mitogen-activated protein kinase kinase kinase 15 isoform x4, snap_masked-scaffold866_size86999-processed-gene-0.5 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000000624 (supercontig:LSalAtl2s:LSalAtl2s109:73593:97815:1 gene:EMLSAG00000000624 transcript:EMLSAT00000000624 description:"maker-LSalAtl2s109-augustus-gene-1.21") HSP 1 Score: 1468.37 bits (3800), Expect = 0.000e+0 Identity = 751/1232 (60.96%), Postives = 910/1232 (73.86%), Query Frame = 0
Query: 21 EAEVMEAGGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGTPMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFR-KRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVHSDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQV--RTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLA--RRSSSGALLSPDVLEQIKSVDGMEGGNDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHL 1247
E E + QTDS+GS SGKT+ + + L KMEV CV+D + +L +RK AFE+ K +C + LH HIQFE+LDFGE NV+DSFYNADVA++DLSV+ QQ SLFYHLGVRESFGMKQNILL +DT+ E + ALK C+NY + YH+ VD G+ +VTD+ R L+ K+ +EMEIQSKVHMKEKFL+DLRKCRE+L+G L+ L MRRRLDDPN++S ++VHN+LISFREIQDYDAMVQLVQDL TLPNR YTQN AIIFL+AFALNRRHK+GDREKAY++ITKALE+KE EVPDIICLCGRICKDKFVESEYTD ML+ AIHWYRRGF+VQPNEYAGINLA LLVV+G DF TSPELQRIGM LNNLIGKKGSL +LEDYWDVATFFEISVLAEDY KA+ A+ECMF LKPP WYLKSTIGNI LISRFR K+ S E ++FDFW++ F A +++ + IRFPILIWEP+KVYMPS+VT+N++IEEKS+ I+N+C +C+ S S +KC ++H+WL TAPMIKTVT YKRDDRCLFLY+HSDDFQMYFPS WR+ FFDLVLK+TA+EEGMI DLD + + ++FEY+LD G + +LGRGTYGVVYAA DLNT +K+AVKEVPEKNLGDVQPLHEEIKLHSQLRH+NIVQY GS+SE+GYFKI MEQVPGGSLS+LLR KWGPLKGNE T+ +YSKQ+LEGLKYLHDQKIVHRDIKGDNVLVNTY+G+VKISDFGTSKRLAG+CP T TF GT+QYMAPE ID+G RG G PADIWSLGCTVVEMATG PPFIELGSPEAAMFKVG+YKMHPE+P ELS +AQQFI RCF P+ E R AS LL+D FI D KKK +H + L+ +S + + M+ P++ + + L ++ S +SS +K W + +R A + +++S V Q+ F R +S T+ SG ++ G++P ++P D + L R S++G L SP+VL+ + D FYLLKKDSQRR TLVKVLQ DR IC QW+ + L Q QI++DGIRG+IP+QN LE+A+SKLK+ELD+DGAKINQ+ +ALY+FQDA + R H+I+PHW+FALDNL+R+AVQ A+ IL+PELG HL
Sbjct: 32 ELENNSSSEGQTDSYGS----SGKTSNNNNQPIGTNSLKNVLKMEVCCVMDLYQPLHLNDRKAAFEDLKSSCSSSSANLH---HIQFERLDFGEVNVIDSFYNADVAVVDLSVLTQQRSLFYHLGVRESFGMKQNILLCMDTDRETSSALKSFCSNYVLLLYHL-VD-GSIVVTDSCTPSLSENVRIPLSAKMTYYLKEMEIQSKVHMKEKFLSDLRKCRETLSGNELRDSLQKMRRRLDDPNILSTDIVHNMLISFREIQDYDAMVQLVQDLGTLPNRSSYTQNSAIIFLFAFALNRRHKEGDREKAYKLITKALEKKEYEVPDIICLCGRICKDKFVESEYTDKAMLETAIHWYRRGFQVQPNEYAGINLAXLLVVSGQDFATSPELQRIGMVLNNLIGKKGSLQNLEDYWDVATFFEISVLAEDYNKAVSAAECMFGLKPPKWYLKSTIGNITLISRFRRKKCSSTDGGNENKLFDFWLEXFSFAIDEESTNSIRFPILIWEPTKVYMPSFVTINLEIEEKSVHITNICSKCIH--SGSLDSKCRQVHDWLLTAPMIKTVTNYKRDDRCLFLYIHSDDFQMYFPSGFWRECFFDLVLKLTADEEGMITDLDTELENVPISFEYELDSTGTRIILGRGTYGVVYAALDLNTXVKIAVKEVPEKNLGDVQPLHEEIKLHSQLRHRNIVQYLGSISEEGYFKIFMEQVPGGSLSSLLRDKWGPLKGNELTMVHYSKQILEGLKYLHDQKIVHRDIKGDNVLVNTYNGIVKISDFGTSKRLAGICPSTLTFTGTIQYMAPEXIDKGARGXGXPADIWSLGCTVVEMATGKPPFIELGSPEAAMFKVGFYKMHPEIPGELSTKAQQFISRCFVPEAENRPKASDLLEDSFIIDASKKK-----IHNNMSLKRRRLKSDGLKL---------MI--PDNHVSTRDWLLPYQRPSNSHSSNSSSMHHHPAPALTKTKRW-----KFXASRKMAXISNKSTSCVSSQNIFFSVYRPLS-----TAXSGLVQ----------GLTP--------ISPEDNISESFFELGSRRHSNTGILHSPEVLDTSTAPRDDCIQQDGFYLLKKDSQRRATLVKVLQADRMRICSQWH--------EALLKQSQLQIIVDGIRGYIPEQNISPLESALSKLKDELDYDGAKINQMQLALYIFQDAASPMFRLHNIQPHWVFALDNLIRNAVQXAILILSPELGQHL 1200
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000009799 (supercontig:LSalAtl2s:LSalAtl2s638:66051:147255:-1 gene:EMLSAG00000009799 transcript:EMLSAT00000009799 description:"maker-LSalAtl2s638-snap-gene-1.21") HSP 1 Score: 143.665 bits (361), Expect = 1.758e-34 Identity = 80/218 (36.70%), Postives = 125/218 (57.34%), Query Frame = 0
Query: 654 NVLGRGTYGVVYAARDLNTQIKVAVKEVP--EKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAG---LCPDTATFAGTLQYMAPEVIDRGQR-GYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVG 865
N G+G++G VY A + T +A+KE+P N + + +E+++ +RHK+I+ ++G G I ME P G+L L+ S L E+++ Y++Q+LE + LH+ +IVHRDIKG N+ + +K+ DFG + ++ + + F GT +MAPEV + G+G ADIWS+GC VVEMATG P+ EL S ++KVG
Sbjct: 1172 NDSGQGSFGKVYXAINNETGDIMAMKEIPLQPNNHKILMEIDDELRIFENIRHKHIINHYGVEIHRGEMLIFMEYCPEGTLEDLVTSTESGLV--ESSVRRYARQLLEAVTVLHENQIVHRDIKGANIFLTDEMQNIKLGDFGCAVKIKAQKTVVGELKEFVGTQAFMAPEVFTSNMKDGHGRAADIWSIGCVVVEMATGNIPWHELASDYQILYKVG 1387
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000004687 (supercontig:LSalAtl2s:LSalAtl2s245:332593:335632:-1 gene:EMLSAG00000004687 transcript:EMLSAT00000004687 description:"maker-LSalAtl2s245-augustus-gene-3.7") HSP 1 Score: 141.739 bits (356), Expect = 2.736e-34 Identity = 91/266 (34.21%), Postives = 152/266 (57.14%), Query Frame = 0
Query: 655 VLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLR-HKNIVQYHGSLSEDG-YFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRL-AGLCPDTA--TFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPF--IELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGK 913
+LG G Y + ARD+ T +AVK++P + L E++L S L + +I++ G++ E+ F + +E + GGS+S +L +G + E I Y +Q+L GL +LH ++HRDIKG N+L++T +KI DFG + L + L P + GT+ +MAPEVI RG+ YG +DIWS+GC ++EMA PP+ ++ + A ++K+ P++P LS F+L C + + ++R +A+ LL+ + + K
Sbjct: 575 LLGTGAYSACFQARDMRTGTLMAVKQIPLYSHTAEASL-SEVELLSNLGFNPHIIRLLGAIRENNSIFNVFIEWMSGGSISHIL-DIYGAFE--ERVIVGYVRQLLSGLDFLHSNTVLHRDIKGANLLLDTTGHHLKIGDFGAAVFLNSPLIPKGSDCELRGTIPFMAPEVI-RGE-SYGFKSDIWSVGCCIIEMAXQKPPWNTSDISNHLALIYKIAQSMDPPKIPNNLSVDCLDFLLSCLQINQDERPSAAQLLEHRVFNNYMK 834
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000008169 (supercontig:LSalAtl2s:LSalAtl2s490:223186:225761:-1 gene:EMLSAG00000008169 transcript:EMLSAT00000008169 description:"maker-LSalAtl2s490-snap-gene-2.28") HSP 1 Score: 137.887 bits (346), Expect = 1.843e-33 Identity = 93/273 (34.07%), Postives = 144/273 (52.75%), Query Frame = 0
Query: 642 AFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQE--LSERAQQFILRCFEPDPEKRATASLLLDDQFITDMG 912
AFEY + +G+G+ G+V A + NT+ +VA+K++ + + L E+ + H NIVQ H S + ++ME + GG+L+ ++ +E IA KQ L+ L YLH Q ++HRDIK D++L+ G VK+SDFG +++ P + GT +M+PE+I R YG DIWSLG V+EM G PPF P AM ++ + P++ + +S R F+ + DP +RATA+ LL F+ G
Sbjct: 341 AFEYVMK-------IGQGSTGIVCIAVEKNTKERVAIKKMDLRKQQRRELLFNEVVIMRDYHHPNIVQMHDSFLVNDELWVVMEFLEGGALTDIVTHA----SMDEDQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLGA-DGNVKLSDFGFCAQVSPELPKRKSLVGTPYWMSPEIISR--LPYGPEVDIWSLGIMVMEMVDGEPPFFN-EPPLQAMRRI-RDRPPPKLRNQSKVSPRLLGFLDKMLVRDPAQRATAAELLHHPFLRQAG 597
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000010271 (supercontig:LSalAtl2s:LSalAtl2s680:142787:148655:-1 gene:EMLSAG00000010271 transcript:EMLSAT00000010271 description:"maker-LSalAtl2s680-augustus-gene-1.23") HSP 1 Score: 134.42 bits (337), Expect = 1.024e-31 Identity = 86/251 (34.26%), Postives = 139/251 (55.38%), Query Frame = 0
Query: 671 NTQIKVAVKEVPEKNLGDVQPLH--EEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLST 919
N KVA+K++ N ++Q H E+++ +L H N+V + D ++M+ + GG L+ ++ NE ++ SK++L G+ YLH+ +++HRDIK DNVL++ G VKI+DFG + ++G TFAGT +MAPEV+ + + YG DIWSLG V+EM PP+++ +A + + LS+ +F+ RC + P KR+TAS LL+ +FI K +LS+
Sbjct: 1031 NLTEKVAIKQIDLDN-ENIQKFHLLMEVQVMRKLEHPNLVAFLDLFLTDKELWVVMDYMNGGPLTDVVLHTIL----NEPQMSAISKEVLSGINYLHNHELIHRDIKSDNVLLSV-KGDVKITDFGFTANVSG-DRMRKTFAGTPYWMAPEVVKK--QTYGKSVDIWSLGILVIEMVDRHPPYMDETPLQAMYYISKKKSPPIKSKGILSKEMSKFLERCLQFQPNKRSTASELLEHEFI---AKATRLSS 1269 HSP 2 Score: 80.8777 bits (198), Expect = 2.382e-15 Identity = 65/219 (29.68%), Postives = 107/219 (48.86%), Query Frame = 0
Query: 654 NVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLH---EEIKLHSQLRHKNIVQYHGSLSE-DGYFKII-MEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLV---NTYSGVVKISDFGTSKRLAGLCPDTATFA---GTLQYMAPEVIDRG------QRGYGAPADIWSLGCTVVEMATGLPPFIELG 855
+VLG+G G V+ + + VAVK + L ++P E ++ +++H+NIV+ E +G K+I ME GGSL LL +E + G+ +L D +VHRD+K N++ + + V K++DFG ++ L D F GT +Y+ P++ +R + +GA D+WS+G T+ +ATG PF G
Sbjct: 16 SVLGKGATGAVFQGVNKHNGETVAVKTFNQ--LSHMRPQEVQMREFEVLQKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNLLDDPENSYGLHEDEWLXVLSHLSAGMNHLRDNNLVHRDLKPGNIMKFIKDDGNIVYKLTDFGAARELE----DDQQFVSLYGTEEYLHPDMYERAVLRKTVGKTFGATVDLWSIGVTLYHVATGNLPFRPFG 228
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000011184 (supercontig:LSalAtl2s:LSalAtl2s760:424402:425388:1 gene:EMLSAG00000011184 transcript:EMLSAT00000011184 description:"augustus_masked-LSalAtl2s760-processed-gene-3.6") HSP 1 Score: 123.25 bits (308), Expect = 1.296e-30 Identity = 93/285 (32.63%), Postives = 147/285 (51.58%), Query Frame = 0
Query: 616 DLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHE---EIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIA-YYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKR 896
D+ +M NE G NS +E + + GR LG+G +G VY AR+ ++ VA+K + + L H+ EI++ LRH +I++ +G ++ +I+E G L LL+++ PLK E T+A Y QM L YLH +K++HRDIK +N+L+++ G +KI+DFG S + T GTL Y++PE+I+ R + D+WSLG E G PPF E + + K+ + E P +S A+ I + + PE+R
Sbjct: 29 DVSSEMPNNENGK--------NSSDKRWELNDFDIGRP--LGKGKFGNVYLAREKKSKFIVALKVMFKNQLKKANVEHQLRREIEIQXHLRHPHILRLYGYFYDETRVYLILEFASKGELYKLLKNE--PLKRFEETLAARYIYQMSGALDYLHSKKVIHRDIKPENLLLDS-KGNLKIADFGWS--VHAPSSRRGTMCGTLDYLSPEMIE--GRSHDEKVDLWSLGILCFEFLVGKPPF-ETDNQQETYKKITNVDI--EWPSFISPEARDLISKLLQKIPERR 293
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000002821 (supercontig:LSalAtl2s:LSalAtl2s1625:7590:11121:1 gene:EMLSAG00000002821 transcript:EMLSAT00000002821 description:"maker-LSalAtl2s1625-augustus-gene-0.21") HSP 1 Score: 128.642 bits (322), Expect = 3.696e-30 Identity = 93/296 (31.42%), Postives = 142/296 (47.97%), Query Frame = 0
Query: 609 SWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVA-VKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLL 903
+W FF LK + G +D++ + + FE+ + + LG G G V+ + + + V VKEV E N+ ++ L H NIVQ+ G ++ + I+ME P G L LR G K + ++KQ+ G+KYLHD KI+HRD+K NVL+ ++KISDFGTS+ +FAGT+ +MAPEVI DIWS G + E+ T P+ + S A ++ VG + +P E + I +C+ P P R + +L
Sbjct: 132 TWYDGFFG-CLKPVLSMMGKQKPVDKSEDDWEIPFEHISNLEW----LGSGAQGAVFVGKLHSEYLAVKKVKEVAETNIYHLR----------HLNHPNIVQFLGVCTQSPVYAILMEYCPYGPLFYFLRD--GKDKVPPKRLVAWTKQIASGMKYLHDNKIIHRDLKSPNVLIGR-KEIIKISDFGTSRTWTEQS-TYMSFAGTVAWMAPEVI--RNEPCSEKVDIWSFGVCLWELLTCEVPYKNVDS-SAVIWGVGSNSLQLPIPSTCPEGFKLLIKQCWSPKPRNRPSFKHIL 405
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000002450 (supercontig:LSalAtl2s:LSalAtl2s146:313700:318004:-1 gene:EMLSAG00000002450 transcript:EMLSAT00000002450 description:"maker-LSalAtl2s146-snap-gene-3.9") HSP 1 Score: 126.331 bits (316), Expect = 1.848e-29 Identity = 93/270 (34.44%), Postives = 137/270 (50.74%), Query Frame = 0
Query: 647 LDEQGRKNVLGRGTYGVVYAA-RDLNTQIK--VAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEV--IDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMF---KVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFI 908
LD+ + +G GTYG VY + R + I AVK + + D + +EI + RH NIV Y+GS I ME G SL + GPL E IA+ ++ L+GL YL +HRDIKG N+L++ G VK++DFG S ++ +F GT +MAPEV ++R + GY DIW++G T +E+A PP +L P A+F K GY + + S+ F+ +P+KR A LL ++F+
Sbjct: 28 LDDYELLHRIGSGTYGDVYKSKRRSPSSIGEFAAVKVIKLEQGDDFSVIQQEILMMKDCRHPNIVAYYGSYLRRDKLWIAMEYCGGSSLQDIYHIT-GPL--TEKQIAFMCRETLKGLAYLXSMGKMHRDIKGANILLSD-KGDVKLADFGVSAQITATLSKRKSFIGTPYWMAPEVAAVER-KGGYNHLCDIWAVGITAIELAELXPPMFDL-HPMRALFLMSKSGYTPPTLKDKSKWSKDFHLFLKESLTKNPKKRPGAEKLLFNRFV 291
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000008315 (supercontig:LSalAtl2s:LSalAtl2s503:403257:406200:1 gene:EMLSAG00000008315 transcript:EMLSAT00000008315 description:"maker-LSalAtl2s503-augustus-gene-4.13") HSP 1 Score: 122.479 bits (306), Expect = 9.611e-29 Identity = 80/267 (29.96%), Postives = 128/267 (47.94%), Query Frame = 0
Query: 649 EQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDV---QPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHP---EVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFIT 909
++GR LG+G + Y D+ + VA K VP+ L + + +EI+L H IV+ + + + II+E SL L + + E Y+ Q+L+G YLH+ K++HRD+K N+ +N VKI DFG + ++ T GT Y+APEV+ ++G+ D+WSLGC + + G PPF E K Y ++ VP + A+ I + + DP KR + +L D+F+T
Sbjct: 32 QKGR--FLGKGGFAKCYELTDMASGEVVAGKIVPKSLLTKQHQREKMSQEIRLQKTFNHTYIVKLYSYFEDSNFVYIILELCRRRSLMELHKRRKAI---TEPETRYFMNQILQGCLYLHENKVIHRDLKLGNIFLND-DMEVKIGDFGLATKVDYFGERKRTLCGTPNYIAPEVL--AKKGHSYEVDVWSLGCIMYTLLVGKPPF------ETQTLKDTYARIKKNEYHVPSRVGPLAKNLITKLLQSDPSKRPAVAEILKDEFMT 284
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000007549 (supercontig:LSalAtl2s:LSalAtl2s436:235719:254938:-1 gene:EMLSAG00000007549 transcript:EMLSAT00000007549 description:"maker-LSalAtl2s436-augustus-gene-2.9") HSP 1 Score: 122.479 bits (306), Expect = 4.133e-28 Identity = 103/316 (32.59%), Postives = 155/316 (49.05%), Query Frame = 0
Query: 623 ANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIK-LHSQLRHKNIVQYHGSL------SEDGYFKIIMEQVPGGSLSALLRSKWG-PLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVI---DRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQL 927
AN G+ D+D A + +DL E ++G GTYG VY R T A+K V + + + + EI L H+NI Y+G+ +D ++ME GS++ L++S G LK E IAY S+++L GL +LH K++HRDIKG NVL+ T + VK+ DFG S +L TF GT +MAPEVI + + Y +D+WSLG T +E A PP ++ P A+F + + S + + FI D +R LL F+ D ++++ R+H+ L
Sbjct: 2 ANNSGL-DDIDLASLKDPAGI-FDLME-----IVGNGTYGQVYKGRHTMTGQLAAIK-VMDVTEDEEEEIKLEINVLKKYSHHRNIATYYGAFIKKCPAGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLK--EDWIAYISREVLRGLTHLHACKVIHRDIKGQNVLL-TDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPEATYDNRSDLWSLGITALEXAEAQPPLCDM-HPMRALFLIPRNPPPRLKSKRWSSKFKNFIETVLVKDYHQRPYTDQLLKHPFVRDQPTERQV--RIHIKDML 303
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|928589314|sp|Q21029.4|NSY1_CAEEL (RecName: Full=Mitogen-activated protein kinase kinase kinase nsy-1; AltName: Full=Apoptosis signal-regulating kinase 1; Short=ASK-1; AltName: Full=Neuronal symmetry kinase 1) HSP 1 Score: 891.723 bits (2303), Expect = 0.000e+0 Identity = 566/1481 (38.22%), Postives = 821/1481 (55.44%), Query Frame = 0
Query: 63 KMEVVCVIDTHAHANLPERKLAFEEA-KFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFL---DTNGEDTLALKHSCANYSFVSYHIPVDHGTPMVTDATGVYEGSG---QRTSLATK-------LKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALE-RKENE------VPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPG-DLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNL---CQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMT----ANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGS--LSEDG---YFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFIT----DMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIA-----ESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSH---VLTPTD-QLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGGNDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWN-LLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTP---NSPLEEALLASSGLSSHNPEP----TNRPPD---------------------------EELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQRSREIR 1459
K+ VV VID NL R++A ++ K A L ++ + I F+KLDFGE LD FYNADVA++D++V QQ SL YH+GVRES G N++L D ALK + A+ + Y D D + S RT++ K +KQ+ + +++++ H +EKF++DLRK RE G+ L MR RLD+P+V+ + V +++S+R+ Q+Y M++LV DLK +P+ P I + YAFALNRR+KDGDR+ A + +E ENE PD++CL GRI KDKF+ S Y D L AI WYRR FE+ P EY+GINL TLL +G F + E+Q+I + LN+L+G+KG+L +L +YWDVAT+FE+SVLAE+Y KA +A+ M KLKPP WYLKST+ NIKLI+R + E+Q F FW ++F++A E D R+P+LI E +K + PSY+T+N EE ++ +S++ QQ H S + IH W F IK VT KRDDR LFLYVH SDDF + FP+++ +K +D + M N +G + ++E + FEY+L + VLG+GTYG VYAARD++TQ ++ VKE+ K +VQPL EEI LHS L H NIVQY G + +DG +F I ME VPGGSLS+LLRSKWGP+ NE + YY KQ+LEGLKYLH+ KIVHRDIKGDNVLVNTYSGV KISDFGT KRLAGL P T TF GTLQYMAPEVID GQRGYGAPADIWS GCT+VEMATG PPF+E+ +P+AAMF+VG +K HP +P E++E+ + FI CF P+ R +A LL D FI + + + S +T+++ + ++ S+ +M+ S I E + +L +G+ V S + S+ R ++ L+ +++ H ++ + S + SS+G SH + SP +D +H +++P G PL SS ALL+ + ++ + + F++L+KDS+RR +L + +Q + I W+ LL+ + + + ++ ++L+DG+R F+ ++ ++ I ++ LD+D AKI QI++ALY F D++ LR IKPHWMFAL NL+ SAVQ A++IL+P+L L D+L + + R + + + G + + S P + +EL ++EEN L+ +LL+++ + L+ + + D + P P+ A +S +P TN+PP EELV WLR L++++ S+ +E T SD+M ++RD+L +G+ G RI +AI R R+ R
Sbjct: 62 KLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVN----LTRIDFDKLDFGETETLDLFYNADVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIVYIHHQDSNQLQSYDKNNNDDDSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREKFMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPPVWYLKSTMENIKLINRCAATISP--IEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILELNKEFTPSYLTLNN--EEGTVILSHVLENSQQKKIHQS-----ELRGIHRWHFARNNIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVL---SNPDNEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPM--NENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEK----KEKSKNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSH-------VHSQTVSNALSTAREEKKLH-----------LKIDHARNRTFSSSSPVPDGQSSAG-TNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNTMGSPL------SSAALLNRTISDESSNS------SSRFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNLITSAVQCAISILSPDLSLLLH----AQDNLPSTSSIVAIR-----------------NSSLSEGEALIESRPPSREERVREDR--------KELRTLQEENEILIERLLQVERELNAQLKSGITRANRFRDFAMYRNTYPPFRTPPVAHAPPTPPFSASCGAQPSGTFTNQPPSFASIKPIAQKIIMPPGTENNYQVTRVQEELVSWLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGEVRERQRR 1460
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|116248533|sp|Q6ZN16.2|M3K15_HUMAN (RecName: Full=Mitogen-activated protein kinase kinase kinase 15; AltName: Full=Apoptosis signal-regulating kinase 3; AltName: Full=MAPK/ERK kinase kinase 15; Short=MEK kinase 15; Short=MEKK 15) HSP 1 Score: 874.389 bits (2258), Expect = 0.000e+0 Identity = 437/842 (51.90%), Postives = 584/842 (69.36%), Query Frame = 0
Query: 105 IQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKH--------SCANYSFVSYHIPVDHGTPMVTDATGVY--EGSGQRTS------------------LATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKK 916
+ F +LDFGE VLD+FY+ADVA++D+S V +Q SLFYHLGVRESF M N++L+ DT+ + L+LK S NY F+ Y +VT + E QR + L + L +++ + S V+ KE L D+RK RE GE L K L ++ R+D+ V++ +++ N+L+S+R+IQDYDAMV+LV+ L+ LP + Q+ I F YAFALNRR+ GDREKA Q++ + L+ ++ PD+ CLCGRI KD F++S+ D AI WYR+GFE+Q + Y+GINLA LL+VAG F TS EL++IG++LN+L+G+KGSL + +YWDV FF +S+LA D GKA+QA+E +FKLKPP WYL+S + N+ LI RF+K T +H P ++ +FW+D +A + L RFP+L+ EP+KVY PSYV++N + EE+++ + H+S + ++HEW FTA IK +++ K D+RC FLYVH SDDFQ+YF +E +FF LV +M N G +L+ + +TL +EYD D G + VLG+GTYG+VYA RDL+ Q+++A+KE+PE++ QPLHEEI LH L+H+NIVQY GS+SE+GY KI MEQVPGGSLSALLRSKWGP+K E TI +Y+KQ+LEGLKYLH+ +IVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAG+ P T TF GTLQYMAPE+ID+G RGYGAPADIWSLGCT++EMAT PPF ELG P+AAMFKVG +K+HPE+P+ LS A+ FIL CFEPDP KRAT + LL + F+ + K KK
Sbjct: 101 VPFGELDFGETAVLDAFYDADVAVVDMSDVSRQPSLFYHLGVRESFDMANNVILYHDTDADTALSLKDMVTQKNTASSGNYYFIPY---------IVTPCADYFCCESDAQRRASEYMQPNWDNILGPLCMPLVDRFISLLKDIHVTSCVYYKETLLNDIRKAREKYQGEELAKELARIKLRMDNTEVLTSDIIINLLLSYRDIQDYDAMVKLVETLEMLPTCDLADQH-NIKFHYAFALNRRNSTGDREKALQIMLQVLQSCDHPGPDMFCLCGRIYKDIFLDSDCKDDTSRDSAIEWYRKGFELQSSLYSGINLAVLLIVAGQQFETSLELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFSVSMLAHDVGKAVQAAERLFKLKPPVWYLRSLVQNLLLIRRFKK-TIIEH-SPRQERLNFWLDIIFEATNEVTNGL-RFPVLVIEPTKVYQPSYVSINNEAEERTVSL--------WHVS---PTEMKQMHEWNFTASSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEEQCSRFFSLVKEMITNTAGSTVELEGETDGDTLEYEYDHDANGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFLRQVNKGKK 916 HSP 2 Score: 186.037 bits (471), Expect = 4.347e-46 Identity = 137/415 (33.01%), Postives = 209/415 (50.36%), Query Frame = 0
Query: 1049 SGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLS-PD---VLEQIKSVDGMEGGNDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHP-QIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTPNSPLEEALLASSGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAI-QTQRSRE 1457
S + VSP D Q L + A R G LLS PD LE E + +LL+KDS+RR L K+L +++ + +++ + + LS H + ++ +R FI + ISKLK +LDFD + I+QI + L+ FQDAVN LR+H I+PHWMFA+DN++R AVQ+AVTIL PEL AH +PT + GV D E +G PG A P Q H +L ++R+E +RLL L+E + +YQ+LLR L ++ Q+L L + L S+ ++ + P + D+EL+DWLR + ++++ V E T SD+++ ++++DLR L LR G R+W A+ Q +R++E
Sbjct: 945 SSEHGSVSPDSDAQPDALFERTR--------APRHHLGHLLSVPDESSALEDRGLASSPEDRDQGLFLLRKDSERRAILYKILWEEQNQVASNLQECVAQSSEELHLSVGHIKQIIGILRDFIRSPEHRVMATTISKLKVDLDFDSSSISQIHLVLFGFQDAVNKILRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELRAHF----------------EPTCETEGVDK---DMDEAEEGYPPATG-------PG--------QEAQPHQQHLSLQLGELRQETNRLLEHLVEKEREYQNLLRQTLEQKTQELYHL------------QLKLKSNCITENPAGPYGQRTDKELIDWLRLQGADAKTIEKIVEEGYTLSDILNEITKEDLRYLRLRGGLLCRLWSAVSQYRRAQE 1305
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|160012147|sp|A2AQW0.1|M3K15_MOUSE (RecName: Full=Mitogen-activated protein kinase kinase kinase 15; AltName: Full=MAPK/ERK kinase kinase 15; Short=MEK kinase 15; Short=MEKK 15) HSP 1 Score: 866.685 bits (2238), Expect = 0.000e+0 Identity = 433/839 (51.61%), Postives = 583/839 (69.49%), Query Frame = 0
Query: 105 IQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKH--------SCANYSFVSYHIPVDHGTPMVTDATGVYEGSGQRTS-----------------LATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKK 916
+ F +LDFGE VLD+FY+ADVAI+D+S + +Q SLFYHLGVRESF M N++L+ DT+ + L+LK S NY F+ Y + TP D + +R S L + L +++ + S + KE L D+RK RE G+ L K L ++ R+D+ V++ +++ N+L+S+R+IQDYDAMV+LV+ LK LP + Q+ I F YAFALNRR+ GDREKA QV+ + L+ ++ PD+ CLCGRI KD F++S + AI WYR+GFE+Q + Y+GINLA LL+V+G F TS EL++IG++LN+L+G+KGSL + +YWDV FF +S+LA D GKA+QA+E +FKLKPP WYL+S + N+ LI RF+K ++H P ++ +FW+D +A + L RFP+L+ EP+KVY PSYV++N + EE+++ + H+S + +IHEW FTA IK +++ K D+RC FLYVH SDDFQ+YF +E +F LV +M N G +L+ + +TL +EYD D G + VLG+G+YG+VYA RDL+ Q+++A+KE+PE+++ QPLHEEI LH L+H+NIVQY GS+SE+GY KI MEQVPGGSLSALLRSKWGP+K E TI +Y+KQ+LEGLKYLH+ +IVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAG+ P T TF GTLQYMAPE+ID+G RGYGAPADIWSLGCT++EMAT PPF ELG P+AAMFKVG +K+HPE+P+ LS A+ FIL CFEPDP+KR TA+ LL + F+ + K KK
Sbjct: 105 VPFGELDFGETAVLDAFYDADVAIVDMSDISRQPSLFYHLGVRESFDMANNVILYYDTDADTALSLKDMVTQKNTASSGNYYFIPYTV-----TP-CADYFCCESDAQRRASEYMQPNWDTILGPLCMPLVDRFTSLLKDIRVTSCAYYKETLLNDIRKAREKYQGDELAKELTRIKFRMDNIEVLTSDIIINLLLSYRDIQDYDAMVKLVETLKMLPTCDLADQH-NIKFHYAFALNRRNSTGDREKALQVMLQVLQSCDHPAPDMFCLCGRIYKDIFLDSGCEEDASRDSAIEWYRKGFELQSSLYSGINLAVLLIVSGQQFETSMELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFTVSMLASDIGKAVQAAERLFKLKPPVWYLRSLVQNLLLIQRFKKPI-TEH-SPRQERLNFWLDIIFEATNEVTNGL-RFPVLVIEPTKVYQPSYVSINNEAEERTVSL--------WHVS---PTEMKQIHEWNFTASSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEDQCNRFCSLVKEMLNNGVGSTVELEGEADGDTLEYEYDHDANGERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFLRQVNKGKK 920 HSP 2 Score: 186.037 bits (471), Expect = 5.236e-46 Identity = 122/355 (34.37%), Postives = 189/355 (53.24%), Query Frame = 0
Query: 1104 EGGNDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPL-DPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQ---ELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTPNSPLEEALLASSGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
E + +LL+KDS+RR L ++L +++ + + + + + LS H + ++ +R FI + A ISKLK +LDFD + INQI + L+ FQDAVN LR+H I+PHWMFA+DN++R AVQ+AVTIL PEL AH +P A +D G PL D ++ E V+ P G P V Q HQ +LS++R+E +RL L++ + +YQ+LLR L ++ Q+L L S+G + + P P D EL+DWL+ ++ ++++ V ED T SD+++ ++++DLR L LR G R+W A+ R
Sbjct: 1002 EERDPGLFLLRKDSERRAILYRILWEEQNQVASNLQECVVQSSEELLLSVSHIKQIIGILRDFIRSPEHRVMAATISKLKVDLDFDSSSINQIHLILFGFQDAVNRILRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELQAHF-EP--------ASETEGVDKDTEVEGDYPLVDLLSQE-----------VHVTPRGTRP-GSVAIQEGQPHQQDPSLQLSKLRQETNRLWEHLVQKEREYQNLLRLILDQKTQELYHLQLQ------------YKSNGGTENPPPPDGLGTDRELIDWLQLQGVDANTIEKIVEEDYTLSDILNDITKEDLRCLRLRGGVLCRLWHAVSQHR 1323
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|341941007|sp|O35099.3|M3K5_MOUSE (RecName: Full=Mitogen-activated protein kinase kinase kinase 5; AltName: Full=Apoptosis signal-regulating kinase 1; Short=ASK-1; AltName: Full=MAPK/ERK kinase kinase 5; Short=MEK kinase 5; Short=MEKK 5) HSP 1 Score: 833.173 bits (2151), Expect = 0.000e+0 Identity = 422/878 (48.06%), Postives = 589/878 (67.08%), Query Frame = 0
Query: 84 AFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKH--------SCANYSFVSYHIPVDHGTPMVTDAT---GVYEGSGQR---------TSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYV--HSDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPV 939
+ EA A G + LH F KLDFGE VLD FYNAD+A++++S +Q SLFYHLGVRESF M NI+L+ DTN + +LK NY+F+ Y + H D++ G+ E L + QL + + S + +E L+D+RK R TG+ L L +R+R+D+ V++ ++V N+L+S+R+IQDYD++V+LV+ L+ LP + + + + F YAFALNRR+ GDR KA ++ ++ +E D+ CL GRI KD F++S +TDT W+++ FE +P +GIN A LL+ AG+ F +S EL+++G+KL++L+GKKG+L L+ YW+V F SVLA D+ + IQASE +F+LK P WYLKS + I + F K T ++ ++++ DFW+D+ V+A + D ++RFP+LI EP+K+Y PSY+++N ++EEK++ I ++ + IHEW F A ++ V+I K ++RC FLYV +SDDFQ+YF +E ++FF++V +T E+G A+ D ++L ++Y+ DE G + VLG+GTYG+VYA RDL+ Q+++A+KE+PE++ QPLHEEI LH L+HKNIVQY GS SE+G+ KI MEQVPGGSLSALLRSKWGPLK NE TI +Y+KQ+LEGLKYLHD +IVHRDIKGDNVL+NTYSGV+KISDFGTSKRLAG+ P T TF GTLQYMAPE+ID+G RGYG ADIWSLGCT++EMATG PPF ELG P+AAMFKVG +K+HPE+P+ +S A+ FIL+CFEPDP+KRA A+ LL D+F+ KKKK +L + E+ RS S+PV
Sbjct: 122 SLREACEAVGATLETLH------FGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTVCTGNYTFIPYMV-TPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFVQLLKVAQASSSQYFRESILSDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHH-HVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEEQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHLRVIQASEKLFRLKTPAWYLKSIVETILIYKHFVKLT-TEQPSAKQELVDFWMDFLVEATKTDV-TVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVL-----------PDDKKGIHEWNFGASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKRFFEMVNTIT-EEKGRGAE-DGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFLKVSSKKKKTQPKLSALSTGSNEYLRSISLPV 976 HSP 2 Score: 191.815 bits (486), Expect = 7.536e-48 Identity = 127/364 (34.89%), Postives = 195/364 (53.57%), Query Frame = 0
Query: 1104 EGGNDNFYLLKKDSQRRLTLVKVLQQDRAAICRQW--NLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHL--------ADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAH-VNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTPNSPLEEALLASSGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQRSR 1456
E + F++L+KDS+RR TL ++L +D+ + R +L E P L H L+ +R F+ +R + +SKLK ELDFD I+Q+ + L+ FQDAVN LR+H+IKPHWMFALD+++R AVQ+A+TIL PEL H ADPE DL + ++L P A D +TSGVST++S ++H +AH ++ +L +++ E +RLL +L+ + + Q LL + E+ Q++ H + P++ L+S P D EL WLR ++ ++ RF+ ED T DV+ ++RDDL+ L LR G +WKAI R++
Sbjct: 1042 EEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPK--LKWEHITTLISSLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADPE----DLDV----EDEHEELSSNQTVRRPQAITEDAVATSGVSTLSST------VSHDSQNAHRSLN--VQLGRMKIETNRLLEELVRKERELQALLHQAIEEKDQEI----RHLKLKSQPIDIPGFPVCHLNS----PGTTTEDSELPGWLRENGADEDTISRFLAEDYTLVDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNK 1379
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|6685617|sp|Q99683.1|M3K5_HUMAN (RecName: Full=Mitogen-activated protein kinase kinase kinase 5; AltName: Full=Apoptosis signal-regulating kinase 1; Short=ASK-1; AltName: Full=MAPK/ERK kinase kinase 5; Short=MEK kinase 5; Short=MEKK 5) HSP 1 Score: 831.247 bits (2146), Expect = 0.000e+0 Identity = 425/878 (48.41%), Postives = 587/878 (66.86%), Query Frame = 0
Query: 84 AFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKH--------SCANYSFVSYHIPVDHGTPMVTDAT---GVYEGSGQR---------TSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYV--HSDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPV 939
A + + AC + + L E +H F KLDFGE VLD FYNAD+A++++S +Q SLFYHLGVRESF M NI+L+ DTN + +LK NY+FV Y I H D++ G+ E L + QL + + S + +E L D+RK R TG+ L L +R+R+D+ V++ ++V N+L+S+R+IQDYD++V+LV+ L+ LP + + + + F YAFALNRR+ GDR KA ++ ++ + D+ CL GRI KD F++S +TDT W+++ FE +P +GIN A LL+ AG+ F +S EL+++G+KL++L+GKKG+L L+ YW+V F SVLA D+ + IQASE +FKLK P WYLKS + I + F K T + +E + DFW+D+ V+A + D ++RFP+LI EP+K+Y PSY+++N ++EEK++ I ++ + IHEW F+A ++ V+I K ++RC FLYV +SDDFQ+YF +E +KFF++V +T EE + + S+ L ++Y+ DE G + VLG+GTYG+VYA RDL+ Q+++A+KE+PE++ QPLHEEI LH L+HKNIVQY GS SE+G+ KI MEQVPGGSLSALLRSKWGPLK NE TI +Y+KQ+LEGLKYLHD +IVHRDIKGDNVL+NTYSGV+KISDFGTSKRLAG+ P T TF GTLQYMAPE+ID+G RGYG ADIWSLGCT++EMATG PPF ELG P+AAMFKVG +K+HPE+P+ +S A+ FIL+CFEPDP+KRA A+ LL D+F+ KKKK +L + E+ RS S+PV
Sbjct: 112 ALQSLREACETVGATL-ETLH--FGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMI-TPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHH-HVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQE-LVDFWMDFLVEATKTDV-TVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVL-----------PDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTIT--EEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPV 969 HSP 2 Score: 189.119 bits (479), Expect = 5.704e-47 Identity = 130/366 (35.52%), Postives = 197/366 (53.83%), Query Frame = 0
Query: 1104 EGGNDNFYLLKKDSQRRLTLVKVLQQDRAAICRQW--NLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGV----GHIPLDPVAHEP-----DGASTSGVSTVNSIPGGLNPMAH-VNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTPNSPLEEALLASSGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQRSRE 1457
E + F++L+KDS+RR TL ++L +D+ I R +L E P L H L+ +R F+ +R + +SKLK ELDFD I+Q+ + L+ FQDAVN LR+H+IKPHWMFALD+++R AVQ+A+TIL PEL H + A ++DL V P + P D +TSGVST++S ++H SAH ++ +L +++ E +RLL +L+ + + Q LL + E+ Q++ H + P+E L L+S TN D EL DWLR ++ ++ RF+ ED T DV+ ++RDDL+ L LR G +WKAI R+++
Sbjct: 1035 EEKDSGFFMLRKDSERRATLHRILTEDQDKIVRNLMESLAQGAEEPK--LKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFS---------LASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSST------VSHDSQSAHRSLN--VQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEI----KHLKLKSQPIEIPELPVFHLNSSG---TNT-EDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQ 1373
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|150384404|sp|Q9WTR2.4|M3K6_MOUSE (RecName: Full=Mitogen-activated protein kinase kinase kinase 6; AltName: Full=Apoptosis signal-regulating kinase 2) HSP 1 Score: 704.516 bits (1817), Expect = 0.000e+0 Identity = 368/843 (43.65%), Postives = 512/843 (60.74%), Query Frame = 0
Query: 98 PLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKH--------SCANYSFVSYHIPVDHGTPMVTDA---TGVYEGSGQR--------TSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACED---DPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYV--HSDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKK 916
P ++ + F L G+ LDSFYNADV ++++S + Q SLFYHLGVRESF M N+LL D AL+ +Y+ + Y + G + DA G+ +G Q T L +L +L + S + +E D+R+ RE +G+ L++ L ++RRLD ++S ++V N+L+S+R++QDY A+++LV+ L+ LP V Q+ + F Y FALNRR++ GDREKA V+ ++ + PD+ C+CGRI KD F S + + L+QA HWYR+ F+V+P+ ++GIN A LL+ AG F S EL+ IGMKL L+ +KG + ++ YWDV + +LA D + + A+E ++KL P WYL S + L FR P FW+ + + +C+ P + +L+ E +KV +P+ L+I +S+ W F I ++ K D RC FLY + D Q+ FPS Q+F L+ + N + + E L F+Y+ E G + VLGRGTYGVVYA RD +T++++A+KE+PE++ QPLHEEI LH +LRHKNIV+Y GS S+ GY KI ME+VPGGSLS+LLRS WGPLK NE+TI++Y++Q+L+GL YLH+ +IVHRDIKGDNVL+NT+SG++KISDFGTSKRLAG+ P T TF GTLQYMAPE+ID+G RGYG ADIWSLGCTV+EMATG PPF ELGSP+AAMF+VG YK+HP VP LS AQ F+LR FEPDP RA+A LL D F+ GK+ +
Sbjct: 88 PPPQLRSLPFATLALGDTAALDSFYNADVVVLEVSSSLAQPSLFYHLGVRESFSMTNNVLLCSQAELPDLQALREDVFQKNSDCVGSYTLIPYVV-TATGRVLCGDAGLLRGIADGLVQAGAGTEALLTPLVGRLVRLLEATPTDSCGYFRETIRQDIRQARERFSGQQLRQELARLQRRLDSVELLSPDIVMNLLLSYRDVQDYSAIIELVETLQALPTCDVAEQH-NVCFHYTFALNRRNRPGDREKALAVLLPLVKYEGPVAPDLYCMCGRIYKDMFFTSGFQNAGHLEQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSEELRLIGMKLACLLARKGCVEKMQYYWDVGFYLGAQILANDPIQVVLAAEQLYKLNAPIWYLVSVMETFLLYQHFRPTPEPSGGPPLRA--HFWLHFLLQSCQPFKMAPPQEDQCLVLVLEINKVLLPA-----------RLEIQGTDPMSAVTLSLLEPETQEDPSSWTFPVTSICGISTSKLDQRCCFLYALPPAQDVQLCFPSVERCQRFCGLIQVLVMNPDSSAPTEEAEGAREVLEFDYEYSETGERLVLGRGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHKRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLSYLHENRIVHRDIKGDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPVPGSLSAEAQAFLLRTFEPDPRLRASAQELLGDPFLQP-GKRSR 914 HSP 2 Score: 67.781 bits (164), Expect = 7.083e-10 Identity = 44/131 (33.59%), Postives = 69/131 (52.67%), Query Frame = 0
Query: 1112 LLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPE 1242
LL ++S+RR L VL+Q+ + NLL ++ D LS+ H ++L+ + I NR L + L+ +L + L+ F DAV LR I+PHWMF LD+L+ AV++A+ +L E
Sbjct: 994 LLHQESKRRAMLAAVLEQEVPTLAE--NLLEQEQ--DSRLSKIHVELLLRCLGAQIHTPNRRQLAQELRTLQAQLRAQSLGPALLKGPLFAFPDAVKQILRRRQIRPHWMFVLDSLLSRAVRAALAVLDAE 1120
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|262527573|sp|O95382.3|M3K6_HUMAN (RecName: Full=Mitogen-activated protein kinase kinase kinase 6; AltName: Full=Apoptosis signal-regulating kinase 2) HSP 1 Score: 697.197 bits (1798), Expect = 0.000e+0 Identity = 373/876 (42.58%), Postives = 524/876 (59.82%), Query Frame = 0
Query: 105 IQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKH--------SCANYSFVSYHIPVDHGTPMVTDA---TGVYEGSGQR--------TSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACED-----DPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYV--HSDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPE 954
+ F L+ G+ LD+FYNADV ++++S + Q SLFYHLGVRESF M N+LL + D AL+ +Y+ + Y + G + DA G+ +G Q T L +L +L + S + +E D+R+ RE +G L++ L ++RRLD ++S +++ N+L+S+R++QDY A+++LV+ L+ LP V Q+ + F Y FALNRR++ GDR KA V+ ++ + + PD+ C+CGRI KD F S + D +QA HWYR+ F+V+P+ ++GIN A LL+ AG F S EL+ IGMKL L+ +KG + ++ YWDV + +LA D + + A+E ++KL P WYL S + L FR + FW+ + + +C+ GD + +L+ E +KV +P+ + V ++ +S L + W F I V+ KRD+RC FLY + D Q+ FPS Q F L+ N + + E L F+Y+ E G + VLG+GTYGVVYA RD +T++++A+KE+PE++ QPLHEEI LH +LRHKNIV+Y GS S+ GY KI ME+VPGGSLS+LLRS WGPLK NE+TI++Y++Q+L+GL YLHD IVHRDIKGDNVL+NT+SG++KISDFGTSKRLAG+ P T TF GTLQYMAPE+ID+G RGYG ADIWSLGCTV+EMATG PPF ELGSP+AAMF+VG YK+HP +P LS AQ F+LR FEPDP RA+A LL D F+ + + S+ H +P + SAS S T S+ P+
Sbjct: 94 LPFGTLELGDTAALDAFYNADVVVLEVSSSLVQPSLFYHLGVRESFSMTNNVLLCSQADLPDLQALREDVFQKNSDCVGSYTLIPYVV-TATGRVLCGDAGLLRGLADGLVQAGVGTEALLTPLVGRLARLLEATPTDSCGYFRETIRRDIRQARERFSGPQLRQELARLQRRLDSVELLSPDIIMNLLLSYRDVQDYSAIIELVETLQALPTCDVAEQH-NVCFHYTFALNRRNRPGDRAKALSVLLPLVQLEGSVAPDLYCMCGRIYKDMFFSSGFQDAGHREQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSKELRLIGMKLGCLLARKGCVEKMQYYWDVGFYLGAQILANDPTQVVLAAEQLYKLNAPIWYLVSVMETFLLYQHFRPTPEPPGG--PPRRAHFWLHFLLQSCQPFKTACAQGD--QCLVLVLEMNKVLLPAKLEVRGTDPVSTVTLSLL-----------EPETQDIPSSWTFPVASICGVSASKRDERCCFLYALPPAQDVQLCFPSVGHCQWFCGLIQAWVTNPDSTAPAEEAEGAGEMLEFDYEYTETGERLVLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSLSAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSRSPSSPRHAP---RPSDAPSASPTPSANSTTQSQTFPCPQ 949 HSP 2 Score: 102.064 bits (253), Expect = 2.573e-20 Identity = 93/344 (27.03%), Postives = 149/344 (43.31%), Query Frame = 0
Query: 1112 LLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTPNSPLEEALLASSGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQRS 1455
LL ++S+RR L VL+Q+ A+ + +E L + H + L+ + I NR L + L+ L G + L+ F DAV LR I+PHWMF LD+L+ AV++A+ +L PE+ P + +++E D + PG +P+ P Q LS +R E RL L + +YQ L++ L Q+L+ EE A + + + P PT D+ LV WL+ L+++ G++Q +N T +++ +RDDL +R G RIW+AI QR+
Sbjct: 993 LLHQESKRRAMLAAVLEQELPALAENLHQEQKQEQ-GARLGRNHVEELLRCLGAHIHTPNRRQLAQELRALQGRLRAQGLGPALLHRPLFAFPDAVKQILRKRQIRPHWMFVLDSLLSRAVRAALGVLGPEVEKEAVSPRS-------------------------EELSNEGDSQQS---------PGQQSPLPVEPEQGPAPLMVQ-LSLLRAETDRLREILAGKEREYQALVQRAL----QRLN-------------EE---ARTYVLAPEP-PTALSTDQGLVQWLQELNVDSGTIQMLLNHSFTLHTLLTYATRDDLIYTRIRGGMVCRIWRAILAQRA 1279
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|46576858|sp|O22040.2|ANP1_ARATH (RecName: Full=Mitogen-activated protein kinase kinase kinase ANP1; AltName: Full=Arabidopsis NPK1-related kinase 1) HSP 1 Score: 214.157 bits (544), Expect = 5.584e-57 Identity = 128/303 (42.24%), Postives = 183/303 (60.40%), Query Frame = 0
Query: 652 RKNVLGRGTYGVVYAARDLNTQIKVAVKEV--------PEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTA--TFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGK-KKKLSTRL-----HVSTQLQPEFSRSASMP 938
+ ++GRG +G VY +L++ +AVK+V EK +Q L EE+KL L H NIV+Y G++ ED I++E VPGGS+S+LL K+GP E+ + Y++Q+L GL+YLH+ I+HRDIKG N+LV+ G +K++DFG SK++A L T + GT +MAPEVI Q G+ ADIWS+GCTV+EM TG P+ + AA+F +G K HP +P LS A+ F+L+C + P R TAS LL F+ MGK K+ ST L ++ST L + + + S P
Sbjct: 71 KGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLE-KFGPFP--ESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDN-KGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVI--LQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLKHPFV--MGKHKESASTDLGSVLNNLSTPLPLQINNTKSTP 365
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|46577122|sp|Q9FZ36.1|M3K2_ARATH (RecName: Full=Mitogen-activated protein kinase kinase kinase 2; AltName: Full=Arabidopsis NPK1-related protein kinase 2) HSP 1 Score: 210.305 bits (534), Expect = 7.108e-56 Identity = 117/279 (41.94%), Postives = 172/279 (61.65%), Query Frame = 0
Query: 652 RKNVLGRGTYGVVYAARDLNTQIKVAVKEV--------PEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTA--TFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTR 920
+ ++GRG +G VY +L++ +AVK+V EK +Q L EE+KL L H NIV+Y G++ ED I++E VPGGS+S+LL K+G E+ + Y+ Q+L GL+YLH+ I+HRDIKG N+LV+ G +K++DFG SK++A L + + GT +MAPEVI Q G+ ADIWS+GCTV+EM TG P+ + AA+F +G K HP +P +S A F+L+C + +P R TAS LL F+T GK+K+ +++
Sbjct: 70 KGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLE-KFGAFP--ESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDN-QGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVI--LQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLKHPFVT--GKQKESASK 340
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Match: gi|46576859|sp|O22042.1|M3K3_ARATH (RecName: Full=Mitogen-activated protein kinase kinase kinase 3; AltName: Full=Arabidopsis NPK1-related protein kinase 3) HSP 1 Score: 202.986 bits (515), Expect = 2.515e-53 Identity = 113/275 (41.09%), Postives = 169/275 (61.45%), Query Frame = 0
Query: 652 RKNVLGRGTYGVVYAARDLNTQIKVAVKEV--------PEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCP--DTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKK 916
+ ++G G +G VY +L++ +A+K+V EK G ++ L EE++L L H NIV+Y G++ E I+ME VPGGS+S+LL K+G E I Y+KQ+L GL+YLH+ I+HRDIKG N+LV+ G ++++DFG SK++ L + GT +MAPEVI Q G+ ADIWS+GCTV+EMATG PP+ E AA+ +G K HP +P++LS A+ F+++C +P R +A+ LL F+T GK+++
Sbjct: 70 KGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLE-KFGSFP--EPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILVDN-KGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVIL--QTGHSFSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKAHPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQHPFVT--GKRQE 336
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|1000746905|ref|XP_015596227.1| (PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Cephus cinctus] >gi|1000746907|ref|XP_015596228.1| PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Cephus cinctus] >gi|1000746909|ref|XP_015596229.1| PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Cephus cinctus] >gi|1000746911|ref|XP_015596230.1| PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Cephus cinctus] >gi|1000746913|ref|XP_015596231.1| PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Cephus cinctus]) HSP 1 Score: 1564.28 bits (4049), Expect = 0.000e+0 Identity = 819/1458 (56.17%), Postives = 1011/1458 (69.34%), Query Frame = 0
Query: 28 GGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQI-HQYQE-LSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTPN--------------------SPLEEALLASSGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
G + TDS G+ SD SG HT+ SG RP+M+VVCV+D +L +RK A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQSSLFYHLGVRESFGM++NILL+ D + E T+ LK SC NY+FVSY + V+ G+ P + ATG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L + L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+PN Y PAI +LYAFALNRR+K+GDRE A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL++YWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI RFRK+ + EEQ+F FW+DYFV+A + + GD IRFP+L+ EP+K+ MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMY PS RQ+F+DLVL+MT ++EGM+ DLD + E + FEY+LD+Q ++ +LG+GTYG+V+AARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SEDGYFKI MEQVPGGSLSALLRSKWGPLK NE+TI+YY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+T++ +KK +TRL P+FSRS S+P E+ R L K D ++ T P + QS S + SS +R E +S + T++ F S +G +PSI+ T + D + RRSSSGALLSP+V +I G + G + FYLLKKDSQRR+TL +VL QD A IC W + ++ L H ++LM G+R +I +Q++ + AI LKEELDFD IN + +A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T L+PELGA+L E V VA + STSGVSTVNS+ V+S + +Y+E + ++ EN RLL +LLE Q YQ LL+ L EQR Q+ L+ T N SP +E + ++ HN N D L +WL+ L +++ S+ RF+ E+ T D++ ++RDD+RRL LR G ELRIWKAI R
Sbjct: 23 GISSTDSVGTHSDVSG------HTTISG-----RPRMDVVCVLDLQQPEHLVQRKRALEEVRQACSLVNANMH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSSLFYHLGVRESFGMRENILLYNDMDTEATIRLKLSCGNYTFVSYRV-VECGSCVSTSPAASRATG-EEVIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSRALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTVPNHKNYISTPAICYLYAFALNRRNKEGDRETALRVIEKALEKKENHVPDMLCLCGRINKDKFVESRHTDQESLKNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMVLNNLIGKKGSLSSLKEYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNITLIDRFRKKNEEAEVSSEEQVFSFWMDYFVEATKSEVGDSIRFPLLVLEPTKILMPSYVNVNLGAEEKSIQIWNLCLD-------NMKNNCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYLPSVQCRQRFYDLVLEMTRDQEGMVTDLDAYMTDERMKFEYELDDQNKRIILGKGTYGIVFAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEDGYFKIFMEQVPGGSLSALLRSKWGPLKENESTISYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKSFILRCFEPNPDVRATAAELLEDPFLTEIFSRKKKTTRLAAP----PDFSRSISVPAERLER-LGK----------------------CDKTNNNHIVTAPAIQTSQSDDS--------------GGLTKSSPLR----ERSPAHLLSPISMPTATISF--------NSTIGSTPSIE--------TSETDTAGASMTRRSSSGALLSPEV--EITGQPGQKSGEEQEGFYLLKKDSQRRMTLTRVLSQDEAKICEVWMRSIHQDVGQTVLRMSHLELLMRGLRDYISEQSQDVITTAIRTLKEELDFDSTAINHLHLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITELSPELGANLLGQERV------------------------QSVAEGAEEGSTSGVSTVNSVKS----QKTVDSVDNKYWREYREQMGALKVENMRLLHELLESQKSYQTLLQQALEEQRAQVGALTHLCETINRRTARQESGYNSTIFDGNVVSP-QEGFVPQISVTEHNSSSHN---DNRLTEWLQELWVDETSIDRFLYEEYTLEDILYHVTRDDIRRLNLRGGIELRIWKAILQHR 1362
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|1000746915|ref|XP_015596232.1| (PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X2 [Cephus cinctus]) HSP 1 Score: 1558.5 bits (4034), Expect = 0.000e+0 Identity = 819/1458 (56.17%), Postives = 1009/1458 (69.20%), Query Frame = 0
Query: 28 GGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQI-HQYQE-LSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTPN--------------------SPLEEALLASSGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
G + TDS G+ SD SG HT+ SG RP+M+VVCV+D +L +RK A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQSSLFYHLGVRESFGM++NILL+ D + E T+ LK SC NY+FVSY + V+ G+ P + ATG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L + L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+PN Y PAI +LYAFALNRR+K+GDRE A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL++YWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI RFRK+ + EEQ+F FW+DYFV+A + + GD IRFP+L+ EP+K+ MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMY PS RQ+F+DLVL+MT ++EGM+ DLD + E + FEY+LD+Q ++ +LG+GTYG+V+AARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SEDGYFKI MEQVPGGSLSALLRSKWGPLK NE+TI+YY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+T+ KK +TRL P+FSRS S+P E+ R L K D ++ T P + QS S + SS +R E +S + T++ F S +G +PSI+ T + D + RRSSSGALLSP+V +I G + G + FYLLKKDSQRR+TL +VL QD A IC W + ++ L H ++LM G+R +I +Q++ + AI LKEELDFD IN + +A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T L+PELGA+L E V VA + STSGVSTVNS+ V+S + +Y+E + ++ EN RLL +LLE Q YQ LL+ L EQR Q+ L+ T N SP +E + ++ HN N D L +WL+ L +++ S+ RF+ E+ T D++ ++RDD+RRL LR G ELRIWKAI R
Sbjct: 23 GISSTDSVGTHSDVSG------HTTISG-----RPRMDVVCVLDLQQPEHLVQRKRALEEVRQACSLVNANMH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSSLFYHLGVRESFGMRENILLYNDMDTEATIRLKLSCGNYTFVSYRV-VECGSCVSTSPAASRATG-EEVIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSRALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTVPNHKNYISTPAICYLYAFALNRRNKEGDRETALRVIEKALEKKENHVPDMLCLCGRINKDKFVESRHTDQESLKNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMVLNNLIGKKGSLSSLKEYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNITLIDRFRKKNEEAEVSSEEQVFSFWMDYFVEATKSEVGDSIRFPLLVLEPTKILMPSYVNVNLGAEEKSIQIWNLCLD-------NMKNNCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYLPSVQCRQRFYDLVLEMTRDQEGMVTDLDAYMTDERMKFEYELDDQNKRIILGKGTYGIVFAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEDGYFKIFMEQVPGGSLSALLRSKWGPLKENESTISYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKSFILRCFEPNPDVRATAAELLEDPFLTE----KKKTTRLAAP----PDFSRSISVPAERLER-LGK----------------------CDKTNNNHIVTAPAIQTSQSDDS--------------GGLTKSSPLR----ERSPAHLLSPISMPTATISF--------NSTIGSTPSIE--------TSETDTAGASMTRRSSSGALLSPEV--EITGQPGQKSGEEQEGFYLLKKDSQRRMTLTRVLSQDEAKICEVWMRSIHQDVGQTVLRMSHLELLMRGLRDYISEQSQDVITTAIRTLKEELDFDSTAINHLHLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITELSPELGANLLGQERV------------------------QSVAEGAEEGSTSGVSTVNSVKS----QKTVDSVDNKYWREYREQMGALKVENMRLLHELLESQKSYQTLLQQALEEQRAQVGALTHLCETINRRTARQESGYNSTIFDGNVVSP-QEGFVPQISVTEHNSSSHN---DNRLTEWLQELWVDETSIDRFLYEEYTLEDILYHVTRDDIRRLNLRGGIELRIWKAILQHR 1358
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|805826967|ref|XP_012153339.1| (PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X2 [Megachile rotundata]) HSP 1 Score: 1558.12 bits (4033), Expect = 0.000e+0 Identity = 808/1460 (55.34%), Postives = 1017/1460 (69.66%), Query Frame = 0
Query: 17 NSVTEAEVMEAGGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVL-----------SAHRSTPNSPLEEALLAS--SGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
N+ +++ ++E G + TDS G+ SD SG HT+ SG RP+M+V CV+D +L +R+ A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQS+LFYHLGVRESFGMK+NILL D + E T+ LK SC +Y+FVSY + V+ G+ P T TG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L K L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+P Y PAI +LYAFALNRR+K+GDRE+A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD+ L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL+DYWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI+RFRK+ + PEEQIF FW+DYFV+A + + GD IRFP+L+ EP+K+ MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMYFPS RQ+F+DL+L+MT ++EGM+ DLD + + + FEY+LD+Q ++ +LG+GTYGVVYAARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SEDGYFKI MEQVPGGSLSALLRSKWGPLK NE+TIAYY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+ + K +L P+F RS S+P ++ R SG+ ++ + + Q+S+S S+ + L + SS +R E +S ++ T++ F S +G +PSI+ T + D + RRSSSG LLSP+V ++ G + G + FYLLKKDSQRR+TL +VL QD A IC W + + L H +LM +R +I +QN + AI LKEELDFD IN +++A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T+L+PELGA+L E V P P+ STSGVSTVNS+ + N + ++ ++ EN +LL +L++ Q YQ LL+ L EQR Q++ L + S NS + L S + S++ T+ D+ LV+WL++L +++ +++RF+ E T DV++ +SRDD+RRL LR G ELRIW+AI R
Sbjct: 11 NAASQSNIVE-GISSTDSVGTHSDISG------HTTISG-----RPRMDVACVLDLQQPEHLAQRRRALEEVRQACNLVNANMH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSALFYHLGVRESFGMKENILLHNDMDTETTIRLKLSCGSYTFVSYRV-VECGSCVATNPATTRITGD-EVIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRYLYAFALNRRNKEGDRERALKVIEKALEKKENHVPDMLCLCGRIYKDKFVESRHTDSESLKNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMILNNLIGKKGSLSSLKDYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLINRFRKKNDEAEVSPEEQIFSFWMDYFVEATKSEVGDSIRFPLLVLEPTKILMPSYVNVNLGAEEKSVQIWNLCLD-------NMKNSCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYFPSVQCRQRFYDLILEMTRDQEGMVTDLDAYMTDDRMKFEYELDDQNKRIMLGKGTYGVVYAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEDGYFKIFMEQVPGGSLSALLRSKWGPLKENESTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKSFILRCFEPNPDIRATAAELLEDPFLNEKKKTNRLVA--------PPDFGRSISVPADRLER--------------SGKSD------------KTNNNHAASASPIQTSQSDDSVTYSGGLTK-------SSPLR----ERSPAHLLSPIRMPTATLSF--------NSTIGNTPSIE--------TSETDTSGASMTRRSSSGGLLSPEV--ELGGQPGQKTGEEQEGFYLLKKDSQRRMTLTRVLTQDEAKICEVWMRGIHQAEGQTVLQMTHLVLLMRALRDYIAEQNHEVIVTAIRTLKEELDFDSTAINHLNLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITVLSPELGANLLGQERV------------------------QPGGQGPEEGSTSGVSTVNSVKSQKTGDSVDNKYWKEYR--DQMGSLKMENMKLLQELIDSQKLYQGLLQQILDEQRAQVNTLTRLCENINKRITRQESGYNSSISGNTLQQPVSLIVSNSHSSTDPYADQALVEWLQSLQIDEATIERFMYEQYTLDDVLNHISRDDIRRLNLRGGIELRIWQAIINHR 1357
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|805826961|ref|XP_012153336.1| (PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Megachile rotundata] >gi|805826963|ref|XP_012153337.1| PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Megachile rotundata] >gi|805826965|ref|XP_012153338.1| PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Megachile rotundata]) HSP 1 Score: 1556.58 bits (4029), Expect = 0.000e+0 Identity = 808/1460 (55.34%), Postives = 1017/1460 (69.66%), Query Frame = 0
Query: 17 NSVTEAEVMEAGGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVL-----------SAHRSTPNSPLEEALLAS--SGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
N+ +++ ++E G + TDS G+ SD SG HT+ SG RP+M+V CV+D +L +R+ A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQS+LFYHLGVRESFGMK+NILL D + E T+ LK SC +Y+FVSY + V+ G+ P T TG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L K L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+P Y PAI +LYAFALNRR+K+GDRE+A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD+ L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL+DYWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI+RFRK+ + PEEQIF FW+DYFV+A + + GD IRFP+L+ EP+K+ MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMYFPS RQ+F+DL+L+MT ++EGM+ DLD + + + FEY+LD+Q ++ +LG+GTYGVVYAARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SEDGYFKI MEQVPGGSLSALLRSKWGPLK NE+TIAYY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+ + K +L P+F RS S+P ++ R SG+ ++ + + Q+S+S S+ + L + SS +R E +S ++ T++ F S +G +PSI+ T + D + RRSSSG LLSP+V ++ G + G + FYLLKKDSQRR+TL +VL QD A IC W + + L H +LM +R +I +QN + AI LKEELDFD IN +++A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T+L+PELGA+L E V P P+ STSGVSTVNS+ + N + ++ ++ EN +LL +L++ Q YQ LL+ L EQR Q++ L + S NS + L S + S++ T+ D+ LV+WL++L +++ +++RF+ E T DV++ +SRDD+RRL LR G ELRIW+AI R
Sbjct: 12 NAASQSNIVE-GISSTDSVGTHSDISG------HTTISG-----RPRMDVACVLDLQQPEHLAQRRRALEEVRQACNLVNANMH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSALFYHLGVRESFGMKENILLHNDMDTETTIRLKLSCGSYTFVSYRV-VECGSCVATNPATTRITGD-EVIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRYLYAFALNRRNKEGDRERALKVIEKALEKKENHVPDMLCLCGRIYKDKFVESRHTDSESLKNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMILNNLIGKKGSLSSLKDYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLINRFRKKNDEAEVSPEEQIFSFWMDYFVEATKSEVGDSIRFPLLVLEPTKILMPSYVNVNLGAEEKSVQIWNLCLD-------NMKNSCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYFPSVQCRQRFYDLILEMTRDQEGMVTDLDAYMTDDRMKFEYELDDQNKRIMLGKGTYGVVYAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEDGYFKIFMEQVPGGSLSALLRSKWGPLKENESTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKSFILRCFEPNPDIRATAAELLEDPFLNEKKKTNRLVA--------PPDFGRSISVPADRLER--------------SGKSD------------KTNNNHAASASPIQTSQSDDSVTYSGGLTK-------SSPLR----ERSPAHLLSPIRMPTATLSF--------NSTIGNTPSIE--------TSETDTSGASMTRRSSSGGLLSPEV--ELGGQPGQKTGEEQEGFYLLKKDSQRRMTLTRVLTQDEAKICEVWMRGIHQAEGQTVLQMTHLVLLMRALRDYIAEQNHEVIVTAIRTLKEELDFDSTAINHLNLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITVLSPELGANLLGQERV------------------------QPGGQGPEEGSTSGVSTVNSVKSQKTGDSVDNKYWKEYR--DQMGSLKMENMKLLQELIDSQKLYQGLLQQILDEQRAQVNTLTRLCENINKRITRQESGYNSSISGNTLQQPVSLIVSNSHSSTDPYADQALVEWLQSLQIDEATIERFMYEQYTLDDVLNHISRDDIRRLNLRGGIELRIWQAIINHR 1358
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|987919090|ref|XP_015435616.1| (PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X1 [Dufourea novaeangliae]) HSP 1 Score: 1555.42 bits (4026), Expect = 0.000e+0 Identity = 812/1452 (55.92%), Postives = 1004/1452 (69.15%), Query Frame = 0
Query: 28 GGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTS-SSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLSAHRSTPNSPLEEALLASSGLSSHNPEPTNRPP---------------DEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
G + TDS G+ SD SG HT+ SG RPKM+V CV+D +L +RK A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQS+LFYHLGVRESFGMK+NILL D + E T+ LK SC +Y+FVSY + VD G+ P T TG E + L +LK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L K L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+P Y PAI +LYAFALNRR+K+GDRE+A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD L AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL+DYWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI RFRK+ + PEEQIF FW+DYFV+A + + GD IRFP+L+ EP+K++MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMYFPS RQ+F+DL+L+MT ++EGM+ DLD + + + FEY+ D+Q ++ +LG+GTYGVVYAARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SE+GYFKI MEQVPGGSLSALLRSKWGPLK NE+TIAYY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+ + K +L+ P+FSRS S+P ++ R L ++ + T Q+S+S S+ + L + SS +R ER+ + L + S S L F+ S +G +PSI+ T + D + RRSSSG LLSP+V ++ G + G + FYLLKKDSQRR+TL +VL QD A IC W + + L +LM +R +I +QN + AI LKEELDFD IN +++A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T+L+PELGA+L +G P P+ STSGVSTVNS+ + N + ++ ++ EN RLL +LLE Q YQ LL+ + EQR Q++ L+ R N S SS + +N+PP DE LV+WL+NL +++ S++RF+ E T D++ ++RDD+RRL LR G ELRIW AI R
Sbjct: 22 GISSTDSVGTHSDISG------HTTISG-----RPKMDVACVLDLQQPEHLAQRKRALEEVRQACNLVNANIH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSALFYHLGVRESFGMKENILLHNDVDTETTIRLKLSCGSYTFVSYRV-VDCGSCVATNPATTRITG-EEVIDPKQHLTLRLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRYLYAFALNRRNKEGDRERALKVIEKALEKKENHVPDMLCLCGRIYKDKFVESRHTDEESLNNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMVLNNLIGKKGSLSSLKDYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLIDRFRKKNEEAEVSPEEQIFSFWMDYFVEATKSEVGDSIRFPLLVLEPTKIFMPSYVNVNLGAEEKSVQIWNLCMD-------NMKNSCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYFPSVQCRQRFYDLILEMTRDQEGMVTDLDAYMTDDRMKFEYESDDQNKRIILGKGTYGVVYAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSENGYFKIFMEQVPGGSLSALLRSKWGPLKENESTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKSFILRCFEPNPDIRATAAELLEDPFLNEKKKTNRLAA--------PPDFSRSISVPADRLER--------------------------LGKSDKTNNNHIVSATPIQTSQSDDSVTYSGGLTK-------SSPLR--------ERSPAHLLSPISMPSATLSFN-----STIGNTPSIE--------TTESDTTGASMTRRSSSGGLLSPEV--ELGGQPGQKTGEEQEGFYLLKKDSQRRMTLTRVLTQDEAKICEVWMRGIHQAEGQTVLQMSQLVLLMRALRDYIAEQNHEVIVTAIRTLKEELDFDSTAINHLNLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITVLSPELGANL------------------------LGQERAQPGGQGPEEGSTSGVSTVNSVKSQKTGDSIDNKYWKEYR--DQMGDLKMENMRLLQELLESQKAYQVLLQQAVEEQRTQVNTLT--RLCENINRTTMRQESGYHSSVSGNVSNQPPPTIVSDMSSDTISCTDEALVEWLQNLQIDEMSIERFIYEQYTLEDILCHITRDDIRRLNLRGGTELRIWLAILKHR 1358
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|925683689|gb|KOX80267.1| (Mitogen-activated protein kinase kinase kinase 15 [Melipona quadrifasciata]) HSP 1 Score: 1554.65 bits (4024), Expect = 0.000e+0 Identity = 808/1460 (55.34%), Postives = 1011/1460 (69.25%), Query Frame = 0
Query: 18 SVTEAEVMEAGGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQ-ELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLS-----------AHRSTPNSPLEEALLAS--SGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
+V + G + TDS G+ SD SG HT+ SG RP+M+V CV+D +L +R+ A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQS+LFYHLGVRESFGMK+NILL D + E T+ +K SC NY+FVSY + V+ G+ P T TG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L K L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+P Y PAI +LYAFALNRR+K+GDRE+A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL+DYWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI RFRK+ + PEEQIF FW+DYFV+A + + GD IRFP+L+ EP+K+ MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMYFPS RQ+F+DL+L+MT ++EGM+ADLD + + + FEY+LD+Q ++ +LG+GTYG+VYAARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SE+GYFKI MEQVPGGSLSALLRSKWGPLK NE+TIAYY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+ + KK S RL P+FSRS S+P ++ R L SS + + Q+S+S S + SS +R E +S ++ T++ F S +G +PSI+ T + D + RRSSSG LLSP+V ++ G + G + FYLLKKDSQRR+TL +VL QD A IC W + + L H +LM +R +I +QN+ + AI LKEELDFD IN +++A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T+L+PELGA+L +G + P+ STSGVSTVNS+ + N +YQ ++ ++ EN RLL +L+E Q YQ LL+ L EQR Q++ L+ S NS + + S + S+ P T D+ LV+WL++L +++ S++RF+ E T ++++ ++R+D+RRL L+ G ELRIW+AI R
Sbjct: 12 AVAAQSTIAEGISSTDSIGTHSDISG------HTTISG-----RPRMDVACVLDLQQSEHLAQRRRALEEVRQACNLVNANMH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSALFYHLGVRESFGMKENILLHNDIDTETTIRIKLSCGNYTFVSYRV-VECGSCVATNPATTRITG-EEVIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRYLYAFALNRRNKEGDRERALKVIQKALEKKENHVPDMLCLCGRIYKDKFVESRHTDEESLKNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMVLNNLIGKKGSLSSLKDYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLIDRFRKKNEEAEISPEEQIFTFWMDYFVEATKSEVGDSIRFPLLVLEPTKILMPSYVNVNLGAEEKSVQIWNLCLD-------NMKNSCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYFPSVQCRQRFYDLILEMTRDQEGMVADLDAYMTDDRMKFEYELDDQNKRIMLGKGTYGIVYAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEEGYFKIFMEQVPGGSLSALLRSKWGPLKENESTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKNFILRCFEPNPDIRATAAELLEDPFLNE----KKKSNRLAAV----PDFSRSISVPADRLER--------------------------LGKSDKSSNNQIVSASPIQTSQSDDS-----------GGLTKSSPLR----ERSPAHLLSPIRMPTATLSF--------NSAIGNTPSIE--------TSESDTAGASMTRRSSSGGLLSPEV--ELGGQSGHKTGEEQEGFYLLKKDSQRRMTLTRVLTQDEAKICEVWMRGIHQAEGQTVLQMNHLILLMRALRDYIAEQNQEVIVTAIRTLKEELDFDSTAINHLNLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITVLSPELGANL------------------------LGQERMQSSGQGPEEGSTSGVSTVNSVKSQKTGDSLDNKYW---KEYQDQMGALKMENLRLLQELIENQKSYQTLLQQVLEEQRGQVNALTRLCENINRRTIRQESGYNSSVSGNTVQQPISLIVSNIPSSTTSCNDQALVEWLQSLQIDEMSIERFLYEQYTLDNILNHVTREDIRRLNLKGGTELRIWQAILKHR 1354
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|808141815|ref|XP_012172400.1| (mitogen-activated protein kinase kinase kinase 15 isoform X1 [Bombus terrestris] >gi|808141817|ref|XP_012172401.1| mitogen-activated protein kinase kinase kinase 15 isoform X1 [Bombus terrestris]) HSP 1 Score: 1554.27 bits (4023), Expect = 0.000e+0 Identity = 808/1459 (55.38%), Postives = 1015/1459 (69.57%), Query Frame = 0
Query: 18 SVTEAEVMEAGGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLS-----------AHRSTPNSPLEEALLAS--SGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
+VT + G + TDS G+ SD SG HT+ SG RP+M+V CV+D +L +R+ A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQS+LFYHLGVRESFGMK+NILL D + E T+ +K SC NY+FVSY + V+ G+ P T TG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L K L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+P Y PAI +LYAFALNRR+K+GDRE+A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL+DYWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI RFRK+ + PEEQIF FW+DYFV+A + + GD IRFP+L+ EP+K+ MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMYFPS RQ+F+DL+L+MT ++EGM+ DLD + + + FEY+LD+Q ++ +LG+GTYG+VYAARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SE+GYFKI MEQVPGGSLSALLRSKWGPLK NE+TIAYY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+ + K +L+ P+FSRS S+P ++ R L ++ + + Q+S+S S+ + L + SS +R E +S ++ T++ F S +G +PSI+ T + D + RRSSSG LLSP+V ++ G + G + FYLLKKDSQRR+TL +VL QD A IC W + + L H +LM +R +I +QN+ + AI LKEELDFD IN +++A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T+L+PELGA+L E V ++G D G P+ STSGVSTVNS+ + N + ++ ++ EN RLL +L+E Q YQ LL+ L EQR Q++ L+ S NS + ++ S + S P T D+ L++WL++L +++ S++RF+ E T DV++ ++R+D+RRL LR G ELRIW+AI R
Sbjct: 12 TVTAQSTIAEGISSTDSIGTYSDISG------HTTISG-----RPRMDVACVLDLQQPEHLAQRRRALEEVRQACNLVNANMH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSALFYHLGVRESFGMKENILLHNDVDTETTIRIKLSCGNYTFVSYRV-VECGSCVATNPATTRITG-EEVIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRYLYAFALNRRNKEGDRERALKVIEKALEKKENHVPDMLCLCGRIYKDKFVESRHTDEESLKNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMVLNNLIGKKGSLSSLKDYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLIDRFRKKNEEAEVSPEEQIFSFWMDYFVEATKSEVGDSIRFPLLVLEPTKILMPSYVNVNLGAEEKSVQIWNLCLD-------NMKNSCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYFPSVQCRQRFYDLILEMTRDQEGMVTDLDAYMTDDRMKFEYELDDQNKRIMLGKGTYGIVYAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEEGYFKIFMEQVPGGSLSALLRSKWGPLKENESTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKNFILRCFEPNPDIRATAAELLEDPFLNEKKKTNRLAA--------VPDFSRSISVPADRLER--------------------------LGKSDKTNNNHIVSASPIQTSQSDDSVTYSGGLTK-------SSPLR----ERSPAHLLSPIRMPTATLSF--------NSTIGNTPSIE--------TSESDTAGASMTRRSSSGGLLSPEV--ELGGQPGQKTGEEQEGFYLLKKDSQRRMTLTRVLNQDEAKICEVWMRGICQAEGQTVLQMNHLILLMRALRDYIVEQNQGVIVTAIRTLKEELDFDSIAINHLNLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITVLSPELGANLLGQERV----QSG--------DQG------------PEEGSTSGVSTVNSVKSQKTGDSLDNKYWKEYR--DQMGALKMENLRLLQELIESQKSYQALLQQVLEEQRTQVNALTRLCEGINRRTMRQESGYNSSISGNIVQQPISLVISDAPSSTTSCSDQALIEWLQSLQVDEMSIERFLYEQYTLDDVLNHVTREDIRRLNLRGGIELRIWQAILKYR 1358
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|815894831|ref|XP_012240193.1| (mitogen-activated protein kinase kinase kinase 15 isoform X2 [Bombus impatiens] >gi|815894833|ref|XP_012240196.1| mitogen-activated protein kinase kinase kinase 15 isoform X2 [Bombus impatiens]) HSP 1 Score: 1552.34 bits (4018), Expect = 0.000e+0 Identity = 807/1459 (55.31%), Postives = 1014/1459 (69.50%), Query Frame = 0
Query: 18 SVTEAEVMEAGGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLS-----------AHRSTPNSPLEEALLAS--SGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
+V + G + TDS G+ SD SG HT+ SG RP+M+V CV+D +L +R+ A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQS+LFYHLGVRESFGMK+NILL D + E T+ +K SC NY+FVSY + V+ G+ P T TG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L K L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+P Y PAI +LYAFALNRR+K+GDRE+A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL+DYWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI RFRK+ + PEEQIF FW+DYFV+A + + GD IRFP+L+ EP+K+ MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMYFPS RQ+F+DL+L+MT ++EGM+ DLD + + + FEY+LD+Q ++ +LG+GTYG+VYAARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SE+GYFKI MEQVPGGSLSALLRSKWGPLK NE+TIAYY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+ + K +L+ P+FSRS S+P ++ R L ++ + + Q+S+S S+ + L + SS +R E +S ++ T++ F S +G +PSI+ T + D + RRSSSG LLSP+V ++ G + G + FYLLKKDSQRR+TL +VL QD A IC W + + L H +LM +R +I +QN+ + AI LKEELDFD IN +++A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T+L+PELGA+L E V ++G D G P+ STSGVSTVNS+ + N + ++ ++ EN RLL +L+E Q YQ LL+ L EQR Q++ L+ S NS + ++ S + S P T D+ L++WL++L +++ S++RF+ E T DV++ ++R+D+RRL LR G ELRIW+AI R
Sbjct: 12 TVAAQSTIAEGISSTDSIGTYSDISG------HTTISG-----RPRMDVACVLDLQQPEHLAQRRRALEEVRQACNLVNANMH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSALFYHLGVRESFGMKENILLHNDVDTETTIRIKLSCGNYTFVSYRV-VECGSCVATNPATTRITG-EEVIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRYLYAFALNRRNKEGDRERALKVIEKALEKKENHVPDMLCLCGRIYKDKFVESRHTDEESLKNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMVLNNLIGKKGSLSSLKDYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLIDRFRKKNEEAEVSPEEQIFSFWMDYFVEATKSEVGDSIRFPLLVLEPTKILMPSYVNVNLGAEEKSVQIWNLCLD-------NMKNSCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYFPSVQCRQRFYDLILEMTRDQEGMVTDLDAYMTDDRMKFEYELDDQNKRIMLGKGTYGIVYAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEEGYFKIFMEQVPGGSLSALLRSKWGPLKENESTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKNFILRCFEPNPDIRATAAELLEDPFLNEKKKTNRLAA--------VPDFSRSISVPADRLER--------------------------LGKSDKTNNNHIVSASPIQTSQSDDSVTYSGGLTK-------SSPLR----ERSPAHLLSPIRMPTATLSF--------NSTIGNTPSIE--------TSESDTAGASMTRRSSSGGLLSPEV--ELGGQPGQKTGEEQEGFYLLKKDSQRRMTLTRVLNQDEAKICEVWMRGICQAEGQTVLQMNHLILLMRALRDYIVEQNQGVIVTAIRTLKEELDFDSIAINHLNLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITVLSPELGANLLGQERV----QSG--------DQG------------PEEGSTSGVSTVNSVKSQKTGDSLDNKYWKEYR--DQMGALKMENLRLLQELIESQKSYQALLQQVLEEQRTQVNALTRLCEGINRRTMRQESGYNSSISGNIVQQPISLVISDAPSSTTSCSDQALIEWLQSLQVDEMSIERFLYEQYTLDDVLNHVTREDIRRLNLRGGIELRIWQAILKYR 1358
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|759057068|ref|XP_011337778.1| (PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X2 [Ooceraea biroi] >gi|607360555|gb|EZA54883.1| Mitogen-activated protein kinase kinase kinase [Ooceraea biroi]) HSP 1 Score: 1551.57 bits (4016), Expect = 0.000e+0 Identity = 818/1488 (54.97%), Postives = 1013/1488 (68.08%), Query Frame = 0
Query: 1 MPSAVDNMSQSSTNLNNSVTEAEVMEAGGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVLS-----AHR---------------STPNSPLEEALLASSGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQRSREIR 1459
MPS +M + + + E G + TDS G++SD SG TT+ RP+M+V CV+D +L +RK A +E + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVAI+DLS+ +QQS+LFYHLGVRESFGMK+NILL+ D + E T+ LK SC +Y+FVSY + G+ P T TG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L K L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+P Y PAI +LYAFALNRR+K+GDRE+A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL+DYWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI RFRKR + PEEQIF FW+DYFV+A + + GD IRFPIL+ EP+K+ MPSYV VN+ EEKS+QI N+C + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMY PS RQ+F+DL+L+MT ++EGM+ DLD + + + FEY+LD+Q ++ VLG+GTYGVVYAARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SEDGYFKI MEQVPGGSLSALLRSKWGPLK NE+TI+YY+KQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TFAGTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+ + KKK SR + P FSR++S + E + + + + ++ ++ + S D +T+ SS +R E +S + T++ F S +G +PSI+ T + D + RRSSSG LLSP+V ++ G + G + FYLLKKDSQRR+TL +VL QD A IC W + + L H +LM G+R +I +QN+ + AI LKEELDFD IN + +A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T+L+PELGA+L E P P+ STSGVSTVNS+ + N + ++ ++ EN RLL +L+E Q YQ LL+ L EQR Q++ L+ HR STP P+ S ++ + ++ D LVDWLRNL +++ S+ F+ E+ T DV+ ++RDDLRRL LR G ELRIW+AI R REIR
Sbjct: 1 MPSICGDMVDMTVASQSGIGE------GISSTDSVGTQSDTSGYTTVPG-----------RPRMDVACVLDLQQSEHLAQRKKALDEVRQACNLVNANIH---HIQFEKLDFGETNVLDTFYNADVAIVDLSIQLQQSALFYHLGVRESFGMKENILLYNDVDTEATIRLKLSCGSYTFVSYRVVESCGSCVATNPATTRITG-EEAIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRYLYAFALNRRNKEGDRERALKVIEKALEKKENHVPDMLCLCGRIYKDKFVESRHTDQESLRNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMVLNNLIGKKGSLSSLKDYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLIDRFRKRNEEAEVAPEEQIFGFWMDYFVEATKPEVGDSIRFPILVLEPTKILMPSYVNVNLGAEEKSIQIWNMCLD-------NMRNNCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYLPSVQCRQRFYDLILEMTRDQEGMVTDLDAYMTDDRMKFEYELDDQNKRIVLGKGTYGVVYAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEDGYFKIFMEQVPGGSLSALLRSKWGPLKENESTISYYTKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFAGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKSFILRCFEPNPDVRATAAELLEDPFLNE--KKKS---------------SRLVAPP--DFSRSISVPADRLERLGKCDKTN-NNHIVAAAAMQMSQSDDSGGLTK-------------------------SSPLR----ERSPAHLLSPISMPTATLSF--------NSTIGNTPSIE--------TSESDTTGASITRRSSSGGLLSPEV--ELGGQPGQKSGEEQEGFYLLKKDSQRRMTLTRVLNQDEAKICEVWMRGIHQAEGQTVLQMSHLVLLMRGLRDYIAEQNQEVIVTAIRTLKEELDFDSTAINHLHLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITVLSPELGANLLGQER-------------------------QPGGQGPEEGSTSGVSTVNSVKSQKTADSIDNKYWKEYR--DQMGALKMENMRLLQELIESQKSYQTLLQQALEEQRAQVNTLTHLCENIHRRAARQESGYNSDIPGSTPQQPV------SLAITDTHHSTASQYSDMALVDWLRNLQVDEASIDMFLYEEYTLEDVLQHVTRDDLRRLNLRGGIELRIWQAI--LRHREIR 1358
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Match: gi|805826969|ref|XP_012153340.1| (PREDICTED: mitogen-activated protein kinase kinase kinase 15 isoform X3 [Megachile rotundata]) HSP 1 Score: 1551.18 bits (4015), Expect = 0.000e+0 Identity = 807/1460 (55.27%), Postives = 1014/1460 (69.45%), Query Frame = 0
Query: 17 NSVTEAEVMEAGGAQTDSFGSRSDNSGKTTMSVHTSASGLQLSLRPKMEVVCVIDTHAHANLPERKLAFEEAKFACGLMISPLHEVVHIQFEKLDFGEANVLDSFYNADVAIIDLSVVVQQSSLFYHLGVRESFGMKQNILLFLDTNGEDTLALKHSCANYSFVSYHIPVDHGT-----PMVTDATGVYEGSGQRTSLATKLKQLFQEMEIQSKVHMKEKFLADLRKCRESLTGESLKKGLHNMRRRLDDPNVISGEVVHNVLISFREIQDYDAMVQLVQDLKTLPNRGVYTQNPAIIFLYAFALNRRHKDGDREKAYQVITKALERKENEVPDIICLCGRICKDKFVESEYTDTIMLQQAIHWYRRGFEVQPNEYAGINLATLLVVAGNDFGTSPELQRIGMKLNNLIGKKGSLSSLEDYWDVATFFEISVLAEDYGKAIQASECMFKLKPPNWYLKSTIGNIKLISRFRKRTGSDHLHPEEQIFDFWVDYFVDACEDDPGDLIRFPILIWEPSKVYMPSYVTVNIDIEEKSLQISNLCQQCVGHISISASNKCNKIHEWLFTAPMIKTVTIYKRDDRCLFLYVH--SDDFQMYFPSESWRQKFFDLVLKMTANEEGMIADLDQAINSETLAFEYDLDEQGRKNVLGRGTYGVVYAARDLNTQIKVAVKEVPEKNLGDVQPLHEEIKLHSQLRHKNIVQYHGSLSEDGYFKIIMEQVPGGSLSALLRSKWGPLKGNEATIAYYSKQMLEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPDTATFAGTLQYMAPEVIDRGQRGYGAPADIWSLGCTVVEMATGLPPFIELGSPEAAMFKVGYYKMHPEVPQELSERAQQFILRCFEPDPEKRATASLLLDDQFITDMGKKKKLSTRLHVSTQLQPEFSRSASMPVEKFSRTLSKMVNSPEDIAESGEGSLSSRKISLDSGWHSSQDTRPCVTRWQSSKSWSSMRHQRHLNRFFAQVRTSSQVRVQHQEFQSERTISSLKTRTSSSGFLRFSHYRSGSNVGVSPSIDVQSHVLTPTDQLDGDPLLLARRSSSGALLSPDVLEQIKSVDGMEGG--NDNFYLLKKDSQRRLTLVKVLQQDRAAICRQWNLLMSKENPDFCLSQRHFQILMDGIRGFIPDQNRIALEAAISKLKEELDFDGAKINQISIALYLFQDAVNSSLRSHSIKPHWMFALDNLVRSAVQSAVTILTPELGAHLADPEMVLDDLRAGALPDPTRDDLGVGHIPLDPVAHEPDGASTSGVSTVNSIPGGLNPMAHVNSAHPQIHQYQELSQVREENSRLLSQLLELQHKYQHLLRHNLVEQRQQLDVL-----------SAHRSTPNSPLEEALLAS--SGLSSHNPEPTNRPPDEELVDWLRNLDLNDGSVQRFVNEDLTYSDVMSLMSRDDLRRLGLRAGPELRIWKAIQTQR 1454
N+ +++ ++E G + TDS G+ SD SG HT+ SG RP+M+V CV+D +L +R+ A EE + AC L+ + +H HIQFEKLDFGE NVLD+FYNADVA++DLS+ +QQS+LFYHLGVRESFGMK+NILL D + E T+ LK SC +Y+FVSY + V+ G+ P T TG E + L KLK+LFQ++E+QSK HMKEKFLADLRK RE+ +GE L K L+NMR+RLDDPNV+SGEVV NVLISFREIQDYDAMVQLV DL+T+P Y PAI +LYAFALNRR+K+GDRE+A +VI KALE+KEN VPD++CLCGRI KDKFVES +TD+ L+ AIHWYR+GFEVQPNEYAGINLATLLV+AGN+F S ELQ IGM LNNLIGKKGSLSSL+DYWDVATFFEISVLAEDY KAIQA+ECMFKLKPPNWYLKSTIGNI LI+RFRK+ + PEEQIF FW+DYFV+A + + GD IRFP+L+ EP+K+ MPSYV VN+ EEKS+QI NLC + N C ++H+WLFTA MI++V++YKRD+RCLFLYVH SDDFQMYFPS RQ+F+DL+L+MT ++EGM+ DLD + + + FEY+LD+Q ++ +LG+GTYGVVYAARDLNTQ+++AVKE+ E+NLGDVQPLHEEIKLHSQLRH+NIVQY GS+SEDGYFKI MEQVPGGSLSALLRSKWGPLK NE+TIAYY+KQ+LEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFG SKRLAGLCP T TF GTLQYMAPEVID+GQRGYGAPADIWSLGCT+VEMATG PPFIELGSP+AA+FKVGYYK+HPE+P ELSERA+ FILRCFEP+P+ RATA+ LL+D F+ + K +L P+F RS S+P ++ R SG+ ++ + + Q+S+S S + SS +R E +S ++ T++ F S +G +PSI+ T + D + RRSSSG LLSP+V ++ G + G + FYLLKKDSQRR+TL +VL QD A IC W + + L H +LM +R +I +QN + AI LKEELDFD IN +++A+YLFQ AVN LR HSIKPHWMFALDNLVR+AVQ+A+T+L+PELGA+L E V P P+ STSGVSTVNS+ + N + ++ ++ EN +LL +L++ Q YQ LL+ L EQR Q++ L + S NS + L S + S++ T+ D+ LV+WL++L +++ +++RF+ E T DV++ +SRDD+RRL LR G ELRIW+AI R
Sbjct: 12 NAASQSNIVE-GISSTDSVGTHSDISG------HTTISG-----RPRMDVACVLDLQQPEHLAQRRRALEEVRQACNLVNANMH---HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSALFYHLGVRESFGMKENILLHNDMDTETTIRLKLSCGSYTFVSYRV-VECGSCVATNPATTRITGD-EVIDPKQHLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSGEVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRYLYAFALNRRNKEGDRERALKVIEKALEKKENHVPDMLCLCGRIYKDKFVESRHTDSESLKNAIHWYRKGFEVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMILNNLIGKKGSLSSLKDYWDVATFFEISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLINRFRKKNDEAEVSPEEQIFSFWMDYFVEATKSEVGDSIRFPLLVLEPTKILMPSYVNVNLGAEEKSVQIWNLCLD-------NMKNSCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYFPSVQCRQRFYDLILEMTRDQEGMVTDLDAYMTDDRMKFEYELDDQNKRIMLGKGTYGVVYAARDLNTQVRIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGSVSEDGYFKIFMEQVPGGSLSALLRSKWGPLKENESTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPQAAVFKVGYYKIHPEIPSELSERAKSFILRCFEPNPDIRATAAELLEDPFLNEKKKTNRLVA--------PPDFGRSISVPADRLER--------------SGKSD------------KTNNNHAASASPIQTSQSDDS-----------GGLTKSSPLR----ERSPAHLLSPIRMPTATLSF--------NSTIGNTPSIE--------TSETDTSGASMTRRSSSGGLLSPEV--ELGGQPGQKTGEEQEGFYLLKKDSQRRMTLTRVLTQDEAKICEVWMRGIHQAEGQTVLQMTHLVLLMRALRDYIAEQNHEVIVTAIRTLKEELDFDSTAINHLNLAIYLFQTAVNEVLRMHSIKPHWMFALDNLVRNAVQAAITVLSPELGANLLGQERV------------------------QPGGQGPEEGSTSGVSTVNSVKSQKTGDSVDNKYWKEYR--DQMGSLKMENMKLLQELIDSQKLYQGLLQQILDEQRAQVNTLTRLCENINKRITRQESGYNSSISGNTLQQPVSLIVSNSHSSTDPYADQALVEWLQSLQIDEATIERFMYEQYTLDDVLNHISRDDIRRLNLRGGIELRIWQAIINHR 1354 The following BLAST results are available for this feature:
BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 25
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BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of mitogen-activated protein kinase kinase kinase 15 isoform x4 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold866_size86999:67129..84753+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>snap_masked-scaffold866_size86999-processed-gene-0.5 ID=snap_masked-scaffold866_size86999-processed-gene-0.5|Name=mitogen-activated protein kinase kinase kinase 15 isoform x4|organism=Tigriopus kingsejongensis|type=gene|length=17625bp|location=Sequence derived from alignment at scaffold866_size86999:67129..84753+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'mitogen-activated protein kinase kinase kinase 15 isoform x4' has the following synonyms
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