BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000010753 (supercontig:LSalAtl2s:LSalAtl2s712:509674:515656:1 gene:EMLSAG00000010753 transcript:EMLSAT00000010753 description:"snap_masked-LSalAtl2s712-processed-gene-5.30")

HSP 1 Score: 486.878 bits (1252), Expect = 2.238e-158
Identity = 275/664 (41.42%), Postives = 399/664 (60.09%), Query Frame = 0

Query:   98 YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEED--LPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAG-EIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPK------DRPEDMQMFVKKSLQGLEDLRQI-PLEGR-KEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQ 750
            ++ + Q  SG FG+V VW H+++   LA KKCR G    LS   REQW  EV IL +L HPNV+KS   P D    EED  LPL+ ME+CSGGDLR  LN   +  GL + +VLAI  DL SALG+LHNRRIIHRDLKPENVV+     R IYKLIDLGYAK+L QSSLA + VGTLQY+APE ++  +YTKSVDYWSLG ++HEI+TG RPFLP+  PG+WME VE K +  IC+ +  D + + F    F EN++S +L  D   WL+SLLEW+   RG+NE   EI +F DL  IL+  R+++V +D   NK+D+++   +    L   +E+   I    Q+LL  NG  +L  E  L      +P    +Y   +     + +KI      +P  ++S LK+P+++V+   ++ IY+H Y+   QE     +     ++LI+ LL  +K LN ++Q + +  E+A+SK++LF+ESL +D EKY+EQ  +   ITSA+++++W++ E +L      ++  +Q+V     E+  +  EI+ + K      D   D++ F  KSL   E L++  P  GR  E   V+++A     CLK+RD  L+ +F     +    + +      ++     L++F++ VSK QRKRQSD+WKLL+AALQ
Sbjct:    7 WILENQSRSGGFGIVSVWVHKENKFRLAXKKCRLGKS--LSTNLREQWINEVAILGQLNHPNVIKSFPPPSDFKDKEEDSSLPLLFMEYCSGGDLRATLNTCENATGLQEVQVLAIISDLTSALGYLHNRRIIHRDLKPENVVIHIEKGRVIYKLIDLGYAKKLDQSSLAQTIVGTLQYLAPEFYMGNKYTKSVDYWSLGLITHEIVTGVRPFLPDYPPGKWMEVVENKNRETICIPELND-ERVEF----FLENNISESLQRDLAQWLQSLLEWDANLRGKNEVSEEITVFSDLNSILNCSRIKIVFLDNSLNKMDFVVENESSVDSLCEIIEKRVHIPKMCQILLTRNGNRLLCLEPFLKEKELGQPLCATVYVTDTRIITDIKEKISSYGFIIPDAVKSALKSPKEKVDFKTKRRIYAHGYYLLRQEEANHENSVVGTRILIVHLLNELKILNNSSQGLLKLFEKAVSKFDLFKESLNYDIEKYKEQATRRQRITSAKIYDSWSKPEPNLE---KQLKYIQQDVASFEKEIININQEIRNLQKSSSFKVDSCPDLKEFCAKSLTLCESLKKFSPSNGRPSESSNVVEMAXLXXICLKRRDEILRKHFTLLNQILIHVNAISSLMPKIEVSKNQLEIFLMAVSKSQRKRQSDVWKLLSAALQ 660          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000010271 (supercontig:LSalAtl2s:LSalAtl2s680:142787:148655:-1 gene:EMLSAG00000010271 transcript:EMLSAT00000010271 description:"maker-LSalAtl2s680-augustus-gene-1.23")

HSP 1 Score: 112.079 bits (279), Expect = 2.317e-25
Identity = 97/372 (26.08%), Postives = 173/372 (46.51%), Query Frame = 0

Query:   96 GEYV-CQTQ-LGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDL----PLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVV-LQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELF--------LSQEYTKSVDYWSLGFLSHEIMTGRRPFLP---NLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKD-LQTWLERDTGIHVGHQLLLMPNGQEI 448
              YV C T  LG G+ G V    ++ +G+ +A+K     + +    + +E   +E ++LQ+++H N+VK       LL +EE+      ++ ME C+GG L  +L+ P +  GL + E L +   L++ +  L +  ++HRDLKP N++         +YKL D G A+EL      +S  GT +Y+ P+++        + + +  +VD WS+G   + + TG  PF P     +         KK+   I   Q  +   I +   L     LSA + +     L  LLE  P++R   E      F  +  IL + ++ +  +++      Y+ R  T+G D  +T L   T I   + ++++    E+
Sbjct:    8 ANYVWCTTSVLGKGATGAVFQGVNKHNGETVAVKTFNQLSHM----RPQEVQMREFEVLQKVKHENIVK-------LLAIEEEQEGRGKVIVMELCTGGSLFNLLDDPENSYGLHEDEWLXVLSHLSAGMNHLRDNNLVHRDLKPGNIMKFIKDDGNIVYKLTDFGAARELEDDQQFVSLYGTEEYLHPDMYERAVLRKTVGKTFGATVDLWSIGVTLYHVATGNLPFRPFGGRRNKETMYHITTKKSSGVISGVQTSENGPIQWSRELPNSCLLSAGIKKHITPLLAGLLEVNPQKRWTFER----FFSQVTWILDKKKLHIYFMNKLTPHRIYLDR--TEGLDTFKTILSEQTEISPDNDMIILFGENEL 362          

HSP 2 Score: 93.9745 bits (232), Expect = 8.908e-20
Identity = 58/171 (33.92%), Postives = 97/171 (56.73%), Query Frame = 0

Query:  148 EVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWM 318
            EV ++++LEHPN+V  +    DL   +++L  + M++ +GG L  ++   +H   L + ++ AI+ ++ S + +LHN  +IHRD+K +NV+L     +   K+ D G+   +    +  +F GT  ++APE+   Q Y KSVD WSLG L  E M  R P   + +P Q M
Sbjct: 1056 EVQVMRKLEHPNLVAFL----DLFLTDKEL-WVVMDYMNGGPLTDVV---LHTI-LNEPQMSAISKEVLSGINYLHNHELIHRDIKSDNVLLSV---KGDVKITDFGFTANVSGDRMRKTFAGTPYWMAPEVVKKQTYGKSVDIWSLGILVIE-MVDRHPPYMDETPLQAM 1213          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000008721 (supercontig:LSalAtl2s:LSalAtl2s541:438808:485939:-1 gene:EMLSAG00000008721 transcript:EMLSAT00000008721 description:"maker-LSalAtl2s541-augustus-gene-3.15")

HSP 1 Score: 112.464 bits (280), Expect = 2.452e-25
Identity = 69/211 (32.70%), Postives = 109/211 (51.66%), Query Frame = 0

Query:   98 YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308
            Y    ++G+G+FGVVH  R  K+GQ+ A K       +      +   R+E+DI+  L H  ++       D    EE++ ++  EF SGG+L + +    +   + + EV+     +   + F+H R IIH D+KPENV+ Q T K T  KLID G A +L  + L     GT ++ APE+   +      D WS+G LS+ +++G  PF
Sbjct: 8428 YDILEEIGTGAFGVVHRCRESKTGQVYAAKFIPISHAM-----EKALIRKEIDIMNHLHHNKLINLH----DAYEDEEEM-VLIFEFLSGGELFEKITSEGYT--MSEAEVINYMRQICEGVKFMHERNIIHLDIKPENVMCQ-TSKSTNVKLIDFGLATKLDPNELVKISTGTAEFAAPEIVEREPVGFYTDMWSIGVLSYVLLSGLSPF 8625          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000003715 (supercontig:LSalAtl2s:LSalAtl2s1:3290800:3325247:1 gene:EMLSAG00000003715 transcript:EMLSAT00000003715 description:"maker-LSalAtl2s1-augustus-gene-33.19")

HSP 1 Score: 107.071 bits (266), Expect = 1.829e-24
Identity = 72/210 (34.29%), Postives = 110/210 (52.38%), Query Frame = 0

Query:  104 LGSGSFGVVHVWRHQKSGQILALK---KCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLP--LMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308
            LGSG FG+V+   H+++G+ +A+K   K RF +      K     + EV ILQ + HP VV       +L R+ E L    + ME   G D+ +M+    H   L +     +   +  AL  LH++ I+H DLKPENV+L         KL D G+A+ +G+     S VGT  Y+APE+  ++ Y +S+D WS G + +  ++G  PF
Sbjct:  198 LGSGQFGIVYGGVHRQNGEAVAVKVIDKMRFPS------KQEAALKNEVSILQNIHHPGVV-------NLERMFETLERIYVVMEKLKG-DMLEMILSSEHG-RLSERVTKFVVTQILVALKHLHSKNIVHCDLKPENVLLSSNSDFPQVKLCDFGFARIIGEKGFRKSVVGTPAYLAPEVLRNKGYNRSLDMWSTGVIIYVSLSGTFPF 392          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000011184 (supercontig:LSalAtl2s:LSalAtl2s760:424402:425388:1 gene:EMLSAG00000011184 transcript:EMLSAT00000011184 description:"augustus_masked-LSalAtl2s760-processed-gene-3.6")

HSP 1 Score: 103.219 bits (256), Expect = 4.014e-24
Identity = 71/217 (32.72%), Postives = 115/217 (53.00%), Query Frame = 0

Query:   95 LGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKML-NMPVHCCGLPQGEVLA--ITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308
            L ++     LG G FG V++ R +KS  I+ALK   F   +  +     Q R+E++I   L HP++++      D  R+      + +EF S G+L K+L N P+        E LA      ++ AL +LH++++IHRD+KPEN++L     +   K+ D G++     SS   +  GTL Y++PE+   + + + VD WSLG L  E + G+ PF
Sbjct:   50 LNDFDIGRPLGKGKFGNVYLAREKKSKFIVALK-VMFKNQLKKANVE-HQLRREIEIQXHLRHPHILRLYGYFYDETRV-----YLILEFASKGELYKLLKNEPLKRFE----ETLAARYIYQMSGALDYLHSKKVIHRDIKPENLLLD---SKGNLKIADFGWSVH-APSSRRGTMCGTLDYLSPEMIEGRSHDEKVDLWSLGILCFEFLVGKPPF 251          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000009407 (supercontig:LSalAtl2s:LSalAtl2s5:303399:304469:-1 gene:EMLSAG00000009407 transcript:EMLSAT00000009407 description:"augustus-LSalAtl2s5-processed-gene-3.1")

HSP 1 Score: 102.449 bits (254), Expect = 1.079e-23
Identity = 75/243 (30.86%), Postives = 119/243 (48.97%), Query Frame = 0

Query:   94 RLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPG----------QWMEQVEKKTK 326
            RL ++  +  +G+G+F  V + +H+ +    ALK       V L  K  E  + E +IL  L HP +V  +   KD   L      M   + SGG+L   L        +P    L    ++  AL +LH++ I++RDLKPEN++L    +    K+ D G+AK +   +  L   GT +Y+APE+  S+ + ++VD+WSLG L +E++ G  PF  +   G           W  Q+E  TK
Sbjct:   43 RLEDFELRETIGTGTFARVCLVKHKFTHAYYALKILSIKDVVRL--KQVEHVKNETNILSELRHPYIVNLVWKYKDPKFL-----YMVFPYISGGELFSYLRT-AGRFNVPTS--LFYISEIVCALEYLHSQSIVYRDLKPENLLLD---RDGHLKITDFGFAKRISDRTWTL--CGTPEYLAPEIIQSKGHNRAVDWWSLGILIYEMLAGYPPFFDDNPFGIYEKILGGKIDWPRQMEPVTK 270          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000006879 (supercontig:LSalAtl2s:LSalAtl2s389:561753:579552:-1 gene:EMLSAG00000006879 transcript:EMLSAT00000006879 description:"maker-LSalAtl2s389-snap-gene-5.36")

HSP 1 Score: 102.064 bits (253), Expect = 1.970e-22
Identity = 69/215 (32.09%), Postives = 114/215 (53.02%), Query Frame = 0

Query:   95 LGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYT-KSVDYWSLGFLSHEIMTGRRPF 308
            +G+Y     +G G+F  V + RH  +G+ +A+K         L+    ++  +EV I++ L+HPN+VK   V    +  E+ L L+ ME+ SGG++   L   V    + + E  A    + SA+ + H ++IIHRDLK EN++L         K+ D G++ E    +   +F G+  Y APELF  ++Y    VD WSLG + + +++G  PF
Sbjct:  116 IGKYRLLKTIGKGNFAKVKLARHTATGKEVAIKII---DKTQLNPGSLQKLFREVRIMKTLDHPNIVKLFQV----IETEKTLYLV-MEYASGGEVFDYL---VLHGRMKEKEARAKFRQIVSAVQYCHQKKIIHRDLKAENLLLD---SEMNIKIADFGFSNEFIPGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF 316          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000004239 (supercontig:LSalAtl2s:LSalAtl2s222:1379053:1391929:1 gene:EMLSAG00000004239 transcript:EMLSAT00000004239 description:"maker-LSalAtl2s222-augustus-gene-13.20")

HSP 1 Score: 101.679 bits (252), Expect = 2.277e-22
Identity = 73/208 (35.10%), Postives = 113/208 (54.33%), Query Frame = 0

Query:  104 LGSGSFGVVHVWRH---QKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308
            LG GSFG V + R    + SG + A+K  +  T   L  + R + ++E DIL  +EHP +VK         + E  L L+ ++F  GGDL   L+  +      + +V     +LA AL  LH+  II+RDLKPEN++L       +    D G +KE  +   A SF GT++Y+APE+   + ++ + D+WS G L +E++TG+ PF
Sbjct:   88 LGQGSFGKVFLVRKIEGKDSGTLYAMKVLKKAT---LRFRDRVRTKKERDILAEIEHPFMVKLYYA----FQTEGKLYLI-LDFLRGGDLFTRLSKEIM---FTEEDVKFYLAELALALIHLHSLGIIYRDLKPENLLLDSNGHIAV---TDFGLSKETIEDK-AYSFCGTVEYMAPEIVNRKGHSFAADWWSFGILMYEMLTGQLPF 280          

HSP 2 Score: 90.8929 bits (224), Expect = 5.395e-19
Identity = 67/233 (28.76%), Postives = 113/233 (48.50%), Query Frame = 0

Query:   97 EYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRL-EHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDL-RKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTH-KRTIYKLIDLGYAKEL-GQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFL--PNLSPGQWMEQVEK 323
            EY  +  +G GS+       H+ +    A+K         + +  R+    EV+IL R  +HPN++    V +D     +D   +  E+  GG+L  K+L   +      + E  +I   L SA+ +LH   ++HRDLKP N++           ++ D G+AK+L   + L ++   T  Y+APE+   Q Y  + D WSLG L H +++G+ PF   PN S    + ++E+
Sbjct:  436 EYEVKELIGVGSYSECKRCIHKATNVEYAMK--------VIDKSKRDCNSDEVEILLRYGQHPNIISLKDVFED-----KDFAYLIFEYMRGGELLDKILQQEI----FSEREARSIMERLTSAVHYLHQNGVVHRDLKPANILYADKFGDPNTLRICDFGFAKQLRADNGLLMTPCYTANYVAPEVLKQQGYDAACDVWSLGVLLHIMLSGKAPFANGPNDSMEVILSRIEE 651          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000005433 (supercontig:LSalAtl2s:LSalAtl2s292:565959:573639:1 gene:EMLSAG00000005433 transcript:EMLSAT00000005433 description:"maker-LSalAtl2s292-augustus-gene-5.11")

HSP 1 Score: 95.1301 bits (235), Expect = 1.788e-21
Identity = 65/217 (29.95%), Postives = 110/217 (50.69%), Query Frame = 0

Query:   94 RLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGL-PQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLAL-SFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308
            +L  +  + ++G G F VV+  + +   + +ALKK +      +  K R    +E+ +LQ+L+HPNVV+ ++       +E +   + +E    GDL  M+        L P+  +      + SAL ++H++RI+HRD+KP NV +    +    KL DLG  +    +++A  S VGT  Y++PE    + Y    D WSLG L +E+     PF
Sbjct:   18 KLENFNVEKRIGKGQFSVVYRAKCKVDKRTVALKKVQILE--MMDSKARVDCVKEILLLQQLDHPNVVRYLAS-----FIENNELNIVLELADAGDLSWMIKYFKKSRKLLPEKTIWKYFVQICSALDYMHSKRIMHRDIKPANVFITANGEA---KLGDLGLGRFFSSNTMAAHSLVGTPYYMSPERIHEEGYNFKSDIWSLGCLLYEMAALHSPF 224          

BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000012530 (supercontig:LSalAtl2s:LSalAtl2s922:67995:142257:1 gene:EMLSAG00000012530 transcript:EMLSAT00000012530 description:"maker-LSalAtl2s922-augustus-gene-1.7")

HSP 1 Score: 95.5153 bits (236), Expect = 1.475e-20
Identity = 68/210 (32.38%), Postives = 104/210 (49.52%), Query Frame = 0

Query:  104 LGSGSFGVVHVWR-----HQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308
            LG G FG V + +      ++S  +  +KK +      +  + ++    E +I++  +   +VK     KD   L      M ME C GG+L  +L                 T  +  A  +LH+R II+RDLKPEN++L  T      KL+D G+AK+L       +F GT +Y+APE+ L++ +  S DYWSLG L  E++TG  PF
Sbjct:  356 LGVGGFGRVELVQIAGDPKKRSFALKQMKKYQI-----VETRQQQHIMSEKEIMEESDCHFIVKLFKTFKDRKYL-----YMLMESCLGGELWTILR---DRGNFDDSTTRFYTACVIEAFDYLHSRGIIYRDLKPENLLLDTTG---YVKLVDFGFAKKLQVGRKTWTFCGTPEYVAPEVILNKGHDISADYWSLGVLMFELLTGTPPF 549          

BLAST of IKKbeta vs. SwissProt
Match: gi|14285495|sp|Q9QY78.1|IKKB_RAT (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB)

HSP 1 Score: 329.717 bits (844), Expect = 5.117e-100
Identity = 246/747 (32.93%), Postives = 382/747 (51.14%), Query Frame = 0

Query:   91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN-EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFS--------TLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFF--NDIRSKRQEV----NDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFN------KKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNG-----------RSGNHQSVSSSPMASIPMPQHQGDEASMILYAENQALRAQLQEYMK 804
            P    G +  + +LG+G FG V  W +Q +G+ +A+K+CR      LS K+R++W  E+ I++RL HPNVV +  VP+ +  L   DLPL+ ME+C GGDLR+ LN   +CCGL +G +L +  D+ASAL +LH  RIIHRDLKPEN+VLQ   KR I+K+IDLGYAKEL Q SL  SFVGTLQY+APEL   Q+YT +VDYWS G L+ E +TG RPFLPN  P QW  +V +K++ DI V +  +          FP N+L++ LAE  E WL+ +L W+P++RG + + G  G F+ L +IL+   V ++ +   G    Y + E    + L+T +  DTGI    Q LL   G  +LP++      S        TL+ +L  ++  S      M+ + +      P+++   L+ P++ ++    + ++   +              Q  +  ++ LL     L+     +A   ++  +K + F+ S+  D EKY+EQ   +  ITS ++  AW + E+ +      ND++   + +     DI+      +G  Q    D  E+      ++ +    LR+ P + R E D+     Q+MVR L Q  ++ +           K  + K  +L  L +V     + N D     V + Q KRQ +LW LL  A  + +   +G             G+  S  SS   S+P      D+ S  L AE  AL ++L+  ++
Sbjct:    8 PTQTCGAWEMKERLGTGGFGNVIRWHNQVTGEQIAIKQCRQE----LSPKNRDRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSSPFP-NNLNSVLAERLEKWLQLMLTWQPRQRGVDPQYGPNGCFRALDDILNLKLVHILNM-VTGTIHTYPVMEDESLQSLKTRIREDTGILETDQELLQEAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLFDNSK-----MSYETQITPRPQPESVSCVLQEPKRNLSFFQMRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNAMASTAQQLKAKLDFFKTSIQIDLEKYREQT--EFGITSDKLLLAWREMEQAVEQCGRENDVKVLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEE------QARELYRRLREKPRDQRTEGDS-----QDMVRLLLQAIQSFEKKVRVIYSQLSKTVVCKQKALELLPKVEEVVRLMNED--EKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNVSRLSHPGHLMSQPSSACDSLP----DSDKKSEELVAEAHALCSRLESALQ 724          

BLAST of IKKbeta vs. SwissProt
Match: gi|14285499|sp|O88351.1|IKKB_MOUSE (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB)

HSP 1 Score: 329.717 bits (844), Expect = 6.436e-100
Identity = 248/740 (33.51%), Postives = 378/740 (51.08%), Query Frame = 0

Query:   91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTD-EIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN-EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLT---MPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDL------NDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFN------KKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVS--SSPMASIPMPQH------QGDEASMILYAENQALRAQLQEYMK 804
            P    G +  + +LG+G FG V  W +Q +G+ +A+K+CR      LS K+R +W  E+ I++RL HPNVV +  VP+ +  L   DLPL+ ME+C GGDLR+ LN   +CCGL +G VL +  D+ASAL +LH  RIIHRDLKPEN+VLQ   KR I+K+IDLGYAKEL Q SL  SFVGTLQY+APEL   Q+YT +VDYWS G L+ E +TG RPFLPN  P QW  +V +K++ DI V   ED +  + F   L   N+L++ LAE  E WL+ +L W P++RG + + G  G F+ L +IL+   V V+ +   G    Y + E    + L+T ++ +TGI    Q LL   G  +LP++      S  + N  +      +  L  +      ++T    P+++   L+ P++ ++    + ++   +              Q  +  ++ LL     L+     +A   ++  +K + F+ S+  D EKY+EQ   +  ITS ++  AW + E+ +      ND  + +        DI+      +G  Q    D  E+      ++ +    LR+ P + R E D+     Q MVR L Q  ++ +           K  + K  +L  L +V     + N D     V + Q KRQ +LW LL  A   K +G    S +  +VS  S P   +  P        + D+ S  L AE  AL ++L+  ++
Sbjct:    8 PTQTCGAWEMKERLGTGGFGNVIRWHNQATGEQIAIKQCRQE----LSPKNRNRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAVLTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVS--EDLNGAVKFSSSLPFPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPQYGPNGCFRALDDILNLKLVHVLNM-VTGTVHTYPVTEDESLQSLKTRIQENTGILETDQELLQKAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLLDNSKINYETQITPRPPPESVSCILQEPKRNLSFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMSLLRNNSCLSKMKNAMASTAQQLKAKLDFFKTSIQIDLEKYKEQT--EFGITSDKLLLAWREMEQAVEQCGRENDVKHLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEE------QARELYRKLREKPRDQRTEGDS-----QEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDERT--VVRLQEKRQKELWNLLKIAC-SKVRGPVSGSPDSMNVSRLSHPGQLMSQPSSACDSLPESDKKSEELVAEAHALCSRLESALQ 724          

BLAST of IKKbeta vs. SwissProt
Match: gi|14285497|sp|O14920.1|IKKB_HUMAN (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB)

HSP 1 Score: 328.176 bits (840), Expect = 1.877e-99
Identity = 237/721 (32.87%), Postives = 373/721 (51.73%), Query Frame = 0

Query:   96 GEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTD-EIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEA-GEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFS--------TLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGM---VGEIQAIPKDRPEDMQM--FVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFN------KKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNG-----------RSGNHQSVSSSPMASIPMPQHQGDE 783
            G +  + +LG+G FG V  W +Q++G+ +A+K+CR      LS ++RE+W  E+ I++RL HPNVV +  VP+ +  L   DLPL+ ME+C GGDLRK LN   +CCGL +G +L +  D+ASAL +LH  RIIHRDLKPEN+VLQ   +R I+K+IDLGYAKEL Q SL  SFVGTLQY+APEL   Q+YT +VDYWS G L+ E +TG RPFLPN  P QW  +V +K++ DI V   ED +  + F   L   N+L++ LAE  E WL+ +L W P++RG +   G  G FK L +IL+   V ++ +   G    Y + E    + L+  +++DTGI    Q LL   G  ++P++      S        TL+ +L  ++  S +T  T      +     P+++   L+ P++ +     + ++   +              Q  +  ++ LL     L+     +A   ++  +K + F+ S+  D EKY EQ   +  ITS ++  AW + E+ +     ++  +  EV  ++  +  +   + ++Q  P  R +   +    +++ +    LR+ P + R E D     +Q MVR L Q  ++ +           K  + K  +L  L +V     + N D     V + Q KRQ +LW LL  A  + +   +G           + G   S  S+   S+P P  + +E
Sbjct:   13 GAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQE----LSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVS--EDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNM-VTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQ-----PESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQT--EFGITSDKLLLAWREMEQAV-----ELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGD-----SQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNED--EKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEE 707          

BLAST of IKKbeta vs. SwissProt
Match: gi|75057117|sp|Q95KV0.1|IKKB_BOVIN (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB)

HSP 1 Score: 325.479 bits (833), Expect = 1.994e-98
Identity = 246/754 (32.63%), Postives = 386/754 (51.19%), Query Frame = 0

Query:   91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTD-EIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEA-GEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFS--------TLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGM---VGEIQAIPKDRPEDMQM--FVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFN------KKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMA----------SIPMPQHQGDEASMILYAENQALRAQ----LQEYMKIQYQ 808
            P    G +  + +LG+G FG V  W +Q++G+ +A+K+CR      LS ++RE+W  E+ I++RL HPNVV +  VP+ +  L   DLPL+ ME+C GGDLRK LN   +CCGL +G +L +  D+ASAL +LH  RIIHRDLKPEN+VLQ   +R I+K+IDLGYAKEL Q SL  SFVGTLQY+APEL   Q+YT +VDYWS G L+ E +TG RPFLPN  P QW  +V +K++ DI V   ED +  + F   L   N+L++ LA+  E WL+ +L W P++RG +   G  G FK L +IL+   + V+ +   G    Y + E    + L+  + +DTGI    Q LL   G  ++P++      S        TL+ +L  ++  S +T  +      +     P+++   L+ P++ +     + ++   +              Q  +  ++ LL     L+     +A   ++  +K + F+ S+  D EKY+EQ   +  ITS ++  AW + E+ +     ++  +  EV  ++  +  +   + ++Q  P  R +   +    +++ +    LR+ P + R + D+     Q MVR L Q  +  +           K  + K  +L  L +V     + + D  M  V + Q KRQ +LW LL  A     K     SG+  S+++S ++          + P    +  E S  L AE   L  Q    LQ+ MK Q Q
Sbjct:    8 PTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQE----LSPRNRERWCLEIQIMRRLNHPNVVAARDVPEGMQSLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEMDIVVS--EDLNGAVKFSSSLPHPNNLNSVLAQRLEKWLQLMLMWHPRQRGTDPVYGPNGCFKALDDILNLKLLHVLNM-VTGTLHTYPVTEDESLQSLKARIRQDTGILEEDQELLQEAGLALIPDKPAAQCLSDGKLNEGRTLDMDLVFLFDNSRVTYESQVSPQPQ-----PESVSCILQEPKRNLPFFQLRKVWGQVWHSIQALKEDCSRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYREQT--EFGITSDKLLLAWREMEQAV-----ELCGRENEVKHLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTDGDS-----QEMVRLLLQAIQGFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMSEDEKM--VVRLQEKRQKELWNLLKIAC---SKVRGPVSGSPDSMNASRLSHPCQLMSQPCTAPDSLPEAAEKSEDLVAEAHTLCTQLENALQDTMKEQDQ 732          

BLAST of IKKbeta vs. SwissProt
Match: gi|14285502|sp|Q60680.1|IKKA_MOUSE (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA)

HSP 1 Score: 322.013 bits (824), Expect = 3.656e-97
Identity = 220/684 (32.16%), Postives = 359/684 (52.49%), Query Frame = 0

Query:   91 PGTRLGE---YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCED-TDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGI-------FKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQ----KSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETL----AKVFSLVRLAQVNVDALIE--NLDLFMIQVSKCQRKRQSDLWKLLAAALQQ 751
            PG R G    +  + +LG+G FG V +++H++    +A+K CR      LS K+RE+W  E+ I+++L+H NVVK+  VP++L  L  D+PL+ ME+CSGGDLRK+LN P +CCGL + ++L++  D+ S + +LH  +IIHRDLKPEN+VLQ    +TI+K+IDLGYAK++ Q SL  SFVGTLQY+APELF ++ YT +VDYWS G +  E + G RPFL +L P  W E+++KK  +  C+  CE+ T E+ F  HL   NSL + + E  ESWL+ +L W+P++RG    G I +       F  +  IL+   V ++ +      + ++L        LQ+ +ER+TGI+ G Q LL   G  + P +   P    +   +R   C S +  L    K         ++L  C+    ++    L     + +++ A  + S          Q  +  +L LL    +L      +    ++  +K E F++S+  D E+Y EQ+     I+S +M +AW + E     +          + D +  ++  + E+Q  P  R +   M+   ++++   + L+  P +      T  ++ + +V  ++ +DR L++ F     L     K+  L+   +V +  + E  N  +FM      Q KRQ ++W LL  A  Q
Sbjct:    5 PGLRPGAGGPWEMRERLGTGGFGNVSLYQHRELDLKIAIKSCRLE----LSSKNRERWCHEIQIMKKLDHANVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK--CIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMESWLQLMLNWDPQQRG----GPIDLTLKQPRCFALMDHILNLKIVHILNMT-SAKIISFLLPCDESLHSLQSRIERETGINTGSQELLSETGISLDPRK---PASQCVLDGVR--GCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFRKSIQLDLERYSEQMTYG--ISSEKMLKAWKEMEEKAIHYSE--VGVIGYLEDQIMSLHTEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPPDHLYSDST--EMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFM------QGKRQKEIWHLLKIACTQ 660          

BLAST of IKKbeta vs. SwissProt
Match: gi|317373368|sp|O15111.2|IKKA_HUMAN (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA; AltName: Full=Transcription factor 16; Short=TCF-16)

HSP 1 Score: 317.775 bits (813), Expect = 1.140e-95
Identity = 225/735 (30.61%), Postives = 375/735 (51.02%), Query Frame = 0

Query:   91 PGTRLGE---YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCED-TDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGI-------FKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQ----KSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETL----AKVFSLVRLAQVNVDALIE--NLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQHQGDEA-SMILYAENQALRAQLQE 801
            PG R G    +  + +LG+G FG V +++H++    +A+K CR      LS K+RE+W  E+ I+++L H NVVK+  VP++L  L  D+PL+ ME+CSGGDLRK+LN P +CCGL + ++L++  D+ S + +LH  +IIHRDLKPEN+VLQ    + I+K+IDLGYAK++ Q SL  SFVGTLQY+APELF ++ YT +VDYWS G +  E + G RPFL +L P  W E+++KK  +  C+  CE+ + E+ F  HL   NSL + + E  E+WL+ +L W+P++RG    G + +       F  +  IL+   V ++ +      + ++L        LQ+ +ER+TGI+ G Q LL   G  + P +   P    +   +R   C S +  L    K         ++L  C+    ++    L     + +++ A  + S          Q  +  +L LL    +L      +    ++  +K E F +S+  D E+Y EQ+     I+S +M +AW + E     +          + D +  ++  + E+Q  P  R +   M+   ++++   + L+  P +      T  ++ + +V  ++ +DR L++ F     L     K+  L+   +V +  + E  N  +FM      Q KRQ ++W LL  A  Q        S    +V+    A +P    + D + S ++  ++    AQ+ E
Sbjct:    5 PGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLE----LSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK--CIFACEEMSGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRG----GPVDLTLKQPRCFVLMDHILNLKIVHILNMT-SAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGISLDPRK---PASQCVLDGVR--GCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYG--ISSEKMLKAWKEMEEKAIHYAE--VGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDST--EMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFM------QGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVVTPQDGETSAQMIE 711          

BLAST of IKKbeta vs. SwissProt
Match: gi|75073791|sp|Q95KV1.1|IKKA_BOVIN (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA)

HSP 1 Score: 312.768 bits (800), Expect = 8.203e-94
Identity = 214/685 (31.24%), Postives = 356/685 (51.97%), Query Frame = 0

Query:   91 PGTRLGE---YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCED-TDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGI-------FKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQ----KSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNK-------KETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQ 751
            PG R G    +  + +LG+G FG V +++H++    +A+K CR      LS K+RE+W  E+ I+++L H NVVK+  VP++L  L  D+PL+ ME+CSGGDLRK+LN P +CCGL + ++L++  D+ S + +LH  +IIHRDLKPEN+VLQ    + ++K+IDLGYAK++ Q SL  SFVGTLQY+APELF ++ YT +VDYWS G +  E + G RPFL +L P  W E+++KK  +  C+  CE+ T E+ F  HL   NSL + + E  E+WL+ +L W+P++RG    G + +       F  +  IL+   V ++ +      + ++L        LQ+ +ER+TGI+ G Q LL   G  + P +   P    +   +R   C S +  L    K         ++L  C+    ++    L     + +++ A  + S          Q  +  +L LL    +L      +    ++  +K E F +S+  D E+Y EQ+     I+S +M +AW + E     +          + D +  ++  + E+Q  P  R +   M+   ++++   + L+  P +      T  ++ + +V  ++ +DR L++ F         K+ +  +   V +A  N+    ++  +FM      Q KRQ ++W LL  A  Q
Sbjct:    5 PGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLE----LSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIMHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK--CIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRG----GPVDLTLKQPRCFVLMDHILNLKIVHILNMT-SAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSEMGISLDPRK---PASQCVLDGVR--GCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNTNLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYG--ISSEKMLKAWKEMEEKAIHYAE--VGVIGYLEDQIMSLHTEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDST--EMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEMALSNIKE-ADSTVMFM------QGKRQKEIWHLLKIACTQ 660          

BLAST of IKKbeta vs. SwissProt
Match: gi|82233772|sp|Q5ZJB4.1|IKKA_CHICK (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA)

HSP 1 Score: 312.768 bits (800), Expect = 1.335e-93
Identity = 217/680 (31.91%), Postives = 360/680 (52.94%), Query Frame = 0

Query:   91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN---EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRV------KLTMPKTLESCLKNPRKEVNRSLQKSIYSHA--YFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFN--DIRSKRQEVNDILGEVNGMVGEIQAIPKDR--PEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETL----AKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQ 751
            P    G +  + +LG+G FG V +++HQ +G  +A+K CR      LS K++++W  E+DI+++L HPNVV++  VP+++  L  D+PL+ ME+CSGGDLRK+LN P +CCGL + ++L++  D+ S + +LH  RIIHRDLKPEN+VLQ    + I+K+IDLGYAK+L Q SL  SFVGTLQY+APELF ++ Y+ +VDYWS G +  E + G RPFL NL P  W E+++KK  + I   + E   E+ F  HL   +S+ + + E  ESWL+ +L W+P++RG     E      F  +  IL+   V ++ +      + ++L        LQ  +E +TGI  G+Q LL+  G  + P +   P    +   +R    Y     + + DK K V        ++ + +   +++ + ++     + +++ A  Y    +E+   L   Q   +L L           NN   A Q+ +A  K E F +S+  D E+Y +Q+     I+S +M +AW + E   +      DI    +++  +  E+     E+Q  P  R   E M+   ++++   + L+  P +      T  D+ + +V+ ++ +DR L++ F     L     K+  L+   +V ++ + E  +  M    + Q KRQ ++W LL  A  Q
Sbjct:   22 PAGGCGPWEMRDRLGTGGFGNVCLYQHQDTGARVAIKSCRLE----LSVKNKDRWCHEIDIMKKLNHPNVVRACEVPEEMNFLVNDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIQYLHENRIIHRDLKPENIVLQDEGGKIIHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFENKSYSVTVDYWSFGTMVFECIAGFRPFLHNLQPFTWHEKIKKKDPKHIFASE-EMNGEVRFSTHLPQPHSICSLIVEPMESWLQLMLNWDPEQRGGGLDPETNSPKCFLLMDHILNLKIVHILNM-TSAKIVSFLLHPEESLHFLQNRIESETGISTGNQELLLETGICLDPRK---PASQCVIDGVRGWDSYM----VYLFDKSKTVYDGPFASRSLSECVNYIVQDSKIQLPIPQLRKVWAEAVHYVIGLKEDYSRLFQGQRAAMLSLLRYNANLIKMKNNMVSASQQLKA--KLEFFHQSIRLDLERYSDQMA--YGISSEKMLKAWKEMEEKASHCAQAEDIGYLDEQIMALHTEIV----ELQKSPYARRQGEVMESLEQRAIDLYKQLKTRPPDHAYSDST--DMVKIIVQTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKIEVALNNIKEADNSEM----QMQGKRQREIWHLLKIACTQ 674          

BLAST of IKKbeta vs. SwissProt
Match: gi|82183996|sp|Q6GM53.1|IKKA_XENLA (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA)

HSP 1 Score: 301.597 bits (771), Expect = 1.559e-89
Identity = 211/677 (31.17%), Postives = 361/677 (53.32%), Query Frame = 0

Query:   89 ISPGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN-EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRV------KLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQ--GLEDLRQI-PLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETL----AKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQ 751
            +  G   G +  + +LG+G FG V +++++++G++ A+K CR      LS K++E+W QE+ I++RL HPNVVK+  VP ++  L  D+P + ME+C+GGDLRK+LN P +CCGL + +VL +  D+ S + +LH  RIIHRDLKPEN+VLQ  + +T++K+IDLGYAK+L Q SL  SFVGTLQY+APELF ++ Y+ +VDYWS G ++ E + G RPFL N+ P  W E+++KK  + I  ++ E + EI F   L   N+L + + +  E+WL+ LL W+P +RG   + G    F  + +I S   V ++ +        + L+       LQ+ +ER+TGI   +Q LL+  G  + P +   P    +   ++    Y     + + DK K V        ++ + L   +++ + ++     + +++ A  + S          Q  +  +L LL    +L      +    ++  +K + F+ S+  D E+Y +Q+     I+S +M  AW + E     F      K  E++ +   + G+  EI  + +      Q  V + L+   +E  +Q+ P    K      ++ + +V+ ++ +DR L++ F     L     K+  L+   ++ V+  I+  D  ++Q+   Q KRQ ++W LL  A  Q
Sbjct:    6 VQHGAVCGPWDMKDRLGTGGFGNVCLYQNRETGELKAIKSCRLE----LSVKNKERWCQEIQIMKRLNHPNVVKACDVPPEMDFLVNDVPHLAMEYCAGGDLRKLLNKPENCCGLKESQVLNLISDIGSGIQYLHENRIIHRDLKPENIVLQECNGKTVHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFENKPYSVTVDYWSFGTMAFECIAGFRPFLHNMQPFTWHEKIKKKDHKHIYAYE-EMSGEIRFSTSLPEPNNLCSIIVDKIETWLQLLLNWDPVQRGGGIDCGRPRCFMLMDQIFSLKIVHILNMT-SAKIHSFHLQPEESLHTLQSRIERETGISTCNQELLLEMGVSLDPRK---PASQCVIDGVKGWDSYM----VYLFDKSKTVYEGPFQSRSLSECLNYIVQDSKVQLPIPQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRFNTNLTKMKNTMVSASQQLDAKLQFFKRSIEIDLERYSDQMA--YGISSEKMLRAWKEMEDKAVCF-----GKAGEIHFLDETIMGLHTEIVELQRSPCARRQGDVMEHLEQRAMELYKQLKPRSPDKAYSDSTEMVKILVQTVQGQDRVLKELFGHLSKLLGCKQKIIDLLPQIEMTVNN-IKEADSSLMQM---QAKRQREIWHLLKIACTQ 658          

BLAST of IKKbeta vs. SwissProt
Match: gi|119371145|sp|Q4G3H4.1|IKKA_DANRE (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA)

HSP 1 Score: 300.442 bits (768), Expect = 5.336e-89
Identity = 227/739 (30.72%), Postives = 382/739 (51.69%), Query Frame = 0

Query:   96 GEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTD-EIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRG---RNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKG-KDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLR-----IIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQ--GLEDLRQI--------PLEGRKEKDTVLDVAQNMVRCLKQRDRNLQD-YFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLA-AALQQKQKGDNGRSGNHQSVSSS------------PMASIPMPQHQGDEASMILYAENQALRAQL 799
            G +V + +LG+G FG V+++++Q++ + +A+K CR      L+ K++++W + + I+++L+H NVV +  VP++++ +   DLPL+ ME+CS GDLRK+L+ P +CCGL + EVL++  D+ S + +LH  +IIHRDLKPEN+VLQ  + + ++K+IDLGYAK+L Q SL  SFVGTLQY+APELF  + YT +VD+WS G +  E   G RPFL NL P QW  +V  K  +DI     ED + E+ F  HL   N+LS TL E  E  L+ +L+W+P +RG     ++ +   F  L +ILS   V +  ++    ++   L    +G   LQ  +E +T I + +Q LL   G    P +   P    +   +R     I+Y +       M     R   T+P+++   ++  + ++  S  K ++  A  +            Q  +  +L LL    +L      +    ++  +K + F+ S+ +D EKY +Q++    I+S +M +AW+++E     F     ++  E+  +  E+  +  EI  + +      Q  V + LQ   +E  +Q+        P  G  +   ++ V   +V+ ++ +DR L+D Y +  + L     ++ L    ++  +E +      V + Q KRQ + W LL  A  Q   +    +SG   S  S+            PM S+ +P H+GD  + +L  ENQ    QL
Sbjct:   13 GSWVMKERLGTGGFGHVYLYQNQETSEKIAVKLCRLE----LNSKNKDRWSRGIQIMKKLKHLNVVTAKDVPEEMMHIALNDLPLLAMEYCSKGDLRKLLSKPENCCGLKESEVLSLLNDVGSGIQYLHENKIIHRDLKPENIVLQEINGKLVHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFEGKSYTVTVDFWSFGTMIFECCCGFRPFLHNLQPVQWTSKVRNKGPKDIMA--VEDMNGEVRFSTHLPYPNNLSRTLLEPLEGLLQLMLKWDPVQRGLGLNTDSKQPQCFVLLDQILSMKVVHI--LNMTTTQVHSFLLSPDEGLHSLQQRIENETKIELLNQDLLQETGVMSDPRK---PAAQCVLDGVRGWDSYIVYLFDKSLTKYMGPLTAR---TLPESVNFIVRETKTQLPLSTLKKVWGEAVSYICGLREDYSRLFQGQRAAMLSLLRFNTNLTRYKNMMFSFSQQLKAKLDFFKTSIQYDLEKYSDQMQ--YGISSEKMLKAWHENEERAAAF-----AQVAEIGHLDEEIMALHSEIVELQRSPYARRQGDVMEQLQEKAIELYKQLKAKCKMPDPQHGYSDSSEMVKV---IVQTVQNQDRVLRDLYAHLSKILLSKQKIIDLFP-KIERTLECIKEADTTVMQMQIKRQREFWHLLKIACAQNTTRSSVSQSGEMPSSLSTWNQTQAQCSSRLPM-SLQVP-HEGDSVNHLL-EENQRYLTQL 723          

BLAST of IKKbeta vs. nr
Match: gi|1325307975|ref|XP_023335608.1| (inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X1 [Eurytemora affinis] >gi|1325307977|ref|XP_023335609.1| inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X1 [Eurytemora affinis])

HSP 1 Score: 459.914 bits (1182), Expect = 3.186e-147
Identity = 273/667 (40.93%), Postives = 391/667 (58.62%), Query Frame = 0

Query:   97 EYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEI--QAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVS---------KCQRKRQSDLWKLLAAALQ 750
            E+VC+ QLGSG FG+VHVWR+  + Q  ALKK +FG++  L+ +H+ QW QEVDI+ RL+H NVV+  S+P  L     DLP +CME+C  GDLR++LN   +C GL + ++L +  D+ SALG+LHNRRIIHRDLKPENVVL+ T  R +YKLIDLGYAKELG SSLA SFVGTLQY+APELFL Q+YTKSVDYWSLG L HEI+TG+RPFLP+LSPGQW++ VE+K +  I V +  D  +I ++E+L PE  +S  LA   E WLRSLL+W  +RRGR+  G + +F  L +IL   R+ V  + R      Y          LQ  +  DT I   +QLLL  +G +I  E+  L  F+  E  L I     S   L +++++K V+  +P  ++  L++ ++ V     K +  H Y F +QE R        LK L  ++ T I+D   +    +Q  +R  +  E F  SL HD  +Y EQ +K   ITS +M E+WN S  D+    + +R++   + + +      + E+  +    D P D  ++    +SL+  + LR+     R +  T  ++AQ +VR L++RD+ L          +    L +L ++ VD+L  N    ++  S         K Q +RQSD+W LLAAA++
Sbjct:    4 EWVCENQLGSGGFGIVHVWRNILTNQKYALKKFKFGSETLLTARHKTQWCQEVDIMLRLDHMNVVRCYSIPPGLDPGSTDLPSLCMEYCESGDLRRLLNKIENCRGLLESQILPVLNDVTSALGYLHNRRIIHRDLKPENVVLKSTQTRMVYKLIDLGYAKELGVSSLAKSFVGTLQYVAPELFLEQDYTKSVDYWSLGLLCHEIVTGQRPFLPHLSPGQWVDHVEQKLQNHIAVLETVD-GKIVYQENLVPETRISRKLALRLEDWLRSLLDWSAERRGRDTHGNVVVFTQLNKILREKRLDVFNL-RNKTVHCYAAETSFSFNHLQAQILADTNISAENQLLLTDHGYKITREDD-LDQFT--EAELPIFLVDMSSMSLKLSEQLKCVQFQIPVLVQQFLRDTKRSVQDYHLKLMNVHGYHFIAQECRTHELMAIGLKTLFSYIKTEIQDF--STLTFSQDLQRLEANMEFFTSSLNHDLSRYDEQAQKKDRITSVKMIESWNSSRTDILSSLDTLRTRTCILEESIKTAETGIREVERETTILDPPSDPALKELEGRSLRLYDGLRRERASNRVDT-TPREIAQIVVRMLRRRDQLLN---------STCSLLCKLRRLVVDSLDINQAAGVVSTSFQTLGESLIKAQTRRQSDIWTLLAAAIK 653          

BLAST of IKKbeta vs. nr
Match: gi|341650458|gb|AEK86518.1| (IKKbeta [Litopenaeus vannamei])

HSP 1 Score: 434.491 bits (1116), Expect = 5.461e-137
Identity = 255/726 (35.12%), Postives = 400/726 (55.10%), Query Frame = 0

Query:  104 LGSGSFGVVHVWRHQKSGQILALKKCRFGT-----DVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGR----NEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQGLED----LRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLL-------------AAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQHQGDEASMILYAENQALRAQLQEYM 803
            LG+G FG V +WRH  +G+ +ALKKCR+GT     +  L+ KH E+W +EV+I+ RL H  VV+   VP +L   + DLP++CME+CSGGDLRK+LN P +CCGL +  V +   D+  A+ +LH+ RIIHRDLKPEN+VLQ    +T+YKLIDLGYAKEL QSS+  SFVGTLQY+APELFLS+ YT +VDYWSLG ++HEI+TG RPFLPN++P +WM++V  K    +CV++  +  EI F  H+FPE  +S  L    E WLR +LEW+P  RG+    + A +   F  + +IL++  ++V  VD     L+Y + E T   ++Q W+ RD+G+ V  Q  L+P GQ   P    +  ++  + +  ++Y ++   G+T      +V    P  +E+ L+ PR  V    Q+ +++HA FF  +E R      Q+ KV +L L++    L    Q++     +  ++  LF E+L  D + Y EQ      +TS +++  W +         + +  + Q++   L  +N  + E+Q  P  R   +       L   ED    LR+   E R       D+ + +++ L++RDR  QD +   E  ++  S V      ++A++++       +S  Q++RQ D+WK++             A  +Q  Q   N      +  S + ++S+     +  + S  + AEN+A R Q+ E +
Sbjct:   19 LGTGGFGTVTLWRHNDTGETIALKKCRWGTPGTGTENILTPKHVERWEKEVEIMNRLNHQAVVRCFPVPDELTGPQGDLPMLCMEYCSGGDLRKVLNKPENCCGLREAAVRSCIRDMTEAVAYLHSMRIIHRDLKPENIVLQDVDGKTVYKLIDLGYAKELEQSSVCTSFVGTLQYLAPELFLSKRYTCTVDYWSLGLVTHEIITGIRPFLPNMTPVEWMKRVRTKQSHHVCVYEGRN-GEIQFSSHMFPECHISQPLRTRIEEWLRIMLEWDPVLRGQVLDEDSAKQFVAFNMINDILNKKMIKVFVVDL-CRLLEYEVTESTSLSEVQQWVARDSGVLVDDQRPLLPRGQPPDPTRPAIQCWAPPDEDEWLLYIFAE--GMTRP----QVPPHFPPLVEAMLREPRTAVEYQTQRRMWAHAVFFLHREARLLTLLTQAQKVSMLHLMSGHAQLTKTGQRMLSDIAKLQARHHLFMEALNTDLDYYDEQASSG-RLTSEKLYSGWREMGEVTLRQVHAVVERVQQLEGSLTALNTRILELQCSPFARARAIDSL-DSVLTAGEDHYCNLRRRNKEQRATPHDNTDMCKLLLQALRKRDRLQQDLYKHVEKQSECCSEVAALSSPLEAVLQDAARTAQHISSLQKQRQKDIWKIMEIAINHSRTVGTAAGMVQAPQPVPNASQLPKKPPSPAVLSSLNNLLEKSKKESDAIIAENRAXRCQMVEML 734          

BLAST of IKKbeta vs. nr
Match: gi|1228009951|ref|XP_021936901.1| (inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [Zootermopsis nevadensis] >gi|646699581|gb|KDR10135.1| Inhibitor of nuclear factor kappa-B kinase subunit alpha [Zootermopsis nevadensis])

HSP 1 Score: 432.565 bits (1111), Expect = 4.075e-136
Identity = 257/681 (37.74%), Postives = 395/681 (58.00%), Query Frame = 0

Query:   95 LGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRG----RNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEI-LPEESL---LPMFSTLEPNLRIIYCY--SSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQG---LEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQD-YFNKKETLAKVFSL-VRLAQV--NVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNG 758
            +  +V +  LGSG FG V +WRH+   +++ALKKCR GTD  L+EKH+E+W +EV+I+QRL HPNVVK+++VP DL  L   LPLMCMEFCS GDLR++LN   +CCGL + EV ++  D+ SA+ +LH+ +I HRDLKPEN+VLQ    R +YKLIDLGYAKEL QSS+  SFVGTLQY+APELF+S+ Y  SVDYWSLG +SHE++TG RPFLPN++P  WM  V +K+  DIC ++ ED   I F + LF +N +S+ L    E WL+ LLEW+  +RG    RN+  +I +F  + +ILS+  + V  V    N L Y + + T    LQTW+ERDT I V  Q LL+ +GQ   + +E+    +P     +    ++Y Y   SL        I+    ++P+T+   ++ PR +V    QK  ++HA FF  QE      F Q+ +V +L +++    LN   Q +    ++  ++ +L  ESL  D    ++Q KK +   S ++  +W++    +      ++    ++       NG   ++Q  P  +  D ++ +    +G    + LR+ P E R E+   +++ + +  CLK RD+ L+D  FN    L +V  + + + Q+   +++ ++ ++   +++ + Q  RQ D+W      LQ  Q   NG
Sbjct:   12 VANWVRERVLGSGGFGQVTLWRHKTKDEMIALKKCRTGTDAILTEKHKERWSKEVEIMQRLNHPNVVKAIAVPPDLAVLRSKLPLMCMEFCSKGDLRQVLNRSENCCGLCEAEVRSLISDVKSAVQYLHSMKITHRDLKPENIVLQQEEDRIVYKLIDLGYAKELDQSSICTSFVGTLQYLAPELFMSKTYNYSVDYWSLGLVSHEVITGVRPFLPNMAPVSWMTHVREKSSDDICAYKAED-GTIVFSKELFLQNHISSCLKCYVEKWLKLLLEWDAAKRGRILNRNKELQIVVFDLIEDILSKKIINVFSVPSYQN-LSYEIDDSTAVSTLQTWIERDTRIPVQEQELLLSSGQPFDISKEACQCWVPQTLNNQNVNTMVYVYHRGSLA-------IQNFAPSVPQTVSKMMEEPRNKVEFVHQKRAWAHAVFFLQQEMELYHAFLQAYRVKMLHVISSNAKLNEQTQAVVSHLQQVEAQLQLILESLHFD----EDQAKK-IGFFSEEVMHSWSKMNASVGRRIAKLKEIVSQLESKCDVANGKTMDLQRNPYTKMADHEVLMSLLEEGQKRYDSLRRRPKENRYEQTDNVEMVKIVYNCLKHRDKLLRDKTFNAH--LQQVIDVQMEIEQLWNPLNSSVQVINKVQMELKQTQLDRQHDIW------LQMTQDSCNG 670          

BLAST of IKKbeta vs. nr
Match: gi|1350353424|gb|AVI10168.1| (inhibitor of nuclear factor kappa-B kinase beta [Scylla paramamosain])

HSP 1 Score: 431.024 bits (1107), Expect = 1.361e-135
Identity = 258/737 (35.01%), Postives = 406/737 (55.09%), Query Frame = 0

Query:  104 LGSGSFGVVHVWRHQKSGQILALKKCRFGT-----DVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIG-----IFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDF----FNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRP---EDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQH--------------------QGDEASMILYAENQALRAQLQEYM 803
            LG+G FG V +WRH  +G+ +ALKKCR+GT     +  L+ KH E+W +EV+I+ RL H  VV+   VP +L     DLP++CME+CS GDLRK+LN P +CCGL +  V A   D+  A+ +LH+ RIIHRDLKPEN+VLQ    + +YKLIDLGYAKEL  SS+  SFVGTLQY+APELFLS+ YT +VDYWSLG ++HEI+TG RPFLPN++P +WM++V  K    ICV++  + D + F  H+FPE+ +S+      E WLR +LEWEP  RG+ + GE G      F  + +IL++  ++V  VD     L+Y + E +   ++Q W+ +D+G+ +  Q  L+P GQ   P    +  ++  + +  ++Y ++   G+T      +V    P  +E+ L+ PR  V+   Q+ ++SHA FF  +E R      Q+ KV +L L++    L    Q++     +  ++  LF E+L  D + Y EQ      +TS +++  W    RD+ +      + +  + Q++   L  +N  + E+Q  P  R    + ++  +    +    +R+   E R       D+ + +++ L++RDR  QD F   E  ++  S V      ++ ++E+       +S  Q++RQ D+WK++  A+      ++ RS  + S   + M  IP  +H                     G EA  I+ AEN+ALR Q+ E +
Sbjct:   21 LGTGGFGTVTLWRHTDTGETIALKKCRWGTPGTGTENILTPKHVERWEKEVEIMNRLSHSAVVRCFQVPAELTGPPGDLPMLCMEYCSLGDLRKVLNKPENCCGLREASVRACIRDITEAVAYLHSMRIIHRDLKPENIVLQDVDGKIVYKLIDLGYAKELDHSSVCTSFVGTLQYLAPELFLSKRYTCTVDYWSLGLVTHEIITGVRPFLPNMTPVEWMKRVRTKQSNHICVYEGRNGD-VQFSAHMFPESHISSPFRLRLEEWLRVMLEWEPGVRGQVQ-GEDGSKKVLAFTMINDILNKKMIKVFVVDLCC-LLEYEVTESSSLSEVQKWVAQDSGVAIEDQRPLLPRGQPPDPTRPAIQCWAPPDEDEWLLYIFAE--GMTRP----QVPPHFPPLVEAMLREPRTTVDYQTQRRMWSHAMFFLQREARLLALLMQAQKVSMLHLMSGHAQLTKTGQRMLSDIAKLQARHHLFMEALNTDLDYYDEQASSG-RLTSEKLYSGW----RDMGEITLRQVHVVVERVQQLEGSLTALNTRILELQCSPFARARSNDTLENIISAGEELYCTMRRRNKEQRATAHDNTDMCKLLLQALRKRDRLQQDLFKHIEKQSECCSEVAELSSPLETVLEDAARTAQHISSLQKQRQKDIWKIMEIAI------NHSRSVGNPSSLPANMQPIPNAKHLAKKPPSPAALSSLSALLEKSGKEADAII-AENRALRCQMVEML 736          

BLAST of IKKbeta vs. nr
Match: gi|1339046424|ref|XP_023711368.1| (inhibitor of nuclear factor kappa-B kinase subunit alpha [Cryptotermes secundus] >gi|1339046426|ref|XP_023711369.1| inhibitor of nuclear factor kappa-B kinase subunit alpha [Cryptotermes secundus] >gi|1330905953|gb|PNF29865.1| hypothetical protein B7P43_G09538 [Cryptotermes secundus])

HSP 1 Score: 426.402 bits (1095), Expect = 1.058e-133
Identity = 247/663 (37.25%), Postives = 373/663 (56.26%), Query Frame = 0

Query:  104 LGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGR----NEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPN------LRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQ---AIPKDRPEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENL-----------DLFMIQVSKCQRKRQSDLW 742
            LGSG FG V +WRH+   +++ALKKCR GTD  L+EKH+E+W +EV+I+QRL+HPNVVK+++VP DL  L   LPLMCMEFCS GDLR++LN   +CCGL + EV  +  D+ SA+ +LH+ +I HRDLKPEN+VLQ    + +YKLIDLGYAKEL QSS+  SFVGTLQY+APELF+S+ Y  SVDYWSLG +SHE++TG RPFLPN++P  WM  V +K+  DIC +Q +D   I F + LF +N +S++L    E WL SLLEW+  +RGR    N+  EI +F  + +ILS+  V +  V      L Y + + T    LQ W++RDTG+ V  Q LL+P+GQ     +     +   +P+      +  ++ + SL        I +V  ++P T+   +++PR  V    QK  ++HA FF  QE      F ++ +V +L ++     LN   Q +  + ++  +++ LF +SL      + E   K +      +  +W      L+     ++    ++      VN    ++Q    I +D  E +   ++   +  ++LR+ P E R+E+   +++ + +  CLK RD+ L D           F       V+V A IE L           +   +++ + Q  RQ D+W
Sbjct:   18 LGSGGFGQVTLWRHKTKDEMIALKKCRTGTDALLTEKHKERWSKEVEIMQRLDHPNVVKAIAVPPDLAVLRSKLPLMCMEFCSKGDLRQVLNRSENCCGLCEAEVRLLISDVKSAVQYLHSMKITHRDLKPENIVLQQVKDKIVYKLIDLGYAKELDQSSICTSFVGTLQYLAPELFMSKTYNYSVDYWSLGLVSHEVITGVRPFLPNMAPVSWMTHVREKSSDDICAYQAQD-GSIVFSKELFHQNHISSSLKYHMEKWLTSLLEWDAAKRGRAINKNKELEIVVFDMIEDILSKKIVNIFSVP-TYQHLSYEVDDSTAISTLQLWMKRDTGVPVEQQELLLPSGQPFDMTKEACQCWVPPDPHNQSSKPMVYLFLHGSLA-------IGKVTPSIPVTVGKMMEDPRHRVEYIHQKRAWAHAVFFLRQEMELYQTFMEAYRVKMLHIILNNARLNEQAQAVVSRLQQVEAQFHLFIDSL-----HFDEDEAKRIDFFPEHIVHSWTTVSSALSVRMAKLKEVVSQLQSKCDVVNSRTIDLQRNTCIKRDH-EVLVSLLETGQKRYDNLRRRPKESRQERTDNVEMVKVVYNCLKHRDKLLND---------NAFDTHLQQVVDVQAEIEQLWNPLRSSLQVMNKVQMELRQMQLDRQRDIW 656          

BLAST of IKKbeta vs. nr
Match: gi|1355995747|gb|PRD35841.1| (chuk [Nephila clavipes])

HSP 1 Score: 395.586 bits (1015), Expect = 7.049e-122
Identity = 231/694 (33.29%), Postives = 384/694 (55.33%), Query Frame = 0

Query:   91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDE-IHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFV---KKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQHQ 780
            P   +G++  +  LG+G FG V +WR++ S + +ALK+CR+G D  ++ KHR +W+ EVD++ RL HPNVV +++VP +L     ++PL+ ME+CS GDLRK+LN P +CCGL +  V  I   ++SA+ +LH+ RIIHRDLKPEN+V+Q  +  TIYKLIDLGYAKEL Q S   SFVGTLQY+APELF+SQ+YT +VDYWSLG L+HEI+TG+RPFLP+ SP +W+  +  K K    +    D D+ I F + + P + + +    D E WL+++LEW+PK+RG+ E+G    F  L  +  +    V CVD       +I+ E    +D    LE++T I V  Q +  P+G     +E +    S +E    I++ ++     + +  I      +P  +E+ ++NP  +VN   Q++I+S A + S QE+       Q+ K  ++ LLT+   +  +  ++  +  + ++K  LF+ SL  D + Y++Q  ++   ++  + E W  +  +L    + +R K   +      +     E+Q  P  R +    F    +K L    +LR+   + R+     +++ + +  CL+      +D     + + ++   +      +  L++ +  +  Q+   Q KRQ  LWK++ A +++ Q  +  RS +   +SSSP     +P+ Q
Sbjct:    6 PVEEIGQWKKEKVLGAGGFGYVVLWRNKISNETIALKECRWGHDPMMTPKHRSRWKLEVDMMSRLNHPNVVTAIAVPPELDVPATEMPLLAMEYCSNGDLRKLLNKPENCCGLKEMHVRLIMKHISSAVNYLHSLRIIHRDLKPENIVIQDQNGNTIYKLIDLGYAKELDQGSFCTSFVGTLQYLAPELFMSQKYTCTVDYWSLGLLTHEIITGQRPFLPDKSPAEWIPII--KGKNSTVIRAYLDADKNIIFSDEIAPFHHICSIFKTDVERWLQTMLEWDPKKRGKYESG--SAFNLLETMFQKKISHVFCVDTLTLH-SFIINETMSLEDFYKELEKETKIPVSQQEIFSPDGHSSELKEGVSQFVSDMEEEETIVFLFNK--NESQSSMITSSSTVIPSDVENMMRNPHDKVNYQQQRNIWSQAVYLSQQESSLINKLIQAFKANLMSLLTKASYVRKSISRMTAEMNKLLAKCSLFKSSLEQDIKSYEKQ-SQNGGFSAETLLEDWKSNFENLKK-VDILRQKIVNLEACTSNIATRTAELQKSPYVRSKQSTSFEDVHQKILNSFAELRKRSSDERRIPHDNVEIVRLLCLCLQHSHTLTEDVIIHIKIVKQIKRDIDDCLPQIGNLLKEISDWEFQIDSWQSKRQQALWKVINALIEKAQHAE--RSISPLVLSSSPQT---LPKRQ 685          

BLAST of IKKbeta vs. nr
Match: gi|1325307979|ref|XP_023335610.1| (inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X2 [Eurytemora affinis])

HSP 1 Score: 390.193 bits (1001), Expect = 4.032e-121
Identity = 242/610 (39.67%), Postives = 348/610 (57.05%), Query Frame = 0

Query:  154 RLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEI--QAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVS---------KCQRKRQSDLWKLLAAALQ 750
            RL+H NVV+  S+P  L     DLP +CME+C  GDLR++LN   +C GL + ++L +  D+ SALG+LHNRRIIHRDLKPENVVL+ T  R +YKLIDLGYAKELG SSLA SFVGTLQY+APELFL Q+YTKSVDYWSLG L HEI+TG+RPFLP+LSPGQW++ VE+K +  I V +  D  +I ++E+L PE  +S  LA   E WLRSLL+W  +RRGR+  G + +F  L +IL   R+ V  + R      Y          LQ  +  DT I   +QLLL  +G +I  E+  L  F+  E  L I     S   L +++++K V+  +P  ++  L++ ++ V     K +  H Y F +QE R        LK L  ++ T I+D   +    +Q  +R  +  E F  SL HD  +Y EQ +K   ITS +M E+WN S  D+    + +R++   + + +      + E+  +    D P D  ++    +SL+  + LR+     R +  T  ++AQ +VR L++RD+ L          +    L +L ++ VD+L  N    ++  S         K Q +RQSD+W LLAAA++
Sbjct:    3 RLDHMNVVRCYSIPPGLDPGSTDLPSLCMEYCESGDLRRLLNKIENCRGLLESQILPVLNDVTSALGYLHNRRIIHRDLKPENVVLKSTQTRMVYKLIDLGYAKELGVSSLAKSFVGTLQYVAPELFLEQDYTKSVDYWSLGLLCHEIVTGQRPFLPHLSPGQWVDHVEQKLQNHIAVLETVD-GKIVYQENLVPETRISRKLALRLEDWLRSLLDWSAERRGRDTHGNVVVFTQLNKILREKRLDVFNL-RNKTVHCYAAETSFSFNHLQAQILADTNISAENQLLLTDHGYKITREDD-LDQFT--EAELPIFLVDMSSMSLKLSEQLKCVQFQIPVLVQQFLRDTKRSVQDYHLKLMNVHGYHFIAQECRTHELMAIGLKTLFSYIKTEIQDF--STLTFSQDLQRLEANMEFFTSSLNHDLSRYDEQAQKKDRITSVKMIESWNSSRTDILSSLDTLRTRTCILEESIKTAETGIREVERETTILDPPSDPALKELEGRSLRLYDGLRRERASNRVDT-TPREIAQIVVRMLRRRDQLLN---------STCSLLCKLRRLVVDSLDINQAAGVVSTSFQTLGESLIKAQTRRQSDIWTLLAAAIK 595          

BLAST of IKKbeta vs. nr
Match: gi|1316175393|ref|XP_023233196.1| (inhibitor of nuclear factor kappa-B kinase subunit alpha-like [Centruroides sculpturatus] >gi|1316175395|ref|XP_023233197.1| inhibitor of nuclear factor kappa-B kinase subunit alpha-like [Centruroides sculpturatus] >gi|1316175397|ref|XP_023233198.1| inhibitor of nuclear factor kappa-B kinase subunit alpha-like [Centruroides sculpturatus])

HSP 1 Score: 390.963 bits (1003), Expect = 5.305e-120
Identity = 239/723 (33.06%), Postives = 396/723 (54.77%), Query Frame = 0

Query:   89 ISPGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRS-KRQEVNDILGEVNGMVGEIQAIPKDR---PEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSV----SSSPMASIPMPQHQGDEASMILYAENQALRAQLQEYM 803
            +  GT +  ++    LG G FG+V +W+ + S + +ALK+CR+G D  ++ KH+ +W+ EVDI++RL HPNVVK++ VP  L   E +LPL+ ME+CSGGDLRK+L+   +CCGL + EV  +   +A+A+ +LH++RIIHRDLKPEN+VLQ    + IYKLIDLGYAKEL Q SL  SFVGTLQY+APELF+  +Y+ +VDYWS G ++HE++TG+RPFLP+++  QWM+ V  KTK  I     ++  ++ F E L P   ++    +D E WL+ +L+W P RRGR   G++  ++ L +IL++  ++V C +         + +    +++Q   E +TGI    Q +L+PNG    P ++ + +++  E    I++    L+     ++    KL +P  +    ++PR  ++  LQKS ++ A +    E        Q+ K+ +  +++          KIA +K    +K E F+ SL  D +KY+EQ + +  ITS +M + W +S   +  F N +R     E+N    ++  +  E Q  P +    P+ ++   +K L     L++   E R      +++ Q +   ++Q+D+ L D F+    L ++   +   Q  +++L   +  F  +V   Q  RQ+DLW +L   +  K K    +S ++Q V    S + +AS         +A  +  A N  +      Y+
Sbjct:    8 VEVGTEIDGWIRGPILGHGGFGMVILWKKKDSTETIALKQCRWGHDAMMTPKHKHRWKLEVDIMKRLSHPNVVKALEVPPALDVPETELPLLAMEYCSGGDLRKVLSKSENCCGLNEREVKNLIKHIAAAIKYLHSQRIIHRDLKPENIVLQEMDNKIIYKLIDLGYAKELDQGSLCTSFVGTLQYLAPELFMQNKYSNTVDYWSFGLVAHEVITGQRPFLPHMNTPQWMQHVSNKTKNHIGA-ILDEEGKVMFVEELSPFVKITNIFKKDMEMWLKLMLDWNPFRRGR--EGDMTTYELLDQILNKKVIQVFCTE-SCRLFALEVEDNVSLEEIQVLFESETGIPKNEQEILLPNGSFPDPNKNAVQLWTNPEEGESIVF----LSKKCNFNEFSGTKLCIPPLVARMTRSPRLTMDYELQKSAWTQALYLCHNERTVCQKLLQAYKINVEHIVSINSVTYKAMSKIAIEKNCLSAKVEFFKISLEKDLKKYEEQARNN-GITSNKMHDKWKKSFDLIEKFENLLRKIAHLEINSANAKIKTV--EFQKNPYNHLVLPKHLEDIYQKILDAYHRLKRKTQEQRNIPSDNVEMVQLVCSYIQQKDKVLGDIFSSLVNLKQMKKDIIELQPKLESLALEIQEFSKEVQTAQLMRQNDLWTILEYTI-DKLKMTMPQSSSNQRVTERHSQTSLASFSQQNSFHPQAEPMTSANNSYMDQSYANYL 718          

BLAST of IKKbeta vs. nr
Match: gi|1067099801|ref|XP_018011979.1| (PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit beta-like [Hyalella azteca])

HSP 1 Score: 387.497 bits (994), Expect = 2.737e-119
Identity = 247/729 (33.88%), Postives = 375/729 (51.44%), Query Frame = 0

Query:   98 YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGT-------DVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAG------EIGIFKDLGEILSR--VRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIP---KDRPEDMQMFVKKSLQGL--EDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGN---HQSVSSSPMASIPMPQHQGDEASMILYAENQALRAQLQEYM 803
            +V +  LG+G FG V +W+++ SG+ +ALKKCR+G        +  LS +H+E+W++EV I+ RLEHP VV    VP +L     DLP++CME+CSGGDLRK+LN P +CCGL +  V +   DL  A+ +LH++RIIHRDLKPEN+VLQ    +T YKLIDLGYAKEL  +S+  SFVGTLQY+APELFLS+ Y+ +VDYWSLG + HEI+TG RPFLPN+SP +WM++V  K    ICV++    D IHF E +F EN +S  L    E+WL+ +LEWEP RRG+ E        ++  F  +  +L++  + V VVC              VT  +D   WL     ++V     L P          + P F TL                                +E  L++PR  V  +LQ+ ++ H+ +F  +EN+       + K+ +L LL+R  ++    Q++     +  ++  LF E+L  D + Y  Q  +   +TS + + AW           +    K Q ++  L  +N  V E+   P      P D    +  S + L     R+   E  +  D+   + + +++ L++RDR  QD +   E      S V    V ++ L+ ++      +S  Q+ RQ D+WK++A      +    G  G           P+ ++ +   Q  E +  + AEN+ALR Q+ E +
Sbjct:   28 WVKEKVLGTGGFGTVTLWKNENSGETVALKKCRWGNTGSPASPETLLSPEHKERWQKEVQIMLRLEHPCVVSCFPVPSELEGGPGDLPILCMEYCSGGDLRKLLNRPENCCGLREVVVRSCLKDLTEAVAYLHSQRIIHRDLKPENIVLQENEGQTRYKLIDLGYAKELEYTSVCTSFVGTLQYLAPELFLSKRYSCTVDYWSLGLVVHEIVTGVRPFLPNMSPVEWMKRVRSKKSCHICVYEGRSGD-IHFSERMFDENHISKPLKSGLEAWLQLMLEWEPARRGQVEGAKPDDKKQVVAFTRMAALLNKKIIGVLVVC-------------GVTNEED--DWL-----LYVFSTCALTPQ---------VAPHFPTL--------------------------------VEEMLRSPRALVEHALQRRMWCHSLYFLYRENKLLSALISAQKIAMLHLLSRHAEVTRCGQRVLNDIAKLQARHHLFMEALNTDLDHYTSQSPQ-ARVTSEKAYGAWRGGGEATLSAVHAAVDKTQRLDAALTALNTKVMELNGSPFSCAKTPTDTLDTIVSSCEELYVSLRRRSRDERSRPHDSTA-MCKLLLQALRKRDRLYQDLYTHIEKQWSCLSEVTALAVPLEELLADIARAAQTISSLQQHRQDDIWKIMAIVASHSRGNVAGAPGGDLPRAPAPPQPLTNLALLLEQSSEQTDNIIAENRALRCQMVELL 692          

BLAST of IKKbeta vs. nr
Match: gi|321470783|gb|EFX81758.1| (hypothetical protein DAPPUDRAFT_317376 [Daphnia pulex])

HSP 1 Score: 381.333 bits (978), Expect = 3.460e-117
Identity = 241/729 (33.06%), Postives = 389/729 (53.36%), Query Frame = 0

Query:   95 LGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN-------EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILRE--VTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLT--MPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDI-------LGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQHQGDEA--SMILYAENQALRAQLQEYM 803
             GE+  +  LGSG+FG V +  ++++G+ +A+KK    +           W +E+DIL  L+HP +V S+ VP DL  L  D P++CME+C+GGDLR++LN P +CCG+P+ +VL I  D++SA+ +LH+ +++HRD+KPENVV+Q T ++  YKLIDLG AK L + SL  + VGTLQY+APELF  ++Y  +VDYWSLG + HE +TG RP LP   P  WM+  E+KT  DIC++    + EI F + LF EN LS+ +    E WL+ +LEW P  RGR+         G I  F  L ++L+   V +  V+ G   L YI+ +  VT  + +  W+ERDTGI   +QLL++P G      +S    F + E  L  +  +S     +        KLT   P+ LE+ L NPR+E    +QK +++ + FF + ++      + +LK+   ++  R   L      I      A+S+ +LF  SL  D+  Y+ Q ++   + S  + E WN+ E  L++   +++S+   +  +       + E   + G   A P    ++       +L+   DL++   E +++ +  + + + +V+  K R +   D F +   + K  + V      +  L   +D F  Q+   Q  RQ+D+W LL  A+   Q+          + S   + +IP    + DEA  SM++  ENQ+LR Q+Q+ +
Sbjct:   13 FGEWKLERLLGSGAFGKVLLMINRQTGEKIAVKKIHRDSPFVADNN----WDKELDILHHLKHPGIVASLPVPPDLRSLSCDAPILCMEYCNGGDLRQVLNKPANCCGIPEMDVLDILRDISSAVVYLHSVKVVHRDIKPENVVIQQTEEKKFYKLIDLGMAKNLNKQSLCHTLVGTLQYLAPELFSCEKYNNTVDYWSLGVVIHECITGVRPVLPGQPPVVWMQHAERKTHSDICIYS-HPSGEIVFSQKLFKENHLSSVVQAQMEEWLKLMLEWNPAMRGRHWVPDASRPPGPIVAFGLLEKVLTTEVVSIFWVE-GLALLSYIVSDDNVTM-ETIHEWIERDTGISPRYQLLVLPRGYASDSGKSARQFFGSEE--LGNVCLFSKFNDGS------ECKLTQVYPEFLETMLANPREEFEYRIQKRMWAQSVFFINHQSTLYRKLNHALKIHSTYMTVRASLLKQQTDFINGALRHAVSRHDLFTSSLKQDQYNYKLQAQRG-GLPSCTLLEKWNKEEFTLSNKLAELQSRCTTLEQVVQRTVSGVAEAAKLAGVFLAKPSVALDNCSQL---ALELYSDLQKRSAEQKQQMENNVAMTKVVVKAFKNRSQLFTDCFTQIRVVEKASADVDSFLPQLIVLKNEIDQFQDQIFVFQTSRQNDVWTLLERAVTLWQR--TSMINQPHAASEPSLLNIPSLSLREDEARESMVVIQENQSLRYQIQDTL 720