abnormal spindle-like microcephaly-associated protein homolog, maker-scaffold1923_size24897-snap-gene-0.7 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000008050 (supercontig:LSalAtl2s:LSalAtl2s479:220317:222350:-1 gene:EMLSAG00000008050 transcript:EMLSAT00000008050 description:"maker-LSalAtl2s479-snap-gene-2.31") HSP 1 Score: 156.377 bits (394), Expect = 6.114e-41 Identity = 131/485 (27.01%), Postives = 231/485 (47.63%), Query Frame = 0
Query: 482 RIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLR---KSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFA--QIQASALEELKNYSAILIQSHWRGCVQRGKFLRLR---RTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSEND-RCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLL----ASSNRVKKILTLPLNAKKLLESHKHYHRLH 953
R + E + R +S ++++IQ + R + Q ++ + LR + +MVQ VR ++ +++++R +S +++ + + IQS R A+++F +IQ KN S+++IQS RG +Q+ KF ++ R +++Q++ RR ++M++ ++ V+ Q +I H++ +A IQR+ + W+ RKKF + R V VIQ +RG++ R + N LS EVR ++ AN+ ATE+ KL NR + L LY + +A L+ I+ DLD +TR+S CCDQ++ D + V +LL+L+ RCN+S+PH+++IS +LD INL +YE +R+ + + +T +E L + V I+ K + L++L VKK T + L+E + H LH
Sbjct: 8 RFLAKQEFKRRKILMKKSKSSVVIQFYSRCYLQMEKRLKLRTELRQIVMVQSVVRRYLAKQEFKRRKSQMQMTKSS-----------------------VVIQSYVR---AKQKFKRRKIQME-----KNKSSVVIQSCVRGYLQKKKFKLMKDEIRKVVKVQSMV------RRFLAMKKKQKL---------------------VIGQGSI-------------HFKKQFIFKDDNNLAAICIQRNYRAWIYRKKFKKTIRCVIVIQSMWRGFRTRKSL---------------ICNTRLS----EVRARLVCANKEATENNKLCNRVSYVLYHLYNIKSLAVLIKIVNDLDASTRYSELCCDQMLENGDKKPVIVLLDLILRCNKSVPHIEVISGVLDTLINLVRYERTRL-YISGLRETYKTCLETLQRFEKSHVIIFAKVISFLYVLTFEKGGVEGVKKHFTKKIK-DYLMEYERKKHLLH 400
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000000998 (supercontig:LSalAtl2s:LSalAtl2s116:2039559:2041029:1 gene:EMLSAG00000000998 transcript:EMLSAT00000000998 description:"maker-LSalAtl2s116-augustus-gene-20.15") HSP 1 Score: 120.553 bits (301), Expect = 5.030e-30 Identity = 81/261 (31.03%), Postives = 141/261 (54.02%), Query Frame = 0
Query: 777 KIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSEND-RCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLL----ASSNRVKKILTLPLNAKKLLESHKHYHRLH----NKQMERGRRRNNYLPNS----FRPSPAQAKPKMPKLSLCPPWQIRED-----VIRHHKDPFLASEMVLNKLALKP 1019
++ EVR ++ N+ ATE+ KL NR + L LY + +A L+ I+ DLD +TR+S CCDQ++ D + V +LL+L+ RCN+S+PH+++IS +LD INL +YE +R+ + + +T +E L + V I+ K + L++L A +KK + + L+E + H LH + +G+RR + P S + A+AK K L + ++++D +++ K+ FL ++ L K+ P
Sbjct: 17 RLXEVRARLVCVNKEATENNKLCNRVSYVLCHLYNIKSLAVLIKIVNDLDASTRYSEFCCDQMLENGDKKPVIVLLDLILRCNKSVPHIEVISGVLDTLINLVRYERTRL-YISGLKETYKTCLETLQRFEKSHVIIFAKVISFLYILTFEKAGVEGIKKQFSKKVK-DYLMEYERKKHLLHKSVSKSKNVKGKRRIPHFPESHNCAISATIAEAKRKSDGLQIFLDKKMKKDRSQSRCLKYTKERFLWTQSRLCKVLEMP 275
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000003057 (supercontig:LSalAtl2s:LSalAtl2s172:803529:807762:-1 gene:EMLSAG00000003057 transcript:EMLSAT00000003057 description:"augustus_masked-LSalAtl2s172-processed-gene-7.0") HSP 1 Score: 73.559 bits (179), Expect = 2.222e-13 Identity = 122/502 (24.30%), Postives = 219/502 (43.63%), Query Frame = 0
Query: 248 LNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQ----------SYLRTQN---ACLAIQKYYRSHVARLAF-QAERKLESLA-------ATTIQSAWRRNQVRRERQRIIQTRNE-----------AALVIQSAWRQYQNRLCLERR-----IQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRK----SSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRG---KFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYR 701
L ++A KIQS +R + +R+ + E+ +L K++ +A+ +Q+ +G F+++K +A+ + +L K + +A +IQ+ +R +++R+ L +N A + IQ + AR QA+ L L+ A IQS +R Q R+ T NE AAL IQS +R ++ R ++ + + + +RIQ FR + R ++ L + +R +AI IQSH++G+ R+ I K ++I++Q +R + VR+ D +R +V +IQ R + KRL+E ++ A IQS ++ R +R+ A I+ E +AI IQ ++G R + L I++Q+ ++ ++ L +++A IQR +R R ++ T+SAI IQ +R KAR+ R
Sbjct: 15 LAEAAVKIQSVFRGFQTRKDITKEDVESLPDLND-------------------KELAEAAVKIQSVFRG------FQTRKSAAKEDEEPL----------PNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLNDENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRK-----YITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVGSAIRIQTVFRGYKARKKIRNNL---LLVR--------------SAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKE---IKKTTSAALMIQSCFK-RFKKRKLALIEKQKEEN----AAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQKAALQIQRVYRCFRTKESTEDI------TRSAILIQGAFRGFKARKKAR 445 HSP 2 Score: 70.0922 bits (170), Expect = 2.781e-12 Identity = 113/487 (23.20%), Postives = 219/487 (44.97%), Query Frame = 0
Query: 31 ERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRN----QSATLIQSHWKAHIQREQFC-------------ALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI---MADAQEELRQYSATLIQSQWRSHSERKAFLH----------LRHSTLRIQSEFRKWSAQKRFASMKWAATI-----IQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQA---QWRVWIQLKAYKQMRCSAIVL-QAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYL----RTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR 472
++++ + A +IQS ++ ++R+++ + +L + ++A IQS ++ R+ L A+V +QS FR K+R+R I+ L ++L+E +A IQ + + R+ + + D ++ SA IQS +R RK + L + L+IQS FR + +K+ K A + IQ +R Y+ + + + LL +SA KIQS+++ + R++ + E ++ + +A LIQ+ ++V LK Q R A++L Q+ ++G+ +S +R K + K+ +A IQ+ ++ ++ R+ L + +NA + IQK Y+ R + ++++E+L A IQS++R + R+E ++ +AAL IQ +R ++ + E ++ + IQ FR F R
Sbjct: 12 DKELAEAAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRV-------NNINDHSLPDLNDENLSE---------AAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRKYITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVGSAIRIQTVFRGYKARKKIRNNL---LLVRSAIKIQSHYKGYKVRKALI---NENKKRMR--AAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGY-----------------KSRKRLKEI---------KKTTSAALMIQSCFKRFKKRKLALIEKQKEENAAIQIQKVYKGFKTR---KDKKEMETLMFAVIKIQSSYRSYKRRKE----LEKDQKAALQIQRVYRCFRTKESTEDITRSAILIQGAFRGFKAR 441 HSP 3 Score: 69.3218 bits (168), Expect = 4.547e-12 Identity = 105/467 (22.48%), Postives = 202/467 (43.25%), Query Frame = 0
Query: 144 SATKIQGYWKMWRGRQAFLR----IMADAQEELRQYSATLIQSQWRSHSERKAFL-------------HLRHSTLRIQSEFRKWSAQKRF-------------ASMKWAATIIQRSWRHYRFVQHLHE------RIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQ---SYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCL---ERRIQACVRIQRGFRKFIQR--CCLQRCLSERIALRHEA--------QERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRF 558
+A KIQ ++ ++ R+ + + D ++ +A IQS +R RK+ L + ++IQS FR + ++KR ++ AA +IQ + + + L++ + + L +SA +IQS +R + +R+ Y+ EL + K++ +A+ +Q+ +G+ R++ + +K + V SA RIQT +R ++AR+ + L + + IQ +Y+ + R A E K AA IQS R +VR+ + Q R A ++IQS R Y++R L ++ A + IQ F++F +R +++ E A++ + +++ E+ A I IQS +R + +R+ +K+++ +Q+ R + + E S +IQ A+R F
Sbjct: 18 AAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLNDENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRK-YI-----TNNELPNLDD----------------KKLAMAALKIQSVFRGFRMRKKIDDKKTATLV------------------------GSAIRIQTVFRGYKARKKIRNNLLLVRSAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKEIKKTTSAALMIQSCFKRFKKRKLALIEKQKEENAAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQKAALQIQRVYRCFRTKESTEDITRSAILIQGAFRGF 438 HSP 4 Score: 60.8474 bits (146), Expect = 1.963e-9 Identity = 103/415 (24.82%), Postives = 174/415 (41.93%), Query Frame = 0
Query: 408 AATTIQSAWR----RNQVRRERQRIIQTRN-----EAALVIQSAWRQYQNRLCLERRIQ-------------ACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYI------------GLRKSSIMVQKQVRGWIVRR----------DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNY-----SAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACI-AQRRLVSMRESAR-------IIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRR---AVTVIQKHYRGYQVRTAFKSDCK 758
AA IQS +R R + +E + N EAA+ IQS +R +Q R + + A V+IQ FR F R + + ++ E+ S AAI+IQS + G+ R+ L +S+I +Q RG+ R+ D ++ + IQ +R F + K+++++ L A +IQ+++R AR++ ++N SAI IQSH++G R + + +R L ++CI A + +++E + +IQ R ++ + L E++K T +A+ IQS ++ K R+ LA E A IQ+ + + RK + AV IQ YR Y+ R + D K
Sbjct: 18 AAVKIQSVFRGFQTRKDITKEDVESLPDLNDKELAEAAVKIQSVFRGFQTRKSAAKEDEEPLPNLNDKGLADAAVKIQSVFRGFKSRKRVNNINDHSLPDLND-------ENLSEAAIMIQSVFHGFHARKDLNQADESLPDLSDKDLAESAIRIQSVFRGFQTRKYITNNELPNLDDKKLAMAALKIQSVFRGFRMRKKIDDKKTATLVG-SAIRIQTVFRGYKARKK-----------IRNNLLLVRSAIKIQSHYKGYKVRKALINENKKRMRAAILIQSCIRAYKVRKALKEDNQRRIRAVILIQSCIRGYKSRKRLKEIKK---TTSAALMIQSCFKRFKKRK-------LALIEKQKEENAAIQIQKVYKGFKTRKDKKEMETLMFAVIKIQSSYRSYKRRKELEKDQK 403
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Match: EMLSAG00000011962 (supercontig:LSalAtl2s:LSalAtl2s84:1272304:1281371:-1 gene:EMLSAG00000011962 transcript:EMLSAT00000011962 description:"maker-LSalAtl2s84-snap-gene-12.11") HSP 1 Score: 63.1586 bits (152), Expect = 3.868e-10 Identity = 49/145 (33.79%), Postives = 76/145 (52.41%), Query Frame = 0
Query: 512 WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREF-----------AQIQA-----SALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAK 640
+ ++ R L IM+QK V+GW+ R+ Y R ++ R++QR R F +R+ MR R Q A KIQ+ R + R+ F A+I+ + +E LK AILIQ H RG +QR K+L+ R I +Q++ +
Sbjct: 736 YMEKLRSEKLMACGIMIQKHVKGWLARKKYIRLLTATRLLQRLSRGFIARRRI---FHMR-RLQAAVKIQAFIRGXLRRKSFNRTKELTIGLQARIRGYNARKNHIEFLKEKKAILIQKHVRGFLQRSKYLKNRNQVILVQSIVR 876
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391789|sp|P62292.1|ASPM_MACMU (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 242.662 bits (618), Expect = 2.531e-64 Identity = 298/1227 (24.29%), Postives = 555/1227 (45.23%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY------RHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ +SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A IQ + R R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM+ Y + Q + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F +K + TIQ+A+R +VR ++ +I+ AA+V QSA W + + C + + +A V IQ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ + R+ IQRA++ + +++ + S I IQ +R ++ + + + H + A + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYRANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITIQSSYCTIR------RLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQK----SVRTIQAAFRGMKVR-QKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAVLLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3477 HSP 2 Score: 159.844 bits (403), Expect = 3.304e-38 Identity = 213/838 (25.42%), Postives = 391/838 (46.66%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++ Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMCKAIMVIQNYYHAYKAQVNQRKNFLRVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 151.754 bits (382), Expect = 9.756e-36 Identity = 221/909 (24.31%), Postives = 409/909 (44.99%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSER---------------------------KAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAW---RRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G Q++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ K + LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q + +QR+ + Q+RSA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA TIQS++ RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R + Y++ + + ++IQ + R ++ + L+H L + + F + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYRANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITIQSSYCTIRRLMVKKK----LQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKY-------RANKKKQKALQH------NELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIV 2773 HSP 4 Score: 139.043 bits (349), Expect = 8.581e-32 Identity = 194/731 (26.54%), Postives = 340/731 (46.51%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRG----WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS A++R AA +I K+W+ L Q+ L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW +K + +K A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ +MRL+ + +QS +RMR AR+ + ++ A+ ++NY ++ QR FLR+++ LQA + ++ + +A IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1261 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLC--RQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQLQKYKKMKK----AAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRK-----------------------------QMRLQRKAVISLQSYFRMRKARQYYLKM-CKAIMVIQNY----YHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN------KRVKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFR 1918 HSP 5 Score: 125.561 bits (314), Expect = 9.490e-28 Identity = 170/653 (26.03%), Postives = 303/653 (46.40%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWR---------------RHRLIRHLAELQKYKVMTQ------SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + A++R AA IIQ+ WR R + L + ++ N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR +++ K Y+ ++ S++++Q+ + W +RR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + + Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I +Q+H R Q Q+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R AR+ + I S ++ IQS++R V + +FL L+ T I+LQ++ K +++ + +R +A IQ+ +R R I+ A ++ Y V Q + I++QS +RM KAR++Y + A IQ + RK F+R+++A T +Q YRGY+VR K
Sbjct: 1260 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKW-KRRKMQSQVKATVILQRAFREW-------HLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKLQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGM-----------------------------QARKVYIHILTSVIK---------IQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMCK-------AIMVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIK 1822
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391788|sp|P62291.1|ASPM_MACFA (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 241.891 bits (616), Expect = 3.956e-64 Identity = 297/1227 (24.21%), Postives = 555/1227 (45.23%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY------RHLTHLA----ASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ +SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A IQ ++ R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM+ Y + Q + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F +K + TIQ+A+R +VR ++ +I+ AA+V QSA W + + C + + +A V IQ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ + R+ IQRA++ + +++ + S I IQ +R ++ + + + H + A + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQK----SVRTIQAAFRGMKVR-QKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAVLLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPXTPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3474 HSP 2 Score: 159.458 bits (402), Expect = 3.821e-38 Identity = 212/838 (25.30%), Postives = 391/838 (46.66%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R Q++ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++ Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHIRKHQQVQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQXKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 155.992 bits (393), Expect = 4.981e-37 Identity = 221/906 (24.39%), Postives = 407/906 (44.92%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSER---------------------------KAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + +CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G Q++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ K + LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q +QR+ + Q+RSA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA TIQS++RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R + Y++ + + ++IQ + R ++ + L+H L + + F + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQXKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHXXHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVXVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITIQSSYRRLMVKKK----LQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKY-------RANKKKQKALQH------NELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIV 2770 HSP 4 Score: 131.339 bits (329), Expect = 1.676e-29 Identity = 205/798 (25.69%), Postives = 363/798 (45.49%), Query Frame = 0
Query: 21 LVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQK---HLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRG----WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATK-------IQSLWRMRMA----RREFAQIQASA--------------LEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKA--CIAQRRLVSMRESARIIQ-----RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKK----FIRIRRAVTVIQKHYRGYQVR 750
L RL +L RK + A IQ+ W+ + KL +LKR+Q +R++ A+ ++QS A++R AA +I K+W+ L Q+ L + + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW +K + +K A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ R +V +Q +R MR Q+ K IQ+ + A R+ F +++ +A L + ++ +A+ IQS +RG +R K+ + ++ I++Q +A + R ++ A ++ R W+ + IR Q+A+ IQS +RM KA++ +R + A IQ++ + W +K +I +R AV ++Q ++G +R
Sbjct: 1256 LCARLLDL---RKEIRAARLIQTTWR----------KYKLKTDLKRHQ-------------ERDK------AARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNL--CRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQVQKYKKMKK----AAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFR-------------MRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRKQIRR---------EHQAALKIQSAFRMAKAQKQFRLF-------KTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLR 1964
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391784|sp|P62287.1|ASPM_COLGU (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 238.424 bits (607), Expect = 5.968e-63 Identity = 296/1228 (24.10%), Postives = 553/1228 (45.03%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRM-----------WMSR--RSYLRFQTEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +++ E+ ++ AT IQ+ ++M R R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH ++H L + ++A +Q ++ R+M + + Q +A LIQ+ +R H F + +++ IQ +R + A QK +W +A +IQ +++ + QHL E+ +++A IQS +RM W ++ + R + Q+ L+H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K +R MH++AT IQ+ +RM +A+ Y + A + IQ YYR ++ R F A +K + TIQ+A+R +VR++ + I + + AA+V QSA W + C + + +A V IQ+ FR+ + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG +R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R ++ + + E G + IQ++++ +V+RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++TL+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKKMREM------HRAATFIQATFRMQRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH---KLHQFLQLRKAAITVQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQAAYKGMKARQHLREK------HKAAIIIQSTYRMHRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNMQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTVVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYIRVKTERKIFLAVQK----SVRTIQAAFRGMKVRQKLKNISEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVTIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFRRMVTRKVETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGGFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQQKKFIQKYYSIEKIEHEGQECLSQRNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCVDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 162.925 bits (411), Expect = 3.410e-39 Identity = 215/838 (25.66%), Postives = 392/838 (46.78%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S+ IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + +KF++ CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ ++ + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKFQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRS--KKIATQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQ---AAYRGYKIRQLIKQQSIAAVKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYKAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 151.369 bits (381), Expect = 1.361e-35 Identity = 222/907 (24.48%), Postives = 409/907 (45.09%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLF-----QKHLN----------------ERIHLSLMNRSATKIQGYWKM------------------------WRG---RQAFLRIMADA---QEELR-----------QYSATLIQSQWRSHSERKAF---------------------------LHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY----RFVQ--------------HLHER--IQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIA-LRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQ-SLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V I+Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G +++LN R H+ M+R+AT I+ +KM ++G R+ +L I+ Q R Q +ATLIQS +R + ++ F LRHS + IQ+ FR A++ M AAT+IQR +R RF+ HL + +QF + + KIQS +R WM R+ E+ H +AT IQA +R+ Y+ ++ +++V+Q Q + +QR+ + Q+ SA +LQ ++R K + L K MH SAT IQ+++R R+ ++ + A + +Q+ YR+ + A+ KL AA T+QS++RR V+++ +Q AA++IQ+ +R ++ + + QA + IQ+ +R + R A L+ E R W +A++IQ+ ++G RQ K++I++Q R Y++ + + ++IQ +R ++ + +E++ T +Q S M M ++ Q QA AI+IQ H + R +L LR T + +Q R+L +R A I IQ +R ++ R + M ++A IQS +RMH+A+ Y+ + + A IQ ++++ RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1944 YIELRHAVLILQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATYIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQREKYLTILKAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKK--------MREM-HRAATFIQATFRMQRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHL------KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----AKHKLHQFLQLRKAAITVQSSYRRLMVKKK----LQEMQRAAVLIQATFRMHRTYVTFQTWKQASILIQQHYRTY------------RAAKLQKENYIRQWH-----SAVVIQAAYKGMKARQHLREKHKAAIIIQSTYRMHRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKE----TCVQASFQDMNMQKQIQEQHQA----------AIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTVVRTQAVICIQSYYRGFKVRRDIQN------MHRAATLIQSFYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYIRVKTERKIFLAVQKSVRTIQAAFRGMKVRQKLKNISEEKMAAIV 2770 HSP 4 Score: 142.51 bits (358), Expect = 6.607e-33 Identity = 201/737 (27.27%), Postives = 342/737 (46.40%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQR---CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWR----GWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAIL-IQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS A++R AA +I K+W+ L Q+ L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ S+L IQS FRKW Q++ S A I+QR++R + HL +R + SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + L+ + ++ Q R AA+ IQ +R +R+ Y+ +R+S I +Q VRG++VR+ +MRL+ + +QS +RMR AR+ + LK Y AI+ IQ+++ QR KFLR+++ LQA + R+L+ + A + IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1261 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWK-QRKMQSQVKATVILQRAFREW----HLRKRAK---EENSAIVIQSWYRMHKELRKYIYIRS---------CVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLC--RQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHIRKHQQLQKYKKMKK----AAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIATQKREEYMQMRESCIKLQAFVRGYLVRK-----------------------------QMRLQRKAVISLQSYFRMRKARQYY----------LKMYKAIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQAAYRG-YKIRQLIKQQSIAAVKIQSAFRGYN------KRVKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFR 1918 HSP 5 Score: 122.094 bits (305), Expect = 1.113e-26 Identity = 176/642 (27.41%), Postives = 307/642 (47.82%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW------ATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + A++R AA IIQ+ WR R + L + ++ N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR +++ K Y+ ++ S++++Q+ + W QR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + + Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I Q+H R Q Q+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS + R ++L LR + +Q +K Q+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM KAR++Y + A IQ + RKKF+R+++A T +Q YRGY++R K
Sbjct: 1260 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKQRK-MQSQVKATVILQRAFREW-------HLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKFQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYIHILTSVIKIQSYYRAYVSKKEFL--------SLKN-ATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIATQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKARQYYLKMYK-------AIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQAAYRGYKIRQLIK 1822 HSP 6 Score: 94.7449 bits (234), Expect = 3.236e-18 Identity = 146/585 (24.96%), Postives = 266/585 (45.47%), Query Frame = 0
Query: 1 MYLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAH----IQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSH----SERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAER--KLESLAATTIQSAWRRNQVRRERQRIIQTRNE--------------AALVIQSAWRQYQNRLCLERRIQACVRIQRGFR-KFIQRCCLQRCLS-ERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFA 559
++L +Q+SV IQ ++R + Q+L+ + E+ A QS +RS+ + E +++ T IQ +KA Q ++ + A+V +Q FR+ R+ T K AA I + + ++++ ++ R+A +Q Y++ W+ R+ FL L + +A ++Q+ +R+ +R+ +L +R S + IQ+ + + +++F +K + IQ WR YR ++L + ++A KIQ+++R W + + YL LKA K ++Q ++R F + + SA ++QR WR + H + H++A IQ +R ++ RQ +LR ++A L IQKY R AR A + ER +E +T I A R + R+RI++ R + AL IQ A++ Y +++ + + IQR FR + Q+ +Q+ S E+I HE QE +QR R ++ ++QK VR +++R+ E+ S + IQ WR ++
Sbjct: 2734 IFLAVQKSVRTIQAAFRGMKVRQKLKNISEEK---MAAIVNQSALCCYRSKTQ--------YEAVQSEGVT-IQEWYKASGLACSQEAEYHSQSRAAVTIQKAFRRM-VTRKVETQKCAALRIQFFLQMAVYRRRFVQQ------KRAAITLQHYFRTWQTRKQFL---------LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCK-------VKAACKIQAWYRCWRAHKEYLAI-------------------------LKAVK-------IIQGGFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIR---AREAGKRERIKYIEFKKSTVILQALVRGWL--VRKRILEQRTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQQKKFIQKYYSIEKI--EHEGQE-------------------CLSQRNR------AASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYS 3219
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391780|sp|P62283.1|ASPM_AOTVO (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 237.654 bits (605), Expect = 9.569e-63 Identity = 298/1223 (24.37%), Postives = 555/1223 (45.38%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHC----SATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRL-------------------CL--------ERRIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHKHY---HRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L LQ + IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ ++++++QS FR RRRF+++K+AA I + ++ + KH ++H L + ++A IQ ++ R+M + + +A LIQ+ +R H F +H+++ IQ +R + A Q+ + +W +A IIQ ++R + Q L E+ +++A IQS +RM+ Y + Q + + L+H + T +QA ++ + +K ++ ++I++Q K + ++ + + +QR +R+ V QS K +R MH +ATRIQ+ +RM +A Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + Q + AA+V QSA Y+++ CL + +A V IQ+ FR+ I R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q +++G+I +R +++ R+S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR L+++ + LQAL + + ++R++ R R++ +A R R + L+K S I IQ +R ++ + H E G + IQ++++ +++R+K + + Q +RGY R +DC KI+ +R + + N E+ KL RTALAL L + ++ +L +K L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +YR DKS I+TKT LL LL ++NR + + ++ +K H+++ +++ +++++ + F P + +L P W +R D + +P A +M+++ L +
Sbjct: 2304 FLRLQNAAIKIQSSYRRWMIRKKIREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKH---KLHQFLQLRKAAITIQSSYR---------RLMVKKKLQEMHRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSAVIIQAAYRGMKARQLLREK------HKAAIIIQSTYRMYRQCCLYQKLQWATKIIQEKYRANKKKHKALQHNELKKAETCLQASFQD-MNIKLIQEQDQTSIIIQKHCKAFKIKKHYLHLRAPVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHLAATRIQSFYRMHRATVDYQTKKTAVVLIQNYYRLYVRVKTERKSFLAVQK----SVRTIQAAFRGMKVRQKLKNVSQEK-MAAIVNQSALCCYRSKAQYEAVRSEGVIIQEWYKASCLACSQEAEYHSQSRAAVTIQKAFRRMITRKVETQKCAALRIQFFLQMAVYRRRFVQQKRAAVTLQHYFRMWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLRIRSSVIIIQARIKGFIQKRKFQKIRNSTIKIQAMWRRYRAKKSLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNLRASAIIIQRKWRAILSAKIAHEHFLMIQRHRAACLIQAHFRGYKGRQVFLRQKSAALNIQKYIRAREAGRRERIKYIELKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLKALRIQRAYKLYLALKKANKQINSVICIQRWFRARLQQKRFIQKCHSIKKIEHEGQERLSQQNRAASVIQKAVRHFLLRRKQEKFTSGIIKFQALWRGYSWRK--NNDCT------------------KIKAIRLSLQVVNREIREENKLYRRTALALHYLLTYKHLSAILEAVKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYREKPGNKVADKSGSIFTKTCCLLATLLKTTNRASDVRSRSKVVDRIYSLYKLTACKHKVNTERLLYKQKKDSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNLEEIINPLQAIQMLMDTLGI 3471 HSP 2 Score: 162.155 bits (409), Expect = 5.653e-39 Identity = 218/840 (25.95%), Postives = 392/840 (46.67%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
R+ +IQ +WR+Y L + L + L +K+N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK SV+LQS R A + AA I + W+ L +K +R ++ S+ IQ ++ W+ R+ L++ A Q R++ SA +IQS +R H + + ++++R + IQ FR + AQK + K + IQ+ +R Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+ +Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R+ YL + L IQ+ YRS +LA Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + +R + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +IQ H R G QR +++ LR + + LQ++ K +R+L + A IIQ R H + +K+K+M ++ + IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + +
Sbjct: 1264 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLTKQRLRKKLN-AALVIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSVILQSRIRMIIAVTCYKRYLWAAVTIQRHWRAYLRRKQDQQR--YEMLKSSSLIIQAMFRRWKRRKMQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLQKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYMKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRKIRAACVIQSYWRMRQDRVRFLNLKKIIIK---------LQAHVRKHQQLQKYKKMKKAAVTIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATVKLQSIVKMKQTRKQYLHLRATVLFIQRCYRS--KKLAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAAVKIQSAFRGYRKRVKYQSVLQSIIKIQRWYRAYKTLSDIRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAAMKIQSAFRMAKAQKQFRLFKTAAL---------VIQQHLRAWTAGRKQRMEYIELRHSVLMLQSMWKGKTLRRQLQRQHKCAVIIQSYDRMH------VQQKKWKIMKKAVLLIQKYYRAYSIGREQHHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKY 2059 HSP 3 Score: 141.354 bits (355), Expect = 1.644e-32 Identity = 202/813 (24.85%), Postives = 388/813 (47.72%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSL-VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKA----RRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR-------QAFLRI---------MADAQEELRQYSATLI--QSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQ---RSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGW-IQRRQ---FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRS-HVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKF----IQRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVR----RDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKA----RRHY--------------------RHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
YL L+ +V IQR +R L Q+ EE + ++ + ++Q+F + + R+++ + K + L QS+++ R+ + + A +++Q+++ KA R+ FL +K+AA + ++G ++ + ++ + +A KIQ ++ +R R Q+ ++I ++D + + A +I QS +R RK + ++IQS FR AQK+F K AA +IQ R+W R +R+++ L S +QS W+ RR Q + +H A +IQ+ R+ +Q K +K M+ + +++Q + + I R Q + K + LQ ++R K + + K +++A IQ+++R ++ ++ Y + + + IQ++YR + ++ L+ A IQ+ +R +VRR IQ + AA I++ ++ +Q+R+ +A + IQ +R + +QR + L L +A R R+L AA LIQS++R + Q+ + L+K + VQ++ R R + Y + R SV IQ A+ + ++ + ++ H AT IQ +R M RR F ++ +A+ + Y A L H +FLRL+ I++Q+ + + ++++ M +A IQ +R HR+ H+ +Y+ + Q+++ IQ ++ ++A R+HY RHL + +SA + IQ + +VR++FI +++A IQ+ YR
Sbjct: 1694 YLHLRATVLFIQRCYRSKKLAAQKREEYM---QMRESCIKLQAFVRGYLVRKQMRLQRKAVISL---------QSYFRMRKARQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQ------SIAAVKIQSAFRGYRKRVKYQSVLQSIIKIQRWYRAYKTLSDIRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAAMKIQSAFRMAKAQKQFRLFKTAALVIQQHLRAWTAGR-----KQRMEYIELRHSVLMLQSMWKGKTLRR---------QLQRQHKCAVIIQSYDRMHVQQKKWKIMKKAVLLIQKYYRAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRI------KDCNKAAITIQSKYRAYKTKKKYAACRASAIIIQRWYRGIKITNHQYKEYLNLKK-TAIKIQAVYRGIRVRRH----IQHMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQRENYLKILKAVNVL--QANFRGVRVRRTLRKLQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAVKERNIQFQRYNKLRHSVIHIQ------AIFRGMKARRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWVQRKYRAHLCTKH------HLQFLRLQNAAIKIQSSYRRWMIRKKIREMHRAATFIQATFRMHRV--HM----RYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAIL----IQSRFRSLLVRRRFISLKKAAIFIQRKYRA 2439 HSP 4 Score: 137.117 bits (344), Expect = 2.754e-31 Identity = 208/873 (23.83%), Postives = 399/873 (45.70%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE---------LLRRLKLALELKRNQ---------SATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL----------AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEE--------QSEMRL--------RHQWATK-IQSLWRMRMARREFAQ----------IQAS------ALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ SV ++Q W+ +L ++L+ + ++CA IQS+ +MH +++ L+++ A + R Q + +QS ++ R++ A++ +QS +R K ++++ + +A +I +W++G H + +L+L ++A KIQ ++ R R+ F++ M + +Y + +IQ ++R++ + R+ +L + + +Q+ FR ++ ++ AAT+IQ ++R YR ++ F L + +Q +R R Q + +L H S IQA +R + K M +A ++Q + + + RR+F S K++A +QR +R + HHL++ R+ +A +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + + IQ FR FIQR C + L + + LR A + R + AA+LIQ+ +R + + +SI++Q+ R + + R +Y + S +IQ A+R + L E QS R+ + QWATK IQ +R + + Q +QAS L + ++ ++I+IQ H + + +L LR + +Q R+L ++R A I IQ +R ++ R + M +A IQS +RMH+A Y+ + + A IQ +++V RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1940 YIELRHSVLMLQSMWKGKTLRRQLQ------RQHKCAVIIQSYDRMHVQQKKWKIMKKAVLLIQKYYRAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKYAACRASAIIIQRWYRGIKITNH-QYKEYLNL-KKTAIKIQAVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQRENYLKILKAVNVLQANFRGVRVRRTLRKLQIAATLIQSNYRRYR------QQTYFNKLKKITKTVQQRYRAVKERN----IQFQRYNKLRH-SVIHIQAIFRGMKARRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWVQRKYRAHLCTK---HHLQFLRLQNAAIKIQSSYRRWMIRKKIREMHRAATFIQATFRMHRVHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMKTRRHLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKHKLHQFLQLRKAAITIQSSYRRLMVKKKLQEMHRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSAVIIQAAYRGMKARQLLREKHKAAIIIQSTYRMYRQCCLYQKLQWATKIIQEKYRANKKKHKALQHNELKKAETCLQASFQDMNIKLIQEQDQTSIIIQKHCKAFKIKKHYLHLRAPVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVRRDIQN------MHLAATRIQSFYRMHRATVDYQ-------TKKTAVVLIQNYYRLYVRVKTERKSFLAVQKSVRTIQAAFRGMKVRQKLKNVSQEKMAAIV 2766 HSP 5 Score: 80.1073 bits (196), Expect = 7.637e-14 Identity = 121/447 (27.07%), Postives = 193/447 (43.18%), Query Frame = 0
Query: 358 SATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRII-----QTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQR----QRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMR--------------MARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQA-------------LAKACIAQR---------RLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
+A IQT WR ++ + R Q A + + + L Q RK + AA IQ WRR +++ + + +N+AA +IQ WR+Y R + V +Q R I C +R L W AA+ IQ HWR + +R QRY L+ SS+++Q R W RR + + +QRA+R + L KR +E+ A IQS +RM + ++ F QA L + + S + IQ ++R G ++R +L+ R I+LQA + AC+ Q R +++++ +Q R+H+ +LQKYK M ++A+TIQ+ ++ + R SA + + R MQ RK +I I +V IQ +YR Y + F S
Sbjct: 1265 AARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLTKQRLRKKLN-AALVIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSVILQSRIRMIIAVTCYKRYL--------------W------AAVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQAMFRRW-KRRKMQLQVKATITLQRAFREWHLRKRAKEEKS-------AIVIQSWYRMHKQLQKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYMKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRKIRAACVIQSYWRMRQDRVRFLNLKKIIIKLQAHVRKHQ------QLQKYKKMKKAAVTIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQ---ARKMYIHILTSVIKIQSYYRAYVSKKEFLS 1673
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391793|sp|P62296.1|ASPM_SAIBB (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.572 bits (597), Expect = 9.439e-62 Identity = 302/1231 (24.53%), Postives = 548/1231 (44.52%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRS--RQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSL-MNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQT----------------EAQEELEHC----SATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-------------------NRLCL--------ERRIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATK-IQSLWRMRMARREFAQIQASAL----------------EEL----KNYSAILIQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKL-----LESHKH---YHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L LQ + IQ S+RR+ + +++ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R + ++ ++++++QS FR RRRF+++K+AA I + ++ + KH +H L + ++A IQ ++ R+M + + +A LIQ+ +R H F +H+++ IQ +R + A Q+ + +W +A IIQ ++R + Q L E+ ++A IQS +RM+ R Y +Q + + L+H + +QA ++ K ++ +++ +Q + ++Q+ + +QR +R+ V QS K +R MH +ATRIQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + Q + AA+V SA Y+ CL + +A V IQ+ FR+ I R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R +++ ++S IQ WRR+ K L + W A K IQ + ++ R F ++ASA+ E ++ +A LIQ+H+RG R FLR L+++ + LQAL + + ++R++ R R++ +A R R + L+ SAI IQ +R ++ + + H E G + IQ++++ +++RKK + + Q +RGY R +DC KI+ +R + + N E+ KL R ALAL L + ++ +L +K L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ ++TL+E+L +YR DKS I+TKT LL LL ++NR + + ++ L ++KH RLH KQ + ++P +P + + L P W +R D + +P A +MV++ L +
Sbjct: 2299 FLRLQNAAIKIQSSYRRWVVRKKMREM------HRAATFIQATFRMHRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMETRRRLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKH---NLHQFLQLRKAAVTIQSSYR---------RLMVKKKLQEMHRAAVLIQATFRMHKTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSALIIQAAYRGMKARQLLREK------RKAAIIIQSTYRMY---RQYCLYQNLQWATKIIQEKYRANKKKHKALQHNELKKAEACVQASFQDMNIKKLIQEQHQTSLTIQKHCNAFKIKKQYLHLRAPVVSIQRRYRKLTAVHTQAVICIQSYYRGFKVRRDIQNMHLAATRIQSLYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERNSFLAVQK----SVRTIQAAFRSMKVRQKLKNLSQEK-MAAIVSPSAVYCYRIEAQSEAVGSEGVIIQEWYKTSCLAHSQEAEYHSQSRAAVTIQKAFRRMITRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAVTLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARTKGFIQKRKFQKIKNSTIKIQAVWRRYRDKKSLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGSFYXKLERTRFLNMRASAIIIQRKWRAILSAKIAHEHFLMIQRHQAACLIQAHFRGYKGRQVFLRQKSAALNIQKYIRAREAGRRERIKYIELKKSTVTLQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLKALRIQRAYKLYLALKNANKQVNSAICIQRWFRARLQQKRFIQICHSIKKIEHEGQERLSQQNRAASVIQKAVRHFLLRKKQEKFTSGIIKFQALWRGYSWRK--NNDC------------------TKIKAIRLSLQVVNREIREENKLYRRAALALHYLLTYKHLSAILEAVKHLEVVTRLSPFCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCVDTLLELLQMYREKPGNKVADKSGSIFTKTCCLLATLLKTTNRASDVRSRSKVVDRIYSLYKLTAYKHKVNTERLHYKQKKDSSTSIPFIPE----TPVRTRIVS---RLKPDWVLRRDNLEEITNPLQAIQMVMDTLGI 3467 HSP 2 Score: 163.31 bits (412), Expect = 2.377e-39 Identity = 217/839 (25.86%), Postives = 392/839 (46.72%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA--QEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
R+ +IQ +WR+Y L L+ +I IN A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S+VLQS R A + A I + W+ L +K +R + S+ IQ ++ W+ R+ L++ A Q R++ SA +IQS +R H + + ++++R + IQ FR + AQK + K + IQ+ +R Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ RM Q R+ YL + L IQ+ Y H +LA Q + + + I+ A+ R + R++ R+ + +A + +QS +R ++R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+++R +Y + +S I +Q+ R + +R + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +IQ H R G QR +++ LR + + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R +H +L A A T+Q + + VRK+ +A IQ YR Y+ + +
Sbjct: 1259 RAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQR--YEKLKSSSLIIQAMFRRWKQRKMQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLRKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRQIRAACVIQSYWRMRQDRVRFLNLKKIIIK---------LQAHVRKHQQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVRMKQTRKQYLHLRATALFIQQCY--HSKKLAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKSRQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSVAAVKIQSAFRGYSKRVKYQSVLQSIIKIQRWYRAYKTLHGIRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAAMKIQSAFRMAKAQKQFRLFKTAAL---------VIQQHLRAWTAGRKQRMEYIELRHSVLMLQSMWKGKALRRQLQRQHKCAVIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGRE-QHCLYLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKY 2054 HSP 3 Score: 132.109 bits (331), Expect = 1.114e-29 Identity = 212/893 (23.74%), Postives = 398/893 (44.57%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAH-IQREQFCA-LKT-------------------------ASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL---------------------------------AAILIQSHWRGW----TQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQ---RAWRRFALIKRLEEQSEMRLRHQWATK-IQSLWRMRMARREFAQ----------IQAS-------ALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ SV ++Q W+ +L ++L+ + ++CA IQS+++MH +Q+ + +K ++A LIQ +++A+ I REQ C LKT A++ +QS +R K ++++ + +A +I +W++ H + +L+L ++A KIQ ++ R R+ F++ M + +Y + +IQ ++R++ + R+ +L + +Q+ FR ++ ++ AAT+IQ ++R YR ++ F L + +Q +R R Q + +L H S IQA +R + K M +A ++Q + + + RR+F S K++A +QR +R + HHL++ R+ +A +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + + IQ FR FIQR C + L + + LR A + R + A+ILIQ H+R + QR+ Y S++++Q RG R+ R + +IQ R +R++ L + L QWATK IQ +R + + Q +QAS L + ++ +++ IQ H + ++L LR + +Q R+L ++ A I IQ +R ++ R + M +A IQSL+RMH+A+ Y+ + + A IQ +++V R F+ ++++V IQ +R +VR K+ + K A++
Sbjct: 1935 YIELRHSVLMLQSMWKGKALRRQLQ------RQHKCAVIIQSYYRMH-VQQKKWKIMK--------KAALLIQKYYRAYSIGREQHCLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAITIQSKYRAYKTKKKYAAYRASAIIIQRWYRSIKITNH-QYKEYLNL-KKTAIKIQAVYRGIRVRRHIQCMHRAATFIKAMFKMHQSRIRYHTMRKATIVIQVRYRAYYQGKMQREDYLKFLKAVNVLQANFRGVRVRRTLRKLQIAATVIQSNYRRYR------QQTYFNKLKKITKTVQQRYRAVKERN----IQFQRYNKLRH-SVIHIQAIFRGMKVRRHLKTMHIAATLIQRRFRTLMMRRRFLSLKKTAIWIQRKYRAHLCTK---HHLQFLRLQNAAIKIQSSYRRWVVRKKMREMHRAATFIQATFRMHRVHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMETRRRLKSMHSSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKHNLHQFLQLRKAAVTIQSSYRRLMVKKKLQEMHRAAVLIQATFRMHKTYITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSALIIQAAYRGMKARQLLREKRKAAIIIQSTYRMYRQYCLYQNL----------QWATKIIQEKYRANKKKHKALQHNELKKAEACVQASFQDMNIKKLIQEQHQTSLTIQKHCNAFKIKKQYLHLRAPVVSIQR------RYRKLTAVHTQAVICIQSYYRGFKVRRDIQN------MHLAATRIQSLYRMHRAKVDYQ-------TKKTAIVVIQNYYRLYVRVKTERNSFLAVQKSVRTIQAAFRSMKVRQKLKNLSQEKMAAIV 2762 HSP 4 Score: 120.553 bits (301), Expect = 3.810e-26 Identity = 197/736 (26.77%), Postives = 349/736 (47.42%), Query Frame = 0
Query: 62 LELKRN-QSATLIQSHW-----KAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLS---LMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSA-ILIQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI-IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L+L++ ++A LIQ+ W K ++R Q A+ ++QS ++R AA +I K+W+ L QK L + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR+ RK + L+ S+L IQ+ FR+W +K +K A +QR++R + HL +R + +SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H Q RK + + AA IQ+ ++ R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + E ++L++ A I +QS R R++Y+ LR +++ +Q+ + R +Y + R S +Q A+ R L+++ +MRL+ + +QS +RMR +R+ + LK Y A I+IQ+++ QR FL++++ LQA + R+L+ + A + IQ A+R + ++ KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + + F+
Sbjct: 1252 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQ--ERDKAARIIQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQNKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQRYEKLKSSSLIIQAMFRRWKQRKMQLQVK-ATITLQRAFREW----HLRKRAK---EEKSAIVIQSWYRMHKQLRKYVYVRS---------CVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNLH--RQIRAACVIQSYWRMRQDRVRFLNLKKIIIKLQAHVRKH------QQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSK-------KEFLSLKN-------------ATIKLQSIVRMKQTRKQYLHLRATALFIQQCYHSKKLAAQKREEYMQMRESCIKLQ-AFVRGYLVRK-----QMRLQRKAVISLQSYFRMRKSRQYY----------LKMYKAVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRG-YKVRQLIKQQSVAAVKIQSAFRGY------SKRVKYQSVLQSIIKIQRWYRAYKTLHGIR--THFLKT-KAAVISLQSAYRGWKVRKQIRREHQAAMKIQSAFRMAKAQKQFR 1909 HSP 5 Score: 118.242 bits (295), Expect = 1.754e-25 Identity = 173/658 (26.29%), Postives = 298/658 (45.29%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWR-------HYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR------RFKFVQSLAHHLKWKRMHQSATR----------IQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW------ATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER + IQS + ++R AA IIQ+ WR + ER+Q N++A+ IQ YWR + +R+ +L+ + + Q + A IQ WR ++ K Y++++ S++++QA + W QR+ + Q ++ LQR++R R K +S W RMH+ + IQ ++R +QA++ Y R + + L IQKYYR+++ + + AA +Q+A+RR + ++I AA VIQS WR Q+R+ +F+ L++ + I +Q+H R Q ++Y ++K+++++Q + +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS R R ++L LR T + +Q +K AQ+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM K+R++Y + A IQ + RK F+++++A T +Q YRGY+VR K
Sbjct: 1251 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQERDKAARI------IQSAVINFLRKQRLRKTLNAALIIQKYWRRVLAQKKLLMLKKEKLERVQ----NKAASLIQGYWRRYSTRKRFLKLKYYSIVLQSRIRMIIAVTCYKRYLWATVTIQRHWRASLRRKQDQQRYEKLKSSSLIIQAMFRRWKQRK-MQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLRKYVYVRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYRAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLHRQI-----RAACVIQSYWRMRQDRV-----------------RFLN---LKKII-----------------------IKLQAHVRKHQQLRKYKKMKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYIHILTSVIKIQSYYRAYVSKKEFL--------SLKN-ATIKLQSIVRMKQTRKQYLHLRATALFIQQCYHSKKLAAQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKSRQYYLKMYK-------AVIIIQNYYHSYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIK 1813
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391787|sp|P62290.1|ASPM_HYLLA (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.187 bits (596), Expect = 1.360e-61 Identity = 296/1222 (24.22%), Postives = 541/1222 (44.27%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQK----RFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-RKFIQRCCLQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARIIQ---------RAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ ++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A K + +A +IQ +++ + Q L E+ +++A IQS +RM+ Y + Q + Q+ +H T +QA ++ K + +AI++Q K + R+ + + + +QR R+ V QS K +R MHQ+AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ+A+R +VR++ + + + R AA+V QSA W + C + + +A V IQ+ F R ++ Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R +++ ++S IQ WRR K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R++ A R R + ++ S I IQ +R ++ + H E G + IQ+++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLXSMHFSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFRTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKQQKAFQHNELKKETCVQASFQDMNIKKQIXEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRHRKLAAVRTQAVICIQSYYRGFKVRRDIQNMHQAATLIQSFYRMHKAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEER-MAAVVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKCAALRIQFFFQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQQIKNSTIKIQAMWRRXRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRIIEQRAKIRLLHFTAAAYYHLNALRIQRXYKLYLAVKNANKQINSVICIQRWFRARLQQKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVXHFLLRKKQEKFTNGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 157.532 bits (397), Expect = 1.638e-37 Identity = 208/841 (24.73%), Postives = 383/841 (45.54%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKR-----------------------NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY-----RFVQHLHER-------IQFRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ ++ ++ A IQS ++Q L +R+ AL +++ N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y +L +R FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + I R+ ++ + + VLQ ++R + + H L ++ + + ++Q+ +M Q R YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A IQS +RM A+ +F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K M ++A+ IQ +R + R HL ++A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKR---HQETDKAARIIQSAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATIILQRAFREWHLRKQAKEENSAIVIQSWYRMHKELRKYIYIRSCXVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIRLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHVRKHQQLQKYKKMKKAAVIIQTHFRAXIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRXQYLHLRAAALFIQQCYRS--KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSMLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALTIQSAFRMAKAQXQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKTMKKAALLIQKYYRAYSIGREQ---NHLYLKTKVAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 139.043 bits (349), Expect = 7.747e-32 Identity = 198/798 (24.81%), Postives = 374/798 (46.87%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKM------WRGR-------QAFLRIMADAQEELRQY-----SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKW--KRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQR----RLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMW----VVRKKFIRIRRAVTVIQKHYRGYQVR 750
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ + QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L +R H + A IQ Y++M W+ Q + R + +E+ Y + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H++ + L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +QR ++ + ++ ++LQ S+R + ++W ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA VIQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q Y+ +R++ +L+ Q +R RH A +Q+ +R RR + ++SA LIQS +R + R +F+ L++ I +Q +A I + + + +R++A IQ ++RR + + L E+Q+ +A+ IQ+ +RMH+ +R H A IQ+ + + + R+ +IR + VIQ Y+G + R
Sbjct: 1844 YQSMLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSAYRGWKVRKQIRRE---------HQAALTIQSAFRMAKAQXQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQL-QRQH-----KCAIIIQSYYRMHVQQKKWKTMKKAALLIQKYYRAYSIGREQNHLYLKTKVAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKK--YLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQREKYLTILKAVKILQASFRGVR--------VRWTLRKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATVIQRRFRT----LMMRRRFLSLKKTAIWIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQALKQASVVIQQQ---------YQANRAA---------------KLQRQHYLRQRHS-AVILQAAFRGMKTRRHLXSM---------HFSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQR------AAVLIQATFRMHRTYITFRTWKH-------ASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKAR 2547
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391790|sp|P62293.1|ASPM_PANTR (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 234.187 bits (596), Expect = 1.373e-61 Identity = 294/1228 (23.94%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQK----RFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A K + +A +IQ +++ + Q L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F + + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRSIP M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAVVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAECHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 169.474 bits (428), Expect = 3.278e-41 Identity = 209/840 (24.88%), Postives = 392/840 (46.67%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADA------------QEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAF----QAERKLESL---------------AATTIQSAWRRNQV-RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR---------------------------------KFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R+ ++ A ++ Q SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++ ER + +A ++Q+ +R + Y + + +A +IQ+ WR+ + ++ + I LQA V+ QR++++ K++A ++Q +R + F + ++++ + +Q+ +R QAR+ Y+ + + IQ YYR++V++ F A KL+S+ AA IQ +R ++ ++R+ +Q R E+ + +Q+ R Y R + R +A + +Q FR F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEQNSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAY--LKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLYRQIR----------AACVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVL--ASYQKIRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMR-ESCIKLQAFVRGYLVRKQMRLRRKAVISLQSYFRMRKAQQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 142.124 bits (357), Expect = 8.532e-33 Identity = 210/852 (24.65%), Postives = 401/852 (47.07%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFI 787
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ ++QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +QR ++ + ++ +VLQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR+ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+L++ + Q SA+ IQ+ ++ KAR+ L A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I+E Q I
Sbjct: 1844 YQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSAYRGWKVRKQIRRE---------HQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAILIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLRRENYIRQWHSAVVIQAAYKGMKARQ-------LLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQEQHQAAII 2630
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391791|sp|P62294.1|ASPM_PONPY (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 233.032 bits (593), Expect = 3.194e-61 Identity = 296/1228 (24.10%), Postives = 548/1228 (44.63%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-RKFIQRCCLQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++M R R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL +SA IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A Q+ +W +A +IQ +++ + Q L E+ +++A IQS +RM+ Y + Q + Q+ +H T +QA ++ K + +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R +F A +K + TIQ A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F R ++ Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + +++ + S I IQ +R R+ + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2302 FLRVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQAIFRMRRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKSAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQDQHQAAIIIQKNCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLAVQK----SVRTIQPAFRGMKVRQKLKNLSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAIWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRATCLIQAHYRGYKGRQVFLRQKSAALVIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQRKRFIQKYHSIKKIEHEGQECLSQQNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PNWVLRRDNMEEITNPLQAIQMVMDTLGI 3469 HSP 2 Score: 159.844 bits (403), Expect = 2.735e-38 Identity = 214/844 (25.36%), Postives = 385/844 (45.62%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEE---------LILERKINQCATQ-----------IQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQV-RRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR---------------------------------KFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L L+ +I IN A Q +Q +W+ ++++LL K LE +N++A+LIQ +W+ + R +F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R +L + + +QA R QL+ YK+M+ +A+++Q + +I R+ ++ + + VLQ ++R + + H L S +IQ+ +R + +++ +L +NA + +Q + R + R AA IQ +R ++ ++R+ +Q R E+ + +Q+ R Y+ R + + +A + +Q FR F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q +R + + K ++R HQ A KIQS +RM AR++F + +AL +N+ A W G QR +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1262 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQSAVINFLAKQRLRKRVNAALVVQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKQAKEENSAIVIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAAGVIQSYWRMRQDRVRFLNLKK---------TIIKLQAHVRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHIL------TSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKVKQTRKQYLHLRA----AALFIQQCYRSKKIAAQKREEYMQMR-ESCIKLQAFVRGYRVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRIKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSTYRGWKVRK------QIRREHQAALKIQSAFRMAKARKQFRLFKTAALVIQQNFRA------WTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2059 HSP 3 Score: 142.51 bits (358), Expect = 6.549e-33 Identity = 209/854 (24.47%), Postives = 403/854 (47.19%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFI-QRCCLQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANEN 791
Y ++ +S+ IQR +R Y + L+ K +QS ++ + R+++ R +Q+A IQS ++ R+QF KTA++V+Q +FR A R+ ++ ++ A ++ WKG ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G +Q ++ + ++ ++LQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + + LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR++ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+LQ+ + Q SA+ IQ+ ++ KAR+ L A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I++ Q I +N
Sbjct: 1838 YQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTK--AAVISLQSTYRGWKVRKQIRRE---------HQAALKIQSAFRMAKARKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLMLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQHEKYLTILKAVKILQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAIWIQRKYRAHLYTKHHLQFLRVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQAIFRMRRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKSAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQ-------LLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQDQHQAAIIIQKN 2628 HSP 4 Score: 137.117 bits (344), Expect = 3.465e-31 Identity = 207/768 (26.95%), Postives = 356/768 (46.35%), Query Frame = 0
Query: 21 LVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQK---HLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRI------------MADAQEELRQY--SATLIQSQWRSHSERKA----FLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAIL-IQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
L RL +L RK + A IQ+ W+ + KL +LKR+Q +RE+ A+ ++QS A++R AA V+ K+W+ L Q+ L + + N++A+ IQGYW+ + R+ FL++ M A ++Y + IQ WR++ RK + L+ STL IQS FRKW +K + +K A I+QR++R + H R Q + N SA IQS++RM R Y+ ++ +IQ ++R + K YK+ + S + +Q A +KG I+R + ++ +A LQ ++RR K AH+L R ++A IQ+ WRM Q R +L + + +Q + R H ++ +K AA IQ+ +R R+ Q A +V+QSA+R Q R + + ++IQ +R ++ + E ++L++ A I +QS + R++Y+ LR +++ +Q+ R + R +Y + R S +Q A ++ + +MRL+ + +QS +RMR AR+ + LK Y AI+ IQ+++ QR FL++++ LQA + ++ + +A IQ A+R + + KY+ + QS I IQ +R +K R TH + + A ++Q + + W VRK+ R +A IQ +R + R F+
Sbjct: 1250 LCARLLDL---RKEIRAARLIQTTWR----------KYKLKTDLKRHQ-------------EREK------AARIIQSAVINFLAKQRLRKRVNAALVVQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKRRKMQSQVK-ATVILQRAFREW------HLRKQAKEEN-SAIVIQSWYRMHKELRKYIYIRS---------CVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK-----AHNL--CRQIRAAGVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQLQKYKKMKK----AAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSK-------KEFLSLKN-------------ATIKLQSIVKVKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQ------AFVRGYRVRKQMRLQRKAVISLQSYFRMRKARQYY----------LKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN------KRIKYQSVLQSIIKIQRWYRAYKTLHDTR--THFLKT-KAAVISLQSTYRGWKVRKQIRREHQAALKIQSAFRMAKARKQFR 1912
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|60391786|sp|P62289.1|ASPM_GORGO (RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog) HSP 1 Score: 233.032 bits (593), Expect = 3.224e-61 Identity = 294/1228 (23.94%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGF-----RK-------------FIQRCCLQR--CLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASAL----------------EEL----KNYSAILIQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQ+ ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L++ +HL ++A IQ ++ R+M + + Q +A LIQ+ +R H F +H+++ IQ +R + A Q+ +W +A +IQ +++ + L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MHQ+AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F RK F+Q +R +R A+ + R W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ E ++ +A LIQ+H+RG R FLR +++ + LQAL + + ++R++ R R+ IQRA++ + ++H + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+ + +I + L+R CNRS+P M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2307 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARHLLREK------HKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHQAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMEVRQKLKNVSEEK-VAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRKLETQKYAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNALRIQRAYKLYLAMKHANK------QVNSVICIQRWFRARLQEKRFIQKYHSVKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAHSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3474 HSP 2 Score: 160.614 bits (405), Expect = 1.694e-38 Identity = 208/839 (24.79%), Postives = 390/839 (46.48%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAF----QAERKLESL---------------AATTIQSAWRRNQV-RRERQRIIQTRN----------------------EAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R +F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++ ER + +A ++Q+ +R + L Q A A +IQ+ WR+ + ++ + I LQA V+ QR++++ K++A ++Q +R + F + + +++ + +Q+ +R QAR+ Y+ + + IQ YYR+HV++ F A KL+S+ AA IQ +R ++ ++R+ +Q R +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + ++++++ +Q A+R + + K ++R HQ KIQS +RM A+++F + +AL +N+ A W G QR +++ LR + LQ++ + +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1267 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLVIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKHAKEENSAIIIQSWYRMHKELQKYIYIRSCVVIIQKRFRCFQAQKLYKRKKESILTIQKYYKAY--LKGKIERTNYLQKRAAAIQLQAAFRRLKAHN--LCRQIRA--------ACVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVL--ASYQKTRSAVIVLQSAYRGMQARKMYVHILTSVIKIQSYYRAHVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAALISLQSAYRGWKVRK------QIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKA------WTAGRKQRMEYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2064 HSP 3 Score: 141.739 bits (356), Expect = 1.231e-32 Identity = 201/805 (24.97%), Postives = 380/805 (47.20%), Query Frame = 0
Query: 50 SRQELLRRLKLALELKRNQSATL-IQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRR----FLTMKRAAGVIHKWWKGCLFQKHLNE------------RIHL-----SLMNRSATKIQGYWKMWR-GR-QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVAR-LAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI----QACVRIQRGFRKFIQRCC---LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR-------------LIRH------LAELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVR-TAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFI 787
S Q R K+ +++R A L IQS ++ ++QF KTA++V+Q +F+ A R+ ++ ++ A ++ W+G ++ L R+H+ +M ++A IQ Y++ + GR Q L + A + +QS +R RK + + IQS++R + +K++A+ + +A IIQR +R + H H+ ++ L ++A KIQS +R RR H +AT I+A +++ +Y MR +AIV+Q A +G QR ++ + ++ ++LQ S+R + ++L ++M +AT IQ+ +R ++ + + + + +Q+ YR+ R + FQ KL + IQ+ +R + RR ++ + AA +IQ +R L + RR + + IQR +R + C LQ + ++ ++ R W + + AA IQ+ +R RY L+++S+++Q+Q + + R+ Y R R S ++Q A+R ++ + ++ H AT IQS +R + RR F ++ + + + Y A + H + +FL LR+ I +Q+ + + +++L M+ +A +IQ +R HR LI+ A+LQ+ + Q SA+ IQ+ ++ KAR HL A IQ + +M+ + +++ A +IQ+ YR + + AF+ + K+T + F + + K+I+E Q I
Sbjct: 1879 SLQSAYRGWKVRKQIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKAWTAGRKQRMEYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKA-------AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHK--EYLNLKKTAIKIQSVYRGIRVRRHIQHM---------HRAATFIKAVFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKTQREKYLTILKAVKILQASFRGVRVRRTL------RKMQIAATLIQSNYRRYRKQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRH----LKMMHIAATLIQRRFRT----LMMRRRFLSLKKTAILIQRKYRAHL--CTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFR------GMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKH-----KLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKAR-------HLLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQ-DMNIKKQIQEQHQAAII 2629 HSP 4 Score: 125.176 bits (313), Expect = 1.527e-27 Identity = 178/642 (27.73%), Postives = 308/642 (47.98%), Query Frame = 0
Query: 165 MADAQEELRQYSATLIQSQWRS---------HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY---RFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---QEELEHCSATL-----------IQAQWRVWIQLKA----YKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQS---AWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQ-NRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWA------TKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQAL--AKACIAQRR--LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+ D ++E+R +A LIQ+ WR H ER+ + IQ + A++R AA +IQ+ WR R + L + ++ N++A+ IQ YWR + +RR +L+ + + Q + A IQ WR +++ K Y+ ++ S +V+Q+ + W QR+ +SQ ++ +LQR++R + H K + SA IQ+ +RM + Q Y+ ++ + IQK +R A+ ++ RK ES+ TIQ A+ + ++ ER +Q R AA+ +Q+A+R+ + + LC R+I+A IQ +R +R Q+R + I +Q+H R QRQ+Y ++K+++++Q R +I R Y+++RS+V V+Q A+R M+ R + KIQS +R ++++EF LKN + I +QS + R ++L LR + +Q +K AQ+R + MRES +Q A+ R L+R LQ+ ++ I++QS +RM KAR++Y + A IQ + RK F+++++A T +Q YRGY+VR K
Sbjct: 1259 LLDLRKEIR--AARLIQTTWRKYKLKTDLKRHQEREKAARI------IQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLVIQSMFRKWKQRK-MQSQVKATVILQRAFREW-------HLRKHAKEENSAIIIQSWYRMHKELQKYIYIRSCVVIIQKRFRCFQAQKLYK--RKKESI--LTIQKYYKAYLKGKI--ERTNYLQKR-AAAIQLQAAFRRLKAHNLC--RQIRAACVIQSYWR-----------------MR---QDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYR------------GMQARKMYVHILTSVIKIQSYYRAHVSKKEFL--------SLKN-ATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQ-AFVRGYLVRKQMRLQR-----KAVISLQSYFRMRKARQYYLKMYK-------AIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIK 1821
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Match: gi|215273935|sp|Q8IZT6.2|ASPM_HUMAN (RecName: Full=Abnormal spindle-like microcephaly-associated protein; AltName: Full=Abnormal spindle protein homolog; Short=Asp homolog) HSP 1 Score: 231.876 bits (590), Expect = 6.280e-61 Identity = 295/1228 (24.02%), Postives = 547/1228 (44.54%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHR--SRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKH-LNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA---QKRFASMKW-AATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQ-------------TEAQEELEHCS---ATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFV--------QSLAHHLKWKR----MHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHV----ARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA----------------------WRQYQNRLCLER-----RIQACVRIQRGFRKFIQRCC-LQRCLSERIAL---------RHEAQERA----------WTESRSL-----AAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQW---------------ATKI-QSLWRMRMARREFAQIQASALEELKNYSAIL--------------------IQSHWRGCVQRGKFLR---------------------------LRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAG-----------ATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHK---HYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
+L +Q +V IQ S+RR+ + +R+ E+ ++ AT IQS ++MHR R + L++ + ++ L++ SA ++Q+ ++ R ++ +++ ++QS FR RRRF+++K+A + + ++ + KH L + +HL ++A IQ ++ R+M + + Q +A LIQ+ +R + F +H+++ IQ +R + A Q+ +W +A +IQ +++ + Q L E+ ++++ IQS +RM+ Y + Q + Q+ +H T +QA ++ K ++ +AI++Q K + R+ + + + +QR +R+ V QS K ++ MH++AT IQ+ +RM +A+ Y + A + IQ YYR +V R F A +K + TIQ+A+R +VR++ + + + + AA+V QSA W + C + + +A V IQ+ F + + R Q+C + RI R Q+RA W + AA+++Q+H+R + QRQ Y+ +R S I++Q + +G+I +R ++ ++S IQ WRR+ K L + W A KI Q + ++ R F ++ASA+ + + AIL IQ+H+RG R FLR +++ + LQAL + + ++R + R R+ IQRA++ + +++ + S I IQ +R + + H E G + IQ++++ +++RKK + + IQ +RGY R K+DC KI+ +R + + N E+ KL RTALAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRSIP M++I + V +N++KYE + + + ++ ++ L+E+L IYR DK I+TKT LL LL ++NR + + ++ +K H H+++ +++ +++N+ + F P + +L P W +R D + +P A +MV++ L +
Sbjct: 2308 FLQVQNAVIKIQSSYRRWMIRKRMREM------HRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHL---RKAAITIQSSYR---------RLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREK------HKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQK----SVRTIQAAFRGMKVRQKLKNVSEEK-MAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANK------QVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK--KNDCT------------------KIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCEN-MAQSGAISKIFV-LIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYD-VENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLK--PDWVLRRDNMEEITNPLQAIQMVMDTLGI 3475 HSP 2 Score: 160.999 bits (406), Expect = 1.310e-38 Identity = 213/836 (25.48%), Postives = 391/836 (46.77%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL---------------------VQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR--QAFLRIMADAQEELRQY----------SATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSR-------RSYLRFQTEAQEELE-------HCSATLIQAQWRVWI----QLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQ-SAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGF----------RKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR-GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKS 755
R+ +IQ +WR+Y L + L + L +++N A IQ +W+ ++++LL K LE +N++A+LIQ +W+ + R++F LK S++LQS R A + A I + W+ L +K +R ++ S IQ ++ W+ R Q+ ++ Q R++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ+ ++ Y ++Q IQ FR L ++A IQSYWRM R ++ ++FQ ++ + +A +IQ +R +I L +Y++ R + IVLQ+ +G R+ + S +Q +R + ++ + + ++Q+ +M Q R+ YL + A L IQ+ YRS ++A Q + + + I+ A+ R + R++ R+ + +A + +QS +R + R + +A + IQ + + F+Q CL A + R + +S+AA+ IQS +RG+ +R +Y + +S I +Q+ R + D + +++++V +Q A+R + + K ++R HQ A KIQS +RM A+++F + +AL +N+ A W G Q +++ LR + LQ++ K +R+L + A IIQ +R H + +K+K+M ++A+ IQ +R + R HL +L A A T+Q + + VRK+ +A IQ YR Y+ + + +
Sbjct: 1268 RAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVN-AALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQR--YEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAY------VSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS--KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRL---QRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQ---AAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK------QIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRA------WTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH------VQQKKWKIMKKAALLIQKYYRAYSIGREQNHL-YLKTKA--AVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYAT 2065 HSP 3 Score: 147.902 bits (372), Expect = 1.703e-34 Identity = 209/872 (23.97%), Postives = 407/872 (46.67%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQE--LLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRK---------------FIQR-----CCLQRCLSERIALRHEAQERAWTESRSL----------AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGW----IVRRDYERSRSSVRVIQRAWRRFALIKRLEE--------QSEMRL--------RHQWATK-IQSLWRMRMARREFAQ---------IQASALE-------ELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWV----VRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALL 765
Y+ L+ +V ++Q W+ +L ++L+ + ++CA IQS+++MH +++ ++++ L ++ LK + +QS ++ R++ A+V +QS +R K ++++ T + +A +I +W++G H ++ +L+L ++A KIQ ++ R R+ F++ M + Y +A +IQ + R++ + R+ +L + + +Q+ FR ++ M+ AAT+IQ ++R YR ++ F L + +Q R W + ++FQ +L H S IQA +R + K M +A ++Q + + + RR+F S K++A ++QR +R + HHL++ ++ + +IQ+ +R W R+ A IQ +R H + +QA ++ A+ IQ ++ N+ + +RQ ++ R+ +A+++Q+A+R + R L+ + IQ FR F+QR C + L + + LR A + R + AA+LIQ+ +R + + + +SI++Q+ R + + R +Y R S VIQ A++ + L E QS R+ + QWATK IQ +R +++ Q +QA + + ++ +AI+IQ H + R +L LR T + +Q R+L ++R A I +++ R +R ++Q M ++A IQS +RMH+A+ Y + + A IQ +++V RK F+ ++++V IQ +RG +VR K+ + K A++
Sbjct: 1944 YIELRHAVLVLQSMWKGKTLRRQLQ------RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKE-YLNL-KKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYR------QQTYFNKLKKITKTVQQ--RYWAMKERNIQFQR--YNKLRH-SVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTK---HHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQ----ASVVIQQQYQANRAAKLQRQHYLRQRH-SAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQR------RYRKLTAVRTQAVICIQSYYRGFKVR--KDIQN---MHRAATLIQSFYRMHRAKVDYE-------TKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIV 2770
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|584005892|ref|XP_006797936.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein homolog [Neolamprologus brichardi]) HSP 1 Score: 246.128 bits (627), Expect = 4.882e-63 Identity = 296/1145 (25.85%), Postives = 536/1145 (46.81%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLR------------RLKLALELKRNQ------SATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQ-KHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKR----FASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWI----QLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWR----MWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL--AATTIQSAW-----RRN--QVR------RERQRIIQ----------TRNEAALVIQSAWRQY--QNRLCLERRIQACVRIQRGFRKFIQRCCLQR-C-LSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWR-RFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQR----RLVSMRESARIIQRAW----------------RRHR----LIRHLAE------------LQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAE-----------MAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKT-FALLWLLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERG---RRRNNYLPNSF----RPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
Y ++ S +IQ +R L QR L L+ + + A IQS ++ H R+E+ R + + +R + +A IQ+ ++ + R+ A+ V+Q+ FR+ ARRR+L +KRAA +I + ++ L K NE N + WRGR RI E+ Q A+ IQ+ +R H + + R + + +QS +R + A ++ + K A+ +Q ++R R R + + +Q+AT IQ+ RM++ R+ YL L H +A +IQ+Q+R + QL +++++ + + +QA +G+ +R+ + Q +++R +Q +R + + + + ++ IQ ++R M Q QSY ++A + IQ YR H AR RK+ ++ AA+ IQ + R+N VR ++R R + ++ A + +Q+A+R Y + RLC+E A V IQ +R + Q+ +R C + + R+ A ++ E +L AA+++Q+ +RG RQ +++ ++Q+ R R+Y +SSV +QR +R A K+L+ ++R Q A +Q+ R RR+ + L+N++A++IQS WR V+R F R + ++LQ +A R + + +R++A +Q+ W RR R + HL+ L+ K S ITIQ L R + RR Y A+A+ A IQ+++Q +++ ++ R+++ + Q +RG+ R L D P KI ++R ++ + + E+ KL N+T+ ALD L R + +++L LK+L+ TR S CC++++ ++ L+R CNRS+P MD+I+ + + +NL+KY + + + + ++ +ETL+++L YR+K+ D I+TK F L LL R +++ LP ++ ++ R H ER ++ + + SF P ++A PK P W +R D ++ DP A +MV N L++
Sbjct: 1526 YRKIKGSAFLIQAQYR--GLAQRRRFLTLKLQ-HHSAVVIQSAFRGHAVRKEVAEMRCAAVVIQRWCRASMTRDAERKKFVRMKCAAVTIQAAYRGKVARDSLKKQDRAAAVIQAAFRKHAARRRYLILKRAAVLIQQKYRATLLSRKTKNE------YNSLRAAVLTVQANWRGRADRKRI-----EKWHQ-CASFIQACYRRHKVQAEYRAKRAAAVVLQSHYRAYLAGRKMKRGYLEKKAASITVQAAFRGMRV------RAELKKKHQAATVIQALARMFLCRKRYL---------LLHSAAIVIQSQYRALLLCRAQLNEFRKLKQATVKIQAVFRGFRERQDLKRQHKASRAIQAHFRMHRM------RVAYLALKCASIIIQERYRAKRLMDQQMQSYRTMKHAVIVIQAAYRGHKAR------RKIANMHQAASVIQRKFLAIRDRKNFLAVRVAVLACQQRYRAVTLTRKARLDYLSKRRAVVCLQAAYRGYVVRKRLCIEH--MAAVTIQSQYRMYQQKNNYKRLCWAATVLQTRYRANKKMRAEVHALSVKKNAAVVLQAAFRGMKLRQMIKQKHQAASVIQRAYRAHCEHREYLTLKSSVLTVQRRYRASVAAKKQLQTYQKLRRLKQSAIVLQATLRGWRVRRDVS---------LQNHAAVVIQSCWRCLVERRVFQRKKAAAVKLQQRIRAVQLGRQERSKYIQLRQAAITLQKHWQAWIARQQVVKAARVERRLRFTSAIFHHLSAIKIQRALRAHWALESAKRQIHSVITIQRLVRARQQRRRYLEYKQKVATAQRAVRHWLARRHKAATVIQQAVQKFLLLRRQKRVQQGILKAQALWRGHCSRR-------------LNDNP-------KIVKLRHRLRVVTASVREEDKLCNKTSSALDYLLRYKHFSYILEALKNLETATRLSPECCERLVESG--ATNVIFTLIRCCNRSVPCMDVITFSIQILLNLSKYHKT-IEAVYSVENSVETLLDLLQRYREKAGDKVAEKGGSIFTKACFLLALLLQDKQRTEEVKKLPKVLDRIHSIYRLTARKHKMDTERTIIKQKMSASINGSFFVPVTPRKSRAAPK-----FAPDWVLRRDKLKDIVDPLRAIQMVANTLSI 2589 HSP 2 Score: 145.206 bits (365), Expect = 2.855e-31 Identity = 210/821 (25.58%), Postives = 382/821 (46.53%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKI---------------------NQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQ-GY---------------------WKMWRGRQAFLRIMADA--------QEELRQY-----SATLIQSQWRSHSERKAFLHLR---HSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSAR----VLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRI---QACVRIQRGFRKFIQRCCLQRCLSE-----RIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
R+ +IQ +WR+Y L + LE L ER + NQ A IQ+ W+ + +R++L R + L ++++AT+IQ+ W+ + L+ ++V+Q+ +R +A + + A+ VI K+ + K +R H L+ + KIQ GY +K W GR+ R A Q+ L QY SA LIQ+Q+R ++R+ FL L+ HS + IQS FR + +K A M+ AA +IQR W + ER +F + +A IQ+ +R ++R S L+ Q A A +IQA +R + Y ++ +A+++Q + + + R+ +++ S R +Q +WR A + ++ HQ A+ IQ +R + + Y + A + +Q +YR+++A + + A+ T+Q+A+R +VR E ++ +++AA VIQ+ R + LC +R + A + IQ +R + C Q L+E + ++ +A R + E + L A+ IQ+H+R R Y+ L+ +SI++Q++ R + + Y + +V VIQ A+R +++ HQ A+ IQ + R+ F ++ + L + Y A+ + R +L RR + LQA + + ++RL +A IQ +R ++ + YK + +A +Q+ +R +K R H + +A + R M++ R+ + +A +VIQ+ YR +
Sbjct: 1310 RAARVIQGAWRKYKLKKDLE-LYKERNMAAMKIQVFVRNFLQRRRAKRQNQAAVVIQTSWRGYAARKKLRLRKQAQLRAMQHEAATVIQAQWRMFSTMRAYQCLRYHTIVVQAQWRMRRAASAYGKIYWASTVIQKYSRAWAISKR--DRAHYLLLRSAVVKIQRGYRRWKAQKIQKENCAVRVIQAAFKKWYGRKMSQRTAAAVRIQSWYRMQKCLNQYRKIKGSAFLIQAQYRGLAQRRRFLTLKLQHHSAVVIQSAFRGHAVRKEVAEMRCAAVVIQR-WCRASMTRDA-ERKKFVRMKCAAVTIQAAYRGKVARDS-LKKQDRA--------AAVIQAAFRKHAARRRYLILKRAAVLIQQKYRATLLSRKTKNEYNSLRAAVLTVQANWR------GRADRKRIEKWHQCASFIQACYRRHKVQAEYRAKRAAAVVLQSHYRAYLAGRKMKRGYLEKKAASITVQAAFRGMRVRAE----LKKKHQAATVIQALARMF---LCRKRYLLLHSAAIVIQSQYRALLL-CRAQ--LNEFRKLKQATVKIQAVFRGFRERQDLKRQHKASRAIQAHFRMHRMRVAYLALKCASIIIQERYRAKRLMDQQMQSYRTMKHAVIVIQAAYRGHKARRKIANM------HQAASVIQRKFLAIRDRKNFLAVRVAVLACQQRYRAVTLTRK-----ARLDYLSKRRAVVCLQAAYRGYVVRKRLCIEHMAAVTIQSQYRMYQ------QKNNYKRLCWAATVLQTRYRANKKMRAEVHALSVKKNAAVVLQAAFRGMKL---RQMIKQKHQAASVIQRAYRAH 2080 HSP 3 Score: 92.4337 bits (228), Expect = 4.436e-15 Identity = 111/385 (28.83%), Postives = 179/385 (46.49%), Query Frame = 0
Query: 427 RIIQTRNE--AALVIQSAWRQYQNRLCLE---RRIQACVRIQRGFRKFIQRCCLQR---------------CLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQ-----------------------VRGW-IVRRD---YERSRSSVRVIQRAWRRFALIKRLEEQSEMRL---------------RHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLR---RTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
R++ R+E AA VIQ AWR+Y+ + LE R A ++IQ R F+QR +R +++ LR +AQ RA AA +IQ+ WR ++ + Y LR +I+VQ Q R W I +RD Y RS+V IQR +RR+ K +E +R+ R A +IQS +RM+ ++ +I+ SA LIQ+ +RG QR +FL L+ + + +Q+ + ++ + MR +A +IQR W R + R AE +K+ M +A+TIQ+ +R AR + + A A IQ + + R++++ ++RA +IQ+ YR
Sbjct: 1301 RLLDLRDETRAARVIQGAWRKYKLKKDLELYKERNMAAMKIQVFVRNFLQRRRAKRQNQAAVVIQTSWRGYAARKKLRLRKQAQLRAMQHE---AATVIQAQWRMFSTMRAYQCLRYHTIVVQAQWRMRRAASAYGKIYWASTVIQKYSRAWAISKRDRAHYLLLRSAVVKIQRGYRRWKAQKIQKENCAVRVIQAAFKKWYGRKMSQRTAAAVRIQSWYRMQKCLNQYRKIKGSAF---------LIQAQYRGLAQRRRFLTLKLQHHSAVVIQSAFRGHAVRKEVAEMRCAAVVIQR-WCRASMTRD-AERKKFVRMKCAAVTIQAAYRGKVARDSLK-------KQDRAAAVIQAAFRKHAARRRYLILKRAAVLIQQKYRA 1664 HSP 4 Score: 91.2781 bits (225), Expect = 1.017e-14 Identity = 134/519 (25.82%), Postives = 235/519 (45.28%), Query Frame = 0
Query: 325 SQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVA----RLAFQAE-RKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWR-------------------QYQNRLCLERRI--------QACVRIQRGFRKF----IQR--CCLQ-----------RCLSERIALRHEAQ-----ERAWTESRSL--AAILIQSHWRGWTQRQRYIGLR---KSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMAR-------REFAQIQASALEE-------LKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYR--HLTHLAAS-------------AEM-----AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
+ R+ARV+Q +WR++K + L +K + +A +IQ R + R+ R A + IQ +R + A RL QA+ R ++ AAT IQ+ WR R Q +V+Q+ WR +Y + +R A V+IQRG+R++ IQ+ C ++ R +S+R A Q ++ + R + +A LIQ+ +RG QR+R++ L+ S++++Q RG VR++ R + VIQR W R ++ + E + +R++ A IQ+ +R ++AR R A IQA+ + + +A+LIQ +R + + ++ LR + +QA + ++R+ + A IQ +RRH++ +Y+ +A+ +QS +R + A R + +L AAS AE+ A IQ +M++ RK+++ + A VIQ YR
Sbjct: 1307 DETRAARVIQGAWRKYKLKKDLEL---YKERNMAAMKIQVFVRNFLQRRRAKRQNQAAVVIQTSWRGYAARKKLRLRKQAQLRAMQHEAATVIQAQWRMFST----MRAYQCLRYHTIVVQAQWRMRRAASAYGKIYWASTVIQKYSRAWAISKRDRAHYLLLRSAVVKIQRGYRRWKAQKIQKENCAVRVIQAAFKKWYGRKMSQRTAAAVRIQSWYRMQKCLNQYRKIKGSAFLIQAQYRGLAQRRRFLTLKLQHHSAVVIQSAFRGHAVRKEVAEMRCAAVVIQR-WCRASMTRDAERKKFVRMKCA-AVTIQAAYRGKVARDSLKKQDRAAAVIQAAFRKHAARRRYLILKRAAVLIQQKYRATLLSRKTKNEYNSLRAAVLTVQANWRGRADRKRIEKWHQCASFIQACYRRHKV------QAEYRAKRAAAVVLQSHYRAYLAGRKMKRGYLEKKAASITVQAAFRGMRVRAELKKKHQAATVIQALARMFLCRKRYLLLHSAAIVIQSQYRA 1810
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|443696752|gb|ELT97378.1| (hypothetical protein CAPTEDRAFT_220529 [Capitella teleta]) HSP 1 Score: 246.128 bits (627), Expect = 5.234e-63 Identity = 307/1125 (27.29%), Postives = 532/1125 (47.29%), Query Frame = 0
Query: 11 IIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWR-------GRQAFLRIMA------DAQE--ELRQYSATLIQSQWR------SHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMK----WAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATL-IQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR--------RFKFVQSL--------AHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLER------RIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRG----WTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFAL-----IKRLEEQSEMRLRHQW------ATKIQSLWRMRM----ARREFAQ-------IQAS--ALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMR---ESARIIQRAWRRHRL--------IRHLAELQKYKVMTQ---SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYR---GYQVRTAF------KSDCKIKQTALLPDFPINE----------ELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVDIYTKTFALLWLLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERGRRRNNYLPNSFRPS-------PAQAK-PKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLALK 1018
+IQR +R L R+++L I A +QSF++ ++ KLA KR ++A IQ +K + R +F ++ V+LQS R+ + RRRFL ++ A V+ W+ +H ER + +A +Q ++K R R F+R+ A ++Q+ ELR ++I+ Q R +R+ FL LRH+ +Q+ FR AQ+ ++++ AA +Q + R +H +R N +A IQ WR R R E+L +AT+ IQ WR + Y+++R +AI +Q+ K QR +F + SA +QR +R R + Q A+ + ++ + IQ+ R W+ R++YLR +++ + IQ+ YR + R+ + A + AA +Q WR N ++++ T+ AA+ IQ+ ++ + R ++ A +R +R ++F+ L+R AAI+IQ WR +R ++ R +++ +Q RG +VRR R R++V IQ WR F ++++ Q+ ++ RHQ+ AT IQ +R +M R++F IQ + A + +N +A IQ+ +R K+ R + ++ Q+ + +A+++L +R +A IQRA+RRH++ R LQ+Y + + A+ IQ W H + LA + IQR ++ +VR KF+R AV V+QK + ++TA K + K + ALL I SK + +R++V AN AT D++LGNR A+D L++ + +A++L + D+DV TRFS CC +++ V ++ L+R CNRS+PHM+I+ ++V +NLAKYE +R + + + ++ LIE+L IYR+K I+TK LL +L + +K + KK++E H+L +++ + + R + N S P A K P++S P W + ++ ++ +DP A V++ L L+
Sbjct: 2674 VIQRRFRAMKLA-RIQQLYFH-VIRGAAIVLQSFFRAIMAK-------KLA---KRMKAAVCIQRTYKGFVARREFLLKRSQIVLLQSLVRREQERRRFLKIRSAVIVMQAQWRAVRIGRH--ERRCFLIRKGAAITLQAWFKGQRLHRDYLIMRNGFIRLQALHRRNIESQKFSELRD---SVIKMQRRRRAISAGREDRQRFLRLRHAATCVQNLFRVKQAQREASAIRKQRHAAAVKVQSAVRGLLARRHFSKR------NVAALMIQRRWRAVRDGRLVRR------EQLMRTAATMVIQNAWRKTSAQRRYQRLRQAAIRVQSLCKAKKQRLEFCKSRASAVTIQRWFRTVLHTRQCRSAYEQKKQAVVIVQRAYRARLQQRTAAVVCIQSHMRSWKQRENYLRLRHSAVLIQRMYRGYKERIRYNALKN----AALVLQRLWRCNTAAKKQRLAYLTQKRAAISIQAWFKMHSARSAFRSQKVGFAKLSAVIRGRRQRKRFV---ALKR-----------------------AAIVIQQRWRAEKLCQKKRGEFLLRRTAAVSLQAIFRGMLVRRQTRRVRAAVS-IQSFWRMFRARENYKVEKMLIQAAVKSRHQYQVKISAATSIQWWFRSKMLLKQTRKDFLSKKRAVIIIQKAYLAYKLRRNEAATRIQACFRRFAACKKYQHTRASVVQAQSFVRGYLAKKKLRDLRMKWHAALAIQRAFRRHQIKTKLKLENTRRSEYLQRYCCVVRYHLMAVRIQRAW-------HKKQSIVLAQKHLSSVIVIQRWLKTILVRAKFLRQLAAVRVVQKAKKRDAACILQTAVRRWLAKKQEEKFTEAALL----IQSHWRGRKVRRASTSKALRNIRKQVLEANRKATVDQRLGNRMRRAVDNLFKYKQLAYVLQAVMDIDVATRFSHVCCRELVEHG--AVPVIFRLIRSCNRSVPHMEIVKYSVNVLLNLAKYEETRGAVYQ-EEGSIDCLIELLQIYREKGA-IFTKVCTLLGVLCYDPQSRKEV---FENKKVVEKLNSLHKLTSRKHKMNKDRKT-VQNKMAASRSLSSTMPIMAPVVKTPRVS--PDWVLSKNKMQEIEDPMAAINFVMDTLRLR 3717 HSP 2 Score: 182.185 bits (461), Expect = 1.065e-42 Identity = 235/839 (28.01%), Postives = 402/839 (47.91%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQ----RLEELILERKINQCATQIQSFWKMHRSRQELLRR---LKLALELKRN-----QSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWK------------GCL---------FQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKW----SAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRR------FKFVQSLAHHLKWK-RMHQ----------SATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWAT-KIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY---------------------RHLTHLAASAEM------------------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
+L Q++V +IQ +R + L + + + I +K+ +C Q+F + + ++ RR L A E+++ +S +QS ++ +RE C K A++ +QS FR +ARR FLT KRAA VI + + C+ +Q+ +R + +A IQ +KM RQ FL+ A A + IQS +R RK + L+ TL +Q +FR ++RF +++ AA++IQR++R + +R + +A +IQ+ +RM R++YL ++ +A IQ +R+ Q +AY R +AI +QA + QR+ + + + +A +Q ++RR + +S A ++ RMHQ +A +IQ +RM Q RQ+YL T++A + IQ YR H R A+ R AA IQ+A+RR+Q +RQ + TR+ AA+ IQ+A+R +Q+R A ++IQ +R RH+ Q +A+ +RS AAI IQ+ +R QRQ Y+ R ++I +Q R R+ Y +RS+ IQ A+R + +Q + L + A +IQ+ +RM R+ + +++A++ IQ+ +R QR +L R I++QA+ + ++ ++ R +A IQ A+R H+ + Q Y +AI IQ+ +RMH+ R+ Y +LT +A+ ++ A IQ M+M + R +FIR +R+V V+Q+H+ G
Sbjct: 1850 FLKTQKAVVLIQSVYRMHVLCKGYQSKRQAAITIQKMVRCRQAKQAFGDLKETTLKVQRRWRCLLQAREIRKGFLTLRRSVLRMQSLYRQ--RREVECRQKRAALAIQSAFRMYRARRAFLTQKRAAIVIQRELRRVRCQTDYMHTVACVRKLQQYFRSYQQMKEDRAKFVRVKHAACFIQATFKMNIARQNFLQQKAVAVQ---------IQSWFRCRITRKRYEALKRGTLLLQRKFRAHKLMEDHRRRFLNLRKAASLIQRTYRAKQ-----QKRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRS---------AAIQIQTAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRRHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQTAYRMHQQRHAYLTTRS----AAIQIQAAYRRHQ---QRQAYLTTRS-AAIQIQAAYRMHQHRQAYLTTRSAAIQIQAAYR------------------RHQ-QCQAYLTTRS-AAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRRHQQRQAYLTTRSAAIQIQAAYR-------MHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQ---------IQAAYRMHQQRQAYLTTRSAAIQIQAVYRMHQQRQAYLTTRSAAIQIQAAYRMHQ------QRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAVYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQSFMRMLLARSQFIRQKRSVVVLQRHFTG 2613 HSP 3 Score: 180.644 bits (457), Expect = 3.003e-42 Identity = 210/778 (26.99%), Postives = 384/778 (49.36%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSAT-KIQSYWRMWMSRRSYLRFQTEAQE------ELEHCSATL--------IQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR----RFKFVQSLAHHLKWK---RMHQ----------SATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERI----ALRHEAQERAWTESRSLA----------------------AILIQSHWRGW----TQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLE-----------------EQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY 700
+L L+++ +IQR++R + Q+ + + R A QIQ+ ++MH+ RQ L A++ IQ+ ++ H QR+ + ++A++ +Q+ +R + R+ +LT + AA I ++ +H + +L+ + +A +IQ ++M + RQA+L + +A IQ+ +R H +R+A+L R + ++IQ+ +R + + + + AA IQ ++R H++ Q L +SA +IQ+ +RM R++YL ++ A + + C A L IQA +R+ Q +AY R +AI +QA + QR+ + + + +A +Q ++R R ++ + + ++ + RMHQ +A +IQ +RM Q RQ+YL T++A + IQ YR H R A+ R AA IQ+A+R +Q +RQ + TR+ AA+ IQ+A+R +Q R A ++IQ +R QR S I A R Q +A+ +RS A +++Q H+ G T R+R+I + S+I++Q+ R +++RR+ +R +++VR +Q AWR + L KR +Q + A +QS +R MA++ +++A A+ IQ ++G V R +FL R + LQ+L + +RR + +R + ++Q WR R+ RH E + + + +AIT+Q+ ++ + R Y
Sbjct: 2090 FLNLRKAASLIQRTYR--AKQQKRQAYLTTRS---AAIQIQAAYRMHQQRQAYLTTRSAAIQ---------IQTAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYR-----RHQQRQAYLTTRS-AAIQIQAAYRMHQQRQAYLTTRS---------AAIQIQAAYRMHQQRQAYLTTRSAAIQIQTAYRMHQQRHAYLTTRSAAIQIQAAYRR-------HQQRQAYLTTRSAAIQIQAAYRMHQHRQAYLTTRSAAIQIQAAYRRHQQCQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRRHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAVYRMHQQRQAYLTTRS----AAIQIQAAYRMHQ---QRQAYLTTRS-AAIQIQAAYRMHQQRQAYLTTRSAAIQIQAVYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQSFMRMLLARSQFIRQKRSVVVLQRHFTGLLLMKTMRERFICKKTSAIVIQRAYRNYLLRRNDKRRQAAVR-LQTAWRAYTLRKRTNACIVIQRRFRAMKLARIQQLYFHVIRGAAIVLQSFFRAIMAKKLAKRMKA----------AVCIQRTYKGFVARREFLLKRSQIVLLQSLVRREQERRRFLKIRSAVIVMQAQWRAVRIGRH--ERRCFLIRKGAAITLQAWFKGQRLHRDY 2810 HSP 4 Score: 171.785 bits (434), Expect = 1.727e-39 Identity = 211/739 (28.55%), Postives = 365/739 (49.39%), Query Frame = 0
Query: 57 RLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATL-IQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGW----IQRRQFESQKRSARVLQRSWR-----RFKFVQSLAHHLKWK---RMHQ----------SATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERI----ALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWAT-KIQSLWRMRMARREFAQIQASALEELKNY--------------SAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
RLK LK ++ LIQS ++ H+ + + + + A++ +Q R +A++ F +K + + W+ CL Q + L+L RS ++Q ++ R + E RQ A L IQS +R + R+AFL + + + IQ E R+ Q + +Q+ +R Y+ Q +R +F + +A IQ+ ++M ++R+++L+ + A IQ+ +R I K Y+ ++ ++LQ + + RR+F + +++A ++QR++R R ++ + + ++ + RMHQ +A +IQT +RM Q RQ+YL T++A + IQ YR H R A+ R AA IQ+A+RR+Q +RQ + TR+ AA+ IQ+A+R +Q R A ++IQ +R QR S I A R Q A+ +RS AAI IQ+ +R QRQ Y+ R ++I +Q R R+ Y +RS+ IQ A+RR +Q + L + A +IQ+ +RM R+ + +++A++ Y +AI IQ+ +R QR +L R I++QA + ++ ++ R +A IQ A+R H+ + Q Y +AI IQ+++RMH+ R+ Y LT +A+ + IQ + +M R+ ++ R A IQ YR +Q R A+
Sbjct: 1844 RLKRMEFLKTQKAVVLIQSVYRMHVLCKGYQSKRQAAITIQKMVRCRQAKQAFGDLKETTLKVQRRWR-CLLQAREIRKGFLTL-RRSVLRMQSLYRQRR------------EVECRQKRAALAIQSAFRMYRARRAFLTQKRAAIVIQRELRRVRCQTDYMHTVACVRKLQQYFRSYQ--QMKEDRAKFVRVKHAACFIQATFKMNIARQNFLQ---------QKAVAVQIQSWFRCRITRKRYEALKRGTLLLQRKFRAHKLMEDHRRRFLNLRKAASLIQRTYRAKQQKRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQTAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRS----AAIQIQAAYRRHQ---QRQAYLTTRS-AAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQTAYRMHQQRHAYLTTRS-AAIQIQAAYRRHQQRQAYLTTRSAAIQIQAAYRMHQHRQAYLTTRSAAIQIQAAYRR-------HQQCQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRRHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRMHQ------QRQAYLTTRSAAIQIQAVYRMHQQRQAY--LTTRSAAIQ-----IQAAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAY 2528 HSP 5 Score: 157.147 bits (396), Expect = 6.838e-35 Identity = 215/805 (26.71%), Postives = 365/805 (45.34%), Query Frame = 0
Query: 37 CATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNER----------IHLSLMN----------RSATKIQGYWKMW--------------------------------RGR----QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQ-RCCLQRCLSERIALRHEAQE--------RAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWR--RFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQA---LAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASA---------EMAGATIQRSMQMWV--------VRKKFIRIRRAVTVIQKHYRGYQVR 750
A QIQ+ ++MH+ RQ L A++ IQ+ ++ H QR+ + ++A++ +QS R AR +F+ KR+ V+ + + G L K + ER I + N ++A ++Q W+ + RG Q+F R + + R +A IQ ++ R+ FL R + +QS R+ ++RF ++ A ++Q WR R + HER F + +A +Q++++ R YL + +QA R I+ + + ++R S I +Q A G R++F + +A +Q + R K Q A ++ +R H +A ++Q+ R AR+ + + A L IQ+ +R+ + E+ + + A IQ+AWR+ +R QR+ Q AA+ +QS + + RL + + V IQR FR + R C R A + Q RA + R+ A + IQSH R W QR+ Y+ LR S++++Q+ RG+ R Y +++ V+QR WR A +RL ++ R A IQ+ ++M AR F + Q +L SA++ RG QR +F+ L+R I +Q K C +R +R +A + +A R L+R Q +V ++A++IQS WRM +AR +Y+ L +A +++ AT S+Q W RK F+ +RAV +IQK Y Y++R
Sbjct: 2534 AAIQIQAVYRMHQQRQAYLTTRSAAIQ---------IQAAYRMHQQRQAYLTTRSAAIQIQSFMRMLLARSQFIRQKRSVVVLQRHFTGLLLMKTMRERFICKKTSAIVIQRAYRNYLLRRNDKRRQAAVRLQTAWRAYTLRKRTNACIVIQRRFRAMKLARIQQLYFHVIRGAAIVLQSFFRAIMAKKLAKRMKAAVCIQRTYKGFVARREFLLKRSQIVLLQSLVRREQERRRFLKIRSAVIVMQAQWRAVRIGR--HERRCFLIRKGAAITLQAWFKGQRLHRDYL---------IMRNGFIRLQALHRRNIESQKFSELRDSVIKMQRRRRAISAGREDRQRFLRLRHAATCVQNLF-RVKQAQREASAIRKQR-HAAAVKVQSAVRGLLARRHFSKRNVAALMIQRRWRAVRDGRLVRREQLMRTAATMVIQNAWRKTSAQRRYQRLRQ----AAIRVQSLCKAKKQRLEFCKSRASAVTIQRWFRTVLHTRQC-------RSAYEQKKQAVVIVQRAYRARLQQRTAAVVCIQSHMRSWKQRENYLRLRHSAVLIQRMYRGYKERIRYNALKNAALVLQRLWRCNTAAKKQRLAYLTQKRA----AISIQAWFKMHSARSAF-RSQKVGFAKL---SAVI-----RGRRQRKRFVALKRAAIVIQQRWRAEKLCQKKRGEFLLRRTAAVSLQAIFRGMLVRR----QTRRV--RAAVSIQSFWRMFRARENYKVEKMLIQAAVKSRHQYQVKISAAT---SIQWWFRSKMLLKQTRKDFLSKKRAVIIIQKAYLAYKLR 3283 HSP 6 Score: 155.992 bits (393), Expect = 1.439e-34 Identity = 206/749 (27.50%), Postives = 354/749 (47.26%), Query Frame = 0
Query: 36 QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARR----RFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWR----SHSERKAFLHLRHSTLR---------------------IQSEFRKWSAQKRFASMKWAATIIQRSWRHYRF-VQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRM-WQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
+ A QIQ+ ++M +R+ L R RN +A IQ+ ++A +++Q+ +++ A++++Q +R + R FL ++A +I ++ + K + ++A IQ + + +QAF D +E + +Q +WR + RK FL LR S LR IQS FR + A++ F + K AA +IQR R R ++H R L Q +SY +M R ++R ++H +A IQA +++ I + + Q + A+ +Q+ + I R+++E+ KR +LQR +R K ++ H ++ + ++A+ IQ +R Q RQ+YL T++A + IQ YR H R A+ R AA IQ+A+R +Q +RQ + TR+ AA+ IQ+A+R +Q R A ++IQ +R RH+ Q +A+ +RS AAI IQ+ +R QRQ Y+ R ++I +Q R R+ Y +RS+ A +IQ+ +RM R + +++A++ IQ+ +R QR +L R I++QA + ++ ++ R +A IQ A+RRH+ + Q Y +AI IQ+ +RMH+ R+ Y LT +A+ ++ A +R Q R+ ++ R A IQ YR +Q R A+
Sbjct: 1782 KAAVQIQAAYRMLAARRAFLDR--------RN-AAVAIQAWYRAVREQQQYSSMQMAAILIQHKWRAVRDGRLKRMEFLKTQKAVVLIQSVYRMHVLCKGYQSK------RQAAITIQKMVRCRQAKQAF----GDLKE-----TTLKVQRRWRCLLQAREIRKGFLTLRRSVLRMQSLYRQRREVECRQKRAALAIQSAFRMYRARRAFLTQKRAAIVIQRELRRVRCQTDYMHTVACVRKLQQY---FRSYQQMKEDRAKFVR--------VKH-AACFIQATFKMNIARQNFLQQKAVAVQIQSWFRCRITRKRYEALKRGTLLLQRKFRAHKLMED--HRRRFLNLRKAASLIQRTYRAKQQKRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRS----AAIQIQTAYRMHQ---QRQAYLTTRS-AAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYR------------------RHQ-QRQAYLTTRS-AAIQIQAAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAYLTTRSA-----------------------------AIQIQTAYRMHQQRHAYLTTRSAAIQ---------IQAAYRRHQQRQAYLTTRSAAIQIQAAYRMHQHRQAYLTTRSAAIQIQAAYRRHQ------QCQAYLTTRSAAIQIQAAYRMHQQRQAY--LTTRSAAIQIQAA-YRRHQQ----RQAYLTTRSAAIQIQAAYRMHQQRQAY 2413 HSP 7 Score: 142.895 bits (359), Expect = 1.489e-30 Identity = 214/824 (25.97%), Postives = 396/824 (48.06%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHL----------------NERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKR----FASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRF--------------KFVQSLAHHLKWKRM--HQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLES--LAATTIQSAWRR-NQVRRERQRIIQTRNEAALVIQSAWR------QYQNRLCLERRIQACVRIQRGFRKF--IQRCCLQ-----RCLSE------------RIALRHEA--QERAWTESRSL-AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSE-MRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKAC----IAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
Y R+V ++QR+ RR+ LV+R E+ ++ A +Q W+ R + + + K N SA +IQ + ++ R + A++ +Q +RQ RR+FL ++ I + ++ L + + R +L N++A KIQ +++ R R FL ++ S ++QS +R ++ F LR + +Q R + +R F ++ AA +IQR++R ER ++A IQ +R W S +FQ + Q +A +IQ+ +R + K+Y Q + + +Q+ V+ + + + + +A +LQR WR V +L + KR ++A +IQ +RM AR+++L +NA +AIQ +YR A + +++ S +AA IQ WR R +R ++T+ +A ++IQS +R YQ++ IQ VR ++ + F ++ L+ RCL + R LR ++ ++R E R AA+ IQS +R + R+ ++ ++++I++Q+++R + DY + + VR +Q+ +R + +K E++++ +R++H A IQ+ ++M +AR+ F Q +A A++ IQS +R + R ++ L+R + LQ +A +RR +++R++A +IQR +R + R Q Y +AI IQ+ +RMH+ R+ Y LT +A+ + IQ + +M R+ ++ R A IQ YR +Q R A+
Sbjct: 1421 YKDRSRAVLVLQRAVRRF-LVKRRED-----RLALAAVIVQRLWRWRRMERRINESIAKKRFFKENHSAIVIQGAVRRYLHRIRTVHQHQAAIRIQCTWRQYLCRRKFLVLREVTLTIQRRYRASLVARRMRFEFVLQRSAALVIQSGVRAYLGKRNQAALKIQSWFRARRARGNFLE---------KRNSVIVLQSVYRGIRAQRDFKVLRSVVVCLQRRIRANQSARRERQNFVQLRNAAVVIQRAYRKRMLDLEEWER------EEAAMVIQRAYRRWF---SAWKFQEKCQ------AAVVIQSAFRRHLAQKSYAQQINAIVTIQSWVRMVLVKTRVAEEMEAAYILQRYWRAALIGHRQKQSYQKLRSAVIALQRGFRHKRECREKAAVQIQAAYRMLAARRAFLDRRNAAVAIQAWYR------AVREQQQYSSMQMAAILIQHKWRAVRDGRLKRMEFLKTQ-KAVVLIQSVYRMHVLCKGYQSKRQAAITIQKMVRCRQAKQAFGDLKETTLKVQRRWRCLLQAREIRKGFLTLRRSVLRMQSLYRQRREVECRQKRAALAIQSAFRMYRARRAFLTQKRAAIVIQRELRRVRCQTDYMHTVACVRKLQQYFRSYQQMK--EDRAKFVRVKHA-ACFIQATFKMNIARQNFLQQKAVAVQ---------IQSWFRCRITRKRYEALKRGTLLLQRKFRAHKLMEDHRRRFLNLRKAASLIQRTYRAKQQKR-----QAYLTTRSAAIQIQAAYRMHQQRQAY--LTTRSAAIQ-----IQTAYRMHQQRQAYLTTRSAAIQIQAAYRMHQQRQAY 2183 HSP 8 Score: 104.76 bits (260), Expect = 7.474e-19 Identity = 168/655 (25.65%), Postives = 296/655 (45.19%), Query Frame = 0
Query: 167 DAQEELRQYSATLIQSQWRSHSERKAFLHLRH------STLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERI---QFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWI----QRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQ-VRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWT-ESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRL-----------------RHQWATKIQSLWRMRMARREF-------AQIQA--SALEELKNYS-----AILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWR-MHKARR-----------------HYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF 753
D ++E R +A IQ+ WR ERK ++++ + L +Q R++ ++R + AA I+QR WR R + ++E I +F N SA IQ R ++ R + +H +A IQ WR ++ + + +R + +Q + + + R +F Q+ +A V+Q R + + +Q+A +IQ+ +R +AR ++L +N+ + +Q YR A+ F+ R + +Q R NQ RRERQ +Q RN AA+VIQ A+R+ L R +A + IQR +R++ AW + + AA++IQS +R ++ Y + + +Q VR +V+ + ++QR W R ALI ++QS +L R + A +IQ+ +RM ARR F IQA A+ E + YS AILIQ WR G ++R +FL+ ++ + +Q++ + + + S R++A IQ +++R Q + + ++ + +Q WR + +AR YR + + A IQ + +M+ R+ F+ +RA VIQ+ R + +T +
Sbjct: 1394 DLRDETR--AARKIQAWWR---ERKLQVNIKSYKDRSRAVLVLQRAVRRFLVKRREDRLALAAVIVQRLWRWRRMERRINESIAKKRFFKENHSAIVIQGAVRRYLHRIRTVH---------QHQAAIRIQCTWRQYLCRRKFLVLREVTLTIQRRYRASLVARRMRFEFVLQRSAALVIQSGVRAY-----------LGKRNQAALKIQSWFRARRARGNFLEKRNSVIVLQSVYRGIRAQRDFKVLRSV----VVCLQRRIRANQSARRERQNFVQLRN-AAVVIQRAYRKRMLDLEEWEREEAAMVIQRAYRRWFS---------------------AWKFQEKCQAAVVIQSAFRRHLAQKSYAQQINAIVTIQSWVRMVLVKTRVAEEMEAAYILQRYW-RAALIGHRQKQSYQKLRSAVIALQRGFRHKRECREKAAVQIQAAYRMLAARRAFLDRRNAAVAIQAWYRAVREQQQYSSMQMAAILIQHKWRAVRDGRLKRMEFLKTQKAVVLIQSVYRMHVLCKGYQSKRQAAITIQ------KMVRCRQAKQAFGDLKETTLKVQRRWRCLLQAREIRKGFLTLRRSVLRMQSLYRQRREVECRQKRAALAIQSAFRMYRARRAFLTQKRAAIVIQRELRRVRCQTDY 1990
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|927134973|ref|XP_013911202.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein [Thamnophis sirtalis]) HSP 1 Score: 245.743 bits (626), Expect = 6.053e-63 Identity = 299/1159 (25.80%), Postives = 524/1159 (45.21%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMW-RGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWI----QRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL------AATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSA------WRQYQNRLCLERRIQACVRIQRGFRKFIQR--------CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRR----DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQ--RR-------LVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYR--------HLTHLAASAEMAGAT--------------------------------------------------IQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAF---KSDCKIKQ-------------TALLPDFPINEEL----------------------SKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYR--------DKSVDIYTKTFALLWLLA-SSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERGRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
YL L S+ + Q +WR + +++ ++ Q A IQS+++MH ++ + + A+ L+R A + +A R+ + ALK +V +Q+ +R ++ RR+ + +A I +F+ H + + RSAT IQ ++ + RG++ + +A LR+ S TL Q+ +R R+ S L IQS +R + +K + + A +IQR +R R + +++++ SA +IQ+ +R M R L+ + H +ATLIQ ++ + Q + + ++ +A+ +Q + + + QR +F + +++ V+Q S R L K+MH +A IQ +RM A Y ++ACL IQ++YR A+QA ++ L +A +Q+A+R +VR +++ R+EAA+VIQS W+ Y+N R +Q VR R + QR C+Q+ A R + +A + R AAIL+Q +++ R+ Y+ L+ ++I +Q++ R IV R +Y R+ + +Q +R F + K ++ Q H AT IQ+ +RM + + +++ +A+ + Y + L + H + QA+ K+ I+Q RR L M SA +IQ + + +H Y+++ ++ ITIQS +R AR+ + L H+A + + +Q +++ ++ R++F RI+R+ IQ YRG + R F + I Q T +P +N ++ + + +R + +AN+ + E+KKL NRTA+A+D L + + +++L LKDL+V TR S CC+ + R V + L+R CNRS+P MD+I + V +NL+KYE + + + V ETL+++L IYR +KS I+TKT L L+ S R +IL L K R H ++R R + + S K K+ P W +R+D I+ DP A EMV+N L +
Sbjct: 1353 YLVLYNSIVLFQATWRGTVVRRQM------KRQRQAAVTIQSYYRMHVNQAKFKHFREAAVTLQRWYRAVI-----QARNARQSYLALKETTVRMQAIYRGSRERRKIQRVNQAVICIQ-----AVFKMH-RCNVQYRALKRSATIIQARYRAFCRGQEDRKKYLA-----LRKSSVTL-QAAYRGMKIRQKLRRSHQSVLIIQSYYRMFRERKAYLKLVAATKVIQRWYRASR--DRNAQMYKYKMMKISALQIQAAFR-GMRTRVLLKKR--------HMAATLIQRNFKAFAQRRKFVFLKSAAVTIQRKYRATVLSKHQREKFLTLRQAVIVIQSSIR------GLLARRYVKQMHLAAAAIQATFRMHIASTQYRTRKSACLVIQRHYR------AYQAAKQTRDLYLKQRHSALILQAAYRGMKVRH----VLRKRHEAAVVIQSNYRKLRQWKSYRNIQWAVRLVQGRVRANRESKMAAQRYSSIQKAAICIQK------AFR---RMKARNQRRQEAAILLQRNFKMQRARKDYLALKAAAISLQRKYRALIVMRRQAKEYASVRAKIICVQSFYRGFKVRKEVKRQ------HSAATLIQATFRMHKVKLAYRKLRYAAITMQRFYRSHLQEKHQKA----------------HQAIPKSVISQVTRRGTKIQPELDPMHISATVIQSLYLMYVQQKH------YELICRAVITIQSAYRGMIARKETKRMRAARNGQLCHMAVNDRIEAVESKTQCHSNEAREQRQKYWKAAVLIQQHYRSYLTVKHQSVVYFQTHKRIILLQATVRGFIERQRFARIKRSTIKIQSWYRGNRQRMKFLQYREKIIIIQRMVRRWISHRNINTGGIPK-DVNPQIVSIGVTKFQALWRGYSWRKKTDTPETRSLRDSLIVANKESKEEKKLYNRTAVAIDYLLKYKHFSYILAALKDLEVVTRLSPVCCENMA--QSRAVGTIFTLIRSCNRSLPSMDVIKYSVQVLLNLSKYERTTDAVYSVENSV-ETLLDLLQIYRERPGDKTSEKSGSIFTKTCCLFAHLSKDSRRASEILNNHKTVAGLRSLFKLTARKHQMDVQRMRAKQKKVAYMNGQSSVPLKTKIVTRQR-PDWDLRKDNIKEIVDPLQAIEMVVNTLGI 2419 HSP 2 Score: 147.517 bits (371), Expect = 5.418e-32 Identity = 193/691 (27.93%), Postives = 331/691 (47.90%), Query Frame = 0
Query: 69 SATLIQSHWKAH---IQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRS----HSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMS-RRSYLRFQ-TEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRN--QVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQ 748
+A LIQS W+ + I E A VVLQ H+R+ A +K+A ++ +ERI + +A +Q +++M R RQ FL++ +A++IQ+++R+ S+R+ FL ++ +TLR+Q+ R + ++ AAT IQ + + R+++R L Q++ IQ ++R S + RFQ T+A + +QA +R W K ++ + +A+ +Q+ + + ++F + +A +Q+ +R + S ++ ++ S Q WR R+ R + A + IQ YYR HV + F+ R+ AA T+Q W R Q R RQ + + E + +Q+ +R + R ++R QA + IQ F+ + RC +Q +R A +A+ RA+ RG R++Y+ LRKSS+ +Q RG +R+ RS SV +IQ +R F + + L+ ATK+ W R +R AQ+ + ++ SA+ IQ+ +RG R + +Q KA +R+ V ++ +A IQR +R L +H E K+ + Q+ I IQS R ARR+ + + HLAA+A IQ + +M + ++ + A VIQ+HYR YQ
Sbjct: 1098 AAQLIQSAWRKYRLKILAETKKHKSNAVVVLQKHWRRYLAAMELQKLKKA-------------KQEESERIAIQRCEEAAVVLQSWYRMKRERQRFLKMSG---------AASVIQTRYRARREQSSQRQRFLQIKKATLRLQASCRGFKVRRMLRHQHTAATKIQAA------YRAYAARMKYRRLIQASLVIQKWFRASKSGSKMRKRFQKTKA-------AVVSLQAVFRGWQVRKWLRRQQAAALTIQSAYRTYKAMKKFRRVRSAALTIQQHYR--AHIASRKQQREYLVLYNSIVLFQATWRGTVVRRQMKRQRQAAVTIQSYYRMHVNQAKFKHFRE----AAVTLQR-WYRAVIQARNARQSYLALK-ETTVRMQAIYRGSRERRKIQRVNQAVICIQAVFK--MHRCNVQYRALKRSATIIQARYRAFC--------------RGQEDRKKYLALRKSSVTLQAAYRGMKIRQKLRRSHQSVLIIQSYYRMF-------RERKAYLKLVAATKVIQRW-YRASRDRNAQMYKYKMMKI---SALQIQAAFRGMRTRVLLKKRHMAATLIQRNFKAFAQRRKFVFLKSAAVTIQRKYRATVLSKHQRE--KFLTLRQAVIVIQSSIRGLLARRYVKQM-HLAAAA------IQATFRMHIASTQYRTRKSACLVIQRHYRAYQ 1709 HSP 3 Score: 124.79 bits (312), Expect = 5.913e-25 Identity = 207/878 (23.58%), Postives = 380/878 (43.28%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSL-----------------------------VQRLE-------ELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKA----HIQREQFCALKTASVVLQSHFRQTKARR-----------------------RFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSA----QKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLK----AYKQMRCSAIVLQAQVKGWIQRR-----------------------QFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRI-IQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWT----QRQRYIGLRKSSIMVQKQVRGWIVRR-----------------------DYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRL----RRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVV----RKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
R+ +IQ +WR+Y L +Q+L+ E I ++ + A +QS+++M R RQ LK + +A++IQ+ ++A QR++F +K A++ LQ+ R K RR ++ + +A+ VI KW++ + +R + + +Q ++ W+ R+ R +Q +A IQS +R++ K F +R + L IQ +R A Q+ + + + + Q +WR R Q + Q+A IQSY+RM +++ + F+ +A +Q +R IQ + +Y ++ + + +QA +G +RR Q+ + KRSA ++Q +R F + K+ + +S+ +Q +R + RQ R+ + L IQ YYR R A+ L+ +AAT + W R R Q + +AL IQ+A+R + R+ L++R A IQR F+ F QR R + +S AA+ IQ +R QR++++ LR++ I++Q +RG + RR Y +S+ VIQR +R + K+ + ++ RH A +Q+ +R R + ++ +A++IQS++R Q + + R R++A ++ +A +R S++++A IQ+A+RR + A Q+ + ++AI +Q ++M +AR+ Y LA A A ++QR + +V K++ +R + +Q YRG++VR K
Sbjct: 1097 RAAQLIQSAWRKYRLKILAETKKHKSNAVVVLQKHWRRYLAAMELQKLKKAKQEESERIAIQRCEEAAVVLQSWYRMKRERQRF---------LKMSGAASVIQTRYRARREQSSQRQRFLQIKKATLRLQASCRGFKVRRMLRHQHTAATKIQAAYRAYAARMKYRRLIQASLVIQKWFRASKSGSKMRKRFQKT--KAAVVSLQAVFRGWQVRKWLRR---------QQAAALTIQSAYRTYKAMKKFRRVRSAALTIQQHYRAHIASRKQQREYLVLYNSIVLFQATWRGTVV------RRQMKRQRQAAVTIQSYYRMHVNQAKFKHFRE---------AAVTLQRWYRAVIQARNARQSYLALKETTVRMQAIYRGSRERRKIQRVNQAVICIQAVFKMHRCNVQYRALKRSATIIQARYR--AFCRGQEDRKKYLALRKSSVTLQAAYRGMKIRQKLRRSHQSVLIIQSYYRMFRERKAY-----LKLVAATKVIQRWYRASRDRNAQMYKYKMMKISALQIQAAFRGMRTRVLLKKRHMAATLIQRNFKAFAQR-------------------RKFVFLKS-AAVTIQRKYRATVLSKHQREKFLTLRQAVIVIQSSIRGLLARRYVKQMHLAAAAIQATFRMHIASTQYRTRKSACLVIQRHYRAYQAAKQTRDLY-LKQRHS-ALILQAAYRGMKVRHVLRK---------RHEAAVVIQSNYRKLRQWKSYRNIQWAVRLVQGRVRANRESKMAAQRYSSIQKAAICIQKAFRRMK-----ARNQRRQ---EAAILLQRNFKMQRARKDY-----LALKA--AAISLQRKYRALIVMRRQAKEYASVRAKIICVQSFYRGFKVRKEVK 1886
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|663290543|ref|XP_008501536.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein [Calypte anna]) HSP 1 Score: 246.128 bits (627), Expect = 6.173e-63 Identity = 332/1253 (26.50%), Postives = 566/1253 (45.17%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLA-------------------------------------LELKR-----NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTK----ARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYW---KMWRGRQAFLRIMADAQEELRQY---------------SATLIQSQWRSHSERKAFLHLRH-STLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRF----VQH-----------------LHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEA---------------------------------------QEELEH--CSATLIQAQWRVWIQLKAYKQMRCSAIVLQ----AQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATR-----IQTQWRMWQARQSYLRTQNACLAIQKYYRS-HVARLAFQAERKLESLAATTIQSAWRRNQVRR-------------------ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFI----QRCC-LQRCLSERIALRHEAQERAWTESRSL-----AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRR------FALIK----------RLEEQSEMRLRHQW-ATK----------IQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRE---------------SARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWR--MHKAR--RHYRHLTHLAASAEM-------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALLWLLA-SSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMERG---RRRNNYLPNSFRPSPAQAKP-KMPKLS-LCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
YL L++S I+Q ++R + Q L+ + +Q A +IQS+++MH+ +++ R+L LA ++ +R N+SA +IQ ++ ++R+ F +LKTA++V+Q +R TK R+++L AA I ++G + +K + + M+++AT IQ KM+ QA Q+ R Y SA +Q+ +R R+ FL RH + L IQ +R + + + ++WA +IQ+ +R VQH + + Q + L+++A +Q ++ + R+ YL + A ++++EH +A+ IQ+ +++ ++Y+ MR +AIV+Q + VKG QR+++ KRSA V+Q S+R K Q L K MH SAT+ IQ+ +R +AR Y Q + LAIQ++YR+ +ARL QAE + A IQSA+R Q R+ +R++ IQ R AA+ +Q+ + ++ + R +A V +QR +R + QR LQ + R + +A+ R + E + I IQ+ +RG+ RQ ++ +++ ++Q RG R++Y + RVIQ +RR F +K R + M +R+Q+ ATK IQ +R ARR+ AQ +A+A ++IQ H R G +Q K+ R R I+LQA + + ++++ ++ SA IQRA+R H LI LA+ Q S + IQ +R M + R R Y+ + L A A IQR+ + ++ ++ R + Q +RGY R D P + L + +E+ ANE + E+ KL NRTA+A++ L + + I+++L LK L+V TR S CC+ + C + L+R CNRS+P MD+I + V +N++KYE + + E + + +TL+++L +YR K+ D I+TKT LL +L+ S R +I ++P + +K R H ER + N +L + S P ++ +S + P W +R+D ++ DP A MV++ L +
Sbjct: 2095 YLELKKSALILQSAFRGMKVRQNLKVM------HQSAAKIQSYYRMHKQQKDF-RKLLLATRHIQQWFRACKERDVQVHNYMIMKSAALHIQAAFRGMKTRRLVRTMNESAGVIQRRFRTFVKRKHFLSLKTAAIVIQRKYRATKLAKIQRQQYLCFLNAAVTIQSAYRGFVVRKKIQQ------MHQAATVIQATLRMHKMYISYQAVRLASVIIQQRYRAYREGKRVRERYLKLYNSAVALQAAYRGMKTRR-FLKRRHEAALTIQKNYRMYRQYQHYRKVQWATQLIQKRYRANNLRKIAVQHYSSLKKAAICIQKAFRDMQAKKQRQELHRAAIIVQKNFKAFRERQRYLSLKASALVFQRRYRALVLSRQCASEYLSLRRAAIQIQAVYRGIRVRKDIEHMHLAASTIQSAYKMHRNRQSYENMRTAAIVIQNYYRSCVKGKNQRKKYLMMKRSALVIQASYRGMKQRQKL------KIMHMSATKAAAIMIQSMFRGQRARSHYKLIQRSALAIQRWYRACQMARLQ-QAEYSAQRRAIVIIQSAFRGMQARKTARQIQAARKIQSFLQMALQRRKYIQLRT-AAITLQAYYLMHKTKSQYVRCKKAAVVLQRWYRSHLKVKHQRATYLQ---TRRNIILVQARVRGFIEKKKFHKIKEGTIRIQASYRGYRARQ-WVNKMRAAQVIQAWFRGCRARKEYASVVKATRVIQSHFRRKQQQTWFLKMKFSALTIQRRWRATLTARM-IRYQFLATKNAAKLQAVCVIQKAYRGFKARRKLAQQKAAA---------VIIQKHLRAWQEGRLQFMKYNRTREAVIKLQAFIRGYLVRKKISEEKQKRKLLHFTAAAYHHISAIKIQRAYRTH-LILKLAQNQ-----ISSVLKIQRWFRAKMQRKRFLRDYQRIIQLQRVIRGWLNHRRDAAAIIQRNARRFLACRRKRRFAVGIIKFQALWRGYYWRKTH-------------DTPKTKALRRSLEK-------ANEKSREENKLCNRTAIAIEYLLKYKHISYILEALKHLEVATRLSPLCCESMAQSRAICT--IFVLIRSCNRSVPCMDVIRYAIQVLLNVSKYERTTQAVYEVGNSI-DTLLDLLQMYRGKAGDKVSEKGGSIFTKTCCLLAILSKDSKRALEIRSIPRAVPCIQSLYKLTARKHKMDAERTLVKLKANTFLSGT---SSIPVTPLRIKTVSRIKPDWVLRKDNMQEIVDPLQAILMVMDTLGI 3279 HSP 2 Score: 177.563 bits (449), Expect = 3.174e-41 Identity = 217/841 (25.80%), Postives = 398/841 (47.32%), Query Frame = 0
Query: 1 MYLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVI---HKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQA--FLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHC---------------SATLIQAQWRVW----IQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWR-------------------------------RFKFVQSLAHHLK-------WKRMHQ------SATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTI--QSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHR----------LIRHL-----------AELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
+YL + V IQ +R Y L + E L+++ +Q+ ++ R+R EL R+ K +A ++QS W+ ++ +F LK A+V LQSH R+ + +R+ MK+AA VI ++ + C +RI L+ A +Q ++ + R+ LR S IQS +R++ RK + L+ +T++IQ+ + A K + ++K A +QR +R +R L + +R L + +IQ+ R ++ R+ R++ EA L+ C SA +IQ +R + Q + + Q++ +A+ LQA +G+ R++ + + R+A +Q ++R R F+++ A + WK Q +AT+IQ+ +R + A + + ++A L IQK+YR+ V +A + ++ L + + Q+ WR VRR IQ ++ A +IQS +R + N+ + QA V IQ+ FR + C+++ ++RA A +++QS +RG T R++ L K++ +Q R ++V++DYER RS+ ++QR +R + + + Q + L+ + K+Q+++R R++ + +A+ +I+IQ +R G V+R K+L L+++ + LQ+ + ++ L M +SA IQ +R H+ RH+ ++ Y +M +A+ IQ+ +R K RR R + E AG IQR + +V RK F+ ++ A VIQ+ YR
Sbjct: 1460 VYLEQRAKVVRIQLYYRAYKLGKTEREFYLQKR--AAVLVLQAAFRGMRAR-ELYRQTK---------AACVVQSLWRMKREKLRFLQLKKAAVTLQSHVRKYQQVKRYKEMKKAASVIQTRYREYITCKKAAAAFQRIRLA-----AVVLQSAYRGMKARKEAHILR------------SVIKIQSSYRAYVARKRYKILKDATVKIQAFVKMRQAHKHYCALKEATLYVQRRYRSHRHALQLKK--DYRKLKGACIRIQAVVRGYLVRKQMQRWR-EAAVFLQACYRMRRDRQRYLSIYNSAVVIQKHYRAYKKQLYQRQKFLQVKKAAVCLQAACRGYQARKKLKLEHRAAVKIQTAFRAHAARMKYKALVQASVVIQRWYRACKTGNRQRLDFLRTKAAVISLQAAFRGWKVRKQIQRQCVAATKIQSAFRKFSALKKFRIMKHAVLTIQKHYRASV--IAQEQRQEYVQLRNSVLHLQAVWRGKTVRR----TIQKQHNLATIIQSYYRMHINQQQYRKLRQATVVIQKYFRAY----CMKK------------KQRAIYLKTRAAVLVLQSAYRGMTVRKQLNKLNKAAATIQAAFRSYLVKKDYERLRSAAILVQRHYR-AVICAKCQRQKYLALK-KATIKMQAIYRGVRVRQQLHCMHQAAV-------SIVIQRQYRAFCLGRVRRKKYLELKKSALILQSAFRGMKVRQNLKVMHQSAAKIQSYYRMHKQQKDFRKLLLATRHIQQWFRACKERDVQVHNYMIMKSAALHIQAAFRGMKTRRLVRTMN------ESAG-VIQRRFRTFVKRKHFLSLKTAAIVIQRKYRA 2230 HSP 3 Score: 167.933 bits (424), Expect = 2.688e-38 Identity = 223/853 (26.14%), Postives = 399/853 (46.78%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLE---------ELILERKIN-----------QCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGR------------QAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQ-----HLHERIQFRLL---------------NQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAE-RKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFR----------KFIQRCCLQRCLSERIALR-HEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVR----GWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCV----QRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWR---MHKARR---------------HYRHLTHLAASAEM--AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRG 746
R+ +IQ +WR Y L + L+ +I + IN A IQ +W+ + +R L + L R+++AT+IQ++W+ H R+++ L+ + +Q+ R K + A I +W + K N+R ++ SA IQ + WR R Q + R ++ R+ +A L+QS +R H +RK +LH++ S ++IQ+ +R A++ + + IQ +R Y+ + +L +R +L ++A +QS WRM +R LRF +L+ + TL Q+ R + Q+K YK+M+ +A V+Q + + +I ++ F+ + +A VLQ ++R K + AH L ++K + + +IQ +M QA + Y + A L +Q+ YRSH L + + RKL+ A IQ+ R VR++ QR EAA+ +Q+ +R ++R + V IQ+ +R KF+Q CL + A R ++A+++ E R AA+ IQ+ +R R +Y L ++S+++Q+ R G R D+ R++++V +Q A+R + + K+++ Q ATKIQS +R A ++F + ++ + IQ H+R V QR ++++LR + + LQA+ + +R + A IIQ +R H Q+Y+ + Q+ + IQ +R M K +R YR +T ++ A ATIQ + + ++V+K + R+R A ++Q+HYR
Sbjct: 1222 RAARVIQSAWRNYKLKRELKLSQERDRAARIIQKSAINFLSRRRIMKKRNAAVLIQKYWRRYLARTIFLSLKRTKLLETRSKAATVIQANWRRHSARKKYLQLRYYVIFVQARIRMLKCIAAYKKTVWATVTIQRWLRASKLAK--NDRQRYEILKSSALTIQSAVRRWRARKIQQKIKAALVLQTYFRKWQSSKLAERRGAALLLQSWYRMHRDRKQYLHIKQSVIKIQAWYRCRLARRVYLEQRAKVVRIQLYYRAYKLGKTEREFYLQKRAAVLVLQAAFRGMRARELYRQTKAACVVQSLWRM---KREKLRFL-----QLKKAAVTL-QSHVRKYQQVKRYKEMKKAASVIQTRYREYITCKKAAAAFQRIRLAAVVLQSAYRGMK-ARKEAHILRSVIKIQSSYRAYVARKRYKILKDATVKIQAFVKMRQAHKHYCALKEATLYVQRRYRSHRHALQLKKDYRKLKG-ACIRIQAVVRGYLVRKQMQRW----REAAVFLQACYRMRRDRQRYLSIYNSAVVIQKHYRAYKKQLYQRQKFLQVKKAAVCL--QAACRGYQARKKLKLEHR--AAVKIQTAFRAHAARMKYKALVQASVVIQRWYRACKTGNRQRLDFLRTKAAVISLQAAFRGWKVRKQIQRQCVA------ATKIQSAFRKFSALKKF---------RIMKHAVLTIQKHYRASVIAQEQRQEYVQLRNSVLHLQAVWRGKTVRRTIQKQHNLATIIQSYYRMH------INQQQYRKLRQATVVIQKYFRAYCMKKKQRAIYLKTRAAVLVLQSAYRGMTVRKQLNKLNKAAATIQAAFRSYLVKKDYERLRSAAILVQRHYRA 2032 HSP 4 Score: 136.732 bits (343), Expect = 1.313e-28 Identity = 186/702 (26.50%), Postives = 327/702 (46.58%), Query Frame = 0
Query: 92 ASVVLQSHFRQTKARRRFLTMK---RAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQ----ARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAW--TESRSLAAIL-----IQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRF---------------------ALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRG----CVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
A+ V+QS +R K +R + RAA +I K L ++ + ++ +A IQ YW+ + R FL + E R +AT+IQ+ WR HS RK +L LR+ + +Q+ R + WA IQR R + + ++R ++ +L SA IQS R W +R+ Q++++ +A ++Q +R W Q + R +A++LQ+ + R+Q+ K+S +Q +W R + + + + RIQ +R ++ R+ YL+ + A L +Q +R AR ++ ++ AA +QS WR ++RE+ R +Q + +AA+ +QS R+YQ + +A IQ +R++I C +RI L + A+ ++R A IL IQS +R + R+RY L+ +++ +Q V+ + Y + + +QR +R A+++ + +M+ + A +Q+ +RMR R+ + I SA++IQ H+R QR KFL++++ + LQA + A+++L +A IQ A+R H A KYK + Q+++ IQ +R K R L L A A ++Q + + W VRK+ R A T IQ +R + F+
Sbjct: 1223 AARVIQSAWRNYKLKRELKLSQERDRAARIIQKSAINFLSRRRIMKK------RNAAVLIQKYWRRYLARTIFLSLKRTKLLETRSKAATVIQANWRRHSARKKYLQLRYYVIFVQARIRMLKCIAAYKKTVWATVTIQRWLRASKLAK--NDRQRYEILKSSALTIQSAVRRWRARK--------IQQKIK--AALVLQTYFRKW-QSSKLAERRGAALLLQSWYRMHRDRKQYLHIKQSVIKIQ-AWYRCRLARRV-----YLEQRAKVVRIQLYYRAYKLGKTEREFYLQKRAAVLVLQAAFRGMRARELYR-----QTKAACVVQSLWR---MKREKLRFLQLK-KAAVTLQSHVRKYQQVKRYKEMKKAASVIQTRYREYIT-CKKAAAAFQRIRLAAVVLQSAYRGMKARKEAHILRSVIKIQSSYRAYVARKRYKILKDATVKIQAFVKMRQAHKHYCALKEATLYVQRRYRSHRHALQLKKDYRKLKGACIRIQAVVRGYLVRKQMQRWREAAVFLQACYRMRRDRQRYLSIYN---------SAVVIQKHYRAYKKQLYQRQKFLQVKKAAVCLQAACRGYQARKKLKLEHRAAVKIQTAFRAH------AARMKYKALVQASVVIQRWYRACKTGNRQR-LDFLRTKA--AVISLQAAFRGWKVRKQIQRQCVAATKIQSAFRKFSALKKFR 1871 HSP 5 Score: 87.4261 bits (215), Expect = 1.501e-13 Identity = 128/493 (25.96%), Postives = 225/493 (45.64%), Query Frame = 0
Query: 326 QKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATR-IQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESL-----AATTIQSAWRRNQVRR-----------------------------------------------ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKI-QSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTAL 764
+ R+ARV+Q +WR +K L LK + A R IQ + +R+ ++ +NA + IQKY+R ++AR F + ++ + L AAT IQ+ WRR+ R+ +RQR + +AL IQSA R+++ R ++++I+A + +Q FRK+ Q E R AA+L+QS +R R++Y+ +++S I +Q R + RR Y R+ V IQ +R + L K + E L+ + A + Q+ +R AR + Q +A A ++QS WR ++ +FL+L++ + LQ+ + +R M+++A +IQ +R + + A ++ + +A+ +QS +R KAR+ H+ S IQ S + +V RK++ ++ A IQ + +R A K C +K+ L
Sbjct: 1220 EARAARVIQSAWRNYK----LKRELKLSQERDRAARIIQKSAINFLSRRRIMKKRNAAVLIQKYWRRYLARTIFLSLKRTKLLETRSKAATVIQANWRRHSARKKYLQLRYYVIFVQARIRMLKCIAAYKKTVWATVTIQRWLRASKLAKNDRQR-YEILKSSALTIQSAVRRWRARK-IQQKIKAALVLQTYFRKW--------------------QSSKLAERRG-AALLLQSWYRMHRDRKQYLHIKQSVIKIQAWYRCRLARRVYLEQRAKVVRIQLYYRAYKLGK---TEREFYLQKRAAVLVLQAAFRGMRARELYRQTKA----------ACVVQSLWRMKREKLRFLQLKKAAVTLQSHVRKYQQVKRYKEMKKAASVIQTRYREYITCKKAAA--AFQRIRLAAVVLQSAYRGMKARKE----AHILRSV----IKIQSSYRAYVARKRYKILKDATVKIQAFVK---MRQAHKHYCALKEATL 1659
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Match: gi|984096305|ref|XP_015339278.1| (PREDICTED: abnormal spindle-like microcephaly-associated protein isoform X2 [Marmota marmota marmota]) HSP 1 Score: 245.743 bits (626), Expect = 7.712e-63 Identity = 283/1173 (24.13%), Postives = 545/1173 (46.46%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMH--RSRQELLRRLKLALE----------------LKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQ---------AFLRIMADAQEELRQY-----SATLIQSQWRSHSE----RKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRR-ERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQR--------------------------CLSERIALRHEAQE---RAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRG--------------------------WIVRRDY------------------ERSR-----SSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARI---------------IQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHY--RHLTHLAASAEM---------AGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDFPINEELSKKIEEVRQKVFIANENATEDKKLGNRTALALDRLYRSRDIAHLLMILKDLDVTTRFSANCCDQIMSENDRCVRILLNLLRRCNRSIPHMDIISTILDVFINLAKYEPSRMVLLEAADDVLETLIEVLVIYRDKSVD--------IYTKTFALL-WLLASSNRVKKILTLPLNAKKLLESHKHYHRLHNKQMER---GRRRNNYLPNSFRPSPAQAKPKMPKLSLCPPWQIREDVIRHHKDPFLASEMVLNKLAL 1017
Y+ L +V ++Q +W+ +L ++++ RK ++CA IQS+++MH + R L+R+ L ++ LK + ++QS ++ R++ A++ +QS +R +A++++ + +A +I +W++ H ++ +L+L ++A KIQ ++ R R+ ++ M + +Y +A IQ ++R++ + R+ +L + +Q+ FR ++ M+ AAT+IQ +R YR +++ F L ++ +Q +R +R Q + +L H S +QA +R + K M +A ++Q + + + RR+F S +++ +QR++R + HHL++ ++ ++ +IQ+ +R W R+ Q A + IQ +R H ++FQ ++++ + IQ +R + + +R+ I+ + ++A+VIQ+A++ + R L + +A +RIQ ++ + Q C Q+ C E +++ Q+ R T+ + AAI+IQ H++ + R+ Y+ R + I VQ++ R W R +Y ER+R +S +IQR WR ++ E M +H+ A IQ+ +R R+ F Q Q SA+ ++IQ H R G +R K+L L+++ + LQAL + + +R+++ R AR+ IQRA++ H +++ + SAI IQ +R R+ + ++ + + E+ A + IQ++++ +++RK+ + +T +Q +RGY R K DC KI+ +R + + N E+ KL RT LAL L + ++ +L LK L+V TR S CC+ M+++ +I + L+R CNRS+P M++I + V +N+AKYE + + + ++ + TL+E+L +YR+K D I+TKT LL LL ++NR + + P ++ +K R H ER +++N+ + F P + +L P W +R D I + A +MV++ L +
Sbjct: 1938 YVELHHAVLVLQSAWKGRTLRRQIQ-----RK-HKCAAIIQSYYRMHVQQKRWRLMRKAALLIQMYCRAYRIGREQHRLYLKTKMAVLVLQSAYRGMKVRKRIKKFSKAAITIQSKYRAYRAQKKYAIYRASAIIIQRWYRDIKITNH-QQKEYLNL-KKTAIKIQAVYRGIRVRRHIQHMHFAATLIKAMFKMYQSRVRYHAMRRAAVAIQVRYRAYCQGKIQREKYLATLKAVNTLQASFRGARVRQTLRKMQVAATLIQSCYRRYR------QQMYFNKLKKATKIVQQRYRAVKARNK----QFQRYNQLRH-SVVRLQATFRGMKTRRLLKVMHLAATLIQRRFRTVMMRRKFLSLRKTVIWIQRTYR--AKLCGKKHHLQFLQLRKAVIKIQSSYRGWVVRRQMQEMQRAAVLIQATFRMHRTFVSFQTKKRV----SIIIQQHYRTYRAAKLQRENFIR-QWDSAVVIQAAYKGMKTRQLLREKHRAAIRIQSTYKMYKQYCFYQKLRWATKVLQDRYRANKKKQKALQPNMCKEETNSIQASFQDINIRKQTQKQHEAAIIIQKHFKAFVTRRHYLHFRATVISVQRRYRAIWRRYKAKKYLCKVRAACKIQAWYRCWRARNEYLAVLKAVEIIQGCFYAKRERTRFLKMRASTIIIQRKWRAILSVRMAHEHFLMAKKHRAACLIQAHFRGHKRRQLFLQ-QKSAV--------LIIQRHIRAWEAGKCERIKYLELKKSTVILQALVRGWLERRKILEQRAKARLLHFTAAAYYHLSALRIQRAYKVHMSMKNANK------RVNSAIYIQRWFRAKLERKRFIEKYYSIIKIEHEVQECMNQKNRAASVIQKAVRHFLLRKRQEKFNSRITKLQALWRGYSWRK--KHDCT------------------KIKAIRLSLQMVNREIREEDKLYKRTTLALHYLLTYKHLSAILEALKHLEVVTRLSPRCCEN-MAQSGAISKIFV-LIRSCNRSVPCMEVIRYAVQVLLNVAKYEKTTSAVYD-VENCIHTLLELLQMYREKPGDKVADKGGSIFTKTCCLLAVLLKTTNRASDVRSSPKVVDRIYSIYKLTARKHKINAERILNNQKKNSSIGIPFIPETPIRTRIVSRLK--PDWVLRRDSIEEITNSLQAIQMVMDTLGI 3044 HSP 2 Score: 160.614 bits (405), Expect = 5.863e-36 Identity = 221/914 (24.18%), Postives = 412/914 (45.08%), Query Frame = 0
Query: 7 RSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKR-----------------------NQSATLIQSHWKAHIQREQFCALKTASVVLQSHFRQTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMA-----------DAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHY--------RFVQHLHERIQ----FRLLN--------QSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQ----FESQKRSARVLQRSWRRFKFVQSLAHHL-----------------KWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSH--VAR------------LAFQA---------ERKLESLAATTIQSAWR------------------RNQVRRERQRIIQTRN-----EAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALR--HEAQERAWT-----ESRSLAAILIQSHWRGWTQRQ-----------------------RYIGLRKSSIMVQKQVRGWIV----RRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASAL-------------EE----LKNYSAILI-QSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGY 747
R+ +IQ +WR+Y + EL L + ++ A IQS ++Q++ R++ L +++ N++AT+IQ +W+ + R++F LK SV+LQS R A + A I + W+ L +K +R + S IQ ++ W+ R+ L+I A ++ + ++ SA +IQS +R H E + ++++R + IQ FR + AQK + K + IQ ++ Y ++Q IQ FR + ++A +QSYWRM + +L+ + +QA R QL+ YK+M+ +AI++Q + +I R+ ++ + + VLQ ++R + ++ H L K+ + + ++Q+ +M QAR+ YL + A L IQ++YR+ AR + QA + +L+ AA ++QS +R +N R + ++ Q +N AA +Q+ +R Y+ R L+++ ++IQ FR + +R Q L + ++ + A + A+ + A I +QS +RGW RQ ++ L+ +++++Q+ +R W + R +Y +V V+Q AW+ L ++++ +H+ A IQS +RM + ++ + ++ +AL E+ LK A+L+ QS +RG R + + + I +Q+ +A AQ++ R SA IIQR +R ++ H + ++Y + ++AI IQ+++R + RRH +H+ H AA+ I+ +M+ R ++ +RRA IQ YR Y
Sbjct: 1263 RAARLIQTTWRKYKIK---TELKLYEERDKAARIIQSAVINFLTKQQVKRKINATLVIQKYWRRVLAQRKLLMLKKEKLENVQNKAATVIQGYWRRYSTRKRFLKLKYYSVILQSRIRMIIAVTSYKRYLWATITIQRHWRASLRRKQDQQR--YKRLKSSCLIIQSVFRRWKQRKMQLQIKAAVILQRAFREWHSRRKAKEKSAIVIQSWYRRHRELQKYIYIRSCIVIIQRRFRCFQAQKLYKRKKESVLTIQMYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRMKAWNLYKQIRAAYVLQSYWRMRQDKFRFLKVKK---------IVIRLQAHIRKHQQLQKYKRMKKAAIIIQTHFRAYISARKVLATYQRTRSAVIVLQSAYRGMQARKTFIHILTSIIKIQSYYRAYISRKKFVSLKNATIKLQSVVKMKQARKQYLLLREAVLLIQQWYRTQKMAARKREEYVQIRESCIKLQAFVRGYLVRKQMRLQRKAAVSLQSYFRMRRMRQHYLKTYKAVVVIQNYYRAYKVQVNQRKNFLQVKRAATCLQAVYRGYKVRRLLKQQSLGALKIQTAFRGYSKRVKYQSVLWSVMKIQRWYRAHKSAYDIRTHFLKKKAAVISLQSAYRGWKVRQQIRREHQAAIKIQSTFRMNKAQKQFRLLKSAALIIQQHLRAWTIGKKQRVEYVELHHAVLVLQSAWKGRTLRRQIQR------KHKCAAIIQSYYRMHVQQKRWRLMRKAALLIQMYCRAYRIGREQHRLYLKTKMAVLVLQSAYRGMKVRKRIKKFSKAAITIQSKYRAYRAQKKYAIYRASAIIIQRWYRDIKITNH--QQKEYLNLKKTAIKIQAVYRGIRVRRHIQHM-HFAAT------LIKAMFKMYQSRVRYHAMRRAAVAIQVRYRAY 2147 HSP 3 Score: 133.65 bits (335), Expect = 1.121e-27 Identity = 207/824 (25.12%), Postives = 387/824 (46.97%), Query Frame = 0
Query: 2 YLTLQRSVHIIQRSWRRYSLVQRLEELILERKINQCATQIQSFWKMHRSRQELLRRLKLALELKRNQSATLIQSHWKAHIQREQFCALKTASVVLQSHFR----QTKARRRFLTMKRAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMA------------DAQEELRQYSATLI--QSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVK----GWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATT--IQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKF----IQR----CCLQRCLSERIALRHEAQERAWTESRSLAAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRD----YERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWRGCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHL-------------------AELQKYKVMTQ--SAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFKSDCKIKQTALLPDF 768
YL L+ +V +IQ+ +R + R E ++ I + ++Q+F + + R+++ + K A+ L QS+++ R+ + A VV+Q+++R Q R+ FL +KRAA + ++G ++ L ++ +L + T +GY K + + +M D + + A +I QS +R R+ + ++IQS FR AQK+F +K AA IIQ+ R + + +R+++ L+ + +QS W+ RR Q + +H A +IQ+ +R+ +Q K ++ MR +A+++Q + G Q R + K + VLQ ++R K + + K+ ++A IQ+++R ++A++ Y + + + IQ++YR ++ +++ +L T IQ+ +R +VRR IQ + AA +I++ ++ YQ+R+ +A V IQ +R + IQR L+ + + + R A+ R +AA LIQS +R + Q+ + L+K++ +VQ++ R R Y + R SV +Q +R +RL +++ H AT IQ +R M RR+F ++ + + + Y A L G +FL+LR+ I++Q+ + + +R++ M+ +A +IQ +R HR A+LQ+ + Q SA+ IQ+ ++ K R+ L A IQ + +M+ + ++R A V+Q YR K KQ AL P+
Sbjct: 1692 YLLLREAVLLIQQWYRTQKMAARKREEYVQ--IRESCIKLQAFVRGYLVRKQMRLQRKAAVSL---------QSYFRMRRMRQHYLKTYKAVVVIQNYYRAYKVQVNQRKNFLQVKRAATCLQAVYRGYKVRRLLKQQSLGAL--KIQTAFRGYSKRVKYQSVLWSVMKIQRWYRAHKSAYDIRTHFLKKKAAVISLQSAYRGWKVRQQIRREHQAAIKIQSTFRMNKAQKQFRLLKSAALIIQQHLRAWTIGK--KQRVEYVELHHAVLVLQSAWKGRTLRR---------QIQRKHKCAAIIQSYYRMHVQQKRWRLMRKAALLIQMYCRAYRIGREQHRLYLKTKMAVLVLQSAYRGMKVRKRI------KKFSKAAITIQSKYRAYRAQKKYAIYRASAIIIQRWYRD--IKITNHQQKEYLNLKKTAIKIQAVYRGIRVRRH----IQHMHFAATLIKAMFKMYQSRVRYHAMRRAAVAIQVRYRAYCQGKIQREKYLATLKAVNTLQASFR-GARVRQTLRKMQVAATLIQSCYRRYRQQMYFNKLKKATKIVQQRYRAVKARNKQFQRYNQLRHSVVRLQATFRGMK-TRRL-----LKVMHLAATLIQRRFRTVMMRRKFLSLRKTVIWIQRTYRAKLC-----GKKHHLQFLQLRKAVIKIQSSYRGWVVRRQMQEMQRAAVLIQATFRMHRTFVSFQTKKRVSIIIQQHYRTYRAAKLQRENFIRQWDSAVVIQAAYKGMKTRQ-------LLREKHRAAIRIQSTYKMYKQYCFYQKLRWATKVLQDRYRAN----------KKKQKALQPNM 2450 HSP 4 Score: 123.635 bits (309), Expect = 1.278e-24 Identity = 156/654 (23.85%), Postives = 299/654 (45.72%), Query Frame = 0
Query: 114 RAAGVIHKWWKGCLFQKHLNERIHLSLMNRSATKIQGYWKMWRGRQAFLRIMADAQEELRQYSATLIQSQWRSHSERKAFLHLRHSTLRIQSEFRKWSAQKRFASMKWAATIIQRSWRHYRFVQHLHERIQFRLLNQSATKIQSYWRMWMSRRSYLRFQTEAQEELEHCSATLIQAQWRVWIQLKAYKQMRCSAIVLQAQVKGWIQRRQFESQKRSARVLQRSWRRFKFVQSLAHHLKWKRMHQSATRIQTQWRMWQARQSYLRTQNACLAIQKYYRSHVARLAFQAERKLESLAATTIQSAWRRNQVRRERQRIIQTRNEAALVIQSAWRQYQNRLCLERRIQACVRIQRGFRKFIQRCCLQRCLSERIALRHEAQERAWTESRSL---------AAILIQSHWRGWTQRQRYIGLRKSSIMVQKQVRGWIVRRDYERSRSSVRVIQRAWRRFALIKRLEEQSEMRLRHQWATKIQSLWRMRMARREFAQIQASALEELKNYSAILIQSHWR----GCVQRGKFLRLRRTCIRLQALAKACIAQRRLVSMRESARIIQRAWRRHRLIRHLAELQKYKVMTQSAITIQSLWRMHKARRHYRHLTHLAASAEMAGATIQRSMQMWVVRKKFIRIRRAVTVIQKHYRGYQVRTAFK 754
+AA +I L ++ + +I+ +L+ IQ YW+ ++ L + + E ++ +AT+IQ WR +S RK FL L++ ++ +QS R A + WA IQR WR ++ ++ +++ L S IQS +R W R ++ +Q+KA A++LQ + W RR+ ++++SA V+Q +RR + +Q K+ + IQ ++R +QA++ Y R + + L IQ YY++++ + + AA +Q+A+RR + ++I AA V+QS WR Q++ + + +R+Q RK Q +R ++ A+ + RA+ +R + A I++QS +RG R+ +I + S I +Q R +I R+ + +++ K+QS+ +M+ AR+++ ++ + L LIQ +R +R +++++R +CI+LQA + + ++++ R++A +Q +R R+ +H L+ YK + + IQ+ +R +K + + RK F++++RA T +Q YRGY+VR K
Sbjct: 1289 KAARIIQSAVINFLTKQQVKRKINATLV------IQKYWRRVLAQRKLLMLKKEKLENVQNKAATVIQGYWRRYSTRKRFLKLKYYSVILQSRIRMIIAVTSYKRYLWATITIQRHWRAS--LRRKQDQQRYKRLKSSCLIIQSVFRRWKQR--------------------------KMQLQIKA-------AVILQRAFREWHSRRK--AKEKSAIVIQSWYRRHRELQ------KYIYIRSCIVIIQRRFRCFQAQKLYKRKKESVLTIQMYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRMKAWNLYKQI-----RAAYVLQSYWRMRQDKFRFLKVKKIVIRLQAHIRKHQQLQKYKRM--KKAAIIIQTHFRAYISARKVLATYQRTRSAVIVLQSAYRGMQARKTFIHILTSIIKIQSYYRAYISRKKFVSLKNA-----------------------------TIKLQSVVKMKQARKQYLLLREAVL---------LIQQWYRTQKMAARKREEYVQIRESCIKLQAFVRGYLVRKQMRLQRKAAVSLQSYFRMRRMRQHY--LKTYK----AVVVIQNYYRAYKVQVNQ--------------------------RKNFLQVKRAATCLQAVYRGYKVRRLLK 1816 The following BLAST results are available for this feature:
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 4
BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 22
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BLAST of abnormal spindle-like microcephaly-associated protein homolog vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold1923_size24897:88..6266+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold1923_size24897-snap-gene-0.7 ID=maker-scaffold1923_size24897-snap-gene-0.7|Name=abnormal spindle-like microcephaly-associated protein homolog|organism=Tigriopus kingsejongensis|type=gene|length=6179bp|location=Sequence derived from alignment at scaffold1923_size24897:88..6266+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'abnormal spindle-like microcephaly-associated protein homolog' has the following synonyms
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