Query:    4 RAIVSVHVGHYANHVGSHLWNIQEANF-----AYEGQSETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREA----------------KKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDLTSLLP--GIGQESGSVN-AQSLVMRGLDR----SLLKPADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEG-IYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            R ++++ +GH+A  VG+H WN Q+A       A E   E C D+LYR G TL+ Q T+TPR+I +D +G+L +L Q G LY    +   A + W G     KEE   KNP+  +L S       D    GT R ++                K     +  +R WSD+L    HP+S  ++  Y H       + F  G    KE    EE+EDR+ F+VE+ D +QGF IL D  DGF G+ A   + L+DE+  +  + +   P  Y          RLLN+   L      SS + PL+L     + P      P +QY   L +H  AI+A+ LD++T+P+R    P  +  + + LN  G+K+  A A  PF   P + L D L +  + T   P    G  SG+   AQS+V+RGLDR    S L P         +  P     + EE L QYL +Q  R  S  H   T   V  PYP LF + LS  G +    P   +  + S+P L    SS      L  +   ++K+++ +   F  +G E   LEE+++ + +L + Y+
Sbjct:    6 REVLTLQLGHFAGFVGAHWWNQQDAALCRPTDAKEPPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLSSLKQEGGLYRDKQLD--AAIAWQGKLTTHKEELYPKNPYLQDLLSAEGVLSSD----GTWRVKSIPNGKGLPPFTNAITPKPVMPTEGSIRVWSDFLRVHLHPRSICMIHKYNHDGEAGRLEAFGQGESILKEPKYLEELEDRLHFYVEECDYLQGFQILCDLHDGFSGLGAKAAELLQDEYSGRGIITWGLLPGPYRLGELQKNIYRLLNTAFGLVHLSAHSSLVCPLSLGGSLGLRPEPPVSFPLLQYDATLPFHCGAILATALDTVTVPYRLRSSPVSMVHLADMLNFSGKKVVTAGATIPFPSVPSQSLPDTLMQLGEATPWTPLSACGDPSGTCCFAQSVVLRGLDRAHHTSQLAPG------TPLPSPLHACATGEEVLAQYLQQQQPRVRSSSHLLLTPCKVVPPYPSLFSSSLSQHGSVLDGLPTGTA--VESIPVLGALCSSSSLNRALGDLAKDLSKLDLRRWASFMDAGVEQDDLEETLQDLRSLAQCYE 564          

Query:    4 RAIVSVHVGHYANHVGSHLWNIQEANFAYEGQ---SETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNA------------SEKDLCEV----------GTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKEDVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDLT-----SLLPGIGQESGSVNAQSLVMRGLDR----SLLKPADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYR--QTPRNAS-DKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLH-RFETSGCEASVLEESMEKVLALKENYQ 546
            R +V++ +GHY+N +G+H WN+Q+A   Y+      E   D+L+REGLTL   VT+TPR+I +D +G+L  L + G LY+  T  + +   W G  +  +E P  KN F  ELD+L+              S  D C V           +S    +K Y L+  VR WSD+L    HP++  ++  Y H    +  +VF  G    +  V E++EDR+ FF+E+ D +QGF +L D  DGF G+ + + +YL+D +G +  L +  +P  +P+ S +     ++N  L        SS   PLTL       P      P +   P L YHSS+++A  LD+LT+ +R       ++ + + L   GRK+ +A    PF +  G  L D L    +       S  P I        +QS+ ++G+D     S L P       M    P    +S E+ L  Y+   Y   P  V    +G+ V+ P+P +F   LS +G  +   TP + S   ++ +P L + QSS      L  +    A +++ ++   F T G E + + E +E++  L   Y+
Sbjct:    6 REVVTLQLGHYSNFIGTHWWNLQDAGLVYDADVPAGELQSDVLFREGLTLAGHVTYTPRLIAIDLKGSLQTLRKEGSLYD--TENENSAFTWDGQIMTHQESPPSKNSFLQELDNLDTGGVLAESDFNHLTSSVDNCSVPGASVAVETINSSLERIQKSYRLEGSVRVWSDFLRLHLHPRTISVINQYNHDGESERLEVFGQGEALLQGQVLEDLEDRLHFFIEECDYLQGFQVLCDLTDGFSGLGSKVTEYLQDSYGGRGILTWGVAPVNHPDTSSMKDLYHMMNCALGTLQMANHSSLFCPLTLRGGLCRRPPPPTAFPLLNCDPLLWYHSSSVLALALDALTVSYRMRHCSATMWQLSDALTTSGRKVVSAYGSVPFPMMLGGCLPDALDAFSNAVPWRSLSACPEISDRRFCF-SQSVTLKGVDEQSLVSRLLPG------MEAPSPLHYERSGEDVLSAYVRSHYPSSPLAVQLVSSGSKVTPPFPQIFSPSLSAQGFLQSHSTPASPSCPPVSCLPVLTSLQSSPAVGLQLSELQRACASLDLRRVAPSFLTHGPEHAEISEYLEQLRNLAHCYR 577          

Query:    4 RAIVSVHVGHYANHVGSHLWNIQEANF-----AYEGQSETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKD-LCEVG-----------TSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDLTSLLP--GIGQESGS-VNAQSLVMRGLDRSLLKPADFERNQMFVNHP----FLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            R ++++ +GH+A  VG+H WN Q+A       A E   E C D+LYR G TL+ Q T TPR+I +D +G+L +L + G LY    +   A + W G     KEE   KNP+  +  S       D +  V            T+    K     +  +R WSD+L    HP+S  +++ Y H       + F  G    KE    EE+EDR+ F+VE+ D +QGF IL D  DGF G+ A   + L+DE+  +  + +   P  Y          RLLN+   L      SS + PL+L     + P      P + Y   L +H SAI+A+ LD++T+P+R    P  +  + + L+  G+K+  A A  PF L PG+ L D L +    T   P    G+ SG+   AQS+V+RG+DR+         +Q+    P         + EE L QYL +Q  R  S  H   T   V+ PYP LF +      +   +P+ A +   S+P      SS    + L+ +   + K+++ +   F  +G E   + E ++++ +L + Y 
Sbjct:    6 REVLTLQLGHFAGFVGAHWWNQQDAALGRATDAKESPGELCPDVLYRTGRTLHGQDTCTPRLILMDLKGSLSSLKEEGGLYRDKQLD--AAIAWQGKLTTHKEELCPKNPYLQDFLSTEGVLSSDGVWRVKSIPNGKGSPPLTTATTPKPLIPTEASIRVWSDFLRVHLHPRSICMIQKYNHDGEAGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKAAELLQDEYSGRGIITWGLLPGPYHRGEAQRNIYRLLNTAFGLVHLTAHSSLVCPLSLGGSLGLRPEPPVNFPYLHYDATLPFHCSAILATALDTVTVPYRLCSSPVSMVHLADMLSFCGKKVVTAGATIPFPLAPGQSLPDSLMQFGGATPWTPLSACGEPSGTRCFAQSVVLRGIDRAC------HTSQLTPGTPPPSSLHACTTGEEVLAQYLQQQQPRVMSSSHLLLTPYRVAPPYPHLFSSCSPQGMVLDGSPKGAVE---SIPVFGALCSSSSLHQTLEALARDLTKLDLRRWASFMDAGVEHDDVAELLQELQSLAQCYH 562          

Query:    4 RAIVSVHVGHYANHVGSHLWNIQEANF-----AYEGQSETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSL------------DEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDLTSLLP--GIGQESGS-VNAQSLVMRGLDRSLLKPADFERNQMFVNHP----FLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            R ++++ +GH+A  VG+H WN Q+A       + E   E C D+LYR G TL+ Q T+TPR+I +D +G+L +L + G LY    +   A + W G     KEE   KNP+  +  S       D      S    K    L            +  +R WSD+L    HP+S  +++ Y H       + F  G    KE    EE+EDR+ F+VE+ D +QGF IL D  DGF G+ A   + L+DE+  +  + +   P  Y          RLLN+   L      SS + PL+L     + P      P + Y   L +H SAI+A+ LD++T+P+R    P  +  + + L+  G+K+  A A  PF L PG+ L D L +    T   P    G+ SG+   AQS+V+RG+DR+         +Q+    P         + EE L QYL +Q     S  H   T   V+ PYP LF +      +   +P+ A+  + S+P      SS    + L+ +   + K+++ +   F  +G E   + E ++++ +L + YQ
Sbjct:    6 REVLTLQLGHFAGFVGAHWWNQQDAALGRATDSKEPPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLSSLKEEGGLYRDKQLD--AAIAWQGKLTTHKEELYPKNPYLQDFLSAEGVLSSDGVWRVKSIPNGKGSSPLPTATTPKPLIPTEASIRVWSDFLRVHLHPRSICMIQKYNHDGEAGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKAAELLQDEYSGRGIITWGLLPGPYHRGEAQRNIYRLLNTAFGLVHLTAHSSLVCPLSLGGSLGLRPEPPVSFPYLHYDATLPFHCSAILATALDTVTVPYRLCSSPVSMVHLADMLSFCGKKVVTAGAIIPFPLAPGQSLPDSLMQFGGATPWTPLSACGEPSGTRCFAQSVVLRGIDRAC------HTSQLTPGTPPPSALHACTTGEEILAQYLQQQQPGVMSSSHLLLTPCRVAPPYPHLFSSCSPPGMVLDGSPKGAA--VESIPVFGALCSSSSLHQTLEALARDLTKLDLRRWASFMDAGVEHDDVAELLQELQSLAQCYQ 563          

Query:    4 RAIVSVHVGHYANHVGSHLWNIQEANFAYEGQS-----ETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSL------------DEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDLTSLLP--GIGQESGS-VNAQSLVMRGLDRSLLKPADFERNQMFVNHP----FLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            R ++++ +GH+A  VG+H WN Q+A       S     E C D+LYR G TL+ Q T+TPR+I +D +G+L +L + G LY    +   A + W G     KEE   KNP+  +  S       D      S    K    L            +  +R WSD+L    HP+S  +++ Y H       + F  G    KE    EE+EDR+ F+VE+ D +QGF IL D  DGF G+ A   + L+DE+  +  + +   P  Y          RLLN+   L      SS + PL+L     + P      P + Y   L +H SAI+A+ LD++T+P+R    P  +  + + L+  G+K+  A A  PF L PG+ L D L +    T   P    G+ SG+   AQS+V+RG+DR+         +Q+    P         + EE L QYL +Q     S      T   V+ PYP LF +      +   +P+ A+  + S+P      SS    + L+ +   + K+++ +   F  +G E   + E ++++ +L + YQ
Sbjct:    6 REVLTLQLGHFAGFVGAHWWNQQDAALGQATDSKEPLGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLSSLKEEGGLYRDKQLD--AAIAWQGKLTTHKEELYPKNPYLQDFLSAEGVLSSDGVWRVKSIPNGKGSPPLTTATTPKPLIPTEASIRVWSDFLRVHLHPRSICMIQKYNHDGEAGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKAAELLQDEYSGRGIITWGLLPGPYHRGEAQRNIYRLLNTAFGLVHLTAHSSLVCPLSLGGSLGLRPEPPVNFPYLHYDATLPFHCSAILATALDTVTVPYRLCSSPVSMVHLADMLSFCGKKVVTAGAIIPFPLAPGQSLPDSLMQFGGATPWTPLSACGEPSGTRCFAQSVVLRGIDRAC------HTSQLTPGTPPPSALHACTTGEEVLAQYLQQQQPGVMSSSRLLLTPCRVAPPYPHLFSSCGPPGMVLDGSPKGAA--VESIPVFGALCSSSSLHQTLEALARDLTKLDLRRWASFMDAGVEHDDIAELLQELQSLAQCYQ 563          

Query:    4 RAIVSVHVGHYANHVGSHLWNIQEANFAY-----EGQSETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEE--VRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDLT--SLLPGIGQESGS-VNAQSLVMRGLDR----SLLKPADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGI-YRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            R ++++ +GH+A  VG+H WN Q+A         E   E C D+LYR G TL+ Q T+TPR+I +D +G+L  L + G+LY    +   A + W G     +E+   KNP    L S       D    G  R +  ++    +E  ++ WSD+L    HP+S  ++  Y H       + F  G    KE    EE+EDR+ F+VE+ D +QGF +L D  DGF G+ A   + L+DE+  +  L +   P  Y          RLLN+   L      SS + PL+L  +  + P      PS+ Y   L +H SAI+A+ LD++T+P+R       +  + + L+  G+K+  A+A  PF L  G+ L D+L +  + T  + L   G  +G    AQS+V+RG+DR    S L P     + +          S EE L QYL +Q+ R  S  H   T   V+ PYP  F +  S +G+    TP+ A+  + S+P     +S+      L  + + ++++++ +   F  +G E   +EE + ++  L + YQ
Sbjct:    6 REVLTLQLGHFAGFVGAHWWNQQDAALGRMAEDEESPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLNTLKEEGNLYRDRQLE--AAVAWQGKLSTHREDAHPKNPNLQGLLSAEGVRSSD----GAWRAKLIQNIQNGKENSIKVWSDFLRVHLHPRSICVIHKYHHDGETGRLEAFGQGESVLKEPRYLEELEDRLHFYVEECDYLQGFQLLCDLHDGFSGVGAKTAELLQDEYAGRGVLTWGLLPGPYSLGEPQKNIYRLLNTAFGLVHLTGYSSFVCPLSLGGNLGLRPKPPVNFPSLHYDATLPFHCSAILATALDTVTVPYRLRSSMVTMAHLADVLSFSGKKVVTAEAIIPFPLVRGQSLPDILTQLGEATPWTSLSACGDSAGHRCFAQSVVLRGIDRASHTSKLNPGTPLPSALHA------CASGEEVLAQYLQQQHPRVLSSSHLLLTPCKVAPPYPHFFSS-FSQKGLAMDSTPKGAA--VQSIPVFGALRSTSSLHRTLGDLAEELSRLDLRRWASFMDAGVEQDDMEEMLHELHRLAQCYQ 549          

Query:    4 RAIVSVHVGHYANHVGSHLWNIQEANFAYEGQSETC-------HDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGL-LWTGATVVQ----KEEPLKKNPFQLELDSLNNAS----EKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPP---AYPEYSGILG-STRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPN-GHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQD---LTSLLPGIGQESGSVNAQSLVMRGLDRSLLK-PADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYP-DLFDARLSNEGIYR---QTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENY 545
            R I++   G YAN+VG+H WN QEANF Y  +SE         +DILYREG     + T+TPR+++VD  G LG LP  G+LY          L L TG  + Q     EE    +P QLE+   + AS    ++DL +        +K+Y L     +W D+LY R+HP++  +L       T +    ++ G E W+E    EE  DRIR +VE+ D +QGFH+L D  DGFGG+    +++L DE+ ++     P   P   +YP+    L  S R++N++L      E +   TPL+  +  +   N   R LP +Q++ + +Y +SA++A+  D+ TL +R  + P  +      +   GRK+ AA    PF L  G+ L++ L +  D   LT L PG  +   S   QS+  RG+    LK P +   +Q+ +        SI   L+ Y    Y    +             P+P ++F A +S +G YR      R    ++ S P L   Q+S    E+L  +  +  ++ + KL  +  SG E    + +++++L  ++ Y
Sbjct:    5 REILTFQFGTYANYVGTHFWNQQEANFRYGDESEQVAEEQLPNNDILYREGRNDLNRTTYTPRLLSVDLSGTLGHLPVTGELYGNFVQRDEELLPLSTGEELEQVRKRAEESGVCSPEQLEVQEQSKASISEYQRDLLKNAVV---PEKNYQLAATANSWVDFLYARYHPRTLNVLPGLIRDPTAQALGTYSAGTEMWQEVSFNEEFCDRIRLYVEECDGLQGFHVLFDIDDGFGGLAGKCLEHLNDEY-SRASFALPLHYPRITSYPQADTRLSHSIRVVNNVLGYHQLSEQALMFTPLSTLETIWRNNNLKSRSLPGLQWETDNLYQTSALLAAFFDTATLSYRLRQTPESLLRFCECVTPAGRKMTAAGLALPFGLREGQDLIEFLDQSGDHALLTQLTPGC-EPGTSYVVQSVTARGIPAERLKRPRELAGDQLRM--AAYSCDSISHMLQLYYQCTYHGSVTNAAATPLPLKTQLPFPYEMFAAGISRDG-YRLPEGAERETGSRVDSAPMLAAVQNSTKLGEHLDNVHAQSHRVQLAKLQAYSNSGLERDEYDTALDQLLEFRDLY 568          

Query:    6 IVSVHVGHYANHVGSHLWNIQEANFAYEGQSET--CHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDR-IRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWR 327
            IV++ +G  AN++ +H WN+QE+ F Y G+ E+   HD+ +R G+  +   TFTPR +  D +GA G L ++  LYE      +   LW G  V+Q++ P+ ++ +Q  LD+   A +                    E VR WSDY    +HP+S V L DY+  + + PF+ +++G + + + D   ++ DR +R F E+ D ++   + T   D +GG +A  VD L DEFG K+  V+     +       L   R +N   ++ S    SS  TP+       + P  H  L  + + P+  +H++A+++S ++S+TLP R
Sbjct:    4 IVTLQLGQRANYLATHFWNLQESYFTYNGEEESPVDHDVHFRPGVGADGTETFTPRTVIYDLKGAFGTLRKYNALYELTEDANLGQGLWDGKEVIQQQTPISQSDYQKNLDAGLPAPKL-----------------TTETVRYWSDYNRLFYHPRSIVQLNDYELNSMIMPFEDWSVGEDLFSDLDKEHDLLDRDVRPFAEECDQLRAIQLFTSSDDAWGGFSARYVDRLRDEFGKKSIWVWAIEGGSRVSRQTQL--KRDMNKARTIYSISPQSSLYTPI-------IDPPSH-TLSKVHFDPHSEWHTTALISSAMESVTLPTR 302          

Query:    6 IVSVHVGHYANHVGSHLWNIQEANFAYEGQSETC--HDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDR-IRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLL---NSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTR--IYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDL 376
            I+++ +G  +N++ +H WN QE+ F Y    E    HDI +R G+  +   T+ PR +  D +G  G++ +   LY  L   +    LW G TV+QK+  + ++ +Q  LD+     E       T              VR WSD+    +HP+S V L +Y+  +++ PF+ +  G + +   D   ++ DR +R F+E+AD +QG  ++T   D +GG  A  ++ + DE+G     V+ +   +     G+    RLL   N   +++   + +S + P T+      LP       S+       +H++A+ A+ ++S+TLP R  +   R  +  + + LN  G++  A+     F   P E    V++  QD 
Sbjct:    4 IITLQLGQQSNYLATHFWNAQESYFTYSEDQEPAVNHDIHWRPGIGADGTETYMPRTVIYDLKGGFGSMAKTNALYNDLEEGQTPQALWNGPTVLQKQPAIPQSAYQQSLDA---GLEPPPLTTDT--------------VRYWSDFNRVFYHPRSVVQLNEYELNSSIMPFERYATGEDLFASLDKEHDLLDRDLRPFIEEADQMQGIQVMTGLDDAWGGFAAKYLERIRDEYGKTAMFVWGSEQESVMRAGGLSREKRLLRLANKARTMTEVYKYASVVVPFTVPA---TLPG------SVVLDAGSQWHNTALSAAAIESVTLPSRLRDPANRDTMATLADSLNAMGKQNVASLG-MSFAPEPTEEEDVVMEGTQDF 356          

Query:    6 IVSVHVGHYANHVGSHLWNIQEANFAY-EGQ-SETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDR-IRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPS-IQYKPNLMYHSSAIVASVLDSLTLPWR 327
            I+++ +G  AN++ +H WN+QE+ F Y EG+ S   HD+ +R G+  +   T+TPR +  D +GA G L +   LYE  T  +    LW G  V+QK+ P+  + +QL L       E+ L     S           E VR WSDY    +HP+S + L DY+  + + PF+ +++G + + + D   ++ DR +R F E+ D ++ F +     D +GG  A  +D + DE+G K   V+     +  +    L   R +N   S+ +    SS   P+   KD    P GH  +PS I       + +SA+++S L+++TLP R
Sbjct:    4 IITLQLGQRANYLATHFWNLQESYFTYNEGEESPIDHDVHFRAGVGADGSETYTPRTLIYDLKGAFGTLRKQNALYELSTDSEYGQGLWDGKEVIQKQTPIIPSEYQLNL-------EQGLPAPALS----------SETVRYWSDYNRVFYHPRSIIQLNDYELNSKIMPFEDWDVGEDLFNDLDKEHDLLDRDVRPFAEECDQLRAFQLFAGSDDAWGGFAAKYLDRIRDEYGKKAVWVWAMEGGSKLQRRNQL--KRDINKARSIHAMAPQSSLYVPI---KD----PPGH--VPSTINLDAQSEWQTSALISSALETVTLPTR 302          

Query:    5 AIVSVHVGHYANHVGSHLWNIQEANFAYEGQSET---C--HDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLEL---DSLNNASEKDLCEVGTSRREAKKD----YSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAW---KEDVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDLTSLLPGIGQESGSVNAQSLVMRGLDRSLLKPADFERNQMFVNHPFLGSKSIEEALEQYLAEQYER-CPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            +I+++  G+YAN+VGSH WN+QE+ F YE   +    C  +D+LYREG TL++Q T+TPR++ +D +G+LG LP+ GDLY   ++PK++ L W G   + KEEP + N F  EL   +  N+  E+D  E+ T + ++K+     Y+LD++V  WSDYLY R+HPKS +++  +QH+NT  PFD+F LG + W    +DVG E+EDRIRFF E++D+++GFH+L D   GFGG+   + D L D++ +K+ L  P  PP   +Y+     + L ++ L+L+  ++ +   TPL+L  D F L   +     +++   L YHSS+I+A+ LD+ TL +R  EK   I DV++GL+   + +    +  PF L   E +     +K  L+ L P I   S + + +S       R +LK A F+      N    G  + +E LE  + EQ  R C   +  F       +P+P +FD R+S +G      R+ +D ++ VP L +W +       L  +  +  K+NI +L R    G E     E++E +  + E Y 
Sbjct:    2 SIITLQCGNYANYVGSHFWNLQESGFEYETNKQVGPDCVDNDVLYREGFTLDKQSTYTPRLVAIDLKGSLGTLPELGDLYHKPSIPKLSTLNWYGKGEILKEEPPRLNQFLQELRETEQENSEKEEDDEEILTVKTKSKQIKSAVYNLDKDVHYWSDYLYARYHPKSVLVVESFQHENTTHPFDIFGLGHQLWIDQHQDVGSEVEDRIRFFAEESDNLKGFHLLADSQSGFGGLAGRITDLLTDDYSSKSTLNIPVIPPTLGKYTFHTCGSALASNTLTLARFLD-NGLTTPLSLLSDWFPLQGRNMSFEFLKFNAELHYHSSSILATALDTSTLVYRKKEKSASIADVISGLSQGHQNLAVISSSLPFNLTGIESI-----EKDLLSELTPLIPASSPTHSNRSYPALLTLRGILKSAIFKNRSSKYN----GISTPDEYLEYCVREQSSRSCIPRICAFSKPIRTCKPFPHIFDPRVSVDGNILGKQRSENDGVSCVPLLNSWNTGPSAAASLANLSSKCGKLNISRLPRMLECGTEEVDWREAVETINTMAERYH 549          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAYEG-----QSETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDS-----------LNNASEK-DLCEVGTSRREAK-------------KDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIY--DVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQK-KQDL--TSLLPGIGQESGSVNA--QSLVMRGLDRSLLK-PADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQPPSCM 551
            MS R +V++ +GHY+N+VGSH WNIQE++F Y+      Q +  HD+L+REG  L  +VT+TPR++  D +G+L  L Q G LY+     ++    WTG   + +E+   KNP+ L+L+             NN+ E  D  E+  S  E K             K Y LD+ V  WSDYL    HPKS  ++  Y+HKN L+PFD++  G E   + +   E+EDR+ FF+E+ D +QGFH+L D FDGFGG+ + ++ +LEDE+ +K    F  +P   P+ +    + R+LNS +S S     SS   P+ LA   +       +L  +QYK +L YH+SAI+A+ LDS+T P+R   +P  ++  D+ +     GRK+ +    FP+ ++  ++LVD L     DL   SL P +     +VN   QS V+RG+  ++ K     ER+     H F   +++++ L+ YL +++    S     +    V  PYP +FD  +S  G    T R     + SVP + + QS+ D  E L+ +    +K+NIHK HR+  +G E     E +     L+  Y+ P  M
Sbjct:    1 MSSREVVTLQIGHYSNYVGSHWWNIQESSFIYDPKLAPVQKDIDHDVLFREGKNLRGEVTYTPRLVAFDLKGSLNTLKQEGSLYDHRHQEEIR---WTGDVTLHQEDGADKNPYLLDLEKEEQLYMKDNTGSNNSQESIDDVEIKDSGSEVKERKQKSSDAGIRNKFYKLDDSVTVWSDYLRTFLHPKSIHVIEKYRHKNDLQPFDIYGCGQEVMADYETRIEVEDRLHFFIEECDHLQGFHVLLDTFDGFGGLGSHVLQHLEDEYSSKGIFTFGLTPNNLPDDTPQKRANRILNSAISYSKCWSNSSLFVPMCLANSLWKTIGPPVQLSHLQYK-SLDYHTSAILAATLDSVTSPYR---QPAVLHMRDLTDTFQSIGRKMASVSTSFPYPIHEDQFLVDSLMSIGNDLPWVSLTPHV---KNTVNPFLQSTVVRGISNNIAKRSVQDERSP----HQFRTCQTVDDVLQMYLRDRFPTTHSDGTVLRDPCKVVSPYPHIFDPNVSKNGFLSSTKRADFQGVESVPVMTSLQSTSDTVELLQTLHTEASKLNIHKHHRYLAAGIEEDDYVEILANFETLQHCYEEPGDM 576          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAYEGQ--SETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLK-KNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKEDVGEE-IEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPE----------YSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQD--LTSLLP--GIGQESGSVNAQSLVMRGLDRSLLK--PADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            M  + I+++  GHYAN VG+H WNIQE++F Y+    SE  H++L+REG+T   QVTFTPR++ VD + +L  LP  GDLYE L  P    + W G  +  +E P + KN FQ ++   NNAS   L  V T      K Y+L+++V+ WSD+LY RFHP++  +++ YQH N   PFD ++LG   WK +V E+   D IR +VE+ D  QGFHILTD  +GF G+++  ++++ DE+  K+ LV PT P  +P+          YS +  STR++N +LS ++  E SS   PL  ++  +  P   R+    QY   L YHSSA +A+ LD+++L +R       + D+   L    RK  A     PF LN    L+D L + +     S+ P   IG E      Q L++RG+  + LK  P    + +    +     KS+++ LE +LA       S V T     S   P+PDLFD R+   G     PR    ++ SVP L    S  +  +  + +     K+ I + ++F     EA   E+++  V+ L+ENY+
Sbjct:    1 MVSKEILTLQFGHYANFVGTHWWNIQESSFQYDSAAPSEIDHNVLFREGITPAGQVTFTPRLLLVDLKNSLKTLPIQGDLYEELPDPSQLFMKWEGHKIELQEAPRESKNAFQTDI---NNASA--LPTVAT------KKYNLEQDVQVWSDFLYSRFHPRTVNVIKQYQHCNAETPFDSYSLGAALWKSEVFEDRFSDDIRRYVEECDHFQGFHILTDCTNGFAGLSSACLEHIRDEYDRKSVLVLPTIPAHFPDNDFQTAHEQVYSLMNDSTRVINLLLSFNTYREFSSMFVPLCTSEAGWRQPGLPRQFHHTQYNHKLPYHSSAFLAAALDTISLKYRLESSTFSLSDLCADLTANDRKAAAGSLCMPFSLNADADLIDCLDQWEGPLYKSITPRCSIGTERV---MQHLMLRGVPETRLKKPPNKAGKQKAMAAY---NCKSVKDMLELFLACSTYATASHVSTISEAMSTKNPFPDLFDDRIGVHGNVSAIPRLEHTRVESVPILAGLHSGSEIGQMFESLHTEAKKLKIARFNQF---TLEADEYEDALNSVMTLRENYE 546          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAYEGQ--SETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLK-KNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYP--EY--------SGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQD--LTSLLPGIGQESGSVNAQSLVMRGL-DRSLLKPADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            M  + I+++  GHY+N VG+H WNIQE  F Y     SE  HD+LYREGL+   +VTFTPR++ VD +G+L  LP+ G+LYE L  P    + W    V  +  P + KN FQ +L+       + L  V      +K+ Y  D++ R WSD+LY RFHP++  ++++YQH N   PFD F LG   WK     E+  D+IR ++E+ D  QGFH+LTD  + FGG+T+  +++L+D++G K+ LVFP  P  +P  EY        S I+ S R+LN  LS +   E SS L PL++    +  P   R+  ++ Y P L YHSSA++A+ L++ ++ +R       + D+   LN  GRK+ AA    PF L  G  L++ L K +     S+ P     +  V  Q + +RG+ +  L KP +  + Q  +  P     SIEE L  +L+   E   S V        V  P+P +F+  +   G   +  R     +  VP L    +  +  + L+ +     KI + + H+F + G +    EE ++ + AL+ENY+
Sbjct:    1 MVGKEILTLQFGHYSNFVGTHWWNIQEQGFEYNSNIPSEINHDVLYREGLSPRGEVTFTPRLLLVDLKGSLKTLPEIGELYERLPHPSEVKVEWDENLVETRPGPSEVKNKFQADLED-----PEKLQSV------SKESYDFDKDARVWSDFLYTRFHPRTVNIVKEYQHCNENTPFDAFPLGASLWKTPQFEEDFSDKIRNYIEECDGFQGFHVLTDCTNAFGGLTSSCMEHLQDDYGRKSILVFPVIPSHFPDNEYQTEEEKLQSVIIDSVRMLNVALSFNEFTENSSLLVPLSVGSTGWRQPGLKREFRNVVYDPKLPYHSSALLATALETFSMKYRLKSSGFALADLSADLNQGGRKVAAASLCLPFPLKEGGDLLECLDKWEGPLFQSITPNCTIGNYRV-MQHVALRGIAEERLKKPLNQAQKQREL--PAYRCDSIEEMLTLFLSYTSEATASNVTVVHKPLDVRNPFPRIFNRNIGQNGCVSEFERADGIGVEKVPVLSGLHTGSEVGQMLENLHTEARKIKVARFHQFASEGIQKDDFEECLDNLFALRENYE 549          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAYEGQ------SETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDS-LNNASEKDLCEV-------GTSRRE------AKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDV---LQKKQDLTSLLPGIGQESGSVNAQSLVMRGLDRSLLKPADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            MS + I+++ +GHY+N VG+H WN+QE++F Y+ +       E  HD+L+REG T+   VT+TPR+I  D + +LG L + G LY+   V     + W G   + K + LKKN F   LD  L   +E    +        GT+  +       K  Y+LD  V  WSDYL   FHP+S  +L+D+ H NT  PF+VF +G +     +  +EIE+R+RFF E+ D +QGFHIL D    FGG+ + ++ YL +EF +K+RL F  +P    + + +  S R+LNS LSL+   E S    PL+LA   +      R LP +QY+  L YHSS+I+A+ LD+ TLP+R  +   ++ ++ +  N  GRK+ A  +  PF L  G  +VD    L+K Q  +S+ P +   S  ++    V RGL  +++     + +     H F    SI++ +  Y +E +    S     +    V  P+P +FD  +++ G    T R A   + +VP + + QS+ D   Y+  +   V+K NI K   F  +G E     E +  + +L + Y+
Sbjct:    1 MSSQEIITLQIGHYSNFVGTHWWNLQESSFVYDPKLLEGSPKEIDHDVLFREGKTIKGDVTYTPRLILFDLKNSLGTLKKDGTLYD---VESEESVNWVGDVTLHKTQSLKKNKFLQNLDEELVKKNEDIDSDDIDSDQKEGTASYKIIDPVFGKTHYNLDNVVEVWSDYLRTSFHPRSVFILKDHLHNNTESPFNVFGMGQQVCNNGEEWDEIENRLRFFSEECDYLQGFHILLDSHSAFGGLASSILSYLSEEFSSKSRLSFALTPACSSDGTALERSCRILNSALSLNFCSEHSDLYVPLSLASSLWKSVGSPRMLPHLQYQATLDYHSSSILAASLDTATLPYRKEKSGVKMSNITSAFNALGRKVSALYSSLPFPLRSGASIVDTLMELEKTQPWSSMTPHVNSSSPWLDM--CVARGLPTTMINKESHKGDS--AKH-FTRCTSIDDVIRIYCSEVFPSSQSASFVLRDSVKVGLPFPHIFDPHINHCGFITDTLRPALSGVETVPIMTSLQSNPDVFSYIDSLESCVSKFNIAKHQHFIEAGLEPDDFTEMLYNLKSLAQCYK 562          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAY----EGQSETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKED-VGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYS----------GILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQD--LTSLLPGIGQESGSVNAQSLVMRGLDRSLL-KPADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENY 545
            M+ R I+++  GHY+N VGSH WN+QE  F Y    +  SE  HD+ YREG T  R+VT+TPR++  D +G+L +LPQ G LY+P   P      W     +++EE + KN +Q E+D+                 E K +Y+L++ V  WSD+LY RFHP++  ++ +YQH++   PF++F +G + W+ D   E+  D+IR  VE+ D+ QGF IL D  D FGG+    ++Y+ DE+ NK+    P  P  Y +YS          G+    RL+N  L  +  +E SS   PL+ +   +   +  R    + YKP   YHSSAI+AS LD+ TL +R       + D    L  YGRK  AA    PF LN G YL+D L   +     S+ P     S  +  Q   +RG+  + L KP+     Q+  + P     +I+E L  YLA       S V +   G  V +P+PD+FD R+   G      RN    + SVP +    S  +    ++ +   +  I I +  ++ ++G E     E + K+   +E Y
Sbjct:    1 MNTREILTLQFGHYSNFVGSHWWNVQELGFEYNTNTDNPSEINHDVFYREGQTNKREVTYTPRLLLTDLKGSLKSLPQQGYLYDPPVDPNKFETCWHSEVAIEEEEKIAKNEYQKEIDN---------------PAEPKIEYNLEDSVDVWSDFLYARFHPRTVNVINEYQHESEETPFNIFPVGQKLWETDYFKEDYADKIRSNVEECDNFQGFQILLDANDAFGGLAMSCMEYICDEYENKSIFALPLIPSYYKDYSYTTEEESRKSGVNDQMRLINLGLCYNMLIENSSVFVPLSTSGVGWKTSSQPRSFNHVNYKPESWYHSSAILASALDTFTLKYRLKNTCYSLSDFAVDLTPYGRKATAASICLPFSLNTGGYLIDCLDNWEGPLTQSITPNCTIGSSRL-MQLYTLRGVGANQLKKPSSVAGKQL--DMPAYRCNTIDEMLSMYLAYTCHASASNVTSVSKGLQVKKPFPDIFDKRVGRNGNIIADDRNPDMSVQSVPIMTGLHSGSEIGNMIESLHTAMNNIKIARFQQYASAGLEKDEYNECLAKLFDFRELY 545          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAYEGQ--SETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLK-KNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKEDVGEE-IEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPE----------YSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQD--LTSLLP--GIGQESGSVNAQSLVMRGLDRSLLK--PADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            M  + I+++  GHYAN VG+H WNIQE++F Y+    SE  H++L+REG+T   QVTFTPR++ VD + +L  LP  GDLYE    P    + W G  +  +E P + KN FQ ++   NNAS   L  V T      K Y+L+++V+ WSD+LY RFHP++  +++ YQH N   PFD ++LG   WK +V E+   D IR +VE+ D  QGFHILTD  +GF G+++  ++++ DE+  K+ LV PT P  +P+          YS +  STR++N +LS ++  E SS   PL  ++  +  P   R+    QY   L YHSSA +A+ LD+++L +R       + D+   L    RK  A     PF LN    L+D L + +     S+ P   IG E      Q L++RG+  + LK  P    + +    +     KS+++ LE +LA       S V T     S   P+PDLFD R+   G     PR    ++ SVP L    S  +  +  + +     K+ I + ++F     EA   E+++  V+ L+ENY+
Sbjct:    1 MVSKEILTLQFGHYANFVGTHWWNIQESSFQYDSAAPSEIDHNVLFREGITPAGQVTFTPRLLLVDLKNSLKTLPIQGDLYEEPPDPSQLFMKWEGHKIELQEAPRESKNAFQTDI---NNASA--LPTVAT------KKYNLEQDVQVWSDFLYSRFHPRTVNVIKQYQHCNAETPFDSYSLGAALWKSEVFEDRFSDDIRRYVEECDHFQGFHILTDCTNGFAGLSSACLEHIRDEYDRKSVLVLPTIPAHFPDNDFQTAHEQVYSLMNDSTRVINLLLSFNTYREFSSMFVPLCTSEAGWRQPGLPRQFYHTQYNHKLPYHSSAFLAAALDTISLKYRLESSTFSLSDLCADLTANDRKAAAGSLCMPFSLNADADLIDCLDQWEGPLYKSITPRCSIGTERV---MQHLMLRGVPETRLKKPPNKAGKQKAMAAY---NCKSVKDMLELFLACSTYATASHVSTISQAMSTKNPFPDLFDDRIGVHGNVSAIPRLEHTRVESVPILAGLHSGSEIGQMFESLHTEAKKLKIARFNQF---TLEADEYEDALNSVMTLRENYE 546          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAYEG--QSETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDSLNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKEDVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYP----------EYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQD--LTSLLPGIGQESGSVNAQSLVMRGLDRSLLK-PADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQ 546
            MS R I+++  GHY+N+VG+H WNIQE +F Y G  +SE  HD+LYREG T N ++TFTPR++  D +G+L  LP  G L   L+      + W     ++ + P  KN +  +++S N           TS  E KK Y L+E+++TW+DYLY RFHP+S  +L++YQH +  + FDV   G   WK D GE   D IR +VE+ DS+QGF +  D  DGF G+  G +++L DE+  K+ +  P  P  +           + S +  S RL+N  LS+    + +S   PL   +  +  P   R+   + YKP L YHSSAI+AS LD+L+  +R       + DV   L GYGRK+ AA    PF  +  EYL+D L +      TSL P     +  +  Q + +RG+    LK P    + QM  N P    + I+E  E Y         + +   +    V  P+P++F  +L+  G+     R  S+ + S   +  + +     + ++++   V++I   KLH+FE  G E    +ES+ K+   K+NY+
Sbjct:    1 MSTREILTLQFGHYSNYVGAHFWNIQELSFDYTGTVKSEVNHDVLYREGQTSNGEITFTPRLLIADLKGSLKTLPAHGGLENDLST--ADEIPWNSVEKIE-DPPAYKNVYLSDIESEN-----------TSNIENKK-YILEEDIKTWTDYLYPRFHPRSINILKEYQHGSEQESFDVGCTGRLIWKSDYGETFSDNIRKYVEECDSMQGFQVNFDCCDGFSGLALGCIEHLVDEY-TKSIVAHPILPSYFNDNDPTSQEDRDKSTLKDSMRLVNIALSIEELSQHASLFVPLCTGEKGWRKPGAGRRFEHLNYKPELYYHSSAILASALDTLSQKYRHKSNFYSMSDVCADLTGYGRKMAAASLGIPFAFHESEYLIDHLNRSTQPIYTSLTPSCKIATDKI-FQLITVRGIPEHYLKAPLKEAKEQM--NLPAYRCRDIKEMFELYFQANNFLSATNITVCEKPLEVKTPFPNIFSEQLNKHGLLHNDIR--SENMQSCAVISGYHNGNFMADMIEKLHREVSRIKFSKLHKFEEEGLELIDYQESLNKLAEFKDNYE 540          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAY---EGQ---SETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDS-----------------LNNASEKD-LCEVGTSRREA-------KKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAWKE-DVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNPGEYLVDVLQKKQDLTSLLPGIGQESGSVN-----AQSLVMRGLDRSLLKPADFERNQMFVNHPFLGSKSIEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENYQPPSCM 551
            M  R IVS+ +GHY+N VG+H WNIQE++F Y   E Q    E  HDIL+REG T   +VTFTPR+I VD +G+L  L Q G LYE     +   + W+G   + K  P +KN F   LD                  +++   KD L   GT   ++       K D+ LD  V+ WSD+L    HPK+  ++  Y H N+L PFD++  G++A  + +   E+EDRI  F E+ DS+QGFH+L D  DGFGG+ A  + +L DE+ +K+ + F  +P   P+ + +  + R+LNS LS       SS   PL+LA   +     +   P + +K  + YH+SAI+A+ LD+ +LP+R    P  + D+ +    +GRK+ +  +  P  +      +DVL   QDL   LP +       N      QS+V+RG+      P    R+   +   +   +S+ + L+ YL E +  C +      T   V+ P+P +F   ++  G+   T R+    + +VP + + QSS D    L  +     K+NI K  RF  +G E    +E ++  ++L++ Y P S M
Sbjct:    1 MCSREIVSLQIGHYSNFVGTHWWNIQESSFLYSPSEAQIKDKEVNHDILWREGKTFKEEVTFTPRLIAVDLKGSLITLKQEGILYE---TNQQDDIKWSGDITLHKASPAEKNDFLSNLDKEDQAIVECRKRTDTAEVIDDVDVKDTLSRAGTEANKSDSQLVFGKVDHDLDNVVKVWSDFLRVYLHPKTIQIIEQYYHLNSLHPFDIYGAGIKAIDDYETKSEMEDRIHHFCEECDSLQGFHVLVDTHDGFGGVGAQTLQHLADEYTSKSVMTFGFTPANLPDDTPVSRANRILNSALSYQKCFTHSSLFFPLSLANSLWKTLGNYADFPQLDFK-MIDYHTSAILAATLDTASLPYRT-VNPIHMCDITDNFQSFGRKVGSMSSALPICMEADSNFLDVL---QDLQGSLPWLSLTPHCTNQSTPFMQSVVVRGI------PETTPRSPRGI---YSSCRSVNDTLQVYLTENFNSCLNAGTVINTPCKVNTPFPHIFKKNVNKFGLVSTTERSRFQGVETVPMMTSMQSSPDTAVLLNTLYSDAKKLNIRKHTRFLEAGLEEDDYQEILQDFVSLEKCYLPRSDM 571          

Query:    1 MSDRAIVSVHVGHYANHVGSHLWNIQEANFAYE------GQSETCHDILYREGLTLNRQVTFTPRVINVDRQGALGALPQFGDLYEPLTVPKVAGLLWTGATVVQKEEPLKKNPFQLELDS-----LNNASEKDLCEVGTSRREAKKDYSLDEEVRTWSDYLYGRFHPKSNVLLRDYQHKNTLKPFDVFNLGLEAW-KEDVGEEIEDRIRFFVEDADSVQGFHILTDDFDGFGGITAGLVDYLEDEFGNKTRLVFPTSPPAYPEYSGILGSTRLLNSMLSLSSQVEGSSALTPLTLAKDTFVLPNGHRKLPSIQYKPNLMYHSSAIVASVLDSLTLPWRANEKPTRIYDVVNGLNGYGRKICAAKAKFPFVLNP-GEYLVDVLQKKQD---LTSLLPGIGQESGSVNAQSLVMRGLDRSLLKPADFERNQMFVNHPFLGSKS-IEEALEQYLAEQYERCPSVVHTFKTGASVSRPYPDLFDARLSNEGIYRQTPRNASDKLTSVPALVTWQSSQDCQEYLKRMCDRVAKINIHKLHRFETSGCEASVLEESMEKVLALKENY 545
            M+ R IV++ +GHY+N VGSH WNIQE +F Y+      G S   HD+L+REG T    VTFTPR++ +D +G+L  L + G LY      +V    W     + +     KN +  +L+      +++  E ++C         +K Y+LD++V  WSDYL    HPK+  ++ DY   +T +PF+VF +G E + K +  E++EDRIRFFVED D +QGFH L D +DGFGG+ +  + YL+DEF +K++L F  +P   P+ + +  S R++NS +      E S    P++LA   +      +  P +QY   L YH+SAI+AS LD++T+P+R ++  + + D+ +  +  GRK+ A     PFVL      L+D L    +     SL+P +   S   + QS V+RG+    +K      N   ++   L S S  ++ L+QYL + +    +    F     V  P+P++F   ++++G      R     + SVP + + QSS++    +  +     + +I K HRF  SG +  +  + ++ +  L   Y
Sbjct:    1 MAGREIVTLQIGHYSNFVGSHWWNIQEGSFNYDINHVKDGVSLN-HDVLFREGQTTKGAVTFTPRLVCIDLKGSLNTLSKDGGLYGDDNEEEVK---WCEDVTLHEAGTGYKNEYLTDLEQEESVLISDKEENNVCS-------GQKYYNLDKDVTVWSDYLKTYLHPKTLHIINDYMLGDTERPFNVFGMGEEIFSKPETFEDVEDRIRFFVEDCDLLQGFHCLVDTYDGFGGVASTYLQYLQDEFSSKSKLTFGMTPHILPDSTAVERSNRIINSAICYEKLCESSGLFIPISLATSLWRKLGSSQTFPHLQYNVKLNYHTSAIIASTLDTMTIPYRRDDNFSHLTDITSSFSMLGRKVAAINTSLPFVLKEDNSSLIDSLMSYGNDPPWQSLVPHV-TNSTVPDLQSCVLRGISSHTVK----SNNVSSLSRGILASCSNTQDVLQQYLTDVFPNTKNAGCVFNEALPVKAPFPNIFSPSINSKGFLSTRQRLPLQGVESVPMMTSLQSSKEIYNLIHSLYTETTRFDIRKHHRFLQSGLDEDMYRDVLDNLQTLSTAY 546