BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000008308 (supercontig:LSalAtl2s:LSalAtl2s503:255428:288085:-1 gene:EMLSAG00000008308 transcript:EMLSAT00000008308 description:"maker-LSalAtl2s503-augustus-gene-2.25")

HSP 1 Score: 61.2326 bits (147), Expect = 9.042e-10
Identity = 27/70 (38.57%), Postives = 38/70 (54.29%), Query Frame = 0

Query:  583 VWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDK 652
             W  D+ V  C  C  +F+  F+R+HHCR CG++ C  CS N+  L     +P RVCD C  +L   + K
Sbjct:  730 TWQKDNEVKECGSCTIEFNS-FRRKHHCRNCGKIFCDKCSDNKINLT-SSVKPSRVCDICHVVLFEAFTK 797          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000002300 (supercontig:LSalAtl2s:LSalAtl2s1434:49169:52872:1 gene:EMLSAG00000002300 transcript:EMLSAT00000002300 description:"maker-LSalAtl2s1434-augustus-gene-0.38")

HSP 1 Score: 60.4622 bits (145), Expect = 1.528e-9
Identity = 26/63 (41.27%), Postives = 34/63 (53.97%), Query Frame = 0

Query:  584 WIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQIL 646
            W  D  VT C  C + F  +  R+HHCR CG++ C  CSS  +       + QRVCD CF+ L
Sbjct:  725 WADDSEVTECVGCKSQFS-ITIRKHHCRNCGQIFCKDCSSKTSSNMKNYKKAQRVCDGCFEEL 786          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000007028 (supercontig:LSalAtl2s:LSalAtl2s39:241587:257015:-1 gene:EMLSAG00000007028 transcript:EMLSAT00000007028 description:"maker-LSalAtl2s39-snap-gene-2.10")

HSP 1 Score: 59.6918 bits (143), Expect = 2.497e-9
Identity = 63/237 (26.58%), Postives = 101/237 (42.62%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALS-LVNYDFRVFITEKIEEDPN-IMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVE-----------NWRGK--IADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGK-----LHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSE-----AADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGL 445
            V   +LDSE  Y+  LS L+ Y   + +T      PN ++P E+F+ IF  + E+ + +    +  K RVE           N  G   I   F       K+Y+++L N+P A +A     E YP+F +L +  + R   G      + +   L KPV  + ++ L L+  +  S  ES D      A   V          H+ E+  H +  RQ   L +   + EL + +R L
Sbjct:  368 VLNSVLDSESVYLEGLSVLLQYMKAMKVTLNT---PNPVIPKEDFDVIFYKIPELHDLHFTFYNSLKKRVESLIANESTSTVNMTGSNSIGHSFKMLACRTKIYASFLNNYPKALEALHRSTESYPQFADLTRSIKLRSVKGLQRGQCMSLEDLLHKPVAXVQKHCLCLQDLIKYSPSESPDLPSLNDALETVQNFLNEYNVSHAGELFPHQE--RQQRHLVKNSFIVELFEGNRKL 599          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000009074 (supercontig:LSalAtl2s:LSalAtl2s56:477026:514584:1 gene:EMLSAG00000009074 transcript:EMLSAT00000009074 description:"maker-LSalAtl2s56-snap-gene-5.8")

HSP 1 Score: 59.6918 bits (143), Expect = 2.531e-9
Identity = 53/159 (33.33%), Postives = 75/159 (47.17%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRGKIADIFVKKGPFLK-LYSTYLQNFPDASKAY-ETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSS 390
            +  ELL +E RYV+ L  V  ++R         D  ++   +   IF N+ EI +F+ ++L+   +R       IA  F      LK LY  Y QN P A +A  E   E  P      Q     E   +L +SSYLLKP+QRL +Y+L L   V  S+
Sbjct:  345 IISELLSTESRYVSDLESVLLNYR---------DKLVIANNKANIIFGNLDEIHDFHSNILYPDLERCGVXPAAIARTFSACCQDLKTLYCAYCQNMPSARQAVAELGGEATPSILYQCQT----EAGHQLPLSSYLLKPMQRLTKYQLMLRDLVESSN 490          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000012725 (supercontig:LSalAtl2s:LSalAtl2s966:23692:35478:1 gene:EMLSAG00000012725 transcript:EMLSAT00000012725 description:"maker-LSalAtl2s966-augustus-gene-0.23")

HSP 1 Score: 59.6918 bits (143), Expect = 3.154e-9
Identity = 27/62 (43.55%), Postives = 35/62 (56.45%), Query Frame = 0

Query:  584 WIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPL-RYCQYRPQRVCDQCFQ 644
            W  D+ V  C  C   F  +++RRHHCR CG+V C +CS  +A + R     P RVC QC Q
Sbjct: 2877 WWKDEGVESCVDCGVKF-TIYERRHHCRNCGKVFCSSCSQYQAEIPRLKIMHPVRVCKQCHQ 2937          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000012428 (supercontig:LSalAtl2s:LSalAtl2s90:953772:1016136:1 gene:EMLSAG00000012428 transcript:EMLSAT00000012428 description:"maker-LSalAtl2s90-snap-gene-9.17")

HSP 1 Score: 58.9214 bits (141), Expect = 5.594e-9
Identity = 56/230 (24.35%), Postives = 101/230 (43.91%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVE---------------NWRGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIR--------HDDNFRQLVRL--QRRMDMHEL 438
            V  EL+D+E  YV  L    Y  + ++ E ++ +   +   E   +F N++EI  F +  L   ++ +E               N    I   F+      KLYS++  +   A KA       + + ++ +     R+      + SYL+KP+QR+ +Y L L++  N + PES +      A + + + A+H NEM R         D  FRQ  +   Q+ +++H +
Sbjct: 1205 VILELVDTEHAYVRHLG---YLMKTYL-EPLKREA-FLSNSEISTLFGNIQEIYNFQQQFLRTLEEALESEAQFHSLDSTSQFKNVLFSIGSAFLYYVNHFKLYSSFCASHSKAQKALHPNDGNH-QLQDFLLSLNPRQQHSTA-LESYLIKPIQRILKYPLLLQQLKNLTRPESDEQQHLIEALIGMEKVAEHINEMQRIHEEYGAIFDHLFRQHQKTSKQKGLELHAM 1427          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000000286 (supercontig:LSalAtl2s:LSalAtl2s1042:61011:70383:1 gene:EMLSAG00000000286 transcript:EMLSAT00000000286 description:"maker-LSalAtl2s1042-snap-gene-0.39")

HSP 1 Score: 57.7658 bits (138), Expect = 1.224e-8
Identity = 50/214 (23.36%), Postives = 101/214 (47.20%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWR---GKIADIFVK--KGP----FLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHEL 438
            V  E   +ER +V  L +++   R+F   ++ ++P++M  +  + +F N+ ++++ +       KDR+++     G I+D+F++   GP     ++L S + QN     +  +    R  +F   + + E R  C +L + S L    QRL +Y L LE+ ++K +PE   Y              D  ++ +    N ++L  +Q+ +D   L
Sbjct:  463 VINEFFHTERSHVRNLKVLD---RIFY-RRMLDNPSLMSEDMVQKLFPNLDKLIQIHTKFNQIMKDRIKSQGFPIGDISDLFLEMFDGPNGDSLIELGSEFTQNQKFTIEELKKKRARDHKFDAFLSDLERRPECRRLGLESILPVEHQRLVKYPLLLEQ-LSKQTPEDSSYSTIKNCVERTKFILDSIDKRVAEAQNLQRLAEIQKNLDTSGL 671          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000005792 (supercontig:LSalAtl2s:LSalAtl2s311:368488:399678:1 gene:EMLSAG00000005792 transcript:EMLSAT00000005792 description:"maker-LSalAtl2s311-augustus-gene-3.14")

HSP 1 Score: 54.6842 bits (130), Expect = 9.395e-8
Identity = 42/215 (19.53%), Postives = 95/215 (44.19%), Query Frame = 0

Query:  221 PSEEGQMSRSAFLVAQELLDSERRYVNALS-LVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRGKI-ADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRM 433
            P  E    R+  +    ++++E  YV  +  L+   +R F      ++P     ++   IF N + +L  ++  L     R+E+W   +  D+F    P L +Y  Y++N     +    C ++ P F +L+   E +  C    +  +L  P+ ++P+Y + L   +  + P+ V+      A   + + +   ++ +   +N R+ + ++R +
Sbjct:  115 PHAESMRKRNCLVF--RMVEAEEEYVEQMEILITCFYRPFKMAASSKNPPCTH-DDINSIFLNSETVLFLHQIFLKGLTARMESWPTLVLGDLFDMLLPMLSIYQEYVRNHHYCLQVLTEC-KQSPSFAQLLNRLEKKPACKGRSLEIFLTYPMHQIPRYIITLHDLLAHTPPDHVEKKSLEHARDQLEDLSRQMHDEVSETENIRKNLAIERMI 325          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000011886 (supercontig:LSalAtl2s:LSalAtl2s837:147874:169845:-1 gene:EMLSAG00000011886 transcript:EMLSAT00000011886 description:"maker-LSalAtl2s837-snap-gene-0.18")

HSP 1 Score: 54.299 bits (129), Expect = 1.431e-7
Identity = 24/74 (32.43%), Postives = 38/74 (51.35%), Query Frame = 0

Query:  574 DFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQ-RVCDQCFQIL 646
            D+R ++    W+PD     C  C   F+  F+R+HHCR CG++ C +CSS     +   +  + RVC  C+   
Sbjct:   30 DYRNSELRQYWMPDAYSLECYDCNLRFNT-FRRKHHCRVCGQIFCSSCSSEYIDGKSLGFNGKLRVCKFCYDFF 102          

BLAST of and ph domain-containing vs. L. salmonis genes
Match: EMLSAG00000005595 (supercontig:LSalAtl2s:LSalAtl2s2:284284:287354:-1 gene:EMLSAG00000005595 transcript:EMLSAT00000005595 description:"maker-LSalAtl2s2-augustus-gene-2.30")

HSP 1 Score: 53.5286 bits (127), Expect = 1.620e-7
Identity = 25/66 (37.88%), Postives = 35/66 (53.03%), Query Frame = 0

Query:  579 DCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPL-RYCQYRPQRVCDQCF 643
            D  P W+     T+C  C  +F  +  R+HHCR CG+V C  CSS    L ++   +  RVC+ CF
Sbjct:  159 DTAPAWVEG---TVCHRCRVEF-GVMTRQHHCRACGQVFCSKCSSKSCNLPKFGIEKEVRVCESCF 220          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213484|sp|Q6ZV73.2|FGD6_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 6; AltName: Full=Zinc finger FYVE domain-containing protein 24)

HSP 1 Score: 294.664 bits (753), Expect = 1.700e-83
Identity = 184/592 (31.08%), Postives = 308/592 (52.03%), Query Frame = 0

Query:  223 EEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEE-DPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMD-MHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCP-----PVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRL----------------YRGLFNGRKNSFVQLPNPSVLRKGRENGFE--VNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES--NADKWINALQDA 785
            E+  M      +A+E++ SE+ +V+ L L++ DFR  +     +    ++       I   + ++ E NRDLL + ++R+ +W  + +IADIFVKKGP+LK+YSTY++ F       +   ++ P F  +V+EFE    C  L +  YLLKPVQR+PQY+L L  Y+     ++ DY D   A  +V E A+H+N+ ++  DNF++L+++Q  ++  HE+VQ  R  +KEG + K +R  +      L  D L+Y   +P      +++   K+   + L+ + V+     E Y  +  I+S  RS  L A +  E+ EW+E+I +A+E+ ++++ +F  +       S D  D++ +    P     P+WIPD   TMC +C ++F  L  RRHHCR CG+++C ACSSN+  L Y + +P RVC+ CFQ L+   D   S R+                   + +GRK   +    P+ L++   N  +  ++G+L+        W+  WF +K K L+ + AS+D   + +  +LGF +I       ++K      + FQL H       + AE   +A KWI A Q+ 
Sbjct:  864 EDNGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLHWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYT--TP------VQSGMYKLNNMLSLAGMKVR-KPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPS------RSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEF-TLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQ-KLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKI----PAALKEVSANTEDSSMSGYLYRSKGNKKPWKHFWFVIKNKVLYTYAASEDVAALESQPLLGFTVI-------QVKDENSESKVFQLLHKNMLFYVFKAEDAHSAQKWIEAFQEG 1427          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213394|sp|Q69ZL1.2|FGD6_MOUSE (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 6)

HSP 1 Score: 282.722 bits (722), Expect = 1.497e-79
Identity = 179/591 (30.29%), Postives = 306/591 (51.78%), Query Frame = 0

Query:  223 EEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEE-DPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMD-MHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCP-----PVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILK-------------SNYDKDDSM--RLYRGLFNGRKNSFVQLPNPSVLRKGRENGFE--VNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES--NADKWINALQDA 785
            E+  M      +A+E++ SE+ +V+ L L++ DFR  +     +    ++       I   + ++ E NRDLL + ++R+  W  + +IADIFVKKGP+LK+YSTY++ F       +   ++ P F  +V+EFE    C  L +  YLLKPVQR+PQY+L L  Y+     +SVD+ D   A  +V E A+H+N+ ++  DNF++L+++Q  +   HE+VQ  R  +KEG + K +R  +      L  D L+Y   +P      +++   K+   + L+ + V+     E Y  +  I+S  RS  L A +  E+ +W+E+I  ++E+ ++++ +F  +       S D  D++ +    P     P+WIPD   TMC +C ++F  L  RRHHCR CG+++C ACSSN+  L Y + +  RVC+ CFQ L+              N+    S    +   + +GRK   +    P+ L++   N  +  ++G+L+    +   W+  WF +K K L+ + AS+D   + +  +LGF + L       +K      + FQL H G     + A+   +  +WI+A Q+ 
Sbjct:  834 EDAGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLTWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNVALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDALLYT--TP------MQSGMYKLNNMLSLAGMKVR-KPTQEAYQNELKIESVERSFILSASSAAERDDWLEAISSSIEEYAKKRITFCPS------RSLD-EDSERKEEVSPLGAKAPIWIPDTRATMCMICTSEF-TLTWRRHHCRACGKIVCQACSSNKYGLDYLKGQLARVCEHCFQELQKLDHQLSPRVGSPGNHKSPSSALSSVLHSIPSGRKQKKI----PAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTL-------VKDENSESKVFQLLHKGMVFYVFKADDAHSTQRWIDAFQEG 1396          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213610|sp|Q91ZT5.1|FGD4_MOUSE (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 4; AltName: Full=Actin filament-binding protein frabin; AltName: Full=FGD1-related F-actin-binding protein)

HSP 1 Score: 247.669 bits (631), Expect = 1.022e-69
Identity = 168/569 (29.53%), Postives = 295/569 (51.85%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFN-RDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPI-KKQNRN-GLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESNAD---KWINALQDAINIES 790
            +A ELL +ER YV+ L L++  F   + E  E +    P E    IF+N+  I  F+ + LL + + R++ W    +I DI  K  PFLK+Y  Y++ F +A +  +T  ER P+F+ + +E + ++ CG L +  ++L+P+QR+P+Y++ L+ Y+ K SP+S D+ DA ++  I+S AA HSN  IR  +N ++L+ +   +   E +V     LIKEG I K   RN    + YL L  ++L+Y      V   ++      V  ++ +  + + +  ++EEYP  F I    R+  L+A ++ +K EWI++++++++   QR  +F +A+   K +      +        P WI D+ VTMC  C   F+ L +RRHHCR CG V+C  CS  +A L Y   R  +VC  C+QI+    D ++  R  RG+        +++ +  V         EV   L +   +   W+K W  + ++    L+M+ A  D +  +T+ +LG+  ++D     ++  + +   +F+L  S +  +  FA  N +   KW+  +  A+  E+
Sbjct:  210 IATELLLTERAYVSRLDLLDQVFYCKLLE--EANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKTMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDSPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYC-----VPRFSLVGSKFTVRTRVGIDGMKI-VETHNEEYPHTFQISGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIA--KENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIISGFTDSEEKKR--RGI--------LEIESAEV-----SGNSEVCSFLQYMEKSK-PWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGY--VVD-----DMPKSADLPHSFKLTQSKS--VHSFAADNEELKQKWLKIILLAVTGET 743          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|116241363|sp|Q96M96.2|FGD4_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 4; AltName: Full=Actin filament-binding protein frabin; AltName: Full=FGD1-related F-actin-binding protein; AltName: Full=Zinc finger FYVE domain-containing protein 6)

HSP 1 Score: 244.588 bits (623), Expect = 1.515e-68
Identity = 167/576 (28.99%), Postives = 287/576 (49.83%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFN-RDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPIKK-QNRN-GLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDC-------PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFA---ESNADKWINALQDAINIES 790
            +A ELL +ER YVN L L++  F   + E  E +    P E    IF+N+  I  F+ + LL + + R++ W    +I DI  K  PFLK+Y  Y++ F +A +  +   ER P+F+ +V+E + ++ CG L +  ++L+PVQR+P+Y++ L+ Y+ K  P+S+D+ DA ++  I+S AA HSN  IR  +N ++L+ +   +   E +V     LIKEG I K   RN    + YL L  ++L+Y      V   ++      V  ++ +  + + +   +EEYP  F +    R+  L+A +  +K EWI+++++ ++   QR  +F +A+          +DND              P WI D+ VTMC  C   F+ L +RRHHCR CG V+C  CS  +A L Y   +  +VC  C+QI+    D ++  R  +G+                +     +G  V          +  W+K W  + ++    L+M+ A  D +  +T+ +LG+  ++D     E+  + +   +F+L  S +  +  FA   E    KW+  +  A+  E+
Sbjct:  210 IANELLLTERAYVNRLDLLDQVFYCKLLE--EANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYC-----VPKFSLVGSKFTVRTRVGIDGMKI-VETQNEEYPHTFQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIA---------KDNDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIISGFTDSEEKKR--KGILE--------------IESAEVSGNSVVCSFLQYMEKSKPWQKAWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGY--VVD-----EMPRSADLPHSFKLTQSKS--VHSFAADSEELKQKWLKVILLAVTGET 743          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213042|sp|O88387.1|FGD4_RAT (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 4; AltName: Full=Actin filament-binding protein frabin; AltName: Full=FGD1-related F-actin-binding protein)

HSP 1 Score: 242.276 bits (617), Expect = 9.963e-68
Identity = 153/511 (29.94%), Postives = 267/511 (52.25%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRD-LLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPI-KKQNRN-GLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGF 735
            +A ELL +ER YV+ L+L++  F   + E  E +    P E    IF+N+  I  F+   LL + + R++ W    +I DI  K  PFLK+Y  Y++ F +A +  +   ER P+F+ + +E + ++ CG L +  ++L+P+QR+P+Y++ L+ Y+ K SP++ D+ DA ++  I+S AA HSN  IR  +N ++L+ +   +   E +V     LIKEG I K   RN    + YL L  ++L+Y      V   ++      V  ++ +  + + +  ++EEYP  F +    R+  L+A ++ +K EWI++++++++   QR  +F +A+   K +      +        P WI D+ VTMC  C   F+ L +RRHHCR CG V+C  CS  +A L Y   R  +VC  C+QI+    + ++  R  RG+         ++ +  V         EV   L +   +   W+K W  + ++    L+M+ A  D +  +T+ +LG+
Sbjct:  210 IATELLLTERAYVSRLNLLDQVFYCKLLE--EANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKNMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDAPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYC-----VPRFSLVGSKFTVRTRVGIDGMKI-VETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIA--KENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIMSGFAESEEKKR--RGIL--------EIESAEV-----SGNSEVCSFLQYMEKSK-PWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGY 694          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213572|sp|Q7Z6J4.1|FGD2_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 2; AltName: Full=Zinc finger FYVE domain-containing protein 4)

HSP 1 Score: 236.113 bits (601), Expect = 2.443e-66
Identity = 159/572 (27.80%), Postives = 283/572 (49.48%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITE--KIEEDPNIMPLEEFEYIFTNMKEILEFNRDL-LHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMH-ELVQADRGLIKEGPIKKQN--RNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDC---PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKN----WFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDA 785
            + QELL++E+ YV  L L++   +VF  E  K        P +    IF+N+  I +F+    L + + R+++W    +I D+  K  PFLK+YS Y++NF  A++   T  ++ P F+E++   +S E  G L +  ++L+PVQR+P+Y+L L+ Y+ K   ++ D  DA +A  ++  AA HSN  I   +  + L  + +R+ +  ++V     L++EGP+ K +  RN   + YL L  ++L+Y    P VI    +    +V  +I ++ + V+   ++ E+P  F +    R+  L+A+++ E + W+++ + A++   +R  +F +A    +    D ++ + +  +     P W+ D  VTMC  C   F+ L +RRHHCR CG V+C  CS   A L+Y   RP RVC  C+  L  N   +      RG                +L KG     + +    F      KW K+    W  +       L+++ A  D +  +++ +LG+ + + P+          + R FQL+ SG    T+ AE+     +W+ A++ A
Sbjct:  106 IVQELLETEQAYVARLHLLD---QVFFQELLKTARSSKAFPEDVVRVIFSNISSIYQFHSQFFLPELQRRLDDWTANPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWTDKSPLFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQADAQKALDMIFSAAQHSNAAITEMERLQDLWEVYQRLGLEDDIVDPSNTLLREGPVLKISFRRNDPMERYLFLFNNMLLYC--VPRVIQVGAQ---FQVRTRIDVAGMKVRELMDA-EFPHSFLVSGKQRTLELQARSQEEMISWMQAFQAAIDQIEKRNETFKAAA---QGPEGDIQEQELQSEELGLRAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCARCSDYRAELKYDDNRPNRVCLHCYAFLTGNVLPEAKEDKRRG----------------ILEKGSSATPDQSLMCSFLQLIGDKWGKSGPRGWCVIPRDDPLVLYVYAAPQDMRAHTSIPLLGYQVTVGPQG---------DPRVFQLQQSGQL-YTFKAETEELKGRWVKAMERA 639          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|61213586|sp|Q8BY35.1|FGD2_MOUSE (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 2)

HSP 1 Score: 224.942 bits (572), Expect = 2.699e-62
Identity = 159/567 (28.04%), Postives = 284/567 (50.09%), Query Frame = 0

Query:  234 VAQELLDSERRYVNALSLVNYDFRVFITEKIEED--PNIMPLEEFEYIFTNMKEILEFNRDL-LHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMH-ELVQADRGLIKEGPIKKQNRNGLDDI--YLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDAIN 787
            V +ELL++E+ YV  L L++   +VF  E + E       P +  + IF+N+  I  F+    L + + RV++W    +I D+  K  PFLK+YS Y++NF  A++   T +++   F+E+V   +  E    L +  ++L+PVQR+P+Y+L L+ YV K   ++ D  DA RA  ++  AA HSN  I   +  + L  + +R+ +  ++V     L++EGP+ K +    D +  YLVL  ++L+Y    P V+    +    +V  +I ++ + V+   ++ E+P  F +    R+  L+A+++ E + W+++ + A++   +R  +F +AV   +  + + +          P W+ D  VTMC  C   F+ L +RRHHCR CG V+C  CS   A L+Y   RP RVC  C+  L  N          RG+     ++    P  S++     +  ++ G    +S       ++W  +       L+++ A  D K  +++ +LG+ +I  P+          + R FQL+ SG    T+ AES     +W+ A++ A +
Sbjct:  106 VVRELLETEQAYVARLHLLD---QVFFQELLREAGRSKAFPEDVVKLIFSNISSIYRFHAQFFLPELQRRVDDWAATPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWMDKSQPFQEVVTRIQCSEASSSLTLQHHMLEPVQRIPRYELLLKEYVQKLPAQAPDLEDAQRALDMIFSAAQHSNAAIAEMERLQGLWDVYQRLGLEDDIVDPSNTLLREGPVLKISFRRSDPMERYLVLFNNMLLYC--VPRVLQVGAQ---FQVRTRIDVAGMKVRELTDA-EFPHSFLVSGKQRTLELQARSRDEMVSWMQACQAAIDQVEKRSETFKAAVQGPQGDTQEPKPQVEELGLRAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCAKCSDYRAELKYDSNRPNRVCLTCYTFLTGNVLPQGKEDKRRGILEKEASA---APEQSLVC----SFLQLIGDKCSRSLP-----RSWCVIPRDDPLVLYVYAAPQDTKAHTSIPLLGYQVISGPQG---------DPRVFQLQQSGQQ-YTFKAESVELQGRWVTAIKRAAS 641          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|296439343|sp|Q6ZNL6.3|FGD5_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 5; AltName: Full=Zinc finger FYVE domain-containing protein 23)

HSP 1 Score: 217.624 bits (553), Expect = 1.307e-57
Identity = 171/597 (28.64%), Postives = 283/597 (47.40%), Query Frame = 0

Query:  224 EGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIE----EDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPD-ASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRM-DMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADN-SEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDN-DFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSN--------YDKDDSMR--LYRGLFNGRK-NSFVQLPNPSVLRKGRE------------NGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAE--SNADKWINALQDA 785
            EGQ SR A ++AQELL SE+ YV  L  +N DF   +   ++    E  + +  EE     + +  I + ++ +L + ++R+ NW    K+AD+F+ +      ++T++  F        E CL   PR    V+EFE     G       LL+ VQRL QY++ L  Y+N   P+S +Y +   A  ++S+  D +N+ +   +N ++LV ++  +    +L+Q  R  +KEG + K         +L L  D+L+Y         P  +    K   K  L+   ++++    E+ P    I++S     L A +  E+ EW   + +A+ ++ + QA     +  F  HS + R+       + PP  +P   V MC  C  DF  L  RRHHC  CG+++C  CS N+ PL+Y + R  +VCD CF  LK           ++  SM   L    F+G   +S  Q  NPS  +K ++             G  ++G+L         W+K WF +K K L+ + AS+D   + ++ +LGF +  + E G+      E G  F L H  T   ++ AE  ++A +WI A++DA
Sbjct:  888 EGQ-SR-ALVIAQELLSSEKAYVEMLQHLNLDFHGAVMRALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNWESQQKVADVFLAREQGFDHHATHILQFDRYLGLLSENCL-HSPRLAAAVREFEQSVQGGSQTAKHRLLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQGALSLISKVTDRANDSMEQGENLQKLVHIEHSVRGQGDLLQPGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLY-------TYPQKDG---KYRLKNTLAVANMKVSRPVMEKVPYALKIETSESCLMLSASSCAERDEWYGCLSRALPEDYKAQA-----LAAF-HHSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDF-SLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFSGSAFSSVFQSINPSTFKKQKKVPSALTEVAASGEGSAISGYLSRCKRGKRHWKKLWFVIKGKVLYTYMASEDKVALESMPLLGFTIAPEKEEGSS-----EVGPIFHLYHKKTLFYSFKAEDTNSAQRWIEAMEDA 1459          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|28202247|sp|P98174.2|FGD1_HUMAN (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 1; AltName: Full=Faciogenital dysplasia 1 protein; AltName: Full=Rho/Rac guanine nucleotide exchange factor FGD1; Short=Rho/Rac GEF; AltName: Full=Zinc finger FYVE domain-containing protein 3)

HSP 1 Score: 208.379 bits (529), Expect = 4.514e-55
Identity = 166/543 (30.57%), Postives = 263/543 (48.43%), Query Frame = 0

Query:  220 QPSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPN--IMPLEEFEYIFTNMKEILEFNRD-LLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPI-KKQNRNG-LDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDC-------PPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAG 744
            Q S E  + +  F +A ELL +E+ YV+ L L++   +VF    +EE  N    P +    IF+N+  I  F++  LL + + R+E W    +I DI  K  PFLK+Y  Y++NF  A +   T  ER  +F+ ++ E +  E CG L +  ++L+PVQR+P+Y+L L+ Y+ K    S D  DA ++  +++ AA+HSN  IR  +   +L+++   +   E +V   + LIKEG I K   +NG   D YL+L  D L+Y      V    +      V  +I +  + ++ + N    P  F +    RS  L+A+T+ EK +W+++I   +  + Q   +F   ++N    ST+  D D   N          P  I +  VTMC  C   F+ + KRRHHC+ CG V+C  CS   A L Y   R  RVC  C+  L        +   +      R+ S ++           EN   +   LH+       W K WF + E     L+++ A  D K   +L ++GF+ +  PEAG
Sbjct:  363 QESVELTVQQKVFHIANELLQTEKAYVSRLHLLD---QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYC-----VPRLRLLGQKFSVRARIDVDGMELKESSNL-NLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFK--LLN----STNREDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLVYDNNRSNRVCTDCYVALHGVPGSSPACSQH---TPQRRRSILE----KQASVAAENSV-ICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFE-VGPPEAG 881          

BLAST of and ph domain-containing vs. SwissProt
Match: gi|341940697|sp|P52734.2|FGD1_MOUSE (RecName: Full=FYVE, RhoGEF and PH domain-containing protein 1; AltName: Full=Faciogenital dysplasia 1 protein homolog; AltName: Full=Rho/Rac guanine nucleotide exchange factor FGD1; Short=Rho/Rac GEF; AltName: Full=Zinc finger FYVE domain-containing protein 3)

HSP 1 Score: 207.994 bits (528), Expect = 6.283e-55
Identity = 164/544 (30.15%), Postives = 263/544 (48.35%), Query Frame = 0

Query:  220 QPSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPN--IMPLEEFEYIFTNMKEILEFNRD-LLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHE-LVQADRGLIKEGPI-KKQNRNG-LDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCP--------PVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEK---ALFMFKASDDPKPVSTLAILGFDLILDPEAG 744
            Q S E  + +  F +A ELL +E+ YV+ L L++   +VF    +EE  N    P +    IF+N+  I  F++  LL + + R+E W    +I DI  K  PFLK+Y  Y++NF  A +   T  ER  +F+ ++ E +  E CG L +  ++L+PVQR+P+Y+L L+ Y+ K    S D  DA ++  +++ AA+HSN  IR  +   +L+++   +   E +V   + LIKEG I K   +NG   D YL+L  D L+Y      V    +      V  +I +  + ++ + N    P  F +    RS  L+A+T+ EK +W+++I   +  + Q        +  FK  ++  RD++    + P        P  I +  VTMC  C   F+ + KRRHHC+ CG V+C  CS   A L Y   R  RVC  C+  L        +   +      R+ S ++           EN   +   LH+       W K WF + E     L+++ A  D K   +L ++GF+ +  PEAG
Sbjct:  362 QESVELTVQQKVFHIANELLQTEKAYVSRLHLLD---QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYC-----VPRLRLLGQKFSVRARIDVDGMELKESSNL-NMPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQ-------TLETFKLLNSTNRDDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLIYDNNRSNRVCTDCYVALHGAPGSSPACSQH---TPQRRRSILE----KQASVAAENSV-ICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFE-VGPPEAG 880          

BLAST of and ph domain-containing vs. nr
Match: gi|1325334949|ref|XP_023349293.1| (serine/arginine repetitive matrix protein 2-like [Eurytemora affinis])

HSP 1 Score: 417.542 bits (1072), Expect = 1.598e-123
Identity = 227/573 (39.62%), Postives = 341/573 (59.51%), Query Frame = 0

Query:  222 SEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITE-KIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIAD-NSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDAINI 788
            + E +  R  F +A+E++ SER YV+ L ++N +FR F+ + + E    I+P ++F  +F+N+ E++  N DLL DF+ RVENW    KIAD+ V+KGP+LKLY+ Y+++F   +  +E C  RYP+F +LV+EFE    C +L +  Y+LKPVQRLPQY+L LE Y+    P+S D+ D T+A  IVSEAA+H+N  ++  D F+++++LQ R+   EL++  R L+KEG + K +R G    Y +L +D L+Y      +     +N  LKV Y I L+ LTV +      EY  +F+I S+VRSC LRAK   E+ EW++++  A+ED   R+A+F+         +      + +  +  PVWIPD  VTMCQVC  +F+ L  RRHHCR CG+V+C  CS N+APLRY  +   RVCD CF  L+  + +D+ +R      +  ++    +P    L    EN  E++GHL  +     KW+++WF LKE+ L++++AS+D     TL +LG+   L P A   L    E+G  FQL H  +  L + AE+   ADKWI  L  A N+
Sbjct: 1179 TPEQRQQRKLFFIAREIMSSERVYVDVLKILNTEFREFVQKARAESKSGILPDQDFVKLFSNLPELMMLNEDLLRDFETRVENWNTIKKIADVIVRKGPYLKLYTVYIRDFSAMNFHFEECCSRYPKFGKLVKEFEKLPRCQRLRLQHYMLKPVQRLPQYRLLLEDYLKHLDPDSPDFDDTTQALHIVSEAAEHANNTVKQGDKFQRMLKLQSRVGDWELIKPGRELVKEGELSKISRKGFGPRYFILVSDCLLYTSYQGTMAG---DNTSLKVSYSIMLNQLTVNLPPCQDREYNTEFSITSNVRSCTLRAKDVAERNEWLDALNTAIEDYRSRKATFNIG------DTMSLGRGEGKLGESAPVWIPDQRVTMCQVCGGEFN-LVVRRHHCRACGKVVCTNCSRNKAPLRYKGWEQHRVCDTCFDHLEKLHGEDEELRSRFKKRDHSRSVGKYIPQRLKLPANSENS-EMSGHLR-RRLKNNKWKRSWFVLKERVLYIYRASEDTVAAETLPVLGW--TLQPLAEKLLLEPGESG--FQLSHPNSETLIFVAENKTYADKWIAELNIASNL 1735          

BLAST of and ph domain-containing vs. nr
Match: gi|1101351944|ref|XP_018901958.1| (PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6-like isoform X2 [Bemisia tabaci])

HSP 1 Score: 386.726 bits (992), Expect = 6.443e-116
Identity = 213/593 (35.92%), Postives = 349/593 (58.85%), Query Frame = 0

Query:  229 RSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPN--IMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDN--DFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQI---------------------LKSNYDKDDSMRLYRGLFN----GRKNSFVQLPN-PSVLRK--GRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDA 785
            + AFLVA+EL  SE+ ++NALSL+ +DF  FI  K   DP+  ++P  + + +  ++ ++L FN+ LL DF++R++ W    KIAD+ VKKGPFLKLY++Y+++F    +  + C ++Y RF + +++FE  + C KL +  Y+LKPVQR+PQY+L LE Y++   PES DYLD  +A  +V + A+H+N+ ++  D+  +L+++Q ++  +E+V+  R  +KEG + K +R  L   +L+L +D LI       +         LKV Y++PLS + V +   +E+Y  +F+I ++ RS  LRA+T++E+ EW+E++E A+ DN QRQ SF    +N K   T    N  +F+     PVWI D  VTMCQ C  +F   F RRHHCR CG+V+C  CS  +APL+Y +++ +RVC+ CF I                     LKS+   D ++     LF     G    F ++   P  LR+    ++G +++G L ++      W++ WF LK++AL+ +KAS+D   + ++A+LGF +    ++  +L    ++ R FQL H G  P+T+ A++   A +W+  L +A
Sbjct:  525 KKAFLVAKELTTSEKVFINALSLICHDFTAFIN-KASPDPSNPVLPQPDLQKVIGSLPQLLLFNQVLLQDFENRIKTWESQPKIADVIVKKGPFLKLYTSYIKDFQSQCEFLDECCQKYSRFDKALRDFECSDICKKLTLKHYMLKPVQRIPQYRLLLEDYLSNLDPESEDYLDTQQALHVVCDVANHANKSMKQGDHLSKLLQIQAQLGNYEIVKPGREFVKEGDLYKLSRKSLQLRFLILLSDTLILTSYYGSMTG-------LKVNYELPLSGMKVYVP-QTEDYHNEFSIITTTRSFSLRARTQIERQEWVEALESAIRDNIQRQLSF----LNLKAAPTSVTQNGGEFKIGKEAPVWIQDGRVTMCQSCTAEFTVTF-RRHHCRACGKVVCGNCSDYKAPLQYMKFQAERVCEDCFNILIKEFVNPSSQLREAIKKDFNLKSSESVDSALEDIFNLFKRATLGGSKKFKKIQEIPQRLREVTANDSGSQMSGWLLYRKEKRS-WKRFWFVLKDQALYFYKASEDVVALGSIAVLGFKV---EDSQEDLMEVSDSKRVFQLVHPGRKPMTFCADNRDAAKRWMKELHEA 1099          

BLAST of and ph domain-containing vs. nr
Match: gi|1101351942|ref|XP_018901957.1| (PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6-like isoform X1 [Bemisia tabaci])

HSP 1 Score: 386.341 bits (991), Expect = 1.113e-115
Identity = 213/593 (35.92%), Postives = 348/593 (58.68%), Query Frame = 0

Query:  229 RSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPN--IMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDN--DFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQI---------------------LKSNYDKDDSMRLYRGLFN----GRKNSFVQLPN-PSVLRK--GRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDA 785
            + AFLVA+EL  SE+ ++NALSL+ +DF  FI  K   DP+  ++P  + + +  ++ ++L FN+ LL DF++R++ W    KIAD+ VKKGPFLKLY++Y+++F    +  + C ++Y RF + +++FE  + C KL +  Y+LKPVQR+PQY+L LE Y++   PES DYLD  +A  +V + A+H+N+ ++  D+  +L+++Q ++  +E+V+  R  +KEG + K +R  L   +L+L +D LI       +         LKV Y++PLS + V +   +E+Y  +F+I ++ RS  LRA+T++E+ EW+E++E A+ DN QRQ SF    +N K   T    N  +F+     PVWI D  VTMCQ C  +F   F RRHHCR CG+V+C  CS  +APL+Y +++ +RVC+ CF I                     LKS+   D ++     LF     G    F ++   P  LR+    ++G +++G L ++      W++ WF LK++AL+ +KAS+D   + ++A+LGF   ++     +L    ++ R FQL H G  P+T+ A++   A +W+  L +A
Sbjct:  525 KKAFLVAKELTTSEKVFINALSLICHDFTAFIN-KASPDPSNPVLPQPDLQKVIGSLPQLLLFNQVLLQDFENRIKTWESQPKIADVIVKKGPFLKLYTSYIKDFQSQCEFLDECCQKYSRFDKALRDFECSDICKKLTLKHYMLKPVQRIPQYRLLLEDYLSNLDPESEDYLDTQQALHVVCDVANHANKSMKQGDHLSKLLQIQAQLGNYEIVKPGREFVKEGDLYKLSRKSLQLRFLILLSDTLILTSYYGSMTG-------LKVNYELPLSGMKVYVP-QTEDYHNEFSIITTTRSFSLRARTQIERQEWVEALESAIRDNIQRQLSF----LNLKAAPTSVTQNGGEFKIGKEAPVWIQDGRVTMCQSCTAEFTVTF-RRHHCRACGKVVCGNCSDYKAPLQYMKFQAERVCEDCFNILIKEFVNPSSQLREAIKKDFNLKSSESVDSALEDIFNLFKRATLGGSKKFKKIQEIPQRLREVTANDSGSQMSGWLLYRKEKRS-WKRFWFVLKDQALYFYKASEDVVALGSIAVLGFK--VEDSQEQDLMEVSDSKRVFQLVHPGRKPMTFCADNRDAAKRWMKELHEA 1100          

BLAST of and ph domain-containing vs. nr
Match: gi|1227977998|ref|XP_021920543.1| (FYVE, RhoGEF and PH domain-containing protein 6-like isoform X1 [Zootermopsis nevadensis] >gi|1227978000|ref|XP_021920544.1| FYVE, RhoGEF and PH domain-containing protein 6-like isoform X1 [Zootermopsis nevadensis] >gi|1227978002|ref|XP_021920545.1| FYVE, RhoGEF and PH domain-containing protein 6-like isoform X1 [Zootermopsis nevadensis] >gi|1227978004|ref|XP_021920546.1| FYVE, RhoGEF and PH domain-containing protein 6-like isoform X1 [Zootermopsis nevadensis])

HSP 1 Score: 369.007 bits (946), Expect = 3.230e-107
Identity = 211/594 (35.52%), Postives = 337/594 (56.73%), Query Frame = 0

Query:  215 KSSNYQPSEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFI-TEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWR--GKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDKDDSMR--LYRGLFNGRK--NSFVQLPNPSVLRK-------------GRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDA 785
            + +N   S E    + AF +A+EL+ SER +++ L L+N DFR  +     E+   ++P  E + I  ++ ++  FN DLL D K R++NW    KIAD+ V+KGPFLKLY++Y+QNF       E C ++YP+F ++V+EFE+   C KL +  Y+LKPVQR+PQY+L LE Y+   SP S D  D   A  IV + ADH+N  I+  D+  +L++LQ ++  +E+++  R  +K+G + K +R G+   Y +L  D L+Y      V     ++  LK+ Y++PL+++ V I   +E+Y  +F+I S  RS  L A++  E+ EW++++ KA+ D + RQ SF +  +     + D  +  FR     PVWI D  VTMCQ C  +F   F RRHHCR CG+V+C  CS   APL+Y +++  RVC++C   +LK   D    +   + R L N  +  ++F +L  P+  RK               + G +++G L  +S  +  W++ WF LKE+ L+++KAS+D   + ++ +LG+ +    E   +L    +    FQL H G  PL + A+S   A++WI A+ DA
Sbjct:  879 RDANQTQSVETHHEKKAFYIAEELMTSERVFIDVLKLLNVDFRQAVHAVGAEQKYPVIPGAELDKILNSLPQLQSFNEDLLRDLKHRIDNWDCIKKIADVIVRKGPFLKLYTSYIQNFESQCIYLEECCQKYPKFAKVVKEFEASPRCQKLSLKHYMLKPVQRIPQYRLLLEDYLRHLSPSSPDLDDTQTALKIVCDVADHANRSIKQGDHLSKLLQLQSQLGNYEIIKPGRVFLKDGELFKLSRKGVQPRYFILLNDCLLYTSYYGSV-----QSSGLKMNYELPLNSMKVSIP-QAEDYHNEFSIISVKRSFTLSARSLNERQEWVDALHKAITDYTSRQLSFQNIKITSSPKNEDSSE-PFRLGQEAPVWIQDSRVTMCQCCTAEFTVTF-RRHHCRACGKVVCGDCSDFRAPLQYMRFQSARVCEECHNTLLKEATDPTSEVNQAMKRELGNAVRIIDNFKKL-GPASGRKIKKYIPQRLKEVTANDTGSQMSGWLQRRSRRS--WKRLWFVLKEQVLYVYKASEDVVALESIPVLGYAVEPMKERHFQLYEGIDAKLVFQLAHPGQHPLIFHADSEHLANRWIAAMSDA 1461          

BLAST of and ph domain-containing vs. nr
Match: gi|242010240|ref|XP_002425878.1| (FYVE, RhoGEF and PH domain-containing protein, putative [Pediculus humanus corporis] >gi|212509844|gb|EEB13140.1| FYVE, RhoGEF and PH domain-containing protein, putative [Pediculus humanus corporis])

HSP 1 Score: 358.992 bits (920), Expect = 2.479e-106
Identity = 210/569 (36.91%), Postives = 318/569 (55.89%), Query Frame = 0

Query:  228 SRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPN-IMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSN------YDKDDSMRLYRGLFNGRKNSFVQLPNPSVLRKGRENGFE--VNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFE---NGRAFQLEHSGTGPLTYFAES--NADKWIN 780
            S  AFL A+EL+ SE  +++ L L+N DFR F+  K  E  N  +P  E   I  ++ ++   N D+L D + R+ENW    KI+D+ VKKG FLK+Y+TY+QNF   +   + C+ +YP+F +LV+EFES + C KL +  Y+LKPVQR+PQY+L L  Y+      SVDY D   A  IV +  DH+N  I H D   +L+  Q  +  + L++  R LIK+GP++K  R  + D Y +L  D  ++   S            LK+  ++PLS + V + D+ E+Y   F + S  RS  L AKT+ E  +W+E +  A+E++ ++Q +F    +N K   +D     F+     PVW+PD  VTMCQ+C  +F  LF RRHHCR CG+V+C  C SN+APL+Y  ++  RVCDQCF +L         Y K   ++ Y    NG+K  ++    P  L++   N  E  ++G L+ KS  +  W+  W+ LK+  L+++KAS+D   + T+ +LG+++          K  FE       F L HS   PL + AES  +AD+++N
Sbjct:  465 SSRAFLKAKELMTSEEVFIDVLKLLNVDFRNFVQMKNHETKNSCIPNTEVNKILNHLSQLQSLNEDILEDLRKRIENWDTNPKISDVIVKKGAFLKMYTTYIQNFESQTNYLDECMIKYPKFGKLVKEFESSDKCKKLSLKHYMLKPVQRIPQYRLLLNDYLKHLDEGSVDYADTVSALNIVCDVVDHANRNIGHGDKEGRLMHFQSLLGEYALIKPGRALIKDGPLEKICRKSVKDRYFILLNDCFLHTTYSKQY---------LKIHQELPLSGMKVCLNDD-EKYSNSFTVHSIKRSFILCAKTESECKDWVEKLHGAIEEHIKKQKTF----LNVKIEMSD----SFKLGKEAPVWVPDGKVTMCQICTAEFTALF-RRHHCRGCGKVVCRNCGSNQAPLQYTNFKSDRVCDQCFDLLLKGVQNEYLYIKSKFVK-YSSAGNGKKPKYI----PPRLKEVSANDSESSMSGWLYRKSRKS--WKMFWYVLKDHVLYVYKASEDVLALETIPVLGYEV-------ERAKVNFEEIDKNLIFSLVHSSQMPLIFRAESQTSADRYLN 1000          

BLAST of and ph domain-containing vs. nr
Match: gi|939640095|ref|XP_014270844.1| (PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6-like [Halyomorpha halys] >gi|939640097|ref|XP_014270845.1| PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6-like [Halyomorpha halys])

HSP 1 Score: 348.206 bits (892), Expect = 6.692e-106
Identity = 195/579 (33.68%), Postives = 329/579 (56.82%), Query Frame = 0

Query:  231 AFLVAQELLDSERRYVNALSLVNYDFRVFITE-KIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW-RGK-IADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDKDDSM--------RLYRGLFNGRKNSFVQLPNPSVLRK----------GRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDA 785
            A+L+A+EL+ SE+ Y++AL L+ +DF+ +I E  ++ +  I+P  E E IFT + ++L  N DLL+D   R++NW  GK IA++ V+KGPFLKLY+TY+++F +     + C  ++P+F   ++E+E    C KL +  Y+LKP+QR+P Y+L LE Y+     ES +Y D   A  I+ +   H+N  ++  +NF +L ++Q  +  +E+++  R  IKEG +KK +R      +++L +D L+Y   +  V         LKV Y++PLS + VQ  ++++    +F+I ++ RS  LRAK  +E  EW+ ++  A+++N+ RQ SF +   N    S +F     +     P+WI D S TMCQ+C  +F   F RRHHCRCCG+V+C  CS+N+APL Y +++  RVC++CF  +LK   D ++ M        ++        ++SF ++     ++K            ++G  ++G L  K      W++ WF LK++ L+M+KAS D     +L +LG+ +    E  +      +    F+L H+G  P+ + A +   AD W++AL +A
Sbjct:   80 AYLIAKELMTSEQVYIDALKLIVFDFKNYINECNMKNNSVIIPNNELEKIFTTLPQLLHLNEDLLNDLVIRIDNWNEGKGIAEVIVRKGPFLKLYTTYMKDFENQCNYMDECCIKFPKFSNALKEYEKSPICKKLTLKHYMLKPIQRIPHYRLLLEDYLKHLDKESSEYRDTETALNIIRDVLHHANSSLKLVENFYKLYQIQTALGNYEIIKPGRLFIKEGELKKLSRKETQGRFIILLSDCLLYTIYTTSVTG-------LKVKYELPLSGMKVQTHNDTQGVFKEFSIITNTRSFTLRAKNSIEGEEWVNALTTAIKENNSRQLSFLNKTCNVG--SENFE--SLKLGRQAPIWIQDKSTTMCQICTAEFTVTF-RRHHCRCCGKVVCGDCSNNKAPLLYLKFQSARVCEECFNYLLKEFEDPENKMHELIKQELKISDEEVENLRSSFKKMDIVKKVKKFVPQRLKEVMANDSGSSMSGWLCRKH--KKDWKRMWFVLKDQVLYMYKASHDVVAHDSLPVLGYAVERQVEVED-----MDRNLVFRLTHAGQTPVVFSAPNKQFADMWVSALTEA 639          

BLAST of and ph domain-containing vs. nr
Match: gi|1229907263|ref|XP_022174556.1| (FYVE, RhoGEF and PH domain-containing protein 6-like isoform X2 [Myzus persicae])

HSP 1 Score: 353.599 bits (906), Expect = 1.094e-105
Identity = 206/595 (34.62%), Postives = 330/595 (55.46%), Query Frame = 0

Query:  222 SEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTV--QIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDKDDSMRLYRG--------LFNGRKNSFVQ------------LPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDAINIE 789
            +EE      +    +EL+ +E+ +++ L+L+   F +F+ E+   D  ++P  +   I + + ++L  N DLL D ++R++NW    KIAD+ VKKGPFLKLYSTY+QNF   S   +   ++YPRF++ V++FE+ + C KL I  Y+L P+QR+ +Y+L LE Y+      S+DY D   A  IV + A+H+NE ++H D   +L+ LQ  +  + +++  R LIKEG + K +R  +   Y +L  D L+Y      V         LK+ Y++PLS + V   I DN      +F+I +  RS  LRAK+ +E  EW+  +EKA+ +++ +Q SF    +N K  S +      +     P+WI D  VTMCQ C T+F   F RRHHCR CG+V+C +CS N+APLRY +++  RVCD C+  +LK   DK   MR            + +  KNSF +            +P         ++G +++G L ++      W++ WF LKE+ L+M+KAS+D   ++T+ +LG+ +   PE  N     F++   FQL H+G  PL + +++   A +WIN L +A  ++
Sbjct:  268 TEEIPTKAKSLRTVEELISTEKIFIDVLNLLCKTFVMFV-EQTGGDVKLIPSTDLSKIISPLPQLLSLNEDLLQDMENRLKNWNEHPKIADVIVKKGPFLKLYSTYIQNFESQSNLLDEYCQKYPRFQKCVKDFEASDVCKKLTIKHYMLTPIQRITKYRLLLENYLKNQDEGSIDYQDTIIALGIVCDVANHANESMKHGDCVSKLLHLQSLLGSYIIIKPGRELIKEGELYKLSRKDMQLRYFILLNDCLLYTSYYGTVAG-------LKINYELPLSGMKVFLPITDNCLN---EFSIITITRSFTLRAKSAVELKEWVSILEKAIREHTNKQLSF----LNMKFVSKNVGCEPLQLGYEAPIWIQDCRVTMCQSCATEFTVTF-RRHHCRACGKVVCSSCSENKAPLRYMKFQSARVCDDCYDYLLKEFEDKILEMRQSSSNSDFEILKMVDTVKNSFKKSGVWSSKKLVKYVPQRLKEVMANDSGSQMSGWL-YRREKRKSWKRFWFVLKEQVLYMYKASEDVVALNTIPVLGYSVQTFPEGTN--YEEFDSSCVFQLAHAGQNPLIFCSDTEQLAKRWINTLNEATKLK 843          

BLAST of and ph domain-containing vs. nr
Match: gi|1229907261|ref|XP_022174555.1| (FYVE, RhoGEF and PH domain-containing protein 6-like isoform X1 [Myzus persicae])

HSP 1 Score: 353.214 bits (905), Expect = 1.995e-105
Identity = 206/595 (34.62%), Postives = 330/595 (55.46%), Query Frame = 0

Query:  222 SEEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFITEKIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENW--RGKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTV--QIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQ-ILKSNYDKDDSMRLYRG--------LFNGRKNSFVQ------------LPNPSVLRKGRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAESN--ADKWINALQDAINIE 789
            +EE      +    +EL+ +E+ +++ L+L+   F +F+ E+   D  ++P  +   I + + ++L  N DLL D ++R++NW    KIAD+ VKKGPFLKLYSTY+QNF   S   +   ++YPRF++ V++FE+ + C KL I  Y+L P+QR+ +Y+L LE Y+      S+DY D   A  IV + A+H+NE ++H D   +L+ LQ  +  + +++  R LIKEG + K +R  +   Y +L  D L+Y      V         LK+ Y++PLS + V   I DN      +F+I +  RS  LRAK+ +E  EW+  +EKA+ +++ +Q SF    +N K  S +      +     P+WI D  VTMCQ C T+F   F RRHHCR CG+V+C +CS N+APLRY +++  RVCD C+  +LK   DK   MR            + +  KNSF +            +P         ++G +++G L ++      W++ WF LKE+ L+M+KAS+D   ++T+ +LG+ +   PE  N     F++   FQL H+G  PL + +++   A +WIN L +A  ++
Sbjct:  287 TEEIPTKAKSLRTVEELISTEKIFIDVLNLLCKTFVMFV-EQTGGDVKLIPSTDLSKIISPLPQLLSLNEDLLQDMENRLKNWNEHPKIADVIVKKGPFLKLYSTYIQNFESQSNLLDEYCQKYPRFQKCVKDFEASDVCKKLTIKHYMLTPIQRITKYRLLLENYLKNQDEGSIDYQDTIIALGIVCDVANHANESMKHGDCVSKLLHLQSLLGSYIIIKPGRELIKEGELYKLSRKDMQLRYFILLNDCLLYTSYYGTVAG-------LKINYELPLSGMKVFLPITDNCLN---EFSIITITRSFTLRAKSAVELKEWVSILEKAIREHTNKQLSF----LNMKFVSKNVGCEPLQLGYEAPIWIQDCRVTMCQSCATEFTVTF-RRHHCRACGKVVCSSCSENKAPLRYMKFQSARVCDDCYDYLLKEFEDKILEMRQSSSNSDFEILKMVDTVKNSFKKSGVWSSKKLVKYVPQRLKEVMANDSGSQMSGWL-YRREKRKSWKRFWFVLKEQVLYMYKASEDVVALNTIPVLGYSVQTFPEGTN--YEEFDSSCVFQLAHAGQNPLIFCSDTEQLAKRWINTLNEATKLK 862          

BLAST of and ph domain-containing vs. nr
Match: gi|939253069|ref|XP_014246195.1| (FYVE, RhoGEF and PH domain-containing protein 6-like isoform X2 [Cimex lectularius])

HSP 1 Score: 341.273 bits (874), Expect = 2.967e-102
Identity = 196/595 (32.94%), Postives = 321/595 (53.95%), Query Frame = 0

Query:  223 EEGQMSRSAFLVAQELLDSERRYVNALSLVNYDFRVFI-TEKIEEDPN-IMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWRG--KIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRMDMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHSTDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNYDKDDSMRLYRGL--------------FNGRKNSFVQLPNPSVLRK----------GRENGFEVNGHLHFKSTTTGK--WRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAES--NADKWINALQDA 785
            +E    + AF++A+E + SE+ Y+NAL L+ + F   + T  I  +   ++ L +   I T + ++   N +LL D + R++NW    KIAD+ VKKGPFLKLYSTY++NF       + C  +YP+F + + EFE+ E C KL +  Y+LKPVQR+PQY+L LE+Y+ +   +S +Y D   A  IV +   H+N  I+  DN  +L+++Q  +  +E+++  R  IKEG + K +R  +   Y VL +D L+Y   S  +         L+V Y++ LS + V      +    +F+I +S RS  LRA+T+ E  +W+ ++  A+++N+QRQ +F    ++ K           +     PVWI D   TMCQ+C  +F   F RRHHCRCCG+V+C  CS+N+APL+Y +++  RVC++C+  L   ++ D + +++  +                  K SF +       +K            + G +++G L+ K    GK  W++ WF LKEK L+++KAS D     ++ +LG+ +    E G+E     ++   F L H G   L + + S   A+ WI AL++A
Sbjct:  154 KENSKQKDAFMIAKEFMTSEKVYLNALHLIVFHFTEHLKTYAINNNCGAVISLTDLSKIITTLPQLQSLNENLLTDIELRIKNWSHLPKIADVIVKKGPFLKLYSTYIKNFESTCTFLDECCVKYPKFAKALNEFENSEICKKLTLKHYMLKPVQRVPQYRLLLEKYLEQIDEDSTEYADTKSALAIVEDVLHHANSSIKLGDNLSKLLQIQFSLGGYEIIKPGREFIKEGELYKLSRKEMQLRYFVLLSDCLLYTTYSSSI-------SGLRVKYELQLSGMKVY---KHQMDILEFSIITSTRSFTLRARTEEECADWLNALLSAIKENNQRQLTF----LSMKCMDKSITFETLKLGKEAPVWIQDKKTTMCQICTAEFTVTF-RRHHCRCCGKVVCGTCSNNKAPLQYLKFQSARVCEECYDYLLKEFE-DPANKIFENVKAELQLSDDETAVTLENLKASFKKFDCAKKTKKFIPQRLKEVTANDTGSQMSGWLYRK----GKRGWKRQWFVLKEKILYVYKASHDVVAYQSIPVLGYTIDQSSEVGSE---EIDSNLVFSLNHPGQSSLIFSSPSKQTAEMWITALKEA 725          

BLAST of and ph domain-containing vs. nr
Match: gi|926622000|ref|XP_013776366.1| (uncharacterized protein LOC106461121 [Limulus polyphemus])

HSP 1 Score: 353.214 bits (905), Expect = 8.433e-102
Identity = 201/601 (33.44%), Postives = 337/601 (56.07%), Query Frame = 0

Query:  229 RSAFLVAQELLDSERRYVNALSLVNYDFRVFITE-KIEEDPNIMPLEEFEYIFTNMKEILEFNRDLLHDFKDRVENWR--GKIADIFVKKGPFLKLYSTYLQNFPDASKAYETCLERYPRFRELVQEFESRETCGKLHISSYLLKPVQRLPQYKLFLERYVNKSSPESVDYLDATRACLIVSEAADHSNEMIRHDDNFRQLVRLQRRM-DMHELVQADRGLIKEGPIKKQNRNGLDDIYLVLCTDLLIYARISPGVINPNIENDPLKVIYKIPLSTLTVQIADNSEEYPCDFNIKSSVRSCRLRAKTKLEKLEWIESIEKAMEDNSQRQASFSSAVVNFKRHS-----TDFRDNDFRGNDCPPVWIPDDSVTMCQVCFTDFHKLFKRRHHCRCCGRVLCHACSSNEAPLRYCQYRPQRVCDQCFQILKSNY---------------------DKDDSMRLYRGLF------NGRKNSFVQLPNPSVLRK--GRENGFEVNGHLHFKSTTTGKWRKNWFGLKEKALFMFKASDDPKPVSTLAILGFDLILDPEAGNELKSTFENGRAFQLEHSGTGPLTYFAE--SNADKWINALQDAINIE 789
            R  F +AQE++ SE+ +V+ L L+N DFR  + E + E+  +I+P E    +     ++   N +LL + ++R+E+W   G+I+DI V  GPFLKLYS Y+++F      +E C ++YP F ++V+EFE    C +L ++ Y+LKPVQR+PQY+L L+ Y++    +S DY D   A  I+S+ ADH+NE ++ +DN  +L+ +Q R+   HE+++  R  IKEG + K +R  +   + +L +D L+Y           ++N+  +V +++ L+ + V I    ++Y  +F+I S  RS  L A +  E+ +WI ++  A+E+N+ ++++F     N   H      T   +  F      P+WIPD  VTMCQ+C ++F   F RRHHCR CG+V+C ACS++ APLRY  +RP RVCD+CF  L+  +                     D   SM   +  F       G+K   ++   PSVL++    + G   +G+L  +      W++ WF +K+K L+M+KAS+D   ++++ +LG+ +    E  +E+    E    FQL H G  P+ + A+  S+A++WI A+++A  +E
Sbjct:  797 RRVFYIAQEIMTSEKLFVDVLRLLNEDFRKAVGEAEREQGTSIIPEEILNQLLKYFPQLQNLNENLLRELQERIEHWPEIGRISDILVTLGPFLKLYSAYIRDFESTINLFEECKKKYPLFSQVVKEFEMNPRCQRLSLNHYMLKPVQRIPQYRLLLQDYLHHLHIDSPDYEDTVAALEIMSQVADHANETMKQEDNLSKLITIQNRIFGHHEVIRPGRVFIKEGELMKLSRKIMQPRWFILFSDSLLYMT--------KVQNNLYRVNHELQLTGMRVSIPIQ-QDYQNEFSIVSVTRSFSLAASSPEERDQWINALSHAIEENACKRSTFQ----NIHHHQKSGEETPLENTGFELGQRAPIWIPDVRVTMCQLCTSEFTVTF-RRHHCRACGKVVCSACSASRAPLRYLGFRPVRVCDECFPKLRQEFTEYSVGGGDSGGASESADTESDTPHSMADLKAQFKENLRHTGKK---IKRNLPSVLKEVSANDQGSSNSGYLQRRGRRG--WKRYWFVIKDKVLYMYKASEDVAALASIPLLGYTVDTFTEEIDEV----EGNLLFQLTHPGQPPVLFHADTPSSAERWIRAMEEATVLE 1374