proto-oncogene tyrosine-protein kinase ros, maker-scaffold233_size243130-snap-gene-1.22 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000005077 (supercontig:LSalAtl2s:LSalAtl2s268:114393:146217:-1 gene:EMLSAG00000005077 transcript:EMLSAT00000005077 description:"maker-LSalAtl2s268-snap-gene-1.30") HSP 1 Score: 202.216 bits (513), Expect = 1.177e-53 Identity = 95/177 (53.67%), Postives = 130/177 (73.45%), Query Frame = 0
Query: 1539 DLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDR--VVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHP-KVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELAEI 1712
+L + C D+A+GC YL+ M+++HRDIAARNCLVS L D +VKIGDFG AR+IY+D YYRK G L+PI+WMAPESL D YT ++DVWS+G++LWEI++ G+ PYP M++LDV +V N VP CP L LM +CW++ P RP+F++C+ E++ELL+Y+DEL I
Sbjct: 570 NLVRFCLDIARGCLYLTQMRHVHRDIAARNCLVS-LPTSDHTHLVKIGDFGRAREIYRDDYYRKGG--LMPIRWMAPESLEDGVYTHQTDVWSYGIVLWEIISFGK-QPYPGMSHLDVYHYVCNLRKTLDVPLKCPHILYQLMTQCWSYEPINRPSFKECVDEIEELLLYKDELNGI 742 HSP 2 Score: 145.591 bits (366), Expect = 1.932e-35 Identity = 127/460 (27.61%), Postives = 199/460 (43.26%), Query Frame = 0
Query: 1096 AQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEKEFSVELKDLEPGEIYKIWVEA--RTGSSK-VAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQ--PGHQYQGQIKS-LNPGTQYGLQ-----GVLTFRIGQRT------HTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWNSNNDLVESFELQARIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMES-----NPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV-----QCRD 1528
+T + P P++V + P I V W+ P NG + Y VH + SG + ELK L P +Y IW+ A RT SK + S I +TF L ++ + PRS+ W+SP + F L L +N N S +W S+ + P Y QI + L P T Y ++ G I + + ++WP D + V T PD PL PG PY+ E + + V L W+ + ++ +EL + + + W + Y D WP S L+D+ Y F+VRAKNE GWS FS+ + +NI LIL K +S L+G + I +V + +++ + + +++I V+LN +S NP Y + + + I +Q++ +G GAFG V QC +
Sbjct: 65 TRTEEDIPNNPQHVKGLSKTPSFIFVTWMAPLTFNGS-VAYMVHAKY----------SGITSVYNTTDLEYELKGLNPNSLYVIWISAYLRTNISKGYSSSKRISIKTFKSPPLVQVLQKGPRSLKLHWKSPNSETPVVFHQFL--LYTNQNKSDIRWFPSNSAQRTFPSQNYTTQISTGLYPSTMYIIKVRLFYGEYHINISSQDEQISSLNEFVWPLDDYMLAVNTLPDTPLEPGIPYIFE--NGTYVILIWSGGDMNIDLYELYGK------EINGDGNFYGWBLXYXDVKNFWPPSMLNDSVYKFKVRAKNEHGWSNFSQSSQFININLILQRKK--KSEISILVGSICFSISIFCSIVFYLSFTIIKKTSKNQKS----------ISSISNDLVILNEFRDSFVSANNPLYNL---IGENLSPIKHFSLSQLSFKTKLGSGAFGNVYEGTLQCSE 488
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000005080 (supercontig:LSalAtl2s:LSalAtl2s268:283763:286301:1 gene:EMLSAG00000005080 transcript:EMLSAT00000005080 description:"maker-LSalAtl2s268-augustus-gene-3.12") HSP 1 Score: 157.147 bits (396), Expect = 5.778e-40 Identity = 78/177 (44.07%), Postives = 104/177 (58.76%), Query Frame = 0
Query: 1539 DLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELAEIPSF 1715
DL VAK YLS + IHRD+AARN L+ D ++ K+ DFG ARDI + Y + LPI+WMAPESL N Y+T+SDVWSFG+LLWEI+ LG PYP + DV+ F+ G + P +C L NLM CW PD RP F+ + + ++LL+ E ++ F
Sbjct: 398 DLTSYAYQVAKAMEYLSCKKIIHRDLAARNVLI---DYTLQICKVVDFGFARDIMNHSIYERKSDGRLPIRWMAPESLLYNIYSTRSDVWSFGILLWEIVTLGS-TPYPGKSASDVIKFIREGHRLEKPEHCGRELYNLMYYCWVKKPDDRPCFKTLVKDFEKLLLQETNYIDLRIF 570
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000010076 (supercontig:LSalAtl2s:LSalAtl2s663:706586:714919:-1 gene:EMLSAG00000010076 transcript:EMLSAT00000010076 description:"maker-LSalAtl2s663-augustus-gene-7.10") HSP 1 Score: 150.599 bits (379), Expect = 4.886e-39 Identity = 73/164 (44.51%), Postives = 105/164 (64.02%), Query Frame = 0
Query: 1540 LGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELL 1703
L + DVAKG AYL+D++Y+HRDIA RNCLV+S R+VK+ DFG+ R +Y++ YYR N + +LP++WM+PESLAD +T SDVWS+GVLL+E++ G P+ ++N V+ V G +P +L+ L+ CW +RPT E+ ELL
Sbjct: 107 LTSMALDVAKGLAYLADLKYVHRDIACRNCLVNS----SRIVKLADFGMTRPMYENDYYRFNRKGMLPVRWMSPESLADGLFTPMSDVWSYGVLLYEMITFGSF-PFQGLSNNQVLEHVKAGNTLSIPSGIKAQLETLLKSCWNIASTKRPT----AAEIAELL 261
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000012370 (supercontig:LSalAtl2s:LSalAtl2s905:198215:201197:-1 gene:EMLSAG00000012370 transcript:EMLSAT00000012370 description:"maker-LSalAtl2s905-augustus-gene-2.8") HSP 1 Score: 144.821 bits (364), Expect = 1.691e-37 Identity = 72/182 (39.56%), Postives = 105/182 (57.69%), Query Frame = 0
Query: 1523 QVQCRDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLV 1704
+Q R RLL L+ ++ ++KG +LS + +HRD+AARN L+ A V+KI DFG+ARD+ YYRK LPIKWMAPE+ N Y+T+SDVWS+G+LLWEI N G P +++ + + G P +CP+ +LM CW +HP++RP + + + LL
Sbjct: 76 HLQKRKNERLL-LSSEEMYSFSNQISKGMNFLSKRKCVHRDLAARNILL----ADKNVIKIADFGMARDVNGKEYYRKRSGGKLPIKWMAPEAFFQNFYSTQSDVWSYGILLWEIANYGEQPYREIFDHITLFKKLDEGYRLSKPSDCPQIFYDLMKYCWKYHPEERPNWENLITLTDSLLA 252
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000003046 (supercontig:LSalAtl2s:LSalAtl2s172:225319:228324:-1 gene:EMLSAG00000003046 transcript:EMLSAT00000003046 description:"maker-LSalAtl2s172-snap-gene-2.21") HSP 1 Score: 142.895 bits (359), Expect = 8.231e-35 Identity = 78/196 (39.80%), Postives = 115/196 (58.67%), Query Frame = 0
Query: 1534 KLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRD---CLHEVQELLVYEDELAEIPSFCQFNPTSHPNS 1726
+L L+ L ++ +YL +++HRDIAARN LVSS + VVK+ DFGL+R I ++YY K + LPIKWM+PES+ ++TT SDVW FGV +WEI+ LG P+ + N DV+ + G +P CP L ++ML+CW++ P RPTF++ L E + +D L + Q + S P+S
Sbjct: 214 RLDLSHLILYSHQLSTALSYLESKKFVHRDIAARNVLVSS----ENVVKLADFGLSRWIEHNSYY-KASRGKLPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLG-VKPFQGIKNSDVIGKLEKGERLSLPSGCPSHLYSVMLQCWSYEPSNRPTFQELKSVLFETLNEIKIQDSLGGYATPWQGDNNSIPSS 403
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000009561 (supercontig:LSalAtl2s:LSalAtl2s615:613087:620800:1 gene:EMLSAG00000009561 transcript:EMLSAT00000009561 description:"maker-LSalAtl2s615-snap-gene-5.55") HSP 1 Score: 131.724 bits (330), Expect = 5.614e-31 Identity = 69/178 (38.76%), Postives = 104/178 (58.43%), Query Frame = 0
Query: 1533 LKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELA 1710
+K++ + I + G YLSD +Y+HRD+A+RNCL+ + VKI DFGL++ + Y+R + +PI+WM E++ NKYT +SD+W+FG+LLWEI +L PY ++N +V+ F+ G P N P+ + +M CW +P RP FR LH +EL E EL
Sbjct: 736 IKVSHVEQVSISKQICNGMVYLSDRKYVHRDLASRNCLID----QSGTVKIADFGLSQRVSLQEYFRGDVSDNIPIRWMPLEAVLHNKYTIESDIWAFGILLWEIFSLA-LQPYYGLSNEEVIKFLKEGNTLGCPENTPKSIYKIMKSCWNPNPSVRPMFR-ILH--RELETIEKELT 905
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000000181 (supercontig:LSalAtl2s:LSalAtl2s1027:89631:95641:1 gene:EMLSAG00000000181 transcript:EMLSAT00000000181 description:"maker-LSalAtl2s1027-augustus-gene-0.8") HSP 1 Score: 129.028 bits (323), Expect = 4.498e-30 Identity = 78/213 (36.62%), Postives = 116/213 (54.46%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLR-CWAFHPDQRPTF---RDCLH-------EVQELLVYE-------DEL---AEIPSFCQFNPTSHPNS 1726
L DL + G YLS Q +HRD+A RN L+ AK+ V+KI DFGL+R++YK S +P+KW++ ESL +T +SD+WSFGV+LWE+ LGR PYP+M +++ F+ +G + P CP+ + ++R CW+ +P +RP++ RD +++EL E DEL E F NPT P+S
Sbjct: 911 LKTEDLLDWAMQITNGMEYLSQKQVVHRDLACRNILI----AKNNVIKICDFGLSRNMYKTYSSSNKKSSPVPVKWLSIESLKYGTFTRRSDIWSFGVVLWEMFTLGRL-PYPNMEYGNLLPFLESGKRMEQPMYCPDSIYYRIMRICWSENPSERPSWIAMRDTFEFMVSNKRDMEELATTEEIRHPNLDELLTNIETNGFIVNNPTYLPDS 1118
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000002397 (supercontig:LSalAtl2s:LSalAtl2s145:1463521:1466086:-1 gene:EMLSAG00000002397 transcript:EMLSAT00000002397 description:"maker-LSalAtl2s145-augustus-gene-15.23") HSP 1 Score: 118.627 bits (296), Expect = 1.020e-29 Identity = 59/169 (34.91%), Postives = 94/169 (55.62%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELL 1703
+T D+ +AKG YL ++++HRD+AARN L++ + Y P+KW++PESL DNKYT+KSDVWSFG+LLWE++ G C PYP + ++ + +G + P +C + +M CW+++PD RPTF++ + ++ LL
Sbjct: 20 ITPQDVIGFSLQIAKGMEYLFGLKFVHRDLAARNVLLT----------------------EGYQ-------FPVKWLSPESLFDNKYTSKSDVWSFGILLWELVXFGGC-PYPGIPPERLVKLLKSGYRMEKPDSCTGEIYEIMTDCWSYNPDARPTFKNLIMRIEILL 158
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000000685 (supercontig:LSalAtl2s:LSalAtl2s1108:63543:67697:1 gene:EMLSAG00000000685 transcript:EMLSAT00000000685 description:"maker-LSalAtl2s1108-augustus-gene-0.17") HSP 1 Score: 110.538 bits (275), Expect = 2.083e-24 Identity = 63/180 (35.00%), Postives = 96/180 (53.33%), Query Frame = 0
Query: 1524 VQC-RDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLAR--DIYKDAYYRK-NGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFV--PNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLH 1697
++C +P ++ L + + +G +YL + + IHRD+AARN LV S + VVKI DFGL+R + KD Y N LPI W APE + K+T+ SDVW+F LWE+ + G P+ + ++ + P+ + PP CP+ +M+ CW+ P +RPTF H
Sbjct: 223 LECLNEPSSRSSFHVSRLSEFSLQICQGMSYLEEKRLIHRDLAARNILVFSKE----VVKISDFGLSRALGVGKDYYQTNFNANLKLPIAWCAPECINFLKFTSASDVWAFSTALWEMFSYG-FQPWAGLTGKQILDAIDEPHSRRLERPPYCPKDYYRIMMECWSHDPIKRPTFARLYH 397
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Match: EMLSAG00000010861 (supercontig:LSalAtl2s:LSalAtl2s721:338828:344970:1 gene:EMLSAG00000010861 transcript:EMLSAT00000010861 description:"maker-LSalAtl2s721-augustus-gene-2.54") HSP 1 Score: 103.99 bits (258), Expect = 2.205e-22 Identity = 58/170 (34.12%), Postives = 88/170 (51.76%), Query Frame = 0
Query: 1534 KLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDI-YKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVP-NGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTF---RDCLHE 1698
++ + ++ +A G YL ++IHRD+A RN L+ A +KIGDFGL R + KD +Y ++ +P W APESL + ++ SD W F V LWE+ + G+ P+ +N ++ + G P CP + L+L CWA P RP F +D L E
Sbjct: 237 RIPITNIWDFAIQIANGMTYLESKRFIHRDLACRNVLL----ATSSRIKIGDFGLMRALTQKDDFYVMTERNKVPFPWCAPESLKNRLFSHASDTWMFAVTLWEMFSFGQ-EPWLGLNGTQILRKIDVEGERLGQPYACPNYIYRLLLECWAKVPTDRPNFESLKDLLTE 401
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|341940209|sp|P97793.2|ALK_MOUSE (RecName: Full=ALK tyrosine kinase receptor; AltName: Full=Anaplastic lymphoma kinase; AltName: CD_antigen=CD246; Flags: Precursor) HSP 1 Score: 181.8 bits (460), Expect = 1.682e-44 Identity = 82/172 (47.67%), Postives = 113/172 (65.70%), Query Frame = 0
Query: 1529 PRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQ 1700
P + L + DL + D+A GC YL + +IHRDIAARNCL++ A R+ KIGDFG+ARDIY+ +YYRK G ++LP+KWM PE+ + +T+K+D WSFGVLLWEI +LG PYP +N +V+ FV +GG P NCP + +M +CW P+ RP F L ++
Sbjct: 1219 PNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGA-GRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYM-PYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIE 1388
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|124531|sp|P15127.1|INSR_RAT (RecName: Full=Insulin receptor; Short=IR; AltName: CD_antigen=CD220; Contains: RecName: Full=Insulin receptor subunit alpha; Contains: RecName: Full=Insulin receptor subunit beta; Flags: Precursor) HSP 1 Score: 180.644 bits (457), Expect = 2.484e-44 Identity = 84/168 (50.00%), Postives = 118/168 (70.24%), Query Frame = 0
Query: 1536 TLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELL 1703
TL ++ Q+ ++A G AYL+ +++HRD+AARNC+V A D VKIGDFG+ RDIY+ YYRK G+ LLP++WM+PESL D +T SD+WSFGV+LWEI +L PY ++N V+ FV +GG+ P NCPERL +LM CW F+P RPTF + ++ +++ L
Sbjct: 1133 TLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMV----AHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAE-QPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDL 1295
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|408360149|sp|P15208.2|INSR_MOUSE (RecName: Full=Insulin receptor; Short=IR; AltName: CD_antigen=CD220; Contains: RecName: Full=Insulin receptor subunit alpha; Contains: RecName: Full=Insulin receptor subunit beta; Flags: Precursor) HSP 1 Score: 180.644 bits (457), Expect = 2.935e-44 Identity = 84/168 (50.00%), Postives = 118/168 (70.24%), Query Frame = 0
Query: 1536 TLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELL 1703
TL ++ Q+ ++A G AYL+ +++HRD+AARNC+V A D VKIGDFG+ RDIY+ YYRK G+ LLP++WM+PESL D +T SD+WSFGV+LWEI +L PY ++N V+ FV +GG+ P NCPERL +LM CW F+P RPTF + ++ +++ L
Sbjct: 1122 TLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMV----AHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAE-QPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDL 1284
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|296439447|sp|Q9UM73.3|ALK_HUMAN (RecName: Full=ALK tyrosine kinase receptor; AltName: Full=Anaplastic lymphoma kinase; AltName: CD_antigen=CD246; Flags: Precursor) HSP 1 Score: 180.259 bits (456), Expect = 4.307e-44 Identity = 82/172 (47.67%), Postives = 112/172 (65.12%), Query Frame = 0
Query: 1529 PRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQ 1700
P + L + DL + D+A GC YL + +IHRDIAARNCL++ RV KIGDFG+ARDIY+ +YYRK G ++LP+KWM PE+ + +T+K+D WSFGVLLWEI +LG PYP +N +V+ FV +GG P NCP + +M +CW P+ RP F L ++
Sbjct: 1215 PSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT-CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYM-PYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIE 1384
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|143811416|sp|P29376.3|LTK_HUMAN (RecName: Full=Leukocyte tyrosine kinase receptor; AltName: Full=Protein tyrosine kinase 1; Flags: Precursor) HSP 1 Score: 177.948 bits (450), Expect = 4.941e-44 Identity = 82/166 (49.40%), Postives = 110/166 (66.27%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQ 1700
L + DL Q+ D+A+GC YL + +IHRDIAARNCL+S RV KIGDFG+ARDIY+ +YYR+ ++LLP+KWM PE+ + +T+K+D WSFGVLLWEI +LG PYP N +V+ FV GG P CP + +M +CW P+ RP+F L +Q
Sbjct: 615 LVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSC-AGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYM-PYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQ 778
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|2497556|sp|Q25410.1|MIPR_LYMST (RecName: Full=Putative molluscan insulin-related peptide(s) receptor; Contains: RecName: Full=Putative molluscan insulin-related peptide(s) receptor alpha chain; Contains: RecName: Full=Putative molluscan insulin-related peptide(s) receptor beta chain; Flags: Precursor) HSP 1 Score: 177.948 bits (450), Expect = 2.348e-43 Identity = 78/157 (49.68%), Postives = 114/157 (72.61%), Query Frame = 0
Query: 1537 LADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFR 1693
L D+ Q+ ++A G AYL+D +++HRD+AARNC+VS ++R VKIGDFG+ RDIY+ YYRK G+ +LP++WMAPESL D +T+ SDVWS+GV++WE++ L PY ++N +V+ F+ +G ++P NCP + LM CWA P+QRPTF+
Sbjct: 1147 LLDILQMAGEIADGMAYLADKKFVHRDLAARNCMVS----EERTVKIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTLA-AQPYQGLSNEEVVKFISDGYIMELPENCPNEMAYLMQHCWAKKPNQRPTFK 1298
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|357529496|sp|Q64716.3|INSRR_RAT (RecName: Full=Insulin receptor-related protein; Short=IRR; AltName: Full=IR-related receptor; Flags: Precursor) HSP 1 Score: 175.637 bits (444), Expect = 7.802e-43 Identity = 88/183 (48.09%), Postives = 118/183 (64.48%), Query Frame = 0
Query: 1536 TLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELAEIPSFCQF 1718
L+D+ Q+ ++A G AYL+ +++HRD+AARNC+VS +D VKIGDFG+ RD+Y+ YYRK G+ LLP++WMAPESL D +TT SDVWSFGV+LWEI+ L PY ++N V+ FV +GG + +CP +L+ LM RCW P RPTF L +Q DEL C F
Sbjct: 1088 ALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVS----QDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAE-QPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHILDRIQ------DELRPSFRLCSF 1259
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|82175202|sp|Q9PVZ4.1|INSR_XENLA (RecName: Full=Insulin receptor; Short=IR; AltName: Full=XTK-1b; AltName: Full=Xe-InsR; Contains: RecName: Full=Insulin receptor subunit alpha; Contains: RecName: Full=Insulin receptor subunit beta; Flags: Precursor) HSP 1 Score: 175.637 bits (444), Expect = 9.346e-43 Identity = 85/176 (48.30%), Postives = 119/176 (67.61%), Query Frame = 0
Query: 1528 DPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELL 1703
+P RL TL ++ Q+ +++ G AYL+ +++HRD+AARNC+V A D VKIGDFG+ RDIY+ YYRK G+ LLP++WM+PESL D +T SDVWSFGV+LWEI +L PY ++N V+ FV +GG P NCP RL +LM CW ++P RPTF + + +++ L
Sbjct: 1114 NPGRLAP-TLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMV----ADDYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAE-QPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDL 1283
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|341940836|sp|Q9WTL4.2|INSRR_MOUSE (RecName: Full=Insulin receptor-related protein; Short=IRR; AltName: Full=IR-related receptor; Contains: RecName: Full=Insulin receptor-related protein alpha chain; Contains: RecName: Full=Insulin receptor-related protein beta chain; Flags: Precursor) HSP 1 Score: 174.481 bits (441), Expect = 1.892e-42 Identity = 88/183 (48.09%), Postives = 117/183 (63.93%), Query Frame = 0
Query: 1536 TLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELAEIPSFCQF 1718
L+D+ Q+ ++A G AYL+ +++HRD+AARNC+VS +D VKIGDFG+ RD+Y+ YYRK G+ LLP++WMAPESL D +TT SDVWSFGV+LWEI+ L PY ++N V+ FV +GG + NCP +L+ LM CW P RPTF L +Q DEL C F
Sbjct: 1088 ALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVS----QDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAE-QPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHILDRIQ------DELRPSFRLCSF 1259
BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Match: gi|124908|sp|P14617.1|INSRR_CAVPO (RecName: Full=Insulin receptor-related protein; Short=IRR; AltName: Full=IR-related receptor; Contains: RecName: Full=Insulin receptor-related protein alpha chain; Contains: RecName: Full=Insulin receptor-related protein beta chain; Flags: Precursor) HSP 1 Score: 174.096 bits (440), Expect = 2.506e-42 Identity = 91/204 (44.61%), Postives = 125/204 (61.27%), Query Frame = 0
Query: 1536 TLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDEL------AEIPSFCQFNPTSHPNSVSMHNSR 1733
L D+ Q+ ++A G AYL+ +++HRD+AARNC+VS +D VKIGDFG+ RD+Y+ YYRK G+ LLP++WMAPESL D +TT SDVWSFGV+LWEI+ L PY ++N V+ FV +GG + +CP +L+ LM CW +P RPTF L+ +Q+ L L E C PT+ S S S+
Sbjct: 1088 ALGDMIQMAGEIADGMAYLAANKFVHRDLAARNCMVS----QDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAE-QPYQGLSNEQVLKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRLRPTFTQILNSIQKELRPSFRLLSFYHSPECQGGCGLQPTTDAESSSPPTSK 1286
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|307166553|gb|EFN60620.1| (Proto-oncogene tyrosine-protein kinase ROS [Camponotus floridanus]) HSP 1 Score: 426.017 bits (1094), Expect = 1.077e-117 Identity = 453/1835 (24.69%), Postives = 780/1835 (42.51%), Query Frame = 0
Query: 11 LQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEER---QRPFQSMSEGILFHYNDSYYWTN-ANVLHQLMGDNRSGHFQSSF--KEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAEETNLVTCVEH---GTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLG---------TNHSRVELPFKARHVACRSGDAVLLSTDTSLLS---AQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLE---EDSKLVWRALTG--------EVTYHLLIQVHGRQYALQTTTSELDLAQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF-----------HNAVNSS--IIVRWNPPKLPNGHITGYQME---INSLDTIIVHPD------TLEQVLVEL-PSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRAT---YDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFS------------VDSGVLSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGR-IKSLKPTSTHAQCSC-FQMDPRSPFYFTLRPNIPEQKASLTLLTHDGSLFATD-NGCECQLMR---KIPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVI----------IRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQFRAP--CTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPT--ELIALAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSR-----IPSGHRQKPTEKEFSVELKDLEPGEIYKIWVEARTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRS--PPIKAIQAF--QFRLVPLKSNLNASQYQWPMELS---SIQPGHQYQ--GQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW---NSNNDLVESFELQARIHDSNVTVEDNVTMSN--WSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVL------------VVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNG-GMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQVQCRDPRRLLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
+++D NG +FW ++ + D S+ + I+ LG+ +D + RLLV + ++ L D+ F++R Q P + + N +YWTN ANVL + + +F + + + D + + QPIPVP+NP V+ G + A++ W+ S +Q W+Y++ + +S E + Q + L V H + ++ A + G+ WS ++L +G +L W + +SD+ G TN E F V+ ++ +++L + Q+ + + + S+ +Y PK I R S +E + + VK L +DSL A L W G ++ + L G + R ++++ + L +D +++ R S +++++ + IP+ + V++L+ G + Y+ + L W+QDG V DL GQ+ + I L G + D + P+ + + + ++P VD++S+++E + + W + EV + I + TT + + +I P + + VT+ A + W + K L +P + + P RAF H + + +I RWN P+ NG I Y ++ I + + I + D TLE + L + + +R G SP + L+ + +PQ+L+ + DLD R I T + + L+F+ S+ + + ++L L +DW++ +++ + ++ R S V +N+ I +++ P +LY+ + + + ++ L GR ++ + + C+C F P + NI QK + ++ +G L D GC C ++ K + L+ D N+YW + + +++ N + ++ I I F Q P +CL+P + + A + V+LP+ C N SLP + I+ E +G +LQ E ++ I++L+PFT Y + L L Q +PT L + T G+P PEN T L P V W+PPK+ N + Y+VH+ ++ SR + Q + F LK P + Y+++V + + E +T + S P T + RSV + S P I ++ Q++ V L + W + + ++ QY+ I++L P T Y + +L + +IWP D +R +T D P PG+P V ++ S L W ++ V ++L+ I D+ +DN N W++ Y T W I G D FRVRAKN +G+ +SE + I L S+ GL + + G++ I+ ++ + V I LR+ + + L H+ + L G ++++P + + E D+ R L Q D R L L DL +C DV +GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVL+WEI +LG+ PYP NL+V+ +V GG P NCP L LM+RCW D RP+F+ CL + L
Sbjct: 341 IEVDPYNGYIFWVVKEGLFKLDLADISNGVKHEVQPYLILKDGNLGAFTVDHMNFRLLVAHHRNNTVIALPFYGRDY-------FDQRPNIQTPIFNHVVSLAMA-NGLFYWTNGANVLTEGYHHEQKKYFHNFYLDRSDTNFISVNVLMNASQPIPVPVNPPTGVQAVLG------AEKAKISWQAPHLLGSQGKGAYQNWSYELEIIDESTGETIHQKDIVGLSHTVYHLREKSKYSIKAAAYTNAGRGPWSAEFRGRTLTDGSHASIL-WSSNEGLLRSDVTGENIDTLISKTNLRESESEFHIVDVSWYKDVLYIVGNNSALYCYNVSTHQLTRLITHSVGSVAVDWLSKKLYWANPKQQIITRANLNGSQQEPMILAI--VKELMIDSLEAYLYW-STGHAVEVARLNGQNRRYYHSDEIFNGKQVMGLTLDTENRYVYWIVRSYESGSIVYRAPTSE-RIPMNHQIVPEKVSVLKDPNVQGPVCYFSEHLLWLQDGTNAVIGDLSGQNTAVINGITLSGLHMVAVMDPALHQYPKNLTSETVMVSPNAVDINSIRVEGTWRNFNISWDPVENINYGTVFYEVKFADYINTNSNPEITNETTIPYNNSDQIL---PYSVLEVTVKAFTYWESAHNSRKILKSPESMPTQPMFPRAFVDKEFHHEFRHHEFITNDRLVIFRWNQPQFTNGVIERYMVQCWFIENQNRIQICNDQNIPASTLEYTVHNLRRNMTYYFQVRAYTKIGPSPYTDLINVSTTYENPVPQLLV---ATADAVRMSDLD-REINYTLTRHSATDVNYLEFENEIYWISEMQELVTSEINGANATKILALKNSAHSLCIDWVARNLYWTEYNSTNSYNRENSGYIMKLDLTMWKVGEVKYNNIVKRGRYIPVLDILPSLRSLYWIEAINDRGII--MQSDLDGRNVQPFFKNNVNKTCTCPFSSLSVMPMMTVDKTNI--QKPMIYWVSMEGHLNVADIYGCMCNVVYADFKTATLTSLTVDKVNIYWANATENRIYFMKKEYPFSMNKENMSKPEIKSVYLSNVRHIIAFGKSLQTYPATKCLIPRRKAYTIERVNATATSIVVNLPETNPEIGCENYSLPSTLYVIHVRCQECEG-------------------FELQT-----YERHYE--IQNLKPFTNYTLQLILSNVYIKQYKLPTLSGLDVVLMTDPGKPYAPENFTVQVLTPTLAAVYWMPPKILNCAAVHYEVHWISPLLVNGSRHKGEQVMKDKLQLTKDGRFFTMLKPFLPNQEYQVYVRVYPVNFTNLYN-ETLKKTINMYSEPNNLTLSERSVNSMNISWIPSINLTISYTLQYKDVSLDTRCPMQNCDWQIADNFEKALTELKQYKITYHIRNLQPRTLYKFRLILKY--STYAEDFIWPSD-ERFTFQTLGDVPSAPGKPTVT-RLRNSVYQLNWEPAQAHGSQVTLYQLEGLITDN--YKQDNEATENEYWNLYYNGTDNYWIIPGDIDQYVKFRVRAKNAYGFGAWSESSSI--IDLTESAGGLINITAQQHLPFMLGLIVIVIIVFQGVAKDLEGPGITPVAIKMLRKDASSQEKTEFLQEARLMSHFRHKHVLRLLGVCLDTDPP--LLVLELMEAGDLLSYLRENRAL------------QPTDSR---ALRLQDLLAMCEDVVRGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGIFTSQSDVWAFGVLIWEITSLGQ-QPYPARTNLEVLHYVRAGGRLPKPLNCPATLHQLMMRCWD-TADARPSFKICLENIVAL 2091
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|1316174817|ref|XP_023232900.1| (proto-oncogene tyrosine-protein kinase ROS-like [Centruroides sculpturatus]) HSP 1 Score: 389.037 bits (998), Expect = 7.561e-106 Identity = 465/1914 (24.29%), Postives = 813/1914 (42.48%), Query Frame = 0
Query: 10 DLQLDSVNGNVFWHTGNEIWTVSKCDPSSSKRIVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNANVLHQLMGDNRSGHFQSSFKEDIDLRTSVFH-----HPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAEETN---LVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEG--PTDLVLTWIRKGQVFQSDLLGTNHSRVELPFKARHVACRSGDAV---------LLSTDTSLLSAQGQILFKANAEISGLLFEPFSESVYTMVPK--SDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFFTRKDG------SQTVIHQMDLEDLSIPVQVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTILLGGRGG----RITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLE---EDSKLVWRALT----GEVTYHLLIQ----VHGR------------QYALQTT---TSELDLAQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQIS---------SPPQHLRAFHNAVNSSII-------VRWNPPKLPNGHITGYQMEI----NSLDTIIVHPDTLEQVLVE------LPSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDVGAIQTLDFQGPKAV--FSQGGSIFALNLINHVRERVLTQAEL------ILH--------LRVDWISNCIFFVAVSGSDY-SIRRFSVDSG----VLSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLE---------LSLFGRIKSLKPTSTHAQ------CSCFQMDPRSPFYFTL-RPNIPEQKASLTLLTHDGSLFATD-NGCECQLMRK--------IPAWSQLSSDGSNLYWKSHEFVQYLNLQEG------------------QISHFNGSSRNEGVI-IRPFCPDCQMTPIKQCLVPSLVEQRV-TILEAGEDWLRVSLP--QFRAPCTN-SLPQVEFTIYYYVIESQGHSELPSITPE-SCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIALAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEKEFSVELKDLEPGEIYKIWVEA-RTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQ-AFQFRLVPLKSNLNASQYQWPMELSSIQPGHQ-YQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWNSNNDLVES--FELQARIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGL-SDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIV----------GIIGVLVVVV------LIIFLRRPWDKKSALGIQR-----HRELELATIHELPVMLNGGMES-NPTYGVQIPSEQEMEDIPKL-------KRNQITLVNFIGCGAFGQVQCRDPRRLLK--LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQELLVYEDELAEIPSFCQFNPTSHPNSVSMHN 1731
DL +D +G VF ++I ++ + + I+ L + ID+ + R+L+ + + ++ L D +++ + F ++ L ++N+ +YWT ++ G+ ++ ++ + H + QP PVPLN V V+ F A++ W N WQ+W Y+I L +F N + + T ++ +RA S GGK EWS ++L + P + W + + +SD++G N + K + + +L D + N+ I+ + + + P+ + EI R + E L I K L +DS L W S+ S+L G + ++ ++S + L ++ ++++T ++ S + + + ++++ L + G L Y+ D+L WI + + + D+ G++ + G I D +Q P + D+++ P ++ + +E + +VW ++T G++ Y + + ++G +++L+ + +A E + AA+ +KS + P +S S P++ R F +S + RW+PP NG + GYQ+ + T + H T++ +++ LP+ + N G+ S ++ + +P++L+ ++ ++ DLD A + + + ++ P AV ++ IF L+ + R L + + ++H L +DWI +++ + Y SI + + S + N + T D I E++P T L ++ + K+ L + + SL S K Q CS R+ FT+ R NI + L + +DG ++A+D NGC C+++ +P + +++D + +YW ++E ++ + Q F +GV I Q P +CL PS E + +L++ + L++ LP CT+ SLP ++TIYY SE+ +C + S C+ ++ ++ L+PFT Y I +++ ++ I QT +G P P+N+ + PE ++V W P NGK + Y+V +++ + + H +K EK ++LK+L PG Y I V A +G S E+ A+T+ + + + ++ F W SP IQ + + +P + W L Y I++L P T+Y ++ VLT+ + +Y+WP+D+ +I+ ET +P IPG PYV + V + W E+ + L+++I ED S W +VY T QW L Y FRV+A N++G S FS + P + L+S L +G + + A I+ GI+G + V + +I+ L D + L R L L + + V + G + + V S + E I +L N I L G ++ P L L DL IC DVAKGC L +M ++HRD+AARNCLVSS D R+VKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T +SDVW+FGVLLWE+M LG+ PYP NL+V+ +V GG P NCP+ L LM+ CW+++P+ RPTF CL +++EL + I S N H ++ + N
Sbjct: 345 DLHVDPFHGFVFLVDLHDI-SLKPAFENDIQLIIKDYNLETFTIDYMNFRILIPNATLNTIIATSL---DGTDSIDIRYNSHSPHFSNVKS--LTYHNNLFYWTTGTSIY---GEEYHSKVDKYYRNKFLIKANYISNVKVLHIDSQPYPVPLNEVENVQALFQ------DETAKIFWSKPKLLNDVGKGAWQKWFYEIHLFDHVKNLTIFGNRTANNIYKIFTLRPNTTYSIKIRACSLGGKGEWSSEFVGKTLMQNNSPGYPYIIWSSREGIIKSDIIGENVEPLIYNIKLDEIGVTVKGELTDINVIPDSILEKDIWVEGMWNNFTIVWNS-ITNVNYGDIFYEIKLNGPEDINGEISRANLDGTQPESLSINTLAEK-LVIDSPSGHLYW-STTHSVEGSNLNGDNTYTYMQTGVFSGKRVMGLTLNYDQQKIYWTIRNYEGSWLYSAKTLKNVFGRNKDDVIELIAQLPENAIQGPLWYFSDRLFWINEEKEALISDMSGRNVACFKHVGLKDLETLTIIDPALQPYPMKGELTDINVIPDSILEKDIWVEGMWNNFTIVWNSITNVNYGDIFYEIKLNGPEDINGEDPVEWRLFIDLLKFSLKGVLPYNGNKHSSVPVAHAVHIKETYNNMKAAAEHNKSWVICDAQQLPKCLSTDAVNVLNPSSPENPRIFIMYKSSFLFPNDIEAEFRWSPPLHINGILLGYQINCWHMKENKSTSLCHNVTVDGSILKYKLKNLLPNCTYSFQVAAYNVIGIGTFSDIVKTHTSQENPIPKLLL---VKTDTVEMTDLDT----AEEHLLSNKIIE---PVAVTYLAKDDKIFWLD-----KNRALMSSHMDGSNTALIHSLSSPGTSLTIDWIGRYLYWAEHENNYYDSIWKLDITSSQAPHFILNYSSTIDSI---EVEPFTRKLIWSAMKQDKYNLMRSDTNGQNIENFFSLSNNCHSSKSDIQRNQIGHSYNCSSSLFVRRA---FTIDRSNISHPEL-LWVDGNDGHIWASDLNGCNCRILVNANENKNIGLPP-TSITADTTAIYWFNNESGGIYSMNKNSKFQNPPTPPPKLPTSASQKRRFQLIKEIQGVKQIYAIGSHLQSYPDIKCLYPS--ESGIPQLLDSSFNSLKLQLPLISHSKDCTDISLPTFQYTIYY--------SEVNKFNKIINCEFNISHCIIMKT-------YDDIIVLTGLKPFTTYMIQVAINNYY-NKGNITLGPTVTYQTKEGVPSAPDNIIVVPVSPEQLDVYWNPSIRFNGKSVSYEVRWKVDYSGDQFNLDT-HARKAHEKCM-MKLKNLLPGTKYYIVVRAYSSGEDLYNDSQEVTAKTYDQPNNLTLLETNEENLKFSWLSPSDGVIQHSLEITELP--------DFNWHEVLKQETSEETVYNFTIENLYPRTKYSVRLVLTYV--ENNVSYVWPKDT-QIIYETLGKSPNIPGIPYV-QNVGRDLYQVVWTEPFPFDENTIYHLESKIFK-----EDESDYSQWKLVYNGTVNQWLTENLLPKFYYQFRVQAINDYGESNFSNASQPF---MALNSIALANQTNGQITVILASILPTLFFIASSLGIVGYIRVCLNNNPNFIILELMEGGDLLTYLRSHRPSIFTSNPLNLEDLLSICVDVAKGCKCLEEMHFVHSFSNFKHEHILQLLGVCLNNNPNFIILELMEGGDLLTYLRSHRPSIFTSNPLNLEDLLSICVDVAKGCKCLEEMHFVHRDLAARNCLVSSHDPFTRIVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTNQSDVWAFGVLLWEVMTLGQ-QPYPARTNLEVLHYVRIGGQLDKPQNCPDDLHQLMVMCWSYYPENRPTFDYCLEKLKELHRKSTSASHIDSVHNHNYLGHIHNGGIEN 2176
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|1008429184|ref|XP_015840704.1| (PREDICTED: LOW QUALITY PROTEIN: proto-oncogene tyrosine-protein kinase ROS [Tribolium castaneum]) HSP 1 Score: 330.872 bits (847), Expect = 1.038e-87 Identity = 393/1633 (24.07%), Postives = 687/1633 (42.07%), Query Frame = 0
Query: 10 DLQLDSVNGNVFWHT-GNEIWTVSKCDPSSSKR-------IVHRAKLG--SMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGI--LFHYNDSYYWTNANVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEI-----QPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAEETNL----VTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTN------HSRV------ELPFKARHVACRSGDAVLLSTDTSLLSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFFTRKDGSQTVIHQMDLEDLSIPVQ---VVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTILLGGRGGRITDLCVQGAPRQMVPQ--DLDITPLTVDLDSLKL---EEDSKLVWRALT----GEVTYHLLIQVHGRQ-YALQTTTSELDLAQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF----HNAVNSSIIVRWNPPKLPNGHITGYQMEINSLDT---------IIVHPDTLEQVLVELPSQQLH-IDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRR----IRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFS-----VDSGV--LSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELS----LFGRIKSLKPTSTHAQCSCFQMDPRSPFYFTLRPNIPEQKASLTLLTHD--GSLFATDNGCECQLMRK------IPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVP-SLVEQRVTILEAGEDWLRVSLPQFRAPCTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIALAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQK----------PTEKEFSVELKDLEPGEIYKIWVEARTGSSKV-AQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW----NSNNDLVESFELQA-RIHDSNVTVEDNVTM------------SNWSVVYADTSPQWPISGLSDA-AYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKS--ALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
++++D NG +FW G ++ + D S+ R I+ KL + +D + RL V + + ++ V D +I+N+ R +S E + L N +YWTN + + N S +F +S+ D+ L T + I QPIP P+NP V+ FG+N +A+ W P WQ W+Y++ ++ + ++K N ++ + T + A + G+ WS +L ++ W + ++D G N SR+ ++ + V + D+ + DT S QGQ++ + + + + +Y PK I+R + +E L I K L++DS+ A L W G ++ C+ L G + + L+S + L +D +++ + + + + + S + +T L+ G L Y+H +L W+QD DL G + +TI G +T + V + ++P ++ + P TVD +S+++ + W + G+V Y + I R A+ T ++ + Q++A P T+++V + A + W SPQ+ +++P S P +LRA+ + N +I VRW PP PNG + GY++ L+ ++ P+ Q+ + P ++ +++ + G S + N LP++L+ + D+D R + I L + Q ++ +++ + ++ + + + VDW+ I++ D F VD G+ +S V T I +E+ P T LY+ + K + + S F + K K ++ C+C +D +TL + E K L + D + A NGC C ++ +P +L SD LYW + + L +E + + R+ I F P Q P +CL P L RVT+ E L + +P+ C + S+P VE+ IYY I +C L + +F IK L+PFT Y + +++ ++ I + QT G P PP+NVT L+P +V+W PP+ NG VHYE++ T R SG RQK P ++ L L P E Y IWV+A + +++ + S +++ T+ S + RT +T W I + ++ P+ SN W + + G ++L P TQY + L++ YIWPQDS R + ET D P PG P + + + +Y W N +E ++L+ + + N T W Y T W I+GLS+ Y FRV A N +GWS S+ + ++ +++ + + TLI ++ I + V ++++L I R+ K + I R ++ELAT+ ELP G +N Y P+ +EM +P ++R+QITL+ F+G GAFG+V
Sbjct: 464 NIEVDPYNGYLFWGIHGTGLYRLDISDFSNGIRHEVQPVLILSEKKLNMSAFTVDHTNFRLFVANEREK---TINTVSLDGKEIINV----RPNVIKSKLENVVSLATANKKFYWTNGDDIFYEEYHN-SVYFHNSYP-DLSLSTKSYKKVIINLQSSQPIPSPVNPPTNVQAIFGSN------IAKTTWLPPHLLGIQGKGAWQNWSYEVAIK-EVGSQKFISHRNINTTSYKISGLRENTEYVIKAAAYTRSGQGPWSSEFRGFTLSRSKNPMIY-WSAAKGLLRTDAAGENVETLIHKSRIKGSVFIDMTWYQDLVYLVTNDSHVYWYDTRSHS-QGQLI--GIDSVGSIAVDWIGKKLYWSNPKRQMIIRGNLNGTQQEPLPILTLA-KELNIDSVKAYLYW-STGFAVRCAHLNGENLIEYHPVQLFSGRQVMGLTLDMHNKFVYWIVRGLEGSNLFRAPMAGYSEKITENFKITSLQKPNMQGPLCYFHKRLLWLQDNKNAAISDLQGNNIATIS-GKSMSDLTLVYVVDSSLHVMPDIPEIVVIPETVDKNSVRVIGSLNSFNVTWNPVKNVNYGQVFYEVSIDSLLRNDSAIVTNSTSVRYWQQVA---PFTKLQVAIRAFTYWGTSPQIRAKVYSPASTPSVPTNLRAYVTHHSSGTNVTITVRWGPPLFPNGVLKGYKIHCWYLNAAQRRDVCRDLVKKPEEF-QIDFKPPHDHIYYFNVQAFSEMGDGDLSDPIQVNSSQELPLPRLLV---ASEDSIFIQDIDSDRNESLLHGIVTPTEIGYLIKESKLFWIDQLQNLMMYDMLKGNKTKITSLRNNVTGVTVDWLERSIYYAQSENWDSGSSVFKLDLNYVDRGIVKMSKVFFTPASISKIEVSPYTRKLYW--VEKSKLMVCNTDGSDKSEFFNKNKYTKRSTLGGGCNC-PVDVNIEKTYTLDHST-ETKPLLVFVESDTQNVVSADKNGCSCSVIANNSLGVTLPL-DRLKSDFGTLYWTNSRLLHALRKKEANLVTKEVNGRD----ILIFGPHMQPFPPSECLRPRQLANIRVTLKEKTATSLTLVMPEVGQICADTSMPTVEYRIYY----------AEKIDNNTCD--------LTCNFSATFDKEFT--IKSLKPFTHYVVAVAVSNYYTEEEEIVLGPSTVFQTAVGAPSPPQNVTVKVLNPTMAQVSWSPPQHPNG----VTVHYEIY--CQTERTLSGVRQKEQSNVEQQFTPNSHFLTIVLNKLSPNETYTIWVKAYSETNETSSDSDKVQINTYPEPSDLILVNRTAYMLTVTWDV--CANIDHYNVQMSPVTSN------DW---RNVSESGEGIFASEENLQPKTQYKFRLSLSYY--NYPEEYIWPQDS-RFVYETLGDKPSPPGTPKI--QYVKPNIYKVWWEEAKDNGAPIELYKLEGLELPNYRTKRSTNRTAFFYTAPSVEEEEREWQQFYNGTETSWIINGLSEKYKYEFRVLALNAYGWSDPSDSSTAFDLN--EAARMAEKQSPMTLIAIATFIP--VSVFLIILLCIVCRKYGKPKKVQVVSIPRGPDVELATLRELP--RRGIHNTNVLYVSTQPTSEEMTLLPHIRRDQITLMKFLGSGAFGEV 2009 HSP 2 Score: 228.409 bits (581), Expect = 4.201e-56 Identity = 103/168 (61.31%), Postives = 129/168 (76.79%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
L+L +L ++C DVAKGC YL +M ++HRD+A RNCLVSS D DR+VKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVLLWEIM LG+ PYP NNL+V+ +V GG P +CPE L NLML+CW F D+RPTF+ CL + L
Sbjct: 2100 LSLIELLKMCVDVAKGCRYLEEMHFVHRDLACRNCLVSSKDP-DRIVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLLWEIMTLGQ-QPYPARNNLEVLHYVRRGGRLGKPTDCPETLHNLMLKCWEFEADKRPTFKYCLDVLDNL 2265
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|1004403084|gb|EEZ99293.2| (sevenless [Tribolium castaneum]) HSP 1 Score: 330.487 bits (846), Expect = 1.088e-87 Identity = 393/1633 (24.07%), Postives = 687/1633 (42.07%), Query Frame = 0
Query: 10 DLQLDSVNGNVFWHT-GNEIWTVSKCDPSSSKR-------IVHRAKLG--SMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGI--LFHYNDSYYWTNANVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEI-----QPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAEETNL----VTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTN------HSRV------ELPFKARHVACRSGDAVLLSTDTSLLSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFFTRKDGSQTVIHQMDLEDLSIPVQ---VVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTILLGGRGGRITDLCVQGAPRQMVPQ--DLDITPLTVDLDSLKL---EEDSKLVWRALT----GEVTYHLLIQVHGRQ-YALQTTTSELDLAQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF----HNAVNSSIIVRWNPPKLPNGHITGYQMEINSLDT---------IIVHPDTLEQVLVELPSQQLH-IDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRR----IRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFS-----VDSGV--LSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELS----LFGRIKSLKPTSTHAQCSCFQMDPRSPFYFTLRPNIPEQKASLTLLTHD--GSLFATDNGCECQLMRK------IPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVP-SLVEQRVTILEAGEDWLRVSLPQFRAPCTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIALAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQK----------PTEKEFSVELKDLEPGEIYKIWVEARTGSSKV-AQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW----NSNNDLVESFELQA-RIHDSNVTVEDNVTM------------SNWSVVYADTSPQWPISGLSDA-AYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKS--ALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
++++D NG +FW G ++ + D S+ R I+ KL + +D + RL V + + ++ V D +I+N+ R +S E + L N +YWTN + + N S +F +S+ D+ L T + I QPIP P+NP V+ FG+N +A+ W P WQ W+Y++ ++ + ++K N ++ + T + A + G+ WS +L ++ W + ++D G N SR+ ++ + V + D+ + DT S QGQ++ + + + + +Y PK I+R + +E L I K L++DS+ A L W G ++ C+ L G + + L+S + L +D +++ + + + + + S + +T L+ G L Y+H +L W+QD DL G + +TI G +T + V + ++P ++ + P TVD +S+++ + W + G+V Y + I R A+ T ++ + Q++A P T+++V + A + W SPQ+ +++P S P +LRA+ + N +I VRW PP PNG + GY++ L+ ++ P+ Q+ + P ++ +++ + G S + N LP++L+ + D+D R + I L + Q ++ +++ + ++ + + + VDW+ I++ D F VD G+ +S V T I +E+ P T LY+ + K + + S F + K K ++ C+C +D +TL + E K L + D + A NGC C ++ +P +L SD LYW + + L +E + + R+ I F P Q P +CL P L RVT+ E L + +P+ C + S+P VE+ IYY I +C L + +F IK L+PFT Y + +++ ++ I + QT G P PP+NVT L+P +V+W PP+ NG VHYE++ T R SG RQK P ++ L L P E Y IWV+A + +++ + S +++ T+ S + RT +T W I + ++ P+ SN W + + G ++L P TQY + L++ YIWPQDS R + ET D P PG P + + + +Y W N +E ++L+ + + N T W Y T W I+GLS+ Y FRV A N +GWS S+ + ++ +++ + + TLI ++ I + V ++++L I R+ K + I R ++ELAT+ ELP G +N Y P+ +EM +P ++R+QITL+ F+G GAFG+V
Sbjct: 18 NIEVDPYNGYLFWGIHGTGLYRLDISDFSNGIRHEVQPVLILSEKKLNMSAFTVDHTNFRLFVANEREK---TINTVSLDGKEIINV----RPNVIKSKLENVVSLATANKKFYWTNGDDIFYEEYHN-SVYFHNSYP-DLSLSTKSYKKVIINLQSSQPIPSPVNPPTNVQAIFGSN------IAKTTWLPPHLLGIQGKGAWQNWSYEVAIK-EVGSQKFISHRNINTTSYKISGLRENTEYVIKAAAYTRSGQGPWSSEFRGFTLSRSKNPMIY-WSAAKGLLRTDAAGENVETLIHKSRIKGSVFIDMTWYQDLVYLVTNDSHVYWYDTRSHS-QGQLI--GIDSVGSIAVDWIGKKLYWSNPKRQMIIRGNLNGTQQEPLPILTLA-KELNIDSVKAYLYW-STGFAVRCAHLNGENLIEYHPVQLFSGRQVMGLTLDMHNKFVYWIVRGLEGSNLFRAPMAGYSEKITENFKITSLQKPNMQGPLCYFHKRLLWLQDNKNAAISDLQGNNIATIS-GKSMSDLTLVYVVDSSLHVMPDIPEIVVIPETVDKNSVRVIGSLNSFNVTWNPVKNVNYGQVFYEVSIDSLLRNDSAIVTNSTSVRYWQQVA---PFTKLQVAIRAFTYWGTSPQIRAKVYSPASTPSVPTNLRAYVTHHSSGTNVTITVRWGPPLFPNGVLKGYKIHCWYLNAAQRRDVCRDLVKKPEEF-QIDFKPPHDHIYYFNVQAFSEMGDGDLSDPIQVNSSQELPLPRLLV---ASEDSIFIQDIDSDRNESLLHGIVTPTEIGYLIKESKLFWIDQLQNLMMYDMLKGNKTKITSLRNNVTGVTVDWLERSIYYAQSENWDSGSSVFKLDLNYVDRGIVKMSKVFFTPASISKIEVSPYTRKLYW--VEKSKLMVCNTDGSDKSEFFNKNKYTKRSTLGGGCNC-PVDVNIEKTYTLDHST-ETKPLLVFVESDTQNVVSADKNGCSCSVIANNSLGVTLPL-DRLKSDFGTLYWTNSRLLHALRKKEANLVTKEVNGRD----ILIFGPHMQPFPPSECLRPRQLANIRVTLKEKTATSLTLVMPEVGQICADTSMPTVEYRIYY----------AEKIDNNTCD--------LTCNFSATFDKEFT--IKSLKPFTHYVVAVAVSNYYTEEEEIVLGPSTVFQTAVGAPSPPQNVTVKVLNPTMAQVSWSPPQHPNG----VTVHYEIY--CQTERTLSGVRQKEQSNVEQQFTPNSHFLTIVLNKLSPNETYTIWVKAYSETNETSSDSDKVQINTYPEPSDLILVNRTAYMLTVTWDV--CANIDHYNVQMSPVTSN------DW---RNVSESGEGIFASEENLQPKTQYKFRLSLSYY--NYPEEYIWPQDS-RFVYETLGDKPSPPGTPKI--QYVKPNIYKVWWEEAKDNGAPIELYKLEGLELPNYRTKRSTNRTAFFYTAPSVEEEEREWQQFYNGTETSWIINGLSEKYKYEFRVLALNAYGWSDPSDSSTAFDLN--EAARMAEKQSPMTLIAIATFIP--VSVFLIILLCIVCRKYGKPKKVQVVSIPRGPDVELATLRELP--RRGIHNTNVLYVSTQPTSEEMTLLPHIRRDQITLMKFLGSGAFGEV 1563 HSP 2 Score: 229.18 bits (583), Expect = 1.973e-56 Identity = 103/168 (61.31%), Postives = 129/168 (76.79%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
L+L +L ++C DVAKGC YL +M ++HRD+A RNCLVSS D DR+VKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVLLWEIM LG+ PYP NNL+V+ +V GG P +CPE L NLML+CW F D+RPTF+ CL + L
Sbjct: 1654 LSLIELLKMCVDVAKGCRYLEEMHFVHRDLACRNCLVSSKDP-DRIVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLLWEIMTLGQ-QPYPARNNLEVLHYVRRGGRLGKPTDCPETLHNLMLKCWEFEADKRPTFKYCLDVLDNL 1819
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|817083237|ref|XP_012264218.1| (proto-oncogene tyrosine-protein kinase ROS isoform X2 [Athalia rosae]) HSP 1 Score: 330.872 bits (847), Expect = 1.220e-87 Identity = 395/1651 (23.92%), Postives = 711/1651 (43.06%), Query Frame = 0
Query: 11 LQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNA-NVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAE---ETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSL--PEGPTDLVLTWIRKGQVFQSDLLGTNHSRV---------ELPFKARHVACRSGDAVLLSTDTSL----LSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEED-SKL------VWRALTGEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQM---------EINSLDTIIVHPDTLE-QVLVELPSQQLHIDLRCQNNAGLSPASTLL-IQNRFVLPSLPQILIYQGIQGGKLD---FYDLDRRRIRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVL-----TQAELILHLR-------VDWISNCIFFV------AVSGSDYSIRRFSV---DSGV--LSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRP-----NIPEQKASLTLLTHDGSLFATD-NGCECQLM------RKIPAWSQLSSDGSNLYWKSHE-----FVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQF--RAPCTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLI--KDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPS----GHRQKPTEKEFSVELKDLEPGEIYKIWVEARTGSSKVA--QSAEIEAQTFSRVSLPEITTRTPRSVTFIWR-SPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWN---SNNDLVESFELQARI-HDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAG-IVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQVQCRDPRRL 1532
+++D NG +FW + ++ + D S+ + I+ A L + +D + RLLV Q+ ++ + L D ++ NL +Q F+++ L N +YWTN ++L + + +F +S+ + + +V QP PVP+NP V+ G + +A+V W WQ W+Y++ ++ S E + Q E ++ V + + + A + G+ WS +L P+G + + W + +SD+ G N + ++ + VA L+ ++ L +++ N+ + + + S+ +Y PK I R + +E + I A VK L +DSL A L W G ++ S L G R ++++ + L +D +++ R S +V+++ + IP+ + ++ L+HS G L Y+ + L W+QD V DL GQ+ + I L G + I D + P+ + +++ + P V++DS+++ + SK V G V Y + H A T E +A + +P + VT+ A + W S K L +P S P + R F + + SI+ RW+ P PNG I GY + +I D I V P LE +V L + + ++ G + ++ I F P +PQIL+ LD DLDR AI+ ++ IN ++E V+ + A IL L VDWI+ +F+ V GS I R + ++G + + T +++ PL LY+ + + ++ L G ++P HA+ CSC PF +RP N + ++ +G+L D GC C ++ + +P S L+ D N+YW + + F+ LN + +I F+ S ++ Q P +CL+P V V ++E + +++ LP+ C LP +T+Y +E P C + + +V +Q ++ LI K+L+PFT+Y + L ++ EL + +T G P PENV AL P + W+PPKV NG + Y++H+ +++ R + ++P + + S L+ L PG+ Y ++V A + S + +S + + + + +T ++ S+ W + I + ++ +V L+ +W + +S++ + + I++L P T Y Q L R +IWP D+ R ET D P PG P + K+ S ++W ++ + + L+ R+ DSN+ E+ S W++ Y T W G + Y FRV+A+N +G+ ++SE + +++ +S + + + G ++GLS I+G++ + V L ++ +R DKK + ++ELAT+ E+P ++SN Y I ++ + +PK+KR QITL F+G GAFG+V D + L
Sbjct: 465 IEVDPYNGYLFWVRKDGLFRLDLADISNGIKHETHPDLILEDAHLEAFMVDHRNFRLLVPHHVQNTVISVTL---DGREVSNLRANTQQPKFKNVVS--LAMANGLFYWTNGQDILKEDYHPGQDRYFHNSYPDRSCVSVNVLMDAS-QPAPVPVNPPTGVQAVLGAH------MAKVSWRAPYLLGGQGKGAWQNWSYELEIKDVSTGEPIHQEEIGGSSHTVYHLRERSEYLIKAAAYTSAGRGPWSSEFRGCTLRDPKGGSYASILWSASEGLLRSDVTGENVETLIQKSSWKDSDMEYHIIDVAWYKDLLYLVGNNSMLYCYNMTSHETYRLHINS-VRSVAVDWISKKLYWANPKQQIITRANLDGTQQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVSRLNGQDRRYYHSDEIFNGKQVMGLTLDTENKSVYWIVRSYESGSVLYRAPTSE-RIPMNQEIVPEKLSALQHSNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLQMVAIMDHALHQYPKNLSSENITVLPSAVNVDSIRVVGNWSKFNVSWDPVRNTNYGTVFYEVKYADHINTNANPEITKETTIAYNNSERFSPYAILEVTIKAFTYWGMSHHTRKILRSPQAEPSHPTNPRGFVEFNKKPLSDDTDISIVFRWDQPDHPNGLILGYTIVCWYMKDDTKITICDKINVPPKNLEYKVDKVLSNTTYYFKVQAHTIVGAGWFTDVINISTEFEYP-VPQILV------ATLDAVRISDLDRGINDTITRHIAIEVAYSAAENKIY----------WINEMQEMVIADIDSSNATKILALNNSASSLCVDWITRTLFWTESEYRETVVGS--QIMRLDLTAWEAGYTKVEKIITTNRAASKLDISPLMGILYWIESSQNDRGI-IMQSDLHG--DDIQPFFNHAEDCSC-------PFAPLVRPVMAVDNTDIHNPVIYWVSQEGNLNIADIEGCVCNMVLSPDSGKGLPPTS-LTVDKVNVYWSNIDQDQVYFINKLNPDDTEIKKFHLYSARS---LKAIGNSLQPYPFAECLIPRQVSYNVELIEKFANSIKIKLPEPVPHFGCDKFHLPATLYTVYI--------TECLVNDPRDCKN------RERVRVQS-----YEKLIEAKNLKPFTKYMFQVGLSNYYSELESSTLELGPGNIIRTDAGAPTRPENVVVQALTPTLASINWMPPKVLNGAVVRYEIHWRSAQLVNGIRQKGEQLIKNTEQPADGKLSAMLQPLLPGQEYLVYVRAYSAHSTTSYNESVPLSVRMYPEPNNLTLTGQSINSMNVSWAPNESITIVYHLEYSIVGLE--------KWQIATNSVKRNDKVEFIIQNLRPRTLYRFQ--LVLRYPNYNQDFIWPADA-RFTFETSGDVPSAPGIP-ISTKLRGSVHQISWEPAQAHGSQITLYRLEGRVVEDSNLVEENRNDTSQWNLYYNGTDASWISVGEMNQKYQFRVQARNAYGFGKWSEISGVVDLTEAVSGILVARQHLGLVLGLSVPLILGVMLLCFGVFLCLYRQRKEDKKVVIP-PTMPDVELATLREIP--RGNFVQSNALYASAIQNDPDDSALPKIKREQITLAKFLGSGAFGEVFQGDAKDL 2032 HSP 2 Score: 209.92 bits (533), Expect = 1.896e-50 Identity = 96/168 (57.14%), Postives = 123/168 (73.21%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
L L DL +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVL+WEI +LG+ PYP NL+V+ V GG P NCP L LMLRCW+ D RP+F+ CL + L
Sbjct: 2115 LRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLYHVRAGGRLPKPLNCPTALHQLMLRCWST-ADARPSFKACLDHIITL 2280
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|817083241|ref|XP_012264220.1| (proto-oncogene tyrosine-protein kinase ROS isoform X4 [Athalia rosae]) HSP 1 Score: 327.02 bits (837), Expect = 1.976e-86 Identity = 395/1654 (23.88%), Postives = 712/1654 (43.05%), Query Frame = 0
Query: 11 LQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNA-NVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAE---ETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSL--PEGPTDLVLTWIRKGQVFQSDLLGTNHSRV---------ELPFKARHVACRSGDAVLLSTDTSL----LSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEED-SKL------VWRALTGEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQM---------EINSLDTIIVHPDTLE-QVLVELPSQQLHIDLRCQNNAGLSPASTLL-IQNRFVLPSLPQILIYQGIQGGKLD---FYDLDRRRIRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVL-----TQAELILHLR-------VDWISNCIFFV------AVSGSDYSIRRFSV---DSGV--LSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRP-----NIPEQKASLTLLTHDGSLFATD-NGCECQLM------RKIPAWSQLSSDGSNLYWKSHE-----FVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQF--RAPCTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLI--KDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPS----GHRQKPTEKEFSVELKDLEPGEIYKIWVEARTGSSKVA--QSAEIEAQTFSRVSLPEITTRTPRSVTFIWR-SPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWN---SNNDLVESFELQARI-HDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLV----VVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQVQCRDPRRL 1532
+++D NG +FW + ++ + D S+ + I+ A L + +D + RLLV Q+ ++ + L D ++ NL +Q F+++ L N +YWTN ++L + + +F +S+ + + +V QP PVP+NP V+ G + +A+V W WQ W+Y++ ++ S E + Q E ++ V + + + A + G+ WS +L P+G + + W + +SD+ G N + ++ + VA L+ ++ L +++ N+ + + + S+ +Y PK I R + +E + I A VK L +DSL A L W G ++ S L G R ++++ + L +D +++ R S +V+++ + IP+ + ++ L+HS G L Y+ + L W+QD V DL GQ+ + I L G + I D + P+ + +++ + P V++DS+++ + SK V G V Y + H A T E +A + +P + VT+ A + W S K L +P S P + R F + + SI+ RW+ P PNG I GY + +I D I V P LE +V L + + ++ G + ++ I F P +PQIL+ LD DLDR AI+ ++ IN ++E V+ + A IL L VDWI+ +F+ V GS I R + ++G + + T +++ PL LY+ + + ++ L G ++P HA+ CSC PF +RP N + ++ +G+L D GC C ++ + +P S L+ D N+YW + + F+ LN + +I F+ S ++ Q P +CL+P V V ++E + +++ LP+ C LP +T+Y +E P C + + +V +Q ++ LI K+L+PFT+Y + L ++ EL + +T G P PENV AL P + W+PPKV NG + Y++H+ +++ R + ++P + + S L+ L PG+ Y ++V A + S + +S + + + + +T ++ S+ W + I + ++ +V L+ +W + +S++ + + I++L P T Y Q L R +IWP D+ R ET D P PG P + K+ S ++W ++ + + L+ R+ DSN+ E+ S W++ Y T W G + Y FRV+A+N +G+ ++SE + +++ +S + + + G ++GLS + I+GV++ V + ++ +R DKK + ++ELAT+ E+P ++SN Y I ++ + +PK+KR QITL F+G GAFG+V D + L
Sbjct: 422 IEVDPYNGYLFWVRKDGLFRLDLADISNGIKHETHPDLILEDAHLEAFMVDHRNFRLLVPHHVQNTVISVTL---DGREVSNLRANTQQPKFKNVVS--LAMANGLFYWTNGQDILKEDYHPGQDRYFHNSYPDRSCVSVNVLMDAS-QPAPVPVNPPTGVQAVLGAH------MAKVSWRAPYLLGGQGKGAWQNWSYELEIKDVSTGEPIHQEEIGGSSHTVYHLRERSEYLIKAAAYTSAGRGPWSSEFRGCTLRDPKGGSYASILWSASEGLLRSDVTGENVETLIQKSSWKDSDMEYHIIDVAWYKDLLYLVGNNSMLYCYNMTSHETYRLHINS-VRSVAVDWISKKLYWANPKQQIITRANLDGTQQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVSRLNGQDRRYYHSDEIFNGKQVMGLTLDTENKSVYWIVRSYESGSVLYRAPTSE-RIPMNQEIVPEKLSALQHSNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLQMVAIMDHALHQYPKNLSSENITVLPSAVNVDSIRVVGNWSKFNVSWDPVRNTNYGTVFYEVKYADHINTNANPEITKETTIAYNNSERFSPYAILEVTIKAFTYWGMSHHTRKILRSPQAEPSHPTNPRGFVEFNKKPLSDDTDISIVFRWDQPDHPNGLILGYTIVCWYMKDDTKITICDKINVPPKNLEYKVDKVLSNTTYYFKVQAHTIVGAGWFTDVINISTEFEYP-VPQILV------ATLDAVRISDLDRGINDTITRHIAIEVAYSAAENKIY----------WINEMQEMVIADIDSSNATKILALNNSASSLCVDWITRTLFWTESEYRETVVGS--QIMRLDLTAWEAGYTKVEKIITTNRAASKLDISPLMGILYWIESSQNDRGI-IMQSDLHG--DDIQPFFNHAEDCSC-------PFAPLVRPVMAVDNTDIHNPVIYWVSQEGNLNIADIEGCVCNMVLSPDSGKGLPPTS-LTVDKVNVYWSNIDQDQVYFINKLNPDDTEIKKFHLYSARS---LKAIGNSLQPYPFAECLIPRQVSYNVELIEKFANSIKIKLPEPVPHFGCDKFHLPATLYTVYI--------TECLVNDPRDCKN------RERVRVQS-----YEKLIEAKNLKPFTKYMFQVGLSNYYSELESSTLELGPGNIIRTDAGAPTRPENVVVQALTPTLASINWMPPKVLNGAVVRYEIHWRSAQLVNGIRQKGEQLIKNTEQPADGKLSAMLQPLLPGQEYLVYVRAYSAHSTTSYNESVPLSVRMYPEPNNLTLTGQSINSMNVSWAPNESITIVYHLEYSIVGLE--------KWQIATNSVKRNDKVEFIIQNLRPRTLYRFQ--LVLRYPNYNQDFIWPADA-RFTFETSGDVPSAPGIP-ISTKLRGSVHQISWEPAQAHGSQITLYRLEGRVVEDSNLVEENRNDTSQWNLYYNGTDASWISVGEMNQKYQFRVQARNAYGFGKWSEISGVVDLTEAVSGILVARQHLGLVLGLSVPL--ILGVMLLCFGVFLCPVYRQRKEDKKVVIP-PTMPDVELATLREIP--RGNFVQSNALYASAIQNDPDDSALPKIKREQITLAKFLGSGAFGEVFQGDAKDL 1990 HSP 2 Score: 209.534 bits (532), Expect = 2.061e-50 Identity = 95/165 (57.58%), Postives = 122/165 (73.94%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEV 1699
L L DL +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVL+WEI +LG+ PYP NL+V+ V GG P NCP L LMLRCW+ D RP+F+ CL +
Sbjct: 2073 LRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLYHVRAGGRLPKPLNCPTALHQLMLRCWST-ADARPSFKACLDHI 2235
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|817083235|ref|XP_012264217.1| (proto-oncogene tyrosine-protein kinase ROS isoform X1 [Athalia rosae]) HSP 1 Score: 327.02 bits (837), Expect = 2.143e-86 Identity = 395/1654 (23.88%), Postives = 712/1654 (43.05%), Query Frame = 0
Query: 11 LQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNA-NVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAE---ETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSL--PEGPTDLVLTWIRKGQVFQSDLLGTNHSRV---------ELPFKARHVACRSGDAVLLSTDTSL----LSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEED-SKL------VWRALTGEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQM---------EINSLDTIIVHPDTLE-QVLVELPSQQLHIDLRCQNNAGLSPASTLL-IQNRFVLPSLPQILIYQGIQGGKLD---FYDLDRRRIRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVL-----TQAELILHLR-------VDWISNCIFFV------AVSGSDYSIRRFSV---DSGV--LSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRP-----NIPEQKASLTLLTHDGSLFATD-NGCECQLM------RKIPAWSQLSSDGSNLYWKSHE-----FVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQF--RAPCTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLI--KDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPS----GHRQKPTEKEFSVELKDLEPGEIYKIWVEARTGSSKVA--QSAEIEAQTFSRVSLPEITTRTPRSVTFIWR-SPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWN---SNNDLVESFELQARI-HDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLV----VVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQVQCRDPRRL 1532
+++D NG +FW + ++ + D S+ + I+ A L + +D + RLLV Q+ ++ + L D ++ NL +Q F+++ L N +YWTN ++L + + +F +S+ + + +V QP PVP+NP V+ G + +A+V W WQ W+Y++ ++ S E + Q E ++ V + + + A + G+ WS +L P+G + + W + +SD+ G N + ++ + VA L+ ++ L +++ N+ + + + S+ +Y PK I R + +E + I A VK L +DSL A L W G ++ S L G R ++++ + L +D +++ R S +V+++ + IP+ + ++ L+HS G L Y+ + L W+QD V DL GQ+ + I L G + I D + P+ + +++ + P V++DS+++ + SK V G V Y + H A T E +A + +P + VT+ A + W S K L +P S P + R F + + SI+ RW+ P PNG I GY + +I D I V P LE +V L + + ++ G + ++ I F P +PQIL+ LD DLDR AI+ ++ IN ++E V+ + A IL L VDWI+ +F+ V GS I R + ++G + + T +++ PL LY+ + + ++ L G ++P HA+ CSC PF +RP N + ++ +G+L D GC C ++ + +P S L+ D N+YW + + F+ LN + +I F+ S ++ Q P +CL+P V V ++E + +++ LP+ C LP +T+Y +E P C + + +V +Q ++ LI K+L+PFT+Y + L ++ EL + +T G P PENV AL P + W+PPKV NG + Y++H+ +++ R + ++P + + S L+ L PG+ Y ++V A + S + +S + + + + +T ++ S+ W + I + ++ +V L+ +W + +S++ + + I++L P T Y Q L R +IWP D+ R ET D P PG P + K+ S ++W ++ + + L+ R+ DSN+ E+ S W++ Y T W G + Y FRV+A+N +G+ ++SE + +++ +S + + + G ++GLS + I+GV++ V + ++ +R DKK + ++ELAT+ E+P ++SN Y I ++ + +PK+KR QITL F+G GAFG+V D + L
Sbjct: 465 IEVDPYNGYLFWVRKDGLFRLDLADISNGIKHETHPDLILEDAHLEAFMVDHRNFRLLVPHHVQNTVISVTL---DGREVSNLRANTQQPKFKNVVS--LAMANGLFYWTNGQDILKEDYHPGQDRYFHNSYPDRSCVSVNVLMDAS-QPAPVPVNPPTGVQAVLGAH------MAKVSWRAPYLLGGQGKGAWQNWSYELEIKDVSTGEPIHQEEIGGSSHTVYHLRERSEYLIKAAAYTSAGRGPWSSEFRGCTLRDPKGGSYASILWSASEGLLRSDVTGENVETLIQKSSWKDSDMEYHIIDVAWYKDLLYLVGNNSMLYCYNMTSHETYRLHINS-VRSVAVDWISKKLYWANPKQQIITRANLDGTQQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVSRLNGQDRRYYHSDEIFNGKQVMGLTLDTENKSVYWIVRSYESGSVLYRAPTSE-RIPMNQEIVPEKLSALQHSNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLQMVAIMDHALHQYPKNLSSENITVLPSAVNVDSIRVVGNWSKFNVSWDPVRNTNYGTVFYEVKYADHINTNANPEITKETTIAYNNSERFSPYAILEVTIKAFTYWGMSHHTRKILRSPQAEPSHPTNPRGFVEFNKKPLSDDTDISIVFRWDQPDHPNGLILGYTIVCWYMKDDTKITICDKINVPPKNLEYKVDKVLSNTTYYFKVQAHTIVGAGWFTDVINISTEFEYP-VPQILV------ATLDAVRISDLDRGINDTITRHIAIEVAYSAAENKIY----------WINEMQEMVIADIDSSNATKILALNNSASSLCVDWITRTLFWTESEYRETVVGS--QIMRLDLTAWEAGYTKVEKIITTNRAASKLDISPLMGILYWIESSQNDRGI-IMQSDLHG--DDIQPFFNHAEDCSC-------PFAPLVRPVMAVDNTDIHNPVIYWVSQEGNLNIADIEGCVCNMVLSPDSGKGLPPTS-LTVDKVNVYWSNIDQDQVYFINKLNPDDTEIKKFHLYSARS---LKAIGNSLQPYPFAECLIPRQVSYNVELIEKFANSIKIKLPEPVPHFGCDKFHLPATLYTVYI--------TECLVNDPRDCKN------RERVRVQS-----YEKLIEAKNLKPFTKYMFQVGLSNYYSELESSTLELGPGNIIRTDAGAPTRPENVVVQALTPTLASINWMPPKVLNGAVVRYEIHWRSAQLVNGIRQKGEQLIKNTEQPADGKLSAMLQPLLPGQEYLVYVRAYSAHSTTSYNESVPLSVRMYPEPNNLTLTGQSINSMNVSWAPNESITIVYHLEYSIVGLE--------KWQIATNSVKRNDKVEFIIQNLRPRTLYRFQ--LVLRYPNYNQDFIWPADA-RFTFETSGDVPSAPGIP-ISTKLRGSVHQISWEPAQAHGSQITLYRLEGRVVEDSNLVEENRNDTSQWNLYYNGTDASWISVGEMNQKYQFRVQARNAYGFGKWSEISGVVDLTEAVSGILVARQHLGLVLGLSVPL--ILGVMLLCFGVFLCPVYRQRKEDKKVVIP-PTMPDVELATLREIP--RGNFVQSNALYASAIQNDPDDSALPKIKREQITLAKFLGSGAFGEVFQGDAKDL 2033 HSP 2 Score: 209.534 bits (532), Expect = 2.116e-50 Identity = 96/168 (57.14%), Postives = 123/168 (73.21%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
L L DL +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVL+WEI +LG+ PYP NL+V+ V GG P NCP L LMLRCW+ D RP+F+ CL + L
Sbjct: 2116 LRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLYHVRAGGRLPKPLNCPTALHQLMLRCWST-ADARPSFKACLDHIITL 2281
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|817083239|ref|XP_012264219.1| (proto-oncogene tyrosine-protein kinase ROS isoform X3 [Athalia rosae]) HSP 1 Score: 326.25 bits (835), Expect = 3.294e-86 Identity = 395/1654 (23.88%), Postives = 712/1654 (43.05%), Query Frame = 0
Query: 11 LQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNA-NVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAE---ETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSL--PEGPTDLVLTWIRKGQVFQSDLLGTNHSRV---------ELPFKARHVACRSGDAVLLSTDTSL----LSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLEED-SKL------VWRALTGEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGYQM---------EINSLDTIIVHPDTLE-QVLVELPSQQLHIDLRCQNNAGLSPASTLL-IQNRFVLPSLPQILIYQGIQGGKLD---FYDLDRRRIRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVL-----TQAELILHLR-------VDWISNCIFFV------AVSGSDYSIRRFSV---DSGV--LSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRP-----NIPEQKASLTLLTHDGSLFATD-NGCECQLM------RKIPAWSQLSSDGSNLYWKSHE-----FVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQF--RAPCTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLI--KDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPS----GHRQKPTEKEFSVELKDLEPGEIYKIWVEARTGSSKVA--QSAEIEAQTFSRVSLPEITTRTPRSVTFIWR-SPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAWN---SNNDLVESFELQARI-HDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLV----VVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQVQCRDPRRL 1532
+++D NG +FW + ++ + D S+ + I+ A L + +D + RLLV Q+ ++ + L D ++ NL +Q F+++ L N +YWTN ++L + + +F +S+ + + +V QP PVP+NP V+ G + +A+V W WQ W+Y++ ++ S E + Q E ++ V + + + A + G+ WS +L P+G + + W + +SD+ G N + ++ + VA L+ ++ L +++ N+ + + + S+ +Y PK I R + +E + I A VK L +DSL A L W G ++ S L G R ++++ + L +D +++ R S +V+++ + IP+ + ++ L+HS G L Y+ + L W+QD V DL GQ+ + I L G + I D + P+ + +++ + P V++DS+++ + SK V G V Y + H A T E +A + +P + VT+ A + W S K L +P S P + R F + + SI+ RW+ P PNG I GY + +I D I V P LE +V L + + ++ G + ++ I F P +PQIL+ LD DLDR AI+ ++ IN ++E V+ + A IL L VDWI+ +F+ V GS I R + ++G + + T +++ PL LY+ + + ++ L G ++P HA+ CSC PF +RP N + ++ +G+L D GC C ++ + +P S L+ D N+YW + + F+ LN + +I F+ S ++ Q P +CL+P V V ++E + +++ LP+ C LP +T+Y +E P C + + +V +Q ++ LI K+L+PFT+Y + L ++ EL + +T G P PENV AL P + W+PPKV NG + Y++H+ +++ R + ++P + + S L+ L PG+ Y ++V A + S + +S + + + + +T ++ S+ W + I + ++ +V L+ +W + +S++ + + I++L P T Y Q L R +IWP D+ R ET D P PG P + K+ S ++W ++ + + L+ R+ DSN+ E+ S W++ Y T W G + Y FRV+A+N +G+ ++SE + +++ +S + + + G ++GLS + I+GV++ V + ++ +R DKK + ++ELAT+ E+P ++SN Y I ++ + +PK+KR QITL F+G GAFG+V D + L
Sbjct: 465 IEVDPYNGYLFWVRKDGLFRLDLADISNGIKHETHPDLILEDAHLEAFMVDHRNFRLLVPHHVQNTVISVTL---DGREVSNLRANTQQPKFKNVVS--LAMANGLFYWTNGQDILKEDYHPGQDRYFHNSYPDRSCVSVNVLMDAS-QPAPVPVNPPTGVQAVLGAH------MAKVSWRAPYLLGGQGKGAWQNWSYELEIKDVSTGEPIHQEEIGGSSHTVYHLRERSEYLIKAAAYTSAGRGPWSSEFRGCTLRDPKGGSYASILWSASEGLLRSDVTGENVETLIQKSSWKDSDMEYHIIDVAWYKDLLYLVGNNSMLYCYNMTSHETYRLHINS-VRSVAVDWISKKLYWANPKQQIITRANLDGTQQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVSRLNGQDRRYYHSDEIFNGKQVMGLTLDTENKSVYWIVRSYESGSVLYRAPTSE-RIPMNQEIVPEKLSALQHSNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAVINGITLSGLQMVAIMDHALHQYPKNLSSENITVLPSAVNVDSIRVVGNWSKFNVSWDPVRNTNYGTVFYEVKYADHINTNANPEITKETTIAYNNSERFSPYAILEVTIKAFTYWGMSHHTRKILRSPQAEPSHPTNPRGFVEFNKKPLSDDTDISIVFRWDQPDHPNGLILGYTIVCWYMKDDTKITICDKINVPPKNLEYKVDKVLSNTTYYFKVQAHTIVGAGWFTDVINISTEFEYP-VPQILV------ATLDAVRISDLDRGINDTITRHIAIEVAYSAAENKIY----------WINEMQEMVIADIDSSNATKILALNNSASSLCVDWITRTLFWTESEYRETVVGS--QIMRLDLTAWEAGYTKVEKIITTNRAASKLDISPLMGILYWIESSQNDRGI-IMQSDLHG--DDIQPFFNHAEDCSC-------PFAPLVRPVMAVDNTDIHNPVIYWVSQEGNLNIADIEGCVCNMVLSPDSGKGLPPTS-LTVDKVNVYWSNIDQDQVYFINKLNPDDTEIKKFHLYSARS---LKAIGNSLQPYPFAECLIPRQVSYNVELIEKFANSIKIKLPEPVPHFGCDKFHLPATLYTVYI--------TECLVNDPRDCKN------RERVRVQS-----YEKLIEAKNLKPFTKYMFQVGLSNYYSELESSTLELGPGNIIRTDAGAPTRPENVVVQALTPTLASINWMPPKVLNGAVVRYEIHWRSAQLVNGIRQKGEQLIKNTEQPADGKLSAMLQPLLPGQEYLVYVRAYSAHSTTSYNESVPLSVRMYPEPNNLTLTGQSINSMNVSWAPNESITIVYHLEYSIVGLE--------KWQIATNSVKRNDKVEFIIQNLRPRTLYRFQ--LVLRYPNYNQDFIWPADA-RFTFETSGDVPSAPGIP-ISTKLRGSVHQISWEPAQAHGSQITLYRLEGRVVEDSNLVEENRNDTSQWNLYYNGTDASWISVGEMNQKYQFRVQARNAYGFGKWSEISGVVDLTEAVSGILVARQHLGLVLGLSVPL--ILGVMLLCFGVFLCPVYRQRKEDKKVVIP-PTMPDVELATLREIP--RGNFVQSNALYASAIQNDPDDSALPKIKREQITLAKFLGSGAFGEVFQGDAKDL 2033 HSP 2 Score: 209.534 bits (532), Expect = 2.413e-50 Identity = 96/168 (57.14%), Postives = 123/168 (73.21%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
L L DL +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVL+WEI +LG+ PYP NL+V+ V GG P NCP L LMLRCW+ D RP+F+ CL + L
Sbjct: 2116 LRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLYHVRAGGRLPKPLNCPTALHQLMLRCWST-ADARPSFKACLDHIITL 2281
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|1004403082|gb|KYB29372.1| (sevenless [Tribolium castaneum]) HSP 1 Score: 325.865 bits (834), Expect = 3.981e-86 Identity = 392/1628 (24.08%), Postives = 683/1628 (41.95%), Query Frame = 0
Query: 15 SVNGNVFWHT-GNEIWTVSKCDPSSSKR-------IVHRAKLG--SMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGI--LFHYNDSYYWTNANVLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEI-----QPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQAEETNL----VTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTN------HSRV------ELPFKARHVACRSGDAVLLSTDTSLLSAQGQILFKANAEISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFFTRKDGSQTVIHQMDLEDLSIPVQ---VVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTILLGGRGGRITDLCVQGAPRQMVPQ--DLDITPLTVDLDSLKL---EEDSKLVWRALT----GEVTYHLLIQVHGRQ-YALQTTTSELDLAQEIASLTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF----HNAVNSSIIVRWNPPKLPNGHITGYQMEINSLDT---------IIVHPDTLEQVLVELPSQQLH-IDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRR----IRATYDVGAIQTLDFQGPKAVFSQGGSIFALNLINHVRERVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFS-----VDSGV--LSNVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELS----LFGRIKSLKPTSTHAQCSCFQMDPRSPFYFTLRPNIPEQKASLTLLTHD--GSLFATDNGCECQLMRK------IPAWSQLSSDGSNLYWKSHEFVQYLNLQEGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVP-SLVEQRVTILEAGEDWLRVSLPQFRAPCTN-SLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTLIKDLEPFTRYGIYLSLQKGKPSQQTIPTELIALAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQK----------PTEKEFSVELKDLEPGEIYKIWVEARTGSSKV-AQSAEIEAQTFSRVSLPEITTRTPRSVTFIWRSPPIKAIQAFQFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW----NSNNDLVESFELQA-RIHDSNVTVEDNVTM------------SNWSVVYADTSPQWPISGLSDA-AYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKS--ALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
+V G +FW G ++ + D S+ R I+ KL + +D + RL V + + ++ V D +I+N+ R +S E + L N +YWTN + + N S +F +S+ D+ L T + I QPIP P+NP V+ FG+N +A+ W P WQ W+Y++ ++ + ++K N ++ + T + A + G+ WS +L ++ W + ++D G N SR+ ++ + V + D+ + DT S QGQ++ + + + + +Y PK I+R + +E L I K L++DS+ A L W G ++ C+ L G + + L+S + L +D +++ + + + + + S + +T L+ G L Y+H +L W+QD DL G + +TI G +T + V + ++P ++ + P TVD +S+++ + W + G+V Y + I R A+ T ++ + Q++A P T+++V + A + W SPQ+ +++P S P +LRA+ + N +I VRW PP PNG + GY++ L+ ++ P+ Q+ + P ++ +++ + G S + N LP++L+ + D+D R + I L + Q ++ +++ + ++ + + + VDW+ I++ D F VD G+ +S V T I +E+ P T LY+ + K + + S F + K K ++ C+C +D +TL + E K L + D + A NGC C ++ +P +L SD LYW + + L +E + + R+ I F P Q P +CL P L RVT+ E L + +P+ C + S+P VE+ IYY I +C L + +F IK L+PFT Y + +++ ++ I + QT G P PP+NVT L+P +V+W PP+ NG VHYE++ T R SG RQK P ++ L L P E Y IWV+A + +++ + S +++ T+ S + RT +T W I + ++ P+ SN W + + G ++L P TQY + L++ YIWPQDS R + ET D P PG P + + + +Y W N +E ++L+ + + N T W Y T W I+GLS+ Y FRV A N +GWS S+ + ++ +++ + + TLI ++ I + V ++++L I R+ K + I R ++ELAT+ ELP G +N Y P+ +EM +P ++R+QITL+ F+G GAFG+V
Sbjct: 396 AVAGYLFWGIHGTGLYRLDISDFSNGIRHEVQPVLILSEKKLNMSAFTVDHTNFRLFVANEREK---TINTVSLDGKEIINV----RPNVIKSKLENVVSLATANKKFYWTNGDDIFYEEYHN-SVYFHNSYP-DLSLSTKSYKKVIINLQSSQPIPSPVNPPTNVQAIFGSN------IAKTTWLPPHLLGIQGKGAWQNWSYEVAIK-EVGSQKFISHRNINTTSYKISGLRENTEYVIKAAAYTRSGQGPWSSEFRGFTLSRSKNPMIY-WSAAKGLLRTDAAGENVETLIHKSRIKGSVFIDMTWYQDLVYLVTNDSHVYWYDTRSHS-QGQLI--GIDSVGSIAVDWIGKKLYWSNPKRQMIIRGNLNGTQQEPLPILTLA-KELNIDSVKAYLYW-STGFAVRCAHLNGENLIEYHPVQLFSGRQVMGLTLDMHNKFVYWIVRGLEGSNLFRAPMAGYSEKITENFKITSLQKPNMQGPLCYFHKRLLWLQDNKNAAISDLQGNNIATIS-GKSMSDLTLVYVVDSSLHVMPDIPEIVVIPETVDKNSVRVIGSLNSFNVTWNPVKNVNYGQVFYEVSIDSLLRNDSAIVTNSTSVRYWQQVA---PFTKLQVAIRAFTYWGTSPQIRAKVYSPASTPSVPTNLRAYVTHHSSGTNVTITVRWGPPLFPNGVLKGYKIHCWYLNAAQRRDVCRDLVKKPEEF-QIDFKPPHDHIYYFNVQAFSEMGDGDLSDPIQVNSSQELPLPRLLV---ASEDSIFIQDIDSDRNESLLHGIVTPTEIGYLIKESKLFWIDQLQNLMMYDMLKGNKTKITSLRNNVTGVTVDWLERSIYYAQSENWDSGSSVFKLDLNYVDRGIVKMSKVFFTPASISKIEVSPYTRKLYW--VEKSKLMVCNTDGSDKSEFFNKNKYTKRSTLGGGCNC-PVDVNIEKTYTLDHST-ETKPLLVFVESDTQNVVSADKNGCSCSVIANNSLGVTLPL-DRLKSDFGTLYWTNSRLLHALRKKEANLVTKEVNGRD----ILIFGPHMQPFPPSECLRPRQLANIRVTLKEKTATSLTLVMPEVGQICADTSMPTVEYRIYY----------AEKIDNNTCD--------LTCNFSATFDKEFT--IKSLKPFTHYVVAVAVSNYYTEEEEIVLGPSTVFQTAVGAPSPPQNVTVKVLNPTMAQVSWSPPQHPNG----VTVHYEIY--CQTERTLSGVRQKEQSNVEQQFTPNSHFLTIVLNKLSPNETYTIWVKAYSETNETSSDSDKVQINTYPEPSDLILVNRTAYMLTVTWDV--CANIDHYNVQMSPVTSN------DW---RNVSESGEGIFASEENLQPKTQYKFRLSLSYY--NYPEEYIWPQDS-RFVYETLGDKPSPPGTPKI--QYVKPNIYKVWWEEAKDNGAPIELYKLEGLELPNYRTKRSTNRTAFFYTAPSVEEEEREWQQFYNGTETSWIINGLSEKYKYEFRVLALNAYGWSDPSDSSTAFDLN--EAARMAEKQSPMTLIAIATFIP--VSVFLIILLCIVCRKYGKPKKVQVVSIPRGPDVELATLRELP--RRGIHNTNVLYVSTQPTSEEMTLLPHIRRDQITLMKFLGSGAFGEV 1936 HSP 2 Score: 228.409 bits (581), Expect = 3.344e-56 Identity = 103/168 (61.31%), Postives = 129/168 (76.79%), Query Frame = 0
Query: 1535 LTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
L+L +L ++C DVAKGC YL +M ++HRD+A RNCLVSS D DR+VKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVLLWEIM LG+ PYP NNL+V+ +V GG P +CPE L NLML+CW F D+RPTF+ CL + L
Sbjct: 2027 LSLIELLKMCVDVAKGCRYLEEMHFVHRDLACRNCLVSSKDP-DRIVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLLWEIMTLGQ-QPYPARNNLEVLHYVRRGGRLGKPTDCPETLHNLMLKCWEFEADKRPTFKYCLDVLDNL 2192
BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Match: gi|915664849|gb|KOC66937.1| (Proto-oncogene tyrosine-protein kinase ROS [Habropoda laboriosa]) HSP 1 Score: 317.005 bits (811), Expect = 2.693e-83 Identity = 387/1632 (23.71%), Postives = 691/1632 (42.34%), Query Frame = 0
Query: 1 LAEKLGRIVDLQLDSVNGNVFWHTGNEIWTVSKCDPSSSKR-------IVHRAKLGSMGIDFGSNRLLVVDLEQDELLMLDLVDHDHAKILNLTFEERQRPFQSMSEGILFHYNDSYYWTNAN-VLHQLMGDNRSGHFQSSFKEDIDLRTSVFHHPEIQPIPVPLNPVLKVELSFGTNFLGCSSVARVKWEPSD--NSANPCVWQQWTYDIRLESKSATEKVFQ---AEETNLVTCVEHGTVFNASVRAVSEGGKSEWSIPVSAQSLPEGPTDLVLTWIRKGQVFQSDLLGTN------HSRVELPFKARHVACRS--GDAVLLSTDTSLL---SAQGQILFKANAE-ISGLLFEPFSESVYTMVPKSDEILRIPRPNSSEEVLKIPARGVKALDLDSLLAKLCWIRYGTSIVCSSLFGTSPRAILELDLWSESLISDLVIDGLGHRLFF-TRKDGSQTVIHQMDLEDLSIPV------QVVTILEHSTRSGSLNYYHDKLQWIQDGNQLVTFDLVGQSWSTI----LLGGRGGRITDLCVQGAPRQMVPQDLDITPLTVDLDSLKLE---EDSKLVWRALT----GEVTYHLLIQVHGRQYALQTTTSELDLAQEIAS-LTPNTEVRVTLIAASNWSKSPQVEKTLFTPPQISSPPQHLRAF--------HNAVNSSIIVRWNPPKLPNGHITGY---------QMEINSLDTIIVHPDTLEQVLVE--LPSQQLHIDLRCQNNAGLSPASTLLIQNRFVLPSLPQILIYQGIQGGKLDFYDLDRRRIRATYDVGAIQTLDFQGPKAVF--SQGGSIFALNLINHVRERVLTQAELILHLRVDWISNCIFFVAVSGSDYSIRRFSVD-----SGVLS--NVTHTQDDIQHMELDPLTNTLYYTTLTSGKFQLNKLELSLFGRIKSLKPTSTHAQ-CSCFQMDPRSPFYFTLRPNIPEQKASLTLLTHDGSLFATD-NGCECQLM------RKIPAWSQLSSDGSNLYWK--SHEFVQYLNLQ---EGQISHFNGSSRNEGVIIRPFCPDCQMTPIKQCLVPSLVEQRVTILEAGEDWLRVSLPQF--RAPC-TNSLPQVEFTIYYYVIESQGHSELPSITPESCSSHPSLCLKLQVPIQGPEESQFQTL-----IKDLEPFTRYGIYLSLQKGKPSQQTIPTELIA--LAQTLDGQPGPPENVTATALDPETIEVAWLPPKVANGKFIIYDVHYELHKVITTSRIPSGHRQKPTEK----EFSVELKDLEPGEIYKIWVEARTGSSKVAQSAEIEAQTFSRVSLPEITTRTPRSVTFI---WRSPPIKAIQAF--QFRLVPLKSNLNASQYQWPMELSSIQPGHQYQGQIKSLNPGTQYGLQGVLTFRIGQRTHTYIWPQDSKRILVETPPDAPLIPGQPYVMEKVSESQVYLAW---NSNNDLVESFELQA-RIHDSNVTVEDNVTMSNWSVVYADTSPQWPISGLSDAAYLFRVRAKNEFGWSQFSEDTPPLNIGLILSSKGLFQSNSGTLIGLSAGIVGIIGVLVVVVLIIFLRRPWDKKSALGIQRHRELELATIHELPVMLNGGMESNPTYGVQIPSEQEMEDIPKLKRNQITLVNFIGCGAFGQV 1524
+A L R +++D NG +FW T ++ + D S+ + I+ A LG+ +D + RLLV Q+ ++ + L D ++L+L +Q F+++ L N +YWTN VL + ++ +F +++ D F + PV + LG A+V W+ WQ W+Y++ ++ +S E + Q A ++ V + + ++ A + G+ WS ++L +G +L W + +SD+ G N + ++ P H+ S D + + + S L + K N + + + S+ +Y PK I R S +E + I A VK L +DSL A L W G ++ + L G R ++++ + L +D +++ R S +++++ + IP+ + V+ L+H G L Y+ + L W+QD V DL GQ+ + I L G I D + P+ + + + + P V+ S+++E + + W + G V Y + + + T+E + + + P + + VT+ A + W + K L +P I S P + RAF V+ I RW+ P+ NG ITGY + I D + P TL + V+ LP+ + + G P + L+ + +PQ+L+ + DLD+ A++ ++ ++ + +L ++LT L + +DW++ +++ S + R +D G+L N+ + I ++++ P T +LY+ LT + ++ L GR +++P H CSC P N QK + ++ +G L D +GC C L+ + +P + L+ D N+YW + + + ++N + +G+I HF S I+ Q PI CL+P V V ++ + + V LPQ + C T SLP +TIY + + P++C + + ++FQT IKDL+PFT+Y + L+L +++ E + + +T G P PENVT AL P V W+PPK+ N + Y+VH+ L ++I +R K TE+ F L+ P + Y ++V A S E Q P T T SV + W P I + +++ V +++ W + S + IK L P T Y + L R ++WP D R +T D P PG P V K+ S L W ++ + + ++ +I++ N + D+ ++W + Y T W I+G D Y FRV+A+N +G+ +S +P +++ Q + G ++GLS ++ I+ + L ++ +R DKK+ L ++ELAT+ E+P ++SN Y + ++ + +PK++R QITL F+G GAFG+V
Sbjct: 341 VAGFLTRPTHIEVDPYNGYLFWVTRGGLYRLDLADISNGVKHEVQPYLILEDAHLGAFTVDHTNFRLLVPHHIQNTVISVSL---DGREVLDLRSNTQQPKFKNVVS--LAMANGLFYWTNGEEVLIEGYHSGQNRYFHNAYP---DRSNGSFVSVNVLMDASQPVPVPVNPPTGVQAVLGVER-AKVSWQAPHLLGGQGKGAWQNWSYELEIKDESTGETIHQKDIAGSSHTVHNLREKSEYSIKAAAYTSAGRGPWSTEFRGRTLRDGSHASIL-WSANEGLLRSDVTGENIDTLIYKASLKEPETDYHIVDVSWYKDILYIVGNNSALYRYNITNHQKMKMNIHSVGSVAVDWISKKLYWANPKQQIITRANLNGSQQEPMSILAI-VKELMIDSLEAYLYW-STGHAVEVARLNGQDRRYYHSDEIFNGKQVMGLTLDTENRYVYWIVRSYESGSIVYRAPTSE-KIPMTHKIMPEKVSALQHPNMQGPLCYFSEHLLWLQDDRNAVIGDLSGQNTAIINGITLSGLHMVAIMDPALHQYPKNLSSETVVVLPNAVNYSSIRVEGTWRNFNISWDPVENINYGTVFYEVKFADYINTNSNPEITTETSMPYNNSEQILPYSVLEVTVKAFTYWETAHHTRKILRSPQSIPSQPTNSRAFIEFHKEPLSENVDIFAIFRWDQPEFTNGLITGYTVMCWFKEDHVPIQFCDHKSLIPSTLLEHTVQDLLPNTTYYFQVSAHTEIGAGPYTDLINVSTIYENPVPQLLV---ATMDAVRISDLDQEVNYTITRHIAVEVTYMAAENKIYWINEMQELVTSDLNGANATKMLTLNNSALSITIDWVARHLYWSESSYRENGGRVMKLDLTMWHDGILKYENIIASSRRIVNLDILPSTGSLYWIELTKKDGGI-IMQSDLNGR--AIQPFFNHIDDCSCPYRPSVIPVMTIDSTNY--QKPVMYWISMEGHLNIADIDGCACSLIVSAGFNKGLPP-TSLTVDKMNIYWSNIAEDQIYFVNKKYPDDGEIKHFYLPSVRS---IKALGKSLQTYPITNCLIPHQVSYNVEEVKKTANSITVRLPQPVPQFGCETYSLPTTLYTIY---------------VSQCLENDPNMC-------EDSDRTKFQTYEEEYEIKDLKPFTKYRLKLALSNYYADLESMSLEFGSGVVLRTEAGAPTAPENVTVEALTPTLAVVYWMPPKILNAAAVRYEVHWRLVRLINGARQKGEQFIKGTERTTDGRFFTMLEPWLPDQEYLVFVRAYPAHVNDVYS-ESPGQVVKMYPEPNNLTLTGVSVNGLNVTW-VPTINLTIRYTLEYKDVAVEN--------WQVANDSKMVNEKLTYFIKKLQPRTLYKFR--LILRYPNYKLDFVWPTDG-RFTFQTLGDVPSAPGMPTVT-KLRNSVYQLNWEPAQAHGSQITLYRVEGMKINEINEQI-DSSENASWKLFYNGTDNYWIITGDMDDKYRFRVKARNAYGFGGWSRSSPIIDLTETTGGILAAQQHLGLVLGLSVPVITIMLICFCYFLCLYRQRKEDKKAVLP-PLVSDVELATLREIP--RGNFVQSNALYASTLQNDPDDSTLPKIRREQITLAKFLGSGAFGEV 1907 HSP 2 Score: 211.075 bits (536), Expect = 7.799e-51 Identity = 97/171 (56.73%), Postives = 124/171 (72.51%), Query Frame = 0
Query: 1532 LLKLTLADLGQICCDVAKGCAYLSDMQYIHRDIAARNCLVSSLDAKDRVVKIGDFGLARDIYKDAYYRKNGQSLLPIKWMAPESLADNKYTTKSDVWSFGVLLWEIMNLGRCPPYPDMNNLDVMVFVPNGGHPKVPPNCPERLKNLMLRCWAFHPDQRPTFRDCLHEVQEL 1702
L L L DL +C DVA+GC YL ++ ++HRD+A RNCLVS+ D ++RVVKIGDFGLARDIYK+ YYRK G+ LLP++WMAPESL D +T++SDVW+FGVL+WEI +LG+ PYP NL+V+ V GG P NCP L LMLRCW+ D RP+F+ CL + L
Sbjct: 1995 LHALRLQDLLAMCEDVARGCRYLEELHFVHRDLACRNCLVSARDRENRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQ-QPYPARTNLEVLHHVRAGGRLPKPMNCPPGLHQLMLRCWS-AADARPSFKACLEHIVSL 2163 The following BLAST results are available for this feature:
BLAST of proto-oncogene tyrosine-protein kinase ros vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 25
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BLAST of proto-oncogene tyrosine-protein kinase ros vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of proto-oncogene tyrosine-protein kinase ros vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold233_size243130:137587..149272- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold233_size243130-snap-gene-1.22 ID=maker-scaffold233_size243130-snap-gene-1.22|Name=proto-oncogene tyrosine-protein kinase ros|organism=Tigriopus kingsejongensis|type=gene|length=11686bp|location=Sequence derived from alignment at scaffold233_size243130:137587..149272- (Tigriopus kingsejongensis)back to top Synonyms
The feature 'proto-oncogene tyrosine-protein kinase ros' has the following synonyms
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