Query:   22 WKKRPPGPWVFPFMGSIPALGK---ADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGV-IFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSG--SKLGDESATLDPVGGLTIGPKKYMATVQ 494
            W   PPGP  +PF+G+IP+L K       AL+ P     +L   YG    +  G +  +IL+ L  I++FS       RP  K L +IYS  + LG+ +   G  WK  R+F     +    G   +  +   E+   +  LR +          +  +F++P LN+IW LV GRR+ YGD  + +  ++++    E  I P+  I +  YIPP  +IY RI   M  F+  LS  V+E +    TD  RG+ID FL+AQ   ++   Y S++ L++  QDFF  G+ T SKTL   IL+MV YP +QE A  EI+DA+    ++   DR  LP+ +A++MEV+R ++  PI P R   KD+ +          VQ+NL  + R++  W  PD F P RF+N K GAVE      PFG+G+R+C+GE +   +  L ++N L  FKFS   SK  +   + D  GG+  G + +   ++
Sbjct:   32 WSNAPPGPSTYPFLGAIPSLVKDFWGSDRALKSPIDFFDKLHDIYGEDFRLHNGIEDTIILSSLNGIREFSNHPNASFRPFNKVLMDIYSDGKDLGMGLGTGGERWKFLRRFSSSAFKSLSGGASGLNQNFDLEVSEIVAXLRGKAKSPDPIIRNVNIYFDIPILNIIWWLVAGRRYKYGDPAIQKQFDYLKVLLEEPFIAPLTIIPFALYIPPLRKIYNRIRNAMNSFRILLSKIVEERRKDNFTDEKRGFIDLFLKAQLDDKD-NPYLSNEDLIMCCQDFFLAGAETSSKTLCTFILYMVLYPNIQENAASEIRDAIQKDTQIKSKDRHLLPYTDAVLMEVRRYATPFPITPFRCSNKDIRVNGFDXPANVPVQVNLNGVLRSKYCWKAPDIFNPSRFLNEK-GAVEIPNAFMPFGFGRRRCIGEDIGNISNFLIVSNLLHNFKFSASFSKNKNHLPSNDRFGGIIQGYEPFDVKIE 508          

Query:   24 KRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHK--HMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVG---GLTIGPKKYMATVQ 494
            K PPGP   P +G++P +    +NAL  P          YG + S+ +G    V++   +  K     ++   R        +     PLG+I   G +WKEQR+F +R L++FG GK T++  IQ+E + +I+ + ++ ++N N  + M+  FN+  +N++W+++ G RFD  +++  E++ H+     E       G S L YIP      KR  +   M   KEF  + ++E          R +ID +++      E  E F ++QL+ +  DFF  G  T + TL +++L++  YPE Q +  +EI+  LG  D  +     ++ +  A +ME+QR++SV P+  P V +KD+ I  + I +GT++  N+ + H N + +  P SFRP+RFI  + G ++  E   PFG GKR C+GE++AK+ + +F    L K K S   + +     DP     G+T  PK +  +V 
Sbjct:   25 KFPPGPPNLPIVGTLPYMNGIGSNALTDPKFGK------YGDLYSLFIGNIHLVVINNYQLAKDLFAREDVSYRRETWWTLNVRGDGHPLGIINTSGHVWKEQRRFAVRNLKDFGFGKNTLDAVIQNEARFTIEDIIKE-SKNNNGVLRMESTFNVGIINILWQIIAGYRFDKDNEKTKEMMGHLHEVYSE-------GYSILHYIPAARFFIKRDKRMDDMLRTKEFFRSQIREHMKDYDASNPRDFIDVYIKEMLD--EDRENFHEEQLMTTCLDFFQAGGETSATTLLWSVLYISLYPEAQAKCVEEIEAVLGKEDP-SQEVYKDMVYCNATLMEIQRMASVGPLTLPHVTIKDLFIDGYCIPRGTEIYGNIIAFHNNPKFFPSPKSFRPERFI--ENGKLKKLEAFAPFGVGKRICMGESMAKNQLFIFFVMMLQKLKIS---VSENHGVPDPEAYTMGITKIPKPFYISVS 478          

Query:    5 LGLFIVICLYTYVPLF--KWK---KRPPGP-WVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVAR-------PNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGP-IAGI-SYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQ--------QLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRD-----EVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLK-DVMIGDHMITQGTQVQINLYSLHRNQEHWG-DPDSFRPDRFINPKT-GAVE--PDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKY 489
            + L I +CL     L+  KWK     PP P +  P  G    L  A  N  E   R   R + G G +      +    +++  + +K+    D+   R          K LY+    D   G ++  G +WK+QR+FM+ TL+ FG G+ +MED + +E    + FL E+ N      + + + FN+  LNV+WR+V G RF+Y D  L +++  +    +   + P IA I  +L+ I P     + +   +    EFL   V+  +A+   +  R +ID++L       E  +  +D          L  ++ D F  GS T S TL++ +LFMV++PE+Q++ ++E+   L   D     +    DR  LP+ EA + E+QR  ++ P+  P      D  +GD+++ +G  V   L  + RN +++G +PD F PDRF+   + G V+   +E+L PF  GKR C GE +A+  +  F  + L +F+     +  E  + D + G+T  PK +
Sbjct:    3 VALVITVCLILAXILYEIKWKYPENYPPTPPFRLPLFGHSLYLRSAGKNFQEGFDRIFDRFNVG-GVLCLQVAARIRMXMISDFDILKKILKTDDLNYRLAHDFSIDYTKKLYQGIGVD---GXLWSYGXIWKQQRRFMLSTLKNFGFGRSSMEDMLMEEATLFVNFLNEE-NIQTGGNIRIANLFNIGILNVLWRIVAGTRFEYRDPELQKIVHKVGDAILSTNLKPTIAAIFPFLRTIYPGIDDXQEVTSKVAAVYEFLQTAVKNHEANFDPNHPRDFIDTYLLKIKDSEENPDKENDSFRGELGKLNLSKTLLDLFFAGSETTSSTLSWGVLFMVRHPEIQKKVQEELDLFLHEGDGESFRKARSEDRIHLPYTEAXICEIQRRGNITPMGVPHATYSGDAKVGDYVVPKGHVVNAYLSGIFRNPKYFGPNPDQFNPDRFLEVASDGGVKFIKNEYLIPFSIGKRSCPGENLARMEIFSFFTSILQRFELRS--IDGEIPSTDFISGITSIPKPF 513          

Query:   21 KWKKR-PPGPWVFPFMGSIPAL-GKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDR-PLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHM-ETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKH--MGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFS 465
            +W  R PPGP   P +GSIP + G      L   YR        +G + ++ +G    +++   +  K+  + +E  +R +      +    +  LG+I   G  W+ QR+F +R LREFG GK++++  IQ+E + SI  + ++ ++N + +V M   FN+  +NV+W++V G+RFD  +    E +EH+ E F +        G S L Y+P      K+  +   M   KEF    ++E       D  R +ID +L+   +  E   YF  +QL                               +Q++ ++EI+D L   ++ T    +ELP+  A +MEVQRL+SV P++ PR   KD+ +  + I +GT++  N  + HR+ + + +P  F+P+RF+      V+ DE   PFG G+R C+GE++A+H +++F    L     S
Sbjct:   10 RWVARFPPGPRNLPLVGSIPFMNGIGTQGCLNPDYRK-------FGDLYTLFIGPIPLIVINSFQLTKELYVKEEISSRRDTWWTINVRGDGKQSLGIINTGGMKWQTQRRFALRQLREFGFGKRSLDSVIQEEAQASIDTILQESSKN-DGKVLMASNFNVSIINVLWQIVAGQRFDPEESSTKERMEHLNEVFRV--------GYSVLHYLPIARYFIKKDERRDKMLSLKEFFREMIREHIKDQDDDNPRDFIDVYLKEVHKSGEKPSYFHIEQL-------------------------------IQKKCKEEIKDKLQGDEKPTQDCISELPYTHATLMEVQRLASVGPMSLPRYTTKDIDVNGYSIPEGTEIYSNFMAFHRDPDFFPEPLEFKPERFLTEDGSRVKKDEHFLPFGLGRRICMGESLARHQLIIFFIMILQNLNIS 413          

Query:    7 LFIVICLYTYVPLFK-----WKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRT---LREFGLGKQTMEDHIQDEIKCSIQ-FLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELI----EHMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGE-YFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMATVQ 494
            L ++I   T + + K     +K  PPGP  +P +G IP L K + + L F Y      +  +G I+S+ +G +  V+L+  + IK+        ARP      E+       G++  +GPLWK QRK+++     ++ +  G  ++E  I+  +   +Q FL    N+ +N  V +   FN    NVI  ++  RRF Y D +    +    E    FTM    G +  + +LK +P  S    ++ ++      F+   + E +  L     +  IDS+L  ++   +  E Y  +QQL   + D F+    T   +L +AI+FM+  P++  + R E+   +G  +   L D  +LP+  A + E+ R SSV+P+       ++V     ++ Q + V   ++++H N ++W +P+ FRP+RFIN K G +   E   PFG G+RKCLG+ +A+    LF  + +  F   G+       +L    G+T+ P ++   ++
Sbjct:   15 LIVLIAFLTLLYILKHLKKSFKDLPPGPIGYPIVGIIP-LIKKEFHLLLFDY------AMKFGKIVSLKMGGETVVVLSDYQTIKKAFSCKYFSARPKT----ELSQLLGGYGIVNSEGPLWKTQRKYLLNQKLGMKHWKSGAGSLE-QIESVVSREVQSFLYTLENDYSNTFVNLTPLFNCAVSNVICSIIXSRRFRYQDPKFQRFMFLFDEGFRLFTM---TGAMTFLPFLKVLPGISDTCTKLRQNREEMIAFVREIISEHRQELDPQNPKDLIDSYLVQESTPDQFFEDYDPEQQLEQIILDLFSASVETTRTSLLWAIVFMLHNPKILSKVRDELNSVVGEDNLPQLSDMIKLPYTRATLYEIMRRSSVVPMGTTHATDREVQFEGFVLPQNSHVIPLIHAVHMNPKNWENPEEFRPERFIN-KEGVLFKPEHFMPFGVGQRKCLGDRLAEQEFFLFFTSLVHVFDL-GNNPEQTMPSLRGTAGVTVTPSEFSVHIK 499          

Query:   26 PPGPWVFPFMGSIPALG-KADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYE--IYSFDR-----PLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGIS-YLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGS---RDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLA----NFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMATVQ 494
            PPGP+  P +GS+P L  +     L+F       L + +G I ++       VI + +  +  F M  +   R ++   Y+   + F +       G+I  +GP+W+ QR+F +  L+  G GK+++E  I +E+    + + E  +  +  +V + D F++P +NV+W ++   RF+Y   R  E++E +    +++ I     IS +  Y+P          + M   K F+S    E K +L  +  + +ID +L    + ++   YFS +QL++ + DFF  GS T S TL + IL M  + ++Q +  +EI   +G+   R+E    D   LPF  A + EVQR +++ P +     L+ + +G ++I +GT V  N +  H + + +  P  F P RF       V   E   P+G+GKR C+G+++AK  +  F      N++++      +   +  T+    G+T  P  +   +Q
Sbjct:   30 PPGPFSLPLVGSLPFLSSQGSPGILDF------ALGEKFGSIYTVD------VIWSKIVVLNDFGMAKDLFNREDVSGRYQGQWHRFTKGYDGIAYGIINNEGPMWQSQRRFALTNLKNLGFGKKSLESVIYNEVHHLFEVIDEMIDGCS--DVLIHDIFHVPIINVLWSIIASHRFEYSQAR--EIVEKL-GLDLKKGIHINIFISIFANYVP-----LNESDEAMLYMKRFISKNXDEHKNNLEVNAPKDFIDFYLIEMLKSQDP--YFSKKQLIVMLFDFFLAGSETTSTTLLWIILLMCLHNDIQLKCYQEISQNIGNNFPREE----DMKMLPFTLATISEVQRYANIAPASLVHKVLQTIRVGKYLIPKGTSVIANYHKFHMDPKVFPHPHEFNPYRFY-----KVPKPEQFVPYGFGKRICMGKSLAKKQLFYFFVMIVQNYIIRVPKDNPRPDPKKCTM----GITSVPDPFYVNIQ 477          

Query:  114 GVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDY---GDKRLAELIEHMETFTMEQAIGPIAGISYLK--YIPPFSQI--YKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKF 462
            G+   +G LW+ QR+F +  L+  G GK+++E  I ++I    + +  Q  +++ +++ ++D F +P +NV+W++V  + +D+   G++++              A+  + G +Y    ++  F     Y    K     ++ +   + E   +L  +    ++D +L    +  ++   FS +QL     D F  G+ T + TL +A+L+M  Y  VQE+  +EI   LGSR      D   LP+  A + E+QRL +  P + P   LKD+ IGD+++ +GT    NL   H +   + +P  F PDR+++ K+    P +++ PFG+GKR C+G ++AK  +  F    +  F
Sbjct:   16 GIASSEGILWQNQRRFSLMKLKNLGFGKKSIEIIIYEQIINLFEMIETQ--KDSFNDLFIKDIFTIPVVNVLWKIVASKSYDWRNSGERKVX------------AAVNEVFGAAYETNFFLEKFRHFLPYDIADKSTLKLRQIMEELIDEHTQNLDENSPNDFMDVYLIEMKKNVDST--FSKKQLASLCIDLFLAGAETTNTTLVWALLYMSLYEGVQEKCAEEINSVLGSRMPQE-EDMKNLPYTIATLNEIQRLCNTAPASLPHKNLKDIKIGDYVVPKGTLFLANLIGFHHDPNIFENPQQFNPDRWLHYKSC---PQQFV-PFGFGKRICMGVSLAKKELYYFFVMLIKMF 350          

Query:   26 PPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQ--FSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFF----NL---PCL-----NVIWRLVCG-RRFDYGDKRLAELIEHMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFL 459
            PPGP+ +P +GS+  L     N  + P+ A  +L + YG I S+ +G    V++ G E  K+   +  D    RPN         F R   V F D    +E+R+   + +++F + K             S+  L   C E  NH +   + F    N+    C+     NV  R  C    F Y DK     I   +    E   G +     + + P  S     + + +    +F+ +FV E K  L+  FD  +++++ R +           +++L++   +   GG   ++  +   ++ ++++ ++++  +KEIQ        +T  +   +  + A   E  RL+   PI P R   +D  IG++ +   T + IN + L+ +   W +P ++ P RFI+ +TG +      QPF  G+R C+G  + +      +A+ L
Sbjct:   17 PPGPFGWPLIGSLHLL----KNYEKIPFEAFTKLRKIYGDIFSIRIGSFNCVVVNGNELTKEVLLAKADHFSDRPN---------FHR-FPVAFCDSSFLQEERR---KLIKKFTIPKSH---------SLSLDRLDRLCQEELNHMILQFNMFKNWTNIDLKSCISKATANVFIRYFCSIHSFSYDDKLFNSFILSYDAIFWEVNNGRL-----MDFFPWTSLFAGFVQQPLNSHCKFIRSFV-ENKILLNQKFDDDFLNTYQRIE----------KNKELILFALEDLIGGHSAVTNVILRILVHILEHGDIKKELQKEIQPF----QALTFKETRNMVLLNACFYETVRLTCS-PIIPHRSK-RDTSIGNYCVKNDTVIFINNHFLNYSPSLWYEPLNYNPKRFIDTETGFLSIPAHFQPFSIGRRSCVGYKLTQLICTFSVAHIL 417          

Query:   85 IKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHM-----ETFTMEQAIGPIAGISY------LKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGRE-AGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPP-RVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFK 463
            IKQF+    T+ +            D+ L +   DG LWK  RK +       G  K+ ME  + D     + ++  Q +E  +  + +QD F    L++I     G + +  ++   EL+ H      ++F  +  I  +  + +       KY+  F +    + K        ++N + E + S + +  + +++  ++ + +  E      +D+ +      FF  G  T S TL      +  +PE+QE+  KEI   + S D+    D +E  +  A++ E  R+    P+A   RV  KD  +    I +GT +++ +Y+ H N E + +P+ F+P+RF       + P+ + +PFG G R C+    A     L L   + KF+
Sbjct:  104 IKQFNHFHRTMHKIK----------DKNLLLTLSDGSLWKLLRKDITPVFTS-GKLKEMMEP-VSDIANQFVAYIETQSSEGKS--IKIQDKFQGLTLDIINACAYGIKTNSSEEPDHELLRHSKMLLNDSFITKNVITSVLILLFNSFPGMFKYVDMFGKANDELIK--------IANSIIETRESHNIE-KKDFLNVLVQMRKKSHEDPNTLLNDEIITAQAIIFFIAGYSTTSTTLCCLTYMLATHPEIQEKLYKEI---VSSEDK----DFSEHSYTSAVIKETLRMYP--PVALHLRVCAKDTEVEGIPIKKGTIIEMPIYASHYNPEFFPNPNEFKPERFFQENNLEIIPNTY-RPFGNGNRSCIAYRFAMMEXQLILEKLVKKFE 462          

Query:   27 PGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQG----YGPIMSMGLGQDMWVI-LTGLEEIKQF--SMMDETVARPNLKSLYEIYSFDRP-----LGVIFPDGPLWKEQRKFMMRTLREFGLGKQTME--DHIQDEIKCSIQFLREQCNENANHEVAMQDFFNL---PCLNVIWRLVCGRRFDY-------GDKRLAELIEHMETFTMEQAIGPIAGISYLKYIP-PFSQIYKRIHKH----MGIFKEFLS-NFVQE----EKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAP--PRVPLKDVMIGD-HMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPK-------TGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDES 473
            PGP  FP  GS  +   +D     +     H  ++     YGP++   +  +  +I L   EEI++   S     +  PN   +Y  Y   RP     +G++  +GP W   R  + + L +       +   + I D++   I+  R Q     N +  ++DF ++     L  +  +   RR  +          R+   I+  ++ + E     + G  +  Y+P  FS  +  + KH     G F   +  N VQ     ++ S+      G +D                  + +  SV D+ T G  T+  T+ +A+L + KYPE Q++ + EI+  LGS + +T  +  E+ +++  V E  RL    P A    R+  ++++  + H +  G+ V  +       ++++     F P+R++  +       T        + PFG+GKR C G+ +A+  + +  A  +  F     +L D S
Sbjct:   70 PGPRAFPIFGS--SWQYSDWWFGMYKMEKYHESNEDKYARYGPVVRENVLWNFPLIHLFEKEEIEKVLNSKSKYPLRPPNEADVY--YRNSRPELYNNIGMVNLNGPSWHTLRSTLTKPLTKSSTITNYVAHMNLIADDLTSLIK--RRQ-----NEQGIIKDFQDIVYRAGLETVCTVALERRMGFLADTIALDTARILNAIQGYQSSSNES----MYGXPWWXYVPETFSGXFTSLVKHKDYLFGTFGAMIDENLVQNKDFCDEESIIHQLVSGNVDI-----------------KDVKASVVDYITAGVDTIGNTVIFALLLLAKYPEKQKKLQAEIERVLGSENYITKENIQEMKYLKGCVNESFRL---YPTASQIARILDEEIITSNGHSLPPGSVVLCHQRIASLQEQNFTRAKEFIPERWLEXEAVTEFGTTNYAHNKSLVMPFGFGKRICPGKKLAEQEIYIMTAKLMKNFNL---RLHDAS 522          

Query:    3 LFLGLFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIE--HMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGR-EAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDES--ATLDPVGGLTIGPKKYMATV 493
            + + L ++I     + + K +  PPGP   P +GS     + + + + + +     LS  YGP+  M LG D  V+  G + I+   + DE   RP+    + + +F + +GV+F DGP+W+EQR+F M+ LR+ GLG ++ME HI++E +  +  L  + N      + M D F++  LN +W ++ G RFD  D+RL +L++  H     ++ + G +  +  L++I P    Y  +  H+     FL   + + + S + D  R  ID FLR     + +    F D QLV    D F  GS T S TL +A+L+M+ YP+VQ R + E+   +G+  + TL DR  L ++EA++ME+QR +++ P   P   LK+ ++  H I +GT V ++++SLHR+ +HWGDP+ FRP+RFI+   G ++ D+W  PFG GKR+C+GET+AK ++ LF +  L  F    S    ES   +L+   G+T+ PK + A +
Sbjct:    1 MVIALIVIIIFLVCLDVIKPRGYPPGPVWLPVVGSYLWF-RREKSRVGYYHLVWSSLSSRYGPVTGMRLGTDYIVVACGYDAIRDILLRDEFDGRPD-GYFFRLRTFGKRMGVVFTDGPVWQEQRRFCMQHLRKLGLGSRSMEAHIEEEARDLVASLHRRSNGGLT-AIPMHDVFDICVLNSLWAMLAGHRFDLDDQRLVDLLDIVHKCFRMIDPSGGLLNQMPPLRFIAPRHSGYTNLMTHLNRIWNFLRETIDDHRKSFNADNMRDLIDLFLREMETSKCQNNSSFEDLQLVSLCLDLFMAGSETTSNTLGFAVLYMLLYPQVQRRVQDELDRCVGTDRQPTLQDRRSLRYLEAVLMEIQRHATIAPSGIPHKALKNTVLMGHTIPKGTTVLVSMWSLHRDVQHWGDPEVFRPERFIS-GNGNIKQDDWFMPFGIGKRRCIGETLAKASLFLFFSTLLHNFSILPSS---ESPLPSLEGYDGVTLSPKPFSAKL 489          

Query:    3 LFLGLFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQ-FSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIE------HMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGP 486
            L +     + L  Y    + K  PPGPW  PF+G+I  L          P+ ++  L + YG I S+ LG    V++TGL  IK+  + M++ +    L  + E  S     G+IF  G +WKEQR+F + TLR FGLGK+++E+ +Q+E    ++ +RE+  +  N   ++ +  +    N+I  +  G RFDY D R  E++       ++ET  + Q       I  +KYIP   Q   ++ ++    K F+S  + + +   + D  R +ID+FL+   +  E    F+++ L+ S  D F  G+ T S TL +A+L+M  YPEVQE+ + EI   +G +    L DR  +P+  A++ EVQR+ +++P+  PR    D  +    + +GT V  NL +LHR+ + W  PD F P+ F+  + G  +  E   PF  GKR CLGE +A+  + +F  + + KF F+     +E  +     GLT+ P
Sbjct:   21 LLVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQ------PHLSIQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKN--GLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVS----NIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWI--MKYIPGSHQ---KVFRNWEKLKLFVSCMIDDHRKDWNPDEPRDFIDAFLKEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFL--ENGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPI--NEKLSPKFRNGLTLSP 490          

Query:    7 LFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQ-FSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGISY------LKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKY 489
            LF++  L +  P    K  PPGPW  PF+G+   +     + +      + +  + YG + S+ LGQ   V+++GL  IK+ F+ +D+      +  + E  +     G++  +G  WKEQR+  +  LR FGLGK+++E+ IQ+E    ++ +RE+  +  N  + + +  +    N+I  +  G RFDY D +  EL++ ++  TM   +G  AG  Y      +KY+P     +++I ++ G  K F+S+ V++ +   + D  R +ID+FL    +  +    F+++ L+ +  D F GG+ T S TL +A+L+M  YPE+QE  + EI   +G + +V+L DR  +P+  A++ EVQR+ +++P+   R    D       + +GT +  NL +LHR+ + W  P+ F P+ F+  + G  +  E   PF  GKR CLGE +AK  + +F +  + KF F      +E  +L    GL + P  Y
Sbjct:   29 LFLINILRSRHP----KNYPPGPWRLPFVGNFFQIDTKQTHLV------LQQFVKKYGNVFSLELGQSPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERITGKN--GLVVSNGQTWKEQRRLALMALRNFGLGKKSLEERIQEETHHLVEAIREEGGQPFNPHLKLINAVS----NIICSVTFGERFDYEDCQFQELLQLLDE-TM-HLMGSSAGQLYNGFPCIMKYLP---GPHQKIFRNWGKLKLFVSHIVKKHEKDWNPDEPRDFIDAFLIEMQKDPDRTTSFNEENLISTTLDLFLGGTETTSSTLRWALLYMSSYPEIQENVQAEIDRVIGHKRQVSLSDRESMPYTNAVIHEVQRMGNIVPLNSSREVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATPEVFNPEHFL--ENGQFKKRESFLPFSMGKRACLGEQLAKSELFIFFSALMQKFTFKPPI--NEKLSLKFRMGLILSPASY 493          

Query:    8 FIVICLYTYVPLFKWKKR----PPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEH-METFTM-EQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKY 489
             IV+C   +  +   + R    PPGP   P +G++ ++   ++   +  +      SQ YG ++ + LG    V++TG+E I++ S  +    RP+    Y + SF + LG++F DGP W   R+F+++ L+ FG   + M  +I DE +  +Q LR     +A   + +   F++  +N++WRLV G+R+D  D+RL EL    M  F + + + G +  + +L++  P    +  + +      ++L   ++E + +L     +  ID+FL      ++      D Q+V    D    G  T++ T  + +L +V+  +VQ +  +EI D +G      L DR  + + EA+++E  R+S+V  +  P + L D  +G+++I +GT + ++LY LH    HW DP++FRP+RF+  K G +  DEWL PFG GKR+C+GE +A+  + +FL + L KF     K  +   + +P+ GL++  K++
Sbjct:    4 LIVLCFILFFYIISRRHRGLCYPPGPTPLPIVGNLLSV-LWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIREVSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGDECEALVQ-LRLA---DAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKELCSLVMRLFKLVDMSGGFLNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQENLQLGAPKDVIDAFLIDMLESQDDKPTLDDLQVV--CLDLLEAGMETVTNTAVFMLLHVVRNEDVQRKLHQEIDDIIGRDRNPLLDDRIRMVYTEAVILETLRISTVASMGIPHMALNDAKLGNYIIPKGTFILLSLYELHHG-PHWKDPETFRPERFLT-KEGNILQDEWLIPFGIGKRRCIGEGLARSELFMFLTHILQKFHLRIPK-NEPLPSTEPIDGLSLSAKQF 480          

Query:    3 LFLGLFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSM-MDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIE------HMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQAR-GREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKY 489
            L LG    +    ++   + K  PPGPW  PF+G++  L       +E  +  + +  + YG +  + L     VI+TGL  IK+  + MD+      +  + E  SF +  G+I   G LWKEQR+F + TLR FGLGK+++E+ IQ+E +     L E   +            N    N+I  +  G RF+Y D +  EL++      ++E   + Q       I  +K++P   Q      K + +F   +S  ++  K   +    R +ID++L+  ++    A   F+++ L+ S  D F  G+ T S  + + +LFM  YPE+QE+   EI   +G   + ++  R  LP+  A++ EVQR+ ++LP+  PR    D  +  + + +GT V  NL +LH++ E W  PD+F P+ F+  + G  +  E   PF  GKR CLGE +AK  + +F  + + KF F      DE  TL+   G+T+ P K+
Sbjct:   21 LLLGAVAFLFFAYFLKTRRPKNYPPGPWRLPFLGNLFTLD------MEKSHLQLQQFVKKYGNLFCLDLAGKSIVIVTGLPLIKEVLVHMDQNFINRPVPPIRE-RSFKKN-GLIMSSGQLWKEQRRFALMTLRNFGLGKKSLEERIQEEAR----HLTEAMEKEGGQPFDAHFKINNAVSNIICSITFGERFEYHDGQFQELLKLFDEVMYLEASMLCQLYNIFPWI--MKFLPGAHQTLFSNWKKLELF---VSRMLENHKKDWNPAETRDFIDAYLKEMSKYPGSATSSFNEENLICSTLDLFLAGTETTSD-MRWGLLFMALYPEIQEKVHAEIDSVIGQWQQPSMASRESLPYTNAVIHEVQRMGNILPLNVPREVTVDTTLAGYHLPKGTVVLTNLTALHKDPEEWATPDTFNPEHFL--ENGQFKKKEAFIPFSIGKRACLGEQLAKSELFIFFTSLMQKFTFKPP--SDEKLTLNFRMGITLSPVKH 493          

Query:   26 PPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHM-ETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFL-RAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVG-GLTIGPKKY 489
            PPGP   PF+G+   L + D   L     +  +L + YG + ++ LG    V+L G + I++ +++++  A     ++  +    +  GVIF  G  WK  R+F + T+R+FG+GK+++E+ I++E +C ++ L++      N       +F     N+I  +V G RFDY D +   L+  + +TF++  ++       +   +  F   +++I K++    +++ + V++ +A+L     R +ID++L R +         F  Q LVISV   F  G+ T S TL Y+ L M+KYP V E+ +KEI   +GS    TL DR ++P+ +A++ E+QR + + PI  P    KD +   ++I + T+V   L S   +  ++  PDSF P+ F++   GA++ +E   PF  GKR CLGE +A++ + LF    L  F  + S +  E+  L P   G T  P +Y
Sbjct:   32 PPGPRPLPFLGN---LLQMDRRGL---LSSFIQLQEKYGDVFTVHLGPRPVVMLCGTDTIRE-ALVNQAEAFSGRGTVAVLDPIVQGYGVIFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTF----YFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSAILKYFPGAHRQISKNLQEILDYIGHSVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFLD-ANGALKTNEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSLA-SPVAPENIDLIPNNSGATKTPPQY 485          

Query:    3 LFLGLFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQ-FSMMDET-VARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNL--PCLNVIWRLVCGRRFDYGDKRLAELIE------HMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQAR-GREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFS---GSKLGDE---SATLDPVG 480
            L L     + L  ++   + K  PPGPW  P +G +  L          P+ ++ +  + YG ++S+       V++TG+  IK+ F+ M+   + RP   +L   + F++  G+IF  G  WKEQR+F + TLR FGLGK+++E  IQ+E    ++ ++++        +     FN+     N+I  +  G RF+Y D +  E++        +E+  M Q       I  L+Y+P   Q    +  +    K F+S+ ++  +     D  R +ID+FL+  A+   +    F+++ L+ S  D F  G+ T S TL +A+L M  YPEVQE+ + EI   +G   +  L DR  +P+  A++ EVQR+ +++P   PR    D  +    + +GT +  NL +LHR+ + W  PD+F P+ F+  + G  +  E   PF  GKR CLGE +A+  + +F+ + + KF F      KL  +   S T+ PV 
Sbjct:   21 LLLAAVTFLFLADFLKHRRPKNYPPGPWRLPLVGCLFHLDPKQ------PHLSLQQFVKKYGNVLSLDFANIPSVVVTGMPLIKEIFTQMEHNFLNRP--VTLLRKHLFNKN-GLIFSSGQTWKEQRRFALMTLRNFGLGKKSLEQRIQEEAYHLVEAIKDEGG------LPFDPHFNINKAVSNIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRI--LQYLPGSHQT---LFSNWRKLKLFISDIIKNHRRDWDPDEPRDFIDAFLKEMAKYPDKTTTSFNEENLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIGQGRQPNLADRDSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFL--ENGQFKKRESFLPFSMGKRACLGEQLARSELFIFITSLIQKFTFKPPVNEKLSLQFRMSVTISPVS 493          

Query:    3 LFLGLFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQ-FSMMDETVA-RPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGISY----LKYIP-PFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGR-EAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGP 486
            L LG    +    ++   + K  PPGPW  PF+G+   L   + + LE     +    + YG + S+ LG    V++TGL  IK+    MD+    RP       I+  +   G+I   G  WKEQR+F +  LR FGLGK+++E+ IQ+E     Q L E   E            N    N+I  +  G RF+Y D    +L++ ++  T  +A       +     +K++P P   ++    K     K F+S+ + + +   +    R +ID++L+  ++        F ++ L+ S  D F  G+ T S TL +A+L+M  YPE+QE+ + EI   +G   + +   R  +P+  A++ EVQR+ +++P+  PR    D  +  + + +GT +  NL +LHR+   W  PD+F PD F+  + G  +  E   PF  GKR CLGE +A+  + +F  + + KF F      +E  +L    G+TI P
Sbjct:   21 LLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNF-FLVDFEQSHLE-----VQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKN---GLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEA----QHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLFSNWKK----LKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL--ENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPP--NNEKLSLKFRMGITISP 491          

Query:   26 PPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQD---FFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGIS---------YLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFL-RAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDP 478
            PPGP   P +G+   +   D   L    ++  RL + YG + ++ LG    V+L G++ I++ +++D   A      +  +    +  GV+F +G  WK  R+F + T+R+FG+GK+++E+ IQ+E +C ++ LR+        E  +QD   FF+    N+I  +V G+RF Y D    E +  M  F +  A+  I+  S         +LKY P     +++++ ++   K F++  V++ + +L     R +ID++L R      E    F  + L+ +    F  G+ T S TL Y  L M+KYP + ER  KEI   +G     +L DRA++P+ +A++ E+QR   +LPI  P +  KD+    ++I +GT+V   L+S   +  ++  PD F PD F++   GA++ +E   PF  GKR CLGE +A+  + LF    L  F  + S +  E   L P
Sbjct:   31 PPGPRPLPILGNFLQM---DRKGL---LKSFLRLQEKYGDVFTVYLGPRRTVMLCGIDAIRE-ALVDNAEAFSGRGKIAVVEPVFQGYGVVFANGERWKTLRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKT-------EGVLQDPTFFFHSMTANIICSIVFGKRFGYKD---PEFLRLMNLFYVSFAL--ISSFSSQMFELFHSFLKYFP---GTHRQVYNNLQEIKAFIARMVEKHRETLDPSAPRDFIDAYLIRMDKEKAEPSSEFHHRNLIDTALSLFFAGTETTSTTLRYGFLLMLKYPHIAERIYKEIDQVIGPHRLPSLDDRAKMPYTDAVIHEIQRFGDLLPIGVPHMVTKDICFRGYIIPKGTEVFPILHSALNDPHYFEKPDVFNPDHFLD-ANGALKKNEAFIPFSIGKRICLGEGIARMELFLFFTTILQNFSVA-SPMAPEDIDLTP 472          

Query:   24 KRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQ--FSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNF----VQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKF 464
            K PPGP  FP +G+I  +   D +      +++ + S+ YGP+ ++ LG    V+L G E +K+    + +E   R ++  L ++    + LG+ F +   WKE R+F + TLR FG+GK+++ED IQ+E +C ++ LR+    NA+           PC NVI  ++   RFDY D+   E ++ ME+      I     +      P     +  IHK +    +++ NF    V+E +  L  +  R +ID FL    +  E    F+ + LVI+V D F  G+ T S TL Y++L ++K+PEV  R ++EI+  +G      + DR+ +P+ +A++ E+QR   +LP   P    +DV   ++ I +GT +  +L S+  +++ + +P  F P  F++ ++G  +  ++  PF  GKR C+GE +A+  + LFL + L  FK 
Sbjct:   28 KLPPGPTPFPIIGNILQIDAKDIS------KSLTKFSECYGPVFTVYLGMKPTVVLHGYEAVKEALVDLGEEFAGRGSVPILEKV---SKGLGIAFSNAKTWKEMRRFSLMTLRNFGMGKRSIEDRIQEEARCLVEELRKT---NASPCDPTFILGCAPC-NVICSVIFHNRFDYKDE---EFLKLMESLNENVRILSSPWLQVYNNFPALLDYFPGIHKTLLKNADYIKNFIMEKVKEHQKLLDVNNPRDFIDCFLIKMEQ--ENNLEFTLESLVIAVSDLFGAGTETTSTTLRYSLLLLLKHPEVAARVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVTRDVRFRNYFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLD-ESGNFKKSDYFMPFSAGKRMCVGEGLARMELFLFLTSILQNFKL 455          

Query:    1 MWLFLGLFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIE--HMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLR-AQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMA 491
            +WL + +  +I  + +    K    PPGP   P +G+ P   K     L + +     LS  YGP++ + LG+D  VI++G + ++   + +E   RP+    + + +F + LGV+F DG LW+EQR+F ++ LR+ GLGK++ME  I++E    +  LR++CN  +   + + D F++  LN +W ++ G RF   DKRL EL++  H     ++ + G +  + +L++I P    Y ++   +     FL   + + + +++ D+ R  IDSFL   + R ++    F + QLV    D F  GS T S TL +A+L+M+ +P+VQ R   E+   +G   + TL DR  L ++E+++MEVQRL S++P+A     LKD ++  H+I +G  V ++++SLH ++ HWGDP+ FRP+             +W  PFG+GKR+CLGET+A+ ++ LF +  L  F  S    G  + + D   G+T+ P+ + A
Sbjct:    2 VWL-ISIICIILYFIWADTVKPCGYPPGPMWLPVVGNYPWFRKKKLQ-LGYHHLVWASLSTKYGPVVGLRLGRDRIVIVSGYDAVRDVLLREEFDGRPD-GFFFRLRTFGKRLGVVFTDGQLWQEQRRFCLQHLRKLGLGKRSMEVQIEEEAGDLVMTLRKKCNGGST-PLQLHDAFDVCVLNSLWAMLAGHRFALDDKRLMELLDIVHTSFRMIDMSGGLLNQMPFLRFIAPDCSGYNQLLTILHRMWNFLKETITDHRRTINPDYARDLIDSFLEEMELRNKQTDSTFDELQLVALCLDLFMAGSETTSNTLGFAVLYMLLHPDVQCRVHDELDGVVGRNRQPTLQDRPRLCYVESVIMEVQRLVSIVPVAVAHRALKDSILMGHIIPEGATVLVSIWSLHMDRNHWGDPEVFRPEX----XXXXXXXXDWFMPFGFGKRRCLGETLARSSLFLFFSTLLHNFTISVPP-GFPAPSPDGYDGVTLSPRPFYA 486          

Query:    2 WLFLGLFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIE--HMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRA-QARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMATV 493
            WL   + + +CL  +  + K    PPGP   P +G+     +     L + +     L   +GP++   LG+   V+++G +  +   + DE   RP+    + + +F + LGV+F +G LW EQR+F ++ LR+ G+GK +M+  I  E    +  LR++ N  +   + + D F++  LN +W ++ G RF   D+R+ ELI+  H+    ++   G +  + +L++I P    Y R+   +     FL   + E + +LS    R +IDS+L   + R  E    F+D QLV    D F  GS T S TL +A+L+M+ +PEVQ R   E+   +G  ++ TL  R  L ++E+++MEVQR +++ P+      LKD  +  H + +G  V ++++S+H +++HWGDP+ FRP+RF++ K G V  D W  PFG+GKR+CLGE + K  + LF +  L  F  S    G    +L+   GL + P+ + A++
Sbjct:    3 WLITVICVFLCL-IWADVKKPHGYPPGPAWLPVVGNYLWF-QQQKKKLGYYHLVWDSLHAKFGPVVGARLGRTRVVVVSGYKAARHILLSDEFEGRPD-GFFFRLRTFGKQLGVVFAEGHLWYEQRRFCLQHLRKLGMGKHSMQAQIAAEAGDLVTRLRDKSNGGST-PLKLHDAFDVCVLNSLWAMLAGERFALDDRRMMELIDIVHVSFRVIDTCGGLLNQMPFLRFIAPGWSGYTRLLSVLNRLWGFLRETIDEHRKTLSPGCTRDFIDSYLEEMEVRKNETDSTFNDMQLVSLCLDLFMAGSETTSSTLGFAVLYMLHHPEVQRRVHDELDGVVGRSNQPTLQHRPRLCYVESVIMEVQRHANIAPLGIAHRALKDTRVMGHFVPEGATVIVSIWSVHMDRKHWGDPEVFRPERFLDGKGGIVH-DNWFMPFGFGKRRCLGEILGKSGLFLFFSTLLHNFSISVPP-GHRLPSLEGSDGLALSPRPFYASL 491          

Query:   26 PPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQF--SMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENA--NHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTM--EQAIG-PIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMATV 493
            PP  W+   +G IP +GK+ + A    + A  ++S  YG ++ + LG    V+++G +E+K    S   E  A P + +L    S     GV+F  G  WKE R+FM++TL++ G GK   E+ +  E K    FL E+    A  + EV +   FN   LN+IW LV G RFDY   ++A+L+  ++ F +  ++ IG P+  I +L+Y PPF   + +  K M   + F+S  +++ + +L  D  R +ID FL        + E+     L+IS  D F+ GS T  K+L YA+  +V+ P+VQ++ ++E+  A+G +  +T+ D+ +LP+ EA ++E+ R+ +++PI+PPR   K + IG  +I   T +  N +++H + ++W DP SF P RFIN + G    DE +  FG GKR+CLGE++A+    LFL N + +F FS    G  S  L   GG T GP  +   V
Sbjct:   31 PPFHWL---LGHIPLMGKSGSIA----HEAFSKISSSYGDLIRLNLGGKDMVLVSGFDELKSIHSSEFAEDRAVPEIANLIFAGSLKETKGVLFNSGSAWKELRRFMLKTLKDLGFGKTASEETVLAETK----FLMEEIGRMAKTDQEVDLDKVFNKAALNIIWNLVAGERFDYEHAKMAKLLACLDAFMLMGKKVIGQPLGTIPFLRYFPPFRATFLKCCKGMEELRNFISETIKDHEDTLDPDNPRDFIDLFLLDLG----STEHMDKSNLLISALDLFSAGSETTIKSLMYAVALLVRNPDVQKKVQEELDAAIGGKPLLTMSDKIKLPYTEATILEIWRVGNIVPISPPRRTSKPLEIGGSIIPANTMIISNTHTMHMDPKYWEDPQSFNPSRFINSQ-GMFVADEKVLAFGTGKRRCLGESLARMENFLFLTNLVQRFSFSPGDQGPPS--LQAQGGFTNGPVPFKVKV 487          

Query:   10 VICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHM-ETFTMEQAIGPIAG-ISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDE-WLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMA 491
            +I L  ++   +  K PPGP   P  G+     K     L + +     LS+ YG I+ + +G+++ V + G E +K+    ++   RP+    + + +F + LG++F DG  W++QRKF ++ L++FGLG++ ME+ IQ+E +  I+ +R +  +   +E+ M   F+   LNV+W ++ G RF   D+RL +L+E M + F +    G +   +  L++I P +  Y ++ + +    EFL   + E + ++ +   R  ID+FL  Q    +    F+D QL+  + D F  GS T S TL +A+L+M+ YPEVQ + + E+ + +G     T  DR+ L + EA++ME+QR ++V P+      ++D  +  + I + T V  +LYSLH +   W DP +FRP+RF+N   G +  DE +  PFGYGKR+CLGE++AK    LF  + L  FK   S+  +   +L+P+ G+T+ PK Y A
Sbjct:   11 IIVLILFIDTIRPNKFPPGPKWLPICGNFTQY-KKKLKLLGYHHLVWQELSEVYGDIVGLKMGRNLVVTVFGAEGVKEVLTREDFDGRPD-GYFFRLRTFGKRLGIVFSDGQFWQKQRKFSIQHLKKFGLGRKEMEEQIQEETRDLIRVIRSELKKE--NEIYMNTLFDTSVLNVLWAMMAGERFQLDDERLKKLLEIMHDAFRITDISGGMLNQLPLLRFIAPNATGYNKLMEILTRMWEFLEGAIAEHRRTVCSSHARDLIDAFL--QKMDVKNDPSFTDDQLMSLLLDLFMAGSETTSNTLGFAMLYMIVYPEVQAKVQAELDEFVGRNRWPTFADRSRLKYTEAVLMEIQRRTNVPPLGIAHRAIRDTFLLGYKIPEDTIVLTSLYSLHMDPHFWKDPLAFRPERFLN--QGQIVADEKYFAPFGYGKRRCLGESLAKTNYFLFFTSILHNFKIEASE-HEPEPSLEPLDGVTLSPKPYRA 486          

Query:   26 PPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIE--HMETFTMEQAIGPIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKY 489
            PPGP   PF+G+ P   + +     F +  +   ++ YG I  + LG  + V ++G   +K+    DE   RP+   L+ + +F   LG+   DG  WK QRKF M+ LR+FGLG++ ME  + +E +  +  LR +C +     + + + F++  LNV+W L+ G RF   + RLA L+   H     ++   G +  + +L+++ P    YK+ +  +    +FL   + E+K + S    RG ID+FL+     +   + F+++QL+    D    GS T S TL++A+L+M+KYPE+Q++ + E+ + LG     T  DR +LP+ EA++ME+QR+ SV P+A P   ++D  +  + I + T V IN+YS+H + + W +P  F P+RF+N K     PD +  PFG GKR+CLGE++AK ++ LF  + L  F        D +   +   GLT+ PK +
Sbjct:   27 PPGPKWLPFVGNFPTF-QIEKRKFGFCHLVLADFAKTYGEITGLRLGNMLLVSVSGSAAVKEVLTRDEFDGRPD-GFLFRLRTFGERLGIALSDGEFWKGQRKFCMQYLRKFGLGRKDMELIVFEEARELVDCLRSKCAQ----PITINNTFDISVLNVLWALLAGERFSLDNPRLAGLLSIIHDAFRIVDFGGGIVNQLPFLRFVAPEYSGYKQSYAILKRTWQFLEEVIDEQKKTFSVTHSRGLIDAFLQQMTELQGQSDTFTEKQLLSICLDLMMAGSETTSNTLSFAMLYMLKYPEIQKKVQDELDEVLGRNRSPTPQDRLKLPYTEAVIMEIQRICSVAPLAVPHRTMRDTELRGYCIPKDTVVIINIYSVHMDPKFWKNPSQFHPERFLNDKGSLSIPDWYFIPFGQGKRRCLGESLAKTSLFLFFTSILNNFHIKNES-PDCTGHFEIHDGLTLSPKPF 485          

Query:   26 PPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQ-TMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGISYL--KYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGR-EAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPL-KDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMATV 493
            PPGP  FP +G++P L  + A     PY A H L++ +G IM++ +G    V+L+  E ++     +E   R   +SL   Y  ++ LG++F +G  +K+QR+F++R L++ G GKQ +ME  I  E+      LR++  +     V M ++FNL  LNV+W ++ G R+ + D++L  L+EH++      ++G ++ +  +  K  P  +   K++  +  + + FL   +QE+K     + ++ ++D +L+   + + ++   +++ QLV+   D    GS T S +L +AIL+M+ YP+VQ+   KE+   +G+ + ++L  R +LP+ +A++MEV RLS+V P A P   + +D +  D+ I + T V INLYS+H N+EHW DP++FRP+RF++     ++ DE + PFG GKR CLGE++A+ ++ L+    ++ FKF     G  S + +PV G T+ P  Y   V
Sbjct:   27 PPGPMPFPVIGNLPQLALSGAKR---PYAAFHNLAKKHGNIMTLRMGAADVVVLSSYEVMRDVLGKEEWSGRIFEESLKARY-LNQRLGILFLEGEAYKDQRRFLLRHLKDLGFGKQNSMESMISVELHELTSRLRQRMADGRQAVVCMHNYFNLSVLNVLWSMIAGTRYSHDDEKLLALLEHVDMLMKCGSVGNLSSMFPILRKLAPKLTGEEKQLEAY-KLLQNFLRELIQEKKEIEDGNPEKCFLDIYLKEIDKFQGDSTSLYTEDQLVMLCFDMLLAGSETTSNSLCFAILYMMLYPQVQDEVHKELVGVVGTANTISLDYRHKLPYTQAVLMEVLRLSNVSPAAIPHTIMERDAIYKDYKIPKDTIVMINLYSVHMNKEHWIDPEAFRPERFLHNGRRLIK-DEHVIPFGVGKRSCLGESLAQSSLFLYFTTLVMNFKFETVP-GHLSPSEEPVLGFTLSPMPYNTVV 492          

Query:    1 MWLFLGLFIVICLYTYVPLF--------KWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEI-YSFDRPLGVIFPDGPL----------WKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTM--EQAIG-PIAGISYLKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMATVQ 494
            +W  + +  ++CL  +  +         +WK  PPGP + P +G++P +   D      P+   H LS+ +GP++ + LG    VIL   EEIK+ +  ++  +R    +   I + F+    + F   PL          WKE R+F ++TLR+ G GK    + +  E    + F++++ NE       +   F+   LNVIW L+   RF+Y D+ + +LIEH   F       IG P   I +L++ PP+   +  + + +  FKE L   V E K  +  +    YID+FL    +  E G Y  DQ LV    D F  G+ T SKT  + I  M+ YPEVQ++ + E+   +  +  ++  D+ +LP+ EA + E+ R+ ++ P  PPR   K+V   D+ +     V  N Y+LH +++HWGDP  FRP+RF+  + G  + DE L PFG G+R+CLGET+A+    +F AN +L FKF  S +G+   +L+P  G T GP  +   V+
Sbjct:    8 LWNRMIVSFLLCLTAFTLILALYVRKHTEWKNPPPGPRIHPVIGALPTMVSLDP----VPHLGFHSLSKMFGPVVRVLLGLQNMVILGRYEEIKEATFHEDLDSRAYFSTGSLIRFGFNPTSSISFFGTPLQDSGIDQVTQWKELRRFTLKTLRDMGFGKSASAESMVYETTILMDFIKKRRNEETGIVKNIGQIFSCASLNVIWNLIAAGRFNYDDENMFKLIEHTNAFMRLGRDVIGKPFGSIPFLRFFPPYKAKFDSLLEGITHFKESLQETVTERKMKMVAEDPSCYIDAFLDKVLKD-ETGIYTEDQ-LVHICMDMFLAGAETTSKTQEFIIAMMLNYPEVQQKVQDEMDSVMKDKPAISWEDKEKLPYAEATMAEIWRVCNIAPFGPPRTAKKEVQFKDYKLPPNASVFYNTYTLHMDEDHWGDPLQFRPERFV--EGGKFKADEMLFPFGIGRRRCLGETMARMENFIFFANLMLNFKF--SMVGNAPPSLEPQSGFTNGPFPFEVKVE 513          

Query:   21 KWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHME-TFTMEQAIGPIAG-ISYLKYIPP----FSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVG--GLTIGPKKYMATVQ 494
            K K  P GP   P +G++    K    +L F +     LS+ YG ++ + LG+++ V + G + IK+    +E   RP+   L+ + +F + LG++F DG LW++QRKF +  LR FG GK+ M+  I+ E K  I   R+QC++     + MQ  F++  LNV+W ++ G RF   D RL  L+  +  TFT+    G I   +  L++  P    F+ +   I K M     FL   V E K++L +   R  IDSF+    + ++  E F+D+QL+    D    GS T S TLA+AIL+MVKYPE+Q+R + EI +A+G        DR  +P+ EA++MEVQR+++V P+      ++D  +    I + T +   LYS+H +++ W DP++FRP+RFI  +   V P+++  PFGYGKR+CLGE +AK  +  F +  L  F         E   +D +G  G+TI PK Y   + 
Sbjct:   22 KPKNFPNGPSWLPVIGNLNIYKKL-LGSLGFHHLVWCELSKKYGNVVGLKLGRNIVVCVLGPDAIKEVMTREEFDGRPD-GYLFRLRTFGKRLGIVFSDGELWQKQRKFSVNHLRHFGFGKKDMDMKIEVETKDLIDVFRKQCDK----PIEMQTAFDISVLNVLWSMMAGNRFSLDDIRLQTLVNCIHHTFTLLDISGGILNQMPVLRHFAPDKTGFNDVVYGIEKLM----VFLREVVDEHKSTLCSSHSRDLIDSFITKMDQPQKH-ESFTDEQLLSLCLDLLMAGSETTSNTLAFAILYMVKYPEIQKRVQDEIHEAVGVNRWPVYEDRIRMPYTEAVLMEVQRIANVPPLGIAHRAIRDTHLQGRHIPKDTIILPCLYSIHMDKDFWKDPETFRPERFIGEEGKIVIPEKYFAPFGYGKRRCLGEALAKSNLFSFFSAILYNFDIQKDP---EHPEIDMIGRDGVTIAPKPYRVVLH 489          

Query:    7 LFIVICLYTYVPLFKW-------KKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQ--AIGPIAGISYLKYIPPFSQIYKRIHK---HMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAG---EYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQ--PFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMATV 493
            +F ++C    V L  W        KRPPGP   P +G+I  LG    +     Y     +S+ YGPI S+ LG    VI    E IK+    +  V R    SL+   SF + LG+IF  G  WKE R+F +RTLR+FG GK++ME  ++DE+K  +  +   C EN +  VAM+  F++P LNV+W LVC    +  DKRL EL+  ++T       A G +    +L++I  FS +    H    +M + + F     +  +  +  +  R YID FL+     RE G    Y++D+Q + +  D F  G+ T + TL + I +M++ PE+Q + + EI   +G     T  D+AE+P+ EA++ E+QR+S+V+ +   R P +DV +  + I +GT   +NL+S+H ++  WGDP+ FRP+RF++     + P++  +  PFG G+R CLGE +A+ T+  + A  L  F F     GD  A    + G T+ P  Y A V
Sbjct:    2 MFEILCFTFIVVLISWVYTDNFKSKRPPGPLRLPLIGTILQLG---VDKRRPQYETFRSISKKYGPISSIELGLYPGVIFDDFETIKKLLNHELWVDR-FFNSLFAERSFGKALGIIFISGDTWKEMRRFTIRTLRDFGYGKKSMESVLEDEVKDLVAKIDGLCEENGSI-VAMKQVFSMPVLNVLWHLVCSTSSE-DDKRLKELLVLVDTLARATPMAGGILMPFPFLRHI--FSDMTGNSHVRKCNMELQEYFRDVLRRRREEGVYKNDQRDYIDVFLQEIDHHREKGSTPNYYTDEQFISTTIDLFEAGAETTNNTLEFGIYYMLQNPEIQAKVQDEIDLVVGKNRLPTFADKAEMPYTEAVLTEIQRISNVVAMT-VRCPTEDVWVDGYFIAKGTIGFMNLFSVHMDKNFWGDPEKFRPERFLDSDKKLI-PNKLQRVIPFGAGRRVCLGEILARATLFTYFATVLQHFTFQKCD-GDSDAQKPAMIGFTLTPAPYSAKV 494          

Query:    3 LFLGLFIVICLYTYVPLFKWKKRPPGPWVFPFMGSIPALGKADANALEFPYRAMHRLSQGYGPIMSMGLGQDMWVILTGLEEIKQFSMMDETVARPNLKSLYEIYSFDRPLGVIFPDGPLWKEQRKFMMRTLREFGLGKQTMEDHIQDEIKCSIQFLREQCNENANHEVAMQDFFNLPCLNVIWRLVCGRRFDYGDKRLAELIEHMETFTMEQAIGPIAGISY----LKYIPPFSQIYKRIHKHMGIFKEFLSNFVQEEKASLSTDFDRGYIDSFLRAQARGREAGEYFSDQQLVISVQDFFTGGSGTMSKTLAYAILFMVKYPEVQERARKEIQDALGSRDEVTLGDRAELPFIEAIVMEVQRLSSVLPIAPPRVPLKDVMIGDHMITQGTQVQINLYSLHRNQEHWGDPDSFRPDRFINPKTGAVEPDEWLQPFGYGKRKCLGETVAKHTVLLFLANFLLKFKFSGSKLGDESATLDPVGGLTIGPKKYMA 491
            + L  F ++ +Y ++   +     PGP+ +P +G++P + + + + +   + A+   ++ YG I  M  G    V+L+  + + +    DE   RP+   + +I      LG+I  DG LWKE R+F +R LR+FG G+  ME  + DE++  +  L +Q   N    ++ +  F    L+ +W +V   R +  D  +  L   ++     +A G  AGI +    L+++ P    + +  +   I KE +   + E K +      R +ID++L       E   YF D+QLV++  D F  GS T + TL +A+L+++ +PEVQ++ + EI+  +G    V+L D+ +L + EA ++EV R SSV PI  P    + V    + I +G  V IN + +HRN++HWGDPD+FRP+RF++     V  DEWL PFG GKR+C GE +AK +V L ++N L KF FS +  G+   +  PV GL + P  Y A
Sbjct:    2 ILLIFFTILIVYLFMSTRRRPNELPGPFKWPIVGNLPQIAQVNWSRV---WHAVDHYAKIYGEIYGMYFGPRYVVVLSDPKVVHELMKRDEWNGRPH-DHMAKIKGDGAVLGIIMTDGDLWKETRRFSLRHLRDFGYGRSNMETSVMDEVQNVVDRLDKQIG-NEEQVLSFESTFGPAVLSTLWNMVASIRTELDDPDILRLQRIVKETLQRRAFG--AGIFWSFQSLRHLFPQGSGFAQQIEGFNILKENMRKVITEHKKTRVPGEPRDFIDAYLEEHENNPE-NPYFFDEQLVVTCMDLFVAGSDTTTITLRWALLYLILHPEVQKKVQAEIESVVGLDRPVSLADKEKLNYFEAFLLEVNRYSSVAPIVTPHALTETVTYKGYEIPKGALVFINTWGIHRNKDHWGDPDTFRPERFLDKNGKVVTNDEWLLPFGSGKRRCPGEPLAKTSVFLMVSNLLQKFSFS-TVPGEPRPSPIPVIGLNLAPLTYRA 485