BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. L. salmonis genes
Match: EMLSAG00000000339 (supercontig:LSalAtl2s:LSalAtl2s104:636256:638695:-1 gene:EMLSAG00000000339 transcript:EMLSAT00000000339 description:"maker-LSalAtl2s104-augustus-gene-6.22")

HSP 1 Score: 498.819 bits (1283), Expect = 1.230e-168
Identity = 271/541 (50.09%), Postives = 352/541 (65.06%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAM---YSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGK-SNTNGPTTQNSI--PMSQPLGLMPSSRISPGRSVKDPSEE--PNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLNDKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
            MA+ E++ +MV +FR+SELQ LMA+AGKSKSGRKS+LQ RAL+L+ +NS +IK+KIREL++ M      +G+    +P +        RS    S  P  +A      T  G    RTR S A       S V   S  +  + S+      S+      +    TDS   L+     SP+ + +   +    I     RG  SNT   T  +S+   +     L+P ++        +P  +   N HLMYP  PDV+L  LPF+KV A L++P +L P  +ARFQ Q   FHL+PSQA+ IA S +RD+ G++EYK QIQMRF L ETSC QDDNFPASICV VN + Q LPN IPTNKPGVEPKRPPKPINIT+ CKLS+T+ NYL+V+W VE G+GF V+IYYV+KL+S  L+K LK++G RH  YT+A+IK+KLND+D ++ TTSCKVTLACPLGKMRMS PCRA+TCDHLQCFDA L++ MNERKPKW+CPVCNK A+++NL +DG+F EVL   KL   ++E+VL ND  WE L
Sbjct:    1 MADLEMVQAMVMNFRLSELQALMAYAGKSKSGRKSDLQIRALNLIRLNSNDIKMKIRELNNEMPRPGIGIGNNNKESPLNQLLGERSTRSRKGESDNPSSNALEEAPVTRRGARSTRTRVSYAEPDEDETSEVLSDSSXDESEESDKGYNPPSEEEEVVESGGEDTDSAIPLSPSH--SPTRLHSKKSANLPNILKKSPRGHISNTGSKTIISSLLPTIKTADILVPHTKTVVPIQNSEPKYDIANNGHLMYPPCPDVQLVSLPFYKVEAILLKPSSLNPSDSARFQVQTFVFHLTPSQANAIAGSGYRDATGKLEYKNQIQMRFCLNETSCPQDDNFPASICVIVNGRSQALPNIIPTNKPGVEPKRPPKPINITSNCKLSATLPNYLNVTWTVEAGKGFCVAIYYVEKLTSNTLIKILKDKGNRHSAYTKAIIKDKLNDRDCEIATTSCKVTLACPLGKMRMSLPCRATTCDHLQCFDARLYIQMNERKPKWICPVCNKNAMYENLMVDGYFFEVLNDPKL-GTENEIVLKNDAEWEAL 538          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. L. salmonis genes
Match: EMLSAG00000009591 (supercontig:LSalAtl2s:LSalAtl2s617:113952:116969:-1 gene:EMLSAG00000009591 transcript:EMLSAT00000009591 description:"maker-LSalAtl2s617-augustus-gene-1.39")

HSP 1 Score: 312.383 bits (799), Expect = 5.920e-98
Identity = 150/301 (49.83%), Postives = 206/301 (68.44%), Query Frame = 0

Query:  291 PTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFS--LLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLNDKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKEGVSSS 589
            P  PDVKL +LPF+ V+A L+ P +L      R QE +  F ++PSQA++IAS        +++Y  QIQ+RF    L++S E  D FP  I ++VN K   LPNPIPTN+ GVEPKRPPKP+NIT+ CKLS  + N +++ WA E G+ + V I+ V K +S DL++ LK++G R+ +YT+  I  K+ D D DV T   +V++ACPLGKMRM  PCR STC HLQCFDA+LFL MNERKP W CPVC+  ALFD+L IDG+F +V+ S  LP  +++++L+ DGSW P+P ++E   +S
Sbjct:  201 PLQPDVKLVKLPFYDVIAELLXPSSLVTQGNNRHQEAQFQFFMTPSQATDIASHRDIRISSKLDYLYQIQLRFCPLSLDSSKEMADEFPPGIILQVNGKGVVLPNPIPTNRTGVEPKRPPKPVNITSCCKLSPILPNVVNIKWAGEYGKWWVVGIWLVMKCTSEDLLERLKKKGTRNSEYTKKTIIAKMCDDD-DVETECLRVSVACPLGKMRMXLPCRPSTCGHLQCFDASLFLQMNERKPTWNCPVCDSKALFDDLMIDGYFMDVINSQDLPKDENDIILNGDGSWMPVPKEEESAKTS 500          

HSP 2 Score: 70.8626 bits (172), Expect = 5.291e-13
Identity = 36/73 (49.32%), Postives = 51/73 (69.86%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASV 119
            + E E L  M+ +FR+SELQ L+ FAG++K+G+K ELQ RAL+LV + S+ ++ KIREL  A  S    AAS+
Sbjct:    4 LQEQESLKHMILTFRVSELQXLLGFAGRNKNGKKHELQGRALELVKIRSSPMQAKIRELYKA--SQAQQAASI 74          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|56404326|sp|Q6AZ28.1|PIAS2_RAT (RecName: Full=E3 SUMO-protein ligase PIAS2; AltName: Full=Androgen receptor-interacting protein 3; Short=ARIP3; AltName: Full=DAB2-interacting protein; Short=DIP; AltName: Full=E3 SUMO-protein transferase PIAS2; AltName: Full=Msx-interacting-zinc finger protein; AltName: Full=Protein inhibitor of activated STAT x; AltName: Full=Protein inhibitor of activated STAT2)

HSP 1 Score: 312.383 bits (799), Expect = 1.519e-96
Identity = 169/401 (42.14%), Postives = 238/401 (59.35%), Query Frame = 0

Query:  295 DVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSL--GRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKEGVSSSDREPTPPPSAKIEKVETLNVEDDEVPIPIPPPAVNNGHSDLGSLP-GVSPKTKNDKRSFDCITLDSDSDDEGPETRPPNRKRATAGETSSVPSRPTYTAPPGS 691
            DV+L+ LPF+ V+  L++P +L   S  RFQE+   F L+P Q  EI  S  RD L  GR +Y  Q+Q+R  L ETSC Q+DN+P S+C+KVN K+ PLP   P  K G+E KRP +P+NIT+L +LSS + N + +SWA EIG+ +++S+Y V +L+S  L++ LK +GIR+PD++RA+IKEKL  D D ++ TTS +V+L CPLGKMR++ PCRA TC HLQCFDA L+L MNE+KP W+CPVC+K A +++L +DG F E+L      +   E+    DGSW P+  KKE +  + +     P  K+E                         S + S P  V+  +   K+  D I L  +S  +  E  P  RK     ET S P++      P S
Sbjct:  145 DVQLKTLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICIS--RDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVTSQ-----PCTKVES------------------------SSVFSKPCSVTVASDASKKKIDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSS 511          

HSP 2 Score: 62.7734 bits (151), Expect = 5.123e-9
Identity = 33/65 (50.77%), Postives = 44/65 (67.69%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSA-EIKLKIRELSHAMY 110
            MA+ E L +MV SFR+SELQ L+ FAG++KSGRK +L  RAL L+       +++KIREL    Y
Sbjct:    1 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCTPAVQIKIRELYRRRY 65          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|229463031|sp|O75928.3|PIAS2_HUMAN (RecName: Full=E3 SUMO-protein ligase PIAS2; AltName: Full=Androgen receptor-interacting protein 3; Short=ARIP3; AltName: Full=DAB2-interacting protein; Short=DIP; AltName: Full=E3 SUMO-protein transferase PIAS2; AltName: Full=Msx-interacting zinc finger protein; Short=Miz1; AltName: Full=PIAS-NY protein; AltName: Full=Protein inhibitor of activated STAT x; AltName: Full=Protein inhibitor of activated STAT2)

HSP 1 Score: 313.923 bits (803), Expect = 1.547e-96
Identity = 170/400 (42.50%), Postives = 237/400 (59.25%), Query Frame = 0

Query:  295 DVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSL--GRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKEGVSSSDREPTPPPSAKIEKVETLNVEDDEVPIPIPPPAVNNGHSDLGSLPGVSPKTKNDKRSFDCITLDSDSDDEGPETRPPNRKRATAGETSSVPSRPTYTAPPGS 691
            DV+L+ LPF+ V+  L++P +L   S  RFQE+   F L+P Q  EI  S  RD L  GR +Y  Q+Q+R  L ETSC Q+DN+P S+C+KVN K+ PLP   P  K G+E KRP +P+NIT+L +LSS + N + +SWA EIG+ +++S+Y V +L+S  L++ LK +GIR+PD++RA+IKEKL  D D ++ TTS +V+L CPLGKMR++ PCRA TC HLQCFDA L+L MNE+KP W+CPVC+K A +++L +DG F E+L      +   E+    DGSW P+  KKE +  S +     P  KIE                         S L     V+  ++  K+  D I L  +S  +  E  P  RK     ET S P++      P S
Sbjct:  145 DVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICIS--RDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVSSQ-----PCTKIE-----------------------SSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSS 511          

HSP 2 Score: 63.5438 bits (153), Expect = 2.996e-9
Identity = 34/65 (52.31%), Postives = 45/65 (69.23%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVN-SAEIKLKIRELSHAMY 110
            MA+ E L +MV SFR+SELQ L+ FAG++KSGRK +L  RAL L+    S  +++KIREL    Y
Sbjct:    1 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRY 65          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|56405305|sp|O88907.2|PIAS1_MOUSE (RecName: Full=E3 SUMO-protein ligase PIAS1; AltName: Full=DEAD/H box-binding protein 1; AltName: Full=Protein inhibitor of activated STAT protein 1; AltName: Full=RING-type E3 ubiquitin transferase PIAS1)

HSP 1 Score: 313.153 bits (801), Expect = 5.056e-96
Identity = 157/336 (46.73%), Postives = 226/336 (67.26%), Query Frame = 0

Query:  253 TQNSIPMSQPLGLMPSSRISPGRSVKDPSEEPNSHL---MYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKE 584
            T +  P S PL  +P S + P   ++ P      HL   ++P  PD+KL++LPF+ ++  L++P +L   ++ RF+E   +F L+P Q  +I SSS   S  + ++  Q+Q+RF L ETSC Q+D+FP ++CVKVN K   LP  +P  K GVEPKRP +PINIT+L +LS+T+ N + VSW  EIGR +++++Y V +LSS  L++ L+ +GIR+PD++RA+IKEKL  D D ++ TTS +V+L CPLGKMR++ PCRA TC HLQCFDA L++ MNE+KP W+CPVC+K A +++L IDG F E+LK         E+    DGSW P+  KKE
Sbjct:   98 TYDGHPASSPL--LPVSLLGPKHELELP------HLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQI-SSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGSWAPMRSKKE 421          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|20138891|sp|O75925.2|PIAS1_HUMAN (RecName: Full=E3 SUMO-protein ligase PIAS1; AltName: Full=DEAD/H box-binding protein 1; AltName: Full=E3 SUMO-protein transferase PIAS1; AltName: Full=Gu-binding protein; Short=GBP; AltName: Full=Protein inhibitor of activated STAT protein 1; AltName: Full=RNA helicase II-binding protein)

HSP 1 Score: 312.383 bits (799), Expect = 1.078e-95
Identity = 156/336 (46.43%), Postives = 226/336 (67.26%), Query Frame = 0

Query:  253 TQNSIPMSQPLGLMPSSRISPGRSVKDPSEEPNSHL---MYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKE 584
            T +  P S PL  +P S + P   ++ P      HL   ++P  PD+KL++LPF+ ++  L++P +L   ++ RF+E   +F L+P Q  +I SSS   S  + ++  Q+Q+RF L ETSC Q+D+FP ++CVKVN K   LP  +P  K GVEPKRP +PINIT+L +LS+T+ N + VSW  EIGR +++++Y V +LSS  L++ L+ +GIR+PD++RA+IKEKL  D D ++ TTS +V+L CPLGKMR++ PCRA TC HLQCFDA L++ MNE+KP W+CPVC+K A +++L IDG F E+LK         E+    DG+W P+  KKE
Sbjct:   98 TYDGHPASSPL--LPVSLLGPKHELELP------HLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQI-SSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGTWAPMRSKKE 421          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|56404605|sp|Q8C5D8.2|PIAS2_MOUSE (RecName: Full=E3 SUMO-protein ligase PIAS2; AltName: Full=Androgen receptor-interacting protein 3; Short=ARIP3; AltName: Full=DAB2-interacting protein; Short=DIP; AltName: Full=Msx-interacting zinc finger protein; AltName: Full=Protein inhibitor of activated STAT x; AltName: Full=Protein inhibitor of activated STAT2; AltName: Full=RING-type E3 ubiquitin transferase PIAS2)

HSP 1 Score: 310.842 bits (795), Expect = 2.025e-95
Identity = 169/401 (42.14%), Postives = 238/401 (59.35%), Query Frame = 0

Query:  295 DVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSL--GRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKEGVSSSDREPTPPPSAKIEKVETLNVEDDEVPIPIPPPAVNNGHSDLGSLP-GVSPKTKNDKRSFDCITLDSDSDDEGPETRPPNRKRATAGETSSVPSRPTYTAPPGS 691
            DV+L+ LPF+ V+  L++P +L   S  RFQE+   F L+P Q  EI  S  RD L  GR +Y  Q+Q+R  L ETSC Q+DN+P S+C+KVN K+ PLP   P  K G+E KRP +P+NIT+L +LSS + N + +SWA EIG+ +++S+Y V +L+S  L++ LK +GIR+PD++RA+IKEKL  D D ++ TTS +V+L CPLGKMR++ PCRA TC HLQCFDA L+L MNE+KP W+CPVC+K A +++L +DG F E+L      +   E+    DGSW P+  KKE +  + +     P  K+E                         S + S P  V+  +   K+  D I L  +S  +  E  P  RK     ET S P++      P S
Sbjct:  145 DVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICIS--RDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVTSQ-----PCTKVES------------------------SSVFSKPCSVTVASDASKKKIDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSS 511          

HSP 2 Score: 63.929 bits (154), Expect = 2.748e-9
Identity = 34/65 (52.31%), Postives = 45/65 (69.23%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVN-SAEIKLKIRELSHAMY 110
            MA+ E L +MV SFR+SELQ L+ FAG++KSGRK +L  RAL L+    S  +++KIREL    Y
Sbjct:    1 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRY 65          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|56405302|sp|O54714.3|PIAS3_MOUSE (RecName: Full=E3 SUMO-protein ligase PIAS3; AltName: Full=E3 SUMO-protein transferase PIAS3; AltName: Full=Protein inhibitor of activated STAT protein 3)

HSP 1 Score: 310.842 bits (795), Expect = 2.135e-95
Identity = 170/425 (40.00%), Postives = 254/425 (59.76%), Query Frame = 0

Query:  262 PLGLMPSSRISPGRSVKDPSEEPNSH--LMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKEGVSSSDREPTPPPSAKIEKVETLNVEDDEVPIPIPPPAVNNGHSDLGSLPGVSPKTKNDKRSFDCITLDSDSDDEGPETRPPNRKRATAGETSSVPSRP 683
            PL  +P + ++PG ++  P  E + H  L  P  PDV ++ LPF++V   L++P  L   S+ RF+E   +F L+P Q  +I +S       + +Y  Q+Q+RF L ETSC Q+D FP ++ VKVN K+ PLP  +P  K G EPKRP +PINIT L +LS+T+ N + V+W+ E GR +++S+Y V +L++  L++ L+ +GIR+PD++RA+IKEKL  D D +V TTS +V+L CPLGKMR++ PCRA TC HLQ FDA L+L MNE+KP W CPVC+K A +++L IDG F E+L S    +   E+    DGSW P+  KKE       E  PPP   ++ ++   V++                       G+ P++K      D +T++S SD+   E  PP +K      ++++P+ P
Sbjct:   92 PLAPIPPTLLTPG-TLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSC---SDCDEIQFMEDGSWCPMKPKKEA-----SEVCPPPGYGLDGLQYSAVQE-----------------------GIQPESKKRVEVID-LTIESSSDE---EDLPPTKKHCPV-TSAAIPALP 479          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|56405390|sp|Q9Y6X2.2|PIAS3_HUMAN (RecName: Full=E3 SUMO-protein ligase PIAS3; AltName: Full=E3 SUMO-protein transferase PIAS3; AltName: Full=Protein inhibitor of activated STAT protein 3)

HSP 1 Score: 306.99 bits (785), Expect = 7.979e-94
Identity = 169/425 (39.76%), Postives = 250/425 (58.82%), Query Frame = 0

Query:  262 PLGLMPSSRISPGRSVKDPSEEPNSH--LMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKEGVSSSDREPTPPPSAKIEKVETLNVEDDEVPIPIPPPAVNNGHSDLGSLPGVSPKTKNDKRSFDCITLDSDSDDEGPETRPPNRKRATAGETSSVPSRP 683
            PL  +P + ++PG ++  P  E + H  L  P  PDV ++ LPF++V   L++P  L   S+ RF+E   +F L+P Q  +I +S       + +Y  Q+Q+RF L ETSC Q+D FP ++ VKVN K+ PLP  +P  K G EPKRP +PINIT L +LS+T+ N + V+W+ E GR +++S+Y V +L++  L++ L+ +GIR+PD++RA+IKEKL  D D +V TTS +V+L CPLGKMR++ PCRA TC HLQ FDA L+L MNE+KP W CPVC+K A +++L IDG F E+L S    +   E+    DGSW P+  KKE       E  PPP   ++ ++   V+                        G  P     K     +T++S SD+   E  PP +K  +   ++++P+ P
Sbjct:   92 PLAPIPPTLLAPG-TLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSC---SDCDEIQFMEDGSWCPMKPKKEA-----SEVCPPPGYGLDGLQYSPVQ------------------------GGDPSENKKKVEVIDLTIESSSDE---EDLPPTKKHCSV-TSAAIPALP 479          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|56404322|sp|O70260.2|PIAS3_RAT (RecName: Full=E3 SUMO-protein ligase PIAS3; AltName: Full=E3 SUMO-protein transferase PIAS3; AltName: Full=KChAP; AltName: Full=Potassium channel-associated protein; AltName: Full=Protein inhibitor of activated STAT protein 3)

HSP 1 Score: 306.22 bits (783), Expect = 1.438e-93
Identity = 156/353 (44.19%), Postives = 227/353 (64.31%), Query Frame = 0

Query:  262 PLGLMPSSRISPGRSVKDPSEEPNSH--LMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKEGVSSSDREPTPPPSAKIEKVETLNVED 611
            PL  +P + ++PG ++  P  E + H  L  P  PDV ++ LPF++V   L++P  L   S+ RF+E   +F L+P Q  +I +S       + +Y  Q+Q+RF L ETSC Q+D FP ++ VKVN K+ PLP  +P  K G EPKRP +PINIT L +LS+T+ N + V+W+ E GR +++S+Y V +L++  L++ L+ +GIR+PD++RA+IKEKL  D D +V TTS +V+L CPLGKMR++ PCRA TC HLQ FDA L+L MNE+KP W CPVC+K A +++L IDG F E+L S    +   E+    DGSW P+  KKE       E  PPP   ++ ++   V++
Sbjct:   92 PLASIPPTLLTPG-TLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSC---SDCDEIQFMEDGSWCPMKPKKEA-----SEVCPPPGYGLDGLQYSPVQE 435          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|34922847|sp|Q9JM05.2|PIAS4_MOUSE (RecName: Full=E3 SUMO-protein ligase PIAS4; AltName: Full=PIASy; AltName: Full=Protein inhibitor of activated STAT protein 4; AltName: Full=Protein inhibitor of activated STAT protein gamma; Short=PIAS-gamma; AltName: Full=RING-type E3 ubiquitin transferase PIAS4)

HSP 1 Score: 249.21 bits (635), Expect = 2.050e-73
Identity = 127/293 (43.34%), Postives = 185/293 (63.14%), Query Frame = 0

Query:  294 PDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASS-SFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKE 584
            P+V+L +LPFF ++  L++P  L P S  + QE    F L+P Q   I +S   +  +  V    Q+ +R    +TSC Q+D +P +I VKVN+    +P   P+NKPGVEPKRP +PIN+T L  LSS   N + V+W    G+ ++V++Y V +L+S DL++ LK  G++HP+  +A++KEKL  D D ++ TT  +V+L CPL KMR+S PCRA TC HLQCFDA  +L MNE+KP W+CPVC+K A +D L IDG  +++L   +      E+    +GSW P+  +KE
Sbjct:  122 PEVRLVKLPFFNMLDELLKPTELVPQSAEKLQESPCIFALTPRQVEMIRNSRELQPGVKAV----QVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSA-TNRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSECE---GADEIEFLAEGSWRPIRAEKE 405          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. SwissProt
Match: gi|34922831|sp|Q8N2W9.1|PIAS4_HUMAN (RecName: Full=E3 SUMO-protein ligase PIAS4; AltName: Full=PIASy; AltName: Full=Protein inhibitor of activated STAT protein 4; AltName: Full=Protein inhibitor of activated STAT protein gamma; Short=PIAS-gamma; AltName: Full=RING-type E3 ubiquitin transferase PIAS4)

HSP 1 Score: 244.202 bits (622), Expect = 1.765e-71
Identity = 126/293 (43.00%), Postives = 185/293 (63.14%), Query Frame = 0

Query:  294 PDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASS-SFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKE 584
            P+V+L +LPFF ++  L++P  L P +  + QE    F L+P Q   I +S   +  +  V    Q+ +R    +TSC Q+D +P +I VKVN+    +P   P+NKPGVEPKRP +PIN+T L  LSS   N + V+W    G+ ++V++Y V +L+S +L++ LK  G++HP+  +A++KEKL  D D ++ TT  +V+L CPL KMR+S PCRA TC HLQCFDA  +L MNE+KP W+CPVC+K A +D L IDG  +++L   +      E+    DGSW P+  +KE
Sbjct:  129 PEVRLVKLPFFNMLDELLKPTELVPQNNEKLQESPCIFALTPRQVELIRNSRELQPGVKAV----QVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSA-TNRITVTWG-NYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAPYDQLIIDGLLSKILSECE---DADEIEYLVDGSWCPIRAEKE 412          

HSP 2 Score: 57.3806 bits (137), Expect = 2.837e-7
Identity = 32/69 (46.38%), Postives = 43/69 (62.32%), Query Frame = 0

Query:   55 SMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVN-SAEIKLKIRELSHAMYSSLGSAASVNPY 122
            +MV SFR+S+LQ L+ F G+SKSG K EL  RAL LV  + S E+  KI+EL    Y+   S  +  P+
Sbjct:   10 NMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKNSEPAPQPH 78          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|766928346|ref|XP_011496212.1| (PREDICTED: E3 SUMO-protein ligase PIAS2 [Ceratosolen solmsi marchali])

HSP 1 Score: 437.187 bits (1123), Expect = 4.226e-142
Identity = 242/534 (45.32%), Postives = 327/534 (61.24%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSIPMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
            M+E++ L +MV SFR+SELQ L+ FAG++KSGRK+ELQARAL+L+ + S  ++LKIREL   + +   +A  +           G+S G + Q+ ER+    N  T  GH       S    + +++S   D+ PA      + +    SQ +  S  SV Q     S+   +R++ + +  +  +FA                   Q  IP+  PL + P+                     YP  PDVKL++LPFF ++  L++P +L P  T R QE    FHL+P Q+++IASS       +++Y  Q+QMRF L ETSCEQ+D FP SI VKVN K+ PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+ N + VSW+ + GR + +++Y V KL+S +L+  LK RG++H DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCRASTC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F EVL S KL    +E+ L  DGSWE L
Sbjct:    1 MSETDELENMVLSFRVSELQMLLGFAGRNKSGRKNELQARALELLRLRSHPVQLKIRELYKTIQADQLAAHQM----------YGQSEGVSEQQIERNLLSRNYFTRQGHA---QAMSQQQQSQQSVSATKDLPPA------HQASIPQSQVAQRST-SVYQNPGYTSVTPQTRST-NALYPNYAAFA------------------QQKVIPIPTPLQIQPNQ--------------------YPVHPDVKLKKLPFFDLLGELLKPSSLMPQGTMRLQENSFVFHLTPQQSTDIASSRDCRQGSKMDYTVQVQMRFCLQETSCEQEDYFPPSINVKVNGKLCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVGNQITVSWSADYGRRYAIAVYLVRKLTSSELLTRLKNRGVKHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRASTCSHLQCFDASLFLQMNERKPTWNCPVCDKSALYDNLTIDGYFQEVLNSTKLLPDVNEIQLLQDGSWENL 475          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|936572260|ref|XP_014218500.1| (E3 SUMO-protein ligase PIAS2 isoform X1 [Copidosoma floridanum] >gi|936572263|ref|XP_014218501.1| E3 SUMO-protein ligase PIAS2 isoform X1 [Copidosoma floridanum])

HSP 1 Score: 434.106 bits (1115), Expect = 7.989e-141
Identity = 240/532 (45.11%), Postives = 315/532 (59.21%), Query Frame = 0

Query:   49 ESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSIPMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
            E E L +MV SFR+SELQ L+ FAG++KSGRK+ELQARAL+L+ + S  ++LKIREL  ++ +   +A  +           G+S  +A  + E S    N  T  GH        +   + +A+    D+ PA                     AS+ Q+        G RT+P        S   Q +          N  T Q  + +  PL L P+                     YP  PDVK ++LPFF ++  L++P +L P  T R QE    FHL+P Q+++IASS    +  +++Y  Q+QMRF L ETSCEQ+D FP SI VKVN KM PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+AN + V+W+ + GR + +++Y V KL+S +L+  LK RG +H DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCRASTC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F EVL S KL    +E+ L  DGSWE L
Sbjct:    4 EMEELENMVLSFRVSELQMLLGFAGRNKSGRKNELQARALELLRLRSHPVQLKIRELYKSIQADQLAAHQM----------YGQSGAAAEPQIETSMHSRNYFTRQGHAQS----LSQQQSQQAVQPTKDLPPAHQ-------------------ASIPQSQV------GQRTAPVFQTPGYTSVTPQSRTTNPVYPGAYNAYTQQKVMSLPAPLSLQPAQ--------------------YPVHPDVKFKRLPFFDMLGELLKPSSLMPQGTLRLQENSFVFHLTPQQSTDIASSRDCRTGSKMDYTVQVQMRFCLQETSCEQEDYFPPSINVKVNGKMCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVANQISVTWSADYGRRYAIAVYLVKKLTSSELLMRLKNRGCKHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRASTCSHLQCFDASLFLQMNERKPTWNCPVCDKTALYDNLTIDGYFQEVLSSNKLLPDVNEIQLLQDGSWENL 476          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|345498420|ref|XP_003428227.1| (PREDICTED: E3 SUMO-protein ligase PIAS2 isoform X4 [Nasonia vitripennis])

HSP 1 Score: 433.335 bits (1113), Expect = 1.513e-140
Identity = 242/535 (45.23%), Postives = 324/535 (60.56%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSI-PMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
            M+E+E L +MV SFR+SELQ L+ FAG++KSGRK+ELQ RAL+L+ + S  ++LKIREL   + +   +A  +      YS    +S G+A Q+ E++    N  T  GH         A A ++       ++PA+    ++ +    SQ +  S  SV  T    S+   SR++       S  + G               P  Q  + P+  PL + P+                     YP  PDVK ++LPFF ++  L++P +L P  T R QE    FHL+P Q+++IASS       +++Y  Q+QMRF L ETSCEQ+D FP SI VKVN K+ PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+ N + +SW+ + GR + V++Y V KL+S +L+  LK RG +H DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCRASTC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F EVL S KL    +E+ L  DGSWE L
Sbjct:    1 MSETEELENMVLSFRVSELQMLLGFAGRNKSGRKNELQTRALELLRLRSHPVQLKIRELYKTIQADQLAAHQL------YS----QSSGAAEQQIEQTMHSRNYFTRQGH---------AQALSQQQQSQQSVAPAKDLPPAHQASIPQSQVAQRSG-SVYPTPGYTSVTPQSRST-------SAVYPGY-------------SPYAQQKVMPIPAPLQIQPNQ--------------------YPVHPDVKFKKLPFFDMLGELLKPSSLMPQGTMRLQENSFVFHLTPQQSTDIASSRDCRQGSKMDYTVQVQMRFCLQETSCEQEDYFPPSINVKVNGKLCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVGNQITISWSADYGRRYAVAVYLVRKLTSTELLTRLKNRGCKHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRASTCSHLQCFDASLFLQMNERKPTWNCPVCDKSALYDNLTIDGYFQEVLNSNKLLPDVNEIQLLQDGSWENL 475          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|645033299|ref|XP_008214945.1| (PREDICTED: E3 SUMO-protein ligase PIAS2 isoform X2 [Nasonia vitripennis])

HSP 1 Score: 432.565 bits (1111), Expect = 3.640e-140
Identity = 242/538 (44.98%), Postives = 326/538 (60.59%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNT---NGPTTQNSI-PMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
            M+E+E L +MV SFR+SELQ L+ FAG++KSGRK+ELQ RAL+L+ + S  ++LKIREL   + +   +A  +  YS        +S G+A Q+ E++    N  T  GH         A A ++       ++PA+        D   +  +S   + V Q        R     P+  G +S++   Q+  + +R  S       P  Q  + P+  PL + P+                     YP  PDVK ++LPFF ++  L++P +L P  T R QE    FHL+P Q+++IASS       +++Y  Q+QMRF L ETSCEQ+D FP SI VKVN K+ PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+ N + +SW+ + GR + V++Y V KL+S +L+  LK RG +H DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCRASTC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F EVL S KL    +E+ L  DGSWE L
Sbjct:    1 MSETEELENMVLSFRVSELQMLLGFAGRNKSGRKNELQTRALELLRLRSHPVQLKIRELYKTIQADQLAAHQL--YS--------QSSGAAEQQIEQTMHSRNYFTRQGH---------AQALSQQQQSQQSVAPAK--------DLPPAHQASIPQSQVAQ--------RSGSVYPTP-GYTSVT--PQVIDLNSRSTSAVYPGYSPYAQQKVMPIPAPLQIQPNQ--------------------YPVHPDVKFKKLPFFDMLGELLKPSSLMPQGTMRLQENSFVFHLTPQQSTDIASSRDCRQGSKMDYTVQVQMRFCLQETSCEQEDYFPPSINVKVNGKLCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVGNQITISWSADYGRRYAVAVYLVRKLTSTELLTRLKNRGCKHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRASTCSHLQCFDASLFLQMNERKPTWNCPVCDKSALYDNLTIDGYFQEVLNSNKLLPDVNEIQLLQDGSWENL 480          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|951579586|ref|XP_014487438.1| (PREDICTED: E3 SUMO-protein ligase PIAS2 isoform X2 [Dinoponera quadriceps])

HSP 1 Score: 431.409 bits (1108), Expect = 2.213e-139
Identity = 250/590 (42.37%), Postives = 343/590 (58.14%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSA-EIKLKIRELS---HAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSP---------PSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSIPMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPY-KKEGVSSSDREPTPPPSAKIEKVETLNVEDDEVPIPIPPP 621
            MAE+E L +M+ SFR+SELQ L+ FAG++KSGRK+ELQARAL+L+++ S   I+LKIREL    H  YS   +  +   Y + YSG               ++  V  S  S        R   +AA +  S+    +  + DQ+ +  +Y  ++ + +       + S           S+ +  RT+P        +   Q  P      S    P     +P   PL + P+++                   YP  PDV+L++LPFF ++  L++P +L P  + R QE    FHL+P QA++IASS    +  +++Y  Q+QMRF L ETSCEQ+D FP +I VKVN+K+ PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+ N + VSW+ + GR F V++Y V KL+S +L+  LK RG RH DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRM  PCRASTC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F EVL S KL    +E+ L  DGSWE L   K++       E      ++ +K++   V+ DE  +  P P
Sbjct:    1 MAENEELENMILSFRVSELQMLLGFAGRNKSGRKNELQARALELLHLRSHPAIRLKIRELYKTIHTSYSIHDADRTAFIYKSRYSG---------------TSLYVRSSNSSCRYDKPYVRQDQMAAHQIYSQTGSSTEPQIDQTMHNRNYYSTRQAMSQQQQSQASVSAGKELTPAHQASIPQAPRTNPVYQSTGYTNVTAQRAPSAGYAYS----PYPPKVLP--SPLQMQPATQ-------------------YPVHPDVRLKKLPFFDLLGELLKPSSLMPQGSLRLQENTFMFHLTPQQATDIASSRDCRAGSKMDYIVQVQMRFCLQETSCEQEDYFPPNITVKVNSKLCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVGNEIRVSWSADYGRRFAVAVYLVRKLTSAELLSRLKNRGARHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMCTPCRASTCSHLQCFDASLFLQMNERKPTWNCPVCDKSALYDNLVIDGYFQEVLNSNKLLPDVNEIQLLQDGSWENLVLKKEKDKDKEKNEAKAAADSREDKIDVDTVDLDETNLTTPAP 550          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|936572266|ref|XP_014218502.1| (E3 SUMO-protein ligase PIAS2 isoform X2 [Copidosoma floridanum] >gi|936572269|ref|XP_014218503.1| E3 SUMO-protein ligase PIAS2 isoform X2 [Copidosoma floridanum] >gi|936572272|ref|XP_014218504.1| E3 SUMO-protein ligase PIAS2 isoform X2 [Copidosoma floridanum])

HSP 1 Score: 429.483 bits (1103), Expect = 3.499e-139
Identity = 237/525 (45.14%), Postives = 311/525 (59.24%), Query Frame = 0

Query:   56 MVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSIPMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
            MV SFR+SELQ L+ FAG++KSGRK+ELQARAL+L+ + S  ++LKIREL  ++ +   +A  +           G+S  +A  + E S    N  T  GH        +   + +A+    D+ PA                     AS+ Q+        G RT+P        S   Q +          N  T Q  + +  PL L P+                     YP  PDVK ++LPFF ++  L++P +L P  T R QE    FHL+P Q+++IASS    +  +++Y  Q+QMRF L ETSCEQ+D FP SI VKVN KM PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+AN + V+W+ + GR + +++Y V KL+S +L+  LK RG +H DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCRASTC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F EVL S KL    +E+ L  DGSWE L
Sbjct:    1 MVLSFRVSELQMLLGFAGRNKSGRKNELQARALELLRLRSHPVQLKIRELYKSIQADQLAAHQM----------YGQSGAAAEPQIETSMHSRNYFTRQGHAQS----LSQQQSQQAVQPTKDLPPAHQ-------------------ASIPQSQV------GQRTAPVFQTPGYTSVTPQSRTTNPVYPGAYNAYTQQKVMSLPAPLSLQPAQ--------------------YPVHPDVKFKRLPFFDMLGELLKPSSLMPQGTLRLQENSFVFHLTPQQSTDIASSRDCRTGSKMDYTVQVQMRFCLQETSCEQEDYFPPSINVKVNGKMCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVANQISVTWSADYGRRYAIAVYLVKKLTSSELLMRLKNRGCKHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRASTCSHLQCFDASLFLQMNERKPTWNCPVCDKTALYDNLTIDGYFQEVLSSNKLLPDVNEIQLLQDGSWENL 466          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|817196461|ref|XP_012273818.1| (E3 SUMO-protein ligase PIAS1 isoform X1 [Orussus abietinus])

HSP 1 Score: 427.943 bits (1099), Expect = 1.574e-138
Identity = 245/536 (45.71%), Postives = 328/536 (61.19%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGG--GRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSIPMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
            MAESE L +MV SFR+SELQ L+ FAG++KSGRK+ELQARAL+L+ + S  ++LKIREL   + +    A  +           G+S G++  + +++    N  T  GH    G+ +  A+++A +      ++SPA                         Q   PPS     R++P     +  +   Q      R  S+T  P   ++  +SQPL                P ++PN    YP  PDV+L++LPFF ++  L++P +L P  T R QE    FHL+P Q+++IASS    +  +++Y  Q+QMRF L ETSCEQDD FP +I VKVN K+ PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+ N + V+W+ + GR + +++Y V KLSS +L+  LK RG+RH DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCRASTC HLQCFDA+LFL MNERKP W CPVC+K A +DNL IDG+F EVL S KL    +EV L  DGSWE L
Sbjct:    1 MAESEELENMVLSFRVSELQMLLGFAGRNKSGRKNELQARALELLRLRSHPVQLKIRELYKTIQADQLVAHQM----------YGQSGGTSEPQVDQTMHSRNYYTRQGHAQAMGQQQSQASISATK------ELSPAH------------------------QASIPPSQV-TPRSTPVYQPTNYSNVTSQ-----QRSASSTYNPYPFSTKVLSQPL----------------PIQQPNQ---YPVHPDVRLKKLPFFDLLGELLKPSSLVPQGTIRVQENTFMFHLTPQQSTDIASSRDCRAGSKMDYTVQVQMRFCLQETSCEQDDYFPPNIGVKVNGKLCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVGNQIHVTWSADYGRRYAIAVYLVKKLSSSELLSRLKCRGVRHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRASTCSHLQCFDASLFLQMNERKPTWSCPVCDKAAFYDNLVIDGYFQEVLSSNKLLPDVNEVQLLQDGSWENL 471          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|345498422|ref|XP_001607391.2| (PREDICTED: E3 SUMO-protein ligase PIAS2 isoform X3 [Nasonia vitripennis])

HSP 1 Score: 426.017 bits (1094), Expect = 9.877e-138
Identity = 241/535 (45.05%), Postives = 322/535 (60.19%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSI-PMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
             +E E L+ MV SFR+SELQ L+ FAG++KSGRK+ELQ RAL+L+ + S  ++LKIREL   + +   +A  +      YS    +S G+A Q+ E++    N  T  GH         A A ++       ++PA+    ++ +    SQ +  S  SV  T    S+   SR++       S  + G               P  Q  + P+  PL + P+                     YP  PDVK ++LPFF ++  L++P +L P  T R QE    FHL+P Q+++IASS       +++Y  Q+QMRF L ETSCEQ+D FP SI VKVN K+ PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+ N + +SW+ + GR + V++Y V KL+S +L+  LK RG +H DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCRASTC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F EVL S KL    +E+ L  DGSWE L
Sbjct:    3 FSELEYLN-MVLSFRVSELQMLLGFAGRNKSGRKNELQTRALELLRLRSHPVQLKIRELYKTIQADQLAAHQL------YS----QSSGAAEQQIEQTMHSRNYFTRQGH---------AQALSQQQQSQQSVAPAKDLPPAHQASIPQSQVAQRSG-SVYPTPGYTSVTPQSRST-------SAVYPGY-------------SPYAQQKVMPIPAPLQIQPNQ--------------------YPVHPDVKFKKLPFFDMLGELLKPSSLMPQGTMRLQENSFVFHLTPQQSTDIASSRDCRQGSKMDYTVQVQMRFCLQETSCEQEDYFPPSINVKVNGKLCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVGNQITISWSADYGRRYAVAVYLVRKLTSTELLTRLKNRGCKHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRASTCSHLQCFDASLFLQMNERKPTWNCPVCDKSALYDNLTIDGYFQEVLNSNKLLPDVNEIQLLQDGSWENL 476          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|645033319|ref|XP_008214950.1| (PREDICTED: E3 SUMO-protein ligase PIAS2 isoform X6 [Nasonia vitripennis] >gi|645033322|ref|XP_008214951.1| PREDICTED: E3 SUMO-protein ligase PIAS2 isoform X6 [Nasonia vitripennis])

HSP 1 Score: 425.246 bits (1092), Expect = 1.379e-137
Identity = 238/526 (45.25%), Postives = 317/526 (60.27%), Query Frame = 0

Query:   56 MVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIRELSHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEPERSASPVNLSTESGHGGGRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSI-PMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPL 579
            MV SFR+SELQ L+ FAG++KSGRK+ELQ RAL+L+ + S  ++LKIREL   + +   +A  +      YS    +S G+A Q+ E++    N  T  GH         A A ++       ++PA+    ++ +    SQ +  S  SV  T    S+   SR++       S  + G               P  Q  + P+  PL + P+                     YP  PDVK ++LPFF ++  L++P +L P  T R QE    FHL+P Q+++IASS       +++Y  Q+QMRF L ETSCEQ+D FP SI VKVN K+ PLPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+ N + +SW+ + GR + V++Y V KL+S +L+  LK RG +H DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCRASTC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F EVL S KL    +E+ L  DGSWE L
Sbjct:    1 MVLSFRVSELQMLLGFAGRNKSGRKNELQTRALELLRLRSHPVQLKIRELYKTIQADQLAAHQL------YS----QSSGAAEQQIEQTMHSRNYFTRQGH---------AQALSQQQQSQQSVAPAKDLPPAHQASIPQSQVAQRSG-SVYPTPGYTSVTPQSRST-------SAVYPGY-------------SPYAQQKVMPIPAPLQIQPNQ--------------------YPVHPDVKFKKLPFFDMLGELLKPSSLMPQGTMRLQENSFVFHLTPQQSTDIASSRDCRQGSKMDYTVQVQMRFCLQETSCEQEDYFPPSINVKVNGKLCPLPNPIPTNKPGVEPKRPPRPVNISPLVKLSPTVGNQITISWSADYGRRYAVAVYLVRKLTSTELLTRLKNRGCKHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRASTCSHLQCFDASLFLQMNERKPTWNCPVCDKSALYDNLTIDGYFQEVLNSNKLLPDVNEIQLLQDGSWENL 466          

BLAST of e3 sumo-protein ligase pias2 isoform x6 vs. nr
Match: gi|1000741953|ref|XP_015593609.1| (PREDICTED: E3 SUMO-protein ligase PIAS1 isoform X5 [Cephus cinctus])

HSP 1 Score: 425.246 bits (1092), Expect = 1.744e-137
Identity = 266/646 (41.18%), Postives = 357/646 (55.26%), Query Frame = 0

Query:   47 MAESEVLHSMVRSFRMSELQNLMAFAGKSKSGRKSELQARALDLVNVNSAEIKLKIREL----------SHAMYSSLGSAASVNPYSANYSGEVGRSLGSASQEP--ERSASPVNLSTESGHGG--GRTRRSAAVAAARAMSRVSDISPAESDQSSNGSDYSDSQSSSASAASVVQTDSPPSLARGSRTSPSGMGASSLSFAGQIQPVRNRGKSNTNGPTTQNSIPMSQPLGLMPSSRISPGRSVKDPSEEPNSHLMYPTFPDVKLRQLPFFKVMATLMQPCALQPGSTARFQEQKLSFHLSPSQASEIASSSFRDSLGRVEYKKQIQMRFSLLETSCEQDDNFPASICVKVNNKMQPLPNPIPTNKPGVEPKRPPKPINITALCKLSSTMANYLDVSWAVEIGRGFTVSIYYVDKLSSLDLMKDLKERGIRHPDYTRAVIKEKLN-DKDVDVMTTSCKVTLACPLGKMRMSYPCRASTCDHLQCFDANLFLMMNERKPKWLCPVCNKGALFDNLQIDGFFNEVLKSAKLPAHDHEVVLHNDGSWEPLPYKKEGVSSSDREPTPPPSAKIEKVETLNVEDDEVPIPIPPPAVNNGHSDLGSLPGVSPKTKNDKRSFDCITLDSDSDDEGPETRPPNRKRATAGETS 677
            MAE+E L +MV SFR+SELQ L+ FAG++KSGRK+ELQ RAL+L+ + S  ++LKIREL          +H +YS  G AA                      EP  +++    N  T  GH    G+ +  ++VAA +      D+ PA                     AS+ Q+         +RT+P    A   S   Q      R  S    P    +        ++P     P   ++ PS+       YP  PDVKL++LPFF ++  L++P +L P  + R QE    FHL+P Q+++IASS    +  +++Y  Q+QMRF L ETSCEQ+D FP SI VKVN K   LPNPIPTNKPGVEPKRPP+P+NI+ L KLS T+ N + V+W+ +  R + +++Y V KLSS +L+  LK RG RH DYTR +IKEKLN D D ++ TTS +V+LACPLGKMRMS PCR+STC HLQCFDA+LFL MNERKP W CPVC+K AL+DNL IDG+F +VL S+KL    +E+ L  DGSWE L      V   +++      ++I     ++V  D V              DL     +SP  K  KR+   I L SDSDDE       + K+  +G TS
Sbjct:    1 MAETEELENMVLSFRVSELQMLLGFAGRNKSGRKNELQTRALELLRLRSHPVQLKIRELYKTIQADQLAAHQLYSQTGGAA----------------------EPAIDQNMHSRNYYTRQGHAQAMGQQQPQSSVAATK------DLPPAHQ-------------------ASLPQSQV------SARTNPVYPAAGYTSVTPQ-----QRSTSAVYSPYPYQA-------KVLP-----PQLQIQQPSQ-------YPVHPDVKLKKLPFFDMLGELLKPSSLMPQGSMRLQESSFMFHLTPQQSTDIASSRDCRAGSKMDYTVQVQMRFCLQETSCEQEDYFPPSIAVKVNGKPCALPNPIPTNKPGVEPKRPPRPVNISQLVKLSPTVGNQIQVTWSADYNRRYAIAVYLVRKLSSSELLTRLKTRGARHSDYTRGLIKEKLNEDADSEIATTSLRVSLACPLGKMRMSTPCRSSTCSHLQCFDASLFLQMNERKPTWSCPVCDKPALYDNLVIDGYFQDVLSSSKLLPDVNEIQLLQDGSWENL------VLKKEKDKDKELKSEINSHNKIDV--DTV--------------DLDESNPISPTPKEKKRAV-IIDLISDSDDEDSNPSQSSNKKFASGLTS 546