Query:   88 IGDMVLTADQYSADFLGLEEFSGIRGDNY--RWPNGVIPYQIDGSISR---------------------------DSSLVLIKRGRGGCGSSSVGRQGGRQTLSISV---GCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNI----RRQNQHN----------------------FRKQVNG---LTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPNQ 254
            I  ++   + Y A     + F   RGD     WPNGVIPY I    ++                           D + V  + G  GC ++ +G    R T +I +   GC + R I HE +H  G+ HEQ+RPDRD++++I +NNI    R   Q                        F +  NG   LTF +PYD  S+MHY++ A+SKN   T+  K PT N+
Sbjct:    3 IIKLIFLFNLYGAS----QSFVSFRGDQVPQTWPNGVIPYHISSFFTKEEAQNIDNTLRQIESQSCIRFRPKQWYDWNSVFFQIGIKGCSTTGIGYHPFRGTTTIYLKRPGCMSLRAISHEILHVLGFMHEQNRPDRDNYIQINWNNIESNPRAYYQFARGKFPYEEMPECKTHLFYRLKPFVECYNGFETLTFGLPYDYKSVMHYTAFAYSKNGEPTMTPKFPTSNR 226          

Query:   61 VDDLVTSIEEDGIANEELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGS---------------ISRDSSLVLIKR-----------GRGGCGSSSVGRQGGRQTLSISV---GCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVN----------GL----------------TFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPT 251
            V  L++S+      ++E   DE    V+ D    A  YS +F+G        G + RWPNG++PY I  +               IS  + +  ++R           G  GC ++++G   GR    + +   GC +   I+HE +H  G+ HEQ+RPDRD +V I + NIR     NF + +           G+                TF + YD  SIMHY    FS N  NTI  K  T
Sbjct:    6 VITLLSSLFFSLCLSDENVSDEGSCRVLVDAHDRAAMYSRNFIG--------GRSNRWPNGIVPYTISSNFSSSQRQTIMDSIKHISDRTCVKFVQRTNQANYVDIFTGASGC-NANLGYNSGRARSVLHLQSDGCVHLGIIVHELLHILGFAHEQTRPDRDQYVTISWENIRSGTYSNFWRALGENEAVTIPYCGIVGIDQYDNCNAGFRTSTFGMAYDYGSIMHYGLTYFSTNGQNTITLKKST 242          

Query:  104 GLEEFSGIRGDNYRWPNGVIPYQIDGSI-SRDSSLVL-------------------------IKRGRGGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRK-QVNGLT-FNVPYDGLS 228
            G  E + IR  + +WP G +PY I  +  SR+ +++                          I +G G   SSSVGR GG QT+S+  G      +IHE +HA G++HEQSR DRDS V+I++NNI    + NF K  +N +     PYD  S
Sbjct:   42 GALERNAIRNTHKKWPGGKVPYVISSAYDSRERAIIASAFEDYAEKTCVRFLPRTNQHAYVHIMKGDGC--SSSVGRTGGIQTISLGNGXIYKGIVIHELMHAIGFWHEQSRHDRDSHVKILWNNIIDSMKFNFLKYDLNKIDHLGAPYDTCS 192          

Query:   87 VIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGSIS---RDSSLVLIKRGRGGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQV--------------------------NGLTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPNQ 254
            V+ D    A  YS +F+G        G + RWPNG++PY I    S   R + +  IK         S+   G     S  +G      I HE +H  G+ HEQ+RPDRD +V++ + NI+     NF + +                             TF + YD  SIMHY  R FS N  NTI  K  T  Q
Sbjct:   32 VLVDTYDRAAMYSRNFIG--------GRSNRWPNGIVPYAISSDFSSSQRQTIMDAIKH--------SLHWWGWMLRKSWILG-----VITHELLHILGFAHEQTRPDRDQYVKVNWENIKSGTHSNFWRALGENEPATIPYCGRVGVDQYDNCYAGFRASTFGLNYDYGSIMHYGLRYFSTNGQNTITLKKSTTAQ 207          

Query:   87 VIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGS---------------ISRDSSLVLIKR-----------GRGGCGSSSVG---RQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQV--------------------------NGLTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPNQ 254
            V+ D    A  YS +F+G        G + RWPNG++PY I                  IS  + +  ++R           G  GC  +++G   R+G  Q    S GC     I HE +H  G+ HEQ+RPDRD +V+I + N++     NF + +                             TF + YD  SIMHY  R FS N  NT+  K  T  Q
Sbjct:   32 VLVDAYDRAAMYSRNFIG--------GRSNRWPNGIVPYTISSDFSSSQRQTIMDAFKHISDRTCVTYVERTNEANYLDIFTGGDGC-FANIGYNSRRGRSQLHLQSNGCVVLGIITHELLHILGFSHEQTRPDRDQYVKINWENLKIGTHSNFWRALGENEPAAIPYCGSVGVDQYDNCYAGFRASTFGLNYDYGSIMHYGLRYFSTNGRNTMTLKKSTTAQ 245          

Query:   61 VDDLVTSIEEDGIANEELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGS---------------ISRDSSLVLIKR-----------GRGGCGSSSVGRQGGRQTLSISV---GCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVN-------------GL-------------TFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPT----PNQT 255
            V  L++S+      ++E   DE    V+ D    A  YS +F+G        G +  WPNG++PY I  S               IS  + +  ++R           G  GC  +++G    R    + +   GC +   I HE +H  G+ HEQ+RPDRD +V I + NIR     NF + +              G+             TF + YD  SIMHY    FS N  NTI  K  T    PN++
Sbjct:    6 VITLLSSLFFSLCLSDENVSDEGSCRVLVDAHDRAAMYSRNFIG--------GKSNXWPNGIVPYTISSSFSSXQRQTIMDSIKHISDRTCVKFVERTNEANYVDIFTGGDGC-YANLGYNSRRSRSVLHLQRNGCVHLGVIAHELLHILGFAHEQTRPDRDQYVTISWENIRSGTYSNFWRALGENEAATIPYCGNVGIDQYDNCYAGFRTSTFGMAYDYGSIMHYGLTYFSTNGQNTITLKKSTTARIPNRS 250          

Query:   61 VDDLVTSIEEDGIANE-ELEPDENGNYVIGDMVLTADQYSADFLGLEEFSG---------IRGDNYR----WPNGVIPYQIDGSIS----------------------------RDSSLVLIKRGRGGCGSSSVGRQG-GRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRK----QVNGLTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIP----TPNQTTIHQPAQTIGRDNGE-AQPM 274
             +DL+     + I+N+ +++P ++  +V GD+ +  ++YS+     + +SG          R    R    W   VIPY++D + S                              + +V  +R  G C  S VG++G G Q +SI   C     ++HE  H  G++HE +RPDRD +V I+  NI    ++NF +    +VN L     YD  SIMHY+   FSK  G  +++  P      N+    +  Q I   NG+ AQ M
Sbjct:   25 TEDLLNLQFRNLISNDVDMDPCKSKKFV-GDIAIPTEEYSS----AQTWSGSISNKLIKSKRAATARPERIWEYAVIPYEVDANFSGVHKGLFKQAMRHWENFTCVQFVERTDEHPNWIVFTERPCGCC--SFVGKRGNGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDDWVTIMRENIMVGQEYNFNRLTSEEVNSLGLRYDYD--SIMHYARNTFSK--GTYLDTIFPRDDLPENRDDFPEIGQRIKLSNGDIAQTM 279          

Query:   95 ADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGS---------------ISRDSSLVLIKR-----------GRGGCGSSSVGRQGGRQTLSI---SVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQV--------------------------NGLTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPNQ 254
            A  YS +F+G        G + RWPNG++PY I  +               IS  + +  ++R           G  GC  ++ G    R    +   S GC     I HE +H  G+ HEQ+RPDRD +V+I + NI      NF + +                             TF + YD  SIMHY  R FS+N  +TI  K  T  Q
Sbjct:   53 AAMYSRNFIG--------GRSNRWPNGIVPYIISSNFTSSQRQTIMDAIKHISDRTCVNFVERTNQTNYVDIFTGESGC-YANFGYNSWRSISKLHLQSNGCVILGIITHELLHILGFSHEQTRPDRDQYVKINWENIDTAAYPNFWRALGENEPATIGYCGNVGIDQYDNCIAGFRAATFGLDYDYGSIMHYGLRFFSRNNKDTISLKKSTTAQ 258          

Query:  144 RGGCGSSSVGRQGGRQTLSI------SVGCF-NDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVN 216
            + GC S  VG+QGGRQ LS+      S  C  N   I+HE +HA G+YHE SRPDRD F+ IV +N+++    NF K+  
Sbjct:  107 KPGCWSF-VGKQGGRQDLSLRRPTKKSCYCLCNSGRILHEVLHALGFYHEHSRPDRDKFIEIVSSNVQKGKLQNFSKKTK 185          

Query:   75 NEELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGS---------------ISRDSSLVLIKR-----------GRGGCGSSSVG---RQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQV--------------------------NGLTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPNQT 255
            +EE    E+   ++ D    A  YS +F+G        G + RWPNG++PY I                  IS  + +  +++           G  GC  +++G   R+   Q    S GC     IIHE +H  G+ HEQ+R DRD +V I + NI+     NF + +                             TF + YD  SIMHY  + FS N  NTI  K  T  Q 
Sbjct:   20 SEENVSGESSCRMLVDAYDRAVIYSRNFVG--------GRSNRWPNGIVPYTISSDFSSSQQQTIMDAINHISDRTCITFVEKTNEANYVDIFTGGKGC-YANLGYNSRRARSQVHLQSNGCVVLGVIIHELLHILGFSHEQTRSDRDQYVEIKWENIQSGTHSNFWRALGENEPATIPYCGNVGIDQYDNCYAGFRASTFGLDYDYGSIMHYGLKYFSTNGQNTITLKKSTTAQV 246          

Query:  103 LGLEEFSG-----------IRGDNYRWPNGVIPYQIDGSISRDSSLVLI---KRGR----------------------GGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESKI 249
            LGL+ F G           I GDNYRWP+  IPY ++ S+  ++  V++   +R R                       GC SS      G+Q LSI   C    T+ HEF+HA G++HEQSR DRD ++ IV++ I    +HNF    + +  + NVPYD  S+MHYS  AF     +TI +KI
Sbjct:   46 LGLDLFEGDIKLEASGRNSIIGDNYRWPH-TIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWSGEENYISVFKGSGCWSSVGNIHAGKQELSIGTNCDRIATVQHEFLHALGFWHEQSRADRDDYITIVWDRILSGKEHNFNIYNDSVSDSLNVPYDYTSVMHYSKTAFQNGTESTIITKI 229          

Query:  103 LGLEEFSG------------IRGDNYRWPNGVIPYQIDGSISRDSSLVLI---KRGR----------------------GGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESKI 249
            LGL+ F G            I G+ YRWP+  IPY ++ S+  ++  V++   +R R                       GC SS   R+ G+Q LSI   C    T+ HEF+HA G++HEQSR DRD +VRI+++ I    +HNF    + +  + NVPYD  S+MHYS  AF      TI ++I
Sbjct:   44 LGLDLFEGDIRLDRAQIRNSIIGEKYRWPH-TIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRIATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKTAFQNGTEPTIVTRI 228          

Query:  103 LGLEEFSG-----------IRGDNYRWPNGVIPYQIDGSISRDSSLVLI---KRGR----------------------GGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESKI 249
            LGL+ F G           I GD+ RWP+  IPY ++ S+  ++  V++   +R R                       GC SS      G+Q LSI   C    T+ HEF+HA G++HEQSR DRD +V IV++ I+   +HNF    + +  + NVPYD  S+MHYS  AF     +TI ++I
Sbjct:   46 LGLDLFEGDIKLEANGKNSIIGDHKRWPH-TIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWSGEANYISVFKGSGCWSSVGNIHAGKQELSIGTNCDRIATVQHEFLHALGFWHEQSRADRDDYVIIVWDRIQPGKEHNFNIYNDSVSDSLNVPYDYTSVMHYSKTAFQNGTESTIVTRI 229          

Query:  118 WPNGVIPYQIDGSISRDS---------------------------SLVLIKRGRGGCGSSSVGRQGGRQTLSISV-GCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPNQTTIHQ 259
            WP G +PY ++  ++ D                              + +KR      SS VGR GG QT+S+ V  CF+   I HE +HA G++HE SR DRD FV I  +NIR     NF K    +  +  +PYD  S+MHY   AFS+N   TI   IP  N+  + Q
Sbjct:  125 WPEGQVPYMLEEGMTNDQRTAIAQAFDEYKTKTCVRFVPKTDDDFDYIYVKRNVAFGCSSYVGRAGGNQTVSLEVDKCFSKGIIAHELMHALGFFHEHSRTDRDDFVDINEDNIRPGMMRNFEKYPRKIIDSLGMPYDYESVMHYHKLAFSRNGKPTI---IPKDNEADVGQ 293          

Query:  108 FSGIRGDNYRWPNGVIPYQIDGSIS--------------RDSSLVLIKRGRG-----------GCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGLTFNVP---YDGLSIMHYSSRAFSKNRGNTIES 247
            F+ ++     W  GVIPY++D + S              R ++ +  ++  G           GC  S VGR GG+Q +S+  GCF    I+HE +H+ G++HE SR DRD  ++I ++NI    +  F K ++ +  ++    YD  SIMHY S AFS+N  NTIE+
Sbjct:   71 FNALKNKQLTWEGGVIPYEMDTAFSPNEIKILEKAFDSYRRTTCIRFEKREGQTDYLNIVKGYGC-YSQVGRTGGKQEISLGRGCFFHEIIVHELMHSVGFWHEHSRADRDDHIKINWDNILPGMKSQFDK-ISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIET 236          

Query:  117 RWPNGVIPYQIDGSISRDSSLVLIKRGR--------------------------GGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRK--QVNGLTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIP 250
            RWPNG IPY I    +     VL +  +                           GC  S VGR GGRQ LS+  GC    T IHE +H+ G+YHE  R DRD ++ I++NNI +     F +        +   YD  S+MHY S AFSKN   T+ +K P
Sbjct:  109 RWPNGRIPYVISSQYNERERAVLARAFQEYHSRTCIRFVPRTSFDQDYLYIGKIDGC-YSDVGRAGGRQELSLDDGCLQYNTAIHELMHSVGFYHEHERWDRDQYITILWNNIDKDAYDQFGRVDLTESSYYGQAYDYYSVMHYDSLAFSKNGFETLVAKRP 269          

Query:  108 FSGIRGDNYRWPNGVIPYQIDGSI---------------------------SRDSSLVLIKRGRGGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPNQTTIHQ 259
            ++ I+     WP G IPY I                               + D + V I   RG    S VG+ GG+Q+LS+  GC     I+HE +HA G++HEQSR DRD  + I++NNI+   Q  F K  +G   +    YD  SIMHY ++AFS+N   T+   IP  N  TI Q
Sbjct:  113 YNAIKNRLQLWPEGRIPYTISSQYSSYSRSLIAASMQEYASHTCIRWVPKEAADVNYVHIYPDRGC--YSMVGKMGGKQSLSLGSGCIQKGIILHELMHAVGFFHEQSRTDRDDHITIMWNNIQAGMQGQFEKYGHGTIQSLGTGYDYGSIMHYGTKAFSRNGQPTM---IPKKNGATIGQ 288          

Query:   89 GDMVLTADQYSA-------DFLGLEEFSGIRGDNYRWPNGVIPYQIDGSISRDSSLV------------------------------LIKRGRGGCGSSSVGRQ-GGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNG--LTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPN 253
            GDM+LT DQ          +  G ++      ++ RWP  VIPY I  S S  SSL+                               +   RG    S VG+   G Q +SI  GC    TI+HE  HA G++HEQSRPDRD ++ +++ NI+   QHNF K   G   + NV YD  SIMHY    FS N   TI ++ P  N
Sbjct:   66 GDMMLTEDQQRESKEAIDDEMTGRKKRKATIYESQRWPYKVIPYVISPSSSGQSSLIRNAMDHWEQNTCLRFEPRTSSHSRQLGHNAYLSFFRGSGCWSYVGKAFNGEQQISIGNGCAYFGTIVHEIGHAIGFHHEQSRPDRDDYINVLYQNIQSGRQHNFAKYTWGRVTSRNVEYDVGSIMHYGGYGFSSNGRPTITTRDPRLN 270          

Query:   84 GNYVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQID---GSISRD------------SSLVLIKRGRG------------GCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRK-QVNGLT-FNVPYDGLSIMHYSSRAFSKNRGNTIESK 248
            GNY  GD++L + +   +       + I+    RWPN  IPY +    GS +R             + +  + R               GC  S VG+ GG+Q +S+  GC    TI+HE +HA G++HEQSR DRDS++ +V+ N+       F K  +N ++  + PYD  SIMHY   AFS +   T+  K
Sbjct:   70 GNYSEGDILLESPKKFVEENNKLGRNAIKQIYRRWPNNEIPYTLSSQYGSYARSVIANAMNEYHTKTCVKFVARDPSKHHDYLWIHPDEGC-YSLVGKTGGKQPVSLDSGCIQVGTIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYNLNVISHLDEPYDYASIMHYGPYAFSGSGKKTLVPK 262          

Query:   67 SIEEDGIANEELEPDENGNY-VIGDMVLTADQY-----SADF-LGLEEFSGIRGDNY-RWPNGVIPYQIDGSISRDSSLVLIKRGR-------------------------GGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRK-QVNGLTFNVPYDGLSIMHYSSRAFSK 239
            ++++    N+EL  + N  + V GDM+LT  Q      S D  L +   S I+G +  RW N ++PY I    S     +L+   R                          GC  S VG+ GGRQTLS++  C  D  I HE +HA G+ HE  RPDRDSF+R+ + N+      NF K + + + +   YD  SIMHY   AF +
Sbjct:   25 AVKQSWEINQELITEANKEHTVFGDMLLTPAQLIRYENSKDSDLSIRGVS-IKGSSMNRWSNNIVPYVISPQYSPAQKQILVSSLRYFERVSCFKFVERTTQNDYLFIVPLDGC-YSYVGKIGGRQTLSLAADCIADYIIWHEMMHAIGFEHEHQRPDRDSFIRVDYANVIPGQMINFDKLKTSHVEYPDIYDFKSIMHYDGYAFGR 229          

Query:   61 VDDLVTSIEEDGIANEELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGSISR---------------------------DSSLVLIKRGRGGCGSSSVGRQGGRQTLSIS--VGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGLTFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPN 253
            V++ ++ ++E         P+E G ++ GD+V     +S +        G+    YRWP GVIPY+I GS ++                           ++  +LI   + GC S  VGRQGGRQ L++   +   N  T IHE +H  G++HEQ+R +RDSFV I++ NIR   Q+NFR++     FNVPYD  SIMHYSS AFS N   TI +K P  N
Sbjct:   45 VNNAISHLQETENLKSSTNPEEIGVHIEGDIVQNTKLFSKN--------GVVSKTYRWPYGVIPYEIAGSFNQHDLEIIHYAILNFHLKTCVRFIPRRYNETDYILINNEKSGCWSY-VGRQGGRQRLNLESPICLINPGTAIHELMHVLGFFHEQNRQERDSFVEILYENIREGLQNNFRRRSRTAAFNVPYDYASIMHYSSTAFSHNGQPTIVAKQPEYN 257          

Query:   76 EELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGI-RG--DNYRWPNGVIPYQIDGSISRDS-----------------SLVLIKRG--------RGGCGSSS-VGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESK 248
            EE E D +     GDM+LT +Q  A   G +  + + RG   N RWP GV  YQIDG+++R S                  +   KR         R G G SS VGR GGRQT++++ GC+    + HE  HA G+YHEQSRPDRD++V I++NNI  +++ NF K   G   +   PYD  S+MHY SRAFSKN   TI +K
Sbjct:   19 EEAETDPD--VFEGDMILTPEQKMAAVNGWDVDAPLGRGGIKNKRWPGGVFVYQIDGALARSSKAMNAINGAFREWSSKTCITFKKRTNERDYAYFRIGSGCSSWVGRSGGRQTINLASGCWYVGIVAHEIGHALGFYHEQSRPDRDNYVTIMWNNIIEKSKFNFNKYNRGTIDSLGTPYDYGSVMHYGSRAFSKNGRPTIVAK 220          

Query:   78 LEPDENGN---YVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGSISRDSS--------------LVLIK-------------RGRGGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL---TFNVPYDGLSIMHYSSRAFSKNRGNTIESK 248
            + P+EN N      GDM LT +Q  A   GL+  + IR     WP GV+ Y IDG+++  S               L  I+             R  GGC +S VG++GG+Q + ++ GC+    ++HE  HA G+YHEQSRPDRD FV I+F NI  + QHNFRK +NG    TFN PYD  S+MHY    FSKN   TI +K
Sbjct:   16 MSPEENRNNRELFEGDMRLTPEQRRA-VSGLKR-AAIRNTRKLWPKGVMYYVIDGTLAGQSRARSAINQAINEYKRLTCIRLQRRTNQRDYVSFRSGGGC-ASWVGKRGGKQDIWLAPGCWTKGIVVHEIGHALGFYHEQSRPDRDKFVTILFQNIIPRFQHNFRK-MNGKAINTFNFPYDYGSVMHYGPTFFSKNGKPTIVAK 215          

Query:   64 LVTSIEEDGIANEELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGI-RG--DNYRWPNGVIPYQIDGSISRDS----------------------------SLVLIKRGRGGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESKIPTPNQTTIHQ 259
            L  ++     A    E + + +   GDM+LT +Q  A   G +  + + RG   N RWP GV  YQID  ++R S                            +    K+G  GC SS VGR G RQ ++++ GC+   T++HE  HA G+YHEQSRPDRD++V I+++NI  +N+HNF K   G   +   PYD  SIMHY SR FSKN   TI   +P  +  TI Q
Sbjct:    5 LACALIAVAFAASPEESETDPDVFEGDMILTPEQKMAAVNGWDVDAPLGRGGIKNRRWPGGVFVYQIDPVLARSSKAMNAINGAFREWSSKTCITFKKRTNERAYAYFKKG-SGC-SSYVGRTGSRQDVNLASGCWRVGTVVHEIGHALGFYHEQSRPDRDNYVTIMWDNIVERNKHNFNKYNRGTIDSLGTPYDYGSIMHYGSRYFSKNGKPTI---VPKRSGVTIGQ 228          

Query:   40 TLDV--LGGDEEGDYEDYSGLDPVDDLVTSIEEDGIANEELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGSISRD--------------------------SSLVLIKRGRGGCGSSSVGRQGGRQTLSI-SVGCFNDR-TIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGLT--FNVPYDGLSIMHYSSRAFSKNRGNTIESKI 249
            T+D+  LG +  G  ++ SG     D ++   E  + N    P+E G+Y  GD+++   Q           +GIR +  RWP G IPY I+G  + +                             + I+    GC SS VGR GGRQ +++ S GC + + T++HE +HA G+ HEQSRP+RD FVR+ +NNI+   + NF+K     T  FNVPYD  S+MHYS  AFSKN+  TIE K+
Sbjct:   45 TIDISSLGPEAYGLPKNESG-----DALSQWSESSLMN----PEEVGDYAEGDILMPPQQGR---------NGIREEVLRWPQGHIPYVIEGYFNSEQRETIMRAIADYHRLTCLRFVPYNGQKDYITIQSKNTGCWSS-VGRIGGRQEVNLQSPGCVSKKGTVLHELLHAIGFMHEQSRPERDDFVRVRYNNIKPGAESNFKKSTVKQTNDFNVPYDYNSVMHYSEFAFSKNQQKTIEPKV 267          

Query:   40 TLDV--LGGDEEGDYEDYSGLDPVDDLVTSIEEDGIANEELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGSISRD--------------------------SSLVLIKRGRGGCGSSSVGRQGGRQTLSI-SVGCFNDR-TIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGLT--FNVPYDGLSIMHYSSRAFSKNRGNTIESKI 249
            T+D+  LG +  G  ++ SG     D ++   E  + N    P+E G+Y  GD+++   Q           +GIR +  RWP G IPY I+G  + +                             + I+    GC SS VGR GGRQ +++ S GC + + T++HE +HA G+ HEQSRP+RD FVR+ +NNI+   + NF+K     T  FNVPYD  S+MHYS  AFSKN+  TIE K+
Sbjct:   45 TIDISSLGPEAYGLPKNESG-----DALSQWSESSLMN----PEEVGDYAEGDILMPPQQGR---------NGIREEVLRWPQGHIPYVIEGYFNSEQRETIMRAIADYHRLTCLRFVPYNGQKDYITIQSKNTGCWSS-VGRIGGRQEVNLQSPGCVSKKGTVLHELLHAIGFMHEQSRPERDDFVRVRYNNIKPGAESNFKKSTVKQTNDFNVPYDYNSVMHYSEFAFSKNQQKTIEPKV 267          

Query:   80 PDENG-----NYVIGDMVLTADQYSADFLGLEEFSGI-RGD--NYRWPNGVIPYQIDGSISRDS-SLVLIKRGR--------------------------GGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESK 248
            PDEN      +   GDM+LT +Q  A  +GL+  + + RG   N +WP GV+ Y ID S+SRDS ++  I++G                            GC SS VGR G RQ ++++ GC++   + HE  HA G+YHEQSRPDRDS+V I++NNI  +N+ NF K   G   +    YD  S+MHY SRAFSKN   TI +K
Sbjct:   18 PDENEGLDDPDLYEGDMILTDEQRMAAEMGLDVDNPLGRGSTKNRQWPGGVMAYVIDSSLSRDSRAMSAIRQGMEEWTSKTCIKFKQRTNERAYANFKLGSGC-SSYVGRTGSRQDINLARGCWHRGIVAHEIGHALGFYHEQSRPDRDSYVTIMWNNIIERNKFNFNKYDRGTIDSLGTKYDYGSVMHYGSRAFSKNGQPTIVAK 222          

Query:   78 LEPDENGNYVIGDMVLTADQYSADFLGLEEFSGIRGDNYRWPNGVIPYQIDGSISRD--------------------------SSLVLIKRGRGGCGSSSVGRQGGRQTLSI-SVGCFNDR-TIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGLT--FNVPYDGLSIMHYSSRAFSKNRGNTIESKI 249
            + P+E G+Y  GD+++   Q           +GIR +  RWP G IPY I+G  + +                             + I+    GC SS VGR GGRQ +++ S GC + + T++HE +HA G+ HEQSRP+RD FVR+ +NNI+   + NF+K     T  FNVPYD  S+MHYS  AFSKN+  TIE K+
Sbjct:   76 MNPEEVGDYAEGDILMPPQQGR---------NGIREEVLRWPQGHIPYVIEGYFNSEQRETIMRAIADYHRLTCLRFVPYNGQKDYITIQSKNTGCWSS-VGRIGGRQEVNLQSPGCVSKKGTVLHELLHAIGFMHEQSRPERDDFVRVRYNNIKPGAESNFKKSTVKQTNDFNVPYDYNSVMHYSEFAFSKNQQKTIEPKV 267          

Query:   76 EELEPDENGNYVIGDMVLTADQYSADFLGLEEFSGI-RG--DNYRWPNGVIPYQIDGSISRDS-----------------SLVLIKRG--------RGGCGSSS-VGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESK 248
            + LE + + +   GDM+LT +Q  A   G +  + + RG   N RWP GV  YQIDG+++R S                  +   KR         R G G SS VGR GGRQT++++ GC+    + HE  HA G+YHEQSRPDRD++V I++NNI  +++ NF K   G   +   PYD  S+MHY SRAFSKN   TI +K
Sbjct: 1180 KSLEAETDPDVFEGDMILTPEQKMAAVNGWDVDAPLGRGGIKNKRWPGGVFVYQIDGALARSSKAMNAINGAFREWSSKTCITFKKRTNERDYAYFRIGSGCSSWVGRSGGRQTINLASGCWYVGIVAHEIGHALGFYHEQSRPDRDNYVTIMWNNIIEKSKFNFNKYNRGTIDSLGTPYDYGSVMHYGSRAFSKNGRPTIVAK 1383          

Query:   80 PDENGNYVIGDMVLTADQYSADFLGLEEFSGI-RG--DNYRWPNGVIPYQIDGSISRDS-SLVLIKRGR--------------------------GGCGSSSVGRQGGRQTLSISVGCFNDRTIIHEFIHAFGYYHEQSRPDRDSFVRIVFNNIRRQNQHNFRKQVNGL--TFNVPYDGLSIMHYSSRAFSKNRGNTIESK 248
            P+EN     GDM+LTADQ  A   GL+  + + RG     +WP GV+ Y ID S+SRD  ++  I+ G                            GC SS VGR G RQ ++++ GC++   + HE  HA G+YHEQSRPDRD++V I+++NI  +N+ NF K   G   +   PYD  S+MHY  RAFSKN   TI +K
Sbjct:   18 PEENDYLYEGDMILTADQRMAANRGLDVDNPLGRGATKGRQWPGGVMAYVIDSSLSRDRRAMAAIREGMEEWTSKTCIRFKKRTNERAYANFKLGSGC-SSYVGRTGSRQDINLASGCWHRGIVAHEIGHALGFYHEQSRPDRDNYVTIMWDNIIERNKFNFNKYNRGTIDSLGTPYDYGSVMHYGGRAFSKNGRPTIVAK 217