multidrug resistance-associated protein 1 isoform x3, snap_masked-scaffold1304_size49437-processed-gene-0.4 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000002221 (supercontig:LSalAtl2s:LSalAtl2s1420:21426:31801:1 gene:EMLSAG00000002221 transcript:EMLSAT00000002221 description:"maker-LSalAtl2s1420-augustus-gene-0.12") HSP 1 Score: 1122.46 bits (2902), Expect = 0.000e+0 Identity = 645/1556 (41.45%), Postives = 926/1556 (59.51%), Query Frame = 0
Query: 8 FC--RDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTW-TRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLAL-LQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLED----------KASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQ----------------WRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNV-IHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTS------------NPVTSEVETDELKVLATTTKEPPK-REVRVPS-----------------------EEVESPEETDNLIEET-----ADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWAD------------HNEAHPETGSD---RTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLI---YFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC RDPF+D D WNT DPN T C R T+LV +PC LF A L + IY+ + ++ R + + L+ F L+ V+L G+ GS + P +L + P + LA+ + V++ G ISP L F+L L I+ M++ T + + I+ F+ H +V+ P ED ++ D +S S + FSWLD LLW G K L + +L S++ V F ++ + K ++ V +P +S+ P L + G L A ++ + L FV P I+K +IK + E +W+G Y ++L SS + ++ + +++ ++++ SL+ +Y+K+LR+ ++ S GE+ N MSVDAQ+IV+ PY+ + +P I IA+Y L+ L + LAG++V + IP N F + K LQ Q++ KD R+KL+NE++ GIK++KLYAWE F+ I +R E+KI+ G L A +F + +P LV++ F ++ P +VL ++K FV + LFN++R PL P + V VS+KRIN+F+N+ EID V TA AI + +A L W+SD+ + ILS ++L I GSL A+VGTVG+GKSSLLS+ LGEM+K+SG + VRGSIAY QQAW+ N +L++NILF++ + YT+++ C L+ DL +L D TEIGE GINLSGGQKQRVSLARAVYS +DIYLLDDPLSAVD+HVGK I+ V+ S+ G LKDKTRV+VTH V +L D IIV+K+G+V+E G+Y++LL AF+EF++Q+ S + + +EL T K+ + R V + S +E E TDN ++T ++EK G V +Y YV+++ + + ++ L+N L+ W+D N E D +YL +YGG + Q I+ + ++C +A++ +H+++L+ +++SPM+FFDT P GRI+NR D+D +D V+P L I C LS ++VV +TP+F IIP LI YFF+QR +V S+Q+KR ES ++S I + FSET++G A+IRAY Q F+ ES+++V F +NRWL +R+EV+GNL+VF AA+ AVL R++LSPG+ GLS++YAL + +LNW++RM E+ETN VA+ERI EYT E EA W + D K WP +G +SFK+Y+TRYR GLD VLK + +++ EKIGI GRTGAGKSS TLS+FRIIE V G I+IDG DI +LGLH LRSRITIIPQDPVLF+G+LR NLDP + +++ I A+ H+HLK I LK GL + +SEGGEN S+GQRQLICLARALLR+T++L+LDEATAAVDL TD+LIQ TIR EF+ TVITIAHRLNTI+D +I V +G+ E+G+ AELLA+ S +M +DAGL
Sbjct: 20 FCSDRDPFWDPDYAWNTNDPNFTSCFRKTILVWIPC-LFFWAFLPFHIYKLYHSKARKVPLKTLGRVKALSCFILILIAFVDL--------GY-WGSKEFYPKDLIN-PIIRAITFLAVFILLFVERARGYRISPLLTSFFLIYFATNTIDLYGHIRWVMMSGTTXLADITFFLHFFCIIVSFLCHFFVEPRP-LYEDTAVNDIKSNNPCPLITSSFPSQISFSWLDSLLWTGFKRNLSFDDLWDLVPSLSSRTVVPIFLQRLDSALRRVKTNENGITYAKGDDNVEVKTKHEKKPQLSILPALARTFGPSILSAAVIKIVSDSLNFVPPLILKRIIKFSTNQEELWKGILYAVILFASSTVGSLVLSKFFYKMYVVGMKIKTSLISTIYRKALRVPTSTKKNISTGEIVNLMSVDAQKIVDLMPYINTVWSAPFQITIAIYLLWQTLGPSVLAGVLVMILLIPFNGFIASRTKTLQTNQMKEKDERIKLLNEVVQGIKIVKLYAWEQSFLDIISNVRSKEVKILTHIGYLQAGNSFIWTCAPFLVSLVTFATFILSSPENVLDSEKAFVCLTLFNILRFPLSMLPMIIGSMVLAGVSIKRINKFMNSEEIDEEAVEKKTAYPDDKFAINLEKACLKWESDEDKN-ILSDVSLDIEVGSLVAVVGTVGSGKSSLLSAILGEMDKVSGLITVRGSIAYGAQQAWVLNTSLKNNILFNKSYDGDKYTRIVEACALKSDLDMLPGGDETEIGEKGINLSGGQKQRVSLARAVYSGSDIYLLDDPLSAVDSHVGKHIYDNVISSSSGILKDKTRVMVTHGVTYLPFTDKIIVMKDGRVSEIGTYKELLRQKGAFAEFIVQFLSEANENEVNENIKHDIEESFGKNELLEQITKAKQIVRERSVSLNSGDLVTSLVKNNPTNSASGSTTSLKENSGDESTDNDTKQTRPTTSQTQQYQDEKVETGSVKWNIYMHYVKNMSIILVVACSSCFVIYQALNTLSNVLLAWWSDAVMKIEVRTGLNDNRTLDEINQDIMDXQVYYLSIYGGYCLGQGIVVVMGFVFMYLACMEAAQRLHNQMLESILKSPMSFFDTTPQGRILNRLGKDLDVLDSVMPMVLRGWISCFLGVLSSLIVVMVTTPVF---IIPASLIIICYFFIQRIYVATSRQLKRLESSSRSPIXSFFSETVSGAATIRAYGQSSTFISESESKVDDNQKANFPATVSNRWLAVRLEVVGNLIVFTAALLAVLGRDSLSPGLVGLSVSYALAVTASLNWLVRMASEVETNIVAVERIQEYTKAEKEAPWIIE-DTKPDEDWPRKGEISFKNYSTRYREGLDYVLKNVSLDIEGGEKIGIVGRTGAGKSSFTLSMFRIIEPVTGNIIIDGVDITKLGLHQLRSRITIIPQDPVLFSGSLRRNLDPLDEYNETNIMEAISHSHLKPFIDSLKDGLEYHVSEGGENLSLGQRQLICLARALLRRTRVLILDEATAAVDLETDNLIQKTIRSEFKDSTVITIAHRLNTIMDYSKILVLKNGERVEYGTVAELLADKKSQFYSMCSDAGL 1558
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000008248 (supercontig:LSalAtl2s:LSalAtl2s498:229862:245360:1 gene:EMLSAG00000008248 transcript:EMLSAT00000008248 description:"maker-LSalAtl2s498-snap-gene-2.25") HSP 1 Score: 1039.25 bits (2686), Expect = 0.000e+0 Identity = 611/1529 (39.96%), Postives = 890/1529 (58.21%), Query Frame = 0
Query: 3 VGQRPFCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPC-ILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLL-----GQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQS-----RMVASGTVEEWVLLITYVPIILGLFIAHCWVD----IDPRAAEDLSLED--KASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKA--FTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLL-ADGKAFSEFLIQYTSNPVTSEVETDE-----LKVLATTTKEPPKREVRVPSEE---------------------------VESPEETDNLIEETADDL----IEEEKTVAGRVGAKVYWTYVQSIGT-SQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP-LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAG 1472
+G FC DP ++ +L W T DP T C T+LV VP ILFL+ Y+ WT SS+ +L F+ ILV L +F + + D ++ + + L F+ + +LQ + + G S PLF+FWL E+ ++ R+ + V ++I Y P+++ L W D + DL+ AS S L FSW D +++ WK + D K+ W ++ E ++ +P LWP L ++ L + + F + F +PQ++ L+I + D EP+W+G+ Y + + ++T+ + + +I+ +++R SL +++ K++ L + +++ SVGE TN M++D+QR+++ Y+ + SPL I+IAMY L+ L ASLAGL V + IPIN+ K VKK Q+Q KD R+KLM+++L GIKVLKLYAWE F+ + R+ EI +K + A +F + S+P LV + F YV +D ++LT FV++ LFNL+R PL P ++++++ VSL RIN FLN ++D + H + HA++M +L+W++D+G++ L ++L I GSL AIVG VG+GKSSLLS LGEME + G + V G Y PQQ W+QN TLR+NILF + F+ Y +VI C L PDL +L D TEIGE GINLSGGQK RVSLAR ++ DIY+LDDPLSAVD HVG+ +F V+ S G LK+KTR+ VTH FL + D IIV+KNG ++ESG+Y+ L+ + F++FLI Y + + ++ D+ +K L +T + E R+ + + + S + D+L E ++DL IEEEK +G + +Y Y + G + FF ++F + AN WLS+W+ A T YL +Y +G Q I + + AS IH KLL+ V+R+P++FFDTNP GRI+NRFS DID +P + +I +F+ L IV++C + P F +I+P + Y +Q+F++ ++Q+KR ES+++S I++HF+ET+TG+ +IRA+ F+ E+ ++ C F V ++RWL +R+E LGN++V F A+F++ SR PG+ GLS++YAL + LN +I + ++ETN V++ERI EY + EA +DLP DP WP G + F +Y TRYR GLDLVLKGI+ ++ EKIGI GRTGAGKSSLTL+LFRIIE +G I IDG++I LGL LRSRITIIPQDP+LF+G+LR NLDP E +D +IW AL+++HLK + +L GL + EGG N SVGQRQLICLARA+LRKT+ILVLDEATAA+DL TDDLIQSTIR EF+ TV+TIAHR+NTI+D +RI V G IAEF P LLANP S ++ ND+
Sbjct: 21 MGTSTFCSDPLWNSNLTWYTEDPYFTDCFISTVLVYVPSGILFLLTP-----YEIWTCFNLGENSSRISRTWL---NFSRTILVGFLILLSLVEFIF---ELLREDNVLSNIVAPGIYFLTFLNVFILQI-LGRIKGRVSSGPLFVFWL----LEVFAAGFSFRNWRNIHRVPNTDLVTLSTIVIQY-PVVVILLFMGFWADGNNNYNKIGDNDLNPSSLRMASFTSKLTFSWFDPFIYKA------WKKXVTDDDLYEINDEFKSCGVLPSWDREMEKEIRRKHLKNKPINILWP-LVRSFKSTLLASSALQFFYSVFQFGAPQLVDLIINFVSDPKEPIWKGYLYLFAICSITFINTLIYSQSNYYSYITGLKIRTSLTSSIFNKAVNLKSSSKKQMSVGETTNLMAIDSQRLMDFCLYIDMIWSSPLKIIIAMYLLWQVLGPASLAGLAVMILLIPINIVVGKKVKKFTAIQMQNKDKRIKLMDDILNGIKVLKLYAWEPSFIDAVTNFRVQEIGALKKSALINAVTSFMWTSAPFLVALASFTTYVLIDEKNILTPSTAFVSLTLFNLLRLPLNLLPMMIMKAIQSKVSLDRINLFLNKEDLDLLAISHESQ--GSHAVKMCNVSLSWETDEGLNT-LEDIDLDIEKGSLVAIVGQVGSGKSSLLSGILGEMEIVRGSINVDGQTIYAPQQPWLQNETLRNNILFGKRFNKKLYRRVIDACALSPDLDMLPAGDLTEIGERGINLSGGQKARVSLARCTXNNGDIYILDDPLSAVDVHVGRHLFENVISSQTGLLKNKTRIFVTHGAIFLPQTDKIIVMKNGVISESGTYRDLIEKENGEFAQFLINYLVDEKENILKNDQDLKTIIKDLESTVGGSEELEKRLEAAQSDKSTALTDLIQGTKYLDENTSDQCSSIASRKGEDDLDEVVSNDLNERLIEEEKIESGGIKLNIYLNYFKRTGLLASFFGILFYFSYQGFSLG-ANLWLSKWSTDRAAINSTSI--RNHYLEIYAILGFFQSIFTMLGSVTIAIGTLNASMKIHGKLLENVLRAPLSFFDTNPLGRILNRFSKDIDVAXTTLPFNIRMMIAQSFNVLGTIVIICIALPWFFVIILPAVICYALIQKFYISCARQVKRIESISRSPIYSHFAETLTGIPTIRAFGMVHHFIDENVNKIDFNAKCYFPTVISSRWLAVRLETLGNILVIFVALFSITSRGTTDPGMVGLSLSYALSVTTILNMLITVSTDVETNMVSVERIKEYENIPQEAPYDLPNSDPP--PNWPEHGVIKFDNYKTRYRKGLDLVLKGINCTIQKGEKIGIVGRTGAGKSSLTLALFRIIEPSEGSIYIDGENIRFLGLGKLRSRITIIPQDPILFSGSLRMNLDPFEAFADRDIWIALEYSHLKSFVWNLGDGLNFSVLEGGRNLSVGQRQLICLARAILRKTQILVLDEATAAIDLETDDLIQSTIRSEFKDSTVLTIAHRINTIMDSNRIMVLDAGTIAEFDDPQNLLANPDSMFYSLVNDSN 1517
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000003611 (supercontig:LSalAtl2s:LSalAtl2s197:49356:53594:-1 gene:EMLSAG00000003611 transcript:EMLSAT00000003611 description:"augustus_masked-LSalAtl2s197-processed-gene-0.4") HSP 1 Score: 990.719 bits (2560), Expect = 0.000e+0 Identity = 530/1275 (41.57%), Postives = 774/1275 (60.71%), Query Frame = 0
Query: 208 ASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDS----NEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPH-----AIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
AS SLL + W+ LLW+G K P+ +L + + + + + + K K+ P L K G+ +I + F +L V PQI+KL+I H DS E W+G+ Y +L+ S L ++ Y + + + ++++R SL +Y+K L+LSN +R+ SVGE+ N MSVD RI + P++ L SP I++++ F++ EL A + G + I IP+N S KK Q++Q++AKD R K++NE+L GI++LKLYAWE ++ +I IR EI I+K L +F+ F + S+P +V + F +V +D ++LTA+K FV + N M+ P+ FPF ++ ++ VSLKRIN+ L + E+ V ++ AI + + W ++D + LS +NL I GSLTAIVGTVG+GKSSL+S+ LGEM K SG+V+++G IAYVPQ++W+QN +L++NILF + + Y +V+ C L DL++L D TEIGE GINLSGGQ+QR+SLARA+YSDAD+Y+ D+PLSA+D+ VGK++F VL++ G +KDKTR+LVTH +++L + +I V+ G++ G+YQ+LL + + E PK + + T N +E+ A +I++E GRV VY Y+QSIG F ++F L + ++ WL W + + R YLGVYG +G+ Q + F L M +ASKVIH++ +MR+P++FFD+ P GRI+NRFS DI D ++ + + + C F L +++++ S P+F +P L++ +Q +V S+Q+KR +SVT+S I++HFSE++ GL+SIRAY Q +F+ ES ++ C + ++ ANRWL +R+E +GNL +F AI + + E + PG GL I+YAL + LNW+ R E+ETN VA+ER+ EY + E EW L D + WP++G V FK+Y+ RY+ DLVLK I+ + E++GI GRTGAGKSSL+++LFRI+EA G+ILIDG+DI+ LGLH LR +T+IPQ+P+LF+G LR NLDP SD +IW+ L HLK +I DLK GL H ISEGG N S GQRQL+CLARALLR KIL+LDEATAAVD TD+ IQ TIR F CT++TIAHRL TI+D D+I V G + EFGSP EL N S +M N AG+
Sbjct: 160 ASFFSLLFYEWITPLLWKGFKKPITEDDLWNLNKDLTCGETSRRLDQYYFKSGNKKI---GIP----------LMKAFGFEFVIGSTIKFFSDILSMVLPQIMKLMINHADSEFEMKERSWKGYLYPSMLIIVSFLQSVLLAKYFEIVFLVSMRIRASLTSLVYRKCLKLSNSSRKNKSVGEIVNIMSVDVSRIADLMPFLTLLWSSPFQIVVSVIFMYNELGWAIIGGTGILLITIPVNAILSYFGKKFQMKQMKAKDNRTKILNEVLGGIRILKLYAWEPSYINKIEGIRGVEIGILKKAAWLTSFMGFIWSSTPFIVALASFATFVMVDDRNILTAEKAFVTQSYINKMKMPMAXFPFVIVXAISATVSLKRINQLLTSDELQKDAVERVPMKINQKIDQGDAIVIRDGNFKWSTEDS-ENTLSNINLRIKHGSLTAIVGTVGSGKSSLISAILGEMVKKSGKVRIKGQIAYVPQESWMQNTSLKNNILFGKPYDEEWYNQVLEYCCLTYDLSLLPAGDETEIGERGINLSGGQRQRISLARAIYSDADVYIFDNPLSALDSQVGKSVFNNVLNNNTGIIKDKTRLLVTHGISYLPHVHHIAVMLKGEIIHEGTYQELLEKKIIQTIEEEEEQEKDGVQENN-------INNYNNIPK-----------TFDATVNNLEKAA--IIQKEGLETGRVSWSVYKYYIQSIGFLGAFLIIFNQMLNQLFGFGSSIWLEAWTQEDYGNATIPKYRD-LYLGVYGALGIGQAVTIFLLSLSVAMFTLKASKVIHNQTYDRIMRAPISFFDSTPQGRILNRFSKDISICDNILGSNIRQWLXCLFXFLGIVILIVSVLPLFLLFALPTSLVFILIQNIYVASSRQLKRLQSVTRSPIYSHFSESLNGLSSIRAYGAQSKFILESINKIDTNQRCNYPSIIANRWLAMRLETIGNLCIFGXAILTMTNPELVGPGKVGLVISYALILTQNLNWLXRQTSEIETNIVAVERLKEYAGLDIEKEWRLHKD--TSYNWPSQGKVEFKNYSLRYKANSDLVLKKINFTIFGGERVGIVGRTGAGKSSLSVALFRIVEAANGQILIDGKDISTLGLHDLRESLTVIPQEPLLFSGTLRSNLDPENAFSDHDIWNTLGSVHLKEYIRDLKDGLNHSISEGGLNLSSGQRQLMCLARALLRSCKILILDEATAAVDWETDEKIQETIRCYFPSCTILTIAHRLKTIIDYDKILVLDKGTVIEFGSPNELYMNSDSVFHSMINAAGI 1397
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000011700 (supercontig:LSalAtl2s:LSalAtl2s812:79332:86643:-1 gene:EMLSAG00000011700 transcript:EMLSAT00000011700 description:"maker-LSalAtl2s812-augustus-gene-0.6") HSP 1 Score: 922.154 bits (2382), Expect = 0.000e+0 Identity = 503/1322 (38.05%), Postives = 797/1322 (60.29%), Query Frame = 0
Query: 169 VEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCL-----------SLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRK-QAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNE-PVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDP-THVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEM---EKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
+EE + I +V ++L +AH W + PR +E + L C S + FSW+ L+W+G K P+K K+L S+N F K W K + K ++ + P S++P L +++ L L LL SP +++ LI S + P+ QG +++L + +L T Y ++ ++++ S+ +Y+K+LR+ + R + GE+ N MSVD Q+IV+ P + + PL I+ A+Y L L ++LAG++V + IPIN F + +K Q++Q++ KD R+K MNE+L GIK++KLYAWE F + I IR EIK++K+ + + F+ + S+ +++ F +YV DP H+L ++KIFV+I+LFN++R PL + VSLKRIN+FL + E++ ++ +N AI + ++ + + +++ + G+L AI+G VG+GKSSL+S+ LGEM K + V++ GS+AY PQ AW+QN++++DNILF ++F+ Y +V++ C LE D+ D TEIGE GINLSGGQKQR+SLARAVYS +DIY LDDPL+ VD+HV K +F +V+ S G L+ KTR+LVTHN++FL +D I LK+G++ E G+Y++L+ FSE + + +N +T++ +D KV+ +E K+ + ET + +EE G+VG +VYW ++ IG + ++ ++ ++ WLS W+D + +D ++LG+Y G+GV + + + L+ +S AS+++H L Q ++++PM+FFDT P GRI+NRF DI+ +D + + + F ++ + ++ + PIF + + ++YF + + S+Q+KR SV S I++HF ET++G+ ++RAY + F E + R+ + F + A+RWLG+R+ ++GN ++F +A+F+VLSR+ ++PG GL+++ +L I L+W+IRM +LE N VA+ERI EY++ ESEA W+L D K+ +WP +G ++ K+ + +YR LD VL+ I++ + +KIGI GRTG+GKS+L L+LFR++E G+I IDG DI ++GLHTLRS++TIIPQDP LF+G LR NLDP + D E+ +L HA+L+ + + GL I+E GEN S+GQRQLICLARALLRK K+L++DEATAAVD TD LIQ I+ F TV+TIAHRL T+LD +I V G I E+ SP LL++ +S M ++G+
Sbjct: 700 LEELMSSIIHVTLLLLNVLAHFWPEPPPRYSEYVRLVGVEGCHNPSPDTQCGYPSYIFFSWMSSLMWKGFKRPIKQKDLWDFIPSVNTALVNPHFLKHWNKIYTQTKFSNYPTSKSP--SIFPALLRSYWPLLLKGAFAKLLHDLLLICSPMLLQYLILFSYSPDIPLGQGIALSVILFGNKILGTFFIARYFFYMVTVGMKLKTSITSLIYRKALRI-HSTRDDTTSGEIVNLMSVDVQKIVDLMPLLNTIWSGPLQIIAAIYLLINTLGYSALAGVLVMFLLIPINGFIAVRMKNAQMKQMKKKDERVKKMNEILQGIKIIKLYAWESSFSKLISSIRFEEIKLLKLSSKYFGFMMLTISSTTFFISLFTFIVYVVSDPENHILDSEKIFVSISLFNILRFPLNMLTHVIGGIASASVSLKRINKFLASEELEE-GILVRSNSHDHQAI-CIHPSSSFSWKGSSESLFKDISMDVNRGNLIAIIGPVGSGKSSLISALLGEMLFTSKGTNPVEIHGSVAYTPQNAWMQNVSVKDNILFGRKFNKNWYDEVLKACSLESDMEXFPSGDSTEIGEKGINLSGGQKQRISLARAVYSQSDIYFLDDPLAXVDSHVAKHLFEEVIGSN-GLLRGKTRILVTHNLSFLHLVDEIYFLKDGEITEKGTYKELMEKNCDFSELISNHANNKITNQ--SDSEKVMEKINEEGTKQPI------------------ETNFKIYDEETLHTGQVGIRVYWYFLSKIGMLAGILAFSFFIISQILATGSSVWLSVWSD-----AKNNTD-IYYHLGIYAGLGVSNIFISTAGTLILSLSLLDASRILHGTLFQCIIKTPMSFFDTTPLGRILNRFGQDIEVLDTKMSFCIFGSMTGTFAYIATVTIISINVPIFIIPTLAIFVVYFVILIVSLSSSRQLKRLSSVATSPIYSHFGETLSGINTVRAYSLEKAFYSEFERRLDEYQKRNFPVIMADRWLGIRINLIGNFIIFASALFSVLSRDTITPGQLGLNVSSSLAITSILSWVIRMYSDLENNIVAVERIKEYSNKESEAPWELEEDLKLNSSWPLKGEITIKNLSLKYRKDLDWVLRDINVHISPGDKIGIVGRTGSGKSTLALALFRLLEVNSGQITIDGVDIKKMGLHTLRSKLTIIPQDPTLFSGTLRLNLDPFGLFKDMELIESLKHAYLQDFLKE--DGLDKVIAENGENISLGQRQLICLARALLRKNKVLIMDEATAAVDSETDKLIQKAIKDNFRDSTVLTIAHRLQTVLDYSKIIVIDSGCIIEYDSPKNLLSDSSSTFYKMCLNSGI 1987
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000001655 (supercontig:LSalAtl2s:LSalAtl2s128:1836948:1854487:1 gene:EMLSAG00000001655 transcript:EMLSAT00000001655 description:"augustus_masked-LSalAtl2s128-processed-gene-18.4") HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0 Identity = 403/1179 (34.18%), Postives = 634/1179 (53.77%), Query Frame = 0
Query: 304 FVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHA----------IEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVR---GSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDL-KLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAM 1467
F P ++ L+K M D + G+FY L S+ L + + ++ +++R S++ +LY+++L +S YS GE+ N+MS+D R+V P P +++ +Y L ++ V+S G+ + IPIN + + L + AKD R+K++ E++ GI+V+K Y WE F + R EI +K L A + + S+P+++++ F Y A+ + LTA K+F ++ALF ++ P +FPF + ++ VS+KR+ FL+ I+ D + A I++ EA+ + D L +++SI ++G VG+GK++ L++ LGE+EK SG++ VR IAYV Q WIQN ++RDNILF + + YTKVI+ C L+ D L D T GE G LSGGQK R++LARA+Y D DIYL+DD S++D +VG ++T+V+ LK KTR+L THN +++ + +I +K+G E + + +T P S + + DN DD +EEE G V ++Y Y Q+IGT T++ L V + WLS W + T + T Y+ VY G+ V IL R L A+K+IHD LL ++R+ + FFD+ P GRI+NRFSSD +D +P L+ + F ++V + P V++PLGL Y+ +Q + S+ +KR SV+ S I+ HF+ET+ GL IRA + RFL E++ V+ + SA+ WL +R++++G++VVF A+ +V++ E++ G+ GL+++YALG+ L ++ E E VA+ER +Y E + L+ + + WP +G V FK RY++ L VL ++ + + EKIGI GRTGAGKSSL +LFR+ G I++DG I L L R + +IPQDP +F+G +R NLDP HSD E+W ++ ++L I GL I +GG++ S+GQ+QL+CLARA++ K++ +DEATA+VD TD LI++ ++ F TVITIAHR+ T+L+ DRI V S+GQI E G P +L+ +P S + +
Sbjct: 324 FFCPLLLNRLVKFMEDPKADLRWGYFYAFSLFVSTFLVAICNTQFNFKMNELGLKVRASVIQSLYKQTLSVSEANLNKYSRGEIINFMSIDVDRVVNFAPSFHAFWSLPFQMVVTLYLLHQQVGVSSFVGVGFAILMIPINKVIATKIGSLSGHMMSAKDDRVKIIAEIIEGIRVIKYYCWESFFTDKTNSHRNNEIYYLKWRKYLDAVCVYLWASTPVIISVSTFATYSALG--NPLTAAKVFTSMALFAMLSGPFNAFPFVINGLIEANVSIKRLARFLSLPSINRIKYFTEYKDENTKASKEIETKIPDIQIMEASFGFTKDCFT---LRNIDVSIKRQEFVGVLGPVGSGKTTFLNAILGELEKQSGKISVRDPLSGIAYVQQVPWIQNKSIRDNILFGEMYIHGKYTKVIKACCLDHDFKHLHRGDHTIAGEKGAALSGGQKARIALARAIYQDKDIYLIDDVFSSLDVNVGYKVYTEVM---LNLLKRKTRILCTHNPQYINDANIVIKIKDG-------------------------------------EFESVKQSTHLVPTSTSPDFSYDTSMFDFKDN--SNVIDDSVEEEMQETGVVAYRIYKKYWQAIGTYLAPTILISIFLMQVASNTTDLWLSHWVSTDNFQNNT--EDTDHYIYVYSGLAVFHTILTLIRAFLFAYGGIHAAKIIHDLLLGVLLRAKIYFFDSTPAGRILNRFSSDTYAIDDSLPFILNIFLSQIFGVFGRVLVCVYAVPWILIVLLPLGLFYYEIQCKYRPGSRDLKRISSVSLSPIYEHFNETVHGLKIIRASKASQRFLLENEELVECNQKARYAAFSASLWLEIRLQLIGSIVVFSIALISVINFESVDAGLVGLAVSYALGMTXRLAEVVVSFTETEKELVAVERAYDYIDRIYEESYSGVLN--MPYNWPNQGVVEFKDIRLRYKDHLPYVLNKVNFKTKPKEKIGIVGRTGAGKSSLIAALFRLSSFSHGEIMVDGIRIRLLPLIDFRRQFAVIPQDPFIFSGTIRQNLDPYAQHSDQELWDSIKLSYLYNIIYSFGSSGLDTLIGDGGKSLSIGQKQLLCLARAIITSAKVVFIDEATASVDKETDRLIRNVLKTAFNDKTVITIAHRIETVLNSDRIFVMSNGQIIEEGKPEDLIKSPNSEFRKL 1451
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000752 (supercontig:LSalAtl2s:LSalAtl2s111:55855:93761:1 gene:EMLSAG00000000752 transcript:EMLSAT00000000752 description:"maker-LSalAtl2s111-augustus-gene-1.10") HSP 1 Score: 595.119 bits (1533), Expect = 0.000e+0 Identity = 400/1319 (30.33%), Postives = 657/1319 (49.81%), Query Frame = 0
Query: 210 CLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFR-VLLPFVSPQIIKLLIKHMDSNEPVW---QGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSF-PFTLIESVKVFVSLKRINEFLNASEI----DSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLAT------TTKEPPKREVR---------VPSEEVESPEETDNLIEETADD---LIEEEKTVAGRVGAKVYWTY-VQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLH-------------------------IMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTH--NESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAG 1472
C +++ W + +G K +L K+ R + K+W+K+ K+ F+ P S + + L++ LF +L P I +I + S + +F++ +L+ + ++ + Y + +Q+R + +Y+K+L LS + S+G+M N +S D R + ++ L ++P+ + M + ++AG + FI + K KL++ D R+++MNE+L GIKV+K+YAWE PF++ + R + + P+ + + +FG+ + A KIF+ LF+ ++ PL F P + S + VS+KRI EFL +E+ N + P +E+T+ + W D + L ++ S+ G L AI+G VG GKS+++ S LGE G++ ++G I+Y Q+AWI + ++R NIL + Y +VIR C LE D+ D T +GE GI+LSGGQK R++LAR VY+ ADIY+LDDPLSAVD HVG+ +F + + L DKT +LVTH + FL +NII+L +G++ SG+Y+KL++ F +L + TS S++ +D L + + + K+ K+ VR VP + E D EE + +E + G V +Y Y V G +F V FL + + ++++WL W + +A + G FY Y + +Q+ DF + + MSC ++S+ +HD++ + V + FFD NP GRI+NRFS DI D+++P L + +++ + P+ I+ L LI ++++++ S+ +KR E +T+S +F+ + ++ GL +IR+ + ++ + E T+ + + NR+ +++ +L + + + G GLS+T +L + + W +R E+E ++ER+ EY E + D+ LDP +WP +G + F + +Y VLKG + +G+I IDG +I +L L +R +I+IIPQDP+LF G +R NLDP + + + IW AL+ A L +S+L+ GL E+SEGG NFSVGQRQL CLARA+LRK K+L++DEATA VD +TD LIQ IR EF+ CTV TIAHRL T++D DRI V S G+I E G+P +LL++P++ M N G
Sbjct: 341 CKAIIFIKWTIPFIRKGQKEDFDVHDLYKTLREDYSRELNDRLEKEWQKELS-KVKTFSGNYHP--SFAKAAIRTFRLQTLLSGXFVLFEECVLRIAQPFAIFKIIGYFSSGGTXMSEXELYFWSGILVGAGVIFVLFDQRYWYLSLKTGMQLRIAASAIIYRKALTLSKASLGRSSIGQMVNLLSNDVNRFDNSTVFLQYLWVAPIQFICVMLITSYFAGIEAVAGGALLIFFIFFQTYMGKMFSKLRLMTASKTDIRIQIMNEILDGIKVIKMYAWETPFVQLVTNARNRFVLL------------------PVFLLMVLFGVEI--------NAQKIFLIFGLFDAIKLPLTHFFPSAISASSEALVSMKRIEEFLLLNELRDVQSKINHVILPGRYEPLTVEVTKISGKW-LDSSNEFTLKNISFSVEIGELCAIIGPVGCGKSTIIQSLLGEFPVSYGEINIKGRISYASQEAWIFSGSVRQNILMGKPLIDKRYREVIRVCALEHDVREWPDGDYTFVGEKGISLSGGQKSRINLARCVYASADIYILDDPLSAVDPHVGQQLFDTCI---QKFLSDKTVILVTHQLQFLKNANNIILLNSDGEIEASGTYEKLMSQS-GFVTYL-EATSEEEDSDLLSDVLSDVKSDGEYMRSQKKKLKKGVRSRRSSTSLLVPVPYIGGSTERDTFPEEKGSQEWKMGSKETIIEGSVSLSLYHKYFVAGGGFFKFLCVYFLSLITHTLFVVSDWWLRLWTNAADAR-KLGPLPPTFYFSEYQDM-TLQITADFQVDFFNFIYCSIYLSLIIILLFSAQLSVRQLFMSCMRSSQTLHDRMFEKVAFTNSRFFDLNPNGRILNRFSKDIGSXDELLPPAL-------LSGSGIFILISMTNPLIVVGIVVLLLILLTIRKYYLNASRAVKRLEGITRSPVFSQLASSLDGLTTIRSMKIEEMLIEEFDYLQDIHTSSYYSFLVVNRFFAFCGDLMLSLFTASMVSMFLFYNRDATGGDVGLSLTLSLALCGMIQWGLRQSAEVENFMTSVERVAEYGDLPKEKGLKGDIKLDP----SWPDKGVIEFSNVNLKYDGTTPYVLKG-------------------------------LTEPEGKIFIDGVNICRLSLQDVRKKISIIPQDPLLFKGTIRKNLDPFDEYGELAIWHALEQAKLSVAVSELEGGLETEVSEGGNNFSVGQRQLFCLARAILRKNKVLIMDEATANVDPMTDSLIQEAIRTEFKDCTVFTIAHRLYTVMDSDRILVMSDGEIKELGAPLDLLSDPSNIFYQMVNQLG 1580 HSP 2 Score: 231.106 bits (588), Expect = 2.030e-61 Identity = 126/285 (44.21%), Postives = 170/285 (59.65%), Query Frame = 0
Query: 1185 LNWMIRMLCELETNSVALERILEYTH--NESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAM 1467
+ W +R E+E ++ER++EY E E D+ LDP +WP +G V F + + RY VLKG++ + S EKIGI GRTGAGKSS+ +LFR+ E +G I IDG DI ++GL +R +I+IIPQDP+LF G++R NLDP +D +IW+AL+ A L + DL GL + E G NFSVGQRQL CLA A+LR+ K+L++DEATA VD TD LIQ IR+EF+ CT EFG+P +LL +P + L M
Sbjct: 2 IQWGLRQSAEVENFMTSVERVVEYGELPKEKGLESDIKLDP----SWPDKGVVEFSNVSMRYSQHQPNVLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEP-EGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCT--------------------------EFGTPKDLLKDPNNLLSRM 255 HSP 3 Score: 53.9138 bits (128), Expect = 3.366e-7 Identity = 52/194 (26.80%), Postives = 85/194 (43.81%), Query Frame = 0
Query: 623 ILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSF--LGEMEK----------LSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAV----DAHVGKAIFTQVLDSTE-GCLKDKTRVLVTHNVNFLDKM 799
+L +N I+G GAGKSS++S+ L E E G + +R I+ +PQ + N ++R N+ EF+ + +L + L H + + E G N S GQ+Q LA A+ + ++D+ + V D+ + +AI + D TE G KD L+ N L +M
Sbjct: 66 VLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEPEGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCTEFGTPKD----LLKDPNNLLSRM 255
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000090 (supercontig:LSalAtl2s:LSalAtl2s1014:9799:23913:-1 gene:EMLSAG00000000090 transcript:EMLSAT00000000090 description:"maker-LSalAtl2s1014-snap-gene-0.6") HSP 1 Score: 418.698 bits (1075), Expect = 5.973e-128 Identity = 294/952 (30.88%), Postives = 471/952 (49.47%), Query Frame = 0
Query: 555 MRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSP-------HAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEM-EKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTK----EPPKREVRVPSEEVESPEETDNLIEETAD--DLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWA--------DHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVII-PLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSET-ITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVL-GNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVG--HTWPTEGA-----------VSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSR-ITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAM 1467
MR P P + + VS+KRI+ +LN E+DS +ND S ++I++ + + D +L +N S G LTA+VG VG+GKS LL++ GE+ ++ G + + YV Q W+++ T+RDNI F Q ++S+ Y KV+ CQL D + D T + NG LSGGQ+QR+ ARA+Y +A +YL+DDPLSA D+++ IF + +G L+ KTR+L+T+ + + MD IIV++NG V E S + EV++ E+ +T + EPPK DN + D D+IE K + +Y YV ++GT F + Y ++ + WLSRW D N H D Y+ VYG +G Q + F LL +AS HD +L+ V +P+ FF + P G I+NRFS D+D D +P L + + A L +++ + PI A I+ PLGLI+ V + +++ S+ +KR + + + HF ++ + G +IR Y + ++ E + + + + + + + + L LR++++ G + A E S ++ LS+T +L ++ + R +E V++ERI E E +P DP G + T G+ + F+ ++ +Y + + +K + VR EK+G+ GRTG+GKSSL L+L ++E KG+I IDG D++ +R + IT D LF G++R+NLDP++ +D IWS LD A +K L GL + E G N S+ LI ++DEA +A+ L +++ I +T F T+ IAHR+ +L CD+I V +G IAEFG+P L+ + S K+M
Sbjct: 1 MRIPFRLLPSCISALSQGIVSIKRIDSYLNREEVDSVK----SNDFSKSPRPEDGYSIQVQDCNYSIDKL----KLLKNINFSTRVGELTAVVGKVGSGKSCLLAALCGELNQRGKGSSLINKDLVYVTQNIWLKSATIRDNITFGQPYNSSQYQKVVSLCQLGQDFKDMYRGDLTYLASNGSTLSGGQRQRIGFARAIYQNAQVYLMDDPLSACDSNLKAQIFHNTI-GPKGFLQKKTRLLITNQSSLIPLMDRIIVIQNGTVEEKDSAE-----------------------EVKSFEIAKKSTKKQGSFHEPPK----------------DNYLHPALDNYDIIERRK-----IPFSLYKYYVLNLGTVPFIIALVGYLISQCFDVCSKLWLSRWTNLSSTNINDTNYRHI-YNEDTRNMYIVVYGILGWCQSLAYFLSVLLINSRSLKASSHFHDVILRKVFGAPLNFFWSTPKGTIINRFSKDMDEADMFLPNTLKNFAYQAVKILGTLIIALIAFPITAFFIVCPLGLIFIEVVKSYLMASRFLKRTSATKLAMVLKHFGDSAVHGGTTIRCYGVESDYIDEHMSLIDEHQSVSLMEIISEAXLFLRLQLIAGTFIGILATALVFFPSEGNSSSLSALSLTSSLTVLQDIFLFTRYAAFIEKAMVSIERI-------KECEDLIPQDPSSGLLPSIITNGSKRPKNHQSRYYIQFEDFSGKYSSLKNASIKNFTLNVRLGEKVGVVGRTGSGKSSLILALSGLLEVEKGKIFIDGVDMSSGTARNIRKKDIT----DAALFKGSIRYNLDPDDRFTDEYIWSVLDEAQMKEFFVQLPGGLDFSLKENGSNISLAGSNLI-------------IMDEAXSAMTLESEERILNTYFSRFSSSTIFVIAHRIQPLLACDKILVLENGTIAEFGNPESLIKSQKSIFKSM 874
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000741 (supercontig:LSalAtl2s:LSalAtl2s111:116041:261433:1 gene:EMLSAG00000000741 transcript:EMLSAT00000000741 description:"maker-LSalAtl2s111-snap-gene-2.14") HSP 1 Score: 392.119 bits (1006), Expect = 1.905e-112 Identity = 286/923 (30.99%), Postives = 464/923 (50.27%), Query Frame = 0
Query: 192 VDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKS---PRSMNVTDNVKAFTKQWRKQAEDKL-VDFTSPIRPFVSLWPILFKNHG-----WRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAF-INFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPL-VSFPFTLIESVKVFVSLKRINEFLNASEI-DSTNVIHTANDLSPHA---IEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDEL---KVLATTTKEP-------PKREVRVPSEEVESPEETD----NLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYG---LASVVHALANYWLSRWADHNEAHPETGSDRTGF--------------YLGVYGG-IGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLI 1066
+DI+ + + A+ LS + F W+ LL G +LP + +S ++DN++ ++W+K+ E L D TS R SL L + G + A + +FR+L P QI+ P Q + ++ VL+ S +L + H Y + +++R + LY+KSL+LS + SVG+M N +S D R ++ L ++PL ++ + + ++S+ G + +FIP+ + K +L++ D R+++MNE++ G+KV+K+YAWE PFM + E R EI+ IK AF + F + SS +++ + F + + V+++ IF+ LFN +R L + FP T+ + + VS RI FL EI D + + ++ P IEM + W S++ D L ++ + LTAI+G VG+GKS++L + LGE SG + + G I+Y Q+ WI + T+R NIL + Y KV++ C LE DL RD T +GE G+ LSGGQK R++LAR+VYS+AD+YLLDDPLSAVD+HVG+ ++ + + + L KT +LVTH + +L NII+L G++ + G+ KLL + F+ FL V E ETD + LA T K+ +R+ V S + +T+ N I E V G + +Y Y + G F F+YG L+ ++ ++WL +W + +A ++ + F Y G+Y +G + + S I+ C ++SK +H ++ Q V+ + AFFD NP GRI+NRFS DI +D ++P LSD + + + ++ S+ P V+IPLGLI
Sbjct: 1 MDIEEKVNLKDNKRSNANILSKIFFIWVLPLLRDGQNKAFDIPDLPSALTEDKSRYLSDNLE---REWKKELEKGLRYDNTSKKRYSPSLLRALIRTFGSSLGVYGAFSFIEECVFRLLQPLAISQIVLYFSNSNHGISPT-QLYIWSAVLIMSGVLYVFSHHWYFFGVVQVGMRIRIACSALLYKKSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFIHYLWVAPLQFILVSIITWYMVGISSMCGGAILLVFIPLQTWIGKQFSRLRILIAGKTDKRIRVMNEIIEGMKVIKMYAWEYPFMEVVNETRRDEIQTIKKTYEYKAFNLGFFFTSSRVVLLLIFFLMIIG---NEVISSKNIFLIFGLFNTVRLSLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEVSLRIEMKNVSGKWTSNEKDDD-LRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECI---KNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLLMSERDFTSFL-------VAQEEETDSIFDEDELALTPKKSLNIENYMRRRQSSVSSIGSRATIDTNAMEYNDIPNEGRRTQTTESKVKGSISVALYKKYFYAGGGKWIF--FFVYGLNILSQLLFVSTDWWLKQWTNAADARTNNYANASSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISIRKFLIL-CLKSSKNLHLEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGSLDXLLPLALSDTSLIFLNAVGMFGLIISTEP---KVLIPLGLI 899 HSP 2 Score: 323.553 bits (828), Expect = 2.952e-90 Identity = 224/753 (29.75%), Postives = 369/753 (49.00%), Query Frame = 0
Query: 562 FPFTLIESVKVFVSLKRINEFLNASEI-DSTNVIHTANDLSPHA---IEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDEL---KVLATTTK-----EPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKT------VAGRVGAKVYWTYVQSIGTSQFFTVVFLYGL---ASVVHALANYWLSRWADHNEAHPETGSDRT-GFYLGVYGGIGVVQLILDFSRELLH-------------------------IMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRN-GLDLVLKGIDMEVRSNEKI 1265
FP T+ + + VS RI FL EI D + + ++ P IEM + W S++ D L ++ + LTAI+G VG+GKS++L + LGE SG + + G I+Y Q+ WI + T+R NIL + Y KV++ C L+ DL RD T +GE G+ LSGGQK R++LAR+VYS+ D+YLLDDPLSAVD+HVG+ ++ + + + L KT +LVTH + +L + +NII+L G+ G+ KLL + F FL V E ETD + LA T + E R + + S D + E D E +T V G + +Y Y + G F F+YGL + ++ + ++W +W + +A + G R + Y +++ F +L + I C ++S+ +H ++ Q V+ + AFFD NP GRI+NRFS DI +D ++P LSD + + + ++ S+ P ++ + +I ++++++ S+ +KR E +TKS + + S T+ G+++IRA + ++ F E T F S R+ G V+ G + + A + N+ G G+S++ ++ + + W +R E+E ++ER+ EY SE L D K+ +WP +G + F + +Y + G +LKG+ + S EKI
Sbjct: 1154 FPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEESLRIEMKNVSGKWTSNEKDDD-LRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECI---KKYLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLLMSERDFKPFL-------VAQEEETDSIFHKNELALTPRKSLNIENYMRRRQSSVSSIGSRATIDTNVMEYNDIPNEGRRTQTTESKVKGSISVALYKKYFYADGGKWMF--FFVYGLNISSQLIFVMTDWWXKQWTNAADARKKFGDIRNQKHFFSSYANTSSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISVRKFIFLCLKSSRNLHSEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGALDDLLPIALSDTNLIFLNAVGMSGLIISTEPKILIPLLAILIILLALRKYYLNASRSVKRLEGITKSPVISQLSTTLNGISTIRASKLENNFASEFHYLQDIHTAAFFSFQSVTRFFGFWVD--GIVSINVXATVVIFVFFNVKGGDIGISLSLSVLMARXIQWGLRQSAEVENYMTSVERVAEYGDLPSEKR--LTSDKKIDPSWPNKGVIKFHNVKLKYDDQGGPYILKGLTFTINSFEKI 1889 HSP 3 Score: 69.3218 bits (168), Expect = 7.492e-12 Identity = 64/271 (23.62%), Postives = 123/271 (45.39%), Query Frame = 0
Query: 214 LVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVK-AFTKQWRKQAEDKLV-DFTSPIRPFVSLWPILFKNHG-----WRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKV 477
L+ W+ LL G +L +SP S + + + + ++W+K+ E L+ D TS R SL L + G + + + +FR+L P QI+ P Q + ++ VL+ S +L + + H H + +SL+LS + SVG+M N +S D R ++ L ++PL ++ + + ++S+ G + +FIP+ ++ K + +L++ D R+++MNE++ GI +
Sbjct: 898 LIQRWVFPLLRDGQNKEFDTPDL-QSPLSEDKSRYLSDSLEREWKKELEKGLIYDNTSKKRYSPSLLRALIRTFGSSLGVYGPFVFMENCVFRILQPIAISQIVLYFSNSNHGISPT-QLYIWSAVLIMSGVL-----YVFSHHWHFFGMV-----------QSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFLHYLWVAPLQFILVSMIAWYMVGISSMCGGAILLVFIPLQIWIGKQLSRLRILIAGKTDKRIRVMNEIIEGISL 1150 HSP 4 Score: 63.1586 bits (152), Expect = 6.154e-10 Identity = 58/229 (25.33%), Postives = 96/229 (41.92%), Query Frame = 0
Query: 1246 NGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFN---------------LDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDL-VTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVF-SHGQIAEFGSPAELL 1457
N D L+ + +V E I G G+GKS+ I++A+ G + DI+ G +I+ Q+P +F+G +R N L + D E W DH + E G S GQ+ I LAR++ + + +LD+ +AVD V L + I+ TVI + H++ + D I + + G+I + G+ +LL
Sbjct: 434 NEKDDDLRNVSFQVHKRELTAIIGPVGSGKST-------ILQALLGEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTF---------------VGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECIKNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLL 634 HSP 5 Score: 59.3066 bits (142), Expect = 1.001e-8 Identity = 56/229 (24.45%), Postives = 96/229 (41.92%), Query Frame = 0
Query: 1246 NGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFN---------------LDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDL-VTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVF-SHGQIAEFGSPAELL 1457
N D L+ + +V E I G G+GKS+ I++A+ G + DI+ G +I+ Q+P +F+G +R N L + D E W DH + E G S GQ+ I LAR++ + + +LD+ +AVD V L + I++ TVI + H++ + + + I + + G+ G+ +LL
Sbjct: 1213 NEKDDDLRNVSFQVHKRELTAIIGPVGSGKST-------ILQALLGEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTF---------------VGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECIKKYLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLL 1413
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000002016 (supercontig:LSalAtl2s:LSalAtl2s1361:43077:48755:-1 gene:EMLSAG00000002016 transcript:EMLSAT00000002016 description:"augustus_masked-LSalAtl2s1361-processed-gene-0.2") HSP 1 Score: 317.005 bits (811), Expect = 4.236e-88 Identity = 189/598 (31.61%), Postives = 322/598 (53.85%), Query Frame = 0
Query: 915 FTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAI----FAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEW----------------------------DLPLDPKVGHTW---PTEG-AVSFKSY----ATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAG 1472
F V+ + L SV ++ L W+ E SD+ Y YG + V+ +++ L+ + A+A +H+ ++Q +M P+ F+ P GRI+NR S DI VDQ +P + +I +F ++ + +P+F +P+ IY+++ F+ S++++R +S+T++ + +HFS+T++GL ++RA+ +Q RF++E +V T+ + S RWLG+ ++ G + VF + + F RE S GLS+ Y+L + L W+++ +E A+ER+LEYTH SE E ++ D +V + +EG + F S + YR L + +G +E+ +K+GICGR+G+GKS+L + + R+ ++G I I+G +I + L LR + IPQD VLF+G +R NLDP SD IWS LD A + + GL ++E G+NFS+GQRQ + + +ALLR+ ++++LDE+T+A+D + + +T+ FE T+I++AHRL+ I++ +R+ V G+I E G+P ELL P A+ AG
Sbjct: 1297 FFVILSFVLQSV-KVYMDFLLRDWS-----MEEKNSDKLIAYFSFYGSLSVIVILISCVANLIGQLIGARARTKLHNDMIQNIMYCPLELFEAFPIGRIINRISHDIFIVDQKIPPCIQRLIMLSFVCIAALAXNSIQSPVFLIFALPMISIYWWLXHFYRRSSRELQRLDSITRAPVLSHFSDTLSGLITVRAFGEQTRFINELCEKVDTNTSAFLILQSGCRWLGVYLDAAGAIFVFLSILVNLFFPRKGREVTSSASIGLSVNYSLLVPIYLAWVVKFAANIENYMNAVERVLEYTHFPSEEEDFSEFQAVHASSMNSSRRSFLLRGRGKHDEIEEDVRVSGDFLQNDSEGLIIRFNSVCLAPSFEYRR-LPGIQQGFSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFEDSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGFFSALWRAAG 1887 HSP 2 Score: 204.527 bits (519), Expect = 3.743e-53 Identity = 196/718 (27.30%), Postives = 337/718 (46.94%), Query Frame = 0
Query: 204 LEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIK-----------HMDSNEPV--------WQGFFYT---------IVLLFSSLLSTMAFHAYQQHL-HISAIQMRNSLLGALYQKSLRL----SNKA---RRL----------------------YS------VGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVV-FAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPH---------------------------AIEMTEATLTWDSDDGVDP-----ILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQ--VRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLK-----DKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQ 817
L ++AS S L F WL+ +L QG++ PL+ +L K P+ + TK++ ++ + L S I LW + N + ++ + LF +L + I +++ H+ SN + + FF + +++F + L A HL +S I+ +N+L LY+KSL+L SN R++ YS +G +TN S D I E + + PL IL+ ++ L+ +L ++ ++G ++ + +P+ + K + + L ++D RL E L +K +KL E ++RI R E+ ++ LW+F+ F S LVT G++V ++ H TA +F ++AL + + L P T+ +K VS +R+ EFLN +E+ ++ N L+ H A + E T ++ P +L +NL I GSLT ++G G+GK++L+SS + EM++++G V+ V ++A + Q+ W+ N T++DNIL + F Y KVI C L+ D+ +L H D TEIGE G+ LSGGQ+QR+++AR +YS + +D P S++D+ + +F EG LK +T L T ++FL + D+I+ LK+G + G+ Q
Sbjct: 246 LYNEASSFSRLTFWWLNPILTQGYRAPLEIDDLHKLPK--------EERTKKYFQKLKTLLSRDKSSI-----LWECITMNWSF-VILGGLFRLFADILGYACALSINIIVNSIAAENENASLHLISNVTINPLKDTRYYDSFFVSELFFDPRVVSIVIFLAALGQGALSQTSNHLLTVSGIRAKNALHVLLYEKSLKLPVGSSNPMQIHRKINLKPLNDEGKGCMGGSCSLDEDYSNEGNIDIGFITNLASEDIINIRELIWNVHYIWALPLKILVLLFLLYDQLGISGVSGAILGTCVILPLQVLTGKLMSENNKLILCSQDNRLFKSTETLASMKTVKLATMEEWALKRIRCARTKELIFLRRDSFLWSFMAFLASISTTLVTTLTLGLFVLLE-DHNFTAADLFTSMALLSQLTVCLSVVPVTVPIFIKGKVSTQRLAEFLNRAEV---SIYKQNNKLNKHCTYFDDRKDDDEEEEEEEEESEIFIQRAKRLPETCFTVENGTFAWPKCETNVLQSINLEIKTGSLTIVIGPSGSGKTALISSLIEEMDRITGSVKWNVPDTVALLGQRPWLLNTTIKDNILLGRPFKEKRYKKVIAACDLQTDIDLLPHGDDTEIGERGVLLSGGQRQRLAIARCLYSKSYCTFMDAPFSSLDSKITSHVF------EEGVLKILLKRRRTVFLTTERLDFLHRADHIVALKDGMIKAQGTIQ 939 HSP 3 Score: 67.781 bits (164), Expect = 2.630e-11 Identity = 51/213 (23.94%), Postives = 97/213 (45.54%), Query Frame = 0
Query: 627 MNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRG-------------SIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAF 826
+L IP I G G+GKS+LL + L G + + G + +PQ A + + T+R N+ + +FS + + T + ENG N S GQ+Q +++ +A+ + +LD+ SA+D + A+ +L++ E D T + V H ++ + + + ++V+ G++ E G+ ++LL F
Sbjct: 1670 FSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFE----DSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGF 1878
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000007660 (supercontig:LSalAtl2s:LSalAtl2s445:12562:17493:1 gene:EMLSAG00000007660 transcript:EMLSAT00000007660 description:"maker-LSalAtl2s445-augustus-gene-0.18") HSP 1 Score: 135.191 bits (339), Expect = 1.344e-32 Identity = 139/501 (27.74%), Postives = 221/501 (44.11%), Query Frame = 0
Query: 989 IHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFAS---VIIP---LGLIYF--FVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAV---------LSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVG------HTWPTEGAVSFK----SYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRIL-IDGQDIAQLGLHTLR-SRITIIPQDPVLFTG----NLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAEL 1456
+ L ++ +AFFD + TG IV+R S+D+ +S + + IV + +P S VI+P LG Y +++ Q+ +A +V + E I+ + ++R + +D + V K + N LGL + V FF + +S +NL+PG + I ++ + + L + RI EY +PL P G H++ G V FK SY TR VLK + + ++ + + G +G GK+++ L R + G L IDG +I L LR S I I Q+PVLF N+R+ PN +D E++ A AH+ + G + E G S GQ+Q I +ARALL+ IL+LDEAT+A+D ++ ++Q + + + T + IAHRL+TI + D IAV G +AE G+ A L
Sbjct: 188 LRKDLFNSIICQDIAFFDEHKTGEIVSRLSADVQEFKSSFKLVISQGLRSSAQASGCIVSMYMISPQMTSAMGVIVPTVILGGTYIGSYLRVLSKKAQAQVAKATAVGE--------ECISNIRTVRGFAMEDAEMELYSREVDKTRDF-------NEALGLGIGVFQGASNFFLNSIVLGTITYGGYLMSDDNLNPGQLMSFLVSVQTIQRSITQVSLLFGHLVKGMASGSRIFEYIEK-------VPLIPISGGVKIPYHSF--FGDVEFKNITFSYPTRPEQA---VLKDFSLRIPPSKTVALVGTSGGGKTTIAALLERFYDINGGGSLEIDGINIRDLDPSWLRGSAIGYINQEPVLFATSVIENIRYG-RPNA--TDNEVYEAAKAAHVDDFVRTFPDGYSTILGERGVTVSGGQKQRIAIARALLKNPPILILDEATSALDAESERIVQEALDKLSKGRTSLVIAHRLSTIKNADVIAVIDKGVMAEIGTHAAL 658 HSP 2 Score: 84.3445 bits (207), Expect = 1.193e-16 Identity = 130/586 (22.18%), Postives = 249/586 (42.49%), Query Frame = 0
Query: 292 ALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVL--LFSSLLSTMAFHAYQQHLHIS------------AIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMM--GLIMSPLT--ILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKC---VKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFM----RRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHA----IEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSS---LLSSFL-----GEMEKLSGQVQ------VRGS-IAYVPQQAWIQNMTLRDNILFDQEFSSTNYT-KVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQ 832
A+ VA F + +P + I+ ++ ++ +E V + L + LS + F+A Q I+ A +R L ++ + + ++ + GE+ + +S D Q +F ++ GL S +++MY + ++ S G++V + + GS KK Q Q +A + E + I+ ++ +A E M R + + R + G NF + +S +L TI +G Y+ D L ++ + ++ + VK S RI E++ + I + H+ +E T ++ + +L +L IP A+VGT G GK++ LL F G +E ++ +RGS I Y+ Q+ + ++ +NI + + ++ N + + ++ + T +GE G+ +SGGQKQR+++ARA+ + I +LD+ SA+DA + I + LD K +T +++ H ++ + D I V+ G +AE G++ L G +S + Q
Sbjct: 110 AIAVAYFNIKIPLLLGDIVNVVSSYI--SETVLSEMRHDNFLREMKEPTLSMIKFYAAQSICTIAYIYSLACLGERMAASLRKDLFNSIICQDIAFFDE----HKTGEIVSRLSADVQEFKSSFKLVISQGLRSSAQASGCIVSMYMISPQMT--SAMGVIVPTVILGGTYIGSYLRVLSKKAQAQVAKAT----AVGEECISNIRTVRGFAMEDAEMELYSREVDKTRDFNEALGLGIGVFQGASNF-FLNSIVLGTI-TYGGYLMSDDN--LNPGQLMSFLVSVQTIQRSITQVSLLFGHLVKGMASGSRIFEYIEKVPLIP---ISGGVKIPYHSFFGDVEFKNITFSYPTRPE-QAVLKDFSLRIPPSKTVALVGTSGGGKTTIAALLERFYDINGGGSLEIDGINIRDLDPSWLRGSAIGYINQEPVLFATSVIENIRYGRPNATDNEVYEAAKAAHVDDFVRTFPDGYSTILGERGVTVSGGQKQRIAIARALLKNPPILILDEATSALDAE-SERIVQEALDKLS---KGRTSLVIAHRLSTIKNADVIAVIDKGVMAEIGTHAALKRKGGIYSRLIEQ 671
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|82231164|sp|Q5F364.1|MRP1_CHICK (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1159.82 bits (2999), Expect = 0.000e+0 Identity = 641/1534 (41.79%), Postives = 920/1534 (59.97%), Query Frame = 0
Query: 11 DPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIY-QTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVE--EWVLLITYVPIILGLFIAHCWVDIDPRAAEDLS-----LEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDN--------VKAFTKQWRKQAEDKLVDFTSP---------------------IRPF-----VSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNE-PVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTS---------------------------NPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDR-TGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
+PF+D +L W+T +P+ TQC ++T+LV VPCI + + +Y ++ RG + L AK L++ + Y+ + P L L + + LA ++ G S + +FWL L+C + I + V+ +V TY ++L I C+ + P +E ++ E AS LS + F W+ GL+ QGH+ PL+ K+L S+N D K + K+W K L S I+P SL +L+K G L++ + LL F P+I+KLLI +++ P WQG+FYT +L + L T+ H Y ++ ++++ +++G +Y+K+L ++N AR+ +VGE+ N MSVDAQR ++ Y+ + +PL +++A+Y L+ L + LAG+ V + +PIN + K QV Q+++KD R+KLMNE+L GIKVLKLYAWE+ F ++ EIR E+K++K L A F++ +P LV + F +YV ++ ++L A K FV++ALFN++R PL P + V+ VSLKR+ FL+ E+D ++I + +I + AT +W D P L+ +N ++P GSL A+VG VG GKSSLLS+ LGEM+K G V V+GSIAYVPQQAWIQN TL DNI+F +E + + Y +VI C L PDL IL DRTEIGE G+NLSGGQKQRVSLARAVY +AD YL DDPLSAVDAHVGK IF +V+ +G LK+KTRVLVTH VN+L +MD I+V+ +G+++E GSYQ+LL AF+EFL Y + N T ++ +L +T ++E K + + + E++ P L E+ + L E + GRV A VYW Y+++IG F VFL+ + +NYWLS W D + G+ + T LGVYG +G+ Q I F + + AS+ +H LL V+RSPM+FF+ P+G +V+RFS +ID +D +P + + F+ + +++ +TPI A VI PLGL+Y VQRF+V S+Q+KR ESV++S +++HF+ET+ G++ IRA+++Q RF+ ++ +V + + ++ ANRWL +R+E +GN +V FAA+FAV++R LSPG+ GLS++Y+L I LNW++RM +LETN VA+ER+ EY E EAEW + + TWP EG V F+ + RYR LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI EA +G I+IDG +IA++GLH LR +ITIIPQDP+LF+G+LR NLDP + HSD +IW +L+ AHLK +S L L HE SEGGEN SVGQRQL+CLARALLRK+KILVLDEATAAVDL TD+LIQSTI+ +FE CTV+TIAHRLNTI+D R+ V G++ E SP LL +M D+GL
Sbjct: 13 EPFWDWNLTWHTENPDFTQCFQNTVLVWVPCIYLWVCFPAYFLYLRSHDRGYI-----QMSILNKAKTALGLILWIVCWADLFYSFWERSQNIFRAPFFLISPTVLGITMLLATFLIQHERLKGVQSSGVMMIFWLISLLCATVIFRSKIMLALNTDTEVDAFRYVTFCTYFILLLVQLILSCFPEKPPLFSEAVNDPKPCPEFSASFLSRITFWWITGLMIQGHRRPLEAKDL----WSLNKEDTSEEIVPGLAKNWAKEWAKTKRQPLNMLYSSKKQQKSSDSNGEVMEEAEALIIKPSQRSSEASLSKVLYKTFGPYFLMSFLFKAAHDLLMFTGPEILKLLINFVNNKSAPNWQGYFYTGLLFVCACLQTLILHQYFHICFVTGMRLKTAIVGVIYRKALVITNSARKTSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPSVLAGVAVMILLVPINAVMAMKTKTYQVAQMKSKDNRIKLMNEILNGIKVLKLYAWELAFREKVLEIRQKELKVLKKSAYLAAMGTFTWVCAPFLVALSTFAVYVKVNKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVEASVSLKRLRVFLSHEELDPDSIIRGPITNAEGSIVVKNATFSWSKTD--PPSLNSINFTVPEGSLIAVVGQVGCGKSSLLSALLGEMDKKEGYVVVKGSIAYVPQQAWIQNATLEDNIIFGREMNESRYKRVIEACALLPDLEILPMGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADTYLFDDPLSAVDAHVGKHIFEKVI-GPKGILKNKTRVLVTHAVNYLPQMDTILVMTDGEISEMGSYQELLKQDGAFAEFLRTYANAEQSMESSDASSPSGKEGKPVENGVLVNDATGKLMHRQLSNSSTYSRETGKSQHQSSTAELQKP-----LAEKNSWKLTEADTAKTGRVKATVYWEYMKAIGLYISFLSVFLFMCNHIASLASNYWLSLWTDDPVVN---GTQQYTNVRLGVYGALGISQGIAVFGYSMAVSIGGIFASRHLHLDLLHNVLRSPMSFFERTPSGNLVSRFSKEIDTIDSTIPPIIKMFMGSTFNVIGACIIILLATPIAAVVIPPLGLVYLLVQRFYVATSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQKRFIKQNDMKVDENQKAYYPSIVANRWLAVRLEFVGNCIVLFAALFAVIARNKLSPGLIGLSVSYSLQITAYLNWLVRMTSDLETNIVAVERVKEYAEMEKEAEWSIE-ETAPASTWPQEGKVEFRGFGLRYREDLDLVLKNINITINGGEKVGIVGRTGAGKSSLTLGLFRINEAAEGEIIIDGINIAKIGLHDLRFKITIIPQDPILFSGSLRMNLDPFDQHSDEDIWRSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDNLIQSTIKSQFEECTVLTIAHRLNTIMDYTRVLVLDRGEVVECDSPDNLL-QAKGLFYSMAKDSGL 1524
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|296439301|sp|P33527.3|MRP1_HUMAN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1134.4 bits (2933), Expect = 0.000e+0 Identity = 630/1539 (40.94%), Postives = 914/1539 (59.39%), Query Frame = 0
Query: 6 RPFCR----DPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEW--VLLITYVPIILGLFIAHCWVDIDPRAAEDL-----SLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQA---------------------EDKLVDFTSPIRPFV----------SLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEI--DSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKRE--------------------------VRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
R FC DP +D ++ WNT++P+ T+C ++T+LV VPC + +Y + R + PL K ++ + Y+ L P L L + + LA +++ G S + FWL L+C + L+ I + + V+ + + Y ++L + C+ D P +E + E AS LS + F W+ GL+ +G++ PL+ +L + V K W+K+ E VD + + SL+ +L+K G L++ L+ F PQI+KLLIK + D+ P WQG+FYT++L ++ L T+ H Y +S ++++ +++GA+Y+K+L ++N AR+ +VGE+ N MSVDAQR ++ Y+ + +PL +++A+Y L+ L + LAG+ V + +P+N + K QV +++KD R+KLMNE+L GIKVLKLYAWE+ F ++ IR E+K++K L A F++ +P LV + F +YV +D ++L A FV++ALFN++R PL P + V+ VSLKR+ FL+ E+ DS + ++I + AT TW D P L+ + SIP G+L A+VG VG GKSSLLS+ L EM+K+ G V ++GS+AYVPQQAWIQN +LR+NILF + Y VI+ C L PDL IL DRTEIGE G+NLSGGQKQRVSLARAVYS+ADIYL DDPLSAVDAHVGK IF V+ +G LK+KTR+LVTH++++L ++D IIV+ GK++E GSYQ+LLA AF+EFL Y S + E + + ++ KE + E + ++ + EET L+E +K G+V VYW Y+++IG F +FL+ V +NYWLS W D + + T L VYG +G+ Q I F + + AS+ +H LL ++RSPM+FF+ P+G +VNRFS ++D VD ++P + + F+ + +V+ +TPI A +I PLGLIYFFVQRF+V S+Q+KR ESV++S +++HF+ET+ G++ IRA+++Q+RF+H+S +V + + ++ ANRWL +R+E +GN +V FAA+FAV+SR +LS G+ GLS++Y+L + LNW++RM E+ETN VA+ER+ EY+ E EA W + + +WP G V F++Y RYR LD VL+ I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+IDG +IA++GLH LR +ITIIPQDPVLF+G+LR NLDP +SD E+W++L+ AHLK +S L L HE +EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQSTIR +FE CTV+TIAHRLNTI+D R+ V G+I E+G+P++LL +M DAGL
Sbjct: 4 RGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLS----RHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSD--PPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVI-GPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWK-LMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTD--DPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ-ETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQ-RGLFYSMAKDAGL 1530
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|52783101|sp|O35379.1|MRP1_MOUSE (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1132.86 bits (2929), Expect = 0.000e+0 Identity = 633/1543 (41.02%), Postives = 920/1543 (59.62%), Query Frame = 0
Query: 6 RPFCR----DPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTW-------TRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLL-VFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEW--VLLITYVPIILGLFIAHCWVDIDPRAAEDL-----SLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAE----------------------DKLVDFTSPIRPFV----------SLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNE-PVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTA-NDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELK--------------VLATTTKEPPKREVRVPSEEVESPEETDNLIE-------ETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALA-NYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
R FC DP +D ++ W+T++P+ T+C ++T+L VPC +WS + + RG L F + ++ +L F S V + L+ S P LL + + LA +++ G S + FWL L+C + L+ I S + V+ + Y ++L + C+ D P +E + E AS LS + F W+ G++ G++ PL+ +L + + V W+K+ + +D + + SL+ +L+K G L++ + L+ F P+I++L+I ++ E P WQG+FYT +L S+ L T+A H Y +S ++++ +++GA+Y+K+L ++N AR+ +VGE+ N MSVDAQR ++ Y+ + +PL +++A+YFL+ L + LAG+ V + +P+N + K QV +++KD R+KLMNE+L GIKVLKLYAWE+ F ++ IR E+K++K L A F++ +P LV + F ++V +D ++L A K FV++ALFN++R PL P + V+ VSLKR+ FL+ E++ ++ + ++I + AT TW G P L+ + SIP G+L A+VG VG GKSSLLS+ L EM+K+ G V ++GS+AYVPQQAWIQN +LR+NILF Y V+ C L PDL IL DRTEIGE G+NLSGGQKQRVSLARAVYS++DIYL DDPLSAVDAHVGK IF +V+ G LK+KTR+LVTH +++L ++D IIV+ GK++E GSYQ+LL AF+EFL Y + E D + V T K + S ++ ++ ++ E E L+E +K G+V VYW Y+++IG F +FL+ L + V ALA NYWLS W D T ++R F L VYG +G++Q F + + AS+ +H LL V+RSPM+FF+ P+G +VNRFS ++D VD ++P + + F + ++++ +TPI A +I PLGL+YFFVQRF+V S+Q+KR ESV++S +++HF+ET+ G++ IRA+++Q+RF+H+S +V + + ++ ANRWL +R+E +GN +V FAA+FAV+SR +LS G+ GLS++Y+L I LNW++RM E+ETN VA+ER+ EY+ E EA W + + TWP G V F+ Y RYR LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+IDG +IA++GLH LR +ITIIPQDPVLF+G+LR NLDP +SD E+W AL+ AHLKG +S L L HE +EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TD+LIQSTIR +FE CTV+TIAHRLNTI+D R+ V G++ E G+P+ELL +M DAGL
Sbjct: 4 RSFCSADGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFY------LWSCFPLYFFYLSRHDRGYIQMTHLNKTKTALGFFLW-IICWADLFYSFWERSQGVLRAPVLLVS-----PTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAHVDVFRDSTFYLYFTLVLVQLVLSCFSDCSPLFSETVHDRNPCPESSASFLSRITFWWITGMMVHGYRQPLESSDLWSLNKEDTSEEVVPVLVNNWKKECDKSRKQPVRIVYAPPKDPSKPKGSSQLDVNEEVEALIVKSPHKDREPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPKILELIINFVNDREAPDWQGYFYTALLFVSACLQTLALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVKNATFTWAR--GEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPM-GLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFLRTYANAEQDLASEDDSVSGSGKESKPVENGMLVTDTVGKHLQRHLSNSSSHSGDTSQQHSSIAELQKAGAKEETWKLMEADKAQTGQVQLSVYWNYMKAIGLFITFLSIFLF-LCNHVSALASNYWLSLWTDDPPVVNGTQANRN-FRLSVYGALGILQGAAIFGYSMAVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ-ETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQ-RGIFYSMAKDAGL 1527
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|75072869|sp|Q864R9.1|MRP1_MACFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1130.93 bits (2924), Expect = 0.000e+0 Identity = 631/1539 (41.00%), Postives = 911/1539 (59.19%), Query Frame = 0
Query: 6 RPFCR----DPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQT-WTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEW--VLLITYVPIILGLFIAHCWVDIDPRAAEDL-----SLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQA---------------------EDKLVDFTSPIRPFV----------SLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEI--DSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREV------------------------RVPSEEVESPE-ETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
R FC DP +D ++ W T++P+ T+C ++T+LV VPC + +Y + RG L F +V +L F S + L P L L + + LA +++ G S + FWL L+C + L+ I + + V+ + + Y ++L + C+ D P +E + E AS LS + F W+ GL+ +G++ PL+ +L + V K W+K+ + VD + + SL+ +L+K G L++ L+ F P+I+KLLI + D+ P WQG+FYT +L ++ L T+ H Y +S ++++ +++GA+Y+K+L ++N AR+ +VGE+ N MSVDAQR ++ Y+ + +PL +++A+Y L+ L LAG+ V + +P+N + K QV +++KD R+KLMNE+L GIKVLKLYAWE+ F ++ IR E+K++K L A F++ +P LV + F +YV +D +VL A K FV++ALFN++R PL P + V+ VSLKR+ FL+ E+ DS + ++I + AT TW D P L+ + SIP G+L A+VG VG GKSSLLS+ L EM+K+ G V ++GS+AYVPQQAWIQN +L++NILF + Y VI+ C L PDL IL DRTEIGE G+NLSGGQKQRVSLARAVY +ADIYL DDPLSAVDAHVGK IF V+ +G LK+KTR+LVTH++++L ++D IIV+ GK++E GSYQ+LLA AF+EFL Y S + E + + ++ KE + E V + + E + D +E L+E +K G+V VYW Y+++IG F +FL+ V +NYWLS W D + + T L VYG +G+ Q I F + + AS+ +H LL ++RSPM+FF+ P+G +VNRFS ++D VD ++P + + F+ + +V+ +TPI A +I PLGLIYFFVQRF+V S+Q+KR ESV++S +++HF+ET+ G++ IRA+++Q+RF+H+S +V + + ++ ANRWL +R+E +GN +V FAA+FAV+SR +LS G+ GLS++Y+L + LNW++RM E+ETN VA+ER+ EY+ E EA W + + WP G V F++Y RYR LD VL+ I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+IDG +IA++GLH LR +ITIIPQDPVLF+G+LR NLDP +SD E+W++L+ AHLKG +S L L HE +EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQSTIR +FE CTV+TIAHRLNTI+D R+ V G+I E+G+P++LL M DAGL
Sbjct: 4 RGFCSADGSDPLWDWNVTWYTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTLLNKTKTALG-FLLWIVCWADLFYSFWERSRGIF----LAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEDVQVDLFRDMTFYVYFSLVLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKDSSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPEILKLLINFVNDTKAPDWQGYFYTALLFVAACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPPILAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALCTFAVYVTIDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGDTNSITVRNATFTWARSD--PPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVALKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVI-GPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQDPEDNGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDVSRQHNSTAELQKDGAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFICNHVAALASNYWLSLWTD--DPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ-ETAPPSNWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQ-RGLFYNMARDAGL 1530
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|85701143|sp|Q8CG09.2|MRP1_RAT (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1128.24 bits (2917), Expect = 0.000e+0 Identity = 629/1539 (40.87%), Postives = 910/1539 (59.13%), Query Frame = 0
Query: 8 FCR----DPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTW--TRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEW--VLLITYVPIILGLFIAHCWVDIDPRAAEDL-----SLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQA----------------------EDKLVDFTSPIRPFV----------SLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNE-PVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEI--DSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKE----------------PPKREVRVPS--------EEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALA-NYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC DP +D ++ W+T++P+ T+C ++T+L VPC +WS + + R + L AK + + Y+ L P L L + + LA ++ G S + FWL L+C + L+ I S + V+ + Y ++ + C+ D P +E + E AS LS + F W+ G++ QG++ PLK +L + + V W+K+ +D + + SL+ +L+K G L++ + L+ F P+I++L+I ++ E P WQG+ YT +L S+ L T+A H Y ++ ++++ +++GA+Y+K+L ++N AR+ +VGE+ N MSVDAQR ++ Y+ + +PL + +A+YFL+ L + LAG+ V + +P N + K QV +++KD R+KLMNE+L GIKVLKLYAWE+ F ++ IR E+K++K L A F++ +P LV + F ++V +D ++L A K FV++ALFN++R PL P + V+ VSLKR+ FL+ E+ DS + ++I + AT TW D+ P L+ + +IP G+L A+VG VG GKSSLLS+ L EM+K+ G V ++GS+AYVPQQAWIQN +LR+NILF + Y V+ C L PDL IL D TEIGE G+NLSGGQKQRVSLARAVY ++DIYLLDDPLSAVDAHVGK IF +V+ G LK+KTR+LVTH +++L ++D IIV+ GK++E GSYQ+LL AF+EF+ Y + E D ++ KE P +R + S + + E + ++E L+E +K G+V VYW Y+++IG F +FL+ L + V ALA NYWLS W D A T +R F L VYG +G++Q + F + + AS+ +H LLQ V+RSPM+FF+ P+G +VNRFS ++D VD ++P + + F + ++++ +TPI A +I PLGL+YFFVQRF+V S+Q+KR ESV++S +++HF+ET+ G++ IRA+++Q+RF+ +S +V + + ++ ANRWL +R+E +GN +V FAA+FAV+SR +LS G+ GLS++Y+L I LNW++RM E+ETN VA+ER+ EY+ E EA W + + TWP G V F+ Y RYR LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+IDG +IA++GLH LR +ITIIPQDPVLF+G+LR NLDP +SD E+W AL+ AHLKG +S L L HE +EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQSTIR +FE TV+TIAHRLNTI+D R+ V G+I E G+P+ELL +M DAGL
Sbjct: 6 FCSSDGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFY------LWSCFPLYFLYLSRHDRGYIQMTHLNKAKTALGFFLWIICWADLFYSFWERSQGMLLAPVLLVSPTLLGITMLLATFLIQFERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAQVDMFRDSAFYLYFTLVFIQLVLSCFSDSSPLFSETVRDPNPCPESSASFLSRITFWWITGMMVQGYRQPLKSSDLWSLNKEDTSEEVVPVLVNNWKKECVKSRKQPVRIVYAPPKDPTKPKGSSQLDVNEEVEALIVKSSHKDRDPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPEILELIINFVNDREAPDWQGYLYTALLFVSACLQTLALHQYFHICFVTGMRIKTAVVGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMNSITVKNATFTWARDE--PPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPM-GLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFVRTYANTEQDLASEDDSKNGVSGLGKESKPVENGILVTDAVGKPLQRHLSNSSSHSVVTNQQHSSTAELQKSGVKEETWKLMEADKAQTGQVKLSVYWNYMKAIGLCISFLSIFLF-LCNHVSALASNYWLSLWTDDRPAVNGTQENRN-FRLSVYGALGILQGVAVFGYSMAVSIGGIFASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEASWQIQ-ETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQ-RGVFYSMAKDAGL 1531
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|75071939|sp|Q6UR05.1|MRP1_CANFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1127.46 bits (2915), Expect = 0.000e+0 Identity = 634/1539 (41.20%), Postives = 916/1539 (59.52%), Query Frame = 0
Query: 6 RPFCR----DPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEW--VLLITYVPIILGLFIAHCWVDIDPRAAE---DLSL--EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQA-----EDKLVDFTS--PIRPF------------------------VSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEI--DSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIE-------------------------ETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDL-PLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
R FC DPF++ D+ WNT++P+ T+C ++T+LV VPC + + +Y +R + Y L K V+ + Y+ L P L L + + LA +++ G S + FWL L+C + L+ I + + ++ + V Y ++L + C+ D P +E DL+ E AS LS + F W+ GL+ +G++ PL+ +L + V K W+K+ + + + ++S P +P SL+ +L+K G L++ + L+ F P+I+KLLI + D P WQG+ YT +L + L T+ H Y +S ++++ +++GA+Y+K+L ++N AR+ +VGE+ N MSVDAQR ++ Y+ + +PL +++A+Y L+ L + LAG+ V + +P+N + K QV +++KD R+KLMNE+L GIKVLKLYAWE+ F ++ IR E+K++K L A F++ +P LV + F +YV +D ++L A K FV++ALFN++R PL P + V+ VSLKR+ FL+ E+ DS + ++I + AT TW D P LS + SIP GSL A+VG VG GKSSLLS+ L EM+K+ G V ++GS+AYVPQQAWIQN +LR+NILF ++ Y VI C L PDL IL DRTEIGE G+NLSGGQKQRVSLARAVY D+DIYL DDPLSAVDAHVGK IF V+ +G LK+KTR+LVTH++++L ++D IIV+ GK++E GSYQ+LLA AF+EFL Y S + D L +++ KE + E + +V + L E A L+E +K G+V VYW Y+++IG F +FL+ V ++NYWLS W D + + T L VYG +G+ Q I F + + AS+ +H LLQ V+RSPM+FF+ P+G +VNRFS ++D VD ++P + + F+ + +++ +TPI + +I PLGLIYFFVQRF+V S+Q+KR ESV++S +++HF+ET+ G++ IRA+++Q+RF+ +S +V + + ++ ANRWL +R+E +GN +V FAA+F+V+SR +LS G+ GLS++Y+L + LNW++RM E+ETN VA+ER+ EY+ E EA W + + P TWP G V F+ Y RYR LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+ID +IA++GLH LR +ITIIPQDPVLF+G+LR NLDP +SD E+W++L+ AHLK +S L L E +EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQSTIR +F+ CTV+TIAHRLNTI+D R+ V G+I E G P++LL +M DAGL
Sbjct: 4 RGFCSADGSDPFWEWDVSWNTSNPDFTKCFQNTVLVWVPCCYLWLCFPFYFLY--LSRHDRGYIQMTY--LNKTKTALGFVLWIVCWADLFYSFWERSWGKILAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDAEIDVFRDVTFYIYFSLVLIQLVLSCFSDRPPLFSETIHDLNPCPESSASFLSRVTFWWITGLMVRGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQRKITYSSKDPAKPKGGSQVDVNEEAEVLIVKTPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDKKAPDWQGYLYTALLFICACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGANSITVKNATFTWARSD--PPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVI-GPKGMLKNKTRLLVTHSISYLPQVDVIIVMTGGKISEMGSYQELLARDGAFAEFLRTYASGDQEQAEQDDGLTGVSSPGKEVKQMENGMLVTDVAGKQLQRQLSNSSSYSGDVSRHHTSTAELQKAGPKNEDAWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTD--DPIVNGTQEHTKIRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHVDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIASIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFSVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQEMAPP--STWPQVGRVEFRDYGLRYRENLDLVLKHINITINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRVKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGQPSDLLQQ-RGLFYSMAKDAGL 1530
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|75072999|sp|Q8HXQ5.1|MRP1_BOVIN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1125.92 bits (2911), Expect = 0.000e+0 Identity = 632/1543 (40.96%), Postives = 913/1543 (59.17%), Query Frame = 0
Query: 6 RPFCR----DPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTW-TRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEW--VLLITYVPIILGLFIAHCWVDIDPRAAEDLS-----LEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQW-------RKQAEDKLVDFTSPIRPF------------------------VSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIH--TANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREV-----------------------------RVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
R FC D F++ ++ WNT++P+ T+C ++T+LV VPC + + +Y + RG L AK ++ + Y+ L P L L + + LA +++ G S + FWL L+C + L+ I + + V+ + V Y ++L + C+ D P +E ++ E AS LS + F W+ G++ QG++ PL+ +L + V K W RKQ + P +P SL+ +L+K G L++ + L+ F P+I+KLLI + D P WQG+FYT +L S+ L T+ H Y +S ++++ +++GA+Y+K+L ++N AR+ +VGE+ N MSVDAQR ++ Y+ + +PL +++A+Y L+ L + LAG+ V + +P+N + K QV +++KD R+KLMNE+L GIKVLKLYAWE+ F ++ IR E+K++K L A F++ +P LV + F +YV +D ++L A K FV++ALFN++R PL P + V+ VSLKR+ FL+ ++D ++ + + ++I + AT TW +D P L + S+P GSL A+VG VG GKSSLLS+ L EM+K+ G V V+GS+AYVPQQAWIQN++LR+NILF ++ Y V+ C L PDL IL DRTEIGE G+NLSGGQKQRVSLARAVY D+D+YLLDDPLSAVDAHVGK IF V+ +G LK+KTR+LVTH +++L +MD IIV+ GK++E GSYQ+LLA AF+EFL Y S D L + KE + E + E+ P T EET L+E +K G+V VYW Y+++IG F +FL+ V ++NYWLS W D + + T L VYG +G+ Q I F + + AS+ +H LL V+RSP++FF+ P+G +VNRFS ++D VD ++P + + F+ + +++ +TP+ A +I PLGLIYFFVQRF+V S+Q+KR ESV++S +++HF+ET+ G++ IRA+++Q+RF+ +S +V + + ++ ANRWL +R+E +GN +V FA++FAV+SR +LS G+ GLS++Y+L + LNW++RM E+ETN VA+ER+ EY+ E EA W + D WP G V F+ Y RYR LDLVLK I++ + EK+GI GRTGAGKSSLTL LFRI E+ +G I+ID +IA++GLH LR +ITIIPQDPVLF+G+LR NLDP +SD E+W++L+ AHLKG +S L L HE +EGGEN SVGQRQL+CLARALLRKTKILVLDEATAAVDL TDDLIQSTIR +F+ CTV+TIAHRLNTI+D R+ V G+I E+GSP++LL +M D+GL
Sbjct: 4 RDFCSVDGSDLFWEWNVTWNTSNPDFTKCFQNTVLVWVPCSYLWVCFPFYFLYLSHHDRGYIQMTH-----LNKAKTALGFLLWIVCWADLFYSFWERSMGKLLAPVFLVSPTLLGITMLLATFLIQIERRRGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDARVDVFRDVTFYIYFSLVLIQLVLSCFSDRSPLFSETINDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSRKQPVKIVYSSKDPAKPKGSSKVDVNEEAEALIVKCPQKERDPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKDAGATNSITVKNATFTWARND--PPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVI-GPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQGQPEDGLAGVGGPGKEVKQMENGMLVTDTAGKQMQRQLSSSSSYSRDVSQHHTSTAELRKPGPT----EETWK-LVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTD--DPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ-DMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQ-RGLFYSMAKDSGL 1529
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|218526606|sp|B2RX12.1|MRP3_MOUSE (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1100.12 bits (2844), Expect = 0.000e+0 Identity = 629/1527 (41.19%), Postives = 919/1527 (60.18%), Query Frame = 0
Query: 13 FFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVIL---VNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVG--LALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVE--EWVLLITYVPIILGLFIAHCWVDIDPR-AAEDLSL----EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQ-----------------AEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSP-HAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVE------TDELKVLAT--------TTKEPPKREVR---------VPSE-EVES---PEETDNLIEETA--------DDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
F+D +L T P++T C +++LL VPCI +L A+L ++ V S +L++ L +L V+ + F G + GS P+ +F L+V + LA L ++ G S L +FWL +IC I + I S + ++ + Y ++ I C+ + P + E+L E A S L F W L G++ PL+ ++L V+ + W+KQ ED ++ P S L + L++ L + LL FV+PQ++ +LI+ + D P W GF ++ SS + T+ H Y + + A+++R +++G +Y+K+L ++N +R +VGEM N MSVDAQR ++ P++ L +PL +++A+YFL+ L ++LAG+ V + IP+N S +K QV+Q++ KD+R+KLM+E+L GIKVLKLYAWE F+ ++ IR +E+++++ L A F + +P LVT+ G+YV +D ++VL A+K FV+++LFN+++ PL P + + VSLKRI +FLN +E+D V +SP +AI + T TW D + P L +N+ IP G+L A+VG VG GKSSL+S+ LGEMEKL G V V+GS+AYVPQQAWIQN TL++N+LF Q + Y + + C L DL +L D+TEIGE GINLSGGQ+QRVSLARAVYSDA+I+LLDDPLSAVD+HV K IF QV+ EG L KTRVLVTH ++FL + D IIVL G+V+E G Y LL +F+ FL Y + + E +E+ +L T EP EVR + SE EV++ P++ N +E+ A LI+EE G V VYW Y +S+G ++ LYG S AN WLS W++ E H + ++T LGVY +G++Q +L ++ QA++++H+ LL +RSP +FFDT P+GRI+NRFS DI +D+V+ + ++ F ++S I+V+ +STP+F V++PL ++Y FVQRF+V S+Q+KR ES+++S IF+HFSET+TG + IRAY + F S +V ++ +++NRWLG+ VE +GN VV FAA+FAV+ R +L+PG+ GLS++YAL + LNWMIRM+ +LE+N +A+ER+ EY+ ++EA W + + + WPT G V F++Y+ RYR GL+LVLK + + V+ EK+GI GRTGAGKSS+TL LFRI+EA +G I+IDG ++A +GLH LRS++TIIPQDP+LF+G LR NLDP +S+ +IW AL+ +HL +S GL + +EGG+N SVGQRQL+CLARALLRK+++LVLDEATAA+DL TDDLIQ TIR +FE CTV+TIAHRLNTI+D +R+ V G +AEF SP L+A M DAGL
Sbjct: 14 FWDSNLSIYTNTPDLTPCFQNSLLAWVPCI-YLWAALPCYLFYLRHHQLGYIVLS-----WLSRLKTALGVLLWCVSWVDLFYSFHGLIHGSS---PAPVFFVTPLVVGITMLLATLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSALAEGKILDPFRFTTFYIYFALVFCALILSCFKEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASGSQTATAEPKIPGEDAVLLKPRPKSKQPSFLRALVRTFTSSLLMSACFNLIQNLLGFVNPQLLSILIRFISDPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCV--ERKTISPGYAITIHNGTFTWAQD--LPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVI-GPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLEDTLSTHTDLTDNEPAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTKETGALIKEEIAETGNVKLSVYWDYAKSMGLCTTLSICLLYGGQSAAAIGANVWLSAWSNDAEEHGQ--QNKTSVRLGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTEAPWVVESN-RAPEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAKDAGL 1522
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|6920069|sp|O15438.3|MRP3_HUMAN (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multi-specific organic anion transporter D; Short=MOAT-D; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1069.69 bits (2765), Expect = 0.000e+0 Identity = 617/1539 (40.09%), Postives = 903/1539 (58.67%), Query Frame = 0
Query: 13 FFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVIL---VNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVG--LALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMV---ASGTVEEWVLLITY---VPIILGLFIAHCWVDIDPR-AAEDLSL----EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNL---PKSPRSMNVTDNVKAFTKQWRKQ------------------AEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSN-EPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSP-HAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYT--------------------------------------SNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADD-LIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
F+D +L +T +P++T C +++LL VPCI +A + +Y R + S L+K L +L V+ F G V G P+ +F L+V V LA L ++ G S L +FW ++C I + +S+++ A G + + T+ ++L I C+ + P +A+++ E A LS L F W + G++ PL+ K+L + RS V V+ + WRKQ ED+++ P S L G LI+ L + LL F++PQ++ +LI+ + + P W GF ++ S++ ++ Y ++ ++ ++ R ++G +Y+K+L ++N +R +VGE+ N MSVDAQR ++ P++ L +PL I++A+YFL+ L + LAG+ + IP+N + ++ QV+Q++ KD+R+KLM+E+L GIKVLKLYAWE F++++ IR E+++++ L F++ SP LVT+ +YV +DP +VL A+K FV+++LFN++R PL P + + VSLKRI +FL+ E+D +V +SP +AI + T TW D + P L +++ +P G+L A+VG VG GKSSL+S+ LGEMEKL G+V ++GS+AYVPQQAWIQN TL++N+LF + + Y + + C L DL +L D+TEIGE GINLSGGQ+QRVSLARAVYSDADI+LLDDPLSAVD+HV K IF V+ EG L KTRVLVTH ++FL + D IIVL +G+V+E G Y LL +F+ FL Y ++PVT V+ ++ L+ + + + VP + P E + E AD L +EEK G V V+W Y +++G + LY S AN WLS W N+A ++ + T LGVY +G++Q L + QA++V+H LL +RSP +FFDT P+GRI+N FS DI VD+V+ + ++ F+ +S +VV+ +STP+F VI+PL ++Y VQRF+ S+Q+KR ESV++S I++HFSET+TG + IRAY + F S +V + + +NRWL + VE +GN VV FAA+FAV+ R +L+PG+ GLS++Y+L + LNWMIRM+ +LE+N VA+ER+ EY+ E+EA W + + WP G V F++Y+ RYR GLDLVL+ + + V EK+GI GRTGAGKSS+TL LFRI+EA KG I IDG ++A +GLH LRS++TIIPQDP+LF+G LR NLDP +S+ +IW AL+ +HL +S GL + SEGGEN SVGQRQL+CLARALLRK++ILVLDEATAA+DL TD+LIQ+TIR +F+ CTV+TIAHRLNTI+D R+ V G +AEF SPA L+A M DAGL
Sbjct: 14 FWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLR-HHCRGYIILSH-----LSKLKMVLGVLLWCVSWADLFYSFHGLVHGR---APAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAI----VPFRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMV---VQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSV--ERKTISPGYAITIHSGTFTWAQD--LPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVI-GPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYAPDEDQGHLEDSWTALEGAEDKEALLIEDTLSNHTDLTDNDPVTYVVQKQFMRQLSALSSDGEGQGRPVPRRHL-GPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWT--NDAMADSRQNNTSLRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVE-GSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIA-ARGIFYGMARDAGL 1526
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|6016599|sp|O88563.1|MRP3_RAT (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=MRP-like protein 2; Short=MLP-2; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1068.14 bits (2761), Expect = 0.000e+0 Identity = 623/1526 (40.83%), Postives = 890/1526 (58.32%), Query Frame = 0
Query: 13 FFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVIL---VNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVG--LALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVE--EWVLLITYVPIILGLFIAHCWVDIDPR-AAEDLSL----EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRP--------FVSLWPILFKNHGWRALIA------LIVALFRV---LLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSP-HAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYT------SNPVTSEVETDELKVLATTTK--------EPPKREVRVP--------SEEVESPEE------TDNLIEET-------ADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
F+D +L T P++T C +++LL VPCI A + Y R +S L++ L +L ++ + F G V GS P+ +F LLV + LA L ++ G S L +FWL +IC I + I + ++ + Y ++L FI C+ + P + E+L E A S L F W L G++ PL+ +L V+ + W+KQ T+ + P + P K RAL+ L+ A F++ L P + + P W GF ++ SS + T+ H + + + A+++R +++G +Y+K+L ++N +R Y+VGEM N MSVDAQR ++ P++ L +PL +++A+YFL+ L ++LAG+ V + IP+N S +K QVQQ++ KD+R+KLM+E+L GIKVLKLYAWE F+ ++ IR E+++++ L A F + +P +VT+ G+YV +D +VL A+K FV+++LFN+++ PL P + + VSLKRI +FLN E+D V +SP AI + T +W D + P L +N+ IP G+L A+VG VG GKSSL+S+ LGEMEKL G V V+GS+AYVPQQAWIQN TL++N+LF Q + Y + + C L DL +L D+TEIGE GINLSGGQ+QRVSLARAVYSDA+I+LLDDPLSAVD+HV K IF QV+ EG L KTRVLVTH ++FL + D IIVL +G++ E G Y +LL +F+ FL Y +N + +E+ +L T EP EVR S E E T +L +E LI+EE G V VYW Y +S+G + LY + V AN WLS W + E H + + T LGVY +G++Q +L ++ QA++++H LL +R+P +FFDT P+GRI+NRFS DI + +V+ + + + ++S IVV+ +STP+F V++PL + Y FVQRF+V S+Q+KR ESV++S IF+HFSET+TG + IRAY + F S A+V T+ +++NRWLG+ VE +GN VV F+A+FAV+ R +L+PG+ GLS++YAL + +LNWMIR L +LE+N +A+ER+ EY+ E+EA W L + + WP G V F++Y+ RYR GL+LVLK + + V+ EK+GI GRTGAGKSS+TL LFRI+EA +G I IDG ++A +GLH LRS++TIIPQDP+LF+G LR NLDP +SD +IW L+ +HL +S GL + SEGG+N SVGQRQL+CLARALLRK+++LVLDEATAA+DL TDDLIQ TIR +FE CTV+TIAHRLNTI+D +R+ V G +AEF SP L+A M DAGL
Sbjct: 14 FWDSNLTVYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHRLGYIVLSC------LSRLKTALGVLLWCISWVDLFYSFHGLVHGSS---PAPVFFITPLLVGITMLLATLLIQYERLRGVRSSGVLIIFWLLCVICAIIPFRSKILLALAEGKILDPFRFTTFYIYFALVLCAFILSCFQEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTKLAILGYRRPLEDSDLWSLSEEDCSHKVVQRLLEAWQKQQTQASGPQTAALEPKIAGEDEVLLKARPKTKKPSFLRALVRTFTSSLLMGACFKLIQDLSPSSTHSCSASSSGLFRPHGPYWWGFLLAGLMFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDELDPQCV--ERKTISPGRAITIHNGTFSWSKD--LPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVI-GPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTEPAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKSVGLCTTLFICLLYAGQNAVAIGANVWLSAWTNDVEEHGQ--QNNTSVRLGVYATLGILQGLLVMLSAFTMVVGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNCVVLFSALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSKTETEAPWVLESN-RAPEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAKDAGL 1521
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|586962516|gb|AHK05646.1| (ATP-binding cassette transporter sub-family C member 1 isoform X6 [Tigriopus japonicus]) HSP 1 Score: 1850.48 bits (4792), Expect = 0.000e+0 Identity = 907/1475 (61.49%), Postives = 1130/1475 (76.61%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGR--ASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTS-PIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVES-PEETDNLIEET----ADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPK-VGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FCRDPFFD++ VWNTTDPN+TQCM+DTLL+G+PC + LI S+IW++YQ R S +G LF AK L+++VN +GQ + GG D+LVPSE+ HY CLL + +A +Q +DK+L +H SPPLFLFWL L+ CE+ KLKIDIQ+ + T E WVLL++Y P+I + C DID A +S ED+AS LSLL FSW DGL+W+G + L LPKSPRS+NV NV+ F WR++ E V+F S RPF+ +W I + R A +VA+ ++LPFV+PQI+KLLI H+DS+E W+G+FYT+VLL S+ +ST+ FH YQQHL ISAIQMR++++GA+Y+KSL+LSN ARR ++VGE+TNYMSVDAQR+V+TFPY M LIM+PLTI++AMYFLF E+ ++SLAGL + I IPIN G K ++LQV QL+AKD RLKLMNE+LMG++VLKLYAWE PFM RI +IR +E+KI+++C RLWAF+NF++ +PILVTI VF +YV +DP+HVLTADKIFV+++LFNL+R PLV FPFTL+E++K+ VSLKRIN +LNA+EI+S NV H D A+E+ + TLTWD + P L +++ IP GSL A+VG VG+GKSSLLS+ LGEME +SG GSIAYVPQQAWIQNM+L+DNILFD+ F T Y +V+R CQLE DLAILK+ D TEIGENGINLSGGQKQRVSLARAVYSDAD+YLLDDPLSAVDAHVGK+IFTQV D+ +G KDKTR+LVTHN++ L K+DNIIV+K G+V E GSYQKLLADG AFSEFL Y AT EP + + VE E+ N I+++ + DLI++E+ + GRV VYW YV S S+FF VV L+ + S + A +NYWLS WAD N+ P+ + + ++LG+YG GVVQLIL+FSREL++ + CA AS+++H+KLL V RSPM+FFDTNPTGRI+NRFSSD+D VDQ +P GLSD +W FD+LS++VV+C STP F VI+PL L+Y+F+QR F+ S+Q+KR ES++KS I+A+FSETITG ASIRAY +Q RF ES+ RVQKC CTFL SANRWLG RVE+LGNL+VFFAAIFA+L+R+ LSPG+AGLSITYAL IMD LNW+IRMLCELETNSVALERI+EYTHN+ EA+W+ P D K + TWP G V F S A RYR GLDLVLKGI ME++ EKIGICGRTGAGKSS TL+LFRI+EA G I IDGQDI+++GLH LRSRITIIPQDPVLFTG+LRFNLDP +HSD +WSAL+HAHLK HIS K GL HEI+EGGENFSVGQRQLICLARALLRKTKIL++DEATAAVDL TDDLIQ+TIRREF+ CTVITIAHRLNTI+DCDRIAVF+ G++AE+ P +LL+ SAL M DAGL
Sbjct: 16 FCRDPFFDVNTVWNTTDPNLTQCMQDTLLIGLPCCVLLITSVIWNLYQYVIEFRHVTSLEERSFGALFFAKLVLNLILIVNAVGQLWNLANLNGGWDQLVPSEIVHYACLLGILFVANVQVIIDKWLLSHTSPPLFLFWLVLIFCEVAKLKIDIQTIVEGHSTWEHWVLLLSYFPVIFVQLVLSCISDIDKTTALFVSPEDRASFLSLLTFSWFDGLIWKGARQILTQDILPKSPRSINVGHNVQDFLNLWRQKVEFLGVNFASFQERPFIGIWSIFIRTQWVRVTFAFLVAIIHLVLPFVNPQILKLLINHVDSDEEAWKGYFYTVVLLISATVSTITFHVYQQHLSISAIQMRSAIIGAIYRKSLKLSNHARRQFTVGEITNYMSVDAQRVVDTFPYTMALIMAPLTIIVAMYFLFLEVGISSLAGLAILLILIPINGIGGKWAERLQVNQLKAKDKRLKLMNEVLMGMRVLKLYAWENPFMDRIKKIRDSEVKILRLCARLWAFMNFTFTGAPILVTIAVFALYVLIDPSHVLTADKIFVSLSLFNLIRIPLVMFPFTLVETIKLIVSLKRINTYLNANEINSANVSHNM-DCESDAVELKDLTLTWDEPES--PSLMNISIQIPKGSLVAVVGEVGSGKSSLLSAILGEMEVVSGSAHAVGSIAYVPQQAWIQNMSLKDNILFDKAFVRTKYDEVVRCCQLESDLAILKNADSTEIGENGINLSGGQKQRVSLARAVYSDADLYLLDDPLSAVDAHVGKSIFTQVFDNQQGLFKDKTRILVTHNISVLSKVDNIIVMKGGRVVEIGSYQKLLADGAAFSEFLNIYAQE--------------ATEKHEPVDDVNQFENSHVEQISEQKINQIQDSTLAESGDLIKDERAMVGRVKWSVYWHYVNSSRISRFFLVVCLHAIGSALLASSNYWLSIWADANQNDPDEANTQIAYFLGIYGAFGVVQLILEFSRELMYFLGCATASQIMHEKLLYHVFRSPMSFFDTNPTGRIINRFSSDVDVVDQRIPQGLSDTMWSIFDSLSIVVVICVSTPSFGYVILPLVLLYYFIQRMFISTSRQVKRLESLSKSPIYANFSETITGTASIRAYGEQIRFNQESENRVQKCAQCTFLIASANRWLGTRVEILGNLIVFFAAIFAILARDTLSPGVAGLSITYALNIMDNLNWLIRMLCELETNSVALERIIEYTHNDQEADWESPNDSKELSQTWPNRGKVEFDSLAIRYRKGLDLVLKGISMEIQGQEKIGICGRTGAGKSSFTLALFRILEADSGEIRIDGQDISKIGLHALRSRITIIPQDPVLFTGDLRFNLDPTGLHSDSSLWSALEHAHLKSHISSFKDGLDHEINEGGENFSVGQRQLICLARALLRKTKILIMDEATAAVDLATDDLIQATIRREFKDCTVITIAHRLNTIMDCDRIAVFNQGEVAEYAPPRDLLSIDNSALSLMAKDAGL 1473
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|586962506|gb|AHK05641.1| (ATP-binding cassette transporter sub-family C member 1 isoform X3 [Tigriopus japonicus]) HSP 1 Score: 1536.55 bits (3977), Expect = 0.000e+0 Identity = 771/1504 (51.26%), Postives = 1046/1504 (69.55%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPL---FLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDK-FLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSL-EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSN-EPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVR---------VPSEEVESPEETDNLI-----EETADD-----------------LIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP-LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC DPFF+ + W+T DPN+TQCMRDT+LVGVPC +FL+ W+I+Q + R G + F+ K TLV++ N + + ++GGS + SE+FHY L + + L+Q +D+ FL A S PLF FW L + IP K +I + + S E+W L+++Y P++L F+ +CW D+ ++L+ ED AS SLL FSWL L+W+G K+PL K LPK P+++ V NV F W K+ V+F + FVS++P+L+K H R L+ + ++ L+ F+SPQI+KLL+ H+ S + W+G+ Y + L S + T +FH Y Q+ + +IQMR+S++G +++K+ RLSN +++ Y+ GE+TNY+SVDAQR+V+T PY+ L +PLTI +A YFL+ EL S AG+ + +PINLF K V++LQ QL+ KD R+KLM+E+L GIKVLKLYAWE PFM+R+ IR EIKI++ RL A INF++ SPILVTI VFG+YV +D + LTA+KIFV+++L N+ R PL+ FP+ LIE +K+ VSLKRIN+FLNA E++S+ V D + +A+E T A+ TW+ +G D I+ +NL IP SL A+VG VG+GKSSLLS+ LGEMEK SG + GSIAYVPQQAWIQNMTL+ NILF+ ++ ++ Y +V+ CQL+ DL ILK D TEIGENGINLSGGQKQRVSLARAVYSDAD+YLLDDPLSAVDA VGK IF +VL + GCL+DKTRVLVTHN+N L ++D+I+V+++GK+AESGSY+KL DG AF+EFL +T + V E+ + ++ + V +P +S EE LI EE D+ L+ EE + G V V+ TY + IG S+F +V L+ + H+ ANYWLSRWAD N P+ ++ YLG Y +G+V++ +F+ E LH +SCA ASK+IH++LL+ VM SPM+FFDTNP GRI+NRFS D+D +DQ +P+ + D +WC D +S+IV++ STP F+ IIPLG+++ QR+++ S+Q+KR ++V+KS + AHFSETITG ASIRAY+QQDRF+ E + R++ C +L VS NRWLG+R+E+LGN++VFFAA+F +L R +LSPG+AGLSI+Y+L IMD L WM+RM+CELETN VALERILEYT N EA W++P +D + WP+EG V K+Y TRYR GLDL L GID+EV++++ IGICGRTGAGKSSL+L+LFR+IEA G I ID DI+ LGLH LRS +TIIPQDP+LFTG++RFNLDP + SD ++W+AL H HLK + +L GL H++SEGG NFS+GQRQLICLARALLRKT ILVLDEATAA+DL TD+LIQ+TIR EF+ CTV+TIAHRLNTI+D D+I V S G++ E+ SPA LL++ S M DAGL
Sbjct: 2 FCPDPFFNSSITWDTDDPNLTQCMRDTVLVGVPCGVFLLLVPFWNIHQFQSYSRRDVFPRIRGNISVRFVLKIVSTLVLIANTIVRI----RNLGGSRTIFGSEIFHYGLLCFTLFVVLVQEFIDRRFLCAIKSLPLFSFWFVLSLASIPGFKYEID-QALESSQAEDWALILSYYPLVLAQFLLNCWSDLGGITDDELAPPEDSASYPSLLTFSWLHRLIWKGFKSPLTLKQLPKPPKTILVATNVLRFLNAWTKKVASMGVNFETEGTRFVSVFPVLWKCHWPRILLCIGLSASHYLIGFISPQILKLLVNHVASQTDQTWKGYLYVVALFLESCVWTFSFHMYCQNASVLSIQMRSSMMGMVFRKAFRLSNSSKKHYTTGEITNYVSVDAQRLVDTMPYLSNLWCAPLTIGLAQYFLYQELGPVSFAGIGTLFLLMPINLFTGKWVERLQADQLRNKDERIKLMSEILGGIKVLKLYAWEKPFMKRLLNIRDNEIKILQFSARLRALINFTFFCSPILVTISVFGLYVLVDCQNTLTAEKIFVSMSLLNMTRYPLIMFPWALIEGIKLIVSLKRINKFLNAKEMNSSLVTKEVIDPN-NAVEFTSASFTWN--EGSDAIIQDINLKIPSRSLVAVVGMVGSGKSSLLSALLGEMEKTSGSIGRVGSIAYVPQQAWIQNMTLKQNILFENDYEASRYHQVLDKCQLKQDLEILKSGDETEIGENGINLSGGQKQRVSLARAVYSDADLYLLDDPLSAVDALVGKNIFDEVLANENGCLRDKTRVLVTHNLNVLPRVDHIVVMRHGKIAESGSYEKLKKDGGAFAEFLENFTFDKVQEEIVSASPSTSVPIRQQSSESNVSPFGSPKFQGIPYVRHDSWEEAKQLIRPGDNEERLDEREPLVQPLESIHSGNETLLMEESSFQGSVKWSVFLTYFKDIGFSKFLLIVILFVTSQSCHSFANYWLSRWADVNHKCPDKSAENILTYLGTYSALGLVEIGTEFAYEFLHFLSCAYASKLIHERLLERVMHSPMSFFDTNPMGRILNRFSVDVDSLDQNIPSMIRDFLWCMCDLVSIIVIITYSTPWFSVTIIPLGVVFMMFQRYYIATSRQLKRLDAVSKSPVLAHFSETITGAASIRAYRQQDRFIEEFETRLETNIKCYYLMVSCNRWLGVRMELLGNVIVFFAALFVILKRSSLSPGVAGLSISYSLNIMDALTWMVRMVCELETNFVALERILEYTDNPQEAPWEVPAIDDNLPQNWPSEGKVCMKAYKTRYREGLDLALNGIDLEVKAHQSIGICGRTGAGKSSLSLALFRVIEACHGTIFIDDVDISTLGLHRLRSCLTIIPQDPILFTGSVRFNLDPTQTSSDFDLWNALGHVHLKPIVENLSEGLDHQVSEGGINFSLGQRQLICLARALLRKTTILVLDEATAAIDLETDNLIQATIREEFKSCTVLTIAHRLNTIMDNDKIVVLSQGRVLEYDSPAALLSDENSTFSDMAKDAGL 1497
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|586962518|gb|AHK05647.1| (ATP-binding cassette transporter sub-family C member 1 isoform X7 [Tigriopus japonicus]) HSP 1 Score: 1374.38 bits (3556), Expect = 0.000e+0 Identity = 722/1522 (47.44%), Postives = 997/1522 (65.51%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIY-------QTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPF----VSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDE-----LKVLATTTKEPPKREVRVP---------------SEEVESPEETD-------------------------NLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC+DPF++ L WNTT+P++TQCM+DTLL GVPC+ FL+ +W IY Q++ R S + +G FL K T LV++ NL+ Q + H D+ SE+F + ++ + L L+ V+K+ H SPP+FLFW LL+ +IP +K ++ V W+L TY P+ L I HCW D A D E AS + + ++W+D L+W G K PL +P P+ + V+ ++ F QW K+ F P V + +LF +G R + ++ L FV P ++KLLI+H+ S+E W+GF Y I++ ++ L ++ H + Q ISA Q+R SL +Y+K+L+LSN AR+ +++GE+TN++S D Q + T PYM + ++P+ I+IAM+FL+ EL + G+ + A+ +P+N + S +KK++ Q++AKD R+KLMNE+L G++VLKLYAWEIPFM RI IRLTE+K++K +++A NF+ S P L+TI FG+Y P +LTADKIFV+IALFN++R +V P+ ++ +K FVSLKRI +FLNA+E+D + + +AIE+T+ + T +++ L +N+ I GSL A+VG VGAGKSSLLS+ LGEMEK GQ+ G++AYVPQQAWIQNMTL++NILF++ F + Y + + C L+ DL IL D TEIGENGINLSGGQKQRVS+ARAVYSD+D+YLLDDPLSAVDAHVGK +F +V S G LKD+TRVLVTHNV+FLD+MD I+V++NG +AE GSY +L AFSEFL QY + EV D L+ ++ P R R+ S ++P D + + A L+++E+ + G+V KVY +Y++ +G LY + + + ++YWLS WAD N A P T +D+T FYLGVY GIG +Q+I+ RE++ ++CA AS +IH +LL V+ SPM+FFDTNP GRIVNRFS+DI VD +P +S + C +V+ ++C S PIF +VI+PL +Y+ +QR ++ ++Q++R ES+ S IFAHF E++ G+ SIRAY+Q++RF+ ES+ RV K ++ V NRWLG+R+E L NLVVFF A+FAVLSR +SPG+ GL+IT++L + LNW+IR +C++ET++VALERILEY+ N EA+W LP D K +P EG + F Y TRYR GLDLVLK + M ++ EKIGICGRTGAGKSSLTL+LFRIIE V G+IL+DG D+ LGLH LRS +TIIPQDPVLFTGN+RFNLDP E ++D +IW AL+HA+LK HIS L GL HE+SEGG+NFSVGQRQL+CLARALLRKTKIL+LDEATAAVDL TDDLIQ+TIR+EF CTV+TIAHRLNTILD DR+AVFS G++ E SP L+ S + + +AGL
Sbjct: 21 FCKDPFYNSSLTWNTTNPDITQCMQDTLLTGVPCLFFLLTEPLWIIYKIYYYSIQSFPISRDS--RNTWGWKFLIKVTLNLVLITNLILQI-WNQSH----DEFYGSEVFRFMAMIGTIVLMLVAMGVEKWNRIHTSPPMFLFWGLLLLVKIPTVKDHVEHLTNDPSDVLYWILAFTYYPVFLLQIIFHCWADHSNMDASDKPPESVASFPATIFYTWIDPLIWAGLKAPLTLDQVPPQPQYVTVSFVIQDFLNQWSKKVSKIEKTFIKDRDPAGEKKVKILDVLFATYGKRFFLIFLLGTVNFTLIFVGPIMLKLLIQHVQSDEEAWKGFAYVILIFVNASLQSLLNHQFLQQTVISAQQIRASLSSMIYRKTLKLSNLARKKFTMGEITNFISTDIQTLGMTIPYMNNVWVAPMKIIIAMFFLYEELKSVAFIGVAIMAVLLPLNYWSSVIIKKMRKNQMEAKDGRIKLMNEVLKGMRVLKLYAWEIPFMSRINAIRLTEVKLMKSLAKVYAISNFTLNSGPTLITIACFGLYTVFQPGEILTADKIFVSIALFNIIRMSMVMLPWAIVALLKAFVSLKRIADFLNANELDP-EAVGKETEHEENAIEITKGSFT-WTEEEEQTTLKDINVQIRKGSLVAVVGVVGAGKSSLLSAILGEMEKTDGQINQSGTLAYVPQQAWIQNMTLKNNILFEKPFETGRYKRTLEACALKDDLDILISGDETEIGENGINLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDAHVGKHLFDKVFSSKSGILKDRTRVLVTHNVSFLDQMDLILVMRNGTIAERGSYSQLKESKGAFSEFLEQYANQATKEEVTEDHEKNKHLQAKPIKARQIPPRTRRMSQTLSCSPASPFIKYLSTSADAPLPDDILAEEEEAILEETIEESAVSSRRGSKVNDPLAGRLVDDEEAMIGKVNWKVYLSYMKDLGNIISVISFLLYMVGQGLESGSSYWLSFWADSNGADPATANDKTPFYLGVYSGIGALQIIIMIVREIVLFIACADASNLIHARLLSKVVSSPMSFFDTNPIGRIVNRFSADIGTVDDGIPFQISLLFECFTSIATVLALICYSLPIFMTVILPLAFMYYGIQRCYISTTRQLQRIESIVISPIFAHFGESLNGVQSIRAYKQEERFILESEKRVDKGVQLHYMCVMMNRWLGVRIEFLANLVVFFVALFAVLSRGTISPGLTGLAITFSLNVTGMLNWLIRAVCDMETDAVALERILEYSENPQEADWSLPEDDKFCD-FPMEGQIEFSKYETRYREGLDLVLKDVSMRIQPKEKIGICGRTGAGKSSLTLALFRIIEPVSGKILVDGIDVNTLGLHKLRSGLTIIPQDPVLFTGNVRFNLDPTEENTDTQIWQALEHANLKAHISSLTNGLDHEVSEGGDNFSVGQRQLLCLARALLRKTKILILDEATAAVDLETDDLIQATIRKEFADCTVLTIAHRLNTILDSDRVAVFSEGKLVELDSPQSLMDKHDSVFRGLAKNAGL 1532
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1133439954|ref|XP_019876350.1| (PREDICTED: LOW QUALITY PROTEIN: multidrug resistance-associated protein 1-like [Aethina tumida]) HSP 1 Score: 1251.11 bits (3236), Expect = 0.000e+0 Identity = 683/1529 (44.67%), Postives = 960/1529 (62.79%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAV----DKFLGAHISPPLFLFWLALLICEIPKLKIDI-QSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLE-----DKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKA----FTKQWRK-----------------QAEDKLVDF--TSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTS-----------NPVTSEVETDELKVLATTTKEPP---------KREVRVPS-----EEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALA---NYWLSRWADHNE-AHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMA-FFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+D +L WNTTDP++T+C T+LV PC S++ Y T ++ R + L ++K T + V + + D VP + P + + L+ L +AV +K G S FLFWL L +C + + +I Q+++ ++V + Y P++L + + +C+ D P+ + +E + AS S L+F+W D L W G K PL+ ++L MN D+ K F K W K + + VDF +S +P S+ P L ++ G + L + LL FVSP I+ LLI + + W+G+ Y ++LL ++ + T+ Y + I +++R +L+ +Y+K+L++SN AR+ +VGE+ N M+VDAQ+ V+ Y+ + +PL I ++MYFL+ EL + LAGL + I IP+N F + VK LQ++Q++ KD R+KLMNE+L GIKVLKLYAWE F +++ +IR EIK++K + A +F + +P LV++ F YV +D ++VL A+K +V+I+LFN++R PL P + V+ +VS+KRIN+FLN E+D NV H N++ P E +W G +P+L +N+ + GSL A+VGTVG GKSSL+ + LGEMEK SG+V GSIAYV QQAWIQN TLRDNILF ++F Y V++ C L+PD +L D+TEIGE GINLSGGQKQRVSLARAVY+DA+IYLLDDPLSAVD+HVGK IF QV+ T G L KTRVLVTH + +L + D I+V+KNG+++ESG+YQ+LL +F+EFL+Q+ S + V E++T E K + + E +R+ + S + +S E++ ++ ++ + LIE EK+ G V +VY Y++SIG FF L V + N WL RWAD + A+ + + YLGVYG +G+ Q+I F L + A+K +H LL+ +M+ P F+D P GRI+NRFS D+D +D V+P L I C F + +VV+ +TP+F VIIP+GL+Y+F+QRF+V S+Q+KR ESV++S I++HF E+ITG +IRA+ Q++RF+ ES+ +V + C + ++ +NRWL +R+E++GNL++FFAA+F VL ++NL PG+ GLS+TYAL I TLNW++RM ++ETN VA+ERI EY EA W++P WP GAV FK+YA RYR GLDLVLKG+D V EKIGI GRTGAGKSSLTL+LFRIIEAV+G I IDG I++LGLHTLRSR+TIIPQD VLF+G+LR NLDP + HSD E+W +L+HAHLK + L G+ H+++EGGEN SVGQRQLICLARALLRKTK+LVLDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V GQI EF SPA LL N S +M DAGL
Sbjct: 9 FCGSDFWDYNLSWNTTDPDLTKCFERTVLVWFPCAFLWTFSILEIYYITNSKKR----DIPWNWLNVSKLVVTAALCVLSATDLVTSVKNAKSEDGSVPKVDIYTPVIKI---LSFLLSAVLLVFNKKHGLQTSGLQFLFWLLLGLCGAVQFRTEIRQAQVQVPEPYYDYVSYLIYYPLVLIMLLLNCFADKSPKHTQYAKVERPCPEEGASFPSRLLFAWFDTLAWLGFKKPLEAQDL----WDMNPQDSAKEVVPLFEKYWHKTLQKCESSSSPHTRASFKPDSASVDFVNSSKKKP-ASILPALVESFGPTFFFGASLKLVQDLLTFVSPIILGLLITFVKEQQETWKGYMYAVLLLATATVQTIILSQYFNRMFIVGMRIRTALVATIYKKALKISNAARKQTTVGEIVNLMAVDAQKFVDLTAYLNMIWSAPLQIFLSMYFLWNELGPSVLAGLAIMIILIPVNGFIANKVKVLQIKQMKNKDERVKLMNEILSGIKVLKLYAWEPSFEKQVLQIRAKEIKVLKEAAYMNAGTSFIWSCAPFLVSLVTFATYVLVDESNVLDANKAYVSISLFNILRFPLSMLPMMISNMVQTWVSVKRINKFLNEEELDPNNVTHDQNEVDPIIFE--NGNFSW----GDEPVLKNINIRLTKGSLNAVVGTVGCGKSSLIYASLGEMEKKSGRVNTVGSIAYVSQQAWIQNATLRDNILFGKKFDQKIYDNVVKACALKPDFDMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYADAEIYLLDDPLSAVDSHVGKHIFEQVIGPT-GLLGKKTRVLVTHGITYLPQTDKILVMKNGEISESGTYQELLNKKGSFAEFLLQHASEGPAEDLDEIESQVPDEIKT-EFKRMRSHVSESEGSEKANGSLQRQRSIDSSGKERQRSKSIEDSKSVSKKEGEKLIEAEKSETGSVSWQVYKYYLKSIG---FFLTAATILLNMVFQGFSIGSNVWLGRWADDKDLANGTQNTQKRDMYLGVYGALGIGQVIAIFLSVLALYVGTLNAAKSLHRLLLENIMKVPTTTFYDVTPVGRILNRFSKDVDTLDNVLPMTLRGWITCFFSVIGTLVVISYTTPLFIIVIIPIGLLYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESITGAQAIRAFGQEERFITESERKVDQNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFGVLGKDNL-PGLVGLSVTYALQITQTLNWLVRMTSDVETNIVAVERIKEYGEATQEAAWEVP-SKNPSSLWPEVGAVEFKNYAVRYRPGLDLVLKGVDFSVNGGEKIGIVGRTGAGKSSLTLALFRIIEAVQGDIYIDGVKISELGLHTLRSRLTIIPQDAVLFSGSLRMNLDPFDKHSDDEVWRSLEHAHLKDFVKGLPSGIQHQVTEGGENLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQRTIRTEFKNCTVLTIAHRLNTIMDSDRVLVLDKGQIVEFDSPATLLLNSKSIFYSMCKDAGL 1512
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1080053916|ref|XP_018568578.1| (multidrug resistance-associated protein 1 isoform X9 [Anoplophora glabripennis]) HSP 1 Score: 1242.25 bits (3213), Expect = 0.000e+0 Identity = 680/1528 (44.50%), Postives = 954/1528 (62.43%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFV-GLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDI---QSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPR-----AAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWR-----------------KQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYT----------------------SNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNL-------IEETADD-----LIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHN--EAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F++L+L WNT DP+ T+C T+LV +PC S + Y ++ R + + L ++K T ++ + L + SD +V S + P + +F L+ L ++ G S LFLFWL L +C + + +I Q + G+ ++ + Y P++L +F+ +C+ D PR +E E+ AS LS L+F+W D L W G + PL+ +L + + V F K W+ K D + S + S+ P L K+ G ++ L + +L FVSPQI+ +I ++ + W+G+F+T +L ++ + T+ Y + I +++R +L+ +Y+KSL++SN AR+ +VGE+ N MSVDAQ+ +E ++ + +PL I++++YFL+ EL + LAGL V I IP+N F + VK LQ++Q++ KD R+KLMNE+L GIKVLKLYAWE F ++ +IR EIK++K L A +F + +P LV++ F +V +D +VL A+K +V+I+LFN++R P+ P + V+ +VS+KRIN F+N+ E+D NV H + + P IE + T +W G DPIL +N+ + +LTA+VGTVG+GKSSL+S+FLGEM+K+SG+V G IAYV QQAWIQN TL+DNILF ++F Y KVI C L+ D +L D+TEIGE GINLSGGQKQRVSLARAVYSDADIY LDDPLSAVD+HVGK IF +V+ +G L+ KT+VLVTH + +L + D+IIV+K+G+V+ESG+YQ+LL AF+EFL+Q+ S VT + +V + ++ R + + +S + TD IEE+ +D LIE EK G V VY Y++SIG F + L + +N WL WA+ + + + R YLGVYG +G+ Q + EL + C A+K +H L GV RSPM FFDT P GRI++RFS DI+ VD +P +SD ++C F+ + I V+ +TP+F VI+P+GL+Y+F+QRF+V S+Q+KR ESV++S I++HF ET+TG+ +IRAY QQ+RF+ ES+ +V C + +V +NRWL +R+E++GNL++ FA++FAVL +E P + GLSITYAL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G+V F +YA RYR GLDLVLKG+D ++ EK+GI GRTGAGKSSLTLSLFRIIEA +G+I IDG +IA+LGLHTLRSR+TIIPQD VLF+G LR NLDP + HSD E+W AL+HAHLK +S L L HE+SEGGEN SVGQRQLICLARALLRKTK+LVLDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTI+D DR+ V GQI EF +PA LLANP + M DAGL
Sbjct: 9 FCGGEFWNLNLTWNTNDPDFTKCFEKTVLVWIPCFFLWTFSSLEVYYLIKSKRR----NIPWNWLNISKLVVTGILSILCLSDLV-NAFKSADSDNVVYSVDIYSPLIKLFTFALSALLVVYNRKHGMPSSGLLFLFWLLLGVCGAVQFRSEIRRAQRSEIPPGSKYFYISYLIYYPLVLLMFLLNCFADKPPRESKYPKSERPCPEENASFLSRLLFTWFDSLAWTGFRKPLEATDLWDMKPEDSAKEIVPLFEKHWQNTLDKSGSYSPTQNAQFKSDVDHVAFVNSKKKKEASVLPALVKSFGPTFAFGALLKLMQDILTFVSPQILGYIITYVRKGQYEWRGYFFTALLFITATIQTLLLAQYFNRMFIVGMRIRTALISTIYRKSLKISNSARKETTVGEIVNLMSVDAQKFIELTAFLNMIWSAPLQIILSLYFLWYELGPSVLAGLAVMIILIPVNGFIANKVKTLQIKQMKNKDERVKLMNEILSGIKVLKLYAWEPSFENQVLKIRNKEIKVLKSAAYLNAGTSFIWSCAPFLVSLVTFATFVLVDENNVLDANKAYVSISLFNILRFPMSMLPMMISNLVQTYVSVKRINRFMNSEELDPNNVTHDSFEADPLIIE--KGTFSW----GDDPILKNINIRLKKQTLTAVVGTVGSGKSSLISAFLGEMDKVSGRVNTVGRIAYVSQQAWIQNATLKDNILFGKKFDKVLYNKVIEMCALKADFEMLPGGDQTEIGEKGINLSGGQKQRVSLARAVYSDADIYFLDDPLSAVDSHVGKHIFDKVI-GPKGMLRYKTKVLVTHGITYLPQTDSIIVIKDGEVSESGTYQELLDKKGAFAEFLLQHITEDVDTDDDLDEIKDQLVGTALSEEVTRRLSRHRSRVSESHSECGSDRILNGSLQRQKSSDSTDKSLRRRAGSIEESKNDSPKGKLIEIEKAETGSVSWDVYKHYLKSIGLFLTFATILLNMVFQGFSIGSNVWLGVWANDSSLNVNGTVNTARRDLYLGVYGALGIGQAVTSVFSELAPGLGCVAAAKGLHQLLTSGVFRSPMTFFDTTPLGRILSRFSKDIEVVDNSLPWYVSDGVYCFFEVIGTIAVISYTTPLFMLVIVPIGLLYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETVTGVQAIRAYGQQERFISESEYKVDLNQVCYYPSVISNRWLAVRLEMIGNLIILFASLFAVLGKEQ-DPSLVGLSITYALQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKNPSSAWPEHGSVEFNNYAVRYRPGLDLVLKGVDFHIKGGEKVGIVGRTGAGKSSLTLSLFRIIEAAQGQICIDGVNIAELGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWRALEHAHLKVFVSGLAAALNHEVSEGGENLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQTTIRTEFKTCTVLTIAHRLNTIMDSDRVIVLDKGQIVEFDTPANLLANPNTIFHGMCRDAGL 1522
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|642933793|ref|XP_008197317.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X4 [Tribolium castaneum]) HSP 1 Score: 1241.48 bits (3211), Expect = 0.000e+0 Identity = 686/1533 (44.75%), Postives = 954/1533 (62.23%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCL-LVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEE-------WVLLITYVPIILGLFIAHCWVDIDPRAAEDLSL-----EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRK--------------QAEDKL----VDF-TSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTT---KEPPKREVRVPSEEVESPEET-------------------------DNLIEET----ADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWA--DHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSR-ENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F++ L W+T DP++T+C T+LV VPC S + Y ++ R + L ++K T V+ V + S+ V + P + L+ GL+ + ++ G S FLFWL+L IC Q R G+ EE ++ + Y P++L + +C+ D PR +E L E+ +S LS L+FSW D L W+G + PL +L + ++ V F K W++ +A KL VD S + S+ P L K G + ++ L + LL FVSP I+ LLI+ + +NE W+GF Y L ++ + T+ Y + + +++R +L+ A+Y+K+LR+SNKAR+ +VGE+ N MSVDAQ+ ++ Y+ + +PL I++A+YFL+ L A LAGL V I IP+N + + VK LQ++Q++ KD R+KLMNE+L GIKVLKLYAWE F ++I +IR EI+++K + A +F + +P LV++ FG YV +D ++L A K FV+++LFN++R PL P + V+ VS++RIN+F+NA E+D T+V H +N+ +P IE WD + +L +N+ I SL A+VG+VG+GKSSLLS+FLGEM+K SG+V G+IAYV QQAWIQN TLRDNILF + F + Y KV+ C L PD A+L D+TEIGE GINLSGGQKQRVSLARAVY+++DIY LDDPLSAVD+HVGK IF +V+ EG L+ KTRVLVTH + +L + D IIVLK+G+V+E G+YQ+LL AFSEFL+Q+ + E E D LK + T +E K+ R S ES ET + +EE + LIE EK G V VY Y++SIG + L L +N WL WA D T + + FYLG+YG +G+ Q I+ +L + C AS +H +L+GV+R+PM FFDT P GRI+ RFS D++ +D +P G++D ++C F+ L +VV+ STPIF +VI+P+G++Y+F+QRF+V S+Q+KR ESV++S I++HF ETITG+ +IRA+++QDRF+ ES+ RV C + ++ +NRWL +R+E++GNL++FFAA+F+VL R E+ + G+ GLS+TY+L I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G V F YA RYR GLDLVLKG++ + EK+GI GRTGAGKSSLTL+LFRIIEA +G ILIDG +IA LGLHTLRSR+TIIPQD VLF+G LR NLDP + HSD E+W AL+HAHLK + L GL+HE++EGGEN SVGQRQLICL+RALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V +G+I EF SP+ LL S +M DAGL
Sbjct: 9 FCGSEFWNSTLTWHTNDPDLTKCFERTVLVWVPCAFLWTFSSLEVYYILHSKRR----DIPWNWLNVSKLLGTAVLFVLTVTDLVTAVNSASSSESDVYKVDIYTPVIKLLSFGLSAVLLVYNRKYGLCTSGLQFLFWLSLAICGA------FQYRTELRGSQEEIPESRYSYISYLIYYPVVLVMLFLNCFADRSPRRSEYPKLKNPCPEENSSFLSRLLFSWFDPLAWRGFRRPLVDSDLWDMKPEDSASEVVPTFEKHWKRILQKCESNSPTRQTRASYKLDSARVDIVNSSTKKQASILPALVKAFGPTFIFGALLKLIQDLLTFVSPHILNLLIQFVKNNEEQWKGFLYAGALFVTATIQTIVLSQYFNRMFVVGMRIRTALVSAIYKKALRVSNKARKESTVGEIVNLMSVDAQKFIDLTAYINMIWSAPLQIILALYFLWNILGPAVLAGLAVMIILIPVNGYIANKVKVLQIKQMKNKDERVKLMNEVLSGIKVLKLYAWEPSFEKQILKIRTKEIQVLKEAAYMNAGTSFIWSCAPFLVSLVSFGTYVMVDEHNILDASKAFVSVSLFNILRFPLSMLPMMISNLVQAMVSIQRINKFMNAEELDPTSVTHDSNESAPLVIE--NGCFNWDEEQ----VLKNINIRIEKKSLCAVVGSVGSGKSSLLSAFLGEMDKTSGRVNTVGTIAYVSQQAWIQNATLRDNILFGKSFDKSLYDKVVEACALNPDFAMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYANSDIYFLDDPLSAVDSHVGKHIFDKVI-GPEGLLRHKTRVLVTHGITYLPQTDKIIVLKDGEVSEGGTYQELLDKKGAFSEFLLQHINEVEEDEEELDVLKSQLSGTAVSEEINKKLSRHRSRVSESVSETGSDQTSLSLQRQKSVESADKSLRHRSSSVEEAKKVKGEKLIEVEKAETGSVKWIVYKHYLKSIGVFLTVATILLNMLFQGFSIGSNVWLGVWADDDTVVVDNVTDTGKRDFYLGIYGALGIGQAIMSLFADLAPQLGCCYASIALHQVMLRGVLRAPMLFFDTTPLGRILGRFSRDVETMDSSLPWGMTDGVYCLFEVLGTLVVISVSTPIFIAVIVPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETITGVQAIRAFREQDRFIKESEHRVDVNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFSVLGRDESQNAGLVGLSVTYSLQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKAPSPQWPENGTVQFNKYAVRYRPGLDLVLKGVNFSINGGEKVGIVGRTGAGKSSLTLALFRIIEAAEGEILIDGVNIADLGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWKALEHAHLKSFVKGLTAGLHHEVTEGGENLSVGQRQLICLSRALLRKTKVLILDEATAAVDLETDDLIQKTIRSEFKNCTVLTIAHRLNTIMDSDRVVVLDNGRIVEFDSPSNLLKQQQSIFYSMCKDAGL 1523
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|749744031|ref|XP_011154501.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X6 [Harpegnathos saltator]) HSP 1 Score: 1234.94 bits (3194), Expect = 0.000e+0 Identity = 684/1546 (44.24%), Postives = 963/1546 (62.29%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAK--FTFTLVIL-VNLLGQFCYTSGH--VGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLE-----DKASCLSLLVFSWLDGLLWQGHKTPLKWKNL-PKSPRSMNVTDNVKAFTKQWRK--QAEDKL-------------VDFTSP-IRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVT------SEVETDELKVLATTT---KEPPKREVRVPSEEVESPEET-----------------------------DNLIEE--------TADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSD--RTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSR--ENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP--LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+D +L W T +P+VT C T+L+ VPCI I S + + Y ++ R + Y LF+ K T L+IL + LG Y S + V D P + ++ F+ ++L K+ G S LFLFW L +C + + I + + V + Y PI+L LF+ + VD +P+ +E ++E AS S L+F+W D L W+G + PL+ +L +P M + + V F K W K Q D++ VDF S + S+ P + K G L + L + ++ F+SPQ++++LI + + EP+W+G+FY ++L ++ L T+ Y + + +++R +L+ A+Y+K+LR+SN AR+ ++GE+ N MSVDAQR ++ Y+ + +PL I++A+YFL+ L A LAGL V I IP+N + VK LQ++Q+++KD R+KLMNE+L GIKVLKLYAWE F ++I +IR EI+++K L A +F + +P LV++ F YV +D +VL + FV+++LFN++R PL P + V+ +VS+KRIN+F+N ++D NV H ++ PHA+ + WD + PIL +N+ + G L A+VGTVG+GKSSLLS+ LGEM+KLSG+V +GSIAYV QQ WIQN TL+DN+LF + + + Y +VI C L PDL IL D+TEIGE GINLSGGQKQRV+LARAVY+D+D Y LDDPLSAVD+HVGK IF V+ G LK KTRVLVTH + +L ++DNIIVLK+G++ E G+Y++LL AF++FL+Q+ SE + E+K +T E ++ R S + ES E+ +N I+E T + LIE EK G V KVY Y+ SIG + + + +N WLS W+D N P D R YLGVYG +G+ Q + F +L + C A++ +H +L+ VMR+P+ FFDT P GRI++RF+ D+D +D +P +SD I+C F+ ++ + V+ STPIF +VI+P+G +Y+F+QRF+V S+Q+KR ESV++S I++HFSE++TG + IRAY Q++F+HES++RV C + ++ ANRWL +R+E++GNL++FFAA+FAVL R +++S GI GLS++YAL I TLNW++RM ++ETN VA+ERI EY EA W PK WP+ G V F+++ RYR GLDLVL GI V +EKIGI GRTGAGKSSLTL+LFRIIEA G ILID DI++LGLH LRS++TIIPQDPVLF+G LR NLDP + H+D E+W AL+HAHLK + +L L HE+SEGGEN SVGQRQLICLARALLRKTK+L+LDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTILD D++ V G I E+ SP LL NPTS+ +M DAGL
Sbjct: 9 FCGTEFWDANLTWYTNNPDVTVCFEKTILIWVPCIFLWIFSSMEAYYILHSKRR----NVPYTWLFIIKQVLTIALIILSIVDLGMAIYESTYREVYSVDYCTP-----FIKIITFILASILMIYNRKY-GMRTSGLLFLFWFILALCGCVQFRTFINKLIDREKSTYPIVSYMIYYPIVLLLFVLNFLVDAEPKFSEYPTVESPCPEQSASYPSRLLFAWFDALAWKGFRKPLEASDLWSMNPEDMAM-EIVPKFDKYWDKNLQKTDEVESAKASFRKASGQVDFNSGRKKKIASILPPICKAFGATFLFGAFLKLVQDIMTFISPQLLRVLIAFVKEKEEPLWKGYFYAVLLFLTATLQTLVLSQYFHRMFLVGLRIRTALIAAIYRKALRMSNAARKESTLGEIVNLMSVDAQRFMDLTAYINMIWSAPLQIVLALYFLWEILGPAVLAGLAVMIILIPVNALIANKVKTLQIRQMKSKDERVKLMNEVLNGIKVLKLYAWEPSFEQQILKIRAKEIQVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLIDEKNVLNSSTAFVSLSLFNVLRFPLSMLPMMISNIVQAYVSVKRINKFMNMDDLDPNNVQHDPSE--PHALLIENGNFCWDMEHVDRPILQNINMHVEQGQLVAVVGTVGSGKSSLLSALLGEMDKLSGKVNTKGSIAYVSQQPWIQNATLQDNVLFGKALNKSVYNRVIEACALSPDLKILPAGDQTEIGEKGINLSGGQKQRVALARAVYNDSDNYFLDDPLSAVDSHVGKHIFENVI-GPGGLLKKKTRVLVTHGITYLPEVDNIIVLKDGEITECGTYKQLLEKRGAFADFLVQHLQEVGNLHVDDGSEADLREIKQQLESTMGADELQQKLTRARSRKSESLSESGSITDRRSLNGSLKRQYSTESQQSANYIHNNSIKEKEATKTNNTGEKLIEVEKAETGSVKWKVYSHYLVSIGLFLSVATIVMNAIFQAFSIGSNVWLSVWSDDNMTTPNGTIDKGRQDMYLGVYGALGIGQAMTSFFCDLAPQLGCWLAARQMHIVMLRAVMRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPPQISDTIYCLFEVIATLFVISYSTPIFIAVILPIGALYYFIQRFYVASSRQLKRLESVSRSPIYSHFSESVTGASIIRAYGVQEQFIHESESRVDINQVCYYPSIIANRWLAVRLEMVGNLIIFFAALFAVLGRDSQDMSAGIVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGETTQEASWKNSEYTPPK---EWPSNGRVDFRNFKVRYREGLDLVLHGISFSVLGSEKIGIVGRTGAGKSSLTLALFRIIEAASGEILIDDIDISKLGLHDLRSKLTIIPQDPVLFSGTLRMNLDPFDNHTDDEVWRALEHAHLKSFVKNLPSSLLHEVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRHEFKDCTVLTIAHRLNTILDSDKVIVLDKGLIVEYDSPDTLLRNPTSSFYSMAKDAGL 1537
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1126581818|ref|XP_019701148.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X3 [Harpegnathos saltator]) HSP 1 Score: 1234.17 bits (3192), Expect = 0.000e+0 Identity = 685/1553 (44.11%), Postives = 963/1553 (62.01%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAK--FTFTLVIL-VNLLGQFCYTSGH--VGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLE-----DKASCLSLLVFSWLDGLLWQGHKTPLKWKNL-PKSPRSMNVTDNVKAFTKQWRK--QAEDKLV--------------------DFTSP-IRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVT------SEVETDELKVLATTT---KEPPKREVRVPSEEVESPEET-----------------------------DNLIEE--------TADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSD--RTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSR--ENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP--LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+D +L W T +P+VT C T+L+ VPCI I S + + Y ++ R + Y LF+ K T L+IL + LG Y S + V D P + ++ F+ ++L K+ G S LFLFW L +C + + I + + V + Y PI+L LF+ + VD +P+ +E ++E AS S L+F+W D L W+G + PL+ +L +P M + + V F K W K Q D+LV DF S + S+ P + K G L + L + ++ F+SPQ++++LI + + EP+W+G+FY ++L ++ L T+ Y + + +++R +L+ A+Y+K+LR+SN AR+ ++GE+ N MSVDAQR ++ Y+ + +PL I++A+YFL+ L A LAGL V I IP+N + VK LQ++Q+++KD R+KLMNE+L GIKVLKLYAWE F ++I +IR EI+++K L A +F + +P LV++ F YV +D +VL + FV+++LFN++R PL P + V+ +VS+KRIN+F+N ++D NV H ++ PHA+ + WD + PIL +N+ + G L A+VGTVG+GKSSLLS+ LGEM+KLSG+V +GSIAYV QQ WIQN TL+DN+LF + + + Y +VI C L PDL IL D+TEIGE GINLSGGQKQRV+LARAVY+D+D Y LDDPLSAVD+HVGK IF V+ G LK KTRVLVTH + +L ++DNIIVLK+G++ E G+Y++LL AF++FL+Q+ SE + E+K +T E ++ R S + ES E+ +N I+E T + LIE EK G V KVY Y+ SIG + + + +N WLS W+D N P D R YLGVYG +G+ Q + F +L + C A++ +H +L+ VMR+P+ FFDT P GRI++RF+ D+D +D +P +SD I+C F+ ++ + V+ STPIF +VI+P+G +Y+F+QRF+V S+Q+KR ESV++S I++HFSE++TG + IRAY Q++F+HES++RV C + ++ ANRWL +R+E++GNL++FFAA+FAVL R +++S GI GLS++YAL I TLNW++RM ++ETN VA+ERI EY EA W PK WP+ G V F+++ RYR GLDLVL GI V +EKIGI GRTGAGKSSLTL+LFRIIEA G ILID DI++LGLH LRS++TIIPQDPVLF+G LR NLDP + H+D E+W AL+HAHLK + +L L HE+SEGGEN SVGQRQLICLARALLRKTK+L+LDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTILD D++ V G I E+ SP LL NPTS+ +M DAGL
Sbjct: 9 FCGTEFWDANLTWYTNNPDVTVCFEKTILIWVPCIFLWIFSSMEAYYILHSKRR----NVPYTWLFIIKQVLTIALIILSIVDLGMAIYESTYREVYSVDYCTP-----FIKIITFILASILMIYNRKY-GMRTSGLLFLFWFILALCGCVQFRTFINKLIDREKSTYPIVSYMIYYPIVLLLFVLNFLVDAEPKFSEYPTVESPCPEQSASYPSRLLFAWFDALAWKGFRKPLEASDLWSMNPEDMAM-EIVPKFDKYWDKNLQKTDELVWTYLRVESAKASFRKASGQVDFNSGRKKKIASILPPICKAFGATFLFGAFLKLVQDIMTFISPQLLRVLIAFVKEKEEPLWKGYFYAVLLFLTATLQTLVLSQYFHRMFLVGLRIRTALIAAIYRKALRMSNAARKESTLGEIVNLMSVDAQRFMDLTAYINMIWSAPLQIVLALYFLWEILGPAVLAGLAVMIILIPVNALIANKVKTLQIRQMKSKDERVKLMNEVLNGIKVLKLYAWEPSFEQQILKIRAKEIQVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLIDEKNVLNSSTAFVSLSLFNVLRFPLSMLPMMISNIVQAYVSVKRINKFMNMDDLDPNNVQHDPSE--PHALLIENGNFCWDMEHVDRPILQNINMHVEQGQLVAVVGTVGSGKSSLLSALLGEMDKLSGKVNTKGSIAYVSQQPWIQNATLQDNVLFGKALNKSVYNRVIEACALSPDLKILPAGDQTEIGEKGINLSGGQKQRVALARAVYNDSDNYFLDDPLSAVDSHVGKHIFENVI-GPGGLLKKKTRVLVTHGITYLPEVDNIIVLKDGEITECGTYKQLLEKRGAFADFLVQHLQEVGNLHVDDGSEADLREIKQQLESTMGADELQQKLTRARSRKSESLSESGSITDRRSLNGSLKRQYSTESQQSANYIHNNSIKEKEATKTNNTGEKLIEVEKAETGSVKWKVYSHYLVSIGLFLSVATIVMNAIFQAFSIGSNVWLSVWSDDNMTTPNGTIDKGRQDMYLGVYGALGIGQAMTSFFCDLAPQLGCWLAARQMHIVMLRAVMRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPPQISDTIYCLFEVIATLFVISYSTPIFIAVILPIGALYYFIQRFYVASSRQLKRLESVSRSPIYSHFSESVTGASIIRAYGVQEQFIHESESRVDINQVCYYPSIIANRWLAVRLEMVGNLIIFFAALFAVLGRDSQDMSAGIVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGETTQEASWKNSEYTPPK---EWPSNGRVDFRNFKVRYREGLDLVLHGISFSVLGSEKIGIVGRTGAGKSSLTLALFRIIEAASGEILIDDIDISKLGLHDLRSKLTIIPQDPVLFSGTLRMNLDPFDNHTDDEVWRALEHAHLKSFVKNLPSSLLHEVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRHEFKDCTVLTIAHRLNTILDSDKVIVLDKGLIVEYDSPDTLLRNPTSSFYSMAKDAGL 1544
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1080053910|ref|XP_018568575.1| (multidrug resistance-associated protein 1 isoform X6 [Anoplophora glabripennis]) HSP 1 Score: 1233.01 bits (3189), Expect = 0.000e+0 Identity = 680/1537 (44.24%), Postives = 958/1537 (62.33%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFV-GLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDI---QSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPR-----AAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWR-----------------KQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSE--------VETDELK---VLATTTKEPPKREVRVPSEEVESPEE--TDNL------------------------IEETADD-----LIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHN--EAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSP-MAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F++L+L WNT DP+ T+C T+LV +PC S + Y ++ R + + L ++K T ++ + L + SD +V S + P + +F L+ L ++ G S LFLFWL L +C + + +I Q + G+ ++ + Y P++L +F+ +C+ D PR +E E+ AS LS L+F+W D L W G + PL+ +L + + V F K W+ K D + S + S+ P L K+ G ++ L + +L FVSPQI+ +I ++ + W+G+F+T +L ++ + T+ Y + I +++R +L+ +Y+KSL++SN AR+ +VGE+ N MSVDAQ+ +E ++ + +PL I++++YFL+ EL + LAGL V I IP+N F + VK LQ++Q++ KD R+KLMNE+L GIKVLKLYAWE F ++ +IR EIK++K L A +F + +P LV++ F +V +D +VL A+K +V+I+LFN++R P+ P + V+ +VS+KRIN F+N+ E+D NV H + + P IE + T +W G DPIL +N+ + +LTA+VGTVG+GKSSL+S+FLGEM+K+SG+V G IAYV QQAWIQN TL+DNILF ++F Y KVI C L+ D +L D+TEIGE GINLSGGQKQRVSLARAVYSDADIY LDDPLSAVD+HVGK IF +V+ +G L+ KT+VLVTH + +L + D+IIV+K+G+V+ESG+YQ+LL AF+EFL+Q+ + V ++ + DE+K V ++E +R R S ES E +D + IEE+ +D LIE EK G V VY Y++SIG F + L + +N WL WA+ + + + R YLGVYG +G+ Q+I+ F L + A++++H+ +L +MR P F+D P GRI+NRFS DID +D V+P L I C + + I V+ +TP+F VI+P+GL+Y+F+QRF+V S+Q+KR ESV++S I++HF ET+TG+ +IRAY QQ+RF+ ES+ +V C + +V +NRWL +R+E++GNL++ FA++FAVL +E P + GLSITYAL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G+V F +YA RYR GLDLVLKG+D ++ EK+GI GRTGAGKSSLTLSLFRIIEA +G+I IDG +IA+LGLHTLRSR+TIIPQD VLF+G LR NLDP + HSD E+W AL+HAHLK +S L L HE+SEGGEN SVGQRQLICLARALLRKTK+LVLDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTI+D DR+ V GQI EF +PA LLANP + M DAGL
Sbjct: 9 FCGGEFWNLNLTWNTNDPDFTKCFEKTVLVWIPCFFLWTFSSLEVYYLIKSKRR----NIPWNWLNISKLVVTGILSILCLSDLV-NAFKSADSDNVVYSVDIYSPLIKLFTFALSALLVVYNRKHGMPSSGLLFLFWLLLGVCGAVQFRSEIRRAQRSEIPPGSKYFYISYLIYYPLVLLMFLLNCFADKPPRESKYPKSERPCPEENASFLSRLLFTWFDSLAWTGFRKPLEATDLWDMKPEDSAKEIVPLFEKHWQNTLDKSGSYSPTQNAQFKSDVDHVAFVNSKKKKEASVLPALVKSFGPTFAFGALLKLMQDILTFVSPQILGYIITYVRKGQYEWRGYFFTALLFITATIQTLLLAQYFNRMFIVGMRIRTALISTIYRKSLKISNSARKETTVGEIVNLMSVDAQKFIELTAFLNMIWSAPLQIILSLYFLWYELGPSVLAGLAVMIILIPVNGFIANKVKTLQIKQMKNKDERVKLMNEILSGIKVLKLYAWEPSFENQVLKIRNKEIKVLKSAAYLNAGTSFIWSCAPFLVSLVTFATFVLVDENNVLDANKAYVSISLFNILRFPMSMLPMMISNLVQTYVSVKRINRFMNSEELDPNNVTHDSFEADPLIIE--KGTFSW----GDDPILKNINIRLKKQTLTAVVGTVGSGKSSLISAFLGEMDKVSGRVNTVGRIAYVSQQAWIQNATLKDNILFGKKFDKVLYNKVIEMCALKADFEMLPGGDQTEIGEKGINLSGGQKQRVSLARAVYSDADIYFLDDPLSAVDSHVGKHIFDKVI-GPKGMLRYKTKVLVTHGITYLPQTDSIIVIKDGEVSESGTYQELLDKKGAFAEFLLQHITEDVDTDDGLGKQIKTDLDEIKDQLVGTALSEEVTRRLSRHRSRVSESHSECGSDRILNGSLQRQKSSDSTDKSLRRRAGSIEESKNDSPKGKLIEIEKAETGSVSWDVYKHYLKSIGLFLTFATILLNMVFQGFSIGSNVWLGVWANDSSLNVNGTVNTARRDLYLGVYGALGIGQVIVIFLATLALFIGSLNAARLLHNVILSNIMRVPSTTFYDVTPVGRILNRFSKDIDTLDTVLPMTLRGWITCFYAVIGTIAVISYTTPLFMLVIVPIGLLYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETVTGVQAIRAYGQQERFISESEYKVDLNQVCYYPSVISNRWLAVRLEMIGNLIILFASLFAVLGKEQ-DPSLVGLSITYALQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKNPSSAWPEHGSVEFNNYAVRYRPGLDLVLKGVDFHIKGGEKVGIVGRTGAGKSSLTLSLFRIIEAAQGQICIDGVNIAELGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWRALEHAHLKVFVSGLAAALNHEVSEGGENLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQTTIRTEFKTCTVLTIAHRLNTIMDSDRVIVLDKGQIVEFDTPANLLANPNTIFHGMCRDAGL 1531
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|749744033|ref|XP_011154502.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X7 [Harpegnathos saltator]) HSP 1 Score: 1232.62 bits (3188), Expect = 0.000e+0 Identity = 682/1543 (44.20%), Postives = 960/1543 (62.22%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAK--FTFTLVIL-VNLLGQFCYTSGH--VGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLE-----DKASCLSLLVFSWLDGLLWQGHKTPLKWKNL-PKSPRSMNVTDNVKAFTKQWRK--QAEDKL-------------VDFTSP-IRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVT---SEVETDELKVLATTT---KEPPKREVRVPSEEVESPEET-----------------------------DNLIEE--------TADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSD--RTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSR--ENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP--LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+D +L W T +P+VT C T+L+ VPCI I S + + Y ++ R + Y LF+ K T L+IL + LG Y S + V D P + ++ F+ ++L K+ G S LFLFW L +C + + I + + V + Y PI+L LF+ + VD +P+ +E ++E AS S L+F+W D L W+G + PL+ +L +P M + + V F K W K Q D++ VDF S + S+ P + K G L + L + ++ F+SPQ++++LI + + EP+W+G+FY ++L ++ L T+ Y + + +++R +L+ A+Y+K+LR+SN AR+ ++GE+ N MSVDAQR ++ Y+ + +PL I++A+YFL+ L A LAGL V I IP+N + VK LQ++Q+++KD R+KLMNE+L GIKVLKLYAWE F ++I +IR EI+++K L A +F + +P LV++ F YV +D +VL + FV+++LFN++R PL P + V+ +VS+KRIN+F+N ++D NV H ++ PHA+ + WD + PIL +N+ + G L A+VGTVG+GKSSLLS+ LGEM+KLSG+V +GSIAYV QQ WIQN TL+DN+LF + + + Y +VI C L PDL IL D+TEIGE GINLSGGQKQRV+LARAVY+D+D Y LDDPLSAVD+HVGK IF V+ G LK KTRVLVTH + +L ++DNIIVLK+G++ E G+Y++LL AF++FL+Q+ SE + E+K +T E ++ R S + ES E+ +N I+E T + LIE EK G V KVY Y+ SIG + + + +N WLS W+D N P D R YLGVYG +G+ Q + ++ C Q+SK++H +LL G++RSP+ FFD P+GRI+NRF D+D +D V+P + ++C ++ + V+ STPIF +VI+P+G +Y+F+QRF+V S+Q+KR ESV++S I++HFSE++TG + IRAY Q++F+HES++RV C + ++ ANRWL +R+E++GNL++FFAA+FAVL R +++S GI GLS++YAL I TLNW++RM ++ETN VA+ERI EY EA W PK WP+ G V F+++ RYR GLDLVL GI V +EKIGI GRTGAGKSSLTL+LFRIIEA G ILID DI++LGLH LRS++TIIPQDPVLF+G LR NLDP + H+D E+W AL+HAHLK + +L L HE+SEGGEN SVGQRQLICLARALLRKTK+L+LDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTILD D++ V G I E+ SP LL NPTS+ +M DAGL
Sbjct: 9 FCGTEFWDANLTWYTNNPDVTVCFEKTILIWVPCIFLWIFSSMEAYYILHSKRR----NVPYTWLFIIKQVLTIALIILSIVDLGMAIYESTYREVYSVDYCTP-----FIKIITFILASILMIYNRKY-GMRTSGLLFLFWFILALCGCVQFRTFINKLIDREKSTYPIVSYMIYYPIVLLLFVLNFLVDAEPKFSEYPTVESPCPEQSASYPSRLLFAWFDALAWKGFRKPLEASDLWSMNPEDMAM-EIVPKFDKYWDKNLQKTDEVESAKASFRKASGQVDFNSGRKKKIASILPPICKAFGATFLFGAFLKLVQDIMTFISPQLLRVLIAFVKEKEEPLWKGYFYAVLLFLTATLQTLVLSQYFHRMFLVGLRIRTALIAAIYRKALRMSNAARKESTLGEIVNLMSVDAQRFMDLTAYINMIWSAPLQIVLALYFLWEILGPAVLAGLAVMIILIPVNALIANKVKTLQIRQMKSKDERVKLMNEVLNGIKVLKLYAWEPSFEQQILKIRAKEIQVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLIDEKNVLNSSTAFVSLSLFNVLRFPLSMLPMMISNIVQAYVSVKRINKFMNMDDLDPNNVQHDPSE--PHALLIENGNFCWDMEHVDRPILQNINMHVEQGQLVAVVGTVGSGKSSLLSALLGEMDKLSGKVNTKGSIAYVSQQPWIQNATLQDNVLFGKALNKSVYNRVIEACALSPDLKILPAGDQTEIGEKGINLSGGQKQRVALARAVYNDSDNYFLDDPLSAVDSHVGKHIFENVI-GPGGLLKKKTRVLVTHGITYLPEVDNIIVLKDGEITECGTYKQLLEKRGAFADFLVQHLQEVHVDDGSEADLREIKQQLESTMGADELQQKLTRARSRKSESLSESGSITDRRSLNGSLKRQYSTESQQSANYIHNNSIKEKEATKTNNTGEKLIEVEKAETGSVKWKVYSHYLVSIGLFLSVATIVMNAIFQAFSIGSNVWLSVWSDDNMTTPNGTIDKGRQDMYLGVYGALGIGQATFVMLSQTALVVGCLQSSKLLHSELLFGILRSPLGFFDITPSGRILNRFGKDVDVIDNVLPPCIRAWLFCLTSVIATLFVISYSTPIFIAVILPIGALYYFIQRFYVASSRQLKRLESVSRSPIYSHFSESVTGASIIRAYGVQEQFIHESESRVDINQVCYYPSIIANRWLAVRLEMVGNLIIFFAALFAVLGRDSQDMSAGIVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGETTQEASWKNSEYTPPK---EWPSNGRVDFRNFKVRYREGLDLVLHGISFSVLGSEKIGIVGRTGAGKSSLTLALFRIIEAASGEILIDDIDISKLGLHDLRSKLTIIPQDPVLFSGTLRMNLDPFDNHTDDEVWRALEHAHLKSFVKNLPSSLLHEVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRHEFKDCTVLTIAHRLNTILDSDKVIVLDKGLIVEYDSPDTLLRNPTSSFYSMAKDAGL 1534 The following BLAST results are available for this feature:
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 19
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BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold1304_size49437:19244..23665- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>snap_masked-scaffold1304_size49437-processed-gene-0.4 ID=snap_masked-scaffold1304_size49437-processed-gene-0.4|Name=multidrug resistance-associated protein 1 isoform x3|organism=Tigriopus kingsejongensis|type=gene|length=4422bp|location=Sequence derived from alignment at scaffold1304_size49437:19244..23665- (Tigriopus kingsejongensis)back to top Synonyms
The feature 'multidrug resistance-associated protein 1 isoform x3' has the following synonyms
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