BLAST of signal peptide peptidase-like 2b isoform x1 vs. L. salmonis genes
Match: EMLSAG00000004352 (supercontig:LSalAtl2s:LSalAtl2s229:218536:238930:1 gene:EMLSAG00000004352 transcript:EMLSAT00000004352 description:"maker-LSalAtl2s229-augustus-gene-2.24")

HSP 1 Score: 368.622 bits (945), Expect = 1.007e-111
Identity = 228/595 (38.32%), Postives = 328/595 (55.13%), Query Frame = 0

Query:   28 HWWNAFLPLVWFSQAMGAQSRFGLLVAVTEDMPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDD--LPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTTNIFVTALFHPDTKQKLLDIKRSHPHSKFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPM-PESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNEDWSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMGADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQF---EDDIKEEPLEASEDEHPIQSSANHPPMSESQAAG 616
            HW      L   + A    S+    + + E     ++CI Y P L  + S   ++  + +  L + T+ +TC+P+D+  + D   K+  +S  N  GNCSIA+R                      + Q   ALG+++D +V   F  +++   I V +    D   KL   + S   S F +Y  + +    D +I+ +F MA  TV LGS  SGY   N R           G V+ +S  G   ++  Q + P+S T+ QD  E  SV ITPL V+++V  M   L+ +YFF +Y++Y +IG++++ S+ +TY+ FEP+VM SY      PT   P+   + C   ME RQ LLL F IA+S +W ++R E W WI+QD LGIL  L +++ +RLPS KICT+LLS+L  YDIFFVFITP FTK+G+SVMV+VA+G D+GE  P+VL VPR+       C+    +LG GDI +PGLLVSYC++FD+  E  CKIYW  AN+ Y + LI T +SL L  +AQPALLY+VP TL+P  +VA  RGEF   W G  F     D  +E     E+  P + S +    S+ + AG
Sbjct:  397 HWXLVASILCVLAFASSVDSKLETRLGILETSGGDYYCISYIPSLSKIPSK-SDSQTFQISSLINFTHVDTCNPNDESVVTDSKNKIPFISGNNDLGNCSIAERAK--------------------NLQDSGALGILSDGTVHGEFTPNQFKITIPVISAMKNDI-YKLSTTESSE--STFRIYHLDHS-FLFDPAILALFLMATGTVLLGSFLSGYFSKNKR----------KGFVSGES--GDHTAAQSQTLQPQSITNIQD--EDASVSITPLKVIIYVIFMSCFLVTIYFFSSYIIYGLIGLYILLSITSTYSIFEPLVMCSYSKCSGLPTCFFPK---WKC---MEFRQILLLVFCIALSVVWFIYRKEPWIWIIQDFLGILICLLLMRDVRLPSLKICTLLLSLLLFYDIFFVFITPYFTKDGESVMVDVALGGDSGETFPIVLIVPRM-LSLKKICYSNVMMLGLGDIALPGLLVSYCYSFDVHMEKPCKIYWICANIGYIIGLIITDVSLLLSGAAQPALLYLVPCTLVPTFLVALCRGEFKTIWNGGPFVRSYPDTLDEQNPPDENLTPTRDSYDRSANSQDECAG 945          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. L. salmonis genes
Match: EMLSAG00000011468 (supercontig:LSalAtl2s:LSalAtl2s790:54002:55114:-1 gene:EMLSAG00000011468 transcript:EMLSAT00000011468 description:"augustus_masked-LSalAtl2s790-processed-gene-0.7")

HSP 1 Score: 83.9593 bits (206), Expect = 1.179e-17
Identity = 66/204 (32.35%), Postives = 106/204 (51.96%), Query Frame = 0

Query:  385 SIAISTI---WCVFRNEDWSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMGADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPF-TLIPIAIVATIRGEFMEFWTGDQFED 584
            ++A+S++   W +F+     WI  +I G+ F++N ++ L L +     ILL  LF YD+F+VF        G +VMV VA    T  + P+ L  P+   +         ++LG GDI++PG+ V+    +D     +   Y+ T  + Y L L+ T   +   + AQPALLY+ P  T IPI +VA IRG+    +   Q++D
Sbjct:  170 ALALSSVLGXWYLFKKH---WIANNIFGLAFAINGIELLHLNNVMTGCILLGGLFFYDVFWVF--------GTNVMVTVA----TNFEAPIKLVFPQDLMEKGVFGASNMAMLGLGDIVIPGIFVALLLRYDRSLNRKSNFYFYTCFIAYVLGLLTTIGVMHTFKHAQPALLYLSPACTGIPI-LVALIRGDVKSMF---QYKD 354          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|97180302|sp|Q3TD49.2|SPP2B_MOUSE (RecName: Full=Signal peptide peptidase-like 2B; Short=SPP-like 2B; Short=SPPL2b; Flags: Precursor)

HSP 1 Score: 341.273 bits (874), Expect = 3.155e-108
Identity = 225/592 (38.01%), Postives = 322/592 (54.39%), Query Frame = 0

Query:   48 RFGLL--VAVTEDMPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCS-PDDDLPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDS-VPIRFNASEYT-TNIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSSANHPPMSESQAAGSSSMARNKKAQEE 629
             FG+L  V+ T     + +CI Y P+  +L  ++    +  L  L DL+  + CS  D    D   ++ALV+     GNC+  ++V + +                      H L +++ +  VP   N ++Y   +I V  L H D    L DI R       + +Y P E    +D ++++IF MAV TV +G  W+G   H+++ KY +                +RD       PE Q       E  +V +TP+ + +FV   C ML+LLY+F++ LVY+IIG+F +AS    Y+C  P V       P C T R+P  NL       + R  LL  F + +S +W +FRNED W+W+LQD LGI F L MLKT+RLP+FK CT+LL +LF+YDIFFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  +IY+    + Y L L+ TF++L LM+  QPALLY+VP TL+    VA  R E   FWTG  F  D  + P  A++   P ++  +    S S+   S  +A++  + EE
Sbjct:   20 EFGVLRVVSQTSRTRSRDYCILYNPQWAHLPHDLS---KVSLLKLRDLSTTQLCSYLDVPAEDFTNQIALVA----RGNCTFYEKVRLAQ------------------GSGAHGLLIVSKEKLVPPGGNKTQYEEISIPVALLSHRD----LQDIFRRFGREVMVALYAPSEP--VMDYNMVIIFVMAVGTVAIGGYWAG--SHDVK-KYMKH---------------KRDDG-----PEKQ-------EDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPFVR----KLPFC-TCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGIFRNEDQWAWVLQDTLGIAFCLYMLKTIRLPTFKACTLLLLVLFIYDIFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLLTSCTVALWRRELGAFWTGSGFAKDAPQTPWAATQGPVPPKAVGS----SLSEQPPSEELAKSPLSTEE 540          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|81883236|sp|Q5PQL3.1|SPP2B_RAT (RecName: Full=Signal peptide peptidase-like 2B; Short=SPP-like 2B; Short=SPPL2b; Flags: Precursor)

HSP 1 Score: 339.732 bits (870), Expect = 1.003e-107
Identity = 227/600 (37.83%), Postives = 325/600 (54.17%), Query Frame = 0

Query:   48 RFGLLVAVTED--MPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSP-DDDLPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDS-VPIRFNASEYT-TNIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFED-----------DIKEEPLEASEDEHPIQSSANHPPMSESQAAGSSSMARNKKA 626
             FG+L  V +      + +CI Y P+  +L  ++    +  L  L DL+  + CS  D  + D   ++ALV+     GNC+  ++V + +                      H L +++ +  VP R N ++Y   +I V  L H D    L DI R   H   + +Y P E    +D ++++IF MAV TV LG  W+G   H+++ KY +                +RD      +PE Q       E  +V +TP+ + +FV   C ML+LLY+F++ LVY+IIG+F +AS    Y+C  P V       P C T R+P  NL       + R  LL  F + +S +W VFRNED W+W+LQD LGI F L ML+T+RLP+FK CT+LL +LFVYDIFFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  +IY+    + Y L L+ TF++L LM   QPALLY+VP TL+    VA  R E   FWTG  F D            +  + ++AS  E P        P++ ++ AG++  A++  +
Sbjct:   20 EFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLN---KVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVA----RGNCTFYEKVRLAQ------------------GSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRD----LQDIFRRFGHEVMVALYAPSEP--VMDYNMVIIFIMAVGTVALGGYWAG--SHDVK-KYMKH---------------KRDD-----VPEKQ-------EDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVR----KLPFC-TCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKACTLLLLVLFVYDIFFVFITPYLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFADAPQTPWAAPQGPVPPKDVDASLSEQPRGEELAQSPLA-TEEAGATDPAKDPDS 551          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|82125332|sp|Q5F383.1|SPP2B_CHICK (RecName: Full=Signal peptide peptidase-like 2B; Short=SPP-like 2B; Short=SPPL2b; Flags: Precursor)

HSP 1 Score: 339.732 bits (870), Expect = 1.671e-107
Identity = 218/560 (38.93%), Postives = 312/560 (55.71%), Query Frame = 0

Query:   62 QHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLPDLG--QKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTT-NIFVTALFHPDTKQKLLDIKRSHPHS-KFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSSANHPPMSESQ 613
            + +CI +  +  +L  ++ +A    L  L D T    CSP D +PD G   ++ +V      GNC+  ++V + ++     +L  S                  +  VP   N S+Y   +I V  L + D    +LDI +S   S K  +Y P E    LD ++++IF MAV TV +G  W+G    +++ +Y +                +RD   E+            HE  +V +TP+ + +FV   C+ML+LLYFF+++LVY+IIG+F +A+ I  Y+C  P V      FP     RIP  NL       ++R  LL  F I++S +W VFRNED W+W+LQD LGI F L MLKT+RLP+FK CT+LL +LFVYD+FFVFITP  TK G+S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  ++Y+    + Y + L+ TF++L LM+  QPALLY+VP TLI    VA  R E   FWTG  F  D+ + PL  +    P     ++ P S+ +
Sbjct:   38 KDYCILFNSQWAHLPHDLGKA---SLLQLQDQTASVLCSPSD-VPDGGFNNRIPMV----MRGNCTFYEKVRLAQINGARGLLIVSR-----------------ERLVPPGGNRSQYEEIDIPVALLSYSD----MLDIVKSFGRSVKGAMYAPNEP--VLDYNMVIIFVMAVGTVAIGGYWAG--SRDVKERYMKH---------------KRDDGAEK------------HEDETVDVTPIMICVFVVMCCSMLVLLYFFYDHLVYVIIGIFCLAASIGLYSCLSPFVR----RFPL-GKCRIPDNNLPYFHKRPQVRILLLAVFCISVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKGCTLLLLVLFVYDVFFVFITPFLTKTGESIMVEVAAGPSDSATHEKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RVYFVACTIAYGIGLLVTFVALALMQMGQPALLYLVPCTLITSFSVALWRKELAMFWTGSGFAKDLPQPPLVIASVNCPQLPKDSNVPASQQE 531          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|97537015|sp|Q8TCT7.2|SPP2B_HUMAN (RecName: Full=Signal peptide peptidase-like 2B; Short=SPP-like 2B; Short=SPPL2b; AltName: Full=Intramembrane protease 4; Short=IMP-4; AltName: Full=Presenilin homologous protein 4; Short=PSH4; AltName: Full=Presenilin-like protein 1; Flags: Precursor)

HSP 1 Score: 305.064 bits (780), Expect = 3.480e-94
Identity = 209/560 (37.32%), Postives = 300/560 (53.57%), Query Frame = 0

Query:   62 QHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLPDLG--QKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLI---ADDSVPIRFNASEYTTNIFVTALFHPDTKQKLLDI-KRSHPHSKFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVM-WSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSSANHPPMS 610
            + +CI Y P+  +L  ++ +A       L + T    CS   DLP  G   ++ LV+     GNC+  ++V +                     Q   A GL+    +  VP   N ++Y       AL    + + +LDI  R     +  +Y P+E    LD ++++IF MAV TV +G  W+G    +++ +Y +                +RD       PE Q       E  +V +TP+   +FV   C+ML+LLY+F++ LVY++IG+F +AS    Y+C  P V    +G        RIP  +L       + R  LL  F +A+S +W VFRNED W+W+LQD LGI F L MLKT+RLP+FK CT+LL +LF+YDIFFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  ++Y+    + Y + L+ TF++L LM+  QPALLY+VP TL+    VA  R E   FWTG  F   +   P   +  + P     +  P+S
Sbjct:   42 KDYCILYNPQWAHLPHDLSKA---SFLQLRNWTASLLCS-AADLPARGFSNQIPLVA----RGNCTFYEKVRLA--------------------QGSGARGLLIVSRERLVPPGGNKTQYDEIGIPVALL---SYKDMLDIFTRFGRTVRAALYAPKEP--VLDYNMVIIFIMAVGTVAIGGYWAG--SRDVKKRYMKH---------------KRDDG-----PEKQ-------EDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFG------KCRIPNNSLPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLS 532          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|341941738|sp|Q9JJF9.2|SPP2A_MOUSE (RecName: Full=Signal peptide peptidase-like 2A; Short=SPP-like 2A; Short=SPPL2a; AltName: Full=Intramembrane protease 3; Short=IMP-3; AltName: Full=Presenilin-like protein 2; Flags: Precursor)

HSP 1 Score: 286.574 bits (732), Expect = 5.177e-88
Identity = 186/548 (33.94%), Postives = 293/548 (53.47%), Query Frame = 0

Query:   61 DQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSV--PIRFNASEYTTNIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMGA-DTGEQLPMVLRVPRL-NYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQS 602
             + +C+ Y      L S+++ A    L    +LT    C   D  PD  +  A+V      G C   ++  + +                   +   A  LIA++SV  P   N S +     VT L    T++   D+K +      + +Y P       D ++++IF +AVFTV LG  WSG  +                  N +S     D        E++    D+     +  +PL VV+FV   C M++LLYFF+ +LVY++I +F +AS ++ Y C   ++       PC       +C +  C  N+++    L    I+++ +W VFRNED W+WILQDILGI F LN++KT++LP+F  C ILL +L +YD+FFVFITP  TKNG+S+MVE+A G  +  E+LP+V+RVP+L  Y  +  C +P S+LGFGDI+VPGLL++YC  FD+  +T   IY+ ++ + YA+ +I TF+ L +M++ QPALLY+VP TLI +++VA  R E  +FW G  ++  + +    ++ +E+P+ +
Sbjct:   41 SKDYCMYYNNNWTRLPSSLENATSLSL---MNLTGTALCHLSDIPPDGIRNKAVVVHW---GPCHFLEKARIAQ-------------------EGGAAALLIANNSVLIPSSRNKSTFQN---VTVLIAVITQKDFKDMKETLGDDITVKMYSPSWPN--FDYTLVVIFVIAVFTVALGGYWSGLIELE----------------NMKSVEDAEDR-------ETRKKKDDY-----LTFSPLTVVVFVVICCIMIVLLYFFYRWLVYVMIAIFCIASSMSLYNCLSALI----HRMPC------GQCTILCCGKNIKVSLIFLSGLCISVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTMKLPNFMSCVILLGLLLIYDVFFVFITPFITKNGESIMVELAAGPFENAEKLPVVIRVPKLMGYSVMSVCSVPVSVLGFGDIIVPGLLIAYCRRFDV--QTGSSIYYISSTIAYAVGMIITFVVLMVMKTGQPALLYLVPCTLITVSVVAWSRKEMKKFWKGSSYQ--VMDHLDYSTNEENPVTT 516          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|25008981|sp|Q8TCT8.2|SPP2A_HUMAN (RecName: Full=Signal peptide peptidase-like 2A; Short=SPP-like 2A; Short=SPPL2a; AltName: Full=Intramembrane protease 3; Short=IMP-3; AltName: Full=Presenilin-like protein 2; Flags: Precursor)

HSP 1 Score: 265.774 bits (678), Expect = 5.093e-80
Identity = 190/552 (34.42%), Postives = 297/552 (53.80%), Query Frame = 0

Query:   62 QHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSV--PIRFNASEY-TTNIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTK-HNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIP--RCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMGA-DTGEQLPMVLRVPRLNY-DPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSS 603
            + +C+ Y P    L S ++ A    L    +LT+   C+  D +P +G K   V      G+C   ++  + +                   +      L+ ++SV  P   N SE+    I +  + + D +    D+ ++   +  + +Y P       D ++++IF +AVFTV LG  WSG  +  NL+       ++ T                     E +   +   E ++   +PL VV+FV   C M++LLYFF+ +LVY++I +F +AS ++ Y C   ++             +IP  +C +     NME+R   L    IA++ +W VFRNED W+WILQDILGI F LN++KTL+LP+FK C ILL +L +YD+FFVFITP  TKNG+S+MVE+A G     E+LP+V+RVP+L Y   +  C +P SILGFGDI+VPGLL++YC  FD ++     IY+ ++ + YA+ +I TF+ L LM+  QPALLY+VP TLI  ++VA  R E  +FW G+ ++  + +    A+ +E+P+ S 
Sbjct:   39 KDYCMLYNPYWTALPSTLENATSISL---MNLTSTPLCNLSD-IPPVGIKSKAVVVP--WGSCHFLEKARIAQ-------------------KGGAEAMLVVNNSVLFPPSGNRSEFPDVKILIAFISYKDFR----DMNQTLGDNITVKMYSPSWPN--FDYTMVVIFVIAVFTVALGGYWSGLVELENLK-------AVTT---------------------EDREMRKKKEEYLT--FSPLTVVIFVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIH------------KIPYGQCTIACRGKNMEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFD-VQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQ--MMDHLDCATNEENPVISG 514          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|166215587|sp|A2A6C4.1|SPP2C_MOUSE (RecName: Full=Signal peptide peptidase-like 2C; Short=SPP-like 2C; Short=SPPL2c; AltName: Full=Intramembrane protease 5; Short=IMP-5; Flags: Precursor)

HSP 1 Score: 268.855 bits (686), Expect = 1.818e-79
Identity = 196/605 (32.40%), Postives = 308/605 (50.91%), Query Frame = 0

Query:   45 AQSRFGLLVAVTEDMPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLT---NEETCSPDDDLPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTTNIFVTALFHPDTKQKLLDIKRSHPHS----KFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVV----MWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG-ADTG--EQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSSANHPPMSESQAAGSSSMARNKKAQEEDVHQL 634
            A+  +GL+  V+++   + +C+ Y  +  NL  ++  AP   L D T      +E++     D     + +   +   T GNCS   +  + + +    +L  S      + Q    +    D S P           I V  L + D    +LDI  SH +     +  ++ P   E   D ++ +IF +AV TV  G  W+G  + N   K +R+ +   GG+     N ++  + E+     +    D  E   +  TP      V   C++++LLYFF++  VY++IG+F + +    Y+C  P++    +W Y      P  R+          ++     LL      ++ +W + RNED W+W+LQD LG+ + L +L+ +RLP+FK CT+ L  L  +D+FFVFITPLFTK G+S+MVEVA G AD+   E+LPMVL+VPRL++  L  C  P+SILGFGDI+VPG LV+YCH FD+  ++R ++Y+    + YA+ L+ TF+++ LM+  QPALLY+V  TL+    VAT R EF  FWTG Q    I  EP+       P  +SA    M    A  S +  R ++A + +   L
Sbjct:   26 ARGEYGLVRVVSKNW-SKDYCVLYSSDYVNLPRDLHHAPLLSLHDGTKTPWCPDEDSFHQAQDSSPRQRPLHQTTTMVTRGNCSFYAKGWLAQDQGAQGLLIVSRAR---NQQCSDTISKPQDPSKPWP------ALTIPVAVLRYTD----MLDIV-SHTYGDTDVRVAMFAP--LEPVTDYNMAIIFILAVGTVAAGGYWAGLMEAN---KLQRRQAQRGGGLG--GHNQQQTVAAER---SQRAWEDDDFEDAPMDFTPAMTGAVVTMSCSIMILLYFFYDCFVYVMIGIFSLGASTGLYSCLAPILCHLPLWRYQWV--LPGQRV----------SVTWPLLLLAGLCAMVTVLWVIHRNEDHWAWLLQDTLGVAYCLFVLRRVRLPTFKNCTLFLLALLAFDVFFVFITPLFTKTGESIMVEVASGPADSSSHERLPMVLKVPRLSFSALTLCNQPFSILGFGDIVVPGFLVAYCHRFDMQVQSR-QVYYMACTVAYAVGLLVTFVAMILMQMGQPALLYLVSSTLLTSLAVATCRQEFTLFWTG-QGRAKIPAEPV-----AQPCIASAVGSKMKLEDAKDSRTTNRFEQAVDGESGDL 586          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|269849676|sp|Q8IUH8.3|SPP2C_HUMAN (RecName: Full=Signal peptide peptidase-like 2C; Short=SPP-like 2C; Short=SPPL2c; AltName: Full=Intramembrane protease 5; Short=IMP-5; Flags: Precursor)

HSP 1 Score: 211.46 bits (537), Expect = 2.398e-58
Identity = 180/554 (32.49%), Postives = 278/554 (50.18%), Query Frame = 0

Query:   45 AQSRFGLLVAVTEDMPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLPDLGQ-------KVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHA----LGLIADDSVPIRFNASEYTTNIFVTALFHPDTKQKLLDIKRSHPHSKFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRI---PRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGD 580
            A  ++G+   V+E+   + +CI +  +   L  ++  AP   L  L D T    C P +D P   Q        +   +A    GNCS   +  + + +    +L  S V       T  A       +AD ++P+              A+ H      +L   R     +  +Y P E    +D ++++IF +AV TV  G  W+G T+ N RL+  R       G ++Q                ++ + ++ +E + V  TP    + V   C+++LLLYFF+++ VY+ IG+F + + I  Y+C  P+V        C  ++R    P  +L+  +    L    L A  I     W  +RNED W+W+LQD LGI + L +L  +RLP+ K C+  L  L  +D+FFVF+TP FTK G+S+M +VA+G   + + E+LPMVL+VPRL    L  C  P+SILGFGDI+VPG LV+YC  FD+   +R +IY+    + YA+ L+ TF+++ LM+  QPALLY+V  TL+    VA  R E   FWTG 
Sbjct:   20 AGGKYGVAHVVSENW-SKDYCILFSSDYITLPRDLHHAP---LLPLYDGTKAPWC-PGEDSPHQAQLRSPSQRPLRQTTAMVMRGNCSFHTKGWLAQGQGAHGLLIVSRVSDQQCSDTTLAPQDPRQPLADLTIPV--------------AMLHYADMLDILSHTRGEAVVRVAMYAPPEP--IIDYNMLVIFILAVGTVAAGGYWAGLTEAN-RLQRRRARRGGGSGGHHQLQE----------AAAAEGAQKEDNEDIPVDFTPAMTGVVVTLSCSLMLLLYFFYDHFVYVTIGIFGLGAGIGLYSCLSPLV--------CRLSLRQYQRPPHSLWASLPLPLLLLASLCATVI---IFWVAYRNEDRWAWLLQDTLGISYCLFVLHRVRLPTLKNCSSFLLALLAFDVFFVFVTPFFTKTGESIMAQVALGPAESSSHERLPMVLKVPRLRVSALTLCSQPFSILGFGDIVVPGFLVAYCCRFDVQVCSR-QIYFVACTVAYAVGLLVTFMAMVLMQMGQPALLYLVSSTLLTSLAVAACRQELSLFWTGQ 529          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|75269859|sp|Q53P98.1|SIPL2_ORYSJ (RecName: Full=Signal peptide peptidase-like 2; Short=OsSPPL2; Flags: Precursor)

HSP 1 Score: 184.496 bits (467), Expect = 9.588e-50
Identity = 137/450 (30.44%), Postives = 231/450 (51.33%), Query Frame = 0

Query:  154 QTHHALGL--IADDSVPIRFNASEYTTNIFVT---ALFHPDTKQKLLDIKRSHPHSKFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCC-PTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNEDWSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMGADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIY-----WSTANLFYALSLIATFISLFLMES-AQPALLYIVPFTLIPIAIVATIRGEFMEFWT-GDQFEDDIKEEP 590
            QT  A+GL  I D+    +   S+  T+I VT    +      +K+  +       +  +Y P      +D S   ++ MA+ T+   SLW+ +                   V  +  + R +    +  P S T+N++  E   +      V + V  +  +LLL YF  ++ V+++I +F +  +   + C   V + +     C   T+++P    F  V+ + +   L++ F    + +W V+R+  ++WI QDILGI   + +L+  RLP+ ++ + LLS  FVYD+F+VFI+PL     +SVM+ VA G ++GE +PM+LR+PR  +DP    W  Y ++GFGDI+ PGLLV++ + FD  R ++  ++     W T    YA+ L  T+++LFLM+   QPALLY+VP TL  I I+   RGE  + W  G    +++ +EP
Sbjct:  126 QTGGAVGLLVINDNEELYKMVCSDNDTSINVTIPVVMIPQSAGKKMKGLLDQGARLEVQLYSPNRP--VVDLSACFLWIMAIGTIVCASLWTEF-------------------VACEQVDERYNQLTRKDGPNSGTTNREDKEIFEISAKGAIVFILVASV-FLLLLFYFMSSWFVWLLIVLFCIGGIEGMHVCL--VTLLTRICKDCGQKTVQLP---FFGEVLTLSV---LIVPFCTIFAILWAVYRHASFAWIGQDILGICLMITVLQMARLPNIRVASALLSAAFVYDVFWVFISPLIFH--ESVMIAVARGDNSGEAIPMLLRIPRF-FDP----WGGYDMIGFGDIIFPGLLVAFSYRFD--RASKRGLFNGYFLWLTVG--YAVGLFLTYLALFLMDGHGQPALLYLVPCTLGLIVILGWFRGELHDLWNYGRSQTENLVDEP 534          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. SwissProt
Match: gi|75264901|sp|Q9MA44.1|SIPL5_ARATH (RecName: Full=Signal peptide peptidase-like 5; Short=AtSPPL5; Flags: Precursor)

HSP 1 Score: 163.696 bits (413), Expect = 2.968e-42
Identity = 124/394 (31.47%), Postives = 202/394 (51.27%), Query Frame = 0

Query:  197 IKRSHPHSK---FIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFN-YLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRC---NLFICVI-NMELRQFLLLAFSIAISTIWCVFRNEDWSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMGA-DTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKI---YWSTANLFYALSLIATFISLFLMES-AQPALLYIVPFTLIPIAIVATIRGEFMEFW 577
            +K+S   +K    ++Y P+     +D +++ ++ M+V TV + S+WS  T      +   +LS P    N  ++ G                     E  ++ I+ +  V+FV    T L+LL+FF + + + I+   FV+  +   +     ++           T R  +C   NL + ++ N  +   ++L F   ++ +W + R    +W  QDI GI   +N+L+  RLP+ ++ TILL   F YDIF+VFI+PL  K  +SVM+ VA G+ DTGE +PM+LR+PRL+ DP    W  Y+++GFGDIL PGLL+ +   FD  +E    +   Y+      Y L L  T++ L++M    QPALLY+VP TL    I+  +R E  + W
Sbjct:  167 LKKSIMQNKKVELLLYAPKSP--IVDYAVVFLWLMSVGTVFVASVWSHVTSPKKNDEQYDELS-PKKSSNVDATKG-------------------GAEEETLDISAMGAVIFVISASTFLVLLFFFMSSWFILILTIFFVIGGMQGMHNINVTLI-----------TRRCSKCGQKNLKLPLLGNTSILSLVVLLFCFVVAILWFMNRKTSHAWAGQDIFGICMMINVLQVARLPNIRVATILLCCAFFYDIFWVFISPLIFK--QSVMIAVARGSKDTGESIPMLLRIPRLS-DP----WGGYNMIGFGDILFPGLLICFIFRFD--KENNKGVSNGYFPWLMFGYGLGLFLTYLGLYVMNGHGQPALLYLVPCTLGITVILGLVRKELRDLW 518          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|1325277202|ref|XP_023323238.1| (signal peptide peptidase-like 2B [Eurytemora affinis])

HSP 1 Score: 375.17 bits (962), Expect = 1.316e-121
Identity = 201/382 (52.62%), Postives = 266/382 (69.63%), Query Frame = 0

Query:  170 RFNASEYTTNIFVTALFHPDTKQKLLDIKRSHPHSKFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNEDWSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMGADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPA 551
            +FNAS Y  ++   +L     ++K+L +++++P ++F ++     +   D S ++IF MAV TV +GSLWSGY K NLR++ E  L     GVN    +  RD  G +    SQ       E +SVR++PL ++ FV  MC+ML+LLYFFFN LVY+I+ MF +AS +A Y+CFEP+VM +Y A P  P +R+PR NL+IC +++E+RQ LLL  S+  + +W +FR  DWSWILQD LGI+FS+NMLK LRLPS KICT LLS LF YDIFFVFITPLF K+GKSVMVEVA G  + EQLPMVLRVP LN+DP +     YS+LGFGDILVPGLL+++CH FDL+  T CKIYW  + + Y L L+ATFISLFL+    P+
Sbjct:   10 KFNASLYNISVPFGSLVEKTAREKILTMQKNYPDAQFYMF---SNDVNFDLSTLVIFLMAVSTVTIGSLWSGYAKQNLRIRKETGLE----GVN----SRMRDEEGIK----SQDGGGGEEEEISVRVSPLLIMFFVFCMCSMLVLLYFFFNQLVYVIMAMFCIASSLAMYSCFEPLVMATY-ALPL-PVLRLPRINLYICRLDLEIRQLLLLLISLTTAIVWFIFRKTDWSWILQDFLGIMFSINMLKVLRLPSLKICTCLLSALFFYDIFFVFITPLFMKDGKSVMVEVATGHSSDEQLPMVLRVPHLNHDPCYT--YTYSLLGFGDILVPGLLLAFCHGFDLMIGTPCKIYWVLSCICYTLGLVATFISLFLILFLSPS 372          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|1238878919|ref|XP_022252689.1| (signal peptide peptidase-like 2B isoform X2 [Limulus polyphemus])

HSP 1 Score: 367.081 bits (941), Expect = 8.597e-116
Identity = 227/594 (38.22%), Postives = 326/594 (54.88%), Query Frame = 0

Query:   34 LPLVWFSQAMGAQSRFGLLVAVTEDMPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCS--PDDDLPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTTNIFVTALFHPDTKQKLLDIKRSHPHSKFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVM-WSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNEDWSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMGADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQF---EDDIKEEPLEASEDEHPIQ--SSANHPPMSESQAAGSSS 619
            L L +F +  GA   +G+L A +     ++FCI Y  +   L +  Q+    D + L D +N E C   P +  P   +KV LV     T NCS+  +  V++                 +      L  + ++++      S    +I +T     D+  + L+        + +++ P+     +D S+ +I+ +AVFTV +GS WSG  K +L LK   KLS            G       +P    QT  +    +M  RITP+ V +FV  M  MLLLLYFFF+YLVY II +FV+AS+++ Y+C EP +   S G      T R+P  N      ++E+ Q ++  F++A++  W + R E +SWILQDILGI FS+NMLK++RLPS KICTILL +LF YDIFFVFITP  T  G+SVMVEVA G  + E LPMVLRVP  N+DP+  C+  YS+LGFGDILVPGLLV+YCH +DLL   R ++Y+ T  + Y L LI TF  L+LM + QPALLY+VP TLIP  ++  +R E    W G ++   E D+   P+E  E    +    +  + P+   + +G+SS
Sbjct:   22 LILTYFKEVGGANYHYGVLAAESSS-ESKNFCIMYLEDFLPLPTVKQKE---DFRPLLDQSNREFCDTPPPEYHPSFEEKVVLVR----TSNCSVVSQAQVVQ-----------------NLGGAGLLVTVPEENMSAVEGNSSLAQDINITVALISDSSVRQLE--NLSADVRVLLFAPDSFN--VDFSLFIIWVVAVFTVAVGSCWSGLVKQSLHLKETTKLS------------GTEIEHHGKP----QTPRESEESSM--RITPILVAVFVLCMGAMLLLLYFFFDYLVYFIISLFVLASMVSVYSCLEPCMKRLSIG------TCRLPPVNFLCFKGSLEVYQVVVFLFAVALTVSWVIIRKESYSWILQDILGIAFSINMLKSVRLPSLKICTILLVLLFFYDIFFVFITPFLTVKGESVMVEVATGGSSQEVLPMVLRVPHFNFDPMSVCYKQYSLLGFGDILVPGLLVAYCHGYDLLVGNR-RVYFITTTVCYGLGLIITFFGLYLMRTPQPALLYLVPATLIPPILLGLVRKELSHIWNGYKYAGNEQDLATPPVEIVEPVPTVTNNENEENNPVFSREGSGASS 561          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|1238878917|ref|XP_022252688.1| (signal peptide peptidase-like 2B isoform X1 [Limulus polyphemus])

HSP 1 Score: 362.459 bits (929), Expect = 5.779e-114
Identity = 227/599 (37.90%), Postives = 327/599 (54.59%), Query Frame = 0

Query:   34 LPLVWFSQAMGAQSRFGLLVAVTEDMPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCS--PDDDLPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTTNIFVTALFHPDTKQKLLDIKRSHPHSKFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVM-WSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNEDWSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFT-----KNGKSVMVEVAMGADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQF---EDDIKEEPLEASEDEHPIQ--SSANHPPMSESQAAGSSS 619
            L L +F +  GA   +G+L A +     ++FCI Y  +   L +  Q+    D + L D +N E C   P +  P   +KV LV     T NCS+  +  V++                 +      L  + ++++      S    +I +T     D+  + L+        + +++ P+     +D S+ +I+ +AVFTV +GS WSG  K +L LK   KLS            G       +P    QT  +    +M  RITP+ V +FV  M  MLLLLYFFF+YLVY II +FV+AS+++ Y+C EP +   S G      T R+P  N      ++E+ Q ++  F++A++  W + R E +SWILQDILGI FS+NMLK++RLPS KICTILL +LF YDIFFVFITP  T     + G+SVMVEVA G  + E LPMVLRVP  N+DP+  C+  YS+LGFGDILVPGLLV+YCH +DLL   R ++Y+ T  + Y L LI TF  L+LM + QPALLY+VP TLIP  ++  +R E    W G ++   E D+   P+E  E    +    +  + P+   + +G+SS
Sbjct:   22 LILTYFKEVGGANYHYGVLAAESSS-ESKNFCIMYLEDFLPLPTVKQKE---DFRPLLDQSNREFCDTPPPEYHPSFEEKVVLVR----TSNCSVVSQAQVVQ-----------------NLGGAGLLVTVPEENMSAVEGNSSLAQDINITVALISDSSVRQLE--NLSADVRVLLFAPDSFN--VDFSLFIIWVVAVFTVAVGSCWSGLVKQSLHLKETTKLS------------GTEIEHHGKP----QTPRESEESSM--RITPILVAVFVLCMGAMLLLLYFFFDYLVYFIISLFVLASMVSVYSCLEPCMKRLSIG------TCRLPPVNFLCFKGSLEVYQVVVFLFAVALTVSWVIIRKESYSWILQDILGIAFSINMLKSVRLPSLKICTILLVLLFFYDIFFVFITPFLTVFFSLQKGESVMVEVATGGSSQEVLPMVLRVPHFNFDPMSVCYKQYSLLGFGDILVPGLLVAYCHGYDLLVGNR-RVYFITTTVCYGLGLIITFFGLYLMRTPQPALLYLVPATLIPPILLGLVRKELSHIWNGYKYAGNEQDLATPPVEIVEPVPTVTNNENEENNPVFSREGSGASS 566          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|880952392|ref|XP_012978506.1| (signal peptide peptidase-like 2B isoform X3 [Mesocricetus auratus])

HSP 1 Score: 351.288 bits (900), Expect = 1.269e-109
Identity = 225/577 (38.99%), Postives = 319/577 (55.29%), Query Frame = 0

Query:   49 FGLLVAVTED--MPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLP--DLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTT-NIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSS----ANHPPMSE 611
            FG+L  V++      + +CI Y P+  +L    Q+  +  L  L DL++ + CS   DLP  DL  +VALV+     GNC+  ++V + +      +L  S                  +  VP   N ++Y   +I V  L H D    L DI R   H+  + +Y P E    +D ++++IF MAV TV LG  W+G    +++ +Y +                +RD   E+            HE  +V +TP+ + +FV   C ML+LLY+F++ LVY+IIG+F +AS    Y+C  P V       P C T R+P  NL       + R  LL  F + ++ +W VFRNED W+W+LQDILGI F L ML+T+RLP+FK CT+LLS+LF+YD+FFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  +IY+    + Y L L+ TF++L LM+  QPALLY+VP TL+    VA  R E   FWTG  F  ++ +     +E   P + S    + HPP  E
Sbjct:   22 FGVLRVVSQSGGTRGKDYCILYNPQWAHLP---QDLSKVSLLKLRDLSSTQLCS-HLDLPVEDLANQVALVA----RGNCTFYEKVRLAQGSGARALLVVSK-----------------EKLVPPGGNKTQYEEISIPVALLSHRD----LQDIFRRFGHAVMVALYAPSEP--VMDYNMVIIFVMAVGTVALGGYWAG--SRDVKKRYMKH---------------KRDDGPEK------------HEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVR----KLPFC-TCRVPDNNLPYFHKRPQARMLLLALFCVTVTVVWGVFRNEDQWAWVLQDILGIAFCLYMLRTIRLPTFKACTLLLSVLFIYDVFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLMASCTVALWRRELGAFWTGSGFVKNVPQSSWAPAEGPAPPRDSDAPLSQHPPGEE 532          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|880952384|ref|XP_012978504.1| (signal peptide peptidase-like 2B isoform X1 [Mesocricetus auratus])

HSP 1 Score: 351.288 bits (900), Expect = 1.812e-109
Identity = 225/577 (38.99%), Postives = 319/577 (55.29%), Query Frame = 0

Query:   49 FGLLVAVTED--MPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLP--DLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTT-NIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSS----ANHPPMSE 611
            FG+L  V++      + +CI Y P+  +L    Q+  +  L  L DL++ + CS   DLP  DL  +VALV+     GNC+  ++V + +      +L  S                  +  VP   N ++Y   +I V  L H D    L DI R   H+  + +Y P E    +D ++++IF MAV TV LG  W+G    +++ +Y +                +RD   E+            HE  +V +TP+ + +FV   C ML+LLY+F++ LVY+IIG+F +AS    Y+C  P V       P C T R+P  NL       + R  LL  F + ++ +W VFRNED W+W+LQDILGI F L ML+T+RLP+FK CT+LLS+LF+YD+FFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  +IY+    + Y L L+ TF++L LM+  QPALLY+VP TL+    VA  R E   FWTG  F  ++ +     +E   P + S    + HPP  E
Sbjct:   36 FGVLRVVSQSGGTRGKDYCILYNPQWAHLP---QDLSKVSLLKLRDLSSTQLCS-HLDLPVEDLANQVALVA----RGNCTFYEKVRLAQGSGARALLVVSK-----------------EKLVPPGGNKTQYEEISIPVALLSHRD----LQDIFRRFGHAVMVALYAPSEP--VMDYNMVIIFVMAVGTVALGGYWAG--SRDVKKRYMKH---------------KRDDGPEK------------HEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVR----KLPFC-TCRVPDNNLPYFHKRPQARMLLLALFCVTVTVVWGVFRNEDQWAWVLQDILGIAFCLYMLRTIRLPTFKACTLLLSVLFIYDVFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLMASCTVALWRRELGAFWTGSGFVKNVPQSSWAPAEGPAPPRDSDAPLSQHPPGEE 546          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|880952395|ref|XP_012978507.1| (signal peptide peptidase-like 2B isoform X4 [Mesocricetus auratus])

HSP 1 Score: 350.132 bits (897), Expect = 3.872e-109
Identity = 225/577 (38.99%), Postives = 316/577 (54.77%), Query Frame = 0

Query:   49 FGLLVAVTED--MPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLP--DLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTT-NIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSS----ANHPPMSE 611
            FG+L  V++      + +CI Y P+  +L    Q+  +  L  L DL++ + CS   DLP  DL  +VALV+     GNC+  ++V + +      +L  S                  +  VP   N ++Y   +I V  L H D    L DI R   H+  + +Y P E    +D ++++IF MAV TV LG  W+G       +K+                  +RD   E+            HE  +V +TP+ + +FV   C ML+LLY+F++ LVY+IIG+F +AS    Y+C  P V       P C T R+P  NL       + R  LL  F + ++ +W VFRNED W+W+LQDILGI F L ML+T+RLP+FK CT+LLS+LF+YD+FFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  +IY+    + Y L L+ TF++L LM+  QPALLY+VP TL+    VA  R E   FWTG  F  ++ +     +E   P + S    + HPP  E
Sbjct:   22 FGVLRVVSQSGGTRGKDYCILYNPQWAHLP---QDLSKVSLLKLRDLSSTQLCS-HLDLPVEDLANQVALVA----RGNCTFYEKVRLAQGSGARALLVVSK-----------------EKLVPPGGNKTQYEEISIPVALLSHRD----LQDIFRRFGHAVMVALYAPSEP--VMDYNMVIIFVMAVGTVALGGYWAGSRDVKKYMKH------------------KRDDGPEK------------HEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVR----KLPFC-TCRVPDNNLPYFHKRPQARMLLLALFCVTVTVVWGVFRNEDQWAWVLQDILGIAFCLYMLRTIRLPTFKACTLLLSVLFIYDVFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLMASCTVALWRRELGAFWTGSGFVKNVPQSSWAPAEGPAPPRDSDAPLSQHPPGEE 531          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|880952388|ref|XP_012978505.1| (signal peptide peptidase-like 2B isoform X2 [Mesocricetus auratus])

HSP 1 Score: 350.132 bits (897), Expect = 5.765e-109
Identity = 225/577 (38.99%), Postives = 316/577 (54.77%), Query Frame = 0

Query:   49 FGLLVAVTED--MPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLP--DLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYTT-NIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSS----ANHPPMSE 611
            FG+L  V++      + +CI Y P+  +L    Q+  +  L  L DL++ + CS   DLP  DL  +VALV+     GNC+  ++V + +      +L  S                  +  VP   N ++Y   +I V  L H D    L DI R   H+  + +Y P E    +D ++++IF MAV TV LG  W+G       +K+                  +RD   E+            HE  +V +TP+ + +FV   C ML+LLY+F++ LVY+IIG+F +AS    Y+C  P V       P C T R+P  NL       + R  LL  F + ++ +W VFRNED W+W+LQDILGI F L ML+T+RLP+FK CT+LLS+LF+YD+FFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  +IY+    + Y L L+ TF++L LM+  QPALLY+VP TL+    VA  R E   FWTG  F  ++ +     +E   P + S    + HPP  E
Sbjct:   36 FGVLRVVSQSGGTRGKDYCILYNPQWAHLP---QDLSKVSLLKLRDLSSTQLCS-HLDLPVEDLANQVALVA----RGNCTFYEKVRLAQGSGARALLVVSK-----------------EKLVPPGGNKTQYEEISIPVALLSHRD----LQDIFRRFGHAVMVALYAPSEP--VMDYNMVIIFVMAVGTVALGGYWAGSRDVKKYMKH------------------KRDDGPEK------------HEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVR----KLPFC-TCRVPDNNLPYFHKRPQARMLLLALFCVTVTVVWGVFRNEDQWAWVLQDILGIAFCLYMLRTIRLPTFKACTLLLSVLFIYDVFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLMASCTVALWRRELGAFWTGSGFVKNVPQSSWAPAEGPAPPRDSDAPLSQHPPGEE 545          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|625198827|ref|XP_007641421.1| (PREDICTED: signal peptide peptidase-like 2B isoform X1 [Cricetulus griseus])

HSP 1 Score: 348.591 bits (893), Expect = 1.202e-108
Identity = 229/599 (38.23%), Postives = 324/599 (54.09%), Query Frame = 0

Query:   49 FGLLVAVTED--MPDQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLP--DLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDSVPIRFNASEYT-TNIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIK-------EEPLEASEDEHPIQSSANHPPMSE-------SQAAGSSSMARN 623
            FG+L  V++      + +CI Y P+   L  ++    +  L  L DL++ + CS + DLP  DL  ++ALV+     GNC+  ++V + +      +L  S                  +  VP   N ++Y   +I V  L H D    L DI +   H+  + +Y P+E    +D ++++IF MAV TV LG  W+G       +K+                  +RD   E+            HE  +V +TP+ + +FV   C ML+LLYFF++ LVY+IIG+F +AS    Y+C  P V       P C T R+P  NL       + R  LL  F + ++ +W VFRNED W+W+LQD+LGI F L MLKT+RLP+FK CT+LL +LF YD+FFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  +IY+    + Y L L+ TF++L LM+  QPALLY+VP TLI    VA  R E   FWTG  F  D+        E P+   + + PI   + HPP  E       ++ AG++  A N
Sbjct:   22 FGVLRVVSQSGGTRGKDYCILYNPQWARLPHDLS---KVSLLKLRDLSSTQLCS-NLDLPVEDLTNQIALVA----RGNCTFYEKVRLAQASGARALLIVSK-----------------EKLVPPGGNKTQYEEISIPVALLSHRD----LRDIYKRFGHAVMVALYAPKEP--VMDYNMVIIFLMAVGTVALGGYWAGSRAVKKIMKH------------------KRDDGPEK------------HEDEAVDVTPVMICVFVVMCCFMLVLLYFFYDRLVYVIIGIFCLASSTGLYSCLAPCVR----KLPFC-TCRVPDNNLPYFHKRPQARMLLLAFFCVTVTVVWGVFRNEDQWAWVLQDVLGIAFCLYMLKTIRLPTFKACTMLLLVLFFYDVFFVFITPFLTKSGNSIMVEVATGPSNSSTQEKLPMVLKVPRLNTSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RIYFMACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLISSCTVALWRQELGVFWTGSGFAKDVPQSSWTPMEGPVPRRDSDAPI---SQHPPGEEPAKRPLPTEEAGAADPAAN 550          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|513009014|ref|XP_004865933.1| (signal peptide peptidase-like 2B isoform X1 [Heterocephalus glaber])

HSP 1 Score: 348.977 bits (894), Expect = 1.267e-108
Identity = 226/600 (37.67%), Postives = 327/600 (54.50%), Query Frame = 0

Query:   48 RFGLLVAVTE-DMP-DQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLPDLG--QKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIA---DDSVPIRFNASEYTTNIFVTALFHPDTKQKLLDIKRSHPHS-KFIVYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSSAN---HPPMSESQAAG--SSSMARNKKAQEED 630
             +G++  V+E  +P  + +CI Y P+  +L  ++ +A    L  L D ++   CSP D LP  G   ++ LV+     GNC+  ++V +                     Q   A GL+    +  VP   N ++Y       AL    + + +LDI RS  H  +  +Y P E    LD ++++IF MAV TV LG  W+G    +++ +Y +                +RD       PE Q       E  +V +TP+ + +FV   C+ML+LLY+F+++LVY+IIG+F +AS    Y+C  P V       PCC   R+P  +L       + R  LL  F +AIS +W +FRNED W+W+LQD LGI F L MLKT+RLP+FK CT+LL +LF+YD+FFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  ++Y+  + + Y + L+ TF++L LM+  QPALLY+VP  L+    +A  R E   FWTG  F  D+ + P   ++   P + S       P  E QA G  S+       A EE+
Sbjct:   23 EYGMVHVVSEIAVPRGKDYCILYNPQWAHLPHDLGKA---SLLQLGDWSSSLLCSPSD-LPAGGFSNQIPLVA----RGNCTFYEKVRLA--------------------QGSGARGLLVVSKEKLVPPGGNKTQYEEIGIPVALL---SYKDMLDIFRSFGHKVRVALYAPSEP--VLDYNMVIIFIMAVGTVALGGYWAG--SRDVKKRYMKH---------------KRDDG-----PEKQ-------EDEAVDVTPVMICVFVVMCCSMLVLLYYFYDHLVYVIIGIFCLASSTGLYSCLAPCVR----RLPCC-GCRVPDNSLPYFHKRPQARMLLLALFCVAISVVWGIFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFIYDVFFVFITPFLTKSGNSIMVEVATGPSDSATHEKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDVQVQSS-RVYFVASTIAYGIGLLVTFVALALMQRGQPALLYLVPCMLVTSFAIALWRRELGAFWTGSGFAKDLPQSPWAPADSPQPPRDSDGPCPQQPPGEEQAKGPLSTEQPPEPSASEEE 554          

BLAST of signal peptide peptidase-like 2b isoform x1 vs. nr
Match: gi|1040099692|gb|OBS60329.1| (hypothetical protein A6R68_08576, partial [Neotoma lepida])

HSP 1 Score: 348.591 bits (893), Expect = 1.273e-108
Identity = 228/604 (37.75%), Postives = 329/604 (54.47%), Query Frame = 0

Query:   49 FGLLVAVTEDMP--DQHFCIRYFPELHNLTSNIQEAPRYDLKDLTDLTNEETCSPDDDLPDLGQKVALVSAQNTTGNCSIADRVNVIEVRPLVPILFESSVLPIFHFQTHHALGLIADDS-VPIRFNASEYT-TNIFVTALFHPDTKQKLLDIKRSHPHSKFI-VYGPEEAERTLDGSIILIFCMAVFTVGLGSLWSGYTKHNLRLKYERKLSIPTGGVNYQSSNGRRDSSGEQPMPESQTSNQDHHEAMSVRITPLWVVLFVGGMCTMLLLLYFFFNYLVYIIIGMFVVASVIATYACFEPVVMWSYGAFPCCPTIRIPRCNLFICVINMELRQFLLLAFSIAISTIWCVFRNED-WSWILQDILGILFSLNMLKTLRLPSFKICTILLSILFVYDIFFVFITPLFTKNGKSVMVEVAMG---ADTGEQLPMVLRVPRLNYDPLHACWIPYSILGFGDILVPGLLVSYCHAFDLLRETRCKIYWSTANLFYALSLIATFISLFLMESAQPALLYIVPFTLIPIAIVATIRGEFMEFWTGDQFEDDIKEEPLEASEDEHPIQSS----ANHPPMSE-------------SQAAGSSSMARNKKA 626
            FG+L  V++      + +C+ Y P+  +L  ++    +  L  L DL++ + CS  D   DL  ++ALV+     GNC+  ++V           L +SS           AL +++ +  VP   N ++Y   +I V  L H D    L DI R   H+  + +Y P E    +D ++++IF MAV TV LG  W+G       +K++R              +G          PE Q       E  +V +TP+ + +FV   C ML+LLY+F+++LVY+IIG+F +AS    Y+C  P V       P C T R+P  NL       + R  LL  F I ++ +W +FRNED W+W+LQDILGI F L MLKT+RLP+FK CT+LL +LF+YD+FFVFITP  TK+G S+MVEVA G   + T E+LPMVL+VPRLN  PL  C  P+S+LGFGDILVPGLLV+YCH FD+  ++  +IY+    + Y L L+ TF++L LM+  QPALLY+VP TL+    VA  R E   FWTG  F  D+ +     +E   P++ S    +  PP  E              + AG+++ AR++  
Sbjct:   13 FGMLRVVSQSGGPRGRDYCLLYNPQWAHLPRDLN---KVSLLKLRDLSSTQLCSYRDLPVDLTNQIALVA----RGNCTFYEKVR----------LAQSS--------GARALLIVSKEKLVPPGGNKTQYEEISIPVALLSHRD----LRDIFRRFGHAVMVALYAPSEP--VMDYNMVIIFVMAVGTVALGGYWAGSRDVKKYMKHKR-------------DDG----------PEKQ-------EDEAVDVTPVMICVFVVMCCFMLVLLYYFYDHLVYVIIGIFCLASSTGLYSCLAPCVR----KLPFC-TCRVPDNNLPYFHKRPQARMLLLALFCITVTIVWGIFRNEDQWAWVLQDILGIAFCLYMLKTIRLPTFKACTLLLVVLFIYDVFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSS-RIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLMTSCTVALWRRELGAFWTGSGFAKDVPQSSWAPAEGPAPLRDSDAPISQQPPSEELAKKPLPTEEAALPEEAGAANPARDRDG 549