abnormal spindle-like microcephaly-associated protein homolog, maker-scaffold1923_size24897-snap-gene-0.7 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000008050 (supercontig:LSalAtl2s:LSalAtl2s479:220317:222350:-1 gene:EMLSAG00000008050 transcript:EMLSAT00000008050 description:"maker-LSalAtl2s479-snap-gene-2.31") HSP 1 Score: 156.377 bits (394), Expect = 6.114e-41 Identity = 131/485 (27.01%), Postives = 231/485 (47.63%), Query Frame = 0
Query: 482 RIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLR---KSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFA--QIQASALEELKNYSAILIQSHWRGCVQRGKFLRLR---RTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSEND-RCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLL----ASSNRVKKILTLPLNAKKLLESHKHYHRLH 953
R + E + R +S ++++IQ + R + Q ++ + LR + +MVQ VR ++ +++++R +S +++ + + IQS R A+++F +IQ KN S+++IQS RG +Q+ KF ++ R +++Q++ RR ++M++ ++ V+ Q +I H++ +A IQR+ + W+ RKKF + R V VIQ +RG++ R + N LS EVR ++ AN+ ATE+ KL NR + L LY + +A L+ I+ DLD +TR+S CCDQ++ D + V +LL+L+ RCN+S+PH+++IS +LD INL +YE +R+ + + +T +E L + V I+ K + L++L VKK T + L+E + H LH
Sbjct: 8 RFLAKQEFKRRKILMKKSKSSVVIQFYSRCYLQMEKRLKLRTELRQIVMVQSVVRRYLAKQEFKRRKSQMQMTKSS-----------------------VVIQSYVR---AKQKFKRRKIQME-----KNKSSVVIQSCVRGYLQKKKFKLMKDEIRKVVKVQSMV------RRFLAMKKKQKL---------------------VIGQGSI-------------HFKKQFIFKDDNNLAAICIQRNYRAWIYRKKFKKTIRCVIVIQSMWRGFRTRKSL---------------ICNTRLS----EVRARLVCANKEATENNKLCNRVSYVLYHLYNIKSLAVLIKIVNDLDASTRYSELCCDQMLENGDKKPVIVLLDLILRCNKSVPHIEVISGVLDTLINLVRYERTRL-YISGLRETYKTCLETLQRFEKSHVIIFAKVISFLYVLTFEKGGVEGVKKHFTKKIK-DYLMEYERKKHLLH 400
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000000998 (supercontig:LSalAtl2s:LSalAtl2s116:2039559:2041029:1 gene:EMLSAG00000000998 transcript:EMLSAT00000000998 description:"maker-LSalAtl2s116-augustus-gene-20.15") HSP 1 Score: 120.553 bits (301), Expect = 5.030e-30 Identity = 81/261 (31.03%), Postives = 141/261 (54.02%), Query Frame = 0
Query: 777 KIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSEND-RCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLL----ASSNRVKKILTLPLNAKKLLESHKHYHRLH----NKQMERGRRRNNYLPNS----FRPSPAQAKPKMPKLSLCPPWQIRED-----VIRHHKDPFLASEMVLNKLALKP 1019
++ EVR ++ N+ ATE+ KL NR + L LY + +A L+ I+ DLD +TR+S CCDQ++ D + V +LL+L+ RCN+S+PH+++IS +LD INL +YE +R+ + + +T +E L + V I+ K + L++L A +KK + + L+E + H LH + +G+RR + P S + A+AK K L + ++++D +++ K+ FL ++ L K+ P
Sbjct: 17 RLXEVRARLVCVNKEATENNKLCNRVSYVLCHLYNIKSLAVLIKIVNDLDASTRYSEFCCDQMLENGDKKPVIVLLDLILRCNKSVPHIEVISGVLDTLINLVRYERTRL-YISGLKETYKTCLETLQRFEKSHVIIFAKVISFLYILTFEKAGVEGIKKQFSKKVK-DYLMEYERKKHLLHKSVSKSKNVKGKRRIPHFPESHNCAISATIAEAKRKSDGLQIFLDKKMKKDRSQSRCLKYTKERFLWTQSRLCKVLEMP 275
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000003057 (supercontig:LSalAtl2s:LSalAtl2s172:803529:807762:-1 gene:EMLSAG00000003057 transcript:EMLSAT00000003057 description:"augustus_masked-LSalAtl2s172-processed-gene-7.0") HSP 1 Score: 73.559 bits (179), Expect = 2.222e-13 Identity = 122/502 (24.30%), Postives = 219/502 (43.63%), Query Frame = 0
Query: 248 LNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQ----------SYLRTQN---ACLAIQKYYRSHVARLAF-QAERKLESLA-------ATTIQSAWRRNQVRRERQRIIQTRNE-----------AALVIQSAWRQYQNRLCLERR-----IQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRK----SSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRG---KFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYR 701
L ++A KIQS +R + +R+ + E+ +L K++ +A+ +Q+ +G F+++K +A+ + +L K + +A +IQ+ +R +++R+ L +N A + IQ + AR QA+ L L+ A IQS +R Q R+ T NE AAL IQS +R ++ R ++ + + + +RIQ FR + R ++ L + +R +AI IQSH++G+ R+ I K ++I++Q +R + VR+ D +R +V +IQ R + KRL+E ++ A IQS ++ R +R+ A I+ E +AI IQ ++G R + L I++Q+ ++ ++ L +++A IQR +R R ++ T+SAI IQ +R KAR+ R
Sbjct: 15 LAEAAVKIQSVFRGFQTRKDITKEDVESLPDLND-------------------KELAEAAVKIQSVFRG------FQTRKSAAKEDEEPL----------PNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLNDENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRK-----YITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVGSAIRIQTVFRGYKARKKIRNNL---LLVR--------------SAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKE---IKKTTSAALMIQSCFK-RFKKRKLALIEKQKEEN----AAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQKAALQIQRVYRCFRTKESTEDI------TRSAILIQGAFRGFKARKKAR 445 HSP 2 Score: 70.0922 bits (170), Expect = 2.781e-12 Identity = 113/487 (23.20%), Postives = 219/487 (44.97%), Query Frame = 0
Query: 31 ERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRN----QSATLIQSHWKAHIQREQFC-------------ALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI---MADAQEELRQYSATLIQSQWRSHSERKAFLH----------LRHSTLRIQSEFRKWSAQKRFASMKWAATI-----IQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQA---QWRVWIQLKAYKQMRCSAIVL-QAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYL----RTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR 472
++++ + A +IQS ++ ++R+++ + +L + ++A IQS ++ R+ L A+V +QS FR K+R+R I+ L ++L+E +A IQ + + R+ + + D ++ SA IQS +R RK + L + L+IQS FR + +K+ K A + IQ +R Y+ + + + LL +SA KIQS+++ + R++ + E ++ + +A LIQ+ ++V LK Q R A++L Q+ ++G+ +S +R K + K+ +A IQ+ ++ ++ R+ L + +NA + IQK Y+ R + ++++E+L A IQS++R + R+E ++ +AAL IQ +R ++ + E ++ + IQ FR F R
Sbjct: 12 DKELAEAAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRV-------NNINDHSLPDLNDENLSE---------AAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRKYITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVGSAIRIQTVFRGYKARKKIRNNL---LLVRSAIKIQSHYKGYKVRKALI---NENKKRMR--AAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGY-----------------KSRKRLKEI---------KKTTSAALMIQSCFKRFKKRKLALIEKQKEENAAIQIQKVYKGFKTR---KDKKEMETLMFAVIKIQSSYRSYKRRKE----LEKDQKAALQIQRVYRCFRTKESTEDITRSAILIQGAFRGFKAR 441 HSP 3 Score: 69.3218 bits (168), Expect = 4.547e-12 Identity = 105/467 (22.48%), Postives = 202/467 (43.25%), Query Frame = 0
Query: 144 SATKIQGYWKMWRGRQAFLR----IMADAQEELRQYSATLIQSQWRSHSERKAFL-------------HLRHSTLRIQSEFRKWSAQKRF-------------ASMKWAATIIQRSWRHYRFVQHLHE------RIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQ---SYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCL---ERRIQACVRIQRGFRKFIQR--CCLQRCLSERIALRHEA--------QERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRF 558
+A KIQ ++ ++ R+ + + D ++ +A IQS +R RK+ L + ++IQS FR + ++KR ++ AA +IQ + + + L++ + + L +SA +IQS +R + +R+ Y+ EL + K++ +A+ +Q+ +G+ R++ + +K + V SA RIQT +R ++AR+ + L + + IQ +Y+ + R A E K AA IQS R +VR+ + Q R A ++IQS R Y++R L ++ A + IQ F++F +R +++ E A++ + +++ E+ A I IQS +R + +R+ +K+++ +Q+ R + + E S +IQ A+R F
Sbjct: 18 AAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLNDENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRK-YI-----TNNELPNLDD----------------KKLAMAALKIQSVFRGFRMRKKIDDKKTATLV------------------------GSAIRIQTVFRGYKARKKIRNNLLLVRSAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKEIKKTTSAALMIQSCFKRFKKRKLALIEKQKEENAAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQKAALQIQRVYRCFRTKESTEDITRSAILIQGAFRGF 438 HSP 4 Score: 60.8474 bits (146), Expect = 1.963e-9 Identity = 103/415 (24.82%), Postives = 174/415 (41.93%), Query Frame = 0
Query: 408 AATTIQSAWR----RNQVRRERQRIIQTRN-----EAALVIQSAWRQYQNRLCLERRIQ-------------ACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYI------------GLRKSSIMVQKQVRGWIVRR----------DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNY-----SAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACI-AQRRLVSMRESAR-------IIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRR---AVTVIQKHYRGYQVRTAFKSDCK 758
AA IQS +R R + +E + N EAA+ IQS +R +Q R + + A V+IQ FR F R + + ++ E+ S AAI+IQS + G+ R+ L +S+I +Q RG+ R+ D ++ + IQ +R F + K+++++ L A +IQ+++R AR++ ++N SAI IQSH++G R + + +R L ++CI A + +++E + +IQ R ++ + L E++K T +A+ IQS ++ K R+ LA E A IQ+ + + RK + AV IQ YR Y+ R + D K
Sbjct: 18 AAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLND-------ENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRKYITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVG-SAIRIQTVFRGYKARKK-----------IRNNLLLVRSAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKEIKK---TTSAALMIQSCFKRFKKRK-------LALIEKQKEENAAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQK 403
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000011962 (supercontig:LSalAtl2s:LSalAtl2s84:1272304:1281371:-1 gene:EMLSAG00000011962 transcript:EMLSAT00000011962 description:"maker-LSalAtl2s84-snap-gene-12.11") HSP 1 Score: 63.1586 bits (152), Expect = 3.868e-10 Identity = 49/145 (33.79%), Postives = 76/145 (52.41%), Query Frame = 0
Query: 512 WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREF-----------AQIQA-----SALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAK 640
+ ++ R L IM+QK V+GW+ R+ Y R ++ R++QR R F +R+ MR R Q A KIQ+ R + R+ F A+I+ + +E LK AILIQ H RG +QR K+L+ R I +Q++ +
Sbjct: 736 YMEKLRSEKLMACGIMIQKHVKGWLARKKYIRLLTATRLLQRLSRGFIARRRI---FHMR-RLQAAVKIQAFIRGXLRRKSFNRTKELTIGLQARIRGYNARKNHIEFLKEKKAILIQKHVRGFLQRSKYLKNRNQVILVQSIVR 876
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391789|sp|P62292.1|ASPM_MACMU (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 242.662 bits (618), Expect = 2.531e-64 Identity = 298/1227 (24.29%), Postives = 555/1227 (45.23%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY------RHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ +SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A IQ + R R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM+ Y + Q + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F +K + TIQ+A+R +VR ++ +I+ AA+V QSA W + + C + + +A V IQ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ + R+ IQRA++ + +++ + S I IQ +R ++ + + + H + A + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYRANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITIQSSYCTIR------RLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQK----SVRTIQAAFRGMKVR-QKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAVLLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3477 HSP 2 Score: 159.844 bits (403), Expect = 3.304e-38 Identity = 213/838 (25.42%), Postives = 391/838 (46.66%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++ Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMCKAIMVIQNYYHAYKAQVNQRKNFLRVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 151.754 bits (382), Expect = 9.756e-36 Identity = 221/909 (24.31%), Postives = 409/909 (44.99%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSER---------------------------KAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAW---RRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G Q++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ K + LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q + +QR+ + Q+RSA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA TIQS++ RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R + Y++ + + ++IQ + R ++ + L+H L + + F + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYRANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITIQSSYCTIRRLMVKKK----LQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKY-------RANKKKQKALQH------NELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIV 2773 HSP 4 Score: 139.043 bits (349), Expect = 8.581e-32 Identity = 194/731 (26.54%), Postives = 340/731 (46.51%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRG----WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS A++R AA +I K+W+ L Q+ L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW +K + +K A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ +MRL+ + +QS +RMR AR+ + ++ A+ ++NY ++ QR FLR+++ LQA + ++ + +A IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1261 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLC--RQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQLQKYKKMKK----AAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRK-----------------------------QMRLQRKAVISLQSYFRMRKARQYYLKM-CKAIMVIQNY----YHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN------KRVKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFR 1918 HSP 5 Score: 125.561 bits (314), Expect = 9.490e-28 Identity = 170/653 (26.03%), Postives = 303/653 (46.40%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWR---------------RHRLIRHLAELQKYKVMTQ------SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + A++R AA IIQ+ WR R + L + ++ N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR +++ K Y+ ++ S++++Q+ + W +RR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + + Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I +Q+H R Q Q+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R AR+ + I S ++ IQS++R V + +FL L+ T I+LQ++ K +++ + +R +A IQ+ +R R I+ A ++ Y V Q + I++QS +RM KAR++Y + A IQ + RK F+R+++A T +Q YRGY+VR K
Sbjct: 1260 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKW-KRRKMQSQVKATVILQRAFREW-------HLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKLQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGM-----------------------------QARKVYIHILTSVIK---------IQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMCK-------AIMVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIK 1822
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391788|sp|P62291.1|ASPM_MACFA (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 241.891 bits (616), Expect = 3.956e-64 Identity = 297/1227 (24.21%), Postives = 555/1227 (45.23%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY------RHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ +SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A IQ ++ R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM+ Y + Q + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F +K + TIQ+A+R +VR ++ +I+ AA+V QSA W + + C + + +A V IQ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ + R+ IQRA++ + +++ + S I IQ +R ++ + + + H + A + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQK----SVRTIQAAFRGMKVR-QKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAVLLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPXTPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3474 HSP 2 Score: 159.458 bits (402), Expect = 3.821e-38 Identity = 212/838 (25.30%), Postives = 391/838 (46.66%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R Q++ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++ Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHIRKHQQVQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQXKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 155.992 bits (393), Expect = 4.981e-37 Identity = 221/906 (24.39%), Postives = 407/906 (44.92%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSER---------------------------KAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + +CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G Q++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ K + LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q +QR+ + Q+RSA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA TIQS++RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R + Y++ + + ++IQ + R ++ + L+H L + + F + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQXKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHXXHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVXVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITIQSSYRRLMVKKK----LQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKY-------RANKKKQKALQH------NELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIV 2770 HSP 4 Score: 131.339 bits (329), Expect = 1.676e-29 Identity = 205/798 (25.69%), Postives = 363/798 (45.49%), Query Frame = 0
Query: 21 LVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQK---HLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRG----WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATK-------IQSLWRMRMA----RREFAQIQASA--------------LEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKA--CIAQRRLVSMRESARIIQ-----RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKK----FIRIRRAVTVIQKHYRGYQVR 750
L RL +L RK + A IQ+ W+ + KL +LKR+Q +R++ A+ ++QS A++R AA +I K+W+ L Q+ L + + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW +K + +K A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ R +V +Q +R MR Q+ K IQ+ + A R+ F +++ +A L + ++ +A+ IQS +RG +R K+ + ++ I++Q +A + R ++ A ++ R W+ + IR Q+A+ IQS +RM KA++ +R + A IQ++ + W +K +I +R AV ++Q ++G +R
Sbjct: 1256 LCARLLDL---RKEIRAARLIQTTWR----------KYKLKTDLKRHQ-------------ERDK------AARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNL--CRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQVQKYKKMKK----AAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFR-------------MRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRKQIRR---------EHQAALKIQSAFRMAKAQKQFRLF-------KTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLR 1964
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391784|sp|P62287.1|ASPM_COLGU (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 238.424 bits (607), Expect = 5.968e-63 Identity = 296/1228 (24.10%), Postives = 553/1228 (45.03%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRM-----------WMSR--RSYLRFQTEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++M R R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A +Q ++ R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM W ++ + R + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR ++ R F A +K + TIQ+A+R +VR++ + I + + AA+V QSA W + C + + +A V IQ+ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R ++ + + E G + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMQRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITVQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQAAYKGMKARQHLREK------HKAAIIIQSTYRMHRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNMQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTVVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYIRVKTERKIFLAVQK----SVRTIQAAFRGMKVRQKLKNISEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVTIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFRRMVTRKVETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGGFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYYSIEKIEHEGQECLSQRNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCVDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 162.925 bits (411), Expect = 3.410e-39 Identity = 215/838 (25.66%), Postives = 392/838 (46.78%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + +KF++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKFQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKIATQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQ---AAYRGYKIRQLIKQQSIAAVKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 151.369 bits (381), Expect = 1.361e-35 Identity = 222/907 (24.48%), Postives = 409/907 (45.09%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSERKAF---------------------------LHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQ-SLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G +++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ F LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q + +QR+ + Q+ SA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA T+QS++RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R Y++ + + ++IQ +R ++ + +E++ T +Q S M M ++ Q QA AI+IQ H + R +L LR T + +Q R+L +R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ ++++ RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATYIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQREKYLTILKAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMQRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITVQSSYRRLMVKKK----LQEMQRAAVLIQATFRMHRTYVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQAAYKGMKARQHLREKHKAAIIIQSTYRMHRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKE----TCVQASFQDMNMQKQIQEQHQA----------AIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTVVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYIRVKTERKIFLAVQKSVRTIQAAFRGMKVRQKLKNISEEKMAAIV 2770 HSP 4 Score: 142.51 bits (358), Expect = 6.607e-33 Identity = 201/737 (27.27%), Postives = 342/737 (46.40%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWR----GWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAIL-IQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS A++R AA +I K+W+ L Q+ L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW Q++ S A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ +MRL+ + +QS +RMR AR+ + LK Y AI+ IQ+++ QR KFLR+++ LQA + R+L+ + A + IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1261 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWK-QRKMQSQVKATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLC--RQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHIRKHQQLQKYKKMKK----AAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIATQKREEYMQMRESCIKLQAFVRGYLVRK-----------------------------QMRLQRKAVISLQSYFRMRKARQYY----------LKMYKAIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQAAYRG-YKIRQLIKQQSIAAVKIQSAFRGYN------KRVKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFR 1918 HSP 5 Score: 122.094 bits (305), Expect = 1.113e-26 Identity = 176/642 (27.41%), Postives = 307/642 (47.82%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW------ATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + A++R AA IIQ+ WR R + L + ++ N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR +++ K Y+ ++ S++++Q+ + W QR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + + Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I Q+H R Q Q+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS + R ++L LR + +Q +K Q+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM KAR++Y + A IQ + RKKF+R+++A T +Q YRGY++R K
Sbjct: 1260 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKQRK-MQSQVKATVILQRAFREW-------HLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKFQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYIHILTSVIKIQSYYRAYVSKKEFL--------SLKN-ATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIATQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKARQYYLKMYK-------AIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQAAYRGYKIRQLIK 1822 HSP 6 Score: 94.7449 bits (234), Expect = 3.236e-18 Identity = 146/585 (24.96%), Postives = 266/585 (45.47%), Query Frame = 0
Query: 1 MYLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAH----IQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSH----SERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAER--KLESLAATTIQSAWRRNQVRRERQRIIQTRNE--------------AALVIQSAWRQYQNRLCLERRIQACVRIQRGFR-KFIQRCCLQRCLS-ERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFA 559
++L +Q+SV IQ ++R + Q+L+ + E+ A QS +RS+ + E +++ T IQ +KA Q ++ + A+V +Q FR+ R+ T K AA I + + ++++ ++ R+A +Q Y++ W+ R+ FL L + +A ++Q+ +R+ +R+ +L +R S + IQ+ + + +++F +K + IQ WR YR ++L + ++A KIQ+++R W + + YL LKA K ++Q ++R F + + SA ++QR WR + H + H++A IQ +R ++ RQ +LR ++A L IQKY R AR A + ER +E +T I A R + R+RI++ R + AL IQ A++ Y +++ + + IQR FR + Q+ +Q+ S E+I HE QE +QR R ++ ++QK VR +++R+ E+ S + IQ WR ++
Sbjct: 2734 IFLAVQKSVRTIQAAFRGMKVRQKLKNISEEK---MAAIVNQSALCCYRSKTQ--------YEAVQSEGVT-IQEWYKASGLACSQEAEYHSQSRAAVTIQKAFRRM-VTRKVETQKCAALRIQFFLQMAVYRRRFVQQ------KRAAITLQHYFRTWQTRKQFL---------LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCK-------VKAACKIQAWYRCWRAHKEYLAI-------------------------LKAVK-------IIQGGFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIR---AREAGKRERIKYIEFKKSTVILQALVRGWL--VRKRILEQRTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQQKKFIQKYYSIEKI--EHEGQE-------------------CLSQRNR------AASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYS 3219
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391780|sp|P62283.1|ASPM_AOTVO (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 237.654 bits (605), Expect = 9.569e-63 Identity = 298/1223 (24.37%), Postives = 555/1223 (45.38%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHC----SATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRL-------------------CL--------ERRIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHKHY---HRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L LQ + IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ ++++++QS FR RRRF+++K+AA I + ++ + KH ++H L + ++A IQ ++ R+M + + +A LIQ+ +R H F +H+++ IQ +R + A Q+ + +W +A IIQ ++R + Q L E+ +++A IQS +RM+ Y + Q + + L+H + T +QA ++ + +K ++ ++I++Q K + ++ + + +QR +R+ V QS K +R MH +ATRIQ+ +RM +A Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + Q + AA+V QSA Y+++ CL + +A V IQ+ FR+ I R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q +++G+I +R +++ R+S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR L+++ + LQAL + + ++R++ R R++ +A R R + L+K S I IQ +R ++ + H E G + IQ++++ +++R+K + + Q +RGY R +DC KI+ +R + + N E+ KL RTALAL L + ++ +L +K L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +YR DKS I+TKT LL LL ++NR + + ++ +K H+++ +++ +++++ + F P + +L P W +R D + +P A +M+++ L +
Sbjct: 2304 FLRLQNAAIKIQSSYRRWMIRKKIREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKH---KLHQFLQLRKAAITIQSSYR---------RLMVKKKLQEMHRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSAVIIQAAYRGMKARQLLREK------HKAAIIIQSTYRMYRQCCLYQKLQWATKIIQEKYRANKKKHKALQHNELKKAETCLQASFQD-MNIKLIQEQDQTSIIIQKHCKAFKIKKHYLHLRAPVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHLAATRIQSFYRMHRATVDYQTKKTAVVLIQNYYRLYVRVKTERKSFLAVQK----SVRTIQAAFRGMKVRQKLKNVSQEK-MAAIVNQSALCCYRSKAQYEAVRSEGVIIQEWYKASCLACSQEAEYHSQSRAAVTIQKAFRRMITRKVETQKCAALRIQFFLQMAVYRRRFVQQKRAAVTLQHYFRMWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLRIRSSVIIIQARIKGFIQKRKFQKIRNSTIKIQAMWRRYRAKKSLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNLRASAIIIQRKWRAILSAKIAHEHFLMIQRHRAACLIQAHFRGYKGRQVFLRQKSAALNIQKYIRAREAGRRERIKYIELKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLKALRIQRAYKLYLALKKANKQINSVICIQRWFRARLQQKRFIQKCHSIKKIEHEGQERLSQQNRAASVIQKAVRHFLLRRKQEKFTSGIIKFQALWRGYSWRK--NNDCT------------------KIKAIRLSLQVVNREIREENKLYRRTALALHYLLTYKHLSAILEAVKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYREKPGNKVADKSGSIFTKTCCLLATLLKTTNRASDVRSRSKVVDRIYSLYKLTACKHKVNTERLLYKQKKDSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNLEEIINPLQAIQMLMDTLGI 3471 HSP 2 Score: 162.155 bits (409), Expect = 5.653e-39 Identity = 218/840 (25.95%), Postives = 392/840 (46.67%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
R+ +IQ +WR+Y L + L + L +K+N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK SV+LQS R A + AA I + W+ L +K +R ++ S+ IQ ++ W+ R+ L++ A Q R++ SA +IQS +R H + + ++++R + IQ FR + AQK + K + IQ+ +R Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+ +Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + L IQ+ YRS +LA Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + +R + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +IQ H R G QR +++ LR + + LQ++ K +R+L + A IIQ R H + +K+K+M ++ + IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + +
Sbjct: 1264 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLTKQRLRKKLN-AALVIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSVILQSRIRMIIAVTCYKRYLWAAVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQAMFRRWKRRKMQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLQKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYMKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRKIRAACVIQSYWRMRQDRVRFLNLKKIIIK---------LQAHVRKHQQLQKYKKMKKAAVTIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATVKLQSIVKMKQTRKQYLHLRATVLFIQRCYRS--KKLAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAAVKIQSAFRGYRKRVKYQSVLQSIIKIQRWYRAYKTLSDIRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAAMKIQSAFRMAKAQKQFRLFKTAAL---------VIQQHLRAWTAGRKQRMEYIELRHSVLMLQSMWKGKTLRRQLQRQHKCAVIIQSYDRMH------VQQKKWKIMKKAVLLIQKYYRAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKY 2059 HSP 3 Score: 141.354 bits (355), Expect = 1.644e-32 Identity = 202/813 (24.85%), Postives = 388/813 (47.72%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSL-VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKA----RRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR-------QAFLRI---------MADAQEELRQYSATLI--QSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQ---RSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGW-IQRRQ---FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRS-HVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKF----IQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVR----RDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKA----RRHY--------------------RHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
YL L+ +V IQR +R L Q+ EE + ++ + ++Q+F + + R+++ + K + L QS+++ R+ + + A +++Q+++ KA R+ FL +K+AA + ++G ++ + ++ + +A KIQ ++ +R R Q+ ++I ++D + + A +I QS +R RK + ++IQS FR AQK+F K AA +IQ R+W R +R+++ L S +QS W+ RR Q + +H A +IQ+ R+ +Q K +K M+ + +++Q + + I R Q + K + LQ ++R K + + K +++A IQ+++R ++ ++ Y + + + IQ++YR + ++ L+ A IQ+ +R +VRR IQ + AA I++ ++ +Q+R+ +A + IQ +R + +QR + L L +A R R+L AA LIQS++R + Q+ + L+K + VQ++ R R + Y + R SV IQ A+ + ++ + ++ H AT IQ +R M RR F ++ +A+ + Y A L H +FLRL+ I++Q+ + + ++++ M +A IQ +R HR+ H+ +Y+ + Q+++ IQ ++ ++A R+HY RHL + +SA + IQ + +VR++FI +++A IQ+ YR
Sbjct: 1694 YLHLRATVLFIQRCYRSKKLAAQKREEYM---QMRESCIKLQAFVRGYLVRKQMRLQRKAVISL---------QSYFRMRKARQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQ------SIAAVKIQSAFRGYRKRVKYQSVLQSIIKIQRWYRAYKTLSDIRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAAMKIQSAFRMAKAQKQFRLFKTAALVIQQHLRAWTAGR-----KQRMEYIELRHSVLMLQSMWKGKTLRR---------QLQRQHKCAVIIQSYDRMHVQQKKWKIMKKAVLLIQKYYRAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRI------KDCNKAAITIQSKYRAYKTKKKYAACRASAIIIQRWYRGIKITNHQYKEYLNLKK-TAIKIQAVYRGIRVRRH----IQHMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQRENYLKILKAVNVL--QANFRGVRVRRTLRKLQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAVKERNIQFQRYNKLRHSVIHIQ------AIFRGMKARRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWVQRKYRAHLCTKH------HLQFLRLQNAAIKIQSSYRRWMIRKKIREMHRAATFIQATFRMHRV--HM----RYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAIL----IQSRFRSLLVRRRFISLKKAAIFIQRKYRA 2439 HSP 4 Score: 137.117 bits (344), Expect = 2.754e-31 Identity = 208/873 (23.83%), Postives = 399/873 (45.70%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE---------LLRRLKLALELKRNQ---------SATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL----------AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEE--------QSEMRL--------RHQWATK-IQSLWRMRMARREFAQ----------IQAS------ALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ SV ++Q W+ +L ++L+ + ++CA IQS+ +MH +++ L+++ A + R Q + +QS ++ R++ A++ +QS +R K ++++ + +A +I +W++G H + +L+L ++A KIQ ++ R R+ F++ M + +Y + +IQ ++R++ + R+ +L + + +Q+ FR ++ ++ AAT+IQ ++R YR ++ F L + +Q +R R Q + +L H S IQA +R + K M +A ++Q + + + RR+F S K++A +QR +R + HHL++ R+ +A +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + + IQ FR FIQR C + L + + LR A + R + AA+LIQ+ +R + + +SI++Q+ R + + R +Y + S +IQ A+R + L E QS R+ + QWATK IQ +R + + Q +QAS L + ++ ++I+IQ H + + +L LR + +Q R+L ++R A I IQ +R ++ R + M +A IQS +RMH+A Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1940 YIELRHSVLMLQSMWKGKTLRRQLQ------RQHKCAVIIQSYDRMHVQQKKWKIMKKAVLLIQKYYRAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKYAACRASAIIIQRWYRGIKITNH-QYKEYLNL-KKTAIKIQAVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQRENYLKILKAVNVLQANFRGVRVRRTLRKLQIAATLIQSNYRRYR------QQTYFNKLKKITKTVQQRYRAVKERN----IQFQRYNKLRH-SVIHIQAIFRGMKARRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWVQRKYRAHLCTK---HHLQFLRLQNAAIKIQSSYRRWMIRKKIREMHRAATFIQATFRMHRVHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMKTRRHLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKHKLHQFLQLRKAAITIQSSYRRLMVKKKLQEMHRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSAVIIQAAYRGMKARQLLREKHKAAIIIQSTYRMYRQCCLYQKLQWATKIIQEKYRANKKKHKALQHNELKKAETCLQASFQDMNIKLIQEQDQTSIIIQKHCKAFKIKKHYLHLRAPVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHLAATRIQSFYRMHRATVDYQ-------TKKTAVVLIQNYYRLYVRVKTERKSFLAVQKSVRTIQAAFRGMKVRQKLKNVSQEKMAAIV 2766 HSP 5 Score: 80.1073 bits (196), Expect = 7.637e-14 Identity = 121/447 (27.07%), Postives = 193/447 (43.18%), Query Frame = 0
Query: 358 SATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRII-----QTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQR----QRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMR--------------MARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQA-------------LAKACIAQR---------RLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
+A IQT WR ++ + R Q A + + + L Q RK + AA IQ WRR +++ + + +N+AA +IQ WR+Y R + V +Q R I C +R L W AA+ IQ HWR + +R QRY L+ SS+++Q R W RR + + +QRA+R + L KR +E+ A IQS +RM + ++ F QA L + + S + IQ ++R G ++R +L+ R I+LQA + AC+ Q R +++++ +Q R+H+ +LQKYK M ++A+TIQ+ ++ + R SA + + R MQ RK +I I +V IQ +YR Y + F S
Sbjct: 1265 AARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLTKQRLRKKLN-AALVIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSVILQSRIRMIIAVTCYKRYL--------------W------AAVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQAMFRRW-KRRKMQLQVKATITLQRAFREWHLRKRAKEEKS-------AIVIQSWYRMHKQLQKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYMKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRKIRAACVIQSYWRMRQDRVRFLNLKKIIIKLQAHVRKHQ------QLQKYKKMKKAAVTIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQ---ARKMYIHILTSVIKIQSYYRAYVSKKEFLS 1673
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391793|sp|P62296.1|ASPM_SAIBB (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.572 bits (597), Expect = 9.439e-62 Identity = 302/1231 (24.53%), Postives = 548/1231 (44.52%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQT----------------EAQEELEHC----SATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-------------------NRLCL--------ERRIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATK-IQSLWRMRMARREFAQIQASAL----------------EEL----KNYSAILIQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKL-----LESHKH---YHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L LQ + IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R + ++ ++++++QS FR RRRF+++K+AA I + ++ + KH +H L + ++A IQ ++ R+M + + +A LIQ+ +R H F +H+++ IQ +R + A Q+ + +W +A IIQ ++R + Q L E+ ++A IQS +RM+ R Y +Q + + L+H + +QA ++ K ++ +++ +Q + ++Q+ + +QR +R+ V QS K +R MH +ATRIQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + Q + AA+V SA Y+ CL + +A V IQ+ FR+ I R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R +++ ++S IQ WRR+ K L + W A K IQ + ++ R F ++ASA+ E ++ +A LIQ+H+RG R FLR L+++ + LQAL + + ++R++ R R++ +A R R + L+ SAI IQ +R ++ + + H E G + IQ++++ +++RKK + + Q +RGY R +DC KI+ +R + + N E+ KL R ALAL L + ++ +L +K L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +YR DKS I+TKT LL LL ++NR + + ++ L ++KH RLH KQ + ++P +P + + L P W +R D + +P A +MV++ L +
Sbjct: 2299 FLRLQNAAIKIQSSYRRWVVRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMETRRRLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKH---NLHQFLQLRKAAVTIQSSYR---------RLMVKKKLQEMHRAAVLIQATFRMHKTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSALIIQAAYRGMKARQLLREK------RKAAIIIQSTYRMY---RQYCLYQNLQWATKIIQEKYRANKKKHKALQHNELKKAEACVQASFQDMNIKKLIQEQHQTSLTIQKHCNAFKIKKQYLHLRAPVVSIQRRYRKLTAVHTQAVICIQSYYRGFKVRRDIQNMHLAATRIQSLYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERNSFLAVQK----SVRTIQAAFRSMKVRQKLKNLSQEK-MAAIVSPSAVYCYRIEAQSEAVGSEGVIIQEWYKTSCLAHSQEAEYHSQSRAAVTIQKAFRRMITRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAVTLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARTKGFIQKRKFQKIKNSTIKIQAVWRRYRDKKSLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGSFYXKLERTRFLNMRASAIIIQRKWRAILSAKIAHEHFLMIQRHQAACLIQAHFRGYKGRQVFLRQKSAALNIQKYIRAREAGRRERIKYIELKKSTVTLQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLKALRIQRAYKLYLALKNANKQVNSAICIQRWFRARLQQKRFIQICHSIKKIEHEGQERLSQQNRAASVIQKAVRHFLLRKKQEKFTSGIIKFQALWRGYSWRK--NNDC------------------TKIKAIRLSLQVVNREIREENKLYRRAALALHYLLTYKHLSAILEAVKHLEVVTRLSPFCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYREKPGNKVADKSGSIFTKTCCLLATLLKTTNRASDVRSRSKVVDRIYSLYKLTAYKHKVNTERLHYKQKKDSSTSIPFIPE----TPVRTRIVS---RLKPDWVLRRDNLEEITNPLQAIQMVMDTLGI 3467 HSP 2 Score: 163.31 bits (412), Expect = 2.377e-39 Identity = 217/839 (25.86%), Postives = 392/839 (46.72%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
R+ +IQ +WR+Y L L+ +I IN A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S+VLQS R A + A I + W+ L +K +R + S+ IQ ++ W+ R+ L++ A Q R++ SA +IQS +R H + + ++++R + IQ FR + AQK + K + IQ+ +R Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ RM Q R+ YL + L IQ+ Y H +LA Q + + + I+ A+ R + R++ R+ + +A + +QS +R ++R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+++R +Y + +S I +Q+ R + +R + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +IQ H R G QR +++ LR + + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R +H +L A A T+Q + + VRK+ +A IQ YR Y+ + +
Sbjct: 1259 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQR--YEKLKSSSLIIQAMFRRWKQRKMQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLRKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRQIRAACVIQSYWRMRQDRVRFLNLKKIIIK---------LQAHVRKHQQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVRMKQTRKQYLHLRATALFIQQCY--HSKKLAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKSRQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSVAAVKIQSAFRGYSKRVKYQSVLQSIIKIQRWYRAYKTLHGIRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAAMKIQSAFRMAKAQKQFRLFKTAAL---------VIQQHLRAWTAGRKQRMEYIELRHSVLMLQSMWKGKALRRQLQRQHKCAVIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGRE-QHCLYLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKY 2054 HSP 3 Score: 132.109 bits (331), Expect = 1.114e-29 Identity = 212/893 (23.74%), Postives = 398/893 (44.57%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAH-IQREQFCA-LKT-------------------------ASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL---------------------------------AAILIQSHWRGW----TQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQ---RAWRRFALIKRLEEQSEMRLRHQWATK-IQSLWRMRMARREFAQ----------IQAS-------ALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ SV ++Q W+ +L ++L+ + ++CA IQS+++MH +Q+ + +K ++A LIQ +++A+ I REQ C LKT A++ +QS +R K ++++ + +A +I +W++ H + +L+L ++A KIQ ++ R R+ F++ M + +Y + +IQ ++R++ + R+ +L + +Q+ FR ++ ++ AAT+IQ ++R YR ++ F L + +Q +R R Q + +L H S IQA +R + K M +A ++Q + + + RR+F S K++A +QR +R + HHL++ R+ +A +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + + IQ FR FIQR C + L + + LR A + R + A+ILIQ H+R + QR+ Y S++++Q RG R+ R + +IQ R +R++ L + L QWATK IQ +R + + Q +QAS L + ++ +++ IQ H + ++L LR + +Q R+L ++ A I IQ +R ++ R + M +A IQSL+RMH+A+ Y+ + + A IQ +++V R F+ ++++V IQ +R +VR K+ + K A++
Sbjct: 1935 YIELRHSVLMLQSMWKGKALRRQLQ------RQHKCAVIIQSYYRMH-VQQKKWKIMK--------KAALLIQKYYRAYSIGREQHCLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKYAAYRASAIIIQRWYRSIKITNH-QYKEYLNL-KKTAIKIQAVYRGIRVRRHIQCMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQREDYLKFLKAVNVLQANFRGVRVRRTLRKLQIAATVIQSNYRRYR------QQTYFNKLKKITKTVQQRYRAVKERN----IQFQRYNKLRH-SVIHIQAIFRGMKVRRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWIQRKYRAHLCTK---HHLQFLRLQNAAIKIQSSYRRWVVRKKMREMHRAATFIQATFRMHRVHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMETRRRLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKHNLHQFLQLRKAAVTIQSSYRRLMVKKKLQEMHRAAVLIQATFRMHKTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSALIIQAAYRGMKARQLLREKRKAAIIIQSTYRMYRQYCLYQNL----------QWATKIIQEKYRANKKKHKALQHNELKKAEACVQASFQDMNIKKLIQEQHQTSLTIQKHCNAFKIKKQYLHLRAPVVSIQR------RYRKLTAVHTQAVICIQSYYRGFKVRRDIQN------MHLAATRIQSLYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERNSFLAVQKSVRTIQAAFRSMKVRQKLKNLSQEKMAAIV 2762 HSP 4 Score: 120.553 bits (301), Expect = 3.810e-26 Identity = 197/736 (26.77%), Postives = 349/736 (47.42%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSA-ILIQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS ++R AA +I K+W+ L QK L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR+ RK + L+ S+L IQ+ FR+W +K +K A +QR++R + HL +R + +SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H Q RK + + AA IQ+ ++ R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + E ++L++ A I +QS R R++Y+ LR +++ +Q+ + R +Y + R S +Q A+ R L+++ +MRL+ + +QS +RMR +R+ + LK Y A I+IQ+++ QR FL++++ LQA + R+L+ + A + IQ A+R + ++ KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1252 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQRYEKLKSSSLIIQAMFRRWKQRKMQLQVK-ATITLQRAFREW----HLRKRAK---EEKSAIVIQSWYRMHKQLRKYVYVRS---------CVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLH--RQIRAACVIQSYWRMRQDRVRFLNLKKIIIKLQAHVRKH------QQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSK-------KEFLSLKN-------------ATIKLQSIVRMKQTRKQYLHLRATALFIQQCYHSKKLAAQKREEYMQMRESCIKLQ-AFVRGYLVRK-----QMRLQRKAVISLQSYFRMRKSRQYY----------LKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRG-YKVRQLIKQQSVAAVKIQSAFRGY------SKRVKYQSVLQSIIKIQRWYRAYKTLHGIR--THFLKT-KAAVISLQSAYRGWKVRKQIRREHQAAMKIQSAFRMAKAQKQFR 1909 HSP 5 Score: 118.242 bits (295), Expect = 1.754e-25 Identity = 173/658 (26.29%), Postives = 298/658 (45.29%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWR-------HYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR------RFKFVQSLAHHLKWKRMHQSATR----------IQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW------ATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + ++R AA IIQ+ WR + ER+Q N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR ++ K Y++++ S++++QA + W QR+ + Q ++ LQR++R R K +S W RMH+ + IQ ++R +QA++ Y R + + L IQKYYR+++ + + AA +Q+A+RR + ++I AA VIQS WR Q+R+ +F+ L++ + I +Q+H R Q ++Y ++K+++++Q + +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS R R ++L LR T + +Q +K AQ+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM K+R++Y + A IQ + RK F+++++A T +Q YRGY+VR K
Sbjct: 1251 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQ----NKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQRYEKLKSSSLIIQAMFRRWKQRK-MQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLRKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRQI-----RAACVIQSYWRMRQDRV-----------------RFLN---LKKII-----------------------IKLQAHVRKHQQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYIHILTSVIKIQSYYRAYVSKKEFL--------SLKN-ATIKLQSIVRMKQTRKQYLHLRATALFIQQCYHSKKLAAQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKSRQYYLKMYK-------AVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIK 1813
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391787|sp|P62290.1|ASPM_HYLLA (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.187 bits (596), Expect = 1.360e-61 Identity = 296/1222 (24.22%), Postives = 541/1222 (44.27%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQK----RFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-RKFIQRCCLQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ ++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A K + +A +IQ +++ + Q L E+ +++A IQS +RM+ Y + Q + Q+ +H T +QA ++ K + +AI++Q K + R+ + + + +QR R+ V QS K +R MHQ+AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + + R AA+V QSA W + C + + +A V IQ+ F R ++ Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R +++ ++S IQ WRR K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R++ A R R + ++ S I IQ +R ++ + H E G + IQ+++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLXSMHFSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFRTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKQQKAFQHNELKKETCVQASFQDMNIKKQIXEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRHRKLAAVRTQAVICIQSYYRGFKVRRDIQNMHQAATLIQSFYRMHKAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEER-MAAVVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKCAALRIQFFFQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQQIKNSTIKIQAMWRRXRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRIIEQRAKIRLLHFTAAAYYHLNALRIQRXYKLYLAVKNANKQINSVICIQRWFRARLQQKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVXHFLLRKKQEKFTNGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 157.532 bits (397), Expect = 1.638e-37 Identity = 208/841 (24.73%), Postives = 383/841 (45.54%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKR-----------------------NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHER-------IQFRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ ++ ++ A IQS ++Q L +R+ AL +++ N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y +L +R FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A IQS +RM A+ +F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K M ++A+ IQ +R + R HL ++A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKR---HQETDKAARIIQSAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATIILQRAFREWHLRKQAKEENSAIVIQSWYRMHKELRKYIYIRSCXVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIRLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHVRKHQQLQKYKKMKKAAVIIQTHFRAXIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRXQYLHLRAAALFIQQCYRS--KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSMLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALTIQSAFRMAKAQXQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKTMKKAALLIQKYYRAYSIGREQ---NHLYLKTKVAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 139.043 bits (349), Expect = 7.747e-32 Identity = 198/798 (24.81%), Postives = 374/798 (46.87%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKM------WRGR-------QAFLRIMADAQEELRQY-----SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKW--KRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQR----RLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMW----VVRKKFIRIRRAVTVIQKHYRGYQVR 750
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ + QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L +R H + A IQ Y++M W+ Q + R + +E+ Y + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H++ + L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +QR ++ + ++ ++LQ S+R + ++W ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA VIQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q Y+ +R++ +L+ Q +R RH A +Q+ +R RR + ++SA LIQS +R + R +F+ L++ I +Q +A I + + + +R++A IQ ++RR + + L E+Q+ +A+ IQ+ +RMH+ +R H A IQ+ + + + R+ +IR + VIQ Y+G + R
Sbjct: 1844 YQSMLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSAYRGWKVRKQIRRE---------HQAALTIQSAFRMAKAQXQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQL-QRQH-----KCAIIIQSYYRMHVQQKKWKTMKKAALLIQKYYRAYSIGREQNHLYLKTKVAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKK--YLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQREKYLTILKAVKILQASFRGVR--------VRWTLRKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATVIQRRFRT----LMMRRRFLSLKKTAIWIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQALKQASVVIQQQ---------YQANRAA---------------KLQRQHYLRQRHS-AVILQAAFRGMKTRRHLXSM---------HFSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQR------AAVLIQATFRMHRTYITFRTWKH-------ASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKAR 2547
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391790|sp|P62293.1|ASPM_PANTR (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.187 bits (596), Expect = 1.373e-61 Identity = 294/1228 (23.94%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQK----RFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A K + +A +IQ +++ + Q L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F + + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRSIP M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAVVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAECHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 169.474 bits (428), Expect = 3.278e-41 Identity = 209/840 (24.88%), Postives = 392/840 (46.67%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA------------QEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAF----QAERKLESL---------------AATTIQSAWRRNQV-RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR---------------------------------KFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R+ ++ A ++ Q SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++ ER + +A ++Q+ +R + Y + + +A +IQ+ WR+ + ++ + I LQA V+ QR++++ K++A ++Q +R + F + ++++ + +Q+ +R QAR+ Y+ + + IQ YYR++V++ F A KL+S+ AA IQ +R ++ ++R+ +Q R E+ + +Q+ R Y R + R +A + +Q FR F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEQNSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAY--LKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLYRQIR----------AACVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVL--ASYQKIRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMR-ESCIKLQAFVRGYLVRKQMRLRRKAVISLQSYFRMRKAQQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 142.124 bits (357), Expect = 8.532e-33 Identity = 210/852 (24.65%), Postives = 401/852 (47.07%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFI 787
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ ++QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +QR ++ + ++ +VLQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR+ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+L++ + Q SA+ IQ+ ++ KAR+ L A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I+E Q I
Sbjct: 1844 YQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSAYRGWKVRKQIRRE---------HQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAILIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQ-------LLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQEQHQAAII 2630
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391791|sp|P62294.1|ASPM_PONPY (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 233.032 bits (593), Expect = 3.194e-61 Identity = 296/1228 (24.10%), Postives = 548/1228 (44.63%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-RKFIQRCCLQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++M R R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL +SA IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A Q+ +W +A +IQ +++ + Q L E+ +++A IQS +RM+ Y + Q + Q+ +H T +QA ++ K + +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F R ++ Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R R+ + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2302 FLRVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQAIFRMRRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKSAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQDQHQAAIIIQKNCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLAVQK----SVRTIQPAFRGMKVRQKLKNLSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAIWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRATCLIQAHYRGYKGRQVFLRQKSAALVIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQRKRFIQKYHSIKKIEHEGQECLSQQNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PNWVLRRDNMEEITNPLQAIQMVMDTLGI 3469 HSP 2 Score: 159.844 bits (403), Expect = 2.735e-38 Identity = 214/844 (25.36%), Postives = 385/844 (45.62%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQV-RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR---------------------------------KFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q +Q +W+ ++++LL K LE +N++A+LIQ +W+ + R +F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L S +IQ+ +R + +++ +L +NA + +Q + R + R AA IQ +R ++ ++R+ +Q R E+ + +Q+ R Y+ R + + +A + +Q FR F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q +R + + K ++R HQ A KIQS +RM AR++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1262 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQSAVINFLAKQRLRKRVNAALVVQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKQAKEENSAIVIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAAGVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHVRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHIL------TSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKVKQTRKQYLHLRA----AALFIQQCYRSKKIAAQKREEYMQMR-ESCIKLQAFVRGYRVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRIKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSTYRGWKVRK------QIRREHQAALKIQSAFRMAKARKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2059 HSP 3 Score: 142.51 bits (358), Expect = 6.549e-33 Identity = 209/854 (24.47%), Postives = 403/854 (47.19%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFI-QRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANEN 791
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ R+QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +Q ++ + ++ ++LQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + + LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR++ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+LQ+ + Q SA+ IQ+ ++ KAR+ L A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I++ Q I +N
Sbjct: 1838 YQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSTYRGWKVRKQIRRE---------HQAALKIQSAFRMAKARKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQHEKYLTILKAVKILQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAIWIQRKYRAHLYTKHHLQFLRVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQAIFRMRRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKSAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQ-------LLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQDQHQAAIIIQKN 2628 HSP 4 Score: 137.117 bits (344), Expect = 3.465e-31 Identity = 207/768 (26.95%), Postives = 356/768 (46.35%), Query Frame = 0
Query: 21 LVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQK---HLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAIL-IQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L RL +L RK + A IQ+ W+ + KL +LKR+Q +RE+ A+ ++QS A++R AA V+ K+W+ L Q+ L + + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ STL IQS FRKW +K + +K A I+QR++R + H R Q + N SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + E ++L++ A I +QS + R++Y+ LR +++ +Q+ R + R +Y + R S +Q A ++ + +MRL+ + +QS +RMR AR+ + LK Y AI+ IQ+++ QR FL++++ LQA + ++ + +A IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + R F+
Sbjct: 1250 LCARLLDL---RKEIRAARLIQTTWR----------KYKLKTDLKRHQ-------------EREK------AARIIQSAVINFLAKQRLRKRVNAALVVQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW------HLRKQAKEEN-SAIVIQSWYRMHKELRKYIYIRS---------CVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNL--CRQIRAAGVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQLQKYKKMKK----AAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSK-------KEFLSLKN-------------ATIKLQSIVKVKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQ------AFVRGYRVRKQMRLQRKAVISLQSYFRMRKARQYY----------LKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN------KRIKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVISLQSTYRGWKVRKQIRREHQAALKIQSAFRMAKARKQFR 1912
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391786|sp|P62289.1|ASPM_GORGO (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 233.032 bits (593), Expect = 3.224e-61 Identity = 294/1228 (23.94%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-----RK-------------FIQRCCLQR--CLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASAL----------------EEL----KNYSAILIQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A Q+ +W +A +IQ +++ + L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MHQ+AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F RK F+Q +R +R A+ + R W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ E ++ +A LIQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + ++H + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+ + +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2307 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARHLLREK------HKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHQAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMEVRQKLKNVSEEK-VAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKYAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNALRIQRAYKLYLAMKHANK------QVNSVICIQRWFRARLQEKRFIQKYHSVKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAHSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3474 HSP 2 Score: 160.614 bits (405), Expect = 1.694e-38 Identity = 208/839 (24.79%), Postives = 390/839 (46.48%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAF----QAERKLESL---------------AATTIQSAWRRNQV-RRERQRIIQTRN----------------------EAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R +F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++ ER + +A ++Q+ +R + L Q A A +IQ+ WR+ + ++ + I LQA V+ QR++++ K++A ++Q +R + F + + +++ + +Q+ +R QAR+ Y+ + + IQ YYR+HV++ F A KL+S+ AA IQ +R ++ ++R+ +Q R +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + ++++++ +Q A+R + + K ++R HQ KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ + +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1267 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLVIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKHAKEENSAIIIQSWYRMHKELQKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAY--LKGKIERTNYLQKRAAAIQLQAAFRRLKAHN--LCRQIRA--------ACVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVL--ASYQKTRSAVIVLQSAYRGMQARKMYVHILTSVIKIQSYYRAHVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAALISLQSAYRGWKVRK------QIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKA------WTAGRKQRMEYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2064 HSP 3 Score: 141.739 bits (356), Expect = 1.231e-32 Identity = 201/805 (24.97%), Postives = 380/805 (47.20%), Query Frame = 0
Query: 50 SRQELLRRLKLALELKRNQSATL-IQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFI 787
S Q R K+ +++R A L IQS ++ ++QF KTA++V+Q +F+ A R+ ++ ++ A ++ W+G ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G QR ++ + ++ ++LQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR+ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+LQ+ + Q SA+ IQ+ ++ KAR HL A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I+E Q I
Sbjct: 1879 SLQSAYRGWKVRKQIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKAWTAGRKQRMEYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAVFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKTQREKYLTILKAVKILQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRKQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAILIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKAR-------HLLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQEQHQAAII 2629 HSP 4 Score: 125.176 bits (313), Expect = 1.527e-27 Identity = 178/642 (27.73%), Postives = 308/642 (47.98%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWA------TKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER+ + IQ + A++R AA +IQ+ WR R + L + ++ N++A+ IQ YWR + +RR +L+ + + Q + A IQ WR +++ K Y+ ++ S +V+Q+ + W QR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + Q Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I +Q+H R QRQ+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS + R ++L LR + +Q +K AQ+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM KAR++Y + A IQ + RK F+++++A T +Q YRGY+VR K
Sbjct: 1259 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQEREKAARI------IQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLVIQSMFRKWKQRK-MQSQVKATVILQRAFREW-------HLRKHAKEENSAIIIQSWYRMHKELQKYIYIRSCVVIIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYVHILTSVIKIQSYYRAHVSKKEFL--------SLKN-ATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKARQYYLKMYK-------AIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIK 1821
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|215273935|sp|Q8IZT6.2|ASPM_HUMAN (RecName: Full=Abnormal spindle-like microcephaly-associated protein; AltName: Full=Abnormal spindle protein homolog; Short=Asp homolog) HSP 1 Score: 231.876 bits (590), Expect = 6.280e-61 Identity = 295/1228 (24.02%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQS ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L + +HL ++A IQ ++ R+M + + Q +A LIQ+ +R + F +H+++ IQ +R + A Q+ +W +A +IQ +++ + Q L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F + + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R + R R+ IQRA++ + +++ + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRSIP M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 160.999 bits (406), Expect = 1.310e-38 Identity = 213/836 (25.48%), Postives = 391/836 (46.77%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSR-------RSYLRFQTEAQEELE-------HCSATLIQAQWRVWI----QLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R ++ ++FQ ++ + +A +IQ +R +I L +Y++ R + IVLQ+ +G R+ + S +Q +R + ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G Q +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAY------VSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS--KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 147.902 bits (372), Expect = 1.703e-34 Identity = 209/872 (23.97%), Postives = 407/872 (46.67%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL----------AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEE--------QSEMRL--------RHQWATK-IQSLWRMRMARREFAQ---------IQASALE-------ELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V ++Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G H ++ +L+L ++A KIQ ++ R R+ F++ M + Y +A +IQ + R++ + R+ +L + + +Q+ FR ++ M+ AAT+IQ ++R YR ++ F L + +Q R W + ++FQ +L H S IQA +R + K M +A ++Q + + + RR+F S K++A ++QR +R + HHL++ ++ + +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + IQ FR F+QR C + L + + LR A + R + AA+LIQ+ +R + + + +SI++Q+ R + + R +Y R S VIQ A++ + L E QS R+ + QWATK IQ +R +++ Q +QA + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I +++ R +R ++Q M ++A IQS +RMH+A+ Y + + A IQ +++V RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1944 YIELRHAVLVLQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKE-YLNL-KKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYR------QQTYFNKLKKITKTVQQ--RYWAMKERNIQFQR--YNKLRH-SVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTK---HHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVR--KDIQN---MHRAATLIQSFYRMHRAKVDYE-------TKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIV 2770
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1111089551|ref|XP_019286036.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein isoform X3 [Panthera pardus]) HSP 1 Score: 263.848 bits (673), Expect = 8.009e-69 Identity = 292/1088 (26.84%), Postives = 517/1088 (47.52%), Query Frame = 0
Query: 33 KINQCATQIQSFWKMHRSRQELL-------------RRLKLALELKRNQ------SATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKW----SAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLK----AYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQA----RQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALV------IQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALR-----HEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDY------------------ERSR-----SSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRM-----------HKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMER---GRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
++ ++QS KM ++R++ L R +K+A LKR + S +Q+ + H+ R+Q + + A+V LQS+FR K R+ +L M +AA VI +++ ++ +++R + + R+ T +Q ++ ++ RQ Q+ + +A IQ+ +R +S+RK + ++ ST++IQ +R + + +F K A +Q ++R ++ R Q R Q+A +IQS +RM +++ + F+T +A +IQ R W K Y ++R +A++LQ+ KG I RRQ Q + A ++Q +R KW M ++A IQ +R ++ RQ YL+T+ A + IQ YRS R + K AA IQS +R + ++ R A L+ I+ A RQ + L L++ V+IQ FR R C+Q + ++ H+A+ R + + R+ AA+LIQ+ WR + R +Y+ K++ +Q R W R++Y ER+R +S +IQR WR L R+ + M RHQ A IQ+ +R R+ F + +++AL ++ Y I++ G +R K++ L+++ + LQAL + + ++R+ R R+ IQRA++ H ++++ K S I +Q +R H + R L + A + IQ++++ +++RKK +I +T IQ +RGY R K+D KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + ++ ++TL+++L +YR+K D I+TKT LL LL ++NR + + ++ +K R H ER +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 1679 RLKHATVKLQSIVKMKQTRKQYLHLRAATLFIQQWYRSIKVA-ALKREEYVQMRESCVKLQAFVRGHLVRKQMRSQRKAAVSLQSYFRMRKMRQHYLEMYKAAVVIQNYYRA--YKAQVSQRKNFLQVKRAVTCVQAAYRGYKVRQLI------KQQSI---AALKIQTAFRGYSKRKKYQYVLQSTIKIQRWYRTYRTVRDVRMQFLETKAAVISLQSAYRGWKV------RTQIRRELQAAVRIQSAFRMAQTQKRFRLFKT---------AALVIQQHLRAWSAGKKQRMEYTELRNAALMLQSTWKGKIVRRQIRKQHKCAVIIQSYYRMH------VQQKKWDIMKKAARLIQMYYRAYRIGRRQRQLYLKTKAAIVIIQSAYRSMRVRKKIKEYNK----AAVAIQSTYR---AYKAKKNYTTYRASAVLIQRWYRNIKIANRQRKEYLNLKK---TAVKIQAVFRGIRVRRCIQHMHTAATFIKAMFKMHQAKVR-YHKMRT-AAVLIQAAWRSYKAR-KYLCKVKAACKIQAWYRSWKARKEYLAILKAVKVIQGCFYTKLERTRFLNMRASTIIIQRKWRAM-LSGRIAHEHLMIKRHQAACLIQANFRRYKGRQVFLRQKSAALT-IQRY----IRARKAGKCERIKYVELKKSTVVLQALVRGWLVRKRISEQRTKIRLLHFTAAAYCHLSALRIQRAYKLHMVMKNA------KKQVNSVICVQRWFRTRLQQKRFAQKCHSVIKSQRELQEHMSQQNRAASVIQKAVRRFLLRKKKEKINNGITKIQALWRGYSWRK--KND------------------GTKIKAIRLSLQLVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAVSKIFV-LIRSCNRSVPCMEVIRYSVQVLLNVAKYEKTTAAVYH-VENCIDTLLDLLQMYREKPGDKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTARKHKMNTERILYTQKKNSSISIPFIPETPIRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 2683 HSP 2 Score: 164.081 bits (414), Expect = 4.930e-37 Identity = 221/860 (25.70%), Postives = 401/860 (46.63%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKR-----------------------NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRR----QFESQKRSARVLQRSWR----RFKFVQSLAHHL-------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRS---------------------------HVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y ++ +L ++ ++ A IQS S+Q L + + AL +++ N+SA++IQ +W+ + R+QF LK SV+LQS R A + + A I + W L +KH +R ++ S+ IQ ++ W+ + L+I A Q R++ SA +IQS +R E + ++HLR + IQ+ FR AQK + K A IQ+ +R + ++Q IQ FR + ++A QSYWRM RR RF + ++ +QAQ R+ QL+ YK+++ +A+++Q ++ I + ++ + + VLQ ++R R KF+ L + K+ R+ + ++Q+ +M Q R+ YL + A L IQ++YRS H+ R +++RK AA ++QS +R +R+ RQ ++ +AA+VIQ+ +R Y+ ++ QR + F+Q ++R ++ A + R + +S+AA+ IQ+ +RG+++R++Y + +S+I +Q+ R + RD + ++++V +Q A+R + + ++++R Q A +IQS +RM ++ F + +AL +IQ H R G QR ++ LR + LQ+ K I +R++ + A IIQ +R H + +K+ +M ++A IQ +R ++ R R L +A + + RSM+ VRKK +A IQ YR Y+ + + +
Sbjct: 1270 RAARLIQTTWRKY---KQKTDLKRHQERDKAARIIQSAVISFLSKQRLKKEINAALAIQKHWRRLLAQRKLLMLKKEKLEKVQNKSASVIQRYWRRYSTRKQFLKLKYYSVILQSRIRMIIAVTSYKRYRWATVTIQRHWLAYLRRKHDQQR--YEMLKSSSLIIQSVFRRWKQHKMQLQIKAAIILQRAFREWHVRKRAKEEKSAVVIQSWYRMQKELQKYIHLRSCVVIIQTRFRCLQAQKSYKRRKEAILTIQKFYRAHLKGKTERANYLQKRAAAIQLQAAFRGMKARNLRRQIRAACVFQSYWRM---RRDRFRFLNLKKITIK------LQAQVRMHQQLQKYKKIKKAALIIQIHLRASILAKRALASYQKTRSAVIVLQSAYRGMQARRKFIHILTSIIKIQSYYRAYISRKKFLRLKHATVKLQSIVKMKQTRKQYLHLRAATLFIQQWYRSIKVAALKREEYVQMRESCVKLQAFVRGHLVRKQMRSQRK----AAVSLQSYFR---MRKMRQHYLEMY-KAAVVIQNYYRAYKAQVS-----------QR--KNFLQ---VKRAVTCVQAAYRGYKVRQLIKQQSIAALKIQTAFRGYSKRKKYQYVLQSTIKIQRWYRTYRTVRDVRMQFLETKAAVISLQSAYRGWKV------RTQIRRELQAAVRIQSAFRMAQTQKRFRLFKTAAL---------VIQQHLRAWSAGKKQRMEYTELRNAALMLQSTWKGKIVRRQIRKQHKCAVIIQSYYRMH------VQQKKWDIMKKAARLIQMYYRAYRIGRRQRQLYLKTKAAIVIIQSAYRSMR---VRKKIKEYNKAAVAIQSTYRAYKAKKNYTT 2067
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1229163229|ref|XP_022094618.1| (abnormal spindle-like microcephaly-associated protein homolog [Acanthaster planci] >gi|1229163231|ref|XP_022094619.1| abnormal spindle-like microcephaly-associated protein homolog [Acanthaster planci] >gi|1229163233|ref|XP_022094620.1| abnormal spindle-like microcephaly-associated protein homolog [Acanthaster planci]) HSP 1 Score: 258.07 bits (658), Expect = 7.864e-67 Identity = 309/1121 (27.56%), Postives = 520/1121 (46.39%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSAT------------------LIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQR----RQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNR----------LCLERRIQACV---------RIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMR---ESARIIQRAWRRHRLIR--------HLAELQKYKVMTQ---SAITIQSLWRMHKARRHYRHLTHLAASAEMAGA-TIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQV---RTAFKSDC------------KIKQTALLP-----DFPINEEL-SKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLLA-SSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMER----------------GRRRNNYLPNSF-----------RPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLALK 1018
RS ++Q +R Y QR + L +R + IQS +MH++R++ + ++A+ ++R AT +Q++ + H+ R+ L A+ +Q + + R R+L MK AA V+ K+W+ + +++ + + ++AT +Q ++ GR+ A+E +A LIQS +R H + + +L+ + + IQ+ +R + + + A IQ+ +R + + R F L +SA KIQ+ +R +R Y + +A IQA +R Q K + ++ SA+VLQ + + + R R + Q+ +A Q ++R + ++ + RM Q+AT IQ+ +R + +L + + +Q YR+H+ A FQA+R AAT IQ+ +R + ER R I ++ AA+VIQS R + R L L+RR +A V IQRG IQ QR R Q W AAI IQS+WR QR+RY+ L+ + + + RRD+ R + Q +R ALI +Q + + IQS R R AR +I+A A+ IQS +RG Q+ ++ +R+ + LQA + IA++ + +MR ++A IQR +R + + LA+L+++ + + SAI IQ +RM+K + AA A+M IQR M+ + R F+++RR++ +Q+ R +Q R A + K+K AL + SKKI R + AN+ TE+KKL NRTA ALD L + R ++ LL L LDV +R SA CC++++ + V ++ L+R CNRS+P M++I +++ +NL KY P+ + E + V +++++ +YR+K I+ K LL LA R K IL+ P N ++L+ + R H+ + +R G +++L SF P+P K + P+ + P W + +R DP A V+ L LK
Sbjct: 2262 RSARLMQSYFRMY--CQRRQYLNWKRT----SVTIQSAVRMHQARRKYTKLKQVAIIIQRRYRATQLARWTYLRYHIQRGACITLQAYARGHLARQHIHRLHAAATTIQKNHAAYQTRTRYLKMKGAAKVLQKYWRATRLARE--QKLMFTSLRKAATTLQSVYRGNAGRKI-------ARE---HRAARLIQSVYRMHVAFQKYSNLKAAAITIQALYRMRRDRNCYLRLVAATVTIQQFFRGHLLTRA--SRNAFLLARRSAVKIQAAYRGLAQQRGY---------NILKQAAARIQALYRGKRQRKEFLTLKWSAVVLQERYRAHVLRDQAFRAYNIQRGAAITAQAAYRAYTARKN------YTRMKQAATTIQSVYRGHRQSTDFLLMRRSAAVLQMRYRAHLLMREAVQTFQAKR----WAATVIQAFYRAHA---ERCRFINCKS-AAIVIQSTCRGRKQREEYQAIRRATLVLQRRYRAHVLQTETTRNYHIQRGAVITIQ--AYQRG-------RLARQYVKWIR----AAIKIQSYWRMVIQRRRYLALQNAVNKIGASFKARAARRDFLSLRHAAVTFQTRYR--ALIMTQAQQRKYDRICRAIITIQSFIRGRQARELTKRIRA----------AVKIQSAYRGYTQQRRYQSVRKCVLLLQARTRGMIARQMVSTMRKWQQAAVCIQRHFRGYAARKILEAQRQARLAQLERFSSVARFHLSAIRIQHRYRMYKMCQ--------AAKAKMQSIRIIQRWMRATLQRLHFLKLRRSIIALQRRVRQHQALRQRAAVRIQAQARVWLARQYVRKMKAAALTVQSAWRGLHVRRSCKSKKIAAARARCIKANKAVTEEKKLCNRTASALDYLLQYRQMSGLLEALISLDVVSRLSAACCERLV--EGQAVPVIFTLIRSCNRSLPCMEVIKYSVNILLNLTKYPPTAHAVFEEPESV-SIILDLMQMYREKGTPIFCKVCMLLGTLAQDPRRAKIILSAPKNKERLVGIKRLTERKHSLEAKRAQAKARSLNNSCLSNTGSCNSSFLGASFLSTSALNASSLMPAPTPRKQQRPQRWVEPEWVLGRSKMREIADPLEACYFVMEALNLK 3303 HSP 2 Score: 157.532 bits (397), Expect = 4.762e-35 Identity = 209/798 (26.19%), Postives = 365/798 (45.74%), Query Frame = 0
Query: 34 INQCATQIQSFWKMHRSRQELL--RRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKW----SAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVW----IQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMW----QARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRI------IQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERI----ALRHEAQERAWTESRSLAAILIQSHWRGW----TQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSA------------------ILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLA----ELQKYKVMTQSAI----------------TIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQV 749
+N A IQS WKMHR+++ L +R L ++ L+ + LIQS +A + + +F L+ + LQS+ R A + F ++ AA VI + ++ + + H ER +L R AT W RG ++A Q + +A IQS ++++ ER+ F +R ++ +Q R + S + +K AA IIQ S+R L R F+ ++A KIQ+ RM +R +LR + +A +IQA++R L Y+ R + I LQA V+G + RRQ +A ++Q +++ + +K +H + +Q R + AR YL+ +++ + IQ YR VAR F ++++ AA IQS R +Q R + IQ R A + Q+ QYQ +C AC+ +Q G R + R ++R + + R +A + + + R+ AA+++Q +WR R+ ++ LRK++ ++Q RG + RR + RS+ RVIQ +R + + + Q + A +IQS RM+ AR + ++ +AL Y A I +Q+ RG + R + +L +++Q ++ + Q + +R +A ++Q WR RL R + L+ V+ QSA +QS +RM+ RR Y + + TIQ +++M R+K+ ++++ +IQ+ YR Q+
Sbjct: 1582 LNGSAVIIQSVWKMHRAQKGYLEMQRATLCIQKYTRSYLIGKAARCHYLQLRAAMVLIQSRCRAAMAQRKFRHLRVCCIALQSYVRMYIATKHFRAIQGAAVVIQQRFRAKVSRDHQMERYNL---QRKATIALQAWA--RG------VLARRQIAAQNDAAIQIQSTYKAYRERQNFKIVRSASACLQKYVRAYLIGKSVHTDYLKLKTAAVIIQSSYRG------LLTRRNFQTQKRAALKIQAVVRMHQARSRFLRLRR---------AALIIQARYRAQRLAQETLIQYQIARGACITLQAGVRGHLVRRQMRKLHAAAVLIQSTYK------AHVEQQMYKMLHSATICLQRHARAYLIGKSARIDYLKMKSSAIVIQSSYRGLVARRTFNSQKQ----AAVKIQSVVRMHQARNHYMELRWATTAIQNRYRAQKLAQATSLQYQ--ICRG----ACITLQAGIRGLLVRQQIKRLDKAAVLIQKSYRAQAAQAKYQKMRN-AALVLQEYWRATRLAREVREEFMSLRKAAGVLQSAFRGKLGRRIAKEHRSA-RVIQSYFRMHLMWQCYQRQ------RRAAVRIQSAARMQQARSRYGALRCAALIVQTRYRARKASEVVCRQYQVVRGACITLQAATRGFMVRQQIRKLHAAAVQIQKSYRSHLMQTQYQKLRGAALVLQMYWRATRLSRQVQRDFLALKNAAVVLQSAYRGQVGRRISSRHRSARLMQSYFRMYCQRRQYLNWKRTSV-------TIQSAVRMHQARRKYTKLKQVAIIIQRRYRATQL 2322 HSP 3 Score: 150.214 bits (378), Expect = 8.614e-33 Identity = 197/779 (25.29%), Postives = 351/779 (45.06%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQ-----------------------VKGWI----QRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ--NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEA----QERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
Y L+ + ++Q WR L ++++ L + A +QS + R ++ RR+ R++SA L+QS+++ + QR Q+ K SV +QS R +ARR++ +K+ A +I + ++ + R H+ RG + +Q+ R H R+ L + IQ + + R+ MK AA ++Q+ WR R + +++ F L ++AT +QS +R R+ EH +A LIQ+ +R+ + + Y ++ +AI +QA +G + R F +RSA +Q ++R LA + + Q+A RIQ +R + R+ +L + + + +Q+ YR+HV R AF+A ++ AA T Q+A+R R+ R+ Q AA IQS +R ++ L RR A ++++ +R + L EA Q + W AA +IQ+ +R +R R+I + ++I++Q RG R +Y+ R + V+QR +R A + + E ++ IQ+ R R+AR+ I+A AI IQS+WR +QR ++L L+ ++ A KA A+R +S+R +A Q +R LI A+ +KY + ++ ITIQS R +AR + + A IQ + + + ++++ +R+ V ++Q RG
Sbjct: 2208 YQKLRGAALVLQMYWRATRLSRQVQRDFLA--LKNAAVVLQSAY-----RGQVGRRIS-----SRHRSARLMQSYFRMYCQRRQYLNWKRTSVTIQSAVRMHQARRKYTKLKQVAIIIQRRYRATQLARWTYLRYHIQ----------------RG------------------ACITLQAYARGHLARQHIHRLHAAATTIQKNHAAYQTRTRYLKMKGAAKVLQKYWRATRLAR--EQKLMFTSLRKAATTLQSVYRGNAGRKI----------AREHRAARLIQSVYRMHVAFQKYSNLKAAAITIQALYRMRRDRNCYLRLVAATVTIQQFFRGHLLTRASRNAFLLARRSAVKIQAAYR------GLAQQRGYNILKQAAARIQALYRGKRQRKEFLTLKWSAVVLQERYRAHVLRDQAFRAY-NIQRGAAITAQAAYRAYTARKNYTRMKQ----AATTIQSVYRGHRQSTDFLLMRRSAAVLQMR--YRAHL--------------LMREAVQTFQAKRW------AATVIQAFYRAHAERCRFINCKSAAIVIQSTCRGRKQREEYQAIRRATLVLQRRYR--AHVLQTETTRNYHIQRGAVITIQAYQRGRLARQYVKWIRA----------AIKIQSYWRMVIQRRRYLALQNAVNKIGASFKARAARRDFLSLRHAAVTFQTRYR--ALIMTQAQQRKYDRICRAIITIQSFIRGRQARELTKRIR--------AAVKIQSAYRGYTQQRRYQSVRKCVLLLQARTRG 2873 HSP 4 Score: 142.51 bits (358), Expect = 1.991e-30 Identity = 212/845 (25.09%), Postives = 389/845 (46.04%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELL--RRLKLALELKR-----------NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFR-QTKAR---RRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFL---RIMADAQEELRQY---------------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQ----KRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQA--ERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNR----------LCLERRIQA-----------------CVRIQRGFRKFIQRCCLQ-------------------------RCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAEL--QKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
YL ++ + IQ WR + + E + + + A +QSF++ +R+ + RR+ A L R ++ +IQ ++ + Q+ ++ L+ A++VLQ R Q K R R + M+ A + W +G L R L+++N SA IQ WKM R ++ +L R Q+ R Y + LIQS+ R+ ++ F HLR + +QS R + A K F +++ AA +IQ+ +R H ER + L ++ +Q++ R ++RR Q AQ + +A IQ+ ++ + + + +K +R ++ LQ V+ ++ + + K +A ++Q S+R L ++ ++A +IQ RM QAR +LR + A L IQ YR+ RLA + + ++ A T+Q+ R + VRR+ +++ + AA++IQS ++ + + +CL+R +A + IQ +R + R R + I R+ AQ+ A S A I +Q+ RG RQ+ L K+++++QK R + Y++ R++ V+Q WR L + + E+ M LR + A +QS +R ++ RR + + SA +IQS++R + + R RR +R+Q+ A+ A+ R ++R +A I+Q +R R +E+ ++Y+V+ + IT+Q+ R R+ R L H AA IQ+S + +++ ++ ++R A V+Q ++R
Sbjct: 1434 YLQMKSAASAIQMRWRSTLHARSVREEYVS--LRRAAVVVQSFYRGMVARRYAMYVRRVVKAQSLARCFLQRQRFLLQKRACIVIQKSFRGYTQKNRYELLRGATLVLQRRLRAQEKGRVQLREYKVMRGAVITLQAWARGIL------TRRWLAILNGSAVIIQSVWKMHRAQKGYLEMQRATLCIQKYTRSYLIGKAARCHYLQLRAAMVLIQSRCRAAMAQRKFRHLRVCCIALQSYVRMYIATKHFRAIQGAAVVIQQRFRAKVSRDHQMER--YNLQRKATIALQAWARGVLARR-----QIAAQND----AAIQIQSTYKAYRERQNFKIVRSASACLQKYVRAYLIGKSVHTDYLKLKTAAVIIQSSYR------GLLTRRNFQTQKRAALKIQAVVRMHQARSRFLRLRRAALIIQARYRAQ--RLAQETLIQYQIARGACITLQAGVRGHLVRRQMRKL----HAAAVLIQSTYKAHVEQQMYKMLHSATICLQRHARAYLIGKSARIDYLKMKSSAIVIQSSYRGLVARRTFNSQKQAAVKIQSVVRMHQARNHYMELRWATTAIQNRYRAQKLAQATSLQYQICRGACITLQAGIRGLLVRQQIKRLDKAAVLIQKSYRAQAAQAKYQKMRNAALVLQEYWRATRLAREVREEF-MSLR-KAAGVLQSAFRGKLGRRIAKE----------HRSARVIQSYFRMHLMWQCYQRQRRAAVRIQSAARMQQARSRYGALRCAALIVQTRYR----ARKASEVVCRQYQVVRGACITLQAATRGFMVRQQIRKL-HAAA------VQIQKSYRSHLMQTQYQKLRGAALVLQMYWRA 2224 HSP 5 Score: 139.043 bits (349), Expect = 2.500e-29 Identity = 201/793 (25.35%), Postives = 355/793 (44.77%), Query Frame = 0
Query: 63 ELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ--AFLRIMADAQEELRQY-----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFR---KWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-----------TEAQEELEHC-------SATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLK--------------WKR----------MHQSATRIQTQWRMWQARQSY--LRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR--KFIQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQI-----------------QASALE-ELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAE----LQKYKVMTQSAI----------------TIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
L+R+ TL Q+ ++ + R + ++A V LQ+ R R+L MK AA I W+ L + + E ++SL R+A +Q +++ R+ ++R + AQ R + + +IQ +R ++++ + LR +TL +Q R K Q R + A I ++W + + R +LN SA IQS W+M +++ YL Q + + C + LIQ++ R + + ++ +R I LQ+ V+ +I + F + + +A V+Q +RF+ S H ++ W R + +A +IQ+ ++ ++ RQ++ +R+ +ACL QKY R+++ + + AA IQS++R RR QT+ AAL IQ+ R +Q R R +A + IQ +R + Q +Q ++ + +A R R + AA+LIQS ++ ++Q Y L ++I +Q+ R +++ R DY + +SS VIQ ++R L+ R S+ Q A KIQS+ RM AR + ++ QA++L+ ++ + I +Q+ RG + R + RL + + +Q +A AQ + MR +A ++Q WR RL R + E L+K + QSA IQS +RMH + Y+ A IQ + +M R ++ +R A ++Q YR
Sbjct: 1389 NLQRSACLTL-QAAFRGYACRCGYRKKRSAVVALQARIRAHLQCVRYLQMKSAASAIQMRWRSTLHARSVREE-YVSL-RRAAVVVQSFYRGMVARRYAMYVRRVVKAQSLARCFLQRQRFLLQKRACIVIQKSFRGYTQKNRYELLRGATLVLQRRLRAQEKGRVQLREYKVMRGAVITLQAW-----ARGILTRRWLAILNGSAVIIQSVWKMHRAQKGYLEMQRATLCIQKYTRSYLIGKAARCHYLQLRAAMVLIQSRCRAAMAQRKFRHLRVCCIALQSYVRMYIATKHFRAIQGAAVVIQ---QRFRAKVSRDHQMERYNLQRKATIALQAWARGVLARRQIAAQNDAAIQIQSTYKAYRERQNFKIVRSASACL--QKYVRAYLIGKSVHTDYLKLKTAAVIIQSSYRGLLTRRN----FQTQKRAALKIQAVVRMHQARSRFLRLRRAALIIQARYRAQRLAQETLIQYQIARGACITLQAGVRGHLVRRQMRKLHAAAVLIQSTYKAHVEQQMYKMLHSATICLQRHARAYLIGKSARIDYLKMKSSAIVIQSSYR--GLVARRTFNSQ----KQAAVKIQSVVRMHQARNHYMELRWATTAIQNRYRAQKLAQATSLQYQICRGACITLQAGIRGLLVRQQIKRLDKAAVLIQKSYRAQAAQAKYQKMRNAALVLQEYWRATRLAREVREEFMSLRKAAGVLQSAFRGKLGRRIAKEHRSARVIQSYFRMHLMWQCYQR-------QRRAAVRIQSAARMQQARSRYGALRCAALIVQTRYRA 2151 HSP 6 Score: 120.168 bits (300), Expect = 1.549e-23 Identity = 227/900 (25.22%), Postives = 385/900 (42.78%), Query Frame = 0
Query: 21 LVQRLEELILERKINQCATQIQSFWKMHRSRQ---------------------------------------------------ELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKT-ASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHL---NERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELR--QYSATL-IQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRR--SYLRFQTEAQEELEHC------------SATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKW-KRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFI------QRCCLQRCLSERIALRHEAQE---RAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASAL-------------EELKNY----------------------------SAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACI----AQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHL-------------THLAASAEM-------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
L RL +L E + A IQ WK HR RQ E LR+ +LA L+R+++A +Q+H + + R KT ++++QS R+ AR+ +L + W Q + ER M +A +Q ++ R + Q L Q SA L +Q+ +R ++ R + R + + +Q+ R R+ MK AA+ IQ WR + + E ++ L ++A +QS++R ++RR Y+R +AQ L C + +IQ +R + Q Y+ +R + +VLQ AQ KG +Q R+++ + + LQ +W R + +W ++ SA IQ+ W+M +A++ YL Q A L IQKY RS++ A + A IQS R +R+ + + + +QS R Y A V IQ+ FR + +R LQR IAL+ A+ R +++ AAI IQS ++ + +RQ + +R +S +QK VR +++ + DY + +++ +IQ ++R L+ R Q++ R A KIQ++ RM AR F +++ +AL E L Y +A+LIQS ++ V++ + L I LQ A+A + A+ + M+ SA +IQ ++ R L + + Q+A+ IQS+ RMH+AR HY L LA + + A T+Q ++ +VR++ R+ +A +IQK YR + ++ K++ AL+
Sbjct: 1205 LCARLLDLRTE---TRAARTIQVVWKAHRLRQLVKQRQAQEAAAKIIQCAVHSFLTRRRHQRLLGSIVKLQAMRRRVIACRQAEALRQAQLA--LRRHRAAISLQAHVRGFLARRHH--KKTLKAIIIQSALRRYIARKTYLQSR---------WAVITLQAAVRCHQERCCFVQMREAAVILQQRFRAKR--------IGSKQRALYNLQRSACLTLQAAFRGYACRCGYRKKRSAVVALQARIRAHLQCVRYLQMKSAASAIQMRWRSTLHARSVRE--EYVSLRRAAVVVQSFYRGMVARRYAMYVRRVVKAQ-SLARCFLQRQRFLLQKRACIVIQKSFRGYTQKNRYELLRGATLVLQRRLRAQEKGRVQLREYKVMRGAVITLQ-AWARGILTR------RWLAILNGSAVIIQSVWKMHRAQKGYLEMQRATLCIQKYTRSYLIGKAARCHYLQLRAAMVLIQSRCRAAMAQRKFRHL----RVCCIALQSYVRMYIATKHFRAIQGAAVVIQQRFRAKVSRDHQMERYNLQR--KATIALQAWARGVLARRQIAAQNDAAIQIQSTYKAYRERQNFKIVRSASACLQKYVRAYLIGKSVHTDYLKLKTAAVIIQSSYR--GLLTRRNFQTQKR----AALKIQAVVRMHQARSRFLRLRRAALIIQARYRAQRLAQETLIQYQIARGACITLQAGVRGHLVRRQMRKLHAAAVLIQSTYKAHVEQQMYKMLHSATICLQRHARAYLIGKSARIDYLKMKSSAIVIQSSY------RGLVARRTFNSQKQAAVKIQSVVRMHQARNHYMELRWATTAIQNRYRAQKLAQATSLQYQICRGACITLQAGIRGLLVRQQIKRLDKAAVLIQKSYRAQAAQAKYQ---KMRNAALV 2049
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|524876917|ref|XP_005095167.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein homolog isoform X2 [Aplysia californica]) HSP 1 Score: 258.07 bits (658), Expect = 8.145e-67 Identity = 308/1184 (26.01%), Postives = 533/1184 (45.02%), Query Frame = 0
Query: 33 KINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF----------QKHLNE------RIHLSLMN-----RSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSH----SERKAF-----------------LHLRH-----STLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI-QACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSE---------------MRLRHQWA------TKIQSLWRMRMARREFAQIQASALE---ELKNY-------------------------------------SAILIQSHWRGCVQRGKFLRLRRTCIRLQAL----------------------------------AKACIAQR--------RLVSMRESARIIQRAWRRH----RLIRHLAE-----------LQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIR---RAVTVIQKHYRGYQVRTAF------------------KSDCKIKQTALLPDFPIN-EELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERGRRRNNYLP-----NSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLALKP 1019
KI +QS W++ R+R+ L R+L+ E K N+SA IQS+W+ R F + A+V++Q ++R RR+ + AA VI W++ C+ +KHL E R +L+ N ++A IQ +++ +R R FL + + ++ +IQ +R++ R+ + L LRH S ++IQ+ FR + ++ + + AA +IQ +R + +Q ER +F Q+A IQS +R + + Y T SA IQA R K + ++ +A++LQ A++ G + R F S + S ++QR +R K + L L +R +A +IQ+ +R W RQ YL + AC+ Q+ YR+ + + E K +A IQ WRR + + + +S +Q RL E+R+ Q +R + +QRC R + ++ L +++ +E R AA+++Q +R + R +Y R + +Q+ +RG+ VRRD+ER R +IQR WR L K ++ E +R R ++A TKIQ+ RM + + F ++ + + L++Y S + +QSHWR C QR +F R + L+AL ACI QR RL ++A IIQ+A+R+H R ++H + +Q+ + +SA+ IQS R + A R ++ + + T+Q S++ W+ R++ +R RA+ +Q RGY VR K+ KI+ AL + + S+++ + R+++ ++ ATE+K LG+R + ALD L R +D+A++L + L+V+TR S CC++++ + V L L CNRSIPHM+II +D +NLAKY+ + V++E ++ + T++E+++IYR+K I+ K LL +L R ++++ LN L+E + H L ++++ R SF + A P + + P W + +D + DP + V++ L + P
Sbjct: 2529 KIKGSVITLQSAWRVVRARR-LFRKLR---EEKENKSALCIQSNWRMFQARHSFIRQRQAAVLMQCYWRGFLTRRQLEKSQEAAMVIQCWYRACVAARHQRLEFIEKKHLAELVQKMWRGYLARRNYQRERQAAIVIQAHFRCFRRRLKFLAL---------RLASVIIQRGYRNYRLGKQTRQEYIAITQAACTLQRWYRKCLELRHAQQISSAIKIQAAFRAYKTRQMVTTKRNAALVIQMKFRAH--LQMREERRKFLEQKQAAVTIQSCFRGYREQVMYKNILT---------SAIRIQALERKRQDRKRFLALKQAAVILQRRYRAKMLGLVFREAFLSIRSSVIIIQRFYRAVKVGEQLKELLDTQRA--AAIKIQSTYRGWSLRQDYLMLRAACVCCQRRYRAVQLGRSVRQEMKHRCVATRVIQREWRR-YLCVREAKRELEERREEVRRESQRQQEAERLAEEQRLMQEKAEDERKVFE-MQRCQAARVIQKQFVL---YRQKLCSERREKAAVMVQKCFRAYLVRCKYQETRNKLLFLQRLIRGFAVRRDFERQRLVAVLIQRWWRATLLAKHCRQEFESSRDAAVRIQTMYRMIRQRREYALSLQRVTKIQACVRMHVEHKRFIHVKCATIAIQRSLRSYLAMRRDRQQFLAAKHSAIKIQCEIRKWLACRRHKQEASVVALQSHWRMCQQRKEFQDAREAAMTLRALWESSQDNKQQQEHAARSIQLLFRNYMNKKLCLEHTAACIIQRAFRTFHQGRLQVKADAASIIQKAFRKHLAHKRQVQHKSAEAIQLAFRQHLIQRQAIKNESAVVIQSQVRRYLACRRFQAILG-------SVVTLQASVRGWLARQRAEELRKEQRALVFLQAQVRGYLVRKKVLPVLQARLDAIQEERKQRKASTKIQ--ALWRGYKVRRNSRSRRLIQARKRISELSQEATEEKTLGSRMSSALDYLLRDKDVAYILEAMMHLEVSTRLSPVCCERMIEVD--AVPALYRLAASCNRSIPHMEIIKHTVDTLLNLAKYDKTVAVVME-PEESISTIMELMLIYREKG-PIFYKCCMLLGILGLDPRRRQVI---LNQAHLIERLQSIHSLTLRKLKVSRTHKATQAKMAAMKSFNCTMPVATPTK-RRRIRPQWVLAKDTMHEFDDPLTSISFVMDVLHIGP 3664 HSP 2 Score: 169.859 bits (429), Expect = 7.556e-39 Identity = 204/774 (26.36%), Postives = 367/774 (47.42%), Query Frame = 0
Query: 12 IQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKT-----ASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLR-----HSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLL-----NQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQM-----RCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLE-SLAATTIQSAWRRNQV--RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWR----GWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCK 758
+Q +WRR+ + LE L ER +N+ A IQ F + R+ L Q+A IQ W+ + ++ L+T A+ V+Q H R RR ++ +A ++ K W+ + + E + +A +Q + R+ FLR+ + +A +Q+QWR ++ F+ LR H+ + IQ F ++ A+K +++ AA +IQ+ WR R++ R L +++A +Q + R ++ R++ R Q AQ+ IQ WRV + + ++ + + I++Q +G QR+ F K S LQ +WR + + L L+ ++ ++SA IQ+ WRM+QAR S++R + A + +Q Y+R + R R+LE S A + W R V R +R I+ ++ A LV Q WR Y R +R QA + IQ FR C +R L + +ALR LA+++IQ +R G RQ YI + +++ +Q+ R + R ++ S+++ IQ A+R + + + + L Q K ++ +MR RR+F + + +A+ IQS +RG ++ + + + IR+QAL + ++R ++++++A I+QR +R L L + + + S I IQ R ++A + L L + A IQ + + W +R+ ++ +R A Q+ YR Q+ + + + K
Sbjct: 2231 VQSAWRRHQAKKSLEMLKKER-VNKSAVVIQKFMRGRLCRKGFL---------TSKQAAVTIQKQWRMKLAQKFLVCLRTQKKTMAATVIQKHVRGRLCRREIEGLRGSALILQKLWRA-KKAREVVESLRAERQKEAAVLVQSVVRCASDRRKFLRL---------KRAAVCVQTQWRCVLAQREFMRLRLERQTHAAVVIQKNFHRFKAKKELYALRCAAVVIQKLWRAR------QARLELRKLRGQQKDRAALILQKHARGFLCRKNLQRSQMAAQK---------IQGLWRVCLARRELLRLRDQRRKSATIIIQKMFRGLQQRQAFAKIKGSVITLQSAWRVVR-ARRLFRKLREEKENKSALCIQSNWRMFQARHSFIRQRQAAVLMQCYWRGFLTR------RQLEKSQEAAMVIQCWYRACVAARHQRLEFIEKKHLAELV-QKMWRGYLARRNYQRERQAAIVIQAHFR------CFRRRL-KFLALR-------------LASVIIQRGYRNYRLGKQTRQEYIAITQAACTLQRWYRKCLELRHAQQISSAIK-IQAAFRAYKTRQMVTTKRNAALVIQM--KFRAHLQMREERRKFLE---------QKQAAVTIQSCFRGYREQVMYKNILTSAIRIQALERKRQDRKRFLALKQAAVILQRRYRAKML--GLVFREAFLSIRSSVIIIQ---RFYRAVKVGEQLKELLDTQRAAAIKIQSTYRGWSLRQDYLMLRAACVCCQRRYRAVQLGRSVRQEMK 2924 HSP 3 Score: 162.54 bits (410), Expect = 1.445e-36 Identity = 235/862 (27.26%), Postives = 398/862 (46.17%), Query Frame = 0
Query: 5 LQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKT-----ASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWK-------------------GCLFQKHLNE---RIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSAT-LIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKW-----AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA--------------QEELEHCS----ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKF-----------VQSLAHHLKWKR---------MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERK--LE-SLAATTIQSAWR--RNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR-KFIQRCCLQRCLSERI----------ALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALI------------------------KRL-EEQSEMRLRHQWATKIQSLWRMRMAR---REFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
L+ S I+Q+ WR + +E L ER+ + A +QS + R++ LR LKR +A +Q+ W+ + + +F L+ A+VV+Q +F + KA++ ++ AA VI K W+ + QKH R +L +A KIQG W++ R+ LR+ ++ SAT +IQ +R +R+AF ++ S + +QS +R A++ F ++ +A IQ +WR + Q H I+ R Q+A +Q YWR +++RR + Q A + LE A L+Q WR ++ + Y++ R +AIV+QA + + +R +F + + ++ ++QR +R ++ Q+ +W R SA +IQ +R ++ RQ +NA L IQ +R+H L + ER+ LE AA TIQS +R R QV + + +A+ IQ+ R+ Q+R QA V +QR +R K + + LS R A++ Q + +++ AAI IQS +RGW+ RQ Y+ LR + + Q++ R G VR++ + + RVIQR WRR+ + +RL EEQ M+ + + K+ + R + AR ++F + E + +A+++Q +R + R K+ R + LQ L + +R R A +IQR WR L +H Q+++ +A+ IQ+++RM + RR Y A S + IQ ++M V K+FI ++ A IQ+ R Y
Sbjct: 2326 LRGSALILQKLWRAKKAREVVESLRAERQ-KEAAVLVQSVVRCASDRRKFLR-------LKR--AAVCVQTQWRCVLAQREFMRLRLERQTHAAVVIQKNFHRFKAKKELYALRCAAVVIQKLWRARQARLELRKLRGQQKDRAALILQKHARGFLCRKNLQRSQMAAQKIQGLWRVCLARRELLRLRDQRRK-----SATIIIQKMFRGLQQRQAFAKIKGSVITLQSAWRVVRARRLFRKLREEKENKSALCIQSNWRMF---QARHSFIRQR---QAAVLMQCYWRGFLTRRQLEKSQEAAMVIQCWYRACVAARHQRLEFIEKKHLAELVQKMWRGYLARRNYQRERQAAIVIQAHFRCFRRRLKFLALRLASVIIQRGYRNYRLGKQTRQEYIAITQAACTLQRWYRKCLELRHAQQISSAIKIQAAFRAYKTRQMVTTKRNAALVIQMKFRAH---LQMREERRKFLEQKQAAVTIQSCFRGYREQV------MYKNILTSAIRIQALERKRQDRKRFLALKQAAVILQRRYRAKMLGLVFREAFLSIRSSVIIIQRFYRAVKVGEQLKELLDTQRAAAIKIQSTYRGWSLRQDYLMLRAACVCCQRRYRAVQLGRSVRQEMKHRCVATRVIQREWRRYLCVREAKRELEERREEVRRESQRQQEAERLAEEQRLMQEKAEDERKVFEMQRCQAARVIQKQFVLYRQKLCSERREKAAVMVQKCFRAYLVRCKYQETRNKLLFLQRLIRGFAVRRDFERQRLVAVLIQRWWRATLLAKHCR--QEFESSRDAAVRIQTMYRMIRQRREY------ALSLQRV-TKIQACVRMHVEHKRFIHVKCATIAIQRSLRSY 3148 HSP 4 Score: 134.035 bits (336), Expect = 8.084e-28 Identity = 178/639 (27.86%), Postives = 293/639 (45.85%), Query Frame = 0
Query: 173 RQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSW-------RHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWR---VWIQLKAYKQMRC--SAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR---LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAW------RQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRK--------SSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWR------------------RFALIKRL-----EEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQ------RAWRRHRL----IRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQV 749
R +A +Q WR K HLR L RK S AAT IQR+W R + + +R+ + + ++AT +Q + R RR ++R + +A +Q+ WR L+ K+ R SA+V+Q ++G + R+ F + K++A +Q+ W R K Q L+ ++ +AT IQ R R+ + + L +QK +R+ AR + +AER+ E AA +QS R RR+ R+ AA+ +Q+ W R++ RL LER+ A V IQ+ F +F + E ALR AA++IQ WR RQ + LRK +++++QK RG++ R++ +RS+ + + IQ WR +I+++ + Q+ +++ T +QS WR+ ARR F +++ EE +N SA+ IQS+WR R F+R R+ + +Q + + +R+L +E+A +IQ A R RL +HLAEL +Q +WR + ARR+Y+ A IQ + + R KF+ +R A +IQ+ YR Y++
Sbjct: 2129 RALAAVRLQCAWRRFRACKMLAHLRQEKLAKAELERKAS----------AATTIQRTWRASMIRRREAKVKEMEKKRVIYEMQQKAATTVQRHVRGLQCRREFVRSKQ---------AAVCVQSAWRRHQAKKSLEMLKKERVNKSAVVIQKFMRGRLCRKGFLTSKQAAVTIQKQW-RMKLAQKFLVCLRTQKKTMAATVIQKHVRGRLCRREIEGLRGSALILQKLWRAKKAREVVESLRAERQKE--AAVLVQSVVRCASDRRKFLRL----KRAAVCVQTQWRCVLAQREFM-RLRLERQTHAAVVIQKNFHRF-------KAKKELYALR-------------CAAVVIQKLWRA---RQARLELRKLRGQQKDRAALILQKHARGFLCRKNLQRSQMAAQKIQGLWRVCLARRELLRLRDQRRKSATIIIQKMFRGLQQRQAFAKIKGSVIT-LQSAWRVVRARRLFRKLR----EEKENKSALCIQSNWRMFQARHSFIRQRQAAVLMQCYWRGFLTRRQLEKSQEAAMVIQCWYRACVAARHQRLEFIEKKHLAEL------------VQKMWRGYLARRNYQR-------ERQAAIVIQAHFRCFRRRLKFLALRLASVIIQRGYRNYRL 2693 HSP 5 Score: 106.686 bits (265), Expect = 2.222e-19 Identity = 137/487 (28.13%), Postives = 224/487 (46.00%), Query Frame = 0
Query: 333 LQRSWRRFKFVQSLAH-------HLKWKRMHQSATRIQTQWR-------------MWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTR-NEAALVIQSAWRQYQNRLCLERRI---QACVRIQRGFR-KFIQR--CCL---QRCLSERIALRH------------------------------EAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDY-----ERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKAC----IAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR 750
LQ +WRRF+ + LAH + +R +AT IQ WR M + R Y Q A +Q++ R R F ++ AA +QSAWRR+Q ++ + + + R N++A+VIQ R RLC + + QA V IQ+ +R K Q+ CL ++ ++ + +H E E E + AA+L+QS R + R++++ L+++++ VQ Q R + +R++ ER + VIQ+ + RF K L LR A IQ LWR R AR E +++ + K+ +A+++Q H RG + R R + ++Q L + C R R+SA II ++ R L + Q + + S IT+QS WR+ +ARR +R L + IQ + +M+ R FIR R+A ++Q ++RG+ R
Sbjct: 2136 LQCAWRRFRACKMLAHLRQEKLAKAELERKASAATTIQRTWRASMIRRREAKVKEMEKKRVIYEMQQKAATTVQRHVRGLQCRREFVRSKQ----AAVCVQSAWRRHQAKKSLEMLKKERVNKSAVVIQKFMR---GRLCRKGFLTSKQAAVTIQKQWRMKLAQKFLVCLRTQKKTMAATVIQKHVRGRLCRREIEGLRGSALILQKLWRAKKAREVVESLRAERQKEAAVLVQSVVRCASDRRKFLRLKRAAVCVQTQWRCVLAQREFMRLRLERQTHAAVVIQKNFHRFKAKKEL-----YALRC-AAVVIQKLWRARQARLELRKLRG----QQKDRAALILQKHARGFLCRKNLQRSQMAAQKIQGLWRVCLARRELLRLRDQRRKSATIII-----QKMFRGLQQRQAFAKIKGSVITLQSAWRVVRARRLFRKLRE--EKENKSALCIQSNWRMFQARHSFIRQRQAAVLMQCYWRGFLTR 2598 HSP 6 Score: 79.7221 bits (195), Expect = 3.395e-11 Identity = 125/484 (25.83%), Postives = 201/484 (41.53%), Query Frame = 0
Query: 337 WRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR--------ERQRII-QTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA---------LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRK-----SSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMR-----ESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIR----------------------------IRRAVTVIQKHYRGYQVRTAFKSDCKIKQTAL 764
W R Q AH +A R+Q WR ++A C + + +A+ AE + ++ AATTIQ WR + +RR E++R+I + + +AA +Q R Q R R QA V +Q +R+ + L+ ER+ +R + + S+ AA+ IQ WR ++ + LR ++ ++QK VRG + RR+ E R S ALI +Q LWR + AR ++A E + +A+L+QS R R KFLRL+R + +Q + +AQR + +R +A +IQ+ + R + + L L+ +A+ IQ LWR +AR R L + A +Q+ + ++ RK R + A +IQK +RG Q R AF KIK + +
Sbjct: 2116 WIRPLLAQRFAHQRAL-----AAVRLQCAWRRFRA----------CKMLAHLRQEKLAK----AELERKASAATTIQRTWRASMIRRREAKVKEMEKKRVIYEMQQKAATTVQRHVRGLQCRREFVRSKQAAVCVQSAWRRHQAKKSLEMLKKERVNKSAVVIQKFMRGRLCRKGFLTSKQ-AAVTIQKQWRMKLAQKFLVCLRTQKKTMAATVIQKHVRGRLCRREIEGLRGS-----------ALI------------------LQKLWRAKKAREVVESLRA----ERQKEAAVLVQSVVRCASDRRKFLRLKRAAVCVQTQWRCVLAQREFMRLRLERQTHAAVVIQKNFHRFKAKKELYALR------CAAVVIQKLWRARQARLELRKLR--GQQKDRAALILQKHARGFLCRKNLQRSQMAAQKIQGLWRVCLARRELLRLRDQRRKSATIIIQKMFRGLQQRQAF---AKIKGSVI 2535 HSP 7 Score: 76.6406 bits (187), Expect = 3.078e-10 Identity = 105/364 (28.85%), Postives = 167/364 (45.88%), Query Frame = 0
Query: 432 RNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQR-------------YIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEE-------------QSEMRLR---------HQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMR-----ESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHL-----THLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR 750
R EAA+ IQ R + +R A VR+Q +R+F R C + L+ LR E +A E ++ AA IQ WR R+R Y +K++ VQ+ VRG RR++ RS+ + +Q AWRR K LE Q MR R Q A IQ WRM++A++ ++ + K +A +IQ H RG + R + LR + + LQ L +A A+ + S+R E+A ++Q ++R ++ +K+ + ++A+ +Q+ WR A+R + L TH A IQ++ + +K+ +R A VIQK +R Q R
Sbjct: 2106 RIEAAVKIQQWIRPLLAQRFAHQRALAAVRLQCAWRRF--RAC--KMLAH---LRQEKLAKAELERKASAATTIQRTWRASMIRRREAKVKEMEKKRVIYEMQQKAATTVQRHVRGLQCRREFVRSKQAAVCVQSAWRRHQAKKSLEMLKKERVNKSAVVIQKFMRGRLCRKGFLTSKQAAVTIQKQWRMKLAQKFLVCLRT----QKKTMAATVIQKHVRGRLCRREIEGLRGSALILQKLWRAKKAREVVESLRAERQKEAAVLVQ------SVVRCASDRRKFLRLKRAAVCVQTQWRCVLAQREFMRLRLERQTH-------AAVVIQKNFHRFKAKKELYALRCAAVVIQKLWRARQAR 2445
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|919020531|ref|XP_013394208.1| (abnormal spindle-like microcephaly-associated protein homolog [Lingula anatina]) HSP 1 Score: 257.684 bits (657), Expect = 1.039e-66 Identity = 312/1181 (26.42%), Postives = 525/1181 (44.45%), Query Frame = 0
Query: 2 YLTLQRSVHIIQ---RSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTK---------------------------ARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWR-MWMSRRSYLRFQTEAQEELE-----------------HCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKF-----------------VQSLAHHL----KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAER----KLESLA---------------ATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERI-ALRHEAQERAWTESRSL--------------------------------AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQ---RRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAI-----TIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----------------------VRKKFIRIRRAVTVIQKHYRGYQVRTAFKS--DCKIKQTALLPDFPINEEL-SKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLLASS-NRVKKILTLPLNAKKLLESHKHYHRLHNKQMERGRRRN------NYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
Y LQR+ ++Q R+WR QRL IL + T +Q+ W+ H R+ LR+ K A+ LIQS + H+ ++F L+ A+V++Q FR+ ARRR+L M++A I ++ +G +KH E ++ +Q Y + W ++ +L+ +Y+ +Q R RK +L + + + IQ R W A+K++ KWA +Q+ R Y +H E + +A +Q+Y R M +R+ +R+ + Q + C + QA R I Y ++R + + LQA V+G + +++ +++ +QR +R K +Q+ L + R Q+A +Q+ +M Q R+ ++ +NA L IQ +R+H R AF R KL+S TIQSA R+ RR Q T+N ++IQSA R++ R V++Q R + R Q L R ++ ++ RA+ + R AAI IQ+ RG R Y +R+++I +Q VRG R Y R +VRV+Q+ R A+I+ +E+ E +R A IQ+ R M R + I+A A++IQ +RG QR ++ ++ I LQ+ + IAQ RR+V +A IQR +R +RL + L E ++ + S + T + R+ ++ R+YR + L A ++ I +Q W+ VR++ +R +A T IQ RG+Q R + D + A+ +++ KK+ +VR+++ A ATE+KKL NRT ALD L + + ++++L L LD TR S+ CC++++ N V ++ L+R CNRS+PHM+II +++ +NLAKY+ +R + + D V +TL+E++ IYRDK I+ K L+ +L R ++IL LP + +L H R H+ R +++ +Y +++ P +P + + P W +R D + DP A V+ L L
Sbjct: 2102 YKELQRAALVLQTRLRAWR-LGQEQRLRYNIL---LGATIT-LQAAWRGHVIREAYLRQRKAAI---------LIQSAVRRHMALQRFKELRRAAVIIQRRFREKMLCRSWFMYFHIHRGAAIVIAAAVRGWIARRRYLAMQQACLTIQRYARGWAARKHFLE------TKKACVTLQKYTRGWVAKKQYLKT---------KYACVTLQKYTRGWVARKHYLETKETCVTIQKYIRGWVARKQYLDTKWACVTMQKYARAYIARKHYIE------IRNAALVLQTYTRAMLQARKERVRYAQQRQAAIVIQAAYRARRARQFVHYLRCVINM-QALVRASIARNRYLRLRAACVTLQAWVRGCLVAKRYHDVRQATVSMQRVYRSNKLTRERMTEYQKLRQACIVLQAATRGLMVRKEMARKRQAAILVQSWVKMKQTREKFVTLRNAALVIQDRFRAHAKQCEEREAFLDTRSKIVKLQSAVRCFQARKAYLDTRTKVVTIQSAIRQYLARRRYQ---NTKN-CVVIIQSAIRRHLARRAYLNTKAKAVKMQAAVRGHLAR---QAYLGTRAKVVKLQSHVRAYQQRRQFLTVKEAVMTIQRVWRAVLLTREVRREYQIAVGAAITIQAAVRGHQTRCCYTRMRQAAIKIQSFVRGATARDRYHRQLRAVRVLQQHTR--AVIQGRKERREFLIRVGAAITIQAWVRGHMVRNKVKAIRA----------AVVIQKVYRGYRQRKQYQAMKEAAIVLQSYVRRLIAQKTYRRMVCEHRAAVCIQRVYRGYRLHKVLEEQRQKRAAVLSKVVHVAKTHLAAIRLQRSYRNYRAM--LVARQKITSVLI---LQRWIRAKLQRVNYLKLRAGITRLQSLVRQRLVRRHQAATSIQALVRGWQGRRQAQKWQDAIVTIQAIWRGRKTRQQMKDKKVIQVRRRLKEATMAATEEKKLCNRTTSALDFLLQYKQLSYILEALVHLDAATRLSSRCCERMVEGN--AVGVIYTLIRSCNRSLPHMEIIKYSVNILLNLAKYDKTRQAVYQVEDSV-DTLVELMQIYRDKGSSIFCKVCTLMGILCQDRARREEILKLPKMSDRLRSIHTLTLRKHSLNENRLIKKSKMAATKSYPGSTYVPFTPSKRP----MKIRPDWILRRDKMNDVSDPLHAVTFVMESLQL 3215 HSP 2 Score: 144.821 bits (364), Expect = 4.018e-31 Identity = 204/831 (24.55%), Postives = 370/831 (44.52%), Query Frame = 0
Query: 65 KRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKG--CLFQKHLNERIHLSLMNRSATKIQGYWK----MWRGRQAFLRIMADA----------------------------------------QEELRQYSA-----TLIQSQWRSHS----ERKAFLHLRHSTLRIQSEFRKWSAQKR----FASMKWAATIIQRSWRHYRFVQ----HLHE---------------------RIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHC--SATLIQAQWRVWIQLKAYKQ----MRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQS----YLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRG--------FRKFIQR----CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWA-TKIQSLWRMRMARREFAQIQASALEELKNYS-------------------AILIQS-----------HWRGCV-----------QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
K+ ++A +IQS ++AH ++ F A K A++VLQ+H R+ + R FL +K+ A +I +W++ C+ Q+ E HL ++ + +Q ++ M RG++ F ++ A Q + ++Y A + IQ ++R+ R+ F LR + L IQ ++R +R F +++ AA I+Q +R + +Q H+ + +F+LL Q+ +Q +R + R +Q+E H +A +Q +WR ++ +Q M+ +A+ +Q+ + ++RR++E +R+ Q WR Q +A ++K + ++A +QT+ R W+ Q Y A + +Q +R HV R A+ +RK AA IQSA RR+ QR + R AA++IQ +R + LC R I RG R +I R Q CL+ + R A + + E++ A + +Q + RGW +++Y+ + + + +QK RGW+ R+ Y ++ + IQ+ R + K+ L +WA +Q R +AR+ + +I+ +AL L+ Y+ AI+IQ+ H+ CV R ++LRLR C+ LQA + C+ +R +R++ +QR +R ++L R + +Y+ + Q+ I +Q+ R R+ A A +Q ++M R+KF+ +R A VIQ +R +
Sbjct: 1742 KQTKAAVVIQSAFRAHREKTAFIATKRAAIVLQTHVRRCQTRAVFLKLKQGALLIQQWYRAQKCV-QRDRREYQHL---KQAVSTLQQRYRAQKDMQRGKEGFQKLRRAAITLQQRYRAKKCMERSMQEFQRLKYATLKLQQRYRAQRCMQRDKQEYQAVKQAVSTIQQRYRAQKCMQRHRQEFQQLRRAVLAIQQKYRAQKQMQREFEEFQNLRQAALIVQHRYRAQKLMQRNRKEFHQLKRAVVTLQRRYRAQKQMQVNKEEFQLLRQAVLLVQRRYRACLCMR-------RSQQEFSHLKQAALTLQQRWRAQKSMQKSRQEYACMKSAAVTVQSVFRMCLERRRYEQLRRATVKAQALWR-----QRMARR-RYKELQRAALVLQTRLRAWRLGQEQRLRYNILLGATITLQAAWRGHVIREAYLRQRK----AAILIQSAVRRHMA---LQRFKELR-RAAVIIQRRFR--EKMLC--RSWFMYFHIHRGAAIVIAAAVRGWIARRRYLAMQQACLTIQRYARGWAARKHFLETKK-ACVTLQKYTRGWVAKKQYLKTKYACVTLQKYTRGWVARKHYLETKETCVTIQKYIRGWVARKQY-------LDTKWACVTMQKYARAYIARKHYIEIRNAAL-VLQTYTRAMLQARKERVRYAQQRQAAIVIQAAYRARRARQFVHYLRCVINMQALVRASIARNRYLRLRAACVTLQAWVRGCLVAKRYHDVRQATVSMQRVYRSNKLTRE--RMTEYQKLRQACIVLQAATRGLMVRKEM-------ARKRQAAILVQSWVKMKQTREKFVTLRNAALVIQDRFRAH 2525 HSP 3 Score: 109.383 bits (272), Expect = 3.182e-20 Identity = 179/757 (23.65%), Postives = 333/757 (43.99%), Query Frame = 0
Query: 57 RLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQK---HLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQA--QVKGWIQR--RQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWR----MWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWR---QYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRG----WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASAL-------------EELKNYSAIL-----IQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIR--------HLAEL-------------QKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR 750
RL L+L + ++ +I+ IQR C LK S+V +QT A R I WW+G + ++ + ++ L+ +R+ +Q + + R+ R A + +A +IQS +R+H E+ AF+ + + + +Q+ R+ + F +K A +IQ+ +R + VQ +R +++ L Q+ + +Q +R AQ++++ + ++++R +AI LQ + K ++R ++F+ K + LQ+ +R + +Q +++ + Q+ + IQ ++R M + RQ + + + A LAIQ+ YR+ Q +R+ E AA +Q +R ++ + ++ A + +Q +R Q Q N+ + QA + +QR +R + C++R E L+ AA+ +Q WR RQ Y ++ +++ VQ R + RR YE+ R + K Q+LWR RMARR + ++Q +AL E+ Y+ +L +Q+ WRG V R +LR R+ I +Q+ + +A +R +R +A IIQR +R L R H ++Y M Q+ +TIQ R AR+H+ + A T+Q+ + WV +K++++ + A +QK+ RG+ R
Sbjct: 1645 RLTKVLQLNQVKAVAIIK------IQRAFRCFLKKRSLV-----KQTSAVIR----------IQSWWRGVVARQRVIQMRHQVELARKSRAVVVVQTAVRKFLLRRHLARSHAARILSKQTKAAVVIQSAFRAHREKTAFIATKRAAIVLQTHVRRCQTRAVFLKLKQGALLIQQWYRAQKCVQ--RDRREYQHLKQAVSTLQQRYR--------------AQKDMQRGK--------------EGFQKLRRAAITLQQRYRAKKCMERSMQEFQRLKYATLKLQQRYRAQRCMQR--DKQEYQAVKQAVSTIQQRYRAQKCMQRHRQEFQQLRRAVLAIQQKYRAQK-----QMQREFEEFQNLRQAALIVQHRYRAQKLMQRNRKEFHQLKRAVVTLQRRYRAQKQMQVNKEEFQLLRQAVLLVQRRYRACL---CMRRSQQEFSHLKQ-------------AALTLQQRWRAQKSMQKSRQEYACMKSAAVTVQSVFRMCLERRRYEQLRRAT-----------------------------VKAQALWRQRMARRRYKELQRAALVLQTRLRAWRLGQEQRLRYNILLGATITLQAAWRGHVIREAYLRQRKAAILIQSAVRRHMALQRFKELRRAAVIIQRRFREKMLCRSWFMYFHIHRGAAIVIAAAVRGWIARRRYLAMQQACLTIQRYARGWAARKHF-------LETKKACVTLQKYTRGWVAKKQYLKTKYACVTLQKYTRGWVAR 2291
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1246178212|ref|XP_022434898.1| (abnormal spindle-like microcephaly-associated protein isoform X2 [Delphinapterus leucas]) HSP 1 Score: 257.299 bits (656), Expect = 1.123e-66 Identity = 284/1082 (26.25%), Postives = 519/1082 (47.97%), Query Frame = 0
Query: 33 KINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLI--QSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ-------AFLRIMADAQEELRQYS----------ATL-IQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWS-----------------------AQKRFASMKWAATIIQRSWRHYRFVQHLHER-------IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRM----------HKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALLW-LLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
++ A ++QS KM ++R++ L AL+ + + + I Q+ + ++ R+Q + A+V LQSHFR K R +L + +AA VI +++ ++ +N+R + + R+ +Q ++ ++ RQ A L+I Q R YS +TL IQ +R+H R FL R + + +QS +R W AQK F +K AA++IQ QHL R +++ L +A +QS WR +RR Q + +H A LIQ+ +R+++Q K +K M+ +A ++Q + + R+ + K + +LQ ++R + + + H H++A IQ+ +R++Q ++ Y + + + IQ++YR V ++A + ++ +L AA IQ+ +R VRR+ Q + + AA +I++ ++ Q+R + A + IQ +R RH+A+ + E + AA IQ+ +R W R+ Y+ + ++ +Q + RR + R+S +IQR WR + EQ M R+Q A IQ+ +R R+ F Q +++AL ++ Y I++ G +R K++ L+++ + LQAL + + ++R++ R R+ IQRA+R HR +++ + Q SAI IQ +R H+ + + A + IQ++++ +++RKK ++ VT IQ +RGY R K+DC KI+ +RQ++ N E+ KL +RTALAL L + ++ +L LK L+V T S+ CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +Y+ DKS I+TKT LL LL +NR + + ++ +K H H+++ +++ R++ + + SF P + +L P W +R D + +P A +MV++ L +
Sbjct: 1561 RLKNAAVKLQSIVKMKQTRKQYLHLRAAALKREEHMRVSCIKLQAFVRGYLVRKQVRLQRKAAVSLQSHFRMRKMRLYYLKIYKAAVVIQSYYRA--YKAQVNQRKNFLQVKRAVICLQATYRGYKVRQLIKQQSTAALKI----QTAFRGYSKRMKYQSVLQSTLKIQRWYRTHKTASDIRTHFLKTRAAVISLQSAYRGWKVRKQIRREHQAAVKIQSAFRMAKAQKEFGLLKTAASVIQ---------QHLRARAAGRRERLEYTALRLAAVMLQSTWRGRAARR---------QVQKQHKCAVLIQSCYRMYVQRKKWKIMKKAACLIQIYYRAYNTGRKQHHLYLKTKAAVVILQSAYRGMRVRKKIKEH------HKAAAAIQSSYRVYQTKKKYATYRASAVIIQRWYR--VTKIADRQRKEYLTLKKAAVKIQAVYRGVTVRRQTQHL----HAAATLIKAVFKMQQSRRRYHQMRTAAIIIQTAWR------------------RHKAR-KYLREVK--AACKIQAWYRCWKARKEYLAVLRAVRTIQGCFCTKLQRRRFLNVRASTIIIQRKWRAVLSGRTAHEQFLMTKRYQAACLIQANFRGYKGRQVFLQQKSAAL-TIQRY----IRARKTGKCERIKYVELKKSTVVLQALVRGWLVRKRILEQRAKIRLLHFTAAAFYHLSALRIQRAYRLHRALKNADDKQ-----VNSAIRIQRWFRARLQHKRFLQKHRFMKIQNEAQERTSQQNRAASVIQKAVRRFLLRKKQEKLDNRVTKIQALWRGYSWRK--KNDC------------------TKIKAIRQRLQCVNREIREENKLYHRTALALHYLLTYKYLSAILEALKHLEVVTGLSSLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIGYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYQEKPGDKVADKSRSIFTKTCCLLAVLLKRTNRASDVRSRSKVVDRIYSLYKLTAHKHKVNTERILCKRKKKSSMSISFIPETPVRTRMVSRLK--PDWVLRRDNLEEIMNPLKAIQMVMDTLGI 2550 HSP 2 Score: 159.458 bits (402), Expect = 1.293e-35 Identity = 214/841 (25.45%), Postives = 387/841 (46.02%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMA--DAQEELR----------QYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHER-------IQFRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWR----RFKFVQSLAHHL-------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNA-----------CLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRG----KFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L+ +I IN A IQ +W+ ++++LL K LE +N+SA++IQ +W+ + R+QF LK S++LQS R A + AA I + W+ CL +K +R ++ S IQ ++ WR R+ L+ A Q R + +A +IQS +R E + ++H+R + IQ+ FR + AQK + K + +Q+ ++ Y +L +R FR + +A QSYWRM R +L + + +QA R QL+ YK+M+ +A+V+Q + +I ++ ++ + + VLQ ++R R KF+ L + K+ R+ +A ++Q+ +M Q R+ YL + A C+ +Q + R ++ R + +RK AA ++QS +R ++R +I + AA+VIQS +R Y+ ++ + ++++R CLQ A + R + +S AA+ IQ+ +RG+++R +Y + +S++ +Q+ R +R + ++R++V +Q A+R + + K ++R HQ A KIQS +RM A++EF ++ +A +IQ H R ++ LR + LQ+ + A+R++ + A +IQ +R + + +K+K+M ++A IQ +R + R HL +A + + R M+ VRKK +A IQ YR YQ + + +
Sbjct: 1152 RAARLIQTTWRKYKLKKDLKRHQKRDKAARIIQSAVINFLTKRRFKKEVNAALVIQKYWRRLLAKRKLLMLKKEKLEKVQNKSASVIQRYWRRYSTRKQFLKLKYYSIILQSRIRMIIAVASYKRYLWAAVTIQRHWRACLRRKQDQQR--YEMLRSSTLIIQSAFRRWRQRKMQLQTEAAITLQRAFRERCVRKQVKEEKAAMVIQSWYRMQRELRKYIHIRSCVVIIQTRFRCFQAQKLYKRKKESILSLQKYYKAYLKGKVERTSYLQKRAAAIRLQAAFRGMKARNLRKQITAACVFQSYWRMRQDRLRFLNLKK---------NIIRLQAHIRKHQQLQKYKKMKKAALVIQIHFRAYISAKKVLASYQKTRSAVIVLQSAFRGVQARKKFIHILTSVIRIQSYYRAYVSRKKFLRLKNAAVKLQSIVKMKQTRKQYLHLRAAALKREEHMRVSCIKLQAFVRGYLVRKQVRLQRK----AAVSLQSHFRMRKMRLYYLKIYK----AAVVIQSYYRAYKAQVNQRKNF---LQVKRAV------ICLQ-------ATYRGYKVRQLIKQQSTAALKIQTAFRGYSKRMKYQSVLQSTLKIQRWYRTHKTASDIRTHFLKTRAAVISLQSAYRGWKVRK------QIRREHQAAVKIQSAFRMAKAQKEFGLLKT---------AASVIQQHLRARAAGRRERLEYTALRLAAVMLQSTWRGRAARRQVQKQHKCAVLIQSCYRMY------VQRKKWKIMKKAACLIQIYYRAYNTGRKQHHLYLKTKAAVVILQSAYRGMR---VRKKIKEHHKAAAAIQSSYRVYQTKKKYAT 1933 HSP 3 Score: 103.605 bits (257), Expect = 1.735e-18 Identity = 148/600 (24.67%), Postives = 275/600 (45.83%), Query Frame = 0
Query: 32 RKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQRE----QFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWR-GRQA---FLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQA------------------QVKGW---------------------------IQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAER--KLESLAATTIQSAWRRNQVRRERQRIIQTRNE--------------AALVIQSAWRQYQN-RLCLERRIQACVRIQRGFRKFIQRCCLQRCLSER--IALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFA 559
R+ +Q A +IQS ++M ++++E LK A A++IQ H +A ++ AL+ A+V+LQS +R ARR+ + A +I ++ + +R +M ++A IQ Y++ + GR+ +L+ A + ++QS +R RK + IQS +R + +K++A+ + +A IIQR +R + +R ++ L ++A KIQ+ +R RR Q + H +ATLI+A +++ + Y QMR +AI++Q +++ W +QRR+F + + S ++QR WR ++ + +Q+A IQ +R ++ RQ +L+ ++A L IQ+Y R AR + ER +E +T + A R + R+RI++ R + +AL IQ A+R ++ + ++++ + +RIQR FR +Q +R L + + +++EAQER ++R+ + I QK VR +++R+ E+ + V IQ WR ++
Sbjct: 1763 RREHQAAVKIQSAFRMAKAQKEF-GLLKTA--------ASVIQQHLRARAAGRRERLEYTALRLAAVMLQSTWRGRAARRQVQKQHKCAVLIQSCYRMYV------QRKKWKIMKKAACLIQIYYRAYNTGRKQHHLYLKTKA---------AVVILQSAYRGMRVRKKIKEHHKAAAAIQSSYRVYQTKKKYATYRASAVIIQRWYRVTKIADR--QRKEYLTLKKAAVKIQAVYRGVTVRR---------QTQHLHAAATLIKAVFKMQQSRRRYHQMRTAAIIIQTAWRRHKARKYLREVKAACKIQAWYRCWKARKEYLAVLRAVRTIQGCFCTKLQRRRFLNVRASTIIIQRKWRAVLSGRTAHEQFLMTKRYQAACLIQANFRGYKGRQVFLQQKSAALTIQRYIR---ARKTGKCERIKYVELKKSTVVLQALVRGWL--VRKRILEQRAKIRLLHFTAAAFYHLSALRIQRAYRLHRALKNADDKQVNSAIRIQRWFRARLQH---KRFLQKHRFMKIQNEAQERTSQQNRAASVI-------------------------QKAVRRFLLRKKQEKLDNRVTKIQALWRGYS 2294 HSP 4 Score: 94.3597 bits (233), Expect = 1.022e-15 Identity = 118/465 (25.38%), Postives = 222/465 (47.74%), Query Frame = 0
Query: 326 QKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYR-----SHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQR------IIQTRNEAALVIQSAWRQYQNRLCLERRIQACVR-----------------IQRGFRKFIQR---------CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
+ R+AR++Q +WR++K + L H ++ ++A IQ+ + ++ + + NA L IQKY+R + L + K+++ +A+ IQ WRR R++ + I+Q+R + + S R + ++R +AC+R IQ FR++ QR LQR ER + +E+ AA++IQS +R + ++YI +R +++Q + R + ++ Y+R + S+ +Q+ ++ + L ++E S ++ R A ++Q+ +R AR QI A A + QS+WR R +FL L++ IRLQA + ++ M+++A +IQ +R + I L Y+ + I +QS +R +AR+ + H+ + IQ + +V RKKF+R++ A +Q + Q R +
Sbjct: 1150 ETRAARLIQTTWRKYKLKKDLKRH---QKRDKAARIIQSAVINFLTKRRFKKEVNAALVIQKYWRRLLAKRKLLMLKKEKLEKVQNKSASVIQRYWRRYSTRKQFLKLKYYSIILQSRIRMIIAVASYKRYLWAAVTIQRHWRACLRRKQDQQRYEMLRSSTLIIQSAFRRWRQRKMQLQTEAAITLQRAFRERCVRKQVKEEK--------AAMVIQSWYRMQRELRKYIHIRSCVVIIQTRFRCFQAQKLYKRKKESILSLQKYYKAY-LKGKVERTSYLQKRAA-AIRLQAAFRGMKARNLRKQITA----------ACVFQSYWRMRQDRLRFLNLKKNIIRLQAHIRKHQQLQKYKKMKKAALVIQIHFRAY--ISAKKVLASYQKTRSAVIVLQSAFRGVQARKKFIHIL-------TSVIRIQSYYRAYVSRKKFLRLKNAAVKLQSIVKMKQTRKQY 1582
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1334647637|ref|XP_023586136.1| (abnormal spindle-like microcephaly-associated protein [Trichechus manatus latirostris]) HSP 1 Score: 256.914 bits (655), Expect = 1.960e-66 Identity = 317/1198 (26.46%), Postives = 550/1198 (45.91%), Query Frame = 0
Query: 3 LTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAH----IQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHS----ERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATK-IQSYWRMWMSRRSYLR--------------FQT---EAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLES-LAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWR------QYQNRLCLERRIQ---------------------ACVRIQRGFRKFI-QRCCLQRCLSERI-ALRHEA--------QERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMV--------QKQ---------------------------VRGWI----VRRDY------------------ERSR-----SSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY-----------RHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLW-LLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMER---GRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
L Q++V IQ S+RR + ++++E+ + A IQ+ ++MHR+R LKR ++TL Q ++A+ +QRE + K+++VV+Q+ FR K RR M AA I ++ + +K M R+A IQ ++M R F + ++++ LIQ +R++ +R+ ++ +HS + IQ+ ++ A++ AA +IQ +++ YR + +++IQ+ ATK IQ +R +++ L+ FQ Q + EH +AT+IQ ++ + + Y Q+R + +Q + + I + ++ Q S+R FK + +RMH +AT+IQ +RM +AR Y + A + IQ YYRS+V R+ + R L + +A TIQ+A+R +VR ++ + + AA+VIQSA+R QYQ RIQ A V IQ+ FRK + +R Q+C + RI + H A Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++ QKQ ++ W R++Y ER+R +S +IQR WR + + E+S M RHQ A IQ+ +R R+ F + +++AL +N I++ +R K+ L+++ + LQA+ + + ++R++ + R+ IQRA++RH I++ K S I IQ +R R+ + R + A IQ++++ +++RKK + +T IQ +RGY R K+DCK KI+ VR + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + + V +N+AKYE + + + ++ ++TL+E+L +YR+K+ D I+TKT LL LL +++R + + P ++ +K R H ER +++N+ + F P + + L P W +R D + +P A +MV++ L L
Sbjct: 2315 LRFQKAVIKIQSSYRRLMVKKKMQEM------RRAAVLIQAAFRMHRARVRYQ-------ALKR--ASTLTQLRYRANRVGKLQREHYLKQKSSAVVIQAAFRGMKTRRHLKAMHLAAITIQSAYRRLMAKKK---------MQRAAVLIQATFRMHRTYVRF---------QTCKHASVLIQQHYRAYRAAKLQRENYIKQQHSAVVIQAAYKGMKARQLLRKKHRAAIVIQSTYKMYR-QYYFYQKIQW------ATKVIQEKYRANKTKQKALQHSALKKATACIQEGFQDMNIGKQIQKEHQAATVIQKHFKAFKVRRHYLQLRAAVFFVQRRYRALIA---MQMHTQAVICPQSSYRGFKVQNDI------QRMHLAATQIQALYRMHRARAVYQAKKTAIIVIQNYYRSYV-RVKMERNRFLAAQKSAPTIQAAFRGMKVR-QKLKNESEKEMAAIVIQSAFRCYRAKTQYQAVGSAAVRIQTWYKASLLVHSQRAEYASQRKAAVTIQKAFRKVVARRLETQKCAALRIQSFLHVAVHRRRFVQQKRAVVTLQQYFRTWQTRKQFLLCRKAAVVLQNHYRAFLCAKYQRQAYLQIRSSVIIIQARMKGFIQKQKFQKIKDSTIKIQAVWRKYKAMKAACKIQAWYRCCRARKEYLAVLKAVKIIQGCFYTKLERTRFLNMRASTIIIQRRWRAVLSGRIVRERSLMIKRHQAACLIQANFRGYKGRQVFLRQKSAALIIQRN-----IRARKSAKCERIKYAELKKSTVVLQAMIRGWLVRKRILEHKAKIRLLHFTAAAYYHLSALRIQRAYKRHLAIKNA------KKQISSVICIQRWFRARLQRKRFIQKYESIIKIQREVQERQDQQNKAALVIQKAVRRFLLRKKQEKFNSGITKIQALWRGYSWRK--KNDCK------------------KIKAVRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAITKIFV-LIRSCNRSVPCMEVIRSAVQVLLNVAKYEKTTSAVYD-VENCIDTLLELLQMYREKAGDRVADKGGSIFTKTCCLLAVLLKTTSRASDVRSRPKVVDRIYSLYKLTARKHKMNTERILYKQKKNSSISIPFIPETPVRTSIVSR--LMPDWVLRRDSLEEITNPLKAIQMVMDTLGL 3425 HSP 2 Score: 170.629 bits (431), Expect = 3.864e-39 Identity = 216/845 (25.56%), Postives = 391/845 (46.27%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMA-----------DAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHER---IQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHC--------------SATLIQAQWRVWIQ----LKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQ----RCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCK 758
R+ +IQ +WRRY L + L +L L+++I A IQ +W+ ++++LL + LE +N+SA +IQ +W+ + R++F LK S++LQS R A + A VI + W+ +K +R ++ S+ IQ ++ W+ R+ L+I A ++ ++ SA +IQS +R H E + + H+R + IQ FR + AQK + K + IQ+ ++ Y Q+L +R IQ FR + ++A QSYWRM + +L+ + + H +A +IQA +R +I L +Y++ R + IVLQA +G R++F S +Q +R + H K+ + + ++Q+ +M QAR+ YLR + A L IQ++YRS ++A + + + + I+ A+ R + R++ R+ + +AA+ +QS +R + R + +A V IQ + + F+Q CLQ A + R + +S+AA+ IQ+ +RG+ +R +Y + +S++ +Q+ R + D + ++R++V +Q +R + + K ++R H A KIQS +RM AR++F ++ + L +IQ H R G QR +++ LRR + LQA KA +R+ + A IQ +R + + +K++ + ++A+ IQ+ +R + + RHL +++ + AV ++Q YRG +VR K K
Sbjct: 1274 RAARLIQTTWRRYKLKTDLKRYQERDKAARIIQSAVINFLTKLRLKKEII-AALVIQKYWRRFLAQRKLLMLKREKLEKTQNKSAAIIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVVIQRHWRAYFRRKQDQQR--YKMLKSSSLVIQSRFRRWKRRKMQLQIKAVIILQRAFRRWQVRKRAKEKSAIVIQSWYRMHKELRKYTHIRSCVVIIQRRFRCFQAQKSYKRKKESVLTIQKYYKAYVKGKIERTQYLQKRAAAIQLQAAFRRMKARNLHRQIRAACVFQSYWRMRQEKLQFLKLKKIVIKLQAHVRKHQQLQKYKKVKKAALIIQAHFRAYISARKVLASYQKTRSAVIVLQAAYRGMQARKKFIHILTSVIKIQSYYRAY------ISHRKFMSLKNATVKLQSIVKMKQARKQYLRLREAALCIQRWYRSK--KMAARKREEYIRVQKSCIKLQAFVRGYLVRKQMRL---QRKAAISLQSYFRMRKMRQYYLKIYKATVVIQNYYHANKAQVNQRKNFLQIKRAATCLQ-------AAYRGYKVRQLIKQQSIAALKIQTAFRGYNKRVKYQSVLQSTLKIQRWYRAYKSVYDTRTLFLKTRAAVIFLQSVYRGWKVRK------QIRREHNAAMKIQSAFRMSKARKQFRSLRRATL---------VIQQHLRARTEGKKQRTEYIELRRVVLVLQATWKARKLRRQFQRQHKCAVAIQSYYRMY------VQQKKWRGLKKAALLIQTYYRAYSIGQKQRHL--------------------------YLKTKAAVVILQSAYRGLRVRKKVKESNK 2050 HSP 3 Score: 136.346 bits (342), Expect = 1.468e-28 Identity = 190/752 (25.27%), Postives = 360/752 (47.87%), Query Frame = 0
Query: 69 SATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWW-----------------KGCL----FQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATL-IQSQWRSH----SERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMS------------------RRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKL---ESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR--KFIQRCCLQRCLSERIALRHEAQERAWTESRS-----LAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHW---RGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
S IQS+++A+I +F +LK A+V LQS + +AR+++L ++ AA I +W+ K C+ F + R + L ++A +Q Y++M + RQ +L+I Y AT+ IQ+ + ++ ++RK FL ++ + +Q+ +R + ++ AA IQ ++R Y ++R++++ + QS KIQ ++R + S + Y ++ Q EH +A IQ+ +R+ K ++ +R + +V+Q A+ +G QR ++ +R VLQ +W+ K + +++R H+ A IQ+ +RM+ ++ + + A L IQ YYR++ Q +R L A +QSA+R +VR++ ++ N+AA+ IQS ++ Y+ + + + + IQR +R K ++ + + A++ +A R R LAA I++ ++ + RY +R ++I++Q + R + I R Y +V +IQ +R L + +R AT IQS +R ++ F++ LK + + Q +W +Q ++ +LR + I +QA+ + A+R L M +A +IQR +R + R L+K +AI +Q R ++A RH + + A IQ S + +V+KK +RRA +IQ +R ++ R +++
Sbjct: 1663 SVIKIQSYYRAYISHRKFMSLKNATVKLQSIVKMKQARKQYLRLREAALCIQRWYRSKKMAARKREEYIRVQKSCIKLQAFVRGYLVRKQMRLQRKAAISLQSYFRMRKMRQYYLKI----------YKATVVIQNYYHANKAQVNQRKNFLQIKRAATCLQAAYRGYKVRQLIKQQSIAALKIQTAFRGY------NKRVKYQSVLQSTLKIQRWYRAYKSVYDTRTLFLKTRAAVIFLQSVYRGWKVRKQIRREHNAAMKIQSAFRMSKARKQFRSLRRATLVIQQHLRARTEGKKQRTEYIELRRVVLVLQATWKARKLRR------QFQRQHKCAVAIQSYYRMYVQQKKWRGLKKAALLIQTYYRAYSIG---QKQRHLYLKTKAAVVILQSAYRGLRVRKK----VKESNKAAVTIQSNYKAYKTKKKYATQRASAIMIQRWYRDTKIAKQQRREYLNLKNAAIKIQAVYRGIRVRRQIQRMHLAATFIKAMFKMHQSKARYHTMRTAAIVIQVRYRAYCQCKIQRAKYLTILKAVNIIQARFRG------LRVRQTLRKMQIAATLIQSYYRRYRQQKYFSK--------LKKVTKTVQQRYWAVKERNIQFQRYNKLRYSVICIQAVFRGMRARRHLKIMHLAATLIQRRFRTLMMRRRFLSLKK------TAIWVQ---RKYRANVCARHRLQQSLRFQKAVIKIQSSYRRLMVKKKMQEMRRAAVLIQAAFRMHRARVRYQA 2362 HSP 4 Score: 130.183 bits (326), Expect = 1.377e-26 Identity = 177/678 (26.11%), Postives = 305/678 (44.99%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQ----TKARRRFLTMKRAAGVIHKWWKGC-LFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWI----QLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWR---RNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRV---------------IQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASAL---------EELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL 638
YL L+ +V +QR +R LI + Q QS ++ + + ++ +R+ LA AT IQ+ ++ H R + A KTA +V+Q+++R R RFL +++A I ++G + QK NE S +A IQ ++ +R + + + + A Y A+L+ HS+R + R + + IQ FRK A +R + K AA IQ S+ H RFVQ ++ +Q Y+R W +R+ +L L +A ++Q +R ++ Q +AY Q+R S I++QA++KG+IQ+++F+ K S +Q WR++K + ++A +IQ +R +AR+ YL A IQ + + + R F R + IQ WR ++ RER +I+ R++AA +IQ+ +R Y+ R R+ A + IQR R A++ A E R +Y L+KS++++Q +RGW+VR+ ++ +R+ IQRA++R IK ++Q IQ +R R+ R+ F Q S + ++ +N +A++IQ R + R K + ++QAL
Sbjct: 2598 YLQLRAAVFFVQRRYR---------ALIAMQMHTQAVICPQSSYRGFKVQNDI-QRMHLA--------ATQIQALYRMHRARAVYQAKKTAIIVIQNYYRSYVRVKMERNRFLAAQKSAPTIQAAFRGMKVRQKLKNE----SEKEMAAIVIQSAFRCYRAKTQYQAVGSAAVRIQTWYKASLL-----VHSQRAEYASQRKAAVTIQKAFRKVVA-RRLETQKCAALRIQ-SFLHVAVHRRRFVQQ----------KRAVVTLQQYFRTWQTRKQFL---------LCRKAAVVLQNHYRAFLCAKYQRQAYLQIRSSVIIIQARMKGFIQKQKFQKIKDSTIKIQAVWRKYKAM-------------KAACKIQAWYRCCRARKEYLAVLKAVKIIQGCFYTKLERTRFLNMRA----STIIIQRRWRAVLSGRIVRERSLMIK-RHQAACLIQANFRGYKGRQVFLRQKSAALIIQRNIR---------------------ARKSAKCE------------------RIKYAELKKSTVVLQAMIRGWLVRKRILEHKAKIRLLHFTAAAYYHLSALRIQRAYKRHLAIKNAKKQISS------VICIQRWFRARLQRKRFIQKYESIIKIQREVQERQDQQNKAALVIQKAVRRFLLRKKQEKFNSGITKIQAL 3164 HSP 5 Score: 92.0485 bits (227), Expect = 6.715e-15 Identity = 127/461 (27.55%), Postives = 208/461 (45.12%), Query Frame = 0
Query: 326 QKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQR----QRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQI--------------QASALEELKNYSAILIQSHW----RGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAW--RRHRL---------------IRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
+ R+AR++Q +WRR+K L +++ ++A IQ+ + + + A L IQKY+R F A+RKL L +R+++ +T+N++A +IQ WR+Y R + + +Q R I +R L W A ++IQ HWR + +R QRY L+ SS+++Q + R W RR + +V ++QRA+RR+ + KR +E+S A IQS +RM R++ I QA + K S + IQ ++ +G ++R ++L+ R I+LQA + A R L +A + Q W R+ +L +R +LQKYK + ++A+ IQ+ +R + + R SA + R MQ RKKFI I +V IQ +YR Y
Sbjct: 1272 ETRAARLIQTTWRRYKLKTDLK---RYQERDKAARIIQSAVINFLTKLRLKKEIIAALVIQKYWRR------FLAQRKLLML----------------KREKLEKTQNKSAAIIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYL--------------W------ATVVIQRHWRAYFRRKQDQQRYKMLKSSSLVIQSRFRRW-KRRKMQLQIKAVIILQRAFRRWQVRKRAKEKS--------AIVIQSWYRMHKELRKYTHIRSCVVIIQRRFRCFQAQKSYKRKKESVLTIQKYYKAYVKGKIERTQYLQKRAAAIQLQAAFRRMKA-RNLHRQIRAACVFQSYWRMRQEKLQFLKLKKIVIKLQAHVRKHQQLQKYKKVKKAALIIQAHFRAYISARKVLASYQKTRSAVIVLQAAYRGMQ---ARKKFIHILTSVIKIQSYYRAY 1674 HSP 6 Score: 70.8626 bits (172), Expect = 1.854e-8 Identity = 98/371 (26.42%), Postives = 178/371 (47.98%), Query Frame = 0
Query: 427 RIIQTRNE--AALVIQSAWRQYQNRLCLER---RIQACVRIQRGFRKFIQRCCLQ--------------RCLSER--IALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASAL-----------EELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
R++ R E AA +IQ+ WR+Y+ + L+R R +A IQ F+ + L+ R L++R + L+ E E+ +S A +IQ +WR ++ R+R++ L+ SI++Q ++R I Y+R + VIQR WR A +R ++Q ++ + IQS +R R+ QI+A + + K SAI+IQS +R + K+ +R + +Q + AQ+ +ES IQ+ ++ + ++ E +Y +AI +Q+ +R KAR +R + A Q +M + +F+++++ V +Q H R +Q +K K+K+ AL+
Sbjct: 1265 RLLDLRKETRAARLIQTTWRRYKLKTDLKRYQERDKAARIIQSAVINFLTKLRLKKEIIAALVIQKYWRRFLAQRKLLMLKREKLEKTQNKS----AAIIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVVIQRHWR--AYFRRKQDQQRYKMLKSSSLVIQSRFRRWKRRKMQLQIKAVIILQRAFRRWQVRKRAKEKSAIVIQSWYRMHKELRKYTHIRSCVVIIQRRFRCFQAQKSYKRKKESVLTIQKYYKAY--VKGKIERTQYLQKRAAAIQLQAAFRRMKARNLHRQIR--------AACVFQSYWRMRQEKLQFLKLKKIVIKLQAHVRKHQQLQKYK---KVKKAALI 1616
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1304961362|ref|XP_023103749.1| (abnormal spindle-like microcephaly-associated protein homolog isoform X3 [Felis catus]) HSP 1 Score: 256.529 bits (654), Expect = 2.183e-66 Identity = 290/1088 (26.65%), Postives = 513/1088 (47.15%), Query Frame = 0
Query: 33 KINQCATQIQSFWKMHRSRQELL-------------RRLKLALELKRNQ------SATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKW----SAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLK----AYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQA----RQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALV------IQSAWRQYQNRLCLERRIQACVRIQRGFRKF-----IQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDY------------------ERSR-----SSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRM-----------HKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMER---GRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
++ ++QS KM ++R++ L R +K+A LKR + S +Q+ + H+ R+Q + + A+V LQS+FR K R+ +L M +AA VI +++ ++ +++R + + R+ T +Q ++ ++ RQ Q+ + +A IQ+ +R +S+RK + ++ ST++IQ+ +R + + +F K A +Q ++R ++ R Q R Q+A +IQS +RM +++ + F+T +A +IQ R W K Y ++R +A++LQ+ KG I RRQ Q + A ++Q +R KW M ++A IQ +R ++ RQ YL+T+ A + IQ YRS R + K AA IQS +R + ++ R A L+ I+ A RQ + L L++ V+IQ FR IQ + + H+A+ R + + R+ AA+LIQ+ WR + R +Y+ K++ +Q R W R++Y ER+R +S +IQR WR + E M RHQ A IQ+ +R R+ F + +++AL ++ Y I++ G +R K++ L+++ + LQAL + + ++R+ R R+ IQRA++ H ++++ K S I +Q +R H + R L + A + IQ++++ +++RKK +I +T IQ +RGY R K+D KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + ++ ++TL+++L +YR+K D I+TKT LL LL ++NR + + ++ +K R H ER +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 1679 RLKHATVKLQSIVKMKQTRKQYLHLRAATLFIQQWYRSIKVA-ALKREEYVQMRESCIKLQAFVRGHLVRKQMRSQRKAAVSLQSYFRMRKMRQHYLEMYKAAVVIQNYYRA--YKAQVSQRKNFLQVKRAVTCVQAAYRGYKVRQLI------KQQSI---AALKIQTAFRGYSKRKKYQYVLQSTIKIQTWYRTYRTVRDVRMQFLKTKAAVISLQSAYRGWKV------RTQIRRELQAAVRIQSAFRMAQTQKQFRLFKT---------AALVIQQHLRAWSAGKKQRMEYTELRNAALMLQSTWKGKIVRRQIRKQHKCAVIIQSYYRMH------VQQKKWDIMKKAARLIQMYYRAYRIGRRQRQLYLKTKAAIVIIQSAYRSMRVRKKIKEYNK----AAVAIQSTYR---AYKAKKNYATYRASAVLIQRWYRNIKIANRQRKEYLNLKK---TAVKIQAVFRGIRVRRRIQHMHTAATFIKAMFKMHQAKVR-YHKMRT-AAVLIQAAWRSYKAR-KYLCKVKAACKIQAWYRSWKARKEYLAILKAVKVIQGCFYTKLERTRFLNMRASTIIIQRKWRAMLSGRIAHEHFLMIKRHQAACLIQANFRRYKGRQVFLRQKSAAL-TIQRY----IRARKAGKCERIKYVELKKSTVVLQALVRGWLVRKRISEQRTKIRLLHFTAAAYCHLSALRIQRAYKLHMVMKNA------KKQVNSVICVQRWFRTRLQQKRFAQKCHSVIKSQRELQEHMSQQNRAASVIQKAVRRFLLRKKKEKINNGITKIQALWRGYSWRK--KND------------------GTKIKAIRLSLQLVNREIREENKLYKRTALALHCLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAVSKIFV-LIRSCNRSVPCMEVIRYSVQVLLNVAKYEKTTAAVYH-VENCIDTLLDLLQMYREKPGDKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTARKHKMNTERILYTQKKNSSISIPFIPETPIRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 2684 HSP 2 Score: 161.77 bits (408), Expect = 2.517e-36 Identity = 220/860 (25.58%), Postives = 399/860 (46.40%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKR-----------------------NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWR--------HYRFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRR----QFESQKRSARVLQRSWR----RFKFVQSLAHHL-------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRS---------------------------HVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y ++ +L ++ ++ A IQS S+Q L + + AL +++ N+SA +IQ +W+ + R+QF LK SV+LQS R A + A I + W L +K +R ++ S IQ ++ W+ + L+I A Q R++ SA +IQS +R H E + ++HLR + IQ+ FR AQK + + A IQ+ +R H ++Q IQ FR + ++A QSYWRM RR RF + ++ +QAQ R+ QL+ YK+++ +A+++Q ++ + + ++ + + VLQ ++R R KF+ L + K+ R+ + ++Q+ +M Q R+ YL + A L IQ++YRS H+ R +++RK AA ++QS +R +R+ RQ ++ +AA+VIQ+ +R Y+ ++ QR + F+Q ++R ++ A + R + +S+AA+ IQ+ +RG+++R++Y + +S+I +Q R + RD + +++++V +Q A+R + + ++++R Q A +IQS +RM +++F + +AL +IQ H R G QR ++ LR + LQ+ K I +R++ + A IIQ +R H + +K+ +M ++A IQ +R ++ R R L +A + + RSM+ VRKK +A IQ YR Y+ + + +
Sbjct: 1270 RAARLIQTTWRKY---KQKTDLKRHQERDKAARIIQSAVISFLSKQRLKKEINAALAIQKHWRRLLAQRKLLMLKKEKLEKVQNKSALVIQRYWRRYSTRKQFLKLKYYSVILQSRIRMILAVTSYKRYLWATVTIQRHWLAYLRRKRDQQR--YEMLKSSCLIIQSVFRRWKQHKMRLQIKATIILQRAFREWHVRKRAKEEKSAVVIQSWYRMHKELRKYIHLRSCVVIIQTRFRCLQAQKSYKRRREAILTIQKFYRAHLKGKTEHANYLQKRAAAIQLQAAFRGMKARNLHRQIRAACVFQSYWRM---RRDRFRFLNLKKITIK------LQAQVRMHQQLQKYKKIKKAALIIQIHLRASVLAKRALASYQKTRSAVIVLQSAYRGMQARRKFIHILTSIIKIQSYYRAYISRKKFLRLKHATVKLQSIVKMKQTRKQYLHLRAATLFIQQWYRSIKVAALKREEYVQMRESCIKLQAFVRGHLVRKQMRSQRK----AAVSLQSYFR---MRKMRQHYLEMY-KAAVVIQNYYRAYKAQVS-----------QR--KNFLQ---VKRAVTCVQAAYRGYKVRQLIKQQSIAALKIQTAFRGYSKRKKYQYVLQSTIKIQTWYRTYRTVRDVRMQFLKTKAAVISLQSAYRGWKV------RTQIRRELQAAVRIQSAFRMAQTQKQFRLFKTAAL---------VIQQHLRAWSAGKKQRMEYTELRNAALMLQSTWKGKIVRRQIRKQHKCAVIIQSYYRMH------VQQKKWDIMKKAARLIQMYYRAYRIGRRQRQLYLKTKAAIVIIQSAYRSMR---VRKKIKEYNKAAVAIQSTYRAYKAKKNYAT 2067
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|871222755|ref|XP_012936151.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein homolog isoform X1 [Aplysia californica]) HSP 1 Score: 255.758 bits (652), Expect = 4.799e-66 Identity = 312/1193 (26.15%), Postives = 534/1193 (44.76%), Query Frame = 0
Query: 33 KINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF----------QKHLNE------RIHLSLMN-----RSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSH----SERKAF-----------------LHLRH-----STLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI-QACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSE---------------MRLRHQWA------TKIQSLWRMRMARREFAQIQASALE---ELKNY-------------------------------------SAILIQSHWRGCVQRGKFLRLRRTCIRLQAL----------------------------------AKACIAQR--------RLVSMRESARIIQRAWRRH----RLIRHLAE-----------LQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIR---RAVTVIQKHYRGYQVR-----TAFKSDCKIKQTALLPDFPINEE-----LSKKIE------------------EVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERGRRRNNYLP-----NSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLALKP 1019
KI +QS W++ R+R+ L R+L+ E K N+SA IQS+W+ R F + A+V++Q ++R RR+ + AA VI W++ C+ +KHL E R +L+ N ++A IQ +++ +R R FL + + ++ +IQ +R++ R+ + L LRH S ++IQ+ FR + ++ + + AA +IQ +R + +Q ER +F Q+A IQS +R + + Y T SA IQA R K + ++ +A++LQ A++ G + R F S + S ++QR +R K + L L +R +A +IQ+ +R W RQ YL + AC+ Q+ YR+ + + E K +A IQ WRR + + + +S +Q RL E+R+ Q +R + +QRC R + ++ L +++ +E R AA+++Q +R + R +Y R + +Q+ +RG+ VRRD+ER R +IQR WR L K ++ E +R R ++A TKIQ+ RM + + F ++ + + L++Y S + +QSHWR C QR +F R + L+AL ACI QR RL ++A IIQ+A+R+H R ++H + +Q+ + +SA+ IQS R + A R ++ + + T+Q S++ W+ R++ +R RA+ +Q RGY VR ++F S + A L I EE S KI+ + R+++ ++ ATE+K LG+R + ALD L R +D+A++L + L+V+TR S CC++++ + V L L CNRSIPHM+II +D +NLAKY+ + V++E ++ + T++E+++IYR+K I+ K LL +L R ++++ LN L+E + H L ++++ R SF + A P + + P W + +D + DP + V++ L + P
Sbjct: 2529 KIKGSVITLQSAWRVVRARR-LFRKLR---EEKENKSALCIQSNWRMFQARHSFIRQRQAAVLMQCYWRGFLTRRQLEKSQEAAMVIQCWYRACVAARHQRLEFIEKKHLAELVQKMWRGYLARRNYQRERQAAIVIQAHFRCFRRRLKFLAL---------RLASVIIQRGYRNYRLGKQTRQEYIAITQAACTLQRWYRKCLELRHAQQISSAIKIQAAFRAYKTRQMVTTKRNAALVIQMKFRAH--LQMREERRKFLEQKQAAVTIQSCFRGYREQVMYKNILT---------SAIRIQALERKRQDRKRFLALKQAAVILQRRYRAKMLGLVFREAFLSIRSSVIIIQRFYRAVKVGEQLKELLDTQRA--AAIKIQSTYRGWSLRQDYLMLRAACVCCQRRYRAVQLGRSVRQEMKHRCVATRVIQREWRR-YLCVREAKRELEERREEVRRESQRQQEAERLAEEQRLMQEKAEDERKVFE-MQRCQAARVIQKQFVL---YRQKLCSERREKAAVMVQKCFRAYLVRCKYQETRNKLLFLQRLIRGFAVRRDFERQRLVAVLIQRWWRATLLAKHCRQEFESSRDAAVRIQTMYRMIRQRREYALSLQRVTKIQACVRMHVEHKRFIHVKCATIAIQRSLRSYLAMRRDRQQFLAAKHSAIKIQCEIRKWLACRRHKQEASVVALQSHWRMCQQRKEFQDAREAAMTLRALWESSQDNKQQQEHAARSIQLLFRNYMNKKLCLEHTAACIIQRAFRTFHQGRLQVKADAASIIQKAFRKHLAHKRQVQHKSAEAIQLAFRQHLIQRQAIKNESAVVIQSQVRRYLACRRFQAILG-------SVVTLQASVRGWLARQRAEELRKEQRALVFLQAQVRGYLVRKKVLNSSFFSCVQPVLQARLD--AIQEERKQRKASTKIQALWRGYKVRRNSRSRRLIQARKRISELSQEATEEKTLGSRMSSALDYLLRDKDVAYILEAMMHLEVSTRLSPVCCERMIEVD--AVPALYRLAASCNRSIPHMEIIKHTVDTLLNLAKYDKTVAVVME-PEESISTIMELMLIYREKG-PIFYKCCMLLGILGLDPRRRQVI---LNQAHLIERLQSIHSLTLRKLKVSRTHKATQAKMAAMKSFNCTMPVATPTK-RRRIRPQWVLAKDTMHEFDDPLTSISFVMDVLHIGP 3673 HSP 2 Score: 169.859 bits (429), Expect = 6.761e-39 Identity = 204/774 (26.36%), Postives = 367/774 (47.42%), Query Frame = 0
Query: 12 IQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKT-----ASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLR-----HSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLL-----NQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQM-----RCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLE-SLAATTIQSAWRRNQV--RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWR----GWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCK 758
+Q +WRR+ + LE L ER +N+ A IQ F + R+ L Q+A IQ W+ + ++ L+T A+ V+Q H R RR ++ +A ++ K W+ + + E + +A +Q + R+ FLR+ + +A +Q+QWR ++ F+ LR H+ + IQ F ++ A+K +++ AA +IQ+ WR R++ R L +++A +Q + R ++ R++ R Q AQ+ IQ WRV + + ++ + + I++Q +G QR+ F K S LQ +WR + + L L+ ++ ++SA IQ+ WRM+QAR S++R + A + +Q Y+R + R R+LE S A + W R V R +R I+ ++ A LV Q WR Y R +R QA + IQ FR C +R L + +ALR LA+++IQ +R G RQ YI + +++ +Q+ R + R ++ S+++ IQ A+R + + + + L Q K ++ +MR RR+F + + +A+ IQS +RG ++ + + + IR+QAL + ++R ++++++A I+QR +R L L + + + S I IQ R ++A + L L + A IQ + + W +R+ ++ +R A Q+ YR Q+ + + + K
Sbjct: 2231 VQSAWRRHQAKKSLEMLKKER-VNKSAVVIQKFMRGRLCRKGFL---------TSKQAAVTIQKQWRMKLAQKFLVCLRTQKKTMAATVIQKHVRGRLCRREIEGLRGSALILQKLWRA-KKAREVVESLRAERQKEAAVLVQSVVRCASDRRKFLRL---------KRAAVCVQTQWRCVLAQREFMRLRLERQTHAAVVIQKNFHRFKAKKELYALRCAAVVIQKLWRAR------QARLELRKLRGQQKDRAALILQKHARGFLCRKNLQRSQMAAQK---------IQGLWRVCLARRELLRLRDQRRKSATIIIQKMFRGLQQRQAFAKIKGSVITLQSAWRVVR-ARRLFRKLREEKENKSALCIQSNWRMFQARHSFIRQRQAAVLMQCYWRGFLTR------RQLEKSQEAAMVIQCWYRACVAARHQRLEFIEKKHLAELV-QKMWRGYLARRNYQRERQAAIVIQAHFR------CFRRRL-KFLALR-------------LASVIIQRGYRNYRLGKQTRQEYIAITQAACTLQRWYRKCLELRHAQQISSAIK-IQAAFRAYKTRQMVTTKRNAALVIQM--KFRAHLQMREERRKFLE---------QKQAAVTIQSCFRGYREQVMYKNILTSAIRIQALERKRQDRKRFLALKQAAVILQRRYRAKML--GLVFREAFLSIRSSVIIIQ---RFYRAVKVGEQLKELLDTQRAAAIKIQSTYRGWSLRQDYLMLRAACVCCQRRYRAVQLGRSVRQEMK 2924 HSP 3 Score: 162.54 bits (410), Expect = 1.434e-36 Identity = 235/862 (27.26%), Postives = 398/862 (46.17%), Query Frame = 0
Query: 5 LQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKT-----ASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWK-------------------GCLFQKHLNE---RIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSAT-LIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKW-----AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA--------------QEELEHCS----ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKF-----------VQSLAHHLKWKR---------MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERK--LE-SLAATTIQSAWR--RNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR-KFIQRCCLQRCLSERI----------ALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALI------------------------KRL-EEQSEMRLRHQWATKIQSLWRMRMAR---REFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
L+ S I+Q+ WR + +E L ER+ + A +QS + R++ LR LKR +A +Q+ W+ + + +F L+ A+VV+Q +F + KA++ ++ AA VI K W+ + QKH R +L +A KIQG W++ R+ LR+ ++ SAT +IQ +R +R+AF ++ S + +QS +R A++ F ++ +A IQ +WR + Q H I+ R Q+A +Q YWR +++RR + Q A + LE A L+Q WR ++ + Y++ R +AIV+QA + + +R +F + + ++ ++QR +R ++ Q+ +W R SA +IQ +R ++ RQ +NA L IQ +R+H L + ER+ LE AA TIQS +R R QV + + +A+ IQ+ R+ Q+R QA V +QR +R K + + LS R A++ Q + +++ AAI IQS +RGW+ RQ Y+ LR + + Q++ R G VR++ + + RVIQR WRR+ + +RL EEQ M+ + + K+ + R + AR ++F + E + +A+++Q +R + R K+ R + LQ L + +R R A +IQR WR L +H Q+++ +A+ IQ+++RM + RR Y A S + IQ ++M V K+FI ++ A IQ+ R Y
Sbjct: 2326 LRGSALILQKLWRAKKAREVVESLRAERQ-KEAAVLVQSVVRCASDRRKFLR-------LKR--AAVCVQTQWRCVLAQREFMRLRLERQTHAAVVIQKNFHRFKAKKELYALRCAAVVIQKLWRARQARLELRKLRGQQKDRAALILQKHARGFLCRKNLQRSQMAAQKIQGLWRVCLARRELLRLRDQRRK-----SATIIIQKMFRGLQQRQAFAKIKGSVITLQSAWRVVRARRLFRKLREEKENKSALCIQSNWRMF---QARHSFIRQR---QAAVLMQCYWRGFLTRRQLEKSQEAAMVIQCWYRACVAARHQRLEFIEKKHLAELVQKMWRGYLARRNYQRERQAAIVIQAHFRCFRRRLKFLALRLASVIIQRGYRNYRLGKQTRQEYIAITQAACTLQRWYRKCLELRHAQQISSAIKIQAAFRAYKTRQMVTTKRNAALVIQMKFRAH---LQMREERRKFLEQKQAAVTIQSCFRGYREQV------MYKNILTSAIRIQALERKRQDRKRFLALKQAAVILQRRYRAKMLGLVFREAFLSIRSSVIIIQRFYRAVKVGEQLKELLDTQRAAAIKIQSTYRGWSLRQDYLMLRAACVCCQRRYRAVQLGRSVRQEMKHRCVATRVIQREWRRYLCVREAKRELEERREEVRRESQRQQEAERLAEEQRLMQEKAEDERKVFEMQRCQAARVIQKQFVLYRQKLCSERREKAAVMVQKCFRAYLVRCKYQETRNKLLFLQRLIRGFAVRRDFERQRLVAVLIQRWWRATLLAKHCR--QEFESSRDAAVRIQTMYRMIRQRREY------ALSLQRV-TKIQACVRMHVEHKRFIHVKCATIAIQRSLRSY 3148 HSP 4 Score: 134.035 bits (336), Expect = 7.751e-28 Identity = 178/639 (27.86%), Postives = 293/639 (45.85%), Query Frame = 0
Query: 173 RQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSW-------RHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWR---VWIQLKAYKQMRC--SAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR---LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAW------RQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRK--------SSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWR------------------RFALIKRL-----EEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQ------RAWRRHRL----IRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQV 749
R +A +Q WR K HLR L RK S AAT IQR+W R + + +R+ + + ++AT +Q + R RR ++R + +A +Q+ WR L+ K+ R SA+V+Q ++G + R+ F + K++A +Q+ W R K Q L+ ++ +AT IQ R R+ + + L +QK +R+ AR + +AER+ E AA +QS R RR+ R+ AA+ +Q+ W R++ RL LER+ A V IQ+ F +F + E ALR AA++IQ WR RQ + LRK +++++QK RG++ R++ +RS+ + + IQ WR +I+++ + Q+ +++ T +QS WR+ ARR F +++ EE +N SA+ IQS+WR R F+R R+ + +Q + + +R+L +E+A +IQ A R RL +HLAEL +Q +WR + ARR+Y+ A IQ + + R KF+ +R A +IQ+ YR Y++
Sbjct: 2129 RALAAVRLQCAWRRFRACKMLAHLRQEKLAKAELERKAS----------AATTIQRTWRASMIRRREAKVKEMEKKRVIYEMQQKAATTVQRHVRGLQCRREFVRSKQ---------AAVCVQSAWRRHQAKKSLEMLKKERVNKSAVVIQKFMRGRLCRKGFLTSKQAAVTIQKQW-RMKLAQKFLVCLRTQKKTMAATVIQKHVRGRLCRREIEGLRGSALILQKLWRAKKAREVVESLRAERQKE--AAVLVQSVVRCASDRRKFLRL----KRAAVCVQTQWRCVLAQREFM-RLRLERQTHAAVVIQKNFHRF-------KAKKELYALR-------------CAAVVIQKLWRA---RQARLELRKLRGQQKDRAALILQKHARGFLCRKNLQRSQMAAQKIQGLWRVCLARRELLRLRDQRRKSATIIIQKMFRGLQQRQAFAKIKGSVIT-LQSAWRVVRARRLFRKLR----EEKENKSALCIQSNWRMFQARHSFIRQRQAAVLMQCYWRGFLTRRQLEKSQEAAMVIQCWYRACVAARHQRLEFIEKKHLAEL------------VQKMWRGYLARRNYQR-------ERQAAIVIQAHFRCFRRRLKFLALRLASVIIQRGYRNYRL 2693 HSP 5 Score: 106.686 bits (265), Expect = 1.958e-19 Identity = 137/487 (28.13%), Postives = 224/487 (46.00%), Query Frame = 0
Query: 333 LQRSWRRFKFVQSLAH-------HLKWKRMHQSATRIQTQWR-------------MWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTR-NEAALVIQSAWRQYQNRLCLERRI---QACVRIQRGFR-KFIQR--CCL---QRCLSERIALRH------------------------------EAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDY-----ERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKAC----IAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR 750
LQ +WRRF+ + LAH + +R +AT IQ WR M + R Y Q A +Q++ R R F ++ AA +QSAWRR+Q ++ + + + R N++A+VIQ R RLC + + QA V IQ+ +R K Q+ CL ++ ++ + +H E E E + AA+L+QS R + R++++ L+++++ VQ Q R + +R++ ER + VIQ+ + RF K L LR A IQ LWR R AR E +++ + K+ +A+++Q H RG + R R + ++Q L + C R R+SA II ++ R L + Q + + S IT+QS WR+ +ARR +R L + IQ + +M+ R FIR R+A ++Q ++RG+ R
Sbjct: 2136 LQCAWRRFRACKMLAHLRQEKLAKAELERKASAATTIQRTWRASMIRRREAKVKEMEKKRVIYEMQQKAATTVQRHVRGLQCRREFVRSKQ----AAVCVQSAWRRHQAKKSLEMLKKERVNKSAVVIQKFMR---GRLCRKGFLTSKQAAVTIQKQWRMKLAQKFLVCLRTQKKTMAATVIQKHVRGRLCRREIEGLRGSALILQKLWRAKKAREVVESLRAERQKEAAVLVQSVVRCASDRRKFLRLKRAAVCVQTQWRCVLAQREFMRLRLERQTHAAVVIQKNFHRFKAKKEL-----YALRC-AAVVIQKLWRARQARLELRKLRG----QQKDRAALILQKHARGFLCRKNLQRSQMAAQKIQGLWRVCLARRELLRLRDQRRKSATIII-----QKMFRGLQQRQAFAKIKGSVITLQSAWRVVRARRLFRKLRE--EKENKSALCIQSNWRMFQARHSFIRQRQAAVLMQCYWRGFLTR 2598 HSP 6 Score: 80.1073 bits (196), Expect = 2.966e-11 Identity = 125/484 (25.83%), Postives = 201/484 (41.53%), Query Frame = 0
Query: 337 WRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR--------ERQRII-QTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA---------LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRK-----SSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMR-----ESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIR----------------------------IRRAVTVIQKHYRGYQVRTAFKSDCKIKQTAL 764
W R Q AH +A R+Q WR ++A C + + +A+ AE + ++ AATTIQ WR + +RR E++R+I + + +AA +Q R Q R R QA V +Q +R+ + L+ ER+ +R + + S+ AA+ IQ WR ++ + LR ++ ++QK VRG + RR+ E R S ALI +Q LWR + AR ++A E + +A+L+QS R R KFLRL+R + +Q + +AQR + +R +A +IQ+ + R + + L L+ +A+ IQ LWR +AR R L + A +Q+ + ++ RK R + A +IQK +RG Q R AF KIK + +
Sbjct: 2116 WIRPLLAQRFAHQRAL-----AAVRLQCAWRRFRA----------CKMLAHLRQEKLAK----AELERKASAATTIQRTWRASMIRRREAKVKEMEKKRVIYEMQQKAATTVQRHVRGLQCRREFVRSKQAAVCVQSAWRRHQAKKSLEMLKKERVNKSAVVIQKFMRGRLCRKGFLTSKQ-AAVTIQKQWRMKLAQKFLVCLRTQKKTMAATVIQKHVRGRLCRREIEGLRGS-----------ALI------------------LQKLWRAKKAREVVESLRA----ERQKEAAVLVQSVVRCASDRRKFLRLKRAAVCVQTQWRCVLAQREFMRLRLERQTHAAVVIQKNFHRFKAKKELYALR------CAAVVIQKLWRARQARLELRKLR--GQQKDRAALILQKHARGFLCRKNLQRSQMAAQKIQGLWRVCLARRELLRLRDQRRKSATIIIQKMFRGLQQRQAF---AKIKGSVI 2535 HSP 7 Score: 76.6406 bits (187), Expect = 3.002e-10 Identity = 105/364 (28.85%), Postives = 167/364 (45.88%), Query Frame = 0
Query: 432 RNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQR-------------YIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEE-------------QSEMRLR---------HQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMR-----ESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHL-----THLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR 750
R EAA+ IQ R + +R A VR+Q +R+F R C + L+ LR E +A E ++ AA IQ WR R+R Y +K++ VQ+ VRG RR++ RS+ + +Q AWRR K LE Q MR R Q A IQ WRM++A++ ++ + K +A +IQ H RG + R + LR + + LQ L +A A+ + S+R E+A ++Q ++R ++ +K+ + ++A+ +Q+ WR A+R + L TH A IQ++ + +K+ +R A VIQK +R Q R
Sbjct: 2106 RIEAAVKIQQWIRPLLAQRFAHQRALAAVRLQCAWRRF--RAC--KMLAH---LRQEKLAKAELERKASAATTIQRTWRASMIRRREAKVKEMEKKRVIYEMQQKAATTVQRHVRGLQCRREFVRSKQAAVCVQSAWRRHQAKKSLEMLKKERVNKSAVVIQKFMRGRLCRKGFLTSKQAAVTIQKQWRMKLAQKFLVCLRT----QKKTMAATVIQKHVRGRLCRREIEGLRGSALILQKLWRAKKAREVVESLRAERQKEAAVLVQ------SVVRCASDRRKFLRLKRAAVCVQTQWRCVLAQREFMRLRLERQTH-------AAVVIQKNFHRFKAKKELYALRCAAVVIQKLWRARQAR 2445
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|960967995|ref|XP_014798831.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein [Calidris pugnax]) HSP 1 Score: 253.447 bits (646), Expect = 2.336e-65 Identity = 312/1146 (27.23%), Postives = 537/1146 (46.86%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFR----QTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQE-------------ELRQYSA-----TLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFV-QHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATR-----IQTQWRMWQARQSYLRTQNACLAIQKYYRS-HVARLAFQAERKLESLAATTIQSAWRRNQVRR-------------------ERQRIIQTRN----------------------EAALVIQSAWR-----QYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEA---QERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQ-----KQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRE------------SARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWR--MHKAR--RHYRHLTHLA-------ASAEMAGATIQRSMQMWVV---RKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLWLLA-SSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRP-SPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L+++ + +IQR +R L + + L A IQS ++ R+++ + +Q+AT+IQ+ + H + A++ ASV++Q H+R + R R+L M + V+ ++G + R L + +A IQ ++M+R + + R+ Q +R YSA T IQ +R RK + + + +Q F+ + ++R+ S+K AA + QR +R QH E + R ++ IQ+ +R R+S E H +A+ IQ+ +++ ++Y++MR +AIV+Q + VKG QR++F + K SA V+Q S+R K Q L K MH SA + IQ+ +R + R Y Q++ +AIQ++YR+ H ARL +AE + A IQSA R + R+ +R++ IQ R +AA+V+Q +R +YQ L+ R + + +Q R FI++ R I ++ + R W + + AA +IQ+ +RGW R+ Y + K++ ++Q KQ R W ++ + V IQR WR + ++ Q Q IQ ++R ARR+F Q +A+A I+IQ+H R G +Q K+ + R+ I+LQAL + + ++++ + SA IQRA+R H ++R LA+ Q S + IQ +R M + R R Y+ + L A IQR+++ ++ R+KF+ +T Q +RGY R K TA KI+ +R + AN+ + E+ KL NRTA+A++ L + + +++++ LK L+V+TR S CC+ + R + + L+R CNRS+P MD+I + V +N++KYE + + E A++ ++TL+++L IYR K+ D I+TKT LL +L+ S R +I ++P + +K H HR+ ++ +R N SF P +P + K + P W +R+D ++ DP A MV++ L +
Sbjct: 2241 FLSIKTAAIVIQRKYRATKLAKIQHQKYLS--FRNAAVIIQSAYRGFVVRKKIQ---------QMHQAATVIQATLRMHKTYISYKAVRLASVIIQQHYRAYREGKRVRERYLKMYNSVLVLQAAYRG------MKTRCLLKKRHEAALIIQRNYRMYREYRHYRRVQWATQLIQKRYRANNLKKIAVRHYSALKKAATCIQKAFRDRQARKRHQEMHCAAVVVQKNFKAFRERQRYLSLKAAALVFQRRYRALILSRQHTSEYLSLR---RATVCIQAVYRGIRVRKSI---------EHMHLAASTIQSAYKMHRTRRSYQRMRIAAIVIQNYYRSYVKGKNQRQKFLTMKNSALVIQASYRGMKERQKL------KIMHVSAIKAAAIMIQSMFRCQRTRTRYKLIQSSAVAIQRWYRACHRARLQ-KAEYSAQRRAIVIIQSAVRGMKARKIARRIRAARKIQSFLQMAVQRRKFIQLRTAAVTIRAYYLMHKAKSQYTNYKKAAVVLQRCYRSRLTVRYQRTTYLQTR-RNIIIVQARVRGFIEKKRFHRIKESTIKIQASYRGYKTRQWVK-KMRAAQVIQAWFRGWRARKEYASVVKATRVIQSHFKTKQQRTWFLKMKF-----CVLCIQRRWRATLTARMIQRQFLATKNLQAVCLIQKIYRGFKARRKFEQQKAAA---------IIIQNHLRAWQKGRLQLMKYNKTRKAVIKLQALVRGYLVRKKISEQKRLLYFAAAAYHHISAIKIQRAYRIHLILR-LAQKQ-----ISSVLIIQRWFRAKMQQKRFLRDYQRIIQLQRVIRGWLKHRNDAATVIQRNVRRFLACRQRRKFVV---GITKFQALWRGYSWR-------KTNDTA-------------KIKALRCSIEKANKKSREENKLCNRTAIAIEHLLKYKHLSYIIAALKHLEVSTRLSPLCCENM--AQSRAIFTIFVLIRSCNRSVPCMDVIRYSVQVLLNVSKYERTTQAVYE-AENSIDTLLDLLQIYRGKAGDKISEKGGSIFTKTCCLLAILSKDSKRALEIRSMPRTVSCIQSLYKLTAHKHRVDAERTLVKQRTNTLSATSFVPVTPLRIKTVS---RIKPDWVLRKDNMQEIVDPLQAILMVIDTLGI 3299 HSP 2 Score: 172.17 bits (435), Expect = 1.484e-39 Identity = 201/803 (25.03%), Postives = 363/803 (45.21%), Query Frame = 0
Query: 52 QELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHE---------------------RIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVW----IQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR-------------------------------RFKFVQSLAHHLK-------WKRMHQ------SATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREF-------AQIQA-------SALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHL---------------------AELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
Q R +K ++ ++ ++QS W+ ++ F LK + LQSH R+ + +R+ MK AA VI W++ +K M +A +Q ++ + R+ RI+ S IQS +R++ RK F +L+ +T++IQ+ + A+K + +++ A +QR +R +R L E R Q + L ++A +Q+ +RM R+SYL + +A +IQ +R + Q + + Q++ + + LQA +G+ R+ + + R+A +Q ++R R F + A L WK Q +AT+IQ +R + A + + R +A IQK+YR+ V + E + +Q+ WR VR+ IQ ++ A VIQS +R + ++L ++ QA + IQ+ FR + C+++ I LR +A A +++QS +RG T R++ L K++ ++Q + ++V++DYER R + V+QR +R + + E+Q + L+ + K+Q+++R RR+ IQA S + +AI+IQ +R G V+R K+L L+++ I LQA + ++ L ++ +SA +IQ +R H+ + ++ Y +M + + IQ+ +R K RR R L + A IQR + ++ RK F+ I+ A VIQ+ YR
Sbjct: 1505 QAAFRGMKARKLYRQTKAVCVVQSLWRMKKEKLLFLRLKKSVTTLQSHVRKYQQVKRYKEMKNAASVIQAWYRAHASRK--KAAASFQRMRLAAVVLQSAYRGMKARKE-ARILR---------SVIKIQSNYRAYIVRKRFKYLKDATVKIQAFVKMRQARKNYCALREATLYVQRRYRSHRHALQLKEDYRKLKGACIRIQAVVRGYLVRKQMQRLRETAVFLQARYRMRRDRQSYLNI---------YRAAVVIQKHYRAYKKQLCQRQEFLQVKKAVVCLQAACRGYKARKNLKLEYRAAVKIQTAFRAHAARTKYKAMVEASIVVQRWYRACKTGNRQRLNFFTTRAAVLSLQAAFRGWKVRKQIRRQCVAATKIQAAFRKFMALKKFRRMNHAVRTIQKHYRASVIGQKQRQEYIQLRNSVVRLQALWRGKTVRK----TIQKKHNLATVIQSYYRMHVHQLKYKKLRQATLVIQKYFRAY----CMKKT-QRAIYLRTKA-----------AVLVLQSAYRGMTVRKQLSKLNKAATIIQAAFKSYLVKKDYERLRFAAIVVQRRYRA-TIHTKCEKQKYLSLK-EATLKMQAMYRGVKVRRQIHCMHRAAVCIQATFKMHCMSVKYQAMRMAAIIIQRQYRAFCLGKVERKKYLELKKSVIILQAAYRGMKVRQNLKTLHQSAAVIQSYYRMHKQQKDFRKLLLATRQIQQWFRACKERDTQVYNYMIMKSATLRIQAAFRGMKTRRLLRTLNE-------SAALIQRRFRTFIQRKHFLSIKTAAIVIQRKYRA 2257 HSP 3 Score: 164.851 bits (416), Expect = 2.667e-37 Identity = 215/843 (25.50%), Postives = 388/843 (46.03%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLE---------ELILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHL-------NERIHLSLMNRSATKIQGYWKMWRGR------------QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQ-----HLHERIQFRLL---------------NQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKF------------VQSLAHHL----KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAE-RKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCL-QRCLSERIALRH-EAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
R+ +IQ WR Y L + L+ +I + IN A IQ W+ + +R LL K LE R++SAT+IQ++W+ + R+++ L+ V +QS R K+ A W Q HL +R + SA IQ ++ WR Q + R ++ R +A +IQS +R H + K +L ++ S ++IQ+ +R A++ + + IQ+ +R Y+ + +L +R +L ++ +QS WRM + +LR + S T +Q+ R + Q+K YK+M+ +A V+QA + R++ F+ + +A VLQ ++R K +QS ++K + + +IQ +M QAR++Y + A L +Q+ YRSH L + + RKL+ A IQ+ R VR++ QR+ E A+ +Q+ +R ++R +A V IQ+ +R + ++ C Q L + A+ +A R + ++L AA+ IQ+ +R R +Y + ++SI+VQ+ R G R ++ +R++V +Q A+R + + K++ Q ATKIQ+ +R MA ++F ++ N++ IQ H+R V QR ++++LR + +RLQAL + ++ + A +IQ +R H + L KYK + Q+ + IQ +R + ++ R + +A + + R M VRK+ ++ +A T+IQ ++ Y V+ ++
Sbjct: 1228 RAARLIQSVWRNYRLKRELKLSQERDRAARIIQKSAINFLSRRRFLKKVNAAVIIQKHWRRYLARMTLLNLKKTKLEESRSKSATVIQAYWRRYSARKRYLQLRYYVVFVQSRIRMVKS---------VAAYKRILWATVTIQNHLRASKLAKKDRQRYETLKSSALTIQSAFRRWRKHKIQQKIKATLVLQTYFRKWQSSKLAKRTKAALVIQSWYRMHRDLKHYLRVKQSVIKIQAWYRCQLAKRIYQEHRAKIVTIQQHYRAYKLGKTEREHYLQKRAAVVVLQAAFRGMKARKLYRQTKAVCVVQSLWRMKKEKLLFLRLKK---------SVTTLQSHVRKYQQVKRYKEMKNAASVIQAWYRAHASRKKAAASFQRMRLAAVVLQSAYRGMKARKEARILRSVIKIQSNYRAYIVRKRFKYLKDATVKIQAFVKMRQARKNYCALREATLYVQRRYRSHRHALQLKEDYRKLKG-ACIRIQAVVRGYLVRKQMQRL----RETAVFLQARYRMRRDRQSYLNIYRAAVVIQKHYRAYKKQLCQRQEFLQVKKAVVCLQAACRGYKARKNLKLEYRAAVKIQTAFRAHAARTKYKAMVEASIVVQRWYRACKTGNRQRLNFFTTRAAVLSLQAAFRGWKVRKQIRRQCVA------ATKIQAAFRKFMALKKFRRM---------NHAVRTIQKHYRASVIGQKQRQEYIQLRNSVVRLQALWRGKTVRKTIQKKHNLATVIQSYYRMH--VHQL----KYKKLRQATLVIQKYFRAYCMKKTQRAIYLRTKAAVLVLQSAYRGM---TVRKQLSKLNKAATIIQAAFKSYLVKKDYE 2023 HSP 4 Score: 147.517 bits (371), Expect = 5.353e-32 Identity = 199/815 (24.42%), Postives = 391/815 (47.98%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYS--LVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRS----YLRFQTEA--------------QEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWI----QRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTI--QSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRC--CLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKA----CIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQ---------------------KYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
YL + R+ +IQ+ +R Y L QR E L ++ + +Q+ + +++R+ L LE + +A IQ+ ++AH R ++ A+ AS+V+Q +R K R F T + A + ++G +K + + +ATKIQ ++ + + F R+ + + Y A++I +R+ ++ LR+S +R+Q+ +R + +K AT+IQ +R H+H+ ++++ L Q+ IQ Y+R + +++ YLR + Q + +AT+IQA ++ ++ K Y+++R +AIV+Q + + I +++++ S K + +Q +R K + + H MH++A IQ ++M Y + A + IQ+ YR+ L +K L + I Q+A+R +VR+ ++T +++A VIQS +R ++ + + + A +IQ+ FR +R + + LR +A R R L +A LIQ +R + QR+ ++ ++ ++I++Q++ R I + Y R++ +IQ A+R F + K++++ HQ AT IQ+ RM + + +A L ++++IQ H+R G R ++L++ + + LQA + C+ ++R E+A IIQR +R +R RH +Q Y + ++A IQ +R +AR+ ++ + H AA +Q++ + + R++++ ++ A V Q+ YR
Sbjct: 1730 YLNIYRAAVVIQKHYRAYKKQLCQRQEFL----QVKKAVVCLQAACRGYKARKN------LKLEYR---AAVKIQTAFRAHAARTKYKAMVEASIVVQRWYRACKTGNRQRLNFFTTRAAVLSLQAAFRGWKVRKQIRRQC------VAATKIQAAFRKFMALKKFRRMNHAVRTIQKHYRASVI-----GQKQRQEYIQLRNSVVRLQALWRGKTVRKTIQKKHNLATVIQSYYR-----MHVHQ-LKYKKLRQATLVIQKYFRAYCMKKTQRAIYLRTKAAVLVLQSAYRGMTVRKQLSKLNKAATIIQAAFKSYLVKKDYERLRFAAIVVQRRYRATIHTKCEKQKYLSLKEATLKMQAMYRGVKVRRQI--HC----MHRAAVCIQATFKMHCMSVKYQAMRMAAIIIQRQYRAFC--LGKVERKKYLELKKSVIILQAAYRGMKVRQN----LKTLHQSAAVIQSYYRMHKQQKDFRKLLLATRQIQQWFRACKERDTQVYNYMIMKSATLRIQAAFRGMKTRRLLRTLNESAALIQRRFRTFIQRKHFLSIKTAAIVIQRKYRATKLAKIQHQKYLSFRNAAVIIQSAYRGFVVRKKIQQM------HQAATVIQATLRM---HKTYISYKAVRL------ASVIIQQHYRAYREGKRVRERYLKMYNSVLVLQAAYRGMKTRCLLKKR----HEAALIIQRNYRMYREYRHYRRVQWATQLIQKRYRANNLKKIAVRHYSALKKAATCIQKAFRDRQARKRHQEM-HCAA------VVVQKNFKAFRERQRYLSLKAAALVFQRRYRA 2476 HSP 5 Score: 83.5741 bits (205), Expect = 2.444e-12 Identity = 114/443 (25.73%), Postives = 202/443 (45.60%), Query Frame = 0
Query: 405 ESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR------------------------GWIVRRD---YERSRSSVRVIQRA---WRRFALIKRLE------------EQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNY--------------SAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWR--RHRL---------------IRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAE---MAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK--SDCKIKQTALL 765
E+ AA IQS WR +++RE ++ Q R+ AA +IQ + + +R +++ A V IQ+ +R+++ R L + L+ E ESRS +A +IQ++WR ++ R+RY+ LR + VQ ++R + ++D YE +SS IQ A WR+ + ++++ + S++ R + A IQS +RM + + +++ S ++ Y + IQ H+R G +R +L+ R + LQA + A R+L ++ ++Q WR + +L +R ++++YK M +A IQ+ +R H +R+ AAS + +A +Q + + RK+ RI R+V IQ +YR Y VR FK D +K A +
Sbjct: 1226 ETRAARLIQSVWRNYRLKRE-LKLSQERDRAARIIQKSAINFLSRRRFLKKVNAAVIIQKHWRRYLARMTL-------LNLKKTKLE----ESRSKSATVIQAYWRRYSARKRYLQLRYYVVFVQSRIRMVKSVAAYKRILWATVTIQNHLRASKLAKKDRQRYETLKSSALTIQSAFRRWRKHKIQQKIKATLVLQTYFRKWQSSKLAKRTKAALVIQSWYRMHRDLKHYLRVKQSVIKIQAWYRCQLAKRIYQEHRAKIVTIQQHYRAYKLGKTEREHYLQKRAAVVVLQAAFRGMKA-RKLYRQTKAVCVVQSLWRMKKEKLLFLRLKKSVTTLQSHVRKYQQVKRYKEMKNAASVIQAWYRAHASRK------KAAASFQRMRLAAVVLQSAYRGMKARKE-ARILRSVIKIQSNYRAYIVRKRFKYLKDATVKIQAFV 1648
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|930237259|ref|XP_014163570.1| (PREDICTED: LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein [Geospiza fortis]) HSP 1 Score: 251.906 bits (642), Expect = 6.394e-65 Identity = 296/1142 (25.92%), Postives = 528/1142 (46.23%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTK----ARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYR---------------------FVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-------------------ERQRIIQTRNEAALVIQSAW--------------------RQYQNRLCLERRIQA-------CVRIQRGFRKFIQRCCLQRCLSERI---ALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMH-------KARRHYRHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLWLLA-SSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERG---RRRNNYLPNSFRPSPAQAKP-KMPKLS-LCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
YL+L + IIQ ++R + + ++++++ +Q AT IQ+ +MH+ I S ++ AL+ ASV++Q H+R + R+++L + + V+ ++G + R L + +A IQ ++M+R + R+ Q++A LIQ ++R+H RK + L+ + IQ FR+ +K+ M AAT++Q++++ +R V +++ L ++A +IQ+ +R RRS H +A+ IQA +R+ +AY+ MR +A+++Q + +KG QR+++ + K S V+Q ++R + Q L L + +A IQ+ +R W+AR Y +++ +A+Q++YRS + A +A+ + A IQSA+R + R+ +R++ IQ R AA+ +QS + R Y++ L ++ + A V +Q R +IQ+ + I A + R W S+ AA +IQ+ +RG R+ YI + ++++++Q+ R ++ + + +S IQR WR +RL +Q HQ A IQ+ +R ARR+F Q +A +A++IQ H R G +Q K+ + RR I+LQA + + ++++ ++ R+ IQRA+R H I+ LA+ Q S + IQS +R + R L H + A A IQR+ + ++ ++ R+ + Q +RGY R K+ TA K +R + ANE + E+ KLGNRTA+A+D L + + ++++L LK L+V TR S CC+ + R + + L+R CNRS+P MD+I + V +N++KYE + + E A++ ++TL+++L +YR K+ D I+TKT LL +L+ S R +I +P + +K R H ER ++ N L S S P ++ +S + P W +R+D ++ DP A MV++ L +
Sbjct: 2192 YLSLLNATVIIQSAYRGFVVRKKMQQM------HQAATVIQAMVRMHK-----------------------IYSSYQ---------ALRLASVIIQQHYRAYREGKHERQKYLKLYNSVLVLQAAYRG------MKTRCFLKRQHEAALTIQRNYRMYRQYCHYRRV---------QWAAQLIQRRYRAHRLRKIAVEHYASLKKAAACIQRAFREMRVRKQQREMHCAATVLQKNFKAFRERQRYLSLKAATLVFQRRYRALVLARQHALEYHSLRRAAIRIQAVYRGVRVRRSLKHM---------HSAASKIQAAYRMLRDRRAYQNMRVAAVLIQNYYRSYLKGKNQRKKYLTMKNSVLVIQAAYRGMRARQEL-KLLHVSAVQSAAVTIQSAFRCWRARTRYALLRSSAVAVQRWYRSCLRARAQKAQYLAQRQAIVVIQSAFRAMKARKTAKQLRAARKIQSFLQMALQRRKYIQLR-AAAVTLQSYYLMHKCKSQYMSYRRAAVVLQRHYRSHLTVKHQRMAYLQTRRNIVLVQATVRGYIQKTRFHKMKESTIKIQAAYRGYKARQWV-SKMRAARVIQAWFRGHKARKEYISVLRATLVIQRHFRARQLQTRFLQMKSCALTIQRFWRATCAARRLRQQFLATRSHQAACLIQNAYRGFKARRKFVQQKA---------AAVIIQKHLRAWQEGRLQFMKYNKTRRAVIKLQAFIRGYLVRKKISEQKQKKRLLYFTAAAYHHISAIKIQRAYRLHLTIK-LAQTQ-----ISSVLIIQSWFRAQAQRRRFVRDRGRVVQLQHAVRAWLSRRHRAAAVIQRNARAFLAHRRRRRLAVGIVKFQALWRGYSWR-------KMTDTA-------------KTRALRHSLVKANEKSREENKLGNRTAIAIDHLLKYKHLSYILAALKHLEVATRLSPLCCENM--AQSRAIFSVFLLIRSCNRSVPCMDVIRYSVQVLLNVSKYERTTRAVYE-AENSIDTLLDLLQMYRGKAGDKVSEKGGSIFTKTCCLLAILSKDSKRALEIRGMPRTVPCIQSLYKLTARKHRMDAERTLVKQKTNTALAGS---SSVPVTPLRIKTVSRIKPEWVLRKDNMQEVVDPLQAIVMVMDTLGI 3227 HSP 2 Score: 175.637 bits (444), Expect = 1.256e-40 Identity = 215/846 (25.41%), Postives = 393/846 (46.45%), Query Frame = 0
Query: 12 IQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNR---SATKIQ-GYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRR-------------SYLRFQTEAQEELE-HCSATLIQAQWRVWIQLKAYKQ----MRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR-------------------------------RFKFVQSLAHHLK-------WK------RMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAW----------RRFALIKRLEEQSE-----MRLR------HQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHL----------------------AELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
IQ+ +R Y L + E L+++ A +Q+ ++ ++R EL R+ K +A +IQS W+ ++++F LK + LQSH R+ + +R+ +K AA VI ++ H+ + + R +A +Q Y M RQA + LR S IQS +R++ RK F LR +T++IQ+ + +KR+ +++ A +QR +R R E +R L + +IQ+ R ++ R+ + R + + Q L + +AT+IQ ++ + + ++Q +R +A+ LQA +G+ R++ + + R+A +Q ++R R F+ + A L W+ R H +AT+IQ+ +R + A + + ++A L IQ++YR+ V L + R+ L AA +Q+ WR VR+ IQ ++ A +IQS +R + N++ ++ QA + IQ+ +R + C+++ +RA A +++QS +RG T R++ L K++ +Q + ++V+++YER RS+ IQR + +R+ +KR+ Q + +R+R HQ A IQ+ ++M R++ ++ +A+ + Y A + G VQR K+L L+++ I LQA + ++ L +M +SA IIQ +R H+ R E+ Y +M + + IQ+ +R K RR R + + IQR + + RK+F+ I+ A VIQ+ YR
Sbjct: 1400 IQQYYRAYKLGKGERESYLQKRA--AAIVLQAAFRGMKAR-ELYRQAK---------AACVIQSLWRMKREKQRFLQLKKSVTTLQSHVRKYQQVKRYKEIKNAASVIQTRYRA-----HVATKKSAAAFRRVRLAAIVLQSAYRGMQARRQACI---------LR--SVIKIQSSFRAYVARKRFKTLRDATVKIQALAKMRQVRKRYCALREAVLYVQRRYRSQRCALQFKE--DYRKLKRGCIRIQALVRGYLVRKQMQRWRKAAILLQACYRMKRDRQRYLSIYGAATVIQQRYHACRKTQCHRQEFLRVRRAAVCLQAAYRGYKTRKKLKLECRAAIKIQAAFRAHAARVKHKAMVQASIVIQRWYRNCKGGKRQRLNFLMTRAAVLSLQAAFRGWRVRKQIQRQHVAATKIQSTFRKFMAVKKFRLVKHAVLTIQRHYRAKV--LGHRQRREYVQLRNAAVRLQALWRGKAVRKN----IQKQHHLATIIQSYYRMHINQIKYKKLRQATLVIQKYYRAY----CMKKT------------QRAVYLKTKAAVLVLQSAYRGMTARRQLNKLNKAATTIQAAFKSYLVKKEYERLRSAAVAIQRRYCAVTHAKCQRQRYLSLKRVTVQVQAIYRGVRVRRQVQCMHQAAVCIQATFKMYCMSRKYQSMRMAAIRIQRQYRAFCL-----GKVQRKKYLELKKSVIILQAACRGTKVRQGLKTMHQSAAIIQSYYRMHKQQRDFENPLLLATRQIQQWFRACKKRDTEVHNYMIMKNAVVHIQAAFRGMKTRRLIRTMNE-------SAVIIQRRFRTVLERKRFLSIKSAAIVIQRKYRA 2181 HSP 3 Score: 155.992 bits (393), Expect = 1.555e-34 Identity = 218/882 (24.72%), Postives = 410/882 (46.49%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLA-------------------------------------LELKR-----NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTK----ARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAF--LRIMA---------------DAQEELRQYSATLI-QSQWRSHSERKAFLHLRH-STLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRF----VQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRI-IQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQ-RCCLQRCLSERIAL-----RHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR--------------LIRHLAELQ---KYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQ-VRTAFKSDCKIKQTAL-LPDFPINEELSKKIEEVRQK 784
YL L++SV I+Q + R + Q L+ + +Q A IQS+++MH+ +++ L LA ++ +R N+SA +IQ ++ ++R++F ++K+A++V+Q +R +K R+++L++ A +I ++G + +K + + M+++AT IQ +M + ++ LR+ + + Q+ L+ Y++ L+ Q+ +R R FL +H + L IQ +R + + ++WAA +IQR +R +R V+H + L ++A IQ R++ + Q+ HC+AT++Q ++ + + + Y ++ + +V Q + + + RQ + S +R+A +Q +R + +SL H MH +A++IQ +RM + R++Y + A + IQ YYRS++ + + + IQ+A+R + R+E + + + AA+ IQSA+R ++ R + V +QR +R ++ R + L++R A+ A + T + AA IQS + QR++YI LR +++ +Q + Y R + V+QR +R S + ++HQ +Q+ RR +L+Q+ RG +Q+ +F +++ + I++QA + A R+ VS +AR+IQ +R H+ + RH Q ++ M A+TIQ WR A R R LA + A IQ + + + R+KF++ + A +IQKH R +Q R F K ++ + L F + KKI E +QK
Sbjct: 2045 YLELKKSVIILQAACRGTKVRQGLKTM------HQSAAIIQSYYRMHKQQRDFENPLLLATRQIQQWFRACKKRDTEVHNYMIMKNAVVHIQAAFRGMKTRRLIRTMNESAVIIQRRFRTVLERKRFLSIKSAAIVIQRKYRASKLANIQRQKYLSLLNATVIIQSAYRGFVVRKKMQQ------MHQAATVIQAMVRMHKIYSSYQALRLASVIIQQHYRAYREGKHERQKYLKLYNSVLVLQAAYRGMKTR-CFLKRQHEAALTIQRNYRMYRQYCHYRRVQWAAQLIQRRYRAHRLRKIAVEH------YASLKKAAACIQ---------RAFREMRVRKQQREMHCAATVLQKNFKAFRERQRYLSLKAATLVFQRRYRALVLARQHALEYHSLRRAAIRIQAVYRGVRVRRSLKH------MHSAASKIQAAYRMLRDRRAYQNMRVAAVLIQNYYRSYLKGKNQRKKYLTMKNSVLVIQAAYRGMRARQELKLLHVSAVQSAAVTIQSAFRCWRARTRYALLRSSAVAVQRWYRSCLRARAQKAQYLAQRQAIVVIQSAFRAMKARKTAKQLRAARKIQSFLQMALQRRKYIQLRAAAVTLQSYYLMHKCKSQYMSYRRAAVVLQRHYR-----------SHLTVKHQRMAYLQT-------RRNI----------------VLVQATVRGYIQKTRFHKMKESTIKIQAAYRGYKA-RQWVSKMRAARVIQAWFRGHKARKEYISVLRATLVIQRHFRARQLQTRFLQMKSCALTIQRFWRATCAARRLRQ-QFLATRSHQAACLIQNAYRGFKARRKFVQQKAAAVIIQKHLRAWQEGRLQFMKYNKTRRAVIKLQAFIRGYLVRKKISEQKQK 2856 HSP 4 Score: 150.599 bits (379), Expect = 7.409e-33 Identity = 213/858 (24.83%), Postives = 389/858 (45.34%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLE---------ELILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLN-------ERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMA------------DAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQ-----HLHER-------IQFRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHC--------------SATLIQAQWRVWIQLK----AYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNR----------LCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWR---MHKARR---------------HYRHLTHLAASAEM--AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHY 744
R+ +IQ +WR+Y L + L+ +I + +N A IQ W+ + +R+ L K LE RN+SAT+IQ++W+ + R ++ L+ + +Q+ R K+ A W Q+HL +R ++ SA IQ ++ WR + +I A ++ R+ +A +IQS +R H + K +LH++ + ++IQ+ +R A++ + + IQ+ +R Y+ + +L +R FR + ++A IQS WRM ++ +L+ + H +A++IQ ++R + K A++++R +AIVLQ+ +G RRQ RS +Q S+R + ++K + + +IQ +M Q R+ Y + A L +Q+ YRS L F+ + + IQ+ R VR++ QR +AA+++Q+ +R ++R +++R AC + Q ++F++ R A+ +A R + + L AAI IQ+ +R R ++ + ++SI++Q+ R G R ++ +R++V +Q A+R + + K+++ Q H ATKIQS +R MA ++F L ++ + IQ H+R V QR ++++LR +RLQAL + ++ + A IIQ +R H I + KYK + Q+ + IQ +R M K +R YR +T ++ A TIQ + + ++V+K++ R+R A IQ+ Y
Sbjct: 1151 RAARLIQAAWRKYRLKRELKLFQERDRAARIIQKSAMNFLACRRILRRENAAIFIQKHWRGYLARRTLFNLKKAKLEEARNKSATVIQAYWRRYSARRRYLQLRHCVIFVQARIRMVKS---------VAAYKQIVWATVTIQRHLRAAKLARIDRQRYQILKSSALTIQSAFRRWRKYKIQQKIKAALVIQSYFQKWQSSKLAKRRRAALVIQSWYRMHRDLKQYLHVKRNVIKIQAWYRCQLARRVYQEHRAKIVTIQQYYRAYKLGKGERESYLQKRAAAIVLQAAFRGMKARELYRQAKAACVIQSLWRMKREKQRFLQLKKSVTTLQSHVRKYQQVKRYKEIKNAASVIQTRYRAHVATKKSAAAFRRVRLAAIVLQSAYRGMQARRQ-ACILRSVIKIQSSFRAY------VARKRFKTLRDATVKIQALAKMRQVRKRYCALREAVLYVQRRYRSQRCALQFKEDYRKLKRGCIRIQALVRGYLVRKQMQRW----RKAAILLQACYRMKRDRQRYLSIYGAATVIQQRYHACRKTQCHRQEFLR--------VRRAAVCLQAAYRGYKTRKKLKLECRAAIKIQAAFRAHAARVKHKAMVQASIVIQRWYRNCKGGKRQRLNFLMTRAAVLSLQAAFRGWRVRKQIQRQ------HVAATKIQSTFRKFMAVKKF---------RLVKHAVLTIQRHYRAKVLGHRQRREYVQLRNAAVRLQALWRGKAVRKNIQKQHHLATIIQSYYRMH--INQI----KYKKLRQATLVIQKYYRAYCMKKTQRAVYLKTKAAVLVLQSAYRGMTARRQLNKLNKAATTIQAAFKSYLVKKEYERLRSAAVAIQRRY 1959 HSP 5 Score: 139.043 bits (349), Expect = 2.445e-29 Identity = 186/692 (26.88%), Postives = 300/692 (43.35%), Query Frame = 0
Query: 133 NERIHLSLMNRSATKIQGYWKMWRGRQ------------AFLRIMADAQEELRQYS--ATLIQSQWRSHS---ERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLL--------NQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGW----IQRRQFESQKRSARVLQ---RSWRRFKFVQSLAHHL-------KWK-----RMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRL---------------IRHLAELQKYKVMTQ------SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCK 758
NE+ + L+N + + + G M +L + +LRQ + A LIQ+ WR + E K F + IQ + A +R + AA IQ+ WR Y L R F L N+SAT IQ+YWR + +RR YL +L HC +QA+ R+ + AYKQ+ + + +Q ++ I R++++ K SA +Q R WR++K Q + L KW+ + ++A IQ+ +RM + + YL + + IQ +YR +AR +Q R TIQ +R ++ + ER+ +Q R AA+V+Q+A+R + R + ACV IQS WR ++QR++ L+KS +Q VR + + Y+ +++ VIQ +R K+ + R A +QS +R ARR QA L S I IQS +R V R +F LR +++QALAK ++R ++RE+ +QR +R R IR A ++ Y V Q +AI +Q+ +RM + R+ Y + +A + + R++F+R+RRA +Q YRGY+ R K +C+
Sbjct: 1095 NEKQNFQLINAAVSDLGGIPAMIHHADMSNTIPDEKVVITYLSFLCSRLLDLRQETRAARLIQAAWRKYRLKRELKLFQERDRAARIIQKSAMNFLACRRILRRENAAIFIQKHWRGY-----LARRTLFNLKKAKLEEARNKSATVIQAYWRRYSARRRYL--------QLRHC-VIFVQARIRMVKSVAAYKQIVWATVTIQRHLRAAKLARIDRQRYQILKSSALTIQSAFRRWRKYKIQQKIKAALVIQSYFQKWQSSKLAKRRRAALVIQSWYRMHRDLKQYLHVKRNVIKIQAWYRCQLARRVYQEHRA----KIVTIQQYYRAYKLGKGERESYLQKR-AAAIVLQAAFRGMKARELYRQAKAACV--------------------------------------------IQSLWRMKREKQRFLQLKKSVTTLQSHVRKYQQVKRYKEIKNAASVIQTRYRAHVATKK--SAAAFRRVRLAAIVLQSAYRGMQARR-----QACILR-----SVIKIQSSFRAYVARKRFKTLRDATVKIQALAKMRQVRKRYCALREAVLYVQRRYRSQRCALQFKEDYRKLKRGCIRIQALVRGYLVRKQMQRWRKAAILLQACYRMKRDRQRY---LSIYGAATVIQQRYHACRKTQCHRQEFLRVRRAAVCLQAAYRGYKTRKKLKLECR 1708 HSP 6 Score: 135.961 bits (341), Expect = 2.354e-28 Identity = 206/810 (25.43%), Postives = 378/810 (46.67%), Query Frame = 0
Query: 2 YLTLQRSVHIIQ---RSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQY-SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHC---SATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKG---------------WIQRRQFESQKRSARVLQRSWRRFKF----VQSLA-HHLKWKRMH---QSATRIQTQWRMWQARQSYLRTQNACLAIQKYY----RSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR--KFIQRCCLQRCLSERIALRHEAQERAW-----TESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSA------------------ILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHL-AELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
Y L+ S IQ R WR+Y + Q+++ ++ IQS+++ +S KLA KR ++A +IQS ++ H +Q+ +K + +Q+ +R ARR + + I ++++ K E L R+A + QA R M A+E RQ +A +IQS WR E++ FL L+ S +QS RK+ KR+ +K AA++IQ +R + V FR + +A +QS +R +RR + C S IQ+ +R ++ K +K +R + + +QA K ++QRR + SQ R A + +R+ K +Q+L +L K+M ++A +Q +RM + RQ YL A IQ+ Y ++ R F R+ AA +Q+A+R + R++ ++ AA+ IQ+A+R + R+ + +QA + IQR +R K +R L ++ L +A R W + + +AA IQS +R + +++ ++ + + +Q+ R ++ RR+Y + R++ +Q WR A+ K +++Q H AT IQS +RM + + ++ +++ + L K Y A +++QS +RG R + +L + +QA K+ + ++ +R +A IQR R+ + H + Q+Y + + + +Q+++R + RR + + A IQ + +M+ + +K+ +R A IQ+ YR +
Sbjct: 1300 YQILKSSALTIQSAFRRWRKYKIQQKIKAALV----------IQSYFQKWQSS-------KLA---KRRRAALVIQSWYRMHRDLKQYLHVKRNVIKIQAWYRCQLARRVYQEHRAKIVTIQQYYRAYKLGKGERESY---LQKRAAAIVL---------QAAFRGM-KARELYRQAKAACVIQSLWRMKREKQRFLQLKKSVTTLQSHVRKYQQVKRYKEIKNAASVIQTRYRAH--VATKKSAAAFRRVRLAAIVLQSAYRGMQARR-------------QACILRSVIKIQSSFRAYVARKRFKTLRDATVKIQALAKMRQVRKRYCALREAVLYVQRR-YRSQ-RCALQFKEDYRKLKRGCIRIQALVRGYLVRKQMQRWRKAAILLQACYRMKRDRQRYLSIYGAATVIQQRYHACRKTQCHRQEFLRVRR----AAVCLQAAYRGYKTRKK----LKLECRAAIKIQAAFRAHAARVKHKAMVQASIVIQRWYRNCKGGKRQRLNFLMTRAAVLSLQAAFRGWRVRKQIQRQHVAATKIQSTFRKFMAVKKFRLVKHAVLTIQRHYRAKVLGHRQRREYVQLRNAAVRLQALWRGKAVRKNIQKQ------HHLATIIQSYYRMHINQIKYKKLRQATLVIQKYYRAYCMKKTQRAVYLKTKAAVLVLQSAYRGMTARRQLNKLNKAATTIQAAFKSYLVKKEYERLRSAAVAIQR---RYCAVTHAKCQRQRYLSLKRVTVQVQAIYRGVRVRRQVQCM-------HQAAVCIQATFKMYCMSRKYQSMRMAAIRIQRQYRAF 2035 HSP 7 Score: 132.88 bits (333), Expect = 2.009e-27 Identity = 185/720 (25.69%), Postives = 326/720 (45.28%), Query Frame = 0
Query: 144 SATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMW------------MSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKF-----------------VQSLAHHLKWKRMH---QSATRIQTQWRMWQARQSYLR-----------------------TQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRE-------------------RQRIIQTRNEAALVIQ--SAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQ-----RCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQV----RGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMAR-REFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWR------RHRLIRHLA---------------ELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
+A IQ +W+ + R+ + EE R SAT+IQ+ WR +S R+ +L LRH + +Q+ R + + + WA IQR R + + +R ++++L SA IQS +R W + +SY + ++ +A +IQ+ +R+ LK Y ++ + I +QA + + RR ++ + +Q+ +R +K +Q+ +K + ++ ++A IQ+ WRM + +Q +L+ +NA IQ YR+HVA A + LAA +QSA+R Q RR+ R+R +T +A + IQ + RQ + R C R +A + +QR +R QRC LQ R L +R +R +A R + + + AAIL+Q+ +R RQRY+ + ++ ++Q++ + R+++ R R + +Q A+R + K+L +L + A KIQ+ +R AR + A +QAS I+IQ +R C QR FL R + LQA + ++++ +A IQ +R + RL++H + ++Y + +A+ +Q+LWR R++ + HLA IQ +M + + K+ ++R+A VIQK+YR Y
Sbjct: 1201 AAIFIQKHWRGYLARRTLFNLKKAKLEEARNKSATVIQAYWRRYSARRRYLQLRHCVIFVQARIRMVKSVAAYKQIVWATVTIQRHLRAAKLAR--IDRQRYQILKSSALTIQSAFRRWRKYKIQQKIKAALVIQSYFQKWQSSKLAKRRRAALVIQSWYRMHRDLKQYLHVKRNVIKIQAWYRCQLARRVYQEHRAKIVTIQQYYRAYKLGKGERESYLQKRAAAIVLQAAFRGMKARELYRQAKAACVIQSLWRMKREKQRFLQLKKSVTTLQSHVRKYQQVKRYKEIKNAASVIQTRYRAHVATKKSAAAFRRVRLAAIVLQSAYRGMQARRQACILRSVIKIQSSFRAYVARKR-FKTLRDATVKIQALAKMRQVRKRYCALR--EAVLYVQRRYRS--QRCALQFKEDYRKL-KRGCIRIQALVRGYLVRKQMQRWRKAAILLQACYRMKRDRQRYLSIYGAATVIQQRYHACRKTQCHRQEFLRVRRAAVCLQAAYRGYKTRKKL------KLECRAAIKIQAAFRAHAARVKHKAMVQAS----------IVIQRWYRNCKGGKRQRLNFLMTRAAVLSLQAAFRGWRVRKQIQRQHVAATKIQSTFRKFMAVKKFRLVKHAVLTIQRHYRAKVLGHRQRREYVQLRNAAVRLQALWRGKAVRKNIQKQHHLA-------TIIQSYYRMHINQIKYKKLRQATLVIQKYYRAY 1889 The following BLAST results are available for this feature:
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 4
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 22
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BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold1923_size24897:88..6266+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold1923_size24897-snap-gene-0.7 ID=maker-scaffold1923_size24897-snap-gene-0.7|Name=abnormal spindle-like microcephaly-associated protein homolog|organism=Tigriopus kingsejongensis|type=gene|length=6179bp|location=Sequence derived from alignment at scaffold1923_size24897:88..6266+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'abnormal spindle-like microcephaly-associated protein homolog' has the following synonyms
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