multidrug resistance-associated protein 1 isoform x4, maker-scaffold2698_size13172-snap-gene-0.3 (gene) Tigriopus kingsejongensis
|
Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000008248 (supercontig:LSalAtl2s:LSalAtl2s498:229862:245360:1 gene:EMLSAG00000008248 transcript:EMLSAT00000008248 description:"maker-LSalAtl2s498-snap-gene-2.25") HSP 1 Score: 1035.79 bits (2677), Expect = 0.000e+0 Identity = 536/1030 (52.04%), Postives = 727/1030 (70.58%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWGKSEP-TVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKK-GILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQK-GDFADFLLEYMSEETED----EQTLMEIKMELEDVLG-EEKVKQEFERQQS---RARTESICSVQSAFSNASS-SNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVW-TEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNK-PEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+GLA+M++ IP N V+ +K+ QM+NKD R+KLM +IL G+KVLKLY WE SF+ + + R +EI LKK+A + A+ +F+W S PFLVAL+SFT YV +D N+L AFV+LT N++R+P+++LP MI+ +Q VSLDRIN ++N E+LD A+ H E Q VK+ N SW E L DI L+I KGSL A+VG VGSGKSSL+S LGEME +GS+NV GQ Y PQQ W+QN T++NNILFGK K Y+ +I+ACAL DL++LP GD TEIGE+GINLSGGQK RVSLAR ++ D+Y+LDDPLSAVD HVG+H+FE VIS + G+L+ KTR+ VTHG +LP+TD IIV+K G ISE G+Y+ L+ ++ G+FA FL+ Y+ +E E+ +Q L I +LE +G E++++ E QS A T+ I + N S ++I S+ D++DE + + + LIE+E E+G + L++Y Y K G G YQ S+G N WL+ W T+ NS+ RN YL +Y LGF Q+ TML S+ +AI TLNAS ++H +L V+R+P+SFFDT PLGRI+NRF+KDIDV TLP N+R + + LGTI++I +P F +I+P I + IQ Y++ +RQ+KR+ESISRSPIYSHF E++TG TIRAFG+ FI+E+ K+D N CY+P++I++RWLAVRLET+GNI+ A+F+I + D G VGL +SYAL+VT +LN L+ +++DVETN+V+VER+KEY + QEA ++LPN P +WP+ G ++F Y RYR GLDLV+K I+C IQ G+ +GIVGRTGAGKSSLT+ALFR++EP+EG+I IDG ++ LGL LR ++TIIPQDP+LFSG+LR+NLDPF +D+++W ALE +HLK+FV +L DGL+ V EGG NLSVGQRQLICLARA+LRKT++L+LDEATAA+DLETDDLIQ+TIR +F+ T
Sbjct: 445 AGLAVMILLIPINIVVGKKVKKFTAIQMQNKDKRIKLMDDILNGIKVLKLYAWEPSFIDAVTNFRVQEIGALKKSALINAVTSFMWTSAPFLVALASFTTYVLIDEKNILTPSTAFVSLTLFNLLRLPLNLLPMMIMKAIQSKVSLDRINLFLNKEDLDLLAISH-ESQGSHAVKMCNVSLSWETDEGLNTLEDIDLDIEKGSLVAIVGQVGSGKSSLLSGILGEMEIVRGSINVDGQTIYAPQQPWLQNETLRNNILFGKRFNKKLYRRVIDACALSPDLDMLPAGDLTEIGERGINLSGGQKARVSLARCTXNNGDIYILDDPLSAVDVHVGRHLFENVISSQTGLLKNKTRIFVTHGAIFLPQTDKIIVMKNGVISESGTYRDLIEKENGEFAQFLINYLVDEKENILKNDQDLKTIIKDLESTVGGSEELEKRLEAAQSDKSTALTDLIQGTKYLDENTSDQCSSIASRKGEDDLDEVV---SNDLNERLIEEEKIESGGIKLNIYLNYFKRTGLLASFFGILFYFSYQGFSLGANLWLSKWSTDRAAINST--SIRNHYLEIYAILGFFQSIFTMLGSVTIAIGTLNASMKIHGKLLENVLRAPLSFFDTNPLGRILNRFSKDIDVAXTTLPFNIRMMIAQSFNVLGTIVIICIALPWFFVIILPAVICYALIQKFYISCARQVKRIESISRSPIYSHFAETLTGIPTIRAFGMVHHFIDENVNKIDFNAKCYFPTVISSRWLAVRLETLGNILVIFVALFSITSRGTTDPGMVGLSLSYALSVTTILNMLITVSTDVETNMVSVERIKEYE-NIPQEAPYDLPNSDPPPNWPEHGVIKFDNYKTRYRKGLDLVLKGINCTIQKGEKIGIVGRTGAGKSSLTLALFRIIEPSEGSIYIDGENIRFLGLGKLRSRITIIPQDPILFSGSLRMNLDPFEAFADRDIWIALEYSHLKSFVWNLGDGLNFSVLEGGRNLSVGQRQLICLARAILRKTQILVLDEATAAIDLETDDLIQSTIRSEFKDST 1467
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000002221 (supercontig:LSalAtl2s:LSalAtl2s1420:21426:31801:1 gene:EMLSAG00000002221 transcript:EMLSAT00000002221 description:"maker-LSalAtl2s1420-augustus-gene-0.12") HSP 1 Score: 1028.08 bits (2657), Expect = 0.000e+0 Identity = 526/1052 (50.00%), Postives = 726/1052 (69.01%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDT--PVKITNGIFSWGKSE-PTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKK-GILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEF--ERQQSRARTESICS---VQSAFSN-----ASSSNAIISQDNVDEV--DEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFG----------------NSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAII---FFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPN-KPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+ +M++ IPFN I S T+ Q QMK KD+R+KL++E++ G+K++KLY WEQSF+ I ++R KE+ +L +L A +F+W PFLV+L +F ++ NVLD++KAFV LT NI+R P+S+LP +I +V GVS+ RINK+MN+EE+D+ A+E D + + W E +L D++L+I GSL AVVGTVGSGKSSL+SA LGEM+K G + V G +AY QQAW+ N ++KNNILF K+ +Y I+EACAL SDL++LPGGD TEIGEKGINLSGGQKQRVSLARA YS +D+YLLDDPLSAVDSHVGKHI++ VIS GIL+ KTRV+VTHG+TYLP TD IIV+K+GR+SE G+Y++L+ QKG FA+F+++++SE E + IK ++E+ G+ ++ ++ +Q R R+ S+ S V S N AS S + +++ DE ++ + T T + E ETGSV ++Y +Y+KN+ VVA + +IYQ + +N L W++ V N + YL +YGG Q ++ + + ++ + A++++H ML +++SPMSFFDTTP GRI+NR KD+DV D+ +P LR W++ F L ++I+++ P+F I+P ++I +FFIQ IYV TSRQLKRLES SRSPI S F E+++GA+TIRA+G FI+ESE KVD NQ +P+ ++NRWLAVRLE +GN+I F AA+ A+L + G VGL +SYAL VT LNWLVRM S+VETNIVAVER++EYT E+EA W + + KP+EDWP+ GE+ F+ Y RYR GLD V+K++ I+GG+ +GIVGRTGAGKSS T+++FR++EP G I IDG+D+++LGLH LR ++TIIPQDPVLFSG+LR NLDP +++ + A+ +HLK F+ SL+DGL + VSEGGENLS+GQRQLICLARALLR+T+VLILDEATAAVDLETD+LIQ TIR +F+ T
Sbjct: 461 AGVLVMILLIPFNGFIASRTKTLQTNQMKEKDERIKLLNEVVQGIKIVKLYAWEQSFLDIISNVRSKEVKILTHIGYLQAGNSFIWTCAPFLVSLVTFATFILSSPENVLDSEKAFVCLTLFNILRFPLSMLPMIIGSMVLAGVSIKRINKFMNSEEIDEEAVEKKTAYPDDKFAINLEKACLKWESDEDKNILSDVSLDIEVGSLVAVVGTVGSGKSSLLSAILGEMDKVSGLITVRGSIAYGAQQAWVLNTSLKNNILFNKSYDGDKYTRIVEACALKSDLDMLPGGDETEIGEKGINLSGGQKQRVSLARAVYSGSDIYLLDDPLSAVDSHVGKHIYDNVISSSSGILKDKTRVMVTHGVTYLPFTDKIIVMKDGRVSEIGTYKELLRQKGAFAEFIVQFLSEANE-NEVNENIKHDIEESFGKNELLEQITKAKQIVRERSVSLNSGDLVTSLVKNNPTNSASGSTTSLKENSGDESTDNDTKQTRPTTSQTQQYQDEKVETGSVKWNIYMHYVKNMSIILVVACSSCFVIYQALNTLSNVLLAWWSDAVMKIEVRTGLNDNRTLDEINQDIMDXQVYYLSIYGGYCLGQGIVVVMGFVFMYLACMEAAQRLHNQMLESILKSPMSFFDTTPQGRILNRLGKDLDVLDSVMPMVLRGWISCFLGVLSSLIVVMVTTPVF---IIPASLIIICYFFIQRIYVATSRQLKRLESSSRSPIXSFFSETVSGAATIRAYGQSSTFISESESKVDDNQKANFPATVSNRWLAVRLEVVGNLIVFTAALLAVLGRDSLSPGLVGLSVSYALAVTASLNWLVRMASEVETNIVAVERIQEYT-KAEKEAPWIIEDTKPDEDWPRKGEISFKNYSTRYREGLDYVLKNVSLDIEGGEKIGIVGRTGAGKSSFTLSMFRIIEPVTGNIIIDGVDITKLGLHQLRSRITIIPQDPVLFSGSLRRNLDPLDEYNETNIMEAISHSHLKPFIDSLKDGLEYHVSEGGENLSLGQRQLICLARALLRRTRVLILDEATAAVDLETDNLIQKTIRSEFKDST 1507 HSP 2 Score: 74.7146 bits (182), Expect = 1.104e-13 Identity = 91/414 (21.98%), Postives = 169/414 (40.82%), Query Frame = 0
Query: 1 MPSGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQ----ILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNV-LDAQKAFVTLTYLN-IMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVK----ITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVG-------------QVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQK 391
+P+ L I++ + V+ +R+ + + ++ SE + G ++ YG +F+ + + D + WL + V + F AL + + G V L A LN ++RM V + V+++RI +Y E+ +E + +D P K N + + VL +++L+I G +VG G+GKSS + +E G++ + G ++ +PQ + + +++ N+ + E I L ++ L G + E G NLS GQ+Q + LARA V +LD+ +AVD I + + S+ + T + + H + + I+VLK G E G+ +L+ K
Sbjct: 1144 IPASL-IIICYFFIQRIYVATSRQLKRLESSSRSPIXSFFSETVSGAATIRAYGQSSTFISESESKVDDNQKANFPATVSNRWLAVRLEVVGNLIVFTAALLAVLGRDSLSPGLVGLSVSYALAVTASLNWLVRMASEVETNI--------VAVERIQEYTKAEKEAPWIIEDTKPDEDWPRKGEISFKNYSTRYREGLDYVLKNVSLDIEGGEKIGIVGRTGAGKSSFTLSMFRIIEPVTGNIIIDGVDITKLGLHQLRSRITIIPQDPVLFSGSLRRNLDPLDEYNETNIMEAISHSHLKPFIDSLKDGLEYHVSEGGENLSLGQRQLICLARALLRRTRVLILDEATAAVDLETDNLIQKTIRSE---FKDSTVITIAHRLNTIMDYSKILVLKNGERVEYGTVAELLADK 1545
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000003611 (supercontig:LSalAtl2s:LSalAtl2s197:49356:53594:-1 gene:EMLSAG00000003611 transcript:EMLSAT00000003611 description:"augustus_masked-LSalAtl2s197-processed-gene-0.4") HSP 1 Score: 1018.45 bits (2632), Expect = 0.000e+0 Identity = 516/1023 (50.44%), Postives = 694/1023 (67.84%), Query Frame = 0
Query: 4 GLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALE------HDEKQKDTPVKITNGIFSWGKSEP-TVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKK-GILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
G I++I IP NA++ F +K+Q++QMK KD+R K+++E+LGG+++LKLY WE S++ +I IR EI +LKK AWL + + F+W S PF+VAL+SF +V +D N+L A+KAFVT +Y+N M+MPM+ PF+I+ + VSL RIN+ + ++EL +A+E + + + + I +G F W + L +I L I GSLTA+VGTVGSGKSSLISA LGEM K+ G V + GQ+AYVPQ++WMQN ++KNNILFGK ++ Y +++E C L DL +LP GD TEIGE+GINLSGGQ+QR+SLARA YSDADVY+ D+PLSA+DS VGK +F V++ GI++ KTR+LVTHGI+YLP HI V+ +G +++H+ G + + L E++ + E + + +N D LE +A +I+KE ETG V SVY YY+++IG+ G Q++ Q+ G++ WL WT+ +GN++ P+YR+LYLGVYG LG QA + LLS+ +A+ TL ASK +H R+MR+P+SFFD+TP GRI+NRF+KDI +CDN L +N+RQWL FLG +ILI++V+P+F +P +++F IQ+IYV +SRQLKRL+S++RSPIYSHF ES+ G S+IRA+G + +FI ES K+D NQ C YPSIIANRWLA+RLETIGN+ F AI + NP + G+VGL+ISYAL +TQ LNWL R TS++ETNIVAVER+KEY L+ E EW L +WP G+VEF+ Y +RY+ DLV+K I+ I GG+ VGIVGRTGAGKSSL+VALFR+VE A G I IDG D+S LGLHDLR+ LT+IPQ+P+LFSGTLR NLDP SD ++W L HLK ++ L+DGL+H +SEGG NLS GQRQL+CLARALLR K+LILDEATAAVD ETD+ IQ TIR F CT
Sbjct: 375 GTGILLITIPVNAILSYFGKKFQMKQMKAKDNRTKILNEVLGGIRILKLYAWEPSYINKIEGIRGVEIGILKKAAWLTSFMGFIWSSTPFIVALASFATFVMVDDRNILTAEKAFVTQSYINKMKMPMAXFPFVIVXAISATVSLKRINQLLTSDELQKDAVERVPMKINQKIDQGDAIVIRDGNFKWSTEDSENTLSNINLRIKHGSLTAIVGTVGSGKSSLISAILGEMVKKSGKVRIKGQIAYVPQESWMQNTSLKNNILFGKPYDEEWYNQVLEYCCLTYDLSLLPAGDETEIGERGINLSGGQRQRISLARAIYSDADVYIFDNPLSALDSQVGKSVFNNVLNNNTGIIKDKTRLLVTHGISYLPHVHHIAVMLKG---------EIIHE-GTYQELL----------------------------------EKKIIQTIEEEEEQEKDGVQENNINNYNNIPKTFDATVNNLEKAA------IIQKEGLETGRVSWSVYKYYIQSIGFLGAFLIIFNQMLNQLFGFGSSIWLEAWTQEDYGNATIPKYRDLYLGVYGALGIGQAVTIFLLSLSVAMFTLKASKVIHNQTYDRIMRAPISFFDSTPQGRILNRFSKDISICDNILGSNIRQWLXCLFXFLGIVILIVSVLPLFLLFALPTSLVFILIQNIYVASSRQLKRLQSVTRSPIYSHFSESLNGLSSIRAYGAQSKFILESINKIDTNQRCNYPSIIANRWLAMRLETIGNLCIFGXAILTMTNPELVGPGKVGLVISYALILTQNLNWLXRQTSEIETNIVAVERLKEYA-GLDIEKEWRLHKDTSYNWPSQGKVEFKNYSLRYKANSDLVLKKINFTIFGGERVGIVGRTGAGKSSLSVALFRIVEAANGQILIDGKDISTLGLHDLRESLTVIPQEPLLFSGTLRSNLDPENAFSDHDIWNTLGSVHLKEYIRDLKDGLNHSISEGGLNLSSGQRQLMCLARALLRSCKILILDEATAAVDWETDEKIQETIRCYFPSCT 1346 HSP 2 Score: 75.0998 bits (183), Expect = 7.791e-14 Identity = 64/259 (24.71%), Postives = 113/259 (43.63%), Query Frame = 0
Query: 146 VSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQ-------------VAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQL 387
V+++R+ +Y +++ H + + P V+ N + + VL I I G +VG G+GKSSL A +E G + + G+ + +PQ+ + + T+++N+ A D + + L + L G I E G+NLS GQ+Q + LARA + +LD+ +AVD + I E + + T + + H + + D I+VL +G + E GS +L
Sbjct: 1126 VAVERLKEYAG-LDIEKEWRLHKDTSYNWPSQGKVEFKNYSLRYKANSDLVLKKINFTIFGGERVGIVGRTGAGKSSLSVALFRIVEAANGQILIDGKDISTLGLHDLRESLTVIPQEPLLFSGTLRSNLDPENAFSDHDIWNTLGSVHLKEYIRDLKDGLNHSISEGGLNLSSGQRQLMCLARALLRSCKILILDEATAAVDWETDEKIQETI---RCYFPSCTILTIAHRLKTIIDYDKILVLDKGTVIEFGSPNEL 1380
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000011700 (supercontig:LSalAtl2s:LSalAtl2s812:79332:86643:-1 gene:EMLSAG00000011700 transcript:EMLSAT00000011700 description:"maker-LSalAtl2s812-augustus-gene-0.6") HSP 1 Score: 859.751 bits (2220), Expect = 0.000e+0 Identity = 448/1023 (43.79%), Postives = 657/1023 (64.22%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGN-VLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKI-TNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEM---EKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPN--KPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+ +M + IP N I + Q++QMK KD+RVK M+EIL G+K++KLY WE SF I IR +EI +LK ++ + S F ++L +F VYV D N +LD++K FV+++ NI+R P+++L +I G+ VSL RINK++ +EEL++ L + I + FSW S ++ DI++++ +G+L A++G VGSGKSSLISA LGEM K V + G VAY PQ AWMQN +VK+NILFG+ Y E+++AC+L SD+E P GD+TEIGEKGINLSGGQKQR+SLARA YS +D+Y LDDPL+ VDSHV KH+FE+VI G+L GKTR+LVTH +++L D I LK+G I+E+G+Y++ LME + +++ + +N S S ++ + N + +P+E + + ++E TG VG+ VY Y++ IG + F+ +I QI + G++ WL+VW++ N+++ Y +LG+Y GLG F + +++L++S L+AS+ +H T+ ++++PMSFFDTTPLGRI+NRF +DI+V D + + + +++ T+ +I +PIF + + +++F I + +++SRQLKRL S++ SPIYSHFGE+++G +T+RA+ LEK F +E E+++D Q +P I+A+RWL +R+ IGN I FA+A+F++L+ I G++GL +S +L +T +L+W++RM SD+E NIVAVER+KEY+ E EA WEL K WP GE+ + ++YR LD V++DI+ HI G +GIVGRTG+GKS+L +ALFRL+E G I IDG+D+ ++GLH LR KLTIIPQDP LFSGTLR+NLDPFG+ D E+ +L+ A+L+ F+ EDGL ++E GEN+S+GQRQLICLARALLRK KVLI+DEATAAVD ETD LIQ I+ F+ T
Sbjct: 972 AGVLVMFLLIPINGFIAVRMKNAQMKQMKKKDERVKKMNEILQGIKIIKLYAWESSFSKLISSIRFEEIKLLKLSSKYFGFMMLTISSTTFFISLFTFIVYVVSDPENHILDSEKIFVSISLFNILRFPLNMLTHVIGGIASASVSLKRINKFLASEELEEGILVRSNSHDHQAICIHPSSSFSWKGSSESLFKDISMDVNRGNLIAIIGPVGSGKSSLISALLGEMLFTSKGTNPVEIHGSVAYTPQNAWMQNVSVKDNILFGRKFNKNWYDEVLKACSLESDMEXFPSGDSTEIGEKGINLSGGQKQRISLARAVYSQSDIYFLDDPLAXVDSHVAKHLFEEVIGSNGLLRGKTRILVTHNLSFLHLVDEIYFLKDGEITEKGTYKE-------------------------LMEKNCDFSELISNH--------------------ANNKITNQSDSEKVMEKINEEGTKQPIETNF-----KIYDEETLHTGQVGIRVYWYFLSKIGMLAGILAFSFFIISQILATGSSVWLSVWSDA--KNNTDIYY---HLGIYAGLGVSNIFISTAGTLILSLSLLDASRILHGTLFQCIIKTPMSFFDTTPLGRILNRFGQDIEVLDTKMSFCIFGSMTGTFAYIATVTIISINVPIFIIPTLAIFVVYFVILIVSLSSSRQLKRLSSVATSPIYSHFGETLSGINTVRAYSLEKAFYSEFERRLDEYQKRNFPVIMADRWLGIRINLIGNFIIFASALFSVLSRDTITPGQLGLNVSSSLAITSILSWVIRMYSDLENNIVAVERIKEYS-NKESEAPWELEEDLKLNSSWPLKGEITIKNLSLKYRKDLDWVLRDINVHISPGDKIGIVGRTGSGKSTLALALFRLLEVNSGQITIDGVDIKKMGLHTLRSKLTIIPQDPTLFSGTLRLNLDPFGLFKDMELIESLKHAYLQDFLK--EDGLDKVIAENGENISLGQRQLICLARALLRKNKVLIMDEATAAVDSETDKLIQKAIKDNFRDST 1936 HSP 2 Score: 88.5817 bits (218), Expect = 7.284e-18 Identity = 114/410 (27.80%), Postives = 178/410 (43.41%), Query Frame = 0
Query: 5 LAIMVIAIPFNAVIVSFTRKYQLEQMKN--KDDRVKLMSEILGGVKVLKLYGWEQSFMGQI---LD-IRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDT-PVK----ITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVG-------------QVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEAC--ALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLV 388
LAI V+ F +IVS + QL+++ + E L G+ ++ Y E++F + LD + + V+ WLG IN + + F AL F+V + + Q + L I + +S + M L V+++RI +Y N E LE D K + P+K I N + K VL DI + I G +VG GSGKS+L A +E G + + G ++ +PQ + + T++ N+ KD E+IE+ A + D G D I E G N+S GQ+Q + LARA V ++D+ +AVDS K I +K I K T + + H + + IIV+ G I E S + L+
Sbjct: 1577 LAIFVVY--FVILIVSLSSSRQLKRLSSVATSPIYSHFGETLSGINTVRAYSLEKAFYSEFERRLDEYQKRNFPVIMADRWLGIRINLIGNFIIFASAL--FSV---LSRDTITPGQLGLNVSSSLAITSI-LSWVIRMYSDLENNIVAVERIKEYSNKESEAPWELEEDLKLNSSWPLKGEITIKNLSLKYRKDLDWVLRDINVHISPGDKIGIVGRTGSGKSTLALALFRLLEVNSGQITIDGVDIKKMGLHTLRSKLTIIPQDPTLFSGTLRLNLDPFGLFKD---MELIESLKHAYLQDFLKEDGLDKV-IAENGENISLGQRQLICLARALLRKNKVLIMDEATAAVDSETDKLI-QKAI--KDNFRDSTVLTIAHRLQTVLDYSKIIVIDSGCIIEYDSPKNLL 1971
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000000752 (supercontig:LSalAtl2s:LSalAtl2s111:55855:93761:1 gene:EMLSAG00000000752 transcript:EMLSAT00000000752 description:"maker-LSalAtl2s111-augustus-gene-1.10") HSP 1 Score: 542.732 bits (1397), Expect = 1.292e-171 Identity = 356/1049 (33.94%), Postives = 537/1049 (51.19%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMS-VLPFMIIGLVQVGVSLDRINKYMNNEELDD-----NALEHDEKQKDTPVKITNGIFSW-GKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLK-EGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVY-GYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLG---------------FC---------QAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G A+++ I F + K +L D R+++M+EIL G+KV+K+Y WE F+ + + R++ FV + V L+ L G ++AQK F+ + +++P++ P I + VS+ RI +++ EL D N + + + V++T W S L +I+ + G L A++G VG GKS++I + LGE G +N+ G+++Y Q+AW+ + +V+ NIL GK DKRY+E+I CAL D+ P GD T +GEKGI+LSGGQK R++LAR Y+ AD+Y+LDDPLSAVD HVG+ +F+ I K L KT +LVTH + +L ++II+L +G I G+Y++L+ Q G + Y+ +E+E + + L DVL + K E+ R Q + + + S +S+ S I D E K+G+ KE GSV LS+Y Y++ G+F + + + LI V +++WL +WT P Y Y + +C FS L L +S + +S+ +H M +V + FFD P GRI+NRF+KDI D LP L S G ILI P+ IV + +I I+ Y+N SR +KRLE I+RSP++S S+ G +TIR+ +E+ I E + DI+ YY ++ NR+ A + + ++ T + + G+VGL ++ +L + ++ W +R +++VE + +VERV EY L +E + K + WP G +EF ++Y V+K L EP EG I IDG+++ +L L D+RKK++IIPQDP+LF GT+R NLDPF + + +W ALE A L V+ LE GL +VSEGG N SVGQRQL CLARA+LRK KVLI+DEATA VD TD LIQ IR +F+ CT
Sbjct: 563 AGGALLIFFIFFQTYMGKMFSKLRLMTASKTDIRIQIMNEILDGIKVIKMYAWETPFVQLVTNARNR----------------FVLLPVFLLMVLF----------GVEINAQKIFLIFGLFDAIKLPLTHFFPSAISASSEALVSMKRIEEFLLLNELRDVQSKINHVILPGRYEPLTVEVTKISGKWLDSSNEFTLKNISFSVEIGELCAIIGPVGCGKSTIIQSLLGEFPVSYGEINIKGRISYASQEAWIFSGSVRQNILMGKPLIDKRYREVIRVCALEHDVREWPDGDYTFVGEKGISLSGGQKSRINLARCVYASADIYILDDPLSAVDPHVGQQLFDTCIQK--FLSDKTVILVTHQLQFLKNANNIILLNSDGEIEASGTYEKLMSQSG-----FVTYLEATSEEEDSDL-----LSDVLSDVKSDGEYMRSQKKKLKKGVRSRRSSTSLLVPVPYIGGSTERDTFPEEKGSQEWKMGS----KETIIEGSVSLSLYHKYFVAGGGFFKFLCVYFLSLITHTLFVVSDWWLRLWTNAADARKLGPLPPTFYFSEYQDMTLQITADFQVDFFNFIYCSIYLSLIIILLFSAQLSVRQLFMSCMRSSQTLHDRMFEKVAFTNSRFFDLNPNGRILNRFSKDIGSXDELLPPAL-------LSGSGIFILISMTNPLIVVGIVVLLLILLTIRKYYLNASRAVKRLEGITRSPVFSQLASSLDGLTTIRSMKIEEMLIEEFDYLQDIHTSSYYSFLVVNRFFAFCGDLMLSLFTASMVSMFLFYNRDATGGDVGLSLTLSLALCGMIQWGLRQSAEVENFMTSVERVAEYG-DLPKEKGLKGDIKLDPSWPDKGVIEFSNVNLKYDGTTPYVLKG------------------------------LTEP-EGKIFIDGVNICRLSLQDVRKKISIIPQDPLLFKGTIRKNLDPFDEYGELAIWHALEQAKLSVAVSELEGGLETEVSEGGNNFSVGQRQLFCLARAILRKNKVLIMDEATANVDPMTDSLIQEAIRTEFKDCT 1530 HSP 2 Score: 231.106 bits (588), Expect = 2.420e-62 Identity = 121/238 (50.84%), Postives = 157/238 (65.97%), Query Frame = 0
Query: 781 VLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
++ W +R +++VE + +VERV EY L +E E K + WP G VEF MRY V+K ++ + +GI+GRTGAGKSS+ ALFRL EP EG I IDG+D+ ++GL D+RKK++IIPQDP+LF+G++R NLDPF +D ++W ALE A L V L GL V E G N SVGQRQL CLA A+LR+ KVLI+DEATA VD TD LIQ IRK+F+ CT
Sbjct: 1 MIQWGLRQSAEVENFMTSVERVVEYG-ELPKEKGLESDIKLDPSWPDKGVVEFSNVSMRYSQHQPNVLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEP-EGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCT 236 HSP 3 Score: 55.8398 bits (133), Expect = 6.467e-8 Identity = 46/174 (26.44%), Postives = 80/174 (45.98%), Query Frame = 0
Query: 235 NVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEI-----IEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGS-----------YQQLVHQKG 392
+V +++ +PQ + T++ N+ P D+ Y E+ +E L + L GG TE+ E G N S GQ+Q LARA V ++D+ + VD I E + ++ + T + H + + +D I+V+ +G I E G+ + Q+V+Q G
Sbjct: 1415 DVRKKISIIPQDPLLFKGTIRKNL----DPFDE-YGELAIWHALEQAKLSVAVSELEGGLETEVSEGGNNFSVGQRQLFCLARAILRKNKVLIMDEATANVDPMTDSLIQEAIRTE---FKDCTVFTIAHRLYTVMDSDRILVMSDGEIKELGAPLDLLSDPSNIFYQMVNQLG 1580 HSP 4 Score: 52.373 bits (124), Expect = 6.967e-7 Identity = 44/179 (24.58%), Postives = 78/179 (43.58%), Query Frame = 0
Query: 176 VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAF--LGEMEKE----------QGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKV 342
V+ +N + + +P VL + + ++G G+GKSS+ISA L E E E G +++ +++ +PQ + N +++ N+ D + +E L + L G + + E G N S GQ+Q LA A V ++D+ + VD I E +
Sbjct: 50 VEFSNVSMRYSQHQPNVLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEPEGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAI 228
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000000090 (supercontig:LSalAtl2s:LSalAtl2s1014:9799:23913:-1 gene:EMLSAG00000000090 transcript:EMLSAT00000000090 description:"maker-LSalAtl2s1014-snap-gene-0.6") HSP 1 Score: 390.963 bits (1003), Expect = 4.132e-121 Identity = 280/910 (30.77%), Postives = 454/910 (49.89%), Query Frame = 0
Query: 127 MRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDD---NALEHDEKQKD-TPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEM-EKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAI-ISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVG--LSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIV-PVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGES-ITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETI-GNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQE-AEWELP------NKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
MR+P +LP I L Q VS+ RI+ Y+N EE+D N + +D +++ + +S K + +L +I G LTAVVG VGSGKS L++A GE+ ++ +GS + + YV Q W+++AT+++NI FG+ +YQ+++ C L D + + GD T + G LSGGQ+QR+ ARA Y +A VYL+DDPLSA DS++ IF I KG L+ KTR+L+T+ + +P D IIV++ G + E+ S E+V E K+ ++Q S F N + + DN D ++ KI +L + + G+V +++ GY + F V + + +SS N + ++ + Y +Y G+ G +CQ+ + L +++ +L AS H +L +V +P++FF +TP G I+NRF+KD+D D LPN L+ + LGT+I+ + PI A IV P+ +IF + Y+ SR LKR + + + HFG+S + G +TIR +G+E +I+E +D +Q II+ L +RL+ I G I A G S L ++ +L V Q + R + +E +V++ER+KE + Q+ + LP +K ++ ++F+ + +Y + +K+ +++ G+ VG+VGRTG+GKSSL +AL L+E +G I IDG+D+S ++RKK D LF G++R NLDP +D+ +W+ L+ A +K F L GL + E G N+S+ LI I+DEA +A+ LE+++ I T +F T
Sbjct: 1 MRIPFRLLPSCISALSQGIVSIKRIDSYLNREEVDSVKSNDFSKSPRPEDGYSIQVQDCNYSIDKLK--LLKNINFSTRVGELTAVVGKVGSGKSCLLAALCGELNQRGKGSSLINKDLVYVTQNIWLKSATIRDNITFGQPYNSSQYQKVVSLCQLGQDFKDMYRGDLTYLASNGSTLSGGQRQRIGFARAIYQNAQVYLMDDPLSACDSNLKAQIFHNTIGPKGFLQKKTRLLITNQSSLIPLMDRIIVIQNGTVEEKDS-----------------------------------AEEVKSFEIAKKSTKKQGS-------------FHEPPKDNYLHPALDNYDIIER------RKIPFSLYKYYVLNLGTVPFIIALVGYLISQC--FDVCSKLWLSRWTNLSSTNIN---DTNYRHIYNEDTRNMYIVVY-GILG---WCQSLAYFLSVLLINSRSLKASSHFHDVILRKVFGAPLNFFWSTPKGTIINRFSKDMDEADMFLPNTLKNFAYQAVKILGTLIIALIAFPITAFFIVCPLGLIFIEVVKSYLMASRFLKRTSATKLAMVLKHFGDSAVHGGTTIRCYGVESDYIDEHMSLIDEHQSVSLMEIISEAXLFLRLQLIAGTFIGILATALVFFPSEGNSSSLSALSLTSSLTVLQDIFLFTRYAAFIEKAMVSIERIKECEDLIPQDPSSGLLPSIITNGSKRPKNHQSRYYIQFEDFSGKYSSLKNASIKNFTLNVRLGEKVGVVGRTGSGKSSLILALSGLLEVEKGKIFIDGVDMSSGTARNIRKKDI---TDAALFKGSIRYNLDPDDRFTDEYIWSVLDEAQMKEFFVQLPGGLDFSLKENGSNISLAGSNLI-------------IMDEAXSAMTLESEERILNTYFSRFSSST 829 HSP 2 Score: 59.3066 bits (142), Expect = 4.987e-9 Identity = 56/217 (25.81%), Postives = 93/217 (42.86%), Query Frame = 0
Query: 193 LHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNV------VGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQE----IIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVH-QKGDFADFL 398
+ + TL + G VVG GSGKSSLI A G +E E+G + + G + ++ A K +I + P D+ E +++ + LPGG + E G N+S + +++ ++D+ SA+ + I S+ T ++ H I L D I+VL+ G I+E G+ + L+ QK F L
Sbjct: 675 IKNFTLNVRLGEKVGVVGRTGSGKSSLILALSGLLEVEKGKIFIDGVDMSSGTARNIRKKDITDAALFKGSIRYNLDPDDRFTDEYIWSVLDEAQMKEFFVQLPGGLDFSLKENGSNIS-------------LAGSNLIIMDEAXSAMTLESEERILNTYFSR---FSSSTIFVIAHRIQPLLACDKILVLENGTIAEFGNPESLIKSQKSIFKSML 875
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000001655 (supercontig:LSalAtl2s:LSalAtl2s128:1836948:1854487:1 gene:EMLSAG00000001655 transcript:EMLSAT00000001655 description:"augustus_masked-LSalAtl2s128-processed-gene-18.4") HSP 1 Score: 390.578 bits (1002), Expect = 1.311e-116 Identity = 239/727 (32.87%), Postives = 399/727 (54.88%), Query Frame = 0
Query: 325 DPLSAVDSHV-------GKHIFEKVISKKGILEGK-TRVL----VTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEP--LEPSAT-------------KIGTNLI----EKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVW-TEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASL-EDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
DPLS + ++V K I + ++ + + GK T+V+ + H +L + DH I ++G G ++ + + D +D + ++ L+ +G KV E + +T +C+ + N ++ I + V + L P++T K +N+I E+E+ ETG V +Y Y + IG + + Q++S T+ WL+ W + F N++E + Y+ VY GL T++ + + A ++A+K +H +L ++R+ + FFD+TP GRI+NRF+ D D++LP L +L+ G +++ + +P V++P+ + ++ IQ Y SR LKR+ S+S SPIY HF E++ G IRA ++F+ E+E+ V+ NQ Y + A+ WL +RL+ IG+I+ F+ A+ +++N +D+G VGL +SYAL +T L +V ++ E +VAVER +Y + +E+ + N P +WP G VEF+ +RY+ L V+ ++ + + +GIVGRTGAGKSSL ALFRL + G I +DGI + L L D R++ +IPQDP +FSGT+R NLDP+ HSD+E+W +++L++L + S GL + +GG++LS+GQ+QL+CLARA++ KV+ +DEATA+VD ETD LI+ ++ F T
Sbjct: 695 DPLSGI-AYVQQVPWIQNKSIRDNILFGEMYIHGKYTKVIKACCLDHDFKHLHRGDHTIAGEKGAALSGGQKARIALARAIYQD----------KDIYLIDDVFSSLDVNVGY-KVYTEVMLNLLKRKTRILCTHNPQYINDANIVIKIKDGEFESVKQSTHLVPTSTSPDFSYDTSMFDFKDNSNVIDDSVEEEMQETGVVAYRIYKKYWQAIGTYLAPTILISIFLMQVASNTTDLWLSHWVSTDNFQNNTEDT--DHYIYVYSGLAVFHTILTLIRAFLFAYGGIHAAKIIHDLLLGVLLRAKIYFFDSTPAGRILNRFSSDTYAIDDSLPFILNIFLSQIFGVFGRVLVCVYAVPWILIVLLPLGLFYYEIQCKYRPGSRDLKRISSVSLSPIYEHFNETVHGLKIIRASKASQRFLLENEELVECNQKARYAAFSASLWLEIRLQLIGSIVVFSIALISVINFESVDAGLVGLAVSYALGMTXRLAEVVVSFTETEKELVAVERAYDYIDRIYEESYSGVLNMP-YNWPNQGVVEFKDIRLRYKDHLPYVLNKVNFKTKPKEKIGIVGRTGAGKSSLIAALFRLSSFSHGEIMVDGIRIRLLPLIDFRRQFAVIPQDPFIFSGTIRQNLDPYAQHSDQELWDSIKLSYLYNIIYSFGSSGLDTLIGDGGKSLSIGQKQLLCLARAIITSAKVVFIDEATASVDKETDRLIRNVLKTAFNDKT 1406 HSP 2 Score: 251.906 bits (642), Expect = 4.160e-69 Identity = 139/399 (34.84%), Postives = 225/399 (56.39%), Query Frame = 0
Query: 4 GLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMN----------NEELDDNALEHDEKQKDTP-VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNV---VGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLV 388
G+ ++ IP N VI + M KDDRVK+++EI+ G++V+K Y WE F + R+ EI LK +L A+ ++W S P ++++S+F Y + GN L A K F ++ ++ P + PF+I GL++ VS+ R+ ++++ E D+N E + P ++I F + K T L +I + I + V+G VGSGK++ ++A LGE+EK+ G ++V + +AYV Q W+QN ++++NILFG+ +Y ++I+AC L D + L GD T GEKG LSGGQK R++LARA Y D D+YL+DD S++D +VG ++ +V+ +L+ KTR+L TH Y+ + +I +K+G LV
Sbjct: 453 GVGFAILMIPINKVIATKIGSLSGHMMSAKDDRVKIIAEIIEGIRVIKYYCWESFFTDKTNSHRNNEIYYLKWRKYLDAVCVYLWASTPVIISVSTFATYSAL--GNPLTAAKVFTSMALFAMLSGPFNAFPFVINGLIEANVSIKRLARFLSLPSINRIKYFTEYKDENTKASKEIETKIPDIQIMEASFGFTKDCFT-LRNIDVSIKRQEFVGVLGPVGSGKTTFLNAILGELEKQSGKISVRDPLSGIAYVQQVPWIQNKSIRDNILFGEMYIHGKYTKVIKACCLDHDFKHLHRGDHTIAGEKGAALSGGQKARIALARAIYQDKDIYLIDDVFSSLDVNVGYKVYTEVM--LNLLKRKTRILCTHNPQYINDANIVIKIKDGEFESVKQSTHLV 846 HSP 3 Score: 75.8702 bits (185), Expect = 4.644e-14 Identity = 59/213 (27.70%), Postives = 97/213 (45.54%), Query Frame = 0
Query: 190 PTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVG-------------QVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEIL-PGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLV 388
P VL+ + + +VG G+GKSSLI+A G + V G Q A +PQ ++ + T++ N+ D+ + I+ L + + G T IG+ G +LS GQKQ + LARA + A V +D+ ++VD + I + K KT + + H I + +D I V+ G+I E+G + L+
Sbjct: 1232 PYVLNKVNFKTKPKEKIGIVGRTGAGKSSLIAALFRLSSFSHGEIMVDGIRIRLLPLIDFRRQFAVIPQDPFIFSGTIRQNLDPYAQHSDQELWDSIKLSYLYNIIYSFGSSGLDTLIGDGGKSLSIGQKQLLCLARAIITSAKVVFIDEATASVDKETDRLIRNVL---KTAFNDKTVITIAHRIETVLNSDRIFVMSNGQIIEEGKPEDLI 1441
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000000741 (supercontig:LSalAtl2s:LSalAtl2s111:116041:261433:1 gene:EMLSAG00000000741 transcript:EMLSAT00000000741 description:"maker-LSalAtl2s111-snap-gene-2.14") HSP 1 Score: 333.569 bits (854), Expect = 6.864e-96 Identity = 225/735 (30.61%), Postives = 376/735 (51.16%), Query Frame = 0
Query: 146 VSLDRINKYMNNEELDD--NALEHDEK---QKDTPVKITNGIFSWGKSEPTV-LHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLK-EGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVY-GYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGV------------------FGNSSEPQ---------YRNLYLGVY----GGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNI-ITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNKPEEDWPQSGEVEFQKYGMRY 840
VS DRI ++ EE+ D ++++H+ + ++ +++ N W +E L +++ ++ K LTA++G VGSGKS+++ A LGE G +++ G+++Y Q+ W+ + T++ NIL G KRY ++++ C+L DLE P D T +GEKG+ LSGGQK R++LAR+ YS+ DVYLLDDPLSAVDSHVG++++E+ I K L KT +LVTH I YL + ++II+L +G QG+ +L+ + DF FL+ EET+ E+ + L E R R S+ S+ S A I + ++ D P E T+ + ++ GS+ +++Y Y+ + G + + + + Q+ V T++W WT + N+S + + ++Y G+Y G L C S + L +S+ +H M +V+ + +FFD P+GRI+NRF+KDI D+ LP L F + +G LII+ P ++ + II ++ Y+N SR +KRLE I++SP+ S ++ G STIRA LE F +E DI+ ++ R+ ++ I +I + IF N G G++G+ +S ++ + + + W +R +++VE + +VERV EY L E K + WP G ++F ++Y
Sbjct: 1166 VSTDRIQNFLLLEEIGDICSSMKHEPEVRPEESLRIEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECIKK--YLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLLMSERDFKPFLVA-QEEETDSIFHKNELALTPRKSLNIENYM--------RRRQSSVSSI--------GSRATIDTNVMEYNDIPNEGRRTQTTESKVK------GSISVALYKKYFYADGGKWMFFFVYGLNISSQLIFVMTDWWXKQWTNAADARKKFGDIRNQKHFFSSYANTSSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISVRKFIFL----CLKSSRNLHSEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGALDDLLPIALSDTNLIFLNAVGMSGLIISTEPKILIPLLAILIILLALRKYYLNASRSVKRLEGITKSPVISQLSTTLNGISTIRASKLENNFASEFHYLQDIHTAAFFSFQSVTRFFGFWVDGIVSINVXATVVIFVFFNVKG---GDIGISLSLSVLMARXIQWGLRQSAEVENYMTSVERVAEYG-DLPSEKRLTSDKKIDPSWPNKGVIKFHNVKLKY 1867 HSP 2 Score: 323.168 bits (827), Expect = 1.673e-92 Identity = 225/697 (32.28%), Postives = 366/697 (52.51%), Query Frame = 0
Query: 4 GLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAI-INFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVL-PFMIIGLVQVGVSLDRINKYMNNEELDD--NALEHDEKQK---DTPVKITNGIFSWGKSEPTV-LHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLK-EGRISEQGSYQQLVHQKGDFADFLLEYMSEET-----EDEQTLMEIK-MELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIG--W-FGVVAGFAMQLIYQISSVGTNYWLNVWTEGV------FGNSSEPQ---------YRNLYLGVY----GGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAII 663
G AI+++ IP I + ++ D R+++M+EI+ G+KV+K+Y WE FM + + R EI +KKT A + F + S ++ L F + + G V+ ++ F+ N +R+ +++ P I + VS DRI ++ EE+ D ++++H+ + + +++ N W +E L +++ ++ K LTA++G VGSGKS+++ A LGE G +++ G+++Y Q+ W+ + T++ NIL G + KRY ++++ C+L DLE P D T +GEKG+ LSGGQK R++LAR+ YS+ADVYLLDDPLSAVDSHVG+H++E+ I K L KT +LVTH I YL +II+L +G I +QG+ +L+ + DF FL+ EET EDE L K + +E+ + R R S+ S+ S A I + ++ D P E T+ + ++ GS+ +++Y Y G W F V G + ++ Q+ V T++WL WT + N+S + + ++Y G+Y G L C S I+ L +SK +H M +V+ + +FFD P+GRI+NRF+KDI D LP L F + +G LII+ P V++P+ +I
Sbjct: 246 GGAILLVFIPLQTWIGKQFSRLRILIAGKTDKRIRVMNEIIEGMKVIKMYAWEYPFMEVVNETRRDEIQTIKKTYEYKAFNLGFFFTSSRVVLLLIFFLMII---GNEVISSKNIFLIFGLFNTVRLSLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEVSLRIEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECI--KNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLLMSERDFTSFLVA-QEEETDSIFDEDELALTPKKSLNIENYM--------------RRRQSSVSSI--------GSRATIDTNAMEYNDIPNEGRRTQTTESKVK------GSISVALYKKYFYAGGGKWIFFFVYG--LNILSQLLFVSTDWWLKQWTNAADARTNNYANASSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISIRKFLIL----CLKSSKNLHLEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGSLDXLLPLALSDTSLIFLNAVGMFGLIISTEP---KVLIPLGLI 899 HSP 3 Score: 62.7734 bits (151), Expect = 4.369e-10 Identity = 67/262 (25.57%), Postives = 118/262 (45.04%), Query Frame = 0
Query: 741 LETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEW--ELPNKPEEDWPQSGEVEFQKYGMRYRPG-LDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVD 999
L IGN + + IF I GL + L++T + MTS+ +V+ +R++ + L LE+ + + ++PE S +E + ++ D ++++ + + I+G G+GKS++ AL + G I I G K++ Q+P +FSGT+R N+ + K L++ L+ + S D V E G LS GQ+ I LAR++ + V +LD+ +AVD
Sbjct: 344 LMIIGNEVISSKNIFLIF----------GLFNTVRLSLTLFFPNTISMTSEA---LVSTDRIQNFLL-LEEIGDICSSMKHEPEVRPEVSLRIEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYG-------------KISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVD 578 HSP 4 Score: 60.077 bits (144), Expect = 3.711e-9 Identity = 56/217 (25.81%), Postives = 102/217 (47.00%), Query Frame = 0
Query: 786 VRMTSDVETNIVAVERVKEYTLTLEQEAEW--ELPNKPEEDWPQSGEVEFQKYGMRYRPG-LDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVD 999
+ MTS+ +V+ +R++ + L LE+ + + ++PE +S +E + ++ D ++++ + + I+G G+GKS++ AL + G I I G K++ Q+P +FSGT+R N+ + K L++ L + S D V E G LS GQ+ I LAR++ + V +LD+ +AVD
Sbjct: 1158 ISMTSEA---LVSTDRIQNFLL-LEEIGDICSSMKHEPEVRPEESLRIEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYG-------------KISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVD 1357
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000002016 (supercontig:LSalAtl2s:LSalAtl2s1361:43077:48755:-1 gene:EMLSAG00000002016 transcript:EMLSAT00000002016 description:"augustus_masked-LSalAtl2s1361-processed-gene-0.2") HSP 1 Score: 274.633 bits (701), Expect = 2.087e-76 Identity = 182/580 (31.38%), Postives = 296/580 (51.03%), Query Frame = 0
Query: 488 EIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGT--NYWLNVWTEGVFGNSSEPQYRNL--YLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVI--PIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSG----IDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWE-----------------------LPNKPEEDWPQSGE----------VEFQ------KYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
E E GS+ + V Y K G F +AGF + L + + SV ++ L W+ E L Y YG L + + +++ + A ++H M+ +M P+ F+ P+GRI+NR + DI + D +P +++ + SF+ L I P+F +P+ I++++ Y +SR+L+RL+SI+R+P+ SHF ++++G T+RAFG + +FINE +KVD N + RWL V L+ G I F + + + P S +GL ++Y+L V L W+V+ +++E + AVERV EYT +E ++ ++ EED SG+ + F + R PG+ + I Q VGI GR+G+GKS+L + + RL +G+I I+GI+++ + L LRK + IPQD VLFSGT+R NLDP SD+ +W+ L+ A V + DGL V+E G+N S+GQRQ + + +ALLR+ +V+ILDE+T+A+D + + T+ + F+ T
Sbjct: 1271 ENREYGSIDIGVLTVYFKAGGIF--LAGFFVILSFVLQSVKVYMDFLLRDWS------MEEKNSDKLIAYFSFYGSLSVIVILISCVANLIGQLIGARARTKLHNDMIQNIMYCPLELFEAFPIGRIINRISHDIFIVDQKIPPCIQRLI--MLSFVCIAALAXNSIQSPVFLIFALPMISIYWWLXHFYRRSSRELQRLDSITRAPVLSHFSDTLSGLITVRAFGEQTRFINELCEKVDTNTSAFLILQSGCRWLGVYLDAAGAIFVFLSILVNLFFPRKGREVTSSASIGLSVNYSLLVPIYLAWVVKFAANIENYMNAVERVLEYTHFPSEEEDFSEFQAVHASSMNSSRRSFLLRGRGKHDEIEEDVRVSGDFLQNDSEGLIIRFNSVCLAPSFEYRRLPGIQ---QGFSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFEDST 1837 HSP 2 Score: 226.098 bits (575), Expect = 1.004e-60 Identity = 138/434 (31.80%), Postives = 235/434 (54.15%), Query Frame = 0
Query: 30 MKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTV-------YVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMN---------NEELDDNALEHDEKQ-----------------------KDTPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSV--NVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLL--EYMSEETEDEQTLMEIKMELE 420
+ ++D+R+ +E L +K +KL E+ + +I R KE++ L++ + F+W + FL ++S+ V +V ++ N A F ++ L+ + + +SV+P + ++ VS R+ +++N N +L+ + D+++ +T + NG F+W K E VL I LEI GSLT V+G GSGK++LIS+ + EM++ GSV NV VA + Q+ W+ N T+K+NIL G+ K+KRY+++I AC L +D+++LP GD TEIGE+G+ LSGGQ+QR+++AR YS + +D P S++DS + H+FE+ + K + +T L T + +L + DHI+ LK+G I QG+ Q + + L +S ++D + L+E K E
Sbjct: 551 LCSQDNRLFKSTETLASMKTVKLATMEEWALKRIRCARTKELIFLRRDS-------FLWSFMAFLASISTTLVTTLTLGLFVLLEDHN-FTAADLFTSMALLSQLTVCLSVVPVTVPIFIKGKVSTQRLAEFLNRAEVSIYKQNNKLNKHCTYFDDRKDDDEEEEEEEEESEIFIQRAKRLPETCFTVENGTFAWPKCETNVLQSINLEIKTGSLTIVIGPSGSGKTALISSLIEEMDRITGSVKWNVPDTVALLGQRPWLLNTTIKDNILLGRPFKEKRYKKVIAACDLQTDIDLLPHGDDTEIGERGVLLSGGQRQRLAIARCLYSKSYCTFMDAPFSSLDSKITSHVFEEGVLKILLKRRRTVFLTTERLDFLHRADHIVALKDGMIKAQGTIQDVTRLCPELLSTKLSKNRLSRISDDNKGLVEGKTAQE 976 HSP 3 Score: 72.0182 bits (175), Expect = 6.697e-13 Identity = 56/222 (25.23%), Postives = 104/222 (46.85%), Query Frame = 0
Query: 190 PTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVG-------------QVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSD----LEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDF 394
P + +LEIP + G GSGKS+L+ + QGS+ + G V +PQ A + + T+++N+ P++ E+I + +D + P G T + E G N S GQ+Q +++ +A V +LD+ SA+D + + ++ E T + V H ++ + + + ++V+ EGRI E G+ ++L+ + F
Sbjct: 1664 PGIQQGFSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNL----DPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEA---FEDSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGF 1878
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000007660 (supercontig:LSalAtl2s:LSalAtl2s445:12562:17493:1 gene:EMLSAG00000007660 transcript:EMLSAT00000007660 description:"maker-LSalAtl2s445-augustus-gene-0.18") HSP 1 Score: 119.013 bits (297), Expect = 1.134e-27 Identity = 124/478 (25.94%), Postives = 223/478 (46.65%), Query Frame = 0
Query: 564 QAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFAS---VIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGE-SITGASTIRAFGLEKQ----FINESEQKVDINQVCYYPSIIANRWLAVRLETIG-NIITFAAAIFAI--LNPSGIDSGEVGLIISYALNVTQVLNWLVRMT---SDVETNIVAVERVKEYTLTLEQEAEWELPNKPEEDWPQS---GEVEFQKYGMRY--RPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVE-PAEGTIQIDGIDVSQLGLHDLR-KKLTIIPQDPVLFSGTLRINLDPFGI--HSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
Q+ T+ LA + + K + + ++ ++FFD G IV+R + D+ ++ + Q L + A G I+ + + P S VIVP I+ Y+ + ++ ++ ++ + GE I+ T+R F +E + E ++ D N+ + L +I IT+ + + LNP G ++S+ ++V + + +++ + + + R+ EY E +P P G+VEF+ Y RP V+KD I ++V +VG +G GK+++ L R + G+++IDGI++ L LR + I Q+PVLF+ ++ N+ +G +D EV+ A + AH+ FV + DG S + E G +S GQ+Q I +ARALL+ +LILDEAT+A+D E++ ++Q + K +G T
Sbjct: 166 QSICTIAYIYSLACLGERMAASLRKDLFNSIICQDIAFFDEHKTGEIVSRLSADVQEFKSSFKLVISQGLRSSAQASGCIVSMYMISPQMTSAMGVIVPTVIL----GGTYIGSYLRVLSKKAQAQVAKATAVGEECISNIRTVRGFAMEDAEMELYSREVDKTRDFNEALGLGIGVFQGASNFFLNSIVLGTITYGGYLMSDDNLNP--------GQLMSFLVSVQTIQRSITQVSLLFGHLVKGMASGSRIFEYI-----EKVPLIPISGGVKIPYHSFFGDVEFKNITFSYPTRPE-QAVLKDFSLRIPPSKTVALVGTSGGGKTTIAALLERFYDINGGGSLEIDGINIRDLDPSWLRGSAIGYINQEPVLFATSVIENIR-YGRPNATDNEVYEAAKAAHVDDFVRTFPDGYSTILGERGVTVSGGQKQRIAIARALLKNPPILILDEATSALDAESERIVQEALDKLSKGRT 624 HSP 2 Score: 95.5153 bits (236), Expect = 2.707e-20 Identity = 67/241 (27.80%), Postives = 124/241 (51.45%), Query Frame = 0
Query: 176 VKITNGIFSW-GKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEME--KEQGSVNVVG--------------QVAYVPQQAWMQNATVKNNILFGKA-PKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFL 398
V+ N FS+ + E VL D +L IP A+VGT G GK++ I+A L GS+ + G + Y+ Q+ + +V NI +G+ D E +A + + P G +T +GE+G+ +SGGQKQR+++ARA + + +LD+ SA+D+ + I ++ + K + +G+T +++ H ++ + D I V+ +G ++E G++ L + G ++ +
Sbjct: 433 VEFKNITFSYPTRPEQAVLKDFSLRIPPSKTVALVGTSGGGKTT-IAALLERFYDINGGGSLEIDGINIRDLDPSWLRGSAIGYINQEPVLFATSVIENIRYGRPNATDNEVYEAAKAAHVDDFVRTFPDGYSTILGERGVTVSGGQKQRIAIARALLKNPPILILDEATSALDAE-SERIVQEALDK--LSKGRTSLVIAHRLSTIKNADVIAVIDKGVMAEIGTHAALKRKGGIYSRLI 669
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|82231164|sp|Q5F364.1|MRP1_CHICK (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1110.13 bits (2870), Expect = 0.000e+0 Identity = 550/1024 (53.71%), Postives = 739/1024 (72.17%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELD-DNALEHDEKQKDTPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLM------EIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWEL-PNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A+M++ +P NAV+ T+ YQ+ QMK+KD+R+KLM+EIL G+KVLKLY WE +F ++L+IR KE+ VLKK+A+L A+ F W+ PFLVALS+F VYV ++ N+LDAQKAFV+L NI+R P+++LP +I +V+ VSL R+ ++++EELD D+ + + + + N FSW K++P L+ I +P+GSL AVVG VG GKSSL+SA LGEM+K++G V V G +AYVPQQAW+QNAT+++NI+FG+ + RY+ +IEACAL+ DLEILP GD TEIGEKG+NLSGGQKQRVSLARA Y +AD YL DDPLSAVD+HVGKHIFEKVI KGIL+ KTRVLVTH + YLP+ D I+V+ +G ISE GSYQ+L+ Q G FA+FL Y + E E + E K VL + + RQ S + T S ++ S SS A E+ +PL A K L E + A+TG V +VY YMK IG + + + I+S+ +NYWL++WT+ N ++ QY N+ LGVYG LG Q + S+ ++I + AS+ +H +LH V+RSPMSFF+ TP G +V+RF+K+ID D+T+P ++ ++ + + +G I+I+ PI A VI P+ +++ +Q YV TSRQLKRLES+SRSP+YSHF E++ G S IRAF +K+FI +++ KVD NQ YYPSI+ANRWLAVRLE +GN I AA+FA++ + + G +GL +SY+L +T LNWLVRMTSD+ETNIVAVERVKEY +E+EAEW + P WPQ G+VEF+ +G+RYR LDLV+K+I+ I GG+ VGIVGRTGAGKSSLT+ LFR+ E AEG I IDGI+++++GLHDLR K+TIIPQDP+LFSG+LR+NLDPF HSD+++W +LELAHLK FV+SL D L+H+ SEGGENLSVGQRQL+CLARALLRK+K+L+LDEATAAVDLETD+LIQ+TI+ QF+ CT
Sbjct: 467 AGVAVMILLVPINAVMAMKTKTYQVAQMKSKDNRIKLMNEILNGIKVLKLYAWELAFREKVLEIRQKELKVLKKSAYLAAMGTFTWVCAPFLVALSTFAVYVKVNKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVEASVSLKRLRVFLSHEELDPDSIIRGPITNAEGSIVVKNATFSWSKTDPPSLNSINFTVPEGSLIAVVGQVGCGKSSLLSALLGEMDKKEGYVVVKGSIAYVPQQAWIQNATLEDNIIFGREMNESRYKRVIEACALLPDLEILPMGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADTYLFDDPLSAVDAHVGKHIFEKVIGPKGILKNKTRVLVTHAVNYLPQMDTILVMTDGEISEMGSYQELLKQDGAFAEFLRTYANAEQSMESSDASSPSGKEGKPVENGVLVNDATGKLMHRQLSNSSTY---SRETGKSQHQSSTA--------ELQKPL---AEKNSWKLTEADTAKTGRVKATVYWEYMKAIGLYISFLSVFLFMCNHIASLASNYWLSLWTDDPVVNGTQ-QYTNVRLGVYGALGISQGIAVFGYSMAVSIGGIFASRHLHLDLLHNVLRSPMSFFERTPSGNLVSRFSKEIDTIDSTIPPIIKMFMGSTFNVIGACIIILLATPIAAVVIPPLGLVYLLVQRFYVATSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQKRFIKQNDMKVDENQKAYYPSIVANRWLAVRLEFVGNCIVLFAALFAVIARNKLSPGLIGLSVSYSLQITAYLNWLVRMTSDLETNIVAVERVKEYA-EMEKEAEWSIEETAPASTWPQEGKVEFRGFGLRYREDLDLVLKNINITINGGEKVGIVGRTGAGKSSLTLGLFRINEAAEGEIIIDGINIAKIGLHDLRFKITIIPQDPILFSGSLRMNLDPFDQHSDEDIWRSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDNLIQSTIKSQFEECT 1474
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|75072999|sp|Q8HXQ5.1|MRP1_BOVIN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1103.58 bits (2853), Expect = 0.000e+0 Identity = 545/1020 (53.43%), Postives = 743/1020 (72.84%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEH---DEKQKDTPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPN-KPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A+MV+ +P NAV+ T+ YQ+ MK+KD+R+KLM+EIL G+KVLKLY WE +F ++L IR +E+ VLKK+A+L A+ F W+ PFLVALS+F VYV +D N+LDAQKAFV+L NI+R P+++LP +I +VQ VSL R+ ++++E+LD ++++ + + + N F+W +++P LH IT +P+GSL AVVG VG GKSSL+SA L EM+K +G V V G VAYVPQQAW+QN +++ NILFG+ +++ Y+ ++EACAL+ DLEILP GD TEIGEKG+NLSGGQKQRVSLARA Y D+DVYLLDDPLSAVD+HVGKHIFE VI KG+L+ KTR+LVTH I+YLP+ D IIV+ G+ISE GSYQ+L+ + G FA+FL Y S E E Q + L V G K ++ E T +Q S++SS + +SQ + E +P T+ L+E + A+TG V LSVY YMK IG F + L ++S+ +NYWL++WT+ N ++ ++ + L VYG LG Q + S+ ++I + AS+++H +LH V+RSP+SFF+ TP G +VNRF+K++D D+ +P ++ ++ + + +G I+I+ P+ A +I P+ +I+FF+Q YV +SRQLKRLES+SRSP+YSHF E++ G S IRAF +++FI +S+ KVD NQ YYPSI+ANRWLAVRLE +GN I A++FA+++ + +G VGL +SY+L VT LNWLVRM+S++ETNIVAVER+KEY+ T E+EA W++ + P +DWPQ G VEF+ YG+RYR LDLV+K I+ I GG+ VGIVGRTGAGKSSLT+ LFR+ E AEG I ID I+++++GLHDLR K+TIIPQDPVLFSG+LR+NLDPF +SD+EVWT+LELAHLK FV++L D L+H+ +EGGENLSVGQRQL+CLARALLRKTK+L+LDEATAAVDLETDDLIQ+TIR QF CT
Sbjct: 468 AGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKDAGATNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQGQP----EDGLAGVGGPGKEVKQMENGMLVTDTAGK-QMQRQLSSSSSYSRDVSQHHTSTA-ELRKPGPTEETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQ-EHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSET-EKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCT 1479 HSP 2 Score: 74.7146 bits (182), Expect = 2.874e-12 Identity = 98/430 (22.79%), Postives = 181/430 (42.09%), Query Frame = 0
Query: 7 IMVIAIPFNAVIVS-------FTRKY------QLEQMKN--KDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPF------LVALSSFTVYVF---MDGGNV-LDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSV-------------NVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDF 394
I+++A P AVI+ F +++ QL+++++ + +E L GV V++ + ++ F+ Q D++ E + A+ +I+ W++V +V +S + + G V L + TYLN + S + I V+++R+ +Y E+ ++ KD P V+ + + + VL I + I G +VG G+GKSSL E +G + ++ ++ +PQ + + +++ N+ D+ +E L + LP E E G NLS GQ+Q V LARA + +LD+ +AVD I + ++ + T + + H + + +IVL +G I E GS L+ Q+G F
Sbjct: 1106 IILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQS-DLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNI-------VAVERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQ---FDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRGLF 1520
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|52783101|sp|O35379.1|MRP1_MOUSE (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1093.95 bits (2828), Expect = 0.000e+0 Identity = 534/1020 (52.35%), Postives = 740/1020 (72.55%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHD--EKQKDTPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICS-VQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWEL-PNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A+M++ +P NAV+ T+ YQ+ MK+KD+R+KLM+EIL G+KVLKLY WE +F +++ IR +E+ VLKK+A+L A+ F W+ PFLVALS+F V+V +D N+LDA+KAFV+L NI+R P+++LP +I +VQ VSL R+ ++++EEL+ +++E + + + + N F+W + EP L+ IT IP+G+L AVVG VG GKSSL+SA L EM+K +G V + G VAYVPQQAW+QN +++ NILFG ++ Y+ ++EACAL+ DLEILP GD TEIGEKG+NLSGGQKQRVSLARA YS++D+YL DDPLSAVD+HVGKHIFEKV+ G+L+ KTR+LVTHGI+YLP+ D IIV+ G+ISE GSYQ+L+ + G FA+FL Y + E ++ E + V G K + E T+++ +Q SN+SS + SQ + + E + A + L+E + A+TG V LSVY YMK IG F + L +S++ +NYWL++WT+ + RN L VYG LG Q + S+ ++I + AS+++H +L+ V+RSPMSFF+ TP G +VNRF+K++D D+ +P ++ ++ + S +G +I+I+ PI A +I P+ +++FF+Q YV +SRQLKRLES+SRSP+YSHF E++ G S IRAF +++FI++S+ KVD NQ YYPSI+ANRWLAVRLE +GN I AA+FA+++ + +G VGL +SY+L +T LNWLVRM+S++ETNIVAVER+KEY+ T E+EA W++ P WP SG VEF+ Y +RYR LDLV+K I+ I+GG+ VGIVGRTGAGKSSLT+ LFR+ E AEG I IDG++++++GLH+LR K+TIIPQDPVLFSG+LR+NLDPF +SD+EVW ALELAHLK FV++L D L+H+ +EGGENLSVGQRQL+CLARALLRKTK+L+LDEATAAVDLETD+LIQ+TIR QF+ CT
Sbjct: 469 AGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVKNATFTWARGEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFLRTYANAE-------QDLASEDDSVSGSGKESKPVE--NGMLVTDTVGKHLQRHLSNSSSHSGDTSQQH-SSIAELQKAGAKEETWKLMEADKAQTGQVQLSVYWNYMKAIGLFITFLSIFLFLCNHVSALASNYWLSLWTDDPPVVNGTQANRNFRLSVYGALGILQGAAIFGYSMAVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSET-EKEAPWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCT 1477 HSP 2 Score: 75.8702 bits (185), Expect = 1.284e-12 Identity = 104/445 (23.37%), Postives = 185/445 (41.57%), Query Frame = 0
Query: 7 IMVIAIPFNAVIVS-------FTRKY------QLEQMKN--KDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLD-RINKYMN-----NEELDDNAL------EHDEKQKDTPVKI--TNGIFSW---GKSE------------PTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSV-------------NVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDF 394
I+++A P AVI+ F +++ QL+++++ + +E L GV V++ + ++ F+ Q D++ E + A+ +I+ W++V GN + A + I R +S GLV + VS +I Y+N + E++ N + E+ E +K+ P +I T +W G+ E VL I + I G +VG G+GKSSL E +G + N+ ++ +PQ + + +++ N+ D+ +E L + LP E E G NLS GQ+Q V LARA + +LD+ +AVD I + ++ E T + + H + + +IVL +G + E G+ +L+ Q+G F
Sbjct: 1104 IILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQS-DLKVDE----NQKAYYPSIVANRWLAVRLECV------------GNCIVLFAALFAV----ISRHSLSA------GLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQ---FEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQRGIF 1518
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|75071939|sp|Q6UR05.1|MRP1_CANFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1091.26 bits (2821), Expect = 0.000e+0 Identity = 541/1036 (52.22%), Postives = 735/1036 (70.95%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKD----TPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMS---EETEDEQTL------------MEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPN-KPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A+M++ +P NAV+ T+ YQ+ MK+KD+R+KLM+EIL G+KVLKLY WE +F ++L IR +E+ VLKK+A+L A+ F W+ PFLVALS+F VYV +D N+LDAQKAFV+L NI+R P+++LP +I +VQ VSL R+ ++++EEL+ +++E KD + + N F+W +S+P L IT IP+GSL AVVG VG GKSSL+SA L EM+K +G V + G VAYVPQQAW+QN +++ NILFG+ +++ Y+ +IEACAL+ DLEILP GD TEIGEKG+NLSGGQKQRVSLARA Y D+D+YL DDPLSAVD+HVGKHIFE VI KG+L+ KTR+LVTH I+YLP+ D IIV+ G+ISE GSYQ+L+ + G FA+FL Y S E+ E + L ME M + DV G++ +Q SN+SS + +S+ + + + L+E + A+TG V LSVY YMK IG F + L ++S+ +NYWL++WT+ N ++ ++ + L VYG LG Q + S+ ++I + AS+++H +L V+RSPMSFF+ TP G +VNRF+K++D D+ +P ++ ++ + + +G I+I+ PI + +I P+ +I+FF+Q YV +SRQLKRLES+SRSP+YSHF E++ G S IRAF +++FI +S+ KVD NQ YYPSI+ANRWLAVRLE +GN I AA+F++++ + +G VGL +SY+L VT LNWLVRM+S++ETNIVAVER+KEY+ T E+EA W++ P WPQ G VEF+ YG+RYR LDLV+K I+ I GG+ VGIVGRTGAGKSSLT+ LFR+ E AEG I ID I+++++GLHDLR K+TIIPQDPVLFSG+LR+NLDPF +SD+EVWT+LELAHLK FV+ L D L+ + +EGGENLSVGQRQL+CLARALLRKTK+L+LDEATAAVDLETDDLIQ+TIR QF CT
Sbjct: 468 AGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIER-RPVKDGGGANSITVKNATFTWARSDPPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRLLVTHSISYLPQVDVIIVMTGGKISEMGSYQELLARDGAFAEFLRTYASGDQEQAEQDDGLTGVSSPGKEVKQMENGMLVTDVAGKQ--------------------LQRQLSNSSSYSGDVSRHHTSTAELQKAGPKNEDAWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQ-EHTKIRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHVDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIASIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFSVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSET-EKEAPWQIQEMAPPSTWPQVGRVEFRDYGLRYRENLDLVLKHINITINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRVKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCT 1480 HSP 2 Score: 67.781 bits (164), Expect = 4.189e-10 Identity = 96/423 (22.70%), Postives = 174/423 (41.13%), Query Frame = 0
Query: 7 IMVIAIPFNAVIVSFTRKY------QLEQMKN--KDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPF---------LVALSSFTVYVFMDGGNV-LDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNV-------VG------QVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDF 394
I I IP +I F +++ QL+++++ + +E L GV V++ + ++ F+ Q D++ E + A+ +I+ W++V AL S + G V L + TYLN + S + I V+++R+ +Y E+ ++ P V+ + + ++ VL I + I G +VG G+GKSSL E +G + + +G ++ +PQ + + +++ N+ D+ +E L + LP E E G NLS GQ+Q V LARA + +LD+ +AVD I + ++ + T + + H + + +IVL +G I E G L+ Q+G F
Sbjct: 1114 IASIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQS-DLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFSVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNI-------VAVERLKEYSETEKEAPWQIQEMAPPSTWPQVGRVEFRDYGLRYRENLDLVLKHINITINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRVKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQ---FDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGQPSDLLQQRGLF 1521
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|85701143|sp|Q8CG09.2|MRP1_RAT (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1087.4 bits (2811), Expect = 0.000e+0 Identity = 538/1023 (52.59%), Postives = 738/1023 (72.14%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKD----TPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICS-VQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGT-NLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWEL-PNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A+M++ +PFNAV+ T+ YQ+ MK+KD+R+KLM+EIL G+KVLKLY WE +F ++++IR +E+ VLKK+A+L A+ F W+ PFLVALS+F V+V +D N+LDA+KAFV+L NI+R P+++LP +I +VQ VSL R+ ++++EEL+ +++E KD + + N F+W + EP L+ IT IP G+L AVVG VG GKSSL+SA L EM+K +G V + G VAYVPQQAW+QN +++ NILFG+ ++ Y+ ++EACAL+ DLEILP GD TEIGEKG+NLSGGQKQRVSLARA Y ++D+YLLDDPLSAVD+HVGKHIFEKV+ G+L+ KTR+LVTHGI+YLP+ D IIV+ G+ISE GSYQ+L+ + G FA+F+ Y EQ L V G K + E T+++ +Q SN+SS + + +Q + + L+ S K T L+E + A+TG V LSVY YMK IG + L +S++ +NYWL++WT+ + + RN L VYG LG Q + S+ ++I + AS+++H +L V+RSPMSFF+ TP G +VNRF+K++D D+ +P ++ ++ + S +G +I+I+ PI A +I P+ +++FF+Q YV +SRQLKRLES+SRSP+YSHF E++ G S IRAF +++FI +S+ KVD NQ YYPSI+ANRWLAVRLE +GN I AA+FA+++ + +G VGL +SY+L +T LNWLVRM+S++ETNIVAVER+KEY+ T E+EA W++ P WP SG VEF+ Y +RYR LDLV+K I+ I+GG+ VGIVGRTGAGKSSLT+ LFR+ E AEG I IDGI+++++GLH+LR K+TIIPQDPVLFSG+LR+NLDPF +SD+EVW ALELAHLK FV++L D L+H+ +EGGENLSVGQRQL+CLARALLRKTK+L+LDEATAAVDLETDDLIQ+TIR QF+ T
Sbjct: 469 AGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIER-WSIKDGGGMNSITVKNATFTWARDEPPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFVRTY----ANTEQDLASEDDSKNGVSGLGKESKPVE--NGILVTDAVGKPLQRHLSNSSSHSVVTNQQHSSTAE--LQKSGVKEETWKLMEADKAQTGQVKLSVYWNYMKAIGLCISFLSIFLFLCNHVSALASNYWLSLWTDDRPAVNGTQENRNFRLSVYGALGILQGVAVFGYSMAVSIGGIFASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSET-EKEASWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDST 1481 HSP 2 Score: 74.7146 bits (182), Expect = 3.614e-12 Identity = 64/266 (24.06%), Postives = 112/266 (42.11%), Query Frame = 0
Query: 146 VSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSV-------------NVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDF 394
V+++R+ +Y E+ ++ P V+ + + + VL I + I G +VG G+GKSSL E +G + N+ ++ +PQ + + +++ N+ D+ +E L + LP E E G NLS GQ+Q V LARA + +LD+ +AVD I + ++ E T + + H + + +IVL +G I E G+ +L+ Q+G F
Sbjct: 1260 VAVERLKEYSETEKEASWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQ---FEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQRGVF 1522
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|218526606|sp|B2RX12.1|MRP3_MOUSE (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1083.94 bits (2802), Expect = 0.000e+0 Identity = 534/1027 (52.00%), Postives = 724/1027 (70.50%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDE-----QTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIY---QISSVGTNYWLNVWTEGV--FGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWEL-PNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A++V+ IP N + + YQ++QMK KD R+KLMSEIL G+KVLKLY WE SF+ Q+ IR E+ +L+K A+L AI F+WI PFLV L + VYV++D NVLDA+KAFV+L+ NI+++P+++LP +I GL Q VSL RI ++N ELD +E + I NG F+W + P LH + ++IPKG+L AVVG VG GKSSL+SA LGEMEK +G V+V G VAYVPQQAW+QN T++ N+LFG+ KRYQ+ +E CAL++DL++LPGGD TEIGEKGINLSGGQ+QRVSLARA YSDA+++LLDDPLSAVDSHV KHIF++VI +G+L GKTRVLVTHGI++LP+TD IIVL G++SE G Y L+ G FA+FL Y +E +++ Q E + LED L + E R + + + S S N + + + + +++ + TK LI++EIAETG+V LSVY Y K++G + ++ L+Y +++G N WL+ W+ G ++ R LGVY LG Q ML + + + + A++ +H+ +LH +RSP SFFDTTP GRI+NRF+KDI V D L + LN+F + + TI++I+ P+F V++P+A+++ F+Q YV TSRQLKRLESISRSPI+SHF E++TG S IRA+G + F S+ KVD NQ YP I +NRWL V +E +GN + AA+FA++ + ++ G VGL +SYAL VT LNW++RM SD+E+NI+AVERVKEY+ T + EA W + N+ E WP G VEF+ Y +RYRPGL+LV+K++ H+QGG+ VGIVGRTGAGKSS+T+ LFR++E AEG I IDG++V+ +GLHDLR +LTIIPQDP+LFSGTLR+NLDPFG +S++++W ALEL+HL TFV+S GL Q +EGG+NLSVGQRQL+CLARALLRK++VL+LDEATAA+DLETDDLIQ TIR QF+ CT
Sbjct: 453 AGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISPGYAITIHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLEDTLSTHTDLTDNEPAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTKETGALIKEEIAETGNVKLSVYWDYAKSMG---LCTTLSICLLYGGQSAAAIGANVWLSAWSNDAEEHGQQNKTSVR---LGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKT-KTEAPWVVESNRAPEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCT 1472
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|75072869|sp|Q864R9.1|MRP1_MACFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1080.86 bits (2794), Expect = 0.000e+0 Identity = 539/1035 (52.08%), Postives = 736/1035 (71.11%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQK--DT-PVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETED---------------EQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWEL-PNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A+MV+ +P NAV+ T+ YQ+ MK+KD+R+KLM+EIL G+KVLKLY WE +F ++L IR +E+ VLKK+A+L A+ F W+ PFLVAL +F VYV +D NVLDAQKAFV+L NI+R P+++LP +I +VQ VSL R+ ++++EEL+ +++E + DT + + N F+W +S+P L+ IT IP+G+L AVVG VG GKSSL+SA L EM+K +G V + G VAYVPQQAW+QN +++ NILFG ++ Y+ +I+ACAL+ DLEILP GD TEIGEKG+NLSGGQKQRVSLARA Y +AD+YL DDPLSAVD+HVGKHIFE VI KG+L+ KTR+LVTH ++YLP+ D IIV+ G+ISE GSYQ+L+ + G FA+FL Y S E E E ME M + D G ++ +RQ S + + S S +S A + +D + + L+E + A+TG V LSVY YMK IG F + + ++++ +NYWL++WT+ N ++ ++ + L VYG LG Q + S+ ++I + AS+ +H +LH ++RSPMSFF+ TP G +VNRF+K++D D+ +P ++ ++ + + +G I+I+ PI A +I P+ +I+FF+Q YV +SRQLKRLES+SRSP+YSHF E++ G S IRAF +++FI++S+ KVD NQ YYPSI+ANRWLAVRLE +GN I AA+FA+++ + +G VGL +SY+L VT LNWLVRM+S++ETNIVAVER+KEY+ T E+EA W++ P +WPQ G VEF+ Y +RYR LD V++ I+ I GG+ VGIVGRTGAGKSSLT+ LFR+ E AEG I IDGI+++++GLHDLR K+TIIPQDPVLFSG+LR+NLDPF +SD+EVWT+LELAHLK FV++L D L H+ +EGGENLSVGQRQL+CLARALLRKTK+L+LDEATAAVDLETDDLIQ+TIR QF+ CT
Sbjct: 468 AGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALCTFAVYVTIDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGDTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVALKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQDPEDNGVTGVSGPGKEAKQMENGMLVTDSAG-----KQLQRQLSSSSSYS-----GDVSRQHNSTAELQKDGAKKEET----------WKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFICNHVAALASNYWLSLWTDDPIVNGTQ-EHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSET-EKEAPWQIQETAPPSNWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCT 1480 HSP 2 Score: 77.0258 bits (188), Expect = 6.522e-13 Identity = 95/423 (22.46%), Postives = 173/423 (40.90%), Query Frame = 0
Query: 7 IMVIAIPFNAVIVSFTRKY------QLEQMKN--KDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVP----------FLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVG-------------QVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDF 394
I I IP +I F +++ QL+++++ + +E L GV V++ + ++ F+ Q D++ E + A+ +I+ W++V F + + + G L + TYLN + S + I V+++R+ +Y E+ ++ + P V+ N + + VL I + I G +VG G+GKSSL E +G + + G ++ +PQ + + +++ N+ D+ +E L + LP E E G NLS GQ+Q V LARA + +LD+ +AVD I + ++ E T + + H + + +IVL +G I E G+ L+ Q+G F
Sbjct: 1114 IAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQS-DLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNI-------VAVERLKEYSETEKEAPWQIQETAPPSNWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQ---FEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLF 1521
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|296439301|sp|P33527.3|MRP1_HUMAN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1080.09 bits (2792), Expect = 0.000e+0 Identity = 544/1023 (53.18%), Postives = 740/1023 (72.34%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKD----TPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICS-VQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGT-NLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWEL-PNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A+MV+ +P NAV+ T+ YQ+ MK+KD+R+KLM+EIL G+KVLKLY WE +F ++L IR +E+ VLKK+A+L A+ F W+ PFLVAL +F VYV +D N+LDAQ AFV+L NI+R P+++LP +I +VQ VSL R+ ++++EEL+ +++E KD + + N F+W +S+P L+ IT IP+G+L AVVG VG GKSSL+SA L EM+K +G V + G VAYVPQQAW+QN +++ NILFG ++ Y+ +I+ACAL+ DLEILP GD TEIGEKG+NLSGGQKQRVSLARA YS+AD+YL DDPLSAVD+HVGKHIFE VI KG+L+ KTR+LVTH ++YLP+ D IIV+ G+ISE GSYQ+L+ + G FA+FL Y S TE EQ E + V G K ++ E T+S +Q S++SS + IS+ + + E + A K T L+E + A+TG V LSVY YMK IG F + + +S++ +NYWL++WT+ N ++ ++ + L VYG LG Q + S+ ++I + AS+ +H +LH ++RSPMSFF+ TP G +VNRF+K++D D+ +P ++ ++ + + +G I+I+ PI A +I P+ +I+FF+Q YV +SRQLKRLES+SRSP+YSHF E++ G S IRAF +++FI++S+ KVD NQ YYPSI+ANRWLAVRLE +GN I AA+FA+++ + +G VGL +SY+L VT LNWLVRM+S++ETNIVAVER+KEY+ T E+EA W++ P WPQ G VEF+ Y +RYR LD V++ I+ I GG+ VGIVGRTGAGKSSLT+ LFR+ E AEG I IDGI+++++GLHDLR K+TIIPQDPVLFSG+LR+NLDPF +SD+EVWT+LELAHLK FV++L D L H+ +EGGENLSVGQRQL+CLARALLRKTK+L+LDEATAAVDLETDDLIQ+TIR QF+ CT
Sbjct: 468 AGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIER-RPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYAS--TEQEQDAEE--NGVTGVSGPGKEAKQME--NGMLVTDSAGKQLQRQLSSSSSYSGDISRHH-NSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQ-EHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSET-EKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCT 1480 HSP 2 Score: 76.2554 bits (186), Expect = 1.022e-12 Identity = 97/423 (22.93%), Postives = 173/423 (40.90%), Query Frame = 0
Query: 7 IMVIAIPFNAVIVSFTRKY------QLEQMKN--KDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPF---------LVALSSFTVYVFMDGGNV-LDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVG-------------QVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDF 394
I I IP +I F +++ QL+++++ + +E L GV V++ + ++ F+ Q D++ E + A+ +I+ W++V AL + + G V L + TYLN + S + I V+++R+ +Y E+ ++ P V+ N + + VL I + I G +VG G+GKSSL E +G + + G ++ +PQ + + +++ N+ D+ +E L + LP E E G NLS GQ+Q V LARA + +LD+ +AVD I + ++ E T + + H + + +IVL +G I E G+ L+ Q+G F
Sbjct: 1114 IAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQS-DLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNI-------VAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQ---FEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLF 1521 HSP 3 Score: 56.9954 bits (136), Expect = 8.324e-7 Identity = 75/370 (20.27%), Postives = 154/370 (41.62%), Query Frame = 0
Query: 638 SFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQF------INESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQV-LNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVW-TALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVD 999
S L + +++ ++P+ A + + + Q+ ++ S+ E + G ++ + E F I + E KV + + Y ++ W+ + + TF A++ ++ + I + + N+ + LN L + S + V+++R++ + E E + + +P +D + + + + + I I G V +VG+ G GKSSL AL ++ EG + I G + +PQ + + +LR N+ FG ++ + + ++ L + L G ++ E G NLS GQ+Q + LARA+ + + D+ +AVD
Sbjct: 465 SVLAGVAVMVLMVPVNAVMAMK-------------TKTYQVAHMK--SKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKV-LKKSAYLSAVGTFTWVCTPF--LVALCTF--AVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPD-SIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKG-------------SVAYVPQQAWIQNDSLRENI-LFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVD 799
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|6016599|sp|O88563.1|MRP3_RAT (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=MRP-like protein 2; Short=MLP-2; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1077.77 bits (2786), Expect = 0.000e+0 Identity = 532/1027 (51.80%), Postives = 718/1027 (69.91%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDE-----QTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIY---QISSVGTNYWLNVWTEGV--FGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWEL-PNKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A++V+ IP N + + YQ++QMK KD R+KLMSEIL G+KVLKLY WE +F+ Q+ IR E+ +L+K A+L AI F+W+ PF+V L + VYV +D NVLDA+KAFV+L+ NI+++P+++LP +I G+ Q VSL RI ++N +ELD +E + I NG FSW K P LH I ++IPKG+L AVVG VG GKSSL+SA LGEMEK +G+V+V G VAYVPQQAW+QN T++ N+LFG+ KRYQ+ +E CAL++DL++LPGGD TEIGEKGINLSGGQ+QRVSLARA YSDA+++LLDDPLSAVDSHV KHIF++VI +G+L GKTRVLVTHGI++LP+TD IIVL +G+I+E G Y +L+ G FA+FL Y +E ++ Q E + LED L + E R + + + S S N + + +++ + + TK LI++EIAETG+V LSVY Y K++ G+ + L+Y ++G N WL+ WT V G + R LGVY LG Q ML + + + + A++ +H +LH +R+P SFFDTTP GRI+NRF+KDI V L + N+F + + TI++I+ P+F V++P+A+ + F+Q YV TSRQLKRLES+SRSPI+SHF E++TG S IRA+G + F S+ KVD NQ YP I +NRWL V +E +GN + +A+FA++ + ++ G VGL +SYAL VT LNW++R SD+E+NI+AVERVKEY+ T E EA W L N+ E WP+SG VEF+ Y +RYRPGL+LV+K++ H+QGG+ VGIVGRTGAGKSS+T+ LFR++E AEG I IDG++V+ +GLHDLR +LTIIPQDP+LFSGTLR+NLDPFG +SD+++W LEL+HL FV+S GL Q SEGG+NLSVGQRQL+CLARALLRK++VL+LDEATAA+DLETDDLIQ TIR QF+ CT
Sbjct: 452 AGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDELDPQCVERKTISPGRAITIHNGTFSWSKDLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTEPAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKSV---GLCTTLFICLLYAGQNAVAIGANVWLSAWTNDVEEHGQQNNTSVR---LGVYATLGILQGLLVMLSAFTMVVGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNCVVLFSALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSKT-ETEAPWVLESNRAPEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCT 1471
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|6920069|sp|O15438.3|MRP3_HUMAN (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multi-specific organic anion transporter D; Short=MOAT-D; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1067.76 bits (2760), Expect = 0.000e+0 Identity = 533/1034 (51.55%), Postives = 722/1034 (69.83%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEE----TEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDE----------VDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIY---QISSVGTNYWLNVWTEGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELP-NKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+G+A MV+ IP N + R +Q++QMK KD R+KLMSEIL G+KVLKLY WE SF+ Q+ IR E+ +L+ A+L F W+ PFLV L + VYV++D NVLDA+KAFV+++ NI+R+P+++LP +I L Q VSL RI ++++ EELD ++E + I +G F+W + P LH + +++PKG+L AVVG VG GKSSL+SA LGEMEK +G V++ G VAYVPQQAW+QN T++ N+LFGKA KRYQ+ +EACAL++DLE+LPGGD TEIGEKGINLSGGQ+QRVSLARA YSDAD++LLDDPLSAVDSHV KHIF+ VI +G+L GKTRVLVTHGI++LP+TD IIVL +G++SE G Y L+ + G FA+FL Y +E ED T +E + E +L E+ + + + T VQ F S+ +S D + E ++ + K L ++E A G+V LSV+ Y K + G+ A+ L+Y +++G N WL+ WT +S + +L LGVY LG Q F ML ++ +A + A++ +H+ +LH +RSP SFFDTTP GRI+N F+KDI V D L + LN+F + + T+++I+ P+F VI+P+A+++ +Q Y TSRQLKRLES+SRSPIYSHF E++TGAS IRA+ + F S+ KVD NQ YP II+NRWL++ +E +GN + AA+FA++ S ++ G VGL +SY+L VT LNW++RM SD+E+NIVAVERVKEY+ T E EA W + ++P E WP GEVEF+ Y +RYRPGLDLV++D+ H+ GG+ VGIVGRTGAGKSS+T+ LFR++E A+G I+IDG++V+ +GLHDLR +LTIIPQDP+LFSGTLR+NLDPFG +S++++W ALEL+HL TFV+S GL Q SEGGENLSVGQRQL+CLARALLRK+++L+LDEATAA+DLETD+LIQ TIR QF CT
Sbjct: 454 AGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYAPDEDQGHLEDSWTALEGAEDKEALLIEDTLSNHTDLTDNDPVTY---VVQKQFMRQLSA---LSSDGEGQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWDYAKAV---GLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQ-NNTSLRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKT-ETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCT 1476
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|817061679|ref|XP_012252454.1| (multidrug resistance-associated protein 1 isoform X3 [Athalia rosae]) HSP 1 Score: 1202.96 bits (3111), Expect = 0.000e+0 Identity = 594/1040 (57.12%), Postives = 772/1040 (74.23%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWG--KSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSE------ETEDEQTLMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAIISQDNVDE------------VDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWTEG---VFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNK-PEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+GLA+M+I IP NAVI + T+ Q+ QMK+KDDRVKLM+E+L G+KVLKLY WE SF QIL IR+KEI VLK+ A+L A +F+W PFLV+L SF YV D NVLD+ AFV+L+ NI+R P+S+LP MI +VQ VS+ RIN++MN EELD N ++HD+ + + P+ I NG F+WG +SE VL +I L++ +G L A+VG+VGSGKSSL+SA LGEM++ G VN G +AYV QQAW+QNAT+++NILFGK Y +IEACAL DL++LP GD TEIGEKGINLSGGQKQRVSLARA Y+DADVY +DDPLSAVDSHVGKHIFE VI GIL+ KTRVLVTHGITYLP+ D+IIVLK+G ++EQG+Y+QL+ +KG FA+FL++++ E ++ E L EIK +LE +G ++++Q+ R S+ +ES S S + ++ Q ++D ++ L+P K G LIE E AETGSV VY +Y+++IGWF ++ M ++Q S+G+N WL W++ V ++ R++YLGVYG LG QAF++ L + + A+++MH ML+ V+R+P++FFDTTP+GRI++RFAKD+DV D +LP + + T+++I PIF +VI+P+ II++F+Q YV TSRQLKRLES+SRSPIYSHFGES+TGA TIRA+G++ +FI+ESE KVD+NQVCYYPSIIANRWLAVRLE +GN+I F +A+FA+L + + +G VGL +SYAL +TQ LNWLVRMTSDVETNIVAVER+KEY T QEA WE+P++ P +WP G VEF+ Y +RYR GLDLV++ + + GG+ VGIVGRTGAGKSSLT++LFR++E A+G I ID +D+S +GLH LR +LTIIPQDPVLFSGTLR+NLDPFG +SD +VW ALE AHLK FV L GLSH V+EGG+NLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQ TIR++F+ CT
Sbjct: 449 AGLAVMIILIPINAVIANKTKTLQIRQMKSKDDRVKLMNEVLNGIKVLKLYAWEPSFEQQILKIRNKEIQVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLSDEKNVLDSSTAFVSLSLFNILRFPLSMLPMMISNMVQASVSVKRINRFMNTEELDPNNVQHDQSELN-PLIIENGTFTWGAEESEKPVLRNINLQVQQGHLVALVGSVGSGKSSLVSALLGEMDRISGRVNTKGSIAYVSQQAWIQNATLQDNILFGKTLDKPLYNRVIEACALKPDLDMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNDADVYFMDDPLSAVDSHVGKHIFENVIGPTGILKKKTRVLVTHGITYLPEVDNIIVLKDGEVTEQGTYKQLLEKKGAFAEFLVQHLQEVGNLEADSVSEADLDEIKQQLESTMGADELQQKLSRAISKV-SESHSDSGSLHEKHSINGSLGRQHSIDSQHSLTLHRGNSVKEKELQPQ--KAGEKLIEIEKAETGSVKWRVYSHYLRSIGWFLSISTIVMNAVFQTFSIGSNVWLTAWSDDNTTVVNGVTDTSKRDMYLGVYGALGCGQAFASFLCDLAPQLGCWLATRRMHILMLYGVLRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPQQISDSNYCLFEVIATVVVISYSTPIFLTVILPIGIIYYFVQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAPTIRAYGVQDRFISESEHKVDVNQVCYYPSIIANRWLAVRLEMVGNLIIFFSALFAVLQRNTLSAGFVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGET-PQEAPWEIPDRTPPPEWPTEGRVEFRDYKVRYREGLDLVLRGLTFTVNGGEKVGIVGRTGAGKSSLTLSLFRIIEAADGKIFIDDLDISDMGLHALRSRLTIIPQDPVLFSGTLRLNLDPFGHYSDDDVWRALEHAHLKQFVKGLPTGLSHGVTEGGDNLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQQTIREEFKDCT 1483 HSP 2 Score: 68.9366 bits (167), Expect = 6.434e-8 Identity = 57/214 (26.64%), Postives = 99/214 (46.26%), Query Frame = 0
Query: 192 VLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNV-------------VGQVAYVPQQAWMQNATVKNNI-LFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQK 391
VL +T + G +VG G+GKSSL + +E G + + ++ +PQ + + T++ N+ FG D ++ + E L ++ LP G + + E G NLS GQ+Q + LARA V +LD+ +AVD I + + + + T + + H + + +D +IVL +G I+E S L+ +K
Sbjct: 1312 VLRGLTFTVNGGEKVGIVGRTGAGKSSLTLSLFRIIEAADGKIFIDDLDISDMGLHALRSRLTIIPQDPVLFSGTLRLNLDPFGHYSDDDVWRAL-EHAHLKQFVKGLPTGLSHGVTEGGDNLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQQTIREE---FKDCTVLTIAHRLNTILDSDRVIVLDKGFITEFDSPDALLQKK 1521
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|936574281|ref|XP_014219238.1| (multidrug resistance-associated protein 1 isoform X3 [Copidosoma floridanum]) HSP 1 Score: 1199.5 bits (3102), Expect = 0.000e+0 Identity = 580/1038 (55.88%), Postives = 770/1038 (74.18%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWGKS--EPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQT---LMEIKMELEDVLGEEKVKQEFERQQSRAR-----TESICSVQS--------AFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWT---EGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNK-PEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
SGLA+M+I IP NA++ R Q++QMKNKDDRVKLM+E+L G+KVLKLY WE SF QIL IR+KEI VLK+ A++ A +F+W PF+V+L SF +V +D NVLD++ AFV+L+ NI+R P+S+LP M+ +VQ VS+ RINK+MN+EELD N ++H E + P+ I NG F+W E +L +I L+I +G L A+VG+VGSGKSSLISA LGEMEK G VN G++AYV QQAW+QNAT+++NILFG Y ++EACAL D ++LP GD TEIGEKGINLSGGQKQRVSLARA Y++AD+Y LDDPLSAVDSHVGKHIFE +I +G+++ KTR+LVTHGITYLP+ DHIIVLK+G ISE G+Y++L+ ++G FADFL++++ E DE++ LMEIK +LE+ +G E+++Q+ + ++RA + SI +S +++ S +++ +NV E+++ + K G LIE E AETGSV +VY +Y+++IGWF V+ M ++Q S+ N WL+ W+ E V ++ +N+YLGVYG G QA ++ + + A++QMH M+ V+R+P++FFDTTP+GRI++RFAKD+DV D +LP + + + T+++I P+F SVIVP+ ++++FIQ YV TSRQLKRLES+SRSPIYSHFGES+TGA IRA+G++ +F+NESE +VD NQVCYYPSIIANRWLAVRLE +GN+I F +A+FA+L+ + +G VGL ISYAL +TQ LNWLVRMTSDVETNIVAVER+KEY+ T QEA WE+P++ P +DWP G VEF Y +RYR GLDLV+ + + GG+ +GIVGRTGAGKSSLT+ALFR++E A G I ID +D+S+LGLH LR +LTIIPQDPVLFSG+LR+NLDPF SD ++W ALE AHLK FV L + L+H+V+EGG+NLSVGQRQL+CLARALLRKTKVLILDEATAAVDLETDDLIQ TIR++F+ CT
Sbjct: 460 SGLAVMIILIPVNALLAGKVRNLQIKQMKNKDDRVKLMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVSLVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQH-ETSEVNPIVIENGNFAWDSEHIEKPMLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKGKIAYVSQQAWIQNATLQDNILFGSPFNKALYHRVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSRGLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVKPDEESSEDLMEIKQKLENTIGSEELQQKISQARTRASVSISDSTSIADKKSLNGSLHRKPSTDSQQSGSLVQSNNVKEINQ----NQYKTGEKLIETEKAETGSVKWTVYSHYLQSIGWFLAVSTIIMNAVFQSFSISANLWLSAWSSDNETVVNGTANTYKQNMYLGVYGAFGLGQAMTSFFCDLAPQLGCWLAARQMHNVMMRGVLRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPQQISDTIYCSYEVIATLVVISYSTPMFISVIVPIGLVYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQIIRAYGVQDRFVNESESRVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFSALFAVLDKDTMSAGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYSET-SQEAPWEIPDQDPPKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRALEHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLIQRTIREEFKDCT 1491 HSP 2 Score: 70.0922 bits (170), Expect = 2.930e-8 Identity = 69/268 (25.75%), Postives = 121/268 (45.15%), Query Frame = 0
Query: 146 VSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSV-------------NVVGQVAYVPQQAWMQNATVKNNI-LFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFA 395
V+++RI +Y + + + KD P V+ + + VL+ ++ + G +VG G+GKSSL A +E G + + ++ +PQ + + +++ N+ F K D ++ + E L ++ LP T E+ E G NLS GQ+Q + LARA V +LD+ +AVD I ++ I ++ + T + + H + + +D +IVL +G I E S L+ QK D A
Sbjct: 1270 VAVERIKEYSETSQEAPWEIPDQDPPKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRAL-EHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLI-QRTIREE--FKDCTVLTIAHRLNTILDSDRVIVLDKGSIIEFDSPDNLL-QKQDSA 1532
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|795109310|ref|XP_011882155.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X8 [Vollenhovia emeryi]) HSP 1 Score: 1199.5 bits (3102), Expect = 0.000e+0 Identity = 600/1037 (57.86%), Postives = 761/1037 (73.38%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWGKSE--PTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQT---LMEIKMELEDVLGEEKVKQEFERQQSRARTESICSVQSAFSNASSSNAII-------SQDNVDEV-----DEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWT---EGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELP-NKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+GLA+M+I IP N VI + + Q+ QMK+KD+RVKLM+E+L G+KVLKLY WE SF QIL IR KEI VLK+ A+L A +F+W PFLV+L SFT YV +D NVL+++ AFV+L+ NI+R P+S+LP MI +VQ VS+ RINK+MN EELD N ++HD + + V I NG F W E +L +I + +G L A+VGTVGSGKSSL+SA LGEM+K G VN G +AYV QQAW+QNAT+++N+LFGKA Y +IEACAL D ++LP GD TEIGEKGINLSGGQKQRV+LARA Y+D++ Y LDDPLSAVDSHVGKHIFEKVI G+L+ KTRVLVTH ITYLP+ D+IIVLK+G I+E G+Y+QL+ +KG FA+FL++++ E DE + L EIK +LE +G ++++Q+ Q R R S + ++ S N + SQ +V+ V E P +G LIE E ETGSV VY +Y+K+IGWF ++ M ++Q S+G++ WL+VW+ + + N+ + R++YLGVYG LGF QA +L LAI L +SK +H +L ++RSP+ FFDTTP GRI+NRF KDIDV DN LP NLR WL AS + T+++I PIF VI+P+ I++FIQ YV TSRQLKRLES+SRSPIYSHF ES+TGA IRA+G+++QFI+ESE +VD NQVCY+PSIIANRWLAVRLE +GN+I F AA+FA+L + SG VGL +SYAL +TQ LNWLVRMTSDVETNIVAVER+KEY T QEA W+ P N P ++WP+ G V+F+ + +RYR GLDLV+ + + GG+ +GIVGRTGAGKSSLT+A FR++E A G I ID ID+S+LGLHDLR +LTIIPQDPVLFSGTLR+NLDPF HSD+EVW ALE AHLK+F+A+L L H+VSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIR++F+ CT
Sbjct: 450 AGLAVMIILIPINGVIANKVKTLQIRQMKSKDERVKLMNEVLNGIKVLKLYAWEPSFEQQILKIRVKEIQVLKEAAYLNAGTSFIWSCAPFLVSLVSFTTYVLIDEKNVLNSKIAFVSLSLFNILRFPLSMLPMMIGNIVQAYVSVKRINKFMNMEELDPNNVQHDPSEPNALV-IENGSFCWDSEEIERPILRNINFHVEQGQLVAIVGTVGSGKSSLLSALLGEMDKLSGKVNTKGSIAYVSQQAWIQNATLQDNVLFGKAFNKSIYNRVIEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVALARAVYNDSENYFLDDPLSAVDSHVGKHIFEKVIGPNGLLKKKTRVLVTHSITYLPEVDNIIVLKDGEITECGTYKQLLEKKGAFAEFLVQHLQEVHVDEGSEADLREIKQQLESTMGADELQQKL--TQVRTRISESLSESGSVTDKKSLNGSLKRQYSTDSQQSVNYVHSNSTKEKEAPKPNNVGEKLIEVEKTETGSVKWKVYSHYLKSIGWFLSISTIVMNAVFQAFSIGSSVWLSVWSNDNQTIGNNTIDTARRDMYLGVYGALGFGQATFVVLSHATLAIGCLRSSKLLHSELLSAMLRSPLGFFDTTPSGRILNRFGKDIDVVDNVLPPNLRAWLLCLASVIATLVVISYSTPIFVVVILPIGAIYYFIQRFYVATSRQLKRLESVSRSPIYSHFSESVTGAQIIRAYGVQEQFIHESENRVDFNQVCYFPSIIANRWLAVRLEMVGNLIIFFAALFAVLGRDTMSSGLVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGET-PQEAPWKNPENTPPKEWPRHGRVDFKDFKVRYREGLDLVLHGLTFSVLGGEKIGIVGRTGAGKSSLTLAFFRIIEAAHGKILIDDIDISKLGLHDLRSRLTIIPQDPVLFSGTLRMNLDPFDCHSDEEVWRALEHAHLKSFIANLPSALLHEVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRQEFKECT 1482 HSP 2 Score: 77.7962 bits (190), Expect = 1.027e-10 Identity = 89/410 (21.71%), Postives = 176/410 (42.93%), Query Frame = 0
Query: 8 MVIAIPFNAVIVSFTRKY-----QLEQMKN--KDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVA---LSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSV-------------NVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQ 390
+V+ +P A+ R Y QL+++++ + SE + G ++++ YG ++ F+ + + V + + +II W++V + + F + G + + + ++++Y + ++ L M + V+++RI +Y + + K+ P V + + + VLH +T + G +VG G+GKSSL AF +E G + ++ ++ +PQ + + T++ N+ D+ +E L S + LP E+ E G NLS GQ+Q + LARA V +LD+ +AVD I + I ++ + T + + H + + +D +IVL +G I E S + L+
Sbjct: 1118 VVVILPIGAIYYFIQRFYVATSRQLKRLESVSRSPIYSHFSESVTGAQIIRAYGVQEQFIHE-----SENRVDFNQVCYFPSIIANRWLAVRLEMVGNLIIFFAALFAVLGRDTMSSGLVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGETPQEAPWKNPENTPPKEWPRHGRVDFKDFKVRYREGLDLVLHGLTFSVLGGEKIGIVGRTGAGKSSLTLAFFRIIEAAHGKILIDDIDISKLGLHDLRSRLTIIPQDPVLFSGTLRMNLDPFDCHSDEEVWRALEHAHLKSFIANLPSALLHEVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLI-QTTIRQE--FKECTVLTIAHRLNTILDSDRVIVLDKGLIVEYDSPEVLLRN 1519
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|936574288|ref|XP_014219240.1| (multidrug resistance-associated protein 1 isoform X5 [Copidosoma floridanum]) HSP 1 Score: 1198.73 bits (3100), Expect = 0.000e+0 Identity = 580/1038 (55.88%), Postives = 770/1038 (74.18%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWGKS--EPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQT---LMEIKMELEDVLGEEKVKQEFERQQSRAR-----TESICSVQS--------AFSNASSSNAIISQDNVDEVDEPLEPSATKIGTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWT---EGVFGNSSEPQYRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELPNK-PEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
SGLA+M+I IP NA++ R Q++QMKNKDDRVKLM+E+L G+KVLKLY WE SF QIL IR+KEI VLK+ A++ A +F+W PF+V+L SF +V +D NVLD++ AFV+L+ NI+R P+S+LP M+ +VQ VS+ RINK+MN+EELD N ++H E + P+ I NG F+W E +L +I L+I +G L A+VG+VGSGKSSLISA LGEMEK G VN G++AYV QQAW+QNAT+++NILFG Y ++EACAL D ++LP GD TEIGEKGINLSGGQKQRVSLARA Y++AD+Y LDDPLSAVDSHVGKHIFE +I +G+++ KTR+LVTHGITYLP+ DHIIVLK+G ISE G+Y++L+ ++G FADFL++++ E DE++ LMEIK +LE+ +G E+++Q+ + ++RA + SI +S +++ S +++ +NV E+++ + K G LIE E AETGSV +VY +Y+++IGWF V+ M ++Q S+ N WL+ W+ E V ++ +N+YLGVYG G QA ++ + + A++QMH M+ V+R+P++FFDTTP+GRI++RFAKD+DV D +LP + + + T+++I P+F SVIVP+ ++++FIQ YV TSRQLKRLES+SRSPIYSHFGES+TGA IRA+G++ +F+NESE +VD NQVCYYPSIIANRWLAVRLE +GN+I F +A+FA+L+ + +G VGL ISYAL +TQ LNWLVRMTSDVETNIVAVER+KEY+ T QEA WE+P++ P +DWP G VEF Y +RYR GLDLV+ + + GG+ +GIVGRTGAGKSSLT+ALFR++E A G I ID +D+S+LGLH LR +LTIIPQDPVLFSG+LR+NLDPF SD ++W ALE AHLK FV L + L+H+V+EGG+NLSVGQRQL+CLARALLRKTKVLILDEATAAVDLETDDLIQ TIR++F+ CT
Sbjct: 450 SGLAVMIILIPVNALLAGKVRNLQIKQMKNKDDRVKLMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVSLVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQH-ETSEVNPIVIENGNFAWDSEHIEKPMLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKGKIAYVSQQAWIQNATLQDNILFGSPFNKALYHRVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSRGLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVKPDEESSEDLMEIKQKLENTIGSEELQQKISQARTRASVSISDSTSIADKKSLNGSLHRKPSTDSQQSGSLVQSNNVKEINQ----NQYKTGEKLIETEKAETGSVKWTVYSHYLQSIGWFLAVSTIIMNAVFQSFSISANLWLSAWSSDNETVVNGTANTYKQNMYLGVYGAFGLGQAMTSFFCDLAPQLGCWLAARQMHNVMMRGVLRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPQQISDTIYCSYEVIATLVVISYSTPMFISVIVPIGLVYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQIIRAYGVQDRFVNESESRVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFSALFAVLDKDTMSAGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYSET-SQEAPWEIPDQDPPKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRALEHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLIQRTIREEFKDCT 1481 HSP 2 Score: 69.707 bits (169), Expect = 3.131e-8 Identity = 69/268 (25.75%), Postives = 121/268 (45.15%), Query Frame = 0
Query: 146 VSLDRINKYMNNEELDDNALEHDEKQKDTP----VKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSV-------------NVVGQVAYVPQQAWMQNATVKNNI-LFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFA 395
V+++RI +Y + + + KD P V+ + + VL+ ++ + G +VG G+GKSSL A +E G + + ++ +PQ + + +++ N+ F K D ++ + E L ++ LP T E+ E G NLS GQ+Q + LARA V +LD+ +AVD I ++ I ++ + T + + H + + +D +IVL +G I E S L+ QK D A
Sbjct: 1260 VAVERIKEYSETSQEAPWEIPDQDPPKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRAL-EHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLI-QRTIREE--FKDCTVLTIAHRLNTILDSDRVIVLDKGSIIEFDSPDNLL-QKQDSA 1522
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|1227956547|ref|XP_021917192.1| (multidrug resistance-associated protein 1 isoform X6 [Zootermopsis nevadensis]) HSP 1 Score: 1197.96 bits (3098), Expect = 0.000e+0 Identity = 606/1041 (58.21%), Postives = 770/1041 (73.97%), Query Frame = 0
Query: 3 SGLAIMVIAIPFNAVIVSFTRKYQLEQMKNKDDRVKLMSEILGGVKVLKLYGWEQSFMGQILDIRDKEIVVLKKTAWLGAIINFVWISVPFLVALSSFTVYVFMDGGNVLDAQKAFVTLTYLNIMRMPMSVLPFMIIGLVQVGVSLDRINKYMNNEELDDNALEHDEKQKDTPVKITNGIFSWGKSEPTVLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVGQVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQKGDFADFLLEYMSEETEDEQT----LMEIKMELEDVLGEEKVKQEFERQQSRA-------------RTESICSVQSAFSNASSSNAIISQDNVDEVDEPLEPSATKI----GTNLIEKEIAETGSVGLSVYGYYMKNIGWFGVVAGFAMQLIYQISSVGTNYWLNVWT--EGVFGNSSEPQ-YRNLYLGVYGGLGFCQAFSTMLLSIVLAISTLNASKQMHKTMLHRVMRSPMSFFDTTPLGRIVNRFAKDIDVCDNTLPNNLRQWLNTFASFLGTIILIITVIPIFASVIVPVAIIFFFIQSIYVNTSRQLKRLESISRSPIYSHFGESITGASTIRAFGLEKQFINESEQKVDINQVCYYPSIIANRWLAVRLETIGNIITFAAAIFAILNPSGIDSGEVGLIISYALNVTQVLNWLVRMTSDVETNIVAVERVKEYTLTLEQEAEWELP-NKPEEDWPQSGEVEFQKYGMRYRPGLDLVVKDIDCHIQGGQSVGIVGRTGAGKSSLTVALFRLVEPAEGTIQIDGIDVSQLGLHDLRKKLTIIPQDPVLFSGTLRINLDPFGIHSDKEVWTALELAHLKTFVASLEDGLSHQVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRKQFQGCT 1018
+GLA+M+I IP NAVI + + Q+ QMK+KD+RVKLM+E+L G+KVLKLY WE SF QIL IR+KEI VLK+ A+L A +F+W PFLV+L+S YV +D +VLDA+KAFV+L+ NI+RMP+SV+PF+II LVQ VS+ R+N++MN+EELD N+++HD+ +K+ V I NG FSWG + +L +I L +GSL AVVGTVGSGKSSLISAFLGEM+K G VN G +AYVPQQAW+QNAT+ NNI+FGK+ YQ IIEACAL DLE+LP D TEIGEKGINLSGGQKQRVSLARA Y++AD+Y LDDPLSAVDSHVGKHIFE VI GIL KTRVLVTHGITYLP D I+VLK+G ++E G+Y+QL+ +KG FA+FL++++ E D+ T L EIK +LE+ +G E+++Q+ +SRA + S+ S SS+ S+ ++ +D+ ++ + G LIE E ETGSV VY YY+K+IG F A L++Q S+G+N WL+ W+ + V+ N + + R+LYLGVYG LG QAF++ + I A++ +H ML ++R+P+ FFDTTP GRI+ RFAKD+DV D T+P + + + T+++I PIF SVI+P+ II++FIQ YV+TSRQLKRLES+SRSP+YSHFGESITGA TIRA+ ++++FI ESE++VD NQVCYYPSIIANRWLAVRLE +GN+I F A++FA+LN + G VGL +SYAL +TQ LNWLVRMTSDVETNIVAVER+KEY T EQEA W++P N+P WP+ G+VEF+ Y +RYR GLDLV++ I ++GG+ VGIVGRTGAGKSSLT+ LFR++E A G I IDG+DVS+LGLH LR +LTIIPQDPVLFSGTLR+NLDPFG SD ++W ALE AHLK FV +L D L H VSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIR +F+ T
Sbjct: 452 AGLAVMIILIPVNAVIANRVKTLQIRQMKSKDERVKLMNEVLSGIKVLKLYAWEPSFEQQILKIREKEIAVLKQAAYLNASTSFIWSCAPFLVSLASLATYVLVDPSHVLDAEKAFVSLSLFNIIRMPISVIPFLIITLVQASVSIKRVNRFMNSEELDPNSVQHDQSEKNHLV-IENGNFSWGSEDQVILRNINLSFKQGSLVAVVGTVGSGKSSLISAFLGEMDKITGRVNTKGSIAYVPQQAWIQNATLLNNIIFGKSLDHSSYQRIIEACALKPDLEMLPASDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENVIGPSGILRRKTRVLVTHGITYLPDVDMIVVLKDGEVTEMGTYKQLLEKKGAFAEFLVQHLQEIGVDDGTSEADLDEIKQQLENTIGTEELQQKLNHARSRASESQSDSASLSGEKQSLTGSLNRQHSVESSTERGGSRHRLNSLDKDTGSNSKFVAKPNGDKLIEAEKTETGSVKWHVYTYYLKSIGIFLSGATIFFNLVFQAFSIGSNVWLSEWSNDKNVYVNETVNEGKRDLYLGVYGALGAGQAFASFFCDLAPQIGCWTAARVLHIVMLRGILRAPLMFFDTTPSGRIIGRFAKDVDVVDTTIPQQISDLVYCLFEVVATLVVISYSTPIFISVIIPIGIIYYFIQRFYVSTSRQLKRLESVSRSPVYSHFGESITGAQTIRAYNVQQRFIRESEERVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFASLFAVLNRDTMSPGLVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGET-EQEAPWDIPTNQPSSAWPEKGQVEFKDYQVRYREGLDLVLRGISFTVKGGEKVGIVGRTGAGKSSLTLGLFRIIEAAGGKILIDGVDVSKLGLHALRSRLTIIPQDPVLFSGTLRVNLDPFGSCSDSDIWLALEHAHLKAFVKALPDSLEHSVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRSEFKDST 1490 HSP 2 Score: 66.6254 bits (161), Expect = 2.787e-7 Identity = 54/213 (25.35%), Postives = 93/213 (43.66%), Query Frame = 0
Query: 192 VLHDITLEIPKGSLTAVVGTVGSGKSSLISAFLGEMEKEQGSVNVVG-------------QVAYVPQQAWMQNATVKNNILFGKAPKDKRYQEIIEACALVSDLEILPGGDTTEIGEKGINLSGGQKQRVSLARACYSDADVYLLDDPLSAVDSHVGKHIFEKVISKKGILEGKTRVLVTHGITYLPKTDHIIVLKEGRISEQGSYQQLVHQK 391
VL I+ + G +VG G+GKSSL +E G + + G ++ +PQ + + T++ N+ + D +E L + ++ LP + E G NLS GQ+Q + LARA V +LD+ +AVD I + S+ + T + + H + + +D +IVL G + E + + L+ K
Sbjct: 1319 VLRGISFTVKGGEKVGIVGRTGAGKSSLTLGLFRIIEAAGGKILIDGVDVSKLGLHALRSRLTIIPQDPVLFSGTLRVNLDPFGSCSDSDIWLALEHAHLKAFVKALPDSLEHSVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRSE---FKDSTVLTIAHRLNTIMDSDRVIVLDRGLLVEYDTPEALLQNK 1528 The following BLAST results are available for this feature:
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 17
Pagesback to top
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
Pagesback to top
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold2698_size13172:6..3686- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold2698_size13172-snap-gene-0.3 ID=maker-scaffold2698_size13172-snap-gene-0.3|Name=multidrug resistance-associated protein 1 isoform x4|organism=Tigriopus kingsejongensis|type=gene|length=3681bp|location=Sequence derived from alignment at scaffold2698_size13172:6..3686- (Tigriopus kingsejongensis)back to top Synonyms
The feature 'multidrug resistance-associated protein 1 isoform x4' has the following synonyms
Add to Basket
|