BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000005077 (supercontig:LSalAtl2s:LSalAtl2s268:114393:146217:-1 gene:EMLSAG00000005077 transcript:EMLSAT00000005077 description:"maker-LSalAtl2s268-snap-gene-1.30")

HSP 1 Score: 202.216 bits (513), Expect = 1.177e-53
Identity = 95/177 (53.67%), Postives = 130/177 (73.45%), Query Frame = 0

Query: 1539 DLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDR--VVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHP-KVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELAEI 1712
            +L + C D+A+GC YL+ M+++HRDIAARNCLVS L   D   +VKIGDFG AR+IY+D YYRK G  L+PI+WMAPESL D  YT ++DVWS+G++LWEI++ G+  PYP M++LDV  +V N      VP  CP  L  LM +CW++ P  RP+F++C+ E++ELL+Y+DEL  I
Sbjct:  570 NLVRFCLDIARGCLYLTQMRHVHRDIAARNCLVS-LPTSDHTHLVKIGDFGRAREIYRDDYYRKGG--LMPIRWMAPESLEDGVYTHQTDVWSYGIVLWEIISFGK-QPYPGMSHLDVYHYVCNLRKTLDVPLKCPHILYQLMTQCWSYEPINRPSFKECVDEIEELLLYKDELNGI 742          

HSP 2 Score: 145.591 bits (366), Expect = 1.932e-35
Identity = 127/460 (27.61%), Postives = 199/460 (43.26%), Query Frame = 0

Query: 1096 AQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEKEFSVELKDLEPGEIYKIWVEA--RTGSSK-VAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQ--PGHQYQGQIKS-LNPGTQYGLQ-----GVLTFRIGQRT------HTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWNSNNDLVESFELQARIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMES-----NPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV-----QCRD 1528
             +T +  P  P++V   +  P  I V W+ P   NG  + Y VH +           SG        +   ELK L P  +Y IW+ A  RT  SK  + S  I  +TF    L ++  + PRS+   W+SP  +    F   L  L +N N S  +W    S+ +  P   Y  QI + L P T Y ++     G     I  +       + ++WP D   + V T PD PL PG PY+ E  + + V L W+  +  ++ +EL  +       +  +     W + Y D    WP S L+D+ Y F+VRAKNE GWS FS+ +  +NI LIL  K   +S    L+G     + I   +V  +    +++    + +          +++I    V+LN   +S     NP Y +     + +  I     +Q++    +G GAFG V     QC +
Sbjct:   65 TRTEEDIPNNPQHVKGLSKTPSFIFVTWMAPLTFNGS-VAYMVHAKY----------SGITSVYNTTDLEYELKGLNPNSLYVIWISAYLRTNISKGYSSSKRISIKTFKSPPLVQVLQKGPRSLKLHWKSPNSETPVVFHQFL--LYTNQNKSDIRWFPSNSAQRTFPSQNYTTQISTGLYPSTMYIIKVRLFYGEYHINISSQDEQISSLNEFVWPLDDYMLAVNTLPDTPLEPGIPYIFE--NGTYVILIWSGGDMNIDLYELYGK------EINGDGNFYGWBLXYXDVKNFWPPSMLNDSVYKFKVRAKNEHGWSNFSQSSQFININLILQRKK--KSEISILVGSICFSISIFCSIVFYLSFTIIKKTSKNQKS----------ISSISNDLVILNEFRDSFVSANNPLYNL---IGENLSPIKHFSLSQLSFKTKLGSGAFGNVYEGTLQCSE 488          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000005080 (supercontig:LSalAtl2s:LSalAtl2s268:283763:286301:1 gene:EMLSAG00000005080 transcript:EMLSAT00000005080 description:"maker-LSalAtl2s268-augustus-gene-3.12")

HSP 1 Score: 157.147 bits (396), Expect = 5.778e-40
Identity = 78/177 (44.07%), Postives = 104/177 (58.76%), Query Frame = 0

Query: 1539 DLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELAEIPSF 1715
            DL      VAK   YLS  + IHRD+AARN L+   D   ++ K+ DFG ARDI   + Y +     LPI+WMAPESL  N Y+T+SDVWSFG+LLWEI+ LG   PYP  +  DV+ F+  G   + P +C   L NLM  CW   PD RP F+  + + ++LL+ E    ++  F
Sbjct:  398 DLTSYAYQVAKAMEYLSCKKIIHRDLAARNVLI---DYTLQICKVVDFGFARDIMNHSIYERKSDGRLPIRWMAPESLLYNIYSTRSDVWSFGILLWEIVTLGS-TPYPGKSASDVIKFIREGHRLEKPEHCGRELYNLMYYCWVKKPDDRPCFKTLVKDFEKLLLQETNYIDLRIF 570          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000010076 (supercontig:LSalAtl2s:LSalAtl2s663:706586:714919:-1 gene:EMLSAG00000010076 transcript:EMLSAT00000010076 description:"maker-LSalAtl2s663-augustus-gene-7.10")

HSP 1 Score: 150.599 bits (379), Expect = 4.886e-39
Identity = 73/164 (44.51%), Postives = 105/164 (64.02%), Query Frame = 0

Query: 1540 LGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELL 1703
            L  +  DVAKG AYL+D++Y+HRDIA RNCLV+S     R+VK+ DFG+ R +Y++ YYR N + +LP++WM+PESLAD  +T  SDVWS+GVLL+E++  G   P+  ++N  V+  V  G    +P     +L+ L+  CW     +RPT      E+ ELL
Sbjct:  107 LTSMALDVAKGLAYLADLKYVHRDIACRNCLVNS----SRIVKLADFGMTRPMYENDYYRFNRKGMLPVRWMSPESLADGLFTPMSDVWSYGVLLYEMITFGSF-PFQGLSNNQVLEHVKAGNTLSIPSGIKAQLETLLKSCWNIASTKRPT----AAEIAELL 261          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000012370 (supercontig:LSalAtl2s:LSalAtl2s905:198215:201197:-1 gene:EMLSAG00000012370 transcript:EMLSAT00000012370 description:"maker-LSalAtl2s905-augustus-gene-2.8")

HSP 1 Score: 144.821 bits (364), Expect = 1.691e-37
Identity = 72/182 (39.56%), Postives = 105/182 (57.69%), Query Frame = 0

Query: 1523 QVQCRDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLV 1704
             +Q R   RLL L+  ++      ++KG  +LS  + +HRD+AARN L+    A   V+KI DFG+ARD+    YYRK     LPIKWMAPE+   N Y+T+SDVWS+G+LLWEI N G  P     +++ +   +  G     P +CP+   +LM  CW +HP++RP + + +     LL 
Sbjct:   76 HLQKRKNERLL-LSSEEMYSFSNQISKGMNFLSKRKCVHRDLAARNILL----ADKNVIKIADFGMARDVNGKEYYRKRSGGKLPIKWMAPEAFFQNFYSTQSDVWSYGILLWEIANYGEQPYREIFDHITLFKKLDEGYRLSKPSDCPQIFYDLMKYCWKYHPEERPNWENLITLTDSLLA 252          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000003046 (supercontig:LSalAtl2s:LSalAtl2s172:225319:228324:-1 gene:EMLSAG00000003046 transcript:EMLSAT00000003046 description:"maker-LSalAtl2s172-snap-gene-2.21")

HSP 1 Score: 142.895 bits (359), Expect = 8.231e-35
Identity = 78/196 (39.80%), Postives = 115/196 (58.67%), Query Frame = 0

Query: 1534 KLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRD---CLHEVQELLVYEDELAEIPSFCQFNPTSHPNS 1726
            +L L+ L      ++   +YL   +++HRDIAARN LVSS    + VVK+ DFGL+R I  ++YY K  +  LPIKWM+PES+   ++TT SDVW FGV +WEI+ LG   P+  + N DV+  +  G    +P  CP  L ++ML+CW++ P  RPTF++    L E    +  +D L    +  Q +  S P+S
Sbjct:  214 RLDLSHLILYSHQLSTALSYLESKKFVHRDIAARNVLVSS----ENVVKLADFGLSRWIEHNSYY-KASRGKLPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLG-VKPFQGIKNSDVIGKLEKGERLSLPSGCPSHLYSVMLQCWSYEPSNRPTFQELKSVLFETLNEIKIQDSLGGYATPWQGDNNSIPSS 403          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000009561 (supercontig:LSalAtl2s:LSalAtl2s615:613087:620800:1 gene:EMLSAG00000009561 transcript:EMLSAT00000009561 description:"maker-LSalAtl2s615-snap-gene-5.55")

HSP 1 Score: 131.724 bits (330), Expect = 5.614e-31
Identity = 69/178 (38.76%), Postives = 104/178 (58.43%), Query Frame = 0

Query: 1533 LKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELA 1710
            +K++  +   I   +  G  YLSD +Y+HRD+A+RNCL+     +   VKI DFGL++ +    Y+R +    +PI+WM  E++  NKYT +SD+W+FG+LLWEI +L    PY  ++N +V+ F+  G     P N P+ +  +M  CW  +P  RP FR  LH  +EL   E EL 
Sbjct:  736 IKVSHVEQVSISKQICNGMVYLSDRKYVHRDLASRNCLID----QSGTVKIADFGLSQRVSLQEYFRGDVSDNIPIRWMPLEAVLHNKYTIESDIWAFGILLWEIFSLA-LQPYYGLSNEEVIKFLKEGNTLGCPENTPKSIYKIMKSCWNPNPSVRPMFR-ILH--RELETIEKELT 905          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000000181 (supercontig:LSalAtl2s:LSalAtl2s1027:89631:95641:1 gene:EMLSAG00000000181 transcript:EMLSAT00000000181 description:"maker-LSalAtl2s1027-augustus-gene-0.8")

HSP 1 Score: 129.028 bits (323), Expect = 4.498e-30
Identity = 78/213 (36.62%), Postives = 116/213 (54.46%), Query Frame = 0

Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLR-CWAFHPDQRPTF---RDCLH-------EVQELLVYE-------DEL---AEIPSFCQFNPTSHPNS 1726
            L   DL      +  G  YLS  Q +HRD+A RN L+    AK+ V+KI DFGL+R++YK         S +P+KW++ ESL    +T +SD+WSFGV+LWE+  LGR  PYP+M   +++ F+ +G   + P  CP+ +   ++R CW+ +P +RP++   RD          +++EL   E       DEL    E   F   NPT  P+S
Sbjct:  911 LKTEDLLDWAMQITNGMEYLSQKQVVHRDLACRNILI----AKNNVIKICDFGLSRNMYKTYSSSNKKSSPVPVKWLSIESLKYGTFTRRSDIWSFGVVLWEMFTLGRL-PYPNMEYGNLLPFLESGKRMEQPMYCPDSIYYRIMRICWSENPSERPSWIAMRDTFEFMVSNKRDMEELATTEEIRHPNLDELLTNIETNGFIVNNPTYLPDS 1118          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000002397 (supercontig:LSalAtl2s:LSalAtl2s145:1463521:1466086:-1 gene:EMLSAG00000002397 transcript:EMLSAT00000002397 description:"maker-LSalAtl2s145-augustus-gene-15.23")

HSP 1 Score: 118.627 bits (296), Expect = 1.020e-29
Identity = 59/169 (34.91%), Postives = 94/169 (55.62%), Query Frame = 0

Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELL 1703
            +T  D+      +AKG  YL  ++++HRD+AARN L++                      + Y         P+KW++PESL DNKYT+KSDVWSFG+LLWE++  G C PYP +    ++  + +G   + P +C   +  +M  CW+++PD RPTF++ +  ++ LL
Sbjct:   20 ITPQDVIGFSLQIAKGMEYLFGLKFVHRDLAARNVLLT----------------------EGYQ-------FPVKWLSPESLFDNKYTSKSDVWSFGILLWELVXFGGC-PYPGIPPERLVKLLKSGYRMEKPDSCTGEIYEIMTDCWSYNPDARPTFKNLIMRIEILL 158          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000000685 (supercontig:LSalAtl2s:LSalAtl2s1108:63543:67697:1 gene:EMLSAG00000000685 transcript:EMLSAT00000000685 description:"maker-LSalAtl2s1108-augustus-gene-0.17")

HSP 1 Score: 110.538 bits (275), Expect = 2.083e-24
Identity = 63/180 (35.00%), Postives = 96/180 (53.33%), Query Frame = 0

Query: 1524 VQC-RDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLAR--DIYKDAYYRK-NGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFV--PNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLH 1697
            ++C  +P       ++ L +    + +G +YL + + IHRD+AARN LV S +    VVKI DFGL+R   + KD Y    N    LPI W APE +   K+T+ SDVW+F   LWE+ + G   P+  +    ++  +  P+    + PP CP+    +M+ CW+  P +RPTF    H
Sbjct:  223 LECLNEPSSRSSFHVSRLSEFSLQICQGMSYLEEKRLIHRDLAARNILVFSKE----VVKISDFGLSRALGVGKDYYQTNFNANLKLPIAWCAPECINFLKFTSASDVWAFSTALWEMFSYG-FQPWAGLTGKQILDAIDEPHSRRLERPPYCPKDYYRIMMECWSHDPIKRPTFARLYH 397          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000010861 (supercontig:LSalAtl2s:LSalAtl2s721:338828:344970:1 gene:EMLSAG00000010861 transcript:EMLSAT00000010861 description:"maker-LSalAtl2s721-augustus-gene-2.54")

HSP 1 Score: 103.99 bits (258), Expect = 2.205e-22
Identity = 58/170 (34.12%), Postives = 88/170 (51.76%), Query Frame = 0

Query: 1534 KLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDI-YKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVP-NGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTF---RDCLHE 1698
            ++ + ++      +A G  YL   ++IHRD+A RN L+    A    +KIGDFGL R +  KD +Y    ++ +P  W APESL +  ++  SD W F V LWE+ + G+  P+  +N   ++  +   G     P  CP  +  L+L CWA  P  RP F   +D L E
Sbjct:  237 RIPITNIWDFAIQIANGMTYLESKRFIHRDLACRNVLL----ATSSRIKIGDFGLMRALTQKDDFYVMTERNKVPFPWCAPESLKNRLFSHASDTWMFAVTLWEMFSFGQ-EPWLGLNGTQILRKIDVEGERLGQPYACPNYIYRLLLECWAKVPTDRPNFESLKDLLTE 401          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|81910548|sp|Q63132.1|ROS1_RAT (RecName: Full=Proto-oncogene tyrosine-protein kinase ROS; AltName: Full=Proto-oncogene c-Ros; AltName: Full=Proto-oncogene c-Ros-1; AltName: Full=Receptor tyrosine kinase c-ros oncogene 1; AltName: Full=c-Ros receptor tyrosine kinase; Flags: Precursor)

HSP 1 Score: 221.09 bits (562), Expect = 2.295e-56
Identity = 101/167 (60.48%), Postives = 126/167 (75.45%), Query Frame = 0

Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLD-AKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQ 1700
            LTLADL ++C D++KGC YL  M +IHRD+AARNCLVS  D    RVVKIGDFGLAR+IYK  YYRK G+ LLP++WMAPE+L D  +T++SDVWSFG+L+WEI+ LG   PYP  +NLDV+ +V  GG  + P NCP+ L NLM RCWA  PDQRPTF +   ++Q
Sbjct: 2043 LTLADLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYKHDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTLGH-QPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMFRCWAQEPDQRPTFYNIQDQLQ 2208          

HSP 2 Score: 166.777 bits (421), Expect = 7.109e-40
Identity = 331/1614 (20.51%), Postives = 621/1614 (38.48%), Query Frame = 0

Query:   13 LDSVNGNVFWHTGNEIWTVSKCDPS----SSKRIVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNANVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPS--DNSANPCVWQQWTYDIRLESK---SATEKVFQAEETNL-VTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSL-------------PEGPTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAVLLSTDTSLLSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLW-SESLISDLVIDGLGHRLFFTRKDGSQTVIHQMDLEDLSIPVQVVTILEHSTRS----GSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTILLGGRGGRITDLCVQGAPRQMVPQDLDITPL----TVDLDSLKLEEDS---KLVWRALT----GEVTYHLLIQVHGRQYALQTTTSELDLAQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF------HNAVNSSII-VRWNPPKLPNGHIT------------GYQMEINSLDTIIVHPDTLE-QVLVELPSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDV-GAIQTLDFQGPKAV--FSQGGSIFALNLINHVRERVLTQ--AELILHLRVDWISNCIFFVAVSGSDYSIRRFSVD------SGVLSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHA----QCSCFQMDPRSPFYFTLRPNIPEQKASLTLLTHDGSLFATD-NGCECQLMRKIPAWS-----QLSSDGSNLYW----KSHEFVQYLNLQEGQISHFNGSSRNEGVI-----IRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQFRAPCT---NSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIALAQTLDGQ-----PGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEKEFSVELKDLEPGEIYKIWVEA-RTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWNSNNDLVESFELQARIHDSNVTVEDNVTMSNWSVVYADTSPQ---WPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQ-IPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            +DS NG VF+   + I+ V    PS     + RIV    L    +   S R++  +      +   L      ++L        + F   +   L     + +  ++   ++ +      H      E+      V     +Q  P+P +P  +V + FG      S  A ++W+P      A+P  WQ WTY++++ S+     T+       T L V  ++  T +  SVRA S  G   WS P    +L              +G     L+    G+   SD+   N S ++    + + +   G+  +   +   +S    I   A A    L FE     +Y    K+  I R        +++      V  + +D +   L W     S+  + L G S   +L+   W S   +  L +D     L++  +D     ++   L   S     +T     + S     +L YY  +L WI +G +++T   +GQ  S  +     G+     +     + +P +   TP     +V   S ++E  +   +++W        G V Y +    H +  A++  +  +     +  L P     +++   + W K  +   +   P  + S P++ R F      +   N  ++  RWN PK  NG +T            G         ++ V P  +  Q+    P   +   +R   + G  P S +++     +   P ++    + G K++F D+D+ ++  T+ + GA+ T+ +     +  F+QG ++F LNL NH   ++     A  I  + VDWI+  ++F A+  S    + F VD      S     +  +   I    + PL + LY+T ++   +Q+    +S       L+P +++     QCSC   +       T+  + P++       T    ++A D  GC+C  +  +PA        L+ DG  +YW    K    +       G I     + R++ ++     ++PF PD     +   +V        +IL A    L + LP  +   T    + P   + +YY        S+           H  L           E  +    I+ L+PF+ Y I ++++    +  + P E ++L + + G+     PG   ++ AT L   ++ V W      NG   +      +  +      P    + P+ +  S+ +  L  G+ Y + + A  +      +S  +    F     P        S+   W++P    +  F F L   K +      ++    +S   G  Y   I +L P T Y ++ V+ +  G+ + +   P+  K     T    P  PG P ++E    S  +     N + +  + L+ R   SN + + ++    W+ V+  +      W    L    + FR  A N  G+ ++SE    ++  + L   G + + +  ++ +  GI  +  V +  V    L+     K  L +    + ELA   EL  +  G   +N  Y V  +P+++E+E +P   R +++L   +G GAFG+V
Sbjct:  425 VDSYNGYVFYLLRDGIYRVHLPLPSVRDTKAVRIVESGTLKDFAVKPQSKRIIYFNGTMQVFMSTFLDGSAFHRVLPWVPLADVKSFACENNDFLITDGKAIFQQDSLSFNEFIVGCDLSHI-----EEFGFGNLVIFGSSVQSYPLPGHP-QEVSVLFG------SREALIQWKPPILAIGASPSAWQNWTYEVKVSSQDILETTQVFLNISRTVLNVPKLQSSTKYMVSVRASSPKGPGPWSEPSVGTTLVPATEPPFIMAVKEDGLWSKPLSSFGPGEFLSSDV--GNVSDMDWYNNSLYYSDTKGNVYVRPLNGMDISENYHISSIAGA--CALAFEWLGHFLY-WAGKTYVIQRQSVLTGHTDIVTHVKLLVNDMAVDPVGGYLYWTTL-YSVESTRLNGES-SLVLQAQPWLSGKKVIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWSGADATITEFAAWSTSEISQNALMYYSGRLFWI-NGFRIITAQEIGQRTSVSV--SEPGKFNQFTIIQTSLKPLPGNFSSTPTVIPDSVQESSFRIEGHTSSFRILWNEPPAVDWGIVFYSVEFSAHSKFLAIEQQSLPV---FTVEGLEPYALFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSLGRYTRKNEVVVEFRWNKPKHENGVLTKSEIFYHISKQSGTNKSTEDWVSVSVTPPVMSFQLEAMSPGYIVSFQVRVFTSKGPGPFSDIVMSKTSEIKPCPYLI---SLLGNKIEFLDMDQNQVVWTFSLEGAVSTVGYTADDEMGYFAQGDALFLLNLHNHSSSKLFQDVLASDIAVIAVDWIARHLYF-ALKASQDGTQIFDVDLEHKVKSPREVKICKSHTAIISFSMYPLLSRLYWTEVSDLGYQMFYCNISSHTLHHVLQPKASNQHGRRQCSCNVTESELSGAMTVDTSDPDRP--WIYFTKQQEIWAMDLEGCQCWKVIMVPATPGKRIISLTVDGEFIYWITTMKDDTEIYQAKKGSGAILSQVKAPRSKHILAYSSALQPF-PDKAYLSVASNMV------EASILNATNTSLILKLPPVKTNLTWHGITTPTSTYLVYYMEANRANSSD---------RKHNML-----------ESQENVARIEGLQPFSTYVIQIAVK----NYYSDPLEHLSLGKEIQGKTKSGVPGAVCHINATVLSDTSLLVFWTESHKPNGPKELVRYQLVMSYLAPIPETPLRQDEFPSAR-LSLLVTKLSGGQQYVLKILACHSEEMWCTESHPVSVNMFDTPEKPSALVPENTSLLLDWKAPSNANLTRFWFELQKWKYS------EFYHVKASCSQGPVYVCNIANLQPYTPYNIRVVVVYTTGENSSSI--PESFK-----TKAGVPSKPGIPKLLEGSKNSIQWEKAEDNGNRLMYYTLEVRKSISNDSRDQSL---RWTAVFNGSCSSICTWRSKNLK-GTFQFRAVASNAIGFGEYSE----ISEDITLVEDGFWITETSFILTIIVGIFLVATVPLTFVWHRSLKNHKATKEGLSVLNDNDQELA---ELRGLAAGVGLANACYAVHTLPTQEEIESLPAFPREKLSLRLLLGSGAFGEV 1951          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|125677|sp|P00529.1|ROS_AVISU (RecName: Full=Tyrosine-protein kinase transforming protein ros)

HSP 1 Score: 204.527 bits (519), Expect = 4.377e-56
Identity = 92/162 (56.79%), Postives = 120/162 (74.07%), Query Frame = 0

Query: 1543 ICCDVAKGCAYLSDMQYIHRDIAARNCLVSS--LDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
            IC D+ KGC YL  M++IHRD+AARNCLVS     +  RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D  +T  SDVW+FGVL+WE + LG+  PYP ++N++V+  V +GG  + P NCP+ +++LM RCWA  P  RPTF    H++QE+
Sbjct:  212 ICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQ-QPYPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEI 372          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|81911840|sp|Q78DX7.1|ROS1_MOUSE (RecName: Full=Proto-oncogene tyrosine-protein kinase ROS; AltName: Full=Proto-oncogene c-Ros; AltName: Full=Proto-oncogene c-Ros-1; AltName: Full=Receptor tyrosine kinase c-ros oncogene 1; AltName: Full=c-Ros receptor tyrosine kinase; Flags: Precursor)

HSP 1 Score: 217.624 bits (553), Expect = 2.128e-55
Identity = 99/167 (59.28%), Postives = 127/167 (76.05%), Query Frame = 0

Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLD-AKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQ 1700
            LTL DL ++C D++KGC YL  M +IHRD+AARNCLVS  D    RVVKIGDFGLAR+IYK+ YYRK G+ LLP++WMAPE+L D  +T++SDVWSFG+L+WEI+ LG   PYP  +NLDV+ +V  GG  + P NCP+ L NLM +CWA  PDQRPTF +  +++Q
Sbjct: 2044 LTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYKNDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTLGH-QPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQ 2209          

HSP 2 Score: 173.326 bits (438), Expect = 7.649e-42
Identity = 340/1642 (20.71%), Postives = 623/1642 (37.94%), Query Frame = 0

Query:   13 LDSVNGNVFWHTGNEIWTVSKCDPSS----SKRIVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHD-HAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNANVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSDNS--ANPCVWQQWTYDIRLESKSATE--KVFQAEETNLVTC--VEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAVLLSTDTSLLSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPA-RGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFFT--------RKDGSQTVIHQ--------------MDLED------------LSIPVQVV--------TILEHSTRSGS------LNYYHDKLQWIQDGNQLVTFDLVGQSWSTILLGGRGGRITDLCVQGAPRQMVPQDLDITPLT----VDLDSLKLEEDS---KLVWRALT----GEVTYHLLIQVHGRQYALQTTTSELDLAQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF------HNAVNSSII-VRWNPPKLPNGHITGYQMEI-------------NSLDTIIVHPDTLEQVLVELPSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDV-GAIQTLDF--QGPKAVFSQGGSIFALNLINHVRERVLTQAELILHLRV---DWISNCIFFVAVSGSDYSIRRFSVD--------SGVLSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTH----AQCSCFQMDPRSPFYFTLRPNIPEQKASLTLLTHDGSLFATD-NGCECQLMRKIPAWS-----QLSSDGSNLYW--KSHEFVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQFRAPCT---NSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIALAQTLDGQ-----PGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEKEFSVELKDLEPGEIYKIWVEA-RTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWNSNNDLVESFELQARIHDSNVTVEDNVTMSNWSVVYADTSPQ---WPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQ-IPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            +DS NG +F+   + I+ V+   PS     + RIV    L    +   S R++  + +  +L M   +D     ++L        + F   +   L     + +  ++   ++ +      H      E+      V     +Q  P+P +P  +V + FG      S  A ++W P   +  A+P  WQ WTY++++ S+   E  +VF      ++    ++  T +  SVRA S  G   WS P    +L        +  +++  ++   L                  C  G    LS+D   +S                  + ++ S+Y    K +  +R        E   IP+  G  AL  + L   L W      I   S+       +  + L    L++D+ +D +G  L++T        R +G  +++ Q              +DL D            + +   V+        TI E +  S S      L YY  +L WI +G +++T   +GQ  S  +      +     +     + +P +   TP      V   S ++E  +   +++W        G V Y +    H +   ++  +  +     +  L P T   +++   + W K  +   +   P  + S P++ R F      +   N  ++  RWN PK  NG +T +++               + +   ++ P    Q+    P   +   +R   + G  P S +++     +   P ++    + G K+ F D+D+ ++  T+ + G + T+ +        F+QG ++F LNL NH   + L Q  L+  +RV   DWI+  ++F A+  S    + F+VD          V +   HT   I    + PL + LY+T ++    Q+    +S       L+P +++    +QCSC   +       T+  + P++       T    ++A D  GC+C  +  +P         L+ DG  +YW  K+ +  Q    ++G  +  +    +    I  +    Q  P K  L  +      TIL A    L + LP  +   T    + P   + IYY        S+           H  L           E  +    I+ L+PF+ Y I ++++    +  + P E + L + + GQ     PG   ++ AT L   ++ V W      NG          +  +      P    + P+ K  S+ +  L  G++Y + V A         +S  +    F     P        S+   W++     +  F F L   K N      ++    +S   G  Y   I  L P T Y ++ V+ +  G+ + +   P+  K     T    P  PG P ++E    S  +     N   +  + L+ R   SN   +     S W VV+  +      W    L    + FR  A NE G  ++SE    ++  + L   G++ + +  ++ +  GI  +  V +  V    L+     K  L +    + ELA   EL  +  G   +N  Y V  +P+++E+E++P   R +++L   +G GAFG+V
Sbjct:  426 VDSYNGYLFYLLRDGIYRVNLPLPSGRDTKAVRIVESGTLKDFAVKPQSKRIIYFN-DTMQLFMSTFLDGSAFHRVLPWVPLVTVKSFACENNDFLITDGKAIFQQDSLSFNEFIVGCDLSHI-----EEFGFGNLVIFGSSVQSYPLPGHP-QEVSVLFG------SREALIQWTPPALAIGASPSAWQNWTYEVKVYSQDILEITQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVGTTLVPATEPPFIMAVKEDGLWSKPL------------------CSFGPGEFLSSDVGNVSD----------------MDWYNNSLYYSDTKGNVYVRPLNGMDISENYHIPSIVGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIVTHVKL----LVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWSGGDATITEFAAWSTSEISQNALMYYSGRLFWI-NGFRIITAQEIGQRTSVSV--SEPAKFNQFTIIQTSLKPLPGNFSSTPKVIPDPVQESSFRIEGHTSSFQILWNEPPAVDWGIVFYSVEFSTHSKFLIIEQQSLPIF---TVEGLEPYTLFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSSGRYTKKNEVVVEFRWNKPKHENGVLTKFEIFYHISKQSGTNRSTEDWMSASVIPPVMSFQLEAVSPEYTVAFQVRVFTSKGPGPFSDIVMSKTSEIKPCPYLI---SLLGNKIVFLDMDQNQVLWTFSLEGDVSTVGYTTDDEMGYFAQGDTLFLLNLRNHSSSK-LFQDALVSDIRVIAVDWIARHLYF-ALKASQNGTQIFNVDLEHKVKSPREVKTCKAHTT--IISFSIYPLLSRLYWTEVSDLGHQMFYCNISNHTSQHVLQPKASNQHGRSQCSCNVTESELSGAMTVDTSDPDRP--WIYFTKRQEIWAMDLEGCQCWKVIMVPTIPGKRIISLTVDGEFIYWIMKTKDDAQIYQAKKGSGAILSQVKASRSKHILAYSSALQPFPDKAYLSLASDMVEATILYATNTSLTLKLPPVKTNLTWHGITHPTSTYLIYYMEANRANSSD---------RRHKML-----------ESQENVARIEGLQPFSMYMIQIAVK----NYYSEPLEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHKPNGPKESVRYQLVMSYLAPIPETPLRQGEFPSAK-LSLLITKLSGGQLYVMKVLACHPEEMWCTESHPVSVNMFDTPEKPSALVPENTSLQLDWKARSNVNLTGFWFELQKWKYN------EFYHVKASCSQGPVYVCNITDLQPYTSYNIRVVVVYTTGENSSSI--PESFK-----TKAGVPSKPGIPKLLEGSKNSIQWEKAEDNGSRLMYYTLEVRKGISN---DSQNQSSRWKVVFNGSCSSICTWRSKNL-KGTFQFRAVAANEIGLGEYSE----ISEDITLVEDGVWITETSFILTIIVGIFLVATVPLTFVWHRSLKSHKASKEGLSVLNDNDKELA---ELRGLAAGVGLANACYAVHTVPTQEEIENLPAFPREKLSLRLLLGSGAFGEV 1952          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|126302596|sp|P08922.3|ROS1_HUMAN (RecName: Full=Proto-oncogene tyrosine-protein kinase ROS; AltName: Full=Proto-oncogene c-Ros; AltName: Full=Proto-oncogene c-Ros-1; AltName: Full=Receptor tyrosine kinase c-ros oncogene 1; AltName: Full=c-Ros receptor tyrosine kinase; Flags: Precursor)

HSP 1 Score: 212.231 bits (539), Expect = 1.119e-53
Identity = 98/161 (60.87%), Postives = 120/161 (74.53%), Query Frame = 0

Query: 1544 CCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKD-RVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELL 1703
            C D++KGC YL  M +IHRD+AARNCLVS  D    R+VKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D  +TT+SDVWSFG+L+WEI+ LG   PYP  +NLDV+ +V  GG  + P NCP+ L NLM +CWA  PDQRPTF    H +Q+ L
Sbjct: 2060 CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGH-QPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTF----HRIQDQL 2215          

HSP 2 Score: 154.066 bits (388), Expect = 5.879e-36
Identity = 299/1441 (20.75%), Postives = 559/1441 (38.79%), Query Frame = 0

Query:  191 PCVWQQWTYDIRLESKSATE--KVFQAEETNLVTC--VEHGTVFNASVRAVSEGGKSEWSIPVSAQSL-PEGPTDLVLT------WIRK------GQVFQSDLLGTNHSRVELPFKARHVACRSGDAVLLSTDTSLLSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFFTRKDGSQTVIHQMDLEDLSIPVQVVTILEHSTRS----GSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTILLGGRGGRITDLCVQGAPRQMVPQDLDITPL----TVDLDSLKLEEDS---KLVWRALT----GEVTYHLLIQVHGR-----QYALQTTTSELDLAQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF----HNAVNSSIIV---RWNPPKLPNGHITGYQMEINSLDTIIVHPDTLEQVLVEL-------------PSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDV-----GAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVLTQAELILHLRV---DWISNCIFFVAVSGSDYSIRRFSVD------SGVLSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQ-----CSC----FQMDPRSPFYFTLRPNIPEQKASLTLLTHDGSLFATD-NGCECQLMRKIPAW------SQLSSDGSNLYW--KSHEFVQYLNLQEGQISHFNGSSRNEGVIIRP---FCPDCQMTPIKQCLVPSLVEQRV--TILEAGEDWLRVSLPQFRAPCT---NSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQK--GKPSQQTIPTELIALAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEKEFSVELKDLEPGEIYKIWVEA-RTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWNSNNDLVESFELQARIHDSNVTVEDNVTMSNWSVVYADTSPQ---WPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSA---LGIQRHRELELATIHELPVMLNGGMESNPTYGVQ-IPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            P  WQ WTY++++ ++   E   +F      ++    ++    +  SVRA S      WS P    +L P      ++       W +       G+   SD+   N S ++    + + +   GD  +   + + +S    +   A A    L FE     +Y    K+  I R        +++      V  + +DS+   L W     S+  + L G S   +     +S   +  L +D     L++  +D     ++   L   S     +T     + S     +L YY  +L WI +G +++T   +GQ  S  +L     R     +     + +P +   TP     +V   S ++E ++   +++W        G V Y +    H +     Q++L   T E         L P     +++   + W K P+   +L  P  + S P++ R F        N + +V   RWN PK  NG +T +++  N  +  I +    + + V +             P   +   +R   + G  P + ++      +   P ++    + G K+ F D+D+ ++  T+           T D +     +++G S+F L+L N      L Q  L+  + V   DWIS  ++F A+  S   ++ F VD            + +    I    + PL + LY+T +++  +Q+    +      + L+PT+T+ Q     CSC    F++         +  +    +  L        ++A D  GC+C  +  +PA         L+ DG  +YW   + +  Q    ++G     NG+  ++   +R          M P       SL    V  TIL A    L + LP  +   T    + P   + +YY  +  + +S          S      L+ Q  I          LI+DL+PF+ Y I ++++     P +   P + I   +T +G P   + +  T     ++ ++W      NG          +  +      P    + P  +  ++ +  L  G IY + V A  +      +S  +  + F+    P        S+ F W++P    +  F   L   K N      ++    +S   G  Y   I +L P T Y ++ V+ ++ G+ + +   P+  K     T    P  PG P ++E    S  +     N   +  + L+ R   SN     N+    W + +  +      W    L    + FRV A N  G+ ++S     ++  +IL     +   +  ++ +   IVGI  V+ + +  ++ RR  ++KSA   + +  + + ELA   EL  +  G   +N  Y +  +P+++E+E++P   R ++TL   +G GAFG+V
Sbjct:  602 PSAWQNWTYEVKVSTQDPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSEPSVGTTLVPASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDI--GNVSDMDWYNNSLYYSDTKGDVFVWLLNGTDISENYHLPSIAGA--GALAFEWLGHFLY-WAGKTYVIQRQSVLTGHTDIVTHVKLLVNDMVVDSVGGYLYWTTL-YSVESTRLNGESSLVLQTQPWFSGKKVIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQSTGDTTITEFAAWSTSEISQNALMYYSGRLFWI-NGFRIITTQEIGQKTSVSVL--EPARFNQFTIIQTSLKPLPGNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSKFLASEQHSLPVFTVE--------GLEPYALFNLSVTPYTYWGKGPKTSLSLRAPETVPSAPENPRIFILPSGKCCNKNEVVVEFRWNKPKHENGVLTKFEIFYNISNQSITNKTCEDWIAVNVTPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGPYADVVKSTTSEINPFPHLIT---LLGNKIVFLDMDQNQVVWTFSAERVISAVCYTADNE--MGYYAEGDSLFLLHLHNRSSSE-LFQDSLVFDITVITIDWISRHLYF-ALKESQNGMQVFDVDLEHKVKYPREVKIHNRNSTIISFSVYPLLSRLYWTEVSNFGYQMFYYSIISHTLHRILQPTATNQQNKRNQCSCNVTEFELSG------AMAIDTSNLEKPLIYFAKAQEIWAMDLEGCQCWRVITVPAMLAGKTLVSLTVDGDLIYWIITAKDSTQIYQAKKG-----NGAIVSQVKALRSRHILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTWYGITSPTPTYLVYYAEVNDRKNS----------SDLKYRILEFQDSI---------ALIEDLQPFSTYMIQIAVKNYYSDPLEHLPPGKEI-WGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISHLALIPETPLRQSEFPNGR-LTLLVTRLSGGNIYVLKVLACHSEEMWCTESHPVTVEMFNTPEKPYSLVPENTSLQFNWKAPLNVNLIRFWVELQKWKYN------EFYHVKTSCSQGPAYVCNITNLQPYTSYNVRVVVVYKTGENSTSL--PESFK-----TKAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEIRKSTSNNLQNQNL---RWKMTFNGSCSSVCTWKSKNLK-GIFQFRVVAANNLGFGEYSG----ISENIILVGDDFWIPETSFILTI---IVGIFLVVTIPLTFVWHRRLKNQKSAKEGVTVLINEDKELA---ELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEV 1959          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|112856|sp|P20806.1|7LESS_DROVI (RecName: Full=Protein sevenless)

HSP 1 Score: 211.46 bits (537), Expect = 1.837e-53
Identity = 104/225 (46.22%), Postives = 142/225 (63.11%), Query Frame = 0

Query: 1532 LLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDA--KDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL--------LVYEDELAEIPSFCQFNPTSH------PNSVSMH-NSRDTWKTS 1739
            L KL L +L  +C DVA GC+Y+ DM ++HRD+A RNCLVS   A    R+VKIGDFGLARDIYK  YYRK G+ LLP++WMA ESL D  ++T+SDVW+FGVL WEI  LG+  PY   NN +V+  V  GG  + P  CPE+L  L+L+CW   P +RP+F+ CL  +Q L        ++  DE   + + C F P +       P  +++H +++DT  T+
Sbjct: 2324 LSKLQLPELLSMCLDVANGCSYMEDMHFVHRDLACRNCLVSDGAAIGGRRIVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMALESLVDGLFSTQSDVWAFGVLCWEIFTLGQ-QPYAARNNFEVLAHVKEGGRLQQPERCPEKLYALLLQCWRSEPWERPSFKRCLSTLQALSSDLRRTEMLATDETPLVSALCAFKPDAKVRFDDAPQRLTLHLDAKDTVSTT 2547          

HSP 2 Score: 98.9821 bits (245), Expect = 2.992e-19
Identity = 235/1101 (21.34%), Postives = 414/1101 (37.60%), Query Frame = 0

Query:  516 DLDITPLTVDLDSLKLEE-----DSKLVWR-ALTG---EVTYHLLIQVHGRQYALQTTTSELDLAQEIASLTPNTE----VRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQMEINSLDTIIVHPDTL-EQVLVELPSQQLHID--LRCQNNAGLSPASTLLIQNRFVL------PSLPQILIYQGIQGGKLDFYDLDRRRIRATYDVGAIQTLD-FQGPKAVFSQGGSIFALNLINHVRERV-----LTQAELILHLRVDWISNCIFFVAVSGSD-----YSIRRFSVDSGVLSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQCSCFQMDPRS-PFYFTLRPNIPEQKASLTLLTHDGSL--------FATDNGCECQLMRKIPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAG-----EDWLRVSLPQFRAP--CTNSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIALA----QTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEKEFSVE-LKDLEPGEIYKIWVEARTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW-----NSNNDLVESFE-LQARIHDSNVTVEDNVTMS--NWSVVYADTSPQW-------PISGLSDAAY-----LFRVRAKNE-FGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELEL---------ATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            D  + PL V  DS+ ++E     D ++ W+ A +G    V Y LL++ HG +  +      L+L    A +T   +    +R+++   + W         L TP    + P+ LR F          A N S ++RW+ P+   G     Q  I+      +H + L  Q  +E   + L  +   R Q  A ++            L       S+P++L       G+LD     R+++   +    ++ L   QG + +      +    L++HV  +        +AE +L L VDW+   +++  +  +D     YS+     D  +L          + +   P    L          QL  L+  L  R  +L+  S  A  S    +  + P +     +      +L L+ H G L          T +    QL        QL+ D   LY   +  V+    +  Q+        +E  ++R +  + Q  P ++CL   L+      LE+      E    + LP   A   C   +P + + +           EL S+       H +  L L               I  L+P+  Y   L  Q G   QQ +  E + L      T    P  P N +  AL P  +E++WL P       + Y +H++L    T  +      Q+   +   V+ L  L+P  +Y++W++A    SK   S  +  ++++ +   ++       +T  W   P  A+ +       L+  L  +             G+  Q ++  L P T+Y  +  L +        Y  P        ET  DAP  PG+P  +E ++     ++W     N +  L+ + E LQAR  +         T+S   W+        QW        +S +    +     LFRVRA+N   GW  +SED+  +    +   K       G+L+     I+    ++   VL + L R   K+      RHR  +L         + +  L          + T+ + + S+ ++  +P++  N++TL+ F+G GAFG+V
Sbjct: 1221 DEGVRPLAVPPDSVHIDEGGHWNDFRVRWQPAASGGNHSVCYKLLLE-HGSERLI-----TLELLTPFARITQLAQAPLGLRISITPHTAWRAGSTTRVQLDTPVAAPTQPRRLRVFVERQAAPLQLAPNVSALLRWDVPEEHAGS-QSLQYRISCWRGSELHSELLLNQSTLEARVEHLQPEETYRFQVQAHVAATGLAAGATSHALHVSPEVQSVPRLLYANAEHIGELDLDTGHRKQL--VHTASPVEHLVVLQGEQRLLWVNEHV---ELLSHVPGKAPAKLARMRAE-VLALTVDWVQRIVYWAELDAADGGCVIYSLDLCRFDGRILQG--------ERLWSTPRGQLLRDLVALPHARQLVWLQHDLDSRNATLQGRSL-ANGSALTFEGVTLPLWRLFEGSQEPLAETLNLVDHLGRLCVYHVARQLCTSSALRAQLNLLNDDIGQLAQDPGYLYALRNGSVRAYGRRRQQLEFLLELQPDEVRLLRAY--NYQAYPSRRCL---LLPTTAAALESTPSSCEETQCSLQLPALSAAPDCPLPVPGLNYQLNLSSSSRSAQLELRSL-------HSAAGLTLN--------------ISQLQPYQAY--ELRAQVGSYYQQQLGQEPLQLPVLTLHTAAATPSAPRNFSGRALSPSELELSWLAPLELRSASVYYTLHWQLQLEDTEEQSQEQPAQEQRVETAGVQRLTGLQPARLYQVWLQAHATPSKYNSSGRLLIRSYAPLPPLQLIELNAYGMTLAWPGTP-DALSSLTLECQSLREQLQFN-----------VAGNHTQMRLAPLQPKTRYSCRLALAYAATPGAPIYFGPSHE----YETLGDAPSAPGRPQ-LEHIAGEIFRVSWTPALDNGSPILLYNLEALQARRTNRRRRRRRETTLSLLPWAEEPLVIEDQWLDFCNTTELSCIVRELHTRRLLLFRVRARNRPHGWGPYSEDSERIAEPFVSPEK------RGSLV---LAIIAPAAIVSSCVLALVLVRKLQKR------RHRAKKLLQQSRPSIWSNLSALQTQQQLLAARSRTFSMSL-SDADIALLPQINWNRLTLLRFLGSGAFGEV 2238          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|14424434|sp|P13368.2|7LESS_DROME (RecName: Full=Protein sevenless)

HSP 1 Score: 202.601 bits (514), Expect = 1.084e-50
Identity = 91/172 (52.91%), Postives = 121/172 (70.35%), Query Frame = 0

Query: 1527 RDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDA---KDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDC 1695
            ++P+    L+L++L  +C DVA GC+YL DM ++HRD+A RNCLV+       + R VKIGDFGLARDIYK  YYRK G+ LLP++WM+PESL D  +TT+SDVW+FGVL WEI+ LG+  PY   NN +V+  V  GG  + PP C E+L +L+L CW   P +RP+FR C
Sbjct: 2307 QEPQPTAGLSLSELLAMCIDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQ-QPYAARNNFEVLAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRC 2477          

HSP 2 Score: 97.8265 bits (242), Expect = 7.590e-19
Identity = 116/498 (23.29%), Postives = 204/498 (40.96%), Query Frame = 0

Query: 1063 IKDLEPFTRY---GIYLSLQKGK---PSQQTIPTELIALAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHY--ELHKVITTSRIPSGHRQKPTEKEFSVELKDLEPGEIYKIWVEARTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWNS---NNDLVESFELQARIHDSNVTVEDNVTMSN---------WSVVYADTSPQW-------PISGL-----SDAAYLFRVRAKN-EFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALG---IQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            + DL PFTRY   GI  S  + K   P+    P EL+  + T    P PP N +   L P  +EV+WLPP+    + + Y +H+  EL       R      ++  E   +  L  ++PG  Y +WV+A    +K   S  +  ++F+ +   ++    P S++  W   P   + + Q     L+   +A Q      L     G+  +  ++ L P T+Y  + +L +        Y         + ET  DAP  PG+P  +E ++E    + W +   N   +  + L+A    S++         N         W+        QW        +S +     S    LFRVRA++ E GW  +SE++  +    +   K       G+L+     I+    ++   VL + L R   K+       +Q+ R    + +  L          N  +   + S+ ++  +P++  +Q+ L+ F+G GAFG+V
Sbjct: 1757 LTDLLPFTRYRVSGILSSFYQKKLALPTLVLAPLELLTASAT----PSPPRNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGENVQDRREWEAHERRLETAGTHRLTGIKPGSGYSLWVQAHATPTKSNSSERLHVRSFAELPELQLLELGPYSLSLTWAGTP-DPLGSLQ-----LECRSSAEQ------LRRNVAGNHTKMVVEPLQPRTRYQCRLLLGYAATPGAPLY----HGTAEVYETLGDAPSQPGKPQ-LEHIAEEVFRVTWTAARGNGAPIALYNLEALQARSDIRRRRRRRRRNSGGSLEQLPWAEEPVVVEDQWLDFCNTTELSCIVKSLHSSRLLLFRVRARSLEHGWGPYSEESERVAEPFVSPEK------RGSLV---LAIIAPAAIVSSCVLALVLVRKVQKRRLRAKKLLQQSRPSIWSNLSTLQTQQQLMAVRNRAFSTTL-SDADIALLPQINWSQLKLLRFLGSGAFGEV 2223          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|57013873|sp|P08941.3|ROS1_CHICK (RecName: Full=Proto-oncogene tyrosine-protein kinase ROS; AltName: Full=Proto-oncogene c-Ros; AltName: Full=Proto-oncogene c-Ros-1; AltName: Full=Receptor tyrosine kinase c-ros oncogene 1; AltName: Full=c-Ros receptor tyrosine kinase; Flags: Precursor)

HSP 1 Score: 201.445 bits (511), Expect = 2.128e-50
Identity = 90/162 (55.56%), Postives = 119/162 (73.46%), Query Frame = 0

Query: 1543 ICCDVAKGCAYLSDMQYIHRDIAARNCLVSS--LDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
            IC D+ KGC YL  M++IHRD+AARNCLVS     +  RVVKIGDFGLARDIYK+ YYRK G+ L+ ++WMAPESL D  +T  SDVW+FGVL+WE + LG+  PYP ++N++V+  V +GG  + P NCP+ +++LM RCWA  P  RPTF    H++QE+
Sbjct: 2075 ICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYKNDYYRKRGEGLINVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQ-QPYPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEI 2235          

HSP 2 Score: 160.229 bits (404), Expect = 8.317e-38
Identity = 333/1624 (20.50%), Postives = 602/1624 (37.07%), Query Frame = 0

Query:   37 SSSKRIVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNAN--VLHQLMGDNRSGHFQS-------SFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSDNS--ANPCVWQQWTYDIRLESKSATEKVFQAEE--------TNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAVLLSTDTSLLSAQGQILFKANAEISG-----------LLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDL-WSESLISDLVIDGLGHRLFFTRKDGSQTVIHQMDLEDLSIPVQVVTILEHSTRS----GSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTILLGGRGGRITDLCVQGAPRQMVPQDLDITPL----TVDLDSLKLEEDSK---LVWRALTGEVTYHLLIQVHGRQYALQTTTSELDL--------AQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF------HNAVNSSII-VRWNPPKLPNGHITGYQM------EINSLDTII------VHPDTL-EQVLVELPSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRI-------RATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVLTQAEL--ILHLRVDWIS-------------NCIFFVAVSGSDYSIRRFSVDSGVLSNVTHTQDDIQHM-------ELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQCSCFQMDPRSPFYFTLRPNIPEQKASLTLLTHDGSLFATD-NGCECQLMRKIPAW-----SQLSSDGSNLYW--KSHEFVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQFRAP--CTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIALAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKF--IIYDVHYELHKV-----ITTSRIPSGHRQKPTEKEFSVELKDLEPG--EIYKIWVEARTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFI--WRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWNSNNDLVESFELQARIHDSNVTVEDNVTMSNWSVVY---ADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFL-----------RRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQ-IPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            S++  +V    L    I+F S RL+  + + ++  +   +D      L         P   M     F Y D+ +       V H+ +    S  F          + E       +F+    QP P+P  P L V + FG      S  A + W P + +   +   WQ WTYD+++ S+S  E+ +             NLV+  E    +  SVRAVS  G+  WS P    +  E   +  +  +    +++  L          P   R+++        L    S+   Q   + K                  L F+   + +Y    K++ I R        +V+      VK L +DS+   L W    T  V S+        IL+  L +S   +  L +D     L++  +DG    ++++ +   S    +VT +   + S     +L YY  +L WI +  + +T   + QS S               +     + +P +   TP     +V   S K++ +S    ++W A T      +   V      ++T  SE  L        + ++  L P T    ++   + W K+P     L  P  + S P + R +      H      ++ +RW+ P+  NG +T +++      E  + DT++      V P  L   +  E P   +   ++   + G  P S +  +N   +  +P ++ +      KL   D+D           R   D+      D    K  +    S+F LN+ +    ++     L  +  + VDWI+               +FF+ +     S++  ++  G  ++   +      +       ELD  +   YY  L +  + +        G     +    +  C+  + +   P    +      +K  L  +     ++A+D + C C  + KIP++       L+ D   +YW  +  E+ +     +    H      N  + I  +    Q  P K+CL P L  ++ TIL+       +SLP       C + S P   + +++  I S           E+ + H S  L+  + IQ P       +I +L+PF+ Y I ++++    +Q  +     A++ TL G P   +++    L   TI ++W  P   NG    I Y +   L  +     +  S  P+G          S  + DL+ G   ++K+ +      +  ++S  + A+TF     P  +   PR+ +F   WR+P      +F F L   ++    S +  P   ++   G  Y   +    P   Y ++  + +  G ++        S     +T    P  PG P   E    S  +     N   +  + L++R    N     N   S W VVY    D    W    L +  + FR  A N  G  ++S+           +SK +  +           IV +IG +V+ + II L           R+P      + ++  +EL      +L  M      +N  Y V  +PS+ E+E +P   R+++ L   +G GAFG+V
Sbjct:  453 SAASLVVKSHTLRDFMINFQSKRLIFFN-KTEQAFVSGFLDGSEFHTL-----RAHVPLDDMES---FVYEDNIFTVTDGRAVFHEEISQVGSSSFNEYVVDCSLEYPEYFGFGNLLFYAASTQPYPLPTLPRL-VTVLFG------SDQAVISWSPPEYTIGTSRSAWQNWTYDVKVSSQSTFEEEWVVSNITDTRFAVKNLVSFTE----YEMSVRAVSPAGEGPWSEPFRGMTFEEAEEEPYILAVGAEGLWKQRLDSYGPGEFLYP-HIRNISDLDWYNDTLYWSNSMGKVQTWSMNKKEGTTENSYVPDIKNARMLAFDWLGQCLY-WAGKANTIYRKSLLGDHMDVVAHVVYVVKDLAVDSVNGYLYWAT--TYTVESARLNGEEYLILQEHLQFSGKQVVGLALDLTSGFLYWLVQDGLCLNLYRISICKESCGNIMVTEISAWSVSEVSQNALQYYSGRLFWI-NRLKFITTQELNQSISIPF--SEPAEFAAFTLVHTSLKPLPGNFSFTPKVIPSSVPESSFKIKGNSSSFHIIWNASTDVQWGTVFYCVGSNALQMRTLESERCLHPHDLTVPSYKVDWLEPFTLFDFSVTPYTYWGKAPTTSVYLRAPEGVPSAPANPRIYVLHSNTHEGEEKVLVELRWDKPERDNGVLTQFRVYYQLLYESGAADTLMEWNVSDVKPTALLFSIRDEHPRLTVRFQVQAFTSVGPGPMSDVAQRNSSDIFPVPTLITFSS---NKLFLTDIDSNHTIWEVLTNRNIKDICYTADDD----KVYYILEDSLFLLNVQSTSESQLFEDVFLRNVTAITVDWIARHLFVAMKTSWNETQVFFIDLELKTKSLKALNIQLGKRNSTISSLLSYPFLSRLYWIEELDYGSRMFYYDILNNTMYHI-------LGYESVEEKMRNYCNCNVAEAELGRPISIDV---TDIKKPQLLFIRGRDEIWASDVDACHCWRITKIPSFQGTKIGSLTVDKQFIYWTIEKKEYTEICLADKESTRHSLQRKANHELKILAYSSAMQSYPDKKCLTPLLDTEKPTILDTTNTSFTLSLPSVTTQQLCPSISQPTPTYLVFFREITSNH---------ENSTYHFSTLLQKTLEIQEP-----IAVINNLKPFSTYAIQVAVKNYYSNQNQLAVGREAISTTLYGVPEGVDSIKTVVLSDTTINISWSEPLEPNGPLESIRYQISVNLLSLFPEAPLRKSEFPNG--------TLSWSVSDLQSGTNNLFKV-LAFHPNENWFSESVPVIAKTFETPLSP--SNIIPRNTSFQLEWRAPLHINGTSFWFELSKWQTR---SDWFSPAS-TTCTVGPVYTCNLTGTLPSANYLVRATVVYVTGMKS-------TSSPTSFKTTAGVPSKPGTPKRAEDSKNSVQWEKAEDNGSNLTYYILESRKQSGNT----NKVKSLWVVVYNGSCDNICTWKAENL-EGTFQFRAAAANMLGLGEYSD-----------TSKDIVLAKDTVTSPDITAIVAVIGAVVLGLTIIILFGFVWHQRWKSRKPASTGQIVLVKEDKELA-----QLRGMAETVGLANACYAVSTLPSQAEIESLPAFPRDKLNLHKLLGSGAFGEV 1975          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|341941008|sp|P08923.3|LTK_MOUSE (RecName: Full=Leukocyte tyrosine kinase receptor; Flags: Precursor)

HSP 1 Score: 187.578 bits (475), Expect = 4.782e-47
Identity = 88/172 (51.16%), Postives = 116/172 (67.44%), Query Frame = 0

Query: 1529 PRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQ 1700
            P +L  LT+ DL Q+  D+A+GC YL +  +IHRDIAARNCL+S   A  RV KIGDFG+ARDIY+ +YYRK G++LLP+KWM PE+L +  +T+K+D WSFGVLLWEI +LG   PYP   N +V+ F+  G     P NCP  +  +M +CW   P+ RP F   L  +Q
Sbjct:  605 PGQLAPLTMQDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCSGA-SRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEALLEGLFTSKTDSWSFGVLLWEIFSLGYM-PYPGHTNQEVLDFIATGNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSILERIQ 774          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|308153655|sp|P06213.4|INSR_HUMAN (RecName: Full=Insulin receptor; Short=IR; AltName: CD_antigen=CD220; Contains: RecName: Full=Insulin receptor subunit alpha; Contains: RecName: Full=Insulin receptor subunit beta; Flags: Precursor)

HSP 1 Score: 182.57 bits (462), Expect = 6.359e-45
Identity = 84/157 (53.50%), Postives = 112/157 (71.34%), Query Frame = 0

Query: 1536 TLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTF 1692
            TL ++ Q+  ++A G AYL+  +++HRD+AARNC+V    A D  VKIGDFG+ RDIY+  YYRK G+ LLP++WMAPESL D  +TT SD+WSFGV+LWEI +L    PY  ++N  V+ FV +GG+   P NCPER+ +LM  CW F+P  RPTF
Sbjct: 1132 TLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMV----AHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAE-QPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTF 1283          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|2497545|sp|Q05688.1|IGF1R_BOVIN (RecName: Full=Insulin-like growth factor 1 receptor; AltName: Full=Insulin-like growth factor I receptor; Short=IGF-I receptor; AltName: CD_antigen=CD221; Contains: RecName: Full=Insulin-like growth factor 1 receptor alpha chain; Contains: RecName: Full=Insulin-like growth factor 1 receptor beta chain; Flags: Precursor)

HSP 1 Score: 176.407 bits (446), Expect = 1.477e-44
Identity = 81/166 (48.80%), Postives = 113/166 (68.07%), Query Frame = 0

Query: 1536 TLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQE 1701
            +L+ + Q+  ++A G AYL+  +++HRD+AARNC+V    A+D  VKIGDFG+ RDIY+  YYRK G+ LLP++WM+PESL D  +TT SDVWSFGV+LWEI  L    PY  ++N  V+ FV  GG    P NCP+ L  LM  CW ++P  RP+F + +  V++
Sbjct:  381 SLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV----AEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAE-QPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSVKD 541          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|1061106905|ref|XP_017879766.1| (PREDICTED: proto-oncogene tyrosine-protein kinase ROS isoform X2 [Ceratina calcarata])

HSP 1 Score: 309.301 bits (791), Expect = 5.643e-81
Identity = 379/1637 (23.15%), Postives = 681/1637 (41.60%), Query Frame = 0

Query:    1 LAEKLGRIVDLQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNAN-VLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQ---AEETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAVL---LSTDTSLLSAQGQILFKANA-----------EISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEEDSKLVWRALT-----------GEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQMEI----NSLDTIIVHPDTLEQVLVE------LPSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDVGAIQTLDFQGPKAVF--SQGGSIFALNLINHVRERVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFSVD-----SGVLS--NVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQCSCFQMDPRSPFYFTLRPNIPEQKASLTLLTHDGSLFATD-NGCECQLM------RKIPAWSQLSSDGSNLYWK--SHEFVQYLNLQE---GQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQFRAPCTN----SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTL-----IKDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEK----EFSVELKDLEPGEIYKIWVEARTGSSKVAQSAEIEAQTFSRVSLPE---ITTRTPRSVTFIWRSPPIKAIQAF--QFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW---NSNNDLVESFELQA-RIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            +A  L R   +++D  NG +FW T   ++ +   D S+  +       I+  A LG+  +D  + RLLV    Q+ ++ + L   D  +++++    +Q  F+++    L   N  +YWTN   VL +     ++ +F +++    D     F    +        PV     +     LG    A+V W+            WQ W+Y++ ++ +S  E + Q   A  ++ V  +   + ++    A +  G+  WS     ++L +G    +L W     + +SD+ G N     L +KA      S   ++      D   +      L++ N             +  +  +  S+ +Y   PK   I R     S +E + I A  VK L +DSL A L W   G ++  + L G   R     ++++   +  L +D     +++  R   S +++++    +  IP+      Q V+ L+H    G L Y+ + L W+QD    V  DL GQ+ + I    L G     + D  +   P  +    + + P  V+ +S+++    K  WR              G V Y +    +    +    T+E  +    +  + P + + VT+ A + W  +    K L +P  + S P + RAF           ++   I RW+ P+  NG ITGY ++     N+++  I     +   L+E      LP+   +  +R     G  P + ++  +      +PQ+L+        +   DLD++         AI+         ++  ++   +   +L      ++L      L + VDW++  +++      + S R   +D     +G+L    +  T   I ++++ P T +LY+  LT     +  ++  L G  KS++P        C    P      T+  +   QK  +  ++ +G L   D +GC C L+      + +P  S L+ D  N+YW   + E + ++N ++   G+I HF   S      I+      Q  PI  CL+P  V   V  ++   + + VSLPQ   P  N    SLP   +TIY                 +   + P++C       +  + ++FQT      IKDL+PFT+Y + L+L       +++  E  +  + +T  G P  PENVT  AL P    V W+PPK+ N   + Y+VH+ L  +I  +R       K T++     F   L    P + Y ++V A         S  +  Q       P    +T  T  S+   W  P I     +  +++ V ++         W +    I    +    IK L P T Y  +  L  R       ++WP D  R   +T  D P  PG P V  K+  S   L W    ++   +  + ++  +I++ N  + D    ++W + Y  T   W I+G  D  Y FRV+A+N +G+  +S  +P +++          Q + G ++GL   ++ I+ +     L ++ +R  DKK+ L      ++ELAT+ E+P      ++SN  Y   + ++ +   +PK++R QITL  F+G GAFG+V
Sbjct:  450 VAGFLTRPTHIEVDPYNGYLFWVTRGGLYRLDLADISNGVKHEVQPYLILEDAHLGAFTVDHTNFRLLVPHHIQNTVISVSL---DGREVIDMRANTQQPKFKNVIS--LAMANGLFYWTNGEEVLIEGYHSGQNRYFHNAYP---DRSNGSFVSVNVLMDASQPVPVPVNPPTGVQAVLGVER-AKVSWQAPHLLGGQGKGAWQNWSYELEIKDESTGETIHQKDIAGSSHTVHNLREKSEYSIKAAAYTSAGRGPWSTEFRGRTLRDGSHASIL-WSANEGLLRSDVTGENID--TLIYKASLKEVESDYHIVDVSWYKDVLYIVGNNSALYRYNITNHQKFEMNIHSVGSVAVDWISKKLYWANPKQQIITRANLNGSHQEPISILAI-VKELMIDSLEAYLYW-STGHAVEVARLNGQDRRYYHSDEIFNGKQVMGLTLDTENRYIYWIVRSYESGSIVYRAPTSE-KIPMNQKIIPQKVSALQHPNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLHMVAVMDPALHQYPNNLTSDTVVVLPNAVNYNSIRV----KGTWRNFNISWDPVDNINYGTVFYEVKFADYINTNSNPEITTETSMPYNNSEQILPYSVLEVTVKAFTYWETAHHTRKILRSPQSVPSQPTNPRAFIEFHKEPLSENMDIFAIFRWDQPEFTNGLITGYTVQCWFKHNNVEMQICDQSLIPSTLLEHTVQDLLPNTTYYFQVRAHTEIGAGPYTDVINVSTIYENPVPQLLV---ATMDAVKISDLDQKVNYTITRHIAIEVAHLAAENRIYWINEMQELVTSDLNGANATKILKLNNSALSITVDWVARHLYWSESIYRENSGRIMKLDLTMWQAGILKYETIVTTSRRIVNLDILPSTGSLYWIELTKKDAGV-IMQSDLDG--KSIQPFFNPINDCCCPYRPSVIPVMTID-STNYQKPVMYWISMEGHLNIADIDGCMCSLILNTGFNKGLPPTS-LTVDKMNIYWSNMAEEQIYFINKKDPDDGEIKHFYLPSARS---IKALGKSLQTYPIANCLIPHQVSYNVEEIKKTANSITVSLPQ-PVPQFNCEAYSLPTTLYTIY---------------VSQCLENDPNMC-------EDSDRTKFQTYKKEYEIKDLKPFTKYRLKLALSNYYADLESMSLEFGSGVVLRTEAGAPTAPENVTVNALTPTLAIVYWMPPKILNAASVRYEVHWRLVPLINGARQKGEQFIKGTDRTADGRFFTMLDPWLPNQEYLVFVRAYPDHVNDVYSESL-GQVVKMYPEPNNLTLTGVTVNSMNVSW-IPTINLTAGYTLEYKDVAVE--------DWQVANDFIVDKEKVTYFIKKLQPRTLYKFR--LLLRYPNYKKDFVWPPDG-RFTFQTLGDVPSAPGMPTVT-KLRNSVYQLNWEPAQAHGSQITLYRVEGVKINEINEQI-DITENASWKLYYNGTDNYWIITGDMDDKYRFRVQARNAYGFGAWSRSSPVIDLTEATGGILAAQQHLGLVLGLIVPVITIVLICFCYFLCLYRQRKEDKKTVLP-PLMSDVELATLREIP--RGNFVQSNALYASTLHNDPDDSTLPKIRREQITLAKFLGSGAFGEV 2015          

HSP 2 Score: 207.994 bits (528), Expect = 6.784e-50
Identity = 98/179 (54.75%), Postives = 127/179 (70.95%), Query Frame = 0

Query: 1524 VQCRDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
            +Q  DP     L L DL  +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D  +T++SDVW+FGVL+WEI +LG+  PYP   N++V+  V  GG    P NCP  L  LMLRCW+   D RP+F+ CL  +  L
Sbjct: 2098 LQPTDPH---ALRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLIWEITSLGQ-QPYPARTNIEVLHHVRAGGRLPKPLNCPPGLHQLMLRCWS-AADARPSFKVCLESIVSL 2271          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|805790893|ref|XP_012141860.1| (PREDICTED: proto-oncogene tyrosine-protein kinase ROS isoform X3 [Megachile rotundata])

HSP 1 Score: 308.145 bits (788), Expect = 1.534e-80
Identity = 378/1648 (22.94%), Postives = 683/1648 (41.44%), Query Frame = 0

Query:    1 LAEKLGRIVDLQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNAN-VLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQ---AEETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAVLLST---DTSLLSAQGQILFKANA-----------EISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEEDSKLVWRALT-----------GEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQM---------EINSLDTIIVHPDTLEQVLVEL-PSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRE------------RVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFSVD-----SGVLS--NVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRP--NIPEQKASLTLLTHDGSLFATD-NGCECQ------LMRKIPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVI----------IRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLP----QFRAPCTNSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEK----EFSVELKDLEPGEIYKIWVEARTGS-SKVAQSAEIEA-QTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQ-AFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW---NSNNDLVESFELQA-RIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            +A  L R   +++D  NG +FW     ++ +   D S+  +       I+  A LG+  +D  + RLLV    Q+ ++ + L   D  ++L+L    +Q  F+++    L   N  +YWTN   VL +     ++ +F +++    D     F    +        PV     +     LG    A+V W+            WQ W+Y++ ++ +S  E + Q   A  ++ V  +   + ++    A +  G+  WS     Q+L +G    +L W     + +SD+ G N     L +KA      +   ++  T   D   +     +L++ N             +  +  +  S+ +Y   PK   I R     S +E + I A  VK L +DSL A L W   G ++  + L G   R     ++++   +  L +D     +++  R   S +++++    +  IP+      + V+ L+H    G L Y+ + L W+QD    V  DL GQ+ + I    L G     + D  +   P+ +  + + + P  V+  S+++E     +WR              G V Y +    +    +    T+E  +    +  + P + + VT+ A + W  +    K L +P  + + P + RAF           V+   I RW+ P+  NG ITGY +         EI   D  ++    LE  + +L P+   +  +R     G  P + ++  +      +PQ+L+        +   DLD+       +V    T       A  +    I+    IN +RE            ++LT +   L + VDW++  +++   +  D + R   +D      G+L   N+  +   I ++++ P T +LY+  LT  K     ++  L G  K  +P   H   CSC    P  P   ++    +   QK  +  ++ +G L   D +GC C         + +P  S L+ D  N+YW         N+ E QI   N    ++G I          I+      Q  P+  CL+P  V   V  ++   + + V LP    Q+     N LP   +TIY                 +   + P++C           E++++  IK+L+PFT Y + L+L       +++  E  +  + +T  G P PPENVT  AL P    V W+PP++ N   + Y++H+ L + I  +R       K  E+     F   L+   P + Y ++V A     + V   +E+ + + +   +   ++     S+   W       I+   +++ V ++         W +   S    H+    IK L P T Y  +  L  R    T  ++WP D  R   +T  D P  PG P V  K+  S   L W    ++   +  + ++  +I++ N  + D+   ++W + Y  T   W I+G  D  Y FRV+A+N +G+  +S  +P +++          Q + G ++GLS  ++ I+ +     L    R+  + K A+      ++ELAT+ E+P      ++SN  Y   + ++ +   +PK++R QITL  F+G GAFG+V
Sbjct:  409 VAGFLTRPTHIEVDPYNGYLFWVNRGGLYRLDLADISNGVKHEVQPYLILEDAHLGAFTVDHTNFRLLVPHHIQNTVISVSL---DGREVLDLRANTQQPKFKNVVS--LAMANGLFYWTNGEEVLIEGYHSGQNRYFHNAYP---DRSNGSFVSVNVLMDASQPVPVPVNPPTGVQAVLGVER-AKVSWQAPHLLGGQGKGAWQNWSYELEIKDESTGETIHQKDIAGSSHTVHNLREKSEYSIKAAAYTSAGRGPWSTEFRGQTLRDGSHASIL-WSANEGLLRSDVTGENID--TLIYKASLKETETDYHIVDVTWYKDVLYIVGNNSVLYRYNITSHQKMKMNIHSVGSVAVDWLSKKLYWANPKQQIITRADLNGSHQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVARLNGQDRRYYHSDEIFNGKQVMGLTLDTENRYVYWIVRSYESGSIVYRAPTSE-RIPMSHKIVPEKVSALQHPNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLHMVAVMDPALHQYPKNLTSETVVVLPNAVNYSSIRVEG----IWRNFNISWDPVENINYGTVFYEVKFADYINTNSNPEITTETSMPYNNSEQILPYSVLEVTVKAFTYWETAHHTRKILRSPQSVPTQPTNPRAFIEFHKEPLSENVDIFAIFRWDQPEFTNGLITGYTVQCWFIENHSEIQICDQSLIPVSLLEHTVQDLLPNTTYYFQVRAHTAIGAGPYTDVINISTIYENPVPQLLV---ATSDAVRVSDLDQ-------EVNYTITRHIAIEVAYLAAESKIY---WINEMRELVTSELNGANATKMLTLSNSALSITVDWVARNLYWSESNYRDNNGRIMKLDLTTWQVGILKYENIVASGRRIVNLDVLPSTGSLYWIELTK-KDTGEIIQSDLNG--KGRRPFFNHQDDCSC----PYQPTVISVMTIDSTNFQKPVMYWVSLEGHLNIADIDGCVCSSIVSASFNKGLPPTS-LTVDKMNIYWS--------NMAEDQIYFVNKKYPDDGEIKHFYLPTVRSIKALGKSLQSYPVTNCLIPHQVSYNVEEVKKEANSITVRLPRPVPQYGCEEYN-LPTTLYTIY---------------VSQCLENDPNMCEDTNRTKLQTYETKYE--IKNLKPFTEYRLKLALSNYYADLESMSLEFGSGVVLRTGAGAPTPPENVTVEALTPTLAIVYWMPPRILNAATVRYEIHWRLFRPINGARQKGEQLIKGNERTADGRFYSMLEPWLPDQEYHVFVRAYPAQFNNVFNDSEVRSVKMYPEPNNLTLSGVNVNSLNVTWEPTVNLTIRYTLEYKDVAME--------DWQVANDSKMDKHKVTYFIKKLQPRTLYKFR--LLLRYPNYTKDFVWPADG-RFTFQTLGDVPSAPGMPTVT-KLRSSVYQLNWEPAQAHGSQITLYRVEGMKINEINEQI-DSSENASWKLYYNGTDNYWIITGDMDDKYRFRVQARNAYGFGAWSRYSPIIDLTETTGGILAAQQHLGLVLGLSVPVITIMLICFCYFLCPLYRQRKEDKKAVLPPLVSDVELATLREIP--RGNFVQSNALYASTLQTDSDDSTLPKIRREQITLAKFLGSGAFGEV 1975          

HSP 2 Score: 209.534 bits (532), Expect = 2.437e-50
Identity = 99/179 (55.31%), Postives = 127/179 (70.95%), Query Frame = 0

Query: 1524 VQCRDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
            +Q  DP     L L DL  +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D  +T++SDVW+FGVL+WEI +LG+  PYP   NL+V+  V  GG    P NCP  L  LMLRCW+   D RP+F+ CL  +  L
Sbjct: 2058 LQPSDPH---ALRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLHHVRAGGRLPKPLNCPPVLHQLMLRCWS-AADARPSFKVCLENIVSL 2231          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|805790887|ref|XP_012141858.1| (PREDICTED: proto-oncogene tyrosine-protein kinase ROS isoform X1 [Megachile rotundata])

HSP 1 Score: 307.76 bits (787), Expect = 2.036e-80
Identity = 377/1649 (22.86%), Postives = 685/1649 (41.54%), Query Frame = 0

Query:    1 LAEKLGRIVDLQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNAN-VLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQ---AEETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAVLLST---DTSLLSAQGQILFKANA-----------EISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEEDSKLVWRALT-----------GEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQM---------EINSLDTIIVHPDTLEQVLVEL-PSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRE------------RVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFSVD-----SGVLS--NVTHTQDDIQHMELDPLTNTLYYTTLTSGKF-QLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRP--NIPEQKASLTLLTHDGSLFATD-NGCECQ------LMRKIPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVI----------IRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLP----QFRAPCTNSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEK----EFSVELKDLEPGEIYKIWVEARTGS-SKVAQSAEIEA-QTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQ-AFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW---NSNNDLVESFELQA-RIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            +A  L R   +++D  NG +FW     ++ +   D S+  +       I+  A LG+  +D  + RLLV    Q+ ++ + L   D  ++L+L    +Q  F+++    L   N  +YWTN   VL +     ++ +F +++    D     F    +        PV     +     LG    A+V W+            WQ W+Y++ ++ +S  E + Q   A  ++ V  +   + ++    A +  G+  WS     Q+L +G    +L W     + +SD+ G N     L +KA      +   ++  T   D   +     +L++ N             +  +  +  S+ +Y   PK   I R     S +E + I A  VK L +DSL A L W   G ++  + L G   R     ++++   +  L +D     +++  R   S +++++    +  IP+      + V+ L+H    G L Y+ + L W+QD    V  DL GQ+ + I    L G     + D  +   P+ +  + + + P  V+  S+++E     +WR              G V Y +    +    +    T+E  +    +  + P + + VT+ A + W  +    K L +P  + + P + RAF           V+   I RW+ P+  NG ITGY +         EI   D  ++    LE  + +L P+   +  +R     G  P + ++  +      +PQ+L+        +   DLD+       +V    T       A  +    I+    IN +RE            ++LT +   L + VDW++  +++   +  D + R   +D      G+L   N+  +   I ++++ P T +LY+  LT     ++ + +L+  GR    +P   H   CSC    P  P   ++    +   QK  +  ++ +G L   D +GC C         + +P  S L+ D  N+YW         N+ E QI   N    ++G I          I+      Q  P+  CL+P  V   V  ++   + + V LP    Q+     N LP   +TIY                 +   + P++C           E++++  IK+L+PFT Y + L+L       +++  E  +  + +T  G P PPENVT  AL P    V W+PP++ N   + Y++H+ L + I  +R       K  E+     F   L+   P + Y ++V A     + V   +E+ + + +   +   ++     S+   W       I+   +++ V ++         W +   S    H+    IK L P T Y  +  L  R    T  ++WP D  R   +T  D P  PG P V  K+  S   L W    ++   +  + ++  +I++ N  + D+   ++W + Y  T   W I+G  D  Y FRV+A+N +G+  +S  +P +++          Q + G ++GLS  ++ I+ +     L    R+  + K A+      ++ELAT+ E+P      ++SN  Y   + ++ +   +PK++R QITL  F+G GAFG+V
Sbjct:  452 VAGFLTRPTHIEVDPYNGYLFWVNRGGLYRLDLADISNGVKHEVQPYLILEDAHLGAFTVDHTNFRLLVPHHIQNTVISVSL---DGREVLDLRANTQQPKFKNVVS--LAMANGLFYWTNGEEVLIEGYHSGQNRYFHNAYP---DRSNGSFVSVNVLMDASQPVPVPVNPPTGVQAVLGVER-AKVSWQAPHLLGGQGKGAWQNWSYELEIKDESTGETIHQKDIAGSSHTVHNLREKSEYSIKAAAYTSAGRGPWSTEFRGQTLRDGSHASIL-WSANEGLLRSDVTGENID--TLIYKASLKETETDYHIVDVTWYKDVLYIVGNNSVLYRYNITSHQKMKMNIHSVGSVAVDWLSKKLYWANPKQQIITRADLNGSHQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVARLNGQDRRYYHSDEIFNGKQVMGLTLDTENRYVYWIVRSYESGSIVYRAPTSE-RIPMSHKIVPEKVSALQHPNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLHMVAVMDPALHQYPKNLTSETVVVLPNAVNYSSIRVEG----IWRNFNISWDPVENINYGTVFYEVKFADYINTNSNPEITTETSMPYNNSEQILPYSVLEVTVKAFTYWETAHHTRKILRSPQSVPTQPTNPRAFIEFHKEPLSENVDIFAIFRWDQPEFTNGLITGYTVQCWFIENHSEIQICDQSLIPVSLLEHTVQDLLPNTTYYFQVRAHTAIGAGPYTDVINISTIYENPVPQLLV---ATSDAVRVSDLDQ-------EVNYTITRHIAIEVAYLAAESKIY---WINEMRELVTSELNGANATKMLTLSNSALSITVDWVARNLYWSESNYRDNNGRIMKLDLTTWQVGILKYENIVASGRRIVNLDVLPSTGSLYWIELTKKDTGEIIQSDLNGKGR----RPFFNHQDDCSC----PYQPTVISVMTIDSTNFQKPVMYWVSLEGHLNIADIDGCVCSSIVSASFNKGLPPTS-LTVDKMNIYWS--------NMAEDQIYFVNKKYPDDGEIKHFYLPTVRSIKALGKSLQSYPVTNCLIPHQVSYNVEEVKKEANSITVRLPRPVPQYGCEEYN-LPTTLYTIY---------------VSQCLENDPNMCEDTNRTKLQTYETKYE--IKNLKPFTEYRLKLALSNYYADLESMSLEFGSGVVLRTGAGAPTPPENVTVEALTPTLAIVYWMPPRILNAATVRYEIHWRLFRPINGARQKGEQLIKGNERTADGRFYSMLEPWLPDQEYHVFVRAYPAQFNNVFNDSEVRSVKMYPEPNNLTLSGVNVNSLNVTWEPTVNLTIRYTLEYKDVAME--------DWQVANDSKMDKHKVTYFIKKLQPRTLYKFR--LLLRYPNYTKDFVWPADG-RFTFQTLGDVPSAPGMPTVT-KLRSSVYQLNWEPAQAHGSQITLYRVEGMKINEINEQI-DSSENASWKLYYNGTDNYWIITGDMDDKYRFRVQARNAYGFGAWSRYSPIIDLTETTGGILAAQQHLGLVLGLSVPVITIMLICFCYFLCPLYRQRKEDKKAVLPPLVSDVELATLREIP--RGNFVQSNALYASTLQTDSDDSTLPKIRREQITLAKFLGSGAFGEV 2018          

HSP 2 Score: 209.534 bits (532), Expect = 2.655e-50
Identity = 99/179 (55.31%), Postives = 127/179 (70.95%), Query Frame = 0

Query: 1524 VQCRDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
            +Q  DP     L L DL  +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D  +T++SDVW+FGVL+WEI +LG+  PYP   NL+V+  V  GG    P NCP  L  LMLRCW+   D RP+F+ CL  +  L
Sbjct: 2101 LQPSDPH---ALRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLHHVRAGGRLPKPLNCPPVLHQLMLRCWS-AADARPSFKVCLENIVSL 2274          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|805790890|ref|XP_012141859.1| (PREDICTED: proto-oncogene tyrosine-protein kinase ROS isoform X2 [Megachile rotundata])

HSP 1 Score: 307.375 bits (786), Expect = 2.755e-80
Identity = 377/1649 (22.86%), Postives = 686/1649 (41.60%), Query Frame = 0

Query:    1 LAEKLGRIVDLQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNAN-VLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQ---AEETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAVLLST---DTSLLSAQGQILFKANA-----------EISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEEDSKLVWRALT-----------GEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQM---------EINSLDTIIVHPDTLEQVLVEL-PSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRE------------RVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFSVD-----SGVLS--NVTHTQDDIQHMELDPLTNTLYYTTLTSGKF-QLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRP--NIPEQKASLTLLTHDGSLFATD-NGCECQLM------RKIPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVI----------IRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLP----QFRAPCTNSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEK----EFSVELKDLEPGEIYKIWVEARTGS-SKVAQSAEIEA-QTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQ-AFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW---NSNNDLVESFELQA-RIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            +A  L R   +++D  NG +FW     ++ +   D S+  +       I+  A LG+  +D  + RLLV    Q+ ++ + L   D  ++L+L    +Q  F+++    L   N  +YWTN   VL +     ++ +F +++    D     F    +        PV     +     LG    A+V W+            WQ W+Y++ ++ +S  E + Q   A  ++ V  +   + ++    A +  G+  WS     Q+L +G    +L W     + +SD+ G N     L +KA      +   ++  T   D   +     +L++ N             +  +  +  S+ +Y   PK   I R     S +E + I A  VK L +DSL A L W   G ++  + L G   R     ++++   +  L +D     +++  R   S +++++    +  IP+      + V+ L+H    G L Y+ + L W+QD    V  DL GQ+ + I    L G     + D  +   P+ +  + + + P  V+  S+++E     +WR              G V Y +    +    +    T+E  +    +  + P + + VT+ A + W  +    K L +P  + + P + RAF           V+   I RW+ P+  NG ITGY +         EI   D  ++    LE  + +L P+   +  +R     G  P + ++  +      +PQ+L+        +   DLD+       +V    T       A  +    I+    IN +RE            ++LT +   L + VDW++  +++   +  D + R   +D      G+L   N+  +   I ++++ P T +LY+  LT     ++ + +L+  GR    +P   H   CSC    P  P   ++    +   QK  +  ++ +G L   D +GC C  +      + +P  S L+ D  N+YW         N+ E QI   N    ++G I          I+      Q  P+  CL+P  V   V  ++   + + V LP    Q+     N LP   +TIY                 +   + P++C           E++++  IK+L+PFT Y + L+L       +++  E  +  + +T  G P PPENVT  AL P    V W+PP++ N   + Y++H+ L + I  +R       K  E+     F   L+   P + Y ++V A     + V   +E+ + + +   +   ++     S+   W       I+   +++ V ++         W +   S    H+    IK L P T Y  +  L  R    T  ++WP D  R   +T  D P  PG P V  K+  S   L W    ++   +  + ++  +I++ N  + D+   ++W + Y  T   W I+G  D  Y FRV+A+N +G+  +S  +P +++          Q + G ++GLS  ++ I+ +     L    R+  + K A+      ++ELAT+ E+P      ++SN  Y   + ++ +   +PK++R QITL  F+G GAFG+V
Sbjct:  452 VAGFLTRPTHIEVDPYNGYLFWVNRGGLYRLDLADISNGVKHEVQPYLILEDAHLGAFTVDHTNFRLLVPHHIQNTVISVSL---DGREVLDLRANTQQPKFKNVVS--LAMANGLFYWTNGEEVLIEGYHSGQNRYFHNAYP---DRSNGSFVSVNVLMDASQPVPVPVNPPTGVQAVLGVER-AKVSWQAPHLLGGQGKGAWQNWSYELEIKDESTGETIHQKDIAGSSHTVHNLREKSEYSIKAAAYTSAGRGPWSTEFRGQTLRDGSHASIL-WSANEGLLRSDVTGENID--TLIYKASLKETETDYHIVDVTWYKDVLYIVGNNSVLYRYNITSHQKMKMNIHSVGSVAVDWLSKKLYWANPKQQIITRADLNGSHQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVARLNGQDRRYYHSDEIFNGKQVMGLTLDTENRYVYWIVRSYESGSIVYRAPTSE-RIPMSHKIVPEKVSALQHPNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLHMVAVMDPALHQYPKNLTSETVVVLPNAVNYSSIRVEG----IWRNFNISWDPVENINYGTVFYEVKFADYINTNSNPEITTETSMPYNNSEQILPYSVLEVTVKAFTYWETAHHTRKILRSPQSVPTQPTNPRAFIEFHKEPLSENVDIFAIFRWDQPEFTNGLITGYTVQCWFIENHSEIQICDQSLIPVSLLEHTVQDLLPNTTYYFQVRAHTAIGAGPYTDVINISTIYENPVPQLLV---ATSDAVRVSDLDQ-------EVNYTITRHIAIEVAYLAAESKIY---WINEMRELVTSELNGANATKMLTLSNSALSITVDWVARNLYWSESNYRDNNGRIMKLDLTTWQVGILKYENIVASGRRIVNLDVLPSTGSLYWIELTKKDTGEIIQSDLNGKGR----RPFFNHQDDCSC----PYQPTVISVMTIDSTNFQKPVMYWVSLEGHLNIADIDGCVCSSIVSASFNKGLPPTS-LTVDKMNIYWS--------NMAEDQIYFVNKKYPDDGEIKHFYLPTVRSIKALGKSLQSYPVTNCLIPHQVSYNVEEVKKEANSITVRLPRPVPQYGCEEYN-LPTTLYTIY---------------VSQCLENDPNMCEDTNRTKLQTYETKYE--IKNLKPFTEYRLKLALSNYYADLESMSLEFGSGVVLRTGAGAPTPPENVTVEALTPTLAIVYWMPPRILNAATVRYEIHWRLFRPINGARQKGEQLIKGNERTADGRFYSMLEPWLPDQEYHVFVRAYPAQFNNVFNDSEVRSVKMYPEPNNLTLSGVNVNSLNVTWEPTVNLTIRYTLEYKDVAME--------DWQVANDSKMDKHKVTYFIKKLQPRTLYKFR--LLLRYPNYTKDFVWPADG-RFTFQTLGDVPSAPGMPTVT-KLRSSVYQLNWEPAQAHGSQITLYRVEGMKINEINEQI-DSSENASWKLYYNGTDNYWIITGDMDDKYRFRVQARNAYGFGAWSRYSPIIDLTETTGGILAAQQHLGLVLGLSVPVITIMLICFCYFLCPLYRQRKEDKKAVLPPLVSDVELATLREIP--RGNFVQSNALYASTLQTDSDDSTLPKIRREQITLAKFLGSGAFGEV 2018          

HSP 2 Score: 209.149 bits (531), Expect = 2.966e-50
Identity = 99/179 (55.31%), Postives = 127/179 (70.95%), Query Frame = 0

Query: 1524 VQCRDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
            +Q  DP     L L DL  +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D  +T++SDVW+FGVL+WEI +LG+  PYP   NL+V+  V  GG    P NCP  L  LMLRCW+   D RP+F+ CL  +  L
Sbjct: 2101 LQPSDPH---ALRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLHHVRAGGRLPKPLNCPPVLHQLMLRCWS-AADARPSFKVCLENIVSL 2274          

BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|805790899|ref|XP_012141862.1| (PREDICTED: proto-oncogene tyrosine-protein kinase ROS isoform X5 [Megachile rotundata])

HSP 1 Score: 306.99 bits (785), Expect = 2.902e-80
Identity = 378/1648 (22.94%), Postives = 683/1648 (41.44%), Query Frame = 0

Query:    1 LAEKLGRIVDLQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNAN-VLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQ---AEETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAVLLST---DTSLLSAQGQILFKANA-----------EISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEEDSKLVWRALT-----------GEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQM---------EINSLDTIIVHPDTLEQVLVEL-PSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRE------------RVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFSVD-----SGVLS--NVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRP--NIPEQKASLTLLTHDGSLFATD-NGCECQ------LMRKIPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVI----------IRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLP----QFRAPCTNSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEK----EFSVELKDLEPGEIYKIWVEARTGS-SKVAQSAEIEA-QTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQ-AFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW---NSNNDLVESFELQA-RIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
            +A  L R   +++D  NG +FW     ++ +   D S+  +       I+  A LG+  +D  + RLLV    Q+ ++ + L   D  ++L+L    +Q  F+++    L   N  +YWTN   VL +     ++ +F +++    D     F    +        PV     +     LG    A+V W+            WQ W+Y++ ++ +S  E + Q   A  ++ V  +   + ++    A +  G+  WS     Q+L +G    +L W     + +SD+ G N     L +KA      +   ++  T   D   +     +L++ N             +  +  +  S+ +Y   PK   I R     S +E + I A  VK L +DSL A L W   G ++  + L G   R     ++++   +  L +D     +++  R   S +++++    +  IP+      + V+ L+H    G L Y+ + L W+QD    V  DL GQ+ + I    L G     + D  +   P+ +  + + + P  V+  S+++E     +WR              G V Y +    +    +    T+E  +    +  + P + + VT+ A + W  +    K L +P  + + P + RAF           V+   I RW+ P+  NG ITGY +         EI   D  ++    LE  + +L P+   +  +R     G  P + ++  +      +PQ+L+        +   DLD+       +V    T       A  +    I+    IN +RE            ++LT +   L + VDW++  +++   +  D + R   +D      G+L   N+  +   I ++++ P T +LY+  LT  K     ++  L G  K  +P   H   CSC    P  P   ++    +   QK  +  ++ +G L   D +GC C         + +P  S L+ D  N+YW         N+ E QI   N    ++G I          I+      Q  P+  CL+P  V   V  ++   + + V LP    Q+     N LP   +TIY                 +   + P++C           E++++  IK+L+PFT Y + L+L       +++  E  +  + +T  G P PPENVT  AL P    V W+PP++ N   + Y++H+ L + I  +R       K  E+     F   L+   P + Y ++V A     + V   +E+ + + +   +   ++     S+   W       I+   +++ V ++         W +   S    H+    IK L P T Y  +  L  R    T  ++WP D  R   +T  D P  PG P V  K+  S   L W    ++   +  + ++  +I++ N  + D+   ++W + Y  T   W I+G  D  Y FRV+A+N +G+  +S  +P +++          Q + G ++GLS  ++ I+ +     L    R+  + K A+      ++ELAT+ E+P      ++SN  Y   + ++ +   +PK++R QITL  F+G GAFG+V
Sbjct:  162 VAGFLTRPTHIEVDPYNGYLFWVNRGGLYRLDLADISNGVKHEVQPYLILEDAHLGAFTVDHTNFRLLVPHHIQNTVISVSL---DGREVLDLRANTQQPKFKNVVS--LAMANGLFYWTNGEEVLIEGYHSGQNRYFHNAYP---DRSNGSFVSVNVLMDASQPVPVPVNPPTGVQAVLGVER-AKVSWQAPHLLGGQGKGAWQNWSYELEIKDESTGETIHQKDIAGSSHTVHNLREKSEYSIKAAAYTSAGRGPWSTEFRGQTLRDGSHASIL-WSANEGLLRSDVTGENID--TLIYKASLKETETDYHIVDVTWYKDVLYIVGNNSVLYRYNITSHQKMKMNIHSVGSVAVDWLSKKLYWANPKQQIITRADLNGSHQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVARLNGQDRRYYHSDEIFNGKQVMGLTLDTENRYVYWIVRSYESGSIVYRAPTSE-RIPMSHKIVPEKVSALQHPNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLHMVAVMDPALHQYPKNLTSETVVVLPNAVNYSSIRVEG----IWRNFNISWDPVENINYGTVFYEVKFADYINTNSNPEITTETSMPYNNSEQILPYSVLEVTVKAFTYWETAHHTRKILRSPQSVPTQPTNPRAFIEFHKEPLSENVDIFAIFRWDQPEFTNGLITGYTVQCWFIENHSEIQICDQSLIPVSLLEHTVQDLLPNTTYYFQVRAHTAIGAGPYTDVINISTIYENPVPQLLV---ATSDAVRVSDLDQ-------EVNYTITRHIAIEVAYLAAESKIY---WINEMRELVTSELNGANATKMLTLSNSALSITVDWVARNLYWSESNYRDNNGRIMKLDLTTWQVGILKYENIVASGRRIVNLDVLPSTGSLYWIELTK-KDTGEIIQSDLNG--KGRRPFFNHQDDCSC----PYQPTVISVMTIDSTNFQKPVMYWVSLEGHLNIADIDGCVCSSIVSASFNKGLPPTS-LTVDKMNIYWS--------NMAEDQIYFVNKKYPDDGEIKHFYLPTVRSIKALGKSLQSYPVTNCLIPHQVSYNVEEVKKEANSITVRLPRPVPQYGCEEYN-LPTTLYTIY---------------VSQCLENDPNMCEDTNRTKLQTYETKYE--IKNLKPFTEYRLKLALSNYYADLESMSLEFGSGVVLRTGAGAPTPPENVTVEALTPTLAIVYWMPPRILNAATVRYEIHWRLFRPINGARQKGEQLIKGNERTADGRFYSMLEPWLPDQEYHVFVRAYPAQFNNVFNDSEVRSVKMYPEPNNLTLSGVNVNSLNVTWEPTVNLTIRYTLEYKDVAME--------DWQVANDSKMDKHKVTYFIKKLQPRTLYKFR--LLLRYPNYTKDFVWPADG-RFTFQTLGDVPSAPGMPTVT-KLRSSVYQLNWEPAQAHGSQITLYRVEGMKINEINEQI-DSSENASWKLYYNGTDNYWIITGDMDDKYRFRVQARNAYGFGAWSRYSPIIDLTETTGGILAAQQHLGLVLGLSVPVITIMLICFCYFLCPLYRQRKEDKKAVLPPLVSDVELATLREIP--RGNFVQSNALYASTLQTDSDDSTLPKIRREQITLAKFLGSGAFGEV 1728          

HSP 2 Score: 210.305 bits (534), Expect = 1.389e-50
Identity = 99/179 (55.31%), Postives = 127/179 (70.95%), Query Frame = 0

Query: 1524 VQCRDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
            +Q  DP     L L DL  +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D  +T++SDVW+FGVL+WEI +LG+  PYP   NL+V+  V  GG    P NCP  L  LMLRCW+   D RP+F+ CL  +  L
Sbjct: 1811 LQPSDPH---ALRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLHHVRAGGRLPKPLNCPPVLHQLMLRCWS-AADARPSFKVCLENIVSL 1984