ + + +++R IC + +SE++K+ Y PK+ RL++IL Y P + D+ DD + V K +P + FG S DP +L G++++ F K LF+ L ++ + E FL P Y + + D + V +++E+ L++FR+ E N+L+++ LE G+D +CN V+ +D P + +I CK +A+ ++++V+L E + + + +L + +EK L+ + S + +D++ + + +++ + + +NRYC+KLPSDTFTRL+P I +++ + + + LPINSP+K + MPN A++ AAL++C L+ E+D+NL P GK+ + P P A +R G K+R YYYK TA+ P+ + ++Y + +VL CP+P++QNTRGR+++ PE + FG LT + +P CPFPIYTRSGEV V++ L K+ + LDE Q +V F +YTF++VLRL+KY M F+ E + +IVP+ K+ S +DWDFL + + + P + E+ + F+FD + + DAV+MPWYR+QDQPQYFYVAEI +L+PKS FPGQ + +FE+YY KY I I + +Q LLDVDHTSARLNFLTPRYV RKG++LPT+SEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+ L F+W +DFGW+L +VLK + E +K S + S+ + T +++ + + ++ +E+ +D + + I +DQK LEIGTWSN+MA D N D +MD DM ++ P N+T +LP +D+G R GSPT D DG D D DD +E++ KI + G N+AEA+ED + K ++ + L+L+ET W++ + + ++ + E A T + D + I S+ + Q D + + + +V K V T EK + + K + FSFDYQP+L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPPGYYVPK LE+ALIESG+PST WN A +P + + TEE+++ M +L S+N +D+R F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FM WLG+ V P + EE I +P K + V +PE L +L G+E+ E IGY FRD SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED + HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + +RFV++Q + D++YL+GE E EDVEVPKALGDVFES+AGA++LDSG+SLD VW ++Y +M +I++F +N+PKSPIRELLELEPETAKF RPE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ ++ +
Sbjct: 15 TPREYQVELLYAAKEKNIIVCLGKNTEQTFLAIKLIQEFATNNRRLASNGGKRAIFILNDKDKSTIIGTYIKQLTDLKVLACNDCNINEKFAEDFNISHVLVGTPNVYAQLISEKKLLPCHINLVIVDECHKCIEDNNLKFILQTFLLCNNVPRIIGLAVPVFNLTQEPGRLGL---EIEKVETTFQCEVETANDIFSIVRYSPKPREYVVEYA-KGEKKDLYNTLESCVLHAIE----FLQDHRYDPMEIYTEEFYEDIQKIPDPIQKPFEMMQDFLHVLETLGPWCADRAALALLILTEKLKIKTPYERHYLLLNMMTSVFIKIRAICDNEFQHLSEKEKIYRYTTPKVHRLLKILKTYTPFYTKEAITPEKKTNTETDTQNCDLKDDKDTSV--KTPEKPAQVKRFGGNWKSNDDNYKKMPKSQRYLYSNADPDSLCGVIFVDKGFIAKVLFYLLNEICKHDEDLHFLSPLYAIEKNTDDNSCS-RDVESEHRKQEEVLKRFRIHECNLLIATSMLEEGIDIPKCNFVMRYD-FPKDYQSYIQCKSRARAVDALYVLLVPQEVSKDFIWQLAQYQYIEKTLLLKCSNKELTEEEESEADMYAAMIPHYKPLDDDDAPKVTFNSAISLINRYCAKLPSDTFTRLTPEWFIETVNIQNTTMYTCSLRLPINSPLKYVVTSYPMPNKAMARRMAALQMCIDLHRENEIDDNLLPIGKENFKAKPEDAEVPALPDENKADFSEARPGTTKRRQYYYKKTAAALTNCRPIVGQPSYLYHISMVLTCPLPEEQNTRGRRIYPPEESAIGFGILTLKEIPKLCPFPIYTRSGEVYVQLKLSKQTVILDEIQLKKVDTFLNYTFTNVLRLQKYLMLFDPNTSENSYIIVPVNKLTTDEGSDISVDWDFLECI---YQNRNAIPIKIPEEDRKNFEFDPSKYYDAVIMPWYRSQDQPQYFYVAEICTNLNPKSSFPGQDYSTFEEYYLKKYGIQIQNLEQSLLDVDHTSARLNFLTPRYVNRKGVALPTTSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANEIRCQVAQMINLGQQNLSSDFEWPALDFGWSLAEVLKRSKEI--EKSKQSKTENVQANSSLDSTVVSNKCQNTEQNTNNSNILCNETKSQEELQSDKTDETEEE-----ITDDQK---DELEIGTWSNDMAWSKDIVVNSMDYDMD-------DM----KSFPLNVT-----VLP-------QDFGWN----DIRYGSPT-----------CESDYDGYESDDMYSDGFDDTTDESEDESRGLKISYMGENIAEAVEDEKQMCK-----QEMNKKILDLLETEKNFDNNFWMYTKSDEELLLEKHKKAHYEYAKTKEQDIMNDGTFLSYDSEITIKRKSSSIYQTNKEQPNCKYRDYIESVVKKFTDEVLNKKFVASTKKIEKSESNKLNKNNYLDNGL-----FSFDYQPELKNHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPGYYVPKELEQALIESGVPSTFWNQANIPTLQTVNPTEITQLVKETEEKLVIMKNELDKTENRLSSNF-DDLRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMTWLGIHVLPAEQIYVISEDEPEERIPGSTPFVKEINEHGETMWTHICYGRLEEPQNPLFRYVLDPENELYMMLDGYEELEESIGYKFRDSSYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDSRLHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSVVINRFVRLQEENGHTISDEYYLIGE-------------DECEEAEDVEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYTIMKSEIEQFSTNVPKSPIRELLELEPETAKFRRPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKGK 1966
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|572305342|ref|XP_006618601.1| (PREDICTED: endoribonuclease Dcr-1-like [Apis dorsata]) HSP 1 Score: 1345.87 bits (3482), Expect = 0.000e+0 Identity = 819/2029 (40.36%), Postives = 1165/2029 (57.42%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAGV-------AVICVRREKQMTLWAEYFQRVSHASVAEIDVEPPPPG-QHWSVGVVMATPAKLRQSLEADQF---QPLGLLIIDDGHAHVGCPDLGAILDHAQVRHA--RVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP---SHVGSDVTDDPNAPVAPK-----------------------KSHRPNKSAPFGS------YNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS----SDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSP---IFHTSVEGS-GHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQ----GSRAGPRKQRHYYYK-TASKYLKLEPV-APKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITE-IFDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLKQKSLEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDD---SDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHP----WVWEDTGQSEIMAGNPERATTNLKMFAVDKPLDFQINNPQSTPED---LSGPQEPGPVNDPELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPRDSDRP-FG-------FSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLG----------TEEEILSMIKDLTSDRPEQS-NNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNK-----------------------------------SVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKRSN 1927
TP E VE A D ++ + + +TFL+ L++E + + ++ + E++ T+ A Y Q+++ V D P + + + V+ T +K L AD+ + L+I+D+ H + L IL + R++ L N G LGL +I+ +E+ + VE S+ LS+LR P+ +VE+A+ + + IE +L + FL HR+ E Y EEF + ++ IPDPT P E+++D ++ LG W A+RAA + I +KLK YER +LLL+ + + ++R +C +A + +SE++K+ Y K+ RL++IL Y P H+ + N ++ K KS N P + DP L G++++ F K LF+ L ++S E+ FL P Y + ++ D + + +++E+ L++FR+ E N+L+S+ LE G+D +CN V+ +D P + + ++ CK +A+ P++++V+L + E + E + +L +EK L+ + S + +D++ + + +++ + + +NRYC+KLPSDTFTRL+P I S++ ++ + LPINSPVK + MPN A++ AAL++C L+ E+D+NL P GK+ + P P ++ +R G K+R YYYK TA P+ ++Y + LVL CP+P++QNTRGR+++ PE + FG +T + +P CPFPIYTRSGEV VK+ L K+ + L+E Q ++ F +YTF++VLRL++Y M F+ E + +IVP+K +S +DW+FL + K + P + E + F+FD + + DAV+MPWYR+QDQPQYFYVAEI +L+PKS FPG + +FE+YY KYDI I + DQPLLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+ L+ F+W +DFGW+L +VLK SE AK+ N +NA TK I + DITE ++ D ++ + S ND++ T E+ + LEIGTWS++MA N +D +L ++ P N+T L NE +W R GSP + G D SDG +D+ D+ ED E+ +I + G N+AEA+ED ++I ++E+ ++ L+L+ET +W +SEI+ + A FA K + + N P D + + ++ E K + +V + E N ++P I ++S+ P F FSFD+QP L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVPK LE+ALIESG+PST WN A +P + + TE+++ M +L DR E + N ++MR F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FMAWLG+ V P + IQ P ++ + +PE L +L G+E+ E IGY F D SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + +RFV+IQ + +++YL+GE + VEVPKALGDVFES+AGA++LDSG+SLD VW ++Y +M +I++F +N+PKSPIRELLELEPETAKF +PE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ +++ N
Sbjct: 15 TPREYQVELFYAAKDKDIIVCLGKNYEQTFLVIKLIQEFATNNRRLLSEGGKRSLYILTDEEKCTIKASYIQQLTDLKVLLCDTCPTAEFIEKFEISHVLLTTSKTCAQLLADKKILPHQINLVIVDECHKSINNSQLKFILQTILSCNNVPRIIGLAVPLFNLTQEPGRLGL---EIEKVENTFQCEVETASDILSILRYSPKPKEYVVEYAKSEKGELHI-TIENHILHAIE----FLRDHRYDPTEIYNEEFYEDIQKIPDPTEKPFEMMQDLLHILETLGPWCADRAAFALLILTEKLKIKTPYERHYLLLNMIASVFTKIRALCDNAFEVLSEKEKIYKYTTTKVHRLLQILKTYTPYYTKHINNTDNKINNENISRKFSTNNRDSIKDKFMQSKKLDCNWKSSEENCKKPLLAQRHMRGITDPDLLCGVIFVDKAFVAKVLFYLLNEISMHDEELHFLSPLYTIEKNIDDINYSKD-LEIEHRKQEEVLKRFRIHECNILISTSILEEGIDIPKCNFVMRYD-FPKTYQSYVQCKSRARAPDALYVLLVSQEMSKEYVWQLAQYHYIEKTLLVKCSNNEPSEEEENEADMYAAMIPHYKPLDGGDAPKVTFNSAISLVNRYCAKLPSDTFTRLTPEWSIQEMSIDNILMYICSLRLPINSPVKYIVSSYPMPNKAMARRMAALQLCIDLHRKNEIDDNLLPIGKENFKAKPEDAEVPALPDESKVDFSEARPGTTKRRQYYYKKTAEALTDCRPIIGVPSYLYHINLVLSCPLPEEQNTRGRRIYPPEESAIGFGIITLKEIPKLCPFPIYTRSGEVHVKLKLTKQTIILNEMQVEKIATFLNYTFTNVLRLQQYLMLFDPNASENSYMIVPVKLDEQSDIAVDWNFLECIYK---NRNTGPTKIPEEARKNFKFDASKYHDAVIMPWYRSQDQPQYFYVAEICTNLNPKSSFPGNDYGTFEEYYLKKYDIQIQNLDQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVAQMINLGQENLNSDFEWPALDFGWSLAEVLKKSKE--SEKAKLIRNELN--STNAIDTKCQNISK----DITENLYKLDKKDLNESNYEFQLTNDKVTET--EQQISNDENELEIGTWSSDMAM----------NSLDFGANNL-------KSFPLNVTVLPNEF----------NWN------DIRYGSPAC----ESDFDGYESDDIYSDGF--ADTSDESED-------ENRGLRISYMGENVAEAVED-EKQISKQEVNKRI----LDLLETEKNSDEILWSYAKESEILITKHKLAHYE---FAKIKECEIK-QNGSFIPYDNKIVIKRKTSFSLHSEENLPNYKYKTYVETVVDKFTQEILNNNETIQP--IKKNSNTPKFTYHFDSNLFSFDFQPKLENHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPKELEQALIESGVPSTLWNQADIPALQAVNPFEITQLVRETEQKLGVMKNEL--DRNETTLPNNLDNMRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMAWLGIHVLPTEEINIIQETEPKDRIPGSTPFVKGKNEKGQTIWTQIRYGKLEEPQNPLLRYIVDPEEELKLMLDGYEELEKNIGYKFHDISYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDARQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSIVINRFVRIQEENGHSISEEYYLIGEEECEEAED-------------VEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYAIMKNEIEQFSTNVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKRMQN 1948
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|1000768131|ref|XP_015607216.1| (PREDICTED: endoribonuclease Dcr-1 isoform X1 [Cephus cinctus]) HSP 1 Score: 1341.25 bits (3470), Expect = 0.000e+0 Identity = 815/2031 (40.13%), Postives = 1151/2031 (56.67%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVC------LHRAGVAVICVRRE-KQMTLWAEYFQRVSHASVAEIDVEPPPPGQHW-----SVGVVMATPAKLRQSLEADQFQP--LGLLIIDDGHAHVGCPDLGAILDH--AQVRHARVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSH------VGSDVTDDPNA---------PVAPKKSH--------RPN----KSAP-----FGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAASSDLFPGQAVTQSEILKTKSVE----LSLDKGLWCLNRYCSKLPSDTFTRLSP-IFHTSVEGSG---HLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQG----SRAGPRKQRHYYYK-TASKYLKLEPV-APKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKV-AESGP--QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITE---IFDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLKQKSLEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDDSDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIET------HPWVWEDTGQSEIMAGNPERATTNLKMFAVDKPLDFQINNPQSTPEDLSGPQEPGPVNDPELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPRDSDRPFG-----------FSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLP--------DVSKLGTEEEILSMIKDLTSDRPEQS-NNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNKSVVS-----------------------------------EPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRK 1924
TP E VE + A + ++ + + +TF++ L++E+ + G I + +E + + A Y Q+++ V V PG+ + + V++ T L+ P + L+++D HA + DL +L + R++ L N G LGL +I+ +E+ + VE S+ LS+LR P+ +VE+ E N+ L + FL HR+ E Y EEF + ++ IPDPT P E++ D+ V+R LG W A+RAA+ + I +KLK YER +LL + V + +++R +C +G+SE++++ + PK+ RL++IL Y P H + + +D N P+ H RP+ K +P S DP L G++++ F K LF+ L ++ + + FL P Y + V D + V + +++E+ L++FR+ E N+L+++ LE G+D +CN V+ +D P S + ++ CK +A+ +++ V+L + + + L +EK L+++ S + +L + K V+ +S + + +NRYC+KLPSDTFTRL+P F +V+ ++ + LPINSPVK + MPN A++ AAL++C L+ E+D+NL P GK+ + P P ++ +R G K+R YYYK TA P+ ++Y + ++L CP+P++QNTRGR+++ PE + FG LT + +P CPFPIYTRSGEV VK+ L KE + LDE Q +V F +YTF++VLRL+KY M F+ E + +IVP+K V E+GP +DWDFL + K + P + ++ + F+FD + + DAV+MPWYRNQDQPQYFYVAEI +L+PKS FPG + +FE+YY KY+I I + +QPLLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+V L+ F+W P+DFGW+L +VLK E+ K + + + + +N + KS S++D E +D D +E ++ ++ +EE ++ K LEIGTWSNEMA N M+ + E++ ++ P NLT L + W R GSP + ++ G D +CS+ D D+ +E +I + G N+AEA+ED +I +REI ++ L+L+E + W + ++ E+ FA K + N + D + +N+ +AK E + E N + K + RP FSFDYQP+L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVP+ LE+ALIESG+PST WN A +P D+++L E E I + D+ E N + R F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FMAWLG+ V P + Q P+ + S +PER L +L G+ Q E IGY F+D SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + RFV+IQ + +++YL+GE + VEVPKALGDVFES+AGA++LDSG+SLD VW ++YR+M +I++F +N+PKSPIRELLELEPETAKF +PE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ +++
Sbjct: 15 TPREYQVELLYAAKERNIIVCLGKYSEQTFIVIKLIQELATNNRRSIAEGGKRAIYILKEFDKCIIKATYVQQLTDLKVL---VCNENPGKEFMDDFTNTNVLVTTSDVCAHLLQVQNILPSQINLVVVDQCHASLKDGDLNIVLQTFLSCKNGPRIIGLAVPLFNLTEEPGVLGL---EIEKVENTFYCEVETASDILSILRYSPKPKEYIVEYKDG-----EKGNLHEALENCAVHAMEFLRDHRYDPTEIYNEEFLEDIQKIPDPTDKPCEMIEDFLYVLRTLGPWCADRAALALLILTEKLKVKTPYERHYLLFNVVASVFIKIRALCESEFEGLSERERIYQFSMPKVHRLLKILKTYTPFHSKDSHNIDNKANNDANVKTESNKELIPIRENHMHFRKFGSNWRPHEEGYKRSPKSLRHLRSVTDPDLLCGVIFVDRAFTAKILFYLLNEVCKHDQDLHFLSPLYTIEKTVDDMSY-ARDVEMEHRKQEEVLKRFRIHECNLLIATSILEEGIDIPKCNFVMRYD-FPKSYQSYVQCKSRARAIDALHVLLVPEKESKICVWRLAQYHYIEKILLTKCSNKEPTEEEELEADKYAAMIPQYKPLDVDDAPSVSFNSAISLVNRYCAKLPSDTFTRLTPEWFIDTVDIDNTIMYICSLRLPINSPVKYVVSSYPMPNRAMARRLAALQLCVKLHRENEIDDNLLPIGKENFKAKPEDAEVPALPDESKADFSEARPGTTKRRQYYYKKTAEALTDCRPIIGVPSYLYHINMMLSCPLPEEQNTRGRRIYPPEESAIGFGILTLKEIPKLCPFPIYTRSGEVHVKLKLSKETVILDEVQIERVAAFLNYTFTNVLRLQKYLMLFDPNASENSYIIVPVKTVITENGPDVNVDWDFLDCIYK---NRNTVPNQVPEKDRKYFKFDPSKYHDAVIMPWYRNQDQPQYFYVAEICGNLNPKSSFPGADYSTFEEYYLKKYNIQIQNLNQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVARTINLGQVHLNSNFEWPPLDFGWSLAEVLKK----SKETEKANESKNEAVRNNIDVDKS------SISDKIENKLAYDKDSLDESA-------ISKETIDPELEEIEESKDNELEIGTWSNEMAM----------NSMEFNSENI-------KSFPMNLTVLQPDF----------SWND------IRYGSPAC----DSDLDGYESDD---TCSEGLIDFSDESE---DESRGLRIAYMGENVAEAVED-ENQICKREINKKI----LDLLEVERSSDENTWTCLENMNDSLL----EKHKATHYEFAQKKEREIIDNGSFISGSDEITIKRKNSLNNQADGKEPNAKYTE---YIAKVVENFKNEVLKKKHEVAPVKKRPSTSALTFHKEESLFSFDYQPELKGHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPRELEQALIESGVPSTLWNQADIPALQAVNPTDITQLVRETEHKLGIMRIELDKNESCLTNDLDTFRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMAWLGIHVLPTEEVCIFQDTEPVERYPGSTPYVKRINEYGKTIWTQIRYGKLEEPQYPLLRHTPDPERELKTMLDGYNQLEENIGYKFQDTSYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDSRQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSVVIDRFVRIQEENGHSISEEYYLIGEEECEEAED-------------VEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYRIMKSEIEQFSTNVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKR 1944
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|1000768133|ref|XP_015607218.1| (PREDICTED: endoribonuclease Dcr-1 isoform X2 [Cephus cinctus]) HSP 1 Score: 1339.71 bits (3466), Expect = 0.000e+0 Identity = 814/2030 (40.10%), Postives = 1150/2030 (56.65%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVC------LHRAGVAVICVRRE-KQMTLWAEYFQRVSHASVAEIDVEPPPPGQHW-----SVGVVMATPAKLRQSLEADQFQP--LGLLIIDDGHAHVGCPDLGAILDH--AQVRHARVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSH------VGSDVTDDPNA---------PVAPKKSH--------RPN----KSAP-----FGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAASSDLFPGQAVTQSEILKTKSVE----LSLDKGLWCLNRYCSKLPSDTFTRLSP-IFHTSVEGSG---HLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQG----SRAGPRKQRHYYYK-TASKYLKLEPV-APKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGP--QIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITE---IFDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLKQKSLEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDDSDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIET------HPWVWEDTGQSEIMAGNPERATTNLKMFAVDKPLDFQINNPQSTPEDLSGPQEPGPVNDPELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPRDSDRPFG-----------FSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLP--------DVSKLGTEEEILSMIKDLTSDRPEQS-NNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNKSVVS-----------------------------------EPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRK 1924
TP E VE + A + ++ + + +TF++ L++E+ + G I + +E + + A Y Q+++ V V PG+ + + V++ T L+ P + L+++D HA + DL +L + R++ L N G LGL +I+ +E+ + VE S+ LS+LR P+ +VE+ E N+ L + FL HR+ E Y EEF + ++ IPDPT P E++ D+ V+R LG W A+RAA+ + I +KLK YER +LL + V + +++R +C +G+SE++++ + PK+ RL++IL Y P H + + +D N P+ H RP+ K +P S DP L G++++ F K LF+ L ++ + + FL P Y + V D + V + +++E+ L++FR+ E N+L+++ LE G+D +CN V+ +D P S + ++ CK +A+ +++ V+L + + + L +EK L+++ S + +L + K V+ +S + + +NRYC+KLPSDTFTRL+P F +V+ ++ + LPINSPVK + MPN A++ AAL++C L+ E+D+NL P GK+ + P P ++ +R G K+R YYYK TA P+ ++Y + ++L CP+P++QNTRGR+++ PE + FG LT + +P CPFPIYTRSGEV VK+ L KE + LDE Q +V F +YTF++VLRL+KY M F+ E + +IVP+K E+GP +DWDFL + K + P + ++ + F+FD + + DAV+MPWYRNQDQPQYFYVAEI +L+PKS FPG + +FE+YY KY+I I + +QPLLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+V L+ F+W P+DFGW+L +VLK E+ K + + + + +N + KS S++D E +D D +E ++ ++ +EE ++ K LEIGTWSNEMA N M+ + E++ ++ P NLT L + W R GSP + ++ G D +CS+ D D+ +E +I + G N+AEA+ED +I +REI ++ L+L+E + W + ++ E+ FA K + N + D + +N+ +AK E + E N + K + RP FSFDYQP+L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVP+ LE+ALIESG+PST WN A +P D+++L E E I + D+ E N + R F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FMAWLG+ V P + Q P+ + S +PER L +L G+ Q E IGY F+D SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + RFV+IQ + +++YL+GE + VEVPKALGDVFES+AGA++LDSG+SLD VW ++YR+M +I++F +N+PKSPIRELLELEPETAKF +PE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ +++
Sbjct: 15 TPREYQVELLYAAKERNIIVCLGKYSEQTFIVIKLIQELATNNRRSIAEGGKRAIYILKEFDKCIIKATYVQQLTDLKVL---VCNENPGKEFMDDFTNTNVLVTTSDVCAHLLQVQNILPSQINLVVVDQCHASLKDGDLNIVLQTFLSCKNGPRIIGLAVPLFNLTEEPGVLGL---EIEKVENTFYCEVETASDILSILRYSPKPKEYIVEYKDG-----EKGNLHEALENCAVHAMEFLRDHRYDPTEIYNEEFLEDIQKIPDPTDKPCEMIEDFLYVLRTLGPWCADRAALALLILTEKLKVKTPYERHYLLFNVVASVFIKIRALCESEFEGLSERERIYQFSMPKVHRLLKILKTYTPFHSKDSHNIDNKANNDANVKTESNKELIPIRENHMHFRKFGSNWRPHEEGYKRSPKSLRHLRSVTDPDLLCGVIFVDRAFTAKILFYLLNEVCKHDQDLHFLSPLYTIEKTVDDMSY-ARDVEMEHRKQEEVLKRFRIHECNLLIATSILEEGIDIPKCNFVMRYD-FPKSYQSYVQCKSRARAIDALHVLLVPEKESKICVWRLAQYHYIEKILLTKCSNKEPTEEEELEADKYAAMIPQYKPLDVDDAPSVSFNSAISLVNRYCAKLPSDTFTRLTPEWFIDTVDIDNTIMYICSLRLPINSPVKYVVSSYPMPNRAMARRLAALQLCVKLHRENEIDDNLLPIGKENFKAKPEDAEVPALPDESKADFSEARPGTTKRRQYYYKKTAEALTDCRPIIGVPSYLYHINMMLSCPLPEEQNTRGRRIYPPEESAIGFGILTLKEIPKLCPFPIYTRSGEVHVKLKLSKETVILDEVQIERVAAFLNYTFTNVLRLQKYLMLFDPNASENSYIIVPVK--TENGPDVNVDWDFLDCIYK---NRNTVPNQVPEKDRKYFKFDPSKYHDAVIMPWYRNQDQPQYFYVAEICGNLNPKSSFPGADYSTFEEYYLKKYNIQIQNLNQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVARTINLGQVHLNSNFEWPPLDFGWSLAEVLKK----SKETEKANESKNEAVRNNIDVDKS------SISDKIENKLAYDKDSLDESA-------ISKETIDPELEEIEESKDNELEIGTWSNEMAM----------NSMEFNSENI-------KSFPMNLTVLQPDF----------SWND------IRYGSPAC----DSDLDGYESDD---TCSEGLIDFSDESE---DESRGLRIAYMGENVAEAVED-ENQICKREINKKI----LDLLEVERSSDENTWTCLENMNDSLL----EKHKATHYEFAQKKEREIIDNGSFISGSDEITIKRKNSLNNQADGKEPNAKYTE---YIAKVVENFKNEVLKKKHEVAPVKKRPSTSALTFHKEESLFSFDYQPELKGHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPRELEQALIESGVPSTLWNQADIPALQAVNPTDITQLVRETEHKLGIMRIELDKNESCLTNDLDTFRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMAWLGIHVLPTEEVCIFQDTEPVERYPGSTPYVKRINEYGKTIWTQIRYGKLEEPQYPLLRHTPDPERELKTMLDGYNQLEENIGYKFQDTSYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDSRQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSVVIDRFVRIQEENGHSISEEYYLIGEEECEEAED-------------VEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYRIMKSEIEQFSTNVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKR 1941
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|383862048|ref|XP_003706496.1| (PREDICTED: endoribonuclease Dcr-1 isoform X1 [Megachile rotundata]) HSP 1 Score: 1339.32 bits (3465), Expect = 0.000e+0 Identity = 815/2029 (40.17%), Postives = 1165/2029 (57.42%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVC------LHRAGV-AVICVRREKQMTLWAEYFQRVSHASVAEIDVEPPPP--GQHWSVGVVMATPAKLRQSLEADQFQP--LGLLIIDDGHAHVGCPDLGAILDH--AQVRHARVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPS---------------------HVGSDVTDDPNAPVAPKKSHRPNKSAPFG------SYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS----SDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSPIFHTSVEGSG----HLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQ----GSRAGPRKQRHYYYK-TASKYLKLEPV--APKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRT-KSGPIPRDSMADITEI----FDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLKQKSLEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDD---SDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHP-----WVWEDTGQSEIMAGNPERATTNLKMFAVDKPLDFQI--NNPQSTPEDLSGPQEPGPVNDP--ELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPRDSDRPFG-------FSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLP--------DVSKLGTE-EEILSMIKD-LTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQN---------EEEIQVVSPLNKSV--------------------------VSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKRSN 1927
TP E VE A + ++ + + +TF++ L++E L G ++ + E++ + A Y Q+++ V + + V++ T + L + P + L+I+D+ H + L IL + R++ L N G LGL +I+ +E+ + VE S+ LS+LR + +VE+ + + I+ +L + FL HRH E Y EEF + ++ IPDPT P E+++D+ V+ LG W A+RAA+ + I +KLK YER +LLL+ V + +++R +C +A + +S+++++ Y PK+ RL+++L Y P HV + + + +K + N PF DP L G++++ F K LF+ L ++S E FL P Y + + D + + + K++E+ L+KFR+ E N+L+S+ LE G+D +CN V+ +D P + + ++ CK +A+ +++ V+L E++ E + +L +EK L+ + S + +D++ + + + +++ + + +NRYC+KLPSDTFTRL+P + S ++ + LPINSPVK + MPN A++ AAL++C L+ E+D+NL P GK+ + P P + +R G K+R YYYK TA+ P+ AP ++Y + +VL C +P++QNTRGR+++ PE + FG +T + +P CPFPIYTRSGEV V++ L K + L+E Q ++ F +YTF++VLRL++Y M F+ E + +IVP+K ES +DW+FL + + + P + E+ + F+FD + +QDAV+MPWYRNQDQPQYFYVAEI +L+PKS FPG + +FE+YY KY+I I + DQPLLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+ L P F+W +DFGW+L +VLK SE KV+ T + S +N K +P +M + E+ +D + E + DN L D+ L EE + LEIGTWSN+MA N +D + L ++ P N+T L N +W R GSP + G + D SDG +D+ D+ ED E+ +I + G N+AEAIED ++I ++EI ++ L+L+ET W + + + ++A + L + K + +I N + ++ + N P + +S K + +V +TE N + +P V + + F FSFD+QP+L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVPK LE+ALI+SGIPST WN A +P ++++L E E+ L ++KD L + SNN +++R F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FMAWLG+ V PM+ EE I +P K + PE+ L +L G+E+ E IGY F D SYLLQAFTH SY PN+LTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + +RFV+IQ + +++YL+GE E EDVEVPKALGDVFES+AGA++LDSG+SLD VW ++Y +M +I++F +N+PKSPIRELLELEPETAKF +PE+L+DG RVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ +++ N
Sbjct: 15 TPREYQVELFYAARDKNIIVCLGKSYEQTFIVIKLIQEFAANNRRPLSEGGKRSLYILTDEEKCIIKASYIQQLTDLKVLMYTACSSNEFVDKFETSHVLVLTSEVCTKLLAEKKILPHQINLVIVDECHKFINDNKLKFILQTFLSCTDVPRIIGLAVPLFNLTQEPGRLGL---EIEKVETTFQCEVETASDILSILRYSPKAKEYIVEYCNGEKGELHI-TIKNYILHAIE----FLRDHRHDPTEIYNEEFYEDIQKIPDPTEKPFEMMQDFLHVLETLGPWCADRAALALLILTEKLKIKTPYERHYLLLNMVASVFMKIRALCDNAFEILSDKERIYKYTTPKVHRLLQVLKTYTPYYNKDVKNSDSKINGENSSQKLHVNNRENYIRDKFIHGRKGNEENDKRPFKFQRHMRGATDPDLLCGVIFVDKGFVAKVLFYLLNEISAHDEDLEFLSPLYTIERNTDDVSYSKD-LEIEHKKQEEVLKKFRIHECNLLISTSILEEGIDIPKCNFVMRYD-FPKTYQSYVQCKSRARAIDALHVLLVPKETSKECIWQLAQYHYIEKTLLIKCSNNEPSEEEENEADMYAAMIPHYKPLSEDDAPKVTFNSAISLVNRYCAKLPSDTFTRLTPEWSIEQINSDNMPMYVCSLRLPINSPVKYAVSSYPMPNRAMARRMAALQLCIDLHRKNEIDDNLLPIGKENFKAKPEDAEVPALPDEIKVDFSEARPGTTKRRQYYYKKTANALTDCRPIVGAPS-YLYHINMVLSCALPEEQNTRGRRIYPPEESAIGFGIITLKEIPKLCPFPIYTRSGEVHVQLKLSKCTVVLNEIQIEKISTFLNYTFTNVLRLQQYLMLFDPNASENSYMIVPVKLDTESDVTVDWEFLECI---YNNRTTVPTKVPEEDRKDFKFDASKYQDAVIMPWYRNQDQPQYFYVAEICTNLNPKSSFPGDDYSTFEEYYFKKYEIQIQNLDQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVAQMINLGQQNLAPDFEWPALDFGWSLAEVLKKSKE--SEKTKVAKTETTQSNSLSNTVEKYQAMPEKTMNNFNELDMEDLNDKEYELELENDN---LTDKELEISNEEQE------LEIGTWSNDMAV----------NAIDCETNDL-------KSFPVNVTVLPNNF----------NWSD------IRYGSPAC----ESDYDGYVSDDIYSDGF--ADTSDESED-------ENRGLRISYMGENVAEAIED-EKQISKQEINKKI----LDLLETEKNLDTLWSYTEEKEESLIAKH------KLTHYEFTKLRECEIMENGSFISCDNEIIIKRKNSFNSPFEDNSSDYRHKPYVQNIVNKFTTEVLNNNNISQP-VKQKSNSSKFTYHPSNNLFSFDFQPELENHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPKELEQALIKSGIPSTLWNQADIPTLQAVNPNEITQLVRETEQKLGIMKDELVRNEAILSNNL-DNLRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMAWLGIHVLPMEEICIVQETEPEERIPGSTPYVKGTNDQGEVTWIQIRYGKLEEPQNPLLRYIPNPEQELLMMLDGYEELEKNIGYKFNDISYLLQAFTHASYQPNKLTDCYQRLEFLGDAVLDYLITRHLYEDARQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSVVINRFVRIQEENGHSISEEYYLIGE-------------EKCEEAEDVEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYVIMKNEIEQFSTNVPKSPIRELLELEPETAKFGKPEKLADGHRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKQMQN 1946
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|1059215385|ref|XP_017754466.1| (PREDICTED: endoribonuclease Dcr-1 [Eufriesea mexicana]) HSP 1 Score: 1337.78 bits (3461), Expect = 0.000e+0 Identity = 812/2034 (39.92%), Postives = 1169/2034 (57.47%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVC------LHRAGV-AVICVRREKQMTLWAEYFQRVSHASVAEIDVEPPPPG-QHWSVGVVMATPAKLRQSLEADQF---QPLGLLIIDDGHAHVGCPDLGAILDH--AQVRHARVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKPSHV-----GSDVTDDPNAPVAPKKSHR---------------------------PNKSAPFGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS----SDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSP---IFHTSVEGS-GHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQ----GSRAGPRKQRHYYYK-TASKYLKLEPV-APKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITEIFDDDDQEEDGSTDNLGKLNDRLL-NTLIEEDQKL--KQKSLEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDD---SDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHP------WVWEDTGQSEIMAGNPERATTNLKMFAVD-------KPLDFQINNPQSTPEDLSGPQEPGPVNDPELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPR---DSDRPFGFSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLG----------TEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVV------------SPLNKSV--------------------------VSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKRSN 1927
TP E VE A D ++ + + +TF++ L++E L + G ++ ++ E++ + A Y Q+++ V D + + + V+ T + L D+ + L+I+D+ H V L IL + AR++ L N G LGL +I+ +E+ + VE S+ LS+LR P+ +VE+ + + + IE +L D FL HRH E Y EEF + ++ IPDPT P E+++D+ ++ LG W A+RAA+ + I +KLK YER +LLL+ V + ++R +C A + +SE++++ Y PK+ RL++IL Y P + +D ++ N ++R P+++ DP L G++++ F K LF+ L ++S E FL P Y++ ++ D +G+ K++E+ L++FR+ E N+L+S+ LE G+D +CN V+ +D P + + ++ C+ +A+ ++++V+L E++ E + +L +EK L+ + S + +DL+ G + + +++ + + +NRYC+KLPSD FTRL+P I +++ + ++ + LPINSPVK + MPN A++ AAL++C L+ E+D+NL P GK+ + P P ++ +R G K+R YYYK TA P+ ++Y + LVL CP+P++QNTRGR+++ PE + FG +T + +P CPFPIYTRSGEV VK+ L K+ + L+E Q ++ F +YTF++VLRL++Y M F+ E + +IVP+K +S +DW+FL + K + P + + E + F+FD + + DAV+MPWYR+QDQPQYFYVAEI +L+PKS FPG G+ +FE+YY KYDI I + DQPLLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELC IHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+ L F+W +DFGW+L +VLK SE K++ N T +L S N++K DI D+ + G D L + N L N ++E +Q++ + LEIGTWS++MA N D E+++ ++ P N+T L N+ +W R GSP + G D SDG D+ D+ ED E+ +I + G N+AEA+ED ++I ++EI ++ L+L+E+ W + + ++ ++ + + K+ D P D +I + T L + + K +++L +K P+ K IP+ SD FSFD+QP L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVPK LE+ALIESG+PST WN A +P + + TE+++ M +L +R + N ++M F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FMAWLG+ V P EEI +V +P K++ + +PE+ L +L G+E+ E IGY F D SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + +RFV+IQ + +++YL+GE + VEVPKALGDVFES+AGA++LDSG+SLD VW ++Y +M +I++F +N+PKSPIRELLELEPETAKF +PE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ +++ N
Sbjct: 15 TPREYQVELFYAAKEKDIIVCLGKNYEQTFIVIKLIQEFATNNRRLLSKGGKRSLYILKDEEKCIIKASYIQQLTDLKVLLCDTCSLAEFIEKFEISHVLVTTFETCAQLLTDKKILPHQINLVIVDECHKSVDNNKLKFILQTILSCENVARIIGLAVPLFNLTQEPGRLGL---EIEKVENTFQCEVETASDILSILRYSPKPKEYVVEYTKSEKGELHT-TIENYILHAID----FLRDHRHDPTEIYNEEFYEDIQKIPDPTEKPFEMMQDFLYILDSLGPWCADRAALALLILTEKLKIKTPYERHYLLLNMVASVFTKIRALCDSAFEVLSERERIFKYSTPKVHRLLQILKTYTPYYTKNINNSNDKINNENISQKLSTNNREGFMKDKFVQFKKLDCNWQNNEENCKEPSRAQHMRGVMDPDLLCGVIFVDKAFVAKVLFYLLNEISMHDEDLHFLSPLYMIERNIDDIGYS-RDLGIEHKKQEEVLKRFRIHECNLLISTSILEEGIDIPKCNFVMRYD-FPKTYQSYVQCRSRARATDALYVLLVPQETSREYVWQLAQYHYIEKSLLVKCSNNEPSEEEENEADLYAGMIPHYKPLDGDDTPKVTFNSAISLVNRYCAKLPSDIFTRLTPEWVIHKMNIDNTLMYICSLRLPINSPVKYVVSSFPMPNKAMARRMAALQLCIDLHRKNEIDDNLLPIGKENFKAKPEDAEVPALPDESKVDFSEARPGTTKRRQYYYKKTAETLTDCRPIIGIPSYLYHINLVLSCPLPEEQNTRGRRIYPPEESAIGFGIITLKEIPKLCPFPIYTRSGEVHVKLKLSKQTVILNEIQIEKIAAFLNYTFTNVLRLQQYLMLFDPNASENSYMIVPVKLDEKSDVIVDWNFLECIYK---NRNSGPTKISEEVRKNFKFDASKYHDAVIMPWYRSQDQPQYFYVAEICTNLNPKSSFPGDGYSTFEEYYLKKYDIQIQNLDQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCTIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVAQMINLGQETLSSDFRWPALDFGWSLAEVLKKSKE--SEKTKLARNDTIELNSTNNQSK----------DIV-----DNLHKSGKED-LNEDNCELKSNIIMETNQQVLNDENELEIGTWSSDMAM------NSLDFEINN-----------LKSFPLNVTVLPNDF----------NWSD------IRYGSPAC----ESDFDGYESDDIYSDGF--VDTSDESED-------ENRGLRISYMGENVAEAVED-EKQISKQEINKKI----LDLLESEKNLDDILWSYVEESENSSISKHKQAHYEFAKIREFDIMQSEYFIPCDNEIVIKRKTSVSLQPDENLSDYRHKTYIENVVDKFTKEIL-----NKKDIIQPIKKNSNIPKFTYHSDNNL-FSFDFQPKLENHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPKELEQALIESGVPSTLWNQADIPALQAVNSSEITQLVRETEQKLGVMKNEL--NRNDMLPNNLDNMCCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMAWLGIHVLPT---EEISIVQETEPKERIPGSTPYIKALNEKGQTVWTQICYGKLEEPQNPLLRYIPDPEQELRMMLDGYEELEKSIGYKFHDISYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDARQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSIVINRFVRIQEENGHSISEEYYLIGEEECEEAED-------------VEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYAIMKNEIEQFSTNVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKRMQN 1942
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|820858448|ref|XP_003696618.2| (PREDICTED: LOW QUALITY PROTEIN: endoribonuclease Dcr-1 [Apis florea]) HSP 1 Score: 1336.24 bits (3457), Expect = 0.000e+0 Identity = 811/2033 (39.89%), Postives = 1158/2033 (56.96%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVCLHRAGV-------AVICVRREKQMTLWAEYFQRVSHASVAEIDVEPPPPG-QHWSVGVVMATPAKLRQSLEADQF---QPLGLLIIDDGHAHVGCPDLGAILDHA-QVRHARVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP---SHVGSDVTDDPNAPVAPK-----------------------KSHRPNKSAP------FGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS----SDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSP---IFHTSVEGS-GHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQ----GSRAGPRKQRHYYYK-TASKYLKLEPV-APKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITE-IFDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLKQKSLEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDD---SDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHP----WVWEDTGQSEIMAGNPERA--------TTNLKMFAVDKPLDFQINNPQSTPEDLSGPQEPGPVNDPELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPRDSDRP-FG-------FSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLG----------TEEEILSMIKDLTSDRPEQS-NNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNK-----------------------------------SVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKRSN 1927
TP E VE A D ++ + + +TFL+ L++E + + ++ + E++ + A Y Q+++ + D + + + V+ T +K L D+ + L+I+D+ H + L IL + R++ L N G LGL +I+ +E+ + VE S+ LS+LR P+ +VE+A + E + ++ + FL HR+ E Y EEF + ++ IPDPT P E+++D ++ LG W A+RAA + I +KLK YER +LLL+ + + ++R +C +A + +SE++K+ Y K+ RL++IL Y P H+ + N ++ K KS N P DP L G++++ F K LF+ L ++S E+ FL P Y + ++ D + + + +++E+ L++FR+ E N+L+S+ LE G+D +CN V+ +D P + + ++ CK +A+ P++++V+L + E + E + +L +EK L+ + S + +D++ + + +++ + + +NRYC+KLPSDTFTRL+P I +++ ++ + LPINSPVK + MPN A++ AAL++C L+ E+D+NL P GK+ + P P ++ +R G K+R YYYK TA P+ ++Y + LVL CP+P++QNTRGR+++ PE + FG +T + +P CPFPIYTRSGEV VK+ L K+ + L+E Q ++ F +YTF++VLRL++Y M F+ E + +IVP+K +S +DW+FL + K + P + E + F+FD + + DAV+MPWYR+QDQPQYFYVAEI +L+PKS FPG + +FE+YY KYDI I + DQPLLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+ L+ F+W +DFGW+L +VLK SE AK+ N +NA TK I + DITE ++ D ++ + S ND++ T E+ + LEIGTWS++MA N +D +L ++ P N+T L NE +W R GSP + G D SDG +D+ D+ ED E+ +I + G N+AEA+ED ++I ++E+ ++ L+L+ET +W +SE++ A +K P D +I + T L + N P + + +V + E N ++P I ++S+ P F FSFD+QP L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVPK LE+ALIESG+PST WN A +P + + TE+++ M +L DR E + N ++MR F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FMAWLG+ V P + IQ P ++ + +PE L +L G+E+ E IGY F D SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + +RFV+IQ + +++YL+GE + VEVPKALGDVFES+AGA++LDSG+SLD VW ++Y +M +I++F +N+PKSPIRELLELEPETAKF +PE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ +++ N
Sbjct: 15 TPREYQVELFYAAKDKDIIVCLGKNYEQTFLVIKLIQEFATNNRRLLSEGGKRSLYILTDEEKCIVKASYIQQLTDLKILLCDTCSTAEFIEKFEISHVLLTTSKTCAQLLTDKKILPHQINLVIVDECHKSINNSQLKFILQTILSCNNVRIIGLAVPLFNLTQEPGRLGL---EIEKVENTFHCEVETASDILSILRYSPKPKEYVVEYA-----KSEKGELHIIIENHILHAIEFLRDHRYDPTEIYNEEFYEDIQKIPDPTEKPFEMMQDLLHILETLGPWCADRAAFALLILTEKLKIKTPYERHYLLLNMIASVFTKIRALCDNAFEVLSEKEKIYKYTTTKVHRLLQILKTYTPYYTKHINNTDNKINNENISRKFSANNRDSIKDKFMQSKKLDCNWKSSEENCKKPPVAQRHMRGITDPDLLCGVIFVDKAFVAKVLFYLLNEISIHDEELHFLSPLYTIEKNIDDISYSKD-LEIEHRKQEEVLKRFRIHECNILISTSILEEGIDIPKCNFVMRYD-FPKTYQSYVQCKSRARAPDALYVLLVSQEMSKEYVWQLAQYHYIEKTLLVKCSNNEPSEEEENEADMYAAMIPHYKPLDGGDAPKVTFNSAISLVNRYCAKLPSDTFTRLTPEWSIQEMNIDNILMYICSLRLPINSPVKYIVSSYPMPNKAMARRMAALQLCIDLHRKNEIDDNLLPIGKENFKAKPEDAEVPALPDESKVDFSEARPGTTKRRQYYYKKTAEALTDCRPIIGVPSYLYHINLVLSCPLPEEQNTRGRRIYPPEESAIGFGIITLKEIPKLCPFPIYTRSGEVHVKLKLSKQTIILNEMQVEKIATFLNYTFTNVLRLQQYLMLFDPNASENSYMIVPVKLDEQSDIAVDWNFLECIYK---NRNTGPTKIPEETRKNFKFDASKYHDAVIMPWYRSQDQPQYFYVAEICTNLNPKSSFPGNDYGTFEEYYLKKYDIQIQNLDQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVAQMINLGQENLNSDFEWPALDFGWSLAEVLKKSKE--SEKAKLIRNEVN--STNAIDTKCQNISK----DITENLYKLDKEDLNESNYEFQLTNDKITET--EKQISNDENELEIGTWSSDMAM----------NSLDFGTNNL-------KSFPLNVTVLPNEF----------NWN------DIRYGSPAC----ESDFDGYESDDIYSDGF--ADTSDESED-------ENRGLRISYMGENVAEAVED-EKQISKQEVNKRI----LDLLETEKNSDEILWSYAKESEVLITKHRLAHYEFAKIRECEIKQSGSFIPYDNKIVIKRKTSFSLHSEE-----NLPNYKYKTYVET----VVDKFTQEILNNNETIQP--IKKNSNTPKFTYHFDSNLFSFDFQPKLENHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPKELEQALIESGVPSTLWNQADIPALQAVNPFEITQLVRETEQKLGVMKNEL--DRNETTLPNNLDNMRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMAWLGIHVLPTEEISIIQETEPKDRIPGSTPYVKGKNEKGQTIWTQIRYGKLEEPQNPLLRYIVDPEEELKLMLDGYEELEKNIGYKFHDISYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDARQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSIVINRFVRIQEENGHSISEEYYLIGEEECEEAED-------------VEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYTIMKNEIEQFSTNVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKRMQN 1947
BLAST of endoribonuclease dcr-1 vs. nr
Match: gi|422398915|ref|NP_001116485.2| (endoribonuclease Dicer-1 [Apis mellifera] >gi|1032020640|ref|XP_016767546.1| PREDICTED: endoribonuclease Dicer-1 isoform X1 [Apis mellifera]) HSP 1 Score: 1334.7 bits (3453), Expect = 0.000e+0 Identity = 810/2028 (39.94%), Postives = 1160/2028 (57.20%), Query Frame = 0
Query: 26 TPLEPGVEAVRACVLADRVLLVSQPQAKTFLLPALVREVC------LHRAGV-AVICVRREKQMTLWAEYFQRVSHASVAEIDVEPPPPG-QHWSVG-VVMATPAKLRQSLEADQFQP--LGLLIIDDGHAHVGCPDLGAILDHAQVRHA--RVVTLTA---NPLHAQGPLGLYPSQIQALESFYPGRVEAMSEPLSLLRSIVAPQLALVEFAQRPEPRVEAENIEAVLLRRTDELLVFLGQHRHALEETYGEEFRDLLEDIPDPTVVPIELVRDYQSVVRDLGVWAAERAAILMAIKVDKLKTMEKYERQFLLLSCVHTEMLQLREICGHALDGVSEQDKLTHYVKPKMTRLVEILLQYKP---SHVGSDVTDDPNAPVAPK-----------------------KSHRPNKSAP-----FGSYNDPQALRGIVYLKNQFQTKTLFHYLKDLSRSMEQYSFLCPQYVLGSHVSDQALDPSPVGVAKKREEDALRKFRLKEVNVLLSSDCLEMGVDSVRCNLVVLFDSLPNSLKEFIHCKIKAKYPESIFVILATHESADETLRELDVIETVEKDLISRSSYQPKAAS----SDLFPGQAVTQSEILKTKSVELSLDKGLWCLNRYCSKLPSDTFTRLSP---IFHTSVEGS-GHLSGILLPINSPVKDPILGSIMPNPTWAKKSAALKVCQILYESQELDENLFPTGKDFLLKHVQPNLGPLTPASAQ----GSRAGPRKQRHYYYK-TASKYLKLEPV-APKCHVYALELVLQCPIPDDQNTRGRKLFLPERAEQSFGFLTSELLPASCPFPIYTRSGEVLVKVILLKEDLELDEEQRNQVKEFHHYTFSDVLRLEKYPMAFNLGRCEINTLIVPLKKVAESGPQIDWDFLRKVVKEFVHSKPKPKRYNVEEGEKFQFDRATFQDAVVMPWYRNQDQPQYFYVAEIYQHLSPKSDFPGQGFESFEKYYKSKYDITISDPDQPLLDVDHTSARLNFLTPRYVTRKGISLPTSSEETKRNKRENLEQKQILVPELCAIHPFRASLWRQMVALPCIFYRLNSLLNADALRVRIASEAKVGKVILDPRFQWEPMDFGWTLNDVLKTRTGVDSESAKVSHNPTKKLGSNANRTKSGPIPRDSMADITEIFDDDDQEEDGSTDNLGKLNDRLLNTLIEEDQKLK--QKSLEIGTWSNEMAAPDDPPPNEADNEMDSDEESLSDMFDPFEALPDNLTFLSNEILPNPKTATGKDWGTGIEQRHFRVGSPTFFRNPNINIPGLMDD---SDGLSCSDSDDDMEDDRHFVTEEDGTSKIEFRGNNMAEAIEDAAEEIKRREILEQFKNEELELIETHP----WVWEDTGQSEIMAGNPERATTNLKMFAVDKPLDFQINNPQSTPED---LSGPQEPGPVNDPELASRLSAKVKEKLLVLPTSTEKPPNTPVVKPGVIPRDSDRP-FG-------FSFDYQPDLATFPGPSPSLILQALTMSNANDAINLERLETIGDSFLKYAITSALFLAYPDTPEGRLSHLRSKQVSNFHLYHLGWEKNMGECMITTKFEPHDNWLPPGYYVPKGLEKALIESGIPSTQWNTATLPDVSKLG----------TEEEILSMIKDLTSDRPEQSNNKPEDMRSFVPYNLLTQQSIPDKSIADCVEALIGAYLIAGGKQGALGFMAWLGMDVDPMQNEEEIQVVSPLNK-----------------------------------SVVSEPERHLSHLLQGFEQFEHIIGYSFRDKSYLLQAFTHTSYYPNRLTDCYQRLEFLGDAVLDFLITRHLYEDPQKHSPGALTDLRSALVNNTIFAIMAVKFGFHKFLLHLSPGLQTICHRFVKIQSQKNFEFEDDFYLVGEGVGSLSTGIWNDDGSLSEVEDVEVPKALGDVFESVAGAVFLDSGLSLDTVWRIFYRMMGPDIKKFMSNIPKSPIRELLELEPETAKFTRPERLSDGRRVRVSVDVFGKGTFKGVGRNYRIAKCTAAKCALRAIRKRSN 1927
TP E VE A D ++ + + +TFL+ L++E L + G ++ + E + T+ A Y Q+++ V D + + + V++AT Q L + P + L+I+D+ H + L IL + R++ L N G LGL +I+ +E+ + VE S+ LS+LR P+ +VE+A+ + + IE +L + FL HR+ E Y EEF + ++ IPDPT P E+++D ++ LG W A+RAA + I +KLK YER +LLL+ + + ++R +C +A + +SE++K+ Y K+ RL++IL Y P H+ + N ++ K KS N P DP L G++++ F K LF+ L ++S E+ FL P Y + ++ D + + + +++E+ L++FR+ E N+L+S+ LE G+D +CN V+ +D P + + ++ CK +A+ P++++V+L + E + E + +L +EK L+ + S + +D++ + + +++ + + +NRYC+KLPSDTFTRL+P I +++ ++ + LPINSPVK + MPN A++ AAL++C L+ E+D+NL P GK+ + P P ++ +R G K+R YYYK TA P+ ++Y + LVL CP+P++QNTRGR+++ PE + FG +T + +P CPFPIYTRSGEV VK+ L K+ + L+E Q ++ F +YTF++VLRL++Y M F+ E + +IVP+K +S +DW+FL + K + P + E + F+FD + + DAV+MPWYR+QDQPQYFYVAEI +L+PKS FPG + +FE+YY KYDI I + DQPLLDVDHTSARLNFLTPRYV RKG++LPTSSEETKR KRENLEQKQILV ELCAIHPF ASLWRQ V LPCI YR+N+LL A+ +R ++A +G+ L+ F+W +DFGW+L +VLK SE K+ N +NA TK I +D ++ ++ +D E + +L N I E +++ + LEIGTWS++MA N +D +L ++ P N+T L NE +W R GSP + G D SDG +D+ D+ ED E+ +I + G N+AEA+ED ++I ++E+ ++ L+L+ET +W +SE++ + A FA + + + N P + + + ++ E K + +V + E N ++P I ++S+ P F FSFD+QP L PGPSPSLILQALTMSNAND INLERLETIGDSFLKYAIT+ L+ Y + EG+LSHLRSKQVSN +LY LG +K +GE MI TKFEPHDNWLPP YYVPK LE+ALIESG+PST WN A +P + + TE+++ M +L + NN ++MR F+PYNL+TQ SIPDKSIADCVEALIGAYLIA G +GAL FMAWLG+ V P + IQ P ++ + +PE L +L G+E+ E IGY F D SYLLQAFTH SY PNRLTDCYQRLEFLGDAVLD+LITRHLYED ++HSPGALTDLRSALVNNTIFA +AV+ GFHK+ HLSPGL + +RFV+IQ + +++YL+GE + VEVPKALGDVFES+AGA++LDSG+SLD VW ++Y +M +I++F +N+PKSPIRELLELEPETAKF +PE+L+DGRRVRV+VDVFGKG+FKG+GRNYRIAKCTAAKCAL+ +++ N
Sbjct: 15 TPREYQVELFYAAKDKDIIVCLGKNYEQTFLVIKLIQEFATNNRRLLSQGGKRSLYILTDEDKCTIKASYIQQLTDLKVLLCDTCSTAEFIEKFEISHVLLATSKTCAQLLADKKILPHQINLVIVDECHKSINNSQLKFILQTILSCNNVPRIIGLAVPLFNLTQEPGRLGL---EIEKVENTFQCEVETASDILSILRYSPKPKEYVVEYAKSEKGELHI-TIENHILHAIE----FLRDHRYDPTEIYNEEFYEDIQKIPDPTEKPFEMMQDLLHILETLGPWCADRAAFALLILTEKLKIKTPYERHYLLLNMIASVFTKIRALCDNAFEVLSEKEKIYKYTTTKVHRLLQILKTYTPYYTKHINNTDNKINNENISRKFPANNRDSIKDKFMQSKKLDCNWKSSEENCKKPPVARHMRGITDPDLLCGVIFVDKAFVAKVLFYLLNEISMHDEELHFLSPLYTIEKNIDDISYSKD-LEIEHRKQEEVLKRFRIHECNILISTSILEEGIDIPKCNFVMRYD-FPKTYQSYVQCKSRARAPDALYVLLVSQEMSKEYVWQLAQYHYIEKTLLVKCSNNEPSEEEENEADMYAAMIPHYKPLDGGDAPKVTFNSAISLVNRYCAKLPSDTFTRLTPEWSIQEMNIDNILMYICSLRLPINSPVKYIVSSYPMPNKAMARRMAALQLCIDLHRKNEIDDNLLPIGKENFKAKPEDAEVPALPDESKVDFSEARPGTTKRRQYYYKKTAEALTDCRPIIGVPSYLYHINLVLSCPLPEEQNTRGRRIYPPEESAIGFGIITLKEIPKLCPFPIYTRSGEVHVKLKLTKQTIILNEMQVEKIATFLNYTFTNVLRLQQYLMLFDPNASENSYMIVPVKLDEQSDIAVDWNFLECIYK---NRNIGPTKIPEEARKNFKFDASKYHDAVIMPWYRSQDQPQYFYVAEICTNLNPKSSFPGNDYGTFEEYYLKKYDIQIQNLDQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVAELCAIHPFPASLWRQAVCLPCILYRINALLLANQIRCQVAQMINLGQENLNSDFEWPALDFGWSLAEVLKKSKE--SEKTKLIRNELN--STNAIDTKCQNISKDITENLYKLDKEDLNESNYEF--------QLTNDKITEAEQISNDENELEIGTWSSDMAM----------NSLDFGANNL-------KSFPLNVTVLPNEF----------NWN------DIRYGSPAC----ESDFDGYESDDIYSDGF--ADTSDESED-------ENRGLRISYMGENVAEAVED-EKQISKQEVNKRI----LDLLETEKNSDEILWSYAKESEVLITKHKLAHYE---FAKIRECEIK-QNGSFIPYNNKIVIKRKTSFSLHSEENLPNYKYKTYVETVVDKFTQEILNNNETIQP--IKKNSNTPKFTYHFDSNLFSFDFQPKLENHPGPSPSLILQALTMSNANDGINLERLETIGDSFLKYAITTYLYCTYDNIHEGKLSHLRSKQVSNLNLYRLGRQKMLGESMIATKFEPHDNWLPPCYYVPKELEQALIESGVPSTLWNQADIPALQAVNPFEITQLVRETEQKLGVMKNELDRNETTLPNNL-DNMRCFIPYNLITQHSIPDKSIADCVEALIGAYLIACGPRGALLFMAWLGIHVLPTEEINIIQETEPKDRIPGSTPFVKGKNEKGETIWTQIRYGKLEEPQNPLLRYIVDPEEELKLMLDGYEELEKNIGYKFHDISYLLQAFTHASYQPNRLTDCYQRLEFLGDAVLDYLITRHLYEDTRQHSPGALTDLRSALVNNTIFASLAVRCGFHKYFRHLSPGLSIVINRFVRIQEENGHSISEEYYLIGEEECEEAED-------------VEVPKALGDVFESLAGAIYLDSGMSLDAVWSVYYAIMKNEIEQFSTNVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFGKGSFKGIGRNYRIAKCTAAKCALKKLKRMQN 1946 The following BLAST results are available for this feature:
BLAST of endoribonuclease dcr-1 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 5
BLAST of endoribonuclease dcr-1 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of endoribonuclease dcr-1 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold117_size339417:236207..241990+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>snap_masked-scaffold117_size339417-processed-gene-2.5 ID=snap_masked-scaffold117_size339417-processed-gene-2.5|Name=endoribonuclease dcr-1|organism=Tigriopus kingsejongensis|type=gene|length=5784bp|location=Sequence derived from alignment at scaffold117_size339417:236207..241990+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'endoribonuclease dcr-1' has the following synonyms
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