alpha-ketoglutarate partial, snap_masked-scaffold6640_size3701-processed-gene-0.0 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of alpha-ketoglutarate partial vs. L. salmonis genes
Match: EMLSAG00000009098 (supercontig:LSalAtl2s:LSalAtl2s572:252815:272447:1 gene:EMLSAG00000009098 transcript:EMLSAT00000009098 description:"maker-LSalAtl2s572-augustus-gene-1.21") HSP 1 Score: 627.861 bits (1618), Expect = 0.000e+0 Identity = 352/895 (39.33%), Postives = 513/895 (57.32%), Query Frame = 0
Query: 262 QMAVSTLINQYRVRGHLIANTNPL--AETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEG-NPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLG--LKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGNY---PVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRES----------APPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETP---EGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETG-EEFTPLTEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAED-------------------NIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGT-FQEVLDDTN--APKAKSVRRVIFASGKVAAEAQAHRDEIGAP--AAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHR-IRRVSRTESGSPATGSLAVHKQEQQELLERAFA 1109
+ + I Y+VRGHL A+T+PL +++ +L + L DLD ++ IGG+ K + L +I+ L + YC SIG E+MHI + E WI++++E +S ++ +L R++ + E FLA ++ +KRFGLEG+E IP + ++ + + ++GM HRGRLNVL N K ++ +F G E++ +G GDVKYHLG ++ + + + N I + NPSHLE V PVV+G RA +Q G+ V+P+LLHGDAAFAGQGVV ET+++S + Y GTIH++ NNQ+G+TT P +SRSS Y TDV ++V PIFHVNADDPEA + V ++A YR +FHKDVV+D++GYR++GHNE D+P +TQP+MY I + ++ +Y LI G +S E + + ++ I + A + +P +G P T E L+ + S P E F +H + R + R +M +DWALGEA A G+LL +G VRL+GQD RGTF+HRH LH+ + + L + P+ + V +S+LSEY LGFE GY++ NP+ALV+WEAQFGDF N AQ IIDQF+ + + KW S L +LLPHG EG GPEHSS R ERFL LCA+D N+ V N +T +FH+LRRQ+ RKPL++ TPKS LR +S +D+ GT F+ ++ ++ + ++V+++IF +GKV + R E G A+ +EQ+ P+PF V + +KY NA+ +V QEE +N G W+ V+ R A G R I V R + SPATGS A+H +E + A +
Sbjct: 117 HLVLQATIRSYQVRGHLAAHTDPLNIKNMSTEAARKLIIRSADLANQDLDTVYILPPT----TWIGGKEKSLPLKEIIKRLENVYCGSIGAEFMHIHNLDEVNWIRKRLETPGILDMSVDEKKRLLARISRSAGFENFLAKKFTSEKRFGLEGVEMLIPGMKTIVDRSTELGVESVVMGMPHRGRLNVLANVCRKPLDQILTQFAGL--EAADEGXGDVKYHLGTYIERLNRATNKN-IRLAVVANPSHLEAVDPVVLGKVRA--EQFYRGDTEGKKVMPMLLHGDAAFAGQGVVYETMHMSDLPDYTTKGTIHIVANNQIGFTTDPRYSRSSPYCTDVGRVVNCPIFHVNADDPEAVISVCKIAAEYRHEFHKDVVVDIVGYRKYGHNEIDEPMFTQPIMYSIIKKHKNILDIYADQLIHEGIVSKEEVKEVIYKYEQICEDAYKKSNAQTEIYNKHWLXSPWSGFFEGKDPMKAS-----STGVHEETLENIGKKFSNGPPNAEDFKIHKSMIRILKARAQMVENRTIDWALGEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHNQDKDMSTYNALVHLYPDQAPYSVSNSSLSEYGVLGFELGYSMTNPNALVIWEAQFGDFSNTAQCIIDQFISSGQAKWVRQSGLVLLLPHGMEGMGPEHSSARPERFLQLCADDPEYFPPVDEDFTIRQLSHINMIVANCSTPGNYFHILRRQIALPFRKPLIIMTPKSLLRHPECKSSFDDMSLGTEFKRMIVESGLASENPQNVQKLIFCTGKVYYDLIKARKERGLEDRIAISTIEQISPFPFDIVKEECDKYSNAT-LVCCQEEHKNQGIWSYVQPRFQTAIGGYSRIINYVGREVAPSPATGSKAMHNKELNLFINDAMS 996
BLAST of alpha-ketoglutarate partial vs. L. salmonis genes
Match: EMLSAG00000008595 (supercontig:LSalAtl2s:LSalAtl2s52:665423:671019:1 gene:EMLSAG00000008595 transcript:EMLSAT00000008595 description:"snap_masked-LSalAtl2s52-processed-gene-6.12") HSP 1 Score: 476.863 bits (1226), Expect = 8.594e-154 Identity = 266/642 (41.43%), Postives = 380/642 (59.19%), Query Frame = 0
Query: 262 QMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEG-NPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLG--LKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARA--YMDQVEVGNYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRES-------------APPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETP---EGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEE--FTPLTEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFL 880
+ V + I Y+VRGHL A +PL G I D + + + + IGG+ K + L +I+ L + YC SIG E+MH+++ E WI++++E +++ ++ +L+R++ + E FLA ++ +KRFGLEG+E IP + ++ + + I+GM HRGRLNVL N K ++ +F G E+ +GSGDVKYHLG ++ + + + N + + NPSHLE V PVV G ARA + + GN V+ +LLHGDAAFAGQGVV ET+++S++ Y GTIH++ NNQ+G+TT P +SRSS Y TDV ++V +PIFHVNADDPEA + V +LA YR FHKDVVID++GYRRHGHNE D+P +TQP+MY I + +V LY++ LI+ G S E + +D + I + +A +ES +P +G P G T E L + S P + F VH + R + R +M +DWALGEA A G+LL +G V L+GQD RGTF+HRH LH ++T ++ + PL + P+ + V +S+LSEY LGFE GY++ NP+ALV+WEAQFGDF NGAQ IIDQFL
Sbjct: 130 HLVVHSTIRSYQVRGHLAAQIDPLNLINMTRDEAQRLIIRGTDISDQNMDKIYQLPHTTW--IGGKEKHLPLREIIMRLENVYCGSIGAEFMHLSNLDEVNWIRKRLETPGSMAVNVDEKKLILQRISRSAGFENFLAKKFTSEKRFGLEGVEMLIPGMKTIVDRSTELGVESIIMGMPHRGRLNVLANVCRKPLVQILTQFGGL--EAXDEGSGDVKYHLGTYIERLNRATNKN-MRLAVVANPSHLEAVDPVVQGKARAEQFYRGDQEGN-KVMSLLLHGDAAFAGQGVVYETMHMSELPDYTTKGTIHIVANNQIGFTTDPRYSRSSPYCTDVGRVVNSPIFHVNADDPEAXIFVCKLAAEYRHTFHKDVVIDMVGYRRHGHNEIDEPMFTQPIMYSIIKKHINVLDLYSKKLIEEGIFSKDEVKGLIDKYDQICE---EAYKESQLETQIYHTDWLXSPWSGFFEGKDPLKAG-----PTGVHEETLAHIGRRFSSGPPNADSFQVHKAMTRILKSRSEMVNNRTIDWALGEALAFGSLLKEGIHVXLSGQDVERGTFSHRHHILH-HQTKDKSTYNPLANLYPDQAPYTVCNSSLSEYGVLGFELGYSMTNPNALVLWEAQFGDFCNGAQCIIDQFL 756
BLAST of alpha-ketoglutarate partial vs. L. salmonis genes
Match: EMLSAG00000002721 (supercontig:LSalAtl2s:LSalAtl2s1574:42442:46748:1 gene:EMLSAG00000002721 transcript:EMLSAT00000002721 description:"maker-LSalAtl2s1574-augustus-gene-0.24") HSP 1 Score: 328.561 bits (841), Expect = 6.426e-98 Identity = 260/892 (29.15%), Postives = 394/892 (44.17%), Query Frame = 0
Query: 243 WLDDHGATEADDTEGLHAKQMA---VSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQM-ALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEG-NPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGNYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAK--------PSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQ-FEQRDKMFAEGE-VDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAE-------DNI--QVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGT-FQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIG-APAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
++DD +E + AK+ A V ++ +R GH A+ NPL + S ++PA++GL +G Y G K + +L DI L++ YC IGIE E W ++ E ++ ++ + L +E ++FLA ++ KR+G EG ES + L+ + D I+GM HRGRLN+L + Y G + S I+G+ ++ S L G V+ +A + Q E G + +L P +L V G T QLG+ YS++ +M + I + VR +LA Y++ F KDV ID++ YR+ GHNE DDP++T P +Y KI ++ SV +Y LI+ ++ SA F D+ + + P + K P+ + DT + + L + A + FT+HP L + + R K +GE +DW EA +IG+LL QG +VR++GQD R TF+HRH L D +T + PL E+ + + + T S Y + + + E KW S +T+LLPHG +G GPEHSS RLERFL + DN+ +V T +AQ+FHLLRRQ++R+ RKPLVV PK LR + S ++ + GT F V+DD + + ++VIF SGK +R A++R+EQL P+P + ++KY A +W QEE NMGAW V R G + V R+E PA G HK+E +L+ F
Sbjct: 27 YIDDDKKCFEFMSEQVQAKRSANPNVYRFVDAFRKHGHRFASINPLEDPKSLDKSIINPASYGLG-------------EGHYDVNGIIEKSINSLKDIHQYLKNVYCGKIGIEVFSPESEYESIWFFKRYEQLMEEDMASNEKTKLAMELLKSELFDQFLALKFANLKRYGGEGAESMMGFFLQLIKSSTDYEIEDIIVGMPHRGRLNLLTGLLNFPYS-------GVI--SKIKGNRELS-------------------------SELSGAGDVLSHLAITSVIQSENGKSTEVTLL-------------PNPSHLEAVNPVACGKTRAKHLLKQLGH-----------YSSNRERMGEKSICVLEV------VRATKLAVEYQRTFRKDVFIDILCYRKWGHNELDDPTFTNPDLYGKINKKISVPNMYLNKLIEENILTEESISSAKQKFNDLFVSEFNNSDSYEPSKAVFVKEWSNLQEAPNEQTIW-----DTGVSHDVLKYIGAKSVSFEDDFTIHPHLEKHHVKNRIKRLEKGEGIDWGTAEALSIGSLLYQGFNVRISGQDVGRATFSHRHGMLVDQDTNGIYIPLNELNLK----YNTERTFSSYNSXXXXXXXXXXXXXXVYCQKR------------------PGESKWGIPSGMTLLLPHGMDGAGPEHSSSRLERFLQMSDSKESEVDGDNVNWHIVYPTNSAQYFHLLRRQMVRNFRKPLVVAVPKICLRMSDAMSDLKSMQPGTKFNPVIDDLFS-NVEQTKKVIFVSGKHYYALNNYRKSRNIQDTALIRIEQLCPFPSKLLQDVVDKYSKAESFIWSQEEHRNMGAWTFVSPRFQNIVGVN--LSYVGRSELCQPAVGVSNKHKEESDYILKATF 811
BLAST of alpha-ketoglutarate partial vs. L. salmonis genes
Match: EMLSAG00000003975 (supercontig:LSalAtl2s:LSalAtl2s213:192560:194748:1 gene:EMLSAG00000003975 transcript:EMLSAT00000003975 description:"maker-LSalAtl2s213-augustus-gene-2.15") HSP 1 Score: 80.1073 bits (196), Expect = 9.317e-16 Identity = 59/209 (28.23%), Postives = 106/209 (50.72%), Query Frame = 0
Query: 11 TSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGV-GRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHE 218
T+F E+ L RK + ++ G K+ F A A+ P +N+V +EG++ ++ +++ +AV K L+VPV++N MN+A+ AL K ++N++ ++DM G T +++N G G++ P + P Q AI+G+ G + P Q+ + ++ + TYDHR+I G E+ +FLK V +
Sbjct: 261 TTFNELDMSALMQLRKENQDAFIKRHGFKLGFMSAFVKASAYALCQQ-PTVNAV-IEGNE----IIYRDYVDVSVAVATPKG-----LVVPVLRNVQDMNYADIEKGIAALGDKAKNNQIAMEDMEGGTFTISNGGVFGSLFGXPIINPPQSAILGMHGSFERPVVRN-------GQIVIRPMMYIALTYDHRLIDGREAVTFLKTVKK 451
BLAST of alpha-ketoglutarate partial vs. L. salmonis genes
Match: EMLSAG00000000594 (supercontig:LSalAtl2s:LSalAtl2s109:319455:320912:-1 gene:EMLSAG00000000594 transcript:EMLSAT00000000594 description:"augustus_masked-LSalAtl2s109-processed-gene-3.6") HSP 1 Score: 66.6254 bits (161), Expect = 2.088e-11 Identity = 42/139 (30.22%), Postives = 70/139 (50.36%), Query Frame = 0
Query: 82 NLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELL 220
N+G+A+D L+VP +KN A++ E A L KL+ +D+ G T +++N+G++G P + PGQ I +G I F+ DK V A ++N++ + DHRII GA F + +++
Sbjct: 346 NIGIAMDTPNG-----LLVPNVKNVQALSILEIGAELNRLQDLGVKGKLSSNDLNGGTFTISNIGSIGGTYMKPVITPGQVIIGAIGAIKAVPKFDKDDKIVKAS-----IMNISWSADHRIIDGATVARFSNSMKDMI 474
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|122976640|sp|Q1B4V6.1|KGD_MYCSS (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase >gi|160395551|sp|A1UK81.1|KGD_MYCSK RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1111.67 bits (2874), Expect = 0.000e+0 Identity = 575/1134 (50.71%), Postives = 759/1134 (66.93%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDL--HPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGN----YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATR-----ESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPL------TEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLD-----DTNAPKAKSVRRVIFASGKVAAEAQAHRD-EIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHR-IRRVSRTESGSPATGSLAVHKQEQQELLERAFA 1109
M +SL VPTATS R IPAKL+ NR V+NNHL R RGGK+SFTH++GYAIV A+ PNMN + E DGKP V NLGLA+D Q DG R L+V IK A M F +F+AAYE ++++ RD KLT +D +G TISLTN GT+GTV SVPRLM GQGAIIGVG ++YP F+ A ++ IA LG+ K++ +TSTYDHRIIQGAESG FL+ VH+LL+ +D+F+D +F+++G+PY V+W D+ + + K V LI YR RGHL+A+ +PL ++ HP+LD T GLT+WDLDR F V G + K+ L D+L VLRDAYCR IG+EY HI +P +++W+QE++EG + QQ ++L RL AAEA E FL +YVGQKRF LEG E+ IP +DA++ + A++ + ++GM HRGRLNVL N +GK Y ++F EFEG +N S GSGDVKYHLG GT+ G N I L NPSHLE V PV+ G+ RA D ++ G+ Y V+P++LHGDAAFAGQGVV ETLNL+ ++GY+ GGTIH+I NNQ+G+TT+P ++SSEY TDVAKM+ APIFHVN DDPEA V V+ LA +RQ+F KDVVIDL+ YRR GHNEGDDPS TQP MY I + VR YT+ LI RGDIS+ EAE A+ +Q L+ + R E P + A PA + TA + L R+ PEGFTVHP++ E+R +M EG+VDWA E A+GT++ +G+ VRL+GQD+RRGTF RH+ + D +TG+EFTPL ++ P G +F VYDS LSE+AA+GFEYGY++ NPDA+V+WEAQFGDF+NGAQ IID+F+ + E KW S + +LLPHG+EGQGP+H+SGR+ERFL L AE ++ + +T A +FHLLRR + +++PL+VFTPKS LR K + S + D E F+ VL+ D + + K V R++ SGK+ E A ++ E A+VR+EQL P P +A+ L+KY N E W+QEEP N GAW L E + I+R+SR +P++GS VH EQQE+L+ AFA
Sbjct: 159 MSASLDVPTATSVRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLIGYAIVAAVK-KFPNMNRHFAE-VDGKPNAVTPAHTNLGLAIDLQGKDGNRQLVVAAIKKADTMRFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMRGQGAIIGVGAMEYPAEFQGASEERIADLGIGKLITLTSTYDHRIIQGAESGDFLRTVHQLLL-SDDFFDEIFRELGIPYEPVRW-------RTDNPDSIEDKNARVIELIAAYRNRGHLMADIDPLRLDSNRFRSHPDLDVLTHGLTLWDLDREF------KVNGFAGAERKK--LRDVLAVLRDAYCRHIGVEYTHILEPEQQQWLQERIEGKHEKPTVAQQKYILSRLNAAEAFETFLQTKYVGQKRFSLEGAETVIPAMDAVIDQCAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGSSGTYLQMFGDNDITVSLTANPSHLEAVDPVMEGLVRAKQDLLDKGDTEDGYTVVPLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHLIVNNQIGFTTSPAAAKSSEYCTDVAKMIGAPIFHVNGDDPEAAVWVSRLAVDFRQKFKKDVVIDLLCYRRRGHNEGDDPSMTQPSMYDVIDTKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLEQVFNEVRELEKHEIEPSESVEADQQIPA-----KLATAVDKSLLARIGDAHLAVPEGFTVHPRVKPVLEKRREMAYEGKVDWAFAELLALGTMISEGKLVRLSGQDTRRGTFTQRHSVVIDRKTGKEFTPLQLLATDSDGNPTGGKFLVYDSPLSEFAAVGFEYGYSVGNPDAMVLWEAQFGDFINGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIALPSTPANYFHLLRRHSLDGIQRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSVLEEPTYTDGDGDRNK-VTRILLTSGKIYYELVARKNKESRDDVAIVRIEQLAPLPKRRLAETLDKYPNVEEKFWVQEEPANQGAWPTFGLTLPEMLPDHFTGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAFA 1268
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|160395550|sp|A3Q3N5.1|KGD_MYCSJ (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1111.67 bits (2874), Expect = 0.000e+0 Identity = 575/1134 (50.71%), Postives = 759/1134 (66.93%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDL--HPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGN----YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATR-----ESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPL------TEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLD-----DTNAPKAKSVRRVIFASGKVAAEAQAHRD-EIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHR-IRRVSRTESGSPATGSLAVHKQEQQELLERAFA 1109
M +SL VPTATS R IPAKL+ NR V+NNHL R RGGK+SFTH++GYAIV A+ PNMN + E DGKP V NLGLA+D Q DG R L+V IK A M F +F+AAYE ++++ RD KLT +D +G TISLTN GT+GTV SVPRLM GQGAIIGVG ++YP F+ A ++ IA LG+ K++ +TSTYDHRIIQGAESG FL+ VH+LL+ +D+F+D +F+++G+PY V+W D+ + + K V LI YR RGHL+A+ +PL ++ HP+LD T GLT+WDLDR F V G + K+ L D+L VLRDAYCR IG+EY HI +P +++W+QE++EG + QQ ++L RL AAEA E FL +YVGQKRF LEG E+ IP +DA++ + A++ + ++GM HRGRLNVL N +GK Y ++F EFEG +N S GSGDVKYHLG GT+ G N I L NPSHLE V PV+ G+ RA D ++ G+ Y V+P++LHGDAAFAGQGVV ETLNL+ ++GY+ GGTIH+I NNQ+G+TT+P ++SSEY TDVAKM+ APIFHVN DDPEA V V+ LA +RQ+F KDVVIDL+ YRR GHNEGDDPS TQP MY I + VR YT+ LI RGDIS+ EAE A+ +Q L+ + R E P + A PA + TA + L R+ PEGFTVHP++ E+R +M EG+VDWA E A+GT++ +G+ VRL+GQD+RRGTF RH+ + D +TG+EFTPL ++ P G +F VYDS LSE+AA+GFEYGY++ NPDA+V+WEAQFGDF+NGAQ IID+F+ + E KW S + +LLPHG+EGQGP+H+SGR+ERFL L AE ++ + +T A +FHLLRR + +++PL+VFTPKS LR K + S + D E F+ VL+ D + + K V R++ SGK+ E A ++ E A+VR+EQL P P +A+ L+KY N E W+QEEP N GAW L E + I+R+SR +P++GS VH EQQE+L+ AFA
Sbjct: 154 MSASLDVPTATSVRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLIGYAIVAAVK-KFPNMNRHFAE-VDGKPNAVTPAHTNLGLAIDLQGKDGNRQLVVAAIKKADTMRFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMRGQGAIIGVGAMEYPAEFQGASEERIADLGIGKLITLTSTYDHRIIQGAESGDFLRTVHQLLL-SDDFFDEIFRELGIPYEPVRW-------RTDNPDSIEDKNARVIELIAAYRNRGHLMADIDPLRLDSNRFRSHPDLDVLTHGLTLWDLDREF------KVNGFAGAERKK--LRDVLAVLRDAYCRHIGVEYTHILEPEQQQWLQERIEGKHEKPTVAQQKYILSRLNAAEAFETFLQTKYVGQKRFSLEGAETVIPAMDAVIDQCAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGSSGTYLQMFGDNDITVSLTANPSHLEAVDPVMEGLVRAKQDLLDKGDTEDGYTVVPLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHLIVNNQIGFTTSPAAAKSSEYCTDVAKMIGAPIFHVNGDDPEAAVWVSRLAVDFRQKFKKDVVIDLLCYRRRGHNEGDDPSMTQPSMYDVIDTKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLEQVFNEVRELEKHEIEPSESVEADQQIPA-----KLATAVDKSLLARIGDAHLAVPEGFTVHPRVKPVLEKRREMAYEGKVDWAFAELLALGTMISEGKLVRLSGQDTRRGTFTQRHSVVIDRKTGKEFTPLQLLATDSDGNPTGGKFLVYDSPLSEFAAVGFEYGYSVGNPDAMVLWEAQFGDFINGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIALPSTPANYFHLLRRHSLDGIQRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSVLEEPTYTDGDGDRNK-VTRILLTSGKIYYELVARKNKESRDDVAIVRIEQLAPLPKRRLAETLDKYPNVDEKFWVQEEPANQGAWPTFGLTLPEMLPDHFTGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAFA 1263
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|160395561|sp|Q7U0A6.2|KGD_MYCBO (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase >gi|160395562|sp|A1KI36.2|KGD_MYCBP RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1104.74 bits (2856), Expect = 0.000e+0 Identity = 572/1136 (50.35%), Postives = 759/1136 (66.81%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDL--HPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGN--------YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPH-IDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPL------TEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKA----KSVRRVIFASGKV-----AAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYE-AHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
M +SL VPTATS R +PAKLL NR V+NN L R RGGK+SFTH++GYA+V+A+ PNMN Y E DGKP V NLGLA+D Q DG R+L+V IK M FA+FV AYE ++++ RD KLT +D G TISLTN GT+GTV SVPRLMPGQGAIIGVG ++YP F+ A ++ IA+LG+ K++ +TSTYDHRIIQGAESG FL+ +HELL+ +D F+D +F+++ +PY V+W D+ + + K V LI YR RGHL+A+T+PL + HP+L+ T GLT+WDLDR F DG G Q K+ L D+LG+LRDAYCR IG+EY HI DP +K W++++VE + QQ ++L +L AAEA E FL +YVGQKRF LEG ES IP++DA + + A++ + ++GM HRGRLNVL N +GK Y ++F EFEG +N S GSGDVKYHLG G + G N I+ L NPSHLE V PV+ G+ RA D ++ G+ + V+P++LHGDAAFAGQGVV ETLNL+ + GY+VGGTIH+I NNQ+G+TTAP +SRSSEY TDVAKM+ APIFHVN DDPEACV VA LA +RQ+F KDVVID++ YRR GHNEGDDPS T P MY + + R YT+ LI RGDIS+ EAE A+ +Q L+ + RE G+ S + ++P + TA + L R+ P GFT HP++ E+R +M EG++DWA GE A+G+L+ +G+ VRL+GQDSRRGTF+ RH+ L D TGEEFTPL ++ P G +F VYDS LSEYAA+GFEYGYT+ NPDA+V+WEAQFGDFVNGAQ IID+F+ + E KW S++ +LLPHG+EGQGP+H+S R+ERFL L AE ++ + +T + +FHLLRR + +++PL+VFTPKS LR K + S ++D E F+ VL++ V R++ SGK+ A +A+ +R+++ A+VR+EQL P P + + L++Y N E W+QEEP N GAW L E + I+R+SR +P++GS VH EQQE+L+ AF
Sbjct: 118 MSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVK-KFPNMNRHYTE-VDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTTEDFAGVTISLTNPGTIGTVHSVPRLMPGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHELLL-SDGFWDEVFRELSIPYLPVRW-------STDNPDSIVDKNARVMNLIAAYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKV---DGF---AGAQYKK--LRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVETKHVKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRE-LEKHGVQPSESVESDQMIPAGLATAVDKSLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAYEGKIDWAFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHSVLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDFTEIKFRSVLEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDL----AIVRLEQLAPLPRRRLRETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAF 1230
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|160395558|sp|A5U1U6.2|KGD_MYCTA (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase >gi|614088643|sp|P9WIS4.1|KGD_MYCTO RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase >gi|614088651|sp|P9WIS5.1|KGD_MYCTU RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1102.81 bits (2851), Expect = 0.000e+0 Identity = 571/1136 (50.26%), Postives = 759/1136 (66.81%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDL--HPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGN--------YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPH-IDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPL------TEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKA----KSVRRVIFASGKV-----AAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYE-AHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
M +SL VPTATS R +PAKLL NR V+NN L R RGGK+SFTH++GYA+V+A+ PNMN Y E DGKP V NLGLA+D Q DG R+L+V IK M FA+FV AYE ++++ RD KLT +D G TISLTN GT+GTV SVPRLMPGQGAIIGVG ++YP F+ A ++ IA+LG+ K++ +TSTYDHRIIQGAESG FL+ +HELL+ +D F+D +F+++ +PY V+W D+ + + K V LI YR RGHL+A+T+PL + HP+L+ T GLT+WDLDR F DG G Q K+ L D+LG+LRDAYCR IG+EY HI DP +K W++++VE + QQ ++L +L AAEA E FL +YVGQKRF LEG ES IP++DA + + A++ + ++GM HRGRLNVL N +GK Y ++F EFEG +N S GSGDVKYHLG G + G N I+ L NPSHLE V PV+ G+ RA D ++ G+ + V+P++LHGDAAFAGQGVV ETLNL+ + GY+VGGTIH+I NNQ+G+TTAP +SRSSEY TDVAKM+ APIFHVN DDPEACV VA LA +RQ+F KDVVID++ YRR GHNEGDDPS T P +Y + + R YT+ LI RGDIS+ EAE A+ +Q L+ + RE G+ S + ++P + TA + L R+ P GFT HP++ E+R +M EG++DWA GE A+G+L+ +G+ VRL+GQDSRRGTF+ RH+ L D TGEEFTPL ++ P G +F VYDS LSEYAA+GFEYGYT+ NPDA+V+WEAQFGDFVNGAQ IID+F+ + E KW S++ +LLPHG+EGQGP+H+S R+ERFL L AE ++ + +T + +FHLLRR + +++PL+VFTPKS LR K + S ++D E F+ VL++ V R++ SGK+ A +A+ +R+++ A+VR+EQL P P + + L++Y N E W+QEEP N GAW L E + I+R+SR +P++GS VH EQQE+L+ AF
Sbjct: 118 MSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVK-KFPNMNRHYTE-VDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTTEDFAGVTISLTNPGTIGTVHSVPRLMPGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHELLL-SDGFWDEVFRELSIPYLPVRW-------STDNPDSIVDKNARVMNLIAAYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKV---DGF---AGAQYKK--LRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVETKHVKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYVYDVVDTKRGARKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRE-LEKHGVQPSESVESDQMIPAGLATAVDKSLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAYEGKIDWAFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHSVLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDFTEIKFRSVLEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDL----AIVRLEQLAPLPRRRLRETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAF 1230
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|160395554|sp|A0PVU7.1|KGD_MYCUA (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1095.49 bits (2832), Expect = 0.000e+0 Identity = 563/1140 (49.39%), Postives = 754/1140 (66.14%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLA--ETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGN--------YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRE-----SAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPL------TEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKA----KSVRRVIFASGK-----VAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGET-HRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
M +SL VPTATS R +PAKLL NR V+NN L R RGGK+SFTH++GYA+V+A+ PNMN YL+ DGKP V NLGLA+D Q DG R L+V IK M FA+FV AYE ++++ RD KLT +D +G TISLTN GT+GTV SVPRLM GQGAIIGVG ++YP F+ A ++ IA+LG+ K++ +TSTYDHRIIQGAESG FL+ +H++L+ D F+D +F+++ +PY V+W D+ + + K + LI YR RGHL+A+ +PL +T HP+LD T GLT+WDLDR+F G G +A + M L D+L +LRD YCR +G+EY HI +P +++W+Q++VE + QQ +VL +L AAEA E FL +YVGQKRF LEG ES IP++DA + + A+ + ++GM HRGRLNVL N +GK Y ++F EFEG +N S GSGDVKYHLG G + G N I+ L NPSHLE V PV+ G+ RA D +E G + V+P++LHGDAAFAGQGVV ETLNL+ + GY+VGGTIH+I NNQ+G+TTAP +SRS+EY TDVAK + APIFHVN DDPEACV VA LA +RQ+F+KDV+ID++ YRR GHNEGDDPS T P MY + + VR YT+ LI RGDIS+ EAE A+ +Q L+ + RE + P + + PA + TA + L R+ P+GFT HP++ E+R +M EG++DWA E A+G+L+ +G+ VR +GQD+RRGTF+ RH+ + D T EEFTPL + P G +F VYDS LSEYAA+GFEYGYT+ NPDA+V+WEAQFGDFVNGAQ IID+F+ + E KW S++ +LLPHG+EGQGP+H+SGR+ERFL L AE ++ + +T + +FHLLRR + +++PL+VFTPKS LR K + S ++D E F+ VL++ V R++ SGK VA +A+ R+++ A+VRVEQL P P + + L++Y NA E W+QEEP N GAW L E E ++R+SR +P++GS VH EQQE+L+ AF
Sbjct: 124 MSASLDVPTATSVRAVPAKLLIDNRIVINNQLKRNRGGKISFTHLLGYALVQAVK-KFPNMNRHYLD-VDGKPNAVTPAHTNLGLAIDLQGKDGKRALVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMAGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHQMLLA-DEFWDEIFRELSIPYLPVRW-------RPDNPDSIVDKNARIIELIAAYRNRGHLMADIDPLRLDKTRFRSHPDLDVCTHGLTLWDLDRSFKVG---GCFAG----PQNMKLRDVLSILRDTYCRHVGVEYTHILEPEQQQWLQQRVEAKHVKPTVAQQKYVLSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEYGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLEHGETDTENQRAFSVVPMMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSTEYCTDVAKTIGAPIFHVNGDDPEACVWVARLAVDFRQRFNKDVIIDMLCYRRRGHNEGDDPSMTNPRMYDVVDTKRGVRKSYTEALIGRGDISIKEAEDALRDYQGQLEQVFNEVRELEKHGAQPSESVESDQMIPA-----GLATAVDKSLLARIGDAFLAVPDGFTTHPRVQPVLEKRREMAYEGKIDWAFAELLALGSLVAEGKLVRFSGQDTRRGTFSQRHSVIIDRHTREEFTPLQLLTTNKDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDGVGDRNLVNRILLTSGKIYYEMVARKAKDKREDV----AIVRVEQLAPLPRRRLRETLDRYPNAKEFFWVQEEPANQGAWPRFGLELPELLPEKLSGVKRISRRAMSAPSSGSSKVHAVEQQEILDTAF 1237
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|160395549|sp|A0R2B1.1|KGD_MYCS2 (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1095.11 bits (2831), Expect = 0.000e+0 Identity = 569/1139 (49.96%), Postives = 754/1139 (66.20%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLA--ETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGN------YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATR-----ESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVG------PEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLD-----DTNAPKAKSVRRVIFASGKV-----AAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHR-IRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
M +SL VPTATS R IPAKL+ NR V+NNHL R RGGK+SFTH++GYAIV+A+ PNMN + DGKP + NLGLA+D Q DG R+L+V IK M F +F+AAYE ++++ RD KLT +D +G TISLTN GTLGTV SVPRLM GQGAIIG G ++YP F+ A ++ IA LG+ K++ +TSTYDHRIIQGAESG FL+ +H+LL+ D+F+D +F+++G+PY V+W D+ + + K V LI YR RGHL+A+ +PL T HP+LD + GLT+WDLDR F DG G Q K+ L DIL VLRDAYCR +G+EY HI +P ++RWIQE+VE + +Q ++L +L AAEA E FL +YVGQKRF LEG E+ IP++DA++ + A++ + ++ M HRGRLNVL N +GK Y ++F EFEG +N S GSGDVKYHLG GT+ G N IE L NPSHLE V PV+ G+ RA D ++ G + V+P++LHGDAAFAGQGVV ETLNL+ ++GY+ GGTIH++ NNQ+G+TTAP SRSSEY TDVAKM+ APIFHVN DDPEAC VA LA +RQ F KDVVID++ YRR GHNEGDDPS TQP MY I + R YT+ LI RGDIS+ EAE A+ +Q L+ + R E P + A P+ + TA + L R+ PEGFTVHP++ E+R +M EG +DWA E A+G+L+ +G+ VRL+GQD++RGTF RHA + D +TGEEFTPL + P G +F VY+S LSE+AA+GFEYGY++ NPDA+V+WEAQFGDFVNGAQ IID+F+ + E KW S + +LLPHG+EGQGP+H+SGR+ERFL L AE ++ + +T A +FHLLRR +++PL+VFTPKS LR K + S + D E F+ VL+ D + K V R++ SGK+ A +A+ +R+++ A+VR+EQL P P +A+ L++Y N E W+QEEP N GAW + L E + ++R+SR +P++GS VH EQQE+L+ AF
Sbjct: 116 MNASLEVPTATSVRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLLGYAIVQAVK-KFPNMNR-HFAVVDGKPTAITPAHTNLGLAIDLQGKDGNRSLVVAAIKRCETMRFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTNPGTLGTVHSVPRLMQGQGAIIGAGAMEYPAEFQGASEERIADLGIGKLITLTSTYDHRIIQGAESGDFLRTIHQLLL-DDDFFDEIFRELGIPYEPVRW-------RTDNPDSIEDKNARVIELIAAYRNRGHLMADIDPLRLDNTRFRSHPDLDVNSHGLTLWDLDREFKV---DGF---AGVQRKK--LRDILSVLRDAYCRHVGVEYTHILEPEQQRWIQERVETKHDKPTVAEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIPMMDAVIDQCAEHGLDEVVIAMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGATGTYIQMFGDNDIEVSLTANPSHLEAVDPVLEGLVRAKQDLLDTGEEGSDNRFSVVPLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIVVNNQIGFTTAPTDSRSSEYCTDVAKMIGAPIFHVNGDDPEACAWVARLAVDFRQAFKKDVVIDMLCYRRRGHNEGDDPSMTQPYMYDVIDTKRGSRKAYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHEIEPSESVEADQQIPS-----KLATAVDKAMLQRIGDAHLALPEGFTVHPRVRPVLEKRREMAYEGRIDWAFAELLALGSLIAEGKLVRLSGQDTQRGTFTQRHAVIVDRKTGEEFTPLQLLATNPDGTPTGGKFLVYNSALSEFAAVGFEYGYSVGNPDAMVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPANYFHLLRRHGKDGIQRPLIVFTPKSMLRNKAAVSDIRDFTESKFRSVLEEPMYTDGEGDRNK-VTRLLLTSGKIYYELAARKAKENREDV----AIVRIEQLAPLPRRRLAETLDRYPNVKEKFWVQEEPANQGAWPSFGLTLPEILPDHFTGLKRISRRAMSAPSSGSSKVHAVEQQEILDTAF 1226
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|160395557|sp|A1TDK2.2|KGD_MYCVP (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1094.72 bits (2830), Expect = 0.000e+0 Identity = 564/1132 (49.82%), Postives = 754/1132 (66.61%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLA--ETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGNYP----VLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRE-----SAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPL------TEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKA----KSVRRVIFASGKVAAEAQAHRDEIGA-PAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGET-HRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
M +SL VPTATS R IPAK + NR V+NNHL R RGGK+SFTH++GYAIV+A+ PNMN + E DGKP V NLGLA+D DG R+L+V IKN M+F +F+AAYE ++++ RD KLT +D G TISLTN GT+GTV SVPRLM GQGAI+G G ++YP F+ A ++ IA+LG+ K++ +TSTYDHRIIQGAESG FL+ +H LL+ D FYD +F+++G+P+ V+W D+ + + K V LI YR RGHL+A+ +PL +T HP+LD T GLT+WDLDR F V G K+ L DILG+LRDAYCR IG+EY HI +P +++W+QE++E + +Q ++L +L AAEA E FL +YVGQKRF LEG E+ IP++DA + + A++ + ++GM HRGRLNVL N +GK Y ++F EFEG +N S GSGDVKYHLG GT+ G N I+ L NPSHLE V PV+ G+ RA D ++ GN P V+P++LHGDAAFAGQGVV ETLNL+ ++GY+ GGTIH+I NNQ+G+TT+P+ SRSSEY TDVAKM+ APIFHVN DDPEACV VA+LA +RQ+F KDVVID++ YRR GHNEGDDPS TQP MY I + VR YT+ LI RGDIS+ EAE A+ +Q L+ + RE AP + + + PA + TA + L R+ P+ F VHP++ E+R +M EG+VDWA E A+GT L +G+++R GQD+RRGTF RH+ + D +TG EFTPL ++ P G +F YDS LSE+AA+GFEYGY++ NP+ALV+WEAQFGDFVNGAQ IID+F+ + E KW S + +LLPHG+EGQGP+H+SGR+ERFLLL AE ++ + +T A +FHLLRR + + +PL+VFTPKS LR K + S ++D E F+ VL++ + +R++ SGK+ E A + + G A++R+EQL P P +A L++Y NA + W+QEEP N GAW + L E E I+R+SR +P++GS VH EQQE+++ AF
Sbjct: 134 MSASLDVPTATSVRAIPAKAMIDNRIVINNHLKRTRGGKISFTHLLGYAIVQAVK-KFPNMNRHFAE-IDGKPVAVTPAHTNLGLAIDLPGKDGKRSLVVAAIKNCETMHFGQFIAAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMKGQGAIVGAGAMEYPAEFQGASEERIAELGVGKLMTLTSTYDHRIIQGAESGDFLRTIHTLLL-DDEFYDEIFRELGIPHEPVRW-------RIDNPDSIEDKNARVIELIAAYRNRGHLMADIDPLRLDKTRFRSHPDLDVNTHGLTLWDLDREF------KVNGFAGKTHKK--LRDILGLLRDAYCRHIGVEYTHILEPEQQQWLQERIEVKHEKPTVAEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGANGTYIQMFGDNDIDVSLVANPSHLEAVDPVLEGLVRAKQDILDKGNGPDGFTVVPMMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIIVNNQIGFTTSPYDSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVAKLAVDFRQKFKKDVVIDMLCYRRRGHNEGDDPSMTQPTMYDVIDTKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHAIAPSSSVESDQMVPA-----GMSTAVDKSLLARIGDAHLGYPDDFNVHPRVKPVLEKRREMAYEGKVDWAFAELLALGTFLAEGKTIRFTGQDTRRGTFTQRHSVIIDRQTGREFTPLDLLTVDSDGNPTGGKFMAYDSALSEFAAVGFEYGYSVGNPNALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLLLWAEGSMTIAMPSTPANYFHLLRRHGLDGIHRPLIVFTPKSMLRNKAAVSDLKDFTEMKFRSVLEEPTYTEGTGDRSKAKRILLTSGKLYYELAARKSKEGRDDVAILRLEQLAPLPKRRLAATLDEYPNAEQYFWVQEEPANQGAWPTLGLTLPEVLPEKLAGIKRISRRAMSAPSSGSSKVHAVEQQEIIDEAF 1242
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|81413742|sp|Q73WX4.1|KGD_MYCPA (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1093.18 bits (2826), Expect = 0.000e+0 Identity = 569/1137 (50.04%), Postives = 753/1137 (66.23%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDL--HPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGN--------YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPH-IDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVG------PEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKA----KSVRRVIFASGK-----VAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHR-IRRVSRTESGSPATGSLAVHKQEQQELLERAFA 1109
M +SL VPTATS R IPAKLL NR V+NN L R RGGK+SFTH++GYA+V+AI PNMN Y E DGKP + NLGLA+D Q DG R+L+V IKN M FA+FV AYE ++++ RD KLT +D G TISLTN GT+GTV SVPRLM GQGAIIGVG ++YP F+ A ++ IA+LG+ K++ +TSTYDHRIIQGAESG FL+ +HE+L+ +D F+D +F+++ +PY ++W D+ + + K V LI YR RGHL+A+ +PL S HP+L+ GLT+WDLDR F V G + K+ L DILG+LRDAYCR IG+EY HI DP ++ W+Q++VE + +Q +L +L AAEA E FL +YVGQKRF LEG ES IP++DA + + A++ + ++GM HRGRLNVL N +GK Y ++F EFEG +N + GSGDVKYHLG G + G N I+ L NPSHLE V PV+ G+ RA D ++ G + V+P++LHGDAAFAGQGVV ETLNL+ + GY+VGGTIH+I NNQ+G+TTAP HSRSSEY TDVAKM+ APIFHVN DDPEAC VA+LA +RQ+F KDVVID++ YR+ GHNEGDDPS T P MY + + VR YT+ LI RGDIS+ EAE A+ +Q L+ + RE G+ S A +LP + TA + L R+ PEGFT HP++ E+R +M EG++DWA E A+G+L+ G+ VRL+GQD+RRGTF+ RH+ + D TGEEFTPL + P G +F VYDS LSEYAA+GFEYGYT+ NPDALV+WEAQFGDFVNGAQ IID+F+ + E KW S++ +LLPHG+EGQGP+H+S R+ERFL L AE ++ + +T + +FHLLRR + +++PL+VFTPKS LR K + S ++D E F+ VL++ V RV+ SGK VA + + +RD++ A+VR+EQL P P + + L++Y N E W+QEEP N GAW L E + ++R+SR +P++GS VH EQQE+++ AFA
Sbjct: 134 MSASLEVPTATSVRAIPAKLLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAIK-KFPNMNRHYAE-IDGKPTAITPAHTNLGLAIDLQGKDGKRSLVVAGIKNCETMRFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMLL-SDGFWDDIFRELSIPYLPIRW-------STDNPDSIVDKNARVMELIAAYRNRGHLMADIDPLRLDGSRFRSHPDLEILNHGLTLWDLDRVF------KVNGFAGAEYKK--LRDILGLLRDAYCRHIGVEYTHILDPEQQEWLQQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYHLGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGADDQGDEKAFSVVPMMLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIVNNQIGFTTAPEHSRSSEYCTDVAKMIGAPIFHVNGDDPEACAWVAKLAVDFRQKFKKDVVIDMLCYRKRGHNEGDDPSMTNPAMYDVVDIKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRE-LEKHGVGPSESVEADQMLPAGLATAVDKALLARIGDAFLALPEGFTAHPRVQPVLEKRREMAYEGKIDWAFAELLALGSLVAGGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGTPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIKRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDGIGDRGKVSRVLLTSGKLYYELVARKNKDNRDDV----AIVRIEQLAPLPKRRLGETLDRYPNVREYFWVQEEPANQGAWPRFGLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFA 1247
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|160395563|sp|Q9CC97.2|KGD_MYCLE (RecName: Full=Multifunctional 2-oxoglutarate metabolism enzyme; AltName: Full=2-hydroxy-3-oxoadipate synthase; Short=HOA synthase; Short=HOAS; AltName: Full=2-oxoglutarate carboxy-lyase; AltName: Full=2-oxoglutarate decarboxylase; AltName: Full=Alpha-ketoglutarate decarboxylase; Short=KG decarboxylase; Short=KGD; AltName: Full=Alpha-ketoglutarate-glyoxylate carboligase; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1085.09 bits (2805), Expect = 0.000e+0 Identity = 562/1134 (49.56%), Postives = 750/1134 (66.14%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLA--ETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSG-NVIETELAPNPSHLETVGPVVVGMARAYMDQVEV---GN----YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPH-IDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVG------PEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKA----KSVRRVIFASGKVAAEAQA-----HRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
M +SL VPTATS R +PAKL+ NR V+NN L R RGGK+SFTH++GYA+V+A+ PN+N Y E DGKP V NLGLA+D Q DG R+L+V IK + FA+FV AYE ++++ RD KLT +D G TISLTN GT+GTV SVPRLM GQGAIIGVG ++YP F+ A + IA+LG+ K++ +TSTYDHRIIQGAESG FL+ +HE+++ +D+F+D +F+++ +PY V+W D+ + + K V LI YR RGHL+A+ +PL T HP+LD T GLT+WDLDR F GG K L D+LG+LRDAYCR IG+EY HI DP ++ W+Q++VE + +Q ++L +L AAEA E FL +YVGQKRF LEG ES IP++DA + + A + + ++GM HRGRLNVL N +GK Y ++F EFEG +N + SGDVKYHLG G + G N I+ L NPSHLE V PV+ G+ RA D + GN + V+P++LHGDAAFAGQGVV ETLNL+ + GY+VGGTIH+I NNQ+G+TTAP +SRSSEY TDVAKM+ APIFHVN DDPEACV VA+LA +RQ+F KDVVID++ YRR GHNEGDDPS T P MY + + R YT+ LI RGDIS+ EAE A+ +Q L+ + R+ G+ S + ++P + TA + L R+ PEGFTVHP++ E+R +M EG++DWA E A+G+L+ +G+ VRL+GQD++RGTF+ RH+ + D TGEEFTPL + P G +F VY+S LSEYAA+GFEYGYT+ NPDA+V+WEAQFGDFVNGAQ IID+F+ + E KW S++ +LLPHG+EGQGP+H+SGR+ERFL L AE ++ +T + +FHLLRR + +++PL+VFTPKS LR K + S ++D E F+ VL++ + V RV+ GK+ E A +RD++ A+VR+EQL P P + + L++Y NA E W+QEEP N GAW L E I+R+SR +P++GS VH EQQE+L+ AF
Sbjct: 127 MSASLDVPTATSVRAVPAKLMIDNRTVINNQLKRNRGGKISFTHLLGYALVQAVK-KFPNINRHYAE-IDGKPIAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCEELRFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMTGQGAIIGVGAMEYPAEFQGASAERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMVL-SDSFWDEIFRELSIPYLPVRW-------RTDNPDSIVDKNARVMELIAAYRNRGHLMADIDPLRLDNTRFRSHPDLDLLTHGLTLWDLDRVFKVN-------GFGGW-KYKKLRDVLGLLRDAYCRHIGVEYTHILDPEQQEWLQQRVETKNVKPTVAEQKYILSKLNAAEAFETFLHTKYVGQKRFSLEGAESVIPMMDAAIDQCAKHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPTLAHSSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLNKDTNGNQDEAFSVVPMMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVAKLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISLKEAEDALRDYQGQLERVFNEVRD-LEKHGVQPSESVESDQMIPAGLSTAVDKALLARIGDAFLAVPEGFTVHPRVQPVLEKRREMAYEGKIDWAFAELLALGSLVAEGKLVRLSGQDTKRGTFSQRHSVIIDRHTGEEFTPLQLLANNPDGSPTGGKFLVYNSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFINSGEAKWGQLSTVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTFAVPSTPSNYFHLLRRHALDGIKRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDSIDDRSKVTRVLLTCGKLYYELAARKIKDNRDDV----AIVRIEQLAPLPRRRLGETLDRYENAKEFFWVQEEPANQGAWPRFGLELPELLPRLTGIKRISRRAMSAPSSGSSKVHAVEQQEILDTAF 1237
BLAST of alpha-ketoglutarate partial vs. SwissProt
Match: gi|425906051|sp|Q8NRC3.2|ODO12_CORGL (RecName: Full=2-oxoglutarate dehydrogenase E1/E2 component; Short=ODH E1/E2 component; Includes: RecName: Full=2-oxoglutarate dehydrogenase E1 component; Short=ODH E1 component; AltName: Full=Alpha-ketoglutarate dehydrogenase E1 component; Short=KDH E1 component; Includes: RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=2-oxoglutarate dehydrogenase complex E2 component; Short=ODH E2 component; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase) HSP 1 Score: 1031.94 bits (2667), Expect = 0.000e+0 Identity = 540/1127 (47.91%), Postives = 729/1127 (64.69%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDL----HPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGN-VIETELAPNPSHLETVGPVVVGMARAYMDQVEVG--NYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGV-----LPH-IDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEV----GPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGT-FQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIGA-PAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
M+ SL +PTATS R++PA+L+ NR ++N+ L R RGGK+SFTHI+GYA+V+A+ P+MN+ Y + DGKP ++ INLGLA+D + DG+R L+V IK MNF+EF+AAYE ++ + R KLT+DD G T+SLTN G +GT SVPRL GQG IIGVG +DYP F+ A + +A+LG+ K+V +TSTYDHR+IQGA SG FL+ + LL D+F+D +F + VPYT ++W D T D K V LI YR RGHLIA+TNPL+ + H +LD T LTIWDLDRTF G GG+ + M L ++L LR AY +G EY HI D E+ W+Q+++E ++ +Q ++L++L AAEA E FL +YVGQKRF LEG E+ IP++D+ + AA + ++GM HRGRLNVL N +GK +F EFEG + + I GSGDVKYHLG +G H G+ I+ L NPSHLE V PV+ G+ RA D ++ G V+P+LLHGDAAFAG G+VPET+NL++++GY VGGTIH++ NNQ+G+TT P SRS Y+TD AK P+FHVN DDPEA V V +LA YR++F KDV IDL+ YR GHNE DDPS TQP MY I R +VR YT++L+ RGD+S +AE+ + F D ++ + +E K + G+ LPH ++T +RE+L + + TPEGF HP++A ++R EG +DWA GE A G+L + GR VRLAG+DSRRGTF RHA D T EEF PL E+ G G +F VY+S L+EYA +GFEYGY++ N D++V WEAQFGDF NGAQ IID+++ + E KW S L +LLPHGYEGQGP+HSS R+ERFL LCAE ++ V +T A FHLLRR + D+++PLV+FTPKS LR K + S ED E T FQ V++D N A V++V+ SGK+ E +++ G A+VR+E L+P PF +++AL Y NA E++++Q+EP N G W + L E ++RRVSR S ATG VH+ E+++L++ AF
Sbjct: 118 MDISLEIPTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFTHIIGYAMVKAVM-AHPDMNNSY-DVIDGKPTLIVPEHINLGLAIDLPQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVARSRKGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGSMDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQGAVSGEFLRTMSRLLT-DDSFWDEIFDAMNVPYTPMRWAQDVPNTGVD-------KNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPDHRDLDIETHNLTIWDLDRTFNVG-------GFGGK-ETMTLREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQAEQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLTANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTTTPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQMESVFNEVKEGG------KKQAEAQTGITGSQKLPHGLETNISREELLELGQAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAWGELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEFNPLHELAQSKGNNG-KFLVYNSALTEYAGMGFEYGYSVGNEDSIVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPSTPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTEVTKFQSVINDPNVADAAKVKKVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDEPANQGPWPFYQEHLPELIPNMPKMRRVSRRAQSSTATGVAKVHQLEEKQLIDEAF 1219
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|918750722|ref|WP_052603785.1| (multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [Actinobacteria bacterium IMCC26207]) HSP 1 Score: 1480.31 bits (3831), Expect = 0.000e+0 Identity = 724/1114 (64.99%), Postives = 868/1114 (77.92%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQV---EVGNYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVG-PEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAP-KAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAFA 1109
M++SLGVPTATS+RE+PAKLLEVNR V+N +L R RGGKVSFTH++GYA+VRAIAD +P MN+ YLEG +G+PR+++ ++LG+A+D +K DG+R+L+VP I+NA M+FA+F A Y+ LI+K + NKLTV+D G T++LTN GT+GT +SVPRLMPGQG I+G G +DYPT F AD IA+LG+SKV+ ++STYDHRIIQGAESG LK++H+LL+G D+FY+ +F+ +GVPY AV+W D AD KQM VSTLIN +RVRGHLIA+ +PL+ ++H ELDPAT+GLTIWDLDR FLTG G+YA +GG K+ +LGD+L VLRDAYCR++GIE+MHI +PAEKRWIQEQVEG P + Q H+L RL AAEALEKFLA +Y+GQKRFGLEG ES IP+LDALL EAAD + A+LGM+HRGRLNVL N +GKSY +LF+EFEG V+ +SIQGSGDVKYHLG +GT + SG + LA NPSHLE V PVV GM RA MD + +PVLPIL+HGDAAFAGQGVV ETLNLS +KGY+VGGTIHVI NNQLG+TT P +RSSEY TD+AK VQAPI HVN DDPEACVRVA LAFAYRQ+FHKDVVID++ YRRHGHNEGDDPSYTQP+MYR I+ +VR Y + L+ RGD ++ EAE A+ FQ LQ ALD TR+SAP LA P PP GVLPH TAAT E+L+ VY ++S P F VH KLA+QF RD M G+VDWAL E+ A GTLL++G SVRLAGQDSRRGTF++RH+TL +ETG EFTPL ++ P T+ W+YDS LSEYAALGFEYGYT+ NPDALVMWEAQFGDF NGAQIIIDQ++VAAEDKW S L MLLPHGYEGQGPEHSS R+ERFL LCAEDNIQV TTAAQ+FHLLRRQV R VRKPL++ TPKSGLR K RS V L GTF+E+L D++A A SV R++ ASGKV EA RDE+G AV RVEQLYPWP+ VAK LE++ NA+EIVWLQEEPENMG WN VKG LYEA G+ IRRVSR + GSPATGS A+H+QEQ +L AFA
Sbjct: 101 MQASLGVPTATSYREVPAKLLEVNRSVINGYLGRTRGGKVSFTHLIGYALVRAIADHLPQMNAAYLEGPEGEPRIIRNAQVSLGIAIDMEKRDGSRSLVVPCIRNANEMDFAQFTAVYDDLIRKAKTNKLTVEDFAGVTVTLTNPGTIGTERSVPRLMPGQGTIVGAGSLDYPTGFAGADPHTIAELGISKVITLSSTYDHRIIQGAESGMMLKKIHDLLLGGDDFYEEIFRSVGVPYEAVRWRQD--VNPADHESSQIEKQMQVSTLINMHRVRGHLIADLDPLSAKLPEMHAELDPATYGLTIWDLDREFLTGGDVGIYAPVGGIRKR-SLGDLLHVLRDAYCRTVGIEFMHIQEPAEKRWIQEQVEGAPTKLPVDDQRHILGRLNAAEALEKFLATKYLGQKRFGLEGAESLIPILDALLEEAADQGLDSAVLGMSHRGRLNVLANIVGKSYSQLFREFEGYVDPASIQGSGDVKYHLGAEGTFVARSGVELPVGLAANPSHLEAVNPVVEGMTRARMDAIPHDRERRFPVLPILMHGDAAFAGQGVVAETLNLSLIKGYRVGGTIHVIVNNQLGFTTPPESARSSEYCTDIAKAVQAPIIHVNGDDPEACVRVARLAFAYRQRFHKDVVIDMVCYRRHGHNEGDDPSYTQPLMYRTISNLRNVRMRYVETLVRRGDFTLEEAEQALADFQGRLQTALDETRQSAPEEEYLASPHPPNKGVLPHAATAATAEELEAVYTVLSTAPPEFFVHTKLAKQFAARDAMLQAGQVDWALAESLAFGTLLNEGTSVRLAGQDSRRGTFSNRHSTLFCHETGAEFTPLAQLANPPHTQLWIYDSLLSEYAALGFEYGYTVQNPDALVMWEAQFGDFANGAQIIIDQYIVAAEDKWGQTSGLVMLLPHGYEGQGPEHSSSRIERFLTLCAEDNIQVCQPTTAAQYFHLLRRQVKRTVRKPLIITTPKSGLRDKRWRSSVGALTHGTFEELLGDSSADLDAASVTRLVLASGKVGQEAITRRDELGVHTAVARVEQLYPWPYEAVAKELERFPNATEIVWLQEEPENMGPWNFVKGHLYEALGDRFEIRRVSRADEGSPATGSHAIHEQEQDMILNAAFA 1211
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|829597424|gb|KLR59864.1| (2-oxoglutarate dehydrogenase, E1 component [Actinobacteria bacterium IMCC26207]) HSP 1 Score: 1479.54 bits (3829), Expect = 0.000e+0 Identity = 724/1114 (64.99%), Postives = 868/1114 (77.92%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQV---EVGNYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVG-PEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAP-KAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAFA 1109
M++SLGVPTATS+RE+PAKLLEVNR V+N +L R RGGKVSFTH++GYA+VRAIAD +P MN+ YLEG +G+PR+++ ++LG+A+D +K DG+R+L+VP I+NA M+FA+F A Y+ LI+K + NKLTV+D G T++LTN GT+GT +SVPRLMPGQG I+G G +DYPT F AD IA+LG+SKV+ ++STYDHRIIQGAESG LK++H+LL+G D+FY+ +F+ +GVPY AV+W D AD KQM VSTLIN +RVRGHLIA+ +PL+ ++H ELDPAT+GLTIWDLDR FLTG G+YA +GG K+ +LGD+L VLRDAYCR++GIE+MHI +PAEKRWIQEQVEG P + Q H+L RL AAEALEKFLA +Y+GQKRFGLEG ES IP+LDALL EAAD + A+LGM+HRGRLNVL N +GKSY +LF+EFEG V+ +SIQGSGDVKYHLG +GT + SG + LA NPSHLE V PVV GM RA MD + +PVLPIL+HGDAAFAGQGVV ETLNLS +KGY+VGGTIHVI NNQLG+TT P +RSSEY TD+AK VQAPI HVN DDPEACVRVA LAFAYRQ+FHKDVVID++ YRRHGHNEGDDPSYTQP+MYR I+ +VR Y + L+ RGD ++ EAE A+ FQ LQ ALD TR+SAP LA P PP GVLPH TAAT E+L+ VY ++S P F VH KLA+QF RD M G+VDWAL E+ A GTLL++G SVRLAGQDSRRGTF++RH+TL +ETG EFTPL ++ P T+ W+YDS LSEYAALGFEYGYT+ NPDALVMWEAQFGDF NGAQIIIDQ++VAAEDKW S L MLLPHGYEGQGPEHSS R+ERFL LCAEDNIQV TTAAQ+FHLLRRQV R VRKPL++ TPKSGLR K RS V L GTF+E+L D++A A SV R++ ASGKV EA RDE+G AV RVEQLYPWP+ VAK LE++ NA+EIVWLQEEPENMG WN VKG LYEA G+ IRRVSR + GSPATGS A+H+QEQ +L AFA
Sbjct: 120 MQASLGVPTATSYREVPAKLLEVNRSVINGYLGRTRGGKVSFTHLIGYALVRAIADHLPQMNAAYLEGPEGEPRIIRNAQVSLGIAIDMEKRDGSRSLVVPCIRNANEMDFAQFTAVYDDLIRKAKTNKLTVEDFAGVTVTLTNPGTIGTERSVPRLMPGQGTIVGAGSLDYPTGFAGADPHTIAELGISKVITLSSTYDHRIIQGAESGMMLKKIHDLLLGGDDFYEEIFRSVGVPYEAVRWRQD--VNPADHESSQIEKQMQVSTLINMHRVRGHLIADLDPLSAKLPEMHAELDPATYGLTIWDLDREFLTGGDVGIYAPVGGIRKR-SLGDLLHVLRDAYCRTVGIEFMHIQEPAEKRWIQEQVEGAPTKLPVDDQRHILGRLNAAEALEKFLATKYLGQKRFGLEGAESLIPILDALLEEAADQGLDSAVLGMSHRGRLNVLANIVGKSYSQLFREFEGYVDPASIQGSGDVKYHLGAEGTFVARSGVELPVGLAANPSHLEAVNPVVEGMTRARMDAIPHDRERRFPVLPILMHGDAAFAGQGVVAETLNLSLIKGYRVGGTIHVIVNNQLGFTTPPESARSSEYCTDIAKAVQAPIIHVNGDDPEACVRVARLAFAYRQRFHKDVVIDMVCYRRHGHNEGDDPSYTQPLMYRTISNLRNVRMRYVETLVRRGDFTLEEAEQALADFQGRLQTALDETRQSAPEEEYLASPHPPNKGVLPHAATAATAEELEAVYTVLSTAPPEFFVHTKLAKQFAARDAMLQAGQVDWALAESLAFGTLLNEGTSVRLAGQDSRRGTFSNRHSTLFCHETGAEFTPLAQLANPPHTQLWIYDSLLSEYAALGFEYGYTVQNPDALVMWEAQFGDFANGAQIIIDQYIVAAEDKWGQTSGLVMLLPHGYEGQGPEHSSSRIERFLTLCAEDNIQVCQPTTAAQYFHLLRRQVKRTVRKPLIITTPKSGLRDKRWRSSVGALTHGTFEELLGDSSADLDAASVTRLVLASGKVGQEAITRRDELGVHTAVARVEQLYPWPYEAVAKELERFPNATEIVWLQEEPENMGPWNFVKGHLYEALGDRFEIRRVSRADEGSPATGSHAIHEQEQDMILNAAFA 1230
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|521046150|ref|WP_020378174.1| (multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [Candidatus Microthrix parvicella]) HSP 1 Score: 1406.35 bits (3639), Expect = 0.000e+0 Identity = 683/1115 (61.26%), Postives = 856/1115 (76.77%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVE-GNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQV--EVGN-YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAP--PAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEA-HGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
ME+SLGVPTATS R++PAKLLEVNR V+N HL R RGGKVSFTHI+GYAIVRAIAD P+M + DGKP+V + I +GLA+D ++ G R L+VPVIK A +MNF EFV AY ++ + NKLTVDD GA +SLTN GT+GTV SVPRLM GQ I+GVG++ YPTA++ AD + IA LG+SKV+ +TSTYDHR+IQGAESGSFL+ V LL+G ++FY +F DIGVPY AV+W D + AD GL KQM+++ L+N YR RGHLIA +PLA ++H ELDP T+GLTIWDLDR F TG +YAS+GGQ + + L +IL VLR+AYCR+IG+E+MH+ + EKRWIQE++E G ++++ +Q H+L+ L A+ALE+FL +++GQKRFGLEG ES IP+LD +LT AA N+ + A+LGMAHRGRLNVLVN +GK Y +LF EFE ++E ++QGSGDVKYHLG +G +S +GNVI+ ELA NPSHLETV P+V+G+ARA MDQ+ V N YPVLPIL+HGDAAFAGQGVV ETLNLS +KGYK GGTIH++ NNQLG+TT P +RSSEY TDVAKMVQAPIFHVN +DPEACVRVA LA+ YR++F KDVVID++ YR+HGHNEGDDPSYTQP+MY++I VR LYT++L+ RG IS+ +AE A D + L AL++TRE+ P P + A P+P GV+ + T R +LDR++ ++ P FT+HPKLA+QF+ R KMF GEVDW+LGEA A G+LL +G VRLAGQDSRRGTF+ RHA L D+ TG+++ PL+ + +G+E W+YDS LSEYAALGFEYGY++ NPDALVMWEAQFGDFVNGA II+DQ+LVAAEDKWK S L MLLPHGYEGQGPEHSS R+ERFL+L AEDNIQ+ N T+AAQ+FHLLRRQ+ RD KPL++FTPKSGLRAK RS + +G F E+L D + ++V RV+ ASGKVA EA R+++ P AV RVEQL+PWPFA + L++Y N +EIVWLQEEPENMG WN +KGRLYEA G +IRRVSR SGSPATGS +H+QEQ E+L ++F
Sbjct: 116 MEASLGVPTATSVRDVPAKLLEVNRGVINGHLGRTRGGKVSFTHIIGYAIVRAIADHHPDMAVTFSRDDDGKPQVTRHSEIGMGLAIDVERR-GERLLMVPVIKGAQSMNFREFVDAYGDVVDRTMANKLTVDDFQGALVSLTNPGTIGTVLSVPRLMSGQSVIVGVGKLAYPTAYQGADPETIANLGISKVLTLTSTYDHRVIQGAESGSFLRTVERLLLGDEDFYRRIFADIGVPYVAVEWRQD--SNPADHLGGLIQKQMSIAMLVNMYRSRGHLIAELDPLAAKIPEIHEELDPVTYGLTIWDLDREFQTG-PGSIYASVGGQDR-LPLSEILRVLRNAYCRTIGVEFMHMQEVDEKRWIQEKMESGKTFTLTGDEQIHILDLLNKADALEQFLGTKFLGQKRFGLEGAESAIPILDEVLTLAAANHMDSAVLGMAHRGRLNVLVNIVGKRYQDLFGEFEQIIDEDAVQGSGDVKYHLGQRGQFKSVAGNVIDLELAANPSHLETVDPIVLGIARAKMDQIPKNVENKYPVLPILVHGDAAFAGQGVVAETLNLSSIKGYKAGGTIHLVINNQLGFTTPPESARSSEYPTDVAKMVQAPIFHVNGNDPEACVRVARLAYEYRREFGKDVVIDMVCYRKHGHNEGDDPSYTQPLMYQRIDNMAPVRELYTESLVGRGHISLEQAEKAADAYHAELTNALESTREAKPSEPRTVPAPPNPE--GVIGPVATGVDRTELDRIFEALNTVPADFTIHPKLAKQFDTRRKMFEAGEVDWSLGEALAFGSLLAEGTPVRLAGQDSRRGTFSQRHAALVDFHTGDDYLPLSALTTDGSELWIYDSLLSEYAALGFEYGYSVENPDALVMWEAQFGDFVNGASIIVDQYLVAAEDKWKQTSDLVMLLPHGYEGQGPEHSSARIERFLILAAEDNIQLCNVTSAAQYFHLLRRQIHRDGNKPLIIFTPKSGLRAKSYRSPISQFTDGHFCELLPDDSGLDPETVTRVVLASGKVAHEAIERRNQLNVPMAVARVEQLFPWPFAAIEAELDRYPNCNEIVWLQEEPENMGPWNGIKGRLYEAFEGRGMQIRRVSRVASGSPATGSSLIHRQEQDEILTKSF 1223
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|501180017|ref|WP_012223147.1| (multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [Candidatus Microthrix parvicella] >gi|499280189|emb|CCM62086.1| Oxoglutarate decarboxylase [Candidatus Microthrix parvicella RN1]) HSP 1 Score: 1405.58 bits (3637), Expect = 0.000e+0 Identity = 683/1115 (61.26%), Postives = 856/1115 (76.77%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVE-GNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQV--EVGN-YPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAP--PAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEA-HGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAF 1108
ME+SLGVPTATS R++PAKLLEVNR V+N HL R RGGKVSFTHI+GYAIVRAIAD P+M + DGKP+V + I +GLA+D ++ G R L+VPVIK A +MNF EFV AY ++ + NKLTVDD GA +SLTN GT+GTV SVPRLM GQ I+GVG++ YPTA++ AD + IA LG+SKV+ +TSTYDHR+IQGAESGSFL+ V LL+G ++FY +F DIGVPY AV+W D + AD GL KQM+++ L+N YR RGHLIA +PLA ++H ELDP T+GLTIWDLDR F TG +YAS+GGQ + + L +IL VLR+AYCR+IG+E+MH+ + EKRWIQE++E G ++++ +Q H+L+ L A+ALE+FL +++GQKRFGLEG ES IP+LD +LT AA N+ + A+LGMAHRGRLNVLVN +GK Y +LF EFE ++E ++QGSGDVKYHLG +G +S +GNVI+ ELA NPSHLETV P+V+G+ARA MDQ+ V N YPVLPIL+HGDAAFAGQGVV ETLNLS +KGYK GGTIH++ NNQLG+TT P +RSSEY TDVAKMVQAPIFHVN +DPEACVRVA LA+ YR++F KDVVID++ YR+HGHNEGDDPSYTQP+MY++I VR LYT++L+ RG IS+ +AE A D + L AL++TRE+ P P + A P+P GV+ + T R +LDR++ ++ P FT+HPKLA+QF+ R KMF GEVDW+LGEA A G+LL +G VRLAGQDSRRGTF+ RHA L D+ TG+++ PL+ + +G+E W+YDS LSEYAALGFEYGY++ NPDALVMWEAQFGDFVNGA II+DQ+LVAAEDKWK S L MLLPHGYEGQGPEHSS R+ERFL+L AEDNIQ+ N T+AAQ+FHLLRRQ+ RD KPL++FTPKSGLRAK RS + +G F E+L D + ++V RV+ ASGKVA EA R+++ P AV RVEQL+PWPFA + L++Y N +EIVWLQEEPENMG WN +KGRLYEA G +IRRVSR SGSPATGS +H+QEQ E+L ++F
Sbjct: 116 MEASLGVPTATSVRDVPAKLLEVNRGVINGHLGRTRGGKVSFTHIIGYAIVRAIADHHPDMAVTFSRDDDGKPQVTRHSEIGMGLAIDVERR-GERLLMVPVIKGAQSMNFREFVDAYGDVVDRTMANKLTVDDFQGALVSLTNPGTIGTVLSVPRLMSGQSVIVGVGKLAYPTAYQGADPETIANLGISKVLTLTSTYDHRVIQGAESGSFLRTVERLLLGEEDFYRRIFADIGVPYVAVEWRQD--SNPADHLGGLIQKQMSIAMLVNMYRSRGHLIAELDPLAAKIPEIHEELDPVTYGLTIWDLDREFQTG-PGSIYASVGGQDR-LPLSEILRVLRNAYCRTIGVEFMHMQEVDEKRWIQEKMESGKTFTLTGDEQIHILDLLNKADALEQFLGTKFLGQKRFGLEGAESAIPILDEVLTLAAANHMDSAVLGMAHRGRLNVLVNIVGKRYQDLFGEFEQIIDEDAVQGSGDVKYHLGQRGQFKSVAGNVIDLELAANPSHLETVDPIVLGIARAKMDQIPKNVENKYPVLPILVHGDAAFAGQGVVAETLNLSSIKGYKAGGTIHLVINNQLGFTTPPESARSSEYPTDVAKMVQAPIFHVNGNDPEACVRVARLAYEYRREFGKDVVIDMVCYRKHGHNEGDDPSYTQPLMYQRIDNMAPVRELYTESLVGRGHISLEQAEKAADAYHAELTNALESTREAKPSEPRTVPAPPNPE--GVIGPVATGVDRTELDRIFEALNTVPADFTIHPKLAKQFDTRRKMFEAGEVDWSLGEALAFGSLLAEGTPVRLAGQDSRRGTFSQRHAALVDFHTGDDYLPLSALTTDGSELWIYDSLLSEYAALGFEYGYSVENPDALVMWEAQFGDFVNGASIIVDQYLVAAEDKWKQTSDLVMLLPHGYEGQGPEHSSARIERFLILAAEDNIQLCNVTSAAQYFHLLRRQIHRDGNKPLIIFTPKSGLRAKSYRSPISQFTDGHFCELLPDDSGLDPETVTRVVLASGKVAHEAIERRNQLNVPMAVARVEQLFPWPFAAIETELDRYPNCNEIVWLQEEPENMGPWNGIKGRLYEAFEGRGMQIRRVSRVASGSPATGSSLIHRQEQDEILTKSF 1223
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|505254788|ref|WP_015441890.1| (multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [Ilumatobacter coccineus] >gi|464099761|dbj|BAN02643.1| putative 2-oxoglutarate dehydrogenase E1 component [Ilumatobacter coccineus YM16-304]) HSP 1 Score: 1388.63 bits (3593), Expect = 0.000e+0 Identity = 672/1111 (60.49%), Postives = 837/1111 (75.34%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQVEV-GNYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEV-GPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAFA 1109
ME+SL VPTATSFR +PAKLLEVNRKV+N R GK+SFTH++G+A+VRAIAD +P M + Y+E DGKPR+++ +N+ LAVD++K DG+RTL+ PV+++A ++FA F+A+Y+ +I+KV++NKLTVDD GA +SLTN GT+GTVQSVPRLMPGQG I+GVG IDYP FE AD +A +G+SKVV +TSTYDHRIIQGAESG FLKRV ELL+G FYD +F + +PY AV+W D + E + KQMAV+ LI +RVRGH IA+ +PL T ELDPAT+GLTIWDLDR FLT DGV G +M LG++LGVLRDAYCR+IG+EYMHI + E+RW+QE+VE +Q+ +LERL AAE+ EKFLA +YVG KRFG+EG ES IP+LD +L AAD + AILGMAHRGRLNVL N MGKSY +F EFEG ++ +S+QGSGDVKYHLG KGT+ SPSG + ELA NPSHLETV P+V+G+ RA DQ++ G++PVLPIL+HGDAAFAGQGVV E L +S GY++GGTIH+I NNQ+G+TTAP +RSS Y +DVAK VQAPIFHVN DDPEACVRVA LA+ YR F+KDVVID++ YRRHGHNEGDDPSYTQP+MY+ IAE+ SVR LY + L+ RGDIS+ EAE A+ F D LQ LD TRE AP A+P P VGVLPHI T + LD ++ ++ P+GFTVHPKLA+QF+ R KM+ +GEVDWA EA AIG+L+ +GRSVR AG+D+RRGTF+HRHA L DYE GE F PL + G FW +DS LSEYAALGFEYGY+ AN +ALV+WEAQFGDF+NGAQIIIDQ++VAAEDKWK + + +LLPHGYEGQGPEHSS R+ERFL L AEDN+Q+VN TTA+ FFHLLRRQV + + PL+VF+PK GLR K +RS +E+L G+F+EVLDD ++V R++F SGKVA +A A RD AP AVVR+EQLYP P + + L+KY NA E+ WLQEEPENMGAWN ++ + + + +R V+R ESGSPATGS +H QE +L++ FA
Sbjct: 123 MEASLAVPTATSFRNVPAKLLEVNRKVINGFRARSGQGKISFTHLIGWAVVRAIADEMPGMINTYVEDDDGKPRIIENKHVNMSLAVDKEKPDGSRTLLTPVLRDADTLDFAGFLASYDEIIRKVKNNKLTVDDFMGANVSLTNPGTIGTVQSVPRLMPGQGVIVGVGSIDYPAEFEGADPASLADMGVSKVVTITSTYDHRIIQGAESGMFLKRVKELLLGEHGFYDEIFASLDLPYEAVKWRPDTNPMNRE--EAMLRKQMAVAKLIRVHRVRGHRIADLDPLRWTQPHTPRELDPATYGLTIWDLDREFLT---DGV-----GGTDKMKLGNLLGVLRDAYCRTIGVEYMHIQNTDEQRWVQERVESTQVEFDSEQKMRILERLNAAESFEKFLATKYVGTKRFGIEGAESAIPILDEVLGRAADAGLDSAILGMAHRGRLNVLTNIMGKSYEAVFSEFEGHLDPTSVQGSGDVKYHLGSKGTYVSPSGAEVPIELAANPSHLETVDPIVMGIVRAKQDQIDPPGSFPVLPILIHGDAAFAGQGVVAECLAMSDTGGYRIGGTIHLIINNQIGFTTAPGSARSSPYCSDVAKTVQAPIFHVNGDDPEACVRVARLAWEYRATFNKDVVIDMVCYRRHGHNEGDDPSYTQPLMYKAIAEKRSVRKLYVETLVKRGDISIEEAEQALTDFHDKLQKVLDQTREHAPADVKAARPPSP-VGVLPHIPTGTDKAVLDSIFGQLTRVPDGFTVHPKLAKQFDARAKMYHDGEVDWATAEALAIGSLVLEGRSVRYAGEDTRRGTFSHRHAALIDYEDGEAFVPLDNLDGAGDARFWCFDSLLSEYAALGFEYGYSHANQEALVVWEAQFGDFINGAQIIIDQYIVAAEDKWKQQNGVVLLLPHGYEGQGPEHSSARIERFLTLAAEDNMQIVNTTTASNFFHLLRRQVHQVRQTPLIVFSPKQGLRMKQTRSPIEELTTGSFREVLDDPGDIDPQAVTRIVFCSGKVAWDAIAERDARNAPVAVVRIEQLYPLPTEQMLEILKKYPNAKELRWLQEEPENMGAWNFIEHNTWRVKDQGYDLRHVARAESGSPATGSKKIHDQELAQLMDEVFA 1222
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|1194614251|ref|WP_085946534.1| (multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [Ilumatobacter nonamiensis]) HSP 1 Score: 1381.31 bits (3574), Expect = 0.000e+0 Identity = 666/1114 (59.78%), Postives = 846/1114 (75.94%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQVEV-GNYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEV-GPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAFAGIE 1112
ME+SL VPTATSFR +PAKLLEVNRKV+N R GK+SFTH++G+A+VRAIAD+VP M + + DGKP +V+ +N+ LAVD +K+DG+RTL+ P+I++A + FA F+A+Y+ LI+KV++NKLTVDD GA +SLTN GT+GTVQSVPRLMPGQG I+GVG I +P FE AD +A +GLSKVV +TSTYDHRIIQGAESG FLKRV ELL+G FYD +FQ + +PY AV+W D + E + KQMAV+ LI +RVRGH IA+ +PL T ELDPAT+GLTIWDLDR FLT DGV G +++ LG++LGVLRDAYCR+IG+EYMHI E++W+Q++VE + +LERL AAE+ EKFLA +YVG KRFG+EG ES +P+LD +L AAD+ + A+LGMAHRGRLNVL N MGKSY +F EFEG ++ +S+QGSGDVKYHLG KG + SP+G I ELA NPSHLETV P+V+GM RA DQ++ G++PVLP+L+HGDAAFAGQGVV E L +S GY++GGTIH+I NNQ+G+TTAP ++RSS Y +DVAK VQAPIFHVN DDPEACVRVA+LA+ YRQ F+KDVVID++ YRRHGHNEGDDPSYTQP+MY+ I +R SVR LY ++L+ RGDI++ EAE A+ F LQ ALD TR SAP + ++ +P P VGVLP + T R++LD ++A +++ PEGFT+HPKLA+QFEQR KM+ G++DWALGEA AIG+L+ +GRSVR +G+D+RRGTF+HRHA L DYETGE F PL + G + FWV+DS LSEYAALGFEYGY+ N DALV+WEAQFGDF+NGAQIIIDQ++VAAEDKW + + +LLPHGYEGQGPEHSS R+ERFL L AEDN+Q+VN TTAA FFHLLRRQV ++ + PL+VF+PK GLR K +RS +++L +G+FQEV+DD +SV R++F SGKVA +A A RD+ P A+VRVEQLYP P + L KY NA+E+ WLQEEPENMGAWN ++ + + + +R V+R ESGSPATGS +H QE ++L++ FA E
Sbjct: 115 MEASLDVPTATSFRNVPAKLLEVNRKVINGFRARSGQGKISFTHLIGWAVVRAIADSVPAMKNGFTTDDDGKPLLVQHDHVNMALAVDVEKSDGSRTLLTPIIRDADTLGFAGFLASYDELIRKVQNNKLTVDDFMGANVSLTNPGTIGTVQSVPRLMPGQGLIVGVGSISFPAEFEGADPASLAGMGLSKVVTITSTYDHRIIQGAESGLFLKRVKELLLGEHEFYDEIFQSLDLPYEAVKWRPDTNPINKE--EAMLRKQMAVAKLIRVHRVRGHRIADLDPLRWTEPHTPRELDPATYGLTIWDLDREFLT---DGV-----GGVEKLKLGNLLGVLRDAYCRTIGVEYMHIQSTDEQKWVQDRVETPQQEFGIDDKRRILERLNAAESFEKFLATKYVGTKRFGIEGAESAVPILDVILGNAADDGLDSAVLGMAHRGRLNVLSNIMGKSYEAIFSEFEGHLDPTSVQGSGDVKYHLGAKGKYVSPAGADIAIELAANPSHLETVDPIVMGMVRAKQDQIDPPGSFPVLPLLIHGDAAFAGQGVVAECLAMSDTGGYRIGGTIHLIINNQIGFTTAPGNARSSPYCSDVAKTVQAPIFHVNGDDPEACVRVAQLAWDYRQTFNKDVVIDMVCYRRHGHNEGDDPSYTQPLMYKAIGDRRSVRKLYVESLVKRGDITIDEAEQALTDFHAKLQVALDETRSSAPASMIVPRPPSP-VGVLPPVPTGVDRDRLDSIFAQLTDYPEGFTIHPKLAKQFEQRAKMYESGDIDWALGEALAIGSLVLEGRSVRYSGEDTRRGTFSHRHAALIDYETGEAFVPLDSLEGADDARFWVFDSLLSEYAALGFEYGYSHTNRDALVVWEAQFGDFINGAQIIIDQYIVAAEDKWGQQNGVVLLLPHGYEGQGPEHSSARIERFLTLAAEDNMQIVNTTTAANFFHLLRRQVHQERQTPLIVFSPKQGLRMKQTRSSIDELTQGSFQEVIDDPADLDPESVTRIVFCSGKVAWDAMAERDKREEPVAIVRVEQLYPLPTEQMLAILRKYPNATELRWLQEEPENMGAWNFIEHHTWRVKEQGYDLRHVARVESGSPATGSKTIHDQELEQLMDGIFAPSE 1217
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|684285364|gb|KGA05231.1| (putative 2-oxoglutarate dehydrogenase E1 component [actinobacterium acAcidi]) HSP 1 Score: 1371.68 bits (3549), Expect = 0.000e+0 Identity = 664/1113 (59.66%), Postives = 833/1113 (74.84%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQVEVG-NYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMF-AEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAFAGI 1111
ME SL VPTATSFR +PA+LLEVNRKV+N++ KVSFTHI+ +AIVRAI+D VPNM + Y +DGKP++V+ +N+GLAVD K DGTR L+VPV+ NA ++FA F+ AY+ +++KV+ NKLT+ D GA +S+TN GT+GTVQSVPRLMPGQG I+GVG IDYP F+ +D + LG+SKVV +TSTYDHRIIQGAESG FLKRVHELL+G+ FY+ +F+ + +PY V+W D A+ + E + KQM VSTL+ +RVRGHLIA+ +PL A L ELD AT+GLTIWDL+R FLTG GV S +M L ++LGVLRDAYCR+IGIEYMHI + E+RWIQ +VEG ++ + ++ +LERL AAEA EKFLA +YVG KRFGLEG ES IP++D +++ AAD N + ++GM HRGRLNVL N MGK+Y ++FKEFEG ++ S+QGSGDVKYHLG +GT++S +GN I+ ELA NPSHLETV VV+GM RA D++E + VLP+L+HGDAAFAGQG+V E L +S + GY+VGGTIH++ NNQ+GYTTAP ++RSS Y+TDVAK VQAPIFHVN DDPEAC RVA LAF YRQ+FHKDVVID++ YR HGHNEGDDPSYTQP+MY+ IAE+ SVR +Y + L+ RGDIS+ AE + +Q LQ ALD TR AP AKP P VGVLPH++TA + DR++ ++ P FT HPKL RQF R+ F +G+ +WA+GEA AIG+LL +G VRL G+DSRRGTFAHRHA L DYE +F PL ++ +FWVYDS LSEYAALGFEYGY N + L MWEAQFGDF+NGAQI++DQ+LVAAEDKWK + L +LLPHG+EGQGPEHSS R+ERFL CAEDNIQVVNATTAAQFFH+LRRQ+ RD+RKPLV+FTPK LR K SRSR+ED+ G+FQEVL+D SV+R++ SGKVA +A A RD+ AP AV+RVEQLYP+P + +A+ Y NA EIVWLQEEPENMGAW V+ R++ + +R SR SGSPATGS A+H QE +L++ F+G
Sbjct: 115 MEKSLSVPTATSFRNVPARLLEVNRKVINDYRSLHGLSKVSFTHIIAHAIVRAISDAVPNMRNAYAVAADGKPQLVRNPHVNVGLAVDVDKGDGTRALVVPVLMNADTLSFAGFLVAYDDIVRKVKANKLTIADFQGANVSITNPGTIGTVQSVPRLMPGQGVIVGVGSIDYPAEFQGSDPANLNALGVSKVVTVTSTYDHRIIQGAESGLFLKRVHELLLGSHGFYNDIFRSLDIPYQPVEWSSD--ASPMNREETMMEKQMQVSTLVRVHRVRGHLIADIDPLHWKAPRLPRELDLATYGLTIWDLEREFLTG---GVAGS-----HKMTLDELLGVLRDAYCRTIGIEYMHIQNTDEQRWIQSKVEGATFTPTLDEKLRILERLNAAEAFEKFLATKYVGTKRFGLEGSESMIPIIDEIISAAADQNLDGVVMGMPHRGRLNVLANVMGKNYEQIFKEFEGHISSDSVQGSGDVKYHLGAQGTYKSAAGNEIDVELAANPSHLETVNGVVLGMVRAQQDKIEPPFAFSVLPLLMHGDAAFAGQGIVAEGLAMSDISGYRVGGTIHLVVNNQIGYTTAPKYARSSLYATDVAKTVQAPIFHVNGDDPEACARVARLAFEYRQRFHKDVVIDMLCYRLHGHNEGDDPSYTQPLMYKAIAEKRSVRKMYVEQLVKRGDISLEVAEQVLQDYQSKLQTALDDTRSHAPEKVKAAKPPVP-VGVLPHVNTAIDKATFDRIFNQLTNYPADFTPHPKLVRQFAAREAAFEKDGDFEWAIGEALAIGSLLLEGFDVRLMGEDSRRGTFAHRHAALVDYENETDFIPLQQLPGATGKFWVYDSLLSEYAALGFEYGYAHTNRNTLTMWEAQFGDFINGAQIVLDQYLVAAEDKWKQQNGLVLLLPHGFEGQGPEHSSARVERFLQSCAEDNIQVVNATTAAQFFHVLRRQLHRDIRKPLVIFTPKQPLRMKESRSRLEDVTSGSFQEVLNDPFVTDKSSVKRIVLCSGKVAWDAMAERDKRLAPVAVIRVEQLYPFPIDQINEAIATYPNAKEIVWLQEEPENMGAWQFVEHRIWRVKERGYDLRHTSRVASGSPATGSKAIHDQEHGDLMDETFSGF 1216
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|1320891252|gb|PLS76484.1| (multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [Actinobacteria bacterium]) HSP 1 Score: 1365.52 bits (3533), Expect = 0.000e+0 Identity = 682/1115 (61.17%), Postives = 829/1115 (74.35%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQVEVGNYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFAEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVGPEGTE--FWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPK--AKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAFAGI 1111
ME+SL +PTATS R +PA+LLEVNR +LNNHL R R GKVSFTH++GYA+V+A+ + V MNS Y+ G GKP +V+ + LGLAVD +K DGTR+L+VP IK A ++F F AYE LI+KVR NKLT DD G T+ LTN GT+GTV SVPR+MPGQGAIIGVG +DYP ++AAD +A LG+SKV+ +TSTYDHRIIQGAESG FLKRVH LL+G D FYD +F+ + VPY +W D D KQM V L N YRVRGHLIA+ +PLA HPELDPA++GLTIWDL+R FLT + G+ + LG+ILG+LRDAYCRS+G+EYMHI +P +KRWIQE VEG ++ +Q H+L RL AAEA E+FL +YVGQKRFGLEG ES +P++D +L EAA ++G+ HRGRLN+L N +GKSYGELF+EFEG ++ +++QGSGDVKYH G G SG I+ +A NPSHLE+V PVV GMARA DQ++ G PVLP+L+HGDAAFAGQGVV ETLNLS ++GY+ GGT+H++ NNQLG+TT P +RSS Y+TDVAKMVQAP+FHVN DDPEACVRVA LAFA+RQ F KDVVID++ YRR GHNEGD+P YTQP MY +I R SVR LYT+ L+ RGDI++ EAE A++ F LQ ALD TR SAPP + +PP V VLP +T RE LDRV A + + P+GFTVHPKLARQ E R K++A+GEVDW+L EA A G+LL +G VRLAGQD+RRGTF+ RH+ + DY TG+E PL + G + F+VYDS LSEYAALGFEYGY++A+ DALV WEAQFGDF NGAQ+IID F+VAAEDKW S L MLLPHGYEGQGPEHSS RLERFL L AEDNIQVVNATTAAQ+FHLLRRQV R RKPLVV TPKS LRA+ +RSRVE+L G F EVLDD++ + A +V RVI SGKVA +A A RDE P AVVR+EQLYPWP VA AL +Y A+E+VWLQEEPENMGAW V+ RL E +R +R ESGSPA+GS A+H+ EQ++L+ RAF G+
Sbjct: 91 MEASLTIPTATSARVVPARLLEVNRTILNNHLSRTRTGKVSFTHLIGYAVVKAL-EAVAVMNSAYVAGESGKPAIVRHDHVGLGLAVDTEKPDGTRSLLVPCIKAADTLDFRGFWTAYEELIRKVRTNKLTPDDFAGVTLILTNPGTIGTVHSVPRVMPGQGAIIGVGALDYPAEYQAADPSKLADLGISKVITLTSTYDHRIIQGAESGLFLKRVHALLLGEDRFYDEVFRAMAVPYEPARWRRD--VNPVDKERSHLTKQMQVLRLTNMYRVRGHLIADLDPLAAKEPRTHPELDPASYGLTIWDLEREFLTN-------QLAGRDVR-TLGEILGILRDAYCRSVGVEYMHIQEPDQKRWIQEHVEGVSTDLTLDEQRHILGRLNAAEAFERFLHTKYVGQKRFGLEGGESAVPLIDTVLDEAAKAGLAEVVMGVTHRGRLNILANIVGKSYGELFREFEGDLDPTTVQGSGDVKYHKGAVGKFVGMSGREIQVTMASNPSHLESVCPVVEGMARARQDQLDQGADPVLPMLVHGDAAFAGQGVVAETLNLSALRGYRTGGTVHLVINNQLGFTTTPESARSSVYATDVAKMVQAPVFHVNGDDPEACVRVARLAFAFRQAFRKDVVIDMVCYRRFGHNEGDEPGYTQPQMYERIEGRRSVRKLYTEALVKRGDITLEEAEKALEDFSARLQTALDQTRSSAPPRPTVLVNAPPVV-VLPSPETGVPREVLDRVTAALHDVPDGFTVHPKLARQLEARAKVYADGEVDWSLAEALAFGSLLLEGTDVRLAGQDTRRGTFSQRHSVVVDYRTGDEHVPLAVLAKPGEQGRFFVYDSLLSEYAALGFEYGYSVAHKDALVAWEAQFGDFANGAQVIIDNFVVAAEDKWGQTSGLVMLLPHGYEGQGPEHSSARLERFLTLAAEDNIQVVNATTAAQYFHLLRRQVRRHRRKPLVVLTPKSLLRARHARSRVEELSSGRFIEVLDDSSVSESAAGAVERVILTSGKVAYDAMARRDEASLPVAVVRIEQLYPWPAEQVAAALGRYPQATEVVWLQEEPENMGAWGYVRSRLLALLREDDELRAATRVESGSPASGSAALHQLEQKDLVNRAFHGL 1193
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|949045704|gb|KRO47664.1| (alpha-ketoglutarate decarboxylase, partial [Acidimicrobium sp. BACL27 MAG-120823-bin4]) HSP 1 Score: 1358.97 bits (3516), Expect = 0.000e+0 Identity = 667/1111 (60.04%), Postives = 821/1111 (73.90%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQVEVG-NYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMFA-EGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAFA 1109
ME+SL VPTATS R++PAKLLEVNRKV+N + R K+SFTH++GYAIVRAIAD VPNM VY GKP++ K +N+GLAVD K G R+L+VPV++NA ++FA F+ YE +I+KVR NKLT+DD GA +SLTN GT+GT SVPRLM GQG I+GVG IDYP F+ +D++ + +LG+SKVV +TSTYDHRIIQGAESG FLK VHELL G NFY +F +GVPY +V+W DD + +++D L KQM ++TLI +RVRGHLIA+ +PL A + ELDPAT+GLT+WDLDR FLTG +GG ++ LG++LGVLRDAYCR+IG+EYMHI + E+RWIQE EG + + VLERL AAEA E+FL+ +YVG KRFGLEG ES IP+LD +L AAD + ++GMAHRGRLNVL N +GK Y ++F+EFEG V+ SS+QGSGDVKYHLG G + SG+ + EL NPSHLETV PVV+G RA DQ+E Y VLP+ +HGDAAFAGQGVV E L +S GY+VGGTIH+I +NQ+G+TT+P ++RSS+Y +DVAK VQAPIFHVN DDPEACVRVA+LAF YRQ+FHKDVVID+I YRR+GHNEGDDPSYTQP+MY+ IAER SVR LY + L+ RGDISV +AE ++ +Q LQGAL+ TR + A+P P +GV+PHI+T R+ LD V A +S P+ F VHPKL RQFE RD A EGEVDWA EA AIG+L+ +G SVRLAGQDSRRGTF+HRH+TL DY + PL ++ FWVYDS LSEYAALGFEYGY AN ALVMWEAQFGDFVNGAQIIIDQ+LVAAEDKW+ + L +LLPHGYEGQGPEHSS R+ERFL LCAEDNIQV N TT+AQ+FHLLRRQV +D KPLV+F+PK LR K SRS + L G+F E+LDD A + RVIF SGKVA +A A RD+ GA A+VR+EQLYP+P + + L KY+NA E+VWLQEEPENMG V R++ E +++ V+R ESGSPATGS +H QE +L+ + FA
Sbjct: 22 MEASLAVPTATSVRQVPAKLLEVNRKVINGYRERSGESKISFTHLIGYAIVRAIADAVPNMKHVYSVDEQGKPQIKKFNRVNMGLAVDVDKGKGQRSLVVPVLRNADTLDFAGFLLTYEDIIRKVRANKLTLDDFQGANVSLTNPGTIGTQMSVPRLMAGQGLIVGVGTIDYPAEFQGSDERALGRLGVSKVVTITSTYDHRIIQGAESGMFLKYVHELLTGEHNFYADVFSSLGVPYESVKWRDDSNSLDSED--ALLEKQMQIATLIRVHRVRGHLIADLDPLHWRAPRMPRELDPATYGLTVWDLDREFLTG-------GVGGVSRS-TLGELLGVLRDAYCRTIGVEYMHIQNTDEQRWIQEHFEGVKRNDFEVDKIRVLERLNAAEAFERFLSTKYVGTKRFGLEGAESAIPILDKILNLAADAKMDGTVIGMAHRGRLNVLANVVGKEYDQIFQEFEGYVDPSSVQGSGDVKYHLGAIGEFVAQSGSKVHVELVSNPSHLETVNPVVLGTVRAMQDQIEPPLAYSVLPLAIHGDAAFAGQGVVAECLAMSDTSGYRVGGTIHLIIDNQIGFTTSPEYARSSQYCSDVAKTVQAPIFHVNGDDPEACVRVAQLAFEYRQKFHKDVVIDMICYRRYGHNEGDDPSYTQPLMYKAIAERRSVRKLYVETLVKRGDISVEQAEKSLTDYQAKLQGALEQTRAKTTEKVIAARPPAP-IGVVPHIETGVPRQNLDAVLAQLSNYPDDFMVHPKLLRQFEARDATVANEGEVDWATAEALAIGSLVLEGTSVRLAGQDSRRGTFSHRHSTLVDYLNETRWVPLAQIPGAAGRFWVYDSLLSEYAALGFEYGYAHANQKALVMWEAQFGDFVNGAQIIIDQYLVAAEDKWQQRNGLVLLLPHGYEGQGPEHSSARIERFLQLCAEDNIQVCNPTTSAQYFHLLRRQVKQDHLKPLVIFSPKQPLRMKQSRSTLNSLSTGSFSEILDDPTISNADEISRVIFCSGKVAWDAFAERDKRGAKYAIVRLEQLYPFPIEQIRQILAKYKNAKELVWLQEEPENMGPRYFVDDRIWSLKQEGYKLHHVARVESGSPATGSKTIHDQELDDLMAQTFA 1121
BLAST of alpha-ketoglutarate partial vs. nr
Match: gi|1272474439|gb|PHX72424.1| (2-oxoglutarate dehydrogenase E1 component [Acidimicrobium sp.]) HSP 1 Score: 1356.27 bits (3509), Expect = 0.000e+0 Identity = 666/1113 (59.84%), Postives = 834/1113 (74.93%), Query Frame = 0
Query: 1 MESSLGVPTATSFREIPAKLLEVNRKVLNNHLLRVRGGKVSFTHIMGYAIVRAIADTVPNMNSVYLEGSDGKPRVVKGGPINLGLAVDQQKADGTRTLIVPVIKNAGAMNFAEFVAAYEALIKKVRDNKLTVDDMTGATISLTNVGTLGTVQSVPRLMPGQGAIIGVGRIDYPTAFEAADKKVIAQLGLSKVVNMTSTYDHRIIQGAESGSFLKRVHELLIGTDNFYDSMFQDIGVPYTAVQWLDDHGATEADDTEGLHAKQMAVSTLINQYRVRGHLIANTNPLAETASDLHPELDPATFGLTIWDLDRTFLTGIRDGVYASIGGQAKQMALGDILGVLRDAYCRSIGIEYMHIADPAEKRWIQEQVEGNPYSISRQQQHHVLERLTAAEALEKFLAARYVGQKRFGLEGLESTIPVLDALLTEAADNNHNRAILGMAHRGRLNVLVNTMGKSYGELFKEFEGAVNESSIQGSGDVKYHLGLKGTHESPSGNVIETELAPNPSHLETVGPVVVGMARAYMDQVEVG-NYPVLPILLHGDAAFAGQGVVPETLNLSQVKGYKVGGTIHVITNNQLGYTTAPHHSRSSEYSTDVAKMVQAPIFHVNADDPEACVRVAELAFAYRQQFHKDVVIDLIGYRRHGHNEGDDPSYTQPMMYRKIAERPSVRTLYTQNLIDRGDISVAEAESAMDYFQDILQGALDATRESAPPAGLLAKPSPPAVGVLPHIDTAATREQLDRVYALMSETPEGFTVHPKLARQFEQRDKMF-AEGEVDWALGEAFAIGTLLDQGRSVRLAGQDSRRGTFAHRHATLHDYETGEEFTPLTEVGPEGTEFWVYDSTLSEYAALGFEYGYTLANPDALVMWEAQFGDFVNGAQIIIDQFLVAAEDKWKTHSSLTMLLPHGYEGQGPEHSSGRLERFLLLCAEDNIQVVNATTAAQFFHLLRRQVMRDVRKPLVVFTPKSGLRAKWSRSRVEDLLEGTFQEVLDDTNAPKAKSVRRVIFASGKVAAEAQAHRDEIGAPAAVVRVEQLYPWPFADVAKALEKYRNASEIVWLQEEPENMGAWNAVKGRLYEAHGETHRIRRVSRTESGSPATGSLAVHKQEQQELLERAFAGI 1111
ME SL VPTATSFR +PA+LLEVNRKV+N++ KVSFTHI+ +AIVRAI+D VPNM + Y +DGKP++V+ +N+GLAVD K DGTR L+VPV+ NA ++FA F+ AY+ +++KV+ NKLT+ D GA +S+TN GTLGTVQSVPRLMPGQG I+GVG IDYP F+ +D + LG+SKVV +TSTYDHRIIQGAESG FLKRVHELL+G+ FY+ +F+ + +PY V+W D A+ + E L KQM VSTL+ +RVRGHLIA+ +PL A L ELD AT+GLTIWDL+R FLTG GV S +M L ++LGVLRDAYCR+IGIEYMHI + E+RWIQ +VEG ++ ++ +LERL AAEA EKFLA +YVG KRFGLEG ES IP++DA+++ AAD N + ++GM HRGRLNVL N MGK+Y ++FKEFEG ++ S+QGSGDVKYHLG +GT+ S GN I+ ELA NPSHLETV VV+GM RA D++E + VLP+L+HGDAAFAGQG+V E L +S + GY+VGGTIH++ NNQ+GYTTAP ++RSS Y+TDVAK VQAPIFHVN DDPEACVRVA LAF YRQ+FHKDVVID++ YR HGHNEGDDPSYTQP+MY+ IAE+ SVR +Y + L+ RGDIS+ AE + +Q LQ ALD TR AP AKP P VGVLPH++TA + DR+++ ++ P FT HPKL RQF R+ + +G+ +WA+GEA AIG+LL +G VRL G+DSRRGTFAHRHA L DYE ++F PL ++ +FWVYDS LSEYAALGFEYGY N + L MWEAQFGDF+NGAQI++DQ+LVAAEDKWK + L +LLPHG+EGQGPEHSS R+ERFL CAEDNIQVVNATTAAQFFH+LRRQ+ RD+RKPLV+FTPK LR K SRSR+ED+ G+FQEVL+D SV+R++ SGKVA +A + RD+ AP AVVRVEQLYP+P + +A+ Y NA EIVWLQEEPENMGAW V+ R++ + +R +R SGSPATGS A+H QE +L++ F+G
Sbjct: 114 MEKSLSVPTATSFRNVPARLLEVNRKVINDYRSLHGLSKVSFTHIIAHAIVRAISDAVPNMRNAYAVAADGKPQLVRNPHVNVGLAVDVDKGDGTRALVVPVLMNADTLSFAGFLVAYDEIVRKVKANKLTIADFQGANVSITNPGTLGTVQSVPRLMPGQGVIVGVGSIDYPAEFQGSDPANLNALGVSKVVTVTSTYDHRIIQGAESGLFLKRVHELLLGSHGFYNDIFRSLDIPYQPVEWSSD--ASPMNREETLMEKQMQVSTLVRVHRVRGHLIADIDPLHWKAPRLPRELDLATYGLTIWDLEREFLTG---GVAGS-----HKMTLDELLGVLRDAYCRTIGIEYMHIQNMDEQRWIQSKVEGATFTPRLDEKLRILERLNAAEAFEKFLATKYVGTKRFGLEGSESMIPIIDAIVSAAADQNLDGVVVGMPHRGRLNVLANVMGKNYEQIFKEFEGHISSDSVQGSGDVKYHLGAQGTYTSADGNEIDIELAANPSHLETVNGVVLGMVRAKQDKIEPPFAFSVLPLLMHGDAAFAGQGIVAEGLAMSDISGYRVGGTIHLVVNNQIGYTTAPKYARSSLYATDVAKTVQAPIFHVNGDDPEACVRVARLAFEYRQRFHKDVVIDMLCYRLHGHNEGDDPSYTQPLMYKAIAEKRSVRKMYIEQLVKRGDISLEVAEQVLQDYQSKLQIALDDTRSHAPEKVKAAKPPEP-VGVLPHVNTAIDKATFDRIFSQLTNYPADFTPHPKLVRQFAAREAAYEKDGDFEWAIGEALAIGSLLLEGFDVRLMGEDSRRGTFAHRHAALVDYENEKDFIPLQQLPGATGKFWVYDSLLSEYAALGFEYGYAHTNRNTLTMWEAQFGDFINGAQIVLDQYLVAAEDKWKQQNGLVLLLPHGFEGQGPEHSSARVERFLQSCAEDNIQVVNATTAAQFFHVLRRQLHRDIRKPLVMFTPKQPLRMKESRSRLEDVTSGSFQEVLNDPFVSDKASVKRIVLCSGKVAWDAMSERDKRVAPVAVVRVEQLYPFPIDQINEAIASYPNAKEIVWLQEEPENMGAWQFVEHRIWRVKERGYDLRHTARVASGSPATGSKAIHDQEHVDLMDDTFSGF 1215 The following BLAST results are available for this feature:
BLAST of alpha-ketoglutarate partial vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 5
BLAST of alpha-ketoglutarate partial vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of alpha-ketoglutarate partial vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold6640_size3701:225..3563- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>snap_masked-scaffold6640_size3701-processed-gene-0.0 ID=snap_masked-scaffold6640_size3701-processed-gene-0.0|Name=alpha-ketoglutarate partial|organism=Tigriopus kingsejongensis|type=gene|length=3339bp|location=Sequence derived from alignment at scaffold6640_size3701:225..3563- (Tigriopus kingsejongensis)back to top Synonyms
The feature 'alpha-ketoglutarate partial' has the following synonyms
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