abnormal spindle-like microcephaly-associated protein homolog, maker-scaffold1923_size24897-snap-gene-0.7 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000008050 (supercontig:LSalAtl2s:LSalAtl2s479:220317:222350:-1 gene:EMLSAG00000008050 transcript:EMLSAT00000008050 description:"maker-LSalAtl2s479-snap-gene-2.31") HSP 1 Score: 156.377 bits (394), Expect = 6.114e-41 Identity = 131/485 (27.01%), Postives = 231/485 (47.63%), Query Frame = 0
Query: 482 RIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLR---KSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFA--QIQASALEELKNYSAILIQSHWRGCVQRGKFLRLR---RTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSEND-RCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLL----ASSNRVKKILTLPLNAKKLLESHKHYHRLH 953
R + E + R +S ++++IQ + R + Q ++ + LR + +MVQ VR ++ +++++R +S +++ + + IQS R A+++F +IQ KN S+++IQS RG +Q+ KF ++ R +++Q++ RR ++M++ ++ V+ Q +I H++ +A IQR+ + W+ RKKF + R V VIQ +RG++ R + N LS EVR ++ AN+ ATE+ KL NR + L LY + +A L+ I+ DLD +TR+S CCDQ++ D + V +LL+L+ RCN+S+PH+++IS +LD INL +YE +R+ + + +T +E L + V I+ K + L++L VKK T + L+E + H LH
Sbjct: 8 RFLAKQEFKRRKILMKKSKSSVVIQFYSRCYLQMEKRLKLRTELRQIVMVQSVVRRYLAKQEFKRRKSQMQMTKSS-----------------------VVIQSYVR---AKQKFKRRKIQME-----KNKSSVVIQSCVRGYLQKKKFKLMKDEIRKVVKVQSMV------RRFLAMKKKQKL---------------------VIGQGSI-------------HFKKQFIFKDDNNLAAICIQRNYRAWIYRKKFKKTIRCVIVIQSMWRGFRTRKSL---------------ICNTRLS----EVRARLVCANKEATENNKLCNRVSYVLYHLYNIKSLAVLIKIVNDLDASTRYSELCCDQMLENGDKKPVIVLLDLILRCNKSVPHIEVISGVLDTLINLVRYERTRL-YISGLRETYKTCLETLQRFEKSHVIIFAKVISFLYVLTFEKGGVEGVKKHFTKKIK-DYLMEYERKKHLLH 400
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000000998 (supercontig:LSalAtl2s:LSalAtl2s116:2039559:2041029:1 gene:EMLSAG00000000998 transcript:EMLSAT00000000998 description:"maker-LSalAtl2s116-augustus-gene-20.15") HSP 1 Score: 120.553 bits (301), Expect = 5.030e-30 Identity = 81/261 (31.03%), Postives = 141/261 (54.02%), Query Frame = 0
Query: 777 KIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSEND-RCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLL----ASSNRVKKILTLPLNAKKLLESHKHYHRLH----NKQMERGRRRNNYLPNS----FRPSPAQAKPKMPKLSLCPPWQIRED-----VIRHHKDPFLASEMVLNKLALKP 1019
++ EVR ++ N+ ATE+ KL NR + L LY + +A L+ I+ DLD +TR+S CCDQ++ D + V +LL+L+ RCN+S+PH+++IS +LD INL +YE +R+ + + +T +E L + V I+ K + L++L A +KK + + L+E + H LH + +G+RR + P S + A+AK K L + ++++D +++ K+ FL ++ L K+ P
Sbjct: 17 RLXEVRARLVCVNKEATENNKLCNRVSYVLCHLYNIKSLAVLIKIVNDLDASTRYSEFCCDQMLENGDKKPVIVLLDLILRCNKSVPHIEVISGVLDTLINLVRYERTRL-YISGLKETYKTCLETLQRFEKSHVIIFAKVISFLYILTFEKAGVEGIKKQFSKKVK-DYLMEYERKKHLLHKSVSKSKNVKGKRRIPHFPESHNCAISATIAEAKRKSDGLQIFLDKKMKKDRSQSRCLKYTKERFLWTQSRLCKVLEMP 275
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000003057 (supercontig:LSalAtl2s:LSalAtl2s172:803529:807762:-1 gene:EMLSAG00000003057 transcript:EMLSAT00000003057 description:"augustus_masked-LSalAtl2s172-processed-gene-7.0") HSP 1 Score: 73.559 bits (179), Expect = 2.222e-13 Identity = 122/502 (24.30%), Postives = 219/502 (43.63%), Query Frame = 0
Query: 248 LNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQ----------SYLRTQN---ACLAIQKYYRSHVARLAF-QAERKLESLA-------ATTIQSAWRRNQVRRERQRIIQTRNE-----------AALVIQSAWRQYQNRLCLERR-----IQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRK----SSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRG---KFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYR 701
L ++A KIQS +R + +R+ + E+ +L K++ +A+ +Q+ +G F+++K +A+ + +L K + +A +IQ+ +R +++R+ L +N A + IQ + AR QA+ L L+ A IQS +R Q R+ T NE AAL IQS +R ++ R ++ + + + +RIQ FR + R ++ L + +R +AI IQSH++G+ R+ I K ++I++Q +R + VR+ D +R +V +IQ R + KRL+E ++ A IQS ++ R +R+ A I+ E +AI IQ ++G R + L I++Q+ ++ ++ L +++A IQR +R R ++ T+SAI IQ +R KAR+ R
Sbjct: 15 LAEAAVKIQSVFRGFQTRKDITKEDVESLPDLND-------------------KELAEAAVKIQSVFRG------FQTRKSAAKEDEEPL----------PNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLNDENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRK-----YITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVGSAIRIQTVFRGYKARKKIRNNL---LLVR--------------SAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKE---IKKTTSAALMIQSCFK-RFKKRKLALIEKQKEEN----AAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQKAALQIQRVYRCFRTKESTEDI------TRSAILIQGAFRGFKARKKAR 445 HSP 2 Score: 70.0922 bits (170), Expect = 2.781e-12 Identity = 113/487 (23.20%), Postives = 219/487 (44.97%), Query Frame = 0
Query: 31 ERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRN----QSATLIQSHWKAHIQREQFC-------------ALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI---MADAQEELRQYSATLIQSQWRSHSERKAFLH----------LRHSTLRIQSEFRKWSAQKRFASMKWAATI-----IQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQA---QWRVWIQLKAYKQMRCSAIVL-QAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYL----RTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR 472
++++ + A +IQS ++ ++R+++ + +L + ++A IQS ++ R+ L A+V +QS FR K+R+R I+ L ++L+E +A IQ + + R+ + + D ++ SA IQS +R RK + L + L+IQS FR + +K+ K A + IQ +R Y+ + + + LL +SA KIQS+++ + R++ + E ++ + +A LIQ+ ++V LK Q R A++L Q+ ++G+ +S +R K + K+ +A IQ+ ++ ++ R+ L + +NA + IQK Y+ R + ++++E+L A IQS++R + R+E ++ +AAL IQ +R ++ + E ++ + IQ FR F R
Sbjct: 12 DKELAEAAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRV-------NNINDHSLPDLNDENLSE---------AAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRKYITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVGSAIRIQTVFRGYKARKKIRNNL---LLVRSAIKIQSHYKGYKVRKALI---NENKKRMR--AAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGY-----------------KSRKRLKEI---------KKTTSAALMIQSCFKRFKKRKLALIEKQKEENAAIQIQKVYKGFKTR---KDKKEMETLMFAVIKIQSSYRSYKRRKE----LEKDQKAALQIQRVYRCFRTKESTEDITRSAILIQGAFRGFKAR 441 HSP 3 Score: 69.3218 bits (168), Expect = 4.547e-12 Identity = 105/467 (22.48%), Postives = 202/467 (43.25%), Query Frame = 0
Query: 144 SATKIQGYWKMWRGRQAFLR----IMADAQEELRQYSATLIQSQWRSHSERKAFL-------------HLRHSTLRIQSEFRKWSAQKRF-------------ASMKWAATIIQRSWRHYRFVQHLHE------RIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQ---SYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCL---ERRIQACVRIQRGFRKFIQR--CCLQRCLSERIALRHEA--------QERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRF 558
+A KIQ ++ ++ R+ + + D ++ +A IQS +R RK+ L + ++IQS FR + ++KR ++ AA +IQ + + + L++ + + L +SA +IQS +R + +R+ Y+ EL + K++ +A+ +Q+ +G+ R++ + +K + V SA RIQT +R ++AR+ + L + + IQ +Y+ + R A E K AA IQS R +VR+ + Q R A ++IQS R Y++R L ++ A + IQ F++F +R +++ E A++ + +++ E+ A I IQS +R + +R+ +K+++ +Q+ R + + E S +IQ A+R F
Sbjct: 18 AAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLNDENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRK-YI-----TNNELPNLDD----------------KKLAMAALKIQSVFRGFRMRKKIDDKKTATLV------------------------GSAIRIQTVFRGYKARKKIRNNLLLVRSAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKEIKKTTSAALMIQSCFKRFKKRKLALIEKQKEENAAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQKAALQIQRVYRCFRTKESTEDITRSAILIQGAFRGF 438 HSP 4 Score: 60.8474 bits (146), Expect = 1.963e-9 Identity = 103/415 (24.82%), Postives = 174/415 (41.93%), Query Frame = 0
Query: 408 AATTIQSAWR----RNQVRRERQRIIQTRN-----EAALVIQSAWRQYQNRLCLERRIQ-------------ACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYI------------GLRKSSIMVQKQVRGWIVRR----------DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNY-----SAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACI-AQRRLVSMRESAR-------IIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRR---AVTVIQKHYRGYQVRTAFKSDCK 758
AA IQS +R R + +E + N EAA+ IQS +R +Q R + + A V+IQ FR F R + + ++ E+ S AAI+IQS + G+ R+ L +S+I +Q RG+ R+ D ++ + IQ +R F + K+++++ L A +IQ+++R AR++ ++N SAI IQSH++G R + + +R L ++CI A + +++E + +IQ R ++ + L E++K T +A+ IQS ++ K R+ LA E A IQ+ + + RK + AV IQ YR Y+ R + D K
Sbjct: 18 AAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLND-------ENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRKYITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVG-SAIRIQTVFRGYKARKK-----------IRNNLLLVRSAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKEIKK---TTSAALMIQSCFKRFKKRK-------LALIEKQKEENAAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQK 403
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000011962 (supercontig:LSalAtl2s:LSalAtl2s84:1272304:1281371:-1 gene:EMLSAG00000011962 transcript:EMLSAT00000011962 description:"maker-LSalAtl2s84-snap-gene-12.11") HSP 1 Score: 63.1586 bits (152), Expect = 3.868e-10 Identity = 49/145 (33.79%), Postives = 76/145 (52.41%), Query Frame = 0
Query: 512 WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREF-----------AQIQA-----SALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAK 640
+ ++ R L IM+QK V+GW+ R+ Y R ++ R++QR R F +R+ MR R Q A KIQ+ R + R+ F A+I+ + +E LK AILIQ H RG +QR K+L+ R I +Q++ +
Sbjct: 736 YMEKLRSEKLMACGIMIQKHVKGWLARKKYIRLLTATRLLQRLSRGFIARRRI---FHMR-RLQAAVKIQAFIRGXLRRKSFNRTKELTIGLQARIRGYNARKNHIEFLKEKKAILIQKHVRGFLQRSKYLKNRNQVILVQSIVR 876
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391789|sp|P62292.1|ASPM_MACMU (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 242.662 bits (618), Expect = 2.531e-64 Identity = 298/1227 (24.29%), Postives = 555/1227 (45.23%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY------RHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ +SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A IQ + R R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM+ Y + Q + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F +K + TIQ+A+R +VR ++ +I+ AA+V QSA W + + C + + +A V IQ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ + R+ IQRA++ + +++ + S I IQ +R ++ + + + H + A + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYRANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITIQSSYCTIR------RLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQK----SVRTIQAAFRGMKVR-QKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAVLLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3477 HSP 2 Score: 159.844 bits (403), Expect = 3.304e-38 Identity = 213/838 (25.42%), Postives = 391/838 (46.66%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++ Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMCKAIMVIQNYYHAYKAQVNQRKNFLRVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 151.754 bits (382), Expect = 9.756e-36 Identity = 221/909 (24.31%), Postives = 409/909 (44.99%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSER---------------------------KAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAW---RRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G Q++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ K + LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q + +QR+ + Q+RSA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA TIQS++ RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R + Y++ + + ++IQ + R ++ + L+H L + + F + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYRANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITIQSSYCTIRRLMVKKK----LQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKY-------RANKKKQKALQH------NELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIV 2773 HSP 4 Score: 139.043 bits (349), Expect = 8.581e-32 Identity = 194/731 (26.54%), Postives = 340/731 (46.51%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRG----WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS A++R AA +I K+W+ L Q+ L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW +K + +K A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ +MRL+ + +QS +RMR AR+ + ++ A+ ++NY ++ QR FLR+++ LQA + ++ + +A IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1261 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLC--RQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQLQKYKKMKK----AAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRK-----------------------------QMRLQRKAVISLQSYFRMRKARQYYLKM-CKAIMVIQNY----YHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN------KRVKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFR 1918 HSP 5 Score: 125.561 bits (314), Expect = 9.490e-28 Identity = 170/653 (26.03%), Postives = 303/653 (46.40%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWR---------------RHRLIRHLAELQKYKVMTQ------SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + A++R AA IIQ+ WR R + L + ++ N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR +++ K Y+ ++ S++++Q+ + W +RR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + + Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I +Q+H R Q Q+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R AR+ + I S ++ IQS++R V + +FL L+ T I+LQ++ K +++ + +R +A IQ+ +R R I+ A ++ Y V Q + I++QS +RM KAR++Y + A IQ + RK F+R+++A T +Q YRGY+VR K
Sbjct: 1260 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKW-KRRKMQSQVKATVILQRAFREW-------HLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKLQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGM-----------------------------QARKVYIHILTSVIK---------IQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMCK-------AIMVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIK 1822
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391788|sp|P62291.1|ASPM_MACFA (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 241.891 bits (616), Expect = 3.956e-64 Identity = 297/1227 (24.21%), Postives = 555/1227 (45.23%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY------RHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ +SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A IQ ++ R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM+ Y + Q + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F +K + TIQ+A+R +VR ++ +I+ AA+V QSA W + + C + + +A V IQ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ + R+ IQRA++ + +++ + S I IQ +R ++ + + + H + A + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQK----SVRTIQAAFRGMKVR-QKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAVLLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPXTPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3474 HSP 2 Score: 159.458 bits (402), Expect = 3.821e-38 Identity = 212/838 (25.30%), Postives = 391/838 (46.66%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R Q++ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++ Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHIRKHQQVQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQXKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 155.992 bits (393), Expect = 4.981e-37 Identity = 221/906 (24.39%), Postives = 407/906 (44.92%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSER---------------------------KAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + +CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G Q++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ K + LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q +QR+ + Q+RSA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA TIQS++RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R + Y++ + + ++IQ + R ++ + L+H L + + F + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQXKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHXXHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVXVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITIQSSYRRLMVKKK----LQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKY-------RANKKKQKALQH------NELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIV 2770 HSP 4 Score: 131.339 bits (329), Expect = 1.676e-29 Identity = 205/798 (25.69%), Postives = 363/798 (45.49%), Query Frame = 0
Query: 21 LVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQK---HLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRG----WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATK-------IQSLWRMRMA----RREFAQIQASA--------------LEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKA--CIAQRRLVSMRESARIIQ-----RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKK----FIRIRRAVTVIQKHYRGYQVR 750
L RL +L RK + A IQ+ W+ + KL +LKR+Q +R++ A+ ++QS A++R AA +I K+W+ L Q+ L + + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW +K + +K A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ R +V +Q +R MR Q+ K IQ+ + A R+ F +++ +A L + ++ +A+ IQS +RG +R K+ + ++ I++Q +A + R ++ A ++ R W+ + IR Q+A+ IQS +RM KA++ +R + A IQ++ + W +K +I +R AV ++Q ++G +R
Sbjct: 1256 LCARLLDL---RKEIRAARLIQTTWR----------KYKLKTDLKRHQ-------------ERDK------AARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNL--CRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQVQKYKKMKK----AAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFR-------------MRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRKQIRR---------EHQAALKIQSAFRMAKAQKQFRLF-------KTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLR 1964
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391784|sp|P62287.1|ASPM_COLGU (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 238.424 bits (607), Expect = 5.968e-63 Identity = 296/1228 (24.10%), Postives = 553/1228 (45.03%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRM-----------WMSR--RSYLRFQTEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++M R R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A +Q ++ R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM W ++ + R + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR ++ R F A +K + TIQ+A+R +VR++ + I + + AA+V QSA W + C + + +A V IQ+ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R ++ + + E G + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMQRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITVQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQAAYKGMKARQHLREK------HKAAIIIQSTYRMHRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNMQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTVVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYIRVKTERKIFLAVQK----SVRTIQAAFRGMKVRQKLKNISEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVTIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFRRMVTRKVETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGGFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYYSIEKIEHEGQECLSQRNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCVDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 162.925 bits (411), Expect = 3.410e-39 Identity = 215/838 (25.66%), Postives = 392/838 (46.78%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + +KF++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKFQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKIATQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQ---AAYRGYKIRQLIKQQSIAAVKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 151.369 bits (381), Expect = 1.361e-35 Identity = 222/907 (24.48%), Postives = 409/907 (45.09%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSERKAF---------------------------LHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQ-SLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G +++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ F LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q + +QR+ + Q+ SA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA T+QS++RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R Y++ + + ++IQ +R ++ + +E++ T +Q S M M ++ Q QA AI+IQ H + R +L LR T + +Q R+L +R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ ++++ RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATYIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQREKYLTILKAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMQRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITVQSSYRRLMVKKK----LQEMQRAAVLIQATFRMHRTYVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQAAYKGMKARQHLREKHKAAIIIQSTYRMHRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKE----TCVQASFQDMNMQKQIQEQHQA----------AIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTVVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYIRVKTERKIFLAVQKSVRTIQAAFRGMKVRQKLKNISEEKMAAIV 2770 HSP 4 Score: 142.51 bits (358), Expect = 6.607e-33 Identity = 201/737 (27.27%), Postives = 342/737 (46.40%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWR----GWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAIL-IQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS A++R AA +I K+W+ L Q+ L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW Q++ S A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ +MRL+ + +QS +RMR AR+ + LK Y AI+ IQ+++ QR KFLR+++ LQA + R+L+ + A + IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1261 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWK-QRKMQSQVKATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLC--RQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHIRKHQQLQKYKKMKK----AAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIATQKREEYMQMRESCIKLQAFVRGYLVRK-----------------------------QMRLQRKAVISLQSYFRMRKARQYY----------LKMYKAIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQAAYRG-YKIRQLIKQQSIAAVKIQSAFRGYN------KRVKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFR 1918 HSP 5 Score: 122.094 bits (305), Expect = 1.113e-26 Identity = 176/642 (27.41%), Postives = 307/642 (47.82%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW------ATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + A++R AA IIQ+ WR R + L + ++ N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR +++ K Y+ ++ S++++Q+ + W QR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + + Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I Q+H R Q Q+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS + R ++L LR + +Q +K Q+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM KAR++Y + A IQ + RKKF+R+++A T +Q YRGY++R K
Sbjct: 1260 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKQRK-MQSQVKATVILQRAFREW-------HLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKFQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYIHILTSVIKIQSYYRAYVSKKEFL--------SLKN-ATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIATQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKARQYYLKMYK-------AIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQAAYRGYKIRQLIK 1822 HSP 6 Score: 94.7449 bits (234), Expect = 3.236e-18 Identity = 146/585 (24.96%), Postives = 266/585 (45.47%), Query Frame = 0
Query: 1 MYLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAH----IQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSH----SERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAER--KLESLAATTIQSAWRRNQVRRERQRIIQTRNE--------------AALVIQSAWRQYQNRLCLERRIQACVRIQRGFR-KFIQRCCLQRCLS-ERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFA 559
++L +Q+SV IQ ++R + Q+L+ + E+ A QS +RS+ + E +++ T IQ +KA Q ++ + A+V +Q FR+ R+ T K AA I + + ++++ ++ R+A +Q Y++ W+ R+ FL L + +A ++Q+ +R+ +R+ +L +R S + IQ+ + + +++F +K + IQ WR YR ++L + ++A KIQ+++R W + + YL LKA K ++Q ++R F + + SA ++QR WR + H + H++A IQ +R ++ RQ +LR ++A L IQKY R AR A + ER +E +T I A R + R+RI++ R + AL IQ A++ Y +++ + + IQR FR + Q+ +Q+ S E+I HE QE +QR R ++ ++QK VR +++R+ E+ S + IQ WR ++
Sbjct: 2734 IFLAVQKSVRTIQAAFRGMKVRQKLKNISEEK---MAAIVNQSALCCYRSKTQ--------YEAVQSEGVT-IQEWYKASGLACSQEAEYHSQSRAAVTIQKAFRRM-VTRKVETQKCAALRIQFFLQMAVYRRRFVQQ------KRAAITLQHYFRTWQTRKQFL---------LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCK-------VKAACKIQAWYRCWRAHKEYLAI-------------------------LKAVK-------IIQGGFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIR---AREAGKRERIKYIEFKKSTVILQALVRGWL--VRKRILEQRTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQQKKFIQKYYSIEKI--EHEGQE-------------------CLSQRNR------AASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYS 3219
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391780|sp|P62283.1|ASPM_AOTVO (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 237.654 bits (605), Expect = 9.569e-63 Identity = 298/1223 (24.37%), Postives = 555/1223 (45.38%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHC----SATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRL-------------------CL--------ERRIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHKHY---HRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L LQ + IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ ++++++QS FR RRRF+++K+AA I + ++ + KH ++H L + ++A IQ ++ R+M + + +A LIQ+ +R H F +H+++ IQ +R + A Q+ + +W +A IIQ ++R + Q L E+ +++A IQS +RM+ Y + Q + + L+H + T +QA ++ + +K ++ ++I++Q K + ++ + + +QR +R+ V QS K +R MH +ATRIQ+ +RM +A Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + Q + AA+V QSA Y+++ CL + +A V IQ+ FR+ I R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q +++G+I +R +++ R+S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR L+++ + LQAL + + ++R++ R R++ +A R R + L+K S I IQ +R ++ + H E G + IQ++++ +++R+K + + Q +RGY R +DC KI+ +R + + N E+ KL RTALAL L + ++ +L +K L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +YR DKS I+TKT LL LL ++NR + + ++ +K H+++ +++ +++++ + F P + +L P W +R D + +P A +M+++ L +
Sbjct: 2304 FLRLQNAAIKIQSSYRRWMIRKKIREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKH---KLHQFLQLRKAAITIQSSYR---------RLMVKKKLQEMHRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSAVIIQAAYRGMKARQLLREK------HKAAIIIQSTYRMYRQCCLYQKLQWATKIIQEKYRANKKKHKALQHNELKKAETCLQASFQD-MNIKLIQEQDQTSIIIQKHCKAFKIKKHYLHLRAPVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHLAATRIQSFYRMHRATVDYQTKKTAVVLIQNYYRLYVRVKTERKSFLAVQK----SVRTIQAAFRGMKVRQKLKNVSQEK-MAAIVNQSALCCYRSKAQYEAVRSEGVIIQEWYKASCLACSQEAEYHSQSRAAVTIQKAFRRMITRKVETQKCAALRIQFFLQMAVYRRRFVQQKRAAVTLQHYFRMWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLRIRSSVIIIQARIKGFIQKRKFQKIRNSTIKIQAMWRRYRAKKSLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNLRASAIIIQRKWRAILSAKIAHEHFLMIQRHRAACLIQAHFRGYKGRQVFLRQKSAALNIQKYIRAREAGRRERIKYIELKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLKALRIQRAYKLYLALKKANKQINSVICIQRWFRARLQQKRFIQKCHSIKKIEHEGQERLSQQNRAASVIQKAVRHFLLRRKQEKFTSGIIKFQALWRGYSWRK--NNDCT------------------KIKAIRLSLQVVNREIREENKLYRRTALALHYLLTYKHLSAILEAVKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYREKPGNKVADKSGSIFTKTCCLLATLLKTTNRASDVRSRSKVVDRIYSLYKLTACKHKVNTERLLYKQKKDSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNLEEIINPLQAIQMLMDTLGI 3471 HSP 2 Score: 162.155 bits (409), Expect = 5.653e-39 Identity = 218/840 (25.95%), Postives = 392/840 (46.67%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
R+ +IQ +WR+Y L + L + L +K+N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK SV+LQS R A + AA I + W+ L +K +R ++ S+ IQ ++ W+ R+ L++ A Q R++ SA +IQS +R H + + ++++R + IQ FR + AQK + K + IQ+ +R Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+ +Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + L IQ+ YRS +LA Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + +R + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +IQ H R G QR +++ LR + + LQ++ K +R+L + A IIQ R H + +K+K+M ++ + IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + +
Sbjct: 1264 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLTKQRLRKKLN-AALVIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSVILQSRIRMIIAVTCYKRYLWAAVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQAMFRRWKRRKMQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLQKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYMKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRKIRAACVIQSYWRMRQDRVRFLNLKKIIIK---------LQAHVRKHQQLQKYKKMKKAAVTIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATVKLQSIVKMKQTRKQYLHLRATVLFIQRCYRS--KKLAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAAVKIQSAFRGYRKRVKYQSVLQSIIKIQRWYRAYKTLSDIRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAAMKIQSAFRMAKAQKQFRLFKTAAL---------VIQQHLRAWTAGRKQRMEYIELRHSVLMLQSMWKGKTLRRQLQRQHKCAVIIQSYDRMH------VQQKKWKIMKKAVLLIQKYYRAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKY 2059 HSP 3 Score: 141.354 bits (355), Expect = 1.644e-32 Identity = 202/813 (24.85%), Postives = 388/813 (47.72%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSL-VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKA----RRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR-------QAFLRI---------MADAQEELRQYSATLI--QSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQ---RSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGW-IQRRQ---FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRS-HVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKF----IQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVR----RDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKA----RRHY--------------------RHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
YL L+ +V IQR +R L Q+ EE + ++ + ++Q+F + + R+++ + K + L QS+++ R+ + + A +++Q+++ KA R+ FL +K+AA + ++G ++ + ++ + +A KIQ ++ +R R Q+ ++I ++D + + A +I QS +R RK + ++IQS FR AQK+F K AA +IQ R+W R +R+++ L S +QS W+ RR Q + +H A +IQ+ R+ +Q K +K M+ + +++Q + + I R Q + K + LQ ++R K + + K +++A IQ+++R ++ ++ Y + + + IQ++YR + ++ L+ A IQ+ +R +VRR IQ + AA I++ ++ +Q+R+ +A + IQ +R + +QR + L L +A R R+L AA LIQS++R + Q+ + L+K + VQ++ R R + Y + R SV IQ A+ + ++ + ++ H AT IQ +R M RR F ++ +A+ + Y A L H +FLRL+ I++Q+ + + ++++ M +A IQ +R HR+ H+ +Y+ + Q+++ IQ ++ ++A R+HY RHL + +SA + IQ + +VR++FI +++A IQ+ YR
Sbjct: 1694 YLHLRATVLFIQRCYRSKKLAAQKREEYM---QMRESCIKLQAFVRGYLVRKQMRLQRKAVISL---------QSYFRMRKARQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQ------SIAAVKIQSAFRGYRKRVKYQSVLQSIIKIQRWYRAYKTLSDIRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAAMKIQSAFRMAKAQKQFRLFKTAALVIQQHLRAWTAGR-----KQRMEYIELRHSVLMLQSMWKGKTLRR---------QLQRQHKCAVIIQSYDRMHVQQKKWKIMKKAVLLIQKYYRAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRI------KDCNKAAITIQSKYRAYKTKKKYAACRASAIIIQRWYRGIKITNHQYKEYLNLKK-TAIKIQAVYRGIRVRRH----IQHMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQRENYLKILKAVNVL--QANFRGVRVRRTLRKLQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAVKERNIQFQRYNKLRHSVIHIQ------AIFRGMKARRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWVQRKYRAHLCTKH------HLQFLRLQNAAIKIQSSYRRWMIRKKIREMHRAATFIQATFRMHRV--HM----RYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAIL----IQSRFRSLLVRRRFISLKKAAIFIQRKYRA 2439 HSP 4 Score: 137.117 bits (344), Expect = 2.754e-31 Identity = 208/873 (23.83%), Postives = 399/873 (45.70%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE---------LLRRLKLALELKRNQ---------SATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL----------AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEE--------QSEMRL--------RHQWATK-IQSLWRMRMARREFAQ----------IQAS------ALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ SV ++Q W+ +L ++L+ + ++CA IQS+ +MH +++ L+++ A + R Q + +QS ++ R++ A++ +QS +R K ++++ + +A +I +W++G H + +L+L ++A KIQ ++ R R+ F++ M + +Y + +IQ ++R++ + R+ +L + + +Q+ FR ++ ++ AAT+IQ ++R YR ++ F L + +Q +R R Q + +L H S IQA +R + K M +A ++Q + + + RR+F S K++A +QR +R + HHL++ R+ +A +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + + IQ FR FIQR C + L + + LR A + R + AA+LIQ+ +R + + +SI++Q+ R + + R +Y + S +IQ A+R + L E QS R+ + QWATK IQ +R + + Q +QAS L + ++ ++I+IQ H + + +L LR + +Q R+L ++R A I IQ +R ++ R + M +A IQS +RMH+A Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1940 YIELRHSVLMLQSMWKGKTLRRQLQ------RQHKCAVIIQSYDRMHVQQKKWKIMKKAVLLIQKYYRAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKYAACRASAIIIQRWYRGIKITNH-QYKEYLNL-KKTAIKIQAVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQRENYLKILKAVNVLQANFRGVRVRRTLRKLQIAATLIQSNYRRYR------QQTYFNKLKKITKTVQQRYRAVKERN----IQFQRYNKLRH-SVIHIQAIFRGMKARRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWVQRKYRAHLCTK---HHLQFLRLQNAAIKIQSSYRRWMIRKKIREMHRAATFIQATFRMHRVHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMKTRRHLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKHKLHQFLQLRKAAITIQSSYRRLMVKKKLQEMHRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSAVIIQAAYRGMKARQLLREKHKAAIIIQSTYRMYRQCCLYQKLQWATKIIQEKYRANKKKHKALQHNELKKAETCLQASFQDMNIKLIQEQDQTSIIIQKHCKAFKIKKHYLHLRAPVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHLAATRIQSFYRMHRATVDYQ-------TKKTAVVLIQNYYRLYVRVKTERKSFLAVQKSVRTIQAAFRGMKVRQKLKNVSQEKMAAIV 2766 HSP 5 Score: 80.1073 bits (196), Expect = 7.637e-14 Identity = 121/447 (27.07%), Postives = 193/447 (43.18%), Query Frame = 0
Query: 358 SATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRII-----QTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQR----QRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMR--------------MARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQA-------------LAKACIAQR---------RLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
+A IQT WR ++ + R Q A + + + L Q RK + AA IQ WRR +++ + + +N+AA +IQ WR+Y R + V +Q R I C +R L W AA+ IQ HWR + +R QRY L+ SS+++Q R W RR + + +QRA+R + L KR +E+ A IQS +RM + ++ F QA L + + S + IQ ++R G ++R +L+ R I+LQA + AC+ Q R +++++ +Q R+H+ +LQKYK M ++A+TIQ+ ++ + R SA + + R MQ RK +I I +V IQ +YR Y + F S
Sbjct: 1265 AARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLTKQRLRKKLN-AALVIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSVILQSRIRMIIAVTCYKRYL--------------W------AAVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQAMFRRW-KRRKMQLQVKATITLQRAFREWHLRKRAKEEKS-------AIVIQSWYRMHKQLQKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYMKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRKIRAACVIQSYWRMRQDRVRFLNLKKIIIKLQAHVRKHQ------QLQKYKKMKKAAVTIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQ---ARKMYIHILTSVIKIQSYYRAYVSKKEFLS 1673
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391793|sp|P62296.1|ASPM_SAIBB (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.572 bits (597), Expect = 9.439e-62 Identity = 302/1231 (24.53%), Postives = 548/1231 (44.52%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQT----------------EAQEELEHC----SATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-------------------NRLCL--------ERRIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATK-IQSLWRMRMARREFAQIQASAL----------------EEL----KNYSAILIQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKL-----LESHKH---YHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L LQ + IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R + ++ ++++++QS FR RRRF+++K+AA I + ++ + KH +H L + ++A IQ ++ R+M + + +A LIQ+ +R H F +H+++ IQ +R + A Q+ + +W +A IIQ ++R + Q L E+ ++A IQS +RM+ R Y +Q + + L+H + +QA ++ K ++ +++ +Q + ++Q+ + +QR +R+ V QS K +R MH +ATRIQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + Q + AA+V SA Y+ CL + +A V IQ+ FR+ I R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R +++ ++S IQ WRR+ K L + W A K IQ + ++ R F ++ASA+ E ++ +A LIQ+H+RG R FLR L+++ + LQAL + + ++R++ R R++ +A R R + L+ SAI IQ +R ++ + + H E G + IQ++++ +++RKK + + Q +RGY R +DC KI+ +R + + N E+ KL R ALAL L + ++ +L +K L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +YR DKS I+TKT LL LL ++NR + + ++ L ++KH RLH KQ + ++P +P + + L P W +R D + +P A +MV++ L +
Sbjct: 2299 FLRLQNAAIKIQSSYRRWVVRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMETRRRLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKH---NLHQFLQLRKAAVTIQSSYR---------RLMVKKKLQEMHRAAVLIQATFRMHKTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSALIIQAAYRGMKARQLLREK------RKAAIIIQSTYRMY---RQYCLYQNLQWATKIIQEKYRANKKKHKALQHNELKKAEACVQASFQDMNIKKLIQEQHQTSLTIQKHCNAFKIKKQYLHLRAPVVSIQRRYRKLTAVHTQAVICIQSYYRGFKVRRDIQNMHLAATRIQSLYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERNSFLAVQK----SVRTIQAAFRSMKVRQKLKNLSQEK-MAAIVSPSAVYCYRIEAQSEAVGSEGVIIQEWYKTSCLAHSQEAEYHSQSRAAVTIQKAFRRMITRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAVTLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARTKGFIQKRKFQKIKNSTIKIQAVWRRYRDKKSLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGSFYXKLERTRFLNMRASAIIIQRKWRAILSAKIAHEHFLMIQRHQAACLIQAHFRGYKGRQVFLRQKSAALNIQKYIRAREAGRRERIKYIELKKSTVTLQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLKALRIQRAYKLYLALKNANKQVNSAICIQRWFRARLQQKRFIQICHSIKKIEHEGQERLSQQNRAASVIQKAVRHFLLRKKQEKFTSGIIKFQALWRGYSWRK--NNDC------------------TKIKAIRLSLQVVNREIREENKLYRRAALALHYLLTYKHLSAILEAVKHLEVVTRLSPFCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYREKPGNKVADKSGSIFTKTCCLLATLLKTTNRASDVRSRSKVVDRIYSLYKLTAYKHKVNTERLHYKQKKDSSTSIPFIPE----TPVRTRIVS---RLKPDWVLRRDNLEEITNPLQAIQMVMDTLGI 3467 HSP 2 Score: 163.31 bits (412), Expect = 2.377e-39 Identity = 217/839 (25.86%), Postives = 392/839 (46.72%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
R+ +IQ +WR+Y L L+ +I IN A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S+VLQS R A + A I + W+ L +K +R + S+ IQ ++ W+ R+ L++ A Q R++ SA +IQS +R H + + ++++R + IQ FR + AQK + K + IQ+ +R Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ RM Q R+ YL + L IQ+ Y H +LA Q + + + I+ A+ R + R++ R+ + +A + +QS +R ++R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+++R +Y + +S I +Q+ R + +R + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +IQ H R G QR +++ LR + + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R +H +L A A T+Q + + VRK+ +A IQ YR Y+ + +
Sbjct: 1259 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQR--YEKLKSSSLIIQAMFRRWKQRKMQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLRKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRQIRAACVIQSYWRMRQDRVRFLNLKKIIIK---------LQAHVRKHQQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVRMKQTRKQYLHLRATALFIQQCY--HSKKLAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKSRQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSVAAVKIQSAFRGYSKRVKYQSVLQSIIKIQRWYRAYKTLHGIRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAAMKIQSAFRMAKAQKQFRLFKTAAL---------VIQQHLRAWTAGRKQRMEYIELRHSVLMLQSMWKGKALRRQLQRQHKCAVIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGRE-QHCLYLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKY 2054 HSP 3 Score: 132.109 bits (331), Expect = 1.114e-29 Identity = 212/893 (23.74%), Postives = 398/893 (44.57%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAH-IQREQFCA-LKT-------------------------ASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL---------------------------------AAILIQSHWRGW----TQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQ---RAWRRFALIKRLEEQSEMRLRHQWATK-IQSLWRMRMARREFAQ----------IQAS-------ALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ SV ++Q W+ +L ++L+ + ++CA IQS+++MH +Q+ + +K ++A LIQ +++A+ I REQ C LKT A++ +QS +R K ++++ + +A +I +W++ H + +L+L ++A KIQ ++ R R+ F++ M + +Y + +IQ ++R++ + R+ +L + +Q+ FR ++ ++ AAT+IQ ++R YR ++ F L + +Q +R R Q + +L H S IQA +R + K M +A ++Q + + + RR+F S K++A +QR +R + HHL++ R+ +A +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + + IQ FR FIQR C + L + + LR A + R + A+ILIQ H+R + QR+ Y S++++Q RG R+ R + +IQ R +R++ L + L QWATK IQ +R + + Q +QAS L + ++ +++ IQ H + ++L LR + +Q R+L ++ A I IQ +R ++ R + M +A IQSL+RMH+A+ Y+ + + A IQ +++V R F+ ++++V IQ +R +VR K+ + K A++
Sbjct: 1935 YIELRHSVLMLQSMWKGKALRRQLQ------RQHKCAVIIQSYYRMH-VQQKKWKIMK--------KAALLIQKYYRAYSIGREQHCLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKYAAYRASAIIIQRWYRSIKITNH-QYKEYLNL-KKTAIKIQAVYRGIRVRRHIQCMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQREDYLKFLKAVNVLQANFRGVRVRRTLRKLQIAATVIQSNYRRYR------QQTYFNKLKKITKTVQQRYRAVKERN----IQFQRYNKLRH-SVIHIQAIFRGMKVRRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWIQRKYRAHLCTK---HHLQFLRLQNAAIKIQSSYRRWVVRKKMREMHRAATFIQATFRMHRVHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMETRRRLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKHNLHQFLQLRKAAVTIQSSYRRLMVKKKLQEMHRAAVLIQATFRMHKTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSALIIQAAYRGMKARQLLREKRKAAIIIQSTYRMYRQYCLYQNL----------QWATKIIQEKYRANKKKHKALQHNELKKAEACVQASFQDMNIKKLIQEQHQTSLTIQKHCNAFKIKKQYLHLRAPVVSIQR------RYRKLTAVHTQAVICIQSYYRGFKVRRDIQN------MHLAATRIQSLYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERNSFLAVQKSVRTIQAAFRSMKVRQKLKNLSQEKMAAIV 2762 HSP 4 Score: 120.553 bits (301), Expect = 3.810e-26 Identity = 197/736 (26.77%), Postives = 349/736 (47.42%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSA-ILIQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS ++R AA +I K+W+ L QK L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR+ RK + L+ S+L IQ+ FR+W +K +K A +QR++R + HL +R + +SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H Q RK + + AA IQ+ ++ R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + E ++L++ A I +QS R R++Y+ LR +++ +Q+ + R +Y + R S +Q A+ R L+++ +MRL+ + +QS +RMR +R+ + LK Y A I+IQ+++ QR FL++++ LQA + R+L+ + A + IQ A+R + ++ KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1252 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQRYEKLKSSSLIIQAMFRRWKQRKMQLQVK-ATITLQRAFREW----HLRKRAK---EEKSAIVIQSWYRMHKQLRKYVYVRS---------CVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLH--RQIRAACVIQSYWRMRQDRVRFLNLKKIIIKLQAHVRKH------QQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSK-------KEFLSLKN-------------ATIKLQSIVRMKQTRKQYLHLRATALFIQQCYHSKKLAAQKREEYMQMRESCIKLQ-AFVRGYLVRK-----QMRLQRKAVISLQSYFRMRKSRQYY----------LKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRG-YKVRQLIKQQSVAAVKIQSAFRGY------SKRVKYQSVLQSIIKIQRWYRAYKTLHGIR--THFLKT-KAAVISLQSAYRGWKVRKQIRREHQAAMKIQSAFRMAKAQKQFR 1909 HSP 5 Score: 118.242 bits (295), Expect = 1.754e-25 Identity = 173/658 (26.29%), Postives = 298/658 (45.29%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWR-------HYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR------RFKFVQSLAHHLKWKRMHQSATR----------IQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW------ATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + ++R AA IIQ+ WR + ER+Q N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR ++ K Y++++ S++++QA + W QR+ + Q ++ LQR++R R K +S W RMH+ + IQ ++R +QA++ Y R + + L IQKYYR+++ + + AA +Q+A+RR + ++I AA VIQS WR Q+R+ +F+ L++ + I +Q+H R Q ++Y ++K+++++Q + +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS R R ++L LR T + +Q +K AQ+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM K+R++Y + A IQ + RK F+++++A T +Q YRGY+VR K
Sbjct: 1251 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQ----NKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQRYEKLKSSSLIIQAMFRRWKQRK-MQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLRKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRQI-----RAACVIQSYWRMRQDRV-----------------RFLN---LKKII-----------------------IKLQAHVRKHQQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYIHILTSVIKIQSYYRAYVSKKEFL--------SLKN-ATIKLQSIVRMKQTRKQYLHLRATALFIQQCYHSKKLAAQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKSRQYYLKMYK-------AVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIK 1813
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391787|sp|P62290.1|ASPM_HYLLA (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.187 bits (596), Expect = 1.360e-61 Identity = 296/1222 (24.22%), Postives = 541/1222 (44.27%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQK----RFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-RKFIQRCCLQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ ++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A K + +A +IQ +++ + Q L E+ +++A IQS +RM+ Y + Q + Q+ +H T +QA ++ K + +AI++Q K + R+ + + + +QR R+ V QS K +R MHQ+AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + + R AA+V QSA W + C + + +A V IQ+ F R ++ Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R +++ ++S IQ WRR K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R++ A R R + ++ S I IQ +R ++ + H E G + IQ+++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLXSMHFSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFRTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKQQKAFQHNELKKETCVQASFQDMNIKKQIXEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRHRKLAAVRTQAVICIQSYYRGFKVRRDIQNMHQAATLIQSFYRMHKAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEER-MAAVVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKCAALRIQFFFQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQQIKNSTIKIQAMWRRXRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRIIEQRAKIRLLHFTAAAYYHLNALRIQRXYKLYLAVKNANKQINSVICIQRWFRARLQQKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVXHFLLRKKQEKFTNGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 157.532 bits (397), Expect = 1.638e-37 Identity = 208/841 (24.73%), Postives = 383/841 (45.54%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKR-----------------------NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHER-------IQFRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ ++ ++ A IQS ++Q L +R+ AL +++ N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y +L +R FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A IQS +RM A+ +F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K M ++A+ IQ +R + R HL ++A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKR---HQETDKAARIIQSAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATIILQRAFREWHLRKQAKEENSAIVIQSWYRMHKELRKYIYIRSCXVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIRLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHVRKHQQLQKYKKMKKAAVIIQTHFRAXIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRXQYLHLRAAALFIQQCYRS--KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSMLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALTIQSAFRMAKAQXQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKTMKKAALLIQKYYRAYSIGREQ---NHLYLKTKVAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 139.043 bits (349), Expect = 7.747e-32 Identity = 198/798 (24.81%), Postives = 374/798 (46.87%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKM------WRGR-------QAFLRIMADAQEELRQY-----SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKW--KRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQR----RLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMW----VVRKKFIRIRRAVTVIQKHYRGYQVR 750
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ + QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L +R H + A IQ Y++M W+ Q + R + +E+ Y + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H++ + L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +QR ++ + ++ ++LQ S+R + ++W ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA VIQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q Y+ +R++ +L+ Q +R RH A +Q+ +R RR + ++SA LIQS +R + R +F+ L++ I +Q +A I + + + +R++A IQ ++RR + + L E+Q+ +A+ IQ+ +RMH+ +R H A IQ+ + + + R+ +IR + VIQ Y+G + R
Sbjct: 1844 YQSMLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSAYRGWKVRKQIRRE---------HQAALTIQSAFRMAKAQXQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQL-QRQH-----KCAIIIQSYYRMHVQQKKWKTMKKAALLIQKYYRAYSIGREQNHLYLKTKVAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKK--YLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQREKYLTILKAVKILQASFRGVR--------VRWTLRKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATVIQRRFRT----LMMRRRFLSLKKTAIWIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQALKQASVVIQQQ---------YQANRAA---------------KLQRQHYLRQRHS-AVILQAAFRGMKTRRHLXSM---------HFSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQR------AAVLIQATFRMHRTYITFRTWKH-------ASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKAR 2547
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391790|sp|P62293.1|ASPM_PANTR (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.187 bits (596), Expect = 1.373e-61 Identity = 294/1228 (23.94%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQK----RFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A K + +A +IQ +++ + Q L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F + + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRSIP M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAVVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAECHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 169.474 bits (428), Expect = 3.278e-41 Identity = 209/840 (24.88%), Postives = 392/840 (46.67%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA------------QEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAF----QAERKLESL---------------AATTIQSAWRRNQV-RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR---------------------------------KFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R+ ++ A ++ Q SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++ ER + +A ++Q+ +R + Y + + +A +IQ+ WR+ + ++ + I LQA V+ QR++++ K++A ++Q +R + F + ++++ + +Q+ +R QAR+ Y+ + + IQ YYR++V++ F A KL+S+ AA IQ +R ++ ++R+ +Q R E+ + +Q+ R Y R + R +A + +Q FR F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEQNSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAY--LKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLYRQIR----------AACVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVL--ASYQKIRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMR-ESCIKLQAFVRGYLVRKQMRLRRKAVISLQSYFRMRKAQQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 142.124 bits (357), Expect = 8.532e-33 Identity = 210/852 (24.65%), Postives = 401/852 (47.07%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFI 787
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ ++QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +QR ++ + ++ +VLQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR+ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+L++ + Q SA+ IQ+ ++ KAR+ L A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I+E Q I
Sbjct: 1844 YQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSAYRGWKVRKQIRRE---------HQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAILIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQ-------LLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQEQHQAAII 2630
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391791|sp|P62294.1|ASPM_PONPY (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 233.032 bits (593), Expect = 3.194e-61 Identity = 296/1228 (24.10%), Postives = 548/1228 (44.63%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-RKFIQRCCLQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++M R R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL +SA IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A Q+ +W +A +IQ +++ + Q L E+ +++A IQS +RM+ Y + Q + Q+ +H T +QA ++ K + +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F R ++ Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R R+ + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2302 FLRVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQAIFRMRRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKSAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQDQHQAAIIIQKNCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLAVQK----SVRTIQPAFRGMKVRQKLKNLSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAIWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRATCLIQAHYRGYKGRQVFLRQKSAALVIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQRKRFIQKYHSIKKIEHEGQECLSQQNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PNWVLRRDNMEEITNPLQAIQMVMDTLGI 3469 HSP 2 Score: 159.844 bits (403), Expect = 2.735e-38 Identity = 214/844 (25.36%), Postives = 385/844 (45.62%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQV-RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR---------------------------------KFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q +Q +W+ ++++LL K LE +N++A+LIQ +W+ + R +F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L S +IQ+ +R + +++ +L +NA + +Q + R + R AA IQ +R ++ ++R+ +Q R E+ + +Q+ R Y+ R + + +A + +Q FR F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q +R + + K ++R HQ A KIQS +RM AR++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1262 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQSAVINFLAKQRLRKRVNAALVVQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKQAKEENSAIVIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAAGVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHVRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHIL------TSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKVKQTRKQYLHLRA----AALFIQQCYRSKKIAAQKREEYMQMR-ESCIKLQAFVRGYRVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRIKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSTYRGWKVRK------QIRREHQAALKIQSAFRMAKARKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2059 HSP 3 Score: 142.51 bits (358), Expect = 6.549e-33 Identity = 209/854 (24.47%), Postives = 403/854 (47.19%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFI-QRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANEN 791
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ R+QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +Q ++ + ++ ++LQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + + LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR++ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+LQ+ + Q SA+ IQ+ ++ KAR+ L A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I++ Q I +N
Sbjct: 1838 YQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSTYRGWKVRKQIRRE---------HQAALKIQSAFRMAKARKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQHEKYLTILKAVKILQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAIWIQRKYRAHLYTKHHLQFLRVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQAIFRMRRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKSAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQ-------LLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQDQHQAAIIIQKN 2628 HSP 4 Score: 137.117 bits (344), Expect = 3.465e-31 Identity = 207/768 (26.95%), Postives = 356/768 (46.35%), Query Frame = 0
Query: 21 LVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQK---HLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAIL-IQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L RL +L RK + A IQ+ W+ + KL +LKR+Q +RE+ A+ ++QS A++R AA V+ K+W+ L Q+ L + + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ STL IQS FRKW +K + +K A I+QR++R + H R Q + N SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + E ++L++ A I +QS + R++Y+ LR +++ +Q+ R + R +Y + R S +Q A ++ + +MRL+ + +QS +RMR AR+ + LK Y AI+ IQ+++ QR FL++++ LQA + ++ + +A IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + R F+
Sbjct: 1250 LCARLLDL---RKEIRAARLIQTTWR----------KYKLKTDLKRHQ-------------EREK------AARIIQSAVINFLAKQRLRKRVNAALVVQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW------HLRKQAKEEN-SAIVIQSWYRMHKELRKYIYIRS---------CVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNL--CRQIRAAGVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQLQKYKKMKK----AAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSK-------KEFLSLKN-------------ATIKLQSIVKVKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQ------AFVRGYRVRKQMRLQRKAVISLQSYFRMRKARQYY----------LKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN------KRIKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVISLQSTYRGWKVRKQIRREHQAALKIQSAFRMAKARKQFR 1912
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391786|sp|P62289.1|ASPM_GORGO (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 233.032 bits (593), Expect = 3.224e-61 Identity = 294/1228 (23.94%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-----RK-------------FIQRCCLQR--CLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASAL----------------EEL----KNYSAILIQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A Q+ +W +A +IQ +++ + L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MHQ+AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F RK F+Q +R +R A+ + R W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ E ++ +A LIQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + ++H + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+ + +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2307 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARHLLREK------HKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHQAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMEVRQKLKNVSEEK-VAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKYAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNALRIQRAYKLYLAMKHANK------QVNSVICIQRWFRARLQEKRFIQKYHSVKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAHSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3474 HSP 2 Score: 160.614 bits (405), Expect = 1.694e-38 Identity = 208/839 (24.79%), Postives = 390/839 (46.48%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAF----QAERKLESL---------------AATTIQSAWRRNQV-RRERQRIIQTRN----------------------EAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R +F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++ ER + +A ++Q+ +R + L Q A A +IQ+ WR+ + ++ + I LQA V+ QR++++ K++A ++Q +R + F + + +++ + +Q+ +R QAR+ Y+ + + IQ YYR+HV++ F A KL+S+ AA IQ +R ++ ++R+ +Q R +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + ++++++ +Q A+R + + K ++R HQ KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ + +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1267 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLVIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKHAKEENSAIIIQSWYRMHKELQKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAY--LKGKIERTNYLQKRAAAIQLQAAFRRLKAHN--LCRQIRA--------ACVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVL--ASYQKTRSAVIVLQSAYRGMQARKMYVHILTSVIKIQSYYRAHVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAALISLQSAYRGWKVRK------QIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKA------WTAGRKQRMEYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2064 HSP 3 Score: 141.739 bits (356), Expect = 1.231e-32 Identity = 201/805 (24.97%), Postives = 380/805 (47.20%), Query Frame = 0
Query: 50 SRQELLRRLKLALELKRNQSATL-IQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFI 787
S Q R K+ +++R A L IQS ++ ++QF KTA++V+Q +F+ A R+ ++ ++ A ++ W+G ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G QR ++ + ++ ++LQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR+ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+LQ+ + Q SA+ IQ+ ++ KAR HL A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I+E Q I
Sbjct: 1879 SLQSAYRGWKVRKQIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKAWTAGRKQRMEYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAVFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKTQREKYLTILKAVKILQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRKQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAILIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKAR-------HLLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQEQHQAAII 2629 HSP 4 Score: 125.176 bits (313), Expect = 1.527e-27 Identity = 178/642 (27.73%), Postives = 308/642 (47.98%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWA------TKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER+ + IQ + A++R AA +IQ+ WR R + L + ++ N++A+ IQ YWR + +RR +L+ + + Q + A IQ WR +++ K Y+ ++ S +V+Q+ + W QR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + Q Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I +Q+H R QRQ+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS + R ++L LR + +Q +K AQ+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM KAR++Y + A IQ + RK F+++++A T +Q YRGY+VR K
Sbjct: 1259 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQEREKAARI------IQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLVIQSMFRKWKQRK-MQSQVKATVILQRAFREW-------HLRKHAKEENSAIIIQSWYRMHKELQKYIYIRSCVVIIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYVHILTSVIKIQSYYRAHVSKKEFL--------SLKN-ATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKARQYYLKMYK-------AIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIK 1821
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|215273935|sp|Q8IZT6.2|ASPM_HUMAN (RecName: Full=Abnormal spindle-like microcephaly-associated protein; AltName: Full=Abnormal spindle protein homolog; Short=Asp homolog) HSP 1 Score: 231.876 bits (590), Expect = 6.280e-61 Identity = 295/1228 (24.02%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQS ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L + +HL ++A IQ ++ R+M + + Q +A LIQ+ +R + F +H+++ IQ +R + A Q+ +W +A +IQ +++ + Q L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F + + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R + R R+ IQRA++ + +++ + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRSIP M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 160.999 bits (406), Expect = 1.310e-38 Identity = 213/836 (25.48%), Postives = 391/836 (46.77%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSR-------RSYLRFQTEAQEELE-------HCSATLIQAQWRVWI----QLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R ++ ++FQ ++ + +A +IQ +R +I L +Y++ R + IVLQ+ +G R+ + S +Q +R + ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G Q +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAY------VSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS--KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 147.902 bits (372), Expect = 1.703e-34 Identity = 209/872 (23.97%), Postives = 407/872 (46.67%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL----------AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEE--------QSEMRL--------RHQWATK-IQSLWRMRMARREFAQ---------IQASALE-------ELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V ++Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G H ++ +L+L ++A KIQ ++ R R+ F++ M + Y +A +IQ + R++ + R+ +L + + +Q+ FR ++ M+ AAT+IQ ++R YR ++ F L + +Q R W + ++FQ +L H S IQA +R + K M +A ++Q + + + RR+F S K++A ++QR +R + HHL++ ++ + +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + IQ FR F+QR C + L + + LR A + R + AA+LIQ+ +R + + + +SI++Q+ R + + R +Y R S VIQ A++ + L E QS R+ + QWATK IQ +R +++ Q +QA + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I +++ R +R ++Q M ++A IQS +RMH+A+ Y + + A IQ +++V RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1944 YIELRHAVLVLQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKE-YLNL-KKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYR------QQTYFNKLKKITKTVQQ--RYWAMKERNIQFQR--YNKLRH-SVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTK---HHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVR--KDIQN---MHRAATLIQSFYRMHRAKVDYE-------TKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIV 2770
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|803295328|ref|XP_012007292.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein homolog isoform X2 [Ovis aries musimon]) HSP 1 Score: 250.366 bits (638), Expect = 2.352e-64 Identity = 290/1069 (27.13%), Postives = 521/1069 (48.74%), Query Frame = 0
Query: 33 KINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLI--QSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKG-------------------CLFQKHLNERIHLSLMNRSAT--KIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHL----------------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAF-QAERKLE-SLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY----------RHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLW-LLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
++ + ++QS +M ++R++ L +A + + + A+ I Q+ + ++ R+Q + A+V+LQS+FR K R +L + +AA VI ++++ CL + ++ L +SA KIQ ++ +R R + ++ A + R Y + S RSH F R + + +QS +R W +K+ AA IQ ++R R + +FRLL +A+ IQ + R +R + LR +TE L + TL A + + KQ RC AI++QA + +QR+++E K++AR++Q +R ++ + HHL K K MHQ+AT IQ+++R +QAR+ Y + A + IQ++YR+ A+LA Q E L AA IQ+ +R + RR+ +R+ + AA +I++A++ Q+R ++ A + IQ +R RH+A+ + E + AA IQ+ +R R+ Y+ + ++ ++Q+ RR + R+S +IQR WR + EQS M RHQ A IQ+ +R AR+ F Q +++AL + I++ G QR K++ L+++ + LQAL + + ++R+ R R+ IQRA+RRH +++ Q SAI IQ +R R+ + R A+ A + IQR+++ +++RKK + + + IQ +RGY R K+D + K + +RQ++ N E+ KL +RT AL L + ++ +L LK L+ TR S+ CC++ M+++ ++ + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +Y++KS D I+TKT LL LL ++ R I + ++ +K H H+++ +++ +++N+ + SF P + +L P W +R D + P A +MV++ L+L
Sbjct: 1681 RLKKATVKLQSIVRMKQARKQYLHLRAIAQQREEHLRASCIKLQAFLRGYLVRKQVRLQRKAAVLLQSYFRMRKMRLEYLKVCQAAVVIQRYYRAHRAGAQQRKHFLQVRRAVTCLQAAYRGYKVRRQLQQQSAAALKIQAAFRGYRQRTKYQSMLQSALKIQRWYRTRKMVSAVRSH-----FFKTRTAAISLQSAYRGWKVRKQMRKEHEAAVKIQSAFRTAR------AQKEFRLLKTAASVIQQHLR---ARATGLRQRTEYMA-LRRAAVTLQSAWRGRAARRRIQKQQRC-AIIIQACYRRHVQRKRWEIMKKAARLIQMHYRAYRTGRK-QHHLFLKTKGAAIILQSAFRGVRARKKVKEMHQAATTIQSRYRAYQARKKYASYRAAAVIIQRWYRA--AKLAGCQREEYLAVKKAALKIQAVYRGVRERRQTRRM----HMAATLIKAAFKMQQSRRRYQQMRTAAIVIQAVWR------------------RHKAR-KYLREVK--AACRIQAWYRCRKARKEYLAVLRAVRIIQRCFCTQQQRRRFLNVRASAVIIQRRWRAVLSGRTTHEQSLMTKRHQAACLIQANFRGYKARQVFLQQKSAALTIQR-----FIRARKAGKHQRMKYVELKKSTVVLQALVRGWLVRKRISEQRAKIRLLHFAAAAFYHLSALRIQRAYRRHMALKNANNKQ-----LNSAICIQRWFRARSQRKRFLQKYSIVNIQREAREQASQHSRAASVIQRAVRRFLLRKKQENLNKRIAKIQALWRGYSWRK--KND------------------TSKTKAIRQRLQCVNREIREENKLYHRTVFALHHLLTYKYLSTVLEALKHLEAVTRLSSVCCEK-MAQSGAISKVFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAIYD-VENCVDTLLELLQMYQEKSGDKVADKSRSIFTKTCCLLAVLLKTTTRASDIQSRSKVVDRIYSLYKLTAHKHKVNTERILCKQKKNSSVSLSFFPETPVRTRMVSRLK--PDWVLRRDNVEEIMTPLKAIQMVMDTLSL 2670 HSP 2 Score: 164.851 bits (416), Expect = 2.498e-37 Identity = 225/834 (26.98%), Postives = 394/834 (47.24%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWR--GRQAFL-------------RIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQF--------------------RLLNQ--SATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQ-----AERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK----------FIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQK--QVRGWI--VRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L+ +I IN A IQ +W+ ++++LL K LE ++SA++IQ +W+ + R+QF LK S++LQS R A + A I + W+ + K +R L+ S IQ ++ WR RQ+ + R+ AQEE +A +IQS +R H E + ++HLR + IQ+ FR + AQK + + + +Q+ +R Y V+ ER + L Q +A +QS WRM R +L + + +QA R QL+ Y++M+ +A+V+Q + +I ++ ++ + + VLQ + RR + + H L + +IQ+ +R + +R+ +LR + A + +Q R AR + A+++ E L A+ I+ A+ R + R++ R+ + +AA+++QS +R + RL + QA V IQR +R F+Q ++R ++ A + R + +S AA+ IQ+ +RG+ QR +Y + +S++ +Q+ + R + VR + ++R++ +Q A+R + + K +MR H+ A KIQS +R A++EF L +A +IQ H R G QR +++ LRR + LQ+ + A+RR+ + A IIQ +RRH + +++++M ++A IQ +R A R R HL + A +Q + + RKK + +A T IQ YR YQ R + S
Sbjct: 1272 RAARLIQTTWRQYKLKKDLKHHQERDKAARIIQSAIINFLTKQRFKKKVSAALVIQKYWRRALAKRKLLMLKKEKLERVHSKSASIIQRYWRRYSTRKQFLKLKYYSIILQSKIRMIIAVASYKRYHWATVTIQRHWRAHVRSKQ--DRQRYELLRSSTLVIQSAFRRWRRHKRQSQINAAITLQRAFREWRVQKRAQEE---RAAVVIQSWYRMHRESQKYIHLRSCVIIIQARFRCFQAQKLYTRTRESILTLQKHYRAY--VKGKVERTGYLQKRAAAIRLQAAFRGRRARNLCKQIRAACVLQSCWRMRQDRLRFLNLKK---------NIIRLQAHIRRRQQLQTYQKMKKAALVIQIHFRAYISAKEVLASYQKTRSAVIVLQSACRRMQARKKFLHIL------TAVVKIQSYYRAYASRRKFLRLKKATVKLQSIVRMKQARKQYLHLRAIAQQREEHLRASCIKLQAFLRGYLVRKQVRL---QRKAAVLLQSYFRMRKMRLEYLKVCQAAVVIQRYYRAHRAGAQQRKHFLQ---VRRAVTCLQAAYRGYKVRRQLQQQSAAALKIQAAFRGYRQRTKYQSMLQSALKIQRWYRTRKMVSAVRSHFFKTRTAAISLQSAYRGWKVRK------QMRKEHEAAVKIQSAFRTARAQKEF---------RLLKTAASVIQQHLRARATGLRQRTEYMALRRAAVTLQSAWRGRAARRRIQKQQRCAIIIQACYRRH------VQRKRWEIMKKAARLIQMHYR---AYRTGRKQHHLFLKTKGAAIILQSAFRGVRARKKVKEMHQAATTIQSRYRAYQARKKYAS 2053 HSP 3 Score: 94.7449 bits (234), Expect = 9.474e-16 Identity = 124/461 (26.90%), Postives = 222/461 (48.16%), Query Frame = 0
Query: 326 QKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYR-----SHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQR------IIQTRNE-------------AALVIQSAWRQY----QNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHE-----AQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
+ R+AR++Q +WR++K + L HH + ++A IQ+ + +Q + + +A L IQKY+R + L + ++ S +A+ IQ WRR R++ + I+Q++ A + IQ WR + Q+R E + + IQ FR++ +R Q ++ I L+ Q+RA E AA++IQS +R + Q+YI LR I++Q + R + ++ Y R+R S+ +Q+ +R A +K E++ + A ++Q+ +R R AR QI+A A ++QS WR R +FL L++ IRLQA + + M+++A +IQ +R + + + L Y+ + I +QS R +AR+ + H+ A IQ + + R+KF+R+++A +Q R Q R +
Sbjct: 1270 ETRAARLIQTTWRQYKLKKDLKHH---QERDKAARIIQSAIINFLTKQRFKKKVSAALVIQKYWRRALAKRKLLMLKKEKLERVHSKSASIIQRYWRRYSTRKQFLKLKYYSIILQSKIRMIIAVASYKRYHWATVTIQRHWRAHVRSKQDRQRYELLRSSTLVIQSAFRRW-RRHKRQSQINAAITLQRAFREWRVQKRAQEER---AAVVIQSWYRMHRESQKYIHLRSCVIIIQARFRCFQAQKLYTRTRESILTLQKHYR--AYVKGKVERTGYLQKRAAAIRLQAAFRGRRARNLCKQIRA----------ACVLQSCWRMRQDRLRFLNLKKNIIRLQAHIRRRQQLQTYQKMKKAALVIQIHFRAYISAKEV--LASYQKTRSAVIVLQSACRRMQARKKFLHIL-------TAVVKIQSYYRAYASRRKFLRLKKATVKLQSIVRMKQARKQY 1702
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1250099437|ref|XP_022624787.1| (abnormal spindle-like microcephaly-associated protein [Seriola dumerili]) HSP 1 Score: 249.98 bits (637), Expect = 3.396e-64 Identity = 336/1282 (26.21%), Postives = 593/1282 (46.26%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFR----QTKARRRFLTMKRAAGVIHKWWKG-CLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLR--------------------------------IMADA-------QEELRQ--YSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQK----RFASMKWAATIIQRSWRHYR------------------FVQHLHERIQFRLLNQSATKIQSYWRMW----MSRRSYLRFQTEA---QEEL-----------EHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKG--W--IQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVA-RLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNR----------LCLERRIQACVRIQRGFRKFI---------QRCCLQRCLSERIALRHEA------------QERAWTESRSLAAILIQSHWRGWTQR----QRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLE--EQSEMRLRHQW-------------------ATKIQSLWRMRMARREFAQIQASAL----------EELK----NYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKA----------------------CIAQRRLVS-MRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAE------------MAGATIQRSM-------------------QMWV-----------VRKKFIRIRRAV-----------TVIQKHYRGYQV--RTAFKSDCKIKQTAL--------LPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKY-EPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKT-FALLWLLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERG---RRRNNYLPNSF--RPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
YLTL+ SV IQR +R + V E++ +++ + A +Q+ ++ + R+E+ RR +Q+AT+IQS ++ H + +F A++ +++++Q ++R Q K R +FL M+R+A V+ +G C+ R +++ + +AT IQ +K + + AF R I+ A + +RQ ++A++IQ +++H ERK +L L+ S L IQ +R A K + ++ AA ++Q ++R + F +H E ++F+ + SA IQ Y+R + R +L+ + A Q L +H +AT+IQA ++ Q A+K+ R +A VLQ + + W +Q + + +++A VLQ ++R K Q++ K+ H +A+ IQ ++ R+ YL +++ LAIQ+ YR+ VA + Q ++L AA +Q+A+R QVR+E R R++AA VIQS +R+++ + ++R ++CV ++ KF+ Q C+ IA +H A Q+ A+ R AA ++Q +R QR + Y + K+ I +Q RG I RR ++ +V VIQRA+R ++ K+ +QS + ++ ++ A +Q+ +R + R+E A+ +A EE+K SAI+IQ ++R CV +R KFL+ +++ I LQA + C QRR+ RE+A +QR R +L R E Y +AIT+Q+ R ARR R AA AE ++ IQR++ Q WV R+K + +RA+ +VIQ+ R + + R + +K AL L D P K+ ++R ++ + E+ KL N+T+ ALD L R + +++L LK+L+ TR S CC++++ ++ L+R CNRS+P MD+I+ + + +NL+KY + + V L ++ +ETL+++L YR+K+ D I+TK F L LL +R +++ LP ++ ++ R H ER ++ N + SF + +P +++P PK + P W +R+D ++ DP +A +MV + L++
Sbjct: 2000 YLTLKSSVLTIQRRYR--ATVAAKEQMQKHQRLRRAAVVLQAAYRGQQVRKEVARR---------HQAATVIQSVFRKHREEVKFQAMRLSAIIIQRYYRSCVLQRKQREKFLKMRRSAIVLQAALRGHCV-------RSNIAKKHMAATVIQANFKRHKQQSAFKRQHWAACVLQQRFRAQRWRNLQMKHFQNRRKAAIVLQAAYRGMKSRGNIRQSHHAASVIQRAYKAHCERKQYLTLKSSVLTIQRRYRATVAAKEQMQKHQRLRRAAVVLQAAYRGQQVRKEVARRHQAATMIQSVFKKH-REEVKFQAMRLSAIIIQRYYRAHVLQRLDREKFLKMRRSAIVLQAALRGHCVRSNIAKKHMAATVIQANFKRHKQQSAFKRQRWAACVLQQRFRAQRWRNLQMKHYHKCRKAAIVLQAAYRGMKSRQTI------KQSHYAASVIQRAYKAHCERRQYLTLKSSVLAIQRRYRATVAAKEQMQKHQRLRR-AAVVLQAAYRGQQVRKEVAR----RHQAATVIQSVFRKHREEVKFQAMRLSAIIIQRYYRSCVLQRKQREKFLKMRRSAIVLQAALRGHCVRSNIAKKHMAATVIQANFKRHKQQSAFKRQR-WAACVLQQRFRAQKQRNLQLKHYQEVTKAVINLQAAFRGMISRRIIKQRLKAVSVIQRAYRAYSQRKQYLNFKQSVLAIQQKYRATVAAKAQRTQYLEMRRAAIILQAAYRGQQVRKEVARRHHAATVIQSVFRKHREEVKFQAMRLSAIIIQRYYRSCVLQRQEREKFLKTKQSTIILQAAFRGWCVRREISRQHQIAIVIQSCWRCSVQRRIFQRKREAAVTLQRRIRAVQLGR--VERNNYIRKRHAAITLQTHGRAWIARRQARD----AAKAEKRLRFTSAVFHHLSAIKIQRALRAHWALESAKRQIHSVITVQRWVRSRQQRGRYLEDRRKVVTAQRAIKRWLARRHKAASVIQEAVRKFLLLRRQERVQEGIVKAQALWRGHRSRRLNDNP-------KVVKLRHRLRQVSAGVREEDKLCNKTSSALDYLLRYKHFSYILEALKNLETATRLSPECCERLVESG--ATNVIFTLIRCCNRSVPCMDVITFSIQILLNLSKYHKTTEAVYL--VENSVETLLDLLQRYREKAGDKVAEKGGSIFTKACFLLALLLQDKHRAVEVMKLPKVIDRIRSIYRLTARKHKMDAERTVIKQKMNASINGSFFVQATPRKSRP-APKFA--PEWVLRKDKLKDIVDPLMAIQMVADTLSI 3230 HSP 2 Score: 151.369 bits (381), Expect = 3.972e-33 Identity = 207/775 (26.71%), Postives = 363/775 (46.84%), Query Frame = 0
Query: 57 RLKLALEL--KRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQT----KARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWR------HYRFVQHLHERIQ---------------FRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELE--HCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL----AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-----NRLC-LERRIQACVRIQRGFRKFIQRCCLQRCLSERI-ALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRT--------------AFKSDCKIKQ 761
R K+A EL K++++A +IQ+ ++ H + ++ AL+ A V+Q +R T K + F ++ AA +I W+G +RI + ++ AT IQ Y++ R A ++ +A +IQ +R++ RKA+L+ R + + +Q+ FR + + AAT+IQ S R Y +Q IQ +R L Q+ KIQ+ +R + R E+L+ H +A IQAQ+R+ AY ++C+AI++Q + + + R Q + + K +A V+Q ++R K + K MH++AT +Q ++ + R+ +L + A L Q+ YR+ + + +LE L A +Q+A+R VR++ ++ + AA++IQS +R+YQ RLC +QA R + R+ + +R + + A H + R + R AA +IQ ++ +R++Y+ L+ S + +Q++ R + ++ ++R R + V+Q A+R + K E+ RHQ AT IQS++R RE + QA L SAI+IQ ++R CV QR KFL++RR+ I LQA + + + +A +IQ ++RH+ + +K +A +Q +R + R++QM K F R+A V+Q YRG + R A+K+ C+ KQ
Sbjct: 1531 RGKVARELLKKQHRAAAVIQAAFRRHAAQRRYLALRKAVAVIQQKYRATILARKTMKDFEALRNAALLIQAIWRG------RADRIRIENWHQRATLIQAYYR---------RHQVQAVYRSKKAAAVVIQRHYRAYVAGEEMRKAYLYKRAACVTLQAGFRGMRVRTELKKKQQAATVIQSSVRMFLCRKRYFLLQSAAIIIQSRYRALLLCKAQQNEYRELKQATIKIQAVYRGFRVR-----------EDLKKKHNAARAIQAQFRMHRMRMAYLAIKCAAIIIQERYRAKMLRDQQLQGYRTMKSAAVVIQAAYRGHKARR------KVTEMHRAATVLQRKFLTIRDRKRFLAVKAAALVCQQRYRA----VTMARKDRLEYLSKHRAVICLQAAYRGYNVRKQ----LRIQRTAAVMIQSHFRKYQQKIYYKRLCWAANVVQARYRANKDMREKMHALSAKRKAAVVLQAAFHGMKCRRIIKQRHQAASVIQRAYKAHCERKQYLTLKSSVLTIQRRYRATVAAKEQMQKHQRLRRAAVVLQAAYRGQQVRK------EVARRHQAATVIQSVFR---KHREEVKFQAMRL------SAIIIQRYYRSCVLQRKQREKFLKMRRSAIVLQAALRGHCVRSNIAKKHMAATVIQANFKRHK------QQSAFKRQHWAACVLQQRFRAQR----------------------WRNLQM----KHFQNRRKAAIVLQAAYRGMKSRGNIRQSHHAASVIQRAYKAHCERKQ 2218 HSP 3 Score: 149.828 bits (377), Expect = 1.165e-32 Identity = 198/804 (24.63%), Postives = 367/804 (45.65%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKA----RRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWI----QLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSW------RRFKFVQSLA---------------HHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLI----------------------RHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
YL L+++V +IQ+ +R L ++ + + A IQ+ W R R + +R +E +Q ATLIQ++++ H + + + K A+VV+Q H+R A R+ +L + A + ++G + R L ++AT IQ +M+ R+ + L Q +A +IQS++R A L + Q+E+R+ +K A IQ +R +R + L ++ + +A IQ+ +RM R +YL + C+A +IQ ++R + QL+ Y+ M+ +A+V+QA +G RR+ R+A VLQR + +RF V++ A L++ H++ +Q +R + R+ + A + IQ ++R + ++ + K AA +Q+ +R N+ RE+ + + +AA+V+Q+A+ + R +++R QA IQR ++ +R++Y+ L+ S + +Q++ R + ++ ++R R + V+Q A+R + K E+ RHQ AT IQS++R RE + QA L SAI+IQ ++R CV QR KFL++RR+ I LQA + + + +A +IQ ++RH+ R+L +++ ++ ++AI +Q+ +R K+R + R H A + IQR+ + RK+++ ++ +V IQ+ YR
Sbjct: 1562 YLALRKAVAVIQQKYRATILARKTMKDF--EALRNAALLIQAIW---RGRADRIR-----IE-NWHQRATLIQAYYRRHQVQAVYRSKKAAAVVIQRHYRAYVAGEEMRKAYLYKRAACVTLQAGFRG------MRVRTELKKKQQAATVIQSSVRMFLCRKRYF---------LLQSAAIIIQSRYR------ALLLCKAQ----QNEYRE---------LKQATIKIQAVYRGFRVREDLKKK------HNAARAIQAQFRMHRMRMAYLAIK---------CAAIIIQERYRAKMLRDQQLQGYRTMKSAAVVIQAAYRGHKARRKVTEMHRAATVLQRKFLTIRDRKRFLAVKAAALVCQQRYRAVTMARKDRLEYLSKHRAVICLQAAYRGYNVRKQLRIQRTAAVMIQSHFRKYQQKIYY----KRLCWAANVVQARYRANKDMREKMHALSAKRKAAVVLQAAFHGMKCRRIIKQRHQAASVIQRA-------------------------------------------YKAHCERKQYLTLKSSVLTIQRRYRATVAAKEQMQKHQRLRRAAVVLQAAYRGQQVRK------EVARRHQAATVIQSVFR---KHREEVKFQAMRL------SAIIIQRYYRSCVLQRKQREKFLKMRRSAIVLQAALRGHCVRSNIAKKHMAATVIQANFKRHKQQSAFKRQHWAACVLQQRFRAQRWRNL-QMKHFQNRRKAAIVLQAAYRGMKSRGNIRQSHH-------AASVIQRAYKAHCERKQYLTLKSSVLTIQRRYRA 2235 HSP 4 Score: 149.058 bits (375), Expect = 2.192e-32 Identity = 214/891 (24.02%), Postives = 413/891 (46.35%), Query Frame = 0
Query: 1 MYLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQ---TKARRR-FLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA-------------QEELRQY-----SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRM----HQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVA-RLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQR-----------------------CLSERIALRHEA------------QERAWT--------------------------ESRSLAAILIQSHWRGW-----------------------TQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLI----------------------RHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
+Y + + + +IQR +R Y + + + L ++ C T +Q+ ++ R R EL K+ Q+AT+IQS + + R+++ L++A++++QS +R KA++ + +K+A I ++G ++ L ++ + +A IQ ++M R R A+L I A ++L+ Y +A +IQ+ +R H R+ + + +Q +F +KRF ++K AA + Q+ +R + +R+++ +++ +Q+ +R + R+ Q ++ +A +IQ+ +R + Q YK++ +A V+QA+ + R+ +++++A VLQ ++ H +K +R+ HQ+A+ IQ ++ R+ YL +++ L IQ+ YR+ VA + Q ++L AA +Q+A+R QVR+E R R++AA VIQS +R+++ + + + + IQR +R C LQR C+ IA +H A Q+ A+ ++R AAI++Q+ +RG +R++Y+ L+ S + +Q++ R + ++ ++R R + V+Q A+R + K E+ RHQ AT IQS+++ RE + QA L SAI+IQ ++R V R KFL++RR+ I LQA + + + +A +IQ ++RH+ R+L +++ Y ++AI +Q+ +R K+R+ + +H AAS IQR+ + R++++ ++ +V IQ+ YR
Sbjct: 1634 VYRSKKAAAVVIQRHYRAYVAGEEMRKAYLYKRA-ACVT-LQAGFRGMRVRTELK---------KKQQAATVIQSSVRMFLCRKRYFLLQSAAIIIQSRYRALLLCKAQQNEYRELKQATIKIQAVYRGFRVREDLKKK------HNAARAIQAQFRMHRMRMAYLAIKCAAIIIQERYRAKMLRDQQLQGYRTMKSAAVVIQAAYRGHKARRKVTEMHRAATVLQRKFLTIRDRKRFLAVKAAALVCQQRYRAVTMARK--DRLEYLSKHRAVICLQAAYRGYNVRK---------QLRIQRTAAVMIQSHFRKYQQKIYYKRLCWAANVVQARYRANKDMREKMHALSAKRKAAVVLQAAF----------HGMKCRRIIKQRHQAASVIQRAYKAHCERKQYLTLKSSVLTIQRRYRATVAAKEQMQKHQRLRR-AAVVLQAAYRGQQVRKEVAR----RHQAATVIQSVFRKHREEVKFQAMRLSAIIIQRYYRS----CVLQRKQREKFLKMRRSAIVLQAALRGHCVRSNIAKKHMAATVIQANFKRHKQQSAFKRQHWAACVLQQRFRAQRWRNLQMKHFQNRRKAAIVLQAAYRGMKSRGNIRQSHHAASVIQRAYKAHCERKQYLTLKSSVLTIQRRYRATVAAKEQMQKHQRLRRAAVVLQAAYRGQQVRK------EVARRHQAATMIQSVFK---KHREEVKFQAMRL------SAIIIQRYYRAHVLQRLDREKFLKMRRSAIVLQAALRGHCVRSNIAKKHMAATVIQANFKRHKQQSAFKRQRWAACVLQQRFRAQRWRNL-QMKHYHKCRKAAIVLQAAYRGMKSRQTIKQ-SHYAAS------VIQRAYKAHCERRQYLTLKSSVLAIQRRYRA 2454 HSP 5 Score: 142.124 bits (357), Expect = 3.007e-30 Identity = 205/797 (25.72%), Postives = 369/797 (46.30%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQ--IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQRE--------QFCALK-TASVVLQSHFRQTKARR---RFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLR---HSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI---QACVRIQRGFRKFIQRCCLQRCLSE--RIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVR----RDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQK--YKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEM--------------------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
R+ +IQ +WR+Y L + L+ L ER + Q ++SF + R++++ NQ+A +IQS W+ ++ R Q AL+ A+ ++Q +R+ KA++ K V KW+K + + +RI +A +IQ +++M R + +I + SA IQ+Q+R H++R F L+ HS + IQS FR + +K+ A M+ A IQR +R V+ ER F L +A IQ+ +R ++R + +H +A +IQA +R + Y +R + V+Q + + I R+ FE+ + +A ++Q WR A ++ + HQ AT IQ +R Q + Y + A + IQ++YR++VA + + A T+Q+ +R +VR E ++ + +AA VIQS+ R + LC +R A + IQ +R + Q E + ++ +A R + L AA IQ+ +R R Y+ ++ ++I++Q++ R ++R + Y +S+ VIQ A+R +++ E H+ AT +Q + R+ F ++A+AL + Y A+ + R ++L R I LQA + +++L R +A +IQ +R+++ QK YK + +A +Q+ +R +K R H A + A + IQR+ + RK+++ ++ +V IQ+ YR
Sbjct: 1297 RAARVIQGAWRKYRLKKDLQ-LYKERNVAAVKIQLVVRSFLQKRRAKRQ-------------NQAAVIIQSVWRGYVARNRLRLKKEAQLRALQHKAATIIQRGYRRWKAQKTEKENCAAKAIQAVFKKWYK-----EKMAKRIA------AAVRIQSWYRMQRCLHQYRKI---------KRSAVFIQAQYRGHAQRHCFKMLKLQQHSAIVIQSAFRGHAVRKQVARMRCATITIQRWFRAT--VRRDGERQMFVRLRYAAVTIQAVYRGKVARELLKK---------QHRAAAVIQAAFRRHAAQRRYLALRKAVAVIQQKYRATILARKTMKDFEALRNAALLIQAIWR------GRADRIRIENWHQRATLIQAYYRRHQVQAVYRSKKAAAVVIQRHYRAYVAGEEMRKAYLYKRAACVTLQAGFRGMRVRTE----LKKKQQAATVIQSSVRMF---LCRKRYFLLQSAAIIIQSRYRALLLCKAQQNEYRELKQATIKIQAVYRGFRVREDLKKKHNAARAIQAQFRMHRMRMAYLAIKCAAIIIQERYRAKMLRDQQLQGYRTMKSAAVVIQAAYRGHKARRKVTEM------HRAATVLQRKFLTIRDRKRFLAVKAAALVCQQRYRAVTMARK-----DRLEYLSKHRAVICLQAAYRGYNVRKQLRIQRTAAVMIQSHFRKYQ--------QKIYYKRLCWAANVVQARYRANKDMREKMHALSAKRKAAVVLQAAFHGMKCRRIIKQRHQAASVIQRAYKAHCERKQYLTLKSSVLTIQRRYRA 2016 HSP 6 Score: 106.301 bits (264), Expect = 2.907e-19 Identity = 127/447 (28.41%), Postives = 222/447 (49.66%), Query Frame = 0
Query: 325 SQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVA--RLAFQAERKLESL---AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQ-YQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLR---KSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLV----SMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
++ R+ARV+Q +WR+++ + L +K + +A +IQ R + ++ R A + IQ +R +VA RL + E +L +L AAT IQ +RR + ++ + N AA IQ+ +++ Y+ ++ +RI A VRIQ +R +QRCL + ++ +A+ IQ+ +RG QR + L+ S+I++Q RG VR+ R R + IQR W R + + E Q +RLR+ T IQ+++R ++AR L + ++ +A +IQ+ +R + ++L LR+ +Q +A I R+ + ++R +A +IQ WR A+ + + Q A IQ+ +R H+ + YR S + A IQR + +V +RK ++ R A +Q +RG +VRT K
Sbjct: 1294 NETRAARVIQGAWRKYRLKKDLQ---LYKERNVAAVKIQLVVRSFLQKRRAKRQNQAAVIIQSVWRGYVARNRLRLKKEAQLRALQHKAATIIQRGYRRWKAQK-----TEKENCAAKAIQAVFKKWYKEKMA--KRIAAAVRIQSWYR-------MQRCLHQYRKIKR-------------SAVFIQAQYRGHAQRHCFKMLKLQQHSAIVIQSAFRGHAVRKQVARMRCATITIQR-WFRATVRRDGERQMFVRLRYAAVT-IQAVYRGKVARE---------LLKKQHRAAAVIQAAFRRHAAQRRYLALRKAVAVIQQKYRATILARKTMKDFEALRNAALLIQAIWRGR------ADRIRIENWHQRATLIQAYYRRHQVQAVYR-------SKKAAAVVIQRHYRAYVAGEEMRKAYLYKRAACVTLQAGFRGMRVRTELK 1686 HSP 7 Score: 76.2554 bits (186), Expect = 3.479e-10 Identity = 95/338 (28.11%), Postives = 167/338 (49.41%), Query Frame = 0
Query: 427 RIIQTRNE--AALVIQSAWRQYQNR----LCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRY-----IGLR----KSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRG--KFLRLRR-TCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
R++ RNE AA VIQ AWR+Y+ + L ER + A V+IQ R F+Q+ RA +++ AA++IQS WRG+ R R LR K++ ++Q+ R W ++ E+ + + IQ ++++ + +M R A +IQS +RM+ ++ +I+ SA+ IQ+ +RG QR K L+L++ + I +Q+ + ++++ MR + IQR +R +R E Q + + +A+TIQ+++R AR L A A IQ + + +++++ +R+AV VIQ+ YR
Sbjct: 1288 RLLDLRNETRAARVIQGAWRKYRLKKDLQLYKERNV-AAVKIQLVVRSFLQK------------------RRAKRQNQ--AAVIIQSVWRGYVARNRLRLKKEAQLRALQHKAATIIQRGYRRWKAQKT-EKENCAAKAIQAVFKKW-------YKEKMAKRIAAAVRIQSWYRMQRCLHQYRKIK---------RSAVFIQAQYRGHAQRHCFKMLKLQQHSAIVIQSAFRGHAVRKQVARMRCATITIQRWFR--ATVRRDGERQMFVRLRYAAVTIQAVYRGKVAR-------ELLKKQHRAAAVIQAAFRRHAAQRRYLALRKAVAVIQQKYRA 1578
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1209975622|ref|XP_021380828.1| (abnormal spindle-like microcephaly-associated protein [Lonchura striata domestica]) HSP 1 Score: 249.21 bits (635), Expect = 5.569e-64 Identity = 297/1127 (26.35%), Postives = 534/1127 (47.38%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILER--KINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAF--LRIMADAQEELRQYSATLIQSQWRSH----SERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHL-------HERIQFRLLNQSATK---------------------------------IQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWI----QRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQ-VRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTE---SRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWI----VRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY-----------RHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLWLLA-SSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERG---RRRNNYLPNSFRPSPAQAKP-KMPKLS-LCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
Y +Q + +IQR +R RL ++ +E + + AT IQ ++ + R++ + + + +AT++Q ++KA +R+++ +LK A++V Q +R R+ + +++RAA I ++G ++ L M+ +A+ IQ ++M R R+A+ +RI +A LIQ+ +R + ++RK +L +R+S L IQ+ +R A++ + +A +IQ S+R Y R + L +R + ++ ++AT+ IQS+ RM M RR +LR + +A +IQ+ +R W Y +R SA+ +Q+ +G + QR Q+ +Q+++ V+Q ++R K K R ++A +IQ+ +M R+ Y++ + A + +Q YY H + + + R+ AA +Q +R + V+++R +QTR LV Q+ R Y R + + ++IQ +R + R + + + R +AW E S A ++IQSH R R R++ ++ ++ +Q+ R +R+ + +RS+ IQ A+R++ + L E +HQ A IQS +R RR++ Q +A+A ++IQ H R G +Q K+ + RR I+LQA + + ++++ ++ R+ IQRA+R H L LA+ Q S + IQS +R RR + R L A A IQR+ + ++ R++ R+ + Q +RGY R K+ TA K +R+ + ANE + E+ KLGNRT++A+D L + + ++++L LK L+V TR S CC+ + R + + L+R CNRS+P MD+I + V +N++KYE + + E A++ ++TL+++L +YR K+ D I+TKT LL +L+ S R +I +P + +K R H ER + N L S S P ++ +S + P W +R+D ++ DP A MV++ L +
Sbjct: 2382 YRKVQWAAQLIQRRYR----AHRLRKIAVEHYTSLKKAATCIQRAFRDMQVRKQ---------QQEMHHAATVVQKNFKAFRERQRYLSLKAATLVFQRRYRALALARQHALEYHSLRRAAIHIQAVYRGVRVRRSLKH------MHSAASTIQASYRMLRDRRAYQNMRI-----------AAMLIQNYYRCYLKGKNQRKKYLTMRNSVLVIQAAYRGMRARQELKLLHVSALVIQSSYRMYVQRRCYKQLCWAATVTQQRFRAKMAREAATRNYAEIRKAVICLQAAFRARKARQLYKANVAARHIQSFLRMCMERRRFLR---------QKSAAIMIQSVFRCWRARTCYVLLRSSAVAVQSWYRGCLRARAQRAQYLAQRQAIVVIQSAFRAMK-------ARKTARQLRAARKIQSFLQMALQRRRYIQLRAATVTLQSYYLMHKCKSQYMSYRR----AAVVLQRHYRSHLIVKQQRMAYLQTRRNVVLV-QATVRGYIERKRFHKMKASTIKIQAAYRGYKARQWVNKMRAARAIQVWFPGHKAWKEYPLSVLRATLVIQSHLRAKQLRTRFLKMKSCALTIQRAWRATCTARRLRQQFLATRSAAVKIQLAYRQYRARRLLRE------KHQAACLIQSAYRGFKTRRKYVQQKAAA---------VIIQKHLRAWQEGRLQFVKYNKTRRAVIKLQAFIRGYLVRKKISEQKQKKRLLYFAAAAYHHISAIKIQRAYRIH-LTLKLAQTQ-----ISSVLIIQSWFRAKIQRRRFLRDYQRVVVLQRALRGWLNRRSEAAAVIQRNARAFLARRRRRRLAVGIIKFQALWRGYSWR-------KMTDTA-------------KTRALRRSLEKANEKSREENKLGNRTSIAIDHLLKYKHLSYILAALKHLEVATRLSPLCCENM--AQSRAIFSIFLLIRSCNRSVPCMDVIRYSVQVLLNVSKYERTTQAVYE-AENSIDTLLDLLQMYRGKAGDKVSEKGGSIFTKTCCLLAILSKDSKRALEIRGMPRTVSCIQSLYKLTARKHRMDAERTLVKEKTNTALGGS---SSVPVTPLRIKTVSRIKPDWVLRKDNMQEIMDPLQAILMVMDTLGI 3410 HSP 2 Score: 175.637 bits (444), Expect = 1.170e-40 Identity = 212/846 (25.06%), Postives = 399/846 (47.16%), Query Frame = 0
Query: 12 IQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLN---ERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHC---------------SATLIQAQWRVWIQLKAYKQ----MRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR-------------------------------RFKFVQSLAHHLK-------WK------RMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWR----------RFALIKRLEEQSE-----------MRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHL---------------------AELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQV 749
IQ+ +R Y L + E L+++ +Q+ ++ ++R EL R+ K +A +IQS W+ ++++F LK + +LQSH R+ + +R+ +K AA VI ++ + K +R+ L+ + + Y M RQA + LR S IQS +R++ RK F +LR +T++IQ+ + +K + +++ A +QR +R R E +R L + +IQ+ R ++ R+ R++ EA L+ C +AT+IQ +R + + ++Q +R +A+ LQA +G+ R++ + + R+A +Q ++R R F+ + A L W+ R H +AT+IQ+ +R + A + + ++A L IQ++YR+ V + E AA +Q+ WR VRR IQ ++ A +IQS +R + N+L ++ QA + IQ+ +R + C+++ Q + ++++ A +++QS +RG T R++ L K++ +Q + ++V+++Y R RS+ IQR +R R+ +KR+ Q + +R HQ A IQ++++M ++ ++ +A+ + Y AI + G VQR K+L L+++ + LQA + ++ L +M +SA IIQ +R H+ R+ A++ KY ++ + + IQ+ +R K RR R + ++ A IQR + ++ RK F+ I+ A V+Q+ YR ++
Sbjct: 1472 IQQYYRAYKLAKGERESYLQKR--AAVIVLQAAFRGMKAR-ELYRQAK---------AACVIQSLWRMKREKQRFLQLKKSVTMLQSHVRRYQQVKRYKEIKNAASVIQTRYRAHVAAKKAGAAFQRVRLAAIVLQS----AYRGMQARRQACI---------LR--SVIKIQSSFRAYVARKRFKNLRDATVKIQALAKMRQVRKHYCALREAVLYVQRRYRSRRCALQFKE--DYRKLKRGCIRIQALVRGYLVRKQIQRWR-EAAILLQACYRMKRDRQRYLSIYSAATVIQQHYRACKKTQCHRQEFLQVRKAAVCLQAAYRGYKTRKKLKLECRAAIKIQTAFRAHAARVKHKAMVQASIVIQRWYRNCKGGKRQRLNFLMTRAAVLSLQAAFRGWRVRKQIQRQHVAATKIQSTFRKFMAVKKFRLVKHAVLTIQRHYRATVLGQRQRQEYIHLRNAAVCLQALWRGKVVRR----TIQKKHHLATIIQSYYRMHINQLKYKKLRQATMVIQKYYRAY----CMKK-----------TQRLIYLQTKA-AVLVLQSAYRGMTVRRQLNKLNKAATTIQAAFKSYLVKKEYGRLRSAAIAIQRRYRAITHAKCQRQRYLSLKRVTVQVQAIYRGVRVRRQVRCMHQAAVCIQAMFKMYCMSIKYQSMRMAAIRIQRQYRAICL-----GQVQRKKYLELKKSVVILQAAYRGMKVRQDLKTMHQSAAIIQSYYRMHKQQRNFRKLLLATRQIQQWFRACKERDAQVHKYMIVKNAVLHIQAAFRGMKTRRLLRTMN-------VSAAIIQRRFRTFLERKCFLSIKSAAIVVQRKYRATKI 2255 HSP 3 Score: 157.918 bits (398), Expect = 3.558e-35 Identity = 211/855 (24.68%), Postives = 390/855 (45.61%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLE-----------------ELILERKI---NQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR------------QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQ-----HLHERIQFRLLN---------------QSATKIQSYWRMWMSRRSYLRF---------------QTEAQEELEHCSATLIQAQWRVWIQLK----AYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNR----------LCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEM---------------------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
R+ +IQ +WR+Y + + L+ + R+I + A IQ W+ + +R L + LE RN+SAT+IQ++W+ + R ++ L+ + +Q+ R K+ + + A I + + K +R ++ SA IQ ++ WR Q++ R ++ R+ +A +IQS +R H + K +LH++ S ++IQ+ +R A+ + + IQ+ +R Y+ + +L +R +L ++A IQS WRM ++ +L+ Q + +E+++ +A++IQ ++R + K A++++R +AIVLQ+ +G RRQ RS +Q S+R + ++K + + +IQ +M Q R+ Y + A L +Q+ YRS L F+ + + IQ+ R VR++ IQ EAA+++Q+ +R ++R +++ +AC + Q ++F+Q CL +A R + + L AAI IQ+ +R R ++ + ++SI++Q+ R G R ++ +R++V +Q A+R + + K+++ Q H ATKIQS +R MA ++F L ++ + IQ H+R V QR +++ LR + LQAL + + +R + A IIQ +R H I L KYK + Q+ + IQ +R + ++ R L +L A + A TIQ + + ++V+K++ R+R A IQ+ YR
Sbjct: 1223 RAARLIQAAWRKYRMKRELKLSQERDRAARIIQKSAMNFLARRRILRKEEAAIFIQKHWRGYLARMTLFNLKRAKLEEARNKSATVIQAYWRRYSARRRYLQLRHCIIFVQARIRMVKSVAAYKQIVGATVTIQRHLRATKLAKINRQRYQ--ILKSSALTIQSAFRRWRKYKIQQKIKAALVIQSYFRKWRSSKLAKRKRAALVIQSWYRMHRDLKQYLHVKQSVIKIQAWYRGQLARHVYQENRAKIVTIQQYYRAYKLAKGERESYLQKRAAVIVLQAAFRGMKARELYRQAKAACVIQSLWRMKREKQRFLQLKKSVTMLQSHVRRYQQVKRYKEIKN-AASVIQTRYRAHVAAKKAGAAFQRVRLAAIVLQSAYRGMQARRQ-ACILRSVIKIQSSFRAY------VARKRFKNLRDATVKIQALAKMRQVRKHYCALREAVLYVQRRYRSRRCALQFKEDYRKLKRGCIRIQALVRGYLVRKQ----IQRWREAAILLQACYRMKRDRQRYLSIYSAATVIQQHYRACKKTQCHRQEFLQVRKAAVCL--------QAAYRGYKTRKKLKLECRAAIKIQTAFRAHAARVKHKAMVQASIVIQRWYRNCKGGKRQRLNFLMTRAAVLSLQAAFRGWRVRKQIQRQ------HVAATKIQSTFRKFMAVKKF---------RLVKHAVLTIQRHYRATVLGQRQRQEYIHLRNAAVCLQALWRGKVVRRTIQKKHHLATIIQSYYRMH--INQL----KYKKLRQATMVIQKYYRAYCMKKTQR-LIYLQTKAAVLVLQSAYRGMTVRRQLNKLNKAATTIQAAFKSYLVKKEYGRLRSAAIAIQRRYRA 2033 HSP 4 Score: 138.658 bits (348), Expect = 3.036e-29 Identity = 186/723 (25.73%), Postives = 331/723 (45.78%), Query Frame = 0
Query: 69 SATLIQSHWKAHIQREQFCALKTASVVLQSHFRQT----KARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMW-------RGRQAFLRI--------MADAQE--ELRQYSATLI-QSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLH-ERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGW----TQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARR-HYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
+AT IQS ++ + ++F +K A + +Q H+R T + R+ ++ ++ AA + W+G + ++ + ++ HL AT IQ Y++M + RQA + I M Q L+ +A L+ QS +R + R+ L + IQ+ F+ + +K + ++ AA IQR YR + H +R ++ L + ++Q+ Y + Q H +A IQA ++++ Y+ MR +AI +Q Q + G +QR+++ K+S +LQ ++R K Q L K MHQSA IQ+ +RM + ++++ + A IQ+++R+ R A + + A IQ+A+R + RR +++T N +A +IQ R FR F++R C S AAI++Q +R +QRQ+Y+ L +++++Q RG++VR+ +M+ HQ AT IQ++ RM + + QA L ++++IQ +R G +R K+L+L + + LQA + + L RE+A IQR +R +R H Y+ + +A IQ +R H+ R+ H T L + A IQR+ + VRK+ + A TV+QK+++ ++ R + S
Sbjct: 1854 AATKIQSTFRKFMAVKKFRLVKHAVLTIQRHYRATVLGQRQRQEYIHLRNAAVCLQALWRGKVVRRTIQKKHHL------ATIIQSYYRMHINQLKYKKLRQATMVIQKYYRAYCMKKTQRLIYLQTKAAVLVLQSAYRGMTVRRQLNKLNKAATTIQAAFKSYLVKKEYGRLRSAAIAIQR---RYRAITHAKCQRQRYLSLKRVTVQVQAI---------YRGVRVRRQVRCMHQAAVCIQAMFKMYCMSIKYQSMRMAAIRIQRQYRAICLGQVQRKKYLELKKSVVILQAAYRGMKVRQDL------KTMHQSAAIIQSYYRMHKQQRNFRKLLLATRQIQQWFRACKERDAQVHKYMIVKNAVLHIQAAFRGMKTRR----LLRTMNVSAAIIQ-----------------------RRFRTFLERKCFLSIKS--------------------AAIVVQRKYRATKIANSQRQKYLSLLNAAVIIQSAYRGFVVRK-----------------------------KMQQMHQAATVIQAMLRM---HKIYTSYQALRL------ASVIIQQRYRAYREGKREREKYLKLCNSVLVLQAAYRGMKIRCFLKRQREAALTIQRNYRMYRQYCH------YRKVQWAAQLIQRRYRAHRLRKIAVEHYTSL----KKAATCIQRAFRDMQVRKQQQEMHHAATVVQKNFKAFRERQRYLS 2457 HSP 5 Score: 135.191 bits (339), Expect = 3.553e-28 Identity = 182/689 (26.42%), Postives = 305/689 (44.27%), Query Frame = 0
Query: 133 NERIHLSLMNRSATKIQGYWKMWRGRQ------------AFLRIMADAQEELRQYS--ATLIQSQWRSHSERKAFLHLRHSTLR----IQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLL---NQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGW----IQRRQFESQKRSARVLQ---RSWRRFKFVQSLAHHL-------KWK-----RMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQV-RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSE-MRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRL---------------IRHLAELQKYKVMTQ------SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCK 758
NE+ + L+N + + + G M +L + +LRQ + A LIQ+ WR + ++ L L R IQ + A++R + AA IQ+ WR Y L + +L N+SAT IQ+YWR + +RR YL +L HC +QA+ R+ + AYKQ+ + + +Q ++ I R++++ K SA +Q R WR++K Q + L KW+ + ++A IQ+ +RM + + YL + + + IQ +YR +AR +Q R TIQ +R ++ + ER+ +Q R A +V+Q+A+R + R + ACV IQS WR ++QR++ L+KS M+Q VR + + Y+ +++ VIQ +R K+ + +RL A +QS +R ARR QA L S I IQS +R V R +F LR +++QALAK ++ ++RE+ +QR +R R IR A ++ Y V Q +AI +Q+ +RM + R+ Y + A + +++ R++F+++R+A +Q YRGY+ R K +C+
Sbjct: 1167 NEKQNFQLINAAVSDLGGIPAMIHHADMSNTIPDEKVVITYLSFLCSRLLDLRQETRAARLIQAAWRKYRMKRE-LKLSQERDRAARIIQKSAMNFLARRRILRKEEAAIFIQKHWRGYLARMTLFNLKRAKLEEARNKSATVIQAYWRRYSARRRYL--------QLRHC-IIFVQARIRMVKSVAAYKQIVGATVTIQRHLRATKLAKINRQRYQILKSSALTIQSAFRRWRKYKIQQKIKAALVIQSYFRKWRSSKLAKRKRAALVIQSWYRMHRDLKQYLHVKQSVIKIQAWYRGQLARHVYQENRA----KIVTIQQYYRAYKLAKGERESYLQKR-AAVIVLQAAFRGMKARELYRQAKAACV--------------------------------------------IQSLWRMKREKQRFLQLKKSVTMLQSHVRRYQQVKRYKEIKNAASVIQTRYRAHVAAKKAGAAFQRVRL---AAIVLQSAYRGMQARR-----QACILR-----SVIKIQSSFRAYVARKRFKNLRDATVKIQALAKMRQVRKHYCALREAVLYVQRRYRSRRCALQFKEDYRKLKRGCIRIQALVRGYLVRKQIQRWREAAILLQACYRMKRDRQRYLSIYSAATVIQQHYRACKKTQ---CHRQEFLQVRKAAVCLQAAYRGYKTRKKLKLECR 1780 HSP 6 Score: 133.265 bits (334), Expect = 1.643e-27 Identity = 214/910 (23.52%), Postives = 412/910 (45.27%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQEL---LRRLKLALEL---------KRNQSATL-----IQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKG--CLFQKHLNER------IHLSLMNR-------------SATKIQGYWKMWRGRQAFLRIMADA-----------------QEELR-QYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSH----VARLAFQAERKLESLAAT-TIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQ-RCCLQRCLS-ERIALRHEAQERAWT----------------------------ESRSLAAILIQSHWR----GWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWR---------------------------------RFALIKR-----------LEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNY------------------SAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR 750
+L L++SV ++Q RRY V+R +E I A+ IQ+ ++ H + ++ +R++LA + R Q+ L IQS ++A++ R++F L+ A+V +Q+ + + R+ + ++ A + + ++ C Q + R I + + R +A +Q ++M R RQ +L I + A QE L+ + +A +Q+ +R + RK + ++IQ+ FR +A+ + +M A+ +IQR +R+ + + +R+ F + + +Q+ +R W R+ Q + +H +AT IQ+ +R ++ +K ++ ++ + + +Q A V G QR+++ + +A LQ WR +++ ++ H AT IQ+ +RM + Y + + A + IQKYYR++ RL + L++ AA +QSA+R VRR+ ++ N+AA IQ+A++ Y + R A + IQR +R +C QR LS +R+ ++ +A R +S +AAI IQ +R G QR++Y+ L+KS +++Q RG VR+D + S +IQ +R ++ ++K ++ + +R + A IQ +R + R+ F I+++A+ + Y +A++IQS +RG V R K ++ + +QA+ + ++R ++ IIQ+ +R +R + E +KY + S + +Q+ +R K R L E A TIQR+ +M+ + +++ A +IQ+ YR +++R
Sbjct: 1534 FLQLKKSVTMLQSHVRRYQQVKRYKE------IKNAASVIQTRYRAHVAAKKAGAAFQRVRLAAIVLQSAYRGMQARRQACILRSVIKIQSSFRAYVARKRFKNLRDATVKIQALAKMRQVRKHYCALREAVLYVQRRYRSRRCALQFKEDYRKLKRGCIRIQALVRGYLVRKQIQRWREAAILLQACYRMKRDRQRYLSIYSAATVIQQHYRACKKTQCHRQEFLQVRKAAVCLQAAYRGYKTRKKLKLECRAAIKIQTAFRAHAARVKHKAMVQASIVIQRWYRNCKGGKR--QRLNFLMTRAAVLSLQAAFRGWRVRK---------QIQRQHVAATKIQSTFRKFMAVKKFRLVKHAVLTIQRHYRATVLGQRQRQEYIHLRNAAVCLQALWRGKVVRRTI------QKKHHLATIIQSYYRMHINQLKYKKLRQATMVIQKYYRAYCMKKTQRLIY-----LQTKAAVLVLQSAYRGMTVRRQLNKL----NKAATTIQAAFKSYLVKKEYGRLRSAAIAIQRRYRAITHAKCQRQRYLSLKRVTVQVQAIYRGVRVRRQVRCMHQAAVCIQAMFKMYCMSIKYQSMRMAAIRIQRQYRAICLGQVQRKKYLELKKSVVILQAAYRGMKVRQDLKTMHQSAAIIQSYYRMHKQQRNFRKLLLATRQIQQWFRACKERDAQVHKYMIVKNAVLHIQAAFRGMKTRRLLRTMNVSAAIIQRRFRTFLERKCFLSIKSAAIVVQRKYRATKIANSQRQKYLSLLNAAVIIQSAYRGFVVRKKMQQMHQAATVIQAMLRMHKIYTSYQALRLASVIIQQRYRAYREGKR--EREKYLKLCNSVLVLQAAYRGMKIR------CFLKRQRE-AALTIQRNYRMYRQYCHYRKVQWAAQLIQRRYRAHRLR 2402 HSP 7 Score: 130.954 bits (328), Expect = 7.526e-27 Identity = 187/720 (25.97%), Postives = 318/720 (44.17%), Query Frame = 0
Query: 144 SATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMW------------MSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKF-----------------VQSLAHHLKWKRMH---QSATRIQTQWRMWQARQSYLR-----------------------TQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRE-------------------RQRIIQTRNEAALVIQ--SAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQ-----RCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMAR-REFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWR------RHRLIRHLA---------------ELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
+A IQ +W+ + R + EE R SAT+IQ+ WR +S R+ +L LRH + +Q+ R + + + A IQR R + + +R Q +L SA IQS +R W + +SY R ++ +A +IQ+ +R+ LK Y ++ S I +QA +G + R ++ + +Q+ +R +K +Q+ +K + ++ ++A IQ+ WRM + +Q +L+ +NA IQ YR+HVA A + LAA +QSA+R Q RR+ R+R R +A + IQ + RQ + C R +A + +QR +R +RC LQ R L +R +R +A R + + + AAIL+Q+ +R RQRY+ + ++ ++Q+ R R+++ + R + +Q A+R + K+L +L + A KIQ+ +R AR + A +QAS I+IQ +R C QR FL R + LQA + ++++ +A IQ +R + RL++H + Q+Y + +A+ +Q+LWR RR + HLA IQ +M + + K+ ++R+A VIQK+YR Y
Sbjct: 1273 AAIFIQKHWRGYLARMTLFNLKRAKLEEARNKSATVIQAYWRRYSARRRYLQLRHCIIFVQARIRMVKSVAAYKQIVGATVTIQRHLRATKLAKINRQRYQ--ILKSSALTIQSAFRRWRKYKIQQKIKAALVIQSYFRKWRSSKLAKRKRAALVIQSWYRMHRDLKQYLHVKQSVIKIQAWYRGQLARHVYQENRAKIVTIQQYYRAYKLAKGERESYLQKRAAVIVLQAAFRGMKARELYRQAKAACVIQSLWRMKREKQRFLQLKKSVTMLQSHVRRYQQVKRYKEIKNAASVIQTRYRAHVAAKKAGAAFQRVRLAAIVLQSAYRGMQARRQACILRSVIKIQSSFRAYVARKRFKNLR-DATVKIQALAKMRQVRKHYCALR--EAVLYVQRRYRS--RRCALQFKEDYRKL-KRGCIRIQALVRGYLVRKQIQRWREAAILLQACYRMKRDRQRYLSIYSAATVIQQHYRACKKTQCHRQEFLQVRKAAVCLQAAYRGYKTRKKL------KLECRAAIKIQTAFRAHAARVKHKAMVQAS----------IVIQRWYRNCKGGKRQRLNFLMTRAAVLSLQAAFRGWRVRKQIQRQHVAATKIQSTFRKFMAVKKFRLVKHAVLTIQRHYRATVLGQRQRQEYIHLRNAAVCLQALWRGKVVRRTIQKKHHLA-------TIIQSYYRMHINQLKYKKLRQATMVIQKYYRAY 1961
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|676274023|gb|KFO28611.1| (Abnormal spindle-like microcephaly-associated protein like protein, partial [Fukomys damarensis]) HSP 1 Score: 248.825 bits (634), Expect = 6.240e-64 Identity = 312/1161 (26.87%), Postives = 544/1161 (46.86%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWR--RYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFR---QTKARR-RFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWR--------------------HYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGW----IQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQ--AERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNR-----------------------LCL----------ERRIQ--ACVRIQRGFRKF-IQRCCLQRCLSERI-------------------ALRHEAQERAWTESRSL-----AAILIQSHWRGW--TQRQR--YIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQ----ALAKACIAQR----RLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMA-----------GATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLW-LLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLS--LCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
Y T + S IIQR +R + + QR E L L++ A ++Q+ ++ R R + + L +A ATLI++ +K H R ++ AL+ A+++++ +R Q K +R ++LT +A + ++G ++ L +R SAT IQ Y++ +R + F +L++ + IQ ++R+ ER + LRHS + IQS FR A++ AA +IQR +R YR + L + +Q R ++ +IQS +R WM R+ + H +ATLIQA +R+ ++ + +AI++Q + + +QR F Q SA V+Q +++ K + L + H++AT IQ+ +RM++ Y + Q A IQ+ YR++ + A Q A +K E TT Q R Q IQ ++EAA++IQ +R ++ R +C+ E +Q A + IQR FRK I++ Q+C + RI A+ + RAW + AA+++Q+H+R + T+RQR Y+ +R S+I++Q ++G+I +R +++ +SS IQ AWR++ K L + + A KIQ+ +R R ARR++ L LK + +IQ + ++R +FL++R + I +Q A+ A IA+ +++ R RI IQRA++RH +++ K S I IQ +R ++ + H + A + IQ++++ +++ K+ + +T IQ +RGY R K+DC KI+ +R + + ++ E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+E+ ++ + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L IYR+K D I+TKT LL LL ++NR + + ++ +K R H +R + P+ P A+ KP ++ L P W +R D I +P A +MV++ + +
Sbjct: 1942 YATYRASALIIQRWYRDVKNANHQRKEYLTLKK----AAIKVQAVYRGMRVRGHI-QHLHMA--------ATLIKATFKMHQSRVRYRALRKAAIMIERRYRAYHQGKIQREKYLTTLKAVKTLQASFRGARVRQALRKR------QISATLIQSYYRRYRQQTYF--------NKLKKVTKA-IQQRYRAAKERNIQLQRYTKLRHSVICIQSAFRGMKARRHLKVRHLAAILIQRRFRTLMVRRKFLSLKKTVIWIQRKYRAKRDLEQFLQLR---KAVIQIQSSYRGWMVRKKLQKM---------HRAATLIQATFRMHRNCVTFQTWKHAAILIQQHYRKYRAAKLQRENFIRQWDSAVVIQAAYKGTKARRVL------REKHRAATVIQSTYRMYRQYCFYKKLQWATTVIQEKYRANKKQKALQHKACKKEEICIQTTFQDINTRKQ--------IQKQHEAAIIIQKHFRAFKTRRQYLYLRATEISVTLTAPSTQAVICVPSSHRGFQEAEYHLQSWAALTIQRAFRKMMIRKLNTQKCAALRIQPFLQMAVHRRRFIQQRRAAVTLQHCFRAWQARKQFLLYRKAAVVLQNHYRAFLSTKRQRQCYLQIRSSAIIIQAVMKGFIQKRKFQQIKSSTIKIQGAWRKYKAKKYL-------CKVKAACKIQAWYRCRRARRQY-------LALLK--AVQIIQGCFYTKLERTRFLKMRTSAIIIQRKWRAMLLARIAREHLMIKILEQRAKIRILHFAAAAYYHLSALRIQRAYKRHMTMKNA------KKQINSVICIQRWFRAKLQQKKFIEKYHSTVKTKHALQECLNQQNRAASVIQKAVRRFLLCKRQEKFNTRITKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQLVSKEIREENKLYKRTALALHDLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAESGAISKVFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCIDTLLELLQIYREKPGDKVADKGGSIFTKTCCLLAVLLKTANRASDVRSRSKVVDRIYSLYKLTARKHKVSTDRIFYKQKKNPSVGIPCTAE-KPGRTRIVSRLKPDWILRRDNIEEVTNPLQAIQMVMDTVGI 3002 HSP 2 Score: 186.422 bits (472), Expect = 5.176e-44 Identity = 218/832 (26.20%), Postives = 403/832 (48.44%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY---------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSR------------RSYLRFQTEAQEELEHCSATLI----QAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL------------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCL--SERIALRHEAQERAWTE----SRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L+ +I IN A Q IQ W+ ++++LL K LE +N+SA +IQ +W+ + R++F LK SV+LQS R A R + + A I + W+ + +K ER ++ SA IQ ++ W+ R+ L+ A Q R++ SA +IQS +R H E + ++++R + IQ FR + QK + + + IQ+ +R Y ++ ER + + ++A ++Q+ +R W +R +SY R + Q++ S I QA R QL+ YK+M+ +AIV+Q + +I R+ ++ + + VLQ ++R + + ++HH+ + + + Q+ +M QAR+ YLR + A L IQ+++RS +AE + + T+Q+ +R VR++ ++ + +AA+ +QS +R + R + +A IQ +R + R +R +R A +A R + +S+AA+ IQ+ +RG++ R +Y + +S++ +Q+ R + + RRD+ ++R++V +Q A+R + + K+++++ HQ A KIQS++RM AR++F ++ + L +IQ H R G Q ++++LR + LQA K +R++ SA IIQ +R H + +K+K++ ++ + IQ +R + R H +L A + T+Q + + VRK+ +A IQ YR Y + + +
Sbjct: 1149 RAARLIQTTWRKYKLKKDLKHHQERDKAARIIQSAVINFLAKQRLKKEANAALIIQKCWRRALAQRKLLMLTKEKLEKIQNKSAAVIQGYWRRYFARKRFLKLKYYSVILQSRIRMITAVRSYKRCRWATVTIQRCWRAYVRRKQDQER--YKMLKSSALIIQSRFRRWKQRKMRLQTKAVVLLQRAFREWHFRKRAKEKSAVVIQSWYRMHKELQRYIYIRSCVVIIQRRFRCFQVQKLYKRKRESVLTIQKYYRAY--LKGKAERANYSQIREAAIRLQAAFRRWKARNLQRQIRAACVLQSYWRVR---QDKFRFLSLKKIVIKLQAHVRRHQQLQKYKKMKKAAIVIQTHFRAYISARKVLASYQKTRSAVIVLQSAYRGMQ-ARKMSHHILTSVIKIQSYYRAYISRKTFLSLKSCTVKFQSIVKMKQARRQYLRLKEAALFIQQWFRSQKMAARKRAEYLQKRESCITLQAFFRGYLVRKQ----MRLQRKAAVSLQSYFRMRKVRQHYLKIYKAITVIQNYYRAYKARVNQRRNFLQVKRAATCLQAAYRGYKVRQIIKQSIAALKIQTAFRGYSNRIKYQFVLQSTVKIQRWYRAYKIVCDTRRDFLKTRAAVISLQSAYRGWKVRKQIQKE------HQAAIKIQSVFRMIKARKQFRLLKTATL---------VIQQHLRALAAGRKQCLEYIKLRSAVVMLQAAWKGKSLRRQIKKQHNSAVIIQSYYRMH------VQQKKWKIVKKAVLLIQMYYRAYSVGRE-EHQLYLRKKASI--VTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYTTQKKYAT 1944 HSP 3 Score: 149.058 bits (375), Expect = 1.860e-32 Identity = 202/761 (26.54%), Postives = 361/761 (47.44%), Query Frame = 0
Query: 65 KRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKM------WRGR-------QAFLRIMADAQEELRQY-----SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHL-HERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAW--------------------RQYQNRLCLERRIQ---ACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGW----TQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQ---RAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARRE-------FAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRA------WRRHRLIRHLAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
K +Q+A IQS ++ R+QF LKTA++V+Q H R A R+ ++ ++ A ++ WKG ++ + ++ + SA IQ Y++M W+ Q + R + +EE + Y S +QS +R RK + + IQS++R ++ QK++A+ + +A IIQR W YR V++ H+R ++ L ++A K+Q+ +R M R +++ H +ATLI+A +++ Y+ +R +AI+++ A +G IQR ++ + ++ + LQ S+R + Q+L ++ SAT IQ+ +R ++ + + + + AIQ+ YR+ R + Q KL + IQSA+R + RR ++ R+ AA++IQ + R+Y+ + LE+ +Q A ++IQ +R ++ R LQ+ R A +A R + AAILIQ H+R + QR+ +I S++++Q +G RR + VIQ R +R++ K+L+ + + A K Q + + ++E F I + ++ +AI+IQ H+R R ++L LR T I + A + A ++ + S R Q A W + R ++ K+ TQ +A+ IQ +M RR + A T+Q + W RK+F+ R+A V+Q HYR +
Sbjct: 1775 KEHQAAIKIQSVFRMIKARKQFRLLKTATLVIQQHLRALAAGRKQCLEYIKLRSAVVMLQAAWKGKSLRRQIKKQ------HNSAVIIQSYYRMHVQQKKWKIVKKAVLLIQMYYRAYSVGREEHQLYLRKKASIVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYTTQKKYATYRASALIIQR-W--YRDVKNANHQRKEYLTLKKAAIKVQAVYR-GMRVRGHIQHL--------HMAATLIKATFKMHQSRVRYRALRKAAIMIERRYRAYHQGKIQREKYLTTLKAVKTLQASFRGARVRQAL------RKRQISATLIQSYYRRYRQQTYFNKLKKVTKAIQQRYRAAKERNIQLQRYTKLRH-SVICIQSAFRGMKARRH----LKVRHLAAILIQRRFRTLMVRRKFLSLKKTVIWIQRKYRAKRDLEQFLQLRKAVIQIQSSYRGWMVRKKLQKM--HRAATLIQATFRMHRNCVTFQTWKHAAILIQQHYRKYRAAKLQRENFIRQWDSAVVIQAAYKGTKARRVLREKHRAATVIQSTYRMYRQYCFYKKLQWATTVIQEKYRANKKQKALQHKACKKEEICIQTTFQDINTRKQIQKQHEAAIIIQKHFRAFKTRRQYLYLRATEISVTLTAPSTQA---VICVPSSHRGFQEAEYHLQSWAALTIQRAFRKMMIRKLNTQKCAALRIQPFLQMAVHRRRF-------IQQRRAAVTLQHCFRAWQARKQFLLYRKAAVVLQNHYRAF 2494
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|731240666|ref|XP_010633716.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein [Fukomys damarensis]) HSP 1 Score: 248.825 bits (634), Expect = 6.951e-64 Identity = 311/1161 (26.79%), Postives = 542/1161 (46.68%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWR--RYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFR---QTKARR-RFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWR--------------------HYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGW----IQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQ--AERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNR-----------------------LCL----------ERRIQ--ACVRIQRGFRKF-IQRCCLQRCLSERI-------------------ALRHEAQERAWTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQ----ALAKACIAQR----RLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMA-----------GATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLW-LLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLS--LCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
Y T + S IIQR +R + + QR E L L++ A ++Q+ ++ R R + + L +A ATLI++ +K H R ++ AL+ A+++++ +R Q K +R ++LT +A + ++G ++ L +R SAT IQ Y++ +R + F +L++ + IQ ++R+ ER + LRHS + IQS FR A++ AA +IQR +R YR + L + +Q R ++ +IQS +R WM R+ + H +ATLIQA +R+ ++ + +AI++Q + + +QR F Q SA V+Q +++ K + L + H++AT IQ+ +RM++ Y + Q A IQ+ YR++ + A Q A +K E TT Q R Q IQ ++EAA++IQ +R ++ R +C+ E +Q A + IQR FRK I++ Q+C + RI A+ + RAW + AA+++Q+H+R + QRQ Y+ +R S+I++Q ++G+I +R +++ +SS IQ AWR++ K L + + A KIQ+ +R R ARR++ L LK + +IQ + ++R +FL++R + I +Q A+ A IA+ +++ R RI IQRA++RH +++ K S I IQ +R ++ + H + A + IQ++++ +++ K+ + +T IQ +RGY R K+DC KI+ +R + + ++ E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+E+ ++ + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L IYR+K D I+TKT LL LL ++NR + + ++ +K R H +R + P+ P A+ KP ++ L P W +R D I +P A +MV++ + +
Sbjct: 2084 YATYRASALIIQRWYRDVKNANHQRKEYLTLKK----AAIKVQAVYRGMRVRGHI-QHLHMA--------ATLIKATFKMHQSRVRYRALRKAAIMIERRYRAYHQGKIQREKYLTTLKAVKTLQASFRGARVRQALRKR------QISATLIQSYYRRYRQQTYF--------NKLKKVTKA-IQQRYRAAKERNIQLQRYTKLRHSVICIQSAFRGMKARRHLKVRHLAAILIQRRFRTLMVRRKFLSLKKTVIWIQRKYRAKRDLEQFLQLR---KAVIQIQSSYRGWMVRKKLQKM---------HRAATLIQATFRMHRNCVTFQTWKHAAILIQQHYRKYRAAKLQRENFIRQWDSAVVIQAAYKGTKARRVL------REKHRAATVIQSTYRMYRQYCFYKKLQWATTVIQEKYRANKKQKALQHKACKKEEICIQTTFQDINTRKQ--------IQKQHEAAIIIQKHFRAFKTRRQYLYLRATEISVTLTAPSTQAVICVPSSHRGFQEAEYHLQSWAALTIQRAFRKMMIRKLNTQKCAALRIQPFLQMAVHRRRFIQQRRAAVTLQHCFRAWQARKQFLLYRKAAVVLQNHYRAFLSTKRQRQCYLQIRSSAIIIQAVMKGFIQKRKFQQIKSSTIKIQGAWRKYKAKKYL-------CKVKAACKIQAWYRCRRARRQY-------LALLK--AVQIIQGCFYTKLERTRFLKMRTSAIIIQRKWRAMLLARIAREHLMIKILEQRAKIRILHFAAAAYYHLSALRIQRAYKRHMTMKNA------KKQINSVICIQRWFRAKLQQKKFIEKYHSTVKTKHALQECLNQQNRAASVIQKAVRRFLLCKRQEKFNTRITKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQLVSKEIREENKLYKRTALALHDLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAESGAISKVFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCIDTLLELLQIYREKPGDKVADKGGSIFTKTCCLLAVLLKTANRASDVRSRSKVVDRIYSLYKLTARKHKVSTDRIFYKQKKNPSVGIPCTAE-KPGRTRIVSRLKPDWILRRDNIEEVTNPLQAIQMVMDTVGI 3144 HSP 2 Score: 186.422 bits (472), Expect = 5.211e-44 Identity = 218/832 (26.20%), Postives = 403/832 (48.44%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY---------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSR------------RSYLRFQTEAQEELEHCSATLI----QAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL------------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCL--SERIALRHEAQERAWTE----SRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L+ +I IN A Q IQ W+ ++++LL K LE +N+SA +IQ +W+ + R++F LK SV+LQS R A R + + A I + W+ + +K ER ++ SA IQ ++ W+ R+ L+ A Q R++ SA +IQS +R H E + ++++R + IQ FR + QK + + + IQ+ +R Y ++ ER + + ++A ++Q+ +R W +R +SY R + Q++ S I QA R QL+ YK+M+ +AIV+Q + +I R+ ++ + + VLQ ++R + + ++HH+ + + + Q+ +M QAR+ YLR + A L IQ+++RS +AE + + T+Q+ +R VR++ ++ + +AA+ +QS +R + R + +A IQ +R + R +R +R A +A R + +S+AA+ IQ+ +RG++ R +Y + +S++ +Q+ R + + RRD+ ++R++V +Q A+R + + K+++++ HQ A KIQS++RM AR++F ++ + L +IQ H R G Q ++++LR + LQA K +R++ SA IIQ +R H + +K+K++ ++ + IQ +R + R H +L A + T+Q + + VRK+ +A IQ YR Y + + +
Sbjct: 1291 RAARLIQTTWRKYKLKKDLKHHQERDKAARIIQSAVINFLAKQRLKKEANAALIIQKCWRRALAQRKLLMLTKEKLEKIQNKSAAVIQGYWRRYFARKRFLKLKYYSVILQSRIRMITAVRSYKRCRWATVTIQRCWRAYVRRKQDQER--YKMLKSSALIIQSRFRRWKQRKMRLQTKAVVLLQRAFREWHFRKRAKEKSAVVIQSWYRMHKELQRYIYIRSCVVIIQRRFRCFQVQKLYKRKRESVLTIQKYYRAY--LKGKAERANYSQIREAAIRLQAAFRRWKARNLQRQIRAACVLQSYWRVR---QDKFRFLSLKKIVIKLQAHVRRHQQLQKYKKMKKAAIVIQTHFRAYISARKVLASYQKTRSAVIVLQSAYRGMQ-ARKMSHHILTSVIKIQSYYRAYISRKTFLSLKSCTVKFQSIVKMKQARRQYLRLKEAALFIQQWFRSQKMAARKRAEYLQKRESCITLQAFFRGYLVRKQ----MRLQRKAAVSLQSYFRMRKVRQHYLKIYKAITVIQNYYRAYKARVNQRRNFLQVKRAATCLQAAYRGYKVRQIIKQSIAALKIQTAFRGYSNRIKYQFVLQSTVKIQRWYRAYKIVCDTRRDFLKTRAAVISLQSAYRGWKVRKQIQKE------HQAAIKIQSVFRMIKARKQFRLLKTATL---------VIQQHLRALAAGRKQCLEYIKLRSAVVMLQAAWKGKSLRRQIKKQHNSAVIIQSYYRMH------VQQKKWKIVKKAVLLIQMYYRAYSVGRE-EHQLYLRKKASI--VTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYTTQKKYAT 2086 HSP 3 Score: 149.058 bits (375), Expect = 2.159e-32 Identity = 202/761 (26.54%), Postives = 361/761 (47.44%), Query Frame = 0
Query: 65 KRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKM------WRGR-------QAFLRIMADAQEELRQY-----SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHL-HERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAW--------------------RQYQNRLCLERRIQ---ACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGW----TQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQ---RAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARRE-------FAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRA------WRRHRLIRHLAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
K +Q+A IQS ++ R+QF LKTA++V+Q H R A R+ ++ ++ A ++ WKG ++ + ++ + SA IQ Y++M W+ Q + R + +EE + Y S +QS +R RK + + IQS++R ++ QK++A+ + +A IIQR W YR V++ H+R ++ L ++A K+Q+ +R M R +++ H +ATLI+A +++ Y+ +R +AI+++ A +G IQR ++ + ++ + LQ S+R + Q+L ++ SAT IQ+ +R ++ + + + + AIQ+ YR+ R + Q KL + IQSA+R + RR ++ R+ AA++IQ + R+Y+ + LE+ +Q A ++IQ +R ++ R LQ+ R A +A R + AAILIQ H+R + QR+ +I S++++Q +G RR + VIQ R +R++ K+L+ + + A K Q + + ++E F I + ++ +AI+IQ H+R R ++L LR T I + A + A ++ + S R Q A W + R ++ K+ TQ +A+ IQ +M RR + A T+Q + W RK+F+ R+A V+Q HYR +
Sbjct: 1917 KEHQAAIKIQSVFRMIKARKQFRLLKTATLVIQQHLRALAAGRKQCLEYIKLRSAVVMLQAAWKGKSLRRQIKKQ------HNSAVIIQSYYRMHVQQKKWKIVKKAVLLIQMYYRAYSVGREEHQLYLRKKASIVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYTTQKKYATYRASALIIQR-W--YRDVKNANHQRKEYLTLKKAAIKVQAVYR-GMRVRGHIQHL--------HMAATLIKATFKMHQSRVRYRALRKAAIMIERRYRAYHQGKIQREKYLTTLKAVKTLQASFRGARVRQAL------RKRQISATLIQSYYRRYRQQTYFNKLKKVTKAIQQRYRAAKERNIQLQRYTKLRH-SVICIQSAFRGMKARRH----LKVRHLAAILIQRRFRTLMVRRKFLSLKKTVIWIQRKYRAKRDLEQFLQLRKAVIQIQSSYRGWMVRKKLQKM--HRAATLIQATFRMHRNCVTFQTWKHAAILIQQHYRKYRAAKLQRENFIRQWDSAVVIQAAYKGTKARRVLREKHRAATVIQSTYRMYRQYCFYKKLQWATTVIQEKYRANKKQKALQHKACKKEEICIQTTFQDINTRKQIQKQHEAAIIIQKHFRAFKTRRQYLYLRATEISVTLTAPSTQA---VICVPSSHRGFQEAEYHLQSWAALTIQRAFRKMMIRKLNTQKCAALRIQPFLQMAVHRRRF-------IQQRRAAVTLQHCFRAWQARKQFLLYRKAAVVLQNHYRAF 2636
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1239909891|ref|XP_022276460.1| (abnormal spindle-like microcephaly-associated protein homolog isoform X2 [Canis lupus familiaris]) HSP 1 Score: 248.054 bits (632), Expect = 1.043e-63 Identity = 272/1044 (26.05%), Postives = 510/1044 (48.85%), Query Frame = 0
Query: 40 QIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKA----RRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAF----------------LRIMADAQEELRQYSATLI--QSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLW--RMHKARRHYRHLTHLAASAEM---------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLW-LLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERG---RRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
++Q+F + H R+++ L+R Q+A +QS+++ +R+ + + A++V+Q+++R KA R+ FL +KRA + ++G ++ + ++ + +A KIQ ++ +R R+ + R + D + + + A +I Q +R RK R + +RIQS FR AQK+F +K AA +IQ+ R + +R+++ L ++A ++QS W+ RR Q + +H A +IQ+ +R+++Q K +K M+ +A ++Q A G QR+ + K +A VLQ ++R K + K K +++A IQ+ +R ++ +++Y + + + IQ++YR ++A ++ +L A IQ+ +R +VRR + + + AA VIQ+ ++ +Q ++ + A V IQ +R + R L H+ + AA IQ+ +R W R+ Y+ + K+ ++Q + RR + R+S +IQR WR + E M RHQ A IQ+ +R R+ F + +++AL ++ Y I++ G QR K++ L+++ + LQAL + + ++R++ R R+ IQRA++RH +++ + + I IQ + R+ + R ++ + L + E+ A + IQ++++ +++RKK + A++ IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRSIP M++I + V +N+AKYE + + + ++ ++TL+++L +YR+K D I+TKT LL LL ++NR + + ++ +K R H ER ++ N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 1727 KLQAFVRGHLVRKQI--------RLQR-QAAISLQSYFRMRKKRQYYLEIYKATLVIQNYYRAYKAQVNQRKNFLQVKRAVTCLQAAYRGYKVRQLIKQQ------SIAALKIQTAFRGYRERKKYQYVLQSTIKIQRWYRTCRTVRDVRTQFLKTRAAVISLQCAFRGWKVRKQIRRERQAAVRIQSAFRMAKAQKQFKLLKTAALVIQQHLRAW--TAGKRQRMEYIELREAALRLQSTWKGKRVRR---------QVQKQHKCAVIIQSNYRMYVQQKKWKIMKKAARLIQMYYRAYSIGRKQRQLYLKTKAAAVVLQSAYRSMKVRK------KIKECNRAAVTIQSTYRAYKTKKNYTNCRASAIIIQRWYRG--TKIANHQRKEYLNLKKTAVKIQAIYRGIRVRRHNRHL----HMAATVIQAMFKMHQAKMRYHKMRTAAVIIQAVWRSYKARKYL-----------HQVK----------AACKIQAWYRYWKARKDYLAVLKAVKIIQGCFYTKLERRRFLNVRASTIIIQRKWRAILSGRIACEHFLMIKRHQAACLIQANFRRYKGRQVFLRQKSAAL-TIQRY----IRARKAGKCQRIKYVELKKSTVVLQALVRGWLVRKRILEQRTKIRLLHFTAAAYYHLSALKIQRAYKRHMAMKNANK------QVNAVICIQRWFRTRLQQKRFAQKYPSILTSQHEVPECMSQQNRAASVIQKAVRRFLLRKKQEKFNNAISRIQSLWRGYSWRK--KNDC------------------TKIKAIRLSLQLVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAVSKIFV-LIRSCNRSIPCMEVIRYAVQVLLNVAKYEKTTAAVSD-VENCIDTLLDLLQMYREKPGDKVADKGGSIFTKTCCLLAVLLKTTNRASSVRSKSKVVDRIYSLYKLTARKHKMNTERTLYKQKMNSSISTPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 2675 HSP 2 Score: 167.548 bits (423), Expect = 3.975e-38 Identity = 224/861 (26.02%), Postives = 407/861 (47.27%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLE-----------------ELILERKINQ---CATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMAD---------------AQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHER-------IQFRLL--------NQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWR----RFKFVQSLAHHLK-------------WKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLA----------------FQA---------ERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCK 758
R+ +IQ +WR+Y L ++ + +R++ + A IQ +W+ ++++LL K LE +N+SA++IQ +W+ + R+QF L+ S++LQS R A + A I + W+ L +KH +R ++ S IQ ++ W+ R+ L+I A A+EE SA +IQS +R H E + ++ +R + IQ+ FR AQK + K A IQ+ ++ Y +L +R FR + +++A +QSYWRM R +L + T +QAQ R QL+ Y++++ +A+V+Q + ++ ++ ++ + + VLQ ++R R KF+ L +K + R+ + ++Q+ +M Q R+ YL + A L IQ++YRS A+LA QA + +L+ AA ++QS +R +R++RQ ++ +A LVIQ+ +R Y+ ++ + ++++R CLQ A + R + +S+AA+ IQ+ +RG+ +R++Y + +S+I +Q+ R RD + ++R++V +Q A+R + + K ++R Q A +IQS +RM A+++F ++ +AL +IQ H R G QR +++ LR +RLQ+ K +R++ + A IIQ +R + + +K+K+M ++A IQ +R + R R L +A + + RSM+ VRKK RA IQ YR Y+ + + ++C+
Sbjct: 1261 RAARLIQTTWRKYKLKTDMKRHQEQDKAARIIQSAIINFLTKRRLKKEISAALAIQKYWRRFLAQRKLLMLKKEKLEKVQNESASIIQRYWRRYSTRKQFLKLRYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRASLRRKHDQQR--YKMLKSSCLIIQSMFRRWKRRKMQLQIKATRVLQRAFREWHVRKRAKEE---KSAIVIQSWYRMHKELRKYVQIRSCVVIIQTRFRCLQAQKLYKRKKEAILTIQKYYKAYLKGKMERTNYLQKRAAAIRLQTAFRRMKARNLYRQSRAACVLQSYWRMRQDRFRFLNLKK---------ITTKLQAQVRKHQQLQKYRKIKKAALVIQIHFRAYVSAKKVLASYQKTRSAVLVLQSAYRGMQARKKFIHILTSIIKIQSCYRAYISRKRFLRLKNATVKLQSIVKMRQTRKRYLHWRAASLFIQRWYRS--AKLAALKRHQYVQMRESCIKLQAFVRGHLVRKQIRLQRQAAISLQSYFR---MRKKRQYYLEIY-KATLVIQNYYRAYKAQVNQRKNF---LQVKRAV------TCLQ-------AAYRGYKVRQLIKQQSIAALKIQTAFRGYRERKKYQYVLQSTIKIQRWYRTCRTVRDVRTQFLKTRAAVISLQCAFRGWKVRK------QIRRERQAAVRIQSAFRMAKAQKQFKLLKTAAL---------VIQQHLRAWTAGKRQRMEYIELREAALRLQSTWKGKRVRRQVQKQHKCAVIIQSNYRMY------VQQKKWKIMKKAARLIQMYYRAYSIGRKQRQLYLKTKAAAVVLQSAYRSMK---VRKKIKECNRAAVTIQSTYRAYKTKKNY-TNCR 2060 HSP 3 Score: 132.494 bits (332), Expect = 2.295e-27 Identity = 182/719 (25.31%), Postives = 329/719 (45.76%), Query Frame = 0
Query: 85 QFCALKTASVVLQSHFRQTKAR---RRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEEL--------------EHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAF--------------------QAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSL----AAILIQSHWR----GWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
C A+ ++Q+ +R+ K + +R +AA +I L ++ L + I +L IQ YW+ + ++ L + + E+++ SA++IQ WR +S RK FL LR+ ++ +QS R A + WA IQR WR ++ H++ ++++L S IQS +R W R+ ++ Q +A L E SA +IQ+ +R+ +L+ Y Q+R +++Q + + ++ ++ +K + +Q+ ++ +++ + + +A R+QT +R +AR Y +++ AC+ +Q Y+R R F Q RK++ AA IQ +R ++ Q A LV+QSA+R Q R + + ++IQ +R +I R R + + L+ + R T R L A++ IQ +R +R +Y+ +R+S I +Q VRG +VR+ ++RL+ Q A +QS +RMR R+ + +I + L +IQ+++R QR FL+++R LQA + ++ + +A IQ A+R +R E +KY+ + QS I IQ +R + R R T + A ++Q + + W VRK+ R R+A IQ +R + + FK
Sbjct: 1255 DLCKETRAARLIQTTWRKYKLKTDMKRHQEQDKAARIIQSAIINFLTKRRLKKEISAALA------IQKYWRRFLAQRKLLMLKKEKLEKVQNESASIIQRYWRRYSTRKQFLKLRYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAS--LRRKHDQQRYKMLKSSCLIIQSMFRRWKRRK--MQLQIKATRVLQRAFREWHVRKRAKEEKSAIVIQSWYRMHKELRKYVQIRSCVVIIQTRFRCLQAQKLYKRKKEAILTIQKYYK--AYLKGKMERTNYLQKRAAAIRLQTAFRRMKARNLYRQSRAACV-LQSYWRMRQDRFRFLNLKKITTKLQAQVRKHQQLQKYRKIKK-AALVIQIHFRAYVSAKKVLASYQKTRSAVLVLQSAYRGMQARKKFIHILTSIIKIQSCYRAYISRKRFLRLKNATVKLQSIVKMRQ-TRKRYLHWRAASLFIQRWYRSAKLAALKRHQYVQMRESCIKLQAFVRGHLVRK-----------------------------QIRLQRQAAISLQSYFRMRKKRQYYLEIYKATL---------VIQNYYRAYKAQVNQRKNFLQVKRAVTCLQAAYRGYKVRQLIKQQSIAALKIQTAFRGYR------ERKKYQYVLQSTIKIQRWYRTCRTVRDVR--TQFLKT-RAAVISLQCAFRGWKVRKQIRRERQAAVRIQSAFRMAKAQKQFK 1911 HSP 4 Score: 114.775 bits (286), Expect = 7.109e-22 Identity = 138/575 (24.00%), Postives = 263/575 (45.74%), Query Frame = 0
Query: 23 QRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQT----KARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA-------------QEELRQY-----SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAER--KLESLAATTIQSAWRRNQVRRERQRIIQTRNE--------------AALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFA 559
QR+E + ++ + A ++QS WK R R+++ K+++ A +IQS+++ ++Q++++ +K A+ ++Q ++R K R+ +L K AA V+ ++ +K + E NR+A IQ ++ ++ ++ + A A + ++Y +A IQ+ +R R+ HL + IQ+ F+ A+ R+ M+ AA IIQ WR Y+ ++LH+ ++A KIQ+++R W +R+ YL LKA K ++Q ++RR+F + + S ++QR WR + H + HQ+A IQ +R ++ RQ +LR ++A L IQ+Y R AR A + +R +E +T + A R + R+RI++ R + +AL IQ A++++ +++ A + IQR FR +Q+ + + +HE E ++R+ + I QK VR +++R+ E+ +++ IQ WR ++
Sbjct: 1933 QRMEYI----ELREAALRLQSTWKGKRVRRQVQ---------KQHKCAVIIQSNYRMYVQQKKWKIMKKAARLIQMYYRAYSIGRKQRQLYLKTKAAAVVLQSAYRSMKVRKKIKE------CNRAAVTIQSTYRAYKTKKNYTNCRASAIIIQRWYRGTKIANHQRKEYLNLKKTAVKIQAIYRGIRVRRHNRHLHMAATVIQAMFKMHQAKMRYHKMRTAAVIIQAVWRSYKARKYLHQV-------KAACKIQAWYRYWKARKDYLAV-------------------------LKAVK-------IIQGCFYTKLERRRFLNVRASTIIIQRKWRAILSGRIACEHFLMIKRHQAACLIQANFRRYKGRQVFLRQKSAALTIQRYIR---ARKAGKCQRIKYVELKKSTVVLQALVRGWL--VRKRILEQRTKIRLLHFTAAAYYHLSALKIQRAYKRHMAMKNANKQVNAVICIQRWFRTRLQQKRFAQKYPSILTSQHEVPECMSQQNRAASVI-------------------------QKAVRRFLLRKKQEKFNNAISRIQSLWRGYS 2419
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|449508025|ref|XP_002192393.2| (PREDICTED: abnormal spindle-like microcephaly-associated protein, partial [Taeniopygia guttata]) HSP 1 Score: 248.054 bits (632), Expect = 1.271e-63 Identity = 315/1257 (25.06%), Postives = 558/1257 (44.39%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLA-------------------------------------LELKR-----NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKA----RRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYW---KMWRGRQAFLRIMADAQEELRQY---------------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRF----VQH-----------------LHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA--------------QEELE---------------------------HCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATR-----IQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-------------------ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK--FIQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQ----------------------RY-IGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY-RHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKH-----------------------YRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLWLLA-SSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERG---RRRNNYLPNSFRPSPAQAKP-KMPKLS-LCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
YL L++SV I+Q ++R + Q L+ + +Q A IQS+++MH+ +Q R+L LA ++ +R N SA +IQ ++ ++R+ F ++K+A++V+Q +R TK R+++L++ AA +I ++G + +K + + M+++AT IQ K++ QA Q+ R Y S ++Q+ +R R R + L IQ +R + + ++WAA +IQR +R +R V+H + R Q + ++++AT +Q ++ + R+ YL + Q LE H +A+ IQA +R+ +AY+ MR +A+++Q +KG QR+++ + + S V+Q ++R + Q L K +H SA + IQ+ +R W+AR Y + +++ +A+Q +YR + A +A+ + A IQSA+R + R+ +R+R IQ R AA+ +QS + ++ + +A V +QR +R +++ + + R + +A R + E + + I IQ+ +RG+ RQ Y + + ++++++Q +R +R + + +S IQRAWR +RL +Q HQ A IQ+ +R RR+F Q +A+A ++IQ H R G VQ K+ + RR I+LQA + + ++++ ++ R+ IQRA+R H L LAE Q S + IQS +R RR + R + +QR+++ W+ R+ A TVIQ++ +RGY R K+ TA K +R+ + ANE + E+ KLGNRTA+A+D L + + ++++L LK L+V TR S CC+ + R + + L+R CNRS+P MD+I + V +N++KYE + + E A++ ++TL+++L +YR K+ D I+TKT LL +L+ S R +I +P + +K R H ER ++ N L S S P ++ +S + P W +R+D ++ DP A MV++ L +
Sbjct: 1986 YLELKKSVVILQAAYRGMKVRQDLKTM------HQSAAIIQSYYRMHK-QQRNFRKLLLATRQIQQWFRACKERDAQVHKYMIMKNAVLHIQAAFRGMKTRRLLRTMNVSAVIIQRRFRTFLERKHFLSIKSAAIVVQRKYRATKIANIQRQKYLSLLNAAVIIQSAYRGFVVRKKMQQ------MHQAATVIQAMLRMHKIYTSYQALRLASVIIQQRYRAYREGKREREKYLKLCNSVLVLQAAYRGMKIRHFLKRQREAALTIQRNYRMYRQYCHYRKVQWAAQLIQRRYRAHRLRKIAVEHYTSLKKAATCIQRAFRDMRVRKQQQEMHRAATVVQKNFKAFRERQRYLSLKAATLVFQRRYRALALARQHALEYHSLRRAAIHIQAVYRGVRVRRSLKHMHSAASTIQATYRMLRDRRAYQNMRIAAMLIQIYYRCYLKGKNQRKKYLTMRNSILVIQAAYRGMRARQEL------KLLHVSAVKSAAIMIQSVFRCWRARTCYAQLRSSAVAVQSWYRGCLRARAQRAQYLAQRQAIVVIQSAFRAMKARKRARQLRAARKIQSFLQMALQRRRYIQLR-AAAVTLQSYYLMHKCKSLYMSYRRAAVVLQRHYRSHLIVKQQRMAYLQTRRNVVLVQATVRGYIERKRFHKMKASTIKIQAAYRGYKARQWVNQMRAARAIQAWFPGHKAWKEYPLSVLRATLVIQSHLRAKQLRTRFLKMKSCALTIQRAWRATCAARRLRQQFLATRSHQAACLIQNTYRGFKTRRKFVQQKAAA---------VIIQKHLRAWQEGRVQFVKYNKTRRAVIKLQAFIRGYLVRKKISEQKQKKRLLYFAAAAYHHISAIKIQRAYRIH-LTLKLAETQ-----ISSVLIIQSWFRAKIQRRRFLRDYQRVV--------VLQRALRGWLNRRS-----EAATVIQRNARAFLARRRRRRLAVGIVKFQALWRGYSWR-------KMTDTA-------------KTRALRRSLEKANEKSREENKLGNRTAIAIDHLLKYKHLSYILAALKHLEVATRLSPLCCENM--AQSRAIFSVFLLIRSCNRSVPCMDVIRYSVQVLLNVSKYERTTRAVYE-AENSIDTLLDLLQMYRGKAGDKVSEKGGSIFTKTCCLLAILSKDSKRALEIRGMPRTVSCIQSLYKLTARKHRMDAERTLVKQKTNTALGGS---SSVPVTPLRIKTVSRIKPDWVLRKDNMQEIMDPLQAILMVMDTLGI 3168 HSP 2 Score: 153.295 bits (386), Expect = 8.635e-34 Identity = 218/865 (25.20%), Postives = 390/865 (45.09%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLE-----------------ELILERKI---NQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR------------QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQ-----HLHERIQFRLLN---------------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHC--------------SATLIQAQWRVWIQLK----AYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQ-RCCLQRCLSER-IALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEM---------------------AGATIQRSMQM-W---------VVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y + + L+ + R+I + A IQ W+ + +R L K LE RN+SAT+IQ++W+ + R ++ L+ + +Q+ R K+ + + A I + + K +R ++ SA IQ ++ WR Q++ R ++ R+ +A +IQS +R H + K +LH++ S ++IQ+ +R A+ + + IQ+ +R Y+ + +L +R +L ++A IQS WRM ++ +L+ + H +A++IQ ++R + K A++++R +AIVLQ+ +G RRQ RS +Q S+R + ++K + + +IQ +M Q R+ Y + A L +Q+ YRS L F+ + + IQ+ R VR++ IQ EAA+++Q+ +R ++R A IQ+ +R + RC Q L R A+ +A R + + L AAI IQ+ +R R ++ + + SI++Q+ R G R ++ +R++V +Q A+R + + K+++ Q H ATKIQS +R MA ++F L ++ + IQ H+R V QR +++ LR +RLQAL + + +R + A IIQ +R H I L KYK + Q+ + IQ +R + ++ R L +L A + A TIQ + + W V RK ++ ++++V ++Q YRG +VR K+
Sbjct: 1182 RAARLIQAAWRKYRMKRELKLSQERDRAARIIQKSAMNFLARRRILRKEKAAIFIQKHWRGYLARMTLFNLKKAKLEEARNKSATVIQAYWRRYSARRRYLQLRHCVIFVQARIRMVKSVAAYKQIVGATVTIQRHLRAAKLAK--IDRQRYQILKSSALTIQSAFRRWRKYKIQQKIKAALVIQSYFRKWQSSKLAKRKRAALVIQSWYRMHRDLKQYLHVKQSVIKIQAWYRCQLARHVYQKNRAKIVTIQQYYRAYKLAKGERECYLQKRAAVIVLQAAFRGMKARELYRQARAACVIQSLWRMKREKQRFLQLKKSVTMLQSHVRRYQQVKRYKEIKNAASVIQTRYRAHVAAKKANAAFQRVRLAAIVLQSAYRGMQARRQ-ACILRSVIKIQSSFRAY------VAQKRFKNLRDATVKIQALAKMRQVRKRYCALREAVLYVQRRYRSRRRALQFKEDYRKLKRGCVRIQALVRGYLVRKQ----IQRWREAAILLQACYRMKRDRRRYLSIYSAATVIQQRYRACKKTRCHRQEFLQVRKAAVCLQAAYRGYKTRKKLKLECRAAIKIQTAFRAHAARVKHKAMVQVSIVIQRWYRNCKGGKRQRLNFLMTRAAVLSLQAAFRGWRVRKQIQRQ------HVAATKIQSTFRKFMAVKKF---------RLVKHAVLTIQRHYRATVLGQRQRQEYIHLRNAAVRLQALWRGKVVRRTIQKKHNLATIIQSYYRMH--INQL----KYKKLRQATLVIQKYYRAYCMKKTQR-LIYLQIKAAVLVLQSAYRGMTVRRQLNKLNKAATTIQAAFNLTWQYRAICLGQVQRKTYLELKKSVVILQAAYRGMKVRQDLKT 2011 HSP 3 Score: 141.739 bits (356), Expect = 3.431e-30 Identity = 220/862 (25.52%), Postives = 392/862 (45.48%), Query Frame = 0
Query: 2 YLTLQRSVHIIQ---RSWRRYSLVQRLEE-LILER-----------KINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQ---TKARRRFLTMKRAAGVI-HKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA---QEELRQY-----------SATLIQSQWRSHSERK----AFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSY--------------------LRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRI--IQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWR----GWTQRQRYIGLRKSSIMVQKQVRGWIVRRD-----------------------YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKI-QSLWRMRMARREFAQIQ--ASALEELKN----YSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHL---------------------AELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQV 749
Y L+ S IQ R WR+Y + Q+++ L+++ K + A IQS+++MHR LK L +K QS IQ+ ++ + R + + V +Q ++R K R KRAA ++ ++G + R L R+A IQ W+M R +Q FL++ Q +R+Y +A++IQ+++R+H K AF +R + + +QS +R A +R A + + IQ S+R Y + +F+ L + KIQ+ +M R+ Y L+F+ + ++ C IQA R ++ K ++ R +AI+LQA + RR++ S +A V+Q+ +R K ++ H ++ ++ ++A +Q +R ++ R+ A + IQ +R+H AR+ +A + + + W RN +RQR+ + TR A L +Q+A+R ++ R ++R+ A +IQ FRKF+ + + ++H A + IQ H+R G QRQ YI LR +++ +Q RG +VRR Y++ R + VIQ+ +R + + K Q + L+ + A + QS +R RR+ ++ A+ ++ N Y AI + G VQR +L L+++ + LQA + ++ L +M +SA IIQ +R H+ R+ A++ KY +M + + IQ+ +R K RR R + ++ IQR + ++ RK F+ I+ A V+Q+ YR ++
Sbjct: 1331 YQILKSSALTIQSAFRRWRKYKIQQKIKAALVIQSYFRKWQSSKLAKRKRAALVIQSWYRMHRD-------LKQYLHVK--QSVIKIQAWYRCQLARHVYQKNRAKIVTIQQYYRAYKLAKGERECYLQKRAAVIVLQAAFRG------MKAR-ELYRQARAACVIQSLWRMKREKQRFLQLKKSVTMLQSHVRRYQQVKRYKEIKNAASVIQTRYRAHVAAKKANAAFQRVRLAAIVLQSAYRGMQA-RRQACILRSVIKIQSSFRAYV------AQKRFKNLRDATVKIQALAKMRQVRKRYCALREAVLYVQRRYRSRRRALQFKEDYRKLKRGC--VRIQALVRGYLVRKQIQRWREAAILLQACYRMKRDRRRYLSIYSAATVIQQRYRACK--KTRCHRQEFLQVRKAAVCLQAAYRGYKTRKKLKLECRAAIKIQTAFRAHAARVKHKA-----MVQVSIVIQRWYRNCKGGKRQRLNFLMTR-AAVLSLQAAFRGWRVRKQIQRQHVAATKIQSTFRKFM-------AVKKFRLVKH-------------AVLTIQRHYRATVLGQRQRQEYIHLRNAAVRLQALWRGKVVRRTIQKKHNLATIIQSYYRMHINQLKYKKLRQATLVIQKYYRAYCMKK---TQRLIYLQIKAAVLVLQSAYRGMTVRRQLNKLNKAATTIQAAFNLTWQYRAICL-----GQVQRKTYLELKKSVVILQAAYRGMKVRQDLKTMHQSAAIIQSYYRMHKQQRNFRKLLLATRQIQQWFRACKERDAQVHKYMIMKNAVLHIQAAFRGMKTRRLLRTMN-------VSAVIIQRRFRTFLERKHFLSIKSAAIVVQRKYRATKI 2124 HSP 4 Score: 121.709 bits (304), Expect = 5.229e-24 Identity = 157/620 (25.32%), Postives = 280/620 (45.16%), Query Frame = 0
Query: 143 RSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQ----ARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCK 758
++A IQ +W+ + R + EE R SAT+IQ+ WR +S R+ +L LRH + +Q+ R + + + A IQR R + + +R ++++L SA IQS +R W R Y + Q++++ +A +IQ+ +R W K K+ R +A+V+Q+ + +Q+ K+S +Q +W R + LA H+ K + T IQ +R ++ R+ YL+ + A + +Q +R AR ++ R AA IQS WR ++RE+QR +Q + + +QS R+YQ + A IQ +R + + A + LAAI++QS +RG R++ LR S I +Q R ++ ++ ++ R + KIQ+L +MR R+ + AL E Y +S R + + +L+R C+R+QAL + + ++++ RE+A ++Q +R R + ++Y + +A IQ +R K R + R++F+++R+A +Q YRGY+ R K +C+
Sbjct: 1231 KAAIFIQKHWRGYLARMTLFNLKKAKLEEARNKSATVIQAYWRRYSARRRYLQLRHCVIFVQARIRMVKSVAAYKQIVGATVTIQRHLRAAKLAK--IDRQRYQILKSSALTIQSAFRRW---RKY-----KIQQKIK--AALVIQSYFRKWQSSKLAKRKR-AALVIQSWYRMHRDLKQYLHVKQSVIKIQ-AWYRCQ----LARHVYQKNRAKIVT-IQQYYRAYKLAKGERECYLQKRAAVIVLQAAFRGMKARELYRQAR-----AACVIQSLWR---MKREKQRFLQLKKSVTM-LQSHVRRYQQVKRYKEIKNAASVIQTRYRAHVA----------------AKKANAAFQRVRLAAIVLQSAYRGMQARRQACILR-SVIKIQSSFRAYVAQKRFKNLRDAT-----------------------------VKIQALAKMRQVRKRYC-----ALREAVLYVQRRYRSRRRALQFKEDYRKLKRGCVRIQALVRGYLVRKQIQRWREAAILLQACYRMKR------DRRRYLSIYSAATVIQQRYRACKKTRCH--------------------------RQEFLQVRKAAVCLQAAYRGYKTRKKLKLECR 1739 HSP 5 Score: 78.1814 bits (191), Expect = 1.082e-10 Identity = 100/373 (26.81%), Postives = 185/373 (49.60%), Query Frame = 0
Query: 393 VARLAFQAERKL----ESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWR-------------MRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQ 748
+ L+F R L E+ AA IQ+AWR+ +++RE ++ Q R+ AA +IQ + + R + R+ +A + IQ+ +R ++ R L ++ E+R+ +A +IQ++WR ++ R+RY+ LR I VQ ++R Y++ + IQR R L K ++ Q L+ A IQS +R + + F + Q+S L + K +A++IQS +R ++L ++++ I++QA + +A+ R IQ+ +R ++L + E + Y + I +Q+ +R KAR YR A IQ +M +++F++++++VT++Q H R YQ
Sbjct: 1164 ITYLSFLCSRLLDLRQETRAARLIQAAWRKYRMKRE-LKLSQERDRAARIIQKSAMNFLARRRILRKEKAAIFIQKHWRGYLARMTL-----------FNLKKAKLEEARNKSATVIQAYWRRYSARRRYLQLRHCVIFVQARIRMVKSVAAYKQIVGATVTIQRHLRAAKLAK-IDRQRYQILKSS-ALTIQSAFRRWRKYKIQQKIKAALVIQSYFRKWQSSKLAKRKR-AALVIQSWYRMHRDLKQYLHVKQSVIKIQAWYRCQLARHVYQKNRAKIVTIQQYYRAYKLAK--GERECYLQKRAAVIVLQAAFRGMKARELYRQ--------ARAACVIQSLWRMKREKQRFLQLKKSVTMLQSHVRRYQ 1511
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1131278359|ref|XP_019776077.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein isoform X2 [Tursiops truncatus]) HSP 1 Score: 247.284 bits (630), Expect = 1.859e-63 Identity = 285/1081 (26.36%), Postives = 510/1081 (47.18%), Query Frame = 0
Query: 33 KINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLI--QSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ-------AFLRIMADAQEELRQYS----------ATL-IQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWS-----------------------AQKRFASMKWAATIIQRSWRHYRFVQHLHER-------IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRM---HKARRHYRHLTHLAASAEM-------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALLW-LLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMER--GRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
++ A ++QS KM ++R++ L AL+ + A+ I Q+ + ++ R+Q + A+V LQSHFR K R +L + +A VI +++ ++ +N+R + + R+ +Q ++ ++ RQ A L+I Q R YS +TL IQ +R+H R FL R + + +QS +R W AQK F +K AA++IQ QHL R +++ L +A +QS WR +RR Q + +H A LIQ+ +R+++Q K +K M+ +A ++Q + + R+ + K + +LQ ++R + + + H H++A IQ+ +R +Q ++ Y + + + IQ++YR ++A + ++ +L AA IQ+ +R VRR+ Q + + AA +I++ ++ Q+R + A V IQ +R RH+A+ + E + AA IQ+ +R W R+ Y+ + ++ ++Q R + RR + R+S +IQR WR + EQ R Q A IQ+ +R R+ F Q +++AL ++ Y I++ +R K++ L+++ + LQAL + + ++R++ R R+ IQRA+R HR +++ + Q SAI IQ +R HK + A+ A + IQ++++ +++RKK ++ VT IQ +RGY R K+DC KI+ +RQ++ N E+ KL +RTALAL L + ++ +L LK L+V T S+ CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +Y+ DKS I+TKT LL LL +NR + + ++ +K H ER +++ + SF P + +L P W +R D + +P A +MV++ L +
Sbjct: 829 RLKNAAVKLQSIVKMKQTRKQYLHLRAAALKREERMRASCIKLQAFVRGYLVRKQVRLQRKAAVSLQSHFRMRKMRLYYLKIYKATVVIQSYYRA--YKAQVNQRKNFLQVKRAVICLQATYRGYKVRQLIKQQSTAALKI----QTAFRGYSKRMKYRSVLQSTLKIQRWYRTHKTASDIRTQFLKTRAAVISLQSAYRGWKVRKQIRREHQAAVKIQSAFRMAKAQKEFGLVKTAASVIQ---------QHLRARAAGRRQRMEYTALRLAAVMLQSTWRGRAARR---------QVQKQHKCAVLIQSCYRMYVQRKKWKIMKKAACLIQMYYRAYSTGRKQHHLYLKTKAAVVILQSAYRGMRVRKKIKEH------HKAAAAIQSSYRAYQTKKKYATYRASAVIIQRWYRD--IKIADRQRKEYLTLKKAAVKIQAVYRGVTVRRQTQHL----HAAATLIKAVFKMQQSRRRYHQMRTAAVIIQTAWR------------------RHKAR-KYLREVK--AACKIQAWYRCWKARKEYLAVLRAVRIIQGCFRTKLQRRRFLNVRASTIIIQRKWRAVLSGRTAHEQFLTTKRFQAACLIQANFRGYKGRQVFLQQKSAAL-TIQRY----IRARKTEKSERRKYVELKKSTVVLQALVRGWLVRKRILEQRAKIRLLHFTAAAFYHLSALRIQRAYRLHRALKNADDKQ-----VNSAIRIQRWFRARLQHKRFLQKHRFMKIQNEAQERISQQNRAASVIQKAVRRFLLRKKQEKLDNRVTKIQALWRGYSWRK--KNDC------------------SKIKAIRQRLQCVNREIREENKLYHRTALALHYLLTYKYLSAILEALKHLEVVTGLSSLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIGYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYQEKPGDKVADKSRSIFTKTCCLLAVLLKRTNRASDVRSRSKVVDRIYSLYKLTAHKHKVNTERILCKQKKKSMSISFIPETPVRTRMVSRLK--PDWVLRRDNLEEIMNPLKAIQMVMDTLGI 1817 HSP 2 Score: 157.918 bits (398), Expect = 2.696e-35 Identity = 214/841 (25.45%), Postives = 388/841 (46.14%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMA--DAQEELR----------QYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHER-------IQFRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWR----RFKFVQSLAHHL-------------KWKRMHQSATRIQTQWRMWQARQSYL-----------RTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRG----KFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L+ +I IN A IQ +W+ ++++LL K LE +N+SA++IQ +W+ + R+QF LK S++LQS R A + AA I + W+ CL +K +R ++ SA IQ ++ WR R+ L+ A Q R + +A +IQS +R E + ++H+R + IQ+ FR + AQK + K + +Q+ ++ Y +L +R FR + +A QSYWRM R +L + + +QA R QL+ YK+M+ +A+V+Q + +I ++ ++ + + VLQ ++R R KF+ L + K+ R+ +A ++Q+ +M Q R+ YL R + +C+ +Q + R ++ R + +RK AA ++QS +R ++R +I +A +VIQS +R Y+ ++ + ++++R CLQ A + R + +S AA+ IQ+ +RG+++R +Y + +S++ +Q+ R +R + ++R++V +Q A+R + + K ++R HQ A KIQS +RM A++EF ++ +A +IQ H R ++ LR + LQ+ + A+R++ + A +IQ +R + + +K+K+M ++A IQ +R + R HL +A + + R M+ VRKK +A IQ YR YQ + + +
Sbjct: 420 RAARLIQTTWRKYKLKKDLKRHQKRDKAARIIQSAVINFLTKRQFKKEVNAALVIQKYWRRLLAKRKLLMLKKEKLEKVQNKSASVIQRYWRRYSTRKQFLKLKYYSIILQSRIRMIIAVASYKRYLWAAVTIQRHWRACLRRKQDQQR--YEMLRSSALIIQSAFRRWRQRKMQLQTEAAITLQRAFRERCVRKQVKEEKAAMVIQSWYRMQRELRKYIHIRSCVVIIQTRFRCFQAQKLYKRKKESILSLQKYYKAYLKGKVERTSYLQKRAAAIRLQAAFRGMKARNLRKQITAACVFQSYWRMRQDRLRFLNLKK---------NIIRLQAHIRKHQQLQKYKKMKKAALVIQIHFRAYISAKKVLASYQKTRSAVIVLQSAFRGMQARKKFIHILTSVIRIQSYYRAYVSKKKFLRLKNAAVKLQSIVKMKQTRKQYLHLRAAALKREERMRASCIKLQAFVRGYLVRKQVRLQRK----AAVSLQSHFRMRKMRLYYLKIY----KATVVIQSYYRAYKAQVNQRKNF---LQVKRAV------ICLQ-------ATYRGYKVRQLIKQQSTAALKIQTAFRGYSKRMKYRSVLQSTLKIQRWYRTHKTASDIRTQFLKTRAAVISLQSAYRGWKVRK------QIRREHQAAVKIQSAFRMAKAQKEFGLVKT---------AASVIQQHLRARAAGRRQRMEYTALRLAAVMLQSTWRGRAARRQVQKQHKCAVLIQSCYRMY------VQRKKWKIMKKAACLIQMYYRAYSTGRKQHHLYLKTKAAVVILQSAYRGMR---VRKKIKEHHKAAAAIQSSYRAYQTKKKYAT 1201 HSP 3 Score: 90.8929 bits (224), Expect = 1.078e-14 Identity = 122/465 (26.24%), Postives = 213/465 (45.81%), Query Frame = 0
Query: 326 QKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYR-----SHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQR------IIQTRNEAALVIQSAWRQYQNRLCLERRIQACVR-----------------IQRGFRKFIQR---------CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
+ R+AR++Q +WR++K + L H ++ ++A IQ+ + ++ + + NA L IQKY+R + L + K+++ +A+ IQ WRR R++ + I+Q+R + + S R + ++R +AC+R IQ FR++ QR LQR ER + +E+ AA++IQS +R + ++YI +R +++Q + R + ++ Y+R + S+ +Q+ ++ + L ++E S ++ R A ++Q+ +R AR QI A A + QS+WR R +FL L++ IRLQA H IR +LQKYK M ++A+ IQ +R + + + SA + + R MQ RKKFI I +V IQ +YR Y + F
Sbjct: 418 ETRAARLIQTTWRKYKLKKDLKRH---QKRDKAARIIQSAVINFLTKRQFKKEVNAALVIQKYWRRLLAKRKLLMLKKEKLEKVQNKSASVIQRYWRRYSTRKQFLKLKYYSIILQSRIRMIIAVASYKRYLWAAVTIQRHWRACLRRKQDQQRYEMLRSSALIIQSAFRRWRQRKMQLQTEAAITLQRAFRERCVRKQVKEEK--------AAMVIQSWYRMQRELRKYIHIRSCVVIIQTRFRCFQAQKLYKRKKESILSLQKYYKAY-LKGKVERTSYLQKRAA-AIRLQAAFRGMKARNLRKQITA----------ACVFQSYWRMRQDRLRFLNLKKNIIRLQA---------------------------H--IRKHQQLQKYKKMKKAALVIQIHFRAYISAKKVLASYQKTRSAVIVLQSAFRGMQ---ARKKFIHILTSVIRIQSYYRAYVSKKKF 827 HSP 4 Score: 69.3218 bits (168), Expect = 4.069e-8 Identity = 87/362 (24.03%), Postives = 179/362 (49.45%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSR-------------QELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRF---------------ASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRM------WMSRRSYLRFQTEAQEEL--EHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQK 327
YLTL+++ IQ +R ++ ++ + L + AT I++ +KM +SR Q RR K L+ ++A IQ+ ++ R+++ A+ A ++Q FR RRRFL ++ + +I + W+ L + +E+ + ++A IQ ++ ++GRQ FL+ A +++Y I+++ SER+ ++ L+ ST+ +Q+ R W +KR A +A IQR++R +R +++ ++ SA +IQ ++R ++ + +++ Q EAQE + ++ +A++IQ R ++ K +++ +QA +G+ R++ + K
Sbjct: 1226 YLTLKKAAVKIQAVYRGVTVRRQTQHL------HAAATLIKAVFKMQQSRRRYHQMRTAAVIIQTAWRRHKARKYLREVKAACKIQAWYRCWKARKEYLAVLRAVRIIQGCFRTKLQRRRFLNVRASTIIIQRKWRAVLSGRTAHEQFLTTKRFQAACLIQANFRGYKGRQVFLQ-QKSAALTIQRY----IRARKTEKSERRKYVELKKSTVVLQALVRGWLVRKRILEQRAKIRLLHFTAAAFYHLSALRIQRAYRLHRALKNADDK-----QVNSAIRIQRWFRARLQHKRFLQKHRFMKIQNEAQERISQQNRAASVIQKAVRRFLLRKKQEKLDNRVTKIQALWRGYSWRKKNDCSK 1571
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1348510074|ref|XP_023986460.1| (abnormal spindle-like microcephaly-associated protein isoform X2 [Physeter catodon]) HSP 1 Score: 247.284 bits (630), Expect = 1.865e-63 Identity = 284/1075 (26.42%), Postives = 516/1075 (48.00%), Query Frame = 0
Query: 33 KINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLI--QSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ-------AFLRIMADAQEELRQYS----------ATL-IQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWS-----------------------AQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMH-KARRHYRHLTHLAASAEM---------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALLW-LLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
++ A ++QS KM ++R + L AL+ + + A+ I Q+ + ++ R+Q + A+V LQSHFR K R +L + +A VI +++ ++ +N+R + R+ +Q ++ ++ RQ A L+I Q R YS +TL IQ +R+H R FL R + + +QS +R W AQK F +K AA++IQ+ R ER+++ L + +QS WR +RR Q + +H A LIQ+ +R+++Q K +K MR +A ++Q + + R+ + K + +LQ ++R + + + H H++A IQ+++R +Q ++ Y + A + IQ++YR ++A + ++ +L AA IQ+ +R VRR+ IQ + AA +I++ ++ Q+R + A V IQ +R RH+A+ + E + AA IQ+ +R W R+ Y+ + ++ ++Q + RR + R+S +IQR WR + EQ + RHQ A IQ+ +R R+ F Q +++AL ++ Y I++ G +R K++ L+++ + LQAL + + ++R++ R R+ IQRA+R H +++ Q SAI IQ +R + +R + + + E A + IQ+++ +++RKK + +T IQ +RGY R K+DC KI+ +RQ++ N E+ KL +RTALAL L + ++ +L LK L+V TR S+ CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +Y+ DKS I+TKT LL LL +NR + + ++ +K H H+++ +++ +++ + + SF P + +L P W +R D + +P A +MV++ L +
Sbjct: 1677 RLKNAAVKLQSIVKMKQTRTQYLHLRAAALKREEHMRASCIKLQAFVRGYLVRKQVRLQRKAAVSLQSHFRMRKIRLYYLKIYKATVVIQNYYRA--YKAQVNQRKTFLQVKRAVICLQATYRGYKVRQLIKQQSTAALKI----QTAFRGYSKRMKYQSVLQSTLKIQRWYRTHKAVSDIRTQFLETRAAVISLQSAYRGWKVRKQIRREHQAAVKIQSAFRMAKAQKEFELLKTAASVIQQRLRARA--AGRRERMEYTALRLAGVTLQSTWRGRAARR---------QIQRQHKCAVLIQSCYRMYVQRKKWKIMRKAACLIQMHYRAYSTGRKQHHLYLKVKAAVVILQSAYRGMRVRKKIKGH------HKAAAAIQSRFRAYQTKKKYATYRAAAVIIQRWYRD--TKMADRQRKEYLTLKKAAVKIQAVYRGVAVRRQ----IQHMHTAATLIKAVFKMQQSRRRYHQMRTAAVIIQTVWR------------------RHKAR-KYLREVK--AACKIQAWYRCWKARKEYLAVLRAVRIIQGCFCTKLQRRRFLNVRASTIIIQRKWRAVLSGRTAREQLLVTKRHQAACLIQANFRGYKGRQVFLQQKSAAL-TIQRY----IRARKAGKCERIKYVELKKSTVVLQALVRGWLVRKRILEQRAKIRLLHFTAAAFYHLSALRIQRAYRLHMALKNANNKQ-----VNSAICIQRWFRARLQQKRFLQKHSFIKIQNEAQERMNQQNRAASVIQKAVCRFLLRKKQEKFNNRITKIQALWRGYSWRK--KNDC------------------TKIKAIRQRLQCVNREIREENKLYHRTALALHYLLTYKYLSAILEALKHLEVVTRLSSLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIGYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYQEKPGDKVADKSRSIFTKTCCLLAVLLKRTNRASDVRSRSKVVDRIYSLYKLTAHKHKVNTERILCKQKKKSSMSISFIPETPVRTRMVSRLK--PDWVLRRDNLEEILNPLKAIQMVMDTLGI 2666 HSP 2 Score: 163.696 bits (413), Expect = 5.268e-37 Identity = 210/834 (25.18%), Postives = 391/834 (46.88%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMA--DAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHER-------IQFRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQ-----KYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCL--SERIALRHEAQERAW-----TESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRG----WIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQ--ASALEELK-----------NYSA-----ILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQ---RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
R+ +IQ +WR+Y L + L+ +I IN A IQ +W+ ++++LL K LE +N+SA++IQ +W+ + R+QF LK S++LQS R A + AA + + W+ CL +K +R ++ S IQ ++ WR R+ L+ A Q R++ +A +IQS +R E + ++H+R + IQ+ FR + AQK + K + +Q+ ++ Y +L +R FR + +A QSYWRM R +L + + +QA R Q + YK+M+ +A+V+Q + +I ++ ++ + + VLQ ++R + + H L S RIQ+ +R + +R+ +LR +NA + +Q K R+ L A ++ E + A+ I+ A+ R + R++ R+ + +AA+ +QS +R + RL + +A V IQ +R + + ++ +R + +A R + + +S AA+ IQ+ +RG+++R +Y + +S++ +Q+ R +R + +R++V +Q A+R + + K ++R HQ A KIQS +RM A++EF ++ AS +++ Y+A + +QS WRG R + R + + +Q+ + + +++ MR++A +IQ RA+ R HL Y + + + +QS +R + R+ + A A IQ + + +KK+ R A +IQ+ YR
Sbjct: 1268 RAARLIQTTWRKYKLKKDLKRHQKRDKAARIIQSAVINFLTKRRFKKEVNAALVIQKYWRRLLAKRKLLMLKKENLEKVQNKSASVIQRYWRRYSTRKQFLKLKYYSIILQSRIRMIIAVASYKRYLWAAVTVQRHWRACLRRKQDQQRYE--MLRSSTLIIQSVFRRWRQRKMQLQTEAAITLQRAFREWCVRKHVKEEKAAMVIQSWYRMQRELRKYIHIRSCVVIIQTRFRSFQAQKLYKRKKESILSLQKYYKAYLKGKVERTSYLQKRAAAIRLQAAFRGMKARNLRKQITAACVFQSYWRMRQDRLRFLNLKK---------NIIRLQAHIRKHQQSQKYKKMKKAALVIQIHFRAYISAKKVLASYQKTRSAVIVLQSAYRAMQARKKFIHIL------TSVIRIQSYYRAYVSRKKFLRLKNAAVKLQSIVKMKQTRTQYLHLRAAALKREEHMRASCIKLQAFVRGYLVRKQVRL---QRKAAVSLQSHFRMRKIRLYYLKIYKATVVIQNYYRAYKAQVNQRKTFLQVKRAVICLQATYRGYKVRQLIKQQSTAALKIQTAFRGYSKRMKYQSVLQSTLKIQRWYRTHKAVSDIRTQFLETRAAVISLQSAYRGWKVRK------QIRREHQAAVKIQSAFRMAKAQKEFELLKTAASVIQQRLRARAAGRRERMEYTALRLAGVTLQSTWRGRAARRQIQRQHKCAVLIQSCYRMYVQRKKWKIMRKAACLIQMHYRAYSTGRKQHHL-----YLKVKAAVVILQSAYRGMRVRKKIK-------GHHKAAAAIQSRFRAYQTKKKYATYRAAAVIIQRWYRD 2063 HSP 3 Score: 103.605 bits (257), Expect = 1.906e-18 Identity = 121/465 (26.02%), Postives = 226/465 (48.60%), Query Frame = 0
Query: 326 QKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR---LAFQAER--KLESLAATTIQSAWRRNQVRRERQR------IIQTRNEAALVIQSAWRQYQNRLCLERRIQACVR-----------------IQRGFRKFIQR---------CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
+ R+AR++Q +WR++K + L H ++ ++A IQ+ + ++ + + NA L IQKY+R +A+ L + E K+++ +A+ IQ WRR R++ + I+Q+R + + S R + ++R +AC+R IQ FR++ QR LQR E +H +E+ AA++IQS +R + ++YI +R +++Q + R + ++ Y+R + S+ +Q+ ++ + L ++E S ++ R A ++Q+ +R AR QI A A + QS+WR R +FL L++ IRLQA + ++ M+++A +IQ +R + I L Y+ + I +QS +R +AR+ + H+ + IQ + +V RKKF+R++ A +Q + Q RT +
Sbjct: 1266 ETRAARLIQTTWRKYKLKKDLKRH---QKRDKAARIIQSAVINFLTKRRFKKEVNAALVIQKYWRRLLAKRKLLMLKKENLEKVQNKSASVIQRYWRRYSTRKQFLKLKYYSIILQSRIRMIIAVASYKRYLWAAVTVQRHWRACLRRKQDQQRYEMLRSSTLIIQSVFRRWRQRKMQLQTEAAITLQRAFREWCVRKHVKEEK--------AAMVIQSWYRMQRELRKYIHIRSCVVIIQTRFRSFQAQKLYKRKKESILSLQKYYKAY-LKGKVERTSYLQKRAA-AIRLQAAFRGMKARNLRKQITA----------ACVFQSYWRMRQDRLRFLNLKKNIIRLQAHIRKHQQSQKYKKMKKAALVIQIHFRAY--ISAKKVLASYQKTRSAVIVLQSAYRAMQARKKFIHIL-------TSVIRIQSYYRAYVSRKKFLRLKNAAVKLQSIVKMKQTRTQY 1698 HSP 4 Score: 100.523 bits (249), Expect = 1.653e-17 Identity = 154/609 (25.29%), Postives = 284/609 (46.63%), Query Frame = 0
Query: 32 RKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQRE----QFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWR-GRQA---FLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQA------------------QVKGW---------------------------IQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAER--KLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWR 585
R+ +Q A +IQS ++M ++++E EL + +A++IQ +A ++ AL+ A V LQS +R ARR+ + A +I ++ + +R +M ++A IQ +++ + GR+ +L++ A + ++QS +R RK + IQS FR + +K++A+ + AA IIQR +R + +R ++ L ++A KIQ+ +R RR Q + H +ATLI+A +++ + Y QMR +A+++Q +++ W +QRR+F + + S ++QR WR ++ L + HQ+A IQ +R ++ RQ +L+ ++A L IQ+Y R AR A + ER +E +T + A R + R+RI++ R + L+ +A Y + +RIQR +R +AL++ ++ + AI IQ +R Q++R++ + S I +Q + + R +++R++ VIQ+A RF L+++ +E+ R+ TKIQ+LWR
Sbjct: 1879 RREHQAAVKIQSAFRMAKAQKEF--------ELLKT-AASVIQQRLRARAAGRRERMEYTALRLAGVTLQSTWRGRAARRQIQRQHKCAVLIQSCYRMYV------QRKKWKIMRKAACLIQMHYRAYSTGRKQHHLYLKVKA---------AVVILQSAYRGMRVRKKIKGHHKAAAAIQSRFRAYQTKKKYATYRAAAVIIQRWYRDTKMADR--QRKEYLTLKKAAVKIQAVYRGVAVRR---------QIQHMHTAATLIKAVFKMQQSRRRYHQMRTAAVIIQTVWRRHKARKYLREVKAACKIQAWYRCWKARKEYLAVLRAVRIIQGCFCTKLQRRRFLNVRASTIIIQRKWRAVLSGRTAREQLLVTKRHQAACLIQANFRGYKGRQVFLQQKSAALTIQRYIR---ARKAGKCERIKYVELKKSTVVLQALVRGWL--VRKRILEQRAKIRLLHFTAAAFYH---------LSALRIQRAYR-------------LHMALKNANNKQVNS------AICIQRWFRARLQQKRFLQ-KHSFIKIQNEAQ----ERMNQQNRAA-SVIQKAVCRF-LLRKKQEKFNNRI-----TKIQALWR 2407 HSP 5 Score: 70.0922 bits (170), Expect = 2.946e-8 Identity = 73/275 (26.55%), Postives = 133/275 (48.36%), Query Frame = 0
Query: 501 AAILIQSHWRGWTQRQ---RYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKR----LEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQAS------------ALEELKNY--SAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
AA LIQ+ WR + ++ R+ K++ ++Q V ++ +R +++ ++ VIQ+ WRR L KR L++++ +++++ A+ IQ WR R++F +++ A+ K Y +A+ +Q HWR C++R + Q+R +R S IIQ +RR R +K ++ T++AIT+Q +R R+H + E A IQ +M +K+I IR V +IQ +R +Q + +K
Sbjct: 1269 AARLIQTTWRKYKLKKDLKRHQKRDKAARIIQSAVINFLTKRRFKKEVNAALVIQKYWRRL-LAKRKLLMLKKENLEKVQNKSASVIQRYWRRYSTRKQFLKLKYYSIILQSRIRMIIAVASYKRYLWAAVTVQRHWRACLRRKQ-------------------DQQRYEMLRSSTLIIQSVFRRWRQ-------RKMQLQTEAAITLQRAFREWCVRKHVKE--------EKAAMVIQSWYRMQRELRKYIHIRSCVVIIQTRFRSFQAQKLYK 1508
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|1126177728|ref|XP_019621187.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein homolog [Branchiostoma belcheri]) HSP 1 Score: 247.284 bits (630), Expect = 2.082e-63 Identity = 302/1076 (28.07%), Postives = 512/1076 (47.58%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALE--------------LKRNQSATLIQSHWKAHIQREQFCA----LKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQY-SATL-IQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKF-IQRCCLQRCLSERIALRH-EAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEE--------QSEMRL----RHQWATK-----IQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY----RHLTHLAASAE-------MAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLLASSNRV-KKILTLPLNAKKLLESHKHYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLC----PPWQIREDVIRHHKDPFLASEMVLNKLALK 1018
R+V IQ +WR+Y + E + + ++Q+ + R+ L R+ K A LK+++ A ++Q H +AH+ R+Q A ++ A++ LQ+ R RRR M+ AA I W+G H + + + +AT IQ ++K ++ +M + Q R SAT+ +Q+ R RK S IQ+ R W+A++++ + AA ++Q R + +H R Q + ++ ++Q+ R + RRS R +H SAT IQ R W + + + R +AI+LQ V+ + R+Q +Q R V + + R V+ +R H+SAT IQT R W ARQ YL+ + A + +Q + R+H+AR QA + A +Q+A R VRR RQ+ +Q A IQ+ WR +Q + + A IQ+ F+ F + + + S R A + +A R + L +A +IQ+ RGWT RQ+Y+ R+++I++Q+ VR + R+ Y+ R + +Q R F ++L + Q+ R RH +T+ +Q+ +R ARR F Q++ L++ +A++IQS +RG R +FL+ R + + L + A L +MR +QRA+RR+ + QK K ++ I IQ+ R R+H+ R + L A+ A +Q ++M++ +K+ IR R+AV +Q +RGY R K+ K+I QK+ A ATEDKKL N TA AL+ L + + ++ +L L+ L+V TR S+ CCD+++ V+++ L++ CNRS+P +II + + +NLAK P + + +ETL+ ++ IYR+K I+ +T LL L ++ K++L LP +KL ++ R M R ++R + R SP P + + P W + +D + +P A ++VL L L+
Sbjct: 1970 RAVRTIQAAWRKYHPKPAVREWT--ESVKRATIRLQAAVRGTLVRRSLQRQHKSATTIQTAVRGWTARQHYLKQHKGAIILQQHVRAHLARKQAQARYQHVRRATIRLQAAVRGMHIRRRQKQMQMAATRIQACWRG-----H-QQSVKYKAIKLAATIIQQHFKSFK-------VMQEKQHMYRSLRSATIRLQAAVRGMLLRKLLQRQHKSATTIQTAVRGWTARQQYLKQRQAAIMLQDHVRAHLARKHAQARYQH--VRRATIRLQAAVRGTLVRRSLQR---------QHKSATTIQTAVRGWTARQQFLKQRQAAIILQQHVRAHLARKQ--AQARYQHVRRATIRLQAAVRGTLVRRSLQRQHKSATTIQTAVRGWTARQQYLKQRQAAIMLQDHVRAHLARKHAQARYQHVRRATIRLQAAVRGTHVRR-RQKQMQI---ATTRIQACWRGHQQSVKYKAIKLAATIIQQHFKSFKVMQEKQHKYRSLRSATKQLQAAVRGMLVRKMLQRQHKSATIIQTAVRGWTARQQYLKQRQAAIILQQHVRAHLARKHAQARYQHVRRATIQLQAGIRGFLARQQLIKWTHASTVIQASFRCFLQRRHYLSTRAAVCRLQAGFRGWTARRTFQQVK------LQHRAAVVIQSTYRGFAAR-RFLQQWRAEQQRRLLHFSTAAYYHLAAMR-----LQRAYRRYLV------WQKAKQQLKALIIIQASIRAWLQRKHFLQLRRVVCKLQAAVRCHQKQRLTAAVVLQSYVRMYLAKKRAIRRRKAVIALQATWRGYHTRKNIKN--------------------KRIRIAHQKIMAAKRAATEDKKLCNMTATALNLLLKYKHLSTILDALRSLEVVTRLSSVCCDRLVQGG--AVQVIYTLIQSCNRSLPCQEIIKYSISILLNLAK-NPDTVAAAVVQEGGVETLVSLMAIYREKDDVIFGQTCLLLTLFCNNAAYQKEVLNLPSVTQKLQSLYRLVKR--KTSMSRSKQRTGSQEDR-RKSPT------PLVQMVHQIKPAWILGKDNMLDVPEPLQAIQLVLETLGLQ 2963 HSP 2 Score: 118.242 bits (295), Expect = 6.151e-23 Identity = 157/567 (27.69%), Postives = 256/567 (45.15%), Query Frame = 0
Query: 240 HERIQFRLLNQSATKIQSYW---------------RMWMSRRSYL--RFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQ----MRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFI---QRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQR----GKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRH----YRHL--THLAASAEMAGATI---QRSMQMWVVR-----------KKFIRIRRAVTVIQKHYRGYQV 749
HE+ FRL+NQ ++ + ++ M+ SYL R +Q+ + IQA WR + A ++ ++ + I LQA V+G + RR + R H+SAT IQT R W ARQ YL+ + +Q++ R+H+AR QA + A +Q+A R +RR RQ+ +Q AA IQ+ WR +Q + + A IQ+ F+ F ++ + R L +R +A R + L +A IQ+ RGWT RQ+Y+ R+++IM+Q VR + R+ Y+ R + +Q A R + + L+ Q H+ AT IQ+ R AR++F + + +AI++Q H R + R ++ +RR IRLQA + + +R L +SA IQ A +R Q+Y Q+AI +Q R H AR+H Y+H+ + A + G + Q+ MQ+ R K+ I+ A T+IQ+H++ ++V
Sbjct: 1914 HEKNNFRLVNQKVLELGTIPPLLCVADMSNTIPDEKVVMTAVSYLCARIINLSQKVR---AVRTIQAAWRKYHPKPAVREWTESVKRATIRLQAAVRGTLVRRSLQ-----------------------------RQHKSATTIQTAVRGWTARQHYLKQHKGAIILQQHVRAHLARKQAQARYQHVRRATIRLQAAVRGMHIRR-RQKQMQM---AATRIQACWRGHQQSVKYKAIKLAATIIQQHFKSFKVMQEKQHMYRSL-RSATIRLQAAVRGMLLRKLLQRQHKSATTIQTAVRGWTARQQYLKQRQAAIMLQDHVRAHLARKHAQARYQHVRRATIRLQAAVRGTLVRRSLQRQ------HKSATTIQTAVRGWTARQQFLK---------QRQAAIILQQHVRAHLARKQAQARYQHVRRATIRLQAAVRGTLVRRSLQRQHKSATTIQTA------VRGWTARQQYLKQRQAAIMLQDHVRAHLARKHAQARYQHVRRATIRLQAAVRGTHVRRRQKQMQIATTRIQACWRGHQQSVKYKAIKLAATIIQQHFKSFKV 2422 The following BLAST results are available for this feature:
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 4
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 22
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BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold1923_size24897:88..6266+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold1923_size24897-snap-gene-0.7 ID=maker-scaffold1923_size24897-snap-gene-0.7|Name=abnormal spindle-like microcephaly-associated protein homolog|organism=Tigriopus kingsejongensis|type=gene|length=6179bp|location=Sequence derived from alignment at scaffold1923_size24897:88..6266+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'abnormal spindle-like microcephaly-associated protein homolog' has the following synonyms
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