Query:  282 LIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSD---PDEIVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQE---LDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGG--KGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPSV----FLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLM 809
            L+  T++G I+GV L      +V AW G+P+AQ PVG+LRF  P   +  + + +  T R P SC+Q +DT   G+ GA++WN   E SEDCLYL+++ PK       V VWI+GGG  +G+++L+ YD   +VS   ++FVA+QYR+  LGF+F  +  ++PGN G  DQ+ ALQW++NNI  FGG+P+ +T+ GE +G  S A+H++SP S  LF + I+QS++   PW     +E+  R R L++++ CP D      ++ CLR+KDA ++V +E+ G  S I  +PF P +DG F+ ESP K+LT+     K  +L+G+N  EG Y +MY+  D F + E   +D  D   S  + N  V+ +        RE I  EY D +      K R +A+DRM GD+ F+C    FA+  +  GN VY Y+F  RSS  PWP ++G  HGDEI F+FG  L   + Y   E+ L++ M+ YW NF K GNP+ S         WP +       L L   Y+  R  +G   ++C FW + L  L+
Sbjct:   36 LVITTKKGKIRGVTLKSATNREVDAWYGIPYAQPPVGNLRFRHPRHID--AWEGIKETTRPPNSCIQVVDTLFPGFEGAEMWNVNTEPSEDCLYLSVHVPKPRPTGSAVLVWIYGGGFYSGTSTLEVYDPRVLVSEENIIFVAMQYRVASLGFLFF-DTEDVPGNAGLYDQMMALQWVKNNIEEFGGDPDKITIFGEXAGGCSVALHLLSPLSRNLFSQAIMQSASALVPWGVITKKESIIRGRRLAEMMSCPYDEKNTKAMIECLRQKDATEMVNQEWIGIISGIAEFPFVPIVDGSFLDESPGKSLTTKNYK-KTNILIGANKEEGNYFIMYYLTDLFKNTESVYVDRTDFIRSVSELNHYVKKM-------GREAITFEYTDWLNPNDPIKNR-EAIDRMVGDYQFICPTADFARIYASTGNNVYMYYFTERSSTSPWPTWSGVLHGDEIAFVFGEALNKSKNYDKSEIALSKRMMGYWANFAKTGNPSLSADGTWSTNYWPLHTPTKQEVLELNANYS--RVLEGLRVKKCAFWKKYLPKLL 567          

Query:  281 ELIKKTQEGSIKGVNL----SPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDT--TGYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCP-------------------------------SDPDEIVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQE---LDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGG--KGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNP----SVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLM 809
            +L+  T++G I+GV L    + +V AW G+P+AQ PVG+LRF  P D   ++ D +  T + P SC+Q +DT   G+ G+++WNT  E SEDCLYL+++APK       V VWI+GGG  +G+++L+ YD   +VS   ++FV IQYR+  LGF+F  +  ++PGN G  DQ+ ALQW++NNI  FGG+P+ +T+ GE +G  S A+H++SP S  LF   I+QSS+   PW     +E+  R R L++ + CP                               ++ + ++ CL +KDA +LV +E  G    I+ +PF P +DG F+ ++PEK+L       K  +L+G N +EG + +MY+ P+ F   E   ++  D   S  D N  V           RE I  EY D +      K R +A+DRM GD+ F C    FA+  +  GN +Y Y+F  RSS  PWP ++G  HGDEI F+FG PL T + Y   E+ L++ +++YW NF K GNPN     +   + WP +       L L   Y+  R  +G   ++C FW   L  L+
Sbjct:   35 DLVITTRKGKIRGVTLKSATNKEVDAWYGIPYAQPPVGNLRFRHPKDI--NAWDGMKETTKHPNSCIQVVDTFFPGFEGSEMWNTNTEQSEDCLYLSVHAPKPRPTKSAVLVWIYGGGFYSGTSTLELYDPRVLVSEENIIFVGIQYRVASLGFLFF-DTEDVPGNAGLYDQMMALQWVKNNIEAFGGDPDKITIFGEXAGGCSVALHLLSPLSRXLFSXAIMQSSSALVPWGVISKKESIRRGRRLAEEMRCPYALVPWGVISKKESIRRGRRLAEEMRCPYGENNTNAMIECLLQKDATELVNQEGSGTVFGISEFPFVPIVDGKFMDKTPEKSLKEK-DYKKTNILMGVNKDEGNFFIMYYLPELFKKNENVYINRTDFIRSVSDLNIYVNNA-------GREAITFEYTDWLNPNDPIKNR-EAIDRMVGDYQFTCPTADFARIYASTGNNIYMYYFTERSSTSPWPTWSGVLHGDEIAFVFGEPLNTSKNYDDSEIALSKRIMSYWANFAKTGNPNVLANGNYSNKIWPLHTPIKQEVLELNANYS--RVFEGLRVRKCAFWKTYLPKLL 595          

Query:  281 ELIKKTQEGSIKGVNLSPQVRAWL----GVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTTGYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVI-LQSSALNAPWAYAEPEEARERARNLSQLLDCPS-DPDEIVGCLREKDAKDLVAKEFDGAPSAINSYP--FGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEG-FYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDL-IRSGGKGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSK------HGDEIEFMF 724
            ++I KT +G I G+        +     G+ +A  PV DLRF  P + EP +E   +        C Q          D+ N+     EDCL+LN+Y PK  +K   V V IHGG    G      + G   +   ++V V   YRLG LGF+   + T    N G  DQ+ AL+W++ NI  FGG+P  VT++GE +GA SA +  +SP ++GLF  VI L  +AL   +    P+EA   A+ L+  L+C S D  +I+ C+  K  +D+V K    +     ++P  F P +DGD + + PE  L++G   SK+P++LG   N G FY  +    ++F +   D++  D        V+     +     R + K  + ++ + +  + R + ++ +  D  F    + FA+ ++ +    Y Y FD+R  Q     + G +      HGDE++++F
Sbjct:   20 DMIVKTSKGPIMGLREDSSSNGYFYSFKGIRYAMPPVEDLRFKAPTELEPWTE--TVEAVEDGHICPQ---------YDIANSIPLGDEDCLFLNVYTPKIDSKKRAVMVHIHGGAFILGGGVSHLF-GPDYLMENDIVLVNFNYRLGALGFL-TTKDTMETANNGIKDQIMALKWVKENIDKFGGDPNKVTIIGEDAGAASATILSMSPAAQGLFQGVIALSGNALCDQFIQNNPDEA---AKELAARLECSSTDGKDIIECISRKTQQDIVEKS--NSMMMFYTFPRWFAPNVDGDILPDRPENLLSNGQF-SKVPIVLGQTKNGGAFYYRLTI--NSFNNGGYDDNFIDHKLPRLLPVMTNYNSKLYPITRSIRKRYFVNVDMENEDEFRPRYIEFLT-DMLFTKCTDEFARAIANHSVPTYEYLFDYR-GQYSIVNFQGEQVDMGVVHGDEMQYVF 456          

Query:  282 LIKKTQEGSIKGVNLSPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTTGYSGADLWNTQEELSEDCLYLNIYAPKNATKAL------------PVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWA----YAEPEEARERARNLSQLLDCPSDPDEIVGCLREKDAKDLVAKE--FDGAPSAINSYPFG----PTLDGDFITESPEKALTSGLISSKIP-VLLGSNANEGFYSLMYFD-PDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDH-----------RSSQDPWP------------EYTGSKHGDEIEFMFGVPLETPELYMAKEV--GLAEDMVTYWLNFVKAGNPNPSVFLESW-PRYQEPDWSYLNL 780
            LI  +  G ++G       +A+ G+P+A  P G+ RF  P       +  +   R  P +C Q L +  Y  + LW+   E +EDCLYLNI++P +A+  L            PV VWIHGG   +G+AS   Y+    ++  +++ V I YRLG LGF+ LGE     GN G  DQ+ AL WIQ+NI +FGG+P+ VT+ GESSGA S   HM  P S+ LF   I+QS ++  P        E  EA         ++D          C+++     +V K           N +PF     P L+G ++     K +++    S  P V++G+ +NEGF +   F   + + +  + + ++        D    + P   ++     K ++   +++           +  DF +        ++++  G+ VY Y +DH           R+S D W             +  G+ H DE+ F+F    E P   + + V   +   M+  W NF  +G+PN +    +W P   + D++Y+ L
Sbjct:   35 LIVHSPSGLVQGAREKGH-QAFYGIPYALPPTGERRFRSPEPYPTPWKRTLQAGRSYPPACPQQLRS--YFKSLLWDV--EGNEDCLYLNIFSPDSASLQLSNESPPSQENLFPVMVWIHGGNFMSGTAS--DYESIYFMTK-DIILVMISYRLGPLGFLNLGE-EYARGNQGIEDQILALSWIQDNISSFGGDPQRVTIFGESSGAISVLHHMSVPMSKLLFQSAIIQSGSIYQPTIKETFMMEMHEAWIAEMGCIGVIDTQE-------CIQKLPLAKIVNKNPFLSDCNLKKNGHPFPNPWFPVLEGSYLL----KEVSAENKKSHAPRVMIGTTSNEGFLATSRFMLQNNYTEGFMSKWEECFKLNTAGDESYDLEPVMDYYFGSNKKPDFPSQVQN--------FSNLISDFWYNGPTFETVKEIANKGSPVYYYLYDHDGFLSMTDSLSRASYDYWKFIVRYAFGQESGKTNGASHADELPFLFR---EYPRNLLKRPVDEKMWRLMIDVWTNFATSGDPNGAKEGYNWKPVSHKNDYTYIVL 552          

Query:  302 AWLGVPFAQAPVGDLRFAPPVDAEPSSE--DDVLNTRRQPKSCMQNLDTTGYSGADLWNTQEELSEDCLYLNIYAPKNATK--ALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISP-KSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDEIVGCLREKDAKDLVAK--EFDGAPSAINSYPFGPTLDGDF-----ITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYF--DPD-------TFPDQELDEDDQDLSEK--DFNDVVQAIFP---QFPFFVRELIKHEYRDLIRSGGKGRFKALDR----------------MAGDFAFVCDVE-GFAQDLSENGNQVY-RYHFDHRSSQDPWPEYTGSKHGDEIEFMFGV-----PLET-PELYMAKEVGLAEDMVTYWLNFVKAGNPNP-SVFLE---SWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLM 809
            ++ G+P+A  P+G+ RFA P   EP S   + + +  + P  C+Q  D    +  D         EDCL LNI  P   T+    PV +W+HGG ++  S S   ++    +    V+F+ I YRLG +GF+ L E    PGN+G  DQ  A++WI++ I    GN + +TL+G  SGA+SA +H++SP   +G F ++I QS +          +  +E A+ L+  + C     EI+ CLR + A  L  K   F+         P+ P +D  F     + + PE  + +   S  IP+L GS A EG   +  F   P+       T P    + +D+ ++ K  D  ++V+  F    Q  +   + I   + D++  G  GR   L R                  GD +F  D + G    L   G  ++ R  F             G+ HGDE+  +F +     P+ + P     K VG  + ++T W+NF + GNP P   FL+    W   QE +     + T       E   L +R  F++ +   L 
Sbjct:   60 SYFGLPYALPPLGERRFARP---EPYSNAWEGIRDGTQSPPICVQQ-DIHRNNPNDTIGV-----EDCLVLNINQPLTCTRENRCPVIIWLHGGSYALLSGSPYTFNPLYFMDHN-VIFIGINYRLGAMGFLTL-ETDEAPGNLGLRDQSLAIKWIRDEIDNLYGNKDQITLMGHGSGAHSALIHLVSPFNKKGTFTRIITQSGSPFEDTNLRFAKSRKEYAKKLAASVGCTK---EILKCLRSRPADILQTKVQTFNIINQVFTPNPWVPVIDIKFAHDPVLPDYPENIVKNTNFSRSIPILTGSVAEEGMLLMKRFFQHPELFAQFTRTLPFLLFNLEDESVTPKVQDLVEIVKKFFIPKGQLSYSQNKQIIAMFTDMVFYGKIGRAIQLLRDHGPIYQYIYKYFGTHSFGDLSFYSDFKLGLKLSLQSRGIGLFMRNGF-------------GTCHGDELFDIFKIGFLKAPMSSGPISDFDKSVG--QSLITMWINFARTGNPTPMGYFLDDNSKWLSIQESNGMVAEIKTKTR--MIEDTFLEKRVNFYHRVFEYLF 590          

Query:  289 GSIKGVNLSPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTTGYSGADLWNTQEELSEDCLYLNIYAPKNAT-KALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVI-LQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD---EIVGCLREKDAKDLVA--------KEFDGAPSAINSYPFGPTLDGD----FITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFN-DVVQAIFPQFPFFVRELIKHEY--RDLIRSGGKGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHR 702
            G+I+      ++ A+ G+   + PVGDLRF  PV       D +   ++    C Q++    Y   D+W  +E    DCL+LN+++   A  K  PV VWIHGG    G A+   Y+   ++   ++V V IQYRLG+ GF+   E    PGN G LDQV ALQW++ NI  F G+   +T++G+ +G  S   HM+S  S GLFH+ I L  SAL+  W +A  +   ERA+ L++LL+CP D D   E++ C+R  + + ++         K  +     +N++   P +D +    F+   P   +T+G     +P + G   +EG +    F  +    +E +ED + +    F     Q+  P+     R+++ + +  ++L +   K    AL      +A   D     Q +      VY YHF ++
Sbjct:   98 GTIEETRTGGRILAFRGIRHVRPPVGDLRFKAPVPF--PRWDGIREAKKNGHFCPQHM----YYKPDVWIGEE----DCLWLNVFSRDLAVNKKRPVIVWIHGGNFVRGXAA--DYEPDYLLDE-DIVLVTIQYRLGMFGFL-SSEDQYAPGNYGMLDQVAALQWVKTNIDAFSGDVNHITIMGQQAGGASVHYHMLSSLSRGLFHRAISLSGSALS--W-WASLKRPLERAKKLARLLECPYDADKSKEMIECIRGIEMEKMMNTHPNFYEWKHLNQNQEPVNAW--SPRVDPEAALSFMPNEPIDLMTAGNF-QHVPWIAGITDDEGAFKGSAFFSEMRNVREFEEDFEKIGPLMFGFHDGQSEAPK--MMARKVMDYYWNGKELTKENAKSLVDALS--XSSYAHPVDXASKIQSIKSQA-PVYVYHFGYK 506          

Query:  365 EDCLYLNIYAP----KNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDEIVGCLREKDAKDLVAKEFDGAPSAINSYP--FGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDF---------NDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQ-VYRYHFDHRSSQ 705
            EDCLYLN+Y P        K  PV VWI+GG +  G AS   Y    ++  G VV V + YRLG LGF+ LG  T +PGNMG  DQ  A++WI+ +IG FGG+ +++TL+G  +G+     HM+S  S GLFHK I  S                                      + EK + D+        P+++NS    F    D  F +ES  + + +G   +K+P+L+G++ + G   +         +    ED++D   +D+         N     + PQ        +K  Y D       G F  L    GD  F+   + F + +     Q +Y Y+FDH  S 
Sbjct:   35 EDCLYLNVYTPDLPVTENQKKFPVIVWIYGGNYLWGDASERFYFPKYLIESGSVVIVTLNYRLGPLGFLTLGNET-VPGNMGLWDQRLAMEWIRTHIGNFGGDADEITLMGHDAGSVCITNHMVSKSSAGLFHKAICMSGTF-----------------------------------VSEKFSFDV------SDPASLNSIKEEFAKECDKSFFSESQLETIKTGEF-NKMPILMGTSRHSGIALI--------SEAIGSEDNKDRLRRDWTVLGGELILNRPENILRPQEDLQFVNTLKKFYFDQEEFTEDGGFDQLINAVGDAVFLGANDYFIKAVHGGSAQPIYLYNFDHMYSN 340          

Query:  286 TQEGSIKGVNL---SPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSE-DDVLNTRRQPKSCMQNLDTTGYSGADLWNTQEELSEDCLYLNIYAP---KNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSAL---------NAPWAYAEPEEARERARNLSQLLDCPSDPDEIVGCLREKDAKDLVAKEFDGAPS-AINSYPFGPTLDGDFITESPEKALTSGLISSKI---------PVLLGSNANEGFYSLM 605
            T  G +KG  L      + ++ GVP+A  P    RF+    A+P S+    L+  ++ K   Q  +   +    L++      +DCLYLN++ P   +++   LPV V+ HGG    G      Y    ++S   +V V + +RLG  GF+   + ++ PGN G  DQ+ +L W+Q++I  FGG   +VT++G+ +G  S+  H+ SP S+GLFHK+I  S A+           PW YA+   A     N++Q        D I+  LR   AK +++K F       + S P+ P +DG ++T  PE +       + +          +L+G  A +G  SL+
Sbjct:   19 TSLGKLKGKTLLMNDKHIYSFTGVPYADKPQ---RFSL---AKPCSKWTGTLDCTKESKMGYQP-NPMFFESTFLYHG---FPDDCLYLNVFTPILKEDSFDLLPVIVYFHGGAFILGGNDTKIYGPEILLSTQNMVLVTVNFRLGPFGFLSF-QNSDCPGNQGMHDQILSLMWVQSHIHHFGGTSSNVTIMGQXAGGMSSLYHLASPLSKGLFHKIICLSGAVMYAPFVHIDRDPWDYAK-AFAESLGVNVNQ------SVDNILTQLRSISAKTILSKTFLFKDVFLLASCPWKPCVDGGYLT--PETSFLPDTFINLVSQGKGNPVESILMGYTAQDGLSSLI 344          

Query:  368 LYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPG---NMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDC-PSDP------------------------------------------------DEIVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQA-IFPQFPFFVREL---IKHEYRDL---IRSGGKGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEY-TGSKHGDEIEFMFGVPLET------PELYMAKEVGLAEDMVTYWLNFVKAGNPN 759
             +  I   +   KA PV V++HG     GS +L  +D   + + GEVV +   YRLGVLGF+ L +     G   N G +DQ+  LQWIQ N  +F G+ + VTL G  +               GLFH+VIL S +L APW+     E  + A  L++  DC  SD                                                 ++I+ CLR+K A+DL+A + +  PS      FGP+ DG  +T     A   G  S       G+   E    ++    D F D   +E  + +     + ++Q  +  Q+   ++E+   +++EY D    ++     R + L   + D  +V                 + YHF H++   P+ +Y  GS HG E++++FG+PL+          Y   E  L++ ++ YW NF K+G+PN
Sbjct:    4 FFFQIRILEKXKKAYPVMVYVHGESFKWGSGNL--WDARILAAFGEVVVITFNYRLGVLGFLNLNDSPLRRGQVANYGIMDQMAVLQWIQENAESFNGDSKRVTLFGHGT---------------GLFHRVILMSGSLFAPWSRV--REPLDYALQLAKKFDCIESDSSKGKRKEDVKRTFPHEGEDSPINMAVENSISHQHNRRRKMSSRLRGGNNDIISCLRKKSAEDLMAIDLN-VPSF--HLDFGPSFDG--VTIKDNFADIKGKRS------FGTRTYEAIVGVV--THDYFNDLSDEEVRRGIGLNVRDRMLQTFVRNQYKAHLQEILLTLQNEYTDWAESVQHPSIVREQVLQAFS-DGLYVSPAVFSVGTFFRKSKNTFFYHFSHQTKGGPFSQYKIGSTHGSELQYVFGIPLKNIWNSFITYSYTRNEALLSQIIMKYWTNFAKSGDPN 428          

Query:  363 LSEDCLYLNIYAP----KNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISP--KSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPS-----DPDEIVGCLREKDAKDLVA----------KEFD-----GAPSAI---NSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYS 603
            +SEDCL+L I  P       +K  PV  ++HGGG S+G+      D  ++    +V+ VAI YR+G+LGF+ L +     GN G LD + AL+W+Q  I  FGG+ E VT+ GES+G+ +    ++SP  + + LF   I QS +  +PWA+    E R      ++ L C +     D D IV CLR  +  ++            K FD      +P A    +   +GP  D       P + L SG  ++++P+  G+N  EG Y+
Sbjct:  188 MSEDCLHLTISTPVKPPPKESKGYPVMFFVHGGGFSSGTHLHSEAD--RLGDAADVIVVAINYRVGILGFLCL-DSDESAGNQGMLDILLALEWVQKYIEHFGGDKERVTIFGESAGSATIGHLLLSPSTREKNLFKYGIGQSGSAISPWAFD--REPRRSGYEFAERLGCKTINENEDDDSIVKCLRNFEDWEITKEFSLFTTERRKHFDLGFGGSSPCAQTKGDKKFYGPKDD-------PMEILYSGDYNTEVPIFFGNNLYEGIYT 445          

Query:  281 ELIKKTQEGSIKGVNL---SPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD-EIVGCLREKDAKDLVAKEFDGAPS-AINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPSVFLES-WPRYQEPDWSYLNLTT----AYNGGRAEKGTLSQRCKFWNELLNSLMKALG 813
            ++I  T+ G ++G+NL      V A+LG+P+AQ P+G LRF  P      S  D+ N  +   SC QN D +  G+ G+++WN   +LSEDCLYLN+++P    K   V +WI+GGG  TG++SL  YDG  +     V+ V++ YR+G LGF+ L     IPGNMG  DQ  ALQW+Q NI  FGGNP+ VTL GES+GA S ++H++SP+S+ LF + ILQS + NAPWA    +EA+ R   L++ + C  + D EI+ CLR KD ++++  E    PS  + S  FGP +DGDF+T+ P+  L  G    K  +L+G N +EG   L+Y  P    D     +D  ++ K+F + ++  FP    F RE I   Y DL+      +++ ALD + GD+  +C    F    SE GN  + Y+F+HRSSQ PWPE+ G  HG EIEF+FG+PLE    Y   E  L+  ++ YW NF K GNPN +    + WP ++  D  YL L       Y   RA      Q+C+FW      +++  G
Sbjct:   31 DIIITTKNGKVRGMNLPVLDGTVTAFLGIPYAQPPLGRLRFKKPQFLTKWS--DIWNATKHANSCYQNADQSFPGFPGSEMWNPNTDLSEDCLYLNVWSPTPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEIPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAGSVSLHLLSPRSQPLFTRAILQSGSSNAPWAVMSLDEAKNRTLTLAKFIGCSKENDTEIIKCLRNKDPQEILLNELLVVPSDTLLSVNFGPVVDGDFLTDMPDTLLQLGQF-KKTQILVGVNKDEGTAFLVYGAPGFSKD-----NDSIITRKEFQEGLKIYFPGVSEFGREAILFYYVDLLDDQRAEKYREALDDVLGDYNIICPALEFTTKFSELGNNAFFYYFEHRSSQLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMNYWANFAKYGNPNGTQNNSTRWPAFRSTDQKYLTLNAESPKVYTKLRA------QQCRFWTLFFPKVLEMTG 562          

Query:  281 ELIKKTQEGSIKGVNL---SPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD-EIVGCLREKDAKDLVAKEFDGAPS-AINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPSVFLES-WPRYQEPDWSYLNLTT----AYNGGRAEKGTLSQRCKFWNELLNSLMKALG 813
            ++I  T+ G ++G+NL      V A+LG+P+AQ P+G LRF  P      S  D+ N  +   SC QN D +  G+ G+++WN   +LSEDCLYLN++ P    K   V +WI+GGG  TG++SL  YDG  +     V+ V++ YR+G LGF+ L     +PGNMG  DQ  ALQW+Q NI  FGGNP+ VTL GES+GA S ++H++SP+S+ LF + ILQS + NAPWA    +EA+ R   L++ + C  + D EI+ CLR KD ++++  E    PS  + S  FGP +DGDF+T+ P+  L  G    K  +L+G N +EG   L+Y  P    D     +D  ++ K+F + ++  FP    F RE I   Y DL+      +++ ALD + GD+  +C    F    SE GN  + Y+F+HRSSQ PWPE+ G  HG EIEF+FG+PLE    Y   E  L+  ++ YW NF K GNPN +    + WP ++  D  YL L       Y   RA      Q+C+FW      +++  G
Sbjct:   31 DIIITTKNGKVRGMNLPVLDGTVTAFLGIPYAQPPLGRLRFKKPQFLTKWS--DIWNATKYANSCYQNADQSFPGFPGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEVPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAGSVSLHLLSPRSQPLFTRAILQSGSSNAPWAVMSLDEAKNRTLTLAKFIGCSKENDTEIIKCLRNKDPQEILLNELLVVPSDTLLSVNFGPVVDGDFLTDMPDTLLQLGQF-KKTQILVGVNKDEGTAFLVYGAPGFSKD-----NDSIITRKEFQEGLKIYFPGVSEFGREAILFYYVDLLDDQRAEKYREALDDVLGDYNIICPALEFTTKFSELGNNAFFYYFEHRSSQLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMNYWANFAKYGNPNGTQNNSTRWPAFRSTDQKYLTLNAESPKVYTKLRA------QQCRFWTLFFPKVLEMTG 562          

Query:  281 ELIKKTQEGSIKGVNLSP---QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD-EIVGCLREKDAKDLVAKEF----DGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPSV-FLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKALG 813
            ++I  T+ G ++G+NL+     V A+LG+P+AQ P+G LRF  P      S  D+ N  +   SC QN+D +  G+ G+++WN   +LSEDCLYLN++ P    K   V +WI+GGG  TG++SL  YDG  +     V+ V++ YR+G LGF+ L      PGNMG  DQ  ALQW+Q NI  FGGNP+ VTL GES+GA S ++H++SP S  LF + ILQS + NAPWA     EAR R  NL++L  C  + + EI+ CLR KD ++++  E      G P ++N   FGPT+DGDF+T+ P+  L  G    K  +L+G N +EG   L+Y  P    D     ++  ++ K+F + ++  FP    F +E I   Y D +       ++ AL  + GD+ F+C    F +  SE GN  + Y+F+HRSS+ PWPE+ G  HG EIEF+FG+PLE  + Y   E  L+  +V  W NF K GNPN +     SWP ++  +  YL L T     R      +Q+C+FW      +++  G
Sbjct:   31 DIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS--DIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVN---FGPTVDGDFLTDMPDILLELGQF-KKTQILVGVNKDEGTAFLVYGAPGFSKD-----NNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNT--ESTRIMTKLRAQQCRFWTSFFPKVLEMTG 562          

Query:  281 ELIKKTQEGSIKGVNL---SPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD-EIVGCLREKDAKDLVAKEFDGAP-SAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPSVFLES-WPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKALG 813
            ++I  T+ G I+G+NL      V A+LG+P+AQ P+G LRF  P      S  D+ N  +   SC QN+D +  G+ G+++WN   +LSEDCLYLN++ P    K   V +WI+GGG  TG++SL  YDG  +     V+ V++ YR+G LGF+ L      PGNMG  DQ  ALQW+Q NI  FGGNP+ VTL GES+GA S ++H++SP+S  LF + ILQS + NAPW      EAR R   L++ + C ++ + EI+ CLR KDA++++  E    P  ++ S  FGPT+DGDF+T+ P+  L  G +  K  +L+G N +EG   L+Y  P    D     +   ++ K+F + ++  FP    F +E I   Y D +       ++ ALD + GD+ F+C    F +  SE GN  + Y+F+HRSS+ PWPE+ G  HG EIEF+FG+PLE    Y   E  L+  ++  W NF K GNPN +    + WP ++  +  YL L T     R      +Q+C+FW      +++  G
Sbjct:   10 DVIITTKNGRIRGINLPVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS--DIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGGFQTGTSSLQVYDGKFLTRVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPRSHPLFTRAILQSGSSNAPWEVMSLHEARNRTLTLAKFVGCSTENETEIIKCLRNKDAQEILLNEVFVVPFDSLLSVNFGPTVDGDFLTDMPDTLLQLGQL-KKTQILVGVNKDEGTAFLVYGAPGFSKD-----NTSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDEQRPENYREALDDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEILSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSTEQKYLTLNT--ESPRIYTKLRAQQCRFWTLFFPKVLEMTG 541          

Query:  274 DLNDDDPELIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDEI---VGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPN---PSVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            D  D DP L+  T +G I+G  L      +V AW+G+P+AQ P+G LRF  P  AE  +   VLN  + P SC+Q +DT    + GA +WN    LSEDCLY+N+  P+   K   V +WI GGG  +G+A+LD YD   + S   V+ V++QYR+  LGF+FLG     PGN G  DQ  AL+W+++NI  FGG+P  VTL GES+GA S ++H++S  S  LF + ILQS +  APWA    EEA  RA  L++ ++CP D  ++   V CLR KD  +LV  E+      I  +PF P +DG F+ E+P+++L SG    K  +L GSN  EG+Y ++Y+      +    E+   ++ ++F   V+ + P      R+ I  EY D I        + ALD+M GD+ F C+V  FAQ  +E GN V+ Y + HRS  +PWP +TG  HGDEI ++FG PL +   Y   E   +  ++ YW NF K GNPN   PSV L  WP++      YL L    N     +G   ++C FW + L  L+ A
Sbjct:  126 DATDSDP-LVITTDKGKIRGTTLEAPSGKKVDAWMGIPYAQPPLGPLRFRHPRPAERWT--GVLNATKPPNSCVQIVDTVFGDFPGATMWNPNTPLSEDCLYINVVVPRPRPKNAAVMLWIFGGGFYSGTATLDVYDHRTLASEENVIVVSLQYRVASLGFLFLGT-PEAPGNAGLFDQNLALRWVRDNIHRFGGDPSRVTLFGESAGAVSVSLHLLSALSRDLFQRAILQSGSPTAPWALVSREEATLRALRLAEAVNCPHDATKLSDAVECLRTKDPNELVDNEWGTL--GICEFPFVPVVDGAFLDETPQRSLASGRFK-KTDILTGSNTEEGYYFIIYY----LTELLRKEEGVTVTREEFLQAVRELNPYVNGAARQAIVFEYTDWIEPDNPNSNRDALDKMVGDYHFTCNVNEFAQRYAEEGNNVFMYLYTHRSKGNPWPRWTGVMHGDEINYVFGEPLNSALGYQDDEKDFSRKIMRYWSNFAKTGNPNPSTPSVDLPEWPKHTAHGRHYLEL--GLNTTFVGRGPRLRQCAFWKKYLPQLVAA 663          

Query:  274 DLNDDDPELIKKTQEGSIKGVNL----SPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDEI---VGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNP---SVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            D ND+DP L+  T +G I+G+ +      +V  WLG+P+AQ PVG LRF  P  AE  +   VLNT   P SC+Q +DT    + GA +WN    LSEDCLY+N+ AP+   K   V +WI GGG  +G+A+LD YD   + S   V+ V++QYR+  LGF+FLG     PGN G  DQ  AL+W+++NI  FGG+P  VTL GES+GA S ++H++S  S  LF + ILQS +  APWA    EEA  RA  L++ + CP +P ++   V CLR KD   LV  E+      I  +PF P +DG F+ E+P+++L SG    K  +L GSN  EG+Y ++Y+  +        E+   ++ ++F   V+ + P      R+ I  EY D          + ALD+M GD+ F C+V  FAQ  +E GN VY Y + HRS  +PWP +TG  HGDEI ++FG PL     Y   E   +  ++ YW NF K GNPNP   S     WP++      YL L    N     +G   ++C FW + L  L+ A
Sbjct:  159 DANDNDP-LVVNTDKGRIRGITVDAPSGKKVDVWLGIPYAQPPVGPLRFRHPRPAEKWT--GVLNTTTPPNSCVQIVDTVFGDFPGATMWNPNTPLSEDCLYINVVAPRPRPKNAAVMLWIFGGGFYSGTATLDVYDHRALASEENVIVVSLQYRVASLGFLFLGT-PEAPGNAGLFDQNLALRWVRDNIHRFGGDPSRVTLFGESAGAVSVSLHLLSALSRDLFQRAILQSGSPTAPWALVSREEATLRALRLAEAVGCPHEPSKLSDAVECLRGKDPHVLVNNEWGTL--GICEFPFVPVVDGAFLDETPQRSLASGRFK-KTEILTGSNTEEGYYFIIYYLTELL----RKEEGVTVTREEFLQAVRELNPYVNGAARQAIVFEYTDWTEPDNPNSNRDALDKMVGDYHFTCNVNEFAQRYAEEGNNVYMYLYTHRSKGNPWPRWTGVMHGDEINYVFGEPLNPTLGYTEDEKDFSRKIMRYWSNFAKTGNPNPNTASSEFPEWPKHTAHGRHYLEL--GLNTSFVGRGPRLRQCAFWKKYLPQLVAA 696          

Query:  281 ELIKKTQEGSIKGVNL---SPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD-EIVGCLREKDAKDLVAKEFDGAP-SAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPSVFLES-WPRYQEPDWSYLNLTT----AYNGGRAEKGTLSQRCKFWNELLNSLMKALG 813
            ++I  T+ G ++G+NL      V A+LG+P+AQ P+G LRF  P      S  ++ N  +   SC QN D +  G+ G+++WN   ELSEDCLYLN++ P    K   V +WI+GGG  TG++SL  YDG  +     V+ V++ YR+G LGF+ L E    PGNMG  DQ  ALQW+Q NI  FGGNP  VTL GES+GA S ++H++SP+S+ LF + ILQS + NAPWA     EAR R   L++ + C  D + E++ CLR+KD ++++  E    P   + S  FGPT+DGDF+T+ P+  L  G    +  +L+G N +EG   L+Y  P    D     ++  ++ K+F + ++  FP+   F RE I   Y D +       ++ ALD + GD+  +C    F +  SE GN  + Y+F+HRS++ PWPE+ G  HG EIEF+FG+PLE    Y   E  L+  ++  W NF K GNPN +    + WP ++  +  YL L T     Y   RA      Q+C+FW      +++  G
Sbjct:    3 DIIITTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS--NIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLTDMPDTLLQLGQF-KRTQILVGVNKDEGTAFLVYGAPGFSKD-----NNSIITRKEFQEGLKIFFPRVSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTRKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSTEQKYLTLNTESPKVYTKLRA------QQCRFWTLFFPKVLELTG 534          

Query:  281 ELIKKTQEGSIKGVNLSP---QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD-EIVGCLREKDAKDLVAKEFDGAP-SAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNP-NPSVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            EL   TQ GS++G++L      V A+LG+PFA+ P+G +RF  P   +P     VL+      +C Q +DT+  G+ G ++WN    +SEDCLYLNI+ P    K  PV VWI+GGG  +G+ASLD YDG  +     V+ V++ YR+G  GF+ L      PGNMG LDQ  ALQWIQNNI  FGGNP  VT+ GES+GA S  MH++S +S  LF + ILQS   NAPWA   P E+R RA  L + L C  + D E+V CLR K+ ++L+ +E+   P  +I  +PF P +DGDF  ++PE  L+SG    +  VLLG   +EG Y L+Y  P    D E       +S  DF + V+   P       + +  +Y D      + + + ALD + GD   +C V  FA D ++  ++VY Y FDHR+S   WP + G  HG EIEF+FG+PL     Y  +E  L+  M+ YW NF + GNP +P+    +WP Y      Y+ L T       +    +Q C FWN  L  L+ A
Sbjct:   36 ELKVSTQTGSVRGLSLPVLDGHVSAFLGIPFAEPPLGRMRFLRPEPVKPWQH--VLDATSYKPACYQMVDTSYPGFQGTEMWNPNRGMSEDCLYLNIWVPSPRPKDAPVLVWIYGGGFYSGAASLDVYDGRFLTYTQNVILVSLSYRVGAFGFLGLPGSPEAPGNMGLLDQRLALQWIQNNIHPFGGNPRAVTVFGESAGAASVGMHLLSTQSRTLFQRAILQSGGPNAPWATVTPAESRGRAALLGKQLGCHFNNDSELVSCLRSKNPQELIDEEWSVLPYKSIFRFPFVPVIDGDFFPDTPEAMLSSGNF-KETQVLLGVVKDEGSYFLIYGLPGFSKDNE-----SLISRADFLEGVRMSVPHANDIATDAVVLQYTDWQDQDNREKNREALDDIVGDHNVICPVVQFANDYAKRNSKVYAYLFDHRASNLLWPPWMGVPHGYEIEFVFGLPLNDSLNYTPQEKELSRRMMRYWANFARTGNPTDPADKSGAWPTYTASQPQYVQLNT--QPLATQPSLRAQICAFWNHFLPKLLNA 565          

Query:  281 ELIKKTQEGSIKGVNL---SPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD-EIVGCLREKDAKDLVAKEFDGAP-SAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPSVFLES-WPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKALGVAKDV 818
            ++I  T+ G ++G++L      V A+LG+P+AQ P+G LRF  P     +   D+ N  +   SC QN D +  G+ G+++WN   +LSEDCLYLN++ P    K   V +WI+GG   TG++SL  YDG  +     V+ V++ YR+G LGF+ L      PGN+G  DQ  ALQW+Q NI  FGGNP+ VTL GES+GA S ++H++SP+S  LF + ILQS + NAPWA     EAR R   L++ + C  + D EI+ CLR KD ++++  E    P   + S  FGPT+DGDF+T+ P+  L  G    K  +L+G N +EG   L+Y  P    D     ++  ++ K+F + ++  FP    F +E I   Y D +      +++ ALD + GD+  +C    F +  S+ GN  + Y+F+HRSS+ PWPE+ G  HG EIEF+FG+PLE    Y   E   +  ++  W NF K GNPN +    + WP ++  +  Y  L T     +      +Q+C+FW      +++  G   +V
Sbjct:   31 DIIITTKNGKVRGMHLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSL--TKWPDIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGSFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNVGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPESHPLFTRAILQSGSSNAPWAVTSRYEARNRTLTLAKFIGCSRENDTEIIKCLRNKDPQEILRHEVFVVPYGTLLSVNFGPTVDGDFLTDMPDTLLQLGQF-KKTQILVGVNKDEGTAFLVYGAPGFSKD-----NNSIITRKEFQEGLKIFFPGVSEFGKESILFHYMDWLDDQRAEKYREALDDVVGDYNIICPALEFTKKFSDMGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEIFSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSNEQKYFTLNT--ESPKVNTKLRAQQCRFWTLFFPKVLEITGNIDEV 567          

Query:  278 DDPELIKKTQEGSIKGVNL-SP--QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDT--TGYSGADLWNTQEELSEDCLYLNIYAP-KNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCP-----SDPDEIVGCLREKDAKDLVAKEFDGAPS-AINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPN----PSVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            +DPEL+   + G ++GV L +P   V A+LG+PFA+ PVG  RF PP    P     VL+       C Q +DT   G+ G ++WN   ELSEDCLYLN++ P        PV VWI+GGG  +G++SLD YDG  +      V V++ YR+G  GF+ L      PGN+G LDQ  ALQW+Q+N+ TFGG+P  VTL GES+GA S  MH++SP S GLFH+ +LQS A N PWA     EAR RA  L++L+ CP      +  E+V CLR + A+DLV  E+   P  ++  + F P +DGDF++++PE  + +G     + VL+G   +EG Y L+Y  P    D E       +S   F   V+   PQ      E +   Y D +      R + A+  + GD   VC V   A  L+  G +VY Y F+HR+S   WP + G  HG EIEF+FG+PLE    Y A+E   A+ ++ YW NF + G+PN    P V    WP Y      Y++L          +G  +Q C FWN  L  L+ A
Sbjct:   32 EDPELLVTVRGGQLRGVRLMAPGGPVSAFLGIPFAEPPVGPRRFLPPEPKRPWP--GVLDATAFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLVWIYGGGFYSGASSLDVYDGRFLAQAEGTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQDNVATFGGDPMSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELVACLRTRPAQDLVDHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHG-LQVLVGVVKDEGSYFLVYGAPGFSKDNE-----SLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLNPEDPARLREAMSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYEIEFIFGLPLEPSLNYTAEERIFAQRLMRYWANFARTGDPNDPRDPKV--PQWPPYTAGAQQYVSLDL--RPLEVRRGLRAQACAFWNRFLPKLLSA 570          

Query:  199 MVEDLKDKQKLVNLRDQMLQVLFSSEG-KLISGSPLMTAERRVNIQTGNGVIHGVSEVIYPFKSN-DEMKLKTKRVLDLNDDDPELIKKTQEGSIKGVNLSPQVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTTGYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDEIVGCLREKDAKDLVAKEFDGAPS-AINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPSVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKAL 812
            M EDLKD+Q LVNLRDQML+VLF+ +  KLISGS LMT ERRVNIQ  NG+IHG+S+VIYPF S  D M  KTKR L ++DDDPELIKK ++G++KG+NLS  VRAWLGVP+AQ PVG+LRFAPP D E   +DD L TR QP SCMQNLDT+G +GA++WNT+EELSEDCLYLNIYAP+NAT+ LPV VWIHGGGHSTG+ASLD+YDG Q+VS G +VFVAIQYRLG LGFM+LGE + IPGNMG LDQVKAL WI  NI TF GNP++VTL+GESSGA+S A+HMISPKSEGLF K IL SS LN  W Y  P+ A E ARNLS LLDCP DP++I+ CLREKDA+++ +K  +  P  A  ++PF  TLDG+FITE P++AL + +ISSKIPVLLGSNANEGF+ L+   PDTFPD+ELD  D ++SE+D  D ++++FPQ+P F++ LI+HEY+D+I S   G+F ALD++ GD A+VCD E FAQ +SENGN VYR+HF+H+SSQDPWPEYTGSKHGDEIEF+FG PLE P  Y  +E+ LA DM+TYWLNFVK GNPNPS  L SWP+YQEP W YLNLT  +NGG+  + TL+ RC+FWNE+L SL+K L
Sbjct:    1 MAEDLKDRQSLVNLRDQMLKVLFAKDDDKLISGSKLMTQERRVNIQANNGIIHGISDVIYPFTSKGDMMNAKTKRFLAIDDDDPELIKKVKQGTLKGINLSRHVRAWLGVPYAQPPVGELRFAPPEDLEERDDDDTLETRSQPNSCMQNLDTSGMTGAEMWNTKEELSEDCLYLNIYAPRNATELLPVLVWIHGGGHSTGAASLDQYDGQQLVSSGNIVFVAIQYRLGPLGFMYLGERSGIPGNMGLLDQVKALDWISQNIQTFNGNPDEVTLMGESSGAHSVALHMISPKSEGLFQKAILHSSGLNPSWGYQAPKNALENARNLSSLLDCPEDPEDILTCLREKDAEEITSKAKEVLPKEAFLTFPFVVTLDGNFITEEPQEALANEVISSKIPVLLGSNANEGFFDLLTNKPDTFPDKELDLRDMEMSEEDIEDQIKSLFPQYPAFIQRLIRHEYKDVISSSMAGKFHALDQIVGDSAYVCDTEHFAQAISENGNDVYRFHFNHQSSQDPWPEYTGSKHGDEIEFIFGRPLENPNKYEVEELSLASDMMTYWLNFVKTGNPNPSSLLASWPKYQEPCWPYLNLTAEFNGGKVFERTLNGRCEFWNEILPSLLKEL 617          

Query:  264 EMKLKTKRVLDLNDDDPELIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDEI---VGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLIS---SKIPVLLGSNANEGFYSLMYFDPDTFPDQELD-EDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPN----PSVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKALGVAK 816
            E  L     L+LN DD EL+ +T++G ++GV L+     +V AW+G+P+AQ P+G LRF  P  AE    D +LNT   P SC+Q LDT    + GA +WN    LSEDCLY+N+  P+       V VWI GGG  +G+A+LD YD   +VS   V+ V++QYRL  LGF++ G G ++PGN G  DQV ALQW+++NIG FGGNP++VTL GES+GA S + H++SP S  LF + I+QS +  APWA    EE++ R   L++ L CP +   +   V CLR KD  DLV  E+      I  +PF P +DG F+ E+P+++L S   +    +  +L+GSN  EG+Y ++Y+  + F    +D  +D  +S  +F   V+ + P      R  I +EY D +R     R + ALD++ GD+ F C+V  FA   +E GN VY Y++ HRS+ +PWP +TG  H DEI ++FG PL++   Y  +EV L++ M+ YW NF K GNPN     S    +WP +      YL L T  N      G  S++C FW + L  L+ A    K
Sbjct:   55 EHPLPKPESLNLNPDD-ELVVRTRKGKVRGVTLTATTGKKVDAWMGIPYAQKPLGPLRFRHPRPAE--RWDGILNTTTPPNSCVQILDTVFGDFPGATMWNPNTPLSEDCLYVNVVTPRPRPTNAAVMVWIFGGGFYSGTATLDVYDHRTLVSEENVILVSMQYRLASLGFLYFGTG-DVPGNAGLFDQVLALQWVRDNIGAFGGNPDNVTLFGESAGAVSVSFHLLSPLSRNLFSQAIMQSGSPTAPWAMISREESKVRGLRLAEALGCPHEESALSSAVECLRSKDPFDLVNNEWGTL--GICEFPFVPVIDGAFLDETPQRSLASSPTNPSFKRANILMGSNTEEGYYFIIYYLTELF---RIDGTEDVKVSRDEFLRAVRELNPYVNQIARNAIVYEYTDWLRPDDPYRNRDALDKIVGDYHFTCNVNEFAARYAETGNTVYMYYYTHRSANNPWPSWTGVMHADEISYIFGEPLDSSRGYTREEVYLSKRMMRYWANFAKTGNPNMGDDGSWAETTWPEHTFAKREYLTLAT--NSTEIGYGPRSKQCAFWKKYLPQLIAATANMK 614          

Query:  263 DEMKLKTKRVLDLNDDDPELIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDP---DEIVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELD-EDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPN---PSVFLES-WPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKALGVAK 816
            D   L     L+LN +D +++ +T++G ++G+ L+     +V AW+G+P+AQ P+G LRF  P  AE    + +LNT   P SC+Q LDT    + GA +WN    LSEDCLY+N+  P+       V VWI GGG  +G+A+LD YD   IVS   V+ V++QYRL  LGF++ G G ++PGN G  DQV ALQW+++N+  FGGNPE+VTL GES+GA S ++H++SP S  LF++ I+QS +  APWA    EE+R R   L++ + CP +     E V CLR KD  DLV  E+      I  +PF P +DG F+ E+P+++L++     +  +L+GSN  EG+Y ++Y+  + F    +D  +D  ++ ++F   V+ + P      R  I +EY D +R     R + ALD++ GD+ F C+V  FA   +E GN VY Y++ HRS+ +PWP +TG  H DEI ++FG PL+    Y  +E+ L++ ++ YW NF K GNPN      + E+ WP +      YL L T  N      G  S++C FW + L  L+ A    K
Sbjct:   69 DLHSLPKPESLNLNSNDDDMVIRTRKGKVRGITLTATTGKKVNAWMGIPYAQKPIGPLRFRHPRPAE--RWEGILNTTTPPNSCVQILDTVFGDFPGATMWNPNTPLSEDCLYVNVVTPRPRPTNAAVMVWIFGGGFYSGTATLDVYDHRTIVSEENVILVSMQYRLASLGFLYFGTG-DVPGNAGLFDQVLALQWVRDNVAAFGGNPENVTLFGESAGAVSVSLHLLSPLSRNLFNQAIMQSGSPTAPWAMISREESRVRGLRLAEAVGCPHEEYSISEAVECLRGKDPFDLVNNEWGTL--GICEFPFVPVIDGAFLDETPQRSLSNPSF-KRANILMGSNTEEGYYFIIYYLTELF---RIDGTEDVKVTREEFLRAVRELNPYVNQIARNAIVYEYTDWLRPDDPHRNRDALDKIVGDYHFTCNVNEFAARYAETGNTVYMYYYTHRSANNPWPSWTGVMHADEISYIFGEPLDPSRGYTREEIHLSKRIMRYWANFAKTGNPNMGDDGSWAETLWPEHSYSKREYLTLAT--NSSDIGYGPRSKQCAFWKKYLPQLLTATANMK 626          

Query:  259 FKSNDEMKLKTKRVLDLNDDDPELIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD---EIVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELD-EDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPN----PSVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            F+S++E+     R   LN +D  L+ +T++G +KG  ++     +V AW G+P+AQ P+G LRF  P  AE  S    LN    P SC+Q LDT    ++GA +WN    LSEDCLY+N+ AP+       V VWI GGG  +GSA+LD YD   +VS   V+ V++QYR+  LGF++ G  +++PGN G  DQ+ ALQW+++NI  FGGNP++VTL GES+GA S +MH++SP S  LF + I+QS +  APWA    EE+  R   L++ + CP D D   E++ CL  KD  +LV  E+      I  +PF P +DG F+ E+P+++L +     K  +++GSN  EGFY ++Y+  + F    +D  +D  +S + F   V  + P    F R  I +EY D +R       + ALD++ GD+ F C+V  FA   ++ GN VY Y++ HRS+ +PWP +TG  H DEI ++FG PL++ + YM +E+ L++ M+ YW NF K G+PN     S     WP +      YL L T  N      G  +++C FW + L  L+ A
Sbjct:   50 FRSSEELP----RPAALNSNDDPLVVQTRKGKVKGKTMTATTGKEVDAWFGIPYAQKPLGALRFRHPRPAERWS--GTLNATTLPNSCVQILDTVFGDFAGATMWNPNTPLSEDCLYVNVVAPRPRPTNAAVMVWIFGGGFYSGSATLDVYDHKTLVSEENVILVSMQYRVASLGFLYFGT-SDVPGNAGLFDQMMALQWVRDNIAAFGGNPDNVTLFGESAGAVSVSMHLLSPLSRHLFSQAIMQSGSPTAPWAIISREESIMRGIRLAEAVGCPHDRDNLQEVIDCLLIKDPIELVKNEW--GTLGICEFPFVPVIDGAFLDETPQRSLATSSFK-KANIMMGSNTEEGFYFIIYYLTELF---RIDMAEDVKVSREQFVSAVTELNPYVNQFGRHAIIYEYTDWLRPDDPHMNRDALDKIVGDYQFTCNVNEFAGRYADTGNTVYMYYYKHRSANNPWPRWTGVMHADEISYIFGEPLDSSKGYMPEEINLSKRMMRYWANFAKTGDPNVGDVESWTQTYWPPHTAAKKEYLTLDT--NSSEIGNGPRARQCTFWKKYLPQLLAA 602          

Query:  259 FKSNDEMKLKTKRVLDLNDDDPELIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD---EIVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELD-EDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPN----PSVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            F+S++E+     R   LN +D  L+ +T++G +KG  ++     +V AW G+P+AQ P+G LRF  P  AE  S    LN    P SC+Q LDT    ++GA +WN    LSEDCLY+N+ AP+       V VWI GGG  +GSA+LD YD   +VS   V+ V++QYR+  LGF++ G  +++PGN G  DQ+ ALQW+++NI  FGGNP++VTL GES+GA S +MH++SP S  LF + I+QS +  APWA    EE+  R   L++ + CP D D   E++ CL  KD  +LV  E+      I  +PF P +DG F+ E+P+++L +     K  +++GSN  EGFY ++Y+  + F    +D  +D  ++ + F   V  + P    F R  I +EY D +R       + ALD++ GD+ F C+V  FA   ++ GN VY Y++ HRS+ +PWP +TG  H DEI ++FG PL++ + YM +E+ L++ M+ YW NF K G+PN     S     WP +      YL L T  N      G  +++C FW + L  L+ A
Sbjct:   50 FRSSEELP----RPAALNSNDDPLVVQTRKGKVKGKTMTATTGKEVDAWFGIPYAQKPLGALRFRHPRPAERWS--GTLNATTLPNSCVQILDTVFGDFAGATMWNPNTPLSEDCLYVNVVAPRPRPTNAAVMVWIFGGGFYSGSATLDVYDHKTLVSEENVILVSMQYRVASLGFLYFGT-SDVPGNAGLFDQMMALQWVRDNIAAFGGNPDNVTLFGESAGAVSVSMHLLSPLSRHLFSQAIMQSGSPTAPWAIISREESIMRGIRLAEAVGCPHDRDNLQEVIDCLLIKDPIELVKNEW--GTLGICEFPFVPVIDGAFLDETPQRSLATSSFK-KANIMMGSNTEEGFYFIIYYLTELF---RIDMAEDVKVTREQFVSAVTELNPYVNQFGRHAIIYEYTDWLRPDDPHMNRDALDKIVGDYQFTCNVNEFAGRYADTGNTVYMYYYKHRSANNPWPRWTGVMHADEISYIFGEPLDSSKGYMPEEINLSKRMMRYWANFAKTGDPNVGDVESWTQTYWPPHTAAKKEYLTLDT--NSSEIGNGPRARQCTFWKKYLPQLLAA 602          

Query:  259 FKSNDEMKLKTKRVLDLNDDDPELIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD---EIVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGG-KGRFKALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPN---PSVFLES-WPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKALGVAKDVVS 820
            F+S +E+     R   LN +D  LI +T++G ++G  ++     +V AW G+P+AQ P+  LRF  P  AE  S  D+LN    P SC+Q LDT    ++GA +WN    LSEDCLY+N+  P+       V VWI GGG  +GSA+LD YD   +VS  +V+ V++QYR+  LGF++ G   ++PGN G  DQV AL+W+++NI  FGGNP++VTL GES+GA S +MH++SP S  LF++ I+QS +  APWA    EE+  R   L++ + CP D D   E++ CLR KD  +LV  E+      I  +PF P +DG F+ E+P+++L +     K  +++GSN  EGFY ++Y+  + F    +D  +  +S + F   V  + P    F R  I +EY D +R         ALD++ GD+ F C+V  FA   ++ GN VY Y++ HRS  +PWP +TG  H DEI ++FG PL+  + Y  +EV L++ M+ YW NF K G+PN     V+ ++ WP +      Y+ L T  N      G   ++C FW   L  L+ A    K+  S
Sbjct:   56 FRSGEELP----RPAALNSNDDPLIVQTRKGKVRGKTMTATTGKEVDAWFGIPYAQKPLESLRFRHPRPAERWS--DILNATTLPNSCVQILDTVFGEFAGATMWNPNTPLSEDCLYVNVVVPRPRPTNAAVMVWIFGGGFYSGSATLDVYDHKTLVSEEKVILVSMQYRVASLGFLYFGT-PDVPGNAGLFDQVMALEWVRDNIAAFGGNPDNVTLFGESAGAVSVSMHLLSPLSRHLFNQAIMQSGSPTAPWAIISREESIVRGIRLAEAVGCPHDRDNLQEVIDCLRVKDPIELVKNEW--GTLGICEFPFVPVIDGAFLDETPQRSLATSSF-KKANIMMGSNTEEGFYFIIYYLTELF---HIDGSEVKVSREQFISAVSELNPYVNQFGRRAIIYEYTDWLRPDDPHANRDALDKIVGDYQFTCNVNEFAGRYTDTGNTVYMYYYKHRSMNNPWPRWTGVMHADEISYVFGEPLDPSKGYTPEEVNLSKKMMRYWANFAKTGDPNVGDADVWTQAYWPPHTAAKKEYMTLDT--NSSEIGNGPRVRQCIFWKNYLPQLVAAKLEPKETCS 616          

Query:  259 FKSNDEMKLKTKRVLDLNDDDPE--------LIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDEI---VGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPS----VFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            F SN E      RV +L  D+P         LI +T++G +KG+ L+     +V AW G+P+AQ P+GDLRF  P   E S  D++LNT   P SC+Q +DT    + GA +WN   ++ EDCLY+NI +P+   K   V +W+ GGG  +G+A+LD YD   +VS   VV+V++QYR+  LGF+F  +  ++PGN G  DQ+ AL+W+++NI  FGGNP ++TL GESSGA S ++H++SP S  LF + ILQS+A  APWA    EE+  R   L++ + CPS   +I   + CLREK A +LV  E+      I  +PF P +DG F+ E P ++L       K  +LLGSN  EG+Y ++Y+  + FP +E    +  +S + +   V+ + P      R+ I  EY D I      + + ALD+M GD+ F C V  FA   +E GN VY Y++ HRS  +PWP +TG  H DEI ++FG PL   + Y  +EV  +  ++ YW NF ++GNP+ +    +  E WP +      YL+L  A N     +G   ++C FW + +  LM A
Sbjct:   91 FYSNHE------RVEELMADEPHYGPDEEDPLIIRTRKGRVKGITLTAATGKKVDAWFGIPYAQKPLGDLRFRHPRPIE-SWGDEILNTTTLPHSCVQIIDTVFGDFPGAVMWNPNTDMQEDCLYINIVSPRPRPKNAAVMLWVFGGGFYSGTATLDIYDPKILVSEENVVYVSMQYRVASLGFLFF-DTADVPGNAGLFDQIMALEWVKDNIAYFGGNPHNITLFGESSGAVSVSLHLLSPLSRNLFSQAILQSAAATAPWAIISREESILRGMRLAEAVHCPSSRTDIGPMIECLREKSADELVNNEWGTL--GICEFPFVPIIDGSFLDEMPRRSLAHQNF-KKTNILLGSNTEEGYYFILYYLTELFPKEE----NVGISREQYLQAVRELNPYVNDVARQAIVFEYTDWINPEDPVKNRNALDKMVGDYHFTCGVNEFAHRYAETGNNVYMYYYKHRSKNNPWPSWTGVMHADEINYVFGEPLNPGKNYSPEEVEFSRRLMKYWANFARSGNPSINAGGDMIKEPWPVHTVSGREYLSL--AVNSSSVGRGLRVKQCAFWQKYIPQLMAA 648          

Query:  278 DDPELIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPD---EIVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELD-EDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNP----SVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            +DP LI +T++G ++G  L+     +V AW G+P+AQ PVG LRF  P   E  S  DVLN    P SC+Q LDT    + GA +WN   EL+EDCLY+N+  P+       V VWI GGG  +GSA+LD YD   IVS   V+ V++QYR+  LGF++ G  +++PGN G  DQ+ ALQW+++NI  FGGNP++VTL GES+GA S +MH++SP S  LF++ I+QS +  APWA    EE+  R   L++ + CP D     E++ CL +KDA +LV  E+      I  +PF P +DG F+ E+P+++L +     K  +++GSN  EGFY ++Y+  + F    +D  +D  +S   F   +  + P      R  I +EY D +        + A+D++ GD+ F C+V  FA   ++ GN VY Y+F HRS+ +PWP +TG  H DEI ++FG PL+    Y A+EV L++ M+ YW NF K G+PN     S  L  WP++   +  YL L    N      G   ++C FW + L  L+ A
Sbjct:   75 NDP-LIVRTKKGFVRGKTLTATTGKEVDAWYGIPYAQKPVGSLRFRHPRPTEHWS--DVLNATALPNSCVQILDTVFGDFPGATMWNPNTELNEDCLYVNVVVPRPRPTNAAVMVWIFGGGFYSGSATLDVYDHKTIVSEENVILVSMQYRVASLGFLYFGT-SDVPGNAGLFDQMMALQWVRDNIAYFGGNPDNVTLFGESAGAVSVSMHLLSPLSRHLFNQAIMQSGSPTAPWAIISREESIVRGIRLAEAVGCPHDRSNLREVIDCLVKKDALELVKNEW--GTLGICEFPFVPVIDGSFLDETPQRSLATSSFK-KTNIMMGSNTEEGFYFIIYYLTELF---RIDGAEDVKVSRDQFISAISELNPYVNQIGRHAIIYEYTDWLHPDDPNLNRDAIDKIVGDYQFTCNVNEFAGRYADTGNNVYMYYFKHRSANNPWPRWTGVMHADEINYIFGEPLDPSRGYTAEEVQLSKRMMRYWANFAKTGDPNTGEIDSWMLAQWPQHTSVNKEYLTLDV--NNTEVGSGPRVRQCTFWKKYLPQLLTA 611          

Query:  277 DDDPELIKKTQEGSIKGVNLSP----QVRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDEI---VGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELDEDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNPNPS----VFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLMKA 811
            DD+  LI +T++G +KG+ L+     +V AW G+P+AQ P+GDLRF  P   E S  D++LNT   P SC+Q +DT    + GA +WN   ++ EDCLY+NI +P+   K   V +W+ GGG  +G+A+LD YD   +VS   VV+V++QYR+  LGF+F  +  ++PGN G  DQ+ AL+W+++NI  FGGNP ++TL GES+GA S ++H++SP S  LF + ILQS A  APWA    EE+  R   L++ + CPS   +I   + CLREK A +LV  E+      I  +PF P +DG F+ E P ++L       K  +LLGSN  EG+Y ++Y+  + FP +E    +  +S + +   V+ + P      R+ I  EY D I      + + ALD+M GD+ F C V  FA   +E GN VY Y++ HRS  +PWP +TG  H DEI ++FG PL   + Y  +EV  +  ++ YW NF ++GNP+ +    +  E WP +      YL+L  A N     +G   ++C FW + +  LM A
Sbjct:  111 DDEDPLIIRTRKGRVKGITLTAATGKKVDAWFGIPYAQKPLGDLRFRHPRPIE-SWGDEILNTTTLPHSCVQIIDTVFGDFPGAVMWNPNTDMQEDCLYINIVSPRPRPKNAAVMLWVFGGGFYSGTATLDIYDPKILVSEENVVYVSMQYRVASLGFLFF-DTADVPGNAGLFDQIMALEWVKDNIAYFGGNPHNITLFGESAGAVSVSLHLLSPLSRNLFSQAILQSGAATAPWAIISREESILRGMRLAEAVHCPSSRTDIGPMIECLREKSADELVNNEWGTL--GICEFPFVPIIDGSFLDEMPRRSLAHQNF-KKTNILLGSNTEEGYYFILYYLTELFPKEE----NVGISREQYLQAVRELNPYVNDVARQAIVFEYTDWINPEDPVKNRNALDKMVGDYHFTCGVNEFAHRYAETGNNVYMYYYKHRSKNNPWPSWTGVMHADEINYVFGEPLNPGKNYSPEEVEFSRRLMKYWANFARSGNPSINAGGDMIKEPWPVHTVSGREYLSL--AVNSSSVGRGLRVKQCAFWQKYIPQLMAA 648          

Query:  261 SNDEMK-------LKTKRVLDLNDDDPELIKKTQEGSIKGVNLSPQ----VRAWLGVPFAQAPVGDLRFAPPVDAEPSSEDDVLNTRRQPKSCMQNLDTT--GYSGADLWNTQEELSEDCLYLNIYAPKNATKALPVFVWIHGGGHSTGSASLDRYDGSQIVSGGEVVFVAIQYRLGVLGFMFLGEGTNIPGNMGFLDQVKALQWIQNNIGTFGGNPEDVTLVGESSGANSAAMHMISPKSEGLFHKVILQSSALNAPWAYAEPEEARERARNLSQLLDCPSDPDE---IVGCLREKDAKDLVAKEFDGAPSAINSYPFGPTLDGDFITESPEKALTSGLISSKIPVLLGSNANEGFYSLMYFDPDTFPDQELD-EDDQDLSEKDFNDVVQAIFPQFPFFVRELIKHEYRDLIRSGGKGRFK-ALDRMAGDFAFVCDVEGFAQDLSENGNQVYRYHFDHRSSQDPWPEYTGSKHGDEIEFMFGVPLETPELYMAKEVGLAEDMVTYWLNFVKAGNP----NPSVFLESWPRYQEPDWSYLNLTTAYNGGRAEKGTLSQRCKFWNELLNSLM 809
            S++EMK       L     L  N  D  LI +TQ+G ++G+ L+      V AW G+P+AQ P+G LRF  P  AE  S   VLN    P SC+Q LDT    ++GA +WN    LSEDCLY+N+  P+       V VWI GGG  +GSA+LD YD   +VS   ++ V++QYR+  LGF++ G   ++PGN G  DQ+ ALQW+++NI  FGGNP++VTL GES+GA S ++H++SP S  LF++ I+QS +  APWA    EE+  R   L++ + CP + D    ++ CL++ D  DLV  E+      I  +PF P +DG F+ E+P++++ +     K  +LLGSN  EGFY ++Y+  + F    +D  +D ++S ++F   V  + P      R+ I +EY D IR       + ALD++ GD+ F C+V  FA+  +  GN VY Y++ HRS+ +PWP++TG  H DEI ++FG PL+  + Y  +E+ L++ M+ YW NF K GNP    + S     WP +   +  YL L T  N     +G   ++C FW   L  L+
Sbjct:   43 SHEEMKNLRSFEELPRPEALGSNSADDPLIVQTQKGRVRGMTLTATTGKTVDAWFGIPYAQKPLGSLRFRHPRPAERWS--GVLNATSLPNSCVQILDTVFGDFAGATMWNPNTALSEDCLYVNVVTPRPRPTNAAVMVWIFGGGFYSGSATLDVYDHRTLVSEENIILVSMQYRVASLGFLYFGT-PDVPGNAGLFDQMLALQWVRDNIAAFGGNPDNVTLFGESAGAVSVSLHLLSPLSRHLFNQAIMQSGSPTAPWAIISREESIVRGLRLAEAVGCPHERDSLQAVIDCLQQSDPLDLVNNEWGTL--GICEFPFVPVIDGSFLDETPQRSMATASYK-KANILLGSNTEEGFYFIIYYLTELF---RIDGTEDVEVSREEFIRAVTELNPYVNQIARQAIIYEYTDWIRPNDPHVNRDALDKIVGDYQFTCNVNEFAEHYASTGNTVYMYYYKHRSANNPWPKWTGVMHADEISYIFGEPLDMSKKYTTEEIHLSKRMMKYWANFAKTGNPSMGDDGSWTKPIWPVHTASNKEYLTLDT--NTTEIGQGPRVKQCAFWKTYLPQLL 602