BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000002424 (supercontig:LSalAtl2s:LSalAtl2s145:98262:104743:1 gene:EMLSAG00000002424 transcript:EMLSAT00000002424 description:"maker-LSalAtl2s145-augustus-gene-1.8")

HSP 1 Score: 198.749 bits (504), Expect = 3.797e-53
Identity = 114/251 (45.42%), Postives = 155/251 (61.75%), Query Frame = 0

Query:  500 AMLYLQMQLCDRTLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREG-NIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLETLFSDEAKEKQKLEDRVKYLSDLVDRQREELQAKNDVIRS 748
            A+LYLQM+LC+ TLR W+D R +++         LD  +N  IF QIL GV+YIHSQGIIHRDLKPRNIF+ +R+  VQIGDFGLAK ++   V  P +P   LE     F    K  +S VGT AY +PEQL  G V+ KSDIYSLGI+L+ELF  F T MERS AIT ++E   I   F   +P++++ +  +    P  RP+A +LL + FS E + +  L      L + +D + +EL+   ++I S
Sbjct:  298 AILYLQMELCEITLRGWMDNRASSSLSV------LDSKVNTQIFTQILEGVSYIHSQGIIHRDLKPRNIFIRNRDCHVQIGDFGLAKDEIQKKVVPPESP---LENNIIKF----KKVSSCVGTHAYASPEQLSLGWVDYKSDIYSLGIVLYELFSNFKTGMERSVAITKLKENLVIDTVFERKFPQIAQYVLWLTRSSPHSRPTAQELLNSEFSKEGQLRLSLLTENIILKESLDEKNKELETYKNIIAS 535          

HSP 2 Score: 121.324 bits (303), Expect = 2.182e-28
Identity = 73/186 (39.25%), Postives = 98/186 (52.69%), Query Frame = 0

Query:   87 MPFVFHMVLHHLCSFYESAPERREQLSQELCHRL--AIPLRTPVLYEFPELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDL--FAKIFREVTTLAQLNHPNVVSYKTAWLEP 268
            M  +   +L  L S YE    RR +L + +   +    P    V    P L  LR  YQ +F +L+K +Q+ L    A     +                 + D    SRYR EFEE+ ++AKGGFG VFR RNKLD   YA+KKI+LK CD D   F ++ +EV  LA+L HPN+V+YKTAW+EP
Sbjct:   28 MSVIIQSLLDLLLSCYEQNDARRSKLLELMWESMIKVFPCSNSV--NSPALMQLRGQYQTVFKKLIKISQKKLGYSSALSLDIKL----------------DSDYTHLSRYRSEFEEIEYLAKGGFGSVFRVRNKLDHFEYAIKKILLK-CDKDWTNFTEVTKEVIMLAKLTHPNIVNYKTAWIEP 194          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000004755 (supercontig:LSalAtl2s:LSalAtl2s250:368617:373699:1 gene:EMLSAG00000004755 transcript:EMLSAT00000004755 description:"maker-LSalAtl2s250-augustus-gene-3.12")

HSP 1 Score: 132.88 bits (333), Expect = 3.772e-32
Identity = 86/216 (39.81%), Postives = 120/216 (55.56%), Query Frame = 0

Query:  499 RAMLYLQMQLCDR-TLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNN-EVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKS--HTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKK-IQSVLSKVPSLRPSASDLLET 709
            R+ LY+ MQLC + +L+DWL      + ++   S++  V   + IF QI  GV Y H  G+IHRDLKP NIF S+ +  ++IGDFGL            H   D  EP  +LF   E +  HT  VGT+ Y +PEQL     N K DI+S+G+ILFEL   F T MER + +  ++ GN   A  E   +M K  +  ++S+ P+ RP  S+LL T
Sbjct:  698 RSYLYIVMQLCHKESLKDWL-----TSPETCSFSHASRVQQAIQIFHQICLGVEYFHKMGLIHRDLKPGNIFFSKTDGTIKIGDFGLV----------THVELD-FEPNGELFSCPESNLRHTDRVGTELYMSPEQLANKSYNHKVDIFSMGLILFELLVTFSTQMERIQCLRDLKNGNNLKA--ELAGKMFKGLVTEMISEDPNHRPEVSELLST 895          

HSP 2 Score: 63.929 bits (154), Expect = 1.187e-10
Identity = 32/75 (42.67%), Postives = 46/75 (61.33%), Query Frame = 0

Query:  193 SRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE 267
            SR+  ++  L  + +GGFG+VF  +NK+D   YAVK+I L   +     K+ REV  LA+L+H N+V Y   WLE
Sbjct:  510 SRFESDYIPLQSLGRGGFGIVFECKNKIDDTHYAVKRIRLPRSEHSK-KKVMREVKFLAKLDHRNIVRYYHTWLE 583          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000005503 (supercontig:LSalAtl2s:LSalAtl2s297:129260:135237:1 gene:EMLSAG00000005503 transcript:EMLSAT00000005503 description:"maker-LSalAtl2s297-augustus-gene-1.35")

HSP 1 Score: 117.857 bits (294), Expect = 3.411e-27
Identity = 83/227 (36.56%), Postives = 117/227 (51.54%), Query Frame = 0

Query:  501 MLYLQMQLCDR-TLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSH-----------TSGVGTQAYGAPE--QLQFGVVNDKSDIYSLGIILFEL-FHPFGTAMERSKAITLIREGNI--PLAFLE-AYPRMSKKIQSVLSKVPSLRPSASDLLET 709
             LY+QM+LCD+ TLR+ +D                D      +F +I+ G+ +IHSQG+IHRDLKP N+F+   + V+IGDFGLA   +    S      D  E    L  + E +            T  +GT  Y APE  +++  V N K DIYSLGII FE+ +HP  T MER K +T +R   I  P  F E    +    I+ +L+  P  RPS+ +LL++
Sbjct:  802 FLYIQMELCDKQTLRNAID-----------KDLFKDTKRVWRMFREIIEGLLHIHSQGMIHRDLKPVNVFIDSTDHVKIGDFGLATSSIIMGGSKGSEKTDFNESSSSLEVSMEFTCNKNGVIQPCDLTGQIGTAMYIAPEVQKMRSTVYNQKVDIYSLGIIFFEMCYHPLKTGMERIKILTDLRSEEIIFPSDFDEHVMEQQGFLIRWLLNHDPMQRPSSFELLQS 1017          

HSP 2 Score: 78.9518 bits (193), Expect = 3.149e-15
Identity = 42/90 (46.67%), Postives = 55/90 (61.11%), Query Frame = 0

Query:  193 SRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE-PLLDSPTDLRRDRS 281
            SR   EFE +  I KGGFG V + +N+LDG  YA+KKI L   D  +  KI REV  L++LNH NVV Y  +W+E   L++ +D   D S
Sbjct:  577 SRLNDEFELISHIGKGGFGEVIKVKNRLDGQTYAIKKIKLNPRDKSVTKKIMREVKLLSRLNHENVVRYYNSWMEVATLEADSDSEGDDS 666          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000005433 (supercontig:LSalAtl2s:LSalAtl2s292:565959:573639:1 gene:EMLSAG00000005433 transcript:EMLSAT00000005433 description:"maker-LSalAtl2s292-augustus-gene-5.11")

HSP 1 Score: 81.2629 bits (199), Expect = 7.022e-17
Identity = 58/166 (34.94%), Postives = 79/166 (47.59%), Query Frame = 0

Query:  543 FEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFE---LFHPF-GTAMERSKAITLIREGNIPLAFLEAYP-RMSKKIQSVLSKVPSLRPSA 703
            F QI   + Y+HS+ I+HRD+KP N+F++ N E ++GD GL +   S+N    H                     S VGT  Y +PE++     N KSDI+SLG +L+E   L  PF G  ME S     I   + P    E Y       +   L K PS RP+A
Sbjct:  130 FVQICSALDYMHSKRIMHRDIKPANVFITANGEAKLGDLGLGRF-FSSNTMAAH---------------------SLVGTPYYMSPERIHEEGYNFKSDIWSLGCLLYEMAALHSPFYGDKMELSSLCQKIEHADYPTLSSELYSDSFISLVDETLQKDPSSRPNA 273          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000010815 (supercontig:LSalAtl2s:LSalAtl2s718:102476:108918:1 gene:EMLSAG00000010815 transcript:EMLSAT00000010815 description:"maker-LSalAtl2s718-augustus-gene-1.15")

HSP 1 Score: 82.8037 bits (203), Expect = 1.525e-16
Identity = 54/184 (29.35%), Postives = 90/184 (48.91%), Query Frame = 0

Query:  537 SLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFE---LFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLETLFSDEAKE 717
            +L L  F QI   V YIH + I+HRD+K +NI +S+N   ++GDFG+A+                      +   +     + VGT  Y +PE  +    N+KSD+++LG +L+E   L H F     ++  + +IR    P++    Y  +   IQ++L K  S RPS + +    F  +A++
Sbjct:  327 TLILGYFVQICRAVEYIHERKILHRDIKSQNILISKNRVCKLGDFGIAR----------------------IIDGTTDYAKTCVGTPYYLSPEVWENKPYNNKSDLWALGCVLYEMTTLKHAFEAGCMKNLILKIIRGSYPPISPTYTYD-LRNLIQALLRKKASDRPSLTSIFRKGFIKKAEQ 487          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000010806 (supercontig:LSalAtl2s:LSalAtl2s716:155313:159814:-1 gene:EMLSAG00000010806 transcript:EMLSAT00000010806 description:"maker-LSalAtl2s716-augustus-gene-1.11")

HSP 1 Score: 78.5666 bits (192), Expect = 3.473e-15
Identity = 54/204 (26.47%), Postives = 98/204 (48.04%), Query Frame = 0

Query:  540 LHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFEL--FHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLL------ETLFSDEAKEKQKLEDRVKYLSDLVDRQ 735
            L IF Q++  + ++HS  ++HRDLK  NIFL++   V++GDFG++K      +ST H                     + +GT  Y +PE  +  + ++KSDI++LG IL+E+   H           +  I  G       +  P   + ++ +L + P  RP+AS ++         F++  + +++ EDR  ++   +DR 
Sbjct:  301 LDIFCQMVSAIRHMHSHNVLHRDLKTANIFLTKEGIVKVGDFGISKV-----LSTHHG-----------------GAMTVLGTPYYISPEMCEGKIYDEKSDIWALGCILYEMACLHKTFEGANLPALVNKIVRGQFAPIKGDYSPLFKQLVRDLLQRDPDFRPTASHVMLVRLPELVAFNESLRVQEEEEDRDAFIIQELDRN 482          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000008315 (supercontig:LSalAtl2s:LSalAtl2s503:403257:406200:1 gene:EMLSAG00000008315 transcript:EMLSAT00000008315 description:"maker-LSalAtl2s503-augustus-gene-4.13")

HSP 1 Score: 77.411 bits (189), Expect = 6.356e-15
Identity = 78/291 (26.80%), Postives = 127/291 (43.64%), Query Frame = 0

Query:  442 EEDRTSSRGGRLKPREESPLKA-PLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQH-----------DRAMLYLQMQLCDRTLRDWLDV-RNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFH---PFGT-AMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLETLFSDEA 715
            ++ R   +GG  K  E + + +  + +   + + LLT  H  +    E   QK F H           D   +Y+ ++LC R  R  +++ +   A    ++ Y ++         QIL G  Y+H   +IHRDLK  NIFL+ + EV+IGDFGLA                      ++ +  E+  T   GT  Y APE L     + + D++SLG I++ L     PF T  ++ + A     E ++P       P     I  +L   PS RP+ +++L+  F   A
Sbjct:   32 QKGRFLGKGGFAKCYELTDMASGEVVAGKIVPKSLLTKQHQREKMSQEIRLQKTFNHTYIVKLYSYFEDSNFVYIILELCRR--RSLMELHKRRKAITEPETRYFMN---------QILQGCLYLHENKVIHRDLKLGNIFLNDDMEVKIGDFGLAT---------------------KVDYFGERKRTL-CGTPNYIAPEVLAKKGHSYEVDVWSLGCIMYTLLVGKPPFETQTLKDTYARIKKNEYHVP---SRVGPLAKNLITKLLQSDPSKRPAVAEILKDEFMTMA 286          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000000951 (supercontig:LSalAtl2s:LSalAtl2s1166:40390:44816:1 gene:EMLSAG00000000951 transcript:EMLSAT00000000951 description:"augustus_masked-LSalAtl2s1166-processed-gene-0.5")

HSP 1 Score: 75.8702 bits (185), Expect = 1.337e-14
Identity = 69/234 (29.49%), Postives = 108/234 (46.15%), Query Frame = 0

Query:  525 CDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQL-QFGVVNDKSDIYSLGIILFELFHPFGTAMERS----KAITLIREGNIPL------------AFLEAYPRMSKKIQSVLSKVPSLRPSASDLLE-TLFSDEAKEKQKLEDRVKYLSDLVDRQREELQ 740
            C SG     LD      + +++L G+ Y+H+ G IHRD+K  NI L    +VQI DFG     +SA + T    N              KS  + VGT  + APE + Q    + K+DI+S GI   EL    GTA        K + L  +   P             AF + + +M   I   L K PS RP+A++LL+   F  +AK+++ L+  +   +  +D + ++++
Sbjct:  146 CKSG----VLDEVTIATVLKEVLRGLEYLHNNGHIHRDIKAGNILLGSEGQVQIADFG-----VSAWLXTGGEMN------------RAKSRHTFVGTPCWMAPEVMEQVTGYDYKADIWSFGITAVEL--ATGTAPYHKYPPMKVLMLTLQNXPPTLDTNAEDKEQYKAFGKTFRKM---ISECLQKDPSKRPTATELLKHQFFKSKAKDRKYLQQNIIASAPTIDSRSQKIK 353          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000003670 (supercontig:LSalAtl2s:LSalAtl2s19:285003:288210:1 gene:EMLSAG00000003670 transcript:EMLSAT00000003670 description:"maker-LSalAtl2s19-augustus-gene-3.22")

HSP 1 Score: 75.485 bits (184), Expect = 2.909e-14
Identity = 64/235 (27.23%), Postives = 112/235 (47.66%), Query Frame = 0

Query:  494 GFQHDRAMLYLQMQLCD-----RTLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEV-QIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFEL--FHPFGTAMERSKAITLIREG---NIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEAK 716
            G   D  +LY+ M+  D     + +  W +       +S   ++ + ++L L+          Y+H + I+HRDLK  NIF++  N++ ++GDFG+++                      L H +E + T+G+GT    +PE  Q    N KSDI+SLG +L+E+    P  +  E +  +  I +G    +P  F +    +   ++ +L  +P  RPSAS +L + +F DE K
Sbjct:  108 GGNEDEVILYMVMEYADGGDLHQYINKWREENKTYMSESKILNWFIQIALALN----------YLHREMILHRDLKTHNIFVTAGNKILKLGDFGISR---------------------TLSHENEFA-TTGIGTPQXLSPEMCQSQPYNYKSDIWSLGCVLYEMCVLEPAFSGNELAPLVQKIVKGEYKTLPSHFSD---HIKDLVKVLLRPIPEKRPSASQILSSPIFIDEVK 307          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. L. salmonis genes
Match: EMLSAG00000000389 (supercontig:LSalAtl2s:LSalAtl2s1062:164646:204460:1 gene:EMLSAG00000000389 transcript:EMLSAT00000000389 description:"maker-LSalAtl2s1062-augustus-gene-2.14")

HSP 1 Score: 69.707 bits (169), Expect = 1.676e-12
Identity = 43/119 (36.13%), Postives = 59/119 (49.58%), Query Frame = 0

Query:  542 IFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVV--------NDKSDIYSLGIILFEL 652
            IF+QIL  VA+ H  GI+HRDLKP NI L  NN V++ DFG A++         HT         +LF           GT  Y APE L  G+V        N + D ++ G+I++ +
Sbjct:  179 IFKQILEAVAHCHKLGIVHRDLKPENILLDDNNIVKLTDFGFARK-------IKHTD--------RLFETC--------GTPGYLAPEVLMAGMVDXNKCTGYNIEVDAWACGVIMYTM 274          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|462439|sp|P33279.1|E2AK1_RABIT (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1; AltName: Full=Heme-controlled repressor; Short=HCR; AltName: Full=Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; AltName: Full=Heme-regulated inhibitor; AltName: Full=Hemin-sensitive initiation factor 2-alpha kinase)

HSP 1 Score: 167.548 bits (423), Expect = 1.213e-42
Identity = 93/219 (42.47%), Postives = 134/219 (61.19%), Query Frame = 0

Query:  501 MLYLQMQLCDRTLRDWLDVRN--AAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEA 715
            ML++QMQLC+ +L DW+  RN  +  C    +   + VS+   IF++++ GV YIH+ GI+HRDLKPRNIFL   + +V+IGDFGLA  D+    +   + N    P          +HTS VGT  Y +PEQL+    + KSD+YS+G+IL ELF PFGT MER++ +T +R G IP +  +  P  +K +Q +  +  S RPSA  LL++ LF + A
Sbjct:  374 MLHIQMQLCELSLWDWIAERNRRSRECVDESACPYVMVSVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACADIIQKNAARTSRNGERAP----------THTSRVGTCLYASPEQLEGSEYDAKSDMYSVGVILLELFQPFGTEMERAEVLTGVRAGRIPDSLSKRCPAQAKYVQLLTRRNASQRPSALQLLQSELFQNSA 582          

HSP 2 Score: 113.235 bits (282), Expect = 1.054e-24
Identity = 73/206 (35.44%), Postives = 105/206 (50.97%), Query Frame = 0

Query:  102 YESAPERREQLSQELCHRLAIPLRTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE---------------PLLDSPTDLRRDRSSHSMQNMA 289
            +E  P R  Q+ + LC      ++  +L  F    E S+LR H+      L++SA+    +R+   P A  S++ K RS +   E       Q SRY +EFEEL  + KGG+G V++ RNKLDG  YA+KKI++K        K+ REV  LA L HPN+V Y TAW+E               P L+  +D   DR  + ++N A
Sbjct:   83 HEPNPLRSRQVFKLLCQTF---IKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAR----ERVRQDPCADNSHIQKIRSREVALEA------QTSRYLNEFEELSILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTDCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVHVQADRVPIQLPSLEVLSDQEEDRDQYGVKNDA 275          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|327478507|sp|Q9Z2R9.2|E2AK1_MOUSE (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1; AltName: Full=Heme-controlled repressor; Short=HCR; AltName: Full=Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; AltName: Full=Heme-regulated inhibitor; AltName: Full=Hemin-sensitive initiation factor 2-alpha kinase)

HSP 1 Score: 164.466 bits (415), Expect = 1.237e-41
Identity = 91/213 (42.72%), Postives = 127/213 (59.62%), Query Frame = 0

Query:  501 MLYLQMQLCDRTLRDWLDVRNAAA---CDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET 709
            ML++QMQLC+ +L DW+  RN  +    D     Y +  S+   IF++++ GV YIH+ GI+HRDLKPRNIFL   + +V+IGDFGLA  D+  N    +                 ++HTS VGT  Y +PEQL+    + KSD+YSLG+IL ELF PFGT MER+  +T +R G IP +  +  P  +K IQ +  +  S RPSA  LL++
Sbjct:  377 MLHIQMQLCELSLWDWITERNKRSREYVDEAACPYVM-ASVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACADIIQNADWTNRNG-----------KGTRTHTSRVGTCLYASPEQLEGSQYDAKSDMYSLGVILLELFQPFGTEMERATVLTGVRTGRIPESLSKRCPVQAKYIQLLTGRNVSQRPSALQLLQS 577          

HSP 2 Score: 105.531 bits (262), Expect = 2.288e-22
Identity = 64/169 (37.87%), Postives = 91/169 (53.85%), Query Frame = 0

Query:  102 YESAPERREQLSQELCHRLAIPLRTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE 267
            +E  P   +Q+ + LC      ++  +L  F    E S+LR H+      L++SA+    +R+   P    S + K RS +   E       Q SRY +EFEEL  + KGG+G V++ RNKLDG  YA+KKI++K        K+ REV  LA L HPN+V Y TAW+E
Sbjct:   80 HEPNPLHSKQVFKLLCQTF---IKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAK----ERVRQDPCQDNSYMQKIRSREIAFEA------QTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVLAGLQHPNIVGYHTAWIE 235          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|75077022|sp|Q4R8E0.1|E2AK1_MACFA (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1; AltName: Full=Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; AltName: Full=Hemin-sensitive initiation factor 2-alpha kinase)

HSP 1 Score: 163.31 bits (412), Expect = 3.623e-41
Identity = 91/212 (42.92%), Postives = 128/212 (60.38%), Query Frame = 0

Query:  501 MLYLQMQLCDRTLRDWLDVRNAAACDSGQSSYSLDVSLNL--HIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET 709
            ML++QMQLC+ +L DW+  RN  + +    S    V  N+   IF++++ GV YIH+ GI+HRDLKPRNIFL   + +V+IGDFGLA  D+    +     N    P          +HTS VGT  Y +PEQL+    + KSD+YSLG+IL ELF PFGT MER++ +T +R G +P +  +  P  +K IQ +  +  S RPSA  LL++
Sbjct:  379 MLHIQMQLCELSLWDWIAERNKRSRECVDESACPYVMANVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNADWTNRNGKRTP----------THTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVILLELFQPFGTEMERAEVLTGLRTGQLPESLSKRCPVQAKYIQHLTRRNSSQRPSAVQLLQS 580          

HSP 2 Score: 115.931 bits (289), Expect = 1.457e-25
Identity = 81/265 (30.57%), Postives = 129/265 (48.68%), Query Frame = 0

Query:  102 YESAPERREQLSQELCHRLAIPLRTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE----------------PLLDSPTDLRRDRSSHSMQNMAAEVWS-VYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVND 346
            +E  P R  Q+ + LC      ++  +L  F    E S+LR H+      L++SA+    +R+   P    S++ K RS +   E       Q SRY +EFEE+  + KGG+G V++ RNKLDG  YA+KKI++K        K+ REV  LA L HPN+V Y TAW+E                P L+  +D   DR  + ++N  +   S V+++P        G+ D E   ++ +++  ++ +V  D   +E     + ND
Sbjct:   80 HEPNPLRSRQVFKLLCQTF---IKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAK----ERVRQDPCEDVSHIQKIRSREVAFEA------QTSRYLNEFEEVAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTDCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVIQPRADRAAIELPTLEVLSDQEEDREQYDVKNDESSSSSIVFAEPTPEKGKRFGESDTEN--QNDKSVKYTTSLVIRDSGELESTLELQEND 329          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|327478508|sp|Q63185.2|E2AK1_RAT (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1; AltName: Full=Heme-controlled repressor; Short=HCR; AltName: Full=Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; AltName: Full=Heme-regulated inhibitor; AltName: Full=Hemin-sensitive initiation factor 2-alpha kinase)

HSP 1 Score: 162.925 bits (411), Expect = 4.666e-41
Identity = 91/213 (42.72%), Postives = 126/213 (59.15%), Query Frame = 0

Query:  501 MLYLQMQLCDRTLRDWLDVRNA---AACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET 709
            ML++QMQLC+ +L DW+  RN       D     Y +  S+   IF++++ GV YIH+ GI+HRDLKPRNIFL   + +V+IGDFGLA  D+    +     N    P          +HTS VGT  Y +PEQL+    + KSD+YSLG+IL ELF PFGT MER+  +T +R G IP +  +  P  +K IQ +  +  + RPSA  LL++
Sbjct:  377 MLHIQMQLCELSLWDWIAERNNRSRECVDEAACPYVM-ASVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACADIIQKSADWTNRNGKGTP----------THTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVILLELFQPFGTEMERATVLTGVRTGRIPESLSKRCPVQAKYIQLLTGRNAAQRPSALQLLQS 578          

HSP 2 Score: 105.531 bits (262), Expect = 2.574e-22
Identity = 64/169 (37.87%), Postives = 91/169 (53.85%), Query Frame = 0

Query:  102 YESAPERREQLSQELCHRLAIPLRTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE 267
            +E  P   +Q+ + LC      ++  +L  F    E S+LR H+      L++SA+    +R+   P    S + K RS +   E       Q SRY +EFEEL  + KGG+G V++ RNKLDG  YA+KKI++K        K+ REV  LA L HPN+V Y TAW+E
Sbjct:   80 HEPNPLHSKQVFKLLCQTF---IKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAK----ERVRQDPCQDNSYMQKIRSREIALEA------QTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVLAGLQHPNIVGYHTAWIE 235          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|32172458|sp|Q9BQI3.2|E2AK1_HUMAN (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1; AltName: Full=Heme-controlled repressor; Short=HCR; AltName: Full=Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; AltName: Full=Heme-regulated inhibitor; AltName: Full=Hemin-sensitive initiation factor 2-alpha kinase)

HSP 1 Score: 162.54 bits (410), Expect = 7.037e-41
Identity = 92/230 (40.00%), Postives = 134/230 (58.26%), Query Frame = 0

Query:  501 MLYLQMQLCDRTLRDWLDVRNAAA---CDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEAKEKQKLEDRV 725
            ML++QMQLC+ +L DW+  RN       D     Y +  ++   IF++++ GV YIH+ GI+HRDLKPRNIFL   + +V+IGDFGLA  D+    +     N    P          +HTS VGT  Y +PEQL+    + KSD+YSLG++L ELF PFGT MER++ +T +R G +P +  +  P  +K IQ +  +  S RPSA  LL++ LF +       L+ ++
Sbjct:  379 MLHIQMQLCELSLWDWIVERNKRGREYVDESACPYVM-ANVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRNGKRTP----------THTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQSELFQNSGNVNLTLQMKI 597          

HSP 2 Score: 114.39 bits (285), Expect = 3.980e-25
Identity = 76/232 (32.76%), Postives = 113/232 (48.71%), Query Frame = 0

Query:  102 YESAPERREQLSQELCHRLAIPLRTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE----------------PLLDSPTDLRRDRSSHSMQNMAAEVWS-VYSQPCSSPTSPAGDEDEE 313
            +E  P R  Q+ + LC      ++  +L  F    E S+LR H+      L++SA+    +R+   P    S + K RS +   E       Q SRY +EFEEL  + KGG+G V++ RNKLDG  YA+KKI++K     +  K+ REV  LA L HPN+V Y TAW+E                P L+  +D   DR    ++N  +   S ++++P        G+ D E
Sbjct:   80 HEPNPLRSRQVFKLLCQTF---IKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAK----ERVRQDPCEDISRIQKIRSREVALEA------QTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVIQPRADRAAIELPSLEVLSDQEEDREQCGVKNDESSSSSIIFAEPTPEKEKRFGESDTE 298          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|17375694|sp|Q9Z2B5.1|E2AK3_MOUSE (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 3; AltName: Full=PRKR-like endoplasmic reticulum kinase; AltName: Full=Pancreatic eIF2-alpha kinase; Flags: Precursor)

HSP 1 Score: 152.14 bits (383), Expect = 1.269e-36
Identity = 83/212 (39.15%), Postives = 121/212 (57.08%), Query Frame = 0

Query:  499 RAMLYLQMQLCDR-TLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAK-QDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLE 708
            +  LY+QMQLC +  L+DW++ R    C      + +     LHIF QI   V ++HS+G++HRDLKP NIF + ++ V++GDFGL    D      T  TP             +  +HT  VGT+ Y +PEQ+     + K DI+SLG+ILFEL +PF T MER + +T +R    PL F + YP+    +Q +LS  P+ RP A+D++E
Sbjct:  879 KVYLYIQMQLCRKENLKDWMNRR----CSLEDREHGV----CLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTP-----------MPAYATHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPFSTQMERVRILTDVRNLKFPLLFTQKYPQEHMMVQDMLSPSPTERPEATDIIE 1071          

HSP 2 Score: 75.8702 bits (185), Expect = 9.057e-13
Identity = 37/76 (48.68%), Postives = 51/76 (67.11%), Query Frame = 0

Query:  193 SRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLF-AKIFREVTTLAQLNHPNVVSYKTAWLE 267
            SRY  +FE +  + +GGFG+VF A+NK+D C YA+K+I L   + +L   K+ REV  LA+L HP +V Y  AWLE
Sbjct:  583 SRYLTDFEPIQCMGRGGFGVVFEAKNKVDDCNYAIKRIRLP--NRELAREKVMREVKALAKLEHPGIVRYFNAWLE 656          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|17374701|sp|Q9Z1Z1.1|E2AK3_RAT (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 3; AltName: Full=PRKR-like endoplasmic reticulum kinase; AltName: Full=Pancreatic eIF2-alpha kinase; Flags: Precursor)

HSP 1 Score: 148.673 bits (374), Expect = 1.410e-35
Identity = 82/212 (38.68%), Postives = 119/212 (56.13%), Query Frame = 0

Query:  499 RAMLYLQMQLCDR-TLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAK-QDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLE 708
            +  LY+QMQLC +  L+DW++ R    C      + +     LHIF QI   V ++HS+G++HRDLKP NIF + ++ V++GDFGL    D      T  TP             +  +HT  VGT+ Y +PEQ+     + K DI+SLG+ILFEL +PF T MER + +T +R    P  F + YP+    +Q +LS  P  RP A+D++E
Sbjct:  873 KVYLYIQMQLCRKENLKDWMNRR----CSMEDREHRV----CLHIFLQIAEAVQFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTP-----------MPAYATHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPQEHMMVQDMLSPSPMERPEATDIIE 1065          

HSP 2 Score: 76.2554 bits (186), Expect = 5.648e-13
Identity = 41/102 (40.20%), Postives = 61/102 (59.80%), Query Frame = 0

Query:  167 ARWSNVPKSRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLF-AKIFREVTTLAQLNHPNVVSYKTAWLE 267
            +++ +V    S    N+I+       SRY  +FE +  + +GGFG+VF A+NK+D C YA+K+I L   + +L   K+ REV  LA+L HP +V Y  AWLE
Sbjct:  555 SKYDSVSADNSDNSWNDIKHSGYV--SRYLTDFEPIQCMGRGGFGVVFEAKNKVDDCNYAIKRIRLP--NRELAREKVMREVKALAKLEHPGIVRYFNAWLE 652          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|296439367|sp|Q9NZJ5.3|E2AK3_HUMAN (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 3; AltName: Full=PRKR-like endoplasmic reticulum kinase; AltName: Full=Pancreatic eIF2-alpha kinase; Short=HsPEK; Flags: Precursor)

HSP 1 Score: 145.591 bits (366), Expect = 1.564e-34
Identity = 84/218 (38.53%), Postives = 121/218 (55.50%), Query Frame = 0

Query:  499 RAMLYLQMQLCDR-TLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAK-QDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSD 713
            +  LY+QMQLC +  L+DW++ R    C   +     + S+ LHIF QI   V ++HS+G++HRDLKP NIF + ++ V++GDFGL    D      T  TP             +   HT  VGT+ Y +PEQ+     + K DI+SLG+ILFEL +PF T MER + +T +R    P  F + YP     +Q +LS  P  RP A +++E  +F D
Sbjct:  881 KVYLYIQMQLCRKENLKDWMNGR----CTIEER----ERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTP-----------MPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFED 1079          

HSP 2 Score: 76.2554 bits (186), Expect = 6.384e-13
Identity = 37/76 (48.68%), Postives = 51/76 (67.11%), Query Frame = 0

Query:  193 SRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLF-AKIFREVTTLAQLNHPNVVSYKTAWLE 267
            SRY  +FE +  + +GGFG+VF A+NK+D C YA+K+I L   + +L   K+ REV  LA+L HP +V Y  AWLE
Sbjct:  587 SRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLP--NRELAREKVMREVKALAKLEHPGIVRYFNAWLE 660          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|68052253|sp|Q9LX30.2|GCN2_ARATH (RecName: Full=eIF-2-alpha kinase GCN2; AltName: Full=serine/threonine-protein kinase GCN2)

HSP 1 Score: 144.05 bits (362), Expect = 4.413e-34
Identity = 84/229 (36.68%), Postives = 122/229 (53.28%), Query Frame = 0

Query:  491 PQKGFQHDRAMLYLQMQLCDRTLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAK------QDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQ-FGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIR-EGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLETLF 711
            P++    +   LY+QM+ C RTLR   +  N             D     H+  QI+ G+A+IH QGIIHRD  P NIF    N+++IGDFGLAK       D     ST                 S    T   GT  Y APE  Q +  +++K+D+YSLG++ FEL+HPFGTAMER   +T ++ +G +PL ++  +P  +  ++ ++S  PS RPSA++LL+  F
Sbjct:  526 PEQDNNLESTYLYIQMEYCPRTLRQVFESYN-----------HFDKDFAWHLIRQIVEGLAHIHGQGIIHRDFTPNNIFFDARNDIKIGDFGLAKFLKLEQLDQDGGFSTD-------------VAGSGVDSTGQAGTYFYTAPEIEQDWPKIDEKADMYSLGVVFFELWHPFGTAMERHVILTNLKLKGELPLKWVNEFPEQASLLRRLMSPSPSDRPSATELLKHAF 730          

HSP 2 Score: 76.6406 bits (187), Expect = 5.002e-13
Identity = 40/82 (48.78%), Postives = 54/82 (65.85%), Query Frame = 0

Query:  192 NSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSP 273
            +SRY ++FEEL  + +GGFG V   +NKLDG  YAVKKI LK  +  + ++I REV TL++L H +VV Y  AW E  +  P
Sbjct:  418 SSRYLNDFEELKPLGQGGFGHVVLCKNKLDGRQYAVKKIRLKDKEIPVNSRIVREVATLSRLQHQHVVRYYQAWFETGVVDP 499          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. SwissProt
Match: gi|33860156|sp|Q9NIV1.2|E2AK3_DROME (RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase; AltName: Full=PRKR-like endoplasmic reticulum kinase; Short=DmPEK; Short=PEK; Short=PERK; Flags: Precursor)

HSP 1 Score: 134.806 bits (338), Expect = 3.742e-31
Identity = 90/241 (37.34%), Postives = 118/241 (48.96%), Query Frame = 0

Query:  499 RAMLYLQMQLCDR-TLRDWL-----DVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDL---------LETLFSDEAKEKQKLEDR 724
            +  LY+QMQLC + +LRDWL     + R A   D               IF QI+  V Y+H +G+IHRDLKP NIF S++ +++IGDFGL              PN   +   Q    S   HT  VGT  Y +PEQL     + K DIYSLG+I FEL   F T MER K +  +R+G  P  F   YP+    +Q +LS  P  RP    L         L  L S+   E+ +L +R
Sbjct:  926 KVYLYIQMQLCRKESLRDWLRDNRSETRAAHIGD---------------IFHQIVDAVDYVHLKGLIHRDLKPSNIFFSQDGQIKIGDFGLV-------TDMADIPNLVAKCGDQSGLPSCARHTQQVGTHLYMSPEQLLGQHYDYKVDIYSLGLIFFELHVYFSTEMERIKTLRSLRDGQYPKDFAVNYPQQYDLLQQMLSAQPEQRPQTKQLKSQLRNILQLPHLLSEGQSEQAELAER 1144          

HSP 2 Score: 68.9366 bits (167), Expect = 1.070e-10
Identity = 44/132 (33.33%), Postives = 68/132 (51.52%), Query Frame = 0

Query:  143 QHIFVRLVKSAQRSLTQRLADP------PAARWSNVPKSRSIQCINE-IREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE 267
            +H+ V+    A  + TQ L  P      P  R+S  P   + + I+E       +  SR++ +FE +  + +GGFG+VF A+NKLD   YA+K+I L   +     ++ RE  TLA   H N+V Y  +W E
Sbjct:  579 RHVPVQTAIEATEASTQALLGPVVPMQRPGNRFSFPPGQANQRTISESTTHSGEHYTSRFQSDFELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESSR-QRVLREARTLASCEHHNIVRYFHSWTE 709          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|1325321556|ref|XP_023342590.1| (eukaryotic translation initiation factor 2-alpha kinase 1-like [Eurytemora affinis])

HSP 1 Score: 299.671 bits (766), Expect = 1.337e-85
Identity = 230/729 (31.55%), Postives = 349/729 (47.87%), Query Frame = 0

Query:   86 RMPFVFHMVLHHLCSFYESAPERREQLSQELCHRLA-IPLRTPVLYEFPELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPK---SRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSPTDLRRDRSSHS-------MQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHL---EAISQSSG----IVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSAS--------GVDLDFYPPPKKT------------MPMNVTSIQELDELDSV----EENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASDDEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGF-QHDRAMLYLQMQLCDRTLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRNNEVQIGDFGLAKQDL--------SANVSTPHTPNDPLEPQHQLFHASE--KSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKV---PSLRPSASDLLETLFSD---EAKEKQKLEDRVKYLSDLVDRQREELQAKNDVIRSLKQASLQ 755
            ++  V   ++  L + YE   +RR+  ++E+C  L  + L  P  +   E+  LR+ Y   F RLV  A+  L       PAAR + +P          I+  + +++YQ SRY+ EF E   I  GGFG+V+RA+NKLD  +YAVKK+ +K C      KI REVT LA++NHPN+V YK AWLEP +   +    +  S++           ++E   +  +P +S   P   ++E  +       E  S+S      + F   +   D   R V + +      E + +++           D +F   P ++                VT ++ + E+       +  +  VIG   TP +++     +   +H+ +         KFW+     +D  SS          S +  P     P SR  L           EY+P     + +RA+L++QM++C  TLR WLD RN    D      SL++     +F QIL+  AY+HS+GI+HRD+KPRNIFL+   EV++GDFGLAK  L          +V   + P  P E +   F       +HTSGVGTQ Y +PEQL+   V+  SD+YSLGI+LFELFHPF T MER + +T +RE  +    LE        +Q+VL      P  RP+A  LL+ LFS    E  E+ KLE+    L ++V  Q + LQ K+ ++ + +   LQ
Sbjct:  201 KLSIVLISLVDQLAAAYEHDEQRRKLFTKEICESLVQMELVEPT-FLLEEMEGLRAQYSLAFYRLVGMARAGL-------PAARTTRLPALPGPDHYLAISSSKPENIYQFSRYKQEFVEEELIGGGGFGVVYRAKNKLDHGVYAVKKVFVKICKESTILKILREVTVLAKVNHPNIVGYKNAWLEPFVGEYSGSSDETQSYTSPSCLISSSTSSSEQVPISKKPATSSILPKPPQEESSMSIQFCDSETGSRSYNANYTVSFRSSESSMDTKERVVWNKEWEALEEELDCENSDFGDNLGNMRNDFNFKDDPIRSRGDSENINFISNQHKKVTLVETIVEMTGTPPEWDSEIERVIGKPQTPISKSTLHHTNPGTDHKKT-------RGKFWVGDQSSQDENSS----------SVVFLP---SGPGSRRELV----------EYSPNNSAPKLERAILFIQMEVCTITLRVWLDERN----DKWSEGSSLNIDECYKVFHQILNATAYLHSKGILHRDIKPRNIFLNNALEVKLGDFGLAKDVLLPTSKEKEEWDVDQGNVPETPSEIKDASFLPKHIHTAHTSGVGTQLYASPEQLKTSQVSTSSDMYSLGIVLFELFHPFCTDMERVRTLTSLRERRLENTRLE-----DDILQTVLQLTHPEPDRRPTAEMLLQGLFSKPEVEKMERNKLEEENLKLKEIVKLQDQRLQEKDKLLETQEAEILQ 882          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|1228002842|ref|XP_021933307.1| (eukaryotic translation initiation factor 2-alpha kinase 1-like [Zootermopsis nevadensis] >gi|646703581|gb|KDR12192.1| Eukaryotic translation initiation factor 2-alpha kinase 1 [Zootermopsis nevadensis])

HSP 1 Score: 279.641 bits (714), Expect = 3.151e-80
Identity = 210/688 (30.52%), Postives = 330/688 (47.97%), Query Frame = 0

Query:   89 FVFHMVLHHLCSFYESAPERREQLSQELCHRLAIPLRTPVLYEFPELSALRSHYQ----HIFV--RLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLYQNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSP-TDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFD-----DGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDLDFYPPPKKTMP--MNVTSIQELDELDSVEENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASDDEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQH-DRAMLYLQMQLCDRTLRDWLDVRNAAACDSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFLSRN-NEVQIGDFGLAK--QDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLETLF-----SDEAKEKQKLEDRVKYLSDLVDRQREELQAKNDVIRSLKQAS 753
             +   ++  LC    + P ++++L   +CH+L         Y   E   +RSHYQ    H+F   + V +   + T  L   P  R++    ++ + C            SRY  E+E+L FIA GGFG V++ARNKLDG  YAVKKI L+Y     F    REV  LA+LNHPN+VSYK AWLEP+  +  +    +  S    N     +   +               E+ + H      S  IVF      D +G+ D +   V+  +R   +++    S    +L      K+T+P   + T++   D++ S   ++   + +   P  +T          HE S             +SDD                           + +  +++      K   N +  +  + H + AMLY+QMQLC+RTLR WLD+RN+      Q S ++DV  ++ IF+QI+ GV YIHSQ I+H D+KP NIF++ N ++VQ+GDFGLA   Q  S +V+    P+     +H + H  E      +GT+ Y APEQL+ G  + KSD+YS+GI+LFEL  PF T MER K I  +R G+IP       P++++ I  ++S  PS RPSAS+L   L      +++A+        V++L  ++ +Q  E++     ++ L+ ++
Sbjct:   53 LLIQSLVEQLCKLLANTPGQQKRLYNVICHKLHQMNLIDQSYNVEEFEFMRSHYQRALFHLFTVAKSVTANNENETNVLLQLP--RYNLGMSNKLLPC----------DYSRYSTEYEQLEFIAHGGFGRVYKARNKLDGVEYAVKKICLQYRSVHGFLHSLREVKMLAKLNHPNIVSYKAAWLEPISSTTNSQFSEEDGSDKTDNALQHTYRTAA---------------EKKIYHYSTEDDSHSIVFKNSKSRDKEGLSDSSVG-VSIGERHDNNNQETSVSDHSNNLCIVSLQKRTLPPTHSYTNVGSADDVSSTTHSVMEPVCIGKIPSTKTS---------HESS------------TSSDD--------------------------SNVLVDKVMVKYQEAKKIANFWEIENPYAHFESAMLYVQMQLCERTLRQWLDIRNS------QDSPAVDVKQSIAIFQQIVSGVCYIHSQSIVHHDIKPSNIFVNHNLSQVQVGDFGLACCLQHSSDDVTLMVQPSS----EHPIMHKGE------IGTKLYAAPEQLR-GKCDSKSDLYSMGIVLFELLQPFSTDMERYKVIMQLRSGHIPSELTVTVPKLAQLIGRLVSASPSDRPSASELQLMLVPLIKETNDAESIDGENKTVQHLLAVIQKQNHEIEELRQQLQKLQTSA 648          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|1121910194|ref|XP_019476180.1| (PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 1 [Meleagris gallopavo])

HSP 1 Score: 259.225 bits (661), Expect = 5.969e-73
Identity = 202/624 (32.37%), Postives = 291/624 (46.63%), Query Frame = 0

Query:  125 RTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLY---QNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSPTDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDLDFYPPPKKTMPMNVTS--IQELDELDSVEENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASDDEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSS---HCLKAF-GNEYNPQKGFQHD-RAMLYLQMQLCDRTLRDWLDVRNAAAC----DSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEK---SHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEAKEKQKLEDRVK 726
            RT +L  F    E S +R  +      L+K+A R +     D   +R               I E+++    Q SRY +EF+E+  + KGG+G V++ RNKLDG  YA+KKI +K        K+ REV  LA L HPN+V Y TAW+E +    T   +D++   +Q++              P     D D      H +++   S I+F D    E+                    KS  G           T P N  S  +Q +D       +    I M    PNR + P                          + +ED  SS   R      +  K      HP S +L  S+    C + + GN+     GF+ + R MLY+QMQLC+ +L DW+  RN        D+    + +DVS    IFE++L GV YIHS G++HRD+KPRNIFL   +++V+IGDFGLA +DL              +   Q FH       +HTSGVGT  Y +PEQLQ    + KSD+YSLG+IL ELF PFGT MER++ IT +R G+IP  F + +P  +K ++ + S+V + RP+A+ L E+ LF         L+ +V+
Sbjct:   79 RTGLLSPFAFCDEFSTVRLQHNRAITELMKAANRQVLNGELDNGDSR--------------AIGEKEVLLEAQTSRYLNEFDEIARLGKGGYGQVYKVRNKLDGQFYAIKKINIKKATRRDCMKVLREVKVLAGLQHPNIVGYHTAWMEQV---QTACPKDKTILKLQSL--------------PLEQESDNDH----CHTQSVESGSSIIFADLTSQEE--------------------KSGDG-----------TYPRNQDSELVQNMDVRSDFTNSSSKEIRM---KPNRCESPV-------------------------ELQEDSVSSVDCR-----STDFKNDSSYGHPCSLDLDASAGSKSCTEEYSGNDVALCGGFEVEYRLMLYIQMQLCELSLWDWIAARNRRCNERTEDAAGPYHLVDVSWTTKIFEELLEGVCYIHSMGVMHRDIKPRNIFLHGSDHQVKIGDFGLACKDL------------LWDDADQWFHTGRINGLTHTSGVGTCLYASPEQLQGSDYDFKSDMYSLGVILLELFQPFGTEMERAEVITNLRNGHIPHNFYKKWPVQAKYVKLLTSQVSTERPTAAQLRESELFHTTEHVISNLQQKVR 591          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|971418671|ref|XP_015149615.1| (PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 [Gallus gallus])

HSP 1 Score: 256.529 bits (654), Expect = 1.483e-72
Identity = 199/619 (32.15%), Postives = 294/619 (47.50%), Query Frame = 0

Query:  125 RTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLY---QNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSPTDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDLDFYPPPKKTMPMNVTSIQELDELDSVEENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASD--DEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQHDRAMLYLQMQLCDRTLRDWLDVRNAAACDSGQSSYSL----DVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEK---SHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEAKEKQKLEDRVK 726
            RT +L  F    E S +R  +      L+K+A R +     D   +R               I E+++    Q SRY +EF+E+  + KGG+G V++ RNKLDG  YA+KKI +K        K+ REV  LA L HPN+V Y TAW+E +    T   +D++   +Q++  E               +GD+       H++++   S I+F D    E+++     D+ R        L++  G                  S+Q +D  +    +    I M    PNR + P   E+ E   S +   S   K   + D     D  +S G +    E S     L  +                F  EY         R MLY+QMQLC+ +L DW+  RN    +  + +  L    DVS  + IFE++L GV YIHS G++HRD+KPRNIFL   +++V+IGDFGLA +DL              +   Q FH       +HTSGVGT  Y +PEQLQ    + KSD+YSLG+IL ELF PFGT MER++ IT +R G+IP  F + +P  +K ++ + S+V + RP+A+ L E+ LF         L+ +V+
Sbjct:   19 RTGLLSPFAFCDEFSTVRLQHNRAITELMKAANRQVLNGELDNGDSR--------------AIGEKEVLLEAQTSRYLNEFDEIARLGKGGYGQVYKVRNKLDGQFYAIKKINIKKATRRDCMKVLREVKVLAGLQHPNIVGYHTAWMEHV---QTACPKDKTVLKLQSLPLE-------------QESGDDH-----CHIQSVESGSSIIFADLTSQEEKS----GDSTR--------LRNPDG-----------------ESVQNMDVRNDFTNSNSKEICM---KPNRCELPI--ELQEDSDSSVDCRSTDLKHDSSYDPPCSLDLDASAGSKSCTEECSGNDVALCGE----------------FEVEY---------RLMLYIQMQLCELSLWDWIAARNKRCNERTEDAAGLYHLVDVSWTMKIFEELLEGVCYIHSMGVMHRDIKPRNIFLHGSDHQVKIGDFGLACKDL------------LWDDADQWFHTERINGLTHTSGVGTCLYASPEQLQGSDYDFKSDMYSLGVILLELFQPFGTEMERAEVITNLRNGHIPHNFCKKWPVQAKYVKLLTSQVSTERPTAAQLRESELFHTTEHVISNLQQKVR 531          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|966649902|gb|KTF84812.1| (hypothetical protein cypCar_00026936 [Cyprinus carpio])

HSP 1 Score: 254.218 bits (648), Expect = 6.909e-71
Identity = 216/670 (32.24%), Postives = 304/670 (45.37%), Query Frame = 0

Query:   99 CSFYESAPERREQLSQELCHRLA-IPLRTPVLYEFPELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQD-LYQ--NSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLE---PLLDSPTDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDLDFYPPPKKTMPMNVTSIQELDELDSVEENLPHVIGMAATPPNR---TKFPPIDEIHEHEPSLLGGTSPSSKFWIASDDEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQHDRAMLYLQMQLCDRTLRDWLDVRNAAACD----SGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEKSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEAKE----KQKLEDRVKYLSDLVDRQREELQAKNDVIRS 748
            C  YE  P R   L + +  RLA + L +P+     E S +R  +   F  L+ +   SL      P   R+ +            +R +D L+Q   SRY  EFEE+  + KG +G VF+  NKLDG  YAVKKI++K    D   K+ REV  L+ L HPN+V Y TAW+E   P + +P                    S+ SQ C +   P   +                        G   + T   N +   F+HSE      + V L+       T               S EE     +G A  P N      F P   +   +P       P++K W +S   ED  S  G  L          P  S+        T +H ++                 MLY+QMQLC+R+L+DW+  RN+   +    S     S+D    L I ++IL GV YIHS GI+HRDLKPRNIFL      V+IGDFGLA ++L   +   H   + L    Q    ++ +HTSGVGT  Y APEQL+    + KSD+YS+G+I FELF PFGT MER   +  +R+G IP    + +P ++K I  + S  PS+RPSAS LL++ LFS         K+K++++ + +  L  RQ  EL+   + I S
Sbjct:   76 CFVYEHDPTRSRMLFKVIGQRLAAMNLLSPLAIS-DEFSTVRLQHNRAFTELLHATSSSLF-----PQEHRYLSTEGQN-------LRTKDGLFQAQTSRYLSEFEEIATLGKGSYGKVFKVTNKLDGQEYAVKKILIKKVTRDDCMKVLREVKVLSSLQHPNIVGYHTAWMEHIQPAVKNPK-------------------SLVSQKCPALEKPLQKD------------------------GCTQENTNSSNGSSIVFEHSEQAEAKENQVALESLSVKPST---------------SKEE-----MGHAVCPKNVRNPQNFVPC--VFLGKPRATVNKCPAAK-WDSSTLSEDDLSQNGLELNNNSSIDTDVPEWSE--------TQAHEVQF--------------HLMLYIQMQLCERSLKDWIQERNSRITEGLLMSVDPCESIDSEHALKILKKILEGVEYIHSHGIMHRDLKPRNIFLHGPECHVKIGDFGLACRNL---IMAEH---EQLPSSSQAGVNTDSTHTSGVGTFVYAAPEQLEGSHYDSKSDLYSIGVIAFELFQPFGTEMERVHTLGELRQGKIPNMLSKNWPLLAKYITLLTSTDPSMRPSASQLLQSDLFSTNDMVVHSLKRKIDEQEQEIVQL-KRQISELRISQNAIHS 637          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|971418675|ref|XP_015149617.1| (PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 1 isoform X3 [Gallus gallus])

HSP 1 Score: 250.366 bits (638), Expect = 8.049e-71
Identity = 180/547 (32.91%), Postives = 267/547 (48.81%), Query Frame = 0

Query:  191 QNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSPTDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDLDFYPPPKKTMPMNVTSIQELDELDSVEENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASD--DEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQHDRAMLYLQMQLCDRTLRDWLDVRNAAACDSGQSSYSL----DVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEK---SHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEAKEKQKLEDRVK 726
            Q SRY +EF+E+  + KGG+G V++ RNKLDG  YA+KKI +K        K+ REV  LA L HPN+V Y TAW+E +    T   +D++   +Q++  E               +GD+       H++++   S I+F D    E+++     D+ R        L++  G                  S+Q +D  +    +    I M    PNR + P   E+ E   S +   S   K   + D     D  +S G +    E S     L  +  +   L+                         LY+QMQLC+ +L DW+  RN    +  + +  L    DVS  + IFE++L GV YIHS G++HRD+KPRNIFL   +++V+IGDFGLA +DL              +   Q FH       +HTSGVGT  Y +PEQLQ    + KSD+YSLG+IL ELF PFGT MER++ IT +R G+IP  F + +P  +K ++ + S+V + RP+A+ L E+ LF         L+ +V+
Sbjct:   31 QTSRYLNEFDEIARLGKGGYGQVYKVRNKLDGQFYAIKKINIKKATRRDCMKVLREVKVLAGLQHPNIVGYHTAWMEHV---QTACPKDKTVLKLQSLPLE-------------QESGDDH-----CHIQSVESGSSIIFADLTSQEEKS----GDSTR--------LRNPDG-----------------ESVQNMDVRNDFTNSNSKEICM---KPNRCELPI--ELQEDSDSSVDCRSTDLKHDSSYDPPCSLDLDASAGSKSCTEECSGNDVALCGEFEVEYRLM-------------------------LYIQMQLCELSLWDWIAARNKRCNERTEDAAGLYHLVDVSWTMKIFEELLEGVCYIHSMGVMHRDIKPRNIFLHGSDHQVKIGDFGLACKDL------------LWDDADQWFHTERINGLTHTSGVGTCLYASPEQLQGSDYDFKSDMYSLGVILLELFQPFGTEMERAEVITNLRNGHIPHNFCKKWPVQAKYVKLLTSQVSTERPTAAQLRESELFHTTEHVISNLQQKVR 485          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|1201839053|ref|XP_021267285.1| (eukaryotic translation initiation factor 2-alpha kinase 1 isoform X4 [Numida meleagris] >gi|1201839055|ref|XP_021267286.1| eukaryotic translation initiation factor 2-alpha kinase 1 isoform X4 [Numida meleagris])

HSP 1 Score: 247.669 bits (631), Expect = 1.009e-69
Identity = 187/558 (33.51%), Postives = 264/558 (47.31%), Query Frame = 0

Query:  184 IREQDLY---QNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSPTDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDL--DFYPPPKKTMPMNVTSIQELDELDSVEENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASDDEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQHDRA-MLYLQMQLCDRTLRDWLDVRNAAAC----DSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEK---SHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEAKEKQKLEDRVK 726
            IRE+++    Q SRY +EF+E+  + KGG+G V++ RNKLDG  YA+KKI +K        K+ REV  LA L HPN+V Y TAW+E +    T   RD++   +Q              S P       D      H++++   S I+F D   +  Q  +  + T      SE    S   +D+  DF     K M M                            PNR + P   E+ E   S +   S   K            SS G    P     L A   SK              +  GN+      F+     ML++QMQLC+ +L DW+  RN        D+    + +DVS  + IFE+++ GV YIHS G++HRD+KPRNIFL   + +V+IGDFGLA +DL              +   Q FH       +HTSGVGT  Y +PEQLQ    + KSD+YSLG+IL ELF PFGT MER++ IT +R G IP  F + +P  +K ++ + S+V + RP+A+ L E+ LF         L+ +V+
Sbjct:   21 IREKEVLLEAQTSRYLNEFDEIARLGKGGYGQVYKVRNKLDGQFYAIKKINIKKATRRDCTKVLREVKVLAGLQHPNIVGYHTAWMEQV---QTACPRDKTILKLQ--------------SLPLEQESGNDR----CHIQSVESGSSIIFAD---LTSQEEKSGDSTYLRNLDSE----SGQNMDVRNDFTNSSSKEMCM---------------------------KPNRYELPV--ELQEDSVSSVDCRSTDLK----------NDSSYG----PHCSVDLDASAGSKSCTE----------ECSGNDVALCGEFEVGYCLMLHIQMQLCELSLWDWIVARNKRCNERTEDAAGPYHLVDVSWTMKIFEELIEGVCYIHSMGVMHRDIKPRNIFLHGSDRQVKIGDFGLACKDL------------LWDDTDQWFHTERINGLTHTSGVGTCLYASPEQLQGSDYDFKSDMYSLGVILLELFQPFGTEMERAEVITNLRNGRIPHNFYKKWPVQAKYVKLLTSQVSTERPTAAQLRESELFHTTEHVISNLQQKVR 485          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|1197334780|ref|XP_005020097.3| (eukaryotic translation initiation factor 2-alpha kinase 1, partial [Anas platyrhynchos])

HSP 1 Score: 249.595 bits (636), Expect = 1.648e-69
Identity = 175/527 (33.21%), Postives = 262/527 (49.72%), Query Frame = 0

Query:  191 QNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSPTDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDLDFYPPPKKTMPMNVTSIQELDELDSVEENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASDDEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQHDRAMLYLQMQLCDRTLRDWLDVRNAAACDSGQSSYS----LDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEK---SHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET 709
            Q SRY +EF+E+  + KGG+G VF+ RNKLDG  YA+KKI +K        K+ REV  LA L HPN+V Y TAW+E +    T   +D++   +Q+++ E               +G+        H++++   S I+F D    ED++            H    L++                 ++  S+Q +D    V+ +  +        PN  +FP    +   E S+    S S+ F         +  S  G   P     L    +SK                F  EY         R ML++QMQLC+ +L DW+  RN    +  + + S    +DV+  + IF+++L GV YIHS G++HRD+KPRNIFL   +  V+IGDFGLA +DL +         D ++   Q FH  +    +HTSGVGT  Y +PEQLQ    + KSD+YSLG+ILFELF PFGT MER + +T +R G+IP  F + +P  +K ++ + S+V + RP+A+ L E+
Sbjct:  128 QTSRYLNEFDEIARLGKGGYGQVFKVRNKLDGQFYAIKKINIKKATRRDCMKVLREVKVLAGLQHPNIVGYHTAWMEHV---QTLCPKDKTILKLQSLSLE-------------QESGNNH-----CHIQSVGSGSSIIFADLTSQEDKS------------HDSTCLRN-----------------LDSESVQNMD----VKNDFTNSNSKECMKPNGCEFP----LEVQEDSVSNVDSGSTDF---------KNHSPHG---PHCSLDLDVSTESKSCTEECSKNDVALCGEFEVEY---------RLMLHIQMQLCELSLWDWIVDRNKKYSERTEETASPYHLVDVNWTMKIFQELLEGVCYIHSMGVMHRDIKPRNIFLHGSDRRVKIGDFGLACKDLLS---------DDVD---QWFHTEQINGLTHTSGVGTCLYASPEQLQGSDYDFKSDMYSLGVILFELFQPFGTEMERVEVLTHLRNGHIPHTFYKNWPVQAKYVKLLTSQVSTERPTAAQLCES 563          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|1201839047|ref|XP_021267281.1| (eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 [Numida meleagris])

HSP 1 Score: 249.21 bits (635), Expect = 4.318e-69
Identity = 200/620 (32.26%), Postives = 293/620 (47.26%), Query Frame = 0

Query:  125 RTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLY---QNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSPTDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDL--DFYPPPKKTMPMNVTSIQELDELDSVEENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASDDEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQHDRAML-YLQMQLCDRTLRDWLDVRNAAAC----DSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASEK---SHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET-LFSDEAKEKQKLEDRVK 726
            RT +L  F    E S +R  +      L+K+A R +     D   +R               IRE+++    Q SRY +EF+E+  + KGG+G V++ RNKLDG  YA+KKI +K        K+ REV  LA L HPN+V Y TAW+E +    T   RD++   +Q++  E               +G++       H++++   S I+F D   +  Q  +  + T      SE    S   +D+  DF     K M M                            PNR + P   E+ E         S SS    ++D + D  SS G    P     L A   SK          S   +  GN+      F+    ++ ++QMQLC+ +L DW+  RN        D+    + +DVS  + IFE+++ GV YIHS G++HRD+KPRNIFL   + +V+IGDFGLA +DL              +   Q FH       +HTSGVGT  Y +PEQLQ    + KSD+YSLG+IL ELF PFGT MER++ IT +R G IP  F + +P  +K ++ + S+V + RP+A+ L E+ LF         L+ +V+
Sbjct:   94 RTGLLSPFAFCDEFSTVRLQHNRAITELMKAANREVLNGELDNGDSR--------------AIREKEVLLEAQTSRYLNEFDEIARLGKGGYGQVYKVRNKLDGQFYAIKKINIKKATRRDCTKVLREVKVLAGLQHPNIVGYHTAWMEQV---QTACPRDKTILKLQSLPLE-------------QESGNDR-----CHIQSVESGSSIIFAD---LTSQEEKSGDSTYLRNLDSE----SGQNMDVRNDFTNSSSKEMCMK---------------------------PNRYELPV--ELQE--------DSVSSVDCRSTDLKND--SSYG----PHCSVDLDASAGSK----------SCTEECSGNDVALCGEFEVGYCLMLHIQMQLCELSLWDWIVARNKRCNERTEDAAGPYHLVDVSWTMKIFEELIEGVCYIHSMGVMHRDIKPRNIFLHGSDRQVKIGDFGLACKDL------------LWDDTDQWFHTERINGLTHTSGVGTCLYASPEQLQGSDYDFKSDMYSLGVILLELFQPFGTEMERAEVITNLRNGRIPHNFYKKWPVQAKYVKLLTSQVSTERPTAAQLRESELFHTTEHVISNLQQKVR 606          

BLAST of eukaryotic translation initiation factor 2-alpha kinase 1 vs. nr
Match: gi|1201839049|ref|XP_021267282.1| (eukaryotic translation initiation factor 2-alpha kinase 1 isoform X2 [Numida meleagris])

HSP 1 Score: 248.054 bits (632), Expect = 8.629e-69
Identity = 196/602 (32.56%), Postives = 286/602 (47.51%), Query Frame = 0

Query:  125 RTPVLYEFP---ELSALRSHYQHIFVRLVKSAQRSLTQRLADPPAARWSNVPKSRSIQCINEIREQDLY---QNSRYRHEFEELGFIAKGGFGLVFRARNKLDGCLYAVKKIMLKYCDPDLFAKIFREVTTLAQLNHPNVVSYKTAWLEPLLDSPTDLRRDRSSHSMQNMAAEVWSVYSQPCSSPTSPAGDEDEERILRHLEAISQSSGIVFDDGQGIEDQATRRVNDTQRAFQHSEFELKSASGVDL--DFYPPPKKTMPMNVTSIQELDELDSVEENLPHVIGMAATPPNRTKFPPIDEIHEHEPSLLGGTSPSSKFWIASDDEEDRTSSRGGRLKPREESPLKAPLKSKHPISRELLTSSHCLKAFGNEYNPQKGFQHDRAML-YLQMQLCDRTLRDWLDVRNAAAC----DSGQSSYSLDVSLNLHIFEQILHGVAYIHSQGIIHRDLKPRNIFL-SRNNEVQIGDFGLAKQDLSANVSTPHTPNDPLEPQHQLFHASE---KSHTSGVGTQAYGAPEQLQFGVVNDKSDIYSLGIILFELFHPFGTAMERSKAITLIREGNIPLAFLEAYPRMSKKIQSVLSKVPSLRPSASDLLET 709
            RT +L  F    E S +R  +      L+K+A R +     D   +R               IRE+++    Q SRY +EF+E+  + KGG+G V++ RNKLDG  YA+KKI +K        K+ REV  LA L HPN+V Y TAW+E +    T   RD++   +Q++  E               +G++       H++++   S I+F D   +  Q  +  + T      SE    S   +D+  DF     K M M                            PNR + P   E+ E         S SS    ++D + D  SS G    P     L A   SK          S   +  GN+      F+    ++ ++QMQLC+ +L DW+  RN        D+    + +DVS  + IFE+++ GV YIHS G++HRD+KPRNIFL   + +V+IGDFGLA +DL              +   Q FH       +HTSGVGT  Y +PEQLQ    + KSD+YSLG+IL ELF PFGT MER++ IT +R G IP  F + +P  +K ++ + S+V + RP+A+ L E+
Sbjct:   94 RTGLLSPFAFCDEFSTVRLQHNRAITELMKAANREVLNGELDNGDSR--------------AIREKEVLLEAQTSRYLNEFDEIARLGKGGYGQVYKVRNKLDGQFYAIKKINIKKATRRDCTKVLREVKVLAGLQHPNIVGYHTAWMEQV---QTACPRDKTILKLQSLPLE-------------QESGNDR-----CHIQSVESGSSIIFAD---LTSQEEKSGDSTYLRNLDSE----SGQNMDVRNDFTNSSSKEMCMK---------------------------PNRYELPV--ELQE--------DSVSSVDCRSTDLKND--SSYG----PHCSVDLDASAGSK----------SCTEECSGNDVALCGEFEVGYCLMLHIQMQLCELSLWDWIVARNKRCNERTEDAAGPYHLVDVSWTMKIFEELIEGVCYIHSMGVMHRDIKPRNIFLHGSDRQVKIGDFGLACKDL------------LWDDTDQWFHTERINGLTHTSGVGTCLYASPEQLQGSDYDFKSDMYSLGVILLELFQPFGTEMERAEVITNLRNGRIPHNFYKKWPVQAKYVKLLTSQVSTERPTAAQLRES 588