BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000007768 (supercontig:LSalAtl2s:LSalAtl2s453:563174:567050:-1 gene:EMLSAG00000007768 transcript:EMLSAT00000007768 description:"maker-LSalAtl2s453-snap-gene-4.55")

HSP 1 Score: 360.147 bits (923), Expect = 1.612e-112
Identity = 210/567 (37.04%), Postives = 318/567 (56.08%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTV-QIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDS------MRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRA--FQLEHSGTGPLTYF----AESNADKWINALQDA 785
            +A+E++ SE  YVN L L+N DFR F++++I++    +P  E   I +   E+   N DLL+DF  R+ NW    KIADI V KG FL +Y++Y++ FP  S+ Y+ CL++YP+FRELV  F+ ++ C  L I   +L+P+QRLP+YKL  ERYV        DY  +  A  I+ + AD +N  ++  D F++++ LQ R++  +L+Q DR L KEG + K +RN +D  Y+VL +D+L+Y   S  ++     N  L++ YKIPL  L V  +AD  +    DF I SSVRS  LRA +  EK+EW+++I  A      ++++F    +   +   +  + +    +  PVWIPD  V+MCQ C  +F  +  RRHHCR CG V C  CS N APL+Y  Y+  RVCD+CF  +K  Y   D+      + L+R     +  S   +PN  +  K    G    G+L  +   +GKW+K+WF LK+  L+ +KAS D   + T  +LG ++ +  E   +L +   NG +  FQL H+G    +       E    KW+ ALQ+A
Sbjct:  256 IAREIMTSEEAYVNNLKLLNVDFRAFVSKEIDD---AIPPCELNKILSYFPELQLLNSDLLNDFTSRIRNWDSNPKIADIMVIKGKFLLIYASYIKEFPRNSQFYQECLKKYPKFRELVLAFQLKKECRNLKIEHLMLEPIQRLPRYKLLFERYVKNLPVGDPDYEVSLEALEIILKIADKANTELKEYDEFKKMLNLQSRVNESDLIQPDRELFKEGELLKISRNSVDPRYIVLLSDILLYTX-SYSILAGEPANTNLRIHYKIPLIKLKVDDLADEIDAEETDFQIISSVRSFVLRANSLEEKIEWMKAINDAATSLRTKRSTFD---LQKSKEIPEEEEKEIILGETAPVWIPDKKVSMCQKCAIEFS-VLTRRHHCRGCGIVTCFYCSDNRAPLKYLNYKSDRVCDECFDSIKEEYYYQDAKANSQYLSLFRKREEHKSGSLRTVPN-RLKMKANAEGAXAAGYLRKRVVKSGKWKKSWFVLKDNVLYAYKASSDTVAIDTFPVLGLEVEVISEKIEDLNNE-PNGSSVVFQLIHAGLQKYSLCFKTENEQQLQKWVKALQEA 812          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000004783 (supercontig:LSalAtl2s:LSalAtl2s251:1599936:1642958:1 gene:EMLSAG00000004783 transcript:EMLSAT00000004783 description:"maker-LSalAtl2s251-augustus-gene-16.6")

HSP 1 Score: 329.331 bits (843), Expect = 2.878e-97
Identity = 187/515 (36.31%), Postives = 289/515 (56.12%), Query Frame = 0

Query:  221 PSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDN--DFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMR-----------LYRGLFNGRKNSFVQLPN-----------PSVLR-KGRENGFEVNGHLHFKSTTTGKWRKNWF 708
            P+   +  +  F +A+E++ SER +V+ L L++ + + FI  K      ++P  +   IF+N+ E+   N+DLL DF++R++NW    KIAD+ VKKGPFLKLY+TY++ F D +  ++ CL +Y +F ++V+EFES E C  L I  ++LKPVQRLPQYKL LE Y+    P                             D FR++++LQ R+   EL++  R LIKEG ++K +R G+   Y +L +D+L+YA  S G  +   ++  L+V Y IPL+TL+V++  +   Y  +F++ S VRSC LRA +  E+ EWIE++   +E++  R+A+F      F   S+D   +  D  GN C PVWIPD  VTMCQ C  +F  L  RRHH R CG+V+C +CS N+APLRY  +   RVCD+CF  L+      ++++           L R   +G  +S   LP            P  L+ +    G +++G+L  +   +GKW++ W+
Sbjct:  838 PNPGRRKKKQVFYIAREIMTSERVFVDVLHLLDVELKDFIDSKRRNGKKLIPEGDLNKIFSNLSELHALNKDLLSDFEERIQNWETFPKIADVIVKKGPFLKLYTTYIREFSDVNMHFDECLMKYQKFAKVVKEFESLERCRNLKIKHFMLKPVQRLPQYKLLLEDYLKHLDP-----------------------------DKFRRMLKLQSRLGDQELIRPGRELIKEGELQKISRKGIGPRYFILLSDVLLYATYSSGNRS---DSSGLRVSYSIPLNTLSVRVLPH---YETEFSVSSPVRSCTLRASSVSERNEWIEALNHGIEEHRNRKATF------FPGSSSDIDCDQLDVVGN-CAPVWIPDRRVTMCQNCTVEFSVLV-RRHHXRACGKVVCASCSGNKAPLRYKGFEVGRVCDECFDSLERELGHVENLKHRFKKRHLSNNLERQTGSGLISSGPGLPGSYPTHPHGRYVPGRLKVRAVGEGAQMSGYLKRRIQKSGKWKRMWY 1309          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000002673 (supercontig:LSalAtl2s:LSalAtl2s154:239531:245063:1 gene:EMLSAG00000002673 transcript:EMLSAT00000002673 description:"maker-LSalAtl2s154-snap-gene-2.5")

HSP 1 Score: 187.193 bits (474), Expect = 3.769e-50
Identity = 123/432 (28.47%), Postives = 219/432 (50.69%), Query Frame = 0

Query:  231 AFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRD-LLHDFKDRVENWRG---KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMD-MHELVQADRGLIKEGPIKKQNRNGLDD---------IYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKS 648
            A  +A+ELL +E +YV  L L++  F   + ++     N+   +    +F N+K I +F+ + LL   ++R+ENW+G   +I DIFVK  PF K+Y+ Y++NF  A         +  +F  ++ +  S   CG L +  ++L P+QR+P+Y++ L+ Y+ K   +S D  D+ +A  +VS AA H+N+ ++  + F++L+ +Q  +    +LV   R L+KEG I K +    D            L+LC+  LI  R+ P          P ++  +  + ++ V   DN       F I+ + +S  L  +T  EK +W+E++ + +++  QR++S        K    +            P  +  D+++ C  C   F  + +++H+CR CG V+C  CS  + PL + + +P RVC  CF +L S
Sbjct:   92 AHRIAKELLSTEEQYVRVLYLIDQVFHTRVDQE-NRTQNLFSADVLPQMFANIKSIYKFHAEFLLPQLRERMENWKGSNQRIGDIFVKFSPFFKMYTEYVKNFGSAIHLINHIYNKNSKFAGIMDDIHSMPECGNLSLQHHMLTPIQRIPRYEMLLKDYLKKLPEDSDDREDSEKALHLVSTAAAHANDAMKRIEKFKKLLEVQECLSGTVDLVNPTRELVKEGKIVKISARSGDHQERYLFLFSDLLLLCSPRLITNRVIPS------GTAPFRLRARFDVESIQVLEGDNLVT-ANSFYIRDNHKSVELYTQTLEEKEDWLEALFQTIKELYQRKSSLRIGRETLKPLDCEIGRKQ-------PHLLKLDTISKCMDCGHPF-SMMRKKHNCRACGIVICAKCSGQKFPLTFEENKPCRVCKTCFNLLNS 507          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000003617 (supercontig:LSalAtl2s:LSalAtl2s1983:17358:19185:-1 gene:EMLSAG00000003617 transcript:EMLSAT00000003617 description:"maker-LSalAtl2s1983-augustus-gene-0.7")

HSP 1 Score: 101.679 bits (252), Expect = 1.240e-22
Identity = 69/247 (27.94%), Postives = 128/247 (51.82%), Query Frame = 0

Query:  236 QELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRM--DMHELVQADRGLIKEGPIKKQNR----NGLDDIYLVLCTDLLIYARI 476
            +EL++SE+ Y+  L ++   F   +  K  +        +F+ +F ++  I + N +LL    + +E+ + +I  +F++  P+LK YSTY   F    K  E   E    F  ++   ESR     L ++S L+ P+QR+P+YKL LE  +  +  +  D LD T+A L +   A + +  I   +N R+ + +Q+ +  ++ ++V+  R L+K G + K  R    NG+  ++ VL  D L+Y ++
Sbjct:   52 KELVESEKSYLKHLEILENFFSEPLKSKFPK------YSDFKSVFGDIPTIRKVNAELL----EAIESSKDRIGLVFLELAPYLKFYSTYANEFASNVKLVEKLTEENKEFGRVLNSRESRPEALGLKLNSLLITPIQRIPRYKLLLEDLLKNTPTQHPDRLDLTKALLEIDSVARYIDTQIGEHENARRTLDIQKSLVKNLPKIVKPGRILLKTGLLMKVPRSGSGNGVQRLF-VLFNDTLMYCKV 287          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000009590 (supercontig:LSalAtl2s:LSalAtl2s617:108630:110337:-1 gene:EMLSAG00000009590 transcript:EMLSAT00000009590 description:"augustus_masked-LSalAtl2s617-processed-gene-1.3")

HSP 1 Score: 77.411 bits (189), Expect = 2.991e-15
Identity = 59/215 (27.44%), Postives = 91/215 (42.33%), Query Frame = 0

Query:  438 LVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMED---NSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSN 649
            L    R L+ EG + K  R         L  D+++Y  I   +IN    N        IPL  + +Q  ++  ++   + I +  +S  + A T  EK +W+  I++ ++D   +S ++ S   A V                      WIPD     C VC      +  RRHHCR CG V+C +CS+N   +     +P RVCD C+  L  N
Sbjct:   31 LAVKGRVLVGEGILTKACRKKPKPRQFFLFDDIVVYGNI---LINKKKYNKQ----RVIPLEEVKLQSLEDDGQFRNGWLICTRGKSFAVYAATAKEKDDWMSHIQRCIDDLLSSSGKKPSDEHAAV----------------------WIPDSEAHSCMVCNKSHFTVLNRRHHCRQCGAVVCGSCSTNRFLIPSQSSKPIRVCDTCYGTLNIN 216          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000011191 (supercontig:LSalAtl2s:LSalAtl2s760:92787:95797:-1 gene:EMLSAG00000011191 transcript:EMLSAT00000011191 description:"maker-LSalAtl2s760-augustus-gene-1.14")

HSP 1 Score: 74.7146 bits (182), Expect = 4.980e-14
Identity = 30/64 (46.88%), Postives = 42/64 (65.62%), Query Frame = 0

Query:  581 PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPL-RYCQYRPQRVCDQCF 643
            PP W+PD++  +C  C +D   +FKRRHHCR CG V C+ CS    PL +Y   +P RVC++C+
Sbjct:  586 PPAWVPDEAAPICMGC-SDQFTIFKRRHHCRSCGLVFCYRCSGQSVPLPQYGIDKPVRVCNRCY 648          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000003844 (supercontig:LSalAtl2s:LSalAtl2s208:386765:391376:1 gene:EMLSAG00000003844 transcript:EMLSAT00000003844 description:"maker-LSalAtl2s208-augustus-gene-4.5")

HSP 1 Score: 71.633 bits (174), Expect = 4.846e-13
Identity = 50/188 (26.60%), Postives = 87/188 (46.28%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRGK--IADIFVKKGPFL-KLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDAT---RACLIVSEAADHSNE 415
            V  EL+ +E  YVN L  +   F+  + +  + +   +   E + IF+N+  I + +  +L DF   V NW+    I ++F+K    L K Y  ++  F         C    PRF   ++  +S+  CG+  ++  L++PVQRLP   L L   +  +  E  D+ D++   +A   +     H NE
Sbjct:  412 VFTELVQTESNYVNILKTIIEVFKKPLEDPDKIEGQFLNPTETKIIFSNLPPIYDLHSQMLADFTTIVSNWKDDVCIGNVFLKYADDLEKTYPPFVNFFETTKNCLLECGNAKPRFHAFLKVCQSKPECGRQTLTELLIRPVQRLPSISLLLNDLLKHTRKEK-DHPDSSALEKALNKIKAVMTHINE 598          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000003492 (supercontig:LSalAtl2s:LSalAtl2s190:411470:416644:-1 gene:EMLSAG00000003492 transcript:EMLSAT00000003492 description:"maker-LSalAtl2s190-augustus-gene-4.14")

HSP 1 Score: 67.3958 bits (163), Expect = 1.090e-11
Identity = 29/66 (43.94%), Postives = 36/66 (54.55%), Query Frame = 0

Query:  582 PVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILK 647
            P W+PD     C +C   F  L KRRHHCR CG+VLC+ C  +   L Y   +  RVC  C  IL+
Sbjct:  301 PWWVPDSDALTCMICDIKF-TLTKRRHHCRACGKVLCNHCCLDRFNLAYMDNKEARVCKPCKGILE 365          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000008338 (supercontig:LSalAtl2s:LSalAtl2s509:237196:263796:-1 gene:EMLSAG00000008338 transcript:EMLSAT00000008338 description:"maker-LSalAtl2s509-snap-gene-2.19")

HSP 1 Score: 65.855 bits (159), Expect = 3.580e-11
Identity = 62/258 (24.03%), Postives = 114/258 (44.19%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFV---KKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDN---FRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIY------LVLCTDLLIYARIS 477
            + Q L+ SE  YV++L  +  D++  + E     P I+   +   +F  + EIL+ +          + +W  + KI D+FV    K   L+ YS ++ NF +A    +   +R     + + + +   +  ++ +   L+KPVQR PQ+ L L+  + ++ P  VD +    A   +   A+  NE  R  +    F++ ++         L   DR L+KEG + +   N    I       L+L  D +I   +S
Sbjct:  109 IIQTLVSSENNYVSSLQRLVNDYKKPLEE---SSPLIISQSKITTLFYRISEILQIHYLFRIGLSQMILSWDSQEKIGDVFVASFSKAIVLETYSDFINNFNEAFNIVKYESKRKSALSDFL-DLKQLTSSDRISLFGLLVKPVQRFPQFILILQDLLKETPPGHVDRMALQLALTTLESLAEMLNERKREAEQFAAFKEKIKSIGGKTKGLLECKDRYLLKEGDLHQLEFNSSGQISRSKARRLLLINDYIICLSMS 362          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000008744 (supercontig:LSalAtl2s:LSalAtl2s543:167354:170453:1 gene:EMLSAG00000008744 transcript:EMLSAT00000008744 description:"maker-LSalAtl2s543-augustus-gene-1.78")

HSP 1 Score: 62.7734 bits (151), Expect = 3.185e-10
Identity = 27/68 (39.71%), Postives = 40/68 (58.82%), Query Frame = 0

Query:  581 PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQ-YRPQRVCDQCFQILK 647
            P +W+PD +  +C  C + F    +R+HHCR CG + C+ C+   +P+   Q Y P RVCD C+  LK
Sbjct:  768 PILWVPDHAGAVCMGCNSKFW-FGRRKHHCRSCGLLFCNNCTDQFSPIPTEQLYSPVRVCDDCYATLK 834          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213484|sp|Q6ZV73.2|FGD6_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 6; AltName: Full=Zinc finger FYVE domain-containing protein 24)

HSP 1 Score: 294.664 bits (753), Expect = 1.700e-83
Identity = 184/592 (31.08%), Postives = 308/592 (52.03%), Query Frame = 0

Query:  223 EEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEE-DPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMD-MHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCP-----PVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRL----------------YRGLFNGRKNSFVQLPNPSVLRKGRENGFE--VNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES--NADKWINALQDA 785
            E+  M      +A+E++ SE+ +V+ L L++ DFR  +     +    ++       I   + ++ E NRDLL + ++R+ +W  + +IADIFVKKGP+LK+YSTY++ F       +   ++ P F  +V+EFE    C  L +  YLLKPVQR+PQY+L L  Y+     ++ DY D   A  +V E A+H+N+ ++  DNF++L+++Q  ++  HE+VQ  R  +KEG + K +R  +      L  D L+Y   +P      +++   K+   + L+ + V+     E Y  +  I+S  RS  L A +  E+ EW+E+I +A+E+ ++++ +F  +       S D  D++ +    P     P+WIPD   TMC +C ++F  L  RRHHCR CG+++C ACSSN+  L Y + +P RVC+ CFQ L+   D   S R+                   + +GRK   +    P+ L++   N  +  ++G+L+        W+  WF +K K L+ + AS+D   + +  +LGF +I       ++K      + FQL H       + AE   +A KWI A Q+ 
Sbjct:  864 EDNGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLHWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYT--TP------VQSGMYKLNNMLSLAGMKVR-KPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPS------RSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEF-TLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQ-KLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKI----PAALKEVSANTEDSSMSGYLYRSKGNKKPWKHFWFVIKNKVLYTYAASEDVAALESQPLLGFTVI-------QVKDENSESKVFQLLHKNMLFYVFKAEDAHSAQKWIEAFQEG 1427          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213394|sp|Q69ZL1.2|FGD6_MOUSE (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 6)

HSP 1 Score: 282.722 bits (722), Expect = 1.497e-79
Identity = 179/591 (30.29%), Postives = 306/591 (51.78%), Query Frame = 0

Query:  223 EEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEE-DPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMD-MHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCP-----PVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILK-------------SNYDKDDSM--RLYRGLFNGRKNSFVQLPNPSVLRKGRENGFE--VNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES--NADKWINALQDA 785
            E+  M      +A+E++ SE+ +V+ L L++ DFR  +     +    ++       I   + ++ E NRDLL + ++R+  W  + +IADIFVKKGP+LK+YSTY++ F       +   ++ P F  +V+EFE    C  L +  YLLKPVQR+PQY+L L  Y+     +SVD+ D   A  +V E A+H+N+ ++  DNF++L+++Q  +   HE+VQ  R  +KEG + K +R  +      L  D L+Y   +P      +++   K+   + L+ + V+     E Y  +  I+S  RS  L A +  E+ +W+E+I  ++E+ ++++ +F  +       S D  D++ +    P     P+WIPD   TMC +C ++F  L  RRHHCR CG+++C ACSSN+  L Y + +  RVC+ CFQ L+              N+    S    +   + +GRK   +    P+ L++   N  +  ++G+L+    +   W+  WF +K K L+ + AS+D   + +  +LGF + L       +K      + FQL H G     + A+   +  +WI+A Q+ 
Sbjct:  834 EDAGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLTWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNVALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDALLYT--TP------MQSGMYKLNNMLSLAGMKVR-KPTQEAYQNELKIESVERSFILSASSAAERDDWLEAISSSIEEYAKKRITFCPS------RSLD-EDSERKEEVSPLGAKAPIWIPDTRATMCMICTSEF-TLTWRRHHCRACGKIVCQACSSNKYGLDYLKGQLARVCEHCFQELQKLDHQLSPRVGSPGNHKSPSSALSSVLHSIPSGRKQKKI----PAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTL-------VKDENSESKVFQLLHKGMVFYVFKADDAHSTQRWIDAFQEG 1396          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213610|sp|Q91ZT5.1|FGD4_MOUSE (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 4; AltName: Full=Actin filament-binding protein frabin; AltName: Full=FGD1-related F-actin-binding protein)

HSP 1 Score: 247.669 bits (631), Expect = 1.022e-69
Identity = 168/569 (29.53%), Postives = 295/569 (51.85%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFN-RDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPI-KKQNRN-GLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESNAD---KWINALQDAINIES 790
            +A ELL +ER YV+ L L++  F   + E  E +    P E    IF+N+  I  F+ + LL + + R++ W    +I DI  K  PFLK+Y  Y++ F +A +  +T  ER P+F+ + +E + ++ CG L +  ++L+P+QR+P+Y++ L+ Y+ K SP+S D+ DA ++  I+S AA HSN  IR  +N ++L+ +   +   E +V     LIKEG I K   RN    + YL L  ++L+Y      V   ++      V  ++ +  + + +  ++EEYP  F I    R+  L+A ++ +K EWI++++++++   QR  +F +A+   K +      +        P WI D+ VTMC  C   F+ L +RRHHCR CG V+C  CS  +A L Y   R  +VC  C+QI+    D ++  R  RG+        +++ +  V         EV   L +   +   W+K W  + ++    L+M+ A  D +  +T+ +LG+  ++D     ++  + +   +F+L  S +  +  FA  N +   KW+  +  A+  E+
Sbjct:  210 IATELLLTERAYVSRLDLLDQVFYCKLLE--EANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKTMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDSPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYC-----VPRFSLVGSKFTVRTRVGIDGMKI-VETHNEEYPHTFQISGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIA--KENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIISGFTDSEEKKR--RGI--------LEIESAEV-----SGNSEVCSFLQYMEKSK-PWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGY--VVD-----DMPKSADLPHSFKLTQSKS--VHSFAADNEELKQKWLKIILLAVTGET 743          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|116241363|sp|Q96M96.2|FGD4_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 4; AltName: Full=Actin filament-binding protein frabin; AltName: Full=FGD1-related F-actin-binding protein; AltName: Full=Zinc finger FYVE domain-containing protein 6)

HSP 1 Score: 244.588 bits (623), Expect = 1.515e-68
Identity = 167/576 (28.99%), Postives = 287/576 (49.83%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFN-RDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPIKK-QNRN-GLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDC-------PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFA---ESNADKWINALQDAINIES 790
            +A ELL +ER YVN L L++  F   + E  E +    P E    IF+N+  I  F+ + LL + + R++ W    +I DI  K  PFLK+Y  Y++ F +A +  +   ER P+F+ +V+E + ++ CG L +  ++L+PVQR+P+Y++ L+ Y+ K  P+S+D+ DA ++  I+S AA HSN  IR  +N ++L+ +   +   E +V     LIKEG I K   RN    + YL L  ++L+Y      V   ++      V  ++ +  + + +   +EEYP  F +    R+  L+A +  +K EWI+++++ ++   QR  +F +A+          +DND              P WI D+ VTMC  C   F+ L +RRHHCR CG V+C  CS  +A L Y   +  +VC  C+QI+    D ++  R  +G+                +     +G  V          +  W+K W  + ++    L+M+ A  D +  +T+ +LG+  ++D     E+  + +   +F+L  S +  +  FA   E    KW+  +  A+  E+
Sbjct:  210 IANELLLTERAYVNRLDLLDQVFYCKLLE--EANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYC-----VPKFSLVGSKFTVRTRVGIDGMKI-VETQNEEYPHTFQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIA---------KDNDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIISGFTDSEEKKR--KGILE--------------IESAEVSGNSVVCSFLQYMEKSKPWQKAWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGY--VVD-----EMPRSADLPHSFKLTQSKS--VHSFAADSEELKQKWLKVILLAVTGET 743          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213042|sp|O88387.1|FGD4_RAT (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 4; AltName: Full=Actin filament-binding protein frabin; AltName: Full=FGD1-related F-actin-binding protein)

HSP 1 Score: 242.276 bits (617), Expect = 9.963e-68
Identity = 153/511 (29.94%), Postives = 267/511 (52.25%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRD-LLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPI-KKQNRN-GLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGF 735
            +A ELL +ER YV+ L+L++  F   + E  E +    P E    IF+N+  I  F+   LL + + R++ W    +I DI  K  PFLK+Y  Y++ F +A +  +   ER P+F+ + +E + ++ CG L +  ++L+P+QR+P+Y++ L+ Y+ K SP++ D+ DA ++  I+S AA HSN  IR  +N ++L+ +   +   E +V     LIKEG I K   RN    + YL L  ++L+Y      V   ++      V  ++ +  + + +  ++EEYP  F +    R+  L+A ++ +K EWI++++++++   QR  +F +A+   K +      +        P WI D+ VTMC  C   F+ L +RRHHCR CG V+C  CS  +A L Y   R  +VC  C+QI+    + ++  R  RG+         ++ +  V         EV   L +   +   W+K W  + ++    L+M+ A  D +  +T+ +LG+
Sbjct:  210 IATELLLTERAYVSRLNLLDQVFYCKLLE--EANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKNMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDAPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYC-----VPRFSLVGSKFTVRTRVGIDGMKI-VETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIA--KENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIMSGFAESEEKKR--RGIL--------EIESAEV-----SGNSEVCSFLQYMEKSK-PWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGY 694          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213572|sp|Q7Z6J4.1|FGD2_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 2; AltName: Full=Zinc finger FYVE domain-containing protein 4)

HSP 1 Score: 236.113 bits (601), Expect = 2.443e-66
Identity = 159/572 (27.80%), Postives = 283/572 (49.48%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITE--KIEEDPNIMPLEEFEYIFTNMKEILEFNRDL-LHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMH-ELVQADRGLIKEGPIKKQN--RNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDC---PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKN----WFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDA 785
            + QELL++E+ YV  L L++   +VF  E  K        P +    IF+N+  I +F+    L + + R+++W    +I D+  K  PFLK+YS Y++NF  A++   T  ++ P F+E++   +S E  G L +  ++L+PVQR+P+Y+L L+ Y+ K   ++ D  DA +A  ++  AA HSN  I   +  + L  + +R+ +  ++V     L++EGP+ K +  RN   + YL L  ++L+Y    P VI    +    +V  +I ++ + V+   ++ E+P  F +    R+  L+A+++ E + W+++ + A++   +R  +F +A    +    D ++ + +  +     P W+ D  VTMC  C   F+ L +RRHHCR CG V+C  CS   A L+Y   RP RVC  C+  L  N   +      RG                +L KG     + +    F      KW K+    W  +       L+++ A  D +  +++ +LG+ + + P+          + R FQL+ SG    T+ AE+     +W+ A++ A
Sbjct:  106 IVQELLETEQAYVARLHLLD---QVFFQELLKTARSSKAFPEDVVRVIFSNISSIYQFHSQFFLPELQRRLDDWTANPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWTDKSPLFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQADAQKALDMIFSAAQHSNAAITEMERLQDLWEVYQRLGLEDDIVDPSNTLLREGPVLKISFRRNDPMERYLFLFNNMLLYC--VPRVIQVGAQ---FQVRTRIDVAGMKVRELMDA-EFPHSFLVSGKQRTLELQARSQEEMISWMQAFQAAIDQIEKRNETFKAAA---QGPEGDIQEQELQSEELGLRAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCARCSDYRAELKYDDNRPNRVCLHCYAFLTGNVLPEAKEDKRRG----------------ILEKGSSATPDQSLMCSFLQLIGDKWGKSGPRGWCVIPRDDPLVLYVYAAPQDMRAHTSIPLLGYQVTVGPQG---------DPRVFQLQQSGQL-YTFKAETEELKGRWVKAMERA 639          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213586|sp|Q8BY35.1|FGD2_MOUSE (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 2)

HSP 1 Score: 224.942 bits (572), Expect = 2.699e-62
Identity = 159/567 (28.04%), Postives = 284/567 (50.09%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEED--PNIMPLEEFEYIFTNMKEILEFNRDL-LHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMH-ELVQADRGLIKEGPIKKQNRNGLDDI--YLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDAIN 787
            V +ELL++E+ YV  L L++   +VF  E + E       P +  + IF+N+  I  F+    L + + RV++W    +I D+  K  PFLK+YS Y++NF  A++   T +++   F+E+V   +  E    L +  ++L+PVQR+P+Y+L L+ YV K   ++ D  DA RA  ++  AA HSN  I   +  + L  + +R+ +  ++V     L++EGP+ K +    D +  YLVL  ++L+Y    P V+    +    +V  +I ++ + V+   ++ E+P  F +    R+  L+A+++ E + W+++ + A++   +R  +F +AV   +  + + +          P W+ D  VTMC  C   F+ L +RRHHCR CG V+C  CS   A L+Y   RP RVC  C+  L  N          RG+     ++    P  S++     +  ++ G    +S       ++W  +       L+++ A  D K  +++ +LG+ +I  P+          + R FQL+ SG    T+ AES     +W+ A++ A +
Sbjct:  106 VVRELLETEQAYVARLHLLD---QVFFQELLREAGRSKAFPEDVVKLIFSNISSIYRFHAQFFLPELQRRVDDWAATPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWMDKSQPFQEVVTRIQCSEASSSLTLQHHMLEPVQRIPRYELLLKEYVQKLPAQAPDLEDAQRALDMIFSAAQHSNAAIAEMERLQGLWDVYQRLGLEDDIVDPSNTLLREGPVLKISFRRSDPMERYLVLFNNMLLYC--VPRVLQVGAQ---FQVRTRIDVAGMKVRELTDA-EFPHSFLVSGKQRTLELQARSRDEMVSWMQACQAAIDQVEKRSETFKAAVQGPQGDTQEPKPQVEELGLRAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCAKCSDYRAELKYDSNRPNRVCLTCYTFLTGNVLPQGKEDKRRGILEKEASA---APEQSLVC----SFLQLIGDKCSRSLP-----RSWCVIPRDDPLVLYVYAAPQDTKAHTSIPLLGYQVISGPQG---------DPRVFQLQQSGQQ-YTFKAESVELQGRWVTAIKRAAS 641          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|296439343|sp|Q6ZNL6.3|FGD5_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 5; AltName: Full=Zinc finger FYVE domain-containing protein 23)

HSP 1 Score: 217.624 bits (553), Expect = 1.307e-57
Identity = 171/597 (28.64%), Postives = 283/597 (47.40%), Query Frame = 0

Query:  224 EGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIE----EDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPD-ASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRM-DMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADN-SEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDN-DFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSN--------YDKDDSMR--LYRGLFNGRK-NSFVQLPNPSVLRKGRE------------NGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAE--SNADKWINALQDA 785
            EGQ SR A ++AQELL SE+ YV  L  +N DF   +   ++    E  + +  EE     + +  I + ++ +L + ++R+ NW    K+AD+F+ +      ++T++  F        E CL   PR    V+EFE     G       LL+ VQRL QY++ L  Y+N   P+S +Y +   A  ++S+  D +N+ +   +N ++LV ++  +    +L+Q  R  +KEG + K         +L L  D+L+Y         P  +    K   K  L+   ++++    E+ P    I++S     L A +  E+ EW   + +A+ ++ + QA     +  F  HS + R+       + PP  +P   V MC  C  DF  L  RRHHC  CG+++C  CS N+ PL+Y + R  +VCD CF  LK           ++  SM   L    F+G   +S  Q  NPS  +K ++             G  ++G+L         W+K WF +K K L+ + AS+D   + ++ +LGF +  + E G+      E G  F L H  T   ++ AE  ++A +WI A++DA
Sbjct:  888 EGQ-SR-ALVIAQELLSSEKAYVEMLQHLNLDFHGAVMRALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNWESQQKVADVFLAREQGFDHHATHILQFDRYLGLLSENCL-HSPRLAAAVREFEQSVQGGSQTAKHRLLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQGALSLISKVTDRANDSMEQGENLQKLVHIEHSVRGQGDLLQPGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLY-------TYPQKDG---KYRLKNTLAVANMKVSRPVMEKVPYALKIETSESCLMLSASSCAERDEWYGCLSRALPEDYKAQA-----LAAF-HHSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDF-SLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFSGSAFSSVFQSINPSTFKKQKKVPSALTEVAASGEGSAISGYLSRCKRGKRHWKKLWFVIKGKVLYTYMASEDKVALESMPLLGFTIAPEKEEGSS-----EVGPIFHLYHKKTLFYSFKAEDTNSAQRWIEAMEDA 1459          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|28202247|sp|P98174.2|FGD1_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 1; AltName: Full=Faciogenital dysplasia 1 protein; AltName: Full=Rho/Rac guanine nucleotide exchange factor FGD1; Short=Rho/Rac GEF; AltName: Full=Zinc finger FYVE domain-containing protein 3)

HSP 1 Score: 208.379 bits (529), Expect = 4.514e-55
Identity = 166/543 (30.57%), Postives = 263/543 (48.43%), Query Frame = 0

Query:  220 QPSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPN--IMPLEEFEYIFTNMKEILEFNRD-LLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPI-KKQNRNG-LDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDC-------PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAG 744
            Q S E  + +  F +A ELL +E+ YV+ L L++   +VF    +EE  N    P +    IF+N+  I  F++  LL + + R+E W    +I DI  K  PFLK+Y  Y++NF  A +   T  ER  +F+ ++ E +  E CG L +  ++L+PVQR+P+Y+L L+ Y+ K    S D  DA ++  +++ AA+HSN  IR  +   +L+++   +   E +V   + LIKEG I K   +NG   D YL+L  D L+Y      V    +      V  +I +  + ++ + N    P  F +    RS  L+A+T+ EK +W+++I   +  + Q   +F   ++N    ST+  D D   N          P  I +  VTMC  C   F+ + KRRHHC+ CG V+C  CS   A L Y   R  RVC  C+  L        +   +      R+ S ++           EN   +   LH+       W K WF + E     L+++ A  D K   +L ++GF+ +  PEAG
Sbjct:  363 QESVELTVQQKVFHIANELLQTEKAYVSRLHLLD---QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYC-----VPRLRLLGQKFSVRARIDVDGMELKESSNL-NLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFK--LLN----STNREDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLVYDNNRSNRVCTDCYVALHGVPGSSPACSQH---TPQRRRSILE----KQASVAAENSV-ICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFE-VGPPEAG 881          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|341940697|sp|P52734.2|FGD1_MOUSE (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 1; AltName: Full=Faciogenital dysplasia 1 protein homolog; AltName: Full=Rho/Rac guanine nucleotide exchange factor FGD1; Short=Rho/Rac GEF; AltName: Full=Zinc finger FYVE domain-containing protein 3)

HSP 1 Score: 207.994 bits (528), Expect = 6.283e-55
Identity = 164/544 (30.15%), Postives = 263/544 (48.35%), Query Frame = 0

Query:  220 QPSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPN--IMPLEEFEYIFTNMKEILEFNRD-LLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPI-KKQNRNG-LDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCP--------PVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAG 744
            Q S E  + +  F +A ELL +E+ YV+ L L++   +VF    +EE  N    P +    IF+N+  I  F++  LL + + R+E W    +I DI  K  PFLK+Y  Y++NF  A +   T  ER  +F+ ++ E +  E CG L +  ++L+PVQR+P+Y+L L+ Y+ K    S D  DA ++  +++ AA+HSN  IR  +   +L+++   +   E +V   + LIKEG I K   +NG   D YL+L  D L+Y      V    +      V  +I +  + ++ + N    P  F +    RS  L+A+T+ EK +W+++I   +  + Q        +  FK  ++  RD++    + P        P  I +  VTMC  C   F+ + KRRHHC+ CG V+C  CS   A L Y   R  RVC  C+  L        +   +      R+ S ++           EN   +   LH+       W K WF + E     L+++ A  D K   +L ++GF+ +  PEAG
Sbjct:  362 QESVELTVQQKVFHIANELLQTEKAYVSRLHLLD---QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYC-----VPRLRLLGQKFSVRARIDVDGMELKESSNL-NMPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQ-------TLETFKLLNSTNRDDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLIYDNNRSNRVCTDCYVALHGAPGSSPACSQH---TPQRRRSILE----KQASVAAENSV-ICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFE-VGPPEAG 880          

BLAST of and ph domain-containing vs. nr
Match: gi|985400415|ref|XP_015367879.1| (PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6-like isoform X2 [Diuraphis noxia])

HSP 1 Score: 341.273 bits (874), Expect = 1.420e-101
Identity = 198/577 (34.32%), Postives = 319/577 (55.29%), Query Frame = 0

Query:  222 SEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTV--QIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDKDDSMRLYRG--------LFNGRKNSFVQ------------LPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES 773
            +EE      +    +EL+ +E+ +++ L+L+   F  F+ E+   D  ++P  +   I + + ++L  N DLL D ++R++NW    KIAD+ VKKGPFLKLYSTY+QNF       +   ++YPRF++ V++FE+ + C KL I  Y+L P+QR+ +Y+L LE Y+      S+DY D   A  IV + A+H+NE ++H D   +L++LQ ++  + +++  R LIKEG + K +R  +   Y +L  D L+Y      V         LK+ Y++PLS + V   I DN      +F+I +  RS  LRAK+ +E  EW+  +EKA+ +++ +Q SF    +N K  S +      +     P+WI D  VTMCQ C T+F   F RRHHCR CG+V+C +CS N+APLRY +++  RVCD C+  +LK   DK   MR            + +  KNSF +            +P         ++G +++G L ++      W++ WF LK + L+M+KAS+D   ++T+ +LG+ +   PE  N     F++   FQL H+G  PL + +++
Sbjct:  233 TEEIPTKAKSLRTVEELISTEKIFIDVLNLLCKTFVTFV-EQTGVDVKLIPSTDLSKIISPLPQLLSLNEDLLQDMENRLKNWNENPKIADVIVKKGPFLKLYSTYIQNFESQCNLLDEYCQKYPRFQKCVKDFEASDVCKKLTIKHYMLTPIQRITKYRLLLENYLKNQDEGSIDYQDTIIALGIVCDVANHANESMKHGDCVSKLLQLQSQLGSYIIIKPGRELIKEGELYKLSRKDMQLRYFILLNDCLLYTSYYGTV-------SGLKINYELPLSGMKVFLPITDNCLN---EFSIITITRSFTLRAKSAVELKEWVNVLEKAIREHTNKQLSF----LNMKFVSKNVGCEPLQLGYEAPIWIQDCRVTMCQSCATEFTVTF-RRHHCRACGKVVCSSCSENKAPLRYMKFQSARVCDDCYDYLLKEFEDKILEMRQSSSNSDFEILKMVDTVKNSFKKSGVWSSKKLVKYVPQRLKEVMANDSGSQMSGWL-YRREKRKSWKRFWFVLKXQVLYMYKASEDVVALNTIPVLGYSVQTFPEGTN--YEEFDSSCVFQLAHAGQNPLIFCSDT 790          

BLAST of and ph domain-containing vs. nr
Match: gi|1339072375|ref|XP_023723414.1| (FYVE, RhoGEF and PH domain-containing protein 6-like isoform X2 [Cryptotermes secundus])

HSP 1 Score: 352.829 bits (904), Expect = 1.449e-101
Identity = 206/591 (34.86%), Postives = 331/591 (56.01%), Query Frame = 0

Query:  218 NYQPSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFR--VFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDK----DDSMRLYRGLFNGRKNSFVQLPNPSVLR------------KGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDA 785
            N+   EE +  + AF +AQEL+ SER +++ L L++ DFR  V      +  P ++P  E + I  ++ ++   N DLL D + R+ NW    KIAD+ V+KGPFLKLY++Y+QNF       + C ++Y RF ++V+EFE+   C KL +  Y+LKPVQR+PQY+L LE Y++  SP S D  D   A  IV + ADH+N  I+  D+  +L++LQ ++  +E+++  R  +K+G + K +R G+   Y +L  D L+Y      V     ++  LKV Y++PLS++ V I   +E+Y  +F+I S  RS  L A++  E+ EW+++++KA+ D + RQ SF +  V       +     F+     PVWI D  VTMCQ C  +F   F RRHHCR CG+V+C  CS   APL+Y +++  RVC++C   +LK   D     + +M+   G      ++F +L   S  R               + G +++G L  +S  +  W++ WF LKE+ L+++KAS+D   + ++ +LG+ +    E   +L    +    F+L H G  PL + A+S   A++WI A+ +A
Sbjct:  817 NHSQVEETRQDKKAFYIAQELMTSERAFIDVLKLLSVDFRQAVHAVAARQRYP-VIPDAELDKILNSLPQLRSLNEDLLRDLEIRINNWNSIKKIADVIVRKGPFLKLYTSYIQNFESQCIYLDECCQKYHRFAKVVKEFEASPRCQKLSLKHYMLKPVQRIPQYRLLLEDYLHHLSPFSPDLDDTRTALKIVCDVADHANRSIKLGDHLSKLLQLQSQLGNYEIIKPGRMFLKDGELSKLSRKGMQPRYFILLNDCLLYTSYYGSV-----QSSGLKVNYELPLSSMKVSIP-QAEDYRNEFSIISVKRSFTLSARSLNERQEWVDALQKAITDYNSRQLSFQNMKVT-SSAKNECSSEPFKLGQEAPVWIQDRRVTMCQSCTAEFTVTF-RRHHCRACGKVVCGDCSDFRAPLQYMRFQSARVCEECHNTLLKEARDPTSEVNQAMKHELGNTISIMDAFKRLGPVSGKRVKKYIPQRLKEVTANDTGSQMSGWLQRRSRRS--WKRLWFVLKEQVLYVYKASEDVVALESIPVLGYAVEPMKERHFQLYEGIDAKFVFKLAHPGQRPLIFHADSEHLANRWIAAMSEA 1396          

BLAST of and ph domain-containing vs. nr
Match: gi|939253067|ref|XP_014246193.1| (FYVE, RhoGEF and PH domain-containing protein 6-like isoform X1 [Cimex lectularius])

HSP 1 Score: 341.273 bits (874), Expect = 1.489e-101
Identity = 196/595 (32.94%), Postives = 321/595 (53.95%), Query Frame = 0

Query:  223 EEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFI-TEKIEEDPN-IMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGL--------------FNGRKNSFVQLPNPSVLRK----------GRENGFEVNGHLHFKSTTTGK--WRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES--NADKWINALQDA 785
            +E    + AF++A+E + SE+ Y+NAL L+ + F   + T  I  +   ++ L +   I T + ++   N +LL D + R++NW    KIAD+ VKKGPFLKLYSTY++NF       + C  +YP+F + + EFE+ E C KL +  Y+LKPVQR+PQY+L LE+Y+ +   +S +Y D   A  IV +   H+N  I+  DN  +L+++Q  +  +E+++  R  IKEG + K +R  +   Y VL +D L+Y   S  +         L+V Y++ LS + V      +    +F+I +S RS  LRA+T+ E  +W+ ++  A+++N+QRQ +F    ++ K           +     PVWI D   TMCQ+C  +F   F RRHHCRCCG+V+C  CS+N+APL+Y +++  RVC++C+  L   ++ D + +++  +                  K SF +       +K            + G +++G L+ K    GK  W++ WF LKEK L+++KAS D     ++ +LG+ +    E G+E     ++   F L H G   L + + S   A+ WI AL++A
Sbjct:  226 KENSKQKDAFMIAKEFMTSEKVYLNALHLIVFHFTEHLKTYAINNNCGAVISLTDLSKIITTLPQLQSLNENLLTDIELRIKNWSHLPKIADVIVKKGPFLKLYSTYIKNFESTCTFLDECCVKYPKFAKALNEFENSEICKKLTLKHYMLKPVQRVPQYRLLLEKYLEQIDEDSTEYADTKSALAIVEDVLHHANSSIKLGDNLSKLLQIQFSLGGYEIIKPGREFIKEGELYKLSRKEMQLRYFVLLSDCLLYTTYSSSI-------SGLRVKYELQLSGMKVY---KHQMDILEFSIITSTRSFTLRARTEEECADWLNALLSAIKENNQRQLTF----LSMKCMDKSITFETLKLGKEAPVWIQDKKTTMCQICTAEFTVTF-RRHHCRCCGKVVCGTCSNNKAPLQYLKFQSARVCEECYDYLLKEFE-DPANKIFENVKAELQLSDDETAVTLENLKASFKKFDCAKKTKKFIPQRLKEVTANDTGSQMSGWLYRK----GKRGWKRQWFVLKEKILYVYKASHDVVAYQSIPVLGYTIDQSSEVGSE---EIDSNLVFSLNHPGQSSLIFSSPSKQTAEMWITALKEA 797          

BLAST of and ph domain-containing vs. nr
Match: gi|1126201659|ref|XP_019634183.1| (PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6-like [Branchiostoma belcheri])

HSP 1 Score: 340.887 bits (873), Expect = 1.635e-101
Identity = 206/608 (33.88%), Postives = 318/608 (52.30%), Query Frame = 0

Query:  214 GKSSNYQPSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPN-IMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRM-DMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKI--PLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDD-------------------SMRLYRGLFNGRKNSFVQLPN------PSVLRKGRENGF--EVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFA---ESNADKWINALQDA 785
            G  ++  P+ +G     AF +A E++ SE  +V+ L L+N DFR  +    E     I+       I   + ++ +FN  LL DFKDRV NW    +IAD+ VKKGP+LKLY+TY+++F  ++ A +    R P+F   V+EF+    C  L +  Y+LKPVQR+PQYKL L+ Y+   + ES DY D   A  IVSE ADH+NE ++  DNF +L+R+Q  +   HE+V+  R L+KEG +KK +R  +      L +D L+Y     G             +YK+   L    +++    +++  + +I S  RS  L A +  E+ +W++++  A+ DN+ ++++F   V +      D  ++   G    PVWIPD  VTMC  C  DF   + RRHHCR CG+V+C  CS+N APL+Y  Y+  RVC++C++ L   +   D                     RL R     R  SF +         PSVL++   N    +++G+L  K+   G WRK WF LK+K L+ +KAS+D   + +L +LGF +    EA  +        + F+L H G  P  YF    ++ + KW+ A+ +A
Sbjct:  199 GSKADIPPALKGD---KAFYIAHEIMSSEEVFVDVLKLLNEDFRAVVAAAGEASGQAIIDEASMTQILLYLPQLQQFNESLLKDFKDRVANWEQDPRIADVIVKKGPYLKLYTTYIKDFEKSTSALDEACRRLPKFAATVKEFQMSPRCANLAVKHYMLKPVQRIPQYKLLLDDYLKHLTEESPDYKDTKVALSIVSEVADHANEGMKQGDNFEKLLRIQHSLIGQHEIVKPGRKLLKEGMLKKLSRKEMQPRMFFLMSDALLYCTPIQG------------GMYKLNNMLQLAGMKVMKPVQDFLNELSIISVQRSFTLSASSPEERDDWMQALTDAIRDNAAKRSTFDEFVRHVDAVPGDKSNSLVLGYKA-PVWIPDSRVTMCMGCTCDFTVTW-RRHHCRACGKVVCGTCSANRAPLQYLDYKAVRVCEECYETLSKEFQAHDDGSSAAGSPEKTSADKQRGGFRLSRATIQARFKSFKKTARKAKKSIPSVLKEVTANNVNSDMSGYLQRKTKREG-WRKLWFVLKDKVLYTYKASEDVAALESLPLLGFTVTTFTEAQEDTPP----DQIFKLAHQGR-PDVYFRTDDKAASKKWVAAMMNA 783          

BLAST of and ph domain-containing vs. nr
Match: gi|1339072371|ref|XP_023723411.1| (uncharacterized protein LOC111873163 isoform X1 [Cryptotermes secundus] >gi|1339072373|ref|XP_023723413.1| uncharacterized protein LOC111873163 isoform X1 [Cryptotermes secundus] >gi|1330879456|gb|PNF17187.1| hypothetical protein B7P43_G06588 [Cryptotermes secundus] >gi|1330879457|gb|PNF17188.1| hypothetical protein B7P43_G06588 [Cryptotermes secundus])

HSP 1 Score: 352.443 bits (903), Expect = 3.374e-101
Identity = 206/591 (34.86%), Postives = 331/591 (56.01%), Query Frame = 0

Query:  218 NYQPSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFR--VFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDK----DDSMRLYRGLFNGRKNSFVQLPNPSVLR------------KGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDA 785
            N+   EE +  + AF +AQEL+ SER +++ L L++ DFR  V      +  P ++P  E + I  ++ ++   N DLL D + R+ NW    KIAD+ V+KGPFLKLY++Y+QNF       + C ++Y RF ++V+EFE+   C KL +  Y+LKPVQR+PQY+L LE Y++  SP S D  D   A  IV + ADH+N  I+  D+  +L++LQ ++  +E+++  R  +K+G + K +R G+   Y +L  D L+Y      V     ++  LKV Y++PLS++ V I   +E+Y  +F+I S  RS  L A++  E+ EW+++++KA+ D + RQ SF +  V       +     F+     PVWI D  VTMCQ C  +F   F RRHHCR CG+V+C  CS   APL+Y +++  RVC++C   +LK   D     + +M+   G      ++F +L   S  R               + G +++G L  +S  +  W++ WF LKE+ L+++KAS+D   + ++ +LG+ +    E   +L    +    F+L H G  PL + A+S   A++WI A+ +A
Sbjct:  900 NHSQVEETRQDKKAFYIAQELMTSERAFIDVLKLLSVDFRQAVHAVAARQRYP-VIPDAELDKILNSLPQLRSLNEDLLRDLEIRINNWNSIKKIADVIVRKGPFLKLYTSYIQNFESQCIYLDECCQKYHRFAKVVKEFEASPRCQKLSLKHYMLKPVQRIPQYRLLLEDYLHHLSPFSPDLDDTRTALKIVCDVADHANRSIKLGDHLSKLLQLQSQLGNYEIIKPGRMFLKDGELSKLSRKGMQPRYFILLNDCLLYTSYYGSV-----QSSGLKVNYELPLSSMKVSIP-QAEDYRNEFSIISVKRSFTLSARSLNERQEWVDALQKAITDYNSRQLSFQNMKVT-SSAKNECSSEPFKLGQEAPVWIQDRRVTMCQSCTAEFTVTF-RRHHCRACGKVVCGDCSDFRAPLQYMRFQSARVCEECHNTLLKEARDPTSEVNQAMKHELGNTISIMDAFKRLGPVSGKRVKKYIPQRLKEVTANDTGSQMSGWLQRRSRRS--WKRLWFVLKEQVLYVYKASEDVVALESIPVLGYAVEPMKERHFQLYEGIDAKFVFKLAHPGQRPLIFHADSEHLANRWIAAMSEA 1479          

BLAST of and ph domain-containing vs. nr
Match: gi|985400413|ref|XP_015367878.1| (PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6-like isoform X1 [Diuraphis noxia])

HSP 1 Score: 341.658 bits (875), Expect = 3.401e-101
Identity = 198/577 (34.32%), Postives = 319/577 (55.29%), Query Frame = 0

Query:  222 SEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTV--QIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDKDDSMRLYRG--------LFNGRKNSFVQ------------LPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES 773
            +EE      +    +EL+ +E+ +++ L+L+   F  F+ E+   D  ++P  +   I + + ++L  N DLL D ++R++NW    KIAD+ VKKGPFLKLYSTY+QNF       +   ++YPRF++ V++FE+ + C KL I  Y+L P+QR+ +Y+L LE Y+      S+DY D   A  IV + A+H+NE ++H D   +L++LQ ++  + +++  R LIKEG + K +R  +   Y +L  D L+Y      V         LK+ Y++PLS + V   I DN      +F+I +  RS  LRAK+ +E  EW+  +EKA+ +++ +Q SF    +N K  S +      +     P+WI D  VTMCQ C T+F   F RRHHCR CG+V+C +CS N+APLRY +++  RVCD C+  +LK   DK   MR            + +  KNSF +            +P         ++G +++G L ++      W++ WF LK + L+M+KAS+D   ++T+ +LG+ +   PE  N     F++   FQL H+G  PL + +++
Sbjct:  282 TEEIPTKAKSLRTVEELISTEKIFIDVLNLLCKTFVTFV-EQTGVDVKLIPSTDLSKIISPLPQLLSLNEDLLQDMENRLKNWNENPKIADVIVKKGPFLKLYSTYIQNFESQCNLLDEYCQKYPRFQKCVKDFEASDVCKKLTIKHYMLTPIQRITKYRLLLENYLKNQDEGSIDYQDTIIALGIVCDVANHANESMKHGDCVSKLLQLQSQLGSYIIIKPGRELIKEGELYKLSRKDMQLRYFILLNDCLLYTSYYGTV-------SGLKINYELPLSGMKVFLPITDNCLN---EFSIITITRSFTLRAKSAVELKEWVNVLEKAIREHTNKQLSF----LNMKFVSKNVGCEPLQLGYEAPIWIQDCRVTMCQSCATEFTVTF-RRHHCRACGKVVCSSCSENKAPLRYMKFQSARVCDDCYDYLLKEFEDKILEMRQSSSNSDFEILKMVDTVKNSFKKSGVWSSKKLVKYVPQRLKEVMANDSGSQMSGWL-YRREKRKSWKRFWFVLKXQVLYMYKASEDVVALNTIPVLGYSVQTFPEGTN--YEEFDSSCVFQLAHAGQNPLIFCSDT 839          

BLAST of and ph domain-containing vs. nr
Match: gi|328700485|ref|XP_001945183.2| (PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6 [Acyrthosiphon pisum])

HSP 1 Score: 340.887 bits (873), Expect = 7.734e-101
Identity = 204/595 (34.29%), Postives = 330/595 (55.46%), Query Frame = 0

Query:  222 SEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTV--QIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDKDDSMRLYRG--------LFNGRKNSFVQ------------LPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDAINIE 789
            +EE      +    +EL+ +E+ +++ L+L+   F +F+ E+   D  ++P  +   I + + ++L  N DLL D ++R++NW    KIAD+ VKKGPFLKLYSTY+QNF   S   +   ++YPRF++ V++FE+ + C KL I  Y+L P+QR+ +Y+L LE Y+      S+DY D   A  IV + A+H+NE ++  D   +L++LQ  +  + +++  R LIKEG + K +R  +   Y +L  D L+Y      V         LK+ Y++PLS + V   I DN      +F+I +  RS  LRAK+ +E  EW+  +EKA+ +++ +Q SF    +N K  S +      +     P+WI D  VTMCQ C ++F   F RRHHCR CG+V+C +CS N+APLRY +++  RVCD C+  +LK   DK   MR            + +  KNSF +            +P         ++G +++G L ++      W++ WF LKE+ L+M+KAS+D   ++T+ +LG+ +   PE  N     F++   FQL H+G  PL + +++   A +WIN L +A  ++
Sbjct:  287 TEEIPTKAKSLRTVEELISTEKVFIDVLNLLCKTFVMFV-EQTGGDVKLIPSTDLSKIISPLPQLLSLNEDLLQDMENRMKNWNEHPKIADVIVKKGPFLKLYSTYIQNFESQSNLLDEYCQKYPRFQKCVKDFEASDVCKKLTIKHYMLTPIQRITKYRLLLESYLKNQDEGSIDYQDTIVALGIVCDVANHANESMKQGDCVSKLLQLQSLLGSYIIIKPGRELIKEGELYKLSRKDMQLRYFILLNDCLLYTSYYGTVAG-------LKINYELPLSGMKVFLPITDNCLN---EFSIITITRSFTLRAKSAVELKEWVNILEKAIREHTNKQLSF----LNMKFVSKNIGREPLQLGYEAPIWIQDCRVTMCQSCASEFTVTF-RRHHCRACGKVVCSSCSENKAPLRYMKFQSARVCDDCYDYLLKEFEDKILEMRQSSSNSDLEILKMVDTVKNSFKKSGVWSSKKLVKYVPQRLKEVMANDSGSQMSGWL-YRREKRKSWKRFWFVLKEQVLYMYKASEDVVALNTIPVLGYSVQTFPEGTN--YEEFDSSCVFQLAHAGQNPLIFCSDTEQLAKRWINTLNEATKLK 862          

BLAST of and ph domain-containing vs. nr
Match: gi|1192745269|ref|XP_021002874.1| (uncharacterized protein LOC107449669 [Parasteatoda tepidariorum])

HSP 1 Score: 350.903 bits (899), Expect = 9.019e-100
Identity = 205/592 (34.63%), Postives = 338/592 (57.09%), Query Frame = 0

Query:  229 RSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDP-NIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWR--GKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMH-ELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDN--DFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQIL--------KSNYDKDDSMRL---------YRGLFNGRKNSFVQLPNPSVLRK--GRENGFEVNGHLHFKSTTTGK-WRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFEN---GRAFQLEHSGTGPLTYFAES--NADKWINALQDAINIE 789
            +  F +AQE++ SE  +V+ L L+N DF+  I    ++   N++P +    I  ++ ++   N +LL + KDR+ENW   GKIAD+ VK GPFLKLYS Y+Q+F       E   ++YP F + V++FE+   C +L ++ ++LKP+QR+PQY+L L+ Y++    E VDY D   A  IVSE A H+N+ ++H DN ++L+ +Q  +  H E+++  R  IKEG + K +R G+   + VL  DLL+Y  ++P      ++    +V +++PL+ + V I    ++Y  +F+I S  RS  L A++  E+ EWI ++ KA+E+N+ ++++F++  +  K       D+  +F      PVWIPD  VTMCQ+C ++F   F RRHHCR CG+V+C  CSSN   L Y   R  RVCD C   L        +S     D+ ++         ++ +  G++N       PSVL++    + G  ++G+L  K    GK W++ WF +K+K L+ +KAS+D   + +L +LG+ +    E+ +E    FEN      FQL H G  P+ + A++  + ++WI+AL++A  +E
Sbjct: 2092 KKIFYIAQEIMTSEEVFVDTLKLLNVDFKAAIEAANQQKGMNVVPDDALSQILNHLPQLQHLNENLLMELKDRIENWDKIGKIADVIVKMGPFLKLYSWYIQDFEYNVSLLEESKKKYPLFAQAVKDFEASARCKRLALNHFMLKPIQRIPQYRLLLQEYLHHLPEEHVDYQDTVAALQIVSEVATHANDSMKHGDNAQKLISIQNSIMGHKEIIKPGRLFIKEGELMKLSRKGMQPRWFVLFNDLLLY--LTP------VQQGLYRVNHELPLTGMKVAIPIQ-QDYQNEFSIISVARSFTLAARSPEERQEWIIALTKAIEENASKRSTFTNTRLQQKTQDKAAEDDEAEFVLGRKAPVWIPDSRVTMCQLCTSEFTVTF-RRHHCRACGKVICSICSSNRISLPYLGNRIARVCDDCHVKLGPGSGTCTESAETDSDNQQIAVKSHLRTEHKHVKKGKRNL------PSVLKEVCANDQGSTISGYLQKK---VGKSWKREWFVIKDKVLYEYKASEDVAALKSLPLLGYQI----ESFSE-NIAFENIDPSVLFQLTHPGQAPIIFHADTVGSTERWISALKEASVLE 2659          

BLAST of and ph domain-containing vs. nr
Match: gi|1061482535|gb|ODM99815.1| (FYVE, RhoGEF and PH domain-containing protein 6 [Orchesella cincta])

HSP 1 Score: 334.339 bits (856), Expect = 1.212e-99
Identity = 198/599 (33.06%), Postives = 325/599 (54.26%), Query Frame = 0

Query:  214 GKSSNYQP--SEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDF-RVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELV-QADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDC--PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSM--------------RLYRGLFN-GRKNSFVQLPNPSVLR-KGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES--NADKWINALQDAI 786
            G  S Y+   +E     + +F VA+E+L SER +V+ L+L+  +F +            ++  ++ E I   +  + + N +LL D ++R+ +WR   KIADI VK GPFLK+Y+ Y+++F   S   +TC +R P F E +++FE  E C KL +  Y+LKPVQR+PQY+L LE Y+     ES DY D  +   IV + A+H+NE IR   N  +L+ LQ R+    ++ ++DR LIKEG ++K  R  L   +  L  D L     +    +P      LK+ Y++PL+ + V ++ N E+Y  +F++ S  RS  L AK+  E+ EW++++  A+ DN ++++  +           D+      G +    PVWI D  VTMCQ+C  +F   F RRHHCR CG+V+C  CS N+APL+Y Q    RVCD C++ L   +DK   +              R  +   N  ++ + ++   PS L      +G  ++G+L +++     W++ WF L ++ L+++ AS+D   + ++ ILG+ + +D     E + T EN   F+L H G  P+ + A+S   A++WI A+ +A+
Sbjct:  141 GSVSGYEDILAELSPKEKKSFYVAREILTSERTFVDVLNLLTVEFPKCLKAAAKYHGVPVVSDKDLEIILGGLPTLKQVNENLLVDLEERITHWREFPKIADILVKTGPFLKMYADYIKDFRKNSLHLDTCCQRSPLFGETIRDFELGERCHKLGLKHYMLKPVQRMPQYRLLLEDYLKSLEKESEDYNDTVKGIAIVKDVAEHANEAIRLQVNAEKLLHLQSRLTTGTIILKSDRQLIKEGELQKVCRKVLQPRFFALMNDCLFCFNYNAPAGSPK----DLKLRYELPLAGMRVSLSSN-EDYQFEFSVISVARSFNLVAKSSKEREEWMKALNDAIHDNIKKRSCCTP----------DYEIGFSLGKEVQLAPVWIQDQRVTMCQLCTAEFTVTF-RRHHCRACGKVVCGNCSGNQAPLQYLQNAAARVCDSCYECLLDEFDKLSGLSYNETDKNRASVRDRFKKVTLNVSKRATKIKRAVPSRLEVHANSSGSRISGYLQWRAREKKSWKRRWFVLIDRVLYIYAASEDIVAIKSIPILGWHVEMD--KSEEHQETEENQAVFRLTHMGQHPILFQADSIATAERWIAAMSEAV 721          

BLAST of and ph domain-containing vs. nr
Match: gi|1316158412|ref|XP_023224340.1| (titin-like isoform X3 [Centruroides sculpturatus])

HSP 1 Score: 347.821 bits (891), Expect = 9.658e-99
Identity = 197/583 (33.79%), Postives = 324/583 (55.57%), Query Frame = 0

Query:  229 RSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTN-MKEILEFNRDLLHDFKDRVENWR--GKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRR-MDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNY------------------------DKDDSMRL--YRGLFNGRKNSF---VQLPNPSVLRK--GRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRA---FQLEHSGTGPLTYFAES 773
            + AF +A+E++ SE  +++ L L+N D+R  I +  EE    +  EE    F     ++   N++LL+D KDR+E+W   GKIAD+ VK GPFLKLYS+Y+++F     A++    +YP F ++ +EFE    C KL +  Y+LKP+QR+PQY+L L+ Y+   + +S DY D   A  IVSE A+H+NE ++  DNF++LV +Q   +  +E+V+  R  +KEG + K +R  +   + +L  D L Y           ++    KV Y++PL+ + V I  + ++Y  +F+I S  RS  L A++  E+ EW++++ KA+E+N+ ++++F++A+   ++   +  DN F      PVWIPD  VTMCQ+C  +F   F RRHHCR CG+V+C  CS N+APL+Y  ++  +VCD+CFQ+L+  Y                        D D S      +  F G   +    ++   PSVL++    + G  ++G+L  +      W+  WF LK+K L+ +KA +D   + ++ +LGF +            ++EN  A   FQL H+G  P+ ++ +S
Sbjct: 1543 KKAFFIAREIMTSEEVFLSCLKLLNEDYRACIKKANEERGGTIISEEMINCFLGYFPQLQTLNQNLLNDLKDRIEHWEETGKIADVIVKIGPFLKLYSSYIRDFDSLEAAFDDARRKYPLFDQITKEFEMSSHCKKLALKHYMLKPIQRIPQYRLLLQEYLQNLTEDSPDYADTVNALQIVSEVANHANETLKLGDNFQKLVSIQNSILGSYEIVRPGRIFLKEGELMKLSRKEMQPRWFILFNDSLFYLIC--------MQQGLYKVNYELPLTGMKVSIPQH-QDYKNEFSIISVTRSFTLAARSLEERQEWVDALNKAIEENASKRSTFTTAM--LQKDKGEKSDNAFVLGKQAPVWIPDARVTMCQLCTREFTVTF-RRHHCRACGKVVCSLCSGNKAPLQYRNFQVAKVCDECFQVLQKEYEAVEPTEKTSEVGESGTSSELGETDSDSSHAFASIKAQFKGNVKAAGKKIKRHLPSVLKEVCANDQGSTISGYLRKRERRN--WKPYWFVLKDKVLYRYKACEDVAALESIPLLGFQV-------ETFTQSYENIEAELLFQLTHAGQLPIIFYTDS 2104